(HSPA8) heat shock 70kDa protein 8 [Homo sapiens]
Gene
Transcript(s)
Exon(s)
Protein(s)
Gene
 Accession  6113
 Official symbol  HSPA8
 Official name  heat shock 70kDa protein 8
 Gene type  gene with protein product
 Organism  Homo sapiens
 Location  Chromosome 11 (NC_000011.9) :  122928199...122932843  (-)
 Map  11q24.1
 Length  4645  nt
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Alternative name(s) and Synynom(s) top
Synonyms NIP71; MGC29929; MGC131511; LAP1; HSP71; HSC54; HSPA10; HSP73; HSC71; HSC70
Alternative name(s) N-myristoyltransferase inhibitor protein 71; LPS-associated protein 1; lipopolysaccharide-associated protein 1; constitutive heat shock protein 70; heat shock cognate protein 54; heat shock 70kd protein 10; heat shock cognate protein, 71-kDa; heat shock 70kD protein 8
External Links top
Ensembl ENSG00000109971
Entrez 3312
HGNC 5241
HPRD 07205
Comment top
Summary The product encoded by this gene belongs to the heat shock protein 70 family which contains both heat-inducible and constitutively expressed members. The latter are called heat-shock cognate proteins. This gene encodes a heat-shock cognate protein. This protein binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Two alternatively spliced variants have been characterized to date. [provided by RefSeq].
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Related Articles in PubMed
Genomic Context top
Go to ensembl   www.ensembl.org
Sequence top
FASTA
1  TCATTGAACT CGCCTGCAGC TCTTGGGTTT TTTGTGGCTT CCTTCGTTAT TGGAGCCAGG CCTACACCCC AGGTAAAACC
81  TCTGCTCAAG AGTTGGGTTG TGGGTCTGGG AGCGTGCAGC CTCCACACAG GCCTGTTGGG CTTGCTGAGG CTTGGGGGTT
161  CTGAGAATCT CGTCGAGGCG AGTGTGCGGC TCCTTCTACC GGCTTAAAGG GCCTCAGTTT TCGGTGGGAT GGCAGCGGTA
241  TTTGGTTGCA GCCGGCAGGA CGGAAATGTA GGGAGTGGGC CGCAGTGGCC CCAGGGGAGG CTGGGAGACG CCCGGCGGCC
321  GCGTGGCGGG GGAGGGTTGC TGCATCGGTT TGCCTGGCGC GCGGGGAAGT GGAGCCAGCG TTTTCTTTCA CCCAGTTCCC
