(IL24) interleukin 24 [Homo sapiens]
Gene
Transcript(s)
Exon(s)
Protein(s)
Gene
 Accession  1090
 Official symbol  IL24
 Official name  interleukin 24
 Gene type  gene with protein product
 Organism  Homo sapiens
 Location  Chromosome 1 (NC_000001.10) :  207070788...207077483  (+)
 Map  1q32
 Length  6696  nt
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Alternative name(s) and Synynom(s) top
Synonyms MDA7; ST16; Mob-5; mda-7; IL10B; IL-24; FISP; C49A
Alternative name(s) IL-24 splice variant delE5; IL-24 splice variant delE3; suppression of tumorigenicity 16 (melanoma differentiation); melanoma differentiation association protein 7
External Links top
Ensembl ENSG00000162892
Entrez 11009
HGNC 11346
HPRD 04995
Comment top
Summary This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq].
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Related Articles in PubMed
Genomic Context top
Go to ensembl   www.ensembl.org
Sequence top
FASTA
1  GCTTGCCTGC AAACCTTTAC TTCTGAAATG ACTTCCACGG CTGGGACGGG AACCTTCCAC CCACAGCTAT GCCTCTGATT
81  GGTGAATGGT GAAGGTGCCT GTCTAACTTT TCTGTAAAAA GAACCAGCTG CCTCCAGGCA GCCAGCCCTC AAGCATCACT
161  TACAGGACCA GAGGTGAGCA TGGGGGATTC TTGGTTACTT TTTTTTGAAG GACTAGACCT CTGCTTTATT TGTGAAAAGG
241  GGTCAAGGTG GGGACAGCAG AAGTCAATTT TTTTGAGTGT TGATGTAGGG ACAAGACATG ACTGTGATGA GGAGCTGCTT
321  TCGCCAATTT AACACCAAGA AGAATTGAGG CTGCTTGGGA GGAAGGCCAG GAGGAACACG AGACTGAGAG ATGAATTTTC
401  AACAGAGGCT GCAAAGCCTG TGGACTTTAG CCAGGTGCGG TGGCTCACAC CTGTAATCCC AGAACTTTGG GAGGCTGAGG
481  TGGGCAGATC ATTTAAGGTC AGGAGTTCGA GACCAGCCTG GCCAACATGG TGAAACCCTG TCTCTACTAA AAATACAAAA
561  AAAAATTAGT TGGGCATGTG TTTTTGATAT TTTCAGATAC AAAAATCCCA GCTACTTGGG CGACTGAGGC ATGAGCATCA
641  CTTGAACCTG GTAGGCAGAG GTTGCAGTGA GCCGAGATCA TGCCACTGCA CTCCAGCCTG GGTGACAGAC TGAAATTCTG
721  TCAAAAAAAA AAAAAAAAAA AAAAGCCTGT GGAGTTTGAA AGAACAGAAT GAAAAGACAT TGAGGGAGAT GCTAAAGCAT
801  AGCCCCCGTC CCCCGTGACC CATAACCCAG GGGTCGCCGC CTCCCTAGCC CAGGTACCAG CAGAACCGGG TCTTCTCTGG
