(GNB2L1) guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 [Homo sapiens] |
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Gene
Transcript(s)
Exon(s)
Protein(s)
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Accession
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3594
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Official symbol
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GNB2L1
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Official name
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guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
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Gene type
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gene with protein product
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Organism
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Homo sapiens
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Location
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Chromosome 5 (NC_000005.9) : 180663927...180670905 (-)
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Map
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5q35.3
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Length
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6979 nt
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NM_006098.4
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GNB2L1, mRNA isoform 1
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Accession
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Name
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Organism
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Length
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P63244
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Guanine nucleotide-binding protein subunit beta-2-like 1
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Homo sapiens
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317 aa
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D3DWS0
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Guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1, isoform CRA_a [submitted name]
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Homo sapiens
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317 aa
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Synonyms |
PIG21; HLC-7; RACK1; H12.3; Gnb2-rs1
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Alternative name(s) |
proliferation-inducing gene 21; lung cancer oncogene 7; protein homologous to chicken B complex protein, guanine nucleotide binding; Receptor for Activated C Kinase 1
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Related Articles in PubMed
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Go to ensembl
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1 |
TCTCTTTCAC |
TGCAAGGCGG |
CGGCAGGAGA |
GGTTGTGGTG |
CTAGTTTCTC |
TAAGCCATCC |
AGTGCCATCC |
TCGTCGCTGC |
|
81 |
AGCGACACAC |
GCTCTCGCCG |
CCGCCATGAC |
TGAGCAGATG |
ACCCTTCGTG |
GCACCCTCAA |
GGGCCACAAC |
GGCTGGGTAA |
|
161 |
CCCAGATCGC |
TACTACCCCG |
CAGTTCCCGG |
ACATGATCCT |
CTCCGCCTCT |
CGAGGTACGG |
ACTAAGGTAG |
ATTTCAGGAC |
|
241 |
CCGAGATTGC |
AGGGCTGGGG |
GATTCCGCGT |
GTCGTGTAGG |
GAATTCCGCG |
TGTGGTGTGG |
CAGGCCGGTG |
GCGCGCGAGT |
|
321 |
TGGCGGGGAC |
TGACAGACTT |
CTCTGCCCCA |
TTGTGAATTG |
GGGCGTGCGG |
ACCCGAGCCT |
AGGCCTCAAC |
CCGGGCGAAC |
|
401 |
CACATTGCAG |
ATGAGAACCT |
ACGTGTACAT |
CAGCTCGCAG |
CTGCTAGGAG |
GGTTGGAGAG |
TTGGAAACTT |
TTAAAATATC |
|
481 |
TTTTGCCTTC |
TCCTTCGTAG |
TGTGGCCGGG |
GGCCTACGGG |
CCGGGCGGGG |
CGGTGATGAC |
CCCAACATGC |
CATCTGAGTG |
|
561 |
TCGGTGCTGA |
AATCCAGAGG |
CTGTTTCTGA |
GCTGCCGCCC |
GGCCCAAGGC |
TCGTGGGGAG |
GCAGGTGGAC |
TCCAGAGGAC |
|
641 |
CTCGTGGCTC |
AAGTGTCGGC |
CTACTTTTTC |
TGCCCCTGGT |
TCTCCCCGTC |
CCTATCCCTG |
TGTTCCTGAC |
TGCGTTTAGA |
|
721 |
CGCTTCTTGT |
GCTTCCGCTT |
TGCTGCTACA |
CTGTTAAGAA |
TTGTCTGACT |
TTTGAATCAT |
GTCTGGCTGT |
TAATCGTAAA |
|
801 |
ATTTGTTGAG |
TGGGACAGGT |
TTCAGTAAAA |
GCATCCAATC |
CTGTAGCGCC |
TGAAGTGGCT |
TTTCCAGCAT |
TCATTACTAC |
|
881 |
ATTTCTGTCG |
GCCCTCAGAG |
GTAGGCATAG |
GAGGCCCCAG |
CTACTCTACA |
GCCACAAACT |
GCTGTGCATT |
TGGTTGCAGA |
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961 |
GAAGACACAA |
AGTGGCTGTT |
GAGTTCGTCT |
GAGTTTCAGG |
AAAGGGTGTC |
TGTATTTCTG |
GCACCTAAAT |
TAAGTTCTCA |
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1041 |
GGATACAGGC |
TGGGCGCGGT |
GGCTCACGCC |
TATAATCCCA |
GCACTTTGGA |
AGGCAGAGGC |
GAGTGGATCA |
CTTGAGATCA |
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1121 |
GGAGTTAGAG |
ACTAGCCTGG |
CCAATGGTGA |
AACCGCATCT |
CTAGTTAAAA |
AATTAGCCAG |
ACGTGCTGGC |
AGGTGCCAGC |
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1201 |
TGGCCAAGTA |
ATCCCAGCTA |
CTTGGGAGGC |
TGAGGCGGGA |
GAATTGCTTG |
AACACGGGAG |
GTGGAGTTTG |
GAGTGAGCCG |
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1281 |
AGATCATGCC |
ACTGCACTCC |
AGCCTGGGCG |
ACAGAGCGAG |
ACTCCATCTC |
AAGAAAAAAA |
