(PPP1R15A) protein phosphatase 1, regulatory (inhibitor) subunit 15A [Homo sapiens]
Gene
Transcript(s)
Exon(s)
Protein(s)
Gene
 Accession  10149
 Official symbol  PPP1R15A
 Official name  protein phosphatase 1, regulatory (inhibitor) subunit 15A
 Gene type  gene with protein product
 Organism  Homo sapiens
 Location  Chromosome 19 (NC_000019.9) :  49375648...49379318  (+)
 Map  19q13.2
 Length  3671  nt
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Alternative name(s) and Synynom(s) top
Synonyms GADD34
Alternative name(s) growth arrest and DNA-damage-inducible 34
External Links top
Ensembl ENSG00000087074
Entrez 23645
HGNC 14375
HPRD 06572
Comment top
Summary This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation. [provided by RefSeq].
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Related Articles in PubMed
Genomic Context top
Go to ensembl   www.ensembl.org
Sequence top
FASTA
1  TATAAAAGCC TAGTGGCCAT TGTGTTCGTT GCTCTTATCG GTTCCCATCC CAGTTGTTGA TCTTATGCAA GACGCTGCAC
81  GACCCCGCGC CCGCTTGTCG CCACGGCACT TGAGGCAGCC GGAGATACTC TGAGTTACTC GGAGCCCGAC GCCTGAGGGT
161  GAGATGAACG CGCTGGCCTC CCTAACCGTC CGGACCTGTG ATCGCTTCTG GCAGACCGAA CCGGCGCTCC TGCCCCCGGG
241  GTGACGCGCA GCTCCCAGCC GGTGAGTAAG GGGTCGGAAC GCCTGGGTCC CCACGGGGCT GGGGGCCCGG ATTTAGAAAG
321  GAGAAGGGGT TGGGAGCCTG GAGTCCTGAG CCTGAGGGAG GAGGGATCTG GAAGCCAGAT TCTTGGGTCC CCCGTGAAGG
401  AATCATCTGC CAAGTAGGGG GTCGGGTCAG AATGTTTCAG TCTGCGAGGG AGGAGGGTGT GAGGGTTTGA TTTGTCAATC
481  TTCAGCAGAA TGAGAGAGCT AGGGACTATG ACTTTGTCGC CAAGGGAAGC AAGTAAAGAC TTTTGTTCTT GGTTCTTGGG
561  ACTGGGAGTT CTGCGTCTGA AGAAAGAGAG GGCTGGGGGC TTGGACCCTT GGATCTAAGG CAGAACTAGG GGCTCAGACT
641  CCTGGCTATT GAGAGATAAG AACAGAGCCA AGGGACAGAG ATGGGCGTGG CCGAGATCAG AAAGGAATTT GGGACTCTCG
721  CGTTGCTATT TACAATAGTT GTGTTACTAT TTCCGTTGCT ATGACTCATA GTCACGCCCG GATGCCATCC TCTAAATGGC
801  CCCTAAACTT TATTTTTTTC TCCCCCTTTT CCAGCCCAGA CACATGGCCC CAGGCCAAGC ACCCCATCAG GCTACCCCGT
881  GGAGGGATGC CCACCCTTTC TTCCTCCTGT CCCCAGTGAT GGGCCTCCTC AGCCGCGCCT GGAGCCGCCT GAGGGGCCTG
961  GGACCTCTAG AGCCCTGGCT GGTGGAAGCA GTAAAAGGAG CAGCTCTGGT AGAAGCTGGC CTGGAGGGAG AAGCTAGGAC
1041  TCCTCTGGCA ATCCCCCATA CCCCTTGGGG CAGACGCCCT GAAGAGGAGG CTGAAGACAG TGGAGGCCCT GGAGAGGACA