881  TCTTCCTCCC GGTGTAGGGG TGGGAGGCAG TTTCTTTAGG TGTCAGACCA GTGCCTGCAG TAAGAAAGGT TCTTAAATGA
961  TTGTGTAAAG AAGTACGAAA GAAAGGGAGA AAGTAAGAAA GGGAGGGAGC GAGAGAGGAA AGAAGGAAGA AAGAAAGGTA
1041  AGGAGGGAGG GAGGGAGAGA GGGAGGGAAA GGACAAAGGG CAAAGAAGGC AGGGGGAAAG AAATTCTCTG CATCAGTTAT
1121  AATAAATACA TAATGGCGTT AGGTTCCCCA GCTTGGAGGC TCTTCACTCA GTCCTTCCCA ACTGGCACTT CAGAGGAAGG
1201  CTTTAGAGAT GATTCATCTG GAAATCTGAT GCCTCTCTCT CATTTGGTTA CTAAAAAAAG TGAATTTTTA GACTCAAGAG
1281  TGAGTGGTTA GTGGAGGTGG CATAGTCTGT GTGTGACCCT GACCTGCCCT CTGTGCCCCT CCCTGGGACC AGGATTAACC
1361  CCTTGCTCCC TTGTGATGAG GAGTGAGGGA CAGCCGTCTC CTGGGGAGGA GAAAAAGACC TGCCAGCCTA TGTGTGCCTA
1441  GTGGCTTCAG GGCAGAACTT GGATAAGCAC ATGTCTAGTT CAGCTCTTTG TTTTCCTGGG TTTGGGCTCC CCAGACGTGG
1521  CACATTAGAA CCTCCCATTT CTCCACTCTT CTGGGTCAAA TTCTGACTCG CAGGTTGTAG GCTAGAGAGA ACTGCGATGG
1601  AGAAGGAGGA GGTGCAGGGC GTGTGGGTGT GGACGGGCAA GGTGGGGAAG AGCAGGTGGA CAGATGGCAA GACGAGCGGC
1681  CTTAAGTTTG AGGGGCAGAA AGACCCCTGC TTCACCCCCA CTGCACCTTA GCAAGGCTGC CGGTTTGCAA TAGTCTCAAC
1761  TTGCCCATTG GAGAGTGCTC GAGATTGGCC CGGGGAGACC CTCGGAGCAT TTTCCCAGGG CATGTAACTC TGGGTCAGAG
1841  GGCCGGCCTC ACAGGCTGCC TCCCTTTCTT TCAGCAGACC CTTCTGCCCT CCTTTGCTGG CGACAGCCTC TCAAATGCAG
1921  ATGGTTGTGC TCCCTTGCCT GGGTTTTACC CTGCTTCTCT GGAGCCAGGT ATCAGGGGCC CAGGGCCAAG AATTCCACTT
2001  TGGGCCCTGC CAAGTGAAGG GGGTTGTTCC CCAGAAACTG TGGGAAGCCT TCTGGGCTGT GAAAGACACT ATGGTGAGTA
2081  AAGTGCTGTT CTGGACCCAG TCGTGGGGGT TCCTGGGGGC AGTGGGCCAG TGGGGCGAGG GGATGCTATT TTATGATTCT
2161  GGAGTCCTTC ACAGCTTGCT AATCAGTTTC CAGTTTCCCA TATAATAACT CTGTGAGGTC AGAAGGCACC ACAAGCCCCA
2241  TTTACACATG AGGAAATTGG GGCTCAGAAA AAATGTGGGC AGCCTCGAGT GAAATAAGCA GTGCCCAAGG GAAACCATGA
2321  AGAGAGCTAG ATTCATCCAG GCTTCGTCCC GAATAGAGTC TTCGGCTCTA AATCTGAGAA CTGGAATGAG TGGCTGGGCT
2401  GTGGAGGAAG CTCCAAGGGC AAGAGGCAGC TCTAGGGTGC AGGCTGTCCT CCCTCACATC CTGCTTCCTC ACCACATGGA
2481  ATATGGAGCC AAAATCCTGC CCATAGTGGT TCTTAAAGCA GATAGGCTTA TTTCCTCCCA TCTCAAATGA CCAGAGGCAT
