(BIRC5) baculoviral IAP repeat-containing 5 [Homo sapiens] |
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Gene
Transcript(s)
Exon(s)
Protein(s)
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Accession
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9527
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Official symbol
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BIRC5
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Official name
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baculoviral IAP repeat-containing 5
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Gene type
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gene with protein product
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Organism
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Homo sapiens
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Location
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Chromosome 17 (NC_000017.10) : 76210276...76221715 (+)
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Map
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17q25
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Length
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11440 nt
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NM_001168.2
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BIRC5, mRNA isoform 1
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NM_001012270.1
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BIRC5, mRNA isoform 2
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NM_001012271.1
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BIRC5, mRNA isoform 3
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Accession
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Name
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Organism
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Length
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O15392
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Baculoviral IAP repeat-containing protein 5
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Homo sapiens
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142 aa
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Synonyms |
EPR-1; API4
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Alternative name(s) |
survivin variant 3 alpha; survivin; apoptosis inhibitor 4
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Summary |
This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined. [provided by RefSeq].
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Related Articles in PubMed
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Go to ensembl
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1 |
TCCCAGAAGG |
CCGCGGGGGG |
TGGACCGCCT |
AAGAGGGCGT |
GCGCTCCCGA |
CATGCCCCGC |
GGCGCGCCAT |
TAACCGCCAG |
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81 |
ATTTGAATCG |
CGGGACCCGT |
TGGCAGAGGT |
GGCGGCGGCG |
GCATGGGTGC |
CCCGACGTTG |
CCCCCTGCCT |
GGCAGCCCTT |
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161 |
TCTCAAGGAC |
CACCGCATCT |
CTACATTCAA |
GAACTGGCCC |
TTCTTGGAGG |
GCTGCGCCTG |
CACCCCGGAG |
CGGGTGAGAC |
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241 |
TGCCCGGCCT |
CCTGGGGTCC |
CCCACGCCCG |
CCTTGCCCTG |
TCCCTAGCGA |
GGCCACTGTG |
ACTGGGCCTC |
GGGGGTACAA |
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321 |
GCCGCCCTCC |
CCTCCCCGTC |
CTGTCCCCAG |
CGAGGCCACT |
GTGGCTGGGC |
CCCTTGGGTC |
CAGGCCGGCC |
TCCCCTCCCT |
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401 |
GCTTTGTCCC |
CATCGAGGCC |
TTTGTGGCTG |
GGCCTCGGGG |
TTCCGGGCTG |
CCACGTCCAC |
TCACGAGCTG |
TGCTGTCCCT |
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481 |
TGCAGATGGC |
CGAGGCTGGC |
TTCATCCACT |
GCCCCACTGA |
GAACGAGCCA |
GACTTGGCCC |
AGTGTTTCTT |
CTGCTTCAAG |
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561 |
GAGCTGGAAG |
GCTGGGAGCC |
AGATGACGAC |
CCCATGTAAG |
TCTTCTCTGG |
CCAGCCTCGA |
TGGGCTTTGT |
TTTGAACTGA |
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641 |
GTTGTCAAAA |
GATTTGAGTT |
GCAAAGACAC |
TTAGTATGGG |
AGGGTTGCTT |
TCCACCCTCA |
TTGCTTCTTA |
AACAGCTGTT |
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721 |
GTGAACGGAT |
ACCTCTCTAT |
ATGCTGGTGC |
CTTGGTGATG |
CTTACAACCT |
AATTAAATCT |
CATTTGACCA |
AAATGCCTTG |
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801 |
GGGTGGACGT |
AAGATGCCTG |
ATGCCTTTCA |
TGTTCAACAG |
AATACATCAG |
CAGACCCTGT |
TGTTGTGAAC |
TCCCAGGAAC |
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881 |
GTCCAAGTGC |
TTTTTTTGAG |
ATTTTTTAAA |
AAACAGTTTA |
ATTGAAATAT |
AACCTACACA |
GCACAAAAAT |
TACCCTTTGA |
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961 |
AAGTGTGCAC |
TTCACACTTT |
CGGAGGCTGA |
GGCGGGCGGA |
TCACCTGAGG |
TCAGGAGTTC |
AAGACCTGCC |
TGGCCAACTT |
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1041 |
GGCGAAACCC |
CGTCTCTACT |
AAAAATACAA |
AAATTAGCCG |
GGCATGGTAG |
CGCACGCCCG |
TAATCCCAGC |
TACTCGGGAG |
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1121 |
GCTAAGGCAG |
GAGAATCGCT |
TGAACCTGGG |
AGGCGGAGGT |
TGCAGTGAGC |
CGAGATTGTG |
CCAATGCACT |
CCAGCCTCGG |
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1201 |
CGACAGAGCG |
AGACTCCGTC |
ATAAAAATAA |
AAAATTGAAA |
AAAAAAAAAG |
AAAGAAAGCA |
TATACTTCAG |
TGTTGTTCTG |
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1281 |
GATTTTTTTC |
TTCAAGATGC |
CTAGTTAATG |
ACAATGAAAT |
TCTGTACTCG |
GATGGTATCT |
GTCTTTCCAC |
ACTGTAATGC |
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1361 |
CATATTCTTT |
TCTCACCTTT |
TTTTCTGTCG |
GATTCAGTTG |
CTTCCACAGC |
TTTAATTTTT |
TTCCCCTGGA |
GAATCACCCC |
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1441 |
AGTTGTTTTT |
CTTTTTGGCC |
AGAAGAGAGT |
AGCTGTTTTT |
TTTCTTAGTA |
TGTTTGCTAT |
GGTGGTTATA |
CTGCATCCCC |
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1521 |
GTAATCACTG |
GGAAAAGATC |
AGTGGTATTC |
TTCTTGAAAA |
TGAATAAGTG |
TTATGATATT |
TTCAGATTAG |
AGTTACAACT |
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1601 |
GGCTGTCTTT |
TTGGACTTTG |
TGTGGCCATG |
TTTTCATTGT |
AATGCAGTTC |
TGGTAACGGT |
GATAGTCAGT |
TATACAGGGA |
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1681 |
GACTCCCCTA |
GCAGAAAATG |
AGAGTGTGAG |
CTAGGGGGTC |
CCTTGGGGAA |
CCCGGGGCAA |
TAATGCCCTT |
CTCTGCCCTT |
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1761 |
AATCCTTACA |
GTGGGCCGGG |
CACGGTGGCT |
TACGCCTGTA |
ATACCAGCAC |
TTTGGGAGGC |
CGAGGCGGGC |
GGATCACGAG |
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1841 |
GTCAGGAGAT |
CGAGACCATC |
TTGGCTAATA |
CGGTGAAACC |
CCGTCTCCAC |
TAAAAATACA |
AAAAATTAGC |
CGGGCGTGGT |
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1921 |
GGTGGGCGCC |
TGTAGTCCCA |
GCTACTCGGG |
AGGCTGAGGC |
AGGAGAATGG |
CGTGAACCCA |
GGAGGCGGAG |
CTTGCAGTGA |
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2001 |
GCCGAGATTG |
CACCACTGCA |
CTCCAGCCTG |
GGCGACAGAA |
TGAGACTCCG |
TCTCAAAAAA |
AAAAAAAAAA |
GAAAAAAATC |
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2081 |
TTTACAGTGG |
ATTACATAAC |
AATTCCAGTG |
AAATGAAATT |
ACTTCAAACA |
GTTCCTTGAG |
AATGTTGGAG |
GGATTTGACA |
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2161 |
TGTAATTCCT |
TTGGACATAT |
ACCATGTAAC |
ACTTTTCCAA |
CTAATTGCTA |
AGGAAGTCCA |
GATAAAATAG |
ATACATTAGC |
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2241 |
CACACAGATG |
TGGGGGGAGA |
TGTCCACAGG |
GAGAGAGAAG |
GTGCTAAGAG |
GTGCCATATG |
GGAATGTGGC |
TTGGGCAAAG |
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2321 |
CACTGATGCC |
ATCAACTTCA |
GACTTGACGT |
CTTACTCCTG |
AGGCAGAGCA |
GGGTGTGCCT |
GTGGAGGGCG |
TGGGGAGGTG |
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2401 |
