(FKBP1A) FK506 binding protein 1A, 12kDa [Homo sapiens] |
|
|
|
|
|
|
Gene
Transcript(s)
Exon(s)
Protein(s)
|
|
Accession
|
10409
|
Official symbol
|
FKBP1A
|
Official name
|
FK506 binding protein 1A, 12kDa
|
Gene type
|
gene with protein product
|
Organism
|
Homo sapiens
|
Location
|
Chromosome 20 (NC_000020.10) : 1349621...1373815 (-)
|
Map
|
20p13
|
Length
|
24195 nt
|
NM_054014.2
|
FKBP1A, mRNA isoform 12A
|
NM_000801.3
|
FKBP1A, mRNA isoform 12B
|
Accession
|
Name
|
Organism
|
Length
|
P62942
|
Peptidyl-prolyl cis-trans isomerase FKBP1A
|
Homo sapiens
|
108 aa
|
D3DVW6
|
FK506 binding protein 1A, 12kDa, isoform CRA_a [submitted name]
|
Homo sapiens
|
108 aa
|
Q0VDC6
|
FKBP1A protein [submitted name]
|
Homo sapiens
|
145 aa
|
| |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Synonyms |
PKCI2; PPIASE; PKC12; FKBP12C; FKBP12; FKBP1; FKBP-12
|
Alternative name(s) |
fK506 binding protein 1A, 12kDa; FK506-binding protein 12; immunophilin FKBP12; rotamase; peptidyl-prolyl cis-trans isomerase; protein kinase C inhibitor 2; FK506 binding protein12; FKBP12-Exip3; FK506-binding protein, T-cell, 12-kD; FK506-binding protein 1A (12kD)
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Summary |
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed. [provided by RefSeq].
|
|
|
|
|
|
|
|
|
|
|
|
|
Related Articles in PubMed
|
|
|
|
|
|
|
|
|
|
|
|
Go to ensembl
|
|
|
|
|
|
|
|
|
|
|
|
1 |
TTCCGGGACG |
TCGCGCGCCG |
TGTGGGGCGC |
GCACGCAGGG |
CTGGGCGTGA |
GGGGGCGTGC |
GCGTGCGCAG |
GCGACGCGCC |
|
81 |
GAGGTACTAG |
GCAGAGCCGT |
GGAACCGCCG |
CCAGGTCGCT |
GTTGGTCCAC |
GCCGCCCGTC |
GCGCCGCCCG |
CCCGCTCAGC |
|
161 |
GTCCGCCGCC |
GCCATGGGAG |
TGCAGGTGGA |
AACCATCTCC |
CCAGGAGACG |
GTGAGTAGTG |
GCGCGCGGCG |
GCTCGGAGTA |
|
241 |
CCTCTGCCGC |
CGCGCGCATC |
GGCTCAGCAT |
GCCCGTCTCT |
GTCTCCTCAG |
GGCGCACCTT |
CCCCAAGCGC |
GGCCAGACCT |
|
321 |
GCGTGGTGCA |
CTACACCGGT |
GAGTCGGGGG |
CCCAGCGGGG |
AGGGGGCCCG |
GGCCGCAGTC |
CGCAGCCCGG |
GTGCGGCTGG |
|
401 |
CCGTCGAGGC |
CTGGGGGCCC |
GGGGCCTGGG |
GTCCGGGGCG |
TGGCGGCGGC |
GAGGTCCGCA |
TGGCCCGAGG |
CTGAGGCCTG |
|
481 |
GGCGGTGGCT |
CAGGGGCAGC |
CTGGGGCTTG |
CGGAACCCGG |
GCGGGTCTGA |
ATCGGCGGCT |
GTGAGCGTCG |
GCTGCGGGCT |
|
561 |
AGGTGTTATC |
TGACCCGTCA |
GAAGCATTTC |
TGCACCTTAG |
ATGCTGCCCT |
TATGCCCGCT |
GCACAGATGA |
GGAAACTGAG |
|
641 |
GCTTGGCGAG |
GCGAAGTCAC |
TTTCCCAAGG |
TCTCACTTTC |
CCAAGGTCAC |
ACTTTCAGGA |
ATGGGCAGAG |
CTCTGGCCAG |
|
721 |
GGACCATTAG |
GAAGGATTTG |
TACCATTTCT |
GTGCCCCTGC |
CCCCACTTCC |
ATCCCTCCCT |
TCACTGGAGA |
TGAGGACGAG |
|
801 |
GTAATTCCGA |
GTCTGCAGAG |
CTGCTGCTTC |
CTCCGGGGAA |
CTCGGAATTC |
GCCCCTTTGC |
CTAGGGTGGG |
GAAACATCCC |
|
881 |
ACTTCCTAAG |
TCATTGCTTT |
GGCCCTTCCT |
GGCCTTGGGG |
GAAGTAGAGC |
TGCACGGCCT |
TCTTCCGTCT |
TTTTACTTTT |
|
961 |
GAGCCACTTA |
CAAATCCAAG |
GCTCAGTGAC |
AGCGCTGGCT |
CAGGCTGACC |
GAAAGCTGCA |
CGTGTAATTT |
AGTCCCCCAG |
|
1041 |
CTCTTCTAGA |
AGTAGAGACT |
TTTCTCGTCC |
TCATTTTAAA |
GATAAGCATC |
TGGAGGCTAA |
TACATAGTGA |
TAATACAAGC |
|
1121 |
CAAAGGAAAT |
TTTAGACACC |
TCCCCCTCCC |
CAGCCAGAAT |
TCAGACATCA |
GAGTCGTGTG |
CCTTGGGGCT |
GTCTTACTCC |
|
1201 |
TTCTCCTTAC |
AAGCTTGTCC |
TGGTTTGTAT |
GGGGGCGGGG |
GAGGGGGAGA |
GCTGAGTTGG |
CGGAGACTCA |
GTGGCTGTGG |
|
1281 |
GTCCCACAAG |
GGTGGCAGTG |
ATTGGTGTAG |
CCACAGTTGT |
TGATACGAAT |
AACCTTCCCT |
CCCCCTCCTC |
CTTCCCCTTT |
|
1361 |
CTCAACCTTC |
CCACCCTTTC |
CTCTGTTCCC |
CCTCCTCCTC |
CCTCTTTTTT |
TCCCACTCCC |
TCTCCTCCTC |
TTCCTCCTCC |
|
1441 |
TGGGTAGTAG |
GCTGTGGGCA |
GTTCTGGCCA |
AGTTGCTCAC |
GAATAAGCTC |
CACCTTTCTC |
TTCCAAATCA |
TGGAAACATG |
|
1521 |
GAGGGATCCC |
TCTATTGAGG |
GAAATGACTT |
TCACTGGAAA |
GAGGAAAAGG |
CAACTAACAT |
CCCCCCTCCC |
ATGCCCTTTT |
|
1601 |
ATTTCTGTGG |
CCCTTCCCCG |
TGGGTAGAAA |
TGGGGGCAGG |
AGGTAGAAGT |
TAAGGACTAG |
AACTTTAAAA |
ATTCTGCCAA |
|
1681 |
AGGAGGAGTT |
ACTGAAACCC |
ATCTTTCTGG |
GGAGCAGGCA |
GTCTCATGTC |
CGTGAAGGAA |
GCTGGAAAGT |
GCTTTTGATG |
|
1761 |
TTTTAGATAG |
CTGTCCTTGT |
AGGCCACAGT |
CAGCACCTGA |
GCCTGGGAGG |
TCTGGTAGAT |
GAAAGCGCAT |
CCTTTTGGTG |
|
1841 |
ATTTGTCATC |
GGAAGGATGA |
GGAGAGTAAC |
CATTTACAGT |
GCTGGGGTGA |
GTGGGCAGTT |
CATTCAGTTC |
CGCAGCCAAC |
|
1921 |
TGGGGCAAAG |
ATTGGGACTC |
AAGCCGTGAG |
GAGCTGCCTT |
CTGCCGCACC |
CCCTCCCCAC |
CCTAGCTTGT |
ACATAGCCAC |
|
2001 |
ACTAGGGTGC |
TTGGCAGCAT |
GTGTCCCACT |
CCCACGTCTG |
CCCCTCATGC |
TCGCCCATGT |
TCTGGTGCTG |
CCAACAGGAC |
|
2081 |
TGGACCCCAG |
CATGTAGGCA |
GTGCCGCACT |
TCACCATGTC |
TCTTTGTGAA |
ATATCCCCAC |
ACAGCATGTC |
TGGAGCCTTT |
|
2161 |
TCCTATGAGA |
ACAGATGGTC |
ATGAGACCCA |
GAACACCATC |
AGGGTTTCCA |
GTGCCTCTTG |
AAGTGTGTGT |
TTTTCTCGCG |
|
2241 |
GGTGGCACGC |
ACCCACATGT |
TTCCAGAGCA |
GCAGCAGGAC |
CCTGGCATGC |
ATTAGGACAA |
AAGCTTTCTT |
TTTGATTTCG |
|
2321 |
TTTTGATAAG |
CCCTATAAAG |
ACGCCTTAGT |
GAGAAGCCAG |
CTCTGCCTCA |
TGCTCACAGA |
ATAGACTGTT |
TTCGAGCAGG |
|
2401 |
CTGGTGGCTT |
TGTTCCCGTG |
GGTCTTTGTC |
ACCAGCCTCC |
CAGGAATAAC |
CTGTTTGAGA |
CCTGTGGGGG |
CGTGAGAGGA |
|
2481 |
GTGGGTAGGC |
ACTGGGAGAT |
CTCATCTGTA |
GCAGTTAAGG |
CTTTTAAGTC |
ACTGGGAACA |
GAATCCATCT |
TGGGGGAACA |
|
2561 |
TGATCAGAAG |
GTGGAGGTTA |
TAAAGGTTCC |
AGGGGTTTTC |
AAAGGCAGAA |
GCCCACTGGG |
TCCTAAGAAG |
GGAAAAGAAA |
|
2641 |
TAATCATGAT |
GCCTCTAGTT |
CTCATCTCTG |
TTTTTTGGTT |
GTTGTTTTGT |
GTTTTGTTTT |
GTTTCCTGCC |
TGACTGCCTC |
|
2721 |
AGTAGTCTCC |
TGTTAGAGAT |
TTGTGTTTGT |
CTGCTTCTCC |
CAACTGGTGG |
GTGGTGGAAG |
TCCCCTGCAT |
GCTCCCCCGT |
|
2801 |
CCCCCCTCCC |
CCCTCCCCCC |
TCCCCATGGC |
CAGCTTCTCT |
GTCTTCTTTT |
GAGTATCTGG |
CTCAGATTTC |
TTGGCTGTGA |
|
2881 |
TTCTGATTGT |
TACTTCTCTG |
AGAAGGAGAG |
TTTGAGTAAG |
GTGAACACTC |
TTGATCCAGT |
CAGCTCTTGC |
CAGGTGTCCA |
|
2961 |
CTCAGCTGAT |
TTGGGCACGG |
GTCCAGAGAA |
AGAGGCGTGG |
AAGTAAGGTG |
GCCAAAATCT |
CCCCTTAGCC |
ATCACAGGTG |
|
3041 |
TGCAGAGCAC |
AGACTGACCT |
TTACCACATG |
GATGCTTTAA |
ATGCCACTAA |
TGGCTGTCAG |
TCACCTTGAT |
GTCACTCTCA |
|
3121 |
AGGGTCCCTC |
TGGTGACTTC |
CGTGACCTTC |
TGGCAGAGCA |
CAGCATGAGC |
AAGGCCTCAA |
AGGAATGCCT |
GCACTACCTC |
|
3201 |
TGTGGTACCA |
GAGGGAAAAT |
ACAAAGTTCA |
CTATCACCAG |
CTAAGCATCT |
CCTAGGAGCA |
TGACAGGCAT |
TGAGGTGGGA |
|
3281 |
GGGAGGTGGT |
GGAAAGGTAA |
GCTGCCAAGT |
AAGTGCCTTT |
AGGAGCCAGG |
GAATTCTCAT |
GGCGCCTCCC |
TGCTGCCTCC |
|
3361 |
AGTAGCTTCG |
TCATCTTTAC |
TGTTAGCTTG |
TCCTGGCACA |
CAGCTAGGTT |
TAGACCTCTT |
TTACTTACTT |
CAGCAGGCCG |
|
3441 |
TGTGCCTGCC |
ATTGTGAGAG |
CAGCCCCAAG |
GGGATTGAAG |
GAATGTTTTC |
TTTTTTCTTC |
TTAAAAAGTA |
ACTAACTGGA |
|
3521 |
CATTTTGTCC |
TTGGGATCAG |
GTTTAAGTCA |
GGTATAGCCT |
CCCGGTTTCT |
GACTGAGAAA |
AACCAGGAGC |
CCCTCAACCT |
|
3601 |
CATGTCCTCA |
GGAGGTTGAC |
TGGGAAGGCT |
GCTGAGGCTC |
CCGGGACAGG |
TGTGGCCACT |
TTGCTGCAGC |
CTCCCTCAAG |
|
3681 |
CCCCTTGCTT |
TTCCTTAGCT |
TTGTTCCCCC |
CTCTCCTCTG |
CTTTATTCCA |
TCCACTCCCT |
TGCTAGGTAT |
CTCTTGGTTG |
|
3761 |
GTGATCTGAT |
GTCTGGAGGG |
AGGCTCACCC |
TCAGCAGAGA |
TGCCTCAGAT |
GGCTTCCCCT |
GACGTGTGCT |
GTCTTGAGGC |
|
3841 |
ACACAGGCTG |
TAACTGTTGG |
GCAGGGCTGC |
AACAAGTCCC |
TTTGCCTTCC |
CACAGCAGAT |
GTTTTTTGAG |
CAACAGCAGC |
|
3921 |
AAGCCAGGCT |
CTAGGGACAT |
GGCTAGTGAA |
CTAAATAGAC |
AAAGACCTGA |
TCTGGTGGGG |
CTTTGCTTAT |
GATGAGGAGA |
|
4001 |
CTGATAGTAT |
GGCCATGGAG |
CACATCAGGT |
AGTAAGAAGC |
GCTGGAGAGA |
TTAAAGCAGA |
GTGAGGGATG |
GGAAGGGAAG |
|
4081 |
TTGGCTGCTT |
TTCGTGAGGG |
TGATTGGAAA |
AGGCCTCTGA |
AAAAAATGGC |
ATTTTAACAT |
TCACTCAAAG |
GACATTGGAG |
|
4161 |
AGGGAGCTAC |
AGGGCTGTCT |
AGAGTATCCA |
GGCAGAGGGA |
AGAGCTAGTG |
CAGGACCCTG |
AGGCTGGAGC |
CTGCTCGGTG |
|
4241 |
CATTAGAGGA |
ACAGTAAGAA |
GACCGGTGCG |
TTAGAGGAAC |
AGGAAGTGGA |
TTGTGTGAAA |
GGGTATGTGG |
CAGGAGATGA |
|
4321 |
GGGGATGGTG |
GAGCCTCGTT |
GGTTTTTATA |
AAAACGTTGC |
CTTTTTCTAA |
CTCAGGTGAG |
AGCCACTGGC |
TGGCTTGGCT |
|
4401 |
TTTAATGCCC |
GCCCCCGCCC |
CCCCAACCCA |
CGCTCCTTCT |
GGCTACTGTG |
TGGACAATGG |
GCTTTTGGGG |
GCAAAGGCAG |
|
4481 |
AAACAGGACA |
CTGGTTGTAT |
CCCAGGTGTG |
TGGAGTGCCA |
GCTCAGGCAG |
TGGGCAGAAG |
TGGTGCCAGG |
TGGACAGTGA |
|
4561 |
TCCCCAAAGA |
GCATGTGGGT |
TCTTCGCTGT |
GTTCTGATCT |
TGACCCTGCC |
ATACAACGGG |
CTATGAGAGC |
TTGAACAAAT |
|
4641 |
TGTCCCACAG |
TTCCCAGCTT |
CCACATGCTG |
TCTATAAAAT |
GGGAGTAACG |
ATGCCTGCTG |
TGAAGCAAAT |
GCCTATCGAG |
|
4721 |
ACTACCCAGT |
TGTCTCCAAA |
GTGTTGCTCT |
TTTTTAAAAC |
CACAGTTCCA |
TTGAGCCTCA |
CTCATCGCAG |
TTGTTATGTC |
|
4801 |
TGTAATCTCA |
GTCTAGAAGA |
GTCCTTACGC |
TGTTTTTTTC |
TTAATAACTC |
TGATTTCTTC |
AAAGAGAGCA |
GGCTAGTTAT |
|
4881 |
AGAATACTCC |
ACATCTGTCT |
TACTGTTTTC |
TCATGGTATT |
GTTTAACTTG |
TTCCCTGCCT |
TGATTTTCTG |
AACCGGATGT |
|
4961 |
TTAATCTTTT |
AAGTGTCTGA |
ATAGATTCCG |
TTTAAACATT |
TTAGTGTGAG |
TACTTCATCC |
TCAGCACACA |
TGGGAAACAT |
|
5041 |
CACTAGTTGT |
GATGCTAAAT |
TTGATCTTTT |
CTGTAAAGGT |
ACATTTTTCC |
CTTTGCATTT |
AGCAGTGATC |
TGTGGAGTGC |
|
5121 |
TTAGGTAGCC |
ATAGATGGTC |
TCTTGCTCAT |
CAGCCTTTCA |
CCTAGTGGTG |
TTTACACCAT |
CTGATCATTC |
TCCCCTGAAG |
|
5201 |
AAGTCACTGG |
CATTCACAAA |
GTGTTGATTT |
TTAAAATTCC |
TTCATTCTTT |
CTAAATTTAT |
TAGCTGTTAT |
CCTTCTATAA |
|
5281 |
GATAAGGTAA |
AGTAATTCTT |
TACCTTTAAA |
TACCAAATTT |
TATTTTTATT |
TTTTGAGACA |
GTGTCTCTGT |
CACTCAGGCT |
|
5361 |
GGAGTGCAGT |
GGCTTGATCA |
TGGCTCACTG |
TAGCCTCGAC |
CTCCCAGACT |
CCCATCCCGG |
CCTCCCATCC |
GGCCTTCTGA |
|
5441 |
ATAGTTGGGC |
ATACAGGTGC |
ATGCCACCTG |
TCCTAATTTT |
TGTATTTTTT |
GTAGAGACGG |
GTTTCGCCAG |
GTTTCCCAGG |
|
5521 |
CTAGTCTCAA |
ACTCCTGGCC |
TCAAGTGATC |
CACCCTCCTT |
AGCCTCCCAA |
AGTGCTGGTA |
GTACAGGCAT |
GAGCCACCGT |
|
5601 |
GCCCAGCCTT |
TAATTACCAA |
TTTTTAAAAT |
GAAAAATGAA |
TGTTAACTGA |
TGGGGTATTG |
CCATTCCCAG |
TGGGGGCAAG |
|
5681 |
TGACTTTTTC |
CCCCTCTATT |
TGCTTTGACT |
GTACTGTGGG |
CTGAAATTTT |
TTGTCAGGGC |
CTTAAGATCA |
ATGATACCCA |
|
5761 |
TTATTCTTTT |
TGATGCTAAT |
ATCATCCTAA |
ATTTGGCCAG |
TAGGAGCCCT |
TTAAGCTGGC |