401  TGCTTAGTCC AGTCCCACCG TGGTTCTTCA GAGCTGTTCT TGGCGTGCTT CCAGTATGGG GGTACATTCC GGAGTAGTTA
481  AAAGCCCGTT GACTCCCGGG GGCACTGGCA CCTGGCGAGG GAGGGGAACA GACAGTGCTC AGTTCGGGGT AAGACCACGT
561  GTTGAGCAAC GCCCCACGCC GTCTGGGTAG ATGGGTCCTT CATCTAGGGC GTGCTCTGCT GCGGTTGGCA CGGCAACCTG
641  GACTGCAGCA CTAGTTCTGG ACCTCGCGCG TGCTTAGACA GGAGGTGATG GGCACTATTA CCTCTTGGCA GTGGCCATAC
721  GTTTTTCCTG GTTAAGTGTT CTGTTAAGGG ATGAGGGAAA TATTTTGATT AATTGAATTT TTAAACCAGA TTTTTCTTTT
801  TTTCAGCAAC CATGTCCAAG GGACCTGCAG TTGGTATTGA TCTTGGCACC ACCTACTCTT GTGTGGGTGT TTTCCAGCAC
881  GGAAAAGTCG AGATAATTGC CAATGATCAG GGAAACCGAA CCACTCCAAG CTATGTCGCC TTTACGGACA CTGAACGGTT
961  GATCGGTGAT GCCGCAAAGA ATCAAGTTGC AATGAACCCC ACCAACACAG TTTTTGGTGA GTTCCTAATT TTAAATGACA
1041  GAACAAATAT AACAGGGCTA GGAAGCACAA AAGTTTATGA AACGTGAGGA GGGAACTTTT TGATTTTAGA AAAACTGAGC
1121  TGAGAGACTT GTTATCAAGT CTGTTATAAA ACAGGTTGTA GAAACCTTTC AGGCTGAAAT CTGGATAACG TAGGAGGTTG
1201  AAGTTTGAAC CTTTGCTACC TATATGGTAG TTGAATTCAC CTACCTATGA ACTGTTAGGT ATTTGAGTAA TCATGGACTT
1281  GAGTTTTATC AGAAGAGCTA TGAAATTGAA AGTGTTTTCA TTTGACACCT TTTACAGATG CCAAACGTCT GATTGGACGC
1361  AGATTTGATG ATGCTGTTGT CCAGTCTGAT ATGAAACATT GGCCCTTTAT GGTGGTGAAT GATGCTGGCA GGCCCAAGGT
1441  CCAAGTAGAA TACAAGGGAG AGACCAAAAG CTTCTATCCA GAGGAGGTGT CTTCTATGGT TCTGACAAAG ATGAAGGAAA
1521  TTGCAGAAGC CTACCTTGGG AAGGTGAGGT TGGTTTTTCA GTATGGGGTG CATTCCGGAG TAGTTAAAAG CCCGATGACT
1601  CCCGGGGGCA CTGGCACCTG GCGAGGGAGG GGAACAGATG GGGCTCAGCT CAGGGTTAAG ACCACGTGCC CAACAGTGCC
1681  CTAGGCTCTC TAGGTAGATG GGTCTGTCAA CACCAGAAAC CAGTGAATCT TGACAATTAC ACAGTAATTT ACATTTTGGT
1761  GGGGGGGGTG CTCCAGCTGT TCTTTCACCA GCATTAATCC ATTTGCTGGA GTTTGCATAT ATGTAAGTAT AATAGTTACC
1841  AATCTGTGGT CTTTTCCTTA TTCCTAGACT GTTACCAATG CTGTGGTCAC AGTGCCAGCT TACTTTAATG ACTCTCAGCG
1921  TCAGGCTACC AAAGATGCTG GAACTATTGC TGGTCTCAAT GTACTTAGAA TTATTAATGA GCCAACTGCT GCTGCTATTG
2001  CTTACGGCTT AGACAAAAAG GTATGTACCA TTTGTGATGC AAGTTCGGAT TATTTTAAGA TTAATTTGAT CCATCGTAAA