GCCCGTGGGG |
AGTGGACTGC |
CGCTTTAATC |
CCTTCAGCTG |
CCTTTCCGCT |
GTTGTTTTGA |
TTTTTCTAGA |
GAGGAACATA |
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2481 |
AAAAGCATTC |
GTCCGGTTGC |
GCTTTCCTTT |
CTGTCAAGAA |
GCAGTTTGAA |
GAATTAACCC |
TTGGTGAATT |
TTTGAAACTG |
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2561 |
GACAGAGAAA |
GAGCCAAGAA |
CAAAATTGTA |
TGTATTGGGA |
ATAAGAACTG |
CTCAAACCCT |
GTTCAATGTC |
TTTAGCACTA |
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2641 |
AACTACCTAG |
TCCCTCAAAG |
GGACTCTGTG |
TTTTCCTCAG |
GAAGCATTTT |
TTTTTTTTTT |
CTGAGATAGA |
GTTTCACTCT |
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2721 |
TGTTGCCCAG |
GCTGGAGTGC |
AATGGTGCAA |
TCTTGGCTCA |
CTGCAACCTC |
TGCCTCTCGG |
GTTCAAGTGA |
TTCTCCTGCC |
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2801 |
TCAGCCTCCC |
AAGTAACTGG |
GATTACAGGG |
AAGTGCCACC |
ACACCCAGCT |
AATTTTTGTA |
TTTTTAGTAG |
AGATGGGGTT |
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2881 |
TCACCACATT |
GCCCAGGCTG |
GTCTTGAACT |
CCTGACCTCG |
TGATTCGCCC |
ACCTTGGCCT |
CCCAAAGTGC |
TGGGATTACA |
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2961 |
GGCGTGAACC |
ACCACGCCTG |
GCTTTTTTTT |
TTTTGTTCTG |
AGACACAGTT |
TCACTCTGTT |
ACCCAGGCTG |
GAGTGGGGTG |
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3041 |
GCCTGATCTC |
GGATCACTGC |
AACCTCCGCC |
TCCTGGGCTC |
AAGTGATTTG |
CCTGCTTCAG |
CCTCCCAAGT |
AGCCGAGATT |
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3121 |
ACAGGCATGT |
GCCACCACAC |
CCAGGTAATT |
TTTGTATTTT |
TGGTAGAGAC |
GAGGTTTCAC |
CATGTTGGCC |
AGGCTGGTCT |
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3201 |
TGAACTCCTG |
ACCTCAGGTG |
ATCCACCCGC |
CTCAGCCTCC |
CAAAGTGCTG |
AGATTATAGG |
TGTGAGCCAC |
CACACCTGGC |
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3281 |
CTCAGGAAGT |
ATTTTTATTT |
TTAAATTTAT |
TTATTTATTT |
GAGATGGAGT |
CTTGCTCTGT |
CGCCCAGGCT |
AGAGTGCAGC |
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3361 |
GACGGGATCT |
CGGCTCACTG |
CAAGCTCCGC |
CCCCCAGGTT |
CAAGCCATTC |
TCCTGCCTCA |
GCCTCCCGAG |
TAGCTGGGAC |
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3441 |
TACAGGCGCC |
CGCCACCACA |
CCCGGCTAAT |
TTTTTTGTAT |
TTTTAGTAGA |
GACGGGTTTT |
CACCGTGTTA |
GCCAGGAGGG |
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3521 |
TCTCGATCTC |
CTGACCTCGT |
GATCTGCCTG |
CCTCGGCCTC |
CCAAAGTGCT |
GGGATTACAG |
GTGTGAGCCA |
CCACACCCGG |
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3601 |
CTATTTTTAT |
TTTTTTGAGA |
CAGGGACTCA |
CTCTGTCACC |
TGGGCTGCAG |
TGCAGTGGTA |
CACCATAGCT |
CACTGCAGCC |
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3681 |
TCGAACTCCT |
GAGCTCAAGT |
GATCCTCCCA |
CCTCATCCTC |
CCAAGTAATT |
GGGACTACAG |
GCGCACCCCA |
CCATGCCCAC |
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3761 |
CTTATTTATT |
TATTTATTTA |
TTTATTTATT |
TATTTTCATA |
GAGATGAGGG |
TTCCCTGTGT |
TGTCCAGGCT |
GGTCTTGAAC |
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3841 |
TCCTGAGCTC |
AAGGGATCCT |
TTTGCCTGGG |
CCTCCCAAAG |
TGCTGAGATT |
ACAGGCATGA |
GCCACCGTGC |
CCAGCTAGGA |
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3921 |
ATCATTTTTA |
AAGCCCCTAG |
GATGTCTGTG |
TGATTTTAAA |
GCTCCTGGAG |
TGTGGCCGGT |
ATAAGTATAT |
ACCGGTATAA |
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4001 |
GTAAATCCCA |
CATTTTGTGT |
CAGTATTTAC |
TAGAAACTTA |
GTCATTTATC |
TGAAGTTGAA |
ATGTAACTGG |
GCTTTATTTA |
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4081 |
TTTATTTATT |
TATTTATTTA |
TTTTTAATTT |
TTTTTTTTGA |
GACGAGTCTC |
ACTTTGTCAC |
CCAGGCTGGA |
GTGCAGTGGC |
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4161 |
ACGATCTCGG |
CTCACTGCAA |
CCTCTGCCTC |
CCGGGGTCAA |
GCGATTCTCC |
TGCCTTAGCC |
TCCCGAGTAG |
CTGGGACTAC |
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4241 |
AGGCACGCAC |
CACCATGCCT |
GGCTAATTTT |
TGTATTTTTA |
GTAGACGGGG |
TTTCACCATG |
CTGGCCAAGC |
TGGTCTCAAA |
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4321 |
CTCCTGACCT |
TGTGATCTGC |
CCGCTTTAGC |
CTCCCAGAGT |
GCTGGGATTA |
CAGGCATGAG |
CCACCATGCG |
TGGTCTTTTT |
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4401 |
AAAATTTTTT |
GATTTTTTTT |
TTTTTTGAGA |
CAGAGCCTTG |
CTCTGTCGCC |
CAGGCTGGAG |
TGCAGTGGCA |
CGATCTCAGC |
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4481 |
TCACTACAAG |
CTCCGCCTCC |
CGGGTTCACG |
CCATTCTTCT |
GCCTCAGCCT |
CCTGAGTAGC |
TGGGACTACA |
GGTGCCCACC |
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4561 |
ACCACGCCTG |
GCTAATTTTT |
TTTGGTATTT |
TTATTAGAGA |
CAAGGTTTCA |
TCATGTTGGC |
CAGGCTGGTC |
TCAAACTCCT |
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4641 |
GACCTCAAGT |
GATCTGCCTG |
CCTCGGCCTC |
CCAAAGCGCT |
GAGATTACAG |
GTGTGATCTA |
CTGCACCAGG |
CCTGGGCGTC |
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4721 |
ATATATTCTT |
ATTTGCTAAG |
TCTGGCAGCC |
CCACACAGAA |
TAAGTACTGG |
GGGATTCCAT |
ATCCTTGTAG |
CAAAGCCCTG |
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4801 |
GGTGGAGAGT |
CAGGAGATGT |
TGTAGTTCTG |
TCTCTGCCAC |
TTGCAGACTT |
TGAGTTTAAG |
CCAGTCGTGC |
TCATGCTTTC |
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4881 |
CTTGCTAAAT |
AGAGGTTAGA |
CCCCCTATCC |
CATGGTTTCT |
CAGGTTGCTT |
TTCAGCTTGA |
AAATTGTATT |
CCTTTGTAGA |
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4961 |
GATCAGCGTA |
AAATAATTCT |
GTCCTTATAT |
GTGGCTTTAT |
TTTAATTTGA |
GACAGAGTGT |
CACTCAGTCG |
CCCAGGCTGG |
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5041 |
AGTGTGGTGG |
TGCGATCTTG |
GCTCACTGCG |
ACCTCCACCT |
CCCAGGTTCA |
AGCGATTCTC |
GTGCCTCAGG |
CTCCCAAGTA |
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5121 |
GCTGAGATTA |
TAGGTGTGTG |
CCACCAGGCC |
CAGCTAACTT |
TTGTATTTTT |
AGTAGAGACA |
GGGTTTTGCC |
ATGTTGGCTA |
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5201 |
AGCTGGTCTC |
GAACTCCTGG |
CCTCAAGTGA |
TCTGCCCGCC |
TTGGCATCCC |
AAAGTGCTGG |
GATTACAGGT |
GTGAACCACC |
|
5281 |
ACACCTGGCC |
TCAATATAGT |
GGCTTTTAAG |
TGCTAAGGAC |
TGAGATTGTG |
TTTTGTCAGG |
AAGAGGCCAG |
TTGTGGGTGA |
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5361 |
AGCATGCTGT |
GAGAGAGCTT |
GTCACCTGGT |
TGAGGTTGTG |
GGAGCTGCAG |
CGTGGGAACT |
GGAAAGTGGG |
CTGGGGATCA |
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5441 |
TCTTTTTCCA |
GGTCAGGGGT |
CAGCCAGCTT |
TTCTGCAGCG |
TGCCATAGAC |
CATCTCTTAG |
CCCTCGTGGG |
TCAGAGTCTC |
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5521 |
TGTTGCATAT |
TGTCTTTTGT |
TGTTTTTCAC |
AACCTTTTAG |
AAACATAAAA |
AGCATTCTTA |
GCCCGTGGGC |
TGGACAAAAA |
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5601 |
AAGGCCATGA |
CGGGCTGTAT |
GGATTTGGCC |
CAGCAGGCCC |
TTGCTTGCCA |
AGCCCTGTTT |
TAGACAAGGA |
GCAGCTTGTG |
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5681 |
TGCCTGGAAC |
CATCATGGGC |
ACAGGGGAGG |
AGCAGAGTGG |
ATGTGGAGGT |
GTGAGCTGGA |
AACCAGGTCC |
CAGAGCGCTG |
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5761 |
AGAAAGACAG |
AGGGTTTTTG |
CCCTTGCAAA |
TAGAGCAACT |
GAAATCTGAC |
ACCATCCAGT |
TCCAGAAAGC |
CCTGAAGTGC |
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5841 |
TGGTGGACGC |
TGCGGGGTGC |
TCCGCTCTAG |
GGTTACAGGG |
ATGAAGATGC |
AGTCTGGTAG |
GGGGAGTCCA |
CTCACCTGTT |
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5921 |
GGAAGATGTG |
ATTAAGAAAA |
GTAGACTTTC |
AGGGCCGGGC |
ATGGTGGCTC |
ACGCCTGTAA |
TCCCAGCACT |
TTGGGAGGCC |
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6001 |
GAGGCGGGTG |
GATCACGAGG |
TCAGGAGATC |
GAGACCATCC |
TGGCTAACAT |
GGTGAAACCC |
CGTCTTTACT |
AAAAATACAA |
|
6081 |
AAAATTAGCT |
GGGCGTGGTG |
GCGGGCGCCT |
GTAGTCCCAG |
CTACTCGGGA |
GGCTGAGGCA |
GGAGAATGGC |
GTGAACCTGG |
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6161 |
GAGGTGGAGC |
TTGCAGTGAG |
CCGAGATCGC |
GCCACTGCAC |