2561  CAAACTGCTT CCTTATCAAA TCTATGTTCA TGCTCTAAGA ATAAGAAGAA CTCCTGGGAC TCCATTTGCT CCTGGGGGGC
2641  CAAGCTTAGT CATTTTCGTG GCTGCAACCT TGTCTCCCCT CCCCATGGGC CAGCTCAGCC CAGTCCTTCC TGGGTCCTCT
2721  TTTGGTCCCT CTGGCCTTTG AGATCTCACA GACTAGATAG ATTTAGGGGT CTAGGGAAGC AGCACATATT TGCAGAGTTG
2801  GTTTCTATGC TGACCCCTAA CCTGGAGACG TCTTTTCTTT CTGTTTGCCA AGCAAGCTCA GGATAACATC ACGAGTGCCC
2881  GGCTGCTGCA GCAGGAGGTT CTGCAGAACG TCTCGGTAAT CAGACCTCGG GGACACCACC CTCTGTGGGA CGGGTCTACT
2961  GTGGGTGGGA GTGCAAGGCT TTCTTAGGGG AGGTTGATGA AAGCCCTTCA CTTCTTCCCT GGACTGACCT TACACAGGAC
3041  AGGGCCAGAC TGTGAGCCAG GGAAGTCAGT GTCTGGGGTT ATTGCTATGT GGTATGTGTG TGCAGTGGTA CTGGGAGATG
3121  GGGAAGGTGG AGGCTTGTAA ACATCTTTCT CCATTTAGCC AGAGAATTAT ATATTTCTCT TTTACTTGTG TAGGCCCAAT
3201  AGGCATCTAC TTAGGTTCAT GTCCTCTCTT CCATTTTCAT CCTTTTCTCT GGGTCCTTTT TCCTGGGTCC TCCTTTGGTC
3281  CATCTGGCCT TTGATGTCTC ATAGACTGGA TAGATTTAGG GGGTCCAGGG AAGCAGCACA TATTTGCAGA GCTGGTTTCT
3361  ATGCTGAACC CTAACCTGGA GACATCTTTT CTTTCTGTCA TGTGAGCTCA TGTGAAGTGA GCTCATGACT TAAAATAATA
3441  CCTAACAAAA GGATTCATCC TTTCTTTCAC CACAATCAGG TAGAGTATGT TATCAAGGAT GGGTCACCAT CTTCTCATCA
3521  TCCATCTAGT GGGCACAAAC CTACTGAGCC CTGAGCCCTG AAAGATGTGG CACTTCAGGA GCTTGAGGGG GCTAGAGTGC
3601  AATTGCTGTG TCCAAAGATA TTAGTTTCTC CTCATTTCTT CTGTTCTCAG TCATTTTCCA GCAAACTCTA TATCACCAAG
3681  TCCAAGTTCA AGCCCTTTTC AGGGTCCATC ACATCCCCAT AGCTGTTAAA GAGGCCATGT GGCATAGAAG AAAGAGAATA
3761  TTAAGCAGAT GGGCAGTCAG GAATCCTGGG AGCTAGGCTG TGTCTGCCAC TGATTGACTA TGTGAATCGG GCCAGGTCAT
3841  TTCTCTCCCT GGGTCTTGGT TCCTCCTCTC AAACAAAGAC CTGCTCTCCA TGGCCCCTGA AGGCTCCTAC AGATCTAAGG
3921  TTCATCATCA CCTTCTAGAA GATCCCTATC TCTGCTGTGC TTATCTTGCC TTGGGTGGCA TGTGGGTTGT TCCTTCAGGG
4001  GGTCAGGGTG GGCAGAGGCC TTGGCTCAGC AGTGACCCAG ACCTTCCCCA GGATGCTGAG AGCTGTTACC TTGTCCACAC
4081  CCTGCTGGAG TTCTACTTGA AAACTGTTTT CAAAAACTAC CACAATAGAA CAGTTGAAGT CAGGACTCTG AAGTCATTCT