TCCAGTACCT |
TTTTGACAGG |
|
5841 |
CTCCCACCAT |
TCCTTCATCC |
ATTTCTCGGT |
TTCACTACTC |
TGGTCCAATT |
ATCAGCCATC |
TTTCAAAGAG |
CTCTGGTTCC |
|
5921 |
TTTCAGTGGG |
GTCCATGACC |
TTTTTTTTTC |
TTGGTAACAG |
CTTTATTGAA |
TATAATTTAC |
ATACCATAAA |
TTCACCTATT |
|
6001 |
TACTCATAGA |
TGTTTTAACT |
AGAACATTTT |
TAGGCTTAAA |
CTGATTTTTA |
TGAATTACTG |
AGGGGTTTAT |
TGTATCCATA |
|
6081 |
AACTGGAAAT |
CATTTGTCTG |
CCTTGGAATT |
TTCTCTAAAA |
ATATTGTCAC |
CTGCTGTTTC |
CCATGGAAGA |
AGCCAAGGTT |
|
6161 |
ATGAATAACT |
TAATCACATA |
GCATTCAGTT |
CTCCCTTTGG |
TGCTCATGGT |
GACATTTGTT |
TATTTTTACT |
TCTATTTTTT |
|
6241 |
CTTCTGTTTT |
TTTGTTTTCT |
TTTCCTGCTA |
AAAAGCTTAA |
CCAAGTCTCT |
GCATTCCCTC |
CCCTGGACCC |
CTTTGATTTT |
|
6321 |
GACCAGGTGT |
ATTCTAGCAG |
TGCAGAAAGT |
CGGGGAGGTA |
GAAATAACCA |
GTTCTTAGAT |
GCTACTGTCT |
CTTTCTGTTA |
|
6401 |
CATTTGCTCT |
TCCTCTCCCA |
GGAGCTCAAG |
CCACCTTGGC |
CTGCATTCAT |
TCCTCGAATG |
CTCCAAGCCT |
TTTCCCACAT |
|
6481 |
GGAGGTCTCT |
GCCCCTTTGC |
TTAGGTGCCA |
CCACACTGCC |
CCCACTCCCC |
ACTGCATGAC |
AGGCTCTTTT |
CTTTATAGCA |
|
6561 |
CAGCTTAAGT |
AACACTTTGG |
ATGCATACAT |
GCATGCTTCT |
AATTCTGCAA |
CAATGCACCC |
ATCTATTTTC |
TTAGCCCCCA |
|
6641 |
TCATAGTCAG |
GATCCGTGTA |
GTTAAACATC |
TGCTCTTTCC |
CCAACCGACT |
GAAGGCTCCA |
GGAGGCCAGA |
CCCACACTAG |
|
6721 |
TGTTGTTCTC |
CAAGGTCTCC |
CCATCAGTCT |
TGGCATAGAG |
TAGCTATTCA |
GTGACTGTTT |
GAATGAGTGG |
CCAGTTAGGA |
|
6801 |
CCTGGCATTC |
CCTCGGTCAC |
TCAGTGAATA |
TATAAGGAGC |
TGGGCAAAGC |
CTCAATGTTG |
CCCTCAAGAA |
GCTTACCCTG |
|
6881 |
TAGGGAGTGG |
TCAGTTACAA |
TGAAAGTACC |
TCAGGCAACC |
TACACCTATA |
GGCTAGAACT |
TCTTGGAGGA |
AGTGCCATTT |
|
6961 |
GGTCTTGGGT |
GTGTATGGTG |
CAGTCAGGCA |
GGAGGAAAGC |
GTCTTCCAGG |
TATATACACA |
GGCCAGGAGG |
AGAAAAGGGT |
|
7041 |
ACCTTTGATA |
TTTCTGTAAG |
TACTTGATGA |
ATGTCTGCTA |
TGTACAAGAC |
ACTGTCCTGG |
CTACCAAGAA |
TTTAGGAGTG |
|
7121 |
AAGAAGACAC |
AGTTCCTGCC |
TTCATCTCAC |
ACTGTAGTGG |
AAAAGACATA |
ATAAATATGA |
TTAATAAGCA |
AGACTGTTGT |
|
7201 |
GTATAAGCTA |
GTAAGTGTTA |
AGGAGGGAAT |
AGGAAAAGGT |
TGAGGTTTTA |
GATAGATTGG |
CAAAGGCCTC |
AATGAGAAAG |
|
7281 |
TGACATTTGA |
GCAAAGACTT |
GAAGGAGGTA |
AGGATGTAAC |
CTATGTGACT |
GTTTGAGCAA |
GATCATTTTA |
GGCAGAGAGA |
|
7361 |
ACAGCAAATG |
CAAAGGCCCA |
CGGGTGGAGG |
TATCCCTGGT |
GTGTATGTAG |
AACATAAGGA |
AACAATGTTC |
TGGGACTGGA |
|
7441 |
AAAGTACAAG |
AGTAATCAGA |
GGTGAAGTCA |
GAGGGATGGT |
GGTAGGGGCG |
GAGGCTTGAC |
ACTTCTTAGA |
GGGTCTTGTA |
|
7521 |
GGCCATTTTA |
AGAGTTTTAT |
CTCCTGAGAT |
GGGGGAGTCA |
CAGGAGTTTT |
TCAGCCGAGG |
GGTAGTAGGG |
TCTGGCTGCT |
|
7601 |
GTGTCAGGTT |
TAGACTGTAG |
GAGAGCAAGA |
GCAGAAGCAG |
GGAGACCAGG |
GAGGGAGTTG |
TAATAATAGT |
CTGTAACAGA |
|
7681 |
GGTCCAGAAC |
TCATGCCTTT |
AACCATTATA |
CCCTATAGAA |
AATGCATATT |
TCTACCACTT |
CCAGCTAGCT |
ATTGTTAAGT |
|
7761 |
GGTATTTCTT |
TTGATTTTTT |
TGGAGATGGA |
GTCTCACTCT |
GTCGCCCAGG |
CTGGAGTGCC |
CTGGTGCAAT |
CTCGGCTCAC |
|
7841 |
TGCAACCTCT |
GCCTCCCGGG |
TTCAAGCAGT |
TCTCCTGCCT |
CAGCCTCCCA |
AGTAGCTGGG |
ACTACAGGCG |
CACGCCACCA |
|
7921 |
TGCCCGGCTG |
ATTTTTTGTA |
TTTTAGTAGA |
TACAGGGTTT |
CACCATGTTG |
CCCAGGCTGG |
TCTCAAACTC |
CGAAGCTCAG |
|
8001 |
GCAGTCCACC |
TGCCTCAGCC |
TCCCAAAGTG |
CTAGGATTAC |
AGGCGTGAGC |
CACTGCACCC |
GGCCTAGTGG |
TATTTCTTTC |
|
8081 |
TCCCCCTCCC |
CATGCGATAT |
AATGTGGTAG |
TAACTCCTCT |
TATTTATACT |
GTGATTAAAG |
TGGAAAATGG |
AGAGACACAC |
|
8161 |
CCACAGGGCA |
TGCATTCTGG |
TCTGTGTTCT |
TTTTATTGCC |
GTTGGATCCT |
GCATATTCTT |
CCCATCATGG |
GCCCTGCCTT |
|
8241 |
TGAAAATACA |
CTTTTGGTTA |
TAGGATCTAA |
AGGGATTTAG |
CCAAAGGTTA |
GAAGCATTTC |
CATACTGCGT |
ATGGGAAATG |
|
8321 |
TGCTTGCACT |
GTTGGTGATC |
TCAGGAAAAT |
GATAGTGAGA |
GTGAGCTGGT |
TCCCTCTTTG |
GGTTGGCACT |
TGGACCTTTG |
|
8401 |
GTCATACCCC |
TCACTCATAA |
GGAGTTCTCA |
GAACCCCACT |
TCAGGGAGGT |
TGTGCTGGAA |
TACAGCCACA |
GAGACCCAGA |
|
8481 |
AATGGAATAA |
TAAGAATGTA |
AGATTTGAAT |
TTGTATCTTT |
TGCCTATCTA |
AATGTAGAAT |
CCCTTTTTAC |
CCATCATGAT |
|
8561 |
TGAGACAAGT |
GGGTAGTTGG |
TATGCTAACA |
TAAAAGTGAC |
ATGGCTTCTG |
TAAACATTTG |
ATTTCAAACT |
CTAACATAAA |
|
8641 |
TCATTTGCTA |
AAGGACTATG |
TCTTTATCTT |
TGAGGATGGC |
TCTGCTAGTG |
GAGTTTCCCA |
TCATAGTTCT |
TGCAAAAACC |
|
8721 |
AATTTGACCT |
TTTTTAAAGT |
AGAGCAAAGA |
GTATTGTGAG |
AACATTTAAA |
AACCAAACCT |
TTCCAGATTT |
TTAAGATTTC |
|
8801 |
TTTCTCTAAA |
TGTAGTCTCC |
CATATGATTA |
TTCACTAGCA |
ATAGTTTTTT |
AGTGACTTGC |
CTTTATTGAG |
TCTTTCCCAG |
|
8881 |
GAGTCAGCTA |
GAACCGCTGT |
TTGTATTCAC |
ACTCATTTTA |
TTGATTTACA |
TACTATTTAA |
TTACATTATA |
TTTACACAGT |
|
8961 |
AAATATAGCT |
ACCATAAATG |
GATTTGGGGA |
CAAACACAGC |
TAACCACTCC |
TCCCTTTGTG |
AACACAGAAC |
TCATATGGGA |
|
9041 |
ATGAAGAAGT |
GATCATGAGC |
TAGAGACTAA |
AGCATGAGGG |
GAGTGCTCTT |
CACTATGCTG |
GGGTACGAAG |
GCTGTGAGTT |
|
9121 |
TTATGAGTCT |
CCAAGTAAGG |
CAGCTGAGTA |
AAAGGTGGTT |
AAGAGAACTT |
CTGTGTCTAA |
TAAGAAGAGG |
GAAAGCAAAC |
|
9201 |
AGCTAAACCA |
TTAGACCTTG |
AGCCATACGC |
CCATCTGGGA |
ATGTTCTGAG |
TGGCTTCAAA |
TGCAAAGCTG |
CAGAAAAATA |
|
9281 |
CTGGCTCCCC |
CTACCTCCAC |
CCATTCAACC |
ATTACACCTT |
TTTTTTTTTT |
TTTAAGAGAC |
AGAGTCTCGT |
TCTGTTGCCC |
|
9361 |
AGTCTGGAGT |
GTACTTGTGC |
GGTCATAGCT |
CACTGCAACC |
TCAAACCTCT |
GGGCTCAAGT |
GATCTCCCAC |
TTGATCCACT |
|
9441 |
CAAGTAGCTA |
GGACCATGTC |
TGGCTAAATT |
TTTTTTTTTT |
TTTTTTTAAT |
TTTTTGCAGA |
AACAGGATTG |
GGGACATGAG |
|
9521 |
TCTTGCTGTG |
TTGCCCAGGC |
TGGTTGCAAA |
CTCATGCCAG |
TCTCAAACTC |
CTGGCCTCAA |
GTGATTCTCC |
TGCCTTGGCC |
|
9601 |
TTCCAAAGCA |
CTGGGATTAC |
AGGCATGAGC |
CTCCTCCGCA |
GCTGGCCTCA |
TTGTACTTTT |
TGTCATTAAG |
AAACTCACCT |
|
9681 |
GCGTGTTGAA |
AGTAGAAATC |
CTTTTCCCTC |
TCCAAACTGT |
AAATGGCAAG |
GACTTTATTT |
TATTTTGAAG |
GTTTGGGGCT |
|
9761 |
TAGGATATTC |
TGGTTTTTTG |
TTATGTTTGA |
TTTTTGGTTT |
AGTTTAGTCA |
TTTTTTTTTT |
TTTAATCTTA |
AAACTTCCCA |
|
9841 |
TATTTTGTCC |
CTGTAAAATG |
CTGCCTATAG |
GAAACACTCC |
TGCAAAGATT |
CATGAGCAAC |
TATAAACTGC |
ATTGTGAGTC |
|
9921 |
ATGAGCTTTC |
ACTACAAGTA |
GTGAAGCCAT |
AAGTCTGTAG |
AGGTGCCTTC |
TTCAGTCCTG |
TTACCCAGTA |
GAAGGTATAT |
|
10001 |
GGCACTCTGC |
CCTTCCCCAA |
AGCAGAGTGC |
CTTGGAAGTG |
ACTCCATTTC |
TATTGGGTTA |
TTAGTGAAAT |
AGTATCCCAG |
|
10081 |
TGGTCCTTGT |
GAATCTCCAG |
GTCCTGGTCT |
TGAGTCTTAA |
CCACCGCTTC |
AGTGGCTTGA |
GCCAACCACC |
AGGAACACAG |
|
10161 |
TCTGGGGATA |
CTTTGCTGCC |
CAGGAGCTGC |
TGGCCAGGTC |
TCCCTCTGCT |
GATTCCTTGA |
AAAGCAACAG |
GAAAGAGCAG |
|
10241 |
GCTGCTGTGG |
AGTAGACAGA |
CTTGAGACTC |
TCTGCACCGT |
CTTGTTTTGT |
AAACCCTTTT |
GCTCCCTTTC |
CAAGGATTTC |
|
10321 |
AGTTCAGGAG |
GAGACCCAGG |
CGAAGATGAC |
GTCAACAGCC |
TCTGCATGCA |
GTCAGTCATA |
GCTTTGGCTT |
CTTTCATGGT |
|
10401 |
CTTGTGCTTT |
TAACTGGAGC |
ACATTTTCAC |
ATTTTTCTTA |
CTGATTAGTA |
ACTAAAGGTG |
CTTAAAGTAA |
AGTTTACCAT |
|
10481 |
TCTGGGATTA |
CCCCTCATAT |
TCTTGTTACC |
ATATAGGGAA |
GAAGGTCTAA |
ATATGAAGGC |
CTCATGCTTG |
TCCTTCTGGT |
|
10561 |
TCTTAAAAAT |
CATGCAAGTA |
AAGCAAATCC |
AAGAGTGCTC |
TTGAGTACCA |
GCACCATACG |
TGCCACCAGG |
ACACAGAACG |
|
10641 |
CAGGCCAGGT |
CTGTGAGCTT |
GGGCTGCATT |
CAGTCAGGAG |
AGCCAAGACT |
AAATACTTAA |
AATAAGAATA |
TGGAGCTATT |
|
10721 |
CCAGGCAGTT |
TGTTAGGCAT |
GAGTTATAGG |
CTTGTACGGC |
CAGGAATGAA |
ATTGGTCAGT |
TCTGCAATTA |
GAAGGCAATG |
|
10801 |
CTTGTGATGT |
TTTATGCTGA |
GTGGCCTTTA |
GAGCTTAAAG |
ACTGTCAGCT |
GTCTTGTCTG |
CACTGTAACC |
TCAGTTGCCT |
|
10881 |
TCTCTGAGCA |
GGGCACGCTT |
TCTTTAGGAA |
ATTATGGCAC |
TAACTTGGCA |
GGTGGTTTCA |
CTGTTCAAGG |
GCTCCAGCTC |
|
10961 |
CTGGCACAAG |
TGATCTCCAG |
AGTTAAAATT |
GGAGCAGCTG |
CTGAGACTTG |
ACTTGCTGCC |
TGCTTTACCT |
GTTCCCTCCC |
|
11041 |
CAAAGAGAGG |
AAGCACTTTT |
CATTCATTGC |
CAGTGTGTAT |
GTGGGAGCTA |
AACATATATA |
GCATTTTAGT |
AAATGCCACT |
|
11121 |
GCCTACTCTT |
TTTCTTTTCC |
TTTTTTAAAA |
AAGTTACTGA |
GGCGTGATTG |
AAATCCAATA |
TACTGCACAT |
TTTAAAAATG |
|
11201 |
TACAGCTTCA |
TAAATTTTGA |
TGTGTCATTG |
TTTCCCTTTG |
AATTCACCCC |
TCCTTACCCT |
CCTCTAACAA |
CTACTGATAT |
|
11281 |
GCTTTTTTGT |
CAGTGTAGAT |
TTGTTGCATT |
TTCTAAAGTT |
TTATATAAAT |
GGAATCATAC |
AGTACGTTCT |
CTTATGTCTG |
|
11361 |
CCTTCTTTCA |
CTTGGTATAA |
TTATTTTGAG |
ATTCATCTGT |
ATTGTCCCAT |
GTATCAATTG |
TTTGTTCCTT |
TTTGTTGCTA |
|
11441 |
AATATTTTTC |
TATATATAGA |
AACATGTATT |
TACCAACTTA |
CCCGTTGGTG |
GATGTTTGGG |
TTAGTTTATA |
GTTTTTGACT |
|
11521 |
ATCGCTAATA |
AATCTGCTTT |
GAACATTTGT |
GTACAAGTTT |
TTCTGTGGAC |
ATAGCCTGTC |
ATTTCTCTTG |
GATAAATACT |
|
11601 |
CAAGATCAGA |
ATGGCTGGGT |
CATATGGGAG |
GTGTATGTTT |
AACTTAACTA |
TCAAGCTGTT |
TTCTGAAGCT |
TTATGTTATA |
|
11681 |
TTCCCACTAG |
CAGTGTATGA |
GAATACCAGT |
TCCTTCACAT |
CCTCACTAAC |
ACCTGACGTG |
GTCAGTCTTT |
TTAGCTTTAC |
|
11761 |
TCATTCTAAT |
CAGTGGTGGT |
AGATGCGTTT |
CCTAGTGGTT |
TTAATTTGCG |
TTGTTATAAT |
AACTAGGAAT |
GTTTAGCATC |
|
11841 |
TTTTCATATG |
CTTACCTGCC |
CTCTGTCTTT |
TTCAATGAAG |
TATCTGTTCA |
AATCTTTAGC |
CCTTTTTTAT |
TGGTTTTCTT |
|
11921 |
AATTGTTGAA |
TTTTGGTTTG |
TTATATTCTG |
GATATAAGTC |
CTCTATCAGA |
TATGTACTTT |
GCAAAAGTTT |
TCTCCCAGTG |
|
12001 |
TATGGTTTGT |
CTTTCATTTT |
CTTAACAGTG |
CTTTTTAAAG |
TACTGAATTT |
ATTTTGATGA |
AGTTCAATTT |
ATTCTTTTAT |
|
12081 |
AGATAGTGCT |
TTTTGACATC |
ATACTAAGAA |
ATCTTCACCC |
AACTCGAGGT |
CACAAAGATT |
TCTTTCCTAT |
GTTTTCTTCT |
|
12161 |
ATAAATTTGA |
TAGGTTTAGT |
ACTTAACATT |
TAGGTCTAGG |
ATCCATTTTG |
AGTTAATGCT |
TGATAATGGT |
GTGAAGTTTT |
|
12241 |
TACTGTGTTA |
TGTGTGGATA |
TTTTGTCATT |
TCAGCCCAAT |
GTAATTTTCA |
TCTCAGACAT |
TGTAGTTTTC |
ATCTCTGAAA |
|
12321 |
GTTGGAGTCT |
TATGGTTCTC |
CTCTACTAAT |
TCTAACATTT |
GTGTTAGTTC |
TGGGTTGCTT |
TCAATTGATT |
GATAAGTCTC |
|
12401 |
CTCATTGTGG |
GTCCTGTTTT |
CTGCCTCTTT |
GCATGCCTGG |
TAATCTTTGG |
ATGCCAGACA |
TTGTGAATTT |
TGCCTTTTGG |
|
12481 |
GGTGCTGGAT |
ATTTTTATTC |
CTATAAATTT |
TCCTGAGTTT |
TATACTGAGA |
AGCATTTAAG |
TTACCCGGAA |
ACAGTTTGAT |
|
12561 |
GCTTGCGAGT |
CTTGCTTTTG |
TGATTTGTTA |