TCCAGCCTGG |
GCGACAGAGC |
GAGACTCCGT |
CTCAAAAAAA |
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6241 |
AAAAAAAAAA |
GTAGGCTTTC |
ATGATGTGTG |
AGCTGAAGGC |
GCAGTAGGCA |
GAAGTAGAGG |
CCTCAGTCCC |
TGCAGGAGAC |
|
6321 |
CTCTCGGTCT |
CTATCTCCTG |
ATAGTCAGAC |
CCAGCCACAC |
TGGAAAGAGG |
GGAGACATTA |
CAGCCTGCAA |
GAAAAGTAGG |
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6401 |
GAGATTTAAA |
AACTGCTTGG |
CTTTTATTTT |
GAACTGTTTT |
TTTTGTTTGT |
TTGTTTTCCC |
CAATTCAGAA |
TACAGAATAC |
|
6481 |
TTTTATGGAT |
TTGTTTTTAT |
TACTTTAATT |
TTGAAACAAT |
ATAATCTTTT |
TTTTGTTGTT |
TTTTTGAGAC |
GGGGTCTTAC |
|
6561 |
TCTGTCACCC |
AGGCTGAGTG |
CAGTGGTGTG |
ATCTTGGCTC |
ACCTCAGCCT |
CGACCCCCTG |
GGCTCAAATG |
ATTCTCCCAC |
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6641 |
CTCAGCTTCC |
CAAGTAGCTG |
GGACCACAGG |
TGCGTGTGTT |
GCGCTATACA |
AATCCTGAAG |
ACAAGGATGC |
TGTTGCTGGT |
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6721 |
GATGCTGGGG |
ATTCCCAAGA |
TCCCAGATTT |
GATGGCAGGA |
TGCCCCTGTC |
TGCTGCCTTG |
CCAGGGTGCC |
AGGAGGGCGC |
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6801 |
TGCTGTGGAA |
GCTGAGGCCC |
GGCCATCCAG |
GGCGATGCAT |
TGGGCGCTGA |
TTCTTGTTCC |
TGCTGCTGCC |
TCGGTGCTTA |
|
6881 |
GCTTTTGAAA |
CAATGAAATA |
AATTAGAACC |
AGTGTGAAAA |
TCGATCAGGA |
AATAAATTTA |
ATGTGGAAAT |
AAACTGAACA |
|
6961 |
ACTTAGTTCT |
TCATAAGAGT |
TTACTTGGTA |
AATACTTGTG |
ATGAGGACAA |
AACGAAGCAC |
TAGAAGGAGA |
GGCGAGTTGT |
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7041 |
AGACCTGGGT |
GGCAGGAGTG |
TTTTGTTTGT |
TTTCTTTGGC |
AGGGTCTTGC |
TCTGTTGCTC |
AGGCTGGAGT |
ACAGTGGCGC |
|
7121 |
AATCACAGCT |
CACTATAGCC |
TCGACCTCCT |
GGACTCAAGC |
AATCCTCCTG |
CCTCAGCCTC |
CCAGTAGCTG |
GGACTACAGG |
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7201 |
CGCATGCCAC |
CATGCCTGGC |
TAATTTTAAA |
TTTTTTTTTT |
TCTCTTTTTT |
GAGATGGAAT |
CTCACTCTGT |
CGCCCAGGCT |
|
7281 |
GGAGTGCAGT |
GGCGTGATCT |
CGGCTGACGG |
CAAGCTCCGC |
CTCCCAGGTT |
CACTCCATTC |
GCCTGCCTCA |
GCCTCCCAAG |
|
7361 |
TAGCTGGGAC |
TACAGGCGCT |
GGGATTACAA |
ACCCAAACCC |
AAAGTGCTGG |
GATTACAGGC |
GTGAGCCACC |
GCACCCGGCC |
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7441 |
TGTTTTGTCT |
TTCAATAGCA |
AGAGTTGTGT |
TTGCTTCGCC |
CCTACCTTTA |
GTGGAAAAAT |
GTATAAAATG |
GAGATATTGA |
|
7521 |
CCTCCACATT |
GGGGTGGTTA |
AATTATAGCA |
TGTATGCAAA |
GGAGCTTCGC |
TAATTTAAGG |
CTTTTTTGAA |
AGAGAAGAAA |
|
7601 |
CTGAATAATC |
CATGTGTGTA |
TATATATTTT |
AAAAGCCATG |
GTCATCTTTC |
CATATCAGTA |
AAGCTGAGGC |
TCCCTGGGAC |
|
7681 |
TGCAGAGTTG |
TCCATCACAG |
TCCATTATAA |
GTGCGCTGCT |
GGGCCAGGTG |
CAGTGGCTTG |
TGCCTGAATC |
CCAGCACTTT |
|
7761 |
GGGAGGCCAA |
GGCAGGAGGA |
TTCATTGAGC |
CCAGGAGTTT |
TGAGGCGAGC |
CTGGGCAATG |
TGGCCAGACC |
TCATCTCTTC |
|
7841 |
AAAAAATACA |
CAAAAAATTA |
GCCAGGCATG |
GTGGCACGTG |
CCTGTAGTCT |
CAGCTACTCA |
GGAGGCTGAG |
GTGGGAGGAT |
|
7921 |
CACTTTGAGC |
CTTGCAGGTC |
AAAGCTGCAG |
TAAGCCATGA |
TCTTGCCACT |
GCATTCCAGC |
CTGGATGACA |
GAGCGAGACC |
|
8001 |
CTGTCTCTAA |
AAAAAAAAAA |
ACCAAACGGT |
GCACTGTTTT |
CTTTTTTCTT |
ATCAATTTAT |
TATTTTTAAA |
TTAAATTTTC |
|
8081 |
TTTTAATAAT |
TTATAAATTA |
TAAATTTATA |
TTAAAAAATG |
ACAAATTTTT |
ATTACTTATA |
CATGAGGTAA |
AACTTAGGAT |
|
8161 |
ATATAAAGTA |
CATATTGAAA |
AGTAATTTTT |
TGGCTGGCAC |
AGTGGCTCAC |
ACCTGTAATC |
CCAGCACTTT |
GGGAGGCCGT |
|
8241 |
GGCGGGCAGA |
TCACATGAGA |
TCATGAGTTC |
GAGACCAACC |
TGACCAACAT |
GGAGAGACCC |
CATCTCTACT |
AAAAATACAA |
|
8321 |
AATTAGCCGG |
GGTGGTGGCG |
CATGCCTGTA |
ATCCCAGCTA |
CTCGGGAGGC |
TGAGGCAGGA |
GAATCTCTTG |
AACCCGGGAG |
|
8401 |
GCAGAGGTTG |
CGGTGAGCCA |
AGATCGTGCC |
TTTGCACACC |
AGCCAAGGCA |
ACAAGAGCGA |
AAGTCCGTCT |
CAAAAAAAAA |
|
8481 |
GTAATTTTTT |
TTAAGTTAAC |
CTCTGTCAGC |
AAACAAATTT |
AACCCAATAA |
AGGTCTTTGT |
TTTTTAATGT |
AGTAGAGGAG |
|
8561 |
TTAGGGTTTA |
TAAAAAATAT |
GGTAGGGAAG |
GGGGTCCCTG |
GATTTGCTAA |
TGTGATTGTC |
ATTTGCCCCT |
TAGGAGAGAG |
|
8641 |
CTCTGTTAGC |
AGAATGAAAA |
AATTGGAAGC |
CAGATTCAGG |
GAGGGACTGG |
AAGCAAAAGA |
ATTTCTGTTC |
GAGGAAGAGC |
|
8721 |
CTGATGTTTG |
CCAGGGTCTG |
TTTAACTGGA |
CATGAAGAGG |
AAGGCTCTGG |
ACTTTCCTCC |
AGGAGTTTCA |
GGAGAAAGGT |
|
8801 |
AGGGCAGTGG |
TTAAGAGCAG |
AGCTCTGCCT |
AGACTAGCTG |
GGGTGCCTAG |
ACTAGCTGGG |
GTGCCCAGAC |
TAGCTGGGGT |
|
8881 |
GCCTAGACTA |
GCTGGGTACT |
TTGAGTGGCT |
CCTTCAGCCT |
GGACCTCGGT |
TTCCTCACCT |
GTATAGTAGA |
GATATGGGAG |
|
8961 |
CACCCAGCGC |
AGGATCACTG |
TGAACATAAA |
TCAGTTAATG |
GAGGAAGCAG |
GTAGAGTGGT |
GCTGGGTGCA |
TACCAAGCAC |
|
9041 |
TCCGTCAGTG |
TTTCCTGTTA |
TTCGATGATT |
AGGAGGCAGC |
TTAAACTAGA |
GGGAGTTGAG |
CTGAATCAGG |
ATGTTTGTCC |
|
9121 |
CAGGTAGCTG |
GGAATCTGCC |
TAGCCCAGTG |
CCCAGTTTAT |
TTAGGTGCTC |
TCTCAGTGTT |
CCCTGATTGT |
TTTTTCCTTT |
|
9201 |
GTCATCTTAT |
CTACAGGATG |
TGACTGGGAA |
GCTCTGGTTT |
CAGTGTCATG |
TGTCTATTCT |
TTATTTCCAG |
GCAAAGGAAA |
|
9281 |
CCAACAATAA |
GAAGAAAGAA |
TTTGAGGAAA |
CTGCGGAGAA |
AGTGCGCCGT |
GCCATCGAGC |
AGCTGGCTGC |
CATGGATTGA |
|
9361 |
GGCCTCTGGC |
CGGAGCTGCC |
TGGTCCCAGA |
GTGGCTGCAC |
CACTTCCAGG |
GTTTATTCCC |
TGGTGCCACC |
AGCCTTCCTG |
|
9441 |
TGGGCCCCTT |
AGCAATGTCT |
TAGGAAAGGA |
GATCAACATT |
TTCAAATTAG |
ATGTTTCAAC |
TGTGCTCTTG |
TTTTGTCTTG |
|
9521 |
AAAGTGGCAC |
CAGAGGTGCT |
TCTGCCTGTG |
CAGCGGGTGC |
TGCTGGTAAC |
AGTGGCTGCT |
TCTCTCTCTC |
TCTCTCTTTT |
|
9601 |
TTGGGGGCTC |
ATTTTTGCTG |
TTTTGATTCC |
CGGGCTTACC |
AGGTGAGAAG |
TGAGGGAGGA |
AGAAGGCAGT |
GTCCCTTTTG |
|
9681 |
CTAGAGCTGA |
CAGCTTTGTT |
CGCGTGGGCA |
GAGCCTTCCA |
CAGTGAATGT |
GTCTGGACCT |
CATGTTGTTG |
AGGCTGTCAC |
|
9761 |
AGTCCTGAGT |
GTGGACTTGG |
CAGGTGCCTG |
TTGAATCTGA |
GCTGCAGGTT |
CCTTATCTGT |
CACACCTGTG |
CCTCCTCAGA |
|
9841 |
GGACAGTTTT |
TTTGTTGTTG |
TGTTTTTTTG |
TTTTTTTTTT |
TTTGGTAGAT |
GCATGACTTG |
TGTGTGATGA |
GAGAATGGAG |
|
9921 |
ACAGAGTCCC |
TGGCTCCTCT |
ACTGTTTAAC |
AACATGGCTT |
TCTTATTTTG |
TTTGAATTGT |
TAATTCACAG |
AATAGCACAA |
|
10001 |
ACTACAATTA |
AAACTAAGCA |
CAAAGCCATT |
CTAAGTCATT |
GGGGAAACGG |
GGTGAACTTC |
AGGTGGATGA |
GGAGACAGAA |
|
10081 |
TAGAGTGATA |
GGAAGCGTCT |
GGCAGATACT |
CCTTTTGCCA |
CTGCTGTGTG |
ATTAGACAGG |
CCCAGTGAGC |
CGCGGGGCAC |
|
10161 |
ATGCTGGCCG |
CTCCTCCCTC |
AGAAAAAGGC |
AGTGGCCTAA |
ATCCTTTTTA |
AATGACTTGG |
CTCGATGCTG |
TGGGGGACTG |
|
10241 |
GCTGGGCTGC |
TGCAGGCCGT |
GTGTCTGTCA |
GCCCAACCTT |
CACATCTGTC |
ACGTTCTCCA |
CACGGGGGAG |
AGACGCAGTC |
|
10321 |
CGCCCAGGTC |
CCCGCTTTCT |
TTGGAGGCAG |
CAGCTCCCGC |
AGGGCTGAAG |
TCTGGCGTAA |
GATGATGGAT |
TTGATTCGCC |
|
10401 |
CTCCTCCCTG |
TCATAGAGCT |
GCAGGGTGGA |
TTGTTACAGC |
TTCGCTGGAA |
ACCTCTGGAG |
GTCATCTCGG |
CTGTTCCTGA |
|
10481 |
GAAATAAAAA |
GCCTGTCATT |
TCAAACACTG |
CTGTGGACCC |
TACTGGGTTT |
TTAAAATATT |
GTCAGTTTTT |
CATCGTCGTC |
|
10561 |
CCTAGCCTGC |
CAACAGCCAT |
CTGCCCAGAC |
AGCCGCAGTG |
AGGATGAGCG |
TCCTGGCAGA |
GACGCAGTTG |
TCTCTGGGCG |
|
10641 |
CTTGCCAGAG |
CCACGAACCC |
CAGACCTGTT |
TGTATCATCC |
GGGCTCCTTC |
CGGGCAGAAA |
CAACTGAAAA |
TGCACTTCAG |
|
10721 |
ACCCACTTAT |
TTCTGCCACA |
TCTGAGTCGG |
CCTGAGATAG |
ACTTTTCCCT |
CTAAACTGGG |
AGAATATCAC |
AGTGGTTTTT |
|
10801 |
GTTAGCAGAA |
AATGCACTCC |
AGCCTCTGTA |
CTCATCTAAG |
CTGCTTATTT |
TTGATATTTG |
TGTCAGTCTG |
TAAATGGATA |
|
10881 |
CTTCACTTTA |
ATAACTGTTG |
CTTAGTAATT |
GGCTTTGTAG |
AGAAGCTGGA |
AAAAAATGGT |
TTTGTCTTCA |
ACTCCTTTGC |
|
10961 |
ATGCCAGGCG |
GTGATGTGGA |
TCTCGGCTTC |
TGTGAGCCTG |
TGCTGTGGGC |
AGGGCTGAGC |
TGGAGCCGCC |
CCTCTCAGCC |
|
11041 |
CGCCTGCCAC |
GGCCTTTCCT |
TAAAGGCCAT |
CCTTAAAACC |
AGACCCTCAT |
GGCTACCAGC |
ACCTGAAAGC |
TTCCTCGACA |
|
11121 |
TCTGTTAATA |
AAGCCGTAGG |
CCCTTGTCTA |
AGTGCAACCG |
CCTAGACTTT |
CTTTCAGATA |
CATGTCCACA |
TGTCCATTTT |
|
11201 |
TCAGGTTCTC |
TAAGTTGGAG |
TGGAGTCTGG |
GAAGGGTTGT |
GAATGAGGCT |
TCTGGGCTAT |
GGGTGAGGTT |
CCAATGGCAG |
|
11281 |
GTTAGAGCCC |
CTCGGGCCAA |
CTGCCATCCT |
GGAAAGTAGA |