1121  GAGAAACACT GGGGCTGAAA ACCAGCAGTT CCCTTCCTGA AGCCTGGGGA CTTTTGGATG ATGATGATGG CATGTATGGT
1201  GAGCGAGAGG CAACCAGTGT CCCTAGAGGG CAGGGAAGTC AATTTGCAGA TGGCCAGCGT GCTCCCCTGT CTCCCAGCCT
1281  TCTGATAAGG ACACTGCAAG GTTCTGATAA GAACCCAGGG GAGGAGAAAG CCGAGGAAGA GGGAGTTGCT GAAGAGGAGG
1361  GAGTTAACAA GTTCTCTTAT CCACCATCAC ACCGGGAGTG TTGTCCAGCC GTGGAGGAGG AGGACGATGA AGAAGCTGTA
1441  AAGAAAGAAG CTCACAGAAC CTCTACTTCT GCCTTGTCTC CAGGATCCAA GCCCAGCACT TGGGTGTCTT GCCCAGGGGA
1521  GGAAGAGAAT CAAGCCACGG AGGATAAAAG AACAGAAAGA AGTAAAGGAG CCAGGAAGAC CTCCGTGTCC CCCCGATCTT
1601  CAGGCTCCGA CCCCAGGTCC TGGGAGTATC GTTCAGGAGA GGCGTCCGAG GAGAAGGAGG AAAAGGCACA CAAAGAAACT
1681  GGGAAAGGAG AAGCTGCCCC AGGGCCGCAA TCCTCAGCCC CAGCCCAGAG GCCCCAGCTC AAGTCCTGGT GGTGCCAACC
1761  CAGTGATGAA GAGGAGGGTG AGGTCAAGGC TTTGGGGGCA GCTGAGAAGG ATGGAGAAGC TGAGTGTCCT CCCTGCATCC
1841  CCCCACCAAG TGCCTTCCTG AAGGCCTGGG TGTATTGGCC AGGAGAGGAC ACAGAGGAAG AGGAAGATGA GGAAGAAGAT
1921  GAGGACAGTG ACTCTGGATC AGATGAGGAA GAGGGAGAAG CTGAGGCTTC CTCTTCCACT CCTGCTACAG GTGTCTTCTT
2001  GAAGTCCTGG GTCTATCAGC CAGGAGAGGA CACAGAGGAG GAGGAAGATG AGGACAGTGA TACAGGATCA GCCGAGGATG
2081  AAAGAGAAGC TGAGACTTCT GCTTCCACAC CCCCTGCAAG TGCTTTCTTG AAGGCCTGGG TGTATCGGCC AGGAGAGGAC
2161  ACGGAGGAGG AGGAAGATGA GGATGTGGAT AGTGAGGATA AGGAAGATGA TTCAGAAGCA GCCTTGGGAG AAGCTGAGTC
2241  AGACCCACAT CCCTCCCACC CGGACCAGAG GGCCCACTTC AGGGGCTGGG GATATCGACC TGGAAAAGAG ACAGAGGAAG
2321  AGGAAGCTGC TGAGGACTGG GGAGAAGCTG AGCCCTGCCC CTTCCGAGTG GCCATCTATG TACCTGGAGA GAAGCCACCG
2401  CCTCCCTGGG CTCCTCCTAG GCTGCCCCTC CGACTGCAAA GGCGGCTCAA GCGCCCAGAA ACCCCTACTC ATGATCCGGA
2481  CCCTGAGACT CCCCTAAAGG CCAGAAAGGT AGGTGCTGAG AGCCCAGATT CTATTTTTTT TTTTTTTTTA ATTGAGTTGG
2561  AGTCTTGGGC TGTCACCCAG GCTGGAGTGC AGCGGCATGA TCTTGGCTCA CTGCCAACCT CTGCCGCCCA AGTTCAGGCG
2641  ATTCTCGTGC CTCAGCCTCC AGAGTATCTG GGATTACAGG CGCATGACAC CACACCCAGC TAATTTTTTT TGTATTTTTA
2721  GTAGAGACGG GGGTTTTGCC ATGTTGGCCA GGCTGGTCTC AAACTCCTGA CATCACGTGA TCCACCCATC TCAGCCTCCC
2801  AAAGTGCTGG GATTACAGGC GTGAGCTACC ACATCTGGCT GAGAGCCCAG ATTCTTGAGT CTTAGAAAGA AAGGGGGCTG
2881  GGGGCCGAGA CTTCTGGGTC CCTGTATGTT GCAGAGGGTT GCATGTCATC TCCATGGAGA AGGCTGTGTA CGCTGTCACG
2961  CAATCCCTTG TAAGAGGCCA GGCCCCTGGG GGAGGAGGGA GCAGCTGTGG CTCACAGCAG CCCCAGGAAA CCACCTCTTC