GGTAGGTCTA |
GAGCTCAGTT |
TAGGGCTGAT |
TATTTCCTAC |
TATAGGCAAG |
|
12641 |
ATCTTCCTGA |
GTATTCTGCC |
CAGTGCTTTG |
TCAATCATGA |
GCTTCTCCAG |
TTTGACCGGG |
GGGTAGTAAG |
CACTAATCCT |
|
12721 |
AGCCCTGTGT |
GAGCACTGGA |
TACTGTTCCT |
CTAAGCCTTT |
TGGATAGTTC |
TTTTCCTGGC |
CTTGAATAGT |
TTGCTCAGAT |
|
12801 |
ACATGCACTG |
AGAGGGACTC |
TGCTGAATAC |
TCAAAGAGGA |
CCCTGCAGAT |
CTCTGGGGAT |
CTCTGTATAG |
CTCTCTCCTG |
|
12881 |
CTGGTACTGT |
GTCCTATGGA |
CTCTAGGTGC |
CTTGAGCTCC |
ACTCCAGGTC |
CCTCTCCCTG |
GAAACTCCCA |
AGGATATAGG |
|
12961 |
GCTGCCCTTG |
TTTCCCATGT |
CTCAGGATTT |
ATTGTTCTTC |
ATTACAGATG |
TCTGGTGTCC |
TACAAACCAT |
CGTTGTAGCT |
|
13041 |
ATTTTGTCTA |
GGTGGTTTTT |
AGGTTTTAGT |
GGACTTTTTG |
TAGGGAGGAA |
GGGGTTGGTT |
GGTTGGTTGT |
TGGTTGTTTC |
|
13121 |
ATGAACAAAT |
CTGATCCTTG |
TCCTCCACCG |
TGACCAGAAA |
TGGAAGTTCT |
CACTATCTGT |
TTTGACATTA |
CAGACTGAAC |
|
13201 |
AGCATAATTC |
CTACACATGC |
ACACTCATTC |
CAGCTTAACA |
AACACTGCTT |
CCACCTTCTC |
CCCCAGGCTG |
ACAACTTAGG |
|
13281 |
GCCATAGATA |
AGTGGCCTGT |
TCCTCCCCAC |
TGGGGAAGCC |
CTCCTTCTCC |
TTGTCCTGTA |
GCTTGTGCCA |
GTTGTGTGAC |
|
13361 |
ACCCACTTAA |
TCACATACCA |
CCCCACCCAT |
TTCGGGGGAT |
TATTGTTTAG |
CTTTCGGACT |
CGATTATGGG |
AAATCCTCTC |
|
13441 |
CTTGGACTCA |
AGGAACCCCA |
ACATCACTGC |
CACCACCCAA |
CCCTGCCCTG |
CGAAGATTTC |
TCCTTAGAAA |
GTAGATGAGA |
|
13521 |
TTGACAGTTG |
GTGACTGTGG |
TCTGAAATTC |
TGGAGCAAGT |
CTCATGCCCC |
TTTCCCAGGG |
ACAACAGAGC |
ATCCAAAATA |
|
13601 |
GCATAGGAAA |
ATTAAGATCC |
TAGGCAAAGG |
TCCTGTTTAA |
AGCTCCTTTA |
CTTAGAAATC |
CTGCTTCCTG |
GCTTTTATGG |
|
13681 |
TTTTAAGATA |
CTAGGGAGAG |
GTTTGCCCCT |
CAGTGTCCAA |
GATAGGCTCA |
GGAGAGCTGG |
GGTTAGACAG |
GCATCCTCAC |
|
13761 |
ATAGAGCCAC |
TGAAGAACAT |
ACACATCTCC |
ATGCTGGCTC |
AGCAGCAGCA |
GCAGCAGCAG |
ATTCAGGCTG |
TGTCCTGCCT |
|
13841 |
AGTGCTCCTA |
GCCTGGTACC |
AGTCAGATAG |
ATAGTTGAAG |
TATCTCACCT |
CAGGCAAAGC |
AACATTGATA |
CATTGATGCA |
|
13921 |
TGTAGTGTCT |
GGAGGTTGCT |
TGGCATTGCA |
TTTGATCAGG |
AATAAAAAGG |
AAGTTTAGGG |
AGTCTGTCTC |
AGTACCCTGT |
|
14001 |
GGCTTTCACT |
GCAATCAAAA |
TACGATCTTG |
CACAGGTCAG |
AGCCGTGTTC |
AAGTTTGGCA |
AGAAATAAGG |
CTAATTTTTT |
|
14081 |
ATAGGTATAC |
CGTACTTTCC |
AAATTGTGGG |
TTATGAACCA |
TTAATGCATC |
ATGAAATAAA |
TGTAGTGGGT |
CACAATCAGC |
|
14161 |
ATTCTTTTTA |
AAAATGAGAA |
GTATATGCCA |
TGTAGTAACT |
TACATGTAAA |
TTTTGTTTAT |
ACACAGACAA |
AATGTGGGTG |
|
14241 |
TGTACTGGGT |
CCTGACATGA |
GACACTGTTC |
CCATTGTCGC |
GGATCAGGGA |
TAGTTCTTTG |
TGGTTTTAGT |
TGTTGAGTTC |
|
14321 |
TGTTTCTTTG |
TTATTCCTTT |
CGTGGCAGCA |
CTACATTGTA |
GCGTGCTCAC |
TAAGTGTCAG |
AGGTTTACCT |
CACGCCAGTT |
|
14401 |
GTGTTCATTT |
GGCTGCAGGT |
AACTGAAGAC |
CCAACCTAAG |
GCAAAGCAGA |
CTTCTTTATT |
TTTGTAAGAC |
TTCATTAAGA |
|
14481 |
GCAGTTTCAG |
ATTCTCAGCA |
AAATTGAGAG |
GCATGTACAG |
AGATTTCCCA |
TATATCCCCT |
GGTCCCACAC |
ATGCATAGCC |
|
14561 |
TCCTGTTATC |
AACACCCCCC |
ACTAGAATGG |
TACGTGTGTT |
GCAATTGACG |
AACCTGCATT |
GACACATCAT |
GATCACCCAA |
|
14641 |
AGTCCATAGT |
TTACATTAGG |
GTTCACTCTT |
GGTGGTGTAC |
ATTCTGTGCA |
TTTGGACAAG |
TGTATAATGG |
CATGTATCCA |
|
14721 |
TTATATATAG |
TATCATACAG |
AACATTTTCA |
CTGCCCTAAA |
AATTCTCTGT |
GCTCCATCTG |
TTCTTCCCTC |
CCTCTACCCC |
|
14801 |
TGACTCCTGG |
CAATCACTGA |
TCTGTTGACT |
GTCATCCTAG |
ATTTACCTTC |
AAAGCACACT |
TTTAATCACC |
TCAGAACATG |
|
14881 |
AGTCTTGAGG |
GAAGTGGTTT |
GGGGCTGATT |
CAGAGCACTG |
GAATGACCAC |
CTTGTGGTAC |
GCCTGGCCTT |
CTGATAGTCA |
|
14961 |
CAGGGTGACT |
GCCATGCTCC |
AGACATCTTA |
TCCTCACACA |
GCATTCAACA |
GGGAGGGCAG |
GAACTTTCTT |
CCCGAGTCTT |
|
15041 |
TGTTTTTCTT |
TTTACTAATG |
AGGTGGGACT |
TTCCTGGAAG |
ATCCCAGTAG |
ACTTCACAGC |
AGGTAAAGTA |
GTGCCCAAAC |
|
15121 |
TGACCCGTAT |
AGGGGAAGGG |
CTTGGATTGA |
TTCGAGTTCA |
TCTGCTGGGC |
CAGGCTGTTG |
TTGCTGTCGT |
TGCTCCTGGG |
|
15201 |
AAGTTGTTGT |
TTAATTAGGA |
AGGTGAGGGT |
GCCACACAGC |
CTTGCTTCCA |
GGTGGCCCCT |
CTGGGCATGT |
TTTTCTTAAA |
|
15281 |
ATAACAGACC |
AGAGAGAAGC |
TCTTTCTGGT |
TTTCAGTCTC |
CTTTGTGGCT |
CACAGGCCCT |
GCCACTCCGT |
GGTTCTGACC |
|
15361 |
TTGGGTGGGT |
TACTGAGCCT |
TGGAGTCGGT |
TTCCTTATTT |
CTGTTACAAG |
CAGTCTCACG |
AGGGTGGATG |
GAAAGGCTCC |
|
15441 |
CTGCCTGGCC |
AGGGAATGGA |
GAATCATAGC |
TGTTCATTGC |
CTGCTCTCAC |
CCTTACCTCT |
GAGGTTGGTT |
GGGTTGGGTT |
|
15521 |
CCATGTAAGA |
AGTGCAGCTT |
GAAGTGGGCT |
AAAGGCAGTG |
TGTTTATTGG |
GTATTGTGGA |
GCCTGGAGAC |
CTGTTTTTCT |
|
15601 |
CCCAGGTACT |
CATTTATAGA |
GAACTGTTCA |
AGTCCTGCCA |
TTAGTCATTT |
CTTTCATCAG |
GTGGTGACTG |
CATTCTGGTA |
|
15681 |
AACGAATGAG |
CTAAATGCAT |
ACCCCAGCTC |
ACCAGTTCTG |
GGGCACCAGT |
TCCTTGGAGC |
AGGTACCGGT |
CCCCACCCTC |
|
15761 |
CTGTCTACCT |
CTTAGTCCTC |
AGCTCCCAGC |
TCCAGGCTTC |
AGGCAGCATT |
GGTACCCATT |
CTGCCCCAGG |
ACATCCGTCT |
|
15841 |
CTACTCCTGC |
TCTATTAAGA |
TACCACCACC |
CAACCCCCAC |
CCGTTTCTTA |
CTTTGTTAAA |
GTCCACATAG |
TCCAGTAGCT |
|
15921 |
GTGATAACAC |
TGCCAATTCA |
TCTCTGCCTC |
CCCATCCTAC |
TTACAAATGT |
TGACACTGTT |
TTTTAGGTTG |
GGATTTTTGT |
|
16001 |
CAGGATTTTC |
TTTTTTTCCT |
AAACTCTTAC |
ACAACAGAAC |
TGTAATGTTT |
TTATGGATCT |
TCTGAGTAAT |
GAATGCTTAG |
|
16081 |
AACCATGGTG |
AGTGCCCACC |
CTCAGTCTTC |
CAGTAAAATC |
AGTTTTGTGT |
CCATTATATG |
TTAACCACTG |
GCTGACCCTC |
|
16161 |
CAATCTGGGA |
TCCTAATTAG |
AGAATTCTCA |
GGAACTCAGT |
GTCAGCTATC |
ACAATAGGCT |
GGCAGTGGCT |
TCCTGAGAAA |
|
16241 |
GCAATGCCGA |
TGGTGTTTTT |
GAAAAGGAAG |
TTGCAGATAT |
CTATTGCAGA |
TGTCTGTTCC |
TCTTTTCTCA |
TAGCGTCTCT |
|
16321 |
GGAGTTCCCC |
TTTTATTGGA |
AGGCGCCGTC |
GTGGCTTGTC |
CAGCTTCTGG |
GAAACTGGAA |
TAATAGAAAG |
AGCATGGTAT |
|
16401 |
TTGGGTTTAT |
AATTTATAAC |
GTAGTTTTAC |
TATTTTACTA |
AATTATAAAT |
TTACTATTTT |
TATAATAGTA |
AATTTTACTA |
|
16481 |
TTTACTATTT |
TCACTTCTCC |
CTGTCTGCCT |
CAGTTTCTTC |
ATCTGTGAAA |
TGGGGATAGT |
GCTGTGGAGA |
AAGAATTGCA |
|
16561 |
TTCGTTCATG |
TGTGGAAAGC |
ACCTAGCCCA |
TTTAGAGTAA |
CTCAGAGTGG |
AACCACTGGC |
CACAGAGTTG |
CTAGCAGTTG |
|
16641 |
GCTGGGTTTA |
CTGAGTTAAT |
TCTTGAAGGG |
CCACCACTGC |
AACCTCCTTA |
GTATTCCTGT |
TCTCTTCAGT |
CATCTCTGTT |
|
16721 |
ACAAAGTATT |
AGCTGTGCAA |
AAATGAGCAT |
GGGTTGTTTT |
GTGGGGCAGC |
ATTGGATAAA |
ATAAGTGGGA |
TGAATGCTGC |
|
16801 |
ACAAATTCTT |
TCTTTCATTT |
CTCTATTTCA |
GCCTAGGTTG |
GTTTTTACTT |
TCCCAGGAAA |
ATTATGACAA |
CTCAGGAACC |
|
16881 |
AGCCTACAAG |
GGGCCAGCTT |
TACGCCCCAG |
GTTCCCTGTT |
GGTGTGAGAC |
ACTTGGCACT |
AGAATGAGGG |
TGAAAGCTTG |
|
16961 |
CCTTATAGCT |
TCCTCTTACC |
ACATCCCATA |
GTGCTGACCC |
ACAGCCTGGA |
GAGCAGCAAT |
GTGTGTAGGT |
CACAATTAGT |
|
17041 |
GAACCACAGA |
GGAGCCCATG |
GGGGTGGCAG |
ATGGTGGAGG |
GGGATTTGCC |
TGCACTGAAC |
AATGGAGGAG |
CAATATATAC |
|
17121 |
ACACATTATA |
TGTGAAAGAT |
GATGGGGGAT |
TTTGGGAAGG |
AATATTGCTT |
CTTGCACTGT |
GTGTGACTTC |
TAGACATAGT |
|
17201 |
GTGCACCTCG |
AGGGACCACA |
GTTATTTTTA |
GCTGGGGAGA |
AAATCCACGG |
GGTGCTGGGA |
GAGTCAGGGC |
AGGAGGAAGT |
|
17281 |
TTATACTCCC |
CATCTCCAGA |
AGAAGGTGGA |
CTGCCGCTCA |
TCTCTGGTAC |
GCGGGGTCCT |
TTTGTAGTCG |
AGTTATTGCT |
|
17361 |
TGGAGTCAGG |
GAAGAGCATT |
CACAGGTCTG |
GAGTAGGACT |
GTCGCAACTC |
CTTAGATGTC |
CAGTGAGGTC |
ACAGGAAACC |
|
17441 |
CTCCCTAGAT |
ACTGCAGTTC |
CTGCCAGACT |
CTTCAGCACT |
GGCATCTCTG |
ATGAGTGCTC |
TGCTGCTGGT |
TTCTGACTTG |
|
17521 |
TCTTGTGTCA |
TTACTCTGCT |
GCTCATGTTA |
CAGTCGTCTT |
TTTCACAGGG |
ATGCTTGAAG |
ATGGAAAGAA |
ATTTGATTCC |
|
17601 |
TCCCGGGACA |
GAAACAAGCC |
CTTTAAGTTT |
ATGCTAGGCA |
AGCAGGAGGT |
GATCCGAGGC |
TGGGAAGAAG |
GGGTTGCCCA |
|
17681 |
GGTATGCTCT |
CTCATTTGTT |
TTGTTTTGCT |
TTCTAGTATT |
TACCTTTTAT |
ATTTTTTTAT |
AGGTGGCATA |
TTTATACGGT |
|
17761 |
TCAAAAATAA |
AAAAAGTGAA |
AAGTCTCACC |
CTCATGCCAT |
CCCATCTGAC |
CAATACCCCC |
ACAAGAAGCT |
CCTGTTGTTA |
|
17841 |
ATGTTTCTTG |
TACTGTGGTT |
TAAGCACATA |
TAAAAACATA |
ACTTTTTTCT |
TGCTTTCACA |
CACATACTGT |
TTTGCAGTTT |
|
17921 |
ACTTTTTCAC |
TTAATGCATT |
TTTGACACTT |
GCAATACCAC |
TACATAAAAG |
AGGAGTAGGC |
TGGGCGCGGT |
GGCTCATGCC |
|
18001 |
TGTAATTCCA |
GCACTTTGGG |
AGGCCAAGAT |
GGGTGGATCA |
CCTGAGGTCA |
GGAGTTCCTG |
TAATCCCAGC |
ACTTTGGGAG |
|
18081 |
GCCAAGATGG |
ATGGATCACC |
TGAGGTCCGG |
AGTTCGAGAC |
CAGCCTGGCC |
AACATGGCGA |
AACCCCATCT |
CCATTAAAAA |
|
18161 |
TACAAAAATT |
AGCCGGGCGT |
GGTGGCAGGT |
GCCTGTAATC |
CCAGCTACTT |
GGGAGGCCGA |
GGCAGGAGAA |
TCACTTGAAC |
|
18241 |
CCAGCAGGCG |
GAGGTTGTAG |
TGAGCCAAGA |
TTGTGCCATT |
GCGCTCCAGC |
CTGGATGACG |
AGAGCGAAAC |
TCCATTTCAA |
|
18321 |
AAAAGAAAGA |
AAAAATGAGG |
AGTAAGCTCT |
GTTACAGCTG |
CCTAGTATTC |
GTTTATGTAA |
GTGTGCTATA |
ATTTACTTGG |
|
18401 |
CTAGTGCCCT |
ATTAATGAGT |
ATTTGAGTCA |
TTTCCAGTAT |
TTTGCTATTA |
TAAACAATGC |
TGCAGTAACT |
CACCTTGTAC |
|
18481 |
AGACTTCATT |
TTCCACGTGT |
GCACATGTTG |
CCATAGGACT |
TACTCTCAGA |
AGTGGGATGA |
GGGGCTCAAA |
AGCTGTGTGT |
|
18561 |
AGTGTTTTTG |
AGAGGTCTTG |
TCAAGTTACC |
ATCTCTAGGG |
GTTGCACTCT |
GGACTGCCAC |
CACCAGGCTA |
TAAAGGTGCA |
|
18641 |
ATCTCCTCCC |
AGCCCCAGCA |
TCACAGTATA |
TTGTTAAATC |
TTTGGCCTCT |
GGACAATAAG |
AGTAAAACAT |
GATATCAGTG |
|
18721 |
GTTTTAATTT |
GTATTTATCT |
ATTACCCATA |
TTGTGTGAGA |
CCACTTCTGA |
GACGTCATAC |
TTATGGAGAA |
AGTCATTTCG |
|
18801 |
TTTGTCTTGA |
GTGTGTTTCC |
TAATCTCTTT |
CCTCCCCATT |
TGTGGAAACA |
GCTTTTGTTC |
TGCCAACACT |
ACAAAATTCC |
|
18881 |
CAGGAGACAA |
TAGGGACCCA |
GGGTTGCCAA |
ATTTTAGTTG |
GATTCTGTCT |
TTCCATCAAA |
CCTAGGAATT |
TTTTCTTGGC |
|
18961 |
TCTAACCAGG |
TAAAGGGATG |
TTTTTCAGTG |
ACCTGAGACC |
CAAGGAACTT |
TATAATTAGG |
CTCTGCATGA |
TGGGTAATTA |
|
19041 |
GTCTGCTTCC |
CTCTCACCCA |
GGAGAATTAG |
AAATTTAACC |
AAGATGAAAA |
GACAGATTTC |
TGTCTCTCTC |
TTTTCCAGAA |
|
19121 |
TACACATTGC |
TCTACTTCCT |
CTATAAAATA |
TCACTGATTT |
ATCTCCAAAT |
AAACTGCTCA |
ACTTTCAGGA |
ACTTGAAGCC |
|
19201 |
ATCCCACTCC |
CAGGTGTCTG |
GGTTTCTGTT |
CCTGCAGGGC |
AGAGGGTTGG |
CAGTGTGAGG |
AAGAGGCTTT |
GTAGTTTACT |
|
19281 |
TCCCTTGGGA |
AACCTTGCCA |
ACCATAGCTT |
TTTGCCTCTG |
TCTCCCTAGT |
CTGTCTGGCT |