GACAGCAGTG |
CCCGCTGCCC |
AGAAGAGACC |
AGCAAGCCAA |
|
11361 |
ACTGGAGCCC |
CCATTGCAGG |
CTGTCGCCAT |
GTGGAAAGAG |
TAACTCACAA |
TTGCCAATAA |
AGTCTCATGT |
GGTTTTATCT |
|
|
|
|
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>ref|Gene_ID:332|BIRC5|NC_000017.10:76210276...76221715 (+)
TCCCAGAAGGCCGCGGGGGGTGGACCGCCTAAGAGGGCGTGCGCTCCCGACATGCCCCGCGGCGCGCCATTAACCGCCAG
ATTTGAATCGCGGGACCCGTTGGCAGAGGTGGCGGCGGCGGCATGGGTGCCCCGACGTTGCCCCCTGCCTGGCAGCCCTT
TCTCAAGGACCACCGCATCTCTACATTCAAGAACTGGCCCTTCTTGGAGGGCTGCGCCTGCACCCCGGAGCGGGTGAGAC
TGCCCGGCCTCCTGGGGTCCCCCACGCCCGCCTTGCCCTGTCCCTAGCGAGGCCACTGTGACTGGGCCTCGGGGGTACAA
GCCGCCCTCCCCTCCCCGTCCTGTCCCCAGCGAGGCCACTGTGGCTGGGCCCCTTGGGTCCAGGCCGGCCTCCCCTCCCT
GCTTTGTCCCCATCGAGGCCTTTGTGGCTGGGCCTCGGGGTTCCGGGCTGCCACGTCCACTCACGAGCTGTGCTGTCCCT
TGCAGATGGCCGAGGCTGGCTTCATCCACTGCCCCACTGAGAACGAGCCAGACTTGGCCCAGTGTTTCTTCTGCTTCAAG
GAGCTGGAAGGCTGGGAGCCAGATGACGACCCCATGTAAGTCTTCTCTGGCCAGCCTCGATGGGCTTTGTTTTGAACTGA
GTTGTCAAAAGATTTGAGTTGCAAAGACACTTAGTATGGGAGGGTTGCTTTCCACCCTCATTGCTTCTTAAACAGCTGTT
GTGAACGGATACCTCTCTATATGCTGGTGCCTTGGTGATGCTTACAACCTAATTAAATCTCATTTGACCAAAATGCCTTG
GGGTGGACGTAAGATGCCTGATGCCTTTCATGTTCAACAGAATACATCAGCAGACCCTGTTGTTGTGAACTCCCAGGAAC
GTCCAAGTGCTTTTTTTGAGATTTTTTAAAAAACAGTTTAATTGAAATATAACCTACACAGCACAAAAATTACCCTTTGA
AAGTGTGCACTTCACACTTTCGGAGGCTGAGGCGGGCGGATCACCTGAGGTCAGGAGTTCAAGACCTGCCTGGCCAACTT
GGCGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCCGGGCATGGTAGCGCACGCCCGTAATCCCAGCTACTCGGGAG
GCTAAGGCAGGAGAATCGCTTGAACCTGGGAGGCGGAGGTTGCAGTGAGCCGAGATTGTGCCAATGCACTCCAGCCTCGG
CGACAGAGCGAGACTCCGTCATAAAAATAAAAAATTGAAAAAAAAAAAAGAAAGAAAGCATATACTTCAGTGTTGTTCTG
GATTTTTTTCTTCAAGATGCCTAGTTAATGACAATGAAATTCTGTACTCGGATGGTATCTGTCTTTCCACACTGTAATGC
CATATTCTTTTCTCACCTTTTTTTCTGTCGGATTCAGTTGCTTCCACAGCTTTAATTTTTTTCCCCTGGAGAATCACCCC
AGTTGTTTTTCTTTTTGGCCAGAAGAGAGTAGCTGTTTTTTTTCTTAGTATGTTTGCTATGGTGGTTATACTGCATCCCC
GTAATCACTGGGAAAAGATCAGTGGTATTCTTCTTGAAAATGAATAAGTGTTATGATATTTTCAGATTAGAGTTACAACT
GGCTGTCTTTTTGGACTTTGTGTGGCCATGTTTTCATTGTAATGCAGTTCTGGTAACGGTGATAGTCAGTTATACAGGGA
GACTCCCCTAGCAGAAAATGAGAGTGTGAGCTAGGGGGTCCCTTGGGGAACCCGGGGCAATAATGCCCTTCTCTGCCCTT
AATCCTTACAGTGGGCCGGGCACGGTGGCTTACGCCTGTAATACCAGCACTTTGGGAGGCCGAGGCGGGCGGATCACGAG
GTCAGGAGATCGAGACCATCTTGGCTAATACGGTGAAACCCCGTCTCCACTAAAAATACAAAAAATTAGCCGGGCGTGGT
GGTGGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACCCAGGAGGCGGAGCTTGCAGTGA
GCCGAGATTGCACCACTGCACTCCAGCCTGGGCGACAGAATGAGACTCCGTCTCAAAAAAAAAAAAAAAAGAAAAAAATC
TTTACAGTGGATTACATAACAATTCCAGTGAAATGAAATTACTTCAAACAGTTCCTTGAGAATGTTGGAGGGATTTGACA
TGTAATTCCTTTGGACATATACCATGTAACACTTTTCCAACTAATTGCTAAGGAAGTCCAGATAAAATAGATACATTAGC
CACACAGATGTGGGGGGAGATGTCCACAGGGAGAGAGAAGGTGCTAAGAGGTGCCATATGGGAATGTGGCTTGGGCAAAG
CACTGATGCCATCAACTTCAGACTTGACGTCTTACTCCTGAGGCAGAGCAGGGTGTGCCTGTGGAGGGCGTGGGGAGGTG
GCCCGTGGGGAGTGGACTGCCGCTTTAATCCCTTCAGCTGCCTTTCCGCTGTTGTTTTGATTTTTCTAGAGAGGAACATA
AAAAGCATTCGTCCGGTTGCGCTTTCCTTTCTGTCAAGAAGCAGTTTGAAGAATTAACCCTTGGTGAATTTTTGAAACTG
GACAGAGAAAGAGCCAAGAACAAAATTGTATGTATTGGGAATAAGAACTGCTCAAACCCTGTTCAATGTCTTTAGCACTA
AACTACCTAGTCCCTCAAAGGGACTCTGTGTTTTCCTCAGGAAGCATTTTTTTTTTTTTTCTGAGATAGAGTTTCACTCT
TGTTGCCCAGGCTGGAGTGCAATGGTGCAATCTTGGCTCACTGCAACCTCTGCCTCTCGGGTTCAAGTGATTCTCCTGCC
TCAGCCTCCCAAGTAACTGGGATTACAGGGAAGTGCCACCACACCCAGCTAATTTTTGTATTTTTAGTAGAGATGGGGTT
TCACCACATTGCCCAGGCTGGTCTTGAACTCCTGACCTCGTGATTCGCCCACCTTGGCCTCCCAAAGTGCTGGGATTACA
GGCGTGAACCACCACGCCTGGCTTTTTTTTTTTTGTTCTGAGACACAGTTTCACTCTGTTACCCAGGCTGGAGTGGGGTG
GCCTGATCTCGGATCACTGCAACCTCCGCCTCCTGGGCTCAAGTGATTTGCCTGCTTCAGCCTCCCAAGTAGCCGAGATT
ACAGGCATGTGCCACCACACCCAGGTAATTTTTGTATTTTTGGTAGAGACGAGGTTTCACCATGTTGGCCAGGCTGGTCT
TGAACTCCTGACCTCAGGTGATCCACCCGCCTCAGCCTCCCAAAGTGCTGAGATTATAGGTGTGAGCCACCACACCTGGC
CTCAGGAAGTATTTTTATTTTTAAATTTATTTATTTATTTGAGATGGAGTCTTGCTCTGTCGCCCAGGCTAGAGTGCAGC
GACGGGATCTCGGCTCACTGCAAGCTCCGCCCCCCAGGTTCAAGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGAC
TACAGGCGCCCGCCACCACACCCGGCTAATTTTTTTGTATTTTTAGTAGAGACGGGTTTTCACCGTGTTAGCCAGGAGGG
TCTCGATCTCCTGACCTCGTGATCTGCCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCACACCCGG
CTATTTTTATTTTTTTGAGACAGGGACTCACTCTGTCACCTGGGCTGCAGTGCAGTGGTACACCATAGCTCACTGCAGCC
TCGAACTCCTGAGCTCAAGTGATCCTCCCACCTCATCCTCCCAAGTAATTGGGACTACAGGCGCACCCCACCATGCCCAC
CTTATTTATTTATTTATTTATTTATTTATTTATTTTCATAGAGATGAGGGTTCCCTGTGTTGTCCAGGCTGGTCTTGAAC
TCCTGAGCTCAAGGGATCCTTTTGCCTGGGCCTCCCAAAGTGCTGAGATTACAGGCATGAGCCACCGTGCCCAGCTAGGA
ATCATTTTTAAAGCCCCTAGGATGTCTGTGTGATTTTAAAGCTCCTGGAGTGTGGCCGGTATAAGTATATACCGGTATAA
GTAAATCCCACATTTTGTGTCAGTATTTACTAGAAACTTAGTCATTTATCTGAAGTTGAAATGTAACTGGGCTTTATTTA
TTTATTTATTTATTTATTTATTTTTAATTTTTTTTTTTGAGACGAGTCTCACTTTGTCACCCAGGCTGGAGTGCAGTGGC
ACGATCTCGGCTCACTGCAACCTCTGCCTCCCGGGGTCAAGCGATTCTCCTGCCTTAGCCTCCCGAGTAGCTGGGACTAC
AGGCACGCACCACCATGCCTGGCTAATTTTTGTATTTTTAGTAGACGGGGTTTCACCATGCTGGCCAAGCTGGTCTCAAA
CTCCTGACCTTGTGATCTGCCCGCTTTAGCCTCCCAGAGTGCTGGGATTACAGGCATGAGCCACCATGCGTGGTCTTTTT
AAAATTTTTTGATTTTTTTTTTTTTTGAGACAGAGCCTTGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCACGATCTCAGC
TCACTACAAGCTCCGCCTCCCGGGTTCACGCCATTCTTCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGTGCCCACC
ACCACGCCTGGCTAATTTTTTTTGGTATTTTTATTAGAGACAAGGTTTCATCATGTTGGCCAGGCTGGTCTCAAACTCCT
GACCTCAAGTGATCTGCCTGCCTCGGCCTCCCAAAGCGCTGAGATTACAGGTGTGATCTACTGCACCAGGCCTGGGCGTC
ATATATTCTTATTTGCTAAGTCTGGCAGCCCCACACAGAATAAGTACTGGGGGATTCCATATCCTTGTAGCAAAGCCCTG
GGTGGAGAGTCAGGAGATGTTGTAGTTCTGTCTCTGCCACTTGCAGACTTTGAGTTTAAGCCAGTCGTGCTCATGCTTTC
CTTGCTAAATAGAGGTTAGACCCCCTATCCCATGGTTTCTCAGGTTGCTTTTCAGCTTGAAAATTGTATTCCTTTGTAGA
GATCAGCGTAAAATAATTCTGTCCTTATATGTGGCTTTATTTTAATTTGAGACAGAGTGTCACTCAGTCGCCCAGGCTGG
AGTGTGGTGGTGCGATCTTGGCTCACTGCGACCTCCACCTCCCAGGTTCAAGCGATTCTCGTGCCTCAGGCTCCCAAGTA
GCTGAGATTATAGGTGTGTGCCACCAGGCCCAGCTAACTTTTGTATTTTTAGTAGAGACAGGGTTTTGCCATGTTGGCTA
AGCTGGTCTCGAACTCCTGGCCTCAAGTGATCTGCCCGCCTTGGCATCCCAAAGTGCTGGGATTACAGGTGTGAACCACC
ACACCTGGCCTCAATATAGTGGCTTTTAAGTGCTAAGGACTGAGATTGTGTTTTGTCAGGAAGAGGCCAGTTGTGGGTGA
AGCATGCTGTGAGAGAGCTTGTCACCTGGTTGAGGTTGTGGGAGCTGCAGCGTGGGAACTGGAAAGTGGGCTGGGGATCA
TCTTTTTCCAGGTCAGGGGTCAGCCAGCTTTTCTGCAGCGTGCCATAGACCATCTCTTAGCCCTCGTGGGTCAGAGTCTC
TGTTGCATATTGTCTTTTGTTGTTTTTCACAACCTTTTAGAAACATAAAAAGCATTCTTAGCCCGTGGGCTGGACAAAAA
AAGGCCATGACGGGCTGTATGGATTTGGCCCAGCAGGCCCTTGCTTGCCAAGCCCTGTTTTAGACAAGGAGCAGCTTGTG
TGCCTGGAACCATCATGGGCACAGGGGAGGAGCAGAGTGGATGTGGAGGTGTGAGCTGGAAACCAGGTCCCAGAGCGCTG
AGAAAGACAGAGGGTTTTTGCCCTTGCAAATAGAGCAACTGAAATCTGACACCATCCAGTTCCAGAAAGCCCTGAAGTGC
TGGTGGACGCTGCGGGGTGCTCCGCTCTAGGGTTACAGGGATGAAGATGCAGTCTGGTAGGGGGAGTCCACTCACCTGTT
GGAAGATGTGATTAAGAAAAGTAGACTTTCAGGGCCGGGCATGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCC
GAGGCGGGTGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACATGGTGAAACCCCGTCTTTACTAAAAATACAA
AAAATTAGCTGGGCGTGGTGGCGGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACCTGG
GAGGTGGAGCTTGCAGTGAGCCGAGATCGCGCCACTGCACTCCAGCCTGGGCGACAGAGCGAGACTCCGTCTCAAAAAAA
AAAAAAAAAAGTAGGCTTTCATGATGTGTGAGCTGAAGGCGCAGTAGGCAGAAGTAGAGGCCTCAGTCCCTGCAGGAGAC
CTCTCGGTCTCTATCTCCTGATAGTCAGACCCAGCCACACTGGAAAGAGGGGAGACATTACAGCCTGCAAGAAAAGTAGG
GAGATTTAAAAACTGCTTGGCTTTTATTTTGAACTGTTTTTTTTGTTTGTTTGTTTTCCCCAATTCAGAATACAGAATAC
TTTTATGGATTTGTTTTTATTACTTTAATTTTGAAACAATATAATCTTTTTTTTGTTGTTTTTTTGAGACGGGGTCTTAC
TCTGTCACCCAGGCTGAGTGCAGTGGTGTGATCTTGGCTCACCTCAGCCTCGACCCCCTGGGCTCAAATGATTCTCCCAC
CTCAGCTTCCCAAGTAGCTGGGACCACAGGTGCGTGTGTTGCGCTATACAAATCCTGAAGACAAGGATGCTGTTGCTGGT
GATGCTGGGGATTCCCAAGATCCCAGATTTGATGGCAGGATGCCCCTGTCTGCTGCCTTGCCAGGGTGCCAGGAGGGCGC
TGCTGTGGAAGCTGAGGCCCGGCCATCCAGGGCGATGCATTGGGCGCTGATTCTTGTTCCTGCTGCTGCCTCGGTGCTTA
GCTTTTGAAACAATGAAATAAATTAGAACCAGTGTGAAAATCGATCAGGAAATAAATTTAATGTGGAAATAAACTGAACA
ACTTAGTTCTTCATAAGAGTTTACTTGGTAAATACTTGTGATGAGGACAAAACGAAGCACTAGAAGGAGAGGCGAGTTGT
AGACCTGGGTGGCAGGAGTGTTTTGTTTGTTTTCTTTGGCAGGGTCTTGCTCTGTTGCTCAGGCTGGAGTACAGTGGCGC