4161  CTACTCTGGC CAACAACTTT GTTCTCATCG TGTCACAACT GCAACCCAGT GTGAGTAGCA CACGCTCTGG ATACTGGCAG
4241  CTCTGGGTTC AAGTCTAGGT CTGCTTCCAA TCTGCTGGGT GACCCTCTGC AAAGTCCTCC ACCTCCCTGG GCTTCAGTTT
4321  GTTATCTGTA AAATGGGGAT GATCACTCCT GCCTGGCAGG ATTGCTGCGA GAATTAAAGG AGGTAGCCCC TTTCACAAGG
4401  TGGGAGTTTG GTATTGGTTA CCTTGGGGAA TGCAGGATTC AGCCCTGGGC TCTCAGGCTT TGGGAGACCC TGTGGCATCA
4481  GCAGGAAAAC TGAGAGGGAG TTTGCATCTG CTCCTATCTA AAAATTGGCA CAACTTCTTT TCCCATGTTA TGTAGCAAGA
4561  AAATGAGATG TTTTCCATCA GAGACAGTGC ACACAGGCGG TTTCTGCTAT TCCGGAGAGC ATTCAAACAG GTAAGGCCAA
4641  GAGCTGAGAG CTTGCCCATC CAGCAGAATA GACTAGTCTG CACCATCACA CGAGGGCGCC TCAGAGACCC AATGCAGAAT
4721  GTAATGCAGG GGACACCATC AGCTTTGCTC CAAAGCCCCC TGACTTAGCA GGAGCACAGT TATATTTGCA GAAGCATCGT
4801  AAACTAAGTG GTCTTTTTTC TTCCAGTTTT CAAGTTAAAG TGCTTCTATA TTTCCCTACA AGATGATTTT ACGAAAGGAA
4881  CTTTCCCTGT GTTTTGTAGG TACTTGGGCT GGGCAACTGA AGTCAGAAGA GAGGGAGAAA GAAGGGAGAC ACCCCACCCC
4961  CACCCCCACC CCATACACAT CTGCAGTATT TTCCATGATG CTCAACTGGT CTAGTTGTGA AAAACAATTA TGGGAAATTA
5041  TTTTTGCTTT TCCAAAATTA TGACAACAAA GAAAACCCAA ATTTCATCCC CAGCCCCCCT AAAAACATAA ATGATTTCGA
5121  TCACTTTTTT TTTTTTGAGG AAGAGATGCA TCAGCTTTTA AATAAATGGT GAAGAGCAAT AACATCTGAT GGAGAGGGGC
5201  CACCTGGGCT CATTTCACCT GTGCAGTGGA TTCAGGTGGT GGGCCATATC CATCCCATAC TGCAGTTTGT GGTTGCTGTT
5281  GTTAGGGGTG CCATATGTCT TTCCCTTGTT CTTTGTCCAC TGATATTCAC TAGCCTGTTT GTCCTCACCC CTGAAGCAGA
5361  TAAACACATG TAGATGGAGG AAAAGTGACA GGCAGGTGGG TTCATCAGTG GGCTCATCCC AAAGGTGACC CATCCCTTGG
5441  ATTGGAGTCA GGTCTATTTT AGGCATGGCA GGTTGGAAGA AAGACTATTC TCATAGCTAA CATGGCTGAC CTTCAACCCT
5521  CTTTTCCCTT TAGTTGGACG TAGAAGCAGC TCTGACCAAA GCCCTTGGGG AAGTGGACAT TCTTCTGACC TGGATGCAGA
5601  AATTCTACAA GCTCTGAATG TCTAGACCAG GACCTCCCTC CCCCTGGCAC TGGTTTGTTC CCTGTGTCAT TTCAAACAGT
5681  CTCCCTTCCT ATGCTGTTCA CTGGACACTT CACGCCCTTG GCCATGGGTC CCATTCTTGG CCCAGGATTA TTGTCAAAGA
5761  AGTCATTCTT TAAGCAGCGC CAGTGACAGT CAGGGAAGGT GCCTCTGGAT GCTGTGAAGA GTCTACAGAG AAGATTCTTG