CTTGGATCTG |
TAGCCCATCC |
|
19361 |
CCCATCTTTC |
ATGCCAGCCA |
TTGTTCATAC |
CACAACCCAT |
CTTCTGTGAC |
TGCTCCAGCA |
TTGGAACAAT |
CACTGCGTTG |
|
19441 |
TATGTACTGA |
GTGCTGTATC |
TGCCATCGAG |
ATAGTGTTAT |
CGGCCTACTT |
CACTTCCCAG |
GCTTGGAGAG |
GCATGGTCGA |
|
19521 |
GTATTGGACA |
GATGCCTGAC |
TCCCCCTTTA |
ACTGGTATTT |
TGGGGTCAGT |
CACAGCCCTG |
TCATTTGTGA |
GAAGTCTGGG |
|
19601 |
TAGTTTGAGA |
TCTACATAAA |
ATATCTTTTA |
AATTCTTCAT |
AGCATATTTT |
TTCACCAAGT |
GAGTTAAAAA |
CACAGGAAGA |
|
19681 |
AGGGGAGATT |
GACTTGTGAC |
CCTTTTCCTT |
TCCTTTTGAT |
ATTGTTTTGG |
TTTTACATGT |
TTGCAGGCGT |
GGAGTCCTGC |
|
19761 |
CTGCCACAAG |
GACCATTTTG |
GCAGCTTTCT |
TTCATCCATC |
TTGGACATCT |
TTTCATGTTA |
ATACATTTAA |
AGCCACCACT |
|
19841 |
ATATGATTTC |
TCATGACTAA |
TCCCTGGTGT |
GGATATGCCT |
ATGAAACCAC |
TCCTTCTGTG |
ATGGACTTTT |
GAGTTGTTAG |
|
19921 |
CAGAATATTC |
TGGAAATAGA |
ATTGCTGAGT |
CAAGGAATAT |
GATTGTTTTG |
AATTGTACAA |
GGTAAAGCCA |
TACCTCACTA |
|
20001 |
TCCTTACCAC |
CTTGGTCCAA |
CATGTCCCAG |
CTTCTGAGGG |
GAGCAAGGAC |
TAGACGCTTC |
ACAGCCTGGA |
GCTTCCTCTT |
|
20081 |
TATTCATCCT |
CTGTCTGGTG |
GAGTTGGAAA |
GTCGGGAACA |
TACACATGGA |
GACCAAAAGC |
AGAGATAAGT |
CAAAGGATGG |
|
20161 |
AAATACTGCA |
GAGAACCTGC |
TCACTGTTCA |
GAAAGTAGAT |
ATTTTATACT |
TATTTGTGTA |
TTTAATTTGA |
AACTGAAAAT |
|
20241 |
ATACACAAAT |
ATATTTTTTA |
AAGTAGAAAT |
CTCTCCTTAC |
TGGTCACTCA |
CTATCCATAC |
TGTTCTCCTC |
ACAGCAAATG |
|
20321 |
TCTGGTATGT |
CCTTCCAAAG |
ATGTTTTCTG |
TTGTAGGCAT |
ATCAATATTT |
TCACAAATGG |
TATTCAGTAA |
ATGCTATTTT |
|
20401 |
GTAGCCCAGA |
AAATCATATT |
GTCTTTTTTG |
AAGTTTTCCT |
ATATGGGTAA |
AAGAGTATAA |
ATAGAAAAAA |
TACAGAAAAA |
|
20481 |
ATAGACTACC |
CTCAAGTATT |
ACTTCCTGTG |
TATATATTTT |
TTTAAAGCAA |
AGTTGAGTAT |
TCCTTTTTCA |
AGAAGAGCAT |
|
20561 |
AGATGGCACT |
TAACATGTCC |
TTTAAGTGAC |
AGATCACTGA |
AGGGGACTAG |
GTGGTGAGAC |
ATCTGGAATG |
TTACCTGCCT |
|
20641 |
AGCATTAGTC |
ATTAAGACTT |
GCGTAGAAAG |
GTTGAGGGCC |
TGACCGTTCT |
GAGAGTCAGG |
AGGGGTTTTG |
AACTGCCATT |
|
20721 |
GGGCTTCTTG |
GAGTGAGATG |
CAGGGGTGAT |
GGAATATGAC |
TGCCAACCTC |
CAAGTCCTGC |
ACAAGGAGGT |
GGTGATGCCT |
|
20801 |
GGGCAGCTGC |
AAAGTCACTG |
GAAAGTCAAT |
ACCATCCTGG |
CCAAGGAACA |
CCTAGGTAAA |
CAGCTCTTTT |
TCTTACAGAG |
|
20881 |
ACAGTTGGGG |
CATGTGTCCA |
GCTGAGTCTG |
TCTTCCTTGT |
TCTTTTCACA |
GATGAGTGTG |
GGTCAGAGAG |
CCAAACTGAC |
|
20961 |
TATATCTCCA |
GATTATGCCT |
ATGGTGCCAC |
TGGGCACCCA |
GGCATCATCC |
CACCACATGC |
CACTCTCGTC |
TTCGATGTGG |
|
21041 |
AGCTTCTAAA |
ACTGGAATGA |
CAGGAATGGC |
CTCCTCCCTT |
AGCTCCCTGT |
TCTTGGGTAA |
GGAAATGGAA |
TACTGAAGGG |
|
21121 |
CCCTTCACTG |
CCTTTGCTCC |
TCCCATGTTA |
TGCCCAGCGT |
TTGATGGGTA |
GCAGAGAGAA |
CAAAAAACAC |
CACAAGGCTA |
|
21201 |
TTTTTCCCCC |
TGCATTCTTT |
CTGTATTGAG |
TATCCTTTCA |
GTGTTATTAG |
TGTATGCTTT |
GAATGTAAAA |
ATTGGTCACC |
|
21281 |
CTAAGGAAAG |
GAATTGGCAT |
GTGTATGTTC |
CCAGTTCAAC |
TCATGGAGAT |
GGCAGCTGTT |
TAAATGTTTT |
TCTATGTAGT |
|
21361 |
TTATAAATTA |
AAACTGAATT |
GAGGACTATG |
GAAATGTAGG |
CCAAATTTGT |
AGTGCCAACA |
TTTTAGTTCT |
TTGGAAATAA |
|
21441 |
GACTCTTAAT |
GAATGACTTT |
GTTCTACCCT |
GTGTTTCTAG |
AAGCTAGAGG |
GGGAAAAAAA |
AAGCCCTTTG |
GATATGAATA |
|
21521 |
TCATGTCCTA |
GCTTCTGCGG |
CTCTCTCTTC |
ACTGTGGTTT |
GTGGTTACTG |
CCTATTAGAT |
GGTATGAGGG |
AGGCATTCCT |
|
21601 |
GCATCGGTCC |
ACCTGCTCAG |
GGTCCACACC |
CAGGACACTT |
GAGGCCCCCA |
GGCCAGCTTA |
TCAGTGAGTG |
AAGTGGAAAA |
|
21681 |
ATGAAGCCAG |
AGGATGCTTG |
TGAAGTTGAA |
AGGATGCTCT |
TAGATCAGAC |
AGTTCTAGGA |
AGGGATCTTA |
GGGGCCTCTG |
|
21761 |
CATCAGCTTT |
ATTGTGCAAC |
AGTAAGGAAA |
CAGGGCCAGA |
GAGAAAGGCC |
TTACTCAAGG |
TCACATCCAG |
GCAGTGGCAA |
|
21841 |
AGTAGGACCA |
GAGCCCCTGT |
TTGTTGATTT |
TCCCCTCTTC |
CACCCTCATT |
TCTTAGGAAC |
TAAACTCAGT |
ATCCTAGTAG |
|
21921 |
CACGTAACTT |
TTCATGTAAG |
TGTTAGAATC |
ATTAAGTACA |
TGAATGCTAC |
TGGCTTCCTT |
CCAACTGGCC |
CCAGACCTTT |
|
22001 |
TTATTTGCTC |
CCCTCCTGCC |
ATAGGAACCA |
GAGGGTCACA |
GCCAAGGCCT |
GGGTGAGGAC |
ACTTTTGTTT |
GAAAGCCACA |
|
22081 |
ACAAATGGCT |
GCCATCCTAT |
TTGTGATGGC |
AGTCAGAGCT |
ACTTGTAACC |
TGGTCCTGTT |
GTGCACATCT |
GTAAGTGGAG |
|
22161 |
GGGCTTTTTA |
AACTCTCTGT |
TTGAACCACA |
CACACCTTGG |
TAATACAGGC |
CTGGTTAAGT |
TTGATAACTG |
GTTTCTTCAC |
|
22241 |
CTGTCATTGC |
TACTGGGAGG |
GAATCCCTGG |
CACTTTACAG |
GGCCTTTGTC |
TGCCCAGAGG |
TCTGCACCTA |
GGCCAAAATC |
|
22321 |
CCTTTCCTGT |
TCTTTGAGAG |
CTGAGTCATT |
TTTTGAACAT |
AACTGTACTC |
GAGGGAGCCT |
TGGAATTATT |
TTCCTGGTTG |
|
22401 |
GGAACAGGCT |
TTCTGTAAAC |
TTGATGAGGT |
AGAGGGAGGG |
GAGAGAGGGA |
TAAAGGCTAC |
AAGTCACCCC |
GAGTAACCCT |
|
22481 |
CCCAACCCAC |
TGCCAAAGAA |
TGTCTCAGCT |
TCTTGCAAGA |
GTCTGGAAGG |
AAAATCCAAG |
GGCAAACCCA |
GAAAGTTTTA |
|
22561 |
AGTTGAGTGA |
ATGAATGAAT |
ACTGGAGATA |
TTTTCCCAGT |
ATACTCAACA |
TTATGAATGA |
CCAGTTTATT |
CTCAGTCTGG |
|
22641 |
ACTGCACATG |
AGAGTCACCT |
GGGAAATTTT |
TAAGACTTTC |
CTGATGCCCA |
GGTCAAACCC |
TAAACCAGTT |
AATCATAATC |
|
22721 |
ATGGGAGTGG |
AACCCAGGCA |
TTAAGAGTTT |
TTTAAAGCCC |
CCAGGTGATG |
CCTATATGTA |
GCACAGTTTG |
AGACCCAATG |
|
22801 |
ATAGTGGGGA |
ACTGTATTGT |
CAGCAGCATG |
GGTGGCTAGC |
CCTCCTGCTG |
TCCTCAGCAA |
GGCAAACTTA |
ACCTTAGATT |
|
22881 |
AAACAAAACA |
CACAGATCAA |
TTTAAGGAGA |
AAGTTTGTTT |
CACCTGGGAC |
CCAGCCCAAG |
TCTTTCTGGC |
TGTCTCCAGC |
|
22961 |
TGGAACAGAA |
GTGGCTTGGT |
CTCAGACTGC |
TCAGCTGTTG |
GGGAAGGGAT |
TTGGCGTGGC |
AGATGGCATC |
GTGGCTGTCG |
|
23041 |
CCACTGCACA |
CAAAGAACAC |
TGAGTTGCTG |
GAAACTCACA |
GATTTTCTGT |
CCCCAACAGA |
TCTGCCATGG |
AGGGATCTGG |
|
23121 |
TGCCTCCAGA |
CATGTGCACA |
TGAATCCATA |
TGGAGCTTTT |
CCTGATGTTC |
CACTCCACTT |
TGTATAGACA |
TCTGCCCTGA |
|
23201 |
CTGAATGTGT |
TCTGTCACTC |
AGCTTTGCTT |
CCGACACCTC |
TGTTTCCTCT |
TCCCCTTTCT |
CCTCGTATGT |
GTGTTTACCT |
|
23281 |
AAACTATATG |
CCATAAACCT |
CAAGTTATTC |
ATTTTATTTT |
GTTTTCATTT |
TGGGGTGAAG |
ATTCAGTTTC |
AGTCTTTTGG |
|
23361 |
ATATAGGTTT |
CCAATTAAGT |
ACATGGTCAA |
GTATTAACAG |
CACAAGTGGT |
AGGTTAACAT |
TAGAATAGGA |
ATTGGTGTTG |
|
23441 |
GGGGGGGGGT |
TTGCAAGAAT |
ATTTTATTTT |
AATTTTTTGG |
ATGAAATTTT |
TATCTATTAT |
ATATTAAACA |
TTCTTGCTGC |
|
23521 |
TGCGCTGCAA |
AGCCATAGCA |
GATTTGAGGC |
GCTGTTGAGG |
ACTGAATTAC |
TCTCCAAGTT |
GAGAGATGTC |
TTTGGGTTAA |
|
23601 |
ATTAAAAGCC |
CTACCTAAAA |
CTGAGGTGGG |
GATGGGGAGA |
GCCTTTGCCT |
CCACCATTCC |
CACCCACCCT |
CCCCTTAAAC |
|
23681 |
CCTCTGCCTT |
TGAAAGTAGA |
TCATGTTCAC |
TGCAATGCTG |
GACACTACAG |
GTATCTGTCC |
CTGGGCCAGC |
AGGGACCTCT |
|
23761 |
GAAGCCTTCT |
TTGTGGCCTT |
TTTTTTTTTT |
CATCCTGTGG |
TTTTTCTAAT |
GGACTTTCAG |
GAATTTTGTA |
ATCTCATAAC |
|
23841 |
TTTCCAAGCT |
CCACCACTTC |
CTAAATCTTA |
AGAACTTTAA |
TTGACAGTTT |
CAATTGAAGG |
TGCTGTTTGT |
AGACTTAACA |
|
23921 |
CCCAGTGAAA |
GCCCAGCCAT |
CATGACAAAT |
CCTTGAATGT |
TCTCTTAAGA |
AAATGATGCT |
GGTCATCGCA |
GCTTCAGCAT |
|
24001 |
CTCCTGTTTT |
TTGATGCTTG |
GCTCCCTCTG |
CTGATCTCAG |
TTTCCTGGCT |
TTTCCTCCCT |
CAGCCCCTTC |
TCACCCCTTT |
|
24081 |
GCTGTCCTGT |
GTAGTGATTT |
GGTGAGAAAT |
CGTTGCTGCA |
CCCTTCCCCC |
AGCACCATTT |
ATGAGTCTCA |
AGTTTTATTA |
|
24161 |
TTGCAATAAA |
AGTGCTTTAT |
GCCGGCTTTT |
CTCAG |
|
|
|
|
|
|
|
|
|
|
|
|
>ref|Gene_ID:2280|FKBP1A|NC_000020.10:1349621...1373815 (-)
TTCCGGGACGTCGCGCGCCGTGTGGGGCGCGCACGCAGGGCTGGGCGTGAGGGGGCGTGCGCGTGCGCAGGCGACGCGCC
GAGGTACTAGGCAGAGCCGTGGAACCGCCGCCAGGTCGCTGTTGGTCCACGCCGCCCGTCGCGCCGCCCGCCCGCTCAGC
GTCCGCCGCCGCCATGGGAGTGCAGGTGGAAACCATCTCCCCAGGAGACGGTGAGTAGTGGCGCGCGGCGGCTCGGAGTA
CCTCTGCCGCCGCGCGCATCGGCTCAGCATGCCCGTCTCTGTCTCCTCAGGGCGCACCTTCCCCAAGCGCGGCCAGACCT
GCGTGGTGCACTACACCGGTGAGTCGGGGGCCCAGCGGGGAGGGGGCCCGGGCCGCAGTCCGCAGCCCGGGTGCGGCTGG
CCGTCGAGGCCTGGGGGCCCGGGGCCTGGGGTCCGGGGCGTGGCGGCGGCGAGGTCCGCATGGCCCGAGGCTGAGGCCTG
GGCGGTGGCTCAGGGGCAGCCTGGGGCTTGCGGAACCCGGGCGGGTCTGAATCGGCGGCTGTGAGCGTCGGCTGCGGGCT
AGGTGTTATCTGACCCGTCAGAAGCATTTCTGCACCTTAGATGCTGCCCTTATGCCCGCTGCACAGATGAGGAAACTGAG
GCTTGGCGAGGCGAAGTCACTTTCCCAAGGTCTCACTTTCCCAAGGTCACACTTTCAGGAATGGGCAGAGCTCTGGCCAG
GGACCATTAGGAAGGATTTGTACCATTTCTGTGCCCCTGCCCCCACTTCCATCCCTCCCTTCACTGGAGATGAGGACGAG
GTAATTCCGAGTCTGCAGAGCTGCTGCTTCCTCCGGGGAACTCGGAATTCGCCCCTTTGCCTAGGGTGGGGAAACATCCC
ACTTCCTAAGTCATTGCTTTGGCCCTTCCTGGCCTTGGGGGAAGTAGAGCTGCACGGCCTTCTTCCGTCTTTTTACTTTT
GAGCCACTTACAAATCCAAGGCTCAGTGACAGCGCTGGCTCAGGCTGACCGAAAGCTGCACGTGTAATTTAGTCCCCCAG
CTCTTCTAGAAGTAGAGACTTTTCTCGTCCTCATTTTAAAGATAAGCATCTGGAGGCTAATACATAGTGATAATACAAGC
CAAAGGAAATTTTAGACACCTCCCCCTCCCCAGCCAGAATTCAGACATCAGAGTCGTGTGCCTTGGGGCTGTCTTACTCC
TTCTCCTTACAAGCTTGTCCTGGTTTGTATGGGGGCGGGGGAGGGGGAGAGCTGAGTTGGCGGAGACTCAGTGGCTGTGG
GTCCCACAAGGGTGGCAGTGATTGGTGTAGCCACAGTTGTTGATACGAATAACCTTCCCTCCCCCTCCTCCTTCCCCTTT
CTCAACCTTCCCACCCTTTCCTCTGTTCCCCCTCCTCCTCCCTCTTTTTTTCCCACTCCCTCTCCTCCTCTTCCTCCTCC
TGGGTAGTAGGCTGTGGGCAGTTCTGGCCAAGTTGCTCACGAATAAGCTCCACCTTTCTCTTCCAAATCATGGAAACATG
GAGGGATCCCTCTATTGAGGGAAATGACTTTCACTGGAAAGAGGAAAAGGCAACTAACATCCCCCCTCCCATGCCCTTTT
ATTTCTGTGGCCCTTCCCCGTGGGTAGAAATGGGGGCAGGAGGTAGAAGTTAAGGACTAGAACTTTAAAAATTCTGCCAA
AGGAGGAGTTACTGAAACCCATCTTTCTGGGGAGCAGGCAGTCTCATGTCCGTGAAGGAAGCTGGAAAGTGCTTTTGATG
TTTTAGATAGCTGTCCTTGTAGGCCACAGTCAGCACCTGAGCCTGGGAGGTCTGGTAGATGAAAGCGCATCCTTTTGGTG
ATTTGTCATCGGAAGGATGAGGAGAGTAACCATTTACAGTGCTGGGGTGAGTGGGCAGTTCATTCAGTTCCGCAGCCAAC
TGGGGCAAAGATTGGGACTCAAGCCGTGAGGAGCTGCCTTCTGCCGCACCCCCTCCCCACCCTAGCTTGTACATAGCCAC
ACTAGGGTGCTTGGCAGCATGTGTCCCACTCCCACGTCTGCCCCTCATGCTCGCCCATGTTCTGGTGCTGCCAACAGGAC
TGGACCCCAGCATGTAGGCAGTGCCGCACTTCACCATGTCTCTTTGTGAAATATCCCCACACAGCATGTCTGGAGCCTTT
TCCTATGAGAACAGATGGTCATGAGACCCAGAACACCATCAGGGTTTCCAGTGCCTCTTGAAGTGTGTGTTTTTCTCGCG
GGTGGCACGCACCCACATGTTTCCAGAGCAGCAGCAGGACCCTGGCATGCATTAGGACAAAAGCTTTCTTTTTGATTTCG
TTTTGATAAGCCCTATAAAGACGCCTTAGTGAGAAGCCAGCTCTGCCTCATGCTCACAGAATAGACTGTTTTCGAGCAGG
CTGGTGGCTTTGTTCCCGTGGGTCTTTGTCACCAGCCTCCCAGGAATAACCTGTTTGAGACCTGTGGGGGCGTGAGAGGA
GTGGGTAGGCACTGGGAGATCTCATCTGTAGCAGTTAAGGCTTTTAAGTCACTGGGAACAGAATCCATCTTGGGGGAACA