AATCACAGCTCACTATAGCCTCGACCTCCTGGACTCAAGCAATCCTCCTGCCTCAGCCTCCCAGTAGCTGGGACTACAGG
CGCATGCCACCATGCCTGGCTAATTTTAAATTTTTTTTTTTCTCTTTTTTGAGATGGAATCTCACTCTGTCGCCCAGGCT
GGAGTGCAGTGGCGTGATCTCGGCTGACGGCAAGCTCCGCCTCCCAGGTTCACTCCATTCGCCTGCCTCAGCCTCCCAAG
TAGCTGGGACTACAGGCGCTGGGATTACAAACCCAAACCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCACCCGGCC
TGTTTTGTCTTTCAATAGCAAGAGTTGTGTTTGCTTCGCCCCTACCTTTAGTGGAAAAATGTATAAAATGGAGATATTGA
CCTCCACATTGGGGTGGTTAAATTATAGCATGTATGCAAAGGAGCTTCGCTAATTTAAGGCTTTTTTGAAAGAGAAGAAA
CTGAATAATCCATGTGTGTATATATATTTTAAAAGCCATGGTCATCTTTCCATATCAGTAAAGCTGAGGCTCCCTGGGAC
TGCAGAGTTGTCCATCACAGTCCATTATAAGTGCGCTGCTGGGCCAGGTGCAGTGGCTTGTGCCTGAATCCCAGCACTTT
GGGAGGCCAAGGCAGGAGGATTCATTGAGCCCAGGAGTTTTGAGGCGAGCCTGGGCAATGTGGCCAGACCTCATCTCTTC
AAAAAATACACAAAAAATTAGCCAGGCATGGTGGCACGTGCCTGTAGTCTCAGCTACTCAGGAGGCTGAGGTGGGAGGAT
CACTTTGAGCCTTGCAGGTCAAAGCTGCAGTAAGCCATGATCTTGCCACTGCATTCCAGCCTGGATGACAGAGCGAGACC
CTGTCTCTAAAAAAAAAAAAACCAAACGGTGCACTGTTTTCTTTTTTCTTATCAATTTATTATTTTTAAATTAAATTTTC
TTTTAATAATTTATAAATTATAAATTTATATTAAAAAATGACAAATTTTTATTACTTATACATGAGGTAAAACTTAGGAT
ATATAAAGTACATATTGAAAAGTAATTTTTTGGCTGGCACAGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGT
GGCGGGCAGATCACATGAGATCATGAGTTCGAGACCAACCTGACCAACATGGAGAGACCCCATCTCTACTAAAAATACAA
AATTAGCCGGGGTGGTGGCGCATGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCTCTTGAACCCGGGAG
GCAGAGGTTGCGGTGAGCCAAGATCGTGCCTTTGCACACCAGCCAAGGCAACAAGAGCGAAAGTCCGTCTCAAAAAAAAA
GTAATTTTTTTTAAGTTAACCTCTGTCAGCAAACAAATTTAACCCAATAAAGGTCTTTGTTTTTTAATGTAGTAGAGGAG
TTAGGGTTTATAAAAAATATGGTAGGGAAGGGGGTCCCTGGATTTGCTAATGTGATTGTCATTTGCCCCTTAGGAGAGAG
CTCTGTTAGCAGAATGAAAAAATTGGAAGCCAGATTCAGGGAGGGACTGGAAGCAAAAGAATTTCTGTTCGAGGAAGAGC
CTGATGTTTGCCAGGGTCTGTTTAACTGGACATGAAGAGGAAGGCTCTGGACTTTCCTCCAGGAGTTTCAGGAGAAAGGT
AGGGCAGTGGTTAAGAGCAGAGCTCTGCCTAGACTAGCTGGGGTGCCTAGACTAGCTGGGGTGCCCAGACTAGCTGGGGT
GCCTAGACTAGCTGGGTACTTTGAGTGGCTCCTTCAGCCTGGACCTCGGTTTCCTCACCTGTATAGTAGAGATATGGGAG
CACCCAGCGCAGGATCACTGTGAACATAAATCAGTTAATGGAGGAAGCAGGTAGAGTGGTGCTGGGTGCATACCAAGCAC
TCCGTCAGTGTTTCCTGTTATTCGATGATTAGGAGGCAGCTTAAACTAGAGGGAGTTGAGCTGAATCAGGATGTTTGTCC
CAGGTAGCTGGGAATCTGCCTAGCCCAGTGCCCAGTTTATTTAGGTGCTCTCTCAGTGTTCCCTGATTGTTTTTTCCTTT
GTCATCTTATCTACAGGATGTGACTGGGAAGCTCTGGTTTCAGTGTCATGTGTCTATTCTTTATTTCCAGGCAAAGGAAA
CCAACAATAAGAAGAAAGAATTTGAGGAAACTGCGGAGAAAGTGCGCCGTGCCATCGAGCAGCTGGCTGCCATGGATTGA
GGCCTCTGGCCGGAGCTGCCTGGTCCCAGAGTGGCTGCACCACTTCCAGGGTTTATTCCCTGGTGCCACCAGCCTTCCTG
TGGGCCCCTTAGCAATGTCTTAGGAAAGGAGATCAACATTTTCAAATTAGATGTTTCAACTGTGCTCTTGTTTTGTCTTG
AAAGTGGCACCAGAGGTGCTTCTGCCTGTGCAGCGGGTGCTGCTGGTAACAGTGGCTGCTTCTCTCTCTCTCTCTCTTTT
TTGGGGGCTCATTTTTGCTGTTTTGATTCCCGGGCTTACCAGGTGAGAAGTGAGGGAGGAAGAAGGCAGTGTCCCTTTTG
CTAGAGCTGACAGCTTTGTTCGCGTGGGCAGAGCCTTCCACAGTGAATGTGTCTGGACCTCATGTTGTTGAGGCTGTCAC
AGTCCTGAGTGTGGACTTGGCAGGTGCCTGTTGAATCTGAGCTGCAGGTTCCTTATCTGTCACACCTGTGCCTCCTCAGA
GGACAGTTTTTTTGTTGTTGTGTTTTTTTGTTTTTTTTTTTTTGGTAGATGCATGACTTGTGTGTGATGAGAGAATGGAG
ACAGAGTCCCTGGCTCCTCTACTGTTTAACAACATGGCTTTCTTATTTTGTTTGAATTGTTAATTCACAGAATAGCACAA
ACTACAATTAAAACTAAGCACAAAGCCATTCTAAGTCATTGGGGAAACGGGGTGAACTTCAGGTGGATGAGGAGACAGAA
TAGAGTGATAGGAAGCGTCTGGCAGATACTCCTTTTGCCACTGCTGTGTGATTAGACAGGCCCAGTGAGCCGCGGGGCAC
ATGCTGGCCGCTCCTCCCTCAGAAAAAGGCAGTGGCCTAAATCCTTTTTAAATGACTTGGCTCGATGCTGTGGGGGACTG
GCTGGGCTGCTGCAGGCCGTGTGTCTGTCAGCCCAACCTTCACATCTGTCACGTTCTCCACACGGGGGAGAGACGCAGTC
CGCCCAGGTCCCCGCTTTCTTTGGAGGCAGCAGCTCCCGCAGGGCTGAAGTCTGGCGTAAGATGATGGATTTGATTCGCC
CTCCTCCCTGTCATAGAGCTGCAGGGTGGATTGTTACAGCTTCGCTGGAAACCTCTGGAGGTCATCTCGGCTGTTCCTGA
GAAATAAAAAGCCTGTCATTTCAAACACTGCTGTGGACCCTACTGGGTTTTTAAAATATTGTCAGTTTTTCATCGTCGTC
CCTAGCCTGCCAACAGCCATCTGCCCAGACAGCCGCAGTGAGGATGAGCGTCCTGGCAGAGACGCAGTTGTCTCTGGGCG
CTTGCCAGAGCCACGAACCCCAGACCTGTTTGTATCATCCGGGCTCCTTCCGGGCAGAAACAACTGAAAATGCACTTCAG
ACCCACTTATTTCTGCCACATCTGAGTCGGCCTGAGATAGACTTTTCCCTCTAAACTGGGAGAATATCACAGTGGTTTTT
GTTAGCAGAAAATGCACTCCAGCCTCTGTACTCATCTAAGCTGCTTATTTTTGATATTTGTGTCAGTCTGTAAATGGATA
CTTCACTTTAATAACTGTTGCTTAGTAATTGGCTTTGTAGAGAAGCTGGAAAAAAATGGTTTTGTCTTCAACTCCTTTGC
ATGCCAGGCGGTGATGTGGATCTCGGCTTCTGTGAGCCTGTGCTGTGGGCAGGGCTGAGCTGGAGCCGCCCCTCTCAGCC
CGCCTGCCACGGCCTTTCCTTAAAGGCCATCCTTAAAACCAGACCCTCATGGCTACCAGCACCTGAAAGCTTCCTCGACA
TCTGTTAATAAAGCCGTAGGCCCTTGTCTAAGTGCAACCGCCTAGACTTTCTTTCAGATACATGTCCACATGTCCATTTT
TCAGGTTCTCTAAGTTGGAGTGGAGTCTGGGAAGGGTTGTGAATGAGGCTTCTGGGCTATGGGTGAGGTTCCAATGGCAG
GTTAGAGCCCCTCGGGCCAACTGCCATCCTGGAAAGTAGAGACAGCAGTGCCCGCTGCCCAGAAGAGACCAGCAAGCCAA
ACTGGAGCCCCCATTGCAGGCTGTCGCCATGTGGAAAGAGTAACTCACAATTGCCAATAAAGTCTCATGTGGTTTTATCT
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Primary source |
RefSeq : NM_001168.2 (GI:59859877)
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Name |
Baculoviral IAP repeat-containing 5 (BIRC5), transcript variant 1
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Type of transcript |
mRNA
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Organism |
Homo sapiens
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Length |
2655 nt
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Map |
17q25
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Location |
Chromosome 17 (NC_000017.10) strand : +
76210276...76210507 | 76210760...76210869 | 76212744...76212861 | 76219545...76221715 |
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Exon(s) |
Start |
End |
Length |
is coding |
Exon 1
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1
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232
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232
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1
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Exon 2
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233
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342
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110
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1
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Exon 4
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343
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460
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118
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1
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Exon 5
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461
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2631
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2171
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1
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Primary source |
NCBI : CCDS11755
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Nucleotide |
BIRC5, mRNA isoform 1[NM_001168.2] : 122...550
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Length |
429
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Location |
Chromosome 17 (NC_000017.10) strand : +
76210397...76210507 | 76210760...76210869 | 76212744...76212861 | 76219545...76219634 |
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Start codon |
1
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Translation |
NP_001159.2 |
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1 |
CCCAGAAGGC |
CGCGGGGGGT |
GGACCGCCTA |
AGAGGGCGTG |
CGCTCCCGAC |
ATGCCCCGCG |
GCGCGCCATT |
AACCGCCAGA |
|
81 |
TTTGAATCGC |
GGGACCCGTT |
GGCAGAGGTG |
GCGGCGGCGG |
CATGGGTGCC |
CCGACGTTGC |
CCCCTGCCTG |
GCAGCCCTTT |
|
161 |
CTCAAGGACC |
ACCGCATCTC |
TACATTCAAG |
AACTGGCCCT |
TCTTGGAGGG |
CTGCGCCTGC |
ACCCCGGAGC |
GGATGGCCGA |
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241 |
GGCTGGCTTC |
ATCCACTGCC |
CCACTGAGAA |
CGAGCCAGAC |
TTGGCCCAGT |
GTTTCTTCTG |
CTTCAAGGAG |
CTGGAAGGCT |
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321 |
GGGAGCCAGA |
TGACGACCCC |
ATAGAGGAAC |
ATAAAAAGCA |
TTCGTCCGGT |
TGCGCTTTCC |
TTTCTGTCAA |
GAAGCAGTTT |
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401 |