2081  TTTAAATGAG ATTGTTTTTA ACGGCAGGTT GGAGCAGAAA GAAACGTGCT CATCTTTGAC CTGGGAGGTG GCACTTTTGA
2161  TGTGTCAATC CTCACTATTG AGGATGGAAT CTTTGAGGTC AAGTCTACAG CTGGAGACAC CCACTTGGGT GGAGAAGATT
2241  TTGACAACCG AATGGTCAAC CATTTTATTG CTGAGTTTAA GCGCAAGCAT AAGAAGGACA TCAGTGAGAA CAAGAGAGCT
2321  GTAAGACGCC TCCGTACTGC TTGTGAACGT GCTAAGCGTA CCCTCTCTTC CAGCACCCAG GCCAGTATTG AGATCGATTC
2401  TCTCTATGAA GGAATCGACT TCTATACCTC CATTACCCGT GCCCGATTTG AAGAACTGAA TGCTGACCTG TTCCGTGGCA
2481  CCCTGGACCC AGTAGAGAAA GCCCTTCGAG ATGCCAAACT AGACAAGTCA CAGATTCATG ATATTGTCCT GGTTGGTGGT
2561  TCTACTCGTA TCCCCAAGAT TCAGAAGCTT CTCCAAGACT TCTTCAATGG AAAAGAACTG AATAAGAGCA TCAACCCTGA
2641  TGAAGCTGTT GCTTATGGTG CAGGTAACAA TGGTATCTCA ATTAACCCTA AAGGCAGGCA GGCCCAAGGT GACTCGCTGT
2721  GATGAGTGAT TGTTAAACAT TCGTAGTTTC CACCAAAAGC TTGGCTAATG ATGGCAACAC CTTCCTTGGA TGTCTGAGCG
2801  AGTGATAGTT AAAACAGGAG CTATGTACTG GGTTTTCTTT TAACTTCTTT TAACGTTAAC TTTTTGTTTG CTAGCTGTCC
2881  AGGCAGCCAT CTTGTCTGGA GACAAGTCTG AGAATGTTCA AGATTTGCTG CTCTTGGATG TCACTCCTCT TTCCCTTGGT
2961  ATTGAAACTG CTGGTGGAGT CATGACTGTC CTCATCAAGC GTAATACCAC CATTCCTACC AAGCAGACAC AGACCTTCAC
3041  TACCTATTCT GACAACCAGC CTGGTGTGCT TATTCAGGTA TGTTTCTGTA CTTCTCTTGT TTGGCTTACT GATAACAGAT
3121  AAAGGGAAGT CTTGACTGAC TCGCTATGAT GATGGATTCC AAAACCATTC GTAGTTTCCA CCAGAAAGTC TTATGTTGGC
3201  CAGTTCCTTC CTTGGATGTT TGAGCGACCA TTCTTCCTTA GCAGGACCCT AGCACTGTCA CAGACCTGGA GTCCATTGTA
3281  GTAATTTGTT TTATTTCCTA CCAAGGTTTA TGAAGGCGAG CGTGCCATGA CAAAGGATAA CAACCTGCTT GGCAAGTTTG
3361  AACTCACAGG CATACCTCCT GCACCCCGAG GTGTTCCTCA GATTGAAGTC ACTTTTGACA TTGATGCCAA TGGTATACTC
3441  AATGTCTCTG CTGTGGACAA GAGTACGGGA AAAGAGAACA AGATTACTAT CACTAATGAC AAGGGTAAGG AGGCACTGTC
3521  ATCTGGTCTT GACAGGGATA ATGGTATTTC AATTGAGTTA CTGGTGCCTA AGGGCGTCTA GCTAAGAGAA ACTAGAGTTA
3601  CACATACACA GGTAATTTAA GGCTTTTACT TAGAGTTAAT TTCTTTCCTA GGCCGTTTGA GCAAGGAAGA CATTGAACGT
3681  ATGGTCCAGG AAGCTGAGAA GTACAAAGCT GAAGATGAGA AGCAGAGGGA CAAGGTGTCA TCCAAGAATT CACTTGAGTC