TGATCAGAAGGTGGAGGTTATAAAGGTTCCAGGGGTTTTCAAAGGCAGAAGCCCACTGGGTCCTAAGAAGGGAAAAGAAA
TAATCATGATGCCTCTAGTTCTCATCTCTGTTTTTTGGTTGTTGTTTTGTGTTTTGTTTTGTTTCCTGCCTGACTGCCTC
AGTAGTCTCCTGTTAGAGATTTGTGTTTGTCTGCTTCTCCCAACTGGTGGGTGGTGGAAGTCCCCTGCATGCTCCCCCGT
CCCCCCTCCCCCCTCCCCCCTCCCCATGGCCAGCTTCTCTGTCTTCTTTTGAGTATCTGGCTCAGATTTCTTGGCTGTGA
TTCTGATTGTTACTTCTCTGAGAAGGAGAGTTTGAGTAAGGTGAACACTCTTGATCCAGTCAGCTCTTGCCAGGTGTCCA
CTCAGCTGATTTGGGCACGGGTCCAGAGAAAGAGGCGTGGAAGTAAGGTGGCCAAAATCTCCCCTTAGCCATCACAGGTG
TGCAGAGCACAGACTGACCTTTACCACATGGATGCTTTAAATGCCACTAATGGCTGTCAGTCACCTTGATGTCACTCTCA
AGGGTCCCTCTGGTGACTTCCGTGACCTTCTGGCAGAGCACAGCATGAGCAAGGCCTCAAAGGAATGCCTGCACTACCTC
TGTGGTACCAGAGGGAAAATACAAAGTTCACTATCACCAGCTAAGCATCTCCTAGGAGCATGACAGGCATTGAGGTGGGA
GGGAGGTGGTGGAAAGGTAAGCTGCCAAGTAAGTGCCTTTAGGAGCCAGGGAATTCTCATGGCGCCTCCCTGCTGCCTCC
AGTAGCTTCGTCATCTTTACTGTTAGCTTGTCCTGGCACACAGCTAGGTTTAGACCTCTTTTACTTACTTCAGCAGGCCG
TGTGCCTGCCATTGTGAGAGCAGCCCCAAGGGGATTGAAGGAATGTTTTCTTTTTTCTTCTTAAAAAGTAACTAACTGGA
CATTTTGTCCTTGGGATCAGGTTTAAGTCAGGTATAGCCTCCCGGTTTCTGACTGAGAAAAACCAGGAGCCCCTCAACCT
CATGTCCTCAGGAGGTTGACTGGGAAGGCTGCTGAGGCTCCCGGGACAGGTGTGGCCACTTTGCTGCAGCCTCCCTCAAG
CCCCTTGCTTTTCCTTAGCTTTGTTCCCCCCTCTCCTCTGCTTTATTCCATCCACTCCCTTGCTAGGTATCTCTTGGTTG
GTGATCTGATGTCTGGAGGGAGGCTCACCCTCAGCAGAGATGCCTCAGATGGCTTCCCCTGACGTGTGCTGTCTTGAGGC
ACACAGGCTGTAACTGTTGGGCAGGGCTGCAACAAGTCCCTTTGCCTTCCCACAGCAGATGTTTTTTGAGCAACAGCAGC
AAGCCAGGCTCTAGGGACATGGCTAGTGAACTAAATAGACAAAGACCTGATCTGGTGGGGCTTTGCTTATGATGAGGAGA
CTGATAGTATGGCCATGGAGCACATCAGGTAGTAAGAAGCGCTGGAGAGATTAAAGCAGAGTGAGGGATGGGAAGGGAAG
TTGGCTGCTTTTCGTGAGGGTGATTGGAAAAGGCCTCTGAAAAAAATGGCATTTTAACATTCACTCAAAGGACATTGGAG
AGGGAGCTACAGGGCTGTCTAGAGTATCCAGGCAGAGGGAAGAGCTAGTGCAGGACCCTGAGGCTGGAGCCTGCTCGGTG
CATTAGAGGAACAGTAAGAAGACCGGTGCGTTAGAGGAACAGGAAGTGGATTGTGTGAAAGGGTATGTGGCAGGAGATGA
GGGGATGGTGGAGCCTCGTTGGTTTTTATAAAAACGTTGCCTTTTTCTAACTCAGGTGAGAGCCACTGGCTGGCTTGGCT
TTTAATGCCCGCCCCCGCCCCCCCAACCCACGCTCCTTCTGGCTACTGTGTGGACAATGGGCTTTTGGGGGCAAAGGCAG
AAACAGGACACTGGTTGTATCCCAGGTGTGTGGAGTGCCAGCTCAGGCAGTGGGCAGAAGTGGTGCCAGGTGGACAGTGA
TCCCCAAAGAGCATGTGGGTTCTTCGCTGTGTTCTGATCTTGACCCTGCCATACAACGGGCTATGAGAGCTTGAACAAAT
TGTCCCACAGTTCCCAGCTTCCACATGCTGTCTATAAAATGGGAGTAACGATGCCTGCTGTGAAGCAAATGCCTATCGAG
ACTACCCAGTTGTCTCCAAAGTGTTGCTCTTTTTTAAAACCACAGTTCCATTGAGCCTCACTCATCGCAGTTGTTATGTC
TGTAATCTCAGTCTAGAAGAGTCCTTACGCTGTTTTTTTCTTAATAACTCTGATTTCTTCAAAGAGAGCAGGCTAGTTAT
AGAATACTCCACATCTGTCTTACTGTTTTCTCATGGTATTGTTTAACTTGTTCCCTGCCTTGATTTTCTGAACCGGATGT
TTAATCTTTTAAGTGTCTGAATAGATTCCGTTTAAACATTTTAGTGTGAGTACTTCATCCTCAGCACACATGGGAAACAT
CACTAGTTGTGATGCTAAATTTGATCTTTTCTGTAAAGGTACATTTTTCCCTTTGCATTTAGCAGTGATCTGTGGAGTGC
TTAGGTAGCCATAGATGGTCTCTTGCTCATCAGCCTTTCACCTAGTGGTGTTTACACCATCTGATCATTCTCCCCTGAAG
AAGTCACTGGCATTCACAAAGTGTTGATTTTTAAAATTCCTTCATTCTTTCTAAATTTATTAGCTGTTATCCTTCTATAA
GATAAGGTAAAGTAATTCTTTACCTTTAAATACCAAATTTTATTTTTATTTTTTGAGACAGTGTCTCTGTCACTCAGGCT
GGAGTGCAGTGGCTTGATCATGGCTCACTGTAGCCTCGACCTCCCAGACTCCCATCCCGGCCTCCCATCCGGCCTTCTGA
ATAGTTGGGCATACAGGTGCATGCCACCTGTCCTAATTTTTGTATTTTTTGTAGAGACGGGTTTCGCCAGGTTTCCCAGG
CTAGTCTCAAACTCCTGGCCTCAAGTGATCCACCCTCCTTAGCCTCCCAAAGTGCTGGTAGTACAGGCATGAGCCACCGT
GCCCAGCCTTTAATTACCAATTTTTAAAATGAAAAATGAATGTTAACTGATGGGGTATTGCCATTCCCAGTGGGGGCAAG
TGACTTTTTCCCCCTCTATTTGCTTTGACTGTACTGTGGGCTGAAATTTTTTGTCAGGGCCTTAAGATCAATGATACCCA
TTATTCTTTTTGATGCTAATATCATCCTAAATTTGGCCAGTAGGAGCCCTTTAAGCTGGCTCCAGTACCTTTTTGACAGG
CTCCCACCATTCCTTCATCCATTTCTCGGTTTCACTACTCTGGTCCAATTATCAGCCATCTTTCAAAGAGCTCTGGTTCC
TTTCAGTGGGGTCCATGACCTTTTTTTTTCTTGGTAACAGCTTTATTGAATATAATTTACATACCATAAATTCACCTATT
TACTCATAGATGTTTTAACTAGAACATTTTTAGGCTTAAACTGATTTTTATGAATTACTGAGGGGTTTATTGTATCCATA
AACTGGAAATCATTTGTCTGCCTTGGAATTTTCTCTAAAAATATTGTCACCTGCTGTTTCCCATGGAAGAAGCCAAGGTT
ATGAATAACTTAATCACATAGCATTCAGTTCTCCCTTTGGTGCTCATGGTGACATTTGTTTATTTTTACTTCTATTTTTT
CTTCTGTTTTTTTGTTTTCTTTTCCTGCTAAAAAGCTTAACCAAGTCTCTGCATTCCCTCCCCTGGACCCCTTTGATTTT
GACCAGGTGTATTCTAGCAGTGCAGAAAGTCGGGGAGGTAGAAATAACCAGTTCTTAGATGCTACTGTCTCTTTCTGTTA
CATTTGCTCTTCCTCTCCCAGGAGCTCAAGCCACCTTGGCCTGCATTCATTCCTCGAATGCTCCAAGCCTTTTCCCACAT
GGAGGTCTCTGCCCCTTTGCTTAGGTGCCACCACACTGCCCCCACTCCCCACTGCATGACAGGCTCTTTTCTTTATAGCA
CAGCTTAAGTAACACTTTGGATGCATACATGCATGCTTCTAATTCTGCAACAATGCACCCATCTATTTTCTTAGCCCCCA
TCATAGTCAGGATCCGTGTAGTTAAACATCTGCTCTTTCCCCAACCGACTGAAGGCTCCAGGAGGCCAGACCCACACTAG
TGTTGTTCTCCAAGGTCTCCCCATCAGTCTTGGCATAGAGTAGCTATTCAGTGACTGTTTGAATGAGTGGCCAGTTAGGA
CCTGGCATTCCCTCGGTCACTCAGTGAATATATAAGGAGCTGGGCAAAGCCTCAATGTTGCCCTCAAGAAGCTTACCCTG
TAGGGAGTGGTCAGTTACAATGAAAGTACCTCAGGCAACCTACACCTATAGGCTAGAACTTCTTGGAGGAAGTGCCATTT
GGTCTTGGGTGTGTATGGTGCAGTCAGGCAGGAGGAAAGCGTCTTCCAGGTATATACACAGGCCAGGAGGAGAAAAGGGT
ACCTTTGATATTTCTGTAAGTACTTGATGAATGTCTGCTATGTACAAGACACTGTCCTGGCTACCAAGAATTTAGGAGTG
AAGAAGACACAGTTCCTGCCTTCATCTCACACTGTAGTGGAAAAGACATAATAAATATGATTAATAAGCAAGACTGTTGT
GTATAAGCTAGTAAGTGTTAAGGAGGGAATAGGAAAAGGTTGAGGTTTTAGATAGATTGGCAAAGGCCTCAATGAGAAAG
TGACATTTGAGCAAAGACTTGAAGGAGGTAAGGATGTAACCTATGTGACTGTTTGAGCAAGATCATTTTAGGCAGAGAGA
ACAGCAAATGCAAAGGCCCACGGGTGGAGGTATCCCTGGTGTGTATGTAGAACATAAGGAAACAATGTTCTGGGACTGGA
AAAGTACAAGAGTAATCAGAGGTGAAGTCAGAGGGATGGTGGTAGGGGCGGAGGCTTGACACTTCTTAGAGGGTCTTGTA
GGCCATTTTAAGAGTTTTATCTCCTGAGATGGGGGAGTCACAGGAGTTTTTCAGCCGAGGGGTAGTAGGGTCTGGCTGCT
GTGTCAGGTTTAGACTGTAGGAGAGCAAGAGCAGAAGCAGGGAGACCAGGGAGGGAGTTGTAATAATAGTCTGTAACAGA
GGTCCAGAACTCATGCCTTTAACCATTATACCCTATAGAAAATGCATATTTCTACCACTTCCAGCTAGCTATTGTTAAGT
GGTATTTCTTTTGATTTTTTTGGAGATGGAGTCTCACTCTGTCGCCCAGGCTGGAGTGCCCTGGTGCAATCTCGGCTCAC
TGCAACCTCTGCCTCCCGGGTTCAAGCAGTTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGCGCACGCCACCA
TGCCCGGCTGATTTTTTGTATTTTAGTAGATACAGGGTTTCACCATGTTGCCCAGGCTGGTCTCAAACTCCGAAGCTCAG
GCAGTCCACCTGCCTCAGCCTCCCAAAGTGCTAGGATTACAGGCGTGAGCCACTGCACCCGGCCTAGTGGTATTTCTTTC
TCCCCCTCCCCATGCGATATAATGTGGTAGTAACTCCTCTTATTTATACTGTGATTAAAGTGGAAAATGGAGAGACACAC
CCACAGGGCATGCATTCTGGTCTGTGTTCTTTTTATTGCCGTTGGATCCTGCATATTCTTCCCATCATGGGCCCTGCCTT
TGAAAATACACTTTTGGTTATAGGATCTAAAGGGATTTAGCCAAAGGTTAGAAGCATTTCCATACTGCGTATGGGAAATG
TGCTTGCACTGTTGGTGATCTCAGGAAAATGATAGTGAGAGTGAGCTGGTTCCCTCTTTGGGTTGGCACTTGGACCTTTG
GTCATACCCCTCACTCATAAGGAGTTCTCAGAACCCCACTTCAGGGAGGTTGTGCTGGAATACAGCCACAGAGACCCAGA
AATGGAATAATAAGAATGTAAGATTTGAATTTGTATCTTTTGCCTATCTAAATGTAGAATCCCTTTTTACCCATCATGAT
TGAGACAAGTGGGTAGTTGGTATGCTAACATAAAAGTGACATGGCTTCTGTAAACATTTGATTTCAAACTCTAACATAAA
TCATTTGCTAAAGGACTATGTCTTTATCTTTGAGGATGGCTCTGCTAGTGGAGTTTCCCATCATAGTTCTTGCAAAAACC
AATTTGACCTTTTTTAAAGTAGAGCAAAGAGTATTGTGAGAACATTTAAAAACCAAACCTTTCCAGATTTTTAAGATTTC
TTTCTCTAAATGTAGTCTCCCATATGATTATTCACTAGCAATAGTTTTTTAGTGACTTGCCTTTATTGAGTCTTTCCCAG
GAGTCAGCTAGAACCGCTGTTTGTATTCACACTCATTTTATTGATTTACATACTATTTAATTACATTATATTTACACAGT
AAATATAGCTACCATAAATGGATTTGGGGACAAACACAGCTAACCACTCCTCCCTTTGTGAACACAGAACTCATATGGGA
ATGAAGAAGTGATCATGAGCTAGAGACTAAAGCATGAGGGGAGTGCTCTTCACTATGCTGGGGTACGAAGGCTGTGAGTT
TTATGAGTCTCCAAGTAAGGCAGCTGAGTAAAAGGTGGTTAAGAGAACTTCTGTGTCTAATAAGAAGAGGGAAAGCAAAC
AGCTAAACCATTAGACCTTGAGCCATACGCCCATCTGGGAATGTTCTGAGTGGCTTCAAATGCAAAGCTGCAGAAAAATA
CTGGCTCCCCCTACCTCCACCCATTCAACCATTACACCTTTTTTTTTTTTTTTAAGAGACAGAGTCTCGTTCTGTTGCCC
AGTCTGGAGTGTACTTGTGCGGTCATAGCTCACTGCAACCTCAAACCTCTGGGCTCAAGTGATCTCCCACTTGATCCACT
CAAGTAGCTAGGACCATGTCTGGCTAAATTTTTTTTTTTTTTTTTTTAATTTTTTGCAGAAACAGGATTGGGGACATGAG
TCTTGCTGTGTTGCCCAGGCTGGTTGCAAACTCATGCCAGTCTCAAACTCCTGGCCTCAAGTGATTCTCCTGCCTTGGCC
TTCCAAAGCACTGGGATTACAGGCATGAGCCTCCTCCGCAGCTGGCCTCATTGTACTTTTTGTCATTAAGAAACTCACCT
GCGTGTTGAAAGTAGAAATCCTTTTCCCTCTCCAAACTGTAAATGGCAAGGACTTTATTTTATTTTGAAGGTTTGGGGCT
TAGGATATTCTGGTTTTTTGTTATGTTTGATTTTTGGTTTAGTTTAGTCATTTTTTTTTTTTTAATCTTAAAACTTCCCA
TATTTTGTCCCTGTAAAATGCTGCCTATAGGAAACACTCCTGCAAAGATTCATGAGCAACTATAAACTGCATTGTGAGTC
ATGAGCTTTCACTACAAGTAGTGAAGCCATAAGTCTGTAGAGGTGCCTTCTTCAGTCCTGTTACCCAGTAGAAGGTATAT
GGCACTCTGCCCTTCCCCAAAGCAGAGTGCCTTGGAAGTGACTCCATTTCTATTGGGTTATTAGTGAAATAGTATCCCAG
TGGTCCTTGTGAATCTCCAGGTCCTGGTCTTGAGTCTTAACCACCGCTTCAGTGGCTTGAGCCAACCACCAGGAACACAG
TCTGGGGATACTTTGCTGCCCAGGAGCTGCTGGCCAGGTCTCCCTCTGCTGATTCCTTGAAAAGCAACAGGAAAGAGCAG
GCTGCTGTGGAGTAGACAGACTTGAGACTCTCTGCACCGTCTTGTTTTGTAAACCCTTTTGCTCCCTTTCCAAGGATTTC
AGTTCAGGAGGAGACCCAGGCGAAGATGACGTCAACAGCCTCTGCATGCAGTCAGTCATAGCTTTGGCTTCTTTCATGGT
CTTGTGCTTTTAACTGGAGCACATTTTCACATTTTTCTTACTGATTAGTAACTAAAGGTGCTTAAAGTAAAGTTTACCAT
TCTGGGATTACCCCTCATATTCTTGTTACCATATAGGGAAGAAGGTCTAAATATGAAGGCCTCATGCTTGTCCTTCTGGT
TCTTAAAAATCATGCAAGTAAAGCAAATCCAAGAGTGCTCTTGAGTACCAGCACCATACGTGCCACCAGGACACAGAACG
CAGGCCAGGTCTGTGAGCTTGGGCTGCATTCAGTCAGGAGAGCCAAGACTAAATACTTAAAATAAGAATATGGAGCTATT
CCAGGCAGTTTGTTAGGCATGAGTTATAGGCTTGTACGGCCAGGAATGAAATTGGTCAGTTCTGCAATTAGAAGGCAATG
CTTGTGATGTTTTATGCTGAGTGGCCTTTAGAGCTTAAAGACTGTCAGCTGTCTTGTCTGCACTGTAACCTCAGTTGCCT
TCTCTGAGCAGGGCACGCTTTCTTTAGGAAATTATGGCACTAACTTGGCAGGTGGTTTCACTGTTCAAGGGCTCCAGCTC
CTGGCACAAGTGATCTCCAGAGTTAAAATTGGAGCAGCTGCTGAGACTTGACTTGCTGCCTGCTTTACCTGTTCCCTCCC
CAAAGAGAGGAAGCACTTTTCATTCATTGCCAGTGTGTATGTGGGAGCTAAACATATATAGCATTTTAGTAAATGCCACT
GCCTACTCTTTTTCTTTTCCTTTTTTAAAAAAGTTACTGAGGCGTGATTGAAATCCAATATACTGCACATTTTAAAAATG
TACAGCTTCATAAATTTTGATGTGTCATTGTTTCCCTTTGAATTCACCCCTCCTTACCCTCCTCTAACAACTACTGATAT
GCTTTTTTGTCAGTGTAGATTTGTTGCATTTTCTAAAGTTTTATATAAATGGAATCATACAGTACGTTCTCTTATGTCTG
CCTTCTTTCACTTGGTATAATTATTTTGAGATTCATCTGTATTGTCCCATGTATCAATTGTTTGTTCCTTTTTGTTGCTA
AATATTTTTCTATATATAGAAACATGTATTTACCAACTTACCCGTTGGTGGATGTTTGGGTTAGTTTATAGTTTTTGACT
ATCGCTAATAAATCTGCTTTGAACATTTGTGTACAAGTTTTTCTGTGGACATAGCCTGTCATTTCTCTTGGATAAATACT
CAAGATCAGAATGGCTGGGTCATATGGGAGGTGTATGTTTAACTTAACTATCAAGCTGTTTTCTGAAGCTTTATGTTATA
TTCCCACTAGCAGTGTATGAGAATACCAGTTCCTTCACATCCTCACTAACACCTGACGTGGTCAGTCTTTTTAGCTTTAC
TCATTCTAATCAGTGGTGGTAGATGCGTTTCCTAGTGGTTTTAATTTGCGTTGTTATAATAACTAGGAATGTTTAGCATC
TTTTCATATGCTTACCTGCCCTCTGTCTTTTTCAATGAAGTATCTGTTCAAATCTTTAGCCCTTTTTTATTGGTTTTCTT
AATTGTTGAATTTTGGTTTGTTATATTCTGGATATAAGTCCTCTATCAGATATGTACTTTGCAAAAGTTTTCTCCCAGTG