AAAGTTATCA |
GGGTACAGTT |
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1361 |
TACCTCTACG |
TGCGTTTTTA |
GTCTGGAATA |
GAGCCACTCA |
GTCCTGGTCT |
GTAACTGCTC |
TTGTCTGTTG |
TTTCCATCCC |
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1441 |
TCCTTAAGCG |
TCCTTAGTTG |
TTGTTAACCC |
ACTCATGACC |
TTGACACTTA |
GTGAATTATC |
CAGTGTGTTA |
AACGGGCTGC |
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1521 |
GGGTTCCTCA |
CTGATTTTTC |
TTCTGTTTTA |
CCTCCTTTAG |
ATAAGACCAT |
CATCATGTGG |
AAACTGACCA |
GGGATGAGAC |
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1601 |
CAACTATGGA |
ATTCCACAGC |
GTGCTCTGCG |
GGGTCACTCC |
CACTTTGTTA |
GTGATGTGGT |
TATCTCCTCA |
GATGGCCAGT |
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1681 |
TTGCCCTCTC |
AGGCTCCTGG |
GATGGAACCC |
TGCGCCTCTG |
GGATCTCACA |
ACGCAAGTAG |
CTGCTCACTT |
AGCTCTGGGG |
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1761 |
CCTTGGGAAG |
AATCTGGGCA |
GAAGTGAGGT |
GGATGCAATT |
GGCTGGTTTC |
CCAGGGGAGA |
TCCAGTCCAT |
TTGGGAACTG |
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1841 |
GAAAGCAGAG |
CACACCTACA |
GAAGATGTTT |
GGCCTCCCTC |
ACTTTAAATA |
AGTTACTCAG |
CATTGCTGAG |
GAGTGTGGCT |
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1921 |
GAACATTTTT |
GCCAGGTGCA |
AAAGTTCTGA |
GTGGGCAGCA |
GTTTGAACAT |
GTTTTACCTT |
GAAAGCTCAG |
GTAATTGGCA |
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2001 |
GGTGGAATTA |
GAGGGTCCTG |
GTGATGACAG |
ATGGCATTGT |
CAGCCAATCC |
CCAAGTGGGA |
GTGAGGACAT |
GTCCTGCAAT |
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2081 |
TCTGAAGGGA |
TTCTCTGTCA |
CTTGGCTCTT |
CTCTTTCATA |
TACTCAGTCA |
CTTGACTCTG |
TGATCAGAGC |
CAAATCCAGG |
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2161 |
GTTGTATGAG |
TGATGCAATG |
AGACAGAGAC |
AAAGCCCAGG |
AAATGAGTCT |
GACCGTTGAA |
TGAGAGTGTT |
TGCTAAGTCT |
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2241 |
GAGAATGACA |
AACTCCTCCC |
TCTCAGGGGC |
ACCACCACGA |
GGCGATTTGT |
GGGCCATACC |
AAGGATGTGC |
TGAGTGTGGC |
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2321 |
CTTCTCCTCT |
GACAACCGGC |
AGATTGTCTC |
TGGATCTCGA |
GATAAAACCA |
TCAAGCTATG |
GAATACCCTG |
GGTGTGTGCA |
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2401 |
AATACACTGT |
CCAGGTAAAG |
TGAGCCATCT |
CCAAGGATCT |
CTTCCACCCT |
CTTAAACTTT |
GCTTTTTTTT |
TTTTTTTTTG |
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2481 |
GCGACAGTCT |
CACTCTTGCC |
CAAGCTGGAG |
TGCAGTGGCG |
CAGTCTCGGC |
TCACTGCAAC |
CTCTGCCTCC |
CGGGCTCAAG |
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2561 |
GGATTCTGGT |
GCCTCAGTCT |
CCCGAGTAGC |
TGGTACTACA |
GGTGCGCAGC |
CACCACGCCT |
AGCTAATTTT |
TTGTGTTTTA |
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2641 |
GTAGAGACAG |
GGTTTCACCA |
TGTTGCCCAG |
GGTGGTCTCA |
AACTCCTGGG |
CTCAGGCGAT |
TTGCCTGCCT |
CGCCCTCCCA |
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2721 |
AAGTGTTGGG |
ATTACAGGCG |
TGAGCCCCCA |
CCTGCCTATC |
TTTGCCTTTT |
TTTTTTTTTT |
TCTCGGAGAC |
AGTTTCGCTT |
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2801 |
GTTCCCCAGG |
CTGAAGTACA |
ATGGCGTGAT |
CTCGGCTGAC |
CACAACCTCC |
GCCTCCTGGG |
TTCAAGCAGT |
TCTCCTGCCT |
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2881 |
CAGCCTCCCA |
AGTAGCTGGG |
ATTAGAGGCA |
TGCGCCACCA |
TGCCCGGTTT |
TGTATTTTTA |
GTAGAGACAG |
GGTTTCTCCA |
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2961 |
TGTTGGTCAG |
GCTGGTCTTG |
AACTCCCAAC |
CTCAGGTGAT |
CTGCCCGCCT |
CAGCCTCCCA |
AAGTGCTGGG |
ATTATAAGCG |
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3041 |
TGAGCCACCG |
TCCCCCGCTT |
TCTTTGCCTT |
TTTAAAGTCT |
TGTCTGGGCT |
GGGCTCACGC |
CTGTAATCCT |
AGCTCTCTGG |
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3121 |
TAGGCCAAGG |
TGGGAGGACT |
GCTTGAGGAC |
AGGAGAGCAG |
CCTGGCCAAC |
ATAGTGAGAC |
CCCATCTATT |
TAAACAAAAT |
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3201 |
TTTATTTATT |
TTTTTTCTTT |
TTTGAGATGG |
ATTCTGGGCT |
AGATCGCAGA |
TTTGGGATCG |
CAGATTGGGG |
GCTGGATCGG |
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3281 |
GGATTTGGGG |
ATGGGTGGGG |
GGCGGTGAAA |
AGGTGAAAGG |
GAGTTGCCGC |
AGCTCAGAAG |
CCGATGGTTG |
GGTGTCTGAG |
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3361 |
AAGATTACAG |
GCGTGTGCCA |
TCATGCCCAG |
CTAATTTTTG |
TATTTTTAGT |
AGAGATGGGG |
TTTCACCATG |
TTGGCCAGGC |
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3441 |
TGGTCTCAAA |
CTCCTGACCT |
CAGGTGATCC |
GCCCGCCTCA |
GCCTCCCAAA |
CTGCTGTGAT |
AACAGGCGTG |
AGTCACCGTG |
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3521 |
CCCGGCCTTA |
TCACTACTAT |
TTTGTTTTGT |
TTTGAGACAG |
TCTCATTCTG |
TCGCCCAGGC |
TGGAGTGCAG |
TAGTGCGATC |
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3601 |
TCGGCTCACT |
GCAAGCTCTG |
CTTCCCGGGT |
TCACGCCATT |
CTCCTGCCTC |
AGCCTCCCGA |
GTCGCTGGGA |
CTACAGGCGC |
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3681 |
CTGCCATCAG |
GTCTGGCTAA |
TTTTTTGTAT |
TTTTAGTAGA |
GACAGGGTTT |
CACCATGTTA |
GCCAAGATGG |
TCTTGATCTC |