3761  CTATGCCTTC AACATGAAAG CAACTGTTGA AGATGAGAAA CTTCAAGGCA AGATTAACGA TGAGGACAAA CAGAAGATTC
3841  TGGACAAGTG TAATGAAATT ATCAACTGGC TTGATAAGAA TCAGGTTTGT GTTTTTTTTT TTTTTTTTTC CTCCCCCACT
3921  CAATGGAGGG GAAGGGGATG GTAAACCAAG CTTGAGCTGG ATTTCAGTGT AGGGTCACAA TGATGAATGG TCCAAAACAT
4001  TCGCGGTTTC CACCAGAATT CAAGGTGTTG GCAACTACCT TCCTTGGATG TCTGAGTGAC CCAAGATGTT AAGGAAGAAT
4081  AAGGCCCTAT TTTAATGTTG GTAGTGGCCC TCTTGTAAGA GTTTGCGCCA GACTTTTAGT ATCAGATTGC GTCAGGGAGA
4161  AAGAAGGGTT ATTAACATTA AAAGAACTTG CAGTAATTCC TTTTTCTCTT CCTCAGACTG CTGAGAAGGA AGAATTTGAA
4241  CATCAACAGA AAGAGCTGGA GAAAGTTTGC AACCCCATCA TCACCAAGCT GTACCAGAGT GCAGGAGGCA TGCCAGGAGG
4321  AATGCCTGGG GGATTTCCTG GTGGTGGAGC TCCTCCCTCT GGTGGTGCTT CCTCAGGGCC CACCATTGAA GAGGTTGATT
4401  AAGCCAACCA AGTGTAGATG TAGCATTGTT CCACACATTT AAAACATTTG AAGGACCTAA ATTCGTAGCA AATTCTGTGG
4481  CAGTTTTAAA AAGTTAAGCT GCTATAGTAA GTTACTGGGC ATTCTCAATA CTTGAATATG GAACATATGC ACAGGGGAAG
4561  GAAATAACAT TGCACTTTAT AAACACTGTA TTGTAAGTGG AAAATGCAAT GTCTTAAATA AAACTATTTA AAATTGGCAC
4641  CATAC
>ref|Gene_ID:3312|HSPA8|NC_000011.9:122928199...122932843 (-)
TCATTGAACTCGCCTGCAGCTCTTGGGTTTTTTGTGGCTTCCTTCGTTATTGGAGCCAGGCCTACACCCCAGGTAAAACC
TCTGCTCAAGAGTTGGGTTGTGGGTCTGGGAGCGTGCAGCCTCCACACAGGCCTGTTGGGCTTGCTGAGGCTTGGGGGTT
CTGAGAATCTCGTCGAGGCGAGTGTGCGGCTCCTTCTACCGGCTTAAAGGGCCTCAGTTTTCGGTGGGATGGCAGCGGTA
TTTGGTTGCAGCCGGCAGGACGGAAATGTAGGGAGTGGGCCGCAGTGGCCCCAGGGGAGGCTGGGAGACGCCCGGCGGCC
GCGTGGCGGGGGAGGGTTGCTGCATCGGTTTGCCTGGCGCGCGGGGAAGTGGAGCCAGCGTTTTCTTTCACCCAGTTCCC
TGCTTAGTCCAGTCCCACCGTGGTTCTTCAGAGCTGTTCTTGGCGTGCTTCCAGTATGGGGGTACATTCCGGAGTAGTTA
AAAGCCCGTTGACTCCCGGGGGCACTGGCACCTGGCGAGGGAGGGGAACAGACAGTGCTCAGTTCGGGGTAAGACCACGT
GTTGAGCAACGCCCCACGCCGTCTGGGTAGATGGGTCCTTCATCTAGGGCGTGCTCTGCTGCGGTTGGCACGGCAACCTG
GACTGCAGCACTAGTTCTGGACCTCGCGCGTGCTTAGACAGGAGGTGATGGGCACTATTACCTCTTGGCAGTGGCCATAC
GTTTTTCCTGGTTAAGTGTTCTGTTAAGGGATGAGGGAAATATTTTGATTAATTGAATTTTTAAACCAGATTTTTCTTTT