5841  TATTTATTAC AACTCTATTT AATTAATGTC AGTATTTCAA CTGAAGTTCT ATTTATTTGT GAGACTGTAA GTTACATGAA
5921  GGCAGCAGAA TATTGTGCCC CATGCTTCTT TACCCCTCAC AATCCTTGCC ACAGTGTGGG GCAGTGGATG GGTGCTTAGT
6001  AAGTACTTAA TAAACTGTGG TGCTTTTTTT GGCCTGTCTT TGGATTGTTA AAAAACAGAG AGGGATGCTT GGATGTAAAA
6081  CTGAACTTCA GAGCATGAAA ATCACACTGT CTTCTGATAT CTGCAGGGAC AGAGCATTGG GGTGGGGGTA AGGTGCATCT
6161  GTTTGAAAAG TAAACGATAA AATGTGGATT AAAGTGCCCA GCACAAAGCA GATCCTCAAT AAACATTTCA TTTCCCACCC
6241  ACACTCGCCA GCTCACCCCA TCATCCCTTT CCCTTGGTGC CCTCCTTTTT TTTTTATCCT AGTCATTCTT CCCTAATCTT
6321  CCACTTGAGT GTCAAGCTGA CCTTGCTGAT GGTGACATTG CACCTGGATG TACTATCCAA TCTGTGATGA CATTCCCTGC
6401  TAATAAAAGA CAACATAACT CAAGTCTGGC AGACTTTCTT CTCTATTTCT GGATGAATGC CCAGTGAGAC TGTGTTGTAC
6481  AGCTAGAAAA GGCCTTCTTC CCAATAGCAA GGCTGTGCAT CTAGCCTCAA GCTCTGGCTG AACTTTGTGG TCGACATCAA
6561  TCTAAAGATA CAGTGTCTGA CTATAACCTT GTTCCAAAAA CCTAGGCAAA GAGTATATGT AGGAGGTGGG ATATCACTTC
6641  CATGACATAA GTGCTATTGC AGAGCCGTGG CCACCCAGGA ACTCCTGACT GCTTTC
>ref|Gene_ID:11009|IL24|NC_000001.10:207070788...207077483 (+)
GCTTGCCTGCAAACCTTTACTTCTGAAATGACTTCCACGGCTGGGACGGGAACCTTCCACCCACAGCTATGCCTCTGATT
GGTGAATGGTGAAGGTGCCTGTCTAACTTTTCTGTAAAAAGAACCAGCTGCCTCCAGGCAGCCAGCCCTCAAGCATCACT
TACAGGACCAGAGGTGAGCATGGGGGATTCTTGGTTACTTTTTTTTGAAGGACTAGACCTCTGCTTTATTTGTGAAAAGG
GGTCAAGGTGGGGACAGCAGAAGTCAATTTTTTTGAGTGTTGATGTAGGGACAAGACATGACTGTGATGAGGAGCTGCTT
TCGCCAATTTAACACCAAGAAGAATTGAGGCTGCTTGGGAGGAAGGCCAGGAGGAACACGAGACTGAGAGATGAATTTTC
AACAGAGGCTGCAAAGCCTGTGGACTTTAGCCAGGTGCGGTGGCTCACACCTGTAATCCCAGAACTTTGGGAGGCTGAGG
TGGGCAGATCATTTAAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAA
AAAAATTAGTTGGGCATGTGTTTTTGATATTTTCAGATACAAAAATCCCAGCTACTTGGGCGACTGAGGCATGAGCATCA
CTTGAACCTGGTAGGCAGAGGTTGCAGTGAGCCGAGATCATGCCACTGCACTCCAGCCTGGGTGACAGACTGAAATTCTG
TCAAAAAAAAAAAAAAAAAAAAAAGCCTGTGGAGTTTGAAAGAACAGAATGAAAAGACATTGAGGGAGATGCTAAAGCAT
AGCCCCCGTCCCCCGTGACCCATAACCCAGGGGTCGCCGCCTCCCTAGCCCAGGTACCAGCAGAACCGGGTCTTCTCTGG