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3761 |
CTGACCTCAT |
GATCCATCCA |
CCTTGGCTTC |
CTAAAGTGCT |
GGGATTACAG |
GCGTGAGCCA |
CCACACCAGG |
CCCTATTATT |
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3841 |
ATTATTATAT |
TTTTTTTGGA |
GATGAAGTTT |
CACTTGTTCG |
TTGCCCAGGC |
TGGAGTGCAA |
TGGCACAATC |
TTGGCTCATT |
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3921 |
GCACCCTTCG |
CTTCCTGGGT |
TTAAGCAGTG |
TTCCTGCCTG |
AGCCTCCCCA |
GTAGCTGGGA |
TTACAGGCAC |
CCGCCGCCAC |
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4001 |
ACCTGGTTAA |
TTTTTGTATT |
TTTGGTAGAG |
ACAGGGTTTC |
ACCATTTTGG |
CCAGGCTGGT |
CTCAAACTCC |
TGACCTCAGG |
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4081 |
TGATCCACTT |
ACCTCGCCCT |
CCCTGGGATT |
AGAGGCGTGA |
GCTTCTGCGT |
CCAGCCACCA |
TCTCTAAATT |
TTTAAAAAAT |
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4161 |
TTTCTTGTCT |
GGAATCTAAA |
GGGATTCTAT |
TGAGCTTAAC |
GGTTTGGGTT |
CTTGGTTTTT |
GAAAGGTGCT |
GCCAGCCATC |
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4241 |
ATCCTACTGA |
GGGGTAGGGC |
TGGGAGGTCT |
AGCATTTCAT |
GGGATAGGAC |
TGTTTGCCCT |
AATTTCCTTT |
CCATCTTCTG |
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4321 |
TAGGATGAGA |
GCCACTCAGA |
GTGGGTGTCT |
TGTGTCCGCT |
TCTCGCCCAA |
CAGCAGCAAC |
CCTATCATCG |
TCTCCTGTGG |
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4401 |
CTGGGACAAG |
CTGGTCAAGG |
TGAGCGTCAA |
GCCAAGGCAG |
GGGCTTTACC |
AGTCAGGGTG |
TGCTCCCAGG |
TGGTCATACA |
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4481 |
CTCCAAGTCC |
TGTGGAAAGC |
TTTGCAGATG |
CCCTCAGTTG |
ACTCTTTCTC |
TTGTCACATG |
GTCTGATGTC |
CCTTGTAAGT |
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4561 |
CAGCACACTG |
CATTGGATAT |
GTGTTATAAT |
CTAACGTGAA |
GTGGCCAGGA |
CATGTTACTG |
AATGAGAAAT |
GGCTACCGTA |
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4641 |
TCCAGAAGTG |
CCAAGCCCTT |
TTTTGTTGGG |
CCTGACCCTA |
GCTCATCAAG |
AGCTAGGATG |
TTCACCTGTC |
AACCGCACGT |
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4721 |
CTATGCAGGT |
ATGGAACCTG |
GCTAACTGCA |
AGCTGAAGAC |
CAACCACATT |
GGCCACACAG |
GCTATCTGAA |
CACGGTGACT |
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4801 |
GTCTCTCCAG |
ATGGATCCCT |
CTGTGCTTCT |
GGAGGCAAGG |
TATTTGGGGA |
CAAGGCGTCT |
CCTACTCAGT |
GGAAGACAGC |
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4881 |
GTCATGGAAG |
GAGCACTTAG |
CCAGCGTCTC |
TAACGTAAAA |
TGGCAAACAT |
TAGCCAAGAT |
GGTTTTAGGA |
GGATAATGAG |
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4961 |
ATAATGGCAA |
TCTGAGAATA |
TGTTTCCAAA |
GATTACTTTC |
AGCAAATGAC |
AGTTAAGGCA |
TACTATCTGG |
AAGAAAAAGA |
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5041 |
TGATTTTCTA |
TAAGCCTGTG |
GGTTTTTTTT |
GTTGTTTTTT |
TGTTTGTTTG |
TTTTTTGTTT |
TTTTTTTGAG |
ACGGAGTCTC |
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5121 |
ACTCGGCTGC |
CAAGGCTGGA |
GTGCAGTGGC |
GCGATCTCGG |
CTCACTGCAA |
CCATCTCCCG |
GGTTCAAGCA |
ATTCTCCCAT |
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5201 |
CTCAGCCTCC |
CGAGTAGCTA |
GGATTACAGG |
CACCCGCCAT |
CACTCCTGGG |
TAATTTTTGT |
ATGTTAGTAG |
AGAGGATTTT |
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5281 |
ACCATGTTGG |
CCAGGCTGGT |
CTTGAACTCC |
TGACCTCAGG |
TGATCCGCCC |
ACCTCGGCTT |
CCCAAAGTGC |
TGGGATTACA |
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5361 |
GGCATGAGCC |
ACCGCACCCA |
GCCTAAAGTT |
GGTTTCTTGA |
AGCAGTTGAT |
GAGATTGGGA |
TCCTGGTTTT |
CAGAAATGAT |
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5441 |
TGGAGTGATT |
TATGTAAGTT |
GGGAGGGGTT |
TTTTGATGGG |
GTTGGTAAGG |
TCTTACGTTA |
AAGGAAAGGT |
ATACAGAGAT |
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5521 |
AAATATTGGT |
ACTTGAGTCA |
TTAGCTTTCA |
AAGAAGCCTG |
GGGTAATGGA |
GGAAAGGTAA |
GAATTGATTC |
TGACAGAATC |
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5601 |
TTGAGATGGG |
CAGAATTAAC |
ATCTGGAAGA |
GGTCACAGTG |
TCCTGATTTA |
CCTTACCTGT |
GTCCAGGATG |
GCCAGGCCAT |
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5681 |
GTTATGGGAT |
CTCAACGAAG |
GCAAACACCT |
TTACACGCTA |
GATGGTGGGG |
ACATCATCAA |
CGCCCTGTGC |
TTCAGCCCTA |
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5761 |
ACCGCTACTG |
GCTGTGTGCT |
GCCACAGGCC |
CCAGCATCAA |
GATCTGGGTG |
AGTGTGGGTT |
ACAATTGACT |
GGGTACCTGG |
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5841 |
CTGCACTCTG |
AGCCCTGGCA |
ATGTTTTGGT |
TATTATATAT |
GCCATCTGAC |
TCCCACCTGG |
GAGCTAAGCT |
TTCTCAGCCT |
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5921 |
CCACGTAATG |
ACATTTTGGT |
CTGAGTAACT |
CTGTTGTGGT |
GTGCAGTCCT |
GTACATTCCA |
GGATGTTTAG |
CAGCATTTCC |
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6001 |
AGCTTCTACT |
AGATGTCAGT |
AGCAAACCAT |
CCTTCCACTA |
GTGGCAACTG |
AAAATGCATG |
TAGGCATTGA |
TACATGGACC |
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6081 |
CCAGGGAGCA |
AAATCATCCC |
TTTTTAACTT |
GAGAATCTTG |
AGGGGCTTTT |
AAGAGGAGAC |
TCTCTTGATT |
GGTAAGTCTT |
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6161 |