3041  CTTCAGTGAG TCAGATAGAT AGAGAATCCC GTGACAGTGA CAGGCAAGTG ACTAGCCAGA TAGAAAGCAT TTTTGTGTAA
3121  TAACTAATTT TTGTTTGCTT CTCTCTCTCT CTTCCCCGCC CTCCCCATCC GGATTCCCGT GGCTGTGTGC ATCTCCTGCC
3201  TGTGTCCCCA TGTCTGCCCG CAGGTGCGCT TCTCCGAGAA GGTCACTGTC CATTTCCTGG CTGTCTGGGC AGGGCCGGCC
3281  CAGGCCGCCC GCCAGGGCCC CTGGGAGCAG CTTGCTCGGG ATCGCAGCCG CTTCGCACGC CGCATCACCC AGGCCCAGGA
3361  GGAGCTGAGC CCCTGCCTCA CCCCTGCTGC CCGGGCCAGA GCCTGGGCAC GCCTCAGGAA CCCACCTTTA GCCCCCATCC
3441  CTGCCCTCAC CCAGACCTTG CCTTCCTCCT CTGTCCCTTC GTCCCCAGTC CAGACCACGC CCTTGAGCCA AGCTGTGGCC
3521  ACACCTTCCC GCTCGTCTGC TGCTGCAGCG GCTGCCCTGG ACCTCAGTGG GAGGCGTGGC TGAGACCAAC TGGTTTGCCT
3601  ATAATTTATT AACTATTTAT TTTTTCTAAG TGTGGGTTTA TATAAGGAAT AAAGCCTTTT GATTTGTAGC G
>ref|Gene_ID:23645|PPP1R15A|NC_000019.9:49375648...49379318 (+)
TATAAAAGCCTAGTGGCCATTGTGTTCGTTGCTCTTATCGGTTCCCATCCCAGTTGTTGATCTTATGCAAGACGCTGCAC
GACCCCGCGCCCGCTTGTCGCCACGGCACTTGAGGCAGCCGGAGATACTCTGAGTTACTCGGAGCCCGACGCCTGAGGGT
GAGATGAACGCGCTGGCCTCCCTAACCGTCCGGACCTGTGATCGCTTCTGGCAGACCGAACCGGCGCTCCTGCCCCCGGG
GTGACGCGCAGCTCCCAGCCGGTGAGTAAGGGGTCGGAACGCCTGGGTCCCCACGGGGCTGGGGGCCCGGATTTAGAAAG
GAGAAGGGGTTGGGAGCCTGGAGTCCTGAGCCTGAGGGAGGAGGGATCTGGAAGCCAGATTCTTGGGTCCCCCGTGAAGG
AATCATCTGCCAAGTAGGGGGTCGGGTCAGAATGTTTCAGTCTGCGAGGGAGGAGGGTGTGAGGGTTTGATTTGTCAATC
TTCAGCAGAATGAGAGAGCTAGGGACTATGACTTTGTCGCCAAGGGAAGCAAGTAAAGACTTTTGTTCTTGGTTCTTGGG
ACTGGGAGTTCTGCGTCTGAAGAAAGAGAGGGCTGGGGGCTTGGACCCTTGGATCTAAGGCAGAACTAGGGGCTCAGACT
CCTGGCTATTGAGAGATAAGAACAGAGCCAAGGGACAGAGATGGGCGTGGCCGAGATCAGAAAGGAATTTGGGACTCTCG
CGTTGCTATTTACAATAGTTGTGTTACTATTTCCGTTGCTATGACTCATAGTCACGCCCGGATGCCATCCTCTAAATGGC
CCCTAAACTTTATTTTTTTCTCCCCCTTTTCCAGCCCAGACACATGGCCCCAGGCCAAGCACCCCATCAGGCTACCCCGT
GGAGGGATGCCCACCCTTTCTTCCTCCTGTCCCCAGTGATGGGCCTCCTCAGCCGCGCCTGGAGCCGCCTGAGGGGCCTG
GGACCTCTAGAGCCCTGGCTGGTGGAAGCAGTAAAAGGAGCAGCTCTGGTAGAAGCTGGCCTGGAGGGAGAAGCTAGGAC
TCCTCTGGCAATCCCCCATACCCCTTGGGGCAGACGCCCTGAAGAGGAGGCTGAAGACAGTGGAGGCCCTGGAGAGGACA
GAGAAACACTGGGGCTGAAAACCAGCAGTTCCCTTCCTGAAGCCTGGGGACTTTTGGATGATGATGATGGCATGTATGGT
GAGCGAGAGGCAACCAGTGTCCCTAGAGGGCAGGGAAGTCAATTTGCAGATGGCCAGCGTGCTCCCCTGTCTCCCAGCCT
TCTGATAAGGACACTGCAAGGTTCTGATAAGAACCCAGGGGAGGAGAAAGCCGAGGAAGAGGGAGTTGCTGAAGAGGAGG
GAGTTAACAAGTTCTCTTATCCACCATCACACCGGGAGTGTTGTCCAGCCGTGGAGGAGGAGGACGATGAAGAAGCTGTA