TTTCAGCAACCATGTCCAAGGGACCTGCAGTTGGTATTGATCTTGGCACCACCTACTCTTGTGTGGGTGTTTTCCAGCAC
GGAAAAGTCGAGATAATTGCCAATGATCAGGGAAACCGAACCACTCCAAGCTATGTCGCCTTTACGGACACTGAACGGTT
GATCGGTGATGCCGCAAAGAATCAAGTTGCAATGAACCCCACCAACACAGTTTTTGGTGAGTTCCTAATTTTAAATGACA
GAACAAATATAACAGGGCTAGGAAGCACAAAAGTTTATGAAACGTGAGGAGGGAACTTTTTGATTTTAGAAAAACTGAGC
TGAGAGACTTGTTATCAAGTCTGTTATAAAACAGGTTGTAGAAACCTTTCAGGCTGAAATCTGGATAACGTAGGAGGTTG
AAGTTTGAACCTTTGCTACCTATATGGTAGTTGAATTCACCTACCTATGAACTGTTAGGTATTTGAGTAATCATGGACTT
GAGTTTTATCAGAAGAGCTATGAAATTGAAAGTGTTTTCATTTGACACCTTTTACAGATGCCAAACGTCTGATTGGACGC
AGATTTGATGATGCTGTTGTCCAGTCTGATATGAAACATTGGCCCTTTATGGTGGTGAATGATGCTGGCAGGCCCAAGGT
CCAAGTAGAATACAAGGGAGAGACCAAAAGCTTCTATCCAGAGGAGGTGTCTTCTATGGTTCTGACAAAGATGAAGGAAA
TTGCAGAAGCCTACCTTGGGAAGGTGAGGTTGGTTTTTCAGTATGGGGTGCATTCCGGAGTAGTTAAAAGCCCGATGACT
CCCGGGGGCACTGGCACCTGGCGAGGGAGGGGAACAGATGGGGCTCAGCTCAGGGTTAAGACCACGTGCCCAACAGTGCC
CTAGGCTCTCTAGGTAGATGGGTCTGTCAACACCAGAAACCAGTGAATCTTGACAATTACACAGTAATTTACATTTTGGT
GGGGGGGGTGCTCCAGCTGTTCTTTCACCAGCATTAATCCATTTGCTGGAGTTTGCATATATGTAAGTATAATAGTTACC
AATCTGTGGTCTTTTCCTTATTCCTAGACTGTTACCAATGCTGTGGTCACAGTGCCAGCTTACTTTAATGACTCTCAGCG
TCAGGCTACCAAAGATGCTGGAACTATTGCTGGTCTCAATGTACTTAGAATTATTAATGAGCCAACTGCTGCTGCTATTG
CTTACGGCTTAGACAAAAAGGTATGTACCATTTGTGATGCAAGTTCGGATTATTTTAAGATTAATTTGATCCATCGTAAA
TTTAAATGAGATTGTTTTTAACGGCAGGTTGGAGCAGAAAGAAACGTGCTCATCTTTGACCTGGGAGGTGGCACTTTTGA
TGTGTCAATCCTCACTATTGAGGATGGAATCTTTGAGGTCAAGTCTACAGCTGGAGACACCCACTTGGGTGGAGAAGATT
TTGACAACCGAATGGTCAACCATTTTATTGCTGAGTTTAAGCGCAAGCATAAGAAGGACATCAGTGAGAACAAGAGAGCT
GTAAGACGCCTCCGTACTGCTTGTGAACGTGCTAAGCGTACCCTCTCTTCCAGCACCCAGGCCAGTATTGAGATCGATTC
TCTCTATGAAGGAATCGACTTCTATACCTCCATTACCCGTGCCCGATTTGAAGAACTGAATGCTGACCTGTTCCGTGGCA
CCCTGGACCCAGTAGAGAAAGCCCTTCGAGATGCCAAACTAGACAAGTCACAGATTCATGATATTGTCCTGGTTGGTGGT
TCTACTCGTATCCCCAAGATTCAGAAGCTTCTCCAAGACTTCTTCAATGGAAAAGAACTGAATAAGAGCATCAACCCTGA
TGAAGCTGTTGCTTATGGTGCAGGTAACAATGGTATCTCAATTAACCCTAAAGGCAGGCAGGCCCAAGGTGACTCGCTGT