AAGGTTGCTT |
TTGCCCTGTT |
CCCCAGGATT |
TAGAGGGAAA |
GATCATTGTA |
GATGAACTGA |
AGCAAGAAGT |
TATCAGTACC |
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6241 |
AGCAGCAAGG |
CAGAACCACC |
CCAGTGCACC |
TCCCTGGCCT |
GGTCTGCTGA |
TGGCCAGGTA |
AGTGGGTCTG |
TCCTCTCAGG |
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6321 |
TGATTCTGCT |
TCCAGTTAAT |
TTTCTCCCTC |
TCATTCTGTT |
AGTATATCTA |
GTCTGTCAGA |
CACAAGAGCA |
GTGTCCTTGG |
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6401 |
CATAAAGTGA |
AATGACAAGC |
CAGGTTGATG |
AGGATGCCCT |
CGTTTGCCAT |
GCCAGTGAAT |
GTGTTTCTGC |
ATCAGAGGGA |
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6481 |
AGACTGATGT |
GGAACGCAGT |
GGCTGTCAGC |
CTTCAATTAA |
TACCTTAATT |
AATCTGACCA |
GTTTTCAAAT |
GTCTGGAGCC |
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6561 |
TTATCACCAG |
CTGTTTCTTC |
CTCAAGGAAT |
ACATAACCAC |
CACTTACAAG |
CTGGCTGTTG |
AAATGAGAGC |
GGTTTCTTAC |
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6641 |
AGTCTACCCG |
GCGTTGTGGC |
ACATGCCTAC |
TGGAGGCTGA |
GGTGGGAGGA |
TCTCTTGAAC |
TGCAGGGGCT |
TAAGGCTGTA |
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6721 |
GTGAGCCAGG |
ATCGCACCCC |
TGCACTCCAG |
CCTAGACAAT |
GGAGCAAGGT |
GGACGGATCT |
CAAAAAAAGC |
CACTTGGGCT |
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6801 |
GAATCTAGTG |
AGACTGCAGA |
ATTTATGCCA |
GCCTGACCTG |
TCACTGTCAT |
TTCTTCCCTG |
CAGACTCTGT |
TTGCTGGCTA |
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6881 |
CACGGACAAC |
CTGGTGCGAG |
TGTGGCAGGT |
GACCATTGGC |
ACACGCTAGA |
AGTTTATGGC |
AGAGCTTTAC |
AAATAAAAAA |
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6961 |
AAAACTGGCT |
TTTCTGACT |
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>ref|Gene_ID:10399|GNB2L1|NC_000005.9:180663927...180670905 (-)
TCTCTTTCACTGCAAGGCGGCGGCAGGAGAGGTTGTGGTGCTAGTTTCTCTAAGCCATCCAGTGCCATCCTCGTCGCTGC
AGCGACACACGCTCTCGCCGCCGCCATGACTGAGCAGATGACCCTTCGTGGCACCCTCAAGGGCCACAACGGCTGGGTAA
CCCAGATCGCTACTACCCCGCAGTTCCCGGACATGATCCTCTCCGCCTCTCGAGGTACGGACTAAGGTAGATTTCAGGAC
CCGAGATTGCAGGGCTGGGGGATTCCGCGTGTCGTGTAGGGAATTCCGCGTGTGGTGTGGCAGGCCGGTGGCGCGCGAGT
TGGCGGGGACTGACAGACTTCTCTGCCCCATTGTGAATTGGGGCGTGCGGACCCGAGCCTAGGCCTCAACCCGGGCGAAC
CACATTGCAGATGAGAACCTACGTGTACATCAGCTCGCAGCTGCTAGGAGGGTTGGAGAGTTGGAAACTTTTAAAATATC
TTTTGCCTTCTCCTTCGTAGTGTGGCCGGGGGCCTACGGGCCGGGCGGGGCGGTGATGACCCCAACATGCCATCTGAGTG
TCGGTGCTGAAATCCAGAGGCTGTTTCTGAGCTGCCGCCCGGCCCAAGGCTCGTGGGGAGGCAGGTGGACTCCAGAGGAC
CTCGTGGCTCAAGTGTCGGCCTACTTTTTCTGCCCCTGGTTCTCCCCGTCCCTATCCCTGTGTTCCTGACTGCGTTTAGA
CGCTTCTTGTGCTTCCGCTTTGCTGCTACACTGTTAAGAATTGTCTGACTTTTGAATCATGTCTGGCTGTTAATCGTAAA
ATTTGTTGAGTGGGACAGGTTTCAGTAAAAGCATCCAATCCTGTAGCGCCTGAAGTGGCTTTTCCAGCATTCATTACTAC
ATTTCTGTCGGCCCTCAGAGGTAGGCATAGGAGGCCCCAGCTACTCTACAGCCACAAACTGCTGTGCATTTGGTTGCAGA
GAAGACACAAAGTGGCTGTTGAGTTCGTCTGAGTTTCAGGAAAGGGTGTCTGTATTTCTGGCACCTAAATTAAGTTCTCA
GGATACAGGCTGGGCGCGGTGGCTCACGCCTATAATCCCAGCACTTTGGAAGGCAGAGGCGAGTGGATCACTTGAGATCA
GGAGTTAGAGACTAGCCTGGCCAATGGTGAAACCGCATCTCTAGTTAAAAAATTAGCCAGACGTGCTGGCAGGTGCCAGC
TGGCCAAGTAATCCCAGCTACTTGGGAGGCTGAGGCGGGAGAATTGCTTGAACACGGGAGGTGGAGTTTGGAGTGAGCCG
AGATCATGCCACTGCACTCCAGCCTGGGCGACAGAGCGAGACTCCATCTCAAGAAAAAAAAAAGTTATCAGGGTACAGTT
TACCTCTACGTGCGTTTTTAGTCTGGAATAGAGCCACTCAGTCCTGGTCTGTAACTGCTCTTGTCTGTTGTTTCCATCCC
TCCTTAAGCGTCCTTAGTTGTTGTTAACCCACTCATGACCTTGACACTTAGTGAATTATCCAGTGTGTTAAACGGGCTGC
GGGTTCCTCACTGATTTTTCTTCTGTTTTACCTCCTTTAGATAAGACCATCATCATGTGGAAACTGACCAGGGATGAGAC
CAACTATGGAATTCCACAGCGTGCTCTGCGGGGTCACTCCCACTTTGTTAGTGATGTGGTTATCTCCTCAGATGGCCAGT
TTGCCCTCTCAGGCTCCTGGGATGGAACCCTGCGCCTCTGGGATCTCACAACGCAAGTAGCTGCTCACTTAGCTCTGGGG
CCTTGGGAAGAATCTGGGCAGAAGTGAGGTGGATGCAATTGGCTGGTTTCCCAGGGGAGATCCAGTCCATTTGGGAACTG
GAAAGCAGAGCACACCTACAGAAGATGTTTGGCCTCCCTCACTTTAAATAAGTTACTCAGCATTGCTGAGGAGTGTGGCT
GAACATTTTTGCCAGGTGCAAAAGTTCTGAGTGGGCAGCAGTTTGAACATGTTTTACCTTGAAAGCTCAGGTAATTGGCA
GGTGGAATTAGAGGGTCCTGGTGATGACAGATGGCATTGTCAGCCAATCCCCAAGTGGGAGTGAGGACATGTCCTGCAAT
TCTGAAGGGATTCTCTGTCACTTGGCTCTTCTCTTTCATATACTCAGTCACTTGACTCTGTGATCAGAGCCAAATCCAGG
GTTGTATGAGTGATGCAATGAGACAGAGACAAAGCCCAGGAAATGAGTCTGACCGTTGAATGAGAGTGTTTGCTAAGTCT
GAGAATGACAAACTCCTCCCTCTCAGGGGCACCACCACGAGGCGATTTGTGGGCCATACCAAGGATGTGCTGAGTGTGGC
CTTCTCCTCTGACAACCGGCAGATTGTCTCTGGATCTCGAGATAAAACCATCAAGCTATGGAATACCCTGGGTGTGTGCA
AATACACTGTCCAGGTAAAGTGAGCCATCTCCAAGGATCTCTTCCACCCTCTTAAACTTTGCTTTTTTTTTTTTTTTTTG
GCGACAGTCTCACTCTTGCCCAAGCTGGAGTGCAGTGGCGCAGTCTCGGCTCACTGCAACCTCTGCCTCCCGGGCTCAAG
GGATTCTGGTGCCTCAGTCTCCCGAGTAGCTGGTACTACAGGTGCGCAGCCACCACGCCTAGCTAATTTTTTGTGTTTTA
GTAGAGACAGGGTTTCACCATGTTGCCCAGGGTGGTCTCAAACTCCTGGGCTCAGGCGATTTGCCTGCCTCGCCCTCCCA
AAGTGTTGGGATTACAGGCGTGAGCCCCCACCTGCCTATCTTTGCCTTTTTTTTTTTTTTTCTCGGAGACAGTTTCGCTT
GTTCCCCAGGCTGAAGTACAATGGCGTGATCTCGGCTGACCACAACCTCCGCCTCCTGGGTTCAAGCAGTTCTCCTGCCT
CAGCCTCCCAAGTAGCTGGGATTAGAGGCATGCGCCACCATGCCCGGTTTTGTATTTTTAGTAGAGACAGGGTTTCTCCA
TGTTGGTCAGGCTGGTCTTGAACTCCCAACCTCAGGTGATCTGCCCGCCTCAGCCTCCCAAAGTGCTGGGATTATAAGCG
TGAGCCACCGTCCCCCGCTTTCTTTGCCTTTTTAAAGTCTTGTCTGGGCTGGGCTCACGCCTGTAATCCTAGCTCTCTGG