GAAGAATTAA |
CCCTTGGTGA |
ATTTTTGAAA |
CTGGACAGAG |
AAAGAGCCAA |
GAACAAAATT |
GCAAAGGAAA |
CCAACAATAA |
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481 |
GAAGAAAGAA |
TTTGAGGAAA |
CTGCGGAGAA |
AGTGCGCCGT |
GCCATCGAGC |
AGCTGGCTGC |
CATGGATTGA |
GGCCTCTGGC |
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561 |
CGGAGCTGCC |
TGGTCCCAGA |
GTGGCTGCAC |
CACTTCCAGG |
GTTTATTCCC |
TGGTGCCACC |
AGCCTTCCTG |
TGGGCCCCTT |
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641 |
AGCAATGTCT |
TAGGAAAGGA |
GATCAACATT |
TTCAAATTAG |
ATGTTTCAAC |
TGTGCTCTTG |
TTTTGTCTTG |
AAAGTGGCAC |
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721 |
CAGAGGTGCT |
TCTGCCTGTG |
CAGCGGGTGC |
TGCTGGTAAC |
AGTGGCTGCT |
TCTCTCTCTC |
TCTCTCTTTT |
TTGGGGGCTC |
|
801 |
ATTTTTGCTG |
TTTTGATTCC |
CGGGCTTACC |
AGGTGAGAAG |
TGAGGGAGGA |
AGAAGGCAGT |
GTCCCTTTTG |
CTAGAGCTGA |
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881 |
CAGCTTTGTT |
CGCGTGGGCA |
GAGCCTTCCA |
CAGTGAATGT |
GTCTGGACCT |
CATGTTGTTG |
AGGCTGTCAC |
AGTCCTGAGT |
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961 |
GTGGACTTGG |
CAGGTGCCTG |
TTGAATCTGA |
GCTGCAGGTT |
CCTTATCTGT |
CACACCTGTG |
CCTCCTCAGA |
GGACAGTTTT |
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1041 |
TTTGTTGTTG |
TGTTTTTTTG |
TTTTTTTTTT |
TTTGGTAGAT |
GCATGACTTG |
TGTGTGATGA |
GAGAATGGAG |
ACAGAGTCCC |
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1121 |
TGGCTCCTCT |
ACTGTTTAAC |
AACATGGCTT |
TCTTATTTTG |
TTTGAATTGT |
TAATTCACAG |
AATAGCACAA |
ACTACAATTA |
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1201 |
AAACTAAGCA |
CAAAGCCATT |
CTAAGTCATT |
GGGGAAACGG |
GGTGAACTTC |
AGGTGGATGA |
GGAGACAGAA |
TAGAGTGATA |
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1281 |
GGAAGCGTCT |
GGCAGATACT |
CCTTTTGCCA |
CTGCTGTGTG |
ATTAGACAGG |
CCCAGTGAGC |
CGCGGGGCAC |
ATGCTGGCCG |
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1361 |
CTCCTCCCTC |
AGAAAAAGGC |
AGTGGCCTAA |
ATCCTTTTTA |
AATGACTTGG |
CTCGATGCTG |
TGGGGGACTG |
GCTGGGCTGC |
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1441 |
TGCAGGCCGT |
GTGTCTGTCA |
GCCCAACCTT |
CACATCTGTC |
ACGTTCTCCA |
CACGGGGGAG |
AGACGCAGTC |
CGCCCAGGTC |
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1521 |
CCCGCTTTCT |
TTGGAGGCAG |
CAGCTCCCGC |
AGGGCTGAAG |
TCTGGCGTAA |
GATGATGGAT |
TTGATTCGCC |
CTCCTCCCTG |
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1601 |
TCATAGAGCT |
GCAGGGTGGA |
TTGTTACAGC |
TTCGCTGGAA |
ACCTCTGGAG |
GTCATCTCGG |
CTGTTCCTGA |
GAAATAAAAA |
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1681 |
GCCTGTCATT |
TCAAACACTG |
CTGTGGACCC |
TACTGGGTTT |
TTAAAATATT |
GTCAGTTTTT |
CATCGTCGTC |
CCTAGCCTGC |
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1761 |
CAACAGCCAT |
CTGCCCAGAC |
AGCCGCAGTG |
AGGATGAGCG |
TCCTGGCAGA |
GACGCAGTTG |
TCTCTGGGCG |
CTTGCCAGAG |
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1841 |
CCACGAACCC |
CAGACCTGTT |
TGTATCATCC |
GGGCTCCTTC |
CGGGCAGAAA |
CAACTGAAAA |
TGCACTTCAG |
ACCCACTTAT |
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1921 |
TTCTGCCACA |
TCTGAGTCGG |
CCTGAGATAG |
ACTTTTCCCT |
CTAAACTGGG |
AGAATATCAC |
AGTGGTTTTT |
GTTAGCAGAA |
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2001 |
AATGCACTCC |
AGCCTCTGTA |
CTCATCTAAG |
CTGCTTATTT |
TTGATATTTG |
TGTCAGTCTG |
TAAATGGATA |
CTTCACTTTA |
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2081 |
ATAACTGTTG |
CTTAGTAATT |
GGCTTTGTAG |
AGAAGCTGGA |
AAAAAATGGT |
TTTGTCTTCA |
ACTCCTTTGC |
ATGCCAGGCG |
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2161 |
GTGATGTGGA |
TCTCGGCTTC |
TGTGAGCCTG |
TGCTGTGGGC |
AGGGCTGAGC |
TGGAGCCGCC |
CCTCTCAGCC |
CGCCTGCCAC |
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2241 |
GGCCTTTCCT |
TAAAGGCCAT |
CCTTAAAACC |
AGACCCTCAT |
GGCTACCAGC |
ACCTGAAAGC |
TTCCTCGACA |
TCTGTTAATA |
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2321 |
AAGCCGTAGG |
CCCTTGTCTA |
AGTGCAACCG |
CCTAGACTTT |
CTTTCAGATA |
CATGTCCACA |
TGTCCATTTT |
TCAGGTTCTC |
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2401 |
TAAGTTGGAG |
TGGAGTCTGG |
GAAGGGTTGT |
GAATGAGGCT |
TCTGGGCTAT |
GGGTGAGGTT |
CCAATGGCAG |
GTTAGAGCCC |
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2481 |
CTCGGGCCAA |
CTGCCATCCT |
GGAAAGTAGA |
GACAGCAGTG |
CCCGCTGCCC |
AGAAGAGACC |
AGCAAGCCAA |
ACTGGAGCCC |
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2561 |
CCATTGCAGG |
CTGTCGCCAT |
GTGGAAAGAG |
TAACTCACAA |
TTGCCAATAA |
AGTCTCATGT |
GGTTTTATCT |
AAAAAAAAAA |
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2641 |
AAAAAAAAAA |
AAAAA |
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>gi|59859877|ref|NM_001168.2|Baculoviral IAP repeat-containing 5 (BIRC5), transcript variant 1
CCCAGAAGGCCGCGGGGGGTGGACCGCCTAAGAGGGCGTGCGCTCCCGACATGCCCCGCGGCGCGCCATTAACCGCCAGA
TTTGAATCGCGGGACCCGTTGGCAGAGGTGGCGGCGGCGGCATGGGTGCCCCGACGTTGCCCCCTGCCTGGCAGCCCTTT
CTCAAGGACCACCGCATCTCTACATTCAAGAACTGGCCCTTCTTGGAGGGCTGCGCCTGCACCCCGGAGCGGATGGCCGA
GGCTGGCTTCATCCACTGCCCCACTGAGAACGAGCCAGACTTGGCCCAGTGTTTCTTCTGCTTCAAGGAGCTGGAAGGCT
GGGAGCCAGATGACGACCCCATAGAGGAACATAAAAAGCATTCGTCCGGTTGCGCTTTCCTTTCTGTCAAGAAGCAGTTT
GAAGAATTAACCCTTGGTGAATTTTTGAAACTGGACAGAGAAAGAGCCAAGAACAAAATTGCAAAGGAAACCAACAATAA
GAAGAAAGAATTTGAGGAAACTGCGGAGAAAGTGCGCCGTGCCATCGAGCAGCTGGCTGCCATGGATTGAGGCCTCTGGC
CGGAGCTGCCTGGTCCCAGAGTGGCTGCACCACTTCCAGGGTTTATTCCCTGGTGCCACCAGCCTTCCTGTGGGCCCCTT
AGCAATGTCTTAGGAAAGGAGATCAACATTTTCAAATTAGATGTTTCAACTGTGCTCTTGTTTTGTCTTGAAAGTGGCAC
CAGAGGTGCTTCTGCCTGTGCAGCGGGTGCTGCTGGTAACAGTGGCTGCTTCTCTCTCTCTCTCTCTTTTTTGGGGGCTC
ATTTTTGCTGTTTTGATTCCCGGGCTTACCAGGTGAGAAGTGAGGGAGGAAGAAGGCAGTGTCCCTTTTGCTAGAGCTGA
CAGCTTTGTTCGCGTGGGCAGAGCCTTCCACAGTGAATGTGTCTGGACCTCATGTTGTTGAGGCTGTCACAGTCCTGAGT
GTGGACTTGGCAGGTGCCTGTTGAATCTGAGCTGCAGGTTCCTTATCTGTCACACCTGTGCCTCCTCAGAGGACAGTTTT
TTTGTTGTTGTGTTTTTTTGTTTTTTTTTTTTTGGTAGATGCATGACTTGTGTGTGATGAGAGAATGGAGACAGAGTCCC
TGGCTCCTCTACTGTTTAACAACATGGCTTTCTTATTTTGTTTGAATTGTTAATTCACAGAATAGCACAAACTACAATTA
AAACTAAGCACAAAGCCATTCTAAGTCATTGGGGAAACGGGGTGAACTTCAGGTGGATGAGGAGACAGAATAGAGTGATA
GGAAGCGTCTGGCAGATACTCCTTTTGCCACTGCTGTGTGATTAGACAGGCCCAGTGAGCCGCGGGGCACATGCTGGCCG
CTCCTCCCTCAGAAAAAGGCAGTGGCCTAAATCCTTTTTAAATGACTTGGCTCGATGCTGTGGGGGACTGGCTGGGCTGC
TGCAGGCCGTGTGTCTGTCAGCCCAACCTTCACATCTGTCACGTTCTCCACACGGGGGAGAGACGCAGTCCGCCCAGGTC
CCCGCTTTCTTTGGAGGCAGCAGCTCCCGCAGGGCTGAAGTCTGGCGTAAGATGATGGATTTGATTCGCCCTCCTCCCTG
TCATAGAGCTGCAGGGTGGATTGTTACAGCTTCGCTGGAAACCTCTGGAGGTCATCTCGGCTGTTCCTGAGAAATAAAAA
GCCTGTCATTTCAAACACTGCTGTGGACCCTACTGGGTTTTTAAAATATTGTCAGTTTTTCATCGTCGTCCCTAGCCTGC
CAACAGCCATCTGCCCAGACAGCCGCAGTGAGGATGAGCGTCCTGGCAGAGACGCAGTTGTCTCTGGGCGCTTGCCAGAG
CCACGAACCCCAGACCTGTTTGTATCATCCGGGCTCCTTCCGGGCAGAAACAACTGAAAATGCACTTCAGACCCACTTAT
TTCTGCCACATCTGAGTCGGCCTGAGATAGACTTTTCCCTCTAAACTGGGAGAATATCACAGTGGTTTTTGTTAGCAGAA
AATGCACTCCAGCCTCTGTACTCATCTAAGCTGCTTATTTTTGATATTTGTGTCAGTCTGTAAATGGATACTTCACTTTA
ATAACTGTTGCTTAGTAATTGGCTTTGTAGAGAAGCTGGAAAAAAATGGTTTTGTCTTCAACTCCTTTGCATGCCAGGCG
GTGATGTGGATCTCGGCTTCTGTGAGCCTGTGCTGTGGGCAGGGCTGAGCTGGAGCCGCCCCTCTCAGCCCGCCTGCCAC
GGCCTTTCCTTAAAGGCCATCCTTAAAACCAGACCCTCATGGCTACCAGCACCTGAAAGCTTCCTCGACATCTGTTAATA
AAGCCGTAGGCCCTTGTCTAAGTGCAACCGCCTAGACTTTCTTTCAGATACATGTCCACATGTCCATTTTTCAGGTTCTC
TAAGTTGGAGTGGAGTCTGGGAAGGGTTGTGAATGAGGCTTCTGGGCTATGGGTGAGGTTCCAATGGCAGGTTAGAGCCC
CTCGGGCCAACTGCCATCCTGGAAAGTAGAGACAGCAGTGCCCGCTGCCCAGAAGAGACCAGCAAGCCAAACTGGAGCCC
CCATTGCAGGCTGTCGCCATGTGGAAAGAGTAACTCACAATTGCCAATAAAGTCTCATGTGGTTTTATCTAAAAAAAAAA
AAAAAAAAAAAAAAA
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Primary source |
RefSeq : NM_001012270.1 (GI:59859879)
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Name |
Baculoviral IAP repeat-containing 5 (BIRC5), transcript variant 2
