(ATG4A) ATG4 autophagy related 4 homolog A (S. cerevisiae) [Homo sapiens]
 Accession  207
 Official symbol  ATG4A
 Official name  ATG4 autophagy related 4 homolog A (S. cerevisiae)
 Gene type  gene with protein product
 Organism  Homo sapiens
 Location  Chromosome X (NC_000023.10) :  107334933...107397895  (+)
 Map  Xq22.1-q22.3
 Length  62963  nt
Run another request
Search gene by

Alternative name(s) and Synynom(s) top
Synonyms AUTL2; APG4A
Alternative name(s) aTG4 autophagy related 4 homolog A (S. cerevisiae); autophagin 2; APG4 autophagy 4 homolog A; AUT-like 2, cysteine endopeptidase; autophagy-related cysteine endopeptidase 2; AUT-like 2, cysteine endopeptidase (S. cerevisiae); APG4 autophagy 4 homolog A (S. cerevisiae)
External Links top
Ensembl ENSG00000101844
Entrez 115201
HGNC 16489
HPRD 06455
Comment top
Summary Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Transcript variants that encode distinct isoforms have been identified.
Bibliography top
Related Articles in PubMed
Genomic Context top
Go to ensembl   www.ensembl.org
Sequence top
>ref|Gene_ID:115201|ATG4A|NC_000023.10:107334933...107397895 (+)