TAGGCCAAGGTGGGAGGACTGCTTGAGGACAGGAGAGCAGCCTGGCCAACATAGTGAGACCCCATCTATTTAAACAAAAT
TTTATTTATTTTTTTTCTTTTTTGAGATGGATTCTGGGCTAGATCGCAGATTTGGGATCGCAGATTGGGGGCTGGATCGG
GGATTTGGGGATGGGTGGGGGGCGGTGAAAAGGTGAAAGGGAGTTGCCGCAGCTCAGAAGCCGATGGTTGGGTGTCTGAG
AAGATTACAGGCGTGTGCCATCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGC
TGGTCTCAAACTCCTGACCTCAGGTGATCCGCCCGCCTCAGCCTCCCAAACTGCTGTGATAACAGGCGTGAGTCACCGTG
CCCGGCCTTATCACTACTATTTTGTTTTGTTTTGAGACAGTCTCATTCTGTCGCCCAGGCTGGAGTGCAGTAGTGCGATC
TCGGCTCACTGCAAGCTCTGCTTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTCGCTGGGACTACAGGCGC
CTGCCATCAGGTCTGGCTAATTTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTAGCCAAGATGGTCTTGATCTC
CTGACCTCATGATCCATCCACCTTGGCTTCCTAAAGTGCTGGGATTACAGGCGTGAGCCACCACACCAGGCCCTATTATT
ATTATTATATTTTTTTTGGAGATGAAGTTTCACTTGTTCGTTGCCCAGGCTGGAGTGCAATGGCACAATCTTGGCTCATT
GCACCCTTCGCTTCCTGGGTTTAAGCAGTGTTCCTGCCTGAGCCTCCCCAGTAGCTGGGATTACAGGCACCCGCCGCCAC
ACCTGGTTAATTTTTGTATTTTTGGTAGAGACAGGGTTTCACCATTTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAGG
TGATCCACTTACCTCGCCCTCCCTGGGATTAGAGGCGTGAGCTTCTGCGTCCAGCCACCATCTCTAAATTTTTAAAAAAT
TTTCTTGTCTGGAATCTAAAGGGATTCTATTGAGCTTAACGGTTTGGGTTCTTGGTTTTTGAAAGGTGCTGCCAGCCATC
ATCCTACTGAGGGGTAGGGCTGGGAGGTCTAGCATTTCATGGGATAGGACTGTTTGCCCTAATTTCCTTTCCATCTTCTG
TAGGATGAGAGCCACTCAGAGTGGGTGTCTTGTGTCCGCTTCTCGCCCAACAGCAGCAACCCTATCATCGTCTCCTGTGG
CTGGGACAAGCTGGTCAAGGTGAGCGTCAAGCCAAGGCAGGGGCTTTACCAGTCAGGGTGTGCTCCCAGGTGGTCATACA
CTCCAAGTCCTGTGGAAAGCTTTGCAGATGCCCTCAGTTGACTCTTTCTCTTGTCACATGGTCTGATGTCCCTTGTAAGT
CAGCACACTGCATTGGATATGTGTTATAATCTAACGTGAAGTGGCCAGGACATGTTACTGAATGAGAAATGGCTACCGTA
TCCAGAAGTGCCAAGCCCTTTTTTGTTGGGCCTGACCCTAGCTCATCAAGAGCTAGGATGTTCACCTGTCAACCGCACGT
CTATGCAGGTATGGAACCTGGCTAACTGCAAGCTGAAGACCAACCACATTGGCCACACAGGCTATCTGAACACGGTGACT
GTCTCTCCAGATGGATCCCTCTGTGCTTCTGGAGGCAAGGTATTTGGGGACAAGGCGTCTCCTACTCAGTGGAAGACAGC
GTCATGGAAGGAGCACTTAGCCAGCGTCTCTAACGTAAAATGGCAAACATTAGCCAAGATGGTTTTAGGAGGATAATGAG
ATAATGGCAATCTGAGAATATGTTTCCAAAGATTACTTTCAGCAAATGACAGTTAAGGCATACTATCTGGAAGAAAAAGA
TGATTTTCTATAAGCCTGTGGGTTTTTTTTGTTGTTTTTTTGTTTGTTTGTTTTTTGTTTTTTTTTTGAGACGGAGTCTC
ACTCGGCTGCCAAGGCTGGAGTGCAGTGGCGCGATCTCGGCTCACTGCAACCATCTCCCGGGTTCAAGCAATTCTCCCAT
CTCAGCCTCCCGAGTAGCTAGGATTACAGGCACCCGCCATCACTCCTGGGTAATTTTTGTATGTTAGTAGAGAGGATTTT
ACCATGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCAGGTGATCCGCCCACCTCGGCTTCCCAAAGTGCTGGGATTACA
GGCATGAGCCACCGCACCCAGCCTAAAGTTGGTTTCTTGAAGCAGTTGATGAGATTGGGATCCTGGTTTTCAGAAATGAT
TGGAGTGATTTATGTAAGTTGGGAGGGGTTTTTTGATGGGGTTGGTAAGGTCTTACGTTAAAGGAAAGGTATACAGAGAT
AAATATTGGTACTTGAGTCATTAGCTTTCAAAGAAGCCTGGGGTAATGGAGGAAAGGTAAGAATTGATTCTGACAGAATC
TTGAGATGGGCAGAATTAACATCTGGAAGAGGTCACAGTGTCCTGATTTACCTTACCTGTGTCCAGGATGGCCAGGCCAT
GTTATGGGATCTCAACGAAGGCAAACACCTTTACACGCTAGATGGTGGGGACATCATCAACGCCCTGTGCTTCAGCCCTA
ACCGCTACTGGCTGTGTGCTGCCACAGGCCCCAGCATCAAGATCTGGGTGAGTGTGGGTTACAATTGACTGGGTACCTGG
CTGCACTCTGAGCCCTGGCAATGTTTTGGTTATTATATATGCCATCTGACTCCCACCTGGGAGCTAAGCTTTCTCAGCCT
CCACGTAATGACATTTTGGTCTGAGTAACTCTGTTGTGGTGTGCAGTCCTGTACATTCCAGGATGTTTAGCAGCATTTCC
AGCTTCTACTAGATGTCAGTAGCAAACCATCCTTCCACTAGTGGCAACTGAAAATGCATGTAGGCATTGATACATGGACC
CCAGGGAGCAAAATCATCCCTTTTTAACTTGAGAATCTTGAGGGGCTTTTAAGAGGAGACTCTCTTGATTGGTAAGTCTT
AAGGTTGCTTTTGCCCTGTTCCCCAGGATTTAGAGGGAAAGATCATTGTAGATGAACTGAAGCAAGAAGTTATCAGTACC
AGCAGCAAGGCAGAACCACCCCAGTGCACCTCCCTGGCCTGGTCTGCTGATGGCCAGGTAAGTGGGTCTGTCCTCTCAGG
TGATTCTGCTTCCAGTTAATTTTCTCCCTCTCATTCTGTTAGTATATCTAGTCTGTCAGACACAAGAGCAGTGTCCTTGG
CATAAAGTGAAATGACAAGCCAGGTTGATGAGGATGCCCTCGTTTGCCATGCCAGTGAATGTGTTTCTGCATCAGAGGGA
AGACTGATGTGGAACGCAGTGGCTGTCAGCCTTCAATTAATACCTTAATTAATCTGACCAGTTTTCAAATGTCTGGAGCC
TTATCACCAGCTGTTTCTTCCTCAAGGAATACATAACCACCACTTACAAGCTGGCTGTTGAAATGAGAGCGGTTTCTTAC
AGTCTACCCGGCGTTGTGGCACATGCCTACTGGAGGCTGAGGTGGGAGGATCTCTTGAACTGCAGGGGCTTAAGGCTGTA
GTGAGCCAGGATCGCACCCCTGCACTCCAGCCTAGACAATGGAGCAAGGTGGACGGATCTCAAAAAAAGCCACTTGGGCT
GAATCTAGTGAGACTGCAGAATTTATGCCAGCCTGACCTGTCACTGTCATTTCTTCCCTGCAGACTCTGTTTGCTGGCTA
CACGGACAACCTGGTGCGAGTGTGGCAGGTGACCATTGGCACACGCTAGAAGTTTATGGCAGAGCTTTACAAATAAAAAA
AAAACTGGCTTTTCTGACT
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Primary source |
RefSeq : NM_006098.4 (GI:83641897)
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Name |
Guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 (GNB2L1)
|
Type of transcript |
mRNA
|
Organism |
Homo sapiens
|
Length |
1125 nt
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Map |
5q35.3
|
Location |
Chromosome 5 (NC_000005.9) strand : -
180663927...180664041 | 180664608...180664718 | 180665098...180665238 | 180666066...180666176 |
180666486...180666581 | 180668491...180668638 | 180669173...180669344 | 180670691...180670905 |
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Exon(s) |
Start |
End |
Length |
is coding |
Exon 1
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1
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215
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215
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1
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Exon 2