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Type of transcript |
mRNA
|
Organism |
Homo sapiens
|
Length |
2537 nt
|
Map |
17q25
|
Location |
Chromosome 17 (NC_000017.10) strand : +
76210276...76210507 | 76210760...76210869 | 76219545...76221715 |
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Exon(s) |
Start |
End |
Length |
is coding |
Exon 1
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1
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232
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232
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1
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Exon 2
|
233
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342
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110
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1
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Exon 5
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343
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2513
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2171
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1
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ID |
Class |
Location |
Mutation |
Length |
is synonymous |
Source |
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Primary source |
NCBI : CCDS32751
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Nucleotide |
BIRC5, mRNA isoform 2[NM_001012270.1] : 122...535
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Length |
414
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Location |
Chromosome 17 (NC_000017.10) strand : +
76210397...76210507 | 76210760...76210869 | 76219545...76219737 |
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Start codon |
1
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Translation |
NP_001012270.1 |
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1 |
CCCAGAAGGC |
CGCGGGGGGT |
GGACCGCCTA |
AGAGGGCGTG |
CGCTCCCGAC |
ATGCCCCGCG |
GCGCGCCATT |
AACCGCCAGA |
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81 |
TTTGAATCGC |
GGGACCCGTT |
GGCAGAGGTG |
GCGGCGGCGG |
CATGGGTGCC |
CCGACGTTGC |
CCCCTGCCTG |
GCAGCCCTTT |
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161 |
CTCAAGGACC |
ACCGCATCTC |
TACATTCAAG |
AACTGGCCCT |
TCTTGGAGGG |
CTGCGCCTGC |
ACCCCGGAGC |
GGATGGCCGA |
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241 |
GGCTGGCTTC |
ATCCACTGCC |
CCACTGAGAA |
CGAGCCAGAC |
TTGGCCCAGT |
GTTTCTTCTG |
CTTCAAGGAG |
CTGGAAGGCT |
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321 |
GGGAGCCAGA |
TGACGACCCC |
ATGCAAAGGA |
AACCAACAAT |
AAGAAGAAAG |
AATTTGAGGA |
AACTGCGGAG |
AAAGTGCGCC |
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401 |
GTGCCATCGA |
GCAGCTGGCT |
GCCATGGATT |
GAGGCCTCTG |
GCCGGAGCTG |
CCTGGTCCCA |
GAGTGGCTGC |
ACCACTTCCA |
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481 |
GGGTTTATTC |
CCTGGTGCCA |
CCAGCCTTCC |
TGTGGGCCCC |
TTAGCAATGT |
CTTAGGAAAG |
GAGATCAACA |
TTTTCAAATT |
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561 |
AGATGTTTCA |
ACTGTGCTCT |
TGTTTTGTCT |
TGAAAGTGGC |
ACCAGAGGTG |
CTTCTGCCTG |
TGCAGCGGGT |
GCTGCTGGTA |
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641 |
ACAGTGGCTG |
CTTCTCTCTC |
TCTCTCTCTT |
TTTTGGGGGC |
TCATTTTTGC |
TGTTTTGATT |
CCCGGGCTTA |
CCAGGTGAGA |
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721 |
AGTGAGGGAG |
GAAGAAGGCA |
GTGTCCCTTT |
TGCTAGAGCT |
GACAGCTTTG |
TTCGCGTGGG |
CAGAGCCTTC |
CACAGTGAAT |
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801 |
GTGTCTGGAC |
CTCATGTTGT |
TGAGGCTGTC |
ACAGTCCTGA |
GTGTGGACTT |
GGCAGGTGCC |
TGTTGAATCT |
GAGCTGCAGG |
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881 |
TTCCTTATCT |
GTCACACCTG |
TGCCTCCTCA |
GAGGACAGTT |
TTTTTGTTGT |
TGTGTTTTTT |
TGTTTTTTTT |
TTTTTGGTAG |
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961 |
ATGCATGACT |
TGTGTGTGAT |
GAGAGAATGG |
AGACAGAGTC |
CCTGGCTCCT |
CTACTGTTTA |
ACAACATGGC |
TTTCTTATTT |
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1041 |
TGTTTGAATT |
GTTAATTCAC |
AGAATAGCAC |
AAACTACAAT |
TAAAACTAAG |
CACAAAGCCA |
TTCTAAGTCA |
TTGGGGAAAC |
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1121 |
GGGGTGAACT |
TCAGGTGGAT |
GAGGAGACAG |
AATAGAGTGA |
TAGGAAGCGT |
CTGGCAGATA |
CTCCTTTTGC |
CACTGCTGTG |
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1201 |
TGATTAGACA |
GGCCCAGTGA |
GCCGCGGGGC |
ACATGCTGGC |
CGCTCCTCCC |
TCAGAAAAAG |
GCAGTGGCCT |
AAATCCTTTT |
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1281 |
TAAATGACTT |
GGCTCGATGC |
TGTGGGGGAC |
TGGCTGGGCT |
GCTGCAGGCC |
GTGTGTCTGT |
CAGCCCAACC |
TTCACATCTG |
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1361 |
TCACGTTCTC |
CACACGGGGG |
AGAGACGCAG |
TCCGCCCAGG |
TCCCCGCTTT |
CTTTGGAGGC |
AGCAGCTCCC |
GCAGGGCTGA |
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1441 |
AGTCTGGCGT |
AAGATGATGG |
ATTTGATTCG |
CCCTCCTCCC |
TGTCATAGAG |
CTGCAGGGTG |
GATTGTTACA |
GCTTCGCTGG |
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1521 |
AAACCTCTGG |
AGGTCATCTC |
GGCTGTTCCT |
GAGAAATAAA |
AAGCCTGTCA |
TTTCAAACAC |
TGCTGTGGAC |
CCTACTGGGT |
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1601 |
TTTTAAAATA |
TTGTCAGTTT |
TTCATCGTCG |
TCCCTAGCCT |
GCCAACAGCC |
ATCTGCCCAG |
ACAGCCGCAG |
TGAGGATGAG |
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1681 |
CGTCCTGGCA |
GAGACGCAGT |
TGTCTCTGGG |
CGCTTGCCAG |
AGCCACGAAC |
CCCAGACCTG |
TTTGTATCAT |
CCGGGCTCCT |
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1761 |
TCCGGGCAGA |
AACAACTGAA |
AATGCACTTC |
AGACCCACTT |
ATTTCTGCCA |
CATCTGAGTC |
GGCCTGAGAT |
AGACTTTTCC |
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1841 |
CTCTAAACTG |
GGAGAATATC |
ACAGTGGTTT |
TTGTTAGCAG |
AAAATGCACT |
CCAGCCTCTG |
TACTCATCTA |
AGCTGCTTAT |
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1921 |
TTTTGATATT |
TGTGTCAGTC |
TGTAAATGGA |
TACTTCACTT |
TAATAACTGT |
TGCTTAGTAA |
TTGGCTTTGT |
AGAGAAGCTG |
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2001 |
GAAAAAAATG |
GTTTTGTCTT |
CAACTCCTTT |
GCATGCCAGG |
CGGTGATGTG |
GATCTCGGCT |
TCTGTGAGCC |
TGTGCTGTGG |
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2081 |
GCAGGGCTGA |
GCTGGAGCCG |
CCCCTCTCAG |
CCCGCCTGCC |
ACGGCCTTTC |
CTTAAAGGCC |
ATCCTTAAAA |
CCAGACCCTC |
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2161 |
ATGGCTACCA |
GCACCTGAAA |
GCTTCCTCGA |
CATCTGTTAA |
TAAAGCCGTA |
GGCCCTTGTC |
TAAGTGCAAC |
CGCCTAGACT |
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2241 |
TTCTTTCAGA |
TACATGTCCA |
CATGTCCATT |
TTTCAGGTTC |
TCTAAGTTGG |
AGTGGAGTCT |
GGGAAGGGTT |
GTGAATGAGG |
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2321 |
CTTCTGGGCT |
ATGGGTGAGG |
TTCCAATGGC |
AGGTTAGAGC |
CCCTCGGGCC |
AACTGCCATC |
CTGGAAAGTA |
GAGACAGCAG |
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2401 |
TGCCCGCTGC |
CCAGAAGAGA |
CCAGCAAGCC |
AAACTGGAGC |
CCCCATTGCA |
GGCTGTCGCC |
ATGTGGAAAG |
AGTAACTCAC |
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2481 |
AATTGCCAAT |
AAAGTCTCAT |
GTGGTTTTAT |
CTAAAAAAAA |
AAAAAAAAAA |
AAAAAAA |
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>gi|59859879|ref|NM_001012270.1|Baculoviral IAP repeat-containing 5 (BIRC5), transcript variant 2
CCCAGAAGGCCGCGGGGGGTGGACCGCCTAAGAGGGCGTGCGCTCCCGACATGCCCCGCGGCGCGCCATTAACCGCCAGA
TTTGAATCGCGGGACCCGTTGGCAGAGGTGGCGGCGGCGGCATGGGTGCCCCGACGTTGCCCCCTGCCTGGCAGCCCTTT
CTCAAGGACCACCGCATCTCTACATTCAAGAACTGGCCCTTCTTGGAGGGCTGCGCCTGCACCCCGGAGCGGATGGCCGA
GGCTGGCTTCATCCACTGCCCCACTGAGAACGAGCCAGACTTGGCCCAGTGTTTCTTCTGCTTCAAGGAGCTGGAAGGCT
GGGAGCCAGATGACGACCCCATGCAAAGGAAACCAACAATAAGAAGAAAGAATTTGAGGAAACTGCGGAGAAAGTGCGCC
GTGCCATCGAGCAGCTGGCTGCCATGGATTGAGGCCTCTGGCCGGAGCTGCCTGGTCCCAGAGTGGCTGCACCACTTCCA