TATGGTTTGTCTTTCATTTTCTTAACAGTGCTTTTTAAAGTACTGAATTTATTTTGATGAAGTTCAATTTATTCTTTTAT
AGATAGTGCTTTTTGACATCATACTAAGAAATCTTCACCCAACTCGAGGTCACAAAGATTTCTTTCCTATGTTTTCTTCT
ATAAATTTGATAGGTTTAGTACTTAACATTTAGGTCTAGGATCCATTTTGAGTTAATGCTTGATAATGGTGTGAAGTTTT
TACTGTGTTATGTGTGGATATTTTGTCATTTCAGCCCAATGTAATTTTCATCTCAGACATTGTAGTTTTCATCTCTGAAA
GTTGGAGTCTTATGGTTCTCCTCTACTAATTCTAACATTTGTGTTAGTTCTGGGTTGCTTTCAATTGATTGATAAGTCTC
CTCATTGTGGGTCCTGTTTTCTGCCTCTTTGCATGCCTGGTAATCTTTGGATGCCAGACATTGTGAATTTTGCCTTTTGG
GGTGCTGGATATTTTTATTCCTATAAATTTTCCTGAGTTTTATACTGAGAAGCATTTAAGTTACCCGGAAACAGTTTGAT
GCTTGCGAGTCTTGCTTTTGTGATTTGTTAGGTAGGTCTAGAGCTCAGTTTAGGGCTGATTATTTCCTACTATAGGCAAG
ATCTTCCTGAGTATTCTGCCCAGTGCTTTGTCAATCATGAGCTTCTCCAGTTTGACCGGGGGGTAGTAAGCACTAATCCT
AGCCCTGTGTGAGCACTGGATACTGTTCCTCTAAGCCTTTTGGATAGTTCTTTTCCTGGCCTTGAATAGTTTGCTCAGAT
ACATGCACTGAGAGGGACTCTGCTGAATACTCAAAGAGGACCCTGCAGATCTCTGGGGATCTCTGTATAGCTCTCTCCTG
CTGGTACTGTGTCCTATGGACTCTAGGTGCCTTGAGCTCCACTCCAGGTCCCTCTCCCTGGAAACTCCCAAGGATATAGG
GCTGCCCTTGTTTCCCATGTCTCAGGATTTATTGTTCTTCATTACAGATGTCTGGTGTCCTACAAACCATCGTTGTAGCT
ATTTTGTCTAGGTGGTTTTTAGGTTTTAGTGGACTTTTTGTAGGGAGGAAGGGGTTGGTTGGTTGGTTGTTGGTTGTTTC
ATGAACAAATCTGATCCTTGTCCTCCACCGTGACCAGAAATGGAAGTTCTCACTATCTGTTTTGACATTACAGACTGAAC
AGCATAATTCCTACACATGCACACTCATTCCAGCTTAACAAACACTGCTTCCACCTTCTCCCCCAGGCTGACAACTTAGG
GCCATAGATAAGTGGCCTGTTCCTCCCCACTGGGGAAGCCCTCCTTCTCCTTGTCCTGTAGCTTGTGCCAGTTGTGTGAC
ACCCACTTAATCACATACCACCCCACCCATTTCGGGGGATTATTGTTTAGCTTTCGGACTCGATTATGGGAAATCCTCTC
CTTGGACTCAAGGAACCCCAACATCACTGCCACCACCCAACCCTGCCCTGCGAAGATTTCTCCTTAGAAAGTAGATGAGA
TTGACAGTTGGTGACTGTGGTCTGAAATTCTGGAGCAAGTCTCATGCCCCTTTCCCAGGGACAACAGAGCATCCAAAATA
GCATAGGAAAATTAAGATCCTAGGCAAAGGTCCTGTTTAAAGCTCCTTTACTTAGAAATCCTGCTTCCTGGCTTTTATGG
TTTTAAGATACTAGGGAGAGGTTTGCCCCTCAGTGTCCAAGATAGGCTCAGGAGAGCTGGGGTTAGACAGGCATCCTCAC
ATAGAGCCACTGAAGAACATACACATCTCCATGCTGGCTCAGCAGCAGCAGCAGCAGCAGATTCAGGCTGTGTCCTGCCT
AGTGCTCCTAGCCTGGTACCAGTCAGATAGATAGTTGAAGTATCTCACCTCAGGCAAAGCAACATTGATACATTGATGCA
TGTAGTGTCTGGAGGTTGCTTGGCATTGCATTTGATCAGGAATAAAAAGGAAGTTTAGGGAGTCTGTCTCAGTACCCTGT
GGCTTTCACTGCAATCAAAATACGATCTTGCACAGGTCAGAGCCGTGTTCAAGTTTGGCAAGAAATAAGGCTAATTTTTT
ATAGGTATACCGTACTTTCCAAATTGTGGGTTATGAACCATTAATGCATCATGAAATAAATGTAGTGGGTCACAATCAGC
ATTCTTTTTAAAAATGAGAAGTATATGCCATGTAGTAACTTACATGTAAATTTTGTTTATACACAGACAAAATGTGGGTG
TGTACTGGGTCCTGACATGAGACACTGTTCCCATTGTCGCGGATCAGGGATAGTTCTTTGTGGTTTTAGTTGTTGAGTTC
TGTTTCTTTGTTATTCCTTTCGTGGCAGCACTACATTGTAGCGTGCTCACTAAGTGTCAGAGGTTTACCTCACGCCAGTT
GTGTTCATTTGGCTGCAGGTAACTGAAGACCCAACCTAAGGCAAAGCAGACTTCTTTATTTTTGTAAGACTTCATTAAGA
GCAGTTTCAGATTCTCAGCAAAATTGAGAGGCATGTACAGAGATTTCCCATATATCCCCTGGTCCCACACATGCATAGCC
TCCTGTTATCAACACCCCCCACTAGAATGGTACGTGTGTTGCAATTGACGAACCTGCATTGACACATCATGATCACCCAA
AGTCCATAGTTTACATTAGGGTTCACTCTTGGTGGTGTACATTCTGTGCATTTGGACAAGTGTATAATGGCATGTATCCA
TTATATATAGTATCATACAGAACATTTTCACTGCCCTAAAAATTCTCTGTGCTCCATCTGTTCTTCCCTCCCTCTACCCC
TGACTCCTGGCAATCACTGATCTGTTGACTGTCATCCTAGATTTACCTTCAAAGCACACTTTTAATCACCTCAGAACATG
AGTCTTGAGGGAAGTGGTTTGGGGCTGATTCAGAGCACTGGAATGACCACCTTGTGGTACGCCTGGCCTTCTGATAGTCA
CAGGGTGACTGCCATGCTCCAGACATCTTATCCTCACACAGCATTCAACAGGGAGGGCAGGAACTTTCTTCCCGAGTCTT
TGTTTTTCTTTTTACTAATGAGGTGGGACTTTCCTGGAAGATCCCAGTAGACTTCACAGCAGGTAAAGTAGTGCCCAAAC
TGACCCGTATAGGGGAAGGGCTTGGATTGATTCGAGTTCATCTGCTGGGCCAGGCTGTTGTTGCTGTCGTTGCTCCTGGG
AAGTTGTTGTTTAATTAGGAAGGTGAGGGTGCCACACAGCCTTGCTTCCAGGTGGCCCCTCTGGGCATGTTTTTCTTAAA
ATAACAGACCAGAGAGAAGCTCTTTCTGGTTTTCAGTCTCCTTTGTGGCTCACAGGCCCTGCCACTCCGTGGTTCTGACC
TTGGGTGGGTTACTGAGCCTTGGAGTCGGTTTCCTTATTTCTGTTACAAGCAGTCTCACGAGGGTGGATGGAAAGGCTCC
CTGCCTGGCCAGGGAATGGAGAATCATAGCTGTTCATTGCCTGCTCTCACCCTTACCTCTGAGGTTGGTTGGGTTGGGTT
CCATGTAAGAAGTGCAGCTTGAAGTGGGCTAAAGGCAGTGTGTTTATTGGGTATTGTGGAGCCTGGAGACCTGTTTTTCT
CCCAGGTACTCATTTATAGAGAACTGTTCAAGTCCTGCCATTAGTCATTTCTTTCATCAGGTGGTGACTGCATTCTGGTA
AACGAATGAGCTAAATGCATACCCCAGCTCACCAGTTCTGGGGCACCAGTTCCTTGGAGCAGGTACCGGTCCCCACCCTC
CTGTCTACCTCTTAGTCCTCAGCTCCCAGCTCCAGGCTTCAGGCAGCATTGGTACCCATTCTGCCCCAGGACATCCGTCT
CTACTCCTGCTCTATTAAGATACCACCACCCAACCCCCACCCGTTTCTTACTTTGTTAAAGTCCACATAGTCCAGTAGCT
GTGATAACACTGCCAATTCATCTCTGCCTCCCCATCCTACTTACAAATGTTGACACTGTTTTTTAGGTTGGGATTTTTGT
CAGGATTTTCTTTTTTTCCTAAACTCTTACACAACAGAACTGTAATGTTTTTATGGATCTTCTGAGTAATGAATGCTTAG
AACCATGGTGAGTGCCCACCCTCAGTCTTCCAGTAAAATCAGTTTTGTGTCCATTATATGTTAACCACTGGCTGACCCTC
CAATCTGGGATCCTAATTAGAGAATTCTCAGGAACTCAGTGTCAGCTATCACAATAGGCTGGCAGTGGCTTCCTGAGAAA
GCAATGCCGATGGTGTTTTTGAAAAGGAAGTTGCAGATATCTATTGCAGATGTCTGTTCCTCTTTTCTCATAGCGTCTCT
GGAGTTCCCCTTTTATTGGAAGGCGCCGTCGTGGCTTGTCCAGCTTCTGGGAAACTGGAATAATAGAAAGAGCATGGTAT
TTGGGTTTATAATTTATAACGTAGTTTTACTATTTTACTAAATTATAAATTTACTATTTTTATAATAGTAAATTTTACTA
TTTACTATTTTCACTTCTCCCTGTCTGCCTCAGTTTCTTCATCTGTGAAATGGGGATAGTGCTGTGGAGAAAGAATTGCA
TTCGTTCATGTGTGGAAAGCACCTAGCCCATTTAGAGTAACTCAGAGTGGAACCACTGGCCACAGAGTTGCTAGCAGTTG
GCTGGGTTTACTGAGTTAATTCTTGAAGGGCCACCACTGCAACCTCCTTAGTATTCCTGTTCTCTTCAGTCATCTCTGTT
ACAAAGTATTAGCTGTGCAAAAATGAGCATGGGTTGTTTTGTGGGGCAGCATTGGATAAAATAAGTGGGATGAATGCTGC
ACAAATTCTTTCTTTCATTTCTCTATTTCAGCCTAGGTTGGTTTTTACTTTCCCAGGAAAATTATGACAACTCAGGAACC
AGCCTACAAGGGGCCAGCTTTACGCCCCAGGTTCCCTGTTGGTGTGAGACACTTGGCACTAGAATGAGGGTGAAAGCTTG
CCTTATAGCTTCCTCTTACCACATCCCATAGTGCTGACCCACAGCCTGGAGAGCAGCAATGTGTGTAGGTCACAATTAGT
GAACCACAGAGGAGCCCATGGGGGTGGCAGATGGTGGAGGGGGATTTGCCTGCACTGAACAATGGAGGAGCAATATATAC
ACACATTATATGTGAAAGATGATGGGGGATTTTGGGAAGGAATATTGCTTCTTGCACTGTGTGTGACTTCTAGACATAGT
GTGCACCTCGAGGGACCACAGTTATTTTTAGCTGGGGAGAAAATCCACGGGGTGCTGGGAGAGTCAGGGCAGGAGGAAGT
TTATACTCCCCATCTCCAGAAGAAGGTGGACTGCCGCTCATCTCTGGTACGCGGGGTCCTTTTGTAGTCGAGTTATTGCT
TGGAGTCAGGGAAGAGCATTCACAGGTCTGGAGTAGGACTGTCGCAACTCCTTAGATGTCCAGTGAGGTCACAGGAAACC
CTCCCTAGATACTGCAGTTCCTGCCAGACTCTTCAGCACTGGCATCTCTGATGAGTGCTCTGCTGCTGGTTTCTGACTTG
TCTTGTGTCATTACTCTGCTGCTCATGTTACAGTCGTCTTTTTCACAGGGATGCTTGAAGATGGAAAGAAATTTGATTCC
TCCCGGGACAGAAACAAGCCCTTTAAGTTTATGCTAGGCAAGCAGGAGGTGATCCGAGGCTGGGAAGAAGGGGTTGCCCA
GGTATGCTCTCTCATTTGTTTTGTTTTGCTTTCTAGTATTTACCTTTTATATTTTTTTATAGGTGGCATATTTATACGGT
TCAAAAATAAAAAAAGTGAAAAGTCTCACCCTCATGCCATCCCATCTGACCAATACCCCCACAAGAAGCTCCTGTTGTTA
ATGTTTCTTGTACTGTGGTTTAAGCACATATAAAAACATAACTTTTTTCTTGCTTTCACACACATACTGTTTTGCAGTTT
ACTTTTTCACTTAATGCATTTTTGACACTTGCAATACCACTACATAAAAGAGGAGTAGGCTGGGCGCGGTGGCTCATGCC
TGTAATTCCAGCACTTTGGGAGGCCAAGATGGGTGGATCACCTGAGGTCAGGAGTTCCTGTAATCCCAGCACTTTGGGAG
GCCAAGATGGATGGATCACCTGAGGTCCGGAGTTCGAGACCAGCCTGGCCAACATGGCGAAACCCCATCTCCATTAAAAA
TACAAAAATTAGCCGGGCGTGGTGGCAGGTGCCTGTAATCCCAGCTACTTGGGAGGCCGAGGCAGGAGAATCACTTGAAC
CCAGCAGGCGGAGGTTGTAGTGAGCCAAGATTGTGCCATTGCGCTCCAGCCTGGATGACGAGAGCGAAACTCCATTTCAA
AAAAGAAAGAAAAAATGAGGAGTAAGCTCTGTTACAGCTGCCTAGTATTCGTTTATGTAAGTGTGCTATAATTTACTTGG
CTAGTGCCCTATTAATGAGTATTTGAGTCATTTCCAGTATTTTGCTATTATAAACAATGCTGCAGTAACTCACCTTGTAC
AGACTTCATTTTCCACGTGTGCACATGTTGCCATAGGACTTACTCTCAGAAGTGGGATGAGGGGCTCAAAAGCTGTGTGT
AGTGTTTTTGAGAGGTCTTGTCAAGTTACCATCTCTAGGGGTTGCACTCTGGACTGCCACCACCAGGCTATAAAGGTGCA
ATCTCCTCCCAGCCCCAGCATCACAGTATATTGTTAAATCTTTGGCCTCTGGACAATAAGAGTAAAACATGATATCAGTG
GTTTTAATTTGTATTTATCTATTACCCATATTGTGTGAGACCACTTCTGAGACGTCATACTTATGGAGAAAGTCATTTCG
TTTGTCTTGAGTGTGTTTCCTAATCTCTTTCCTCCCCATTTGTGGAAACAGCTTTTGTTCTGCCAACACTACAAAATTCC
CAGGAGACAATAGGGACCCAGGGTTGCCAAATTTTAGTTGGATTCTGTCTTTCCATCAAACCTAGGAATTTTTTCTTGGC
TCTAACCAGGTAAAGGGATGTTTTTCAGTGACCTGAGACCCAAGGAACTTTATAATTAGGCTCTGCATGATGGGTAATTA
GTCTGCTTCCCTCTCACCCAGGAGAATTAGAAATTTAACCAAGATGAAAAGACAGATTTCTGTCTCTCTCTTTTCCAGAA
TACACATTGCTCTACTTCCTCTATAAAATATCACTGATTTATCTCCAAATAAACTGCTCAACTTTCAGGAACTTGAAGCC
ATCCCACTCCCAGGTGTCTGGGTTTCTGTTCCTGCAGGGCAGAGGGTTGGCAGTGTGAGGAAGAGGCTTTGTAGTTTACT
TCCCTTGGGAAACCTTGCCAACCATAGCTTTTTGCCTCTGTCTCCCTAGTCTGTCTGGCTCTTGGATCTGTAGCCCATCC
CCCATCTTTCATGCCAGCCATTGTTCATACCACAACCCATCTTCTGTGACTGCTCCAGCATTGGAACAATCACTGCGTTG
TATGTACTGAGTGCTGTATCTGCCATCGAGATAGTGTTATCGGCCTACTTCACTTCCCAGGCTTGGAGAGGCATGGTCGA
GTATTGGACAGATGCCTGACTCCCCCTTTAACTGGTATTTTGGGGTCAGTCACAGCCCTGTCATTTGTGAGAAGTCTGGG
TAGTTTGAGATCTACATAAAATATCTTTTAAATTCTTCATAGCATATTTTTTCACCAAGTGAGTTAAAAACACAGGAAGA
AGGGGAGATTGACTTGTGACCCTTTTCCTTTCCTTTTGATATTGTTTTGGTTTTACATGTTTGCAGGCGTGGAGTCCTGC
CTGCCACAAGGACCATTTTGGCAGCTTTCTTTCATCCATCTTGGACATCTTTTCATGTTAATACATTTAAAGCCACCACT
ATATGATTTCTCATGACTAATCCCTGGTGTGGATATGCCTATGAAACCACTCCTTCTGTGATGGACTTTTGAGTTGTTAG
CAGAATATTCTGGAAATAGAATTGCTGAGTCAAGGAATATGATTGTTTTGAATTGTACAAGGTAAAGCCATACCTCACTA
TCCTTACCACCTTGGTCCAACATGTCCCAGCTTCTGAGGGGAGCAAGGACTAGACGCTTCACAGCCTGGAGCTTCCTCTT
TATTCATCCTCTGTCTGGTGGAGTTGGAAAGTCGGGAACATACACATGGAGACCAAAAGCAGAGATAAGTCAAAGGATGG
AAATACTGCAGAGAACCTGCTCACTGTTCAGAAAGTAGATATTTTATACTTATTTGTGTATTTAATTTGAAACTGAAAAT
ATACACAAATATATTTTTTAAAGTAGAAATCTCTCCTTACTGGTCACTCACTATCCATACTGTTCTCCTCACAGCAAATG
TCTGGTATGTCCTTCCAAAGATGTTTTCTGTTGTAGGCATATCAATATTTTCACAAATGGTATTCAGTAAATGCTATTTT
GTAGCCCAGAAAATCATATTGTCTTTTTTGAAGTTTTCCTATATGGGTAAAAGAGTATAAATAGAAAAAATACAGAAAAA
ATAGACTACCCTCAAGTATTACTTCCTGTGTATATATTTTTTTAAAGCAAAGTTGAGTATTCCTTTTTCAAGAAGAGCAT
AGATGGCACTTAACATGTCCTTTAAGTGACAGATCACTGAAGGGGACTAGGTGGTGAGACATCTGGAATGTTACCTGCCT
AGCATTAGTCATTAAGACTTGCGTAGAAAGGTTGAGGGCCTGACCGTTCTGAGAGTCAGGAGGGGTTTTGAACTGCCATT
GGGCTTCTTGGAGTGAGATGCAGGGGTGATGGAATATGACTGCCAACCTCCAAGTCCTGCACAAGGAGGTGGTGATGCCT
GGGCAGCTGCAAAGTCACTGGAAAGTCAATACCATCCTGGCCAAGGAACACCTAGGTAAACAGCTCTTTTTCTTACAGAG
ACAGTTGGGGCATGTGTCCAGCTGAGTCTGTCTTCCTTGTTCTTTTCACAGATGAGTGTGGGTCAGAGAGCCAAACTGAC
TATATCTCCAGATTATGCCTATGGTGCCACTGGGCACCCAGGCATCATCCCACCACATGCCACTCTCGTCTTCGATGTGG
AGCTTCTAAAACTGGAATGACAGGAATGGCCTCCTCCCTTAGCTCCCTGTTCTTGGGTAAGGAAATGGAATACTGAAGGG
CCCTTCACTGCCTTTGCTCCTCCCATGTTATGCCCAGCGTTTGATGGGTAGCAGAGAGAACAAAAAACACCACAAGGCTA
TTTTTCCCCCTGCATTCTTTCTGTATTGAGTATCCTTTCAGTGTTATTAGTGTATGCTTTGAATGTAAAAATTGGTCACC
CTAAGGAAAGGAATTGGCATGTGTATGTTCCCAGTTCAACTCATGGAGATGGCAGCTGTTTAAATGTTTTTCTATGTAGT
TTATAAATTAAAACTGAATTGAGGACTATGGAAATGTAGGCCAAATTTGTAGTGCCAACATTTTAGTTCTTTGGAAATAA
GACTCTTAATGAATGACTTTGTTCTACCCTGTGTTTCTAGAAGCTAGAGGGGGAAAAAAAAAGCCCTTTGGATATGAATA