|
216
|
387
|
172
|
1
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Exon 3
|
388
|
535
|
148
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1
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Exon 4
|
536
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631
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96
|
1
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Exon 5
|
632
|
742
|
111
|
1
|
Exon 6
|
743
|
883
|
141
|
1
|
Exon 7
|
884
|
994
|
111
|
1
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Exon 8
|
995
|
1109
|
115
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1
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Primary source |
NCBI : CCDS34324
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Nucleotide |
GNB2L1, mRNA isoform 1[NM_006098.4] : 107...1060
|
Length |
954
|
Location |
Chromosome 5 (NC_000005.9) strand : -
180663976...180664041 | 180664608...180664718 | 180665098...180665238 | 180666066...180666176 |
180666486...180666581 | 180668491...180668638 | 180669173...180669344 | 180670691...180670799 |
|
Start codon |
1
|
Translation |
NP_006089.1 |
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1 |
CTCTCTTTCA |
CTGCAAGGCG |
GCGGCAGGAG |
AGGTTGTGGT |
GCTAGTTTCT |
CTAAGCCATC |
CAGTGCCATC |
CTCGTCGCTG |
|
81 |
CAGCGACACA |
CGCTCTCGCC |
GCCGCCATGA |
CTGAGCAGAT |
GACCCTTCGT |
GGCACCCTCA |
AGGGCCACAA |
CGGCTGGGTA |
|
161 |
ACCCAGATCG |
CTACTACCCC |
GCAGTTCCCG |
GACATGATCC |
TCTCCGCCTC |
TCGAGATAAG |
ACCATCATCA |
TGTGGAAACT |
|
241 |
GACCAGGGAT |
GAGACCAACT |
ATGGAATTCC |
ACAGCGTGCT |
CTGCGGGGTC |
ACTCCCACTT |
TGTTAGTGAT |
GTGGTTATCT |
|
321 |
CCTCAGATGG |
CCAGTTTGCC |
CTCTCAGGCT |
CCTGGGATGG |
AACCCTGCGC |
CTCTGGGATC |
TCACAACGGG |
CACCACCACG |
|
401 |
AGGCGATTTG |
TGGGCCATAC |
CAAGGATGTG |
CTGAGTGTGG |
CCTTCTCCTC |
TGACAACCGG |
CAGATTGTCT |
CTGGATCTCG |
|
481 |
AGATAAAACC |
ATCAAGCTAT |
GGAATACCCT |
GGGTGTGTGC |
AAATACACTG |
TCCAGGATGA |
GAGCCACTCA |
GAGTGGGTGT |
|
561 |
CTTGTGTCCG |
CTTCTCGCCC |
AACAGCAGCA |
ACCCTATCAT |
CGTCTCCTGT |
GGCTGGGACA |
AGCTGGTCAA |
GGTATGGAAC |
|
641 |
CTGGCTAACT |
GCAAGCTGAA |
GACCAACCAC |
ATTGGCCACA |
CAGGCTATCT |
GAACACGGTG |
ACTGTCTCTC |
CAGATGGATC |
|
721 |
CCTCTGTGCT |
TCTGGAGGCA |
AGGATGGCCA |
GGCCATGTTA |
TGGGATCTCA |
ACGAAGGCAA |
ACACCTTTAC |
ACGCTAGATG |
|
801 |
GTGGGGACAT |
CATCAACGCC |
CTGTGCTTCA |
GCCCTAACCG |
CTACTGGCTG |
TGTGCTGCCA |
CAGGCCCCAG |
CATCAAGATC |
|
881 |
TGGGATTTAG |
AGGGAAAGAT |
CATTGTAGAT |
GAACTGAAGC |
AAGAAGTTAT |
CAGTACCAGC |
AGCAAGGCAG |
AACCACCCCA |
|
961 |
GTGCACCTCC |
CTGGCCTGGT |
CTGCTGATGG |
CCAGACTCTG |
TTTGCTGGCT |
ACACGGACAA |
CCTGGTGCGA |
GTGTGGCAGG |
|
1041 |
TGACCATTGG |
CACACGCTAG |
AAGTTTATGG |
CAGAGCTTTA |
CAAATAAAAA |
AAAAACTGGC |
TTTTCTGACA |
AAAAAAAAAA |
|
1121 |
AAAAA |
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>gi|83641897|ref|NM_006098.4|Guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 (GNB2L1)
CTCTCTTTCACTGCAAGGCGGCGGCAGGAGAGGTTGTGGTGCTAGTTTCTCTAAGCCATCCAGTGCCATCCTCGTCGCTG
CAGCGACACACGCTCTCGCCGCCGCCATGACTGAGCAGATGACCCTTCGTGGCACCCTCAAGGGCCACAACGGCTGGGTA
ACCCAGATCGCTACTACCCCGCAGTTCCCGGACATGATCCTCTCCGCCTCTCGAGATAAGACCATCATCATGTGGAAACT
GACCAGGGATGAGACCAACTATGGAATTCCACAGCGTGCTCTGCGGGGTCACTCCCACTTTGTTAGTGATGTGGTTATCT
CCTCAGATGGCCAGTTTGCCCTCTCAGGCTCCTGGGATGGAACCCTGCGCCTCTGGGATCTCACAACGGGCACCACCACG
AGGCGATTTGTGGGCCATACCAAGGATGTGCTGAGTGTGGCCTTCTCCTCTGACAACCGGCAGATTGTCTCTGGATCTCG
AGATAAAACCATCAAGCTATGGAATACCCTGGGTGTGTGCAAATACACTGTCCAGGATGAGAGCCACTCAGAGTGGGTGT
CTTGTGTCCGCTTCTCGCCCAACAGCAGCAACCCTATCATCGTCTCCTGTGGCTGGGACAAGCTGGTCAAGGTATGGAAC
CTGGCTAACTGCAAGCTGAAGACCAACCACATTGGCCACACAGGCTATCTGAACACGGTGACTGTCTCTCCAGATGGATC
CCTCTGTGCTTCTGGAGGCAAGGATGGCCAGGCCATGTTATGGGATCTCAACGAAGGCAAACACCTTTACACGCTAGATG
GTGGGGACATCATCAACGCCCTGTGCTTCAGCCCTAACCGCTACTGGCTGTGTGCTGCCACAGGCCCCAGCATCAAGATC
TGGGATTTAGAGGGAAAGATCATTGTAGATGAACTGAAGCAAGAAGTTATCAGTACCAGCAGCAAGGCAGAACCACCCCA
GTGCACCTCCCTGGCCTGGTCTGCTGATGGCCAGACTCTGTTTGCTGGCTACACGGACAACCTGGTGCGAGTGTGGCAGG
TGACCATTGGCACACGCTAGAAGTTTATGGCAGAGCTTTACAAATAAAAAAAAAACTGGCTTTTCTGACAAAAAAAAAAA
AAAAA
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Exon number |
1
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Length |
215 nt
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Location |
Chromosome 5 (NC_000005.9) : 180670691...180670905 (-)
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Is part of |
GNB2L1, mRNA isoform 1
(NM_006098.4)
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Sequence |
Show
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CTCTCTTTCACTGCAAGGCGGCGGCAGGAGAGGTTGTGGTGCTAGTTTCTCTAAGCCATCCAGTGCCATCCTCGTCGCTG
CAGCGACACACGCTCTCGCCGCCGCCATGACTGAGCAGATGACCCTTCGTGGCACCCTCAAGGGCCACAACGGCTGGGTA
ACCCAGATCGCTACTACCCCGCAGTTCCCGGACATGATCCTCTCCGCCTCTCGAG
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Exon number |
2
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Length |
172 nt
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Location |