GATGAGTGATTGTTAAACATTCGTAGTTTCCACCAAAAGCTTGGCTAATGATGGCAACACCTTCCTTGGATGTCTGAGCG
AGTGATAGTTAAAACAGGAGCTATGTACTGGGTTTTCTTTTAACTTCTTTTAACGTTAACTTTTTGTTTGCTAGCTGTCC
AGGCAGCCATCTTGTCTGGAGACAAGTCTGAGAATGTTCAAGATTTGCTGCTCTTGGATGTCACTCCTCTTTCCCTTGGT
ATTGAAACTGCTGGTGGAGTCATGACTGTCCTCATCAAGCGTAATACCACCATTCCTACCAAGCAGACACAGACCTTCAC
TACCTATTCTGACAACCAGCCTGGTGTGCTTATTCAGGTATGTTTCTGTACTTCTCTTGTTTGGCTTACTGATAACAGAT
AAAGGGAAGTCTTGACTGACTCGCTATGATGATGGATTCCAAAACCATTCGTAGTTTCCACCAGAAAGTCTTATGTTGGC
CAGTTCCTTCCTTGGATGTTTGAGCGACCATTCTTCCTTAGCAGGACCCTAGCACTGTCACAGACCTGGAGTCCATTGTA
GTAATTTGTTTTATTTCCTACCAAGGTTTATGAAGGCGAGCGTGCCATGACAAAGGATAACAACCTGCTTGGCAAGTTTG
AACTCACAGGCATACCTCCTGCACCCCGAGGTGTTCCTCAGATTGAAGTCACTTTTGACATTGATGCCAATGGTATACTC
AATGTCTCTGCTGTGGACAAGAGTACGGGAAAAGAGAACAAGATTACTATCACTAATGACAAGGGTAAGGAGGCACTGTC
ATCTGGTCTTGACAGGGATAATGGTATTTCAATTGAGTTACTGGTGCCTAAGGGCGTCTAGCTAAGAGAAACTAGAGTTA
CACATACACAGGTAATTTAAGGCTTTTACTTAGAGTTAATTTCTTTCCTAGGCCGTTTGAGCAAGGAAGACATTGAACGT
ATGGTCCAGGAAGCTGAGAAGTACAAAGCTGAAGATGAGAAGCAGAGGGACAAGGTGTCATCCAAGAATTCACTTGAGTC
CTATGCCTTCAACATGAAAGCAACTGTTGAAGATGAGAAACTTCAAGGCAAGATTAACGATGAGGACAAACAGAAGATTC
TGGACAAGTGTAATGAAATTATCAACTGGCTTGATAAGAATCAGGTTTGTGTTTTTTTTTTTTTTTTTTCCTCCCCCACT
CAATGGAGGGGAAGGGGATGGTAAACCAAGCTTGAGCTGGATTTCAGTGTAGGGTCACAATGATGAATGGTCCAAAACAT
TCGCGGTTTCCACCAGAATTCAAGGTGTTGGCAACTACCTTCCTTGGATGTCTGAGTGACCCAAGATGTTAAGGAAGAAT
AAGGCCCTATTTTAATGTTGGTAGTGGCCCTCTTGTAAGAGTTTGCGCCAGACTTTTAGTATCAGATTGCGTCAGGGAGA
AAGAAGGGTTATTAACATTAAAAGAACTTGCAGTAATTCCTTTTTCTCTTCCTCAGACTGCTGAGAAGGAAGAATTTGAA
CATCAACAGAAAGAGCTGGAGAAAGTTTGCAACCCCATCATCACCAAGCTGTACCAGAGTGCAGGAGGCATGCCAGGAGG
AATGCCTGGGGGATTTCCTGGTGGTGGAGCTCCTCCCTCTGGTGGTGCTTCCTCAGGGCCCACCATTGAAGAGGTTGATT
AAGCCAACCAAGTGTAGATGTAGCATTGTTCCACACATTTAAAACATTTGAAGGACCTAAATTCGTAGCAAATTCTGTGG
CAGTTTTAAAAAGTTAAGCTGCTATAGTAAGTTACTGGGCATTCTCAATACTTGAATATGGAACATATGCACAGGGGAAG
GAAATAACATTGCACTTTATAAACACTGTATTGTAAGTGGAAAATGCAATGTCTTAAATAAAACTATTTAAAATTGGCAC
CATAC