AAGAAAGAAGCTCACAGAACCTCTACTTCTGCCTTGTCTCCAGGATCCAAGCCCAGCACTTGGGTGTCTTGCCCAGGGGA
GGAAGAGAATCAAGCCACGGAGGATAAAAGAACAGAAAGAAGTAAAGGAGCCAGGAAGACCTCCGTGTCCCCCCGATCTT
CAGGCTCCGACCCCAGGTCCTGGGAGTATCGTTCAGGAGAGGCGTCCGAGGAGAAGGAGGAAAAGGCACACAAAGAAACT
GGGAAAGGAGAAGCTGCCCCAGGGCCGCAATCCTCAGCCCCAGCCCAGAGGCCCCAGCTCAAGTCCTGGTGGTGCCAACC
CAGTGATGAAGAGGAGGGTGAGGTCAAGGCTTTGGGGGCAGCTGAGAAGGATGGAGAAGCTGAGTGTCCTCCCTGCATCC
CCCCACCAAGTGCCTTCCTGAAGGCCTGGGTGTATTGGCCAGGAGAGGACACAGAGGAAGAGGAAGATGAGGAAGAAGAT
GAGGACAGTGACTCTGGATCAGATGAGGAAGAGGGAGAAGCTGAGGCTTCCTCTTCCACTCCTGCTACAGGTGTCTTCTT
GAAGTCCTGGGTCTATCAGCCAGGAGAGGACACAGAGGAGGAGGAAGATGAGGACAGTGATACAGGATCAGCCGAGGATG
AAAGAGAAGCTGAGACTTCTGCTTCCACACCCCCTGCAAGTGCTTTCTTGAAGGCCTGGGTGTATCGGCCAGGAGAGGAC
ACGGAGGAGGAGGAAGATGAGGATGTGGATAGTGAGGATAAGGAAGATGATTCAGAAGCAGCCTTGGGAGAAGCTGAGTC
AGACCCACATCCCTCCCACCCGGACCAGAGGGCCCACTTCAGGGGCTGGGGATATCGACCTGGAAAAGAGACAGAGGAAG
AGGAAGCTGCTGAGGACTGGGGAGAAGCTGAGCCCTGCCCCTTCCGAGTGGCCATCTATGTACCTGGAGAGAAGCCACCG
CCTCCCTGGGCTCCTCCTAGGCTGCCCCTCCGACTGCAAAGGCGGCTCAAGCGCCCAGAAACCCCTACTCATGATCCGGA
CCCTGAGACTCCCCTAAAGGCCAGAAAGGTAGGTGCTGAGAGCCCAGATTCTATTTTTTTTTTTTTTTTAATTGAGTTGG
AGTCTTGGGCTGTCACCCAGGCTGGAGTGCAGCGGCATGATCTTGGCTCACTGCCAACCTCTGCCGCCCAAGTTCAGGCG
ATTCTCGTGCCTCAGCCTCCAGAGTATCTGGGATTACAGGCGCATGACACCACACCCAGCTAATTTTTTTTGTATTTTTA
GTAGAGACGGGGGTTTTGCCATGTTGGCCAGGCTGGTCTCAAACTCCTGACATCACGTGATCCACCCATCTCAGCCTCCC
AAAGTGCTGGGATTACAGGCGTGAGCTACCACATCTGGCTGAGAGCCCAGATTCTTGAGTCTTAGAAAGAAAGGGGGCTG
GGGGCCGAGACTTCTGGGTCCCTGTATGTTGCAGAGGGTTGCATGTCATCTCCATGGAGAAGGCTGTGTACGCTGTCACG
CAATCCCTTGTAAGAGGCCAGGCCCCTGGGGGAGGAGGGAGCAGCTGTGGCTCACAGCAGCCCCAGGAAACCACCTCTTC
CTTCAGTGAGTCAGATAGATAGAGAATCCCGTGACAGTGACAGGCAAGTGACTAGCCAGATAGAAAGCATTTTTGTGTAA
TAACTAATTTTTGTTTGCTTCTCTCTCTCTCTTCCCCGCCCTCCCCATCCGGATTCCCGTGGCTGTGTGCATCTCCTGCC
TGTGTCCCCATGTCTGCCCGCAGGTGCGCTTCTCCGAGAAGGTCACTGTCCATTTCCTGGCTGTCTGGGCAGGGCCGGCC
CAGGCCGCCCGCCAGGGCCCCTGGGAGCAGCTTGCTCGGGATCGCAGCCGCTTCGCACGCCGCATCACCCAGGCCCAGGA
GGAGCTGAGCCCCTGCCTCACCCCTGCTGCCCGGGCCAGAGCCTGGGCACGCCTCAGGAACCCACCTTTAGCCCCCATCC
CTGCCCTCACCCAGACCTTGCCTTCCTCCTCTGTCCCTTCGTCCCCAGTCCAGACCACGCCCTTGAGCCAAGCTGTGGCC
ACACCTTCCCGCTCGTCTGCTGCTGCAGCGGCTGCCCTGGACCTCAGTGGGAGGCGTGGCTGAGACCAACTGGTTTGCCT
ATAATTTATTAACTATTTATTTTTTCTAAGTGTGGGTTTATATAAGGAATAAAGCCTTTTGATTTGTAGCG