Chromosome 5 (NC_000005.9) : 180669173...180669344 (-)
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Is part of |
GNB2L1, mRNA isoform 1
(NM_006098.4)
|
Sequence |
Show
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ATAAGACCATCATCATGTGGAAACTGACCAGGGATGAGACCAACTATGGAATTCCACAGCGTGCTCTGCGGGGTCACTCC
CACTTTGTTAGTGATGTGGTTATCTCCTCAGATGGCCAGTTTGCCCTCTCAGGCTCCTGGGATGGAACCCTGCGCCTCTG
GGATCTCACAAC
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Exon number |
3
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Length |
148 nt
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Location |
Chromosome 5 (NC_000005.9) : 180668491...180668638 (-)
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Is part of |
GNB2L1, mRNA isoform 1
(NM_006098.4)
|
Sequence |
Show
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GGGCACCACCACGAGGCGATTTGTGGGCCATACCAAGGATGTGCTGAGTGTGGCCTTCTCCTCTGACAACCGGCAGATTG
TCTCTGGATCTCGAGATAAAACCATCAAGCTATGGAATACCCTGGGTGTGTGCAAATACACTGTCCAG
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Exon number |
4
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Length |
96 nt
|
Location |
Chromosome 5 (NC_000005.9) : 180666486...180666581 (-)
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Is part of |
GNB2L1, mRNA isoform 1
(NM_006098.4)
|
Sequence |
Show
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GATGAGAGCCACTCAGAGTGGGTGTCTTGTGTCCGCTTCTCGCCCAACAGCAGCAACCCTATCATCGTCTCCTGTGGCTG
GGACAAGCTGGTCAAG
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Exon number |
5
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Length |
111 nt
|
Location |
Chromosome 5 (NC_000005.9) : 180666066...180666176 (-)
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Is part of |
GNB2L1, mRNA isoform 1
(NM_006098.4)
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Sequence |
Show
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GTATGGAACCTGGCTAACTGCAAGCTGAAGACCAACCACATTGGCCACACAGGCTATCTGAACACGGTGACTGTCTCTCC
AGATGGATCCCTCTGTGCTTCTGGAGGCAAG
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Exon number |
6
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Length |
141 nt
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Location |
Chromosome 5 (NC_000005.9) : 180665098...180665238 (-)
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Is part of |
GNB2L1, mRNA isoform 1
(NM_006098.4)
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Sequence |
Show
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GATGGCCAGGCCATGTTATGGGATCTCAACGAAGGCAAACACCTTTACACGCTAGATGGTGGGGACATCATCAACGCCCT
GTGCTTCAGCCCTAACCGCTACTGGCTGTGTGCTGCCACAGGCCCCAGCATCAAGATCTGG
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Exon number |
7
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Length |
111 nt
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Location |
Chromosome 5 (NC_000005.9) : 180664608...180664718 (-)
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Is part of |
GNB2L1, mRNA isoform 1
(NM_006098.4)
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Sequence |
Show
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GATTTAGAGGGAAAGATCATTGTAGATGAACTGAAGCAAGAAGTTATCAGTACCAGCAGCAAGGCAGAACCACCCCAGTG
CACCTCCCTGGCCTGGTCTGCTGATGGCCAG
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Exon number |
8
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Length |
115 nt
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Location |
Chromosome 5 (NC_000005.9) : 180663927...180664041 (-)
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Is part of |
GNB2L1, mRNA isoform 1
(NM_006098.4)
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Sequence |
Show
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ACTCTGTTTGCTGGCTACACGGACAACCTGGTGCGAGTGTGGCAGGTGACCATTGGCACACGCTAGAAGTTTATGGCAGA
GCTTTACAAATAAAAAAAAAACTGGCTTTTCTGAC
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Primary source |
Uniprot : P63244
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Name |
Guanine nucleotide-binding protein subunit beta-2-like 1
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Alternative name(s) |
Cell proliferation-inducing gene 21 protein Guanine nucleotide-binding protein subunit beta-like protein 12.3 Human lung cancer oncogene 7 protein Receptor for activated C kinase Receptor of activated protein kinase C 1
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Synonym(s) |
HLC-7 RACK1
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Organism |
Homo sapiens
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Length |
317 aa
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Protein existence |
---
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General annotation (Comments)
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top
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Domain
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The WD repeats domain 5 mediates interaction with TRIM63.