TCATGTCCTAGCTTCTGCGGCTCTCTCTTCACTGTGGTTTGTGGTTACTGCCTATTAGATGGTATGAGGGAGGCATTCCT
GCATCGGTCCACCTGCTCAGGGTCCACACCCAGGACACTTGAGGCCCCCAGGCCAGCTTATCAGTGAGTGAAGTGGAAAA
ATGAAGCCAGAGGATGCTTGTGAAGTTGAAAGGATGCTCTTAGATCAGACAGTTCTAGGAAGGGATCTTAGGGGCCTCTG
CATCAGCTTTATTGTGCAACAGTAAGGAAACAGGGCCAGAGAGAAAGGCCTTACTCAAGGTCACATCCAGGCAGTGGCAA
AGTAGGACCAGAGCCCCTGTTTGTTGATTTTCCCCTCTTCCACCCTCATTTCTTAGGAACTAAACTCAGTATCCTAGTAG
CACGTAACTTTTCATGTAAGTGTTAGAATCATTAAGTACATGAATGCTACTGGCTTCCTTCCAACTGGCCCCAGACCTTT
TTATTTGCTCCCCTCCTGCCATAGGAACCAGAGGGTCACAGCCAAGGCCTGGGTGAGGACACTTTTGTTTGAAAGCCACA
ACAAATGGCTGCCATCCTATTTGTGATGGCAGTCAGAGCTACTTGTAACCTGGTCCTGTTGTGCACATCTGTAAGTGGAG
GGGCTTTTTAAACTCTCTGTTTGAACCACACACACCTTGGTAATACAGGCCTGGTTAAGTTTGATAACTGGTTTCTTCAC
CTGTCATTGCTACTGGGAGGGAATCCCTGGCACTTTACAGGGCCTTTGTCTGCCCAGAGGTCTGCACCTAGGCCAAAATC
CCTTTCCTGTTCTTTGAGAGCTGAGTCATTTTTTGAACATAACTGTACTCGAGGGAGCCTTGGAATTATTTTCCTGGTTG
GGAACAGGCTTTCTGTAAACTTGATGAGGTAGAGGGAGGGGAGAGAGGGATAAAGGCTACAAGTCACCCCGAGTAACCCT
CCCAACCCACTGCCAAAGAATGTCTCAGCTTCTTGCAAGAGTCTGGAAGGAAAATCCAAGGGCAAACCCAGAAAGTTTTA
AGTTGAGTGAATGAATGAATACTGGAGATATTTTCCCAGTATACTCAACATTATGAATGACCAGTTTATTCTCAGTCTGG
ACTGCACATGAGAGTCACCTGGGAAATTTTTAAGACTTTCCTGATGCCCAGGTCAAACCCTAAACCAGTTAATCATAATC
ATGGGAGTGGAACCCAGGCATTAAGAGTTTTTTAAAGCCCCCAGGTGATGCCTATATGTAGCACAGTTTGAGACCCAATG
ATAGTGGGGAACTGTATTGTCAGCAGCATGGGTGGCTAGCCCTCCTGCTGTCCTCAGCAAGGCAAACTTAACCTTAGATT
AAACAAAACACACAGATCAATTTAAGGAGAAAGTTTGTTTCACCTGGGACCCAGCCCAAGTCTTTCTGGCTGTCTCCAGC
TGGAACAGAAGTGGCTTGGTCTCAGACTGCTCAGCTGTTGGGGAAGGGATTTGGCGTGGCAGATGGCATCGTGGCTGTCG
CCACTGCACACAAAGAACACTGAGTTGCTGGAAACTCACAGATTTTCTGTCCCCAACAGATCTGCCATGGAGGGATCTGG
TGCCTCCAGACATGTGCACATGAATCCATATGGAGCTTTTCCTGATGTTCCACTCCACTTTGTATAGACATCTGCCCTGA
CTGAATGTGTTCTGTCACTCAGCTTTGCTTCCGACACCTCTGTTTCCTCTTCCCCTTTCTCCTCGTATGTGTGTTTACCT
AAACTATATGCCATAAACCTCAAGTTATTCATTTTATTTTGTTTTCATTTTGGGGTGAAGATTCAGTTTCAGTCTTTTGG
ATATAGGTTTCCAATTAAGTACATGGTCAAGTATTAACAGCACAAGTGGTAGGTTAACATTAGAATAGGAATTGGTGTTG
GGGGGGGGGTTTGCAAGAATATTTTATTTTAATTTTTTGGATGAAATTTTTATCTATTATATATTAAACATTCTTGCTGC
TGCGCTGCAAAGCCATAGCAGATTTGAGGCGCTGTTGAGGACTGAATTACTCTCCAAGTTGAGAGATGTCTTTGGGTTAA
ATTAAAAGCCCTACCTAAAACTGAGGTGGGGATGGGGAGAGCCTTTGCCTCCACCATTCCCACCCACCCTCCCCTTAAAC
CCTCTGCCTTTGAAAGTAGATCATGTTCACTGCAATGCTGGACACTACAGGTATCTGTCCCTGGGCCAGCAGGGACCTCT
GAAGCCTTCTTTGTGGCCTTTTTTTTTTTTCATCCTGTGGTTTTTCTAATGGACTTTCAGGAATTTTGTAATCTCATAAC
TTTCCAAGCTCCACCACTTCCTAAATCTTAAGAACTTTAATTGACAGTTTCAATTGAAGGTGCTGTTTGTAGACTTAACA
CCCAGTGAAAGCCCAGCCATCATGACAAATCCTTGAATGTTCTCTTAAGAAAATGATGCTGGTCATCGCAGCTTCAGCAT
CTCCTGTTTTTTGATGCTTGGCTCCCTCTGCTGATCTCAGTTTCCTGGCTTTTCCTCCCTCAGCCCCTTCTCACCCCTTT
GCTGTCCTGTGTAGTGATTTGGTGAGAAATCGTTGCTGCACCCTTCCCCCAGCACCATTTATGAGTCTCAAGTTTTATTA
TTGCAATAAAAGTGCTTTATGCCGGCTTTTCTCAG
|
|
|
| |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Primary source |
RefSeq : NM_054014.2 (GI:206725517)
|
Name |
FK506 binding protein 1A, 12kDa (FKBP1A), transcript variant 12A
|
Type of transcript |
mRNA
|
Organism |
Homo sapiens
|
Length |
906 nt
|
Map |
20p13
|
Location |
Chromosome 20 (NC_000020.10) strand : -
1352359...1352883 | 1356134...1356246 | 1373477...1373524 | 1373605...1373815 |
|
|
|
|
|
|
|
|
|
|
|
|
|
Exon(s) |
Start |
End |
Length |
is coding |
Exon 1
|
1
|
211
|
211
|
1
|
Exon 2
|
212
|
259
|
48
|
1
|
Exon 3
|
260
|
372
|
113
|
1
|
Exon 4b
|
373
|
897
|
525
|
1
|
|
|
|
|
|
|
|
|
|
|
|
|
ID |
Class |
Location |
Mutation |
Length |
is synonymous |
Source |
rs2296039
|
SNP
|
798
|
c/t
|
1
|
?
|
dbSNP
|
rs6105016
|
SNP
|
840
|
a/g
|
1
|
?
|
dbSNP
|
rs36059165
|
insertion
|
753
|
-/c
|
1
|
?
|
dbSNP
|
|
|
|
|
|
|
|
|
|
|
|
|
Primary source |
NCBI : CCDS13014
|
Nucleotide |
FKBP1A, mRNA isoform 12A[NM_054014.2] : 175...501
|
Length |
327
|
Location |
Chromosome 20 (NC_000020.10) strand : -
1352755...1352883 | 1356134...1356246 | 1373477...1373524 | 1373605...1373641 |
|
Start codon |
1
|
Translation |
NP_463460.1 |
|
|
|
|
|
|
|
|
|
|
|
|
1 |
TTTCCGGGAC |
GTCGCGCGCC |
GTGTGGGGCG |
CGCACGCAGG |
GCTGGGCGTG |
AGGGGGCGTG |
CGCGTGCGCA |
GGCGACGCGC |
|
81 |
CGAGGTACTA |
GGCAGAGCCG |
TGGAACCGCC |
GCCAGGTCGC |
TGTTGGTCCA |
CGCCGCCCGT |
CGCGCCGCCC |
GCCCGCTCAG |
|
161 |
CGTCCGCCGC |
CGCCATGGGA |
GTGCAGGTGG |
AAACCATCTC |
CCCAGGAGAC |
GGGCGCACCT |
TCCCCAAGCG |
CGGCCAGACC |
|
241 |
TGCGTGGTGC |
ACTACACCGG |
GATGCTTGAA |
GATGGAAAGA |
AATTTGATTC |
CTCCCGGGAC |
AGAAACAAGC |
CCTTTAAGTT |
|
321 |
TATGCTAGGC |
AAGCAGGAGG |
TGATCCGAGG |
CTGGGAAGAA |
GGGGTTGCCC |
AGATGAGTGT |
GGGTCAGAGA |
GCCAAACTGA |
|
401 |
CTATATCTCC |
AGATTATGCC |
TATGGTGCCA |
CTGGGCACCC |
AGGCATCATC |
CCACCACATG |
CCACTCTCGT |
CTTCGATGTG |
|
481 |
GAGCTTCTAA |
AACTGGAATG |
ACAGGAATGG |
CCTCCTCCCT |
TAGCTCCCTG |
TTCTTGGGTA |
AGGAAATGGA |
ATACTGAAGG |
|
561 |
GCCCTTCACT |
GCCTTTGCTC |
CTCCCATGTT |
ATGCCCAGCG |
TTTGATGGGT |
AGCAGAGAGA |
ACAAAAAACA |
CCACAAGGCT |
|
641 |
ATTTTTCCCC |
CTGCATTCTT |
TCTGTATTGA |
GTATCCTTTC |
AGTGTTATTA |
GTGTATGCTT |
TGAATGTAAA |
AATTGGTCAC |
|
721 |
CCTAAGGAAA |
GGAATTGGCA |
TGTGTATGTT |
CCCAGTTCAA |
CTCATGGAGA |
TGGCAGCTGT |
TTAAATGTTT |
TTCTATGTAG |
|
801 |
TTTATAAATT |
AAAACTGAAT |
TGAGGACTAT |
GGAAATGTAG |
GCCAAATTTG |
TAGTGCCAAC |
ATTTTAGTTC |
TTTGGAAATA |
|
881 |
AGACTCTTAA |
TGAATGAAAA |
AAAAAA |
|
|
|
|
|
|
|
|
|
|
|
|
>gi|206725517|ref|NM_054014.2|FK506 binding protein 1A, 12kDa (FKBP1A), transcript variant 12A
TTTCCGGGACGTCGCGCGCCGTGTGGGGCGCGCACGCAGGGCTGGGCGTGAGGGGGCGTGCGCGTGCGCAGGCGACGCGC
CGAGGTACTAGGCAGAGCCGTGGAACCGCCGCCAGGTCGCTGTTGGTCCACGCCGCCCGTCGCGCCGCCCGCCCGCTCAG
CGTCCGCCGCCGCCATGGGAGTGCAGGTGGAAACCATCTCCCCAGGAGACGGGCGCACCTTCCCCAAGCGCGGCCAGACC
TGCGTGGTGCACTACACCGGGATGCTTGAAGATGGAAAGAAATTTGATTCCTCCCGGGACAGAAACAAGCCCTTTAAGTT
TATGCTAGGCAAGCAGGAGGTGATCCGAGGCTGGGAAGAAGGGGTTGCCCAGATGAGTGTGGGTCAGAGAGCCAAACTGA
CTATATCTCCAGATTATGCCTATGGTGCCACTGGGCACCCAGGCATCATCCCACCACATGCCACTCTCGTCTTCGATGTG
GAGCTTCTAAAACTGGAATGACAGGAATGGCCTCCTCCCTTAGCTCCCTGTTCTTGGGTAAGGAAATGGAATACTGAAGG
GCCCTTCACTGCCTTTGCTCCTCCCATGTTATGCCCAGCGTTTGATGGGTAGCAGAGAGAACAAAAAACACCACAAGGCT
ATTTTTCCCCCTGCATTCTTTCTGTATTGAGTATCCTTTCAGTGTTATTAGTGTATGCTTTGAATGTAAAAATTGGTCAC
CCTAAGGAAAGGAATTGGCATGTGTATGTTCCCAGTTCAACTCATGGAGATGGCAGCTGTTTAAATGTTTTTCTATGTAG
TTTATAAATTAAAACTGAATTGAGGACTATGGAAATGTAGGCCAAATTTGTAGTGCCAACATTTTAGTTCTTTGGAAATA
AGACTCTTAATGAATGAAAAAAAAAA
|
|
|
| |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Primary source |
RefSeq : NM_000801.3 (GI:206725516)
|
Name |
FK506 binding protein 1A, 12kDa (FKBP1A), transcript variant 12B
|
Type of transcript |
mRNA
|
Organism |
Homo sapiens
|
Length |
1655 nt
|
Map |
20p13
|
Location |
Chromosome 20 (NC_000020.10) strand : -
1349621...1350715 | 1352719...1352883 | 1356134...1356246 | 1373477...1373524 |
1373605...1373815 |
|
|
|
|
|
|
|
|
|
|
|
|
|
Exon(s) |
Start |
End |
Length |
is coding |
Exon 1
|
1
|
211
|
211
|
1
|
Exon 2
|
212
|
259
|
48
|
1
|
Exon 3
|
260
|
372
|
113
|
1
|
Exon 4a
|
373
|
537
|
165
|
1
|
Exon 5
|
538
|
1632
|
1095
|
1
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Primary source |
NCBI : CCDS13014
|
Nucleotide |
FKBP1A, mRNA isoform 12B[NM_000801.3] : 175...501
|
Length |
327
|
Location |
Chromosome 20 (NC_000020.10) strand : -
1352755...1352883 | 1356134...1356246 | 1373477...1373524 | 1373605...1373641 |
|
Start codon |
1
|
Translation |
NP_000792.1 |
|
|
|
|
|
|
|
|
|
|
|
|
1 |
TTTCCGGGAC |
GTCGCGCGCC |
GTGTGGGGCG |
CGCACGCAGG |
GCTGGGCGTG |
AGGGGGCGTG |
CGCGTGCGCA |
GGCGACGCGC |
|
81 |
CGAGGTACTA |
GGCAGAGCCG |
TGGAACCGCC |
GCCAGGTCGC |
TGTTGGTCCA |
CGCCGCCCGT |
CGCGCCGCCC |
GCCCGCTCAG |
|
161 |
CGTCCGCCGC |
CGCCATGGGA |
GTGCAGGTGG |
AAACCATCTC |
CCCAGGAGAC |
GGGCGCACCT |
TCCCCAAGCG |
CGGCCAGACC |
|
241 |
TGCGTGGTGC |
ACTACACCGG |
GATGCTTGAA |
GATGGAAAGA |
AATTTGATTC |
CTCCCGGGAC |
AGAAACAAGC |
CCTTTAAGTT |
|
321 |
TATGCTAGGC |
AAGCAGGAGG |
TGATCCGAGG |
CTGGGAAGAA |
GGGGTTGCCC |
AGATGAGTGT |
GGGTCAGAGA |
GCCAAACTGA |
|
401 |
CTATATCTCC |
AGATTATGCC |
TATGGTGCCA |
CTGGGCACCC |
AGGCATCATC |
CCACCACATG |
CCACTCTCGT |
CTTCGATGTG |
|
481 |
GAGCTTCTAA |
AACTGGAATG |
ACAGGAATGG |
CCTCCTCCCT |
TAGCTCCCTG |
TTCTTGGATC |
TGCCATGGAG |
GGATCTGGTG |
|
561 |
CCTCCAGACA |
TGTGCACATG |
AATCCATATG |
GAGCTTTTCC |
TGATGTTCCA |
CTCCACTTTG |
TATAGACATC |
TGCCCTGACT |
|
641 |
GAATGTGTTC |
TGTCACTCAG |
CTTTGCTTCC |
GACACCTCTG |
TTTCCTCTTC |
CCCTTTCTCC |
TCGTATGTGT |
GTTTACCTAA |
|
721 |
ACTATATGCC |
ATAAACCTCA |
AGTTATTCAT |
TTTATTTTGT |
TTTCATTTTG |
GGGTGAAGAT |
TCAGTTTCAG |
TCTTTTGGAT |
|
801 |
ATAGGTTTCC |
AATTAAGTAC |
ATGGTCAAGT |
ATTAACAGCA |
CAAGTGGTAG |
GTTAACATTA |
GAATAGGAAT |
TGGTGTTGGG |
|
881 |
GGGGGGGTTT |
GCAAGAATAT |
TTTATTTTAA |
TTTTTTGGAT |
GAAATTTTTA |
TCTATTATAT |
ATTAAACATT |
CTTGCTGCTG |
|
961 |
CGCTGCAAAG |
CCATAGCAGA |
TTTGAGGCGC |
TGTTGAGGAC |
TGAATTACTC |
TCCAAGTTGA |
GAGATGTCTT |
TGGGTTAAAT |
|
1041 |
TAAAAGCCCT |
ACCTAAAACT |
GAGGTGGGGA |
TGGGGAGAGC |
CTTTGCCTCC |
ACCATTCCCA |
CCCACCCTCC |
CCTTAAACCC |
|
1121 |
TCTGCCTTTG |
AAAGTAGATC |
ATGTTCACTG |
CAATGCTGGA |
CACTACAGGT |
ATCTGTCCCT |
GGGCCAGCAG |
GGACCTCTGA |
|
1201 |
AGCCTTCTTT |
GTGGCCTTTT |
TTTTTTTTCA |
TCCTGTGGTT |
TTTCTAATGG |
ACTTTCAGGA |
ATTTTGTAAT |
CTCATAACTT |
|
1281 |
TCCAAGCTCC |
ACCACTTCCT |
AAATCTTAAG |
AACTTTAATT |
GACAGTTTCA |
ATTGAAGGTG |
CTGTTTGTAG |
ACTTAACACC |
|
1361 |
CAGTGAAAGC |
CCAGCCATCA |
TGACAAATCC |
TTGAATGTTC |
TCTTAAGAAA |
ATGATGCTGG |
TCATCGCAGC |
TTCAGCATCT |
|
1441 |
CCTGTTTTTT |
GATGCTTGGC |
TCCCTCTGCT |
GATCTCAGTT |
TCCTGGCTTT |
TCCTCCCTCA |
GCCCCTTCTC |
ACCCCTTTGC |
|
1521 |
TGTCCTGTGT |
AGTGATTTGG |
TGAGAAATCG |
TTGCTGCACC |
CTTCCCCCAG |
CACCATTTAT |
GAGTCTCAAG |
TTTTATTATT |
|
1601 |
GCAATAAAAG |
TGCTTTATGC |
CGGCTTTTCT |
CAAAAAAAAA |
AAAAAAAAAA |
AAAAA |
|
|
|
|
|
|
|
|
|
|
|
|