TCTTCCTCCCGGTGTAGGGGTGGGAGGCAGTTTCTTTAGGTGTCAGACCAGTGCCTGCAGTAAGAAAGGTTCTTAAATGA
TTGTGTAAAGAAGTACGAAAGAAAGGGAGAAAGTAAGAAAGGGAGGGAGCGAGAGAGGAAAGAAGGAAGAAAGAAAGGTA
AGGAGGGAGGGAGGGAGAGAGGGAGGGAAAGGACAAAGGGCAAAGAAGGCAGGGGGAAAGAAATTCTCTGCATCAGTTAT
AATAAATACATAATGGCGTTAGGTTCCCCAGCTTGGAGGCTCTTCACTCAGTCCTTCCCAACTGGCACTTCAGAGGAAGG
CTTTAGAGATGATTCATCTGGAAATCTGATGCCTCTCTCTCATTTGGTTACTAAAAAAAGTGAATTTTTAGACTCAAGAG
TGAGTGGTTAGTGGAGGTGGCATAGTCTGTGTGTGACCCTGACCTGCCCTCTGTGCCCCTCCCTGGGACCAGGATTAACC
CCTTGCTCCCTTGTGATGAGGAGTGAGGGACAGCCGTCTCCTGGGGAGGAGAAAAAGACCTGCCAGCCTATGTGTGCCTA
GTGGCTTCAGGGCAGAACTTGGATAAGCACATGTCTAGTTCAGCTCTTTGTTTTCCTGGGTTTGGGCTCCCCAGACGTGG
CACATTAGAACCTCCCATTTCTCCACTCTTCTGGGTCAAATTCTGACTCGCAGGTTGTAGGCTAGAGAGAACTGCGATGG
AGAAGGAGGAGGTGCAGGGCGTGTGGGTGTGGACGGGCAAGGTGGGGAAGAGCAGGTGGACAGATGGCAAGACGAGCGGC
CTTAAGTTTGAGGGGCAGAAAGACCCCTGCTTCACCCCCACTGCACCTTAGCAAGGCTGCCGGTTTGCAATAGTCTCAAC
TTGCCCATTGGAGAGTGCTCGAGATTGGCCCGGGGAGACCCTCGGAGCATTTTCCCAGGGCATGTAACTCTGGGTCAGAG
GGCCGGCCTCACAGGCTGCCTCCCTTTCTTTCAGCAGACCCTTCTGCCCTCCTTTGCTGGCGACAGCCTCTCAAATGCAG
ATGGTTGTGCTCCCTTGCCTGGGTTTTACCCTGCTTCTCTGGAGCCAGGTATCAGGGGCCCAGGGCCAAGAATTCCACTT
TGGGCCCTGCCAAGTGAAGGGGGTTGTTCCCCAGAAACTGTGGGAAGCCTTCTGGGCTGTGAAAGACACTATGGTGAGTA
AAGTGCTGTTCTGGACCCAGTCGTGGGGGTTCCTGGGGGCAGTGGGCCAGTGGGGCGAGGGGATGCTATTTTATGATTCT
GGAGTCCTTCACAGCTTGCTAATCAGTTTCCAGTTTCCCATATAATAACTCTGTGAGGTCAGAAGGCACCACAAGCCCCA
TTTACACATGAGGAAATTGGGGCTCAGAAAAAATGTGGGCAGCCTCGAGTGAAATAAGCAGTGCCCAAGGGAAACCATGA
AGAGAGCTAGATTCATCCAGGCTTCGTCCCGAATAGAGTCTTCGGCTCTAAATCTGAGAACTGGAATGAGTGGCTGGGCT
GTGGAGGAAGCTCCAAGGGCAAGAGGCAGCTCTAGGGTGCAGGCTGTCCTCCCTCACATCCTGCTTCCTCACCACATGGA
ATATGGAGCCAAAATCCTGCCCATAGTGGTTCTTAAAGCAGATAGGCTTATTTCCTCCCATCTCAAATGACCAGAGGCAT
CAAACTGCTTCCTTATCAAATCTATGTTCATGCTCTAAGAATAAGAAGAACTCCTGGGACTCCATTTGCTCCTGGGGGGC
CAAGCTTAGTCATTTTCGTGGCTGCAACCTTGTCTCCCCTCCCCATGGGCCAGCTCAGCCCAGTCCTTCCTGGGTCCTCT
TTTGGTCCCTCTGGCCTTTGAGATCTCACAGACTAGATAGATTTAGGGGTCTAGGGAAGCAGCACATATTTGCAGAGTTG
GTTTCTATGCTGACCCCTAACCTGGAGACGTCTTTTCTTTCTGTTTGCCAAGCAAGCTCAGGATAACATCACGAGTGCCC
GGCTGCTGCAGCAGGAGGTTCTGCAGAACGTCTCGGTAATCAGACCTCGGGGACACCACCCTCTGTGGGACGGGTCTACT
GTGGGTGGGAGTGCAAGGCTTTCTTAGGGGAGGTTGATGAAAGCCCTTCACTTCTTCCCTGGACTGACCTTACACAGGAC
AGGGCCAGACTGTGAGCCAGGGAAGTCAGTGTCTGGGGTTATTGCTATGTGGTATGTGTGTGCAGTGGTACTGGGAGATG
GGGAAGGTGGAGGCTTGTAAACATCTTTCTCCATTTAGCCAGAGAATTATATATTTCTCTTTTACTTGTGTAGGCCCAAT
AGGCATCTACTTAGGTTCATGTCCTCTCTTCCATTTTCATCCTTTTCTCTGGGTCCTTTTTCCTGGGTCCTCCTTTGGTC
CATCTGGCCTTTGATGTCTCATAGACTGGATAGATTTAGGGGGTCCAGGGAAGCAGCACATATTTGCAGAGCTGGTTTCT
ATGCTGAACCCTAACCTGGAGACATCTTTTCTTTCTGTCATGTGAGCTCATGTGAAGTGAGCTCATGACTTAAAATAATA
CCTAACAAAAGGATTCATCCTTTCTTTCACCACAATCAGGTAGAGTATGTTATCAAGGATGGGTCACCATCTTCTCATCA
TCCATCTAGTGGGCACAAACCTACTGAGCCCTGAGCCCTGAAAGATGTGGCACTTCAGGAGCTTGAGGGGGCTAGAGTGC
AATTGCTGTGTCCAAAGATATTAGTTTCTCCTCATTTCTTCTGTTCTCAGTCATTTTCCAGCAAACTCTATATCACCAAG
TCCAAGTTCAAGCCCTTTTCAGGGTCCATCACATCCCCATAGCTGTTAAAGAGGCCATGTGGCATAGAAGAAAGAGAATA
TTAAGCAGATGGGCAGTCAGGAATCCTGGGAGCTAGGCTGTGTCTGCCACTGATTGACTATGTGAATCGGGCCAGGTCAT
TTCTCTCCCTGGGTCTTGGTTCCTCCTCTCAAACAAAGACCTGCTCTCCATGGCCCCTGAAGGCTCCTACAGATCTAAGG
TTCATCATCACCTTCTAGAAGATCCCTATCTCTGCTGTGCTTATCTTGCCTTGGGTGGCATGTGGGTTGTTCCTTCAGGG
GGTCAGGGTGGGCAGAGGCCTTGGCTCAGCAGTGACCCAGACCTTCCCCAGGATGCTGAGAGCTGTTACCTTGTCCACAC
CCTGCTGGAGTTCTACTTGAAAACTGTTTTCAAAAACTACCACAATAGAACAGTTGAAGTCAGGACTCTGAAGTCATTCT
CTACTCTGGCCAACAACTTTGTTCTCATCGTGTCACAACTGCAACCCAGTGTGAGTAGCACACGCTCTGGATACTGGCAG
CTCTGGGTTCAAGTCTAGGTCTGCTTCCAATCTGCTGGGTGACCCTCTGCAAAGTCCTCCACCTCCCTGGGCTTCAGTTT
GTTATCTGTAAAATGGGGATGATCACTCCTGCCTGGCAGGATTGCTGCGAGAATTAAAGGAGGTAGCCCCTTTCACAAGG
TGGGAGTTTGGTATTGGTTACCTTGGGGAATGCAGGATTCAGCCCTGGGCTCTCAGGCTTTGGGAGACCCTGTGGCATCA
GCAGGAAAACTGAGAGGGAGTTTGCATCTGCTCCTATCTAAAAATTGGCACAACTTCTTTTCCCATGTTATGTAGCAAGA
AAATGAGATGTTTTCCATCAGAGACAGTGCACACAGGCGGTTTCTGCTATTCCGGAGAGCATTCAAACAGGTAAGGCCAA
GAGCTGAGAGCTTGCCCATCCAGCAGAATAGACTAGTCTGCACCATCACACGAGGGCGCCTCAGAGACCCAATGCAGAAT
GTAATGCAGGGGACACCATCAGCTTTGCTCCAAAGCCCCCTGACTTAGCAGGAGCACAGTTATATTTGCAGAAGCATCGT
AAACTAAGTGGTCTTTTTTCTTCCAGTTTTCAAGTTAAAGTGCTTCTATATTTCCCTACAAGATGATTTTACGAAAGGAA
CTTTCCCTGTGTTTTGTAGGTACTTGGGCTGGGCAACTGAAGTCAGAAGAGAGGGAGAAAGAAGGGAGACACCCCACCCC
CACCCCCACCCCATACACATCTGCAGTATTTTCCATGATGCTCAACTGGTCTAGTTGTGAAAAACAATTATGGGAAATTA
TTTTTGCTTTTCCAAAATTATGACAACAAAGAAAACCCAAATTTCATCCCCAGCCCCCCTAAAAACATAAATGATTTCGA
TCACTTTTTTTTTTTTGAGGAAGAGATGCATCAGCTTTTAAATAAATGGTGAAGAGCAATAACATCTGATGGAGAGGGGC
CACCTGGGCTCATTTCACCTGTGCAGTGGATTCAGGTGGTGGGCCATATCCATCCCATACTGCAGTTTGTGGTTGCTGTT
GTTAGGGGTGCCATATGTCTTTCCCTTGTTCTTTGTCCACTGATATTCACTAGCCTGTTTGTCCTCACCCCTGAAGCAGA
TAAACACATGTAGATGGAGGAAAAGTGACAGGCAGGTGGGTTCATCAGTGGGCTCATCCCAAAGGTGACCCATCCCTTGG
ATTGGAGTCAGGTCTATTTTAGGCATGGCAGGTTGGAAGAAAGACTATTCTCATAGCTAACATGGCTGACCTTCAACCCT
CTTTTCCCTTTAGTTGGACGTAGAAGCAGCTCTGACCAAAGCCCTTGGGGAAGTGGACATTCTTCTGACCTGGATGCAGA
AATTCTACAAGCTCTGAATGTCTAGACCAGGACCTCCCTCCCCCTGGCACTGGTTTGTTCCCTGTGTCATTTCAAACAGT
CTCCCTTCCTATGCTGTTCACTGGACACTTCACGCCCTTGGCCATGGGTCCCATTCTTGGCCCAGGATTATTGTCAAAGA
AGTCATTCTTTAAGCAGCGCCAGTGACAGTCAGGGAAGGTGCCTCTGGATGCTGTGAAGAGTCTACAGAGAAGATTCTTG
TATTTATTACAACTCTATTTAATTAATGTCAGTATTTCAACTGAAGTTCTATTTATTTGTGAGACTGTAAGTTACATGAA
GGCAGCAGAATATTGTGCCCCATGCTTCTTTACCCCTCACAATCCTTGCCACAGTGTGGGGCAGTGGATGGGTGCTTAGT
AAGTACTTAATAAACTGTGGTGCTTTTTTTGGCCTGTCTTTGGATTGTTAAAAAACAGAGAGGGATGCTTGGATGTAAAA
CTGAACTTCAGAGCATGAAAATCACACTGTCTTCTGATATCTGCAGGGACAGAGCATTGGGGTGGGGGTAAGGTGCATCT
GTTTGAAAAGTAAACGATAAAATGTGGATTAAAGTGCCCAGCACAAAGCAGATCCTCAATAAACATTTCATTTCCCACCC
ACACTCGCCAGCTCACCCCATCATCCCTTTCCCTTGGTGCCCTCCTTTTTTTTTTATCCTAGTCATTCTTCCCTAATCTT
CCACTTGAGTGTCAAGCTGACCTTGCTGATGGTGACATTGCACCTGGATGTACTATCCAATCTGTGATGACATTCCCTGC
TAATAAAAGACAACATAACTCAAGTCTGGCAGACTTTCTTCTCTATTTCTGGATGAATGCCCAGTGAGACTGTGTTGTAC
AGCTAGAAAAGGCCTTCTTCCCAATAGCAAGGCTGTGCATCTAGCCTCAAGCTCTGGCTGAACTTTGTGGTCGACATCAA
TCTAAAGATACAGTGTCTGACTATAACCTTGTTCCAAAAACCTAGGCAAAGAGTATATGTAGGAGGTGGGATATCACTTC
CATGACATAAGTGCTATTGCAGAGCCGTGGCCACCCAGGAACTCCTGACTGCTTTC