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Function
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Seems to bind protein kinase C acting as an intracellular receptor to anchor the activated PKC to the cytoskeleton. May be involved in up-regulation of the activity of kinases such as PKC via binding to KRT1. Together with KRT1 and ITGB1, serves as a platform for SRC activation or inactivation. May play an important role in the developing brain and neuronal differentiation.
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Similarity
|
Belongs to the WD repeat G protein beta family.
Contains 7 WD repeats.
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Subcellular location
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Cell membrane. Note=Located on plasma membrane of neuroblastoma NMB7 cells.
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Subunit
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Binds SLC9A3R1. Forms a ternary complex with TRIM63 and PRKCE. Interacts with HABP4, KRT1 and OTUB1.
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Cellular component
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cytoplasm [GO:0005737]
plasma membrane [GO:0005886]
neuronal cell body [GO:0043025]
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Molecular function
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receptor binding [GO:0005102]
protein phosphatase binding [GO:0019903]
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With
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Uniprot accession
|
IntAct
|
???
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Q7CHZ0
|
EBI-296739,EBI-2848020
|
???
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Q81PQ4
|
EBI-296739,EBI-2812142
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BCL2L11
|
O43521
|
EBI-296739,EBI-526406
|
???
|
Q81U22
|
EBI-296739,EBI-2814904
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Bcl2l11 (xeno)
|
O54918-1
|
EBI-296739,
|
???
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Q7CHI8
|
EBI-296739,EBI-2841801
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TSC22D4
|
Q9Y3Q8
|
EBI-296739,EBI-739485
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LRP12
|
Q9Y561
|
EBI-296739,EBI-296693
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COPS5
|
Q92905
|
EBI-296739,EBI-594661
|
IFNAR2
|
P48551
|
EBI-296739,EBI-958408
|
???
|
Q7CHU1
|
EBI-296739,EBI-2841165
|
???
|
Q8CZY2
|
EBI-296739,EBI-2847648
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DYNLL1
|
P63167
|
EBI-296739,EBI-349105
|
???
|
Q6KMS8
|
EBI-296739,EBI-2812678
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PTN
|
P21246
|
EBI-296739,EBI-473725
|
???
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Q8ZAR3
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EBI-296739,EBI-2850881
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Alternative product(s)
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top
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Feature key |
Position
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Length
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Description
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Feature identifier
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Molecule processing |
|
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Initiator methionine
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1 - 1
|
1
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Removed
|
P63244-INIT_MET-1
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Region |
|
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Repeat region
|
13 - 44
|
32
|
WD 1
|
P63244-REPEAT-WD_1
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Repeat region
|
61 - 91
|
31
|
WD 2
|
P63244-REPEAT-WD_2
|
Repeat region
|
103 - 133
|
31
|
WD 3
|
P63244-REPEAT-WD_3
|
Repeat region
|
146 - 178
|
33
|
WD 4
|
P63244-REPEAT-WD_4
|
Repeat region
|
190 - 220
|
31
|
WD 5
|
P63244-REPEAT-WD_5
|
Repeat region
|
231 - 260
|
30
|
WD 6
|
P63244-REPEAT-WD_6
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Repeat region
|
281 - 311
|
31
|
WD 7
|
P63244-REPEAT-WD_7
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Amino acid modifications |
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Modified residue
|
2 - 2
|
1
|
N-acetylthreonine
|
P63244-MOD_RES-2
|
Modified residue
|
130 - 130
|
1
|
N6-acetyllysine
|
P63244-MOD_RES-130
|
Modified residue
|
228 - 228
|
1
|
Phosphotyrosine
|
P63244-MOD_RES-228
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1 |
MTEQMTLRGT |
LKGHNGWVTQ |
IATTPQFPDM |
ILSASRDKTI |
IMWKLTRDET |
NYGIPQRALR |
GHSHFVSDVV |
ISSDGQFALS |
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81 |
GSWDGTLRLW |
DLTTGTTTRR |
FVGHTKDVLS |
VAFSSDNRQI |
VSGSRDKTIK |
LWNTLGVCKY |
TVQDESHSEW |
VSCVRFSPNS |
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161 |
SNPIIVSCGW |
DKLVKVWNLA |
NCKLKTNHIG |
HTGYLNTVTV |
SPDGSLCASG |
GKDGQAMLWD |
LNEGKHLYTL |
DGGDIINALC |
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241 |
FSPNRYWLCA |
ATGPSIKIWD |
LEGKIIVDEL |
KQEVISTSSK |
AEPPQCTSLA |
WSADGQTLFA |
GYTDNLVRVW |
QVTIGTR |
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>sp|P63244|GBLP_human Guanine nucleotide-binding protein subunit beta-2-like 1
MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALS
GSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNS
SNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALC
FSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIGTR
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Primary source |
Uniprot : D3DWS0
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Name |
Guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1, isoform CRA_a [submitted name]
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Alternative name(s) |
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Synonym(s) |
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Organism |
Homo sapiens
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Length |
317 aa
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Protein existence |
---
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General annotation (Comments)
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top
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With
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Uniprot accession
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IntAct
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Alternative product(s)
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top
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Feature key |
Position
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Length
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Description
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Feature identifier
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1 |
MTEQMTLRGT |
LKGHNGWVTQ |
IATTPQFPDM |
ILSASRDKTI |
IMWKLTRDET |
NYGIPQRALR |
GHSHFVSDVV |
ISSDGQFALS |
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81 |
GSWDGTLRLW |
DLTTGTTTRR |
FVGHTKDVLS |
VAFSSDNRQI |
VSGSRDKTIK |
LWNTLGVCKY |
TVQDESHSEW |
VSCVRFSPNS |
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161 |
SNPIIVSCGW |
DKLVKVWNLA |
NCKLKTNHIG |
HTGYLNTVTV |
SPDGSLCASG |
GKDGQAMLWD |
LNEGKHLYTL |
DGGDIINALC |
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241 |
FSPNRYWLCA |
ATGPSIKIWD |
LEGKIIVDEL |
KQEVISTSSK |
AEPPQCTSLA |
WSADGQTLFA |
GYTDNLVRVW |
QVTIGTR |
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>sp|D3DWS0|D3DWS0_human Guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1, isoform CRA_a [submitted name]
MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALS
GSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNS
SNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALC
FSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIGTR
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