GGGTTTATTCCCTGGTGCCACCAGCCTTCCTGTGGGCCCCTTAGCAATGTCTTAGGAAAGGAGATCAACATTTTCAAATT
AGATGTTTCAACTGTGCTCTTGTTTTGTCTTGAAAGTGGCACCAGAGGTGCTTCTGCCTGTGCAGCGGGTGCTGCTGGTA
ACAGTGGCTGCTTCTCTCTCTCTCTCTCTTTTTTGGGGGCTCATTTTTGCTGTTTTGATTCCCGGGCTTACCAGGTGAGA
AGTGAGGGAGGAAGAAGGCAGTGTCCCTTTTGCTAGAGCTGACAGCTTTGTTCGCGTGGGCAGAGCCTTCCACAGTGAAT
GTGTCTGGACCTCATGTTGTTGAGGCTGTCACAGTCCTGAGTGTGGACTTGGCAGGTGCCTGTTGAATCTGAGCTGCAGG
TTCCTTATCTGTCACACCTGTGCCTCCTCAGAGGACAGTTTTTTTGTTGTTGTGTTTTTTTGTTTTTTTTTTTTTGGTAG
ATGCATGACTTGTGTGTGATGAGAGAATGGAGACAGAGTCCCTGGCTCCTCTACTGTTTAACAACATGGCTTTCTTATTT
TGTTTGAATTGTTAATTCACAGAATAGCACAAACTACAATTAAAACTAAGCACAAAGCCATTCTAAGTCATTGGGGAAAC
GGGGTGAACTTCAGGTGGATGAGGAGACAGAATAGAGTGATAGGAAGCGTCTGGCAGATACTCCTTTTGCCACTGCTGTG
TGATTAGACAGGCCCAGTGAGCCGCGGGGCACATGCTGGCCGCTCCTCCCTCAGAAAAAGGCAGTGGCCTAAATCCTTTT
TAAATGACTTGGCTCGATGCTGTGGGGGACTGGCTGGGCTGCTGCAGGCCGTGTGTCTGTCAGCCCAACCTTCACATCTG
TCACGTTCTCCACACGGGGGAGAGACGCAGTCCGCCCAGGTCCCCGCTTTCTTTGGAGGCAGCAGCTCCCGCAGGGCTGA
AGTCTGGCGTAAGATGATGGATTTGATTCGCCCTCCTCCCTGTCATAGAGCTGCAGGGTGGATTGTTACAGCTTCGCTGG
AAACCTCTGGAGGTCATCTCGGCTGTTCCTGAGAAATAAAAAGCCTGTCATTTCAAACACTGCTGTGGACCCTACTGGGT
TTTTAAAATATTGTCAGTTTTTCATCGTCGTCCCTAGCCTGCCAACAGCCATCTGCCCAGACAGCCGCAGTGAGGATGAG
CGTCCTGGCAGAGACGCAGTTGTCTCTGGGCGCTTGCCAGAGCCACGAACCCCAGACCTGTTTGTATCATCCGGGCTCCT
TCCGGGCAGAAACAACTGAAAATGCACTTCAGACCCACTTATTTCTGCCACATCTGAGTCGGCCTGAGATAGACTTTTCC
CTCTAAACTGGGAGAATATCACAGTGGTTTTTGTTAGCAGAAAATGCACTCCAGCCTCTGTACTCATCTAAGCTGCTTAT
TTTTGATATTTGTGTCAGTCTGTAAATGGATACTTCACTTTAATAACTGTTGCTTAGTAATTGGCTTTGTAGAGAAGCTG
GAAAAAAATGGTTTTGTCTTCAACTCCTTTGCATGCCAGGCGGTGATGTGGATCTCGGCTTCTGTGAGCCTGTGCTGTGG
GCAGGGCTGAGCTGGAGCCGCCCCTCTCAGCCCGCCTGCCACGGCCTTTCCTTAAAGGCCATCCTTAAAACCAGACCCTC
ATGGCTACCAGCACCTGAAAGCTTCCTCGACATCTGTTAATAAAGCCGTAGGCCCTTGTCTAAGTGCAACCGCCTAGACT
TTCTTTCAGATACATGTCCACATGTCCATTTTTCAGGTTCTCTAAGTTGGAGTGGAGTCTGGGAAGGGTTGTGAATGAGG
CTTCTGGGCTATGGGTGAGGTTCCAATGGCAGGTTAGAGCCCCTCGGGCCAACTGCCATCCTGGAAAGTAGAGACAGCAG
TGCCCGCTGCCCAGAAGAGACCAGCAAGCCAAACTGGAGCCCCCATTGCAGGCTGTCGCCATGTGGAAAGAGTAACTCAC
AATTGCCAATAAAGTCTCATGTGGTTTTATCTAAAAAAAAAAAAAAAAAAAAAAAAA
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Primary source |
RefSeq : NM_001012271.1 (GI:59859881)
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Name |
Baculoviral IAP repeat-containing 5 (BIRC5), transcript variant 3
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Type of transcript |
mRNA
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Organism |
Homo sapiens
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Length |
2724 nt
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Map |
17q25
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Location |
Chromosome 17 (NC_000017.10) strand : +
76210276...76210507 | 76210760...76210869 | 76212046...76212114 | 76212744...76212861 |
76219545...76221715 |
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Exon(s) |
Start |
End |
Length |
is coding |
Exon 1
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1
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232
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232
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1
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Exon 2
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233
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342
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110
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1
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Exon 3
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343
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411
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69
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1
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Exon 4
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412
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529
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118
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1
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Exon 5
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530
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2700
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2171
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1
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ID |
Class |
Location |
Mutation |
Length |
is synonymous |
Source |
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Primary source |
NCBI : CCDS32752
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Nucleotide |
BIRC5, mRNA isoform 3[NM_001012271.1] : 122...619
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Length |
498
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Location |
Chromosome 17 (NC_000017.10) strand : +
76210397...76210507 | 76210760...76210869 | 76212046...76212114 | 76212744...76212861 |
76219545...76219634 |
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Start codon |
1
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Translation |
NP_001012271.1 |
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1 |
CCCAGAAGGC |
CGCGGGGGGT |
GGACCGCCTA |
AGAGGGCGTG |
CGCTCCCGAC |
ATGCCCCGCG |
GCGCGCCATT |
AACCGCCAGA |
|
81 |
TTTGAATCGC |
GGGACCCGTT |
GGCAGAGGTG |
GCGGCGGCGG |
CATGGGTGCC |
CCGACGTTGC |
CCCCTGCCTG |
GCAGCCCTTT |
|
161 |
CTCAAGGACC |
ACCGCATCTC |
TACATTCAAG |
AACTGGCCCT |
TCTTGGAGGG |
CTGCGCCTGC |
ACCCCGGAGC |
GGATGGCCGA |
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241 |
GGCTGGCTTC |
ATCCACTGCC |
CCACTGAGAA |
CGAGCCAGAC |
TTGGCCCAGT |
GTTTCTTCTG |
CTTCAAGGAG |
CTGGAAGGCT |
|
321 |
GGGAGCCAGA |
TGACGACCCC |
ATTGGGCCGG |
GCACGGTGGC |
TTACGCCTGT |
AATACCAGCA |
CTTTGGGAGG |
CCGAGGCGGG |
|
401 |
CGGATCACGA |
GAGAGGAACA |
TAAAAAGCAT |
TCGTCCGGTT |
GCGCTTTCCT |
TTCTGTCAAG |
AAGCAGTTTG |
AAGAATTAAC |
|
481 |
CCTTGGTGAA |
TTTTTGAAAC |
TGGACAGAGA |
AAGAGCCAAG |
AACAAAATTG |
CAAAGGAAAC |
CAACAATAAG |
AAGAAAGAAT |
|
561 |
TTGAGGAAAC |
TGCGGAGAAA |
GTGCGCCGTG |
CCATCGAGCA |
GCTGGCTGCC |
ATGGATTGAG |
GCCTCTGGCC |
GGAGCTGCCT |
|
641 |
GGTCCCAGAG |
TGGCTGCACC |
ACTTCCAGGG |
TTTATTCCCT |
GGTGCCACCA |
GCCTTCCTGT |
GGGCCCCTTA |
GCAATGTCTT |
|
721 |
AGGAAAGGAG |
ATCAACATTT |
TCAAATTAGA |
TGTTTCAACT |
GTGCTCTTGT |
TTTGTCTTGA |
AAGTGGCACC |
AGAGGTGCTT |
|
801 |
CTGCCTGTGC |
AGCGGGTGCT |
GCTGGTAACA |
GTGGCTGCTT |
CTCTCTCTCT |
CTCTCTTTTT |
TGGGGGCTCA |
TTTTTGCTGT |
|
881 |
TTTGATTCCC |
GGGCTTACCA |
GGTGAGAAGT |
GAGGGAGGAA |
GAAGGCAGTG |
TCCCTTTTGC |
TAGAGCTGAC |
AGCTTTGTTC |
|
961 |
GCGTGGGCAG |
AGCCTTCCAC |
AGTGAATGTG |
TCTGGACCTC |
ATGTTGTTGA |
GGCTGTCACA |
GTCCTGAGTG |
TGGACTTGGC |
|
1041 |
AGGTGCCTGT |
TGAATCTGAG |
CTGCAGGTTC |
CTTATCTGTC |
ACACCTGTGC |
CTCCTCAGAG |
GACAGTTTTT |
TTGTTGTTGT |
|
1121 |
GTTTTTTTGT |
TTTTTTTTTT |
TTGGTAGATG |
CATGACTTGT |
GTGTGATGAG |
AGAATGGAGA |
CAGAGTCCCT |
GGCTCCTCTA |
|
1201 |
CTGTTTAACA |
ACATGGCTTT |
CTTATTTTGT |
TTGAATTGTT |
AATTCACAGA |
ATAGCACAAA |
CTACAATTAA |
AACTAAGCAC |
|
1281 |
AAAGCCATTC |
TAAGTCATTG |
GGGAAACGGG |
GTGAACTTCA |
GGTGGATGAG |
GAGACAGAAT |
AGAGTGATAG |
GAAGCGTCTG |
|
1361 |
GCAGATACTC |
CTTTTGCCAC |
TGCTGTGTGA |
TTAGACAGGC |
CCAGTGAGCC |
GCGGGGCACA |
TGCTGGCCGC |
TCCTCCCTCA |
|
1441 |
GAAAAAGGCA |
GTGGCCTAAA |
TCCTTTTTAA |
ATGACTTGGC |
TCGATGCTGT |
GGGGGACTGG |
CTGGGCTGCT |
GCAGGCCGTG |
|
1521 |
TGTCTGTCAG |
CCCAACCTTC |
ACATCTGTCA |
CGTTCTCCAC |
ACGGGGGAGA |
GACGCAGTCC |
GCCCAGGTCC |
CCGCTTTCTT |
|
1601 |
TGGAGGCAGC |
AGCTCCCGCA |
GGGCTGAAGT |
CTGGCGTAAG |
ATGATGGATT |
TGATTCGCCC |
TCCTCCCTGT |
CATAGAGCTG |
|
1681 |
CAGGGTGGAT |
TGTTACAGCT |
TCGCTGGAAA |
CCTCTGGAGG |
TCATCTCGGC |
TGTTCCTGAG |
AAATAAAAAG |
CCTGTCATTT |
|
1761 |
CAAACACTGC |
TGTGGACCCT |
ACTGