(ERBB2) v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) [Homo sapiens] |
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Gene
Transcript(s)
Exon(s)
Protein(s)
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Accession
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8922
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Official symbol
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ERBB2
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Official name
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v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
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Gene type
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gene with protein product
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Organism
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Homo sapiens
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Location
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Chromosome 17 (NC_000017.10) : 37844392...37884914 (+)
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Map
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17q11.2-q12
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Length
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40523 nt
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NM_004448.2
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ERBB2, mRNA isoform 1
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NM_001005862.1
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ERBB2, mRNA isoform 2
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Accession
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Name
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Organism
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Length
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P04626
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Receptor tyrosine-protein kinase erbB-2
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Homo sapiens
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1255 aa
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Synonyms |
TKR1; HER-2/neu; NGL; NEU; HER2; HER-2; CD340
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Alternative name(s) |
c-erb B2/neu protein; neuroblastoma/glioblastoma derived oncogene homolog; herstatin; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene homolog)
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Summary |
This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq].
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Related Articles in PubMed
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Go to ensembl
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1 |
AGTTCCCGGA |
TTTTTGTGGG |
CGCCTGCCCC |
GCCCCTCGTC |
CCCCTGCTGT |
GTCCATATAT |
CGAGGCGATA |
GGGTTAAGGG |
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81 |
AAGGCGGACG |
CCTGATGGGT |
TAATGAGCAA |
ACTGAAGTGT |
TTTCCATGAT |
CTTTTTTGAG |
GTAGGGCTGT |
TTACTGTCAC |
|
161 |
CACCCCTGTC |
GGATTTTACT |
TCCTAAACGT |
ACCTGTAACT |
ATCCACTTCT |
CTCCATCTCT |
TCTGGCACCA |
CCCTGGTTAA |
|
241 |
AGACACCATC |
ATGTGTCGCC |
AAGACAGCCG |
CAGTAGCTTC |
TTAATGGCTC |
TCCCTGCCTC |
TACTTTTGCC |
TCTTCCAACC |
|
321 |
TGCGCTCCAT |
TTTGAAAAAT |
TAAAATTTGC |
CCATATCACT |
TTTTTTTTCT |
TAAAATTATT |
TACTGGCTCC |
CAATTACCTT |
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401 |
GGGTAAAATA |
CAGTCTCCAC |
AAACCCTGCC |
TGATTTGGCC |
CCTGTCCACT |
GGTCTCCCTC |
ACTCCCTTGC |
TCCAGACCCG |
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481 |
CTTCAGAGGG |
CTATGTCCCT |
CAAGCTTCCT |
GACTGCCTGG |
CCTGGTCTGA |
ATCACTCACT |
CTTCTTTTTT |
CTTCTAGTCG |
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561 |
CAATTGAAGT |
ACCACCTCCC |
GAGGGTGATT |
GCTTCCCCAT |
GCGGGGTAGA |
ACCTTTGCTG |
TCCTGTTCAC |
CACTCTACCT |
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641 |
CCAGCACAGA |
ATTTGGCTTA |
TGGTAGGCGC |
TAACTGCGTT |
TGTTTGTTCT |
TCTGTTTAAT |
GAATGAACAG |
CATACATCAA |
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721 |
CATAAGAACT |
TGACAAATCC |
AGGGCTGTAA |
AATCATCAGT |
ATGGTTCTGC |
ACTGAGATCG |
GAGAGAAGTA |
ATATTTCTAG |
|
801 |
GAAAATTAGG |
AACCCTGGGA |
ACAGGACGCT |
TGCTTTAGTA |
TCCTCTCCCT |
GCTCACCTCC |
CCTGCACTCC |
CATCAGCACC |
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881 |
GACCCACACC |
CAATCTCATA |
GAAGCCTTGT |
AGCTAAGGAT |
CACCCTTTCT |
CCTCCCCCAC |
TCTCCTCACC |
CCTTGTCAAC |
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961 |
TTTTCTTTTT |
CGTCCTGGGG |
GTTGGAATGA |
GTAAGAAGTA |
GCCTGGGATT |
CCATTCACTC |
ACTTAACAAA |
CATTTCTGAG |
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1041 |
TCCTTAGCTC |
TAGCACCTTG |
CTAAGCAAGG |
CAAAATCTCC |
AGGAGGCACC |
ATTCACATTG |
CATTTTCTGT |
GAATGGTGCT |
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1121 |
CTGGGGAGCA |
GCATTCACAT |
TGCCTTTTCT |
GTGAATGGCA |
AATTCTTCCA |
GTTAAATATA |
ACATGAATAG |
TGTCCCCTGG |
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1201 |
AGTTGACCAC |
CCAACTGATA |
CTGACTGAGA |
AGCTGAAATG |
AACAAAACAA |
CCCCTTAGCC |
CTCCAGGAGC |
TGACCGGAAA |
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1281 |
TCCAGTGCTA |
ATACTACTTT |
GCATCTTACA |
GATTAGTTCT |
TTTACAATAC |
TGTTTTTTTT |
TCTTTTTTCA |
TTTCATTTTG |
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1361 |
TCCTTTCTGT |
GACTCTGGGA |
TGAGTCTTTT |
TATGAGGATC |
CTCATATAAA |
GATGGACATT |
TAGGATTAAA |
GAGGATGAAA |
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1441 |
TCCTGACAAA |
ATAGGGAGTC |
TCCCCTTTAG |
AAAATTCCTA |
AGTAAGGCTG |
GGGGTGGTGG |
CTCACGCCTG |
TAATCCCAGC |
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1521 |
ACTTTGGGAG |
GCCGAGGCGG |
ACGGATCACC |
TGAGGTTAGG |
AGTTTGAGAC |
CAGCCTGACC |
AACATGGAGA |
AACCCCATCT |
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1601 |
CTACTAAAAA |
TACAAAATTA |
GTTGGGTGTG |
GTGGTGCATG |
CCTGTAATCC |
CAGCTACTCA |
GGAGGCTGAG |
GCAGGAGAAT |
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1681 |
CGCTTGAACC |
CAGGGAGGCA |
GAGGTTGTGG |
TGAGCCAAGA |
TTGCGCCATC |
GCACTCCAGC |
CTGGGCAACA |
AGAGCGAAAC |
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1761 |
TCAAAAAAAA |
AAAAAAAAAG |
AAAAAGAAAA |
TTCCAATTTT |
GAAGGCCTCA |
TCCTATATTA |
TGTCAAACAT |
ACTGAAATGC |
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1841 |
AGTAACGCCC |
CACATTAAAT |
AAGATTTATA |
AATAACTATA |
CATATATATA |
ATTCAATCTA |
ATTGCTGTTA |
ATAGTTGACA |
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1921 |
TATTGCTACA |
TTTATATACA |
TTTAGTTAAA |
AAAAATTTTT |
TTTCCCAGAC |
AGCCTCTCAC |
TCTTTCACCT |
AGACTGAAGT |
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2001 |
GCAGTGGCAT |
GATCACGACT |
CACTGCAACC |
TCAACCTCCC |
AGACTCAAGT |
GATCCTTCCA |
TCTCAGCCTC |
CTGAGTAGCT |
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2081 |
GGGACTGCAG |
CATGCGCCAC |
TATGCCCTGC |
TAATTTTTTT |
AATTTTTTGT |
AGAGACACGG |
TCTTGCTATG |
TTGCCTAGAC |
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2161 |
TGGTCTCCAA |
TTCCTGGGCT |
CGAGTGATCC |
TCCCGCCTCA |
ACCTCCCAAA |
GTGCTGGGAT |
TACGGGCGTG |
AGCCATGCCA |
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2241 |
CACGGCCATA |
AAATATTAAT |
TTTCGCAGCT |
TTCTTATATT |
TTAGAACTAA |
CAATGGAAAT |
TTGTTCGGGT |
CTAAAGTATT |
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2321 |
TCAGAGGTCC |
TTGAAAACCC |
ATGCCTACAT |
ACCTGATGGA |
AAAAGCAATC |
CTAGGTTAAT |
GGTGGAAGTG |
GGAGTAGAGA |
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2401 |
CTTCTGTTCT |
GTTGACTTCT |
TGGAAGATGG |
GGTACTGTCT |
CTCTGGGACA |
GCTCTTGAGA |
ATTTCCCTGC |
CAGCACAGCC |
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2481 |
CCAGATAACA |
ATCTCTAGAT |
GGCGATTACC |
TGGCCTCTCT |
TCCCAACTTT |
CTAGCCTGGA |
GCCCCTAGTT |
CTCCCCTGAG |
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2561 |
CCTCCTTAGC |
TTGTCCTTCT |
TCCTAACTTG |
TATTTGGCTT |
CAGATGTGAT |
CCACAGTCTG |
AAAAGTCACT |
AATTCATTCC |
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2641 |
TTCAACTCAG |
GCTTATTGAG |
TCCTCCTGTG |
TATCAGCCAT |
TGTACTCATG |
GGGGAAAAAA |
AAGACAAAGC |
ATATGTTAAT |
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2721 |
AGTAGAGTGT |
GCTGGACAGG |
CACAGTGGCT |
CATGCCTGTA |
ATCCCAGCAC |
TTTGGGAGGG |
CGAGGCAGGT |
GGATCATCTG |
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2801 |
AGGTCAGGAG |
TTCGAGACCA |
GCCTGACCTA |
ACATGGAGAA |
ACTCCTGAGA |
TCGTGCCATT |
GCACTCCAGC |
CTGGGCAACA |
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2881 |
AGAGCAAAAC |
TCCGTTTCAA |
AAAAAAAAAA |
AAAAGTATAG |
TGTGCTAAAG |
GCTCAACGGC |
AAGCTGACCA |
TGTTCTTAGA |
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2961 |
TCAAAATTGG |
TAGAGAGTCT |
ACAATGTGGG |
TTCCTTATTC |
ATCAAATGTT |
TATTAAGTTT |
ACCATGTGCA |
AGTCTCTGGG |
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3041 |
AACAGAGTGA |
TGAACAAGGC |
ACTGTACTTT |
TCATGGTCAG |
AGGAGGGAAA |
CAGGCCATAA |
ACAAGTGTCA |
AACAAAAGAC |
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3121 |
TGAAGCCAGG |
TGCGGTGGCT |
CACATCTGTA |
ATCCCAGCAC |
TGTGGGAGGC |
CAAGGCAGGC |
GGATCATGAG |
ATCAGGAGAT |
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3201 |
CGAGACCATC |
CTAGCCAACA |
TGGTGAAACC |
CCATCTCTAC |
TAAAAATACA |
AAAAAATTAG |
CTGGGCATGG |
TGGCACGTGC |
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3281 |
CTGTAATCCC |
AGCTACTCCG |
GAAGCTGAGG |
CAGGAGAATT |
GCTTGAACCA |
GGGAGTTGGA |
GGTTGCAGTG |
AGCCTGGATT |
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3361 |
ATGCCACTGC |
ACTCCAGCCT |
GGTGACAGAG |
CGAGACTCCA |
TCTACATTAA |
AAAAAAAAAT |
ATATATATAT |
ATATATACAC |
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3441 |
ACACACACAC |
ACACACACAC |
ACATACCCTC |
TAACCCAGGA |
ATTTCACTCC |
TAGGTATACC |
TACATAAGCT |
CCAGTATACC |
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3521 |
TAAACAAGTG |
CAAATTTGTT |
TAAGTACAGT |
TATTTGTGGT |
AGCATTAGTC |
ATTGTTTTCA |
ATAGCAAGAA |
GAAAAAGGAA |
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3601 |
ACAACTAAAT |
GTCCATCAAT |
AGGGAATGAA |
TTATATTAAT |
GGAGGGAGAG |
CCATACAATG |
GAAGGCTGAA |
CAGAAATTAA |
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3681 |
TAGGAATGGG |
GCAGATTTGT |
AATGTACTAG |
CATGGTAAAA |
CCTTCATGAT |
AGATATAGAT |
ATAGATATAG |
ATATAGATAT |
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3761 |
AGATATATAT |
ACATATACAT |
ATACATATAC |
ATATACATAT |
ATATATATAT |
ATATATATAT |
CTCTTGTGTC |
TCAGCCTCCC |
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3841 |
GAGTAGCTGG |
GATTACAGGT |
GTGTGCCACC |
ACATCCGGCT |
AATTTTTGTA |
TTTTTTAGTA |
GAGACAGGGC |
TTCACCATGT |
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3921 |
TGGTAAGGCT |
GTCTTGAACT |
CCCGACCTCA |
GGTGATCCAC |
CTGTCTCAGC |
CTCCCAAAGT |
GCTGGGATTA |
TAGGCATGAG |
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4001 |
CCATCACACC |
TGGCCAAATA |
TTTTTGATAA |
GTATCAAGTG |
CACAGTGCAG |
AACAAAATAT |
GTGTGTGTGT |
ATGCATGTGT |
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4081 |
ATGTACACCT |
ATACACTTAT |
ATACAGTACC |
CCATGTGAAG |
AAAAATAAGG |
GTACGTGTTA |
TGCGCGTAGT |
ATTATGGTTG |
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4161 |
TTATTTTTGA |
GAATATATCT |
AGAAAGATAA |
AAAAGAAAGT |
GGAAATAGTT |
CTTGCCTCTG |
GTGGGAAGTG |
GGACTATGTG |
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4241 |
CCTGATCAAT |
AGGGAAGTAA |
GGAACACTTT |
TTTTTTTTTT |
TTTTAAACGG |
AGTTTTTGCT |
CTTGTTACCC |
AGGTTGGAGT |
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4321 |
GCAATGGCGC |
GATCTTAGCT |
CACTGCAACC |
TCTGCCTCCC |
AGGTTCAAGC |
GATTCTGCTG |
CCTCAGCCTC |
CTGAGTAGCT |
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4401 |
GGGATTATAG |
GCATGCGCCT |
CCACGCCTGG |
CTAATTTTGT |
ATTTTTAGTA |
AAGATGGGGT |
TTCTCCATGT |
TGGTCAGGCT |
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4481 |
GGTCTTGAAC |
TCCCCACCTC |
AGGTGATCCG |
TCCGCCTCAG |
CCTCCCAAAG |
TGCTAGGATT |
ACAGGCGTGA |
GCCACCGTGC |
|
4561 |
CTGGCCAGGA |
ACGCTTTTTA |
TTTTTGTACC |
TTTAAAAGTG |
TGTACCGTCT |
GTGTATATAA |
TCAGTTAAAA |
ACAAAGAAAA |
|
4641 |
GCTGAGTGTG |
GTGGCTCATG |
CCTGTAATCC |
CAGCCCTTAA |
GGAGGCCGAG |
GCCGGCGGCA |
GATCACCTGA |
GGTCAGGAGT |
|
4721 |
TCAAGACCGG |
CCTGACCAAA |
ACGGTGAAAA |
CTCATCTCTA |
CAAAAACATA |
AAAATTAGCC |
AGGCATGATG |
GCAAGTGCCT |
|
4801 |
GTAATCCCAG |
CTGGTTGGGA |
GGCTGAGGTG |
GGAGACTTGC |
TTGAACCTAG |
GAGGCAGAGA |
TTGCAGTGAG |
CCAAGACTGT |
|
4881 |
ACCACTGCAC |
TCCAGCCTGG |
GCAACAGAGC |
AAGTCTCTGT |
CTCAAAACAA |
AAACAAAAAC |
ACAAAGAAAA |
AATGTAAAAC |
|
4961 |
AATTTCATGC |
AGTAGCAAGC |
ATCGAGTTAA |
ATACAGTTGA |
CCCTTGAACA |
ACACAGGTTT |
GAATTGCACG |
GGTCCATTTA |
|
5041 |
TACTCACATT |
TCTTCCACCT |
CTGCCACCCC |
CAAAATAGCA |
AGACCAACCC |
CATCTCTTTT |
CCTTTCTCTT |
CCCCCTCCTC |
|
5121 |
AGCCTACTCA |
ATGTGAAGAT |
GATGAGGATG |
AAAACCTTTG |
TGATGATCCA |
CTTCCACTTA |
ATGAATGGTA |
AATATGTTTT |
|
5201 |
TTCTTACTTA |
TGATTTTCTT |
AGTAGCATTT |
TCTTTTCTCT |
AGCTTCCTTT |
ATTGTAAAAA |
TACAGTATAT |
AACACATATC |
|
5281 |
ACATACAAAA |
TGTGTGTAAA |
TGGACTGTTT |
GCTATTGATA |
AGTATTCTGG |
TAAACAGTAG |
ACTATTAGTT |
TTTTTTGTTT |
|
5361 |
TGTGACAAGG |
TCTCCCTCTG |
TCGCCCAGCC |
TGGAATGCCG |
TGGTGTGATC |
ATGGCTCACT |
GCAGCCAAAA |
ACTTCTGGGC |
|
5441 |
TAAAGCAATC |
CTCTACTAAA |
AATACAAAAA |
TTAGCCAGGC |
ATGGTGGTGC |
GCTTCTGTAA |
TCCCAGCTAC |
TCAGGAGGCT |
|
5521 |
GAGGCAGGAG |
AATTGCTTGA |
ACCCGGGAGG |
CAGAGGTTGC |
AGTGAGCTGA |
GATTGCACCG |
TTGCATTCCA |
GCCTGGACAA |
|
5601 |
CAGAGCGAGA |
CTCCATCTCG |
AAAATAAAAT |
AATAATAATA |
ATAATAATAA |
TAATAATAAT |
AATAATAGGG |
CTGGGTGTGG |
|
5681 |
TGGCTCATGC |
CTGTAATCCC |
AGCACTTTGG |
GAGGCCAAGG |
TGGACAGATC |
ACCTGAGGTC |
AGGAGTCTCA |
ATTAAAAAAT |
|
5761 |
AAATAGGCCG |
GGCACAGTGG |
CTCATGCCCA |
TAATCCCAGC |
ACTTTGGGAG |
GCCGAGGTGG |
GCAGATCACC |
TGAGGTCAGG |
|
5841 |
AGTTTGAGAC |
CAGCCTGGCC |
AACACGGAGA |
AACGCTGCCT |
CTATCAAAAA |
TACAAAAATT |
AGCTGGATGT |
GGTGGTGCAT |
|
5921 |
GCTATAATCC |
CAGTAATACC |
AGCTACTCGG |
AAGGCTGAGG |
CAGGAGAATC |
ACTCGAATCC |
GGGACACGGA |
GGTTGCAGTG |
|
6001 |
AGCCGACATC |
ATGCCACTGC |
GCTCCAGCCT |
GGGTGACAGT |
GAGACTCTGT |
CTCAGAAAAA |
AAAAAAAAAA |
AAAAAAAAAA |
|
6081 |
AAAAAAAAAT |
ATATATATAT |
ATATATATAT |
ATATATATAT |
ATATATATAT |
GTGTGTATAT |
ATATATATAT |
ACACATATAT |
|
6161 |
ATGTGTATAT |
ATATATACAC |
ACACACATAT |
ATATGTGTAT |
ATATAAAATA |
AAATAAATAA |
TAATAAAACA |
TTTACTTTGG |
|
6241 |
CTGCTGTTGC |
TGCGGGGAGA |
ATTGCAGGGT |
GTCAAAAGTA |
GCACTGGTGG |
AGGGGTAGTG |
ATCAAAGTCT |
GGTGCTTTAG |
|
6321 |
CCCAAAGGAG |
AAATGATAGA |
GACTCAGACT |
AGCTGGTGAT |
GGAGGTAGAA |
TAAGCATAAA |
TGTATCAAAA |
AGAGGAGTTG |
|
6401 |
ATAGATCTTA |
AAGAATGATT |
GGATTTGAAG |
GGCAAAGGAA |
GAGAAGAATC |
AACCAGGTGG |
GTTCAGTGAA |
TGAAACCATC |
|
6481 |
AGAAACGAAT |
TGTCCCCTGA |
AATCAAGACT |
TTGTGATTGC |
CATAGTTGTA |
TGCTTCTCAA |
AGGTTCCTCG |
TCTCCTCTTC |
|
6561 |
CTTGGACCAA |
AAGTCAGAGG |
CAAGAATGCC |
CTCATTCATA |
CCCCAGTGGT |
CTATACCTCC |
AGCAGCAAGT |
CGAGTGAGCA |
|
6641 |
AGTGATGTCC |
TGAAAGGCCC |
AGTGGATCAG |
TGGAATGAAG |
CGGGCAGGAA |
GACTTAGTGC |
TCCTGAAACA |
AGGAATCCAG |
|
6721 |
AATCCAGGAG |
AAGGATGGCT |
CAGTGGGGCT |
TTCAAGGGAC |
AAGTATGGGG |
GTTGAAGGGG |
TCACTGTCCC |
TATACCAAAT |
|
6801 |
CCGAAAATAT |
TGTGACCAGG |
AACCATTCTG |
TCCAACTCTT |
CTATTTCAGG |
TGGCAAAGCA |
AAGCTATATT |
CAAGACCACA |
|
6881 |
TGCAAAGCTA |
CTCCCTGAGC |
AAAGAGTCAC |
AGATAAAACG |
GGGGCACCAG |
TAGAATGGCC |
AGGACAAACG |
CAGTGCAGCA |
|
6961 |
CAGAGACTCA |
GACCCTGGCA |
GCCATGCCTG |
CGCAGGCAGT |
GATGAGAGTG |
ACATGTACTG |
TTGTGGACAT |
GCACAAAAGT |
|
7041 |
GAGGTGAGTC |
GCAGGACAGA |
AGAGTGCTTT |
TTGTTTCAGC |
AGAGCAGCCT |
GGGGAGAGAT |
AAAAGCTACT |
CCTGGGGCCT |
|
7121 |
GGGCCTGCAT |
TCCTGAGATG |
TGGGTAAGAG |
GGGCCCAGGG |
TCAGAGTGTC |
TGGCAAGCTT |
GGCTCTGCCC |
CTTTGCTGTC |
|
7201 |
CTGGAGACTA |
GGGCTAATCC |
TGGGCTCAGG |
GAGTGGCCTC |
CCCATGGTTA |
GGATACAAGT |
GCTCATCAAG |
GGCCACCCCT |
|
7281 |
AGGAAGGACC |
AATTTTCCTA |
TCAGAAGCTT |
CTAAGTTATC |
CTCCTTTGGC |
CCAAAGGGAC |
ACCTCAAGCC |
TACTCTGAGG |
|
7361 |
AACTCTTTCC |
AATGAACTAA |
TTCCTACAGT |
CACTTCCCCA |
GCAACCTGTG |
CCTCAGCCTC |
AAGGCACTGT |
GGGGTAGGCC |
|
7441 |
TCAGTTTGTG |
GCCTGGACAT |
CGGACTGTGG |
ACCAGACGAC |
TCCTCCCGAT |
TTCTGTTTGT |
TTTCAGTCCT |
CTGACCCCAA |
|
7521 |
GCTGGCTGGT |
GAAGTAGGTA |
GAGGGAGGAG |
ACTTTGGTGC |
ATGCATACAC |
ACACACACAC |
ACACACACAC |
ACACACACAC |
|
7601 |
ACACACACAC |
ACACACACAC |
GTCTCCTGTG |
CCCCCCAGTC |
TCCATGGCTG |
GTCAATGATT |
GACTGGCATT |
TCACAGGCCG |
|
7681 |
CTGGTTGCAG |
CCCCAGCCTG |
TTGACTTAGA |
GGTCACCCTC |
GGAAGCTAGA |
GCCCTGTCCT |
GCCTCTTCAG |
TGTCAGTGGT |
|
7761 |
CACTCCACTG |
CCCACAGGCT |
GGGGTCTTGG |
GCAAAACACA |
CGCATCTGCC |
CTGATCTGAG |
TTTGCTGCCC |
TCTGTCCCGC |
|
7841 |
AGTCAGCCCC |
ACTCTGTTCC |
CACTCCCTCT |
CCCCAGCCCC |
CTAGCTAGAC |
CCCTCTCACC |
AGCACCCCTT |
TCCCTTCCCT |
|
7921 |
GAGGGTCCCC |
CTCGCTGTCT |
TTGTCCCTCA |
GACATCCTCT |
TTCCTGGGCT |
CTCCTGCCAG |
GCCCTGCTGG |
AGGGACAGTT |
|
8001 |
AAGGAGGAAA |
TCGAATCAGC |
AGCGCCCACC |
CCTGCCCCCC |
TTCCTCTCCT |
CTTGTCAGAC |
ACCAGACGAG |
GTTTTTTCCT |
|
8081 |
CTGGCTTCCC |
AGCTCTGAAT |
GGGCTCATTC |
TTTTTCAGAG |
GCTCGGCCCC |
TCTCGAGCCT |
CCTCCCCAGG |
GCGTGAGTTC |
|
8161 |
TGACCCCAGC |
TCCTCCCCCC |
ATCCCCACTC |
CAGCCCCCTC |
TCCAGCTTGC |
TCCACCCTCT |
CTACCGCCCA |
CCGGGACTGG |
|
8241 |
GCATTGTCTG |
CCAGTCCGGG |
TTTCTTCCTG |
GGATTTGGGA |
TGCAGAGAGG |
ATGGGTTTGC |
TTGGGCGGGG |
GGGTGGAGAG |
|
8321 |
TGAAGGGGGG |
AAGCAGGATC |
TTTGTAGAGG |
GAGGGACCTA |
CAGTTACCTG |
GACTTCTTTC |
CTCTGTCTCC |
CCTCTTGGTA |
|
8401 |
CCCTTGACTG |
GGGCTCTTGA |
GGGTAATGGG |
TGAAGCCAAA |
TCTGCCATGG |
CTCAGTTCCC |
AGCTCAGCTC |
TGTGACCTTG |
|
8481 |
GGAAAGTTCC |
TTTAGCTCGT |
GGAATCTCAA |
GGCTCAAGGT |
TCCTCTTCTG |
CAAAATGGGG |
AATGATAACA |
CCTGCCTCCT |
|
8561 |
CTGGAGTCTT |
GGGGACTCAG |
TGTTCTGAGG |
AACGTGGCTG |
TAGGTCAGAG |
TGGCACAGAG |
TAGGGTCCAA |
TGAAGCATGG |
|
8641 |
CGTCCACAGT |
AGCTTTCCTG |
ACTGGACTAA |
CCTTTCCGGA |
CACAACAGCA |
GGGCAGGGGT |
GGGGCCTGGG |
GAGAAAGGAC |
|
8721 |
ACCTCTAACC |
CTGATCCTAA |
CATCCCGATG |
GCCTCTAAGG |
CTGCCTGCAC |
ACTCATCCAG |
GTGCAAGCCC |
TCCAAGGTGT |
|
8801 |
GGTGTGATGA |
ACCAGTGACT |
CCTGGAGCCA |
GGTCAGCGCA |
TCCTCTTCCC |
GCAGGGCTGT |
AAGCTGCAGG |
ACTGAGAGGC |
|
8881 |
AGGTTGACCA |
GGTCCTGGGC |
TGGATGATGG |
GGTGAGAGTA |
AGGGGTCAGT |
TTTGATACAT |
GCCCAACTTT |
TCTCTCTAGC |
|
8961 |
CCTAAGACAT |
CCTGGGCAAA |
TTGCTTACCT |
CAGTTCCCCT |
GATCCTCACC |
CTAACCCTAA |
CACCAGCTCA |
AGAGAAAATA |
|
9041 |
GGGATATTGA |
TGGCCATCCA |
GAAGGGCTGC |
TGTGTTCCAT |
ACACAGCAAT |
ATTTCTCGAA |
TGTTTGTGAC |
AGCGGTCCAA |
|
9121 |
GGAATAAGTT |
AATTTTACAT |
TATCACTCTG |
GATACCTGTA |
CAAAACTCCA |
CCTTATCCTT |
ACTATATGAA |
TGTGCTAGGG |
|
9201 |
TTGTTTTTTT |
GTTTTGTTTT |
TTTTTTTTTT |
TTTTGAGACA |
GAGTTTCGCT |
CTTGTTGCCC |
AGGCTGGAGT |
ACAATGGCGC |
|
9281 |
GATCTTGGCT |
CACCGCAACC |
TCCGCTTCCC |
AGGTTCAAGC |
GATTCACCTG |
CCTCAGCCTT |
CCCGAGTAGC |
TGGGATTACA |
|
9361 |
GGCATGCGCC |
ACCATGCCCG |
GCTAATTTTG |
TGTTTTTAGT |
AGAGACAGGG |
TTTCTCCATG |
TTGGTCAGGC |
TGGTACCAAA |
|
9441 |
CTCCCGACCT |
CAGGTGATCC |
ACCTGCCTTG |
GCCTCCCAAA |
GTGCTGCAAT |
TACAGGCATG |
AGCCACCGCA |
CCCAGCCGTG |
|
9521 |
CTAGGGTCTT |
TTTCTGTTCA |
ATTCCTTTCT |
CTCTCTTGCT |
CTCTTTCTTT |
CTTTCAATGG |
AGTCTTACTC |
TGTCACCCAG |
|
9601 |
GCTGGAGTGC |
AGTGGCAAGA |
TCTCAGCTCA |
CTGCAACCTC |
TGCCCTCTGA |
GTTCAAGCAA |
TTCTCCTGCC |
TCAGCCTCCC |
|
9681 |
GAGTAGCTGG |
GATTACAGGT |
GCCTGCCACC |
ACACCTAGTT |
AATTTTTGTA |
CTTTTAGTAG |
AGATGGGGTT |
TTGTCATGTT |
|
9761 |
GGCCAGGCTG |
GTCTCGAACT |
CCTGACCTCG |
TGATCTGCCT |
GTCTTGGCCT |
CCCAAAGTGC |
TGGGATTACA |
GGCATGAGCC |
|
9841 |
GCCATACTCG |
GCCAACTTTG |
TATTACTTTC |
TTAAAGAGAG |
TTTCCCAAAT |
TATATAAGCT |
TCAGGCCCCA |
CAAAACCTAG |
|
9921 |
ATCTGCCCCA |
GTATAACTAA |
ATCTGGGACC |
ATTTATTGAG |
CAATTATTAT |
GTGCCAAGTA |
TTGCGCTGAG |
TGCTTCCAGA |
|
10001 |
GCATTATCTC |
CTTTAACCCC |
AGCATAGTAT |
GTCAGATGCT |
GTTTTACAGA |
TGAGCCAACT |
GAGACCAGAG |
ATGCTCAGTC |
|
10081 |
ACTTGCCCAA |
GGTGACATGA |
CTGATATGGA |
ATAGAGTCAA |
GATTTTTTTT |
TTTTTTTTTG |
ACACGGAGTC |
TCACTCTGTC |
|
10161 |
TCCCAGGCTG |
GAGTGCAGAG |
GCGCAATCTC |
AGCTCACTGC |
AAGCTCTGCC |
TCCCAGGTTC |
ACGCCATTCT |
CCTGCCTCAG |
|
10241 |
CCTCCTGAGT |
AGCTGGGACT |
ACAGGCACCC |
GCCACCACAC |
CTGGCTAATT |
TTTTGTATTT |
TTAGCAGAGA |
CAGGGTTTCA |
|
10321 |
CCGTGTTAGC |
CAGGATGGTC |
TCGATCTCCT |
GACCTCGTGA |
TCTGCCTGCC |
TCGGCCTCCC |
AAAGTGCTGG |
AATTACAGGT |
|
10401 |
GTGAGCCACC |
GCGACTGGCC |
AGATTCAAGA |
TTTGAACCCA |
GGTCCTCTTG |
GTCCCAGAGG |
CCCCTGTTTC |
TCAACTCCCT |
|
10481 |
AGGATGGCAT |
AGCAACCTGT |
CCCACAAGAG |
GTGCCTGCTT |
TAAGTGTGCT |
CAGCACATGG |
AAGCAAGTTT |
AGAAATGCAA |
|
10561 |
GTGTATACCT |
GTAAAGAGGT |
GTGGGAGATG |
GGGGGGAGGG |
AAGAGAGAAA |
GAGATGCTGG |
TGTCCTTCAT |
TCTCCAGTCC |
|
10641 |
CTGATAGGTG |
CCTTTGATCC |
CTTCTTGACC |
AGTATAGCTG |
CATTCTTGGC |
TGGGGCATTC |
CAACTAGAAC |
TGCCAAATTT |
|
10721 |
AGCACATAAA |
AATAAGGAGG |
CCCAGTTAAA |
TTTGAATTTC |
AGATAAACAA |
TGAATAATTT |
GTTAGTATAA |
ATATGTCCCA |
|
10801 |
TGCAATATCT |
TGTTGAAATT |
AAAAAAAAAA |
AAAAAAGTCT |
TCCTTCCATC |
CCCACCCCTA |
CCACTAGGCC |
TAAGGAATAG |
|
10881 |
GGTCAGGGGC |
TCCAAATAGA |
ATGTGGTTGA |
GAAGTGGAAT |
TAAGCAGGCT |
AATAGAAGGC |
AAGGGGCAAA |
GAAGAAACCT |
|
10961 |
TGAATGCATT |
GGGTGCTGGG |
TGCCTCCTTA |
AATAAGCAAG |
AAGGGTGCAT |
TTTGAAGAAT |
TGAGATAGAA |
GTCTTTTTGG |
|
11041 |
GCTGGGTGCA |
GTTGCTCGTG |
GTTGTAATTC |
CAGCACTTTG |
GGAGGCTGAG |
GCGGGAGGAT |
CACCTGAGGT |
TGGGAGTTCA |
|
11121 |
AGACCAGCCT |
CACCAACGTG |
GAGAAACCCT |
GTCTTTACTA |
AAAATACAAA |
AAATTAGCTG |
GTCATGGTGG |
CACATGCCTG |
|
11201 |
TAATCCCAGC |
TGCTCGGGAG |
GCTGAGGCAG |
GAGAATCACT |
TGAACCAGGG |
AGGCAGAGGT |
TGTGGTGAGC |
AGAGATCGCG |
|
11281 |
CCATTGCTCT |
CCAGCCTGGG |
CAACAAGAGC |
AAAAGTTCGT |
TTAAAAAAAA |
AAAAAAGTCC |
TTTCGATGTG |
ACTGTCTCCT |
|
11361 |
CCCAAATTTG |
TAGACCCTCT |
TAAGATCATG |
CTTTTCAGAT |
ACTTCAAAGA |
TTCCAGAAGA |
TATGCCCCGG |
GGGTCCTGGA |
|
11441 |
AGCCACAAGG |
TAAACACAAC |
ACATCCCCCT |
CCTTGACTAT |
CAATTTTACT |
AGAGGATGTG |
GTGGGAAAAC |
CATTATTTGA |
|
11521 |
TATTAAAACA |
AATAGGCTTG |
GGATGGAGTA |
GGATGCAAGC |
TCCCCAGGAA |
AGTTTAAGAT |
AAAACCTGAG |
ACTTAAAAGG |
|
11601 |
GTGTTAAGAG |
TGGCAGCCTA |
GGGAATTTAT |
CCCGGACTCC |
GGGGGAGGGG |
GCAGAGTCAC |
CAGCCTCTGC |
ATTTAGGGAT |
|
11681 |
TCTCCGAGGA |
AAAGTGTGAG |
AACGGCTGCA |
GGCAACCCAG |
GCGTCCCGGC |
GCTAGGAGGG |
ACGCACCCAG |
GCCTGCGCGA |
|
11761 |
AGAGAGGGAG |
AAAGTGAAGC |
TGGGAGTTGC |
CACTCCCAGA |
CTTGTTGGAA |
TGCAGTTGGA |
GGGGGCGAGC |
TGGGAGCGCG |
|
11841 |
CTTGCTCCCA |
ATCACAGGAG |
AAGGAGGAGG |
TGGAGGAGGA |
GGGCTGCTTG |
AGGAAGTATA |
AGAATGAAGT |
TGTGAAGCTG |
|
11921 |
AGATTCCCCT |
CCATTGGGAC |
CGGAGAAACC |
AGGGGAGCCC |
CCCGGGCAGC |
CGCGCGCCCC |
TTCCCACGGG |
GCCCTTTACT |
|
12001 |
GCGCCGCGCG |
CCCGGCCCCC |
ACCCCTCGCA |
GCACCCCGCG |
CCCCGCGCCC |
TCCCAGCCGG |
GTCCAGCCGG |
AGCCATGGGG |
|
12081 |
CCGGAGCCGC |
AGTGAGCACC |
ATGGAGCTGG |
CGGCCTTGTG |
CCGCTGGGGG |
CTCCTCCTCG |
CCCTCTTGCC |
CCCCGGAGCC |
|
12161 |
GCGAGCACCC |
AAGGTGGGTC |
TGGTGTGGGG |
AGGGGACGGA |
GCAGCGGCGG |
GACCCTGCCC |
TGTGGATGCC |
CCGCCGAGGT |
|
12241 |
CCCGCGGCCG |
GCGGGGCCAG |
AGGGGCCCGG |
ACGAGCTCTC |
CTATCCCGAA |
GTTGTGGACA |
GTCGAGACGC |
TCAGGGCAGC |
|
12321 |
CGGGCCCTGG |
GGCCCTCGGG |
CGGGAGGGGG |
CAGTTACACG |
GCAGCGGCTC |
GAGATGGCCC |
ATCCAAGAGA |
CTGGCGCTTT |
|
12401 |
CCAGGCTCCG |
AGGGGCTCCG |
GGAACTTGTC |
AAAGAAGTTC |
TCTGAAATTG |
TTCAGAAAGT |
TTTCCCGCAA |
AGGGTGTATT |
|
12481 |
GCGTAGAGCG |
CGCGCGCGCG |
TTTCCCCCCT |
TCTTGAGCCC |
CCTCAAGCTT |
TCTCAAAGCC |
TTTCCAGTTG |
GCAGCCTCCG |
|
12561 |
CCTCCGGACT |
GGCCTGGGCT |
GGATTCCTTG |
GGGGGGTCCT |
CTGCCCTGCC |
CCTCCTCCAG |
CCCCTCCCCG |
CTCCCCTTCA |
|
12641 |
GACGATTTTG |
GTTTGGTTGC |
TCCTGCTTCT |
GGCGGGGTCG |
GGTGTGTGTG |
TGTGTGGTGG |
AGTGGAGGGT |
GGCATAGCAA |
|
12721 |
CCTGTCCCAA |
CCAGAGCCGG |
GGAGGAAAGG |
GTGGCCCGGA |
GGGTGGCCTC |
TTGCTGGGGT |
CTGGGTTGGG |
GGCGGGGGAG |
|
12801 |
ACGTTTGCTT |
TGAACAGATT |
CTTGGGGCCA |
GCTTAGGGAC |
TGTGCTCTGT |
GACTTTTGGA |
GCGCGTGGAC |
CATGGAGGGG |
|
12881 |
TGGGGGTGGG |
TTTCTTGGGG |
TGTAAAGTGG |
GAGAGTTCCC |
AGAGAAGGAA |
GCTAAGAAAT |
AAGGCCAGAT |
GGGAGCCTAG |
|
12961 |
GGAGGGCTGC |
GTTGTTCTGC |
TGCCTTTTCC |
TTGGTGCTGT |
GCGTGGGGAA |
GGGTGAGTGG |
GGGCAGTGTG |
TATCCTGACC |
|
13041 |
CATCTGTCCA |
CCTGTGTGCA |
TTAATCATAA |
AAGCTAACAT |
ATAGCCTGGG |
CCAGGTATAC |
TCTGCCAGGA |
ACTGTTTGTG |
|
13121 |
GTGTTTTGCA |
TGCATTCTCC |
TTTAATCCTA |
GAACACCCCT |
ATAGTGGAAG |
TTCTGCCAGC |
ATTCTGGACT |
GAGTAGCAGT |
|
13201 |
CCAGAGGTTG |
AGTAGCAGCT |
AGTAAGTGGT |
GGGGTCAAGA |
TGGGACCCCA |
GGCAGTGCGA |
CCCCCAACCA |
TGCATTCGAA |
|
13281 |
ATCGCTATAT |
GGATGAGTGC |
ACCTGGAGCA |
ATGAGGGACA |
CTGCTCCCTG |
AGTCACTGGG |
CTGCAGGGGA |
GACAAAATGA |
|
13361 |
AAGTGTTCTG |
GGAGTCGTGG |
GTGGTCTCCA |
TAGGTCAGAG |
GGTCTGGGGA |
GGGAGTGGGT |
GTCATCGTGG |
CTGTGTGTTG |
|
13441 |
CCCGAGGGGC |
CCTCTGTGAG |
TGAGTGCATG |
GCCGTGTTAT |
CTCTGCAGGT |
CTACGCCAGG |
GTGTTCCTCA |
GTTGTGTGGT |
|
13521 |
CTTTGTATTT |
GTGTGTCTGG |
GCTTTGTGTT |
GCCAAACAGC |
AGTCTCTCTG |
CTGACTTGGG |
GACACAGGCT |
GAACTCTGTC |
|
13601 |
CTCTGCAGGA |
ACTCCCTTAA |
GGTGCTGGGC |
CAGATCTGCC |
ATAAACAGAG |
GGAGGTAGCC |
TTCTATGGCC |
ACGCCTTCTT |
|
13681 |
GCTGAGGAAG |
AAGGTTCCTC |
TCTTCCAGGG |
AGTACATCCT |
TGCCCTCCCT |
GTTTCCCAGA |
CAAGCATCTT |
CACCTCTCAT |
|
13761 |
CTTCTGATGA |
GAAGGGTGAG |
GCCATACTGA |
GCTGTCAGGC |
TGAGCTGCTG |
CCCTTCCTCA |
CCTTGGGCTG |
GGAGTTGATC |
|
13841 |
AGGGAATGGC |
AGTTGCTGCA |
GAGCTGGATT |
TGAGGGCTGG |
GTTCTCTGGA |
TGGGGCCTCC |
TCATGTCCTC |
ACCCCTCAAC |
|
13921 |
CTGCACTATT |
GATTGTGTTG |
TGCAGGAGTT |
AGTTAAAAAG |
TCATTGCACA |
GCCTGGGCAA |
CAAGGCAAAA |
CTCTGTACAA |
|
14001 |
AAAATACAAA |
AATTAGTTGG |
ATGTGATTAC |
ACGTGCCTGT |
AGTCCCAGCT |
ACTCCGGAGG |
CTGAGGCAGG |
AGGATCACCT |
|
14081 |
GAGCCCAGGA |
AGTTGAGGCT |
TGCAGTGAGC |
TGTGATTGCA |
AATGCTCTCC |
AGCCTGGGTG |
ACAGTGTGAG |
ACTCCGTTTC |
|
14161 |
AGAAAAAAAG |
TATACCACCC |
AGCTGCCTCC |
AGCACCCAGA |
TTTTACCCAA |
GGGGTGAGGT |
CTGGGGCAGG |
AATGTGGGGG |
|
14241 |
AAGGGGAGGC |
CTAGGGGGAG |
CCCCAGAGGG |
GTCAGGATTT |
TTCTGAAATC |
CTTTCTTAGA |
GGTATGGGTT |
TTACAAATTG |
|
14321 |
CAGCAAATAC |
ATCCTTTTAA |
TCTTGCAGAA |
CTCCTTCATA |
TTTTAATTCC |
AGTATGATTC |
TTCCAACAGC |
CTCCTCTCTT |
|
14401 |
TACTATACTT |
GGGGAAAGTA |
CTCATTTTAT |
TTGTCAAGAA |
AAAAACAATT |
GAAAAGATAG |
GGATCAAATG |
TAAAAAGAAA |
|
14481 |
AAATACGTGG |
CATTCCAAAG |
TCAAACACAA |
AGCATGTTTA |
ATTTTCTCGT |
GGTTTGGGAT |
TACCCATATT |
CCTGCTGTAT |
|
14561 |
GAACCTGTCT |
TGTCTTAACT |
TTTAAGAAAT |
GTACGGTGTA |
CTTCCTATAT |
GCTAGGTTTT |
TATCCATGCT |
TTCATTTAAT |
|
14641 |
CTCTGTGACA |
GTCCTGTGAA |
GTAGGTGCAC |
AGATGAGAAA |
ATGGAAGTTC |
AGAGAAATGA |
AGCAACTTAT |
CCAAGGCTCC |
|
14721 |
CAGCTACCCA |
GTAATGTCCA |
GGGAATTTTT |
GGACTCTGAA |
GAGGAGGCAT |
TAAGAGGTGG |
TTAGAGTCTT |
ATTCCAGCCA |
|
14801 |
ACAATAATGG |
GTTGAACAAA |
GCCTTAGGGG |
CAGGCAGGTG |
GCCAGATGGG |
AGGAGAAGCG |
CTCCTCTTGT |
TCAGGCGAAT |
|
14881 |
GACCTTTCCA |
TCCACTTCTC |
TAGGCTGTAG |
AAAGTGGAGC |
TGAGCTGGGG |
GCCCTGAGGT |
TCCCTCTTGA |
CTTCAGAGTC |
|
14961 |
CTCTCCCTTC |
CTGTCCAGCC |
AATGCCTGTC |
TTCCTTTTGG |
GCCCTACCAG |
CATGACAGGG |
GGCTGCGGGC |
AGGAGGGGAC |
|
15041 |
AGAGGCCACG |
TTGACACACA |
GGGCTGTGGG |
TGAGAGAGAC |
AGCTGAAGTG |
TCAGCGTGAG |
GGGCCAGTGT |
GGGGCTGCGG |
|
15121 |
CTGGGAGGGC |
TGGGGTGGGG |
CCCAGGGTAG |
TTGTGCCTGT |
CCTTGGGTGA |
TGGAATGATC |
TGGAAAGAGA |
TTCCTTCCCT |
|
15201 |
GCCCTCCACC |
TGTGAGAAGC |
CCCTCTAGAG |
TGACATCTCC |
ATCTTATGTT |
TGGCCACCCA |
TCCTCCCCCT |
GGGAAGAGAG |
|
15281 |
CCGAGGTGGG |
GTAAGGGATG |
TGTACTCTTT |
CAAGGAGTGG |
GAGAATTATT |
CTAGCGAATG |
TTTGTGTTGT |
CCCAGTTCTG |
|
15361 |
TTTACAAAGC |
CTCGTCATGT |
TTACAGATGG |
CTGCGCAATT |
CATTACCTCA |
TTTAACTCTC |
ATGTACCTCC |
TCTGAGGGAG |
|
15441 |
TAAGAGCTGT |
TACAGCCAAG |
TTTAGGTCAG |
TAAATATTCA |
CCAAGTTGCA |
GGTACTGCAG |
GGCATAGAGA |
TGAATCCGAT |
|
15521 |
TTAGCTTCTG |
CCCTGGAGGT |
CTGGGAACTT |
GCTCAAGATC |
ACTCAGTGAG |
CAGCTGAGCT |
AGGGTTCTCA |
ACTAAAGACC |
|
15601 |
CTGGGCCCAG |
GCCCTGGTCT |
GATGTCAGGC |
CTGATACACC |
AGGTGTTTGT |
GGTCGGGGAA |
TCCCAGTGTC |
ACTTGAATGG |
|
15681 |
GCTGTGACAT |
TATGGGTCTG |
GGAGAGCTGA |
GCTTTGGGGA |
CACAGGTCAT |
TTTACTGTAG |
TATTCATGGA |
AACCAAGGGA |
|
15761 |
AGTATTGGCT |
TTTCTGCTGT |
GAGCAAGAGG |
AGCAGCTGGG |
GCTGCAAGCT |
GGTGGGGAGG |
AGAGAACCCA |
CCTGAGAGAA |
|
15841 |
ACCTCAGGAC |
TGGGGTCAAG |
TCCTGACCAC |
CAGAGTCCAG |
AGAGACATGA |
AGGACTGTGA |
CCAGCTCTGA |
GCAGAGAGAT |
|
15921 |
GGATTCCATG |
ACCTCAACTG |
GTCCCTTTTG |
TTCGGAGACT |
CGTGACTGGA |
CTTCATTCAT |
CCACTCATTC |
ATTCATTCAC |
|
16001 |
TCAGCAGACA |
CTTATCTAGC |
GCTCCCTGTG |
GCTGGTCCTG |
CCTCATACTG |
TCTTTGCTCT |
GGAGAATTGG |
AGGTTGGGGT |
|
16081 |
TCCTGAGGGG |
CAGGGTCCTG |
GAGACAAGGA |
CACTCCTGGG |
TAGAATTAGG |
ACCTACCCCC |
CAGGAAATCA |
ACGGGGACCA |
|
16161 |
GGTGCCGTGG |
CTCACACCTG |
TAATCCCAGC |
ACTTTGGGAG |
GCCGAGACGG |
GCGGATCACA |
AGGTCAGCAG |
TTCAGGACCA |
|
16241 |
GCCTGGCCAA |
CATGGTGAAA |
CCCGCCTCAA |
CTAAAAATAC |
AAAAATTAGC |
CAGGTGTGGT |
GTCAGGCACC |
CGTAATCCCA |
|
16321 |
GCTACTGAGG |
AGGCTGAGGC |
AGGAGAATTG |
CTTGAACCCG |
GGAGGCAGAG |
GTTGCAGTGA |
GCCGAGATTG |
CGCCACTGCA |
|
16401 |
CTCCAGCCTG |
GCGACAGGGC |
GAGACTCCAT |
CTCAAAAAAA |
GAAAACCAAT |
GGGACAGGGC |
AGATATGGGG |
ACAATGGTAA |
|
16481 |
GGAGATGGGA |
GAGTGGGAGG |
GAGGTGTCAG |
GAAGACCTTC |
TTGACTTCAT |
GTAGGCTGGT |
GGGGGTGTTA |
GCCAGCAAGC |
|
16561 |
CTCCAGTTCC |
CTGGGAACCG |
TTCTCAGGGT |
ACCAATTTTA |
CCACCTGTCT |
GCAAACACTT |
TAAGATTCTT |
AATCAGACTC |
|
16641 |
AAATTGGCCA |
CAAATCAGGT |
AAACAAACTC |
ACTAGTGGGG |
TGGGGCTACC |
ACCCGTTCTG |
ACCCTCCAGC |
CCAACCCAGC |
|
16721 |
CCAGCCACCC |
TGCCCTCCGT |
AGAGCCTGTG |
GTGTTTATCG |
GTGGCATTGG |
GAGAATTAGT |
GTGTATTTAT |
GTTGGCGTGG |
|
16801 |
GGTGTGGGGT |
GGATTTGTGT |
GTGTGCAGTT |
AGGCCTAGTG |
GAAGGAATGT |
GGGATCTGAA |
GGCAGGCCAG |
CCTGAGTTCC |
|
16881 |
AGTCCTGCCT |
GTTGCTCACA |
AGCTTTATGA |
GGCGAGAGCT |
AACCCCTGCC |
AGCCTCAGTT |
GTCTTCTTTG |
CAAGATGGAG |
|
16961 |
GTTGCAGCCC |
CAGTCTCTGG |
AGCATGTTAT |
GCAGATCCAC |
CGAGAGTGCC |
TGCCAGGCAC |
ACAGTAGGTG |
CTCAGCTCAG |
|
17041 |
TTACTGTGGC |
GGCCCCCACT |
CCCCATTGTT |
GTTGTTTTCC |
TATTGCCTGG |
CGGCCACAGC |
TGGTATCCCT |
TGAAAAGGGC |
|
17121 |
TACAGGGGGT |
GGAGTCGGAC |
CCTGCCCCAG |
CCCTGTGGAG |
ACCCTGGGCT |
TGGGCCAGGG |
CCTGGGGTCT |
GGGCCTGCAG |
|
17201 |
ACAGCTGTGT |
CTATAAAGCA |
GCTGAAGGGC |
TGAGGCCGGG |
GGAGGTCCTG |
GCAGCAGGGC |
GTTATTTTGG |
GCCTGGCCTG |
|
17281 |
CCACCCCCAG |
CTCCTGTTTC |
TCTTGGGAGT |
CTGTTGGGGG |
AGGAAGTGTG |
GGGAAGAGGA |
GGGGGTGCAA |
GTGGGTGAGG |
|
17361 |
CATGGAGTGG |
GGAGGCCTCC |
CTCAGGGACA |
TGGACCCTTG |
AGTTCTATTT |
CTGTTCCTCC |
CTCCTGTTCC |
TCCCTCTTTG |
|
17441 |
TCCTTATCTG |
CCTAGAGAGG |
TGGGAATAGA |
GGCCATTCTG |
AGTATCACTA |
GGAGACCACC |
AGTTTGTGGC |
CACTGGCCAC |
|
17521 |
TGGCCCAGGC |
AGGGAACCTG |
GGGGCTTGCC |
CTACCAGCCT |
CTCCCAGCAA |
TCTGAAGGCA |
GGGGGTACCT |
CGTATTACCC |
|
17601 |
CCTAGGATTT |
GACCTTAGGC |
TCCAACTTGC |
TGGGAGAGCA |
GTGCCTCTGG |
TGTCAGACCC |
CAAGCCAGCC |
CTTGTGCTGT |
|
17681 |
CCCTGAATCT |
GCATGTAGCC |
TGTGGGAGGC |
GGAGCAGTGA |
CCGGCAGGAA |
TTCTGGGCAG |
CTCAGGCACC |
TGTGGGCCTG |
|
17761 |
AGGGTGCCCT |
CTGCCCCCAC |
CCTTCCGATC |
TCCTGGGCAA |
GACACGCCAG |
GTGATTCATC |
TCACCAGAGC |
AGAAAAACAA |
|
17841 |
GTTCAACTGG |
GCACTTTAAT |
CTCCCCTCAC |
TGGCAGGCCT |
GGTGTGAGCT |
GCTACCCCGG |
CGCCCCTCAC |
CAGGGGTGCT |
|
17921 |
TTACCTCCTC |
TAGTATTCCT |
GACCTTAGTG |
GGCATTTCTG |
GTCTCAGGGA |
TACCAGGCTG |
GGGTCCAAGT |
GGGCCAGGTG |
|
18001 |
TGGCAGTTCA |
GCCCTATGCC |
CCATGGCTGA |
TGGCTCGCGC |
TGGGCAGGTA |
TGCAGGGCTG |
ACGTAGTGCC |
TTTGTGGCAG |
|
18081 |
CAGTTTCGTG |
GCACACATTC |
TGCCAGCTGG |
TTCTGGAGTC |
TTGCCCTGAG |
GAGGTGGCCA |
GGGTGAGGGT |
GCCAGCGCAG |
|
18161 |
GAACCTTTGG |
CGCATGCTTC |
ACCCTGGCCT |
GGGATCTGCA |
GCCTGGGTCC |
AGATGCCCAC |
AACTGGAATC |
TGACGCTCCT |
|
18241 |
TTTCTCTTCA |
TGGGGGACTC |
CCAGAGGTCT |
CTGCAATGAC |
CAGAGCCCCG |
GTTGTCCCAT |
GCCTCAGCTG |
CAACTCCAGC |
|
18321 |
TGACCCTCCT |
TCCCCACTCT |
CTGGGTGGCA |
TTACGGGGGT |
GTGGATCCCT |
TGCCAAGAGG |
TTGGCATGTG |
GGTGTGCTGG |
|
18401 |
AATGGCATAG |
GGAGAATGCA |
CCGAGTTTGT |
TTGCTTGGGA |
GAGGGGCAGG |
GGGTATCCAG |
AAGATTCATG |
ATTCGTCATC |
|
18481 |
GCCTCTCTTG |
GGGGATTTTT |
ACCCCTTTGC |
CCTGAGTTGT |
GCCTTTGGGA |
CAAAGGAAGC |
CTTTCTTTGC |
CAGCCAACAC |
|
18561 |
CCTGTACTGG |
CGGGCGAGCT |
CCCCAGGGCT |
GGCACGCTGG |
GGCAGCCTCT |
GAATGCACAG |
GGTGGGCCTA |
GTCAGAAGAA |
|
18641 |
GCCTTTCCCC |
TGAAATCCCT |
CTACTTCCCA |
AGCACGCAAG |
CTTTCTCCTG |
CTGTTAAACC |
TGCAGTGTGC |
AAGGGACATG |
|
18721 |
GGCGGAGGGG |
TCCTTCAGTC |
AGGCTTCTCC |
CTGTCTGAGG |
TGGCATGACT |
TGGAGTGAGT |
TTGGATGGGG |
TGGCCAGGTC |
|
18801 |
TGAGAAGGTC |
CCCCGCCAGT |
GTCCTCTGAC |
CCATCTGCTC |
TCTCCTGCCA |
GTGTGCACCG |
GCACAGACAT |
GAAGCTGCGG |
|
18881 |
CTCCCTGCCA |
GTCCCGAGAC |
CCACCTGGAC |
ATGCTCCGCC |
ACCTCTACCA |
GGGCTGCCAG |
GTGGTGCAGG |
GAAACCTGGA |
|
18961 |
ACTCACCTAC |
CTGCCCACCA |
ATGCCAGCCT |
GTCCTTCCTG |
CAGGTGAGGC |
CCGTGGGCAA |
CCCAGCCAGG |
CCCTGCCTCC |
|
19041 |
AGCTGGGCTG |
AGCCCTCTGT |
TTACAGGTGG |
GTGGCAGAAG |
AAGGTGCCCT |
GCCCTTCTGT |
TTCCTCTCTT |
GTTGTGGTTT |
|
19121 |
CTCAACCAGG |
AAGTCCTTTC |
TAACATCTAA |
CCCCCATTCA |
TTTTACTGCA |
GAATCAGTTG |
ACTCTCTCTA |
TAACGTGGCT |
|
19201 |
GGCCGAGGTC |
ATGTCTGGAT |
GGGATGCGTC |
TGTGTTTCCG |
CTAAATCTTG |
TGCTCTCTTG |
CCAGCATGAT |
CATGTCCCCT |
|
19281 |
GTCCACCTGC |
TCCAGCCACT |
ATCCCTCTCC |
CACTTACAGC |
AGAAGAAAGG |
GCTGGTGAGA |
AAGGTGGATT |
ACAGGCCCAC |
|
19361 |
TTCTGCCACT |
GACGAGCCCT |
ATGAATGTGG |
CCTACACCCC |
CTTAGCTTCA |
CTGGGTCTCA |
GTTTCCCTAT |
CTGTATATTG |
|
19441 |
GGAGCAGTTG |
TGAAGCTCAG |
AAGAGAAATG |
TCTGTGAAAA |
GGTTATGAAC |
AGGAGGGAGA |
GTGGAAACCA |
ACCTGCTGGA |
|
19521 |
TCGTGTCCAC |
AGACCCTGGA |
ATGGGGCCAC |
ATGCTTGGTT |
TGTCAAATTG |
CAGACGCCGG |
CCGGGTGCGA |
TGGCTCATGC |
|
19601 |
CTGTAATCCC |
AGCACTTTGG |
GAGGCCGAGG |
CGGACAGATC |
ACTTGAGGTC |
GGGAGTTCGA |
GACCAGCCTG |
ACCAACATGG |
|
19681 |
AGAAACCCCG |
TCTCTACTGA |
AAATACAAAA |
TTAGCCAGGC |
ATGGTGGCAC |
ATGCCTATAA |
TCCCAGCTAC |
TTGGGAAGGC |
|
19761 |
TGAGGCAGGA |
GAATCACTTG |
AACCTGGGAG |
ACGGAGGTTG |
TGGTGAGCCT |
AGATCGTGCC |
ATTGTACTCC |
AGCCTGGGCA |
|
19841 |
ACAAGAGTGA |
AACTCCGTCT |
CAAAAAAAAA |
AAATTTGCAG |
ACGCCATCCC |
ATCCAGGCCT |
TTGCTTTCAC |
TGATGAAGAA |
|
19921 |
ACTGAGATAC |
AGAGAGGGCA |
GGGCACCTGT |
TCGGAGTTTA |
TGAAATGCCC |
CCCCACCATT |
ATCTTTCTTG |
ATCATATAAG |
|
20001 |
AATCTGGTGA |
GGCAAGGTAG |
GGCGTGATCT |
TTATCTCTAT |
TTTATCGTTT |
TATTTAAGCG |
GGAACAGGAC |
TGCTCAGTGG |
|
20081 |
CTGGGGGCCT |
TGCCCAAGAT |
CTCCAAGTAC |
TGGGGAACCC |
CAGGGAGGCC |
CTGGGGGGTG |
GCAGTGTTCC |
TATTTCAGCC |
|
20161 |
CCACTCTGCT |
TCCCCCTCCC |
AGGATATCCA |
GGAGGTGCAG |
GGCTACGTGC |
TCATCGCTCA |
CAACCAAGTG |
AGGCAGGTCC |
|
20241 |
CACTGCAGAG |
GCTGCGGATT |
GTGCGAGGCA |
CCCAGCTCTT |
TGAGGACAAC |
TATGCCCTGG |
CCGTGCTAGA |
CAATGGAGAC |
|
20321 |
CCGCTGAACA |
ATACCACCCC |
TGTCACAGGG |
GCCTCCCCAG |
GAGGCCTGCG |
GGAGCTGCAG |
CTTCGAAGCC |
TCACAGGTGG |
|
20401 |
CCTTCACCGT |
CATTGAAACC |
TTCTCTTGGT |
TATTCAGAGC |
TGACCAGGGC |
CACTGCTAAC |
CAGGGGGAGG |
CTTTGTGTGC |
|
20481 |
ATTAGAAATG |
GTGTCCCTTC |
TGGGCAGACG |
CAGGCAGAGC |
CCGGGAAGAC |
GCCCTCAGAA |
GATTGGAAAA |
AGATTCCCCT |
|
20561 |
TCTTCCTGGG |
AAGTTGTAGC |
TTGCGTCAGC |
ACATATAATT |
CAATCGTGAG |
AATGCAGGCT |
GGGTTTTTGC |
CCCCACTTGG |
|
20641 |
CTGAGTGAAG |
TGTACAGTGA |
ACAACCTATG |
TAACTATTTG |
CTGGCCCTGG |
AGCCGACTCT |
GCCCCAGAGT |
CTGGGTGCCA |
|
20721 |
GGTGCTTTGC |
CCGCATGGCC |
CATTTCAGTC |
ACGCTGCAGT |
CCTGTCAGGA |
AAAAATCAGT |
GTTATTCTCA |
TTCTACATAT |
|
20801 |
GAGAAAACTG |
AGGCTTGCAG |
ATATAAGGGC |
CAAAAGTTAC |
ACAGCTAGTG |
AGTGATGGGG |
CTGAGTTTCA |
GACTCCACAG |
|
20881 |
TCTCTTAACC |
ACCAAGCAGC |
ATGCCCAGAG |
TAGAGGTGAG |
AAGGAAGGAG |
AGAGCTGCGG |
TCCACATGAG |
CATCTGGACC |
|
20961 |
TAGCATGGAC |
AACTCACTCC |
TCCCTGGCTC |
TCGCTTTGTT |
CTTGTTGCGG |
GTGTGGTGGT |
GGTGGGACTC |
AAAGACGGTA |
|
21041 |
AAGATAGCTT |
TCTCTCCTCC |
CTGGGGAATC |
TGGGGGTTGT |
TTAAAAGGCC |
TGCTCCTCTT |
TTAGAAGGCA |
GGAGGGCCCC |
|
21121 |
AAGGGAAGCA |
GAAGGTGACA |
GAAGGGGAAA |
GGGTCCTCTG |
ATCATTGCTC |
ACCCCACAGA |
GATCTTGAAA |
GGAGGGGTCT |
|
21201 |
TGATCCAGCG |
GAACCCCCAG |
CTCTGCTACC |
AGGACACGAT |
TTTGTGGAAG |
GACATCTTCC |
ACAAGAACAA |
CCAGCTGGCT |
|
21281 |
CTCACACTGA |
TAGACACCAA |
CCGCTCTCGG |
GCCTGTAAGC |
CATGCCCCTC |
CCTGCTGCCT |
CTTCTCTCAG |
ACAGCCTGAC |
|
21361 |
CCCAGCCGCA |
AACTCCCAAC |
TTACAACCCA |
GTGCCTGCCC |
GCCACTGCCC |
CAGCCGCCTA |
CACCACCCAT |
TTCCTCCCTC |
|
21441 |
TCTGTCCCTC |
CTGCCATCTC |
CCTGTGCCTC |
TTCATCTCTG |
GGGTTCTCTG |
TCTTGTCTCC |
CTCTGCTTAT |
AGGTTGTGCC |
|
21521 |
TCTGGTTTGG |
GGGCCTCTCA |
GCCTGTCTGG |
GTCCCTCCCT |
TGCTGTGCAG |
TTGGCCTCGT |
GGCCTCTGCT |
GCTGTTTGTG |
|
21601 |
CCTCTCTCTG |
TTACTAACCC |
GTCCTCTCGC |
TGTTAGACAT |
CTCTCTCACT |
GCCTGTCTCT |
GGTTCTGTCC |
TCAGGCCACC |
|
21681 |
CCTGTTCTCC |
GATGTGTAAG |
GGCTCCCGCT |
GCTGGGGAGA |
GAGTTCTGAG |
GATTGTCAGA |
GCCGTGAGTC |
TCAGGGAGGC |
|
21761 |
CTGGAGTCAG |
GGAAGGGGAG |
GGCTGGGGCC |
GGGTGGAATG |
CAGGTGTCAT |
ACAGGTGACA |
TGGGAGGGGT |
GGGATAACAG |
|
21841 |
GCTTGGGATG |
TCTCCCCTGG |
GCCAGGTAGT |
CTCCCTAGAA |
GGTGATGCTG |
ATGAGGGTCT |
GGTGCCCAGG |
GCGCCACTCA |
|
21921 |
GCCCTCATCC |
TGCCCTTTGC |
CCAACAGTGA |
CGCGCACTGT |
CTGTGCCGGT |
GGCTGTGCCC |
GCTGCAAGGG |
GCCACTGCCC |
|
22001 |
ACTGACTGCT |
GCCATGAGCA |
GTGTGCTGCC |
GGCTGCACGG |
GCCCCAAGCA |
CTCTGACTGC |
CTGGTATGTG |
CCTCTGCTTT |
|
22081 |
GTGCCCAATG |
TGCTCTACCC |
CCCAGGATGC |
AAGGGGTGGG |
CACCCTGCCT |
GGTACTGCCC |
TATTGCCCCT |
GGCACACCAG |
|
22161 |
GGCAAAACAG |
CACAGTGAAA |
GCCAGCCACC |
TGTCCCCCCA |
GGCCTGCCTC |
CACTTCAACC |
ACAGTGGCAT |
CTGTGAGCTG |
|
22241 |
CACTGCCCAG |
CCCTGGTCAC |
CTACAACACA |
GACACGTTTG |
AGTCCATGCC |
CAATCCCGAG |
GGCCGGTATA |
CATTCGGCGC |
|
22321 |
CAGCTGTGTG |
ACTGCCTGTC |
CCTGTGAGTG |
CCAGGGAGAA |
ACACAGTTTT |
CTCATTTTGG |
TGGGGAGGTT |
TGTTTCTGTA |
|
22401 |
AATGGGAGCA |
TATGGGGAGC |
ACTGTCTGCA |
TCTTGCTTTG |
AGAGCTGGTC |
ATGACAGTTC |
CTGCCGAGCT |
GCCTTGTTCT |
|
22481 |
TTCAACAGCT |
GTGGAGCAGG |
TGGCAGTAAG |
GAGAGGCAGC |
TAAGAGCCCA |
GACTTGGGAG |
CCAGACTGCC |
TGGGTTTGAA |
|
22561 |
ACCCAGCTCT |
ATCAATTAGT |
AGGCACGTGA |
CCCTCTTGCT |
GTGCCTCAGT |
TTCCTCATCA |
GTAAAATGGG |
GGCAAGAATA |
|
22641 |
GTCCCAACTG |
CATAAGATGG |
TTATAACATT |
TGAAAGAGTT |
AATATTTGTA |
AAGCTCTTAG |
AACGGTGCCT |
GGTATGTACT |
|
22721 |
AAGTGCTCCT |
AAATGTTAGC |
TTTTATTCTA |
TAGCCTGGTG |
AGGTCAGTTT |
TACCTTTCGT |
TTTGTTTTTG |
AGACCGAATT |
|
22801 |
TAGTTAGCTC |
TATCGCAGTG |
GCGCGATCTC |
GGCTCACTGC |
AACCTCCGCC |
TCCCAGGTTC |
GTGCTATTCT |
CGTGTCTCAG |
|
22881 |
CCTCCTGAGT |
AGCTGGGATT |
ACAGGCGCCC |
ACCACCATGC |
CTCGCTAAAT |
TTTGTATTTT |
TAGTAGAGAC |
AGGGTTTCAC |
|
22961 |
CACGTTGGCC |
AGACTGGTCT |
CGAACTCCTG |
ACTTCAGGCG |
ATCCACCTGC |
CTCGGCCTCT |
GAAAGTGCTG |
GGATTACAGG |
|
23041 |
CGTGAGCCAC |
TGCACCCGGA |
CTTTTTTTTT |
TTTGGCAGAG |
TCTCGCTCCA |
TTGCCCAGGC |
TGGAGTGCAG |
TGGTGCAATT |
|
23121 |
TTGGCTCACT |
GCAACCTCTG |
CCTTCCGCAT |
TCAAGCAATT |
CTTGTGCCTC |
AGACTCTTGA |
GTAGGTGGAA |
CTACAGGCAT |
|
23201 |
GCACCACCAT |
GGCTGGGTAA |
TTTTTGTATT |
TTTAGTAGAG |
ACGGAGTTTC |
ACTATGTTGG |
CCAAGCTGGT |
CTCGAACTCC |
|
23281 |
TGACCTCAAG |
TGATCCACCC |
GCCTTGGTCT |
CCCAAAGTGC |
TGGGATTACA |
GGCATGAGCC |
ATCGTGCCTG |
GCCTAGCTCA |
|
23361 |
GTTTTATTTA |
ACAGATCACC |
TATTTACTGA |
TGGGCGTTTA |
TGGACTGGGC |
TCAGACCTGG |
GGAACCTCTT |
TCCTCCTCTC |
|
23441 |
ACAGGAACAG |
GAGTGGGCCT |
TCAGATCCTG |
GCTGACTGTG |
TTAGGGAGAG |
GACAAAATGT |
AGAGCCAGAC |
CATTTGGGTT |
|
23521 |
CAAATCCTCG |
CTCCTCCACT |
CACTAGCACA |
ATGACCTTGA |
ATAATTTACA |
GAACTCTCTG |
CTTTGGTCTC |
CCTTTTTGCA |
|
23601 |
AAATGGGAAT |
CTCACAGTGC |
TGATCCCGTC |
TGGTTGTTGT |
GAGGGGTAAA |
TGGATGTCAG |
GTGCTGATGC |
GTGGTAGGGC |
|
23681 |
ATTTAAGTAT |
TGGTTGATAT |
TATTCTTCTT |
GTGCCTGGGC |
ACGGTAATGC |
TGCTCATGGT |
GGTGCACGAA |
GGGCCAGGGT |
|
23761 |
ATGTGGCTAC |
ATGTTCCTGA |
TCTCCTTAGA |
CAACTACCTT |
TCTACGGACG |
TGGGATCCTG |
CACCCTCGTC |
TGCCCCCTGC |
|
23841 |
ACAACCAAGA |
GGTGACAGCA |
GAGGATGGAA |
CACAGCGGTG |
TGAGAAGTGC |
AGCAAGCCCT |
GTGCCCGAGG |
TACCCACTCA |
|
23921 |
CTGCCCCCGA |
GGCCAGCTGC |
AGTTCCTGTC |
CCTCTGCGCA |
TGCAGCCTGG |
CCCAGCCCAC |
CCTGTCCTAT |
CCTTCCTCAG |
|
24001 |
ACCCTCTTGG |
GACCTAGTCT |
CTGCCTTCTA |
CTCTCTACCC |
CTGGCCCCCC |
TCAGCCCTAC |
AAGTGTCCCT |
ATATCCCCTG |
|
24081 |
TCAGTGTGGG |
GAGGGGCCCG |
GACCCTGATG |
CTCATGTGGC |
TGTTGACCTG |
TCCCGGTATG |
AAGGCTGAGA |
CGGCCCCTTC |
|
24161 |
CCCACCCACC |
CCCACCTCCT |
CAGTGTGCTA |
TGGTCTGGGC |
ATGGAGCACT |
TGCGAGAGGT |
GAGGGCAGTT |
ACCAGTGCCA |
|
24241 |
ATATCCAGGA |
GTTTGCTGGC |
TGCAAGAAGA |
TCTTTGGGAG |
CCTGGCATTT |
CTGCCGGAGA |
GCTTTGATGG |
GTAAGAGTGG |
|
24321 |
GCACGATGAC |
CTGAGACAGT |
GTCAGGGCAG |
ACAGAGTCCT |
GAGGATCCAG |
ATGTGGCAGC |
ATCTCTTGGG |
GATGGCAGGA |
|
24401 |
GACAGAAGTG |
GGGGGATCAA |
GAATGCAAAG |
AAAGCAGATG |
GGAGACCAGA |
GGAGCAGGGC |
CTTTGGTGGG |
TGGGGGTGAT |
|
24481 |
TATTTTTGTA |
AATGACATGC |
TATCCGTGAA |
CAAGGACTTG |
TATGGAGGTC |
AGACCATCTA |
GATAAAGTAA |
AATTCCCTTT |
|
24561 |
GAGTTCATAG |
CAGCTTTATT |
CAAAATATCC |
CCAAATTGGA |
AATAACTCAA |
ATGTGCATCA |
CTAGGTGAAG |
GAATAAACAA |
|
24641 |
GTGGCAGTGT |
ATCCATTTGG |
TGAAGTTCTA |
CTTAGCAACC |
AAAGGAAATG |
AACTACCGAT |
ACAACATAAA |
TGAATCTCAG |
|
24721 |
AAACATTACA |
TTGAGCAAAA |
GAAGCCAGAG |
ACAAGATTCC |
ATACTGTCTG |
ATCCCCTTTA |
TGTGAGGCTC |
TGAACCGAAA |
|
24801 |
AAACCACTCT |
GTGGTGGGAG |
AGATCAGAAC |
GGTGGTTGCC |
CCAGGGTGGG |
GGGCTTCAAA |
AGGGAGGCAC |
ACAAGGACAT |
|
24881 |
TTCTGGGGTA |
ATAGAAATGC |
TCTGTATAGT |
GATTGGGGTA |
GTGGATACAT |
GAGCGAATCC |
ATTTGTCAAA |
ACTCATCAAA |
|
24961 |
CTGTGTGATA |
AGAGTCTGTG |
CATTTTATTT |
ATTTCATTTT |
ATTTTTTGAG |
ATAGAGTCTC |
ACTCTGTCAG |
CAGGCTGGAG |
|
25041 |
TGCAGTGGTA |
CGATCTTGGC |
TCACTGCAAC |
CTCTGCCTCC |
TGGATTCAAG |
CAATTCTCCT |
GCCTCAGTCT |
CCTGAGTAGC |
|
25121 |
TGGGACTACA |
GGTGTGTGCC |
ACCATGCCCA |
GCTAATTTTT |
GTATTTTTAA |
TAGAGATGGG |
GTTTCACCAT |
GTTGGCAAGG |
|
25201 |
ATGGTCTCGA |
TCTCTTGACG |
TCGTGATCCG |
CCCACCTCAG |
CCTCCCAAAG |
TGCTGGGATT |
ACAGGCATGA |
GCCACCACAC |
|
25281 |
CCGGTGCATT |
TTATTGTATA |
TAAGTTATAC |
TTCAATAAGA |
AATGAATTGG |
GGCCAGGCAC |
GGTGGCTCAC |
GCCTGTAATC |
|
25361 |
CCAGCACTTT |
GGGAGGCCGA |
GGCAGGCAGA |
TCACTTGAGG |
TCAGGAGTTC |
AAGACCAGCC |
TGGCCAACAT |
GGTGAAACCC |
|
25441 |
CATCTCTACT |
AAAAAATATA |
AAAAATTAGC |
CAGGCTTCCT |
GGCATGCGCC |
TATCATCCCA |
GCTACTTGGG |
AGGCTGAGGC |
|
25521 |
AGGAGAATTG |
CATGAACTCG |
GGAGGTGGAG |
GTTGTAGTGA |
GCTGAGATTT |
CGCTATTGCA |
CTCCAGCCTG |
GGCGACAGAG |
|
25601 |
TGAGACCCTG |
TCTCAAAAAG |
AAAAAAAAAA |
AAAAGGGTCA |
GGCGCCGTGG |
TGCACACCTG |
TAATCCCAGC |
ACTTTGGGAG |
|
25681 |
GCTGAAGCAG |
GAAGATTGCT |
TGAGCCCAGG |
AATTCAAGAA |
CAGCGTGGGC |
AACATAGTGA |
GATCCCATCT |
CTACAAAAAA |
|
25761 |
ACACAAAAAA |
TTAGCCGGGC |
ATGGTGGTAC |
GCACCTGTAG |
TCTCAGCTAC |
TAGGGAGACT |
GAGGTGGGAG |
AATCACCTGA |
|
25841 |
GCCTGGGAGG |
TGGAGGTTGC |
AGTGGGTTGA |
AATCATGTCA |
CTGTACTCCA |
GCCTGGGTGA |
CAGAATGAGA |
CCCTGTCTCA |
|
25921 |
AAAAAAAAAA |
AAAAAAAAAA |
ATTCCCTTTC |
ACACTTCCTT |
TACCTCCACT |
CCCCTTTCCA |
GAGGGGGCCA |
TGGTTAACAG |
|
26001 |
TGTGTGTGTT |
CACCTAGACC |
GTTTATGCAT |
CTGTAGACAC |
ACACACAGTG |
AAGTGTGGTT |
TTCGTCGTTT |
TGGTGGGGAG |
|
26081 |
GTTGGTTTCT |
GTAAATGGGA |
ACATATAGGG |
AGCACTGTCT |
GCACCTTGCT |
TTGAGAGCCG |
GTCATGACAG |
TTCCCATTGA |
|
26161 |
ACTGCCTTGT |
TCTTTCAATA |
GCTGCAGAGC |
AGGTGGCGGC |
AAGGAGAGGC |
AGCTAAGAGC |
CCAGACTTGG |
GAGCCAGACT |
|
26241 |
GCCTGGGTTT |
GAAACCCGGC |
TCTACCACTT |
ACTAGGCATG |
TGACCCTTGT |
GCTGTGCCTC |
AGTTTCTTCA |
TCTGTAAAGT |
|
26321 |
GGGGGCAAGA |
ACAGTCCCAA |
CTTCATAAGA |
TGGTTATACC |
ACCATGCCTG |
GCCAGATGAT |
TATAAAGTTT |
GAATGAGTTA |
|
26401 |
ATATTTGTAA |
AGCTCTTAGA |
ACAGTGCCTG |
GCAGATACTA |
GGTGCTCCTA |
AATGTTGGTT |
TTTATTATGT |
GGCTGGGTGG |
|
26481 |
CTCGGGGTTT |
TATTTAACAG |
CTCCCCTATT |
TACTAATAGA |
CATTTAGATC |
ATGTTCCATT |
TTCACTCTTA |
CAAACAGTTC |
|
26561 |
CACTTTGTGT |
GTGGCTCTGG |
GAACATGGGC |
CAGTGTCTCC |
CTAGGCCACA |
TTCCTAGAAA |
TAAGATTTCT |
TTTCTTTTTT |
|
26641 |
TTTTTTTTTT |
GAGACAGAGT |
CTCGCTTTAT |
CGCCAGGCTG |
GTGTGCAGTA |
GTGTGATCTC |
GGCTCACTGC |
AACCTCTGCC |
|
26721 |
TCCCGGGTTC |
AAGTGATTCT |
CCTGCCTCAG |
CCTCTCGAGT |
AACTGGGACT |
ATAGGCGCGC |
GGCACCACAC |
CCAGCTAATT |
|
26801 |
TTTGTATTTG |
TAGTAGAGAT |
GGGGTTTCAC |
CATGTTGGCC |
AGGATGGTCT |
CCATCTCTTG |
ACTTCGTGAT |
CCGCCCGCCT |
|
26881 |
CGGCCTCCCA |
AAGTGCTGGG |
ATTACAGGCG |
TGAGCCACTG |
AGCCCAGGCA |
GAAATAAGAT |
TTCTAGATCA |
AAGGATATAA |
|
26961 |
ATACTGTTTT |
GATAGATGTT |
GCCGAACTAA |
GGCCTGGGCT |
TTGAAGCCCA |
GGATGGGAAC |
AGCTGGGCTC |
GATGGGCAAA |
|
27041 |
GGGTTTGAGT |
GAAGGCATTC |
ATGGTGGGGA |
GTGGCTGGCA |
TGGCCAGTGC |
TGGGAGTGAT |
GTCCACCCTG |
TTCCTGGCCC |
|
27121 |
TGCTGACTCC |
TCTCCTGACC |
CCTCCAGGGA |
CCCAGCCTCC |
AACACTGCCC |
CGCTCCAGCC |
AGAGCAGCTC |
CAAGTGTTTG |
|
27201 |
AGACTCTGGA |
AGAGATCACA |
GGTGGGCTCT |
GTCTCTGCAT |
CCTGTTCTGC |
AGGGGCTGGG |
AGTCCTTGTC |
CTGTCCCCAC |
|
27281 |
TCCTTTAATC |
TCACCCTCTG |
CCTGCAGGTT |
ACCTATACAT |
CTCAGCATGG |
CCGGACAGCC |
TGCCTGACCT |
CAGCGTCTTC |
|
27361 |
CAGAACCTGC |
AAGTAATCCG |
GGGACGAATT |
CTGCACAAGT |
GAGCACTGAG |
AAAGAGGGGG |
CCTGATGGGG |
AGGAGTCCCA |
|
27441 |
GGGAGGAGTC |
CCTGTGGGAA |
GCTTTGGGCC |
TGAGGGAGTA |
CTCCTGTAGC |
AGTAACCTTT |
CCATGAAAGT |
CTGCAGAGTG |
|
27521 |
TGCTGGGGAT |
GGAGGAAGAT |
GAGAATAGCC |
TTTGCTGACC |
GGGAAGGGGT |
CCGTGGTAAG |
GTGCCCACCT |
TTCTCCCATA |
|
27601 |
GTGGCGCCTA |
CTCGCTGACC |
CTGCAAGGGC |
TGGGCATCAG |
CTGGCTGGGG |
CTGCGCTCAC |
TGAGGGAACT |
GGGCAGTGGA |
|
27681 |
CTGGCCCTCA |
TCCACCATAA |
CACCCACCTC |
TGCTTCGTGC |
ACACGGTGCC |
CTGGGACCAG |
CTCTTTCGGA |
ACCCGCACCA |
|
27761 |
AGCTCTGCTC |
CACACTGCCA |
ACCGGCCAGA |
GGACGAGTGT |
GGTAAGACAG |
GGAGCCCAGT |
GTGCGCACTC |
CCCATCTGCC |
|
27841 |
AGCACACAGC |
AGTGCCCAGG |
GGGCCCTGGC |
AGCAGCGTTC |
TTGGACTTGT |
GCAGACTGCC |
CGTCTCTGTG |
CACCCTTCTT |
|
27921 |
GACTCAGCAC |
AGCTCTGGCT |
GGCTTGGCCT |
CTTGGCATGG |
CTTCTCTAGC |
TGGGTCCTAC |
CTGCCTTGGC |
ATCCTTCCCT |
|
28001 |
CCCCCTCTGT |
TTCTGAAATC |
TCAGAACTCT |
TCCTCTCCCT |
ACATCGGCCC |
CACCTGTCCC |
CACCCCTCCA |
GCCCACAGCC |
|
28081 |
ATGCCCACAG |
CCAGTTCCCT |
GGTTCACTTG |
GACCTGGGGC |
CTCCCCTAAA |
AGTCCCCTGC |
GGTCCCTTCC |
TCCTCACTGC |
|
28161 |
AGTGGGCGAG |
GGCCTGGCCT |
GCCACCAGCT |
GTGCGCCCGA |
GGGCACTGCT |
GGGGTCCAGG |
GCCCACCCAG |
TGTGTCAACT |
|
28241 |
GCAGCCAGTT |
CCTTCGGGGC |
CAGGAGTGCG |
TGGAGGAATG |
CCGAGTACTG |
CAGGGGTATG |
AGGGGCGGAG |
GAGAGGGTGG |
|
28321 |
CTGGAGGGGT |
GCATGGGGCT |
CCTCTCAGAC |
CCCCTCACCA |
CTGTCCCTTC |
TCTCAGGCTC |
CCCAGGGAGT |
ATGTGAATGC |
|
28401 |
CAGGCACTGT |
TTGCCGTGCC |
ACCCTGAGTG |
TCAGCCCCAG |
AATGGCTCAG |
TGACCTGTTT |
TGGACCGGTG |
AGCTGCTGGC |
|
28481 |
GGGCTCAGAG |
CTGGGTGGAG |
GGGGGCAGCG |
AGGGGGATTG |
CCAGGGACTT |
GGCAGGATGG |
CGAGATGCAG |
TAGGGTGTGC |
|
28561 |
TATCTGGTAA |
AATATCCCTG |
GAGAGGGCTC |
AGCGCTCAGA |
CCTGAACAGC |
AACAGAGTGG |
CAGAAAAGGG |
GCCTGGGGGA |
|
28641 |
CACTGGGGCC |
CTTCAGACTA |
TGAAAAGGTT |
CTAAGGAGGT |
CTGTGTTGGT |
GGCTGTGACT |
GTGGCTGTGC |
TAGGGTGGTG |
|
28721 |
AGCCCTGTGG |
GCTCAGGCGT |
CAGACTACCT |
GGATTCAGAC |
CCAGCTCCTG |
CTTCCAACCT |
TGGTTTTTTA |
TTCCTAAAAT |
|
28801 |
GGGTATTGTA |
ATAATACCTA |
CCTTGCTGGG |
GTGTGGCAAG |
AATGAAATTA |
AACAGGGCTT |
GGCACAGTGA |
AGCACGGGAA |
|
28881 |
AGGCTTTCTA |
CAGAGCAGTG |
ACTGTTGTTA |
CTCGCTGTTA |
CACCTTAGGT |
AATGCGTTTT |
CCTCTCTGGG |
TGCCTCCCAT |
|
28961 |
TTTCTGGCTC |
AAGTCCCTGC |
CCAGGATCAA |
GCTTGGAGGA |
GGGCCCCGAG |
GGAGGGGCCA |
CAGAGACTGG |
GTGAAGAGCA |
|
29041 |
AGGGTGTTTG |
TCCCAGGAGC |
ATGGCGAAAA |
TTGCTGCTGG |
GTGGCCTTGG |
GAAGCACAAA |
GGGGACCCAA |
CTAAGGGCCT |
|
29121 |
GATCCTACTG |
CCCTGGGGGT |
GTCAGTGCCA |
GCCCCCCACA |
AATCTTTTCT |
GCCCCCCCCA |
GGAGGCTGAC |
CAGTGTGTGG |
|
29201 |
CCTGTGCCCA |
CTATAAGGAC |
CCTCCCTTCT |
GCGTGGCCCG |
CTGCCCCAGC |
GGTGTGAAAC |
CTGACCTCTC |
CTACATGCCC |
|
29281 |
ATCTGGAAGT |
TTCCAGATGA |
GGAGGGCGCA |
TGCCAGCCTT |
GCCCCATCAA |
CTGCACCCAC |
TCGTGAGTCC |
AACGGTCTTT |
|
29361 |
TCTGCAGAAA |
GGAGGACTTT |
CCTTTCAGGG |
GTCTTTCTGG |
GGCTCTTACT |
ATAAAAGGGG |
ACCAACTCTC |
CCTTTGTCAT |
|
29441 |
ATCTTGTTTC |
TGATGACAAA |
AATAACACAT |
TGTTAAAATT |
GTAAAATTAA |
AACATGAAAT |
ATAAATTAAT |
GCCCTAGCAG |
|
29521 |
TTCTATCCCC |
ACTGTTAATA |
ATTTGAAATA |
TTTTTCCTCT |
AGTTATTTTT |
GTCTGTGCAC |
ATTCTAATAT |
GTATATATAA |
|
29601 |
GTTAACATAT |
ATTAATATTA |
TTCTCCAGTT |
ATTTTTATCT |
GTGCACATTT |
TAACACACAC |
ACACACACAC |
ACACACACAC |
|
29681 |
ACATATGTAT |
TTTTAGACGG |
AGTTTCACTC |
TGTCGCCCAG |
GCTGGAGTGC |
AGTAGTACAA |
TCTTGGCTCA |
CTGCAGCCTC |
|
29761 |
CACCTCCTGG |
GTTTAAGCAA |
TTCTCCTGCT |
TCCGCCTCCT |
GAGTAGCTGG |
GATTACGGGA |
ACGTGCTACC |
TTGCCTGGCT |
|
29841 |
AATTTTTGTA |
TTTTTAGTAC |
ATAGGATTTC |
ACCATGTTGG |
CCAGGCTGGT |
CTCGAACCCC |
TGACCTCAGG |
TGATCTGCCA |
|
29921 |
GCCTCGGTCC |
CCCAAAGTGT |
TGGGATTACA |
GCGGTGAGCC |
ACCATGCCCA |
GTCATATATT |
TCTTTTTAAC |
AAATAGAATC |
|
30001 |
ATAGATCATA |
CATATTGTTT |
GCAAATTGCT |
TTTTCTCACT |
TTCCAGAACC |
TTGAAATGTT |
TTTCCATGTT |
CTAACATGGT |
|
30081 |
GATCTACCTT |
ATTCTTTTAA |
TTTTTCTTAT |
TTAGTTGTCT |
TTACACATGA |
AACACATGAA |
TACATCCTTG |
TGATAAACAT |
|
30161 |
TTTCAGTAAC |
ATAAAAGTAT |
AAATGTTACA |
AAGCCAACGT |
GCCCTTTCAC |
TCAACTCCCT |
GTCCACCCAG |
TCTCTCCTGT |
|
30241 |
CTGCTGGGAG |
AACCACCGCA |
TTGACTTGTG |
TGTTCACCCT |
TCCAGGCTCT |
TTTCTGCACA |
CTTATATAGA |
CATACTACAT |
|
30321 |
TTATATTAGG |
TCGAGTCAAA |
TAAGATTGCT |
GTTTGTGTAA |
ACCAAAAAGT |
GTCAAGAGCC |
TGGGCGCAGT |
GACTCACACC |
|
30401 |
TGTAATCCCA |
GCACTTTGGG |
AGGCTGAGGC |
AGGCAGATCA |
CTTGAGATCA |
GGAGTTCGAG |
ACCAATCTGG |
CCAACATAGC |
|
30481 |
GAGACCCCGT |
CTCTACTAAA |
AATACAAAAA |
CTAGCCAGGT |
GTGGTGATGC |
TGTTCTGCAC |
TTTGCTTTCC |
CCCCGACTTG |
|
30561 |
AGGTATCCTT |
TCTTGTGAGT |
ACAGACGGAT |
CTACCACCTT |
TATTTTTTTT |
TTAATTACTC |
AACCTGTAAC |
ATGGATGTAA |
|
30641 |
TTTCACTTTG |
TTTTTGAGGG |
ATATTGAGCT |
TGTTTCCCTG |
TTTTTGCAGT |
TTATTGCAAT |
TGAGCTCCAC |
ACACAAGTGA |
|
30721 |
GCCCTCTTTT |
GTATGCCCCC |
TAGTGGGAAT |
ACAGTGCTGG |
CAATGTTTAT |
CACAAGGATA |
TATTCATGCA |
TTTCAATTTA |
|
30801 |
AAGACAACTA |
AATGAGAAAA |
ATTAAAAGAA |
TATGGATCCA |
GGCTGGGCAT |
GGTGGCTCAC |
GCCTGTAATC |
CCAGCACTTT |
|
30881 |
GGGAGGCCGA |
GGCAGGCAGA |
TCACCTGAGG |
TCAGGAGTTC |
AAGACCAGCC |
TGGCCAACAT |
GGCAAAACCC |
CGTCTCTACT |
|
30961 |
AAAAATACAA |
AAATTAGCCA |
GGCGTGGTGG |
TGGGCGCCTG |
TAATCCCAGC |
TATTTGAGAG |
GTTGAGACAG |
GAGAATTGCT |
|
31041 |
TGAACCTGGG |
CAGCGGAGGT |
TGCAGTGAGA |
CGAGATTGCA |
CCAGTGCACT |
CCAACCTGGG |
CAACACAGTG |
CAACTCCTTC |
|
31121 |
TCAAGAAAAA |
AAAGAAAAAA |
AAAAAGAATA |
TGGGTCCAGA |
TCCATATGGA |
TCCTAGATCC |
AGATCACGGT |
GTTAGAACAT |
|
31201 |
GGAAAAACAT |
TGCAAGATTC |
TGCTAAGTGA |
AAAAAGCATT |
TGCAAACAGT |
ATGTACAGTC |
TATATTCAGA |
GGAGGAACTG |
|
31281 |
CTGGGTCATA |
GATGATATTT |
CATAGGTATT |
GCCAAACCGT |
TCTCTGGAGA |
AGTGGTATGG |
GTTTACCCTG |
GGATTCTTCT |
|
31361 |
ATGGAGGGAA |
TAGTTGAGCT |
CCCGGGCTTG |
CTCTTCTGGG |
TGCCCCTCCC |
CGCTTCCTAT |
CCACCACAAG |
GAGCTGCAGG |
|
31441 |
GGAGCGGGGC |
ATGCCGGTTC |
CTTGGCTGGA |
GAAGGAGTCT |
CCTTGTGAGG |
TGGTAGAAGG |
AGCACTGACG |
GCCTTGAGCC |
|
31521 |
CAGTTTCTGC |
CTTTGTCAAA |
TGGGGATAAT |
GACCCAGCCA |
CACCCCTCCC |
AGGGTTGTTG |
TGAGGCTGGA |
AAGGTGGTTC |
|
31601 |
CCAAGAGGGT |
GGTTCCCAGA |
ATTGTTGATG |
AGACTGTTTC |
TCCTGCAGCT |
GTGTGGACCT |
GGATGACAAG |
GGCTGCCCCG |
|
31681 |
CCGAGCAGAG |
AGCCAGGTTG |
GCCTGGACCC |
CAGGATGTAC |
CCTTCATTGC |
CCTTCACTCC |
CCCACTGGAT |
GCTGGGTGGT |
|
31761 |
CACTGCTGTA |
GGGAGGGGAC |
CCCCTGACAT |
ATGTCCCTTC |
CCACCCACTC |
TTCCACTGTG |
GAACCTCCTG |
TCATTTTCCA |
|
31841 |
CTTCACCAAG |
TGACAGAGGA |
CCTGCTCAGA |
TGCTGAGGGG |
AGGGGACTGC |
AAGGAAAGAT |
GGCTAGGAAA |
CCCAGTCCCT |
|
31921 |
CCACACCCTA |
GAGTAACTTG |
ATGCCTTGTG |
AGGGACACAG |
GCAAAGTTCA |
ATTCCTTGGA |
AGTCAAGGGA |
GACTGAGAAG |
|
32001 |
AGTACAGCTG |
CAGCACTGAG |
GGAGTGATGA |
ATTCTTAACT |
GGGGATGGTG |
GGAGGCTTCG |
AGTGGGAGGT |
GGCATTTGAG |
|
32081 |
CTAGGCTTTG |
AGAGAGGAGC |
AGGTATTGCA |
CTTGCATTTA |
GGTAGAAAGC |
ATTGGGGTGC |
AAGGTGACAC |
TGGAGGGGGA |
|
32161 |
GGCATCAGGA |
AATCCAGGAT |
GTCTTCAAAG |
TTCTGGTGTC |
GGGGGCTGTT |
GAGTAAGCAC |
AGGAATAAGG |
GGGTCAAGTT |
|
32241 |
AGAGTCAGGG |
TGGGGTCTGA |
CCTGGATGCC |
ATAGGACCTG |
ATCCCCAAGC |
CACAGGGTGG |
GACTTGACTG |
GGCAGTGGGG |
|
32321 |
ACCTTTGGAA |
AGGACTTTGG |
GGAGAAAAAC |
AGACTGGAGT |
CTGTCTTAGG |
CGATCATCGG |
TCCGTGAAAT |
GAGCATGTGT |
|
32401 |
TACAGGCTTG |
GTATGTACCA |
GACCCTGTGC |
TAAGCAAGGG |
GGTATGGAGA |
GGAGAGGGTG |
ACAAGAATAT |
TGGATCAACA |
|
32481 |
CCCGGGAGCT |
CCATCTATCC |
CAGGATGCAC |
TATCTTTTTT |
TTATTTTTTT |
GAGACGGAGT |
CTCACTCTGC |
CTGCAGGCTG |
|
32561 |
GAGTGCAGTG |
GCTCCATCTC |
GGTTCACTGC |
AACCTCTGCC |
TCCTGGGTTC |
AAGCGCTTCT |
TGTGCCTCAG |
CCTCCCAAGT |
|
32641 |
AGCTGGGATT |
ACAGGCACAT |
GCCACCACAC |
CCAGCTAATT |
TTTGTATTTT |
TAGTAGAGAC |
GGGGTTTCAC |
CATGTTGGCC |
|
32721 |
AGGATGGTCT |
CGATCTCTTG |
ACCTCAAGAT |
CCGCCCACCT |
TGGCCTCCCA |
AAGTGCTGGG |
ATTACAGACA |
TGAGCCACCG |
|
32801 |
TGCCCAGCCA |
GATACGCTAT |
CTTTTTATTG |
AGTGATTGAG |
ACAGGGTCTT |
GCTCTCTTGT |
CCAGTCTTGA |
ATGTGGTGGT |
|
32881 |
GTAATCACAG |
GCTCACTGCA |
GCCTTGACCT |
CCTGGGCTCA |
AGTTACCCTT |
CTGCAGTAGC |
TGGGACTATA |
GGAGCGTGCC |
|
32961 |
ACCACGCCTG |
GGTAATTTAA |
AAAATTTTTT |
TTGTATAGAC |
AGGGTCTCAC |
TATGTTGCCC |
GAGCTGGTCT |
CAAACTCGTG |
|
33041 |
GGCTCAAGTG |
ATCCTCCAGT |
TTTGGCCTCC |
CAAAATGTTG |
GGATCACAGG |
AGTGAGCCAC |
CACTCCTGGC |
GATGAGCCAA |
|
33121 |
GTCTTTTTTT |
TTTTTTTTTT |
TTTTTGATAT |
GGAGTCTTGC |
TCTGTTGCCC |
AGGCTGGAGT |
GCAATGACAC |
GATCTTGGCT |
|
33201 |
CACTGCAACC |
TCTGCCTCCC |
AGGTTCAAGC |
AGTTCAAGCA |
ATCCTCCTGT |
CTCAGCCCCC |
CAGTAGCTGG |
GATTACAGGC |
|
33281 |
ATGCGCTACC |
ACGTCCGGCT |
AATTTTTGTA |
TTTTTAGTAG |
AGATGAGGTT |
TTGCCATGTT |
GGCCAGGCTG |
GTCTTGAACT |
|
33361 |
GCTGACCTCA |
GGTGATCCAC |
CTGCCTCGGC |
CTCCCAAAGT |
GCTGGGATTA |
CAGGTGTGAG |
CCATCGTGCC |
TGGCGGAGCC |
|
33441 |
GAGTCTTAAA |
AGATGACCCT |
GTGGAGAAAT |
GGTGGTCCAG |
GCTGAAGGGA |
CAGCCTATGC |
AAACACTGGG |
AGGTGTGGAA |
|
33521 |
AATCATGACC |
TGTGGGTGGA |
AATTTTGGCT |
AGAACATCAA |
AATCATCAGG |
TGTACATTCC |
TGTACCCATG |
CAGCAGTCAG |
|
33601 |
AATCTCTGGG |
GGTGGGGCCC |
CAAAATTGTA |
TGCATACAGA |
CTGTGTGCTG |
ATTTGTGATA |
TTACTTAGGA |
TTTTTTGACT |
|
33681 |
TTACAATGGT |
GGAAAAGCAA |
TAATATACAT |
TCAGTATAAA |
CCGTACTTTG |
AATACCCATA |
CAGCCATTCT |
GTTTTTCACT |
|
33761 |
TTTATTTTTA |
TTTATTTATT |
TATTTATTAT |
TTATTTTGAG |
ATGTCATTTT |
GCTGTTGTTA |
CCCAGGCTGG |
AGTGCAATGG |
|
33841 |
CGCAGTCTTG |
GCTCACCGCA |
ACCTCCACCT |
CTCAGGTTCA |
AACGATTCTC |
CTGCTTCAGC |
CTCCAGAGTG |
GCTGGGATTA |
|
33921 |
CAGGCAGGCA |
CCACCACACC |
CGGCTAATTT |
TGTATTTTTA |
GTAGAGACGG |
GGTTTCTCCA |
TGTTAGTCAG |
GCTGGTCTCG |
|
34001 |
AACTCGAGAG |
CTCAGGTGAT |
CTGCCCATCT |
CAGCCTCAAG |
CCACCATGCC |
CAGCCCTACT |
TTCAGTATTC |
AATAAATTAC |
|
34081 |
ATAGCCAGGC |
ACCGTGGCTC |
ACACCTGTAA |
TCCCAGCACT |
TTAGGAGGCC |
AAGGTGGGAG |
GATCCTTTGA |
GGCCAGAAGC |
|
34161 |
TCGAGACCAG |
CCTGGGCAAC |
ATAGTGAGAC |
CCCATTTCTA |
CAAAAAATAA |
AAAAACTAGC |
TGAGTGTGGT |
GGCGTGTGTC |
|
34241 |
TGTAGTCCCA |
GCTACTTGGG |
CAGCTGAGGT |
GGAAAGACTG |
CTTGAGCCCA |
GAGGTCAGGG |
CTGCAGTGGG |
CCATGATCTC |
|
34321 |
ACCACTGCAC |
TCAGCCTGGG |
CAACACAGCA |
AGGCCCTGTC |
TCAAAAATAA |
ATAAATAAAT |
AACACAAACT |
TATTTAACAG |
|
34401 |
TTTACTATAA |
AATAGGCTTT |
GTGTCAGATG |
ATTCTGCCCA |
ACTGTAAGCT |
GCTGGCAGTG |
TAAATGTTCT |
GAGCACGTGT |
|
34481 |
AAGCCAGGCT |
AGGTGTCTTA |
AATGCATTTT |
CAGTTTCAAC |
TTAGAATTGG |
TTTATCAGGA |
CGTAGCCCCT |
TGGTGTTGAG |
|
34561 |
GGGCATGTGT |
ATTAACAGTC |
TCCTTAGTGA |
CTTTTTTTTT |
TTTGAGATGG |
AGTCTTGCAC |
TGGCCGTAGT |
GCAGTGGCAC |
|
34641 |
AATCTCAGCT |
CACTGCAACC |
TCTTGTCTCC |
CGGGTTCAAG |
CGATTCTCCT |
GCCTCAGTCT |
CCCAAGTAGC |
TGGGATTACA |
|
34721 |
GGCACCCACA |
CCACGCCCAG |
CTAATTTTTG |
TGTGTGTGTA |
TTTTTAGTAG |
AGACGGGGGT |
TTCACTATGT |
TGGCCAGGCT |
|
34801 |
GGTCTCGAAC |
TCCTGACCTT |
GTGATCTGCC |
CACCTCAGAC |
TCTCAAAGTG |
CTAGGATTCC |
AGGCATGAGC |
CACCGCGCCC |
|
34881 |
AGAGTCCTTA |
GTGATTTTTA |
CACCATGAAT |
TGTTGAAGCC |
CTAAGCCAGA |
GCCAAGGGCA |
AGAGTATAGA |
GAATCTGGAG |
|
34961 |
ATGCGGAGAG |
GGTTCTGATT |
GCCTACAAGG |
AGTTTGGACT |
TTATTGTGGA |
GGCAGCGGGG |
AGCCAAGGCA |
GGTTTTAGAG |
|
35041 |
TAGGAGAGGG |
TCCAAGCCTG |
TGGGTCACCC |
TTCCGACTTC |
CCTTTCCGAA |
TGCCAAACAC |
CTTCATGTCC |
CCCGTGGGCC |
|
35121 |
CCCTTTGTCC |
CTCCCACCCC |
AAACTAGCCC |
TCAATCCCTG |
ACCCTGGCTT |
CCGCCCCCAG |
CCCTCTGACG |
TCCATCATCT |
|
35201 |
CTGCGGTGGT |
TGGCATTCTG |
CTGGTCGTGG |
TCTTGGGGGT |
GGTCTTTGGG |
ATCCTCATCA |
AGCGACGGCA |
GCAGAAGATC |
|
35281 |
CGGAAGTACA |
CGATGCGGAG |
ACTGCTGCAG |
GAAACGGAGG |
TGAGGCGGGG |
TGAAGTCCTC |
CCAGCCCGCG |
TGGGGTCTGC |
|
35361 |
ACCGGCCCCC |
GGCACTGACC |
CACCACCCCC |
TCACCCCAGC |
TGGTGGAGCC |
GCTGACACCT |
AGCGGAGCGA |
TGCCCAACCA |
|
35441 |
GGCGCAGATG |
CGGATCCTGA |
AAGAGACGGA |
GCTGAGGAAG |
GTGAAGGTGC |
TTGGATCTGG |
CGCTTTTGGC |
ACAGTCTACA |
|
35521 |
AGGTCAGGGC |
CAGGTCCTGG |
GGTGGGCGGC |
CCCAGAGGAT |
GGGGGCGGTG |
CCTGGAGGGG |
TGTGGTCGGC |
AGTTCTGATG |
|
35601 |
GGAGGGGCAA |
GAGCTGGAGG |
CAGTGTTTGG |
GGGAGGGCAG |
TTACAGCGGA |
GAAGGGAGCG |
GGGCCAAGCC |
CTAGGGTGGT |
|
35681 |
GAAGGATGTT |
TGGAGGACAA |
GTAATGATCT |
CCTGGAAGGC |
AGGTAGGATC |
CAGCCCACGC |
TCTTCTCACT |
CATATCCTCC |
|
35761 |
TCTTTCTGCC |
CAGGGCATCT |
GGATCCCTGA |
TGGGGAGAAT |
GTGAAAATTC |
CAGTGGCCAT |
CAAAGTGTTG |
AGGGAAAACA |
|
35841 |
CATCCCCCAA |
AGCCAACAAA |
GAAATCTTAG |
ACGTAAGCCC |
CTCCACCCTC |
TCCTGCTAGG |
AGGACAGGAA |
GGACCCCATG |
|
35921 |
GCTGCAGGTC |
TGGGCTCTGG |
TCTCTCTTCA |
TTGGGGTTTG |
GGGAGATATG |
ACTCCCGCAA |
ACCTAGACTA |
TTTTTTTGGA |
|
36001 |
GACGGAGTCT |
TGCTCTGTCA |
CCCAGGCTGG |
AGTGCAGTGG |
CGTTATCTCG |
GCTCACTGCA |
ACCTCCACCT |
CCTGGACTCA |
|
36081 |
AGCGATTTTC |
ATGCCTCAGG |
CTCCTGAGTA |
GCTGGGATTA |
CAAGCGCCCG |
CTAATTTTTT |
TTTTTTTTTT |
GAGACAGAGT |
|
36161 |
CTCGCTCTGT |
CACCCAGGCT |
AGAGTGAAAT |
GGTGCGGTCT |
CAGCTCAGCC |
TCCCAGGTTA |
AAGCGATTCT |
TCTCCCTCAG |
|
36241 |
TCTCCTGAGT |
AGCTGGGATT |
ACAGGCGCGA |
GCCACCACGC |
CCGGCTAATT |
TTTGTATTTT |
TAGTAGAGAT |
GGGATTTCAC |
|
36321 |
CATGTTGGCC |
AGGTTGGTGT |
CAAACTCCTG |
ACCTCATGAT |
CCGCCCGCCT |
CGGCCTCCCA |
AAGTGCTGGG |
ATTACAGGTG |
|
36401 |
TGAGCCACCG |
TGCCCGGCCT |
AATCTTTGTA |
TTTTTAGTAG |
AGACAGGGTT |
TCACCATGTT |
GTCCAGGCTG |
GTACTTTGAG |
|
36481 |
CCTTCACAGG |
CTGTGGGCCA |
TGGCTGTGGT |
TTGTGATGGT |
TGGGAGGCTG |
TGTGGTGTTT |
GGGGGTGTGT |
GGTCTCCCAT |
|
36561 |
ACCCTCTCAG |
CGTACCCTTG |
TCCCCAGGAA |
GCATACGTGA |
TGGCTGGTGT |
GGGCTCCCCA |
TATGTCTCCC |
GCCTTCTGGG |
|
36641 |
CATCTGCCTG |
ACATCCACGG |
TGCAGCTGGT |
GACACAGCTT |
ATGCCCTATG |
GCTGCCTCTT |
AGACCATGTC |
CGGGAAAACC |
|
36721 |
GCGGACGCCT |
GGGCTCCCAG |
GACCTGCTGA |
ACTGGTGTAT |
GCAGATTGCC |
AAGGTATGCA |
CCTGGGCTCT |
TTGCAGGTCT |
|
36801 |
CTCCGGAGCA |
AACCCCTATG |
TCCACAAGGG |
GCTAGGATGG |
GGACTCTTGC |
TGGGCATGTG |
GCCAGGCCCA |
GGCCCTCCCA |
|
36881 |
GAAGGTCTAC |
ATGGGTGCTT |
CCCATTCCAG |
GGGATGAGCT |
ACCTGGAGGA |
TGTGCGGCTC |
GTACACAGGG |
ACTTGGCCGC |
|
36961 |
TCGGAACGTG |
CTGGTCAAGA |
GTCCCAACCA |
TGTCAAAATT |
ACAGACTTCG |
GGCTGGCTCG |
GCTGCTGGAC |
ATTGACGAGA |
|
37041 |
CAGAGTACCA |
TGCAGATGGG |
GGCAAGGTTA |
GGTGAAGGAC |
CAAGGAGCAG |
AGGAGGCTGG |
GTGGAGTGGT |
GTCTAGCCCA |
|
37121 |
TGGGAGAACT |
CTGAGTGGCC |
ACCTCCCCAC |
AACACACAGT |
TGGAGGACTT |
CCTCTTCTGC |
CCTCCCAGGT |
GCCCATCAAG |
|
37201 |
TGGATGGCGC |
TGGAGTCCAT |
TCTCCGCCGG |
CGGTTCACCC |
ACCAGAGTGA |
TGTGTGGAGT |
TATGGTGTGT |
GATGGGGGGT |
|
37281 |
GTTGGGAGGG |
GTGGGTGAGG |
AGCCATGGCT |
GGAGGGAGGA |
TGAGAGCTGG |
GATGGGGAGA |
ATTACGGGGC |
CACCTCAGCA |
|
37361 |
TGTGAAGGGA |
GGGAAGGGGC |
TGCCTGTGCC |
CCACCTTGCA |
GGGTCTGTGC |
ACTTCCCAGG |
ATTAGGGAAA |
GACCGGGTAG |
|
37441 |
GGTCTGTCTC |
CTGGCATCAC |
ATCTCCCCCT |
GCTACCTGCC |
ATGATGCTAG |
ACTCCTGAGC |
AGAACCTCTG |
GCTCAGTACA |
|
37521 |
CTAAAGCTCC |
CTCTGGCCCT |
CCCACTCCTG |
ACCCTGTCTC |
TGCCTTAGGT |
GTGACTGTGT |
GGGAGCTGAT |
GACTTTTGGG |
|
37601 |
GCCAAACCTT |
ACGATGGGAT |
CCCAGCCCGG |
GAGATCCCTG |
ACCTGCTGGA |
AAAGGGGGAG |
CGGCTGCCCC |
AGCCCCCCAT |
|
37681 |
CTGCACCATT |
GATGTCTACA |
TGATCATGGT |
CAAATGTGCG |
TGGCTGAGCT |
GTGCTGGCTG |
CCTGGAGGAG |
GGTGGGAGGT |
|
37761 |
CCTGGGTGGA |
GGAGCCCACA |
AGGGGCATGA |
AAGGGGACCA |
GGATGTATGT |
AGACCCAGGA |
GCCCTAGTAT |
GTTAGGAGCC |
|
37841 |
TCAAAACCTT |
CTTGTATCCC |
TTTTACAGTC |
AAAGTCCAAA |
GCCACTCTTG |
AGGAACACTC |
TTGTACAAAA |
TTAAGCTGGG |
|
37921 |
CACAGTGGCT |
CATGCCTGTA |
ATCCCAGTAC |
TTTTGGAGGC |
TGAGGTGGGA |
GGATCCCTTG |
AAGCCAGGAG |
TTCAAGACCA |
|
38001 |
GCCTGGGCAA |
CATAGTGAGA |
TCCTATCTCT |
ACAAAAAATA |
AAAAAATTAT |
CTGGGTGTGG |
TGGTGTGTGC |
CAGTAGTCCC |
|
38081 |
AGCTACTCAG |
GAGAGGCTGA |
GGCAGGAAGA |
TCACTTGAGC |
CTAGTTTAAG |
GTTGCAGTAA |
GCTATGATTG |
CACCACTGAA |
|
38161 |
ATCCAGCCTG |
GGTGACAGAG |
CGAAACCTCA |
TCTCAAAAAA |
ATAAAAAAGC |
AAACAAAAAG |
AAAAAAAAAA |
TTAAAAGGGA |
|
38241 |
AACTAGAAGA |
GATGCCAAAG |
GTTCTGGCTG |
AAGACCCCAG |
AGTCTGGTGC |
TACTTCTCTA |
CCACCTGAGG |
GCTTTGGGCT |
|
38321 |
GTCCCTTGGG |
ACTGTCTAGA |
CCAGACTGGA |
GGGGGAGTGG |
GAGGGGAGAG |
GCAGCAAGCA |
CACAGGGCCT |
GGGACTAGCA |
|
38401 |
TGCTGACCTC |
CCTCCTGCCC |
CAGGTTGGAT |
GATTGACTCT |
GAATGTCGGC |
CAAGATTCCG |
GGAGTTGGTG |
TCTGAATTCT |
|
38481 |
CCCGCATGGC |
CAGGGACCCC |
CAGCGCTTTG |
TGGTCATCCA |
GGTACTGGGC |
CTCTGTGCCC |
CATCCCTGCC |
TGTGGCTAAG |
|
38561 |
AGCACCCTCC |
TGCAGAGGGT |
GGGAAGGAGA |
GATGAGTCCA |
GTATGCCAGG |
CCCCTCACGG |
AAGGCTGCAT |
GCTGGGCTGG |
|
38641 |
GGAGGGGCCA |
CCATCCTGCC |
TCTCCTTCCT |
CCACAGAATG |
AGGACTTGGG |
CCCAGCCAGT |
CCCTTGGACA |
GCACCTTCTA |
|
38721 |
CCGCTCACTG |
CTGGAGGACG |
ATGACATGGG |
GGACCTGGTG |
GATGCTGAGG |
AGTATCTGGT |
ACCCCAGCAG |
GGCTTCTTCT |
|
38801 |
GTCCAGACCC |
TGCCCCGGGC |
GCTGGGGGCA |
TGGTCCACCA |
CAGGCACCGC |
AGCTCATCTA |
CCAGGGTCAG |
TGCCCTCGGT |
|
38881 |
CACACTGTGT |
GGCTGTCTGC |
TTACCTCCCC |
CAACCCCGGT |
GGACTAGGGT |
CCCTTTCTCT |
GATGTTCCCT |
CAACTGTCAC |
|
38961 |
CTCTCAAGGA |
AACCCCATTA |
TCCCTACAAA |
AAATTCTTAC |
TGCCTTCCAA |
CCCCTGTGAC |
CCCATTCTCT |
CCACGGTGAC |
|
39041 |
TGTGTCATAC |
CCCAAAGGTG |
ACCTCTGTTT |
TTCTCCTGTG |
ACCCTGTCAC |
CTTCCATGGA |
GTCCCCATCC |
CAGATCCGTG |
|
39121 |
AGTGACCCCC |
ATCATGACTT |
TCTTTCTTGT |
CCCCAGAGTG |
GCGGTGGGGA |
CCTGACACTA |
GGGCTGGAGC |
CCTCTGAAGA |
|
39201 |
GGAGGCCCCC |
AGGTCTCCAC |
TGGCACCCTC |
CGAAGGGGCT |
GGCTCCGATG |
TATTTGATGG |
TGACCTGGGA |
ATGGGGGCAG |
|
39281 |
CCAAGGGGCT |
GCAAAGCCTC |
CCCACACATG |
ACCCCAGCCC |
TCTACAGCGG |
TACAGTGAGG |
ACCCCACAGT |
ACCCCTGCCC |
|
39361 |
TCTGAGACTG |
ATGGCTACGT |
TGCCCCCCTG |
ACCTGCAGCC |
CCCAGCCTGG |
TATGGAGTCC |
AGTCTAAGCA |
GAGAGACTGA |
|
39441 |
TGGGCAGGGG |
AGGTGGGACC |
TTCAGCCCAG |
GGTCCACTGT |
GGGGGCAGAG |
GGAGTGGCAG |
AGACACCGGG |
GTTCCTTCCC |
|
39521 |
CTAATGGGTC |
ACCTTCTCTT |
GACCTTTCAG |
AATATGTGAA |
CCAGCCAGAT |
GTTCGGCCCC |
AGCCCCCTTC |
GCCCCGAGAG |
|
39601 |
GGCCCTCTGC |
CTGCTGCCCG |
ACCTGCTGGT |
GCCACTCTGG |
AAAGGCCCAA |
GACTCTCTCC |
CCAGGGAAGA |
ATGGGGTCGT |
|
39681 |
CAAAGACGTT |
TTTGCCTTTG |
GGGGTGCCGT |
GGAGAACCCC |
GAGTACTTGA |
CACCCCAGGG |
AGGAGCTGCC |
CCTCAGCCCC |
|
39761 |
ACCCTCCTCC |
TGCCTTCAGC |
CCAGCCTTCG |
ACAACCTCTA |
TTACTGGGAC |
CAGGACCCAC |
CAGAGCGGGG |
GGCTCCACCC |
|
39841 |
AGCACCTTCA |
AAGGGACACC |
TACGGCAGAG |
AACCCAGAGT |
ACCTGGGTCT |
GGACGTGCCA |
GTGTGAACCA |
GAAGGCCAAG |
|
39921 |
TCCGCAGAAG |
CCCTGATGTG |
TCCTCAGGGA |
GCAGGGAAGG |
CCTGACTTCT |
GCTGGCATCA |
AGAGGTGGGA |
GGGCCCTCCG |
|
40001 |
ACCACTTCCA |
GGGGAACCTG |
CCATGCCAGG |
AACCTGTCCT |
AAGGAACCTT |
CCTTCCTGCT |
TGAGTTCCCA |
GATGGCTGGA |
|
40081 |
AGGGGTCCAG |
CCTCGTTGGA |
AGAGGAACAG |
CACTGGGGAG |
TCTTTGTGGA |
TTCTGAGGCC |
CTGCCCAATG |
AGACTCTAGG |
|
40161 |
GTCCAGTGGA |
TGCCACAGCC |
CAGCTTGGCC |
CTTTCCTTCC |
AGATCCTGGG |
TACTGAAAGC |
CTTAGGGAAG |
CTGGCCTGAG |
|
40241 |
AGGGGAAGCG |
GCCCTAAGGG |
AGTGTCTAAG |
AACAAAAGCG |
ACCCATTCAG |
AGACTGTCCC |
TGAAACCTAG |
TACTGCCCCC |
|
40321 |
CATGAGGAAG |
GAACAGCAAT |
GGTGTCAGTA |
TCCAGGCTTT |
GTACAGAGTG |
CTTTTCTGTT |
TAGTTTTTAC |
TTTTTTTGTT |
|
40401 |
TTGTTTTTTT |
AAAGATGAAA |
TAAAGACCCA |
GGGGGAGAAT |
GGGTGTTGTA |
TGGGGAGGCA |
AGTGTGGGGG |
GTCCTTCTCC |
|
40481 |
ACACCCACTT |
TGTCCATTTG |
CAAATATATT |
TTGGAAAACA |
GCT |
|
|
|
|
|
|
|
|
|
|
|
|
>ref|Gene_ID:2064|ERBB2|NC_000017.10:37844392...37884914 (+)
AGTTCCCGGATTTTTGTGGGCGCCTGCCCCGCCCCTCGTCCCCCTGCTGTGTCCATATATCGAGGCGATAGGGTTAAGGG
AAGGCGGACGCCTGATGGGTTAATGAGCAAACTGAAGTGTTTTCCATGATCTTTTTTGAGGTAGGGCTGTTTACTGTCAC
CACCCCTGTCGGATTTTACTTCCTAAACGTACCTGTAACTATCCACTTCTCTCCATCTCTTCTGGCACCACCCTGGTTAA
AGACACCATCATGTGTCGCCAAGACAGCCGCAGTAGCTTCTTAATGGCTCTCCCTGCCTCTACTTTTGCCTCTTCCAACC
TGCGCTCCATTTTGAAAAATTAAAATTTGCCCATATCACTTTTTTTTTCTTAAAATTATTTACTGGCTCCCAATTACCTT
GGGTAAAATACAGTCTCCACAAACCCTGCCTGATTTGGCCCCTGTCCACTGGTCTCCCTCACTCCCTTGCTCCAGACCCG
CTTCAGAGGGCTATGTCCCTCAAGCTTCCTGACTGCCTGGCCTGGTCTGAATCACTCACTCTTCTTTTTTCTTCTAGTCG
CAATTGAAGTACCACCTCCCGAGGGTGATTGCTTCCCCATGCGGGGTAGAACCTTTGCTGTCCTGTTCACCACTCTACCT
CCAGCACAGAATTTGGCTTATGGTAGGCGCTAACTGCGTTTGTTTGTTCTTCTGTTTAATGAATGAACAGCATACATCAA
CATAAGAACTTGACAAATCCAGGGCTGTAAAATCATCAGTATGGTTCTGCACTGAGATCGGAGAGAAGTAATATTTCTAG
GAAAATTAGGAACCCTGGGAACAGGACGCTTGCTTTAGTATCCTCTCCCTGCTCACCTCCCCTGCACTCCCATCAGCACC
GACCCACACCCAATCTCATAGAAGCCTTGTAGCTAAGGATCACCCTTTCTCCTCCCCCACTCTCCTCACCCCTTGTCAAC
TTTTCTTTTTCGTCCTGGGGGTTGGAATGAGTAAGAAGTAGCCTGGGATTCCATTCACTCACTTAACAAACATTTCTGAG
TCCTTAGCTCTAGCACCTTGCTAAGCAAGGCAAAATCTCCAGGAGGCACCATTCACATTGCATTTTCTGTGAATGGTGCT
CTGGGGAGCAGCATTCACATTGCCTTTTCTGTGAATGGCAAATTCTTCCAGTTAAATATAACATGAATAGTGTCCCCTGG
AGTTGACCACCCAACTGATACTGACTGAGAAGCTGAAATGAACAAAACAACCCCTTAGCCCTCCAGGAGCTGACCGGAAA
TCCAGTGCTAATACTACTTTGCATCTTACAGATTAGTTCTTTTACAATACTGTTTTTTTTTCTTTTTTCATTTCATTTTG
TCCTTTCTGTGACTCTGGGATGAGTCTTTTTATGAGGATCCTCATATAAAGATGGACATTTAGGATTAAAGAGGATGAAA
TCCTGACAAAATAGGGAGTCTCCCCTTTAGAAAATTCCTAAGTAAGGCTGGGGGTGGTGGCTCACGCCTGTAATCCCAGC
ACTTTGGGAGGCCGAGGCGGACGGATCACCTGAGGTTAGGAGTTTGAGACCAGCCTGACCAACATGGAGAAACCCCATCT
CTACTAAAAATACAAAATTAGTTGGGTGTGGTGGTGCATGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAAT
CGCTTGAACCCAGGGAGGCAGAGGTTGTGGTGAGCCAAGATTGCGCCATCGCACTCCAGCCTGGGCAACAAGAGCGAAAC
TCAAAAAAAAAAAAAAAAAGAAAAAGAAAATTCCAATTTTGAAGGCCTCATCCTATATTATGTCAAACATACTGAAATGC
AGTAACGCCCCACATTAAATAAGATTTATAAATAACTATACATATATATAATTCAATCTAATTGCTGTTAATAGTTGACA
TATTGCTACATTTATATACATTTAGTTAAAAAAAATTTTTTTTCCCAGACAGCCTCTCACTCTTTCACCTAGACTGAAGT
GCAGTGGCATGATCACGACTCACTGCAACCTCAACCTCCCAGACTCAAGTGATCCTTCCATCTCAGCCTCCTGAGTAGCT
GGGACTGCAGCATGCGCCACTATGCCCTGCTAATTTTTTTAATTTTTTGTAGAGACACGGTCTTGCTATGTTGCCTAGAC
TGGTCTCCAATTCCTGGGCTCGAGTGATCCTCCCGCCTCAACCTCCCAAAGTGCTGGGATTACGGGCGTGAGCCATGCCA
CACGGCCATAAAATATTAATTTTCGCAGCTTTCTTATATTTTAGAACTAACAATGGAAATTTGTTCGGGTCTAAAGTATT
TCAGAGGTCCTTGAAAACCCATGCCTACATACCTGATGGAAAAAGCAATCCTAGGTTAATGGTGGAAGTGGGAGTAGAGA
CTTCTGTTCTGTTGACTTCTTGGAAGATGGGGTACTGTCTCTCTGGGACAGCTCTTGAGAATTTCCCTGCCAGCACAGCC
CCAGATAACAATCTCTAGATGGCGATTACCTGGCCTCTCTTCCCAACTTTCTAGCCTGGAGCCCCTAGTTCTCCCCTGAG
CCTCCTTAGCTTGTCCTTCTTCCTAACTTGTATTTGGCTTCAGATGTGATCCACAGTCTGAAAAGTCACTAATTCATTCC
TTCAACTCAGGCTTATTGAGTCCTCCTGTGTATCAGCCATTGTACTCATGGGGGAAAAAAAAGACAAAGCATATGTTAAT
AGTAGAGTGTGCTGGACAGGCACAGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGGCGAGGCAGGTGGATCATCTG
AGGTCAGGAGTTCGAGACCAGCCTGACCTAACATGGAGAAACTCCTGAGATCGTGCCATTGCACTCCAGCCTGGGCAACA
AGAGCAAAACTCCGTTTCAAAAAAAAAAAAAAAAGTATAGTGTGCTAAAGGCTCAACGGCAAGCTGACCATGTTCTTAGA
TCAAAATTGGTAGAGAGTCTACAATGTGGGTTCCTTATTCATCAAATGTTTATTAAGTTTACCATGTGCAAGTCTCTGGG
AACAGAGTGATGAACAAGGCACTGTACTTTTCATGGTCAGAGGAGGGAAACAGGCCATAAACAAGTGTCAAACAAAAGAC
TGAAGCCAGGTGCGGTGGCTCACATCTGTAATCCCAGCACTGTGGGAGGCCAAGGCAGGCGGATCATGAGATCAGGAGAT
CGAGACCATCCTAGCCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAAAATTAGCTGGGCATGGTGGCACGTGC
CTGTAATCCCAGCTACTCCGGAAGCTGAGGCAGGAGAATTGCTTGAACCAGGGAGTTGGAGGTTGCAGTGAGCCTGGATT
ATGCCACTGCACTCCAGCCTGGTGACAGAGCGAGACTCCATCTACATTAAAAAAAAAAATATATATATATATATATACAC
ACACACACACACACACACACACATACCCTCTAACCCAGGAATTTCACTCCTAGGTATACCTACATAAGCTCCAGTATACC
TAAACAAGTGCAAATTTGTTTAAGTACAGTTATTTGTGGTAGCATTAGTCATTGTTTTCAATAGCAAGAAGAAAAAGGAA
ACAACTAAATGTCCATCAATAGGGAATGAATTATATTAATGGAGGGAGAGCCATACAATGGAAGGCTGAACAGAAATTAA
TAGGAATGGGGCAGATTTGTAATGTACTAGCATGGTAAAACCTTCATGATAGATATAGATATAGATATAGATATAGATAT
AGATATATATACATATACATATACATATACATATACATATATATATATATATATATATATCTCTTGTGTCTCAGCCTCCC
GAGTAGCTGGGATTACAGGTGTGTGCCACCACATCCGGCTAATTTTTGTATTTTTTAGTAGAGACAGGGCTTCACCATGT
TGGTAAGGCTGTCTTGAACTCCCGACCTCAGGTGATCCACCTGTCTCAGCCTCCCAAAGTGCTGGGATTATAGGCATGAG
CCATCACACCTGGCCAAATATTTTTGATAAGTATCAAGTGCACAGTGCAGAACAAAATATGTGTGTGTGTATGCATGTGT
ATGTACACCTATACACTTATATACAGTACCCCATGTGAAGAAAAATAAGGGTACGTGTTATGCGCGTAGTATTATGGTTG
TTATTTTTGAGAATATATCTAGAAAGATAAAAAAGAAAGTGGAAATAGTTCTTGCCTCTGGTGGGAAGTGGGACTATGTG
CCTGATCAATAGGGAAGTAAGGAACACTTTTTTTTTTTTTTTTTAAACGGAGTTTTTGCTCTTGTTACCCAGGTTGGAGT
GCAATGGCGCGATCTTAGCTCACTGCAACCTCTGCCTCCCAGGTTCAAGCGATTCTGCTGCCTCAGCCTCCTGAGTAGCT
GGGATTATAGGCATGCGCCTCCACGCCTGGCTAATTTTGTATTTTTAGTAAAGATGGGGTTTCTCCATGTTGGTCAGGCT
GGTCTTGAACTCCCCACCTCAGGTGATCCGTCCGCCTCAGCCTCCCAAAGTGCTAGGATTACAGGCGTGAGCCACCGTGC
CTGGCCAGGAACGCTTTTTATTTTTGTACCTTTAAAAGTGTGTACCGTCTGTGTATATAATCAGTTAAAAACAAAGAAAA
GCTGAGTGTGGTGGCTCATGCCTGTAATCCCAGCCCTTAAGGAGGCCGAGGCCGGCGGCAGATCACCTGAGGTCAGGAGT
TCAAGACCGGCCTGACCAAAACGGTGAAAACTCATCTCTACAAAAACATAAAAATTAGCCAGGCATGATGGCAAGTGCCT
GTAATCCCAGCTGGTTGGGAGGCTGAGGTGGGAGACTTGCTTGAACCTAGGAGGCAGAGATTGCAGTGAGCCAAGACTGT
ACCACTGCACTCCAGCCTGGGCAACAGAGCAAGTCTCTGTCTCAAAACAAAAACAAAAACACAAAGAAAAAATGTAAAAC
AATTTCATGCAGTAGCAAGCATCGAGTTAAATACAGTTGACCCTTGAACAACACAGGTTTGAATTGCACGGGTCCATTTA
TACTCACATTTCTTCCACCTCTGCCACCCCCAAAATAGCAAGACCAACCCCATCTCTTTTCCTTTCTCTTCCCCCTCCTC
AGCCTACTCAATGTGAAGATGATGAGGATGAAAACCTTTGTGATGATCCACTTCCACTTAATGAATGGTAAATATGTTTT
TTCTTACTTATGATTTTCTTAGTAGCATTTTCTTTTCTCTAGCTTCCTTTATTGTAAAAATACAGTATATAACACATATC
ACATACAAAATGTGTGTAAATGGACTGTTTGCTATTGATAAGTATTCTGGTAAACAGTAGACTATTAGTTTTTTTTGTTT
TGTGACAAGGTCTCCCTCTGTCGCCCAGCCTGGAATGCCGTGGTGTGATCATGGCTCACTGCAGCCAAAAACTTCTGGGC
TAAAGCAATCCTCTACTAAAAATACAAAAATTAGCCAGGCATGGTGGTGCGCTTCTGTAATCCCAGCTACTCAGGAGGCT
GAGGCAGGAGAATTGCTTGAACCCGGGAGGCAGAGGTTGCAGTGAGCTGAGATTGCACCGTTGCATTCCAGCCTGGACAA
CAGAGCGAGACTCCATCTCGAAAATAAAATAATAATAATAATAATAATAATAATAATAATAATAATAGGGCTGGGTGTGG
TGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGTGGACAGATCACCTGAGGTCAGGAGTCTCAATTAAAAAAT
AAATAGGCCGGGCACAGTGGCTCATGCCCATAATCCCAGCACTTTGGGAGGCCGAGGTGGGCAGATCACCTGAGGTCAGG
AGTTTGAGACCAGCCTGGCCAACACGGAGAAACGCTGCCTCTATCAAAAATACAAAAATTAGCTGGATGTGGTGGTGCAT
GCTATAATCCCAGTAATACCAGCTACTCGGAAGGCTGAGGCAGGAGAATCACTCGAATCCGGGACACGGAGGTTGCAGTG
AGCCGACATCATGCCACTGCGCTCCAGCCTGGGTGACAGTGAGACTCTGTCTCAGAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAATATATATATATATATATATATATATATATATATATATATATGTGTGTATATATATATATATACACATATAT
ATGTGTATATATATATACACACACACATATATATGTGTATATATAAAATAAAATAAATAATAATAAAACATTTACTTTGG
CTGCTGTTGCTGCGGGGAGAATTGCAGGGTGTCAAAAGTAGCACTGGTGGAGGGGTAGTGATCAAAGTCTGGTGCTTTAG
CCCAAAGGAGAAATGATAGAGACTCAGACTAGCTGGTGATGGAGGTAGAATAAGCATAAATGTATCAAAAAGAGGAGTTG
ATAGATCTTAAAGAATGATTGGATTTGAAGGGCAAAGGAAGAGAAGAATCAACCAGGTGGGTTCAGTGAATGAAACCATC
AGAAACGAATTGTCCCCTGAAATCAAGACTTTGTGATTGCCATAGTTGTATGCTTCTCAAAGGTTCCTCGTCTCCTCTTC
CTTGGACCAAAAGTCAGAGGCAAGAATGCCCTCATTCATACCCCAGTGGTCTATACCTCCAGCAGCAAGTCGAGTGAGCA
AGTGATGTCCTGAAAGGCCCAGTGGATCAGTGGAATGAAGCGGGCAGGAAGACTTAGTGCTCCTGAAACAAGGAATCCAG
AATCCAGGAGAAGGATGGCTCAGTGGGGCTTTCAAGGGACAAGTATGGGGGTTGAAGGGGTCACTGTCCCTATACCAAAT
CCGAAAATATTGTGACCAGGAACCATTCTGTCCAACTCTTCTATTTCAGGTGGCAAAGCAAAGCTATATTCAAGACCACA
TGCAAAGCTACTCCCTGAGCAAAGAGTCACAGATAAAACGGGGGCACCAGTAGAATGGCCAGGACAAACGCAGTGCAGCA
CAGAGACTCAGACCCTGGCAGCCATGCCTGCGCAGGCAGTGATGAGAGTGACATGTACTGTTGTGGACATGCACAAAAGT
GAGGTGAGTCGCAGGACAGAAGAGTGCTTTTTGTTTCAGCAGAGCAGCCTGGGGAGAGATAAAAGCTACTCCTGGGGCCT
GGGCCTGCATTCCTGAGATGTGGGTAAGAGGGGCCCAGGGTCAGAGTGTCTGGCAAGCTTGGCTCTGCCCCTTTGCTGTC
CTGGAGACTAGGGCTAATCCTGGGCTCAGGGAGTGGCCTCCCCATGGTTAGGATACAAGTGCTCATCAAGGGCCACCCCT
AGGAAGGACCAATTTTCCTATCAGAAGCTTCTAAGTTATCCTCCTTTGGCCCAAAGGGACACCTCAAGCCTACTCTGAGG
AACTCTTTCCAATGAACTAATTCCTACAGTCACTTCCCCAGCAACCTGTGCCTCAGCCTCAAGGCACTGTGGGGTAGGCC
TCAGTTTGTGGCCTGGACATCGGACTGTGGACCAGACGACTCCTCCCGATTTCTGTTTGTTTTCAGTCCTCTGACCCCAA
GCTGGCTGGTGAAGTAGGTAGAGGGAGGAGACTTTGGTGCATGCATACACACACACACACACACACACACACACACACAC
ACACACACACACACACACACGTCTCCTGTGCCCCCCAGTCTCCATGGCTGGTCAATGATTGACTGGCATTTCACAGGCCG
CTGGTTGCAGCCCCAGCCTGTTGACTTAGAGGTCACCCTCGGAAGCTAGAGCCCTGTCCTGCCTCTTCAGTGTCAGTGGT
CACTCCACTGCCCACAGGCTGGGGTCTTGGGCAAAACACACGCATCTGCCCTGATCTGAGTTTGCTGCCCTCTGTCCCGC
AGTCAGCCCCACTCTGTTCCCACTCCCTCTCCCCAGCCCCCTAGCTAGACCCCTCTCACCAGCACCCCTTTCCCTTCCCT
GAGGGTCCCCCTCGCTGTCTTTGTCCCTCAGACATCCTCTTTCCTGGGCTCTCCTGCCAGGCCCTGCTGGAGGGACAGTT
AAGGAGGAAATCGAATCAGCAGCGCCCACCCCTGCCCCCCTTCCTCTCCTCTTGTCAGACACCAGACGAGGTTTTTTCCT
CTGGCTTCCCAGCTCTGAATGGGCTCATTCTTTTTCAGAGGCTCGGCCCCTCTCGAGCCTCCTCCCCAGGGCGTGAGTTC
TGACCCCAGCTCCTCCCCCCATCCCCACTCCAGCCCCCTCTCCAGCTTGCTCCACCCTCTCTACCGCCCACCGGGACTGG
GCATTGTCTGCCAGTCCGGGTTTCTTCCTGGGATTTGGGATGCAGAGAGGATGGGTTTGCTTGGGCGGGGGGGTGGAGAG
TGAAGGGGGGAAGCAGGATCTTTGTAGAGGGAGGGACCTACAGTTACCTGGACTTCTTTCCTCTGTCTCCCCTCTTGGTA
CCCTTGACTGGGGCTCTTGAGGGTAATGGGTGAAGCCAAATCTGCCATGGCTCAGTTCCCAGCTCAGCTCTGTGACCTTG
GGAAAGTTCCTTTAGCTCGTGGAATCTCAAGGCTCAAGGTTCCTCTTCTGCAAAATGGGGAATGATAACACCTGCCTCCT
CTGGAGTCTTGGGGACTCAGTGTTCTGAGGAACGTGGCTGTAGGTCAGAGTGGCACAGAGTAGGGTCCAATGAAGCATGG
CGTCCACAGTAGCTTTCCTGACTGGACTAACCTTTCCGGACACAACAGCAGGGCAGGGGTGGGGCCTGGGGAGAAAGGAC
ACCTCTAACCCTGATCCTAACATCCCGATGGCCTCTAAGGCTGCCTGCACACTCATCCAGGTGCAAGCCCTCCAAGGTGT
GGTGTGATGAACCAGTGACTCCTGGAGCCAGGTCAGCGCATCCTCTTCCCGCAGGGCTGTAAGCTGCAGGACTGAGAGGC
AGGTTGACCAGGTCCTGGGCTGGATGATGGGGTGAGAGTAAGGGGTCAGTTTTGATACATGCCCAACTTTTCTCTCTAGC
CCTAAGACATCCTGGGCAAATTGCTTACCTCAGTTCCCCTGATCCTCACCCTAACCCTAACACCAGCTCAAGAGAAAATA
GGGATATTGATGGCCATCCAGAAGGGCTGCTGTGTTCCATACACAGCAATATTTCTCGAATGTTTGTGACAGCGGTCCAA
GGAATAAGTTAATTTTACATTATCACTCTGGATACCTGTACAAAACTCCACCTTATCCTTACTATATGAATGTGCTAGGG
TTGTTTTTTTGTTTTGTTTTTTTTTTTTTTTTTTGAGACAGAGTTTCGCTCTTGTTGCCCAGGCTGGAGTACAATGGCGC
GATCTTGGCTCACCGCAACCTCCGCTTCCCAGGTTCAAGCGATTCACCTGCCTCAGCCTTCCCGAGTAGCTGGGATTACA
GGCATGCGCCACCATGCCCGGCTAATTTTGTGTTTTTAGTAGAGACAGGGTTTCTCCATGTTGGTCAGGCTGGTACCAAA
CTCCCGACCTCAGGTGATCCACCTGCCTTGGCCTCCCAAAGTGCTGCAATTACAGGCATGAGCCACCGCACCCAGCCGTG
CTAGGGTCTTTTTCTGTTCAATTCCTTTCTCTCTCTTGCTCTCTTTCTTTCTTTCAATGGAGTCTTACTCTGTCACCCAG
GCTGGAGTGCAGTGGCAAGATCTCAGCTCACTGCAACCTCTGCCCTCTGAGTTCAAGCAATTCTCCTGCCTCAGCCTCCC
GAGTAGCTGGGATTACAGGTGCCTGCCACCACACCTAGTTAATTTTTGTACTTTTAGTAGAGATGGGGTTTTGTCATGTT
GGCCAGGCTGGTCTCGAACTCCTGACCTCGTGATCTGCCTGTCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCC
GCCATACTCGGCCAACTTTGTATTACTTTCTTAAAGAGAGTTTCCCAAATTATATAAGCTTCAGGCCCCACAAAACCTAG
ATCTGCCCCAGTATAACTAAATCTGGGACCATTTATTGAGCAATTATTATGTGCCAAGTATTGCGCTGAGTGCTTCCAGA
GCATTATCTCCTTTAACCCCAGCATAGTATGTCAGATGCTGTTTTACAGATGAGCCAACTGAGACCAGAGATGCTCAGTC
ACTTGCCCAAGGTGACATGACTGATATGGAATAGAGTCAAGATTTTTTTTTTTTTTTTTGACACGGAGTCTCACTCTGTC
TCCCAGGCTGGAGTGCAGAGGCGCAATCTCAGCTCACTGCAAGCTCTGCCTCCCAGGTTCACGCCATTCTCCTGCCTCAG
CCTCCTGAGTAGCTGGGACTACAGGCACCCGCCACCACACCTGGCTAATTTTTTGTATTTTTAGCAGAGACAGGGTTTCA
CCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCTGCCTGCCTCGGCCTCCCAAAGTGCTGGAATTACAGGT
GTGAGCCACCGCGACTGGCCAGATTCAAGATTTGAACCCAGGTCCTCTTGGTCCCAGAGGCCCCTGTTTCTCAACTCCCT
AGGATGGCATAGCAACCTGTCCCACAAGAGGTGCCTGCTTTAAGTGTGCTCAGCACATGGAAGCAAGTTTAGAAATGCAA
GTGTATACCTGTAAAGAGGTGTGGGAGATGGGGGGGAGGGAAGAGAGAAAGAGATGCTGGTGTCCTTCATTCTCCAGTCC
CTGATAGGTGCCTTTGATCCCTTCTTGACCAGTATAGCTGCATTCTTGGCTGGGGCATTCCAACTAGAACTGCCAAATTT
AGCACATAAAAATAAGGAGGCCCAGTTAAATTTGAATTTCAGATAAACAATGAATAATTTGTTAGTATAAATATGTCCCA
TGCAATATCTTGTTGAAATTAAAAAAAAAAAAAAAAGTCTTCCTTCCATCCCCACCCCTACCACTAGGCCTAAGGAATAG
GGTCAGGGGCTCCAAATAGAATGTGGTTGAGAAGTGGAATTAAGCAGGCTAATAGAAGGCAAGGGGCAAAGAAGAAACCT
TGAATGCATTGGGTGCTGGGTGCCTCCTTAAATAAGCAAGAAGGGTGCATTTTGAAGAATTGAGATAGAAGTCTTTTTGG
GCTGGGTGCAGTTGCTCGTGGTTGTAATTCCAGCACTTTGGGAGGCTGAGGCGGGAGGATCACCTGAGGTTGGGAGTTCA
AGACCAGCCTCACCAACGTGGAGAAACCCTGTCTTTACTAAAAATACAAAAAATTAGCTGGTCATGGTGGCACATGCCTG
TAATCCCAGCTGCTCGGGAGGCTGAGGCAGGAGAATCACTTGAACCAGGGAGGCAGAGGTTGTGGTGAGCAGAGATCGCG
CCATTGCTCTCCAGCCTGGGCAACAAGAGCAAAAGTTCGTTTAAAAAAAAAAAAAAGTCCTTTCGATGTGACTGTCTCCT
CCCAAATTTGTAGACCCTCTTAAGATCATGCTTTTCAGATACTTCAAAGATTCCAGAAGATATGCCCCGGGGGTCCTGGA
AGCCACAAGGTAAACACAACACATCCCCCTCCTTGACTATCAATTTTACTAGAGGATGTGGTGGGAAAACCATTATTTGA
TATTAAAACAAATAGGCTTGGGATGGAGTAGGATGCAAGCTCCCCAGGAAAGTTTAAGATAAAACCTGAGACTTAAAAGG
GTGTTAAGAGTGGCAGCCTAGGGAATTTATCCCGGACTCCGGGGGAGGGGGCAGAGTCACCAGCCTCTGCATTTAGGGAT
TCTCCGAGGAAAAGTGTGAGAACGGCTGCAGGCAACCCAGGCGTCCCGGCGCTAGGAGGGACGCACCCAGGCCTGCGCGA
AGAGAGGGAGAAAGTGAAGCTGGGAGTTGCCACTCCCAGACTTGTTGGAATGCAGTTGGAGGGGGCGAGCTGGGAGCGCG
CTTGCTCCCAATCACAGGAGAAGGAGGAGGTGGAGGAGGAGGGCTGCTTGAGGAAGTATAAGAATGAAGTTGTGAAGCTG
AGATTCCCCTCCATTGGGACCGGAGAAACCAGGGGAGCCCCCCGGGCAGCCGCGCGCCCCTTCCCACGGGGCCCTTTACT
GCGCCGCGCGCCCGGCCCCCACCCCTCGCAGCACCCCGCGCCCCGCGCCCTCCCAGCCGGGTCCAGCCGGAGCCATGGGG
CCGGAGCCGCAGTGAGCACCATGGAGCTGGCGGCCTTGTGCCGCTGGGGGCTCCTCCTCGCCCTCTTGCCCCCCGGAGCC
GCGAGCACCCAAGGTGGGTCTGGTGTGGGGAGGGGACGGAGCAGCGGCGGGACCCTGCCCTGTGGATGCCCCGCCGAGGT
CCCGCGGCCGGCGGGGCCAGAGGGGCCCGGACGAGCTCTCCTATCCCGAAGTTGTGGACAGTCGAGACGCTCAGGGCAGC
CGGGCCCTGGGGCCCTCGGGCGGGAGGGGGCAGTTACACGGCAGCGGCTCGAGATGGCCCATCCAAGAGACTGGCGCTTT
CCAGGCTCCGAGGGGCTCCGGGAACTTGTCAAAGAAGTTCTCTGAAATTGTTCAGAAAGTTTTCCCGCAAAGGGTGTATT
GCGTAGAGCGCGCGCGCGCGTTTCCCCCCTTCTTGAGCCCCCTCAAGCTTTCTCAAAGCCTTTCCAGTTGGCAGCCTCCG
CCTCCGGACTGGCCTGGGCTGGATTCCTTGGGGGGGTCCTCTGCCCTGCCCCTCCTCCAGCCCCTCCCCGCTCCCCTTCA
GACGATTTTGGTTTGGTTGCTCCTGCTTCTGGCGGGGTCGGGTGTGTGTGTGTGTGGTGGAGTGGAGGGTGGCATAGCAA
CCTGTCCCAACCAGAGCCGGGGAGGAAAGGGTGGCCCGGAGGGTGGCCTCTTGCTGGGGTCTGGGTTGGGGGCGGGGGAG
ACGTTTGCTTTGAACAGATTCTTGGGGCCAGCTTAGGGACTGTGCTCTGTGACTTTTGGAGCGCGTGGACCATGGAGGGG
TGGGGGTGGGTTTCTTGGGGTGTAAAGTGGGAGAGTTCCCAGAGAAGGAAGCTAAGAAATAAGGCCAGATGGGAGCCTAG
GGAGGGCTGCGTTGTTCTGCTGCCTTTTCCTTGGTGCTGTGCGTGGGGAAGGGTGAGTGGGGGCAGTGTGTATCCTGACC
CATCTGTCCACCTGTGTGCATTAATCATAAAAGCTAACATATAGCCTGGGCCAGGTATACTCTGCCAGGAACTGTTTGTG
GTGTTTTGCATGCATTCTCCTTTAATCCTAGAACACCCCTATAGTGGAAGTTCTGCCAGCATTCTGGACTGAGTAGCAGT
CCAGAGGTTGAGTAGCAGCTAGTAAGTGGTGGGGTCAAGATGGGACCCCAGGCAGTGCGACCCCCAACCATGCATTCGAA
ATCGCTATATGGATGAGTGCACCTGGAGCAATGAGGGACACTGCTCCCTGAGTCACTGGGCTGCAGGGGAGACAAAATGA
AAGTGTTCTGGGAGTCGTGGGTGGTCTCCATAGGTCAGAGGGTCTGGGGAGGGAGTGGGTGTCATCGTGGCTGTGTGTTG
CCCGAGGGGCCCTCTGTGAGTGAGTGCATGGCCGTGTTATCTCTGCAGGTCTACGCCAGGGTGTTCCTCAGTTGTGTGGT
CTTTGTATTTGTGTGTCTGGGCTTTGTGTTGCCAAACAGCAGTCTCTCTGCTGACTTGGGGACACAGGCTGAACTCTGTC
CTCTGCAGGAACTCCCTTAAGGTGCTGGGCCAGATCTGCCATAAACAGAGGGAGGTAGCCTTCTATGGCCACGCCTTCTT
GCTGAGGAAGAAGGTTCCTCTCTTCCAGGGAGTACATCCTTGCCCTCCCTGTTTCCCAGACAAGCATCTTCACCTCTCAT
CTTCTGATGAGAAGGGTGAGGCCATACTGAGCTGTCAGGCTGAGCTGCTGCCCTTCCTCACCTTGGGCTGGGAGTTGATC
AGGGAATGGCAGTTGCTGCAGAGCTGGATTTGAGGGCTGGGTTCTCTGGATGGGGCCTCCTCATGTCCTCACCCCTCAAC
CTGCACTATTGATTGTGTTGTGCAGGAGTTAGTTAAAAAGTCATTGCACAGCCTGGGCAACAAGGCAAAACTCTGTACAA
AAAATACAAAAATTAGTTGGATGTGATTACACGTGCCTGTAGTCCCAGCTACTCCGGAGGCTGAGGCAGGAGGATCACCT
GAGCCCAGGAAGTTGAGGCTTGCAGTGAGCTGTGATTGCAAATGCTCTCCAGCCTGGGTGACAGTGTGAGACTCCGTTTC
AGAAAAAAAGTATACCACCCAGCTGCCTCCAGCACCCAGATTTTACCCAAGGGGTGAGGTCTGGGGCAGGAATGTGGGGG
AAGGGGAGGCCTAGGGGGAGCCCCAGAGGGGTCAGGATTTTTCTGAAATCCTTTCTTAGAGGTATGGGTTTTACAAATTG
CAGCAAATACATCCTTTTAATCTTGCAGAACTCCTTCATATTTTAATTCCAGTATGATTCTTCCAACAGCCTCCTCTCTT
TACTATACTTGGGGAAAGTACTCATTTTATTTGTCAAGAAAAAAACAATTGAAAAGATAGGGATCAAATGTAAAAAGAAA
AAATACGTGGCATTCCAAAGTCAAACACAAAGCATGTTTAATTTTCTCGTGGTTTGGGATTACCCATATTCCTGCTGTAT
GAACCTGTCTTGTCTTAACTTTTAAGAAATGTACGGTGTACTTCCTATATGCTAGGTTTTTATCCATGCTTTCATTTAAT
CTCTGTGACAGTCCTGTGAAGTAGGTGCACAGATGAGAAAATGGAAGTTCAGAGAAATGAAGCAACTTATCCAAGGCTCC
CAGCTACCCAGTAATGTCCAGGGAATTTTTGGACTCTGAAGAGGAGGCATTAAGAGGTGGTTAGAGTCTTATTCCAGCCA
ACAATAATGGGTTGAACAAAGCCTTAGGGGCAGGCAGGTGGCCAGATGGGAGGAGAAGCGCTCCTCTTGTTCAGGCGAAT
GACCTTTCCATCCACTTCTCTAGGCTGTAGAAAGTGGAGCTGAGCTGGGGGCCCTGAGGTTCCCTCTTGACTTCAGAGTC
CTCTCCCTTCCTGTCCAGCCAATGCCTGTCTTCCTTTTGGGCCCTACCAGCATGACAGGGGGCTGCGGGCAGGAGGGGAC
AGAGGCCACGTTGACACACAGGGCTGTGGGTGAGAGAGACAGCTGAAGTGTCAGCGTGAGGGGCCAGTGTGGGGCTGCGG
CTGGGAGGGCTGGGGTGGGGCCCAGGGTAGTTGTGCCTGTCCTTGGGTGATGGAATGATCTGGAAAGAGATTCCTTCCCT
GCCCTCCACCTGTGAGAAGCCCCTCTAGAGTGACATCTCCATCTTATGTTTGGCCACCCATCCTCCCCCTGGGAAGAGAG
CCGAGGTGGGGTAAGGGATGTGTACTCTTTCAAGGAGTGGGAGAATTATTCTAGCGAATGTTTGTGTTGTCCCAGTTCTG
TTTACAAAGCCTCGTCATGTTTACAGATGGCTGCGCAATTCATTACCTCATTTAACTCTCATGTACCTCCTCTGAGGGAG
TAAGAGCTGTTACAGCCAAGTTTAGGTCAGTAAATATTCACCAAGTTGCAGGTACTGCAGGGCATAGAGATGAATCCGAT
TTAGCTTCTGCCCTGGAGGTCTGGGAACTTGCTCAAGATCACTCAGTGAGCAGCTGAGCTAGGGTTCTCAACTAAAGACC
CTGGGCCCAGGCCCTGGTCTGATGTCAGGCCTGATACACCAGGTGTTTGTGGTCGGGGAATCCCAGTGTCACTTGAATGG
GCTGTGACATTATGGGTCTGGGAGAGCTGAGCTTTGGGGACACAGGTCATTTTACTGTAGTATTCATGGAAACCAAGGGA
AGTATTGGCTTTTCTGCTGTGAGCAAGAGGAGCAGCTGGGGCTGCAAGCTGGTGGGGAGGAGAGAACCCACCTGAGAGAA
ACCTCAGGACTGGGGTCAAGTCCTGACCACCAGAGTCCAGAGAGACATGAAGGACTGTGACCAGCTCTGAGCAGAGAGAT
GGATTCCATGACCTCAACTGGTCCCTTTTGTTCGGAGACTCGTGACTGGACTTCATTCATCCACTCATTCATTCATTCAC
TCAGCAGACACTTATCTAGCGCTCCCTGTGGCTGGTCCTGCCTCATACTGTCTTTGCTCTGGAGAATTGGAGGTTGGGGT
TCCTGAGGGGCAGGGTCCTGGAGACAAGGACACTCCTGGGTAGAATTAGGACCTACCCCCCAGGAAATCAACGGGGACCA
GGTGCCGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGACGGGCGGATCACAAGGTCAGCAGTTCAGGACCA
GCCTGGCCAACATGGTGAAACCCGCCTCAACTAAAAATACAAAAATTAGCCAGGTGTGGTGTCAGGCACCCGTAATCCCA
GCTACTGAGGAGGCTGAGGCAGGAGAATTGCTTGAACCCGGGAGGCAGAGGTTGCAGTGAGCCGAGATTGCGCCACTGCA
CTCCAGCCTGGCGACAGGGCGAGACTCCATCTCAAAAAAAGAAAACCAATGGGACAGGGCAGATATGGGGACAATGGTAA
GGAGATGGGAGAGTGGGAGGGAGGTGTCAGGAAGACCTTCTTGACTTCATGTAGGCTGGTGGGGGTGTTAGCCAGCAAGC
CTCCAGTTCCCTGGGAACCGTTCTCAGGGTACCAATTTTACCACCTGTCTGCAAACACTTTAAGATTCTTAATCAGACTC
AAATTGGCCACAAATCAGGTAAACAAACTCACTAGTGGGGTGGGGCTACCACCCGTTCTGACCCTCCAGCCCAACCCAGC
CCAGCCACCCTGCCCTCCGTAGAGCCTGTGGTGTTTATCGGTGGCATTGGGAGAATTAGTGTGTATTTATGTTGGCGTGG
GGTGTGGGGTGGATTTGTGTGTGTGCAGTTAGGCCTAGTGGAAGGAATGTGGGATCTGAAGGCAGGCCAGCCTGAGTTCC
AGTCCTGCCTGTTGCTCACAAGCTTTATGAGGCGAGAGCTAACCCCTGCCAGCCTCAGTTGTCTTCTTTGCAAGATGGAG
GTTGCAGCCCCAGTCTCTGGAGCATGTTATGCAGATCCACCGAGAGTGCCTGCCAGGCACACAGTAGGTGCTCAGCTCAG
TTACTGTGGCGGCCCCCACTCCCCATTGTTGTTGTTTTCCTATTGCCTGGCGGCCACAGCTGGTATCCCTTGAAAAGGGC
TACAGGGGGTGGAGTCGGACCCTGCCCCAGCCCTGTGGAGACCCTGGGCTTGGGCCAGGGCCTGGGGTCTGGGCCTGCAG
ACAGCTGTGTCTATAAAGCAGCTGAAGGGCTGAGGCCGGGGGAGGTCCTGGCAGCAGGGCGTTATTTTGGGCCTGGCCTG
CCACCCCCAGCTCCTGTTTCTCTTGGGAGTCTGTTGGGGGAGGAAGTGTGGGGAAGAGGAGGGGGTGCAAGTGGGTGAGG
CATGGAGTGGGGAGGCCTCCCTCAGGGACATGGACCCTTGAGTTCTATTTCTGTTCCTCCCTCCTGTTCCTCCCTCTTTG
TCCTTATCTGCCTAGAGAGGTGGGAATAGAGGCCATTCTGAGTATCACTAGGAGACCACCAGTTTGTGGCCACTGGCCAC
TGGCCCAGGCAGGGAACCTGGGGGCTTGCCCTACCAGCCTCTCCCAGCAATCTGAAGGCAGGGGGTACCTCGTATTACCC
CCTAGGATTTGACCTTAGGCTCCAACTTGCTGGGAGAGCAGTGCCTCTGGTGTCAGACCCCAAGCCAGCCCTTGTGCTGT
CCCTGAATCTGCATGTAGCCTGTGGGAGGCGGAGCAGTGACCGGCAGGAATTCTGGGCAGCTCAGGCACCTGTGGGCCTG
AGGGTGCCCTCTGCCCCCACCCTTCCGATCTCCTGGGCAAGACACGCCAGGTGATTCATCTCACCAGAGCAGAAAAACAA
GTTCAACTGGGCACTTTAATCTCCCCTCACTGGCAGGCCTGGTGTGAGCTGCTACCCCGGCGCCCCTCACCAGGGGTGCT
TTACCTCCTCTAGTATTCCTGACCTTAGTGGGCATTTCTGGTCTCAGGGATACCAGGCTGGGGTCCAAGTGGGCCAGGTG
TGGCAGTTCAGCCCTATGCCCCATGGCTGATGGCTCGCGCTGGGCAGGTATGCAGGGCTGACGTAGTGCCTTTGTGGCAG
CAGTTTCGTGGCACACATTCTGCCAGCTGGTTCTGGAGTCTTGCCCTGAGGAGGTGGCCAGGGTGAGGGTGCCAGCGCAG
GAACCTTTGGCGCATGCTTCACCCTGGCCTGGGATCTGCAGCCTGGGTCCAGATGCCCACAACTGGAATCTGACGCTCCT
TTTCTCTTCATGGGGGACTCCCAGAGGTCTCTGCAATGACCAGAGCCCCGGTTGTCCCATGCCTCAGCTGCAACTCCAGC
TGACCCTCCTTCCCCACTCTCTGGGTGGCATTACGGGGGTGTGGATCCCTTGCCAAGAGGTTGGCATGTGGGTGTGCTGG
AATGGCATAGGGAGAATGCACCGAGTTTGTTTGCTTGGGAGAGGGGCAGGGGGTATCCAGAAGATTCATGATTCGTCATC
GCCTCTCTTGGGGGATTTTTACCCCTTTGCCCTGAGTTGTGCCTTTGGGACAAAGGAAGCCTTTCTTTGCCAGCCAACAC
CCTGTACTGGCGGGCGAGCTCCCCAGGGCTGGCACGCTGGGGCAGCCTCTGAATGCACAGGGTGGGCCTAGTCAGAAGAA
GCCTTTCCCCTGAAATCCCTCTACTTCCCAAGCACGCAAGCTTTCTCCTGCTGTTAAACCTGCAGTGTGCAAGGGACATG
GGCGGAGGGGTCCTTCAGTCAGGCTTCTCCCTGTCTGAGGTGGCATGACTTGGAGTGAGTTTGGATGGGGTGGCCAGGTC
TGAGAAGGTCCCCCGCCAGTGTCCTCTGACCCATCTGCTCTCTCCTGCCAGTGTGCACCGGCACAGACATGAAGCTGCGG
CTCCCTGCCAGTCCCGAGACCCACCTGGACATGCTCCGCCACCTCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCTGGA
ACTCACCTACCTGCCCACCAATGCCAGCCTGTCCTTCCTGCAGGTGAGGCCCGTGGGCAACCCAGCCAGGCCCTGCCTCC
AGCTGGGCTGAGCCCTCTGTTTACAGGTGGGTGGCAGAAGAAGGTGCCCTGCCCTTCTGTTTCCTCTCTTGTTGTGGTTT
CTCAACCAGGAAGTCCTTTCTAACATCTAACCCCCATTCATTTTACTGCAGAATCAGTTGACTCTCTCTATAACGTGGCT
GGCCGAGGTCATGTCTGGATGGGATGCGTCTGTGTTTCCGCTAAATCTTGTGCTCTCTTGCCAGCATGATCATGTCCCCT
GTCCACCTGCTCCAGCCACTATCCCTCTCCCACTTACAGCAGAAGAAAGGGCTGGTGAGAAAGGTGGATTACAGGCCCAC
TTCTGCCACTGACGAGCCCTATGAATGTGGCCTACACCCCCTTAGCTTCACTGGGTCTCAGTTTCCCTATCTGTATATTG
GGAGCAGTTGTGAAGCTCAGAAGAGAAATGTCTGTGAAAAGGTTATGAACAGGAGGGAGAGTGGAAACCAACCTGCTGGA
TCGTGTCCACAGACCCTGGAATGGGGCCACATGCTTGGTTTGTCAAATTGCAGACGCCGGCCGGGTGCGATGGCTCATGC
CTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGACAGATCACTTGAGGTCGGGAGTTCGAGACCAGCCTGACCAACATGG
AGAAACCCCGTCTCTACTGAAAATACAAAATTAGCCAGGCATGGTGGCACATGCCTATAATCCCAGCTACTTGGGAAGGC
TGAGGCAGGAGAATCACTTGAACCTGGGAGACGGAGGTTGTGGTGAGCCTAGATCGTGCCATTGTACTCCAGCCTGGGCA
ACAAGAGTGAAACTCCGTCTCAAAAAAAAAAAATTTGCAGACGCCATCCCATCCAGGCCTTTGCTTTCACTGATGAAGAA
ACTGAGATACAGAGAGGGCAGGGCACCTGTTCGGAGTTTATGAAATGCCCCCCCACCATTATCTTTCTTGATCATATAAG
AATCTGGTGAGGCAAGGTAGGGCGTGATCTTTATCTCTATTTTATCGTTTTATTTAAGCGGGAACAGGACTGCTCAGTGG
CTGGGGGCCTTGCCCAAGATCTCCAAGTACTGGGGAACCCCAGGGAGGCCCTGGGGGGTGGCAGTGTTCCTATTTCAGCC
CCACTCTGCTTCCCCCTCCCAGGATATCCAGGAGGTGCAGGGCTACGTGCTCATCGCTCACAACCAAGTGAGGCAGGTCC
CACTGCAGAGGCTGCGGATTGTGCGAGGCACCCAGCTCTTTGAGGACAACTATGCCCTGGCCGTGCTAGACAATGGAGAC
CCGCTGAACAATACCACCCCTGTCACAGGGGCCTCCCCAGGAGGCCTGCGGGAGCTGCAGCTTCGAAGCCTCACAGGTGG
CCTTCACCGTCATTGAAACCTTCTCTTGGTTATTCAGAGCTGACCAGGGCCACTGCTAACCAGGGGGAGGCTTTGTGTGC
ATTAGAAATGGTGTCCCTTCTGGGCAGACGCAGGCAGAGCCCGGGAAGACGCCCTCAGAAGATTGGAAAAAGATTCCCCT
TCTTCCTGGGAAGTTGTAGCTTGCGTCAGCACATATAATTCAATCGTGAGAATGCAGGCTGGGTTTTTGCCCCCACTTGG
CTGAGTGAAGTGTACAGTGAACAACCTATGTAACTATTTGCTGGCCCTGGAGCCGACTCTGCCCCAGAGTCTGGGTGCCA
GGTGCTTTGCCCGCATGGCCCATTTCAGTCACGCTGCAGTCCTGTCAGGAAAAAATCAGTGTTATTCTCATTCTACATAT
GAGAAAACTGAGGCTTGCAGATATAAGGGCCAAAAGTTACACAGCTAGTGAGTGATGGGGCTGAGTTTCAGACTCCACAG
TCTCTTAACCACCAAGCAGCATGCCCAGAGTAGAGGTGAGAAGGAAGGAGAGAGCTGCGGTCCACATGAGCATCTGGACC
TAGCATGGACAACTCACTCCTCCCTGGCTCTCGCTTTGTTCTTGTTGCGGGTGTGGTGGTGGTGGGACTCAAAGACGGTA
AAGATAGCTTTCTCTCCTCCCTGGGGAATCTGGGGGTTGTTTAAAAGGCCTGCTCCTCTTTTAGAAGGCAGGAGGGCCCC
AAGGGAAGCAGAAGGTGACAGAAGGGGAAAGGGTCCTCTGATCATTGCTCACCCCACAGAGATCTTGAAAGGAGGGGTCT
TGATCCAGCGGAACCCCCAGCTCTGCTACCAGGACACGATTTTGTGGAAGGACATCTTCCACAAGAACAACCAGCTGGCT
CTCACACTGATAGACACCAACCGCTCTCGGGCCTGTAAGCCATGCCCCTCCCTGCTGCCTCTTCTCTCAGACAGCCTGAC
CCCAGCCGCAAACTCCCAACTTACAACCCAGTGCCTGCCCGCCACTGCCCCAGCCGCCTACACCACCCATTTCCTCCCTC
TCTGTCCCTCCTGCCATCTCCCTGTGCCTCTTCATCTCTGGGGTTCTCTGTCTTGTCTCCCTCTGCTTATAGGTTGTGCC
TCTGGTTTGGGGGCCTCTCAGCCTGTCTGGGTCCCTCCCTTGCTGTGCAGTTGGCCTCGTGGCCTCTGCTGCTGTTTGTG
CCTCTCTCTGTTACTAACCCGTCCTCTCGCTGTTAGACATCTCTCTCACTGCCTGTCTCTGGTTCTGTCCTCAGGCCACC
CCTGTTCTCCGATGTGTAAGGGCTCCCGCTGCTGGGGAGAGAGTTCTGAGGATTGTCAGAGCCGTGAGTCTCAGGGAGGC
CTGGAGTCAGGGAAGGGGAGGGCTGGGGCCGGGTGGAATGCAGGTGTCATACAGGTGACATGGGAGGGGTGGGATAACAG
GCTTGGGATGTCTCCCCTGGGCCAGGTAGTCTCCCTAGAAGGTGATGCTGATGAGGGTCTGGTGCCCAGGGCGCCACTCA
GCCCTCATCCTGCCCTTTGCCCAACAGTGACGCGCACTGTCTGTGCCGGTGGCTGTGCCCGCTGCAAGGGGCCACTGCCC
ACTGACTGCTGCCATGAGCAGTGTGCTGCCGGCTGCACGGGCCCCAAGCACTCTGACTGCCTGGTATGTGCCTCTGCTTT
GTGCCCAATGTGCTCTACCCCCCAGGATGCAAGGGGTGGGCACCCTGCCTGGTACTGCCCTATTGCCCCTGGCACACCAG
GGCAAAACAGCACAGTGAAAGCCAGCCACCTGTCCCCCCAGGCCTGCCTCCACTTCAACCACAGTGGCATCTGTGAGCTG
CACTGCCCAGCCCTGGTCACCTACAACACAGACACGTTTGAGTCCATGCCCAATCCCGAGGGCCGGTATACATTCGGCGC
CAGCTGTGTGACTGCCTGTCCCTGTGAGTGCCAGGGAGAAACACAGTTTTCTCATTTTGGTGGGGAGGTTTGTTTCTGTA
AATGGGAGCATATGGGGAGCACTGTCTGCATCTTGCTTTGAGAGCTGGTCATGACAGTTCCTGCCGAGCTGCCTTGTTCT
TTCAACAGCTGTGGAGCAGGTGGCAGTAAGGAGAGGCAGCTAAGAGCCCAGACTTGGGAGCCAGACTGCCTGGGTTTGAA
ACCCAGCTCTATCAATTAGTAGGCACGTGACCCTCTTGCTGTGCCTCAGTTTCCTCATCAGTAAAATGGGGGCAAGAATA
GTCCCAACTGCATAAGATGGTTATAACATTTGAAAGAGTTAATATTTGTAAAGCTCTTAGAACGGTGCCTGGTATGTACT
AAGTGCTCCTAAATGTTAGCTTTTATTCTATAGCCTGGTGAGGTCAGTTTTACCTTTCGTTTTGTTTTTGAGACCGAATT
TAGTTAGCTCTATCGCAGTGGCGCGATCTCGGCTCACTGCAACCTCCGCCTCCCAGGTTCGTGCTATTCTCGTGTCTCAG
CCTCCTGAGTAGCTGGGATTACAGGCGCCCACCACCATGCCTCGCTAAATTTTGTATTTTTAGTAGAGACAGGGTTTCAC
CACGTTGGCCAGACTGGTCTCGAACTCCTGACTTCAGGCGATCCACCTGCCTCGGCCTCTGAAAGTGCTGGGATTACAGG
CGTGAGCCACTGCACCCGGACTTTTTTTTTTTTGGCAGAGTCTCGCTCCATTGCCCAGGCTGGAGTGCAGTGGTGCAATT
TTGGCTCACTGCAACCTCTGCCTTCCGCATTCAAGCAATTCTTGTGCCTCAGACTCTTGAGTAGGTGGAACTACAGGCAT
GCACCACCATGGCTGGGTAATTTTTGTATTTTTAGTAGAGACGGAGTTTCACTATGTTGGCCAAGCTGGTCTCGAACTCC
TGACCTCAAGTGATCCACCCGCCTTGGTCTCCCAAAGTGCTGGGATTACAGGCATGAGCCATCGTGCCTGGCCTAGCTCA
GTTTTATTTAACAGATCACCTATTTACTGATGGGCGTTTATGGACTGGGCTCAGACCTGGGGAACCTCTTTCCTCCTCTC
ACAGGAACAGGAGTGGGCCTTCAGATCCTGGCTGACTGTGTTAGGGAGAGGACAAAATGTAGAGCCAGACCATTTGGGTT
CAAATCCTCGCTCCTCCACTCACTAGCACAATGACCTTGAATAATTTACAGAACTCTCTGCTTTGGTCTCCCTTTTTGCA
AAATGGGAATCTCACAGTGCTGATCCCGTCTGGTTGTTGTGAGGGGTAAATGGATGTCAGGTGCTGATGCGTGGTAGGGC
ATTTAAGTATTGGTTGATATTATTCTTCTTGTGCCTGGGCACGGTAATGCTGCTCATGGTGGTGCACGAAGGGCCAGGGT
ATGTGGCTACATGTTCCTGATCTCCTTAGACAACTACCTTTCTACGGACGTGGGATCCTGCACCCTCGTCTGCCCCCTGC
ACAACCAAGAGGTGACAGCAGAGGATGGAACACAGCGGTGTGAGAAGTGCAGCAAGCCCTGTGCCCGAGGTACCCACTCA
CTGCCCCCGAGGCCAGCTGCAGTTCCTGTCCCTCTGCGCATGCAGCCTGGCCCAGCCCACCCTGTCCTATCCTTCCTCAG
ACCCTCTTGGGACCTAGTCTCTGCCTTCTACTCTCTACCCCTGGCCCCCCTCAGCCCTACAAGTGTCCCTATATCCCCTG
TCAGTGTGGGGAGGGGCCCGGACCCTGATGCTCATGTGGCTGTTGACCTGTCCCGGTATGAAGGCTGAGACGGCCCCTTC
CCCACCCACCCCCACCTCCTCAGTGTGCTATGGTCTGGGCATGGAGCACTTGCGAGAGGTGAGGGCAGTTACCAGTGCCA
ATATCCAGGAGTTTGCTGGCTGCAAGAAGATCTTTGGGAGCCTGGCATTTCTGCCGGAGAGCTTTGATGGGTAAGAGTGG
GCACGATGACCTGAGACAGTGTCAGGGCAGACAGAGTCCTGAGGATCCAGATGTGGCAGCATCTCTTGGGGATGGCAGGA
GACAGAAGTGGGGGGATCAAGAATGCAAAGAAAGCAGATGGGAGACCAGAGGAGCAGGGCCTTTGGTGGGTGGGGGTGAT
TATTTTTGTAAATGACATGCTATCCGTGAACAAGGACTTGTATGGAGGTCAGACCATCTAGATAAAGTAAAATTCCCTTT
GAGTTCATAGCAGCTTTATTCAAAATATCCCCAAATTGGAAATAACTCAAATGTGCATCACTAGGTGAAGGAATAAACAA
GTGGCAGTGTATCCATTTGGTGAAGTTCTACTTAGCAACCAAAGGAAATGAACTACCGATACAACATAAATGAATCTCAG
AAACATTACATTGAGCAAAAGAAGCCAGAGACAAGATTCCATACTGTCTGATCCCCTTTATGTGAGGCTCTGAACCGAAA
AAACCACTCTGTGGTGGGAGAGATCAGAACGGTGGTTGCCCCAGGGTGGGGGGCTTCAAAAGGGAGGCACACAAGGACAT
TTCTGGGGTAATAGAAATGCTCTGTATAGTGATTGGGGTAGTGGATACATGAGCGAATCCATTTGTCAAAACTCATCAAA
CTGTGTGATAAGAGTCTGTGCATTTTATTTATTTCATTTTATTTTTTGAGATAGAGTCTCACTCTGTCAGCAGGCTGGAG
TGCAGTGGTACGATCTTGGCTCACTGCAACCTCTGCCTCCTGGATTCAAGCAATTCTCCTGCCTCAGTCTCCTGAGTAGC
TGGGACTACAGGTGTGTGCCACCATGCCCAGCTAATTTTTGTATTTTTAATAGAGATGGGGTTTCACCATGTTGGCAAGG
ATGGTCTCGATCTCTTGACGTCGTGATCCGCCCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCACAC
CCGGTGCATTTTATTGTATATAAGTTATACTTCAATAAGAAATGAATTGGGGCCAGGCACGGTGGCTCACGCCTGTAATC
CCAGCACTTTGGGAGGCCGAGGCAGGCAGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCC
CATCTCTACTAAAAAATATAAAAAATTAGCCAGGCTTCCTGGCATGCGCCTATCATCCCAGCTACTTGGGAGGCTGAGGC
AGGAGAATTGCATGAACTCGGGAGGTGGAGGTTGTAGTGAGCTGAGATTTCGCTATTGCACTCCAGCCTGGGCGACAGAG
TGAGACCCTGTCTCAAAAAGAAAAAAAAAAAAAAGGGTCAGGCGCCGTGGTGCACACCTGTAATCCCAGCACTTTGGGAG
GCTGAAGCAGGAAGATTGCTTGAGCCCAGGAATTCAAGAACAGCGTGGGCAACATAGTGAGATCCCATCTCTACAAAAAA
ACACAAAAAATTAGCCGGGCATGGTGGTACGCACCTGTAGTCTCAGCTACTAGGGAGACTGAGGTGGGAGAATCACCTGA
GCCTGGGAGGTGGAGGTTGCAGTGGGTTGAAATCATGTCACTGTACTCCAGCCTGGGTGACAGAATGAGACCCTGTCTCA
AAAAAAAAAAAAAAAAAAAAATTCCCTTTCACACTTCCTTTACCTCCACTCCCCTTTCCAGAGGGGGCCATGGTTAACAG
TGTGTGTGTTCACCTAGACCGTTTATGCATCTGTAGACACACACACAGTGAAGTGTGGTTTTCGTCGTTTTGGTGGGGAG
GTTGGTTTCTGTAAATGGGAACATATAGGGAGCACTGTCTGCACCTTGCTTTGAGAGCCGGTCATGACAGTTCCCATTGA
ACTGCCTTGTTCTTTCAATAGCTGCAGAGCAGGTGGCGGCAAGGAGAGGCAGCTAAGAGCCCAGACTTGGGAGCCAGACT
GCCTGGGTTTGAAACCCGGCTCTACCACTTACTAGGCATGTGACCCTTGTGCTGTGCCTCAGTTTCTTCATCTGTAAAGT
GGGGGCAAGAACAGTCCCAACTTCATAAGATGGTTATACCACCATGCCTGGCCAGATGATTATAAAGTTTGAATGAGTTA
ATATTTGTAAAGCTCTTAGAACAGTGCCTGGCAGATACTAGGTGCTCCTAAATGTTGGTTTTTATTATGTGGCTGGGTGG
CTCGGGGTTTTATTTAACAGCTCCCCTATTTACTAATAGACATTTAGATCATGTTCCATTTTCACTCTTACAAACAGTTC
CACTTTGTGTGTGGCTCTGGGAACATGGGCCAGTGTCTCCCTAGGCCACATTCCTAGAAATAAGATTTCTTTTCTTTTTT
TTTTTTTTTTGAGACAGAGTCTCGCTTTATCGCCAGGCTGGTGTGCAGTAGTGTGATCTCGGCTCACTGCAACCTCTGCC
TCCCGGGTTCAAGTGATTCTCCTGCCTCAGCCTCTCGAGTAACTGGGACTATAGGCGCGCGGCACCACACCCAGCTAATT
TTTGTATTTGTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGATGGTCTCCATCTCTTGACTTCGTGATCCGCCCGCCT
CGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTGAGCCCAGGCAGAAATAAGATTTCTAGATCAAAGGATATAA
ATACTGTTTTGATAGATGTTGCCGAACTAAGGCCTGGGCTTTGAAGCCCAGGATGGGAACAGCTGGGCTCGATGGGCAAA
GGGTTTGAGTGAAGGCATTCATGGTGGGGAGTGGCTGGCATGGCCAGTGCTGGGAGTGATGTCCACCCTGTTCCTGGCCC
TGCTGACTCCTCTCCTGACCCCTCCAGGGACCCAGCCTCCAACACTGCCCCGCTCCAGCCAGAGCAGCTCCAAGTGTTTG
AGACTCTGGAAGAGATCACAGGTGGGCTCTGTCTCTGCATCCTGTTCTGCAGGGGCTGGGAGTCCTTGTCCTGTCCCCAC
TCCTTTAATCTCACCCTCTGCCTGCAGGTTACCTATACATCTCAGCATGGCCGGACAGCCTGCCTGACCTCAGCGTCTTC
CAGAACCTGCAAGTAATCCGGGGACGAATTCTGCACAAGTGAGCACTGAGAAAGAGGGGGCCTGATGGGGAGGAGTCCCA
GGGAGGAGTCCCTGTGGGAAGCTTTGGGCCTGAGGGAGTACTCCTGTAGCAGTAACCTTTCCATGAAAGTCTGCAGAGTG
TGCTGGGGATGGAGGAAGATGAGAATAGCCTTTGCTGACCGGGAAGGGGTCCGTGGTAAGGTGCCCACCTTTCTCCCATA
GTGGCGCCTACTCGCTGACCCTGCAAGGGCTGGGCATCAGCTGGCTGGGGCTGCGCTCACTGAGGGAACTGGGCAGTGGA
CTGGCCCTCATCCACCATAACACCCACCTCTGCTTCGTGCACACGGTGCCCTGGGACCAGCTCTTTCGGAACCCGCACCA
AGCTCTGCTCCACACTGCCAACCGGCCAGAGGACGAGTGTGGTAAGACAGGGAGCCCAGTGTGCGCACTCCCCATCTGCC
AGCACACAGCAGTGCCCAGGGGGCCCTGGCAGCAGCGTTCTTGGACTTGTGCAGACTGCCCGTCTCTGTGCACCCTTCTT
GACTCAGCACAGCTCTGGCTGGCTTGGCCTCTTGGCATGGCTTCTCTAGCTGGGTCCTACCTGCCTTGGCATCCTTCCCT
CCCCCTCTGTTTCTGAAATCTCAGAACTCTTCCTCTCCCTACATCGGCCCCACCTGTCCCCACCCCTCCAGCCCACAGCC
ATGCCCACAGCCAGTTCCCTGGTTCACTTGGACCTGGGGCCTCCCCTAAAAGTCCCCTGCGGTCCCTTCCTCCTCACTGC
AGTGGGCGAGGGCCTGGCCTGCCACCAGCTGTGCGCCCGAGGGCACTGCTGGGGTCCAGGGCCCACCCAGTGTGTCAACT
GCAGCCAGTTCCTTCGGGGCCAGGAGTGCGTGGAGGAATGCCGAGTACTGCAGGGGTATGAGGGGCGGAGGAGAGGGTGG
CTGGAGGGGTGCATGGGGCTCCTCTCAGACCCCCTCACCACTGTCCCTTCTCTCAGGCTCCCCAGGGAGTATGTGAATGC
CAGGCACTGTTTGCCGTGCCACCCTGAGTGTCAGCCCCAGAATGGCTCAGTGACCTGTTTTGGACCGGTGAGCTGCTGGC
GGGCTCAGAGCTGGGTGGAGGGGGGCAGCGAGGGGGATTGCCAGGGACTTGGCAGGATGGCGAGATGCAGTAGGGTGTGC
TATCTGGTAAAATATCCCTGGAGAGGGCTCAGCGCTCAGACCTGAACAGCAACAGAGTGGCAGAAAAGGGGCCTGGGGGA
CACTGGGGCCCTTCAGACTATGAAAAGGTTCTAAGGAGGTCTGTGTTGGTGGCTGTGACTGTGGCTGTGCTAGGGTGGTG
AGCCCTGTGGGCTCAGGCGTCAGACTACCTGGATTCAGACCCAGCTCCTGCTTCCAACCTTGGTTTTTTATTCCTAAAAT
GGGTATTGTAATAATACCTACCTTGCTGGGGTGTGGCAAGAATGAAATTAAACAGGGCTTGGCACAGTGAAGCACGGGAA
AGGCTTTCTACAGAGCAGTGACTGTTGTTACTCGCTGTTACACCTTAGGTAATGCGTTTTCCTCTCTGGGTGCCTCCCAT
TTTCTGGCTCAAGTCCCTGCCCAGGATCAAGCTTGGAGGAGGGCCCCGAGGGAGGGGCCACAGAGACTGGGTGAAGAGCA
AGGGTGTTTGTCCCAGGAGCATGGCGAAAATTGCTGCTGGGTGGCCTTGGGAAGCACAAAGGGGACCCAACTAAGGGCCT
GATCCTACTGCCCTGGGGGTGTCAGTGCCAGCCCCCCACAAATCTTTTCTGCCCCCCCCAGGAGGCTGACCAGTGTGTGG
CCTGTGCCCACTATAAGGACCCTCCCTTCTGCGTGGCCCGCTGCCCCAGCGGTGTGAAACCTGACCTCTCCTACATGCCC
ATCTGGAAGTTTCCAGATGAGGAGGGCGCATGCCAGCCTTGCCCCATCAACTGCACCCACTCGTGAGTCCAACGGTCTTT
TCTGCAGAAAGGAGGACTTTCCTTTCAGGGGTCTTTCTGGGGCTCTTACTATAAAAGGGGACCAACTCTCCCTTTGTCAT
ATCTTGTTTCTGATGACAAAAATAACACATTGTTAAAATTGTAAAATTAAAACATGAAATATAAATTAATGCCCTAGCAG
TTCTATCCCCACTGTTAATAATTTGAAATATTTTTCCTCTAGTTATTTTTGTCTGTGCACATTCTAATATGTATATATAA
GTTAACATATATTAATATTATTCTCCAGTTATTTTTATCTGTGCACATTTTAACACACACACACACACACACACACACAC
ACATATGTATTTTTAGACGGAGTTTCACTCTGTCGCCCAGGCTGGAGTGCAGTAGTACAATCTTGGCTCACTGCAGCCTC
CACCTCCTGGGTTTAAGCAATTCTCCTGCTTCCGCCTCCTGAGTAGCTGGGATTACGGGAACGTGCTACCTTGCCTGGCT
AATTTTTGTATTTTTAGTACATAGGATTTCACCATGTTGGCCAGGCTGGTCTCGAACCCCTGACCTCAGGTGATCTGCCA
GCCTCGGTCCCCCAAAGTGTTGGGATTACAGCGGTGAGCCACCATGCCCAGTCATATATTTCTTTTTAACAAATAGAATC
ATAGATCATACATATTGTTTGCAAATTGCTTTTTCTCACTTTCCAGAACCTTGAAATGTTTTTCCATGTTCTAACATGGT
GATCTACCTTATTCTTTTAATTTTTCTTATTTAGTTGTCTTTACACATGAAACACATGAATACATCCTTGTGATAAACAT
TTTCAGTAACATAAAAGTATAAATGTTACAAAGCCAACGTGCCCTTTCACTCAACTCCCTGTCCACCCAGTCTCTCCTGT
CTGCTGGGAGAACCACCGCATTGACTTGTGTGTTCACCCTTCCAGGCTCTTTTCTGCACACTTATATAGACATACTACAT
TTATATTAGGTCGAGTCAAATAAGATTGCTGTTTGTGTAAACCAAAAAGTGTCAAGAGCCTGGGCGCAGTGACTCACACC
TGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGCAGATCACTTGAGATCAGGAGTTCGAGACCAATCTGGCCAACATAGC
GAGACCCCGTCTCTACTAAAAATACAAAAACTAGCCAGGTGTGGTGATGCTGTTCTGCACTTTGCTTTCCCCCCGACTTG
AGGTATCCTTTCTTGTGAGTACAGACGGATCTACCACCTTTATTTTTTTTTTAATTACTCAACCTGTAACATGGATGTAA
TTTCACTTTGTTTTTGAGGGATATTGAGCTTGTTTCCCTGTTTTTGCAGTTTATTGCAATTGAGCTCCACACACAAGTGA
GCCCTCTTTTGTATGCCCCCTAGTGGGAATACAGTGCTGGCAATGTTTATCACAAGGATATATTCATGCATTTCAATTTA
AAGACAACTAAATGAGAAAAATTAAAAGAATATGGATCCAGGCTGGGCATGGTGGCTCACGCCTGTAATCCCAGCACTTT
GGGAGGCCGAGGCAGGCAGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGCAAAACCCCGTCTCTACT
AAAAATACAAAAATTAGCCAGGCGTGGTGGTGGGCGCCTGTAATCCCAGCTATTTGAGAGGTTGAGACAGGAGAATTGCT
TGAACCTGGGCAGCGGAGGTTGCAGTGAGACGAGATTGCACCAGTGCACTCCAACCTGGGCAACACAGTGCAACTCCTTC
TCAAGAAAAAAAAGAAAAAAAAAAAGAATATGGGTCCAGATCCATATGGATCCTAGATCCAGATCACGGTGTTAGAACAT
GGAAAAACATTGCAAGATTCTGCTAAGTGAAAAAAGCATTTGCAAACAGTATGTACAGTCTATATTCAGAGGAGGAACTG
CTGGGTCATAGATGATATTTCATAGGTATTGCCAAACCGTTCTCTGGAGAAGTGGTATGGGTTTACCCTGGGATTCTTCT
ATGGAGGGAATAGTTGAGCTCCCGGGCTTGCTCTTCTGGGTGCCCCTCCCCGCTTCCTATCCACCACAAGGAGCTGCAGG
GGAGCGGGGCATGCCGGTTCCTTGGCTGGAGAAGGAGTCTCCTTGTGAGGTGGTAGAAGGAGCACTGACGGCCTTGAGCC
CAGTTTCTGCCTTTGTCAAATGGGGATAATGACCCAGCCACACCCCTCCCAGGGTTGTTGTGAGGCTGGAAAGGTGGTTC
CCAAGAGGGTGGTTCCCAGAATTGTTGATGAGACTGTTTCTCCTGCAGCTGTGTGGACCTGGATGACAAGGGCTGCCCCG
CCGAGCAGAGAGCCAGGTTGGCCTGGACCCCAGGATGTACCCTTCATTGCCCTTCACTCCCCCACTGGATGCTGGGTGGT
CACTGCTGTAGGGAGGGGACCCCCTGACATATGTCCCTTCCCACCCACTCTTCCACTGTGGAACCTCCTGTCATTTTCCA
CTTCACCAAGTGACAGAGGACCTGCTCAGATGCTGAGGGGAGGGGACTGCAAGGAAAGATGGCTAGGAAACCCAGTCCCT
CCACACCCTAGAGTAACTTGATGCCTTGTGAGGGACACAGGCAAAGTTCAATTCCTTGGAAGTCAAGGGAGACTGAGAAG
AGTACAGCTGCAGCACTGAGGGAGTGATGAATTCTTAACTGGGGATGGTGGGAGGCTTCGAGTGGGAGGTGGCATTTGAG
CTAGGCTTTGAGAGAGGAGCAGGTATTGCACTTGCATTTAGGTAGAAAGCATTGGGGTGCAAGGTGACACTGGAGGGGGA
GGCATCAGGAAATCCAGGATGTCTTCAAAGTTCTGGTGTCGGGGGCTGTTGAGTAAGCACAGGAATAAGGGGGTCAAGTT
AGAGTCAGGGTGGGGTCTGACCTGGATGCCATAGGACCTGATCCCCAAGCCACAGGGTGGGACTTGACTGGGCAGTGGGG
ACCTTTGGAAAGGACTTTGGGGAGAAAAACAGACTGGAGTCTGTCTTAGGCGATCATCGGTCCGTGAAATGAGCATGTGT
TACAGGCTTGGTATGTACCAGACCCTGTGCTAAGCAAGGGGGTATGGAGAGGAGAGGGTGACAAGAATATTGGATCAACA
CCCGGGAGCTCCATCTATCCCAGGATGCACTATCTTTTTTTTATTTTTTTGAGACGGAGTCTCACTCTGCCTGCAGGCTG
GAGTGCAGTGGCTCCATCTCGGTTCACTGCAACCTCTGCCTCCTGGGTTCAAGCGCTTCTTGTGCCTCAGCCTCCCAAGT
AGCTGGGATTACAGGCACATGCCACCACACCCAGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTGGCC
AGGATGGTCTCGATCTCTTGACCTCAAGATCCGCCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGACATGAGCCACCG
TGCCCAGCCAGATACGCTATCTTTTTATTGAGTGATTGAGACAGGGTCTTGCTCTCTTGTCCAGTCTTGAATGTGGTGGT
GTAATCACAGGCTCACTGCAGCCTTGACCTCCTGGGCTCAAGTTACCCTTCTGCAGTAGCTGGGACTATAGGAGCGTGCC
ACCACGCCTGGGTAATTTAAAAAATTTTTTTTGTATAGACAGGGTCTCACTATGTTGCCCGAGCTGGTCTCAAACTCGTG
GGCTCAAGTGATCCTCCAGTTTTGGCCTCCCAAAATGTTGGGATCACAGGAGTGAGCCACCACTCCTGGCGATGAGCCAA
GTCTTTTTTTTTTTTTTTTTTTTTTGATATGGAGTCTTGCTCTGTTGCCCAGGCTGGAGTGCAATGACACGATCTTGGCT
CACTGCAACCTCTGCCTCCCAGGTTCAAGCAGTTCAAGCAATCCTCCTGTCTCAGCCCCCCAGTAGCTGGGATTACAGGC
ATGCGCTACCACGTCCGGCTAATTTTTGTATTTTTAGTAGAGATGAGGTTTTGCCATGTTGGCCAGGCTGGTCTTGAACT
GCTGACCTCAGGTGATCCACCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCATCGTGCCTGGCGGAGCC
GAGTCTTAAAAGATGACCCTGTGGAGAAATGGTGGTCCAGGCTGAAGGGACAGCCTATGCAAACACTGGGAGGTGTGGAA
AATCATGACCTGTGGGTGGAAATTTTGGCTAGAACATCAAAATCATCAGGTGTACATTCCTGTACCCATGCAGCAGTCAG
AATCTCTGGGGGTGGGGCCCCAAAATTGTATGCATACAGACTGTGTGCTGATTTGTGATATTACTTAGGATTTTTTGACT
TTACAATGGTGGAAAAGCAATAATATACATTCAGTATAAACCGTACTTTGAATACCCATACAGCCATTCTGTTTTTCACT
TTTATTTTTATTTATTTATTTATTTATTATTTATTTTGAGATGTCATTTTGCTGTTGTTACCCAGGCTGGAGTGCAATGG
CGCAGTCTTGGCTCACCGCAACCTCCACCTCTCAGGTTCAAACGATTCTCCTGCTTCAGCCTCCAGAGTGGCTGGGATTA
CAGGCAGGCACCACCACACCCGGCTAATTTTGTATTTTTAGTAGAGACGGGGTTTCTCCATGTTAGTCAGGCTGGTCTCG
AACTCGAGAGCTCAGGTGATCTGCCCATCTCAGCCTCAAGCCACCATGCCCAGCCCTACTTTCAGTATTCAATAAATTAC
ATAGCCAGGCACCGTGGCTCACACCTGTAATCCCAGCACTTTAGGAGGCCAAGGTGGGAGGATCCTTTGAGGCCAGAAGC
TCGAGACCAGCCTGGGCAACATAGTGAGACCCCATTTCTACAAAAAATAAAAAAACTAGCTGAGTGTGGTGGCGTGTGTC
TGTAGTCCCAGCTACTTGGGCAGCTGAGGTGGAAAGACTGCTTGAGCCCAGAGGTCAGGGCTGCAGTGGGCCATGATCTC
ACCACTGCACTCAGCCTGGGCAACACAGCAAGGCCCTGTCTCAAAAATAAATAAATAAATAACACAAACTTATTTAACAG
TTTACTATAAAATAGGCTTTGTGTCAGATGATTCTGCCCAACTGTAAGCTGCTGGCAGTGTAAATGTTCTGAGCACGTGT
AAGCCAGGCTAGGTGTCTTAAATGCATTTTCAGTTTCAACTTAGAATTGGTTTATCAGGACGTAGCCCCTTGGTGTTGAG
GGGCATGTGTATTAACAGTCTCCTTAGTGACTTTTTTTTTTTTGAGATGGAGTCTTGCACTGGCCGTAGTGCAGTGGCAC
AATCTCAGCTCACTGCAACCTCTTGTCTCCCGGGTTCAAGCGATTCTCCTGCCTCAGTCTCCCAAGTAGCTGGGATTACA
GGCACCCACACCACGCCCAGCTAATTTTTGTGTGTGTGTATTTTTAGTAGAGACGGGGGTTTCACTATGTTGGCCAGGCT
GGTCTCGAACTCCTGACCTTGTGATCTGCCCACCTCAGACTCTCAAAGTGCTAGGATTCCAGGCATGAGCCACCGCGCCC
AGAGTCCTTAGTGATTTTTACACCATGAATTGTTGAAGCCCTAAGCCAGAGCCAAGGGCAAGAGTATAGAGAATCTGGAG
ATGCGGAGAGGGTTCTGATTGCCTACAAGGAGTTTGGACTTTATTGTGGAGGCAGCGGGGAGCCAAGGCAGGTTTTAGAG
TAGGAGAGGGTCCAAGCCTGTGGGTCACCCTTCCGACTTCCCTTTCCGAATGCCAAACACCTTCATGTCCCCCGTGGGCC
CCCTTTGTCCCTCCCACCCCAAACTAGCCCTCAATCCCTGACCCTGGCTTCCGCCCCCAGCCCTCTGACGTCCATCATCT
CTGCGGTGGTTGGCATTCTGCTGGTCGTGGTCTTGGGGGTGGTCTTTGGGATCCTCATCAAGCGACGGCAGCAGAAGATC
CGGAAGTACACGATGCGGAGACTGCTGCAGGAAACGGAGGTGAGGCGGGGTGAAGTCCTCCCAGCCCGCGTGGGGTCTGC
ACCGGCCCCCGGCACTGACCCACCACCCCCTCACCCCAGCTGGTGGAGCCGCTGACACCTAGCGGAGCGATGCCCAACCA
GGCGCAGATGCGGATCCTGAAAGAGACGGAGCTGAGGAAGGTGAAGGTGCTTGGATCTGGCGCTTTTGGCACAGTCTACA
AGGTCAGGGCCAGGTCCTGGGGTGGGCGGCCCCAGAGGATGGGGGCGGTGCCTGGAGGGGTGTGGTCGGCAGTTCTGATG
GGAGGGGCAAGAGCTGGAGGCAGTGTTTGGGGGAGGGCAGTTACAGCGGAGAAGGGAGCGGGGCCAAGCCCTAGGGTGGT
GAAGGATGTTTGGAGGACAAGTAATGATCTCCTGGAAGGCAGGTAGGATCCAGCCCACGCTCTTCTCACTCATATCCTCC
TCTTTCTGCCCAGGGCATCTGGATCCCTGATGGGGAGAATGTGAAAATTCCAGTGGCCATCAAAGTGTTGAGGGAAAACA
CATCCCCCAAAGCCAACAAAGAAATCTTAGACGTAAGCCCCTCCACCCTCTCCTGCTAGGAGGACAGGAAGGACCCCATG
GCTGCAGGTCTGGGCTCTGGTCTCTCTTCATTGGGGTTTGGGGAGATATGACTCCCGCAAACCTAGACTATTTTTTTGGA
GACGGAGTCTTGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGTTATCTCGGCTCACTGCAACCTCCACCTCCTGGACTCA
AGCGATTTTCATGCCTCAGGCTCCTGAGTAGCTGGGATTACAAGCGCCCGCTAATTTTTTTTTTTTTTTTGAGACAGAGT
CTCGCTCTGTCACCCAGGCTAGAGTGAAATGGTGCGGTCTCAGCTCAGCCTCCCAGGTTAAAGCGATTCTTCTCCCTCAG
TCTCCTGAGTAGCTGGGATTACAGGCGCGAGCCACCACGCCCGGCTAATTTTTGTATTTTTAGTAGAGATGGGATTTCAC
CATGTTGGCCAGGTTGGTGTCAAACTCCTGACCTCATGATCCGCCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGTG
TGAGCCACCGTGCCCGGCCTAATCTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGTCCAGGCTGGTACTTTGAG
CCTTCACAGGCTGTGGGCCATGGCTGTGGTTTGTGATGGTTGGGAGGCTGTGTGGTGTTTGGGGGTGTGTGGTCTCCCAT
ACCCTCTCAGCGTACCCTTGTCCCCAGGAAGCATACGTGATGGCTGGTGTGGGCTCCCCATATGTCTCCCGCCTTCTGGG
CATCTGCCTGACATCCACGGTGCAGCTGGTGACACAGCTTATGCCCTATGGCTGCCTCTTAGACCATGTCCGGGAAAACC
GCGGACGCCTGGGCTCCCAGGACCTGCTGAACTGGTGTATGCAGATTGCCAAGGTATGCACCTGGGCTCTTTGCAGGTCT
CTCCGGAGCAAACCCCTATGTCCACAAGGGGCTAGGATGGGGACTCTTGCTGGGCATGTGGCCAGGCCCAGGCCCTCCCA
GAAGGTCTACATGGGTGCTTCCCATTCCAGGGGATGAGCTACCTGGAGGATGTGCGGCTCGTACACAGGGACTTGGCCGC
TCGGAACGTGCTGGTCAAGAGTCCCAACCATGTCAAAATTACAGACTTCGGGCTGGCTCGGCTGCTGGACATTGACGAGA
CAGAGTACCATGCAGATGGGGGCAAGGTTAGGTGAAGGACCAAGGAGCAGAGGAGGCTGGGTGGAGTGGTGTCTAGCCCA
TGGGAGAACTCTGAGTGGCCACCTCCCCACAACACACAGTTGGAGGACTTCCTCTTCTGCCCTCCCAGGTGCCCATCAAG
TGGATGGCGCTGGAGTCCATTCTCCGCCGGCGGTTCACCCACCAGAGTGATGTGTGGAGTTATGGTGTGTGATGGGGGGT
GTTGGGAGGGGTGGGTGAGGAGCCATGGCTGGAGGGAGGATGAGAGCTGGGATGGGGAGAATTACGGGGCCACCTCAGCA
TGTGAAGGGAGGGAAGGGGCTGCCTGTGCCCCACCTTGCAGGGTCTGTGCACTTCCCAGGATTAGGGAAAGACCGGGTAG
GGTCTGTCTCCTGGCATCACATCTCCCCCTGCTACCTGCCATGATGCTAGACTCCTGAGCAGAACCTCTGGCTCAGTACA
CTAAAGCTCCCTCTGGCCCTCCCACTCCTGACCCTGTCTCTGCCTTAGGTGTGACTGTGTGGGAGCTGATGACTTTTGGG
GCCAAACCTTACGATGGGATCCCAGCCCGGGAGATCCCTGACCTGCTGGAAAAGGGGGAGCGGCTGCCCCAGCCCCCCAT
CTGCACCATTGATGTCTACATGATCATGGTCAAATGTGCGTGGCTGAGCTGTGCTGGCTGCCTGGAGGAGGGTGGGAGGT
CCTGGGTGGAGGAGCCCACAAGGGGCATGAAAGGGGACCAGGATGTATGTAGACCCAGGAGCCCTAGTATGTTAGGAGCC
TCAAAACCTTCTTGTATCCCTTTTACAGTCAAAGTCCAAAGCCACTCTTGAGGAACACTCTTGTACAAAATTAAGCTGGG
CACAGTGGCTCATGCCTGTAATCCCAGTACTTTTGGAGGCTGAGGTGGGAGGATCCCTTGAAGCCAGGAGTTCAAGACCA
GCCTGGGCAACATAGTGAGATCCTATCTCTACAAAAAATAAAAAAATTATCTGGGTGTGGTGGTGTGTGCCAGTAGTCCC
AGCTACTCAGGAGAGGCTGAGGCAGGAAGATCACTTGAGCCTAGTTTAAGGTTGCAGTAAGCTATGATTGCACCACTGAA
ATCCAGCCTGGGTGACAGAGCGAAACCTCATCTCAAAAAAATAAAAAAGCAAACAAAAAGAAAAAAAAAATTAAAAGGGA
AACTAGAAGAGATGCCAAAGGTTCTGGCTGAAGACCCCAGAGTCTGGTGCTACTTCTCTACCACCTGAGGGCTTTGGGCT
GTCCCTTGGGACTGTCTAGACCAGACTGGAGGGGGAGTGGGAGGGGAGAGGCAGCAAGCACACAGGGCCTGGGACTAGCA
TGCTGACCTCCCTCCTGCCCCAGGTTGGATGATTGACTCTGAATGTCGGCCAAGATTCCGGGAGTTGGTGTCTGAATTCT
CCCGCATGGCCAGGGACCCCCAGCGCTTTGTGGTCATCCAGGTACTGGGCCTCTGTGCCCCATCCCTGCCTGTGGCTAAG
AGCACCCTCCTGCAGAGGGTGGGAAGGAGAGATGAGTCCAGTATGCCAGGCCCCTCACGGAAGGCTGCATGCTGGGCTGG
GGAGGGGCCACCATCCTGCCTCTCCTTCCTCCACAGAATGAGGACTTGGGCCCAGCCAGTCCCTTGGACAGCACCTTCTA
CCGCTCACTGCTGGAGGACGATGACATGGGGGACCTGGTGGATGCTGAGGAGTATCTGGTACCCCAGCAGGGCTTCTTCT
GTCCAGACCCTGCCCCGGGCGCTGGGGGCATGGTCCACCACAGGCACCGCAGCTCATCTACCAGGGTCAGTGCCCTCGGT
CACACTGTGTGGCTGTCTGCTTACCTCCCCCAACCCCGGTGGACTAGGGTCCCTTTCTCTGATGTTCCCTCAACTGTCAC
CTCTCAAGGAAACCCCATTATCCCTACAAAAAATTCTTACTGCCTTCCAACCCCTGTGACCCCATTCTCTCCACGGTGAC
TGTGTCATACCCCAAAGGTGACCTCTGTTTTTCTCCTGTGACCCTGTCACCTTCCATGGAGTCCCCATCCCAGATCCGTG
AGTGACCCCCATCATGACTTTCTTTCTTGTCCCCAGAGTGGCGGTGGGGACCTGACACTAGGGCTGGAGCCCTCTGAAGA
GGAGGCCCCCAGGTCTCCACTGGCACCCTCCGAAGGGGCTGGCTCCGATGTATTTGATGGTGACCTGGGAATGGGGGCAG
CCAAGGGGCTGCAAAGCCTCCCCACACATGACCCCAGCCCTCTACAGCGGTACAGTGAGGACCCCACAGTACCCCTGCCC
TCTGAGACTGATGGCTACGTTGCCCCCCTGACCTGCAGCCCCCAGCCTGGTATGGAGTCCAGTCTAAGCAGAGAGACTGA
TGGGCAGGGGAGGTGGGACCTTCAGCCCAGGGTCCACTGTGGGGGCAGAGGGAGTGGCAGAGACACCGGGGTTCCTTCCC
CTAATGGGTCACCTTCTCTTGACCTTTCAGAATATGTGAACCAGCCAGATGTTCGGCCCCAGCCCCCTTCGCCCCGAGAG
GGCCCTCTGCCTGCTGCCCGACCTGCTGGTGCCACTCTGGAAAGGCCCAAGACTCTCTCCCCAGGGAAGAATGGGGTCGT
CAAAGACGTTTTTGCCTTTGGGGGTGCCGTGGAGAACCCCGAGTACTTGACACCCCAGGGAGGAGCTGCCCCTCAGCCCC
ACCCTCCTCCTGCCTTCAGCCCAGCCTTCGACAACCTCTATTACTGGGACCAGGACCCACCAGAGCGGGGGGCTCCACCC
AGCACCTTCAAAGGGACACCTACGGCAGAGAACCCAGAGTACCTGGGTCTGGACGTGCCAGTGTGAACCAGAAGGCCAAG
TCCGCAGAAGCCCTGATGTGTCCTCAGGGAGCAGGGAAGGCCTGACTTCTGCTGGCATCAAGAGGTGGGAGGGCCCTCCG
ACCACTTCCAGGGGAACCTGCCATGCCAGGAACCTGTCCTAAGGAACCTTCCTTCCTGCTTGAGTTCCCAGATGGCTGGA
AGGGGTCCAGCCTCGTTGGAAGAGGAACAGCACTGGGGAGTCTTTGTGGATTCTGAGGCCCTGCCCAATGAGACTCTAGG
GTCCAGTGGATGCCACAGCCCAGCTTGGCCCTTTCCTTCCAGATCCTGGGTACTGAAAGCCTTAGGGAAGCTGGCCTGAG
AGGGGAAGCGGCCCTAAGGGAGTGTCTAAGAACAAAAGCGACCCATTCAGAGACTGTCCCTGAAACCTAGTACTGCCCCC
CATGAGGAAGGAACAGCAATGGTGTCAGTATCCAGGCTTTGTACAGAGTGCTTTTCTGTTTAGTTTTTACTTTTTTTGTT
TTGTTTTTTTAAAGATGAAATAAAGACCCAGGGGGAGAATGGGTGTTGTATGGGGAGGCAAGTGTGGGGGGTCCTTCTCC
ACACCCACTTTGTCCATTTGCAAATATATTTTGGAAAACAGCT
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Primary source |
RefSeq : NM_004448.2 (GI:54792095)
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Name |
V-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) (ERBB2), transcript variant 1
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Type of transcript |
mRNA
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Organism |
Homo sapiens
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Length |
4624 nt
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Map |
17q21.1
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Location |
Chromosome 17 (NC_000017.10) strand : +
37856253...37856563 | 37863242...37863393 | 37864573...37864786 | 37865570...37865704 |
37866065...37866133 | 37866338...37866453 | 37866592...37866733 | 37868180...37868299 |
37868574...37868700 | 37871538...37871611 | 37871698...37871788 | 37871992...37872191 |
37872553...37872685 | 37872767...37872857 | 37873572...37873732 | 37876039...37876086 |
37879571...37879709 | 37879790...37879912 | 37880164...37880262 | 37880978...37881163 |
37881301...37881456 | 37881579...37881654 | 37881959...37882105 | 37882814...37882911 |
37883067...37883255 | 37883547...37883799 | 37883941...37884914 |
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Exon(s) |
Start |
End |
Length |
is coding |
Exon 5
|
1
|
311
|
311
|
1
|
Exon 6
|
312
|
463
|
152
|
1
|
Exon 7
|
464
|
677
|
214
|
1
|
Exon 8
|
678
|
812
|
135
|
1
|
Exon 9
|
813
|
881
|
69
|
1
|
Exon 10
|
882
|
997
|
116
|
1
|
Exon 11
|
998
|
1139
|
142
|
1
|
Exon 12
|
1140
|
1259
|
120
|
1
|
Exon 13
|
1260
|
1386
|
127
|
1
|
Exon 14
|
1387
|
1460
|
74
|
1
|
Exon 15
|
1461
|
1551
|
91
|
1
|
Exon 16
|
1552
|
1751
|
200
|
1
|
Exon 17
|
1752
|
1884
|
133
|
1
|
Exon 18
|
1885
|
1975
|
91
|
1
|
Exon 19
|
1976
|
2136
|
161
|
1
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Exon 20
|
2137
|
2184
|
48
|
1
|
Exon 21
|
2185
|
2323
|
139
|
1
|
Exon 22
|
2324
|
2446
|
123
|
1
|
Exon 23
|
2447
|
2545
|
99
|
1
|
Exon 24
|
2546
|
2731
|
186
|
1
|
Exon 25
|
2732
|
2887
|
156
|
1
|
Exon 26
|
2888
|
2963
|
76
|
1
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Exon 27
|
2964
|
3110
|
147
|
1
|
Exon 28
|
3111
|
3208
|
98
|
1
|
Exon 29
|
3209
|
3397
|
189
|
1
|
Exon 30
|
3398
|
3650
|
253
|
1
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Exon 31
|
3651
|
4624
|
974
|
1
|
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ID |
Class |
Location |
Mutation |
Length |
is synonymous |
Source |
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Primary source |
NCBI : CCDS32642
|
Nucleotide |
ERBB2, mRNA isoform 1[NM_004448.2] : 239...4006
|
Length |
3768
|
Location |
Chromosome 17 (NC_000017.10) strand : +
37856491...37856563 | 37863242...37863393 | 37864573...37864786 | 37865570...37865704 |
37866065...37866133 | 37866338...37866453 | 37866592...37866733 | 37868180...37868299 |
37868574...37868700 | 37871538...37871611 | 37871698...37871788 | 37871992...37872191 |
37872553...37872685 | 37872767...37872857 | 37873572...37873732 | 37876039...37876086 |
37879571...37879709 | 37879790...37879912 | 37880164...37880262 | 37880978...37881163 |
37881301...37881456 | 37881579...37881654 | 37881959...37882105 | 37882814...37882911 |
37883067...37883255 | 37883547...37883799 | 37883941...37884296 |
|
Start codon |
1
|
Translation |
NP_004439.2 |
|
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|
1 |
GGAGGAGGTG |
GAGGAGGAGG |
GCTGCTTGAG |
GAAGTATAAG |
AATGAAGTTG |
TGAAGCTGAG |
ATTCCCCTCC |
ATTGGGACCG |
|
81 |
GAGAAACCAG |
GGGAGCCCCC |
CGGGCAGCCG |
CGCGCCCCTT |
CCCACGGGGC |
CCTTTACTGC |
GCCGCGCGCC |
CGGCCCCCAC |
|
161 |
CCCTCGCAGC |
ACCCCGCGCC |
CCGCGCCCTC |
CCAGCCGGGT |
CCAGCCGGAG |
CCATGGGGCC |
GGAGCCGCAG |
TGAGCACCAT |
|
241 |
GGAGCTGGCG |
GCCTTGTGCC |
GCTGGGGGCT |
CCTCCTCGCC |
CTCTTGCCCC |
CCGGAGCCGC |
GAGCACCCAA |
GTGTGCACCG |
|
321 |
GCACAGACAT |
GAAGCTGCGG |
CTCCCTGCCA |
GTCCCGAGAC |
CCACCTGGAC |
ATGCTCCGCC |
ACCTCTACCA |
GGGCTGCCAG |
|
401 |
GTGGTGCAGG |
GAAACCTGGA |
ACTCACCTAC |
CTGCCCACCA |
ATGCCAGCCT |
GTCCTTCCTG |
CAGGATATCC |
AGGAGGTGCA |
|
481 |
GGGCTACGTG |
CTCATCGCTC |
ACAACCAAGT |
GAGGCAGGTC |
CCACTGCAGA |
GGCTGCGGAT |
TGTGCGAGGC |
ACCCAGCTCT |
|
561 |
TTGAGGACAA |
CTATGCCCTG |
GCCGTGCTAG |
ACAATGGAGA |
CCCGCTGAAC |
AATACCACCC |
CTGTCACAGG |
GGCCTCCCCA |
|
641 |
GGAGGCCTGC |
GGGAGCTGCA |
GCTTCGAAGC |
CTCACAGAGA |
TCTTGAAAGG |
AGGGGTCTTG |
ATCCAGCGGA |
ACCCCCAGCT |
|
721 |
CTGCTACCAG |
GACACGATTT |
TGTGGAAGGA |
CATCTTCCAC |
AAGAACAACC |
AGCTGGCTCT |
CACACTGATA |
GACACCAACC |
|
801 |
GCTCTCGGGC |
CTGCCACCCC |
TGTTCTCCGA |
TGTGTAAGGG |
CTCCCGCTGC |
TGGGGAGAGA |
GTTCTGAGGA |
TTGTCAGAGC |
|
881 |
CTGACGCGCA |
CTGTCTGTGC |
CGGTGGCTGT |
GCCCGCTGCA |
AGGGGCCACT |
GCCCACTGAC |
TGCTGCCATG |
AGCAGTGTGC |
|
961 |
TGCCGGCTGC |
ACGGGCCCCA |
AGCACTCTGA |
CTGCCTGGCC |
TGCCTCCACT |
TCAACCACAG |
TGGCATCTGT |
GAGCTGCACT |
|
1041 |
GCCCAGCCCT |
GGTCACCTAC |
AACACAGACA |
CGTTTGAGTC |
CATGCCCAAT |
CCCGAGGGCC |
GGTATACATT |
CGGCGCCAGC |
|
1121 |
TGTGTGACTG |
CCTGTCCCTA |
CAACTACCTT |
TCTACGGACG |
TGGGATCCTG |
CACCCTCGTC |
TGCCCCCTGC |
ACAACCAAGA |
|
1201 |
GGTGACAGCA |
GAGGATGGAA |
CACAGCGGTG |
TGAGAAGTGC |
AGCAAGCCCT |
GTGCCCGAGT |
GTGCTATGGT |
CTGGGCATGG |
|
1281 |
AGCACTTGCG |
AGAGGTGAGG |
GCAGTTACCA |
GTGCCAATAT |
CCAGGAGTTT |
GCTGGCTGCA |
AGAAGATCTT |
TGGGAGCCTG |
|
1361 |
GCATTTCTGC |
CGGAGAGCTT |
TGATGGGGAC |
CCAGCCTCCA |
ACACTGCCCC |
GCTCCAGCCA |
GAGCAGCTCC |
AAGTGTTTGA |
|
1441 |
GACTCTGGAA |
GAGATCACAG |
GTTACCTATA |
CATCTCAGCA |
TGGCCGGACA |
GCCTGCCTGA |
CCTCAGCGTC |
TTCCAGAACC |
|
1521 |
TGCAAGTAAT |
CCGGGGACGA |
ATTCTGCACA |
ATGGCGCCTA |
CTCGCTGACC |
CTGCAAGGGC |
TGGGCATCAG |
CTGGCTGGGG |
|
1601 |
CTGCGCTCAC |
TGAGGGAACT |
GGGCAGTGGA |
CTGGCCCTCA |
TCCACCATAA |
CACCCACCTC |
TGCTTCGTGC |
ACACGGTGCC |
|
1681 |
CTGGGACCAG |
CTCTTTCGGA |
ACCCGCACCA |
AGCTCTGCTC |
CACACTGCCA |
ACCGGCCAGA |
GGACGAGTGT |
GTGGGCGAGG |
|
1761 |
GCCTGGCCTG |
CCACCAGCTG |
TGCGCCCGAG |
GGCACTGCTG |
GGGTCCAGGG |
CCCACCCAGT |
GTGTCAACTG |
CAGCCAGTTC |
|
1841 |
CTTCGGGGCC |
AGGAGTGCGT |
GGAGGAATGC |
CGAGTACTGC |
AGGGGCTCCC |
CAGGGAGTAT |
GTGAATGCCA |
GGCACTGTTT |
|
1921 |
GCCGTGCCAC |
CCTGAGTGTC |
AGCCCCAGAA |
TGGCTCAGTG |
ACCTGTTTTG |
GACCGGAGGC |
TGACCAGTGT |
GTGGCCTGTG |
|
2001 |
CCCACTATAA |
GGACCCTCCC |
TTCTGCGTGG |
CCCGCTGCCC |
CAGCGGTGTG |
AAACCTGACC |
TCTCCTACAT |
GCCCATCTGG |
|
2081 |
AAGTTTCCAG |
ATGAGGAGGG |
CGCATGCCAG |
CCTTGCCCCA |
TCAACTGCAC |
CCACTCCTGT |
GTGGACCTGG |
ATGACAAGGG |
|
2161 |
CTGCCCCGCC |
GAGCAGAGAG |
CCAGCCCTCT |
GACGTCCATC |
ATCTCTGCGG |
TGGTTGGCAT |
TCTGCTGGTC |
GTGGTCTTGG |
|
2241 |
GGGTGGTCTT |
TGGGATCCTC |
ATCAAGCGAC |
GGCAGCAGAA |
GATCCGGAAG |
TACACGATGC |
GGAGACTGCT |
GCAGGAAACG |
|
2321 |
GAGCTGGTGG |
AGCCGCTGAC |
ACCTAGCGGA |
GCGATGCCCA |
ACCAGGCGCA |
GATGCGGATC |
CTGAAAGAGA |
CGGAGCTGAG |
|
2401 |
GAAGGTGAAG |
GTGCTTGGAT |
CTGGCGCTTT |
TGGCACAGTC |
TACAAGGGCA |
TCTGGATCCC |
TGATGGGGAG |
AATGTGAAAA |
|
2481 |
TTCCAGTGGC |
CATCAAAGTG |
TTGAGGGAAA |
ACACATCCCC |
CAAAGCCAAC |
AAAGAAATCT |
TAGACGAAGC |
ATACGTGATG |
|
2561 |
GCTGGTGTGG |
GCTCCCCATA |
TGTCTCCCGC |
CTTCTGGGCA |
TCTGCCTGAC |
ATCCACGGTG |
CAGCTGGTGA |
CACAGCTTAT |
|
2641 |
GCCCTATGGC |
TGCCTCTTAG |
ACCATGTCCG |
GGAAAACCGC |
GGACGCCTGG |
GCTCCCAGGA |
CCTGCTGAAC |
TGGTGTATGC |
|
2721 |
AGATTGCCAA |
GGGGATGAGC |
TACCTGGAGG |
ATGTGCGGCT |
CGTACACAGG |
GACTTGGCCG |
CTCGGAACGT |
GCTGGTCAAG |
|
2801 |
AGTCCCAACC |
ATGTCAAAAT |
TACAGACTTC |
GGGCTGGCTC |
GGCTGCTGGA |
CATTGACGAG |
ACAGAGTACC |
ATGCAGATGG |
|
2881 |
GGGCAAGGTG |
CCCATCAAGT |
GGATGGCGCT |
GGAGTCCATT |
CTCCGCCGGC |
GGTTCACCCA |
CCAGAGTGAT |
GTGTGGAGTT |
|
2961 |
ATGGTGTGAC |
TGTGTGGGAG |
CTGATGACTT |
TTGGGGCCAA |
ACCTTACGAT |
GGGATCCCAG |
CCCGGGAGAT |
CCCTGACCTG |
|
3041 |
CTGGAAAAGG |
GGGAGCGGCT |
GCCCCAGCCC |
CCCATCTGCA |
CCATTGATGT |
CTACATGATC |
ATGGTCAAAT |
GTTGGATGAT |
|
3121 |
TGACTCTGAA |
TGTCGGCCAA |
GATTCCGGGA |
GTTGGTGTCT |
GAATTCTCCC |
GCATGGCCAG |
GGACCCCCAG |
CGCTTTGTGG |
|
3201 |
TCATCCAGAA |
TGAGGACTTG |
GGCCCAGCCA |
GTCCCTTGGA |
CAGCACCTTC |
TACCGCTCAC |
TGCTGGAGGA |
CGATGACATG |
|
3281 |
GGGGACCTGG |
TGGATGCTGA |
GGAGTATCTG |
GTACCCCAGC |
AGGGCTTCTT |
CTGTCCAGAC |
CCTGCCCCGG |
GCGCTGGGGG |
|
3361 |
CATGGTCCAC |
CACAGGCACC |
GCAGCTCATC |
TACCAGGAGT |
GGCGGTGGGG |
ACCTGACACT |
AGGGCTGGAG |
CCCTCTGAAG |
|
3441 |
AGGAGGCCCC |
CAGGTCTCCA |
CTGGCACCCT |
CCGAAGGGGC |
TGGCTCCGAT |
GTATTTGATG |
GTGACCTGGG |
AATGGGGGCA |
|
3521 |
GCCAAGGGGC |
TGCAAAGCCT |
CCCCACACAT |
GACCCCAGCC |
CTCTACAGCG |
GTACAGTGAG |
GACCCCACAG |
TACCCCTGCC |
|
3601 |
CTCTGAGACT |
GATGGCTACG |
TTGCCCCCCT |
GACCTGCAGC |
CCCCAGCCTG |
AATATGTGAA |
CCAGCCAGAT |
GTTCGGCCCC |
|
3681 |
AGCCCCCTTC |
GCCCCGAGAG |
GGCCCTCTGC |
CTGCTGCCCG |
ACCTGCTGGT |
GCCACTCTGG |
AAAGGCCCAA |
GACTCTCTCC |
|
3761 |
CCAGGGAAGA |
ATGGGGTCGT |
CAAAGACGTT |
TTTGCCTTTG |
GGGGTGCCGT |
GGAGAACCCC |
GAGTACTTGA |
CACCCCAGGG |
|
3841 |
AGGAGCTGCC |
CCTCAGCCCC |
ACCCTCCTCC |
TGCCTTCAGC |
CCAGCCTTCG |
ACAACCTCTA |
TTACTGGGAC |
CAGGACCCAC |
|
3921 |
CAGAGCGGGG |
GGCTCCACCC |
AGCACCTTCA |
AAGGGACACC |
TACGGCAGAG |
AACCCAGAGT |
ACCTGGGTCT |
GGACGTGCCA |
|
4001 |
GTGTGAACCA |
GAAGGCCAAG |
TCCGCAGAAG |
CCCTGATGTG |
TCCTCAGGGA |
GCAGGGAAGG |
CCTGACTTCT |
GCTGGCATCA |
|
4081 |
AGAGGTGGGA |
GGGCCCTCCG |
ACCACTTCCA |
GGGGAACCTG |
CCATGCCAGG |
AACCTGTCCT |
AAGGAACCTT |
CCTTCCTGCT |
|
4161 |
TGAGTTCCCA |
GATGGCTGGA |
AGGGGTCCAG |
CCTCGTTGGA |
AGAGGAACAG |
CACTGGGGAG |
TCTTTGTGGA |
TTCTGAGGCC |
|
4241 |
CTGCCCAATG |
AGACTCTAGG |
GTCCAGTGGA |
TGCCACAGCC |
CAGCTTGGCC |
CTTTCCTTCC |
AGATCCTGGG |
TACTGAAAGC |
|
4321 |
CTTAGGGAAG |
CTGGCCTGAG |
AGGGGAAGCG |
GCCCTAAGGG |
AGTGTCTAAG |
AACAAAAGCG |
ACCCATTCAG |
AGACTGTCCC |
|
4401 |
TGAAACCTAG |
TACTGCCCCC |
CATGAGGAAG |
GAACAGCAAT |
GGTGTCAGTA |
TCCAGGCTTT |
GTACAGAGTG |
CTTTTCTGTT |
|
4481 |
TAGTTTTTAC |
TTTTTTTGTT |
TTGTTTTTTT |
AAAGATGAAA |
TAAAGACCCA |
GGGGGAGAAT |
GGGTGTTGTA |
TGGGGAGGCA |
|
4561 |
AGTGTGGGGG |
GTCCTTCTCC |
ACACCCACTT |
TGTCCATTTG |
CAAATATATT |
TTGGAAAACA |
GCTA |
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>gi|54792095|ref|NM_004448.2|V-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) (ERBB2), transcript variant 1
GGAGGAGGTGGAGGAGGAGGGCTGCTTGAGGAAGTATAAGAATGAAGTTGTGAAGCTGAGATTCCCCTCCATTGGGACCG
GAGAAACCAGGGGAGCCCCCCGGGCAGCCGCGCGCCCCTTCCCACGGGGCCCTTTACTGCGCCGCGCGCCCGGCCCCCAC
CCCTCGCAGCACCCCGCGCCCCGCGCCCTCCCAGCCGGGTCCAGCCGGAGCCATGGGGCCGGAGCCGCAGTGAGCACCAT
GGAGCTGGCGGCCTTGTGCCGCTGGGGGCTCCTCCTCGCCCTCTTGCCCCCCGGAGCCGCGAGCACCCAAGTGTGCACCG
GCACAGACATGAAGCTGCGGCTCCCTGCCAGTCCCGAGACCCACCTGGACATGCTCCGCCACCTCTACCAGGGCTGCCAG
GTGGTGCAGGGAAACCTGGAACTCACCTACCTGCCCACCAATGCCAGCCTGTCCTTCCTGCAGGATATCCAGGAGGTGCA
GGGCTACGTGCTCATCGCTCACAACCAAGTGAGGCAGGTCCCACTGCAGAGGCTGCGGATTGTGCGAGGCACCCAGCTCT
TTGAGGACAACTATGCCCTGGCCGTGCTAGACAATGGAGACCCGCTGAACAATACCACCCCTGTCACAGGGGCCTCCCCA
GGAGGCCTGCGGGAGCTGCAGCTTCGAAGCCTCACAGAGATCTTGAAAGGAGGGGTCTTGATCCAGCGGAACCCCCAGCT
CTGCTACCAGGACACGATTTTGTGGAAGGACATCTTCCACAAGAACAACCAGCTGGCTCTCACACTGATAGACACCAACC
GCTCTCGGGCCTGCCACCCCTGTTCTCCGATGTGTAAGGGCTCCCGCTGCTGGGGAGAGAGTTCTGAGGATTGTCAGAGC
CTGACGCGCACTGTCTGTGCCGGTGGCTGTGCCCGCTGCAAGGGGCCACTGCCCACTGACTGCTGCCATGAGCAGTGTGC
TGCCGGCTGCACGGGCCCCAAGCACTCTGACTGCCTGGCCTGCCTCCACTTCAACCACAGTGGCATCTGTGAGCTGCACT
GCCCAGCCCTGGTCACCTACAACACAGACACGTTTGAGTCCATGCCCAATCCCGAGGGCCGGTATACATTCGGCGCCAGC
TGTGTGACTGCCTGTCCCTACAACTACCTTTCTACGGACGTGGGATCCTGCACCCTCGTCTGCCCCCTGCACAACCAAGA
GGTGACAGCAGAGGATGGAACACAGCGGTGTGAGAAGTGCAGCAAGCCCTGTGCCCGAGTGTGCTATGGTCTGGGCATGG
AGCACTTGCGAGAGGTGAGGGCAGTTACCAGTGCCAATATCCAGGAGTTTGCTGGCTGCAAGAAGATCTTTGGGAGCCTG
GCATTTCTGCCGGAGAGCTTTGATGGGGACCCAGCCTCCAACACTGCCCCGCTCCAGCCAGAGCAGCTCCAAGTGTTTGA
GACTCTGGAAGAGATCACAGGTTACCTATACATCTCAGCATGGCCGGACAGCCTGCCTGACCTCAGCGTCTTCCAGAACC
TGCAAGTAATCCGGGGACGAATTCTGCACAATGGCGCCTACTCGCTGACCCTGCAAGGGCTGGGCATCAGCTGGCTGGGG
CTGCGCTCACTGAGGGAACTGGGCAGTGGACTGGCCCTCATCCACCATAACACCCACCTCTGCTTCGTGCACACGGTGCC
CTGGGACCAGCTCTTTCGGAACCCGCACCAAGCTCTGCTCCACACTGCCAACCGGCCAGAGGACGAGTGTGTGGGCGAGG
GCCTGGCCTGCCACCAGCTGTGCGCCCGAGGGCACTGCTGGGGTCCAGGGCCCACCCAGTGTGTCAACTGCAGCCAGTTC
CTTCGGGGCCAGGAGTGCGTGGAGGAATGCCGAGTACTGCAGGGGCTCCCCAGGGAGTATGTGAATGCCAGGCACTGTTT
GCCGTGCCACCCTGAGTGTCAGCCCCAGAATGGCTCAGTGACCTGTTTTGGACCGGAGGCTGACCAGTGTGTGGCCTGTG
CCCACTATAAGGACCCTCCCTTCTGCGTGGCCCGCTGCCCCAGCGGTGTGAAACCTGACCTCTCCTACATGCCCATCTGG
AAGTTTCCAGATGAGGAGGGCGCATGCCAGCCTTGCCCCATCAACTGCACCCACTCCTGTGTGGACCTGGATGACAAGGG
CTGCCCCGCCGAGCAGAGAGCCAGCCCTCTGACGTCCATCATCTCTGCGGTGGTTGGCATTCTGCTGGTCGTGGTCTTGG
GGGTGGTCTTTGGGATCCTCATCAAGCGACGGCAGCAGAAGATCCGGAAGTACACGATGCGGAGACTGCTGCAGGAAACG
GAGCTGGTGGAGCCGCTGACACCTAGCGGAGCGATGCCCAACCAGGCGCAGATGCGGATCCTGAAAGAGACGGAGCTGAG
GAAGGTGAAGGTGCTTGGATCTGGCGCTTTTGGCACAGTCTACAAGGGCATCTGGATCCCTGATGGGGAGAATGTGAAAA
TTCCAGTGGCCATCAAAGTGTTGAGGGAAAACACATCCCCCAAAGCCAACAAAGAAATCTTAGACGAAGCATACGTGATG
GCTGGTGTGGGCTCCCCATATGTCTCCCGCCTTCTGGGCATCTGCCTGACATCCACGGTGCAGCTGGTGACACAGCTTAT
GCCCTATGGCTGCCTCTTAGACCATGTCCGGGAAAACCGCGGACGCCTGGGCTCCCAGGACCTGCTGAACTGGTGTATGC
AGATTGCCAAGGGGATGAGCTACCTGGAGGATGTGCGGCTCGTACACAGGGACTTGGCCGCTCGGAACGTGCTGGTCAAG
AGTCCCAACCATGTCAAAATTACAGACTTCGGGCTGGCTCGGCTGCTGGACATTGACGAGACAGAGTACCATGCAGATGG
GGGCAAGGTGCCCATCAAGTGGATGGCGCTGGAGTCCATTCTCCGCCGGCGGTTCACCCACCAGAGTGATGTGTGGAGTT
ATGGTGTGACTGTGTGGGAGCTGATGACTTTTGGGGCCAAACCTTACGATGGGATCCCAGCCCGGGAGATCCCTGACCTG
CTGGAAAAGGGGGAGCGGCTGCCCCAGCCCCCCATCTGCACCATTGATGTCTACATGATCATGGTCAAATGTTGGATGAT
TGACTCTGAATGTCGGCCAAGATTCCGGGAGTTGGTGTCTGAATTCTCCCGCATGGCCAGGGACCCCCAGCGCTTTGTGG
TCATCCAGAATGAGGACTTGGGCCCAGCCAGTCCCTTGGACAGCACCTTCTACCGCTCACTGCTGGAGGACGATGACATG
GGGGACCTGGTGGATGCTGAGGAGTATCTGGTACCCCAGCAGGGCTTCTTCTGTCCAGACCCTGCCCCGGGCGCTGGGGG
CATGGTCCACCACAGGCACCGCAGCTCATCTACCAGGAGTGGCGGTGGGGACCTGACACTAGGGCTGGAGCCCTCTGAAG
AGGAGGCCCCCAGGTCTCCACTGGCACCCTCCGAAGGGGCTGGCTCCGATGTATTTGATGGTGACCTGGGAATGGGGGCA
GCCAAGGGGCTGCAAAGCCTCCCCACACATGACCCCAGCCCTCTACAGCGGTACAGTGAGGACCCCACAGTACCCCTGCC
CTCTGAGACTGATGGCTACGTTGCCCCCCTGACCTGCAGCCCCCAGCCTGAATATGTGAACCAGCCAGATGTTCGGCCCC
AGCCCCCTTCGCCCCGAGAGGGCCCTCTGCCTGCTGCCCGACCTGCTGGTGCCACTCTGGAAAGGCCCAAGACTCTCTCC
CCAGGGAAGAATGGGGTCGTCAAAGACGTTTTTGCCTTTGGGGGTGCCGTGGAGAACCCCGAGTACTTGACACCCCAGGG
AGGAGCTGCCCCTCAGCCCCACCCTCCTCCTGCCTTCAGCCCAGCCTTCGACAACCTCTATTACTGGGACCAGGACCCAC
CAGAGCGGGGGGCTCCACCCAGCACCTTCAAAGGGACACCTACGGCAGAGAACCCAGAGTACCTGGGTCTGGACGTGCCA
GTGTGAACCAGAAGGCCAAGTCCGCAGAAGCCCTGATGTGTCCTCAGGGAGCAGGGAAGGCCTGACTTCTGCTGGCATCA
AGAGGTGGGAGGGCCCTCCGACCACTTCCAGGGGAACCTGCCATGCCAGGAACCTGTCCTAAGGAACCTTCCTTCCTGCT
TGAGTTCCCAGATGGCTGGAAGGGGTCCAGCCTCGTTGGAAGAGGAACAGCACTGGGGAGTCTTTGTGGATTCTGAGGCC
CTGCCCAATGAGACTCTAGGGTCCAGTGGATGCCACAGCCCAGCTTGGCCCTTTCCTTCCAGATCCTGGGTACTGAAAGC
CTTAGGGAAGCTGGCCTGAGAGGGGAAGCGGCCCTAAGGGAGTGTCTAAGAACAAAAGCGACCCATTCAGAGACTGTCCC
TGAAACCTAGTACTGCCCCCCATGAGGAAGGAACAGCAATGGTGTCAGTATCCAGGCTTTGTACAGAGTGCTTTTCTGTT
TAGTTTTTACTTTTTTTGTTTTGTTTTTTTAAAGATGAAATAAAGACCCAGGGGGAGAATGGGTGTTGTATGGGGAGGCA
AGTGTGGGGGGTCCTTCTCCACACCCACTTTGTCCATTTGCAAATATATTTTGGAAAACAGCTA
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Primary source |
RefSeq : NM_001005862.1 (GI:54792097)
|
Name |
V-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) (ERBB2), transcript variant 2
|
Type of transcript |
mRNA
|
Organism |
Homo sapiens
|
Length |
4816 nt
|
Map |
17q21.1
|
Location |
Chromosome 17 (NC_000017.10) strand : +
37844392...37844530 | 37844948...37845052 | 37849513...37849577 | 37851240...37851433 |
37863242...37863393 | 37864573...37864786 | 37865570...37865704 | 37866065...37866133 |
37866338...37866453 | 37866592...37866733 | 37868180...37868299 | 37868574...37868700 |
37871538...37871611 | 37871698...37871788 | 37871992...37872191 | 37872553...37872685 |
37872767...37872857 | 37873572...37873732 | 37876039...37876086 | 37879571...37879709 |
37879790...37879912 | 37880164...37880262 | 37880978...37881163 | 37881301...37881456 |
37881579...37881654 | 37881959...37882105 | 37882814...37882911 | 37883067...37883255 |
37883547...37883799 | 37883941...37884914 |
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Exon(s) |
Start |
End |
Length |
is coding |
Exon 1
|
1
|
139
|
139
|
1
|
Exon 2
|
140
|
244
|
105
|
1
|
Exon 3
|
245
|
309
|
65
|
1
|
Exon 4
|
310
|
503
|
194
|
1
|
Exon 6
|
504
|
655
|
152
|
1
|
Exon 7
|
656
|
869
|
214
|
1
|
Exon 8
|
870
|
1004
|
135
|
1
|
Exon 9
|
1005
|
1073
|
69
|
1
|
Exon 10
|
1074
|
1189
|
116
|
1
|
Exon 11
|
1190
|
1331
|
142
|
1
|
Exon 12
|
1332
|
1451
|
120
|
1
|
Exon 13
|
1452
|
1578
|
127
|
1
|
Exon 14
|
1579
|
1652
|
74
|
1
|
Exon 15
|
1653
|
1743
|
91
|
1
|
Exon 16
|
1744
|
1943
|
200
|
1
|
Exon 17
|
1944
|
2076
|
133
|
1
|
Exon 18
|
2077
|
2167
|
91
|
1
|
Exon 19
|
2168
|
2328
|
161
|
1
|
Exon 20
|
2329
|
2376
|
48
|
1
|
Exon 21
|
2377
|
2515
|
139
|
1
|
Exon 22
|
2516
|
2638
|
123
|
1
|
Exon 23
|
2639
|
2737
|
99
|
1
|
Exon 24
|
2738
|
2923
|
186
|
1
|
Exon 25
|
2924
|
3079
|
156
|
1
|
Exon 26
|
3080
|
3155
|
76
|
1
|
Exon 27
|
3156
|
3302
|
147
|
1
|
Exon 28
|
3303
|
3400
|
98
|
1
|
Exon 29
|
3401
|
3589
|
189
|
1
|
Exon 30
|
3590
|
3842
|
253
|
1
|
Exon 31
|
3843
|
4816
|
974
|
1
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Primary source |
NCBI : CCDS45667
|
Nucleotide |
ERBB2, mRNA isoform 2[NM_001005862.1] : 521...4198
|
Length |
3678
|
Location |
Chromosome 17 (NC_000017.10) strand : +
37863259...37863393 | 37864573...37864786 | 37865570...37865704 | 37866065...37866133 |
37866338...37866453 | 37866592...37866733 | 37868180...37868299 | 37868574...37868700 |
37871538...37871611 | 37871698...37871788 | 37871992...37872191 | 37872553...37872685 |
37872767...37872857 | 37873572...37873732 | 37876039...37876086 | 37879571...37879709 |
37879790...37879912 | 37880164...37880262 | 37880978...37881163 | 37881301...37881456 |
37881579...37881654 | 37881959...37882105 | 37882814...37882911 | 37883067...37883255 |
37883547...37883799 | 37883941...37884296 |
|
Start codon |
1
|
Translation |
NP_001005862.1 |
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1 |
GTTCCCGGAT |
TTTTGTGGGC |
GCCTGCCCCG |
CCCCTCGTCC |
CCCTGCTGTG |
TCCATATATC |
GAGGCGATAG |
GGTTAAGGGA |
|
81 |
AGGCGGACGC |
CTGATGGGTT |
AATGAGCAAA |
CTGAAGTGTT |
TTCCATGATC |
TTTTTTGAGT |
CGCAATTGAA |
GTACCACCTC |
|
161 |
CCGAGGGTGA |
TTGCTTCCCC |
ATGCGGGGTA |
GAACCTTTGC |
TGTCCTGTTC |
ACCACTCTAC |
CTCCAGCACA |
GAATTTGGCT |
|
241 |
TATGCCTACT |
CAATGTGAAG |
ATGATGAGGA |
TGAAAACCTT |
TGTGATGATC |
CACTTCCACT |
TAATGAATGG |
TGGCAAAGCA |
|
321 |
AAGCTATATT |
CAAGACCACA |
TGCAAAGCTA |
CTCCCTGAGC |
AAAGAGTCAC |
AGATAAAACG |
GGGGCACCAG |
TAGAATGGCC |
|
401 |
AGGACAAACG |
CAGTGCAGCA |
CAGAGACTCA |
GACCCTGGCA |
GCCATGCCTG |
CGCAGGCAGT |
GATGAGAGTG |
ACATGTACTG |
|
481 |
TTGTGGACAT |
GCACAAAAGT |
GAGTGTGCAC |
CGGCACAGAC |
ATGAAGCTGC |
GGCTCCCTGC |
CAGTCCCGAG |
ACCCACCTGG |
|
561 |
ACATGCTCCG |
CCACCTCTAC |
CAGGGCTGCC |
AGGTGGTGCA |
GGGAAACCTG |
GAACTCACCT |
ACCTGCCCAC |
CAATGCCAGC |
|
641 |
CTGTCCTTCC |
TGCAGGATAT |
CCAGGAGGTG |
CAGGGCTACG |
TGCTCATCGC |
TCACAACCAA |
GTGAGGCAGG |
TCCCACTGCA |
|
721 |
GAGGCTGCGG |
ATTGTGCGAG |
GCACCCAGCT |
CTTTGAGGAC |
AACTATGCCC |
TGGCCGTGCT |
AGACAATGGA |
GACCCGCTGA |
|
801 |
ACAATACCAC |
CCCTGTCACA |
GGGGCCTCCC |
CAGGAGGCCT |
GCGGGAGCTG |
CAGCTTCGAA |
GCCTCACAGA |
GATCTTGAAA |
|
881 |
GGAGGGGTCT |
TGATCCAGCG |
GAACCCCCAG |
CTCTGCTACC |
AGGACACGAT |
TTTGTGGAAG |
GACATCTTCC |
ACAAGAACAA |
|
961 |
CCAGCTGGCT |
CTCACACTGA |
TAGACACCAA |
CCGCTCTCGG |
GCCTGCCACC |
CCTGTTCTCC |
GATGTGTAAG |
GGCTCCCGCT |
|
1041 |
GCTGGGGAGA |
GAGTTCTGAG |
GATTGTCAGA |
GCCTGACGCG |
CACTGTCTGT |
GCCGGTGGCT |
GTGCCCGCTG |
CAAGGGGCCA |
|
1121 |
CTGCCCACTG |
ACTGCTGCCA |
TGAGCAGTGT |
GCTGCCGGCT |
GCACGGGCCC |
CAAGCACTCT |
GACTGCCTGG |
CCTGCCTCCA |
|
1201 |
CTTCAACCAC |
AGTGGCATCT |
GTGAGCTGCA |
CTGCCCAGCC |
CTGGTCACCT |
ACAACACAGA |
CACGTTTGAG |
TCCATGCCCA |
|
1281 |
ATCCCGAGGG |
CCGGTATACA |
TTCGGCGCCA |
GCTGTGTGAC |
TGCCTGTCCC |
TACAACTACC |
TTTCTACGGA |
CGTGGGATCC |
|
1361 |
TGCACCCTCG |
TCTGCCCCCT |
GCACAACCAA |
GAGGTGACAG |
CAGAGGATGG |
AACACAGCGG |
TGTGAGAAGT |
GCAGCAAGCC |
|
1441 |
CTGTGCCCGA |
GTGTGCTATG |
GTCTGGGCAT |
GGAGCACTTG |
CGAGAGGTGA |
GGGCAGTTAC |
CAGTGCCAAT |
ATCCAGGAGT |
|
1521 |
TTGCTGGCTG |
CAAGAAGATC |
TTTGGGAGCC |
TGGCATTTCT |
GCCGGAGAGC |
TTTGATGGGG |
ACCCAGCCTC |
CAACACTGCC |
|
1601 |
CCGCTCCAGC |
CAGAGCAGCT |
CCAAGTGTTT |
GAGACTCTGG |
AAGAGATCAC |
AGGTTACCTA |
TACATCTCAG |
CATGGCCGGA |
|
1681 |
CAGCCTGCCT |
GACCTCAGCG |
TCTTCCAGAA |
CCTGCAAGTA |
ATCCGGGGAC |
GAATTCTGCA |
CAATGGCGCC |
TACTCGCTGA |
|
1761 |
CCCTGCAAGG |
GCTGGGCATC |
AGCTGGCTGG |
GGCTGCGCTC |
ACTGAGGGAA |
CTGGGCAGTG |
GACTGGCCCT |
CATCCACCAT |
|
1841 |
AACACCCACC |
TCTGCTTCGT |
GCACACGGTG |
CCCTGGGACC |
AGCTCTTTCG |
GAACCCGCAC |
CAAGCTCTGC |
TCCACACTGC |
|
1921 |
CAACCGGCCA |
GAGGACGAGT |
GTGTGGGCGA |
GGGCCTGGCC |
TGCCACCAGC |
TGTGCGCCCG |
AGGGCACTGC |
TGGGGTCCAG |
|
2001 |
GGCCCACCCA |
GTGTGTCAAC |
TGCAGCCAGT |
TCCTTCGGGG |
CCAGGAGTGC |
GTGGAGGAAT |
GCCGAGTACT |
GCAGGGGCTC |
|
2081 |
CCCAGGGAGT |
ATGTGAATGC |
CAGGCACTGT |
TTGCCGTGCC |
ACCCTGAGTG |
TCAGCCCCAG |
AATGGCTCAG |
TGACCTGTTT |
|
2161 |
TGGACCGGAG |
GCTGACCAGT |
GTGTGGCCTG |
TGCCCACTAT |
AAGGACCCTC |
CCTTCTGCGT |
GGCCCGCTGC |
CCCAGCGGTG |
|
2241 |
TGAAACCTGA |
CCTCTCCTAC |
ATGCCCATCT |
GGAAGTTTCC |
AGATGAGGAG |
GGCGCATGCC |
AGCCTTGCCC |
CATCAACTGC |
|
2321 |
ACCCACTCCT |
GTGTGGACCT |
GGATGACAAG |
GGCTGCCCCG |
CCGAGCAGAG |
AGCCAGCCCT |
CTGACGTCCA |
TCATCTCTGC |
|
2401 |
GGTGGTTGGC |
ATTCTGCTGG |
TCGTGGTCTT |
GGGGGTGGTC |
TTTGGGATCC |
TCATCAAGCG |
ACGGCAGCAG |
AAGATCCGGA |
|
2481 |
AGTACACGAT |
GCGGAGACTG |
CTGCAGGAAA |
CGGAGCTGGT |
GGAGCCGCTG |
ACACCTAGCG |
GAGCGATGCC |
CAACCAGGCG |
|
2561 |
CAGATGCGGA |
TCCTGAAAGA |
GACGGAGCTG |
AGGAAGGTGA |
AGGTGCTTGG |
ATCTGGCGCT |
TTTGGCACAG |
TCTACAAGGG |
|
2641 |
CATCTGGATC |
CCTGATGGGG |
AGAATGTGAA |
AATTCCAGTG |
GCCATCAAAG |
TGTTGAGGGA |
AAACACATCC |
CCCAAAGCCA |
|
2721 |
ACAAAGAAAT |
CTTAGACGAA |
GCATACGTGA |
TGGCTGGTGT |
GGGCTCCCCA |
TATGTCTCCC |
GCCTTCTGGG |
CATCTGCCTG |
|
2801 |
ACATCCACGG |
TGCAGCTGGT |
GACACAGCTT |
ATGCCCTATG |
GCTGCCTCTT |
AGACCATGTC |
CGGGAAAACC |
GCGGACGCCT |
|
2881 |
GGGCTCCCAG |
GACCTGCTGA |
ACTGGTGTAT |
GCAGATTGCC |
AAGGGGATGA |
GCTACCTGGA |
GGATGTGCGG |
CTCGTACACA |
|
2961 |
GGGACTTGGC |
CGCTCGGAAC |
GTGCTGGTCA |
AGAGTCCCAA |
CCATGTCAAA |
ATTACAGACT |
TCGGGCTGGC |
TCGGCTGCTG |
|
3041 |
GACATTGACG |
AGACAGAGTA |
CCATGCAGAT |
GGGGGCAAGG |
TGCCCATCAA |
GTGGATGGCG |
CTGGAGTCCA |
TTCTCCGCCG |
|
3121 |
GCGGTTCACC |
CACCAGAGTG |
ATGTGTGGAG |
TTATGGTGTG |
ACTGTGTGGG |
AGCTGATGAC |
TTTTGGGGCC |
AAACCTTACG |
|
3201 |
ATGGGATCCC |
AGCCCGGGAG |
ATCCCTGACC |
TGCTGGAAAA |
GGGGGAGCGG |
CTGCCCCAGC |
CCCCCATCTG |
CACCATTGAT |
|
3281 |
GTCTACATGA |
TCATGGTCAA |
ATGTTGGATG |
ATTGACTCTG |
AATGTCGGCC |
AAGATTCCGG |
GAGTTGGTGT |
CTGAATTCTC |
|
3361 |
CCGCATGGCC |
AGGGACCCCC |
AGCGCTTTGT |
GGTCATCCAG |
AATGAGGACT |
TGGGCCCAGC |
CAGTCCCTTG |
GACAGCACCT |
|
3441 |
TCTACCGCTC |
ACTGCTGGAG |
GACGATGACA |
TGGGGGACCT |
GGTGGATGCT |
GAGGAGTATC |
TGGTACCCCA |
GCAGGGCTTC |
|
3521 |
TTCTGTCCAG |
ACCCTGCCCC |
GGGCGCTGGG |
GGCATGGTCC |
ACCACAGGCA |
CCGCAGCTCA |
TCTACCAGGA |
GTGGCGGTGG |
|
3601 |
GGACCTGACA |
CTAGGGCTGG |
AGCCCTCTGA |
AGAGGAGGCC |
CCCAGGTCTC |
CACTGGCACC |
CTCCGAAGGG |
GCTGGCTCCG |
|
3681 |
ATGTATTTGA |
TGGTGACCTG |
GGAATGGGGG |
CAGCCAAGGG |
GCTGCAAAGC |
CTCCCCACAC |
ATGACCCCAG |
CCCTCTACAG |
|
3761 |
CGGTACAGTG |
AGGACCCCAC |
AGTACCCCTG |
CCCTCTGAGA |
CTGATGGCTA |
CGTTGCCCCC |
CTGACCTGCA |
GCCCCCAGCC |
|
3841 |
TGAATATGTG |
AACCAGCCAG |
ATGTTCGGCC |
CCAGCCCCCT |
TCGCCCCGAG |
AGGGCCCTCT |
GCCTGCTGCC |
CGACCTGCTG |
|
3921 |
GTGCCACTCT |
GGAAAGGCCC |
AAGACTCTCT |
CCCCAGGGAA |
GAATGGGGTC |
GTCAAAGACG |
TTTTTGCCTT |
TGGGGGTGCC |
|
4001 |
GTGGAGAACC |
CCGAGTACTT |
GACACCCCAG |
GGAGGAGCTG |
CCCCTCAGCC |
CCACCCTCCT |
CCTGCCTTCA |
GCCCAGCCTT |
|
4081 |
CGACAACCTC |
TATTACTGGG |
ACCAGGACCC |
ACCAGAGCGG |
GGGGCTCCAC |
CCAGCACCTT |
CAAAGGGACA |
CCTACGGCAG |
|
4161 |
AGAACCCAGA |
GTACCTGGGT |
CTGGACGTGC |
CAGTGTGAAC |
CAGAAGGCCA |
AGTCCGCAGA |
AGCCCTGATG |
TGTCCTCAGG |
|
4241 |
GAGCAGGGAA |
GGCCTGACTT |
CTGCTGGCAT |
CAAGAGGTGG |
GAGGGCCCTC |
CGACCACTTC |
CAGGGGAACC |
TGCCATGCCA |
|
4321 |
GGAACCTGTC |
CTAAGGAACC |
TTCCTTCCTG |
CTTGAGTTCC |
CAGATGGCTG |
GAAGGGGTCC |
AGCCTCGTTG |
GAAGAGGAAC |
|
4401 |
AGCACTGGGG |
AGTCTTTGTG |
GATTCTGAGG |
CCCTGCCCAA |
TGAGACTCTA |
GGGTCCAGTG |
GATGCCACAG |
CCCAGCTTGG |
|
4481 |
CCCTTTCCTT |
CCAGATCCTG |
GGTACTGAAA |
GCCTTAGGGA |
AGCTGGCCTG |
AGAGGGGAAG |
CGGCCCTAAG |
GGAGTGTCTA |
|
4561 |
AGAACAAAAG |
CGACCCATTC |
AGAGACTGTC |
CCTGAAACCT |
AGTACTGCCC |
CCCATGAGGA |
AGGAACAGCA |
ATGGTGTCAG |
|
4641 |
TATCCAGGCT |
TTGTACAGAG |
TGCTTTTCTG |
TTTAGTTTTT |
ACTTTTTTTG |
TTTTGTTTTT |
TTAAAGATGA |
AATAAAGACC |
|
4721 |
CAGGGGGAGA |
ATGGGTGTTG |
TATGGGGAGG |
CAAGTGTGGG |
GGGTCCTTCT |
CCACACCCAC |
TTTGTCCATT |
TGCAAATATA |
|
4801 |
TTTTGGAAAA |
CAGCTA |
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>gi|54792097|ref|NM_001005862.1|V-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) (ERBB2), transcript variant 2
GTTCCCGGATTTTTGTGGGCGCCTGCCCCGCCCCTCGTCCCCCTGCTGTGTCCATATATCGAGGCGATAGGGTTAAGGGA
AGGCGGACGCCTGATGGGTTAATGAGCAAACTGAAGTGTTTTCCATGATCTTTTTTGAGTCGCAATTGAAGTACCACCTC
CCGAGGGTGATTGCTTCCCCATGCGGGGTAGAACCTTTGCTGTCCTGTTCACCACTCTACCTCCAGCACAGAATTTGGCT
TATGCCTACTCAATGTGAAGATGATGAGGATGAAAACCTTTGTGATGATCCACTTCCACTTAATGAATGGTGGCAAAGCA
AAGCTATATTCAAGACCACATGCAAAGCTACTCCCTGAGCAAAGAGTCACAGATAAAACGGGGGCACCAGTAGAATGGCC
AGGACAAACGCAGTGCAGCACAGAGACTCAGACCCTGGCAGCCATGCCTGCGCAGGCAGTGATGAGAGTGACATGTACTG
TTGTGGACATGCACAAAAGTGAGTGTGCACCGGCACAGACATGAAGCTGCGGCTCCCTGCCAGTCCCGAGACCCACCTGG
ACATGCTCCGCCACCTCTACCAGGGCTGCCAGGTGGTGCAGGGAAACCTGGAACTCACCTACCTGCCCACCAATGCCAGC
CTGTCCTTCCTGCAGGATATCCAGGAGGTGCAGGGCTACGTGCTCATCGCTCACAACCAAGTGAGGCAGGTCCCACTGCA
GAGGCTGCGGATTGTGCGAGGCACCCAGCTCTTTGAGGACAACTATGCCCTGGCCGTGCTAGACAATGGAGACCCGCTGA
ACAATACCACCCCTGTCACAGGGGCCTCCCCAGGAGGCCTGCGGGAGCTGCAGCTTCGAAGCCTCACAGAGATCTTGAAA
GGAGGGGTCTTGATCCAGCGGAACCCCCAGCTCTGCTACCAGGACACGATTTTGTGGAAGGACATCTTCCACAAGAACAA
CCAGCTGGCTCTCACACTGATAGACACCAACCGCTCTCGGGCCTGCCACCCCTGTTCTCCGATGTGTAAGGGCTCCCGCT
GCTGGGGAGAGAGTTCTGAGGATTGTCAGAGCCTGACGCGCACTGTCTGTGCCGGTGGCTGTGCCCGCTGCAAGGGGCCA
CTGCCCACTGACTGCTGCCATGAGCAGTGTGCTGCCGGCTGCACGGGCCCCAAGCACTCTGACTGCCTGGCCTGCCTCCA
CTTCAACCACAGTGGCATCTGTGAGCTGCACTGCCCAGCCCTGGTCACCTACAACACAGACACGTTTGAGTCCATGCCCA
ATCCCGAGGGCCGGTATACATTCGGCGCCAGCTGTGTGACTGCCTGTCCCTACAACTACCTTTCTACGGACGTGGGATCC
TGCACCCTCGTCTGCCCCCTGCACAACCAAGAGGTGACAGCAGAGGATGGAACACAGCGGTGTGAGAAGTGCAGCAAGCC
CTGTGCCCGAGTGTGCTATGGTCTGGGCATGGAGCACTTGCGAGAGGTGAGGGCAGTTACCAGTGCCAATATCCAGGAGT
TTGCTGGCTGCAAGAAGATCTTTGGGAGCCTGGCATTTCTGCCGGAGAGCTTTGATGGGGACCCAGCCTCCAACACTGCC
CCGCTCCAGCCAGAGCAGCTCCAAGTGTTTGAGACTCTGGAAGAGATCACAGGTTACCTATACATCTCAGCATGGCCGGA
CAGCCTGCCTGACCTCAGCGTCTTCCAGAACCTGCAAGTAATCCGGGGACGAATTCTGCACAATGGCGCCTACTCGCTGA
CCCTGCAAGGGCTGGGCATCAGCTGGCTGGGGCTGCGCTCACTGAGGGAACTGGGCAGTGGACTGGCCCTCATCCACCAT
AACACCCACCTCTGCTTCGTGCACACGGTGCCCTGGGACCAGCTCTTTCGGAACCCGCACCAAGCTCTGCTCCACACTGC
CAACCGGCCAGAGGACGAGTGTGTGGGCGAGGGCCTGGCCTGCCACCAGCTGTGCGCCCGAGGGCACTGCTGGGGTCCAG
GGCCCACCCAGTGTGTCAACTGCAGCCAGTTCCTTCGGGGCCAGGAGTGCGTGGAGGAATGCCGAGTACTGCAGGGGCTC
CCCAGGGAGTATGTGAATGCCAGGCACTGTTTGCCGTGCCACCCTGAGTGTCAGCCCCAGAATGGCTCAGTGACCTGTTT
TGGACCGGAGGCTGACCAGTGTGTGGCCTGTGCCCACTATAAGGACCCTCCCTTCTGCGTGGCCCGCTGCCCCAGCGGTG
TGAAACCTGACCTCTCCTACATGCCCATCTGGAAGTTTCCAGATGAGGAGGGCGCATGCCAGCCTTGCCCCATCAACTGC
ACCCACTCCTGTGTGGACCTGGATGACAAGGGCTGCCCCGCCGAGCAGAGAGCCAGCCCTCTGACGTCCATCATCTCTGC
GGTGGTTGGCATTCTGCTGGTCGTGGTCTTGGGGGTGGTCTTTGGGATCCTCATCAAGCGACGGCAGCAGAAGATCCGGA
AGTACACGATGCGGAGACTGCTGCAGGAAACGGAGCTGGTGGAGCCGCTGACACCTAGCGGAGCGATGCCCAACCAGGCG
CAGATGCGGATCCTGAAAGAGACGGAGCTGAGGAAGGTGAAGGTGCTTGGATCTGGCGCTTTTGGCACAGTCTACAAGGG
CATCTGGATCCCTGATGGGGAGAATGTGAAAATTCCAGTGGCCATCAAAGTGTTGAGGGAAAACACATCCCCCAAAGCCA
ACAAAGAAATCTTAGACGAAGCATACGTGATGGCTGGTGTGGGCTCCCCATATGTCTCCCGCCTTCTGGGCATCTGCCTG
ACATCCACGGTGCAGCTGGTGACACAGCTTATGCCCTATGGCTGCCTCTTAGACCATGTCCGGGAAAACCGCGGACGCCT
GGGCTCCCAGGACCTGCTGAACTGGTGTATGCAGATTGCCAAGGGGATGAGCTACCTGGAGGATGTGCGGCTCGTACACA
GGGACTTGGCCGCTCGGAACGTGCTGGTCAAGAGTCCCAACCATGTCAAAATTACAGACTTCGGGCTGGCTCGGCTGCTG
GACATTGACGAGACAGAGTACCATGCAGATGGGGGCAAGGTGCCCATCAAGTGGATGGCGCTGGAGTCCATTCTCCGCCG
GCGGTTCACCCACCAGAGTGATGTGTGGAGTTATGGTGTGACTGTGTGGGAGCTGATGACTTTTGGGGCCAAACCTTACG
ATGGGATCCCAGCCCGGGAGATCCCTGACCTGCTGGAAAAGGGGGAGCGGCTGCCCCAGCCCCCCATCTGCACCATTGAT
GTCTACATGATCATGGTCAAATGTTGGATGATTGACTCTGAATGTCGGCCAAGATTCCGGGAGTTGGTGTCTGAATTCTC
CCGCATGGCCAGGGACCCCCAGCGCTTTGTGGTCATCCAGAATGAGGACTTGGGCCCAGCCAGTCCCTTGGACAGCACCT
TCTACCGCTCACTGCTGGAGGACGATGACATGGGGGACCTGGTGGATGCTGAGGAGTATCTGGTACCCCAGCAGGGCTTC
TTCTGTCCAGACCCTGCCCCGGGCGCTGGGGGCATGGTCCACCACAGGCACCGCAGCTCATCTACCAGGAGTGGCGGTGG
GGACCTGACACTAGGGCTGGAGCCCTCTGAAGAGGAGGCCCCCAGGTCTCCACTGGCACCCTCCGAAGGGGCTGGCTCCG
ATGTATTTGATGGTGACCTGGGAATGGGGGCAGCCAAGGGGCTGCAAAGCCTCCCCACACATGACCCCAGCCCTCTACAG
CGGTACAGTGAGGACCCCACAGTACCCCTGCCCTCTGAGACTGATGGCTACGTTGCCCCCCTGACCTGCAGCCCCCAGCC
TGAATATGTGAACCAGCCAGATGTTCGGCCCCAGCCCCCTTCGCCCCGAGAGGGCCCTCTGCCTGCTGCCCGACCTGCTG
GTGCCACTCTGGAAAGGCCCAAGACTCTCTCCCCAGGGAAGAATGGGGTCGTCAAAGACGTTTTTGCCTTTGGGGGTGCC
GTGGAGAACCCCGAGTACTTGACACCCCAGGGAGGAGCTGCCCCTCAGCCCCACCCTCCTCCTGCCTTCAGCCCAGCCTT
CGACAACCTCTATTACTGGGACCAGGACCCACCAGAGCGGGGGGCTCCACCCAGCACCTTCAAAGGGACACCTACGGCAG
AGAACCCAGAGTACCTGGGTCTGGACGTGCCAGTGTGAACCAGAAGGCCAAGTCCGCAGAAGCCCTGATGTGTCCTCAGG
GAGCAGGGAAGGCCTGACTTCTGCTGGCATCAAGAGGTGGGAGGGCCCTCCGACCACTTCCAGGGGAACCTGCCATGCCA
GGAACCTGTCCTAAGGAACCTTCCTTCCTGCTTGAGTTCCCAGATGGCTGGAAGGGGTCCAGCCTCGTTGGAAGAGGAAC
AGCACTGGGGAGTCTTTGTGGATTCTGAGGCCCTGCCCAATGAGACTCTAGGGTCCAGTGGATGCCACAGCCCAGCTTGG
CCCTTTCCTTCCAGATCCTGGGTACTGAAAGCCTTAGGGAAGCTGGCCTGAGAGGGGAAGCGGCCCTAAGGGAGTGTCTA
AGAACAAAAGCGACCCATTCAGAGACTGTCCCTGAAACCTAGTACTGCCCCCCATGAGGAAGGAACAGCAATGGTGTCAG
TATCCAGGCTTTGTACAGAGTGCTTTTCTGTTTAGTTTTTACTTTTTTTGTTTTGTTTTTTTAAAGATGAAATAAAGACC
CAGGGGGAGAATGGGTGTTGTATGGGGAGGCAAGTGTGGGGGGTCCTTCTCCACACCCACTTTGTCCATTTGCAAATATA
TTTTGGAAAACAGCTA
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Exon number |
1
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Length |
139 nt
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Location |
Chromosome 17 (NC_000017.10) : 37844392...37844530 (+)
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Is part of |
ERBB2, mRNA isoform 2
(NM_001005862.1)
|
Sequence |
Show
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GTTCCCGGATTTTTGTGGGCGCCTGCCCCGCCCCTCGTCCCCCTGCTGTGTCCATATATCGAGGCGATAGGGTTAAGGGA
AGGCGGACGCCTGATGGGTTAATGAGCAAACTGAAGTGTTTTCCATGATCTTTTTTGAG
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Exon number |
2
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Length |
105 nt
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Location |
Chromosome 17 (NC_000017.10) : 37844948...37845052 (+)
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Is part of |
ERBB2, mRNA isoform 2
(NM_001005862.1)
|
Sequence |
Show
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TCGCAATTGAAGTACCACCTCCCGAGGGTGATTGCTTCCCCATGCGGGGTAGAACCTTTGCTGTCCTGTTCACCACTCTA
CCTCCAGCACAGAATTTGGCTTATG
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Exon number |
4
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Length |
194 nt
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Location |
Chromosome 17 (NC_000017.10) : 37851240...37851433 (+)
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Is part of |
ERBB2, mRNA isoform 2
(NM_001005862.1)
|
Sequence |
Show
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GTGGCAAAGCAAAGCTATATTCAAGACCACATGCAAAGCTACTCCCTGAGCAAAGAGTCACAGATAAAACGGGGGCACCA
GTAGAATGGCCAGGACAAACGCAGTGCAGCACAGAGACTCAGACCCTGGCAGCCATGCCTGCGCAGGCAGTGATGAGAGT
GACATGTACTGTTGTGGACATGCACAAAAGTGAG
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Exon number |
5
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Length |
311 nt
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Location |
Chromosome 17 (NC_000017.10) : 37856253...37856563 (+)
|
Is part of |
ERBB2, mRNA isoform 1
(NM_004448.2)
|
Sequence |
Show
|
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GGAGGAGGTGGAGGAGGAGGGCTGCTTGAGGAAGTATAAGAATGAAGTTGTGAAGCTGAGATTCCCCTCCATTGGGACCG
GAGAAACCAGGGGAGCCCCCCGGGCAGCCGCGCGCCCCTTCCCACGGGGCCCTTTACTGCGCCGCGCGCCCGGCCCCCAC
CCCTCGCAGCACCCCGCGCCCCGCGCCCTCCCAGCCGGGTCCAGCCGGAGCCATGGGGCCGGAGCCGCAGTGAGCACCAT
GGAGCTGGCGGCCTTGTGCCGCTGGGGGCTCCTCCTCGCCCTCTTGCCCCCCGGAGCCGCGAGCACCCAAG
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Exon number |
30
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Length |
253 nt
|
Location |
Chromosome 17 (NC_000017.10) : 37883547...37883799 (+)
|
Is part of |
ERBB2, mRNA isoform 2
(NM_001005862.1)
ERBB2, mRNA isoform 1
(NM_004448.2)
|
Sequence |
Show
|
|
AGTGGCGGTGGGGACCTGACACTAGGGCTGGAGCCCTCTGAAGAGGAGGCCCCCAGGTCTCCACTGGCACCCTCCGAAGG
GGCTGGCTCCGATGTATTTGATGGTGACCTGGGAATGGGGGCAGCCAAGGGGCTGCAAAGCCTCCCCACACATGACCCCA
GCCCTCTACAGCGGTACAGTGAGGACCCCACAGTACCCCTGCCCTCTGAGACTGATGGCTACGTTGCCCCCCTGACCTGC
AGCCCCCAGCCTG
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Exon number |
31
|
Length |
974 nt
|
Location |
Chromosome 17 (NC_000017.10) : 37883941...37884914 (+)
|
Is part of |
ERBB2, mRNA isoform 2
(NM_001005862.1)
ERBB2, mRNA isoform 1
(NM_004448.2)
|
Sequence |
Show
|
|
AATATGTGAACCAGCCAGATGTTCGGCCCCAGCCCCCTTCGCCCCGAGAGGGCCCTCTGCCTGCTGCCCGACCTGCTGGT
GCCACTCTGGAAAGGCCCAAGACTCTCTCCCCAGGGAAGAATGGGGTCGTCAAAGACGTTTTTGCCTTTGGGGGTGCCGT
GGAGAACCCCGAGTACTTGACACCCCAGGGAGGAGCTGCCCCTCAGCCCCACCCTCCTCCTGCCTTCAGCCCAGCCTTCG
ACAACCTCTATTACTGGGACCAGGACCCACCAGAGCGGGGGGCTCCACCCAGCACCTTCAAAGGGACACCTACGGCAGAG
AACCCAGAGTACCTGGGTCTGGACGTGCCAGTGTGAACCAGAAGGCCAAGTCCGCAGAAGCCCTGATGTGTCCTCAGGGA
GCAGGGAAGGCCTGACTTCTGCTGGCATCAAGAGGTGGGAGGGCCCTCCGACCACTTCCAGGGGAACCTGCCATGCCAGG
AACCTGTCCTAAGGAACCTTCCTTCCTGCTTGAGTTCCCAGATGGCTGGAAGGGGTCCAGCCTCGTTGGAAGAGGAACAG
CACTGGGGAGTCTTTGTGGATTCTGAGGCCCTGCCCAATGAGACTCTAGGGTCCAGTGGATGCCACAGCCCAGCTTGGCC
CTTTCCTTCCAGATCCTGGGTACTGAAAGCCTTAGGGAAGCTGGCCTGAGAGGGGAAGCGGCCCTAAGGGAGTGTCTAAG
AACAAAAGCGACCCATTCAGAGACTGTCCCTGAAACCTAGTACTGCCCCCCATGAGGAAGGAACAGCAATGGTGTCAGTA
TCCAGGCTTTGTACAGAGTGCTTTTCTGTTTAGTTTTTACTTTTTTTGTTTTGTTTTTTTAAAGATGAAATAAAGACCCA
GGGGGAGAATGGGTGTTGTATGGGGAGGCAAGTGTGGGGGGTCCTTCTCCACACCCACTTTGTCCATTTGCAAATATATT
TTGGAAAACAGCTA
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Primary source |
Uniprot : P04626
|
Name |
Receptor tyrosine-protein kinase erbB-2
|
Alternative name(s) |
Metastatic lymph node gene 19 protein Proto-oncogene Neu Proto-oncogene c-ErbB-2 Tyrosine kinase-type cell surface receptor HER2 p185erbB2
|
Synonym(s) |
MLN 19
|
Organism |
Homo sapiens
|
Length |
1255 aa
|
Protein existence |
---
|
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General annotation (Comments)
|
top
|
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Catalytic activity
|
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
|
Disease
|
Defects in ERBB2 are associated with gastric cancer [MIM:137215]; also known as hereditary familial diffuse gastric cancer (HDGC).
Defects in ERBB2 are involved in the development of glioma (GLM) [MIM:137800]. Gliomas are central nervous system neoplasms derived from glial cells and comprise astrocytomas, glioblastoma multiforme, oligodendrogliomas, and ependymomas.
Defects in ERBB2 are associated with ovarian cancer [MIM:167000]. Ovarian cancer is the leading cause of death from gynecologic malignancy. It is characterized by advanced presentation with loco-regional dissemination in the peritoneal cavity and the rare incidence of visceral metastases. These typical features relate to the biology of the disease, which is a principal determinant of outcome.
Defects in ERBB2 are associated with lung cancer [MIM:211980]; also called adenocarcinoma of lung.
|
Enzyme regulation
|
Not activated by EGF, TGF-alpha and amphiregulin.
|
Function
|
Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Binds to the 5'-TCAAATTC-3' sequence in the MT-CO2 promoter and activates its transcription.
|
Polymorphism
|
There are fours alleles due to the variations in positions 654 and 655. Allele B1 (Ile-654/Ile-655) has a frequency of 0.782; allele B2 (Ile-654/Val-655) has a frequency of 0.206; allele B3 (Val-654/Val-655) has a frequency of 0.012.
|
Ptm
|
Ligand-binding increases phosphorylation on tyrosine residues (By similarity).
|
Similarity
|
Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
Contains 1 protein kinase domain.
|
Subcellular location
|
Isoform 1: Cell membrane; Single-pass type I membrane protein. Cytoplasm, perinuclear region. Nucleus.
Isoform 2: Cytoplasm. Nucleus.
Isoform 3: Cytoplasm. Nucleus.
|
Subunit
|
Heterodimer with each of the other ERBB receptors (Potential). Interacts with PRKCABP and PLXNB1. Part of a complex with EGFR and either PIK3C2A or PIK3C2B. May interact with PIK3C2B when phosphorylated on Tyr-1196. Interacts with MEMO when phosphorylated on Tyr-1248. Interacts with MUC1. Stimulation by heregulin (HRG) in breast cancer cell lines induces binding of MUC1 with gamma-catenin.
|
Tissue specificity
|
Expressed in a variety of tumor tissues including primary breast tumors and tumors from small bowel, esophagus, kidney and mouth.
|
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Biological process
|
transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]
heart development [GO:0007507]
cell proliferation [GO:0008283]
phosphoinositide 3-kinase cascade [GO:0014065]
wound healing [GO:0042060]
positive regulation of MAP kinase activity [GO:0043406]
regulation of angiogenesis [GO:0045765]
positive regulation of cell adhesion [GO:0045785]
protein amino acid autophosphorylation [GO:0046777]
phosphoinositide-mediated signaling [GO:0048015]
positive regulation of epithelial cell proliferation [GO:0050679]
|
Cellular component
|
integral to membrane [GO:0016021]
receptor complex [GO:0043235]
|
Molecular function
|
receptor signaling protein tyrosine kinase activity [GO:0004716]
epidermal growth factor receptor activity [GO:0005006]
ATP binding [GO:0005524]
protein C-terminus binding [GO:0008022]
protein phosphatase binding [GO:0019903]
identical protein binding [GO:0042802]
ErbB-3 class receptor binding [GO:0043125]
protein heterodimerization activity [GO:0046982]
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With
|
Uniprot accession
|
IntAct
|
PTPRK
|
Q15262
|
EBI-641062,EBI-474052
|
SHC1
|
P29353
|
EBI-641062,EBI-78835
|
PTPRC
|
P08575
|
EBI-641062,EBI-1341
|
PIK3C2B
|
O00750
|
EBI-641062,EBI-641107
|
CALM (xeno)
|
P62157
|
EBI-641062,EBI-397403
|
ERBB3
|
P21860
|
EBI-641062,EBI-720706
|
ERBB4
|
Q15303
|
EBI-641062,EBI-80371
|
Calm1 (xeno)
|
P62161
|
EBI-641062,EBI-397530
|
PIK3C2A
|
O00443
|
EBI-641062,EBI-641094
|
PTPRJ
|
Q12913
|
EBI-641062,EBI-2264500
|
PTPRG
|
P23470
|
EBI-641062,
|
7
|
Q02297-7
|
EBI-641062,EBI-2460927
|
EGFR
|
P00533
|
EBI-641062,EBI-297353
|
PTPRO
|
Q16827
|
EBI-641062,EBI-723739
|
PTPN3
|
P26045
|
EBI-641062,
|
ERBB2
|
P04626
|
EBI-641062,EBI-641062
|
PTPN12
|
Q05209
|
EBI-641062,EBI-2266035
|
PTPRB
|
P23467
|
EBI-641062,EBI-1265766
|
PTPRZ1
|
P23471
|
EBI-641062,EBI-2263175
|
PIK3R1
|
P27986
|
EBI-641062,EBI-79464
|
PTPN22
|
Q9Y2R2
|
EBI-641062,
|
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Alternative product(s)
|
top
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  |
Uniprot Identifier
|
Difference(s) with the 'canonical' sequence
|
Notes
|
Sequences
|
Isoform 1
|
P04626-1
|
---
|
'Canonical' sequence
|
Get Fasta
|
Isoform 2
|
P04626-2
|
1-610 : Missing
|
---
|
Get Fasta
|
Isoform 3
|
P04626-3
|
1-686 : Missing
|
---
|
Get Fasta
|
Isoform 4
|
P04626-4
|
1-23 : MELAALCRWGLLLALLPPGAAST -> MPRGSWKP
|
---
|
Get Fasta
|
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|
Feature key |
Position
|
Length
|
Description
|
Feature identifier
|
Molecule processing |
|
|
|
|
Signal
|
1 - 22
|
22
|
Potential
|
P04626-SIGNAL-1
|
Region |
|
|
|
|
Domain
|
720 - 987
|
268
|
Protein kinase
|
P04626-DOMAIN-720
|
Nucleotide binding
|
726 - 734
|
9
|
ATP (By similarity)
|
P04626-NP_BIND-726
|
Region
|
1195 - 1197
|
3
|
Interaction with PIK3C2B (Probable)
|
P04626-REGION-1195
|
Topological domain
|
23 - 652
|
630
|
Extracellular (Potential)
|
P04626-TOPO_DOM-23
|
Topological domain
|
676 - 1255
|
580
|
Cytoplasmic (Potential)
|
P04626-TOPO_DOM-676
|
Transmembrane
|
653 - 675
|
23
|
Helical; (Potential)
|
P04626-TRANSMEM-653
|
Sites |
|
|
|
|
Active site
|
845 - 845
|
1
|
Proton acceptor (By similarity)
|
P04626-ACT_SITE-845
|
Binding site
|
753 - 753
|
1
|
ATP (By similarity)
|
P04626-BINDING-753
|
Natural variations |
|
|
|
|
Natural variant site
|
452 - 452
|
1
|
W -> C (in dbSNP:rs4252633)
|
VAR_016317
|
Natural variant site
|
654 - 654
|
1
|
I -> V (in allele B3; dbSNP:rs1801201)
|
VAR_004077
|
Natural variant site
|
655 - 655
|
1
|
I -> V (in allele B2 and allele B3; dbSNP:rs1136201)
|
VAR_004078
|
Natural variant site
|
755 - 755
|
1
|
L -> P (in adenocarcinoma of lung; somatic mutation)
|
VAR_055432
|
Natural variant site
|
768 - 768
|
1
|
L -> S (in dbSNP:rs56366519)
|
VAR_042097
|
Natural variant site
|
774 - 774
|
1
|
M -> MAYVM (in adenocarcinoma of lung; somatic mutationa)
|
VAR_055433
|
Natural variant site
|
776 - 776
|
1
|
G -> S (in a gastric adenocarcinoma sample; somatic mutation; dbSNP:rs28933369)
|
VAR_042098
|
Natural variant site
|
779 - 779
|
1
|
S -> SVGS (in adenocarcinoma of lung; somatic mutation)
|
VAR_055434
|
Natural variant site
|
857 - 857
|
1
|
N -> S (in ovarian cancer; somatic mutation; dbSNP:rs28933370)
|
VAR_042099
|
Natural variant site
|
914 - 914
|
1
|
E -> K (in glioblastoma; somatic mutation; dbSNP:rs28933368)
|
VAR_055435
|
Natural variant site
|
1170 - 1170
|
1
|
P -> A (in dbSNP:rs1058808 and dbSNP:rs61552325)
|
VAR_016318
|
Natural variant site
|
1216 - 1216
|
1
|
A -> D (in dbSNP:rs55943169)
|
VAR_042100
|
Alternative sequence
|
1 - 23
|
23
|
MELAALCRWGLLLALLPPGAAST -> MPRGSWKP
|
VSP_039248
|
Alternative sequence
|
1 - 610
|
610
|
Missing
|
VSP_039249
|
Alternative sequence
|
1 - 686
|
686
|
Missing
|
VSP_039250
|
Amino acid modifications |
|
|
|
|
Disulfide bond
|
195 - 204
|
10
|
By similarity
|
P04626-DISULFID-195
|
Disulfide bond
|
199 - 212
|
14
|
By similarity
|
P04626-DISULFID-199
|
Disulfide bond
|
220 - 227
|
8
|
By similarity
|
P04626-DISULFID-220
|
Disulfide bond
|
224 - 235
|
12
|
By similarity
|
P04626-DISULFID-224
|
Disulfide bond
|
236 - 244
|
9
|
By similarity
|
P04626-DISULFID-236
|
Disulfide bond
|
240 - 252
|
13
|
By similarity
|
P04626-DISULFID-240
|
Disulfide bond
|
255 - 264
|
10
|
By similarity
|
P04626-DISULFID-255
|
Disulfide bond
|
268 - 295
|
28
|
By similarity
|
P04626-DISULFID-268
|
Disulfide bond
|
299 - 311
|
13
|
By similarity
|
P04626-DISULFID-299
|
Disulfide bond
|
315 - 331
|
17
|
By similarity
|
P04626-DISULFID-315
|
Disulfide bond
|
334 - 338
|
5
|
By similarity
|
P04626-DISULFID-334
|
Disulfide bond
|
511 - 520
|
10
|
By similarity
|
P04626-DISULFID-511
|
Disulfide bond
|
515 - 528
|
14
|
By similarity
|
P04626-DISULFID-515
|
Disulfide bond
|
531 - 540
|
10
|
By similarity
|
P04626-DISULFID-531
|
Disulfide bond
|
544 - 560
|
17
|
By similarity
|
P04626-DISULFID-544
|
Disulfide bond
|
563 - 576
|
14
|
By similarity
|
P04626-DISULFID-563
|
Disulfide bond
|
567 - 584
|
18
|
By similarity
|
P04626-DISULFID-567
|
Disulfide bond
|
587 - 596
|
10
|
By similarity
|
P04626-DISULFID-587
|
Disulfide bond
|
600 - 623
|
24
|
By similarity
|
P04626-DISULFID-600
|
Disulfide bond
|
626 - 634
|
9
|
By similarity
|
P04626-DISULFID-626
|
Disulfide bond
|
630 - 642
|
13
|
By similarity
|
P04626-DISULFID-630
|
Glycosylation
|
68 - 68
|
1
|
N-linked (GlcNAc...) (Potential)
|
P04626-CARBOHYD-68
|
Glycosylation
|
124 - 124
|
1
|
N-linked (GlcNAc...) (Potential)
|
P04626-CARBOHYD-124
|
Glycosylation
|
187 - 187
|
1
|
N-linked (GlcNAc...) (Potential)
|
P04626-CARBOHYD-187
|
Glycosylation
|
259 - 259
|
1
|
N-linked (GlcNAc...) (Potential)
|
P04626-CARBOHYD-259
|
Glycosylation
|
530 - 530
|
1
|
N-linked (GlcNAc...) (Potential)
|
P04626-CARBOHYD-530
|
Glycosylation
|
571 - 571
|
1
|
N-linked (GlcNAc...) (Potential)
|
P04626-CARBOHYD-571
|
Glycosylation
|
629 - 629
|
1
|
N-linked (GlcNAc...) (Potential)
|
P04626-CARBOHYD-629
|
Modified residue
|
735 - 735
|
1
|
Phosphotyrosine
|
P04626-MOD_RES-735
|
Modified residue
|
1054 - 1054
|
1
|
Phosphoserine
|
P04626-MOD_RES-1054
|
Modified residue
|
1139 - 1139
|
1
|
Phosphotyrosine; by autocatalysis (By similarity)
|
P04626-MOD_RES-1139
|
Modified residue
|
1196 - 1196
|
1
|
Phosphotyrosine (Potential)
|
P04626-MOD_RES-1196
|
Modified residue
|
1248 - 1248
|
1
|
Phosphotyrosine; by autocatalysis (By similarity)
|
P04626-MOD_RES-1248
|
Experimental info |
|
|
|
|
Mutagenesis
|
611 - 611
|
1
|
M->A: Prevents synthesis of isoform 2
|
P04626-MUTAGEN-611
|
Mutagenesis
|
687 - 687
|
1
|
M->A: Prevents synthesis of isoform 3
|
P04626-MUTAGEN-687
|
Mutagenesis
|
706 - 706
|
1
|
M->A: No effect on isoform production
|
P04626-MUTAGEN-706
|
Mutagenesis
|
712 - 712
|
1
|
M->A: No effect on isoform production
|
P04626-MUTAGEN-712
|
|
|
|
|
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|
|
1 |
MELAALCRWG |
LLLALLPPGA |
ASTQVCTGTD |
MKLRLPASPE |
THLDMLRHLY |
QGCQVVQGNL |
ELTYLPTNAS |
LSFLQDIQEV |
|
81 |
QGYVLIAHNQ |
VRQVPLQRLR |
IVRGTQLFED |
NYALAVLDNG |
DPLNNTTPVT |
GASPGGLREL |
QLRSLTEILK |
GGVLIQRNPQ |
|
161 |
LCYQDTILWK |
DIFHKNNQLA |
LTLIDTNRSR |
ACHPCSPMCK |
GSRCWGESSE |
DCQSLTRTVC |
AGGCARCKGP |
LPTDCCHEQC |
|
241 |
AAGCTGPKHS |
DCLACLHFNH |
SGICELHCPA |
LVTYNTDTFE |
SMPNPEGRYT |
FGASCVTACP |
YNYLSTDVGS |
CTLVCPLHNQ |
|
321 |
EVTAEDGTQR |
CEKCSKPCAR |
VCYGLGMEHL |
REVRAVTSAN |
IQEFAGCKKI |
FGSLAFLPES |
FDGDPASNTA |
PLQPEQLQVF |
|
401 |
ETLEEITGYL |
YISAWPDSLP |
DLSVFQNLQV |
IRGRILHNGA |
YSLTLQGLGI |
SWLGLRSLRE |
LGSGLALIHH |
NTHLCFVHTV |
|
481 |
PWDQLFRNPH |
QALLHTANRP |
EDECVGEGLA |
CHQLCARGHC |
WGPGPTQCVN |
CSQFLRGQEC |
VEECRVLQGL |
PREYVNARHC |
|
561 |
LPCHPECQPQ |
NGSVTCFGPE |
ADQCVACAHY |
KDPPFCVARC |
PSGVKPDLSY |
MPIWKFPDEE |
GACQPCPINC |
THSCVDLDDK |
|
641 |
GCPAEQRASP |
LTSIISAVVG |
ILLVVVLGVV |
FGILIKRRQQ |
KIRKYTMRRL |
LQETELVEPL |
TPSGAMPNQA |
QMRILKETEL |
|
721 |
RKVKVLGSGA |
FGTVYKGIWI |
PDGENVKIPV |
AIKVLRENTS |
PKANKEILDE |
AYVMAGVGSP |
YVSRLLGICL |
TSTVQLVTQL |
|
801 |
MPYGCLLDHV |
RENRGRLGSQ |
DLLNWCMQIA |
KGMSYLEDVR |
LVHRDLAARN |
VLVKSPNHVK |
ITDFGLARLL |
DIDETEYHAD |
|
881 |
GGKVPIKWMA |
LESILRRRFT |
HQSDVWSYGV |
TVWELMTFGA |
KPYDGIPARE |
IPDLLEKGER |
LPQPPICTID |
VYMIMVKCWM |
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961 |
IDSECRPRFR |
ELVSEFSRMA |
RDPQRFVVIQ |
NEDLGPASPL |
DSTFYRSLLE |
DDDMGDLVDA |
EEYLVPQQGF |
FCPDPAPGAG |
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1041 |
GMVHHRHRSS |
STRSGGGDLT |
LGLEPSEEEA |
PRSPLAPSEG |
AGSDVFDGDL |
GMGAAKGLQS |
LPTHDPSPLQ |
RYSEDPTVPL |
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1121 |
PSETDGYVAP |
LTCSPQPEYV |
NQPDVRPQPP |
SPREGPLPAA |
RPAGATLERP |
KTLSPGKNGV |
VKDVFAFGGA |
VENPEYLTPQ |
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1201 |
GGAAPQPHPP |
PAFSPAFDNL |
YYWDQDPPER |
GAPPSTFKGT |
PTAENPEYLG |
LDVPV |
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>sp|P04626|ERBB2_human Receptor tyrosine-protein kinase erbB-2
MELAALCRWGLLLALLPPGAASTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLPTNASLSFLQDIQEV
QGYVLIAHNQVRQVPLQRLRIVRGTQLFEDNYALAVLDNGDPLNNTTPVTGASPGGLRELQLRSLTEILKGGVLIQRNPQ
LCYQDTILWKDIFHKNNQLALTLIDTNRSRACHPCSPMCKGSRCWGESSEDCQSLTRTVCAGGCARCKGPLPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACPYNYLSTDVGSCTLVCPLHNQ
EVTAEDGTQRCEKCSKPCARVCYGLGMEHLREVRAVTSANIQEFAGCKKIFGSLAFLPESFDGDPASNTAPLQPEQLQVF
ETLEEITGYLYISAWPDSLPDLSVFQNLQVIRGRILHNGAYSLTLQGLGISWLGLRSLRELGSGLALIHHNTHLCFVHTV
PWDQLFRNPHQALLHTANRPEDECVGEGLACHQLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVNARHC
LPCHPECQPQNGSVTCFGPEADQCVACAHYKDPPFCVARCPSGVKPDLSYMPIWKFPDEEGACQPCPINCTHSCVDLDDK
GCPAEQRASPLTSIISAVVGILLVVVLGVVFGILIKRRQQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQL
MPYGCLLDHVRENRGRLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHAD
GGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVSEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDAEEYLVPQQGFFCPDPAPGAG
GMVHHRHRSSSTRSGGGDLTLGLEPSEEEAPRSPLAPSEGAGSDVFDGDLGMGAAKGLQSLPTHDPSPLQRYSEDPTVPL
PSETDGYVAPLTCSPQPEYVNQPDVRPQPPSPREGPLPAARPAGATLERPKTLSPGKNGVVKDVFAFGGAVENPEYLTPQ
GGAAPQPHPPPAFSPAFDNLYYWDQDPPERGAPPSTFKGTPTAENPEYLGLDVPV
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