>gi|206725516|ref|NM_000801.3|FK506 binding protein 1A, 12kDa (FKBP1A), transcript variant 12B
TTTCCGGGACGTCGCGCGCCGTGTGGGGCGCGCACGCAGGGCTGGGCGTGAGGGGGCGTGCGCGTGCGCAGGCGACGCGC
CGAGGTACTAGGCAGAGCCGTGGAACCGCCGCCAGGTCGCTGTTGGTCCACGCCGCCCGTCGCGCCGCCCGCCCGCTCAG
CGTCCGCCGCCGCCATGGGAGTGCAGGTGGAAACCATCTCCCCAGGAGACGGGCGCACCTTCCCCAAGCGCGGCCAGACC
TGCGTGGTGCACTACACCGGGATGCTTGAAGATGGAAAGAAATTTGATTCCTCCCGGGACAGAAACAAGCCCTTTAAGTT
TATGCTAGGCAAGCAGGAGGTGATCCGAGGCTGGGAAGAAGGGGTTGCCCAGATGAGTGTGGGTCAGAGAGCCAAACTGA
CTATATCTCCAGATTATGCCTATGGTGCCACTGGGCACCCAGGCATCATCCCACCACATGCCACTCTCGTCTTCGATGTG
GAGCTTCTAAAACTGGAATGACAGGAATGGCCTCCTCCCTTAGCTCCCTGTTCTTGGATCTGCCATGGAGGGATCTGGTG
CCTCCAGACATGTGCACATGAATCCATATGGAGCTTTTCCTGATGTTCCACTCCACTTTGTATAGACATCTGCCCTGACT
GAATGTGTTCTGTCACTCAGCTTTGCTTCCGACACCTCTGTTTCCTCTTCCCCTTTCTCCTCGTATGTGTGTTTACCTAA
ACTATATGCCATAAACCTCAAGTTATTCATTTTATTTTGTTTTCATTTTGGGGTGAAGATTCAGTTTCAGTCTTTTGGAT
ATAGGTTTCCAATTAAGTACATGGTCAAGTATTAACAGCACAAGTGGTAGGTTAACATTAGAATAGGAATTGGTGTTGGG
GGGGGGGTTTGCAAGAATATTTTATTTTAATTTTTTGGATGAAATTTTTATCTATTATATATTAAACATTCTTGCTGCTG
CGCTGCAAAGCCATAGCAGATTTGAGGCGCTGTTGAGGACTGAATTACTCTCCAAGTTGAGAGATGTCTTTGGGTTAAAT
TAAAAGCCCTACCTAAAACTGAGGTGGGGATGGGGAGAGCCTTTGCCTCCACCATTCCCACCCACCCTCCCCTTAAACCC
TCTGCCTTTGAAAGTAGATCATGTTCACTGCAATGCTGGACACTACAGGTATCTGTCCCTGGGCCAGCAGGGACCTCTGA
AGCCTTCTTTGTGGCCTTTTTTTTTTTTCATCCTGTGGTTTTTCTAATGGACTTTCAGGAATTTTGTAATCTCATAACTT
TCCAAGCTCCACCACTTCCTAAATCTTAAGAACTTTAATTGACAGTTTCAATTGAAGGTGCTGTTTGTAGACTTAACACC
CAGTGAAAGCCCAGCCATCATGACAAATCCTTGAATGTTCTCTTAAGAAAATGATGCTGGTCATCGCAGCTTCAGCATCT
CCTGTTTTTTGATGCTTGGCTCCCTCTGCTGATCTCAGTTTCCTGGCTTTTCCTCCCTCAGCCCCTTCTCACCCCTTTGC
TGTCCTGTGTAGTGATTTGGTGAGAAATCGTTGCTGCACCCTTCCCCCAGCACCATTTATGAGTCTCAAGTTTTATTATT
GCAATAAAAGTGCTTTATGCCGGCTTTTCTCAAAAAAAAAAAAAAAAAAAAAAAA
|
|
|
| |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Exon number |
4a
|
Length |
165 nt
|
Location |
Chromosome 20 (NC_000020.10) : 1352719...1352883 (-)
|
Is part of |
FKBP1A, mRNA isoform 12B
(NM_000801.3)
|
Sequence |
Show
|
|
ATGAGTGTGGGTCAGAGAGCCAAACTGACTATATCTCCAGATTATGCCTATGGTGCCACTGGGCACCCAGGCATCATCCC
ACCACATGCCACTCTCGTCTTCGATGTGGAGCTTCTAAAACTGGAATGACAGGAATGGCCTCCTCCCTTAGCTCCCTGTT
CTTGG
|
|
|
|
|
|
|
|
|
|
|
|
|
Exon number |
4b
|
Length |
525 nt
|
Location |
Chromosome 20 (NC_000020.10) : 1352359...1352883 (-)
|
Is part of |
FKBP1A, mRNA isoform 12A
(NM_054014.2)
|
Sequence |
Show
|
|
ATGAGTGTGGGTCAGAGAGCCAAACTGACTATATCTCCAGATTATGCCTATGGTGCCACTGGGCACCCAGGCATCATCCC
ACCACATGCCACTCTCGTCTTCGATGTGGAGCTTCTAAAACTGGAATGACAGGAATGGCCTCCTCCCTTAGCTCCCTGTT
CTTGGGTAAGGAAATGGAATACTGAAGGGCCCTTCACTGCCTTTGCTCCTCCCATGTTATGCCCAGCGTTTGATGGGTAG
CAGAGAGAACAAAAAACACCACAAGGCTATTTTTCCCCCTGCATTCTTTCTGTATTGAGTATCCTTTCAGTGTTATTAGT
GTATGCTTTGAATGTAAAAATTGGTCACCCTAAGGAAAGGAATTGGCATGTGTATGTTCCCAGTTCAACTCATGGAGATG
GCAGCTGTTTAAATGTTTTTCTATGTAGTTTATAAATTAAAACTGAATTGAGGACTATGGAAATGTAGGCCAAATTTGTA
GTGCCAACATTTTAGTTCTTTGGAAATAAGACTCTTAATGAATGA
|
|
|
|
|
|
|
|
|
|
|
|
|
Exon number |
5
|
Length |
1095 nt
|
Location |
Chromosome 20 (NC_000020.10) : 1349621...1350715 (-)
|
Is part of |
FKBP1A, mRNA isoform 12B
(NM_000801.3)
|
Sequence |
Show
|
|
ATCTGCCATGGAGGGATCTGGTGCCTCCAGACATGTGCACATGAATCCATATGGAGCTTTTCCTGATGTTCCACTCCACT
TTGTATAGACATCTGCCCTGACTGAATGTGTTCTGTCACTCAGCTTTGCTTCCGACACCTCTGTTTCCTCTTCCCCTTTC
TCCTCGTATGTGTGTTTACCTAAACTATATGCCATAAACCTCAAGTTATTCATTTTATTTTGTTTTCATTTTGGGGTGAA
GATTCAGTTTCAGTCTTTTGGATATAGGTTTCCAATTAAGTACATGGTCAAGTATTAACAGCACAAGTGGTAGGTTAACA
TTAGAATAGGAATTGGTGTTGGGGGGGGGGTTTGCAAGAATATTTTATTTTAATTTTTTGGATGAAATTTTTATCTATTA
TATATTAAACATTCTTGCTGCTGCGCTGCAAAGCCATAGCAGATTTGAGGCGCTGTTGAGGACTGAATTACTCTCCAAGT
TGAGAGATGTCTTTGGGTTAAATTAAAAGCCCTACCTAAAACTGAGGTGGGGATGGGGAGAGCCTTTGCCTCCACCATTC
CCACCCACCCTCCCCTTAAACCCTCTGCCTTTGAAAGTAGATCATGTTCACTGCAATGCTGGACACTACAGGTATCTGTC
CCTGGGCCAGCAGGGACCTCTGAAGCCTTCTTTGTGGCCTTTTTTTTTTTTCATCCTGTGGTTTTTCTAATGGACTTTCA
GGAATTTTGTAATCTCATAACTTTCCAAGCTCCACCACTTCCTAAATCTTAAGAACTTTAATTGACAGTTTCAATTGAAG
GTGCTGTTTGTAGACTTAACACCCAGTGAAAGCCCAGCCATCATGACAAATCCTTGAATGTTCTCTTAAGAAAATGATGC
TGGTCATCGCAGCTTCAGCATCTCCTGTTTTTTGATGCTTGGCTCCCTCTGCTGATCTCAGTTTCCTGGCTTTTCCTCCC
TCAGCCCCTTCTCACCCCTTTGCTGTCCTGTGTAGTGATTTGGTGAGAAATCGTTGCTGCACCCTTCCCCCAGCACCATT
TATGAGTCTCAAGTTTTATTATTGCAATAAAAGTGCTTTATGCCGGCTTTTCTCA
|
|
|
|
|
|
|
|
|
|
|
|
|
Primary source |
Uniprot : P62942
|
Name |
Peptidyl-prolyl cis-trans isomerase FKBP1A
|
Alternative name(s) |
12 kDa FK506-binding protein FK506-binding protein 1A Immunophilin FKBP12 Rotamase
|
Synonym(s) |
12 kDa FKBP FKBP-12 FKBP-1A PPIase FKBP1A
|
Organism |
Homo sapiens
|
Length |
108 aa
|
Protein existence |
---
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
General annotation (Comments)
|
top
|
|
|
|
|
|
|
Catalytic activity
|
Peptidylproline (omega=180) = peptidylproline (omega=0).
|
Enzyme regulation
|
Inhibited by both FK506 and rapamycin.
|
Function
|
May play a role in modulation of ryanodine receptor isoform-1 (RYR-1), a component of the calcium release channel of skeletal muscle sarcoplasmic reticulum. There are four molecules of FKBP12 per skeletal muscle RYR. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
|
Similarity
|
Belongs to the FKBP-type PPIase family. FKBP1 subfamily.
Contains 1 PPIase FKBP-type domain.
|
Subcellular location
|
Cytoplasm.
|
|
|
|
|
|
|
|
|
|
|
|
|
Biological process
|
'de novo' protein folding [GO:0006458]
SMAD protein complex assembly [GO:0007183]
protein maturation by protein folding [GO:0022417]
positive regulation of protein ubiquitination [GO:0031398]
positive regulation of protein binding [GO:0032092]
negative regulation of protein phosphatase type 2B activity [GO:0032513]
regulation of activin receptor signaling pathway [GO:0032925]
beta-amyloid formation [GO:0034205]
protein refolding [GO:0042026]
T cell activation [GO:0042110]
positive regulation of I-kappaB kinase/NF-kappaB cascade [GO:0043123]
fibril organization [GO:0043206]
regulation of immune response [GO:0050776]
ventricular cardiac muscle tissue morphogenesis [GO:0055010]
regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]
heart trabecula formation [GO:0060347]
|
Cellular component
|
cytosol [GO:0005829]
terminal cisterna [GO:0014802]
|
Molecular function
|
peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
signal transducer activity [GO:0004871]
FK506 binding [GO:0005528]
type I transforming growth factor beta receptor binding [GO:0034713]
SMAD binding [GO:0046332]
activin binding [GO:0048185]
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Alternative product(s)
|
top
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Feature key |
Position
|
Length
|
Description
|
Feature identifier
|
Molecule processing |
|
|
|
|
Initiator methionine
|
1 - 1
|
1
|
Removed
|
P62942-INIT_MET-1
|
Region |
|
|
|
|
Domain
|
20 - 108
|
89
|
PPIase FKBP-type
|
P62942-DOMAIN-20
|
Amino acid modifications |
|
|
|
|
Modified residue
|
9 - 9
|
1
|
Phosphoserine
|
P62942-MOD_RES-9
|
Modified residue
|
53 - 53
|
1
|
N6-acetyllysine
|
P62942-MOD_RES-53
|
|
|
|
|
|
|
|
|
|
|
|
|
1 |
MGVQVETISP |
GDGRTFPKRG |
QTCVVHYTGM |
LEDGKKFDSS |
RDRNKPFKFM |
LGKQEVIRGW |
EEGVAQMSVG |
QRAKLTISPD |
|
81 |
YAYGATGHPG |
IIPPHATLVF |
DVELLKLE |
|
|
|
|
|
|
|
|
|
|
|
|
>sp|P62942|FKB1A_human Peptidyl-prolyl cis-trans isomerase FKBP1A
MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPD
YAYGATGHPGIIPPHATLVFDVELLKLE
|
|
|
| |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Primary source |
Uniprot : D3DVW6
|
Name |
FK506 binding protein 1A, 12kDa, isoform CRA_a [submitted name]
|
Alternative name(s) |
|
Synonym(s) |
|
Organism |
Homo sapiens
|
Length |
108 aa
|
Protein existence |
---
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
General annotation (Comments)
|
top
|
|
|
|
|
|
|
Similarity
|
Belongs to the FKBP-type PPIase family.
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
With
|
Uniprot accession
|
IntAct
|
|
|
|
|
|
|
|
Alternative product(s)
|
top
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Feature key |
Position
|
Length
|
Description
|
Feature identifier
|
|
|
|
|
|
|
|
|
|
|
|
|
1 |
MGVQVETISP |
GDGRTFPKRG |
QTCVVHYTGM |
LEDGKKFDSS |
RDRNKPFKFM |
LGKQEVIRGW |
EEGVAQMSVG |
QRAKLTISPD |
|
81 |
YAYGATGHPG |
IIPPHATLVF |
DVELLKLE |
|
|
|
|
|
|
|
|
|
|
|
|
>sp|D3DVW6|D3DVW6_human FK506 binding protein 1A, 12kDa, isoform CRA_a [submitted name]
MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPD
YAYGATGHPGIIPPHATLVFDVELLKLE
|
|
|
| |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Primary source |
Uniprot : Q0VDC6
|
Name |
FKBP1A protein [submitted name]
|
Alternative name(s) |
|
Synonym(s) |
|
Organism |
Homo sapiens
|
Length |
145 aa
|
Protein existence |
---
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
General annotation (Comments)
|
top
|
|
|
|
|
|
|
Similarity
|
Belongs to the FKBP-type PPIase family.
|
|
|
|
|
|
|
|
|
|
|
|
|
Biological process
|
protein folding [GO:0006457]
|
Molecular function
|
peptidyl-prolyl cis-trans isomerase activity [GO:0003755]
|
|
|
|
|
|
|
|
|
|
|
|
|
With
|
Uniprot accession
|
IntAct
|
|
|
|
|
|
|
|
Alternative product(s)
|
top
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Feature key |
Position
|
Length
|
Description
|
Feature identifier
|
|
|
|
|
|
|
|
|
|
|
|
|
1 |
MGRQRAEGLG |
RAVEPPPGRC |
WSTPPVAPPA |
RSASAAAMGV |
QVETISPGDG |
RTFPKRGQTC |
VVHYTGMLED |
GKKFDSSRDR |
|
81 |
NKPFKFMLGK |
QEVIRGWEEG |
VAQMSVGQRA |
KLTISPDYAY |
GATGHPGIIP |
PHATLVFDVE |
LLKLE |
|
|
|
|
|
|
|
|
|
|
|
|
>sp|Q0VDC6|Q0VDC6_human FKBP1A protein [submitted name]
MGRQRAEGLGRAVEPPPGRCWSTPPVAPPARSASAAAMGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDR
NKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE
|
|
|
| |
|
|
|
|
|
|