(NKX2-3) NK2 transcription factor related, locus 3 (Drosophila) [Homo sapiens]
Gene
Transcript(s)
Exon(s)
Protein(s)
Gene
 Accession  5745
 Official symbol  NKX2-3
 Official name  NK2 transcription factor related, locus 3 (Drosophila)
 Gene type  gene with protein product
 Organism  Homo sapiens
 Location  Chromosome 10 (NC_000010.10) :  101292689...101296280  (+)
 Map  10
 Length  3592  nt
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Alternative name(s) and Synynom(s) top
Synonyms NK2.3; NKX4-3; NKX2C; NKX2.3; CSX3
Alternative name(s) nK2 transcription factor related, locus 3 (Drosophila); NK-2 homolog C; homeobox protein NKX2-3 homolog, mouse; NK2 transcription factor homolog C; NK-2 (Drosophila) homolog C
External Links top
Ensembl ENSG00000119919
Entrez 159296
HGNC 7836
HPRD 05992
Comment top
Summary NKX2C is a member of the NKX family of homeodomain-containing transcription factors, which are implicated in many aspects of cell type specification and maintenance of differentiated tissue functions. See Harvey (1996) [PubMed 8812123] for a review of the structure, regulation, function, and evolution of NK2 homeobox genes with an emphasis on their roles in heart development.[supplied by OMIM].
Bibliography top
Related Articles in PubMed
Genomic Context top
Go to ensembl   www.ensembl.org
Sequence top
FASTA
1  CAGTCCCTGC AGTGGCTGTA ACAAAACCCA GACCCCCAGG TCCCGGCCAA TGGAGGCGAT TTAGACTGGA GTGGGACCGC
81  GTCTGTCAAA AGCCCGACTC GGCAGCAGCG GCGGAGTCCA GGAGGAGAGC TGGAGCCGCC GCGCTGCCTC CCCGCCCCCG
161  CCGGGATTTA TTATTTGGAC TGGACAATTA AGTGGCCCTG ATGATGTTAC CAAGCCCGGT CACCTCCACC CCTTTCTCAG
241  TCAAAGACAT TTTGAATCTG GAGCAGCAGC ACCAGCACTT CCATGGTGCG CACTTGCAGG CGGACTTGGA GCACCACTTC
321  CACTCTGCGC CCTGCATGCT GGCCGCCGCT GAGGGGACGC AATTTTCTGA CGGAGGGGAG GAGGACGAGG AAGACGAGGG
401  CGAGAAATTG TCCTATTTGA ACTCACTAGC CGCAGCAGAC GGCCACGGGG ATTCAGGGCT GTGTCCCCAG GGCTATGTCC
481  ACACGGTCCT GCGAGACTCG TGCAGCGAGC CCAAGGAACA TGAAGAGGAG CCCGAGGTCG TGAGGGACCG GAGCCAAAGT
561  GAGTAGAGGG GGAAAGAAAA CGCACCCGCA CACCTGGAGC AATGGCAGAG CGCACACAAA CAGCCCACAG ACCTTGCCAG
641  CGCAGCTGCC CATCCCTTTA CCCTTTGGCT GGGGCCATGC CTCCGCCCTG GTCACCGACA GCTCCACAAA GCGCAGGTAC
721  CTGCAAGGGA GCCGGGGTGG AGAGACAAGG ACGAGGTGAC CCTGACAACT ACTCCCCCCA AAAGGGGGAA ATGAGGGAAG
801  GGAAGGTGGT TACTGCTGCC CTGATGCTGA GAGGCGACGT GGGCTCAGCG CCTGGGTCCT CATAACTGGC AGTATTTTTG
881  CTCTTCCCCC CGCCCCAAAA GGCTCTTCCC CCAAAAAGGG CAGGAGCCTG GACCTTTTTC GTTTTCCCTC TAGGGTGAGA
961  TGAGTTCTCT TAGCCCAGGG CAGCCACCCC TTCTTCTCCG AAAAGACAGC CCAAGCAGCC TGTGTCTCTC GCACCCGCAG
1041  GGGCAGGAAC TTTGGTGGAG GCCAGCTGGG CGGTTTCCTC CCTTCTCTGC TTGGAGCTCA GCGTCCTTGA ACCCGTGGCA
1121  CTCGGTAGAG AGAGAGGAGA TGATCGGAAA GTGCGTGGGA ACAATGTCTA TTCCGCGCGA CCATAGCTCT CACATCCCTA
1201  AGGCGCCAGC CTTTTTTGAA AATCCGTAAC GTTTTGCTTT GTGTCCCAGG CTGCGGGCCT AATAGAAAAC GCGCCGAACT
1281  TGAGTCCGAG ATCTTGGCTG CTCACATCGG ATGGGAAGTG AATTGATAGG GAGATGGGAT AATCAAATAA AGTCCCCAAG
1361  GAAGTGTATT TAAGAGGACA GAATCACAGT CTTTCCCCAA GAGGCGGTTT GATGTGGCAG AGGCCAAGGC CTATGCTCTC
1441  ATAGTTCCCA GAGCCGAAAA TCGGCATGAA ACTGTCTATA ACTAGTCAAT CAAACTTCAT TTTCAAAGTG CACACAGATG
1521  TCGTCATAAC ATTCGCTTGT AGTCTTTTAT AAGCCACACA CACACACAAG TCCCTGAGCC ATGCACAAGC GTTACACTCA
1601  GAACAGATTT TCGCGCAACC CATGCCCACC GGCCCACTCA TACCAACACG CCTCACACCT TCAGTTATCC TTGGTGGAGT
1681  AGAATGCAAA CGAGTTTGCA AATACTGTAG TTATTATGTA GTTGCAAGCC TTCATCCTGA AAATAGTCAT TAGCACGTCG
1761  AGCCGCATAT TTAATACAGA GTAATCTCTT CTCTCGCAGA TGCTCAAGAT CCAAATAAAC ACGCACTAAC TACCCCTCTC
1841  CACGAAACGC GCCTCCGCCT GCTAAGGGCG TTCTTTGGGT ACTGGGGCTG TCTCAGGGTC CCACAGCGCC AGGAGCCACA
1921  AACGTTCCCA AAAGTCCAGC CATTTACTAC CGCACGCTCT GCGCAGCCAC CAAAAAGGGT CACGGTGCTC CAGGACAGGA
2001  GCCGCGGTGC GGCCGGGAAC AGCTAAGGAC GCTGTTGTTT GCTTCTTCCG CAGAAAGCTG CCAGCTGAAG AAGTCTCTAG
2081  AGACGGCCGG AGACTGCAAG GCGGCGGAGG AGAGCGAGAG GCCGAAGCCA CGCAGCCGCC GGAAGCCCCG GGTCCTCTTC
2161  TCGCAAGCCC AGGTCTTCGA GCTGGAACGC AGGTTCAAGC AGCAGCGGTA CCTGTCGGCA CCCGAGCGCG AGCACCTCGC
2241  CAGCAGCCTG AAGCTCACAT CCACTCAGGT GAAAATCTGG TTCCAGAATC GCAGGTACAA GTGCAAGAGA CAGCGGCAGG
2321  ACAAGTCTCT GGAGCTTGGC GCACACGCGC CCCCGCCGCC GCCGCGCCGC GTGGCTGTCC CGGTGCTGGT GCGGGACGGC
2401  AAGCCGTGCG TCACGCCCAG CGCGCAGGCC TACGGCGCGC CCTACAGCGT GGGCGCCAGC GCCTACTCCT ACAACAGCTT
2481  CCCCGCCTAC GGCTATGGGA ACTCGGCCGC GGCCGCCGCC GCCGCCGCCG CCGCCGCCGC AGCAGCGGCG GCCTACAGCA
2561  GCAGCTATGG CTGTGCGTAC CCGGCGGGCG GCGGCGGCGG CGGCGGCGGG ACCTCCGCGG CGACCACTGC CATGCAGCCC
2641  GCCTGCAGCG CGGCCGGAGG CGGCCCCTTT GTGAACGTGA GCAACCTAGG AGGCTTCGGC AGCGGCGGCA GCGCACAGCC
2721  GTTGCACCAG GGTACTGCAG CCGGGGCCGC GTGCGCTCAG GGCACCTTGC AGGGCATCCG GGCCTGGTAG GGACGGGGCG
2801  GGTCACGCGG CGGGCACCCC AGCGCAGCCT GGCGCCGCGG GACTGAAGCT CGAGAAGGGC CTGACCTAAA GGTCAGGTCC
2881  CCTCGTTAAA AAAATATGTA CGTCTAGCTC CTCAGGGCTT CGGATCGCAG CTCACTCGAG GCCTGGGGAA GGGGACTCAG
2961  GGGCGAGGAG GATGACTGGG TCCGGTCGCC AGGACTGTCT CTGAGGCAGA AACGCCGGCT GGGCGCCGGG GAGGACGATG
3041  GCCCCGACCC TGGCAGCGAG AGGAGACCAG GAGGCTAGGA CCCTGGCCGC GCTTGGTTCT TCCAAAGCGA GAAGGGCTTC
3121  TCTCCCTCTG CCTTTCCGCG GCCTCCGCGA AGCGTTGGCG GGGAGCCCAA GGACATAACA AATTAAAAGC ATGAAGGAGA
3201  GAAAAATGGG GGTCGTGGCT TGAGAAATTC CAGGCCCTAC CGATCCTCTG CCCCCTTTGC GGGCCTGGAG CGCCATAGCA
3281  CAGTCGATTT CGTTTCGCAG CTGTCTCCCC TCCGCAGCAG ATACCTCGGT CCAGATCTCC GGATTGTCGG GGGACGCAGG
3361  ACTCTTCGAG GAAAACCAGC CGAATGAGAT CAAAAGTTGG GGGTGGGGGG AGGCTGAACA AACTCAGGAC CTGGTGGCCC
3441  ACCGGAGGTG TTACCGGGTT TCCTTTCTGT TTCGTATTCT GTATTCAGCA CATGTTATCT ATCTATCTAT CTATATAACT
3521  ATAACCACAC GCCGTGTAGA CACCCGCTGC CACACACTAC AGGAGTCAAT AAACAAGGTG CAATATTTTC AA
>ref|Gene_ID:159296|NKX2-3|NC_000010.10:101292689...101296280 (+)
CAGTCCCTGCAGTGGCTGTAACAAAACCCAGACCCCCAGGTCCCGGCCAATGGAGGCGATTTAGACTGGAGTGGGACCGC
GTCTGTCAAAAGCCCGACTCGGCAGCAGCGGCGGAGTCCAGGAGGAGAGCTGGAGCCGCCGCGCTGCCTCCCCGCCCCCG
CCGGGATTTATTATTTGGACTGGACAATTAAGTGGCCCTGATGATGTTACCAAGCCCGGTCACCTCCACCCCTTTCTCAG
TCAAAGACATTTTGAATCTGGAGCAGCAGCACCAGCACTTCCATGGTGCGCACTTGCAGGCGGACTTGGAGCACCACTTC
CACTCTGCGCCCTGCATGCTGGCCGCCGCTGAGGGGACGCAATTTTCTGACGGAGGGGAGGAGGACGAGGAAGACGAGGG
CGAGAAATTGTCCTATTTGAACTCACTAGCCGCAGCAGACGGCCACGGGGATTCAGGGCTGTGTCCCCAGGGCTATGTCC
ACACGGTCCTGCGAGACTCGTGCAGCGAGCCCAAGGAACATGAAGAGGAGCCCGAGGTCGTGAGGGACCGGAGCCAAAGT
GAGTAGAGGGGGAAAGAAAACGCACCCGCACACCTGGAGCAATGGCAGAGCGCACACAAACAGCCCACAGACCTTGCCAG
CGCAGCTGCCCATCCCTTTACCCTTTGGCTGGGGCCATGCCTCCGCCCTGGTCACCGACAGCTCCACAAAGCGCAGGTAC
CTGCAAGGGAGCCGGGGTGGAGAGACAAGGACGAGGTGACCCTGACAACTACTCCCCCCAAAAGGGGGAAATGAGGGAAG
GGAAGGTGGTTACTGCTGCCCTGATGCTGAGAGGCGACGTGGGCTCAGCGCCTGGGTCCTCATAACTGGCAGTATTTTTG
CTCTTCCCCCCGCCCCAAAAGGCTCTTCCCCCAAAAAGGGCAGGAGCCTGGACCTTTTTCGTTTTCCCTCTAGGGTGAGA
TGAGTTCTCTTAGCCCAGGGCAGCCACCCCTTCTTCTCCGAAAAGACAGCCCAAGCAGCCTGTGTCTCTCGCACCCGCAG
GGGCAGGAACTTTGGTGGAGGCCAGCTGGGCGGTTTCCTCCCTTCTCTGCTTGGAGCTCAGCGTCCTTGAACCCGTGGCA
CTCGGTAGAGAGAGAGGAGATGATCGGAAAGTGCGTGGGAACAATGTCTATTCCGCGCGACCATAGCTCTCACATCCCTA
AGGCGCCAGCCTTTTTTGAAAATCCGTAACGTTTTGCTTTGTGTCCCAGGCTGCGGGCCTAATAGAAAACGCGCCGAACT
TGAGTCCGAGATCTTGGCTGCTCACATCGGATGGGAAGTGAATTGATAGGGAGATGGGATAATCAAATAAAGTCCCCAAG
GAAGTGTATTTAAGAGGACAGAATCACAGTCTTTCCCCAAGAGGCGGTTTGATGTGGCAGAGGCCAAGGCCTATGCTCTC
ATAGTTCCCAGAGCCGAAAATCGGCATGAAACTGTCTATAACTAGTCAATCAAACTTCATTTTCAAAGTGCACACAGATG
TCGTCATAACATTCGCTTGTAGTCTTTTATAAGCCACACACACACACAAGTCCCTGAGCCATGCACAAGCGTTACACTCA
GAACAGATTTTCGCGCAACCCATGCCCACCGGCCCACTCATACCAACACGCCTCACACCTTCAGTTATCCTTGGTGGAGT
AGAATGCAAACGAGTTTGCAAATACTGTAGTTATTATGTAGTTGCAAGCCTTCATCCTGAAAATAGTCATTAGCACGTCG
AGCCGCATATTTAATACAGAGTAATCTCTTCTCTCGCAGATGCTCAAGATCCAAATAAACACGCACTAACTACCCCTCTC
CACGAAACGCGCCTCCGCCTGCTAAGGGCGTTCTTTGGGTACTGGGGCTGTCTCAGGGTCCCACAGCGCCAGGAGCCACA
AACGTTCCCAAAAGTCCAGCCATTTACTACCGCACGCTCTGCGCAGCCACCAAAAAGGGTCACGGTGCTCCAGGACAGGA
GCCGCGGTGCGGCCGGGAACAGCTAAGGACGCTGTTGTTTGCTTCTTCCGCAGAAAGCTGCCAGCTGAAGAAGTCTCTAG
AGACGGCCGGAGACTGCAAGGCGGCGGAGGAGAGCGAGAGGCCGAAGCCACGCAGCCGCCGGAAGCCCCGGGTCCTCTTC
TCGCAAGCCCAGGTCTTCGAGCTGGAACGCAGGTTCAAGCAGCAGCGGTACCTGTCGGCACCCGAGCGCGAGCACCTCGC
CAGCAGCCTGAAGCTCACATCCACTCAGGTGAAAATCTGGTTCCAGAATCGCAGGTACAAGTGCAAGAGACAGCGGCAGG
ACAAGTCTCTGGAGCTTGGCGCACACGCGCCCCCGCCGCCGCCGCGCCGCGTGGCTGTCCCGGTGCTGGTGCGGGACGGC
AAGCCGTGCGTCACGCCCAGCGCGCAGGCCTACGGCGCGCCCTACAGCGTGGGCGCCAGCGCCTACTCCTACAACAGCTT
CCCCGCCTACGGCTATGGGAACTCGGCCGCGGCCGCCGCCGCCGCCGCCGCCGCCGCCGCAGCAGCGGCGGCCTACAGCA
GCAGCTATGGCTGTGCGTACCCGGCGGGCGGCGGCGGCGGCGGCGGCGGGACCTCCGCGGCGACCACTGCCATGCAGCCC
GCCTGCAGCGCGGCCGGAGGCGGCCCCTTTGTGAACGTGAGCAACCTAGGAGGCTTCGGCAGCGGCGGCAGCGCACAGCC
GTTGCACCAGGGTACTGCAGCCGGGGCCGCGTGCGCTCAGGGCACCTTGCAGGGCATCCGGGCCTGGTAGGGACGGGGCG
GGTCACGCGGCGGGCACCCCAGCGCAGCCTGGCGCCGCGGGACTGAAGCTCGAGAAGGGCCTGACCTAAAGGTCAGGTCC
CCTCGTTAAAAAAATATGTACGTCTAGCTCCTCAGGGCTTCGGATCGCAGCTCACTCGAGGCCTGGGGAAGGGGACTCAG
GGGCGAGGAGGATGACTGGGTCCGGTCGCCAGGACTGTCTCTGAGGCAGAAACGCCGGCTGGGCGCCGGGGAGGACGATG
GCCCCGACCCTGGCAGCGAGAGGAGACCAGGAGGCTAGGACCCTGGCCGCGCTTGGTTCTTCCAAAGCGAGAAGGGCTTC
TCTCCCTCTGCCTTTCCGCGGCCTCCGCGAAGCGTTGGCGGGGAGCCCAAGGACATAACAAATTAAAAGCATGAAGGAGA
GAAAAATGGGGGTCGTGGCTTGAGAAATTCCAGGCCCTACCGATCCTCTGCCCCCTTTGCGGGCCTGGAGCGCCATAGCA
CAGTCGATTTCGTTTCGCAGCTGTCTCCCCTCCGCAGCAGATACCTCGGTCCAGATCTCCGGATTGTCGGGGGACGCAGG
ACTCTTCGAGGAAAACCAGCCGAATGAGATCAAAAGTTGGGGGTGGGGGGAGGCTGAACAAACTCAGGACCTGGTGGCCC
ACCGGAGGTGTTACCGGGTTTCCTTTCTGTTTCGTATTCTGTATTCAGCACATGTTATCTATCTATCTATCTATATAACT
ATAACCACACGCCGTGTAGACACCCGCTGCCACACACTACAGGAGTCAATAAACAAGGTGCAATATTTTCAA