(WDR45) WD repeat domain 45 [Homo sapiens]
 Accession  149
 Official symbol  WDR45
 Official name  WD repeat domain 45
 Gene type  gene with protein product
 Organism  Homo sapiens
 Location  Chromosome X (NC_000023.10) :  48932091...48958058  (-)
 Map  Xp11.23
 Length  25968  nt
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Alternative name(s) and Synynom(s) top
Synonyms WIPI-4; WIPI4; WDRX1; JM5
Alternative name(s) wD repeat domain 45; WD45 repeat protein interacting with phosphoinositides 4; WD repeat domain, X-linked 1
External Links top
Ensembl ENSG00000196998
Entrez 11152
HGNC 28912
HPRD 06597
Comment top
Summary This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene has a pseudogene at chromosome 4q31.3. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity and full-length nature of some variants have not been determined.
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Genomic Context top
Go to ensembl   www.ensembl.org
Sequence top
>ref|Gene_ID:11152|WDR45|NC_000023.10:48932091...48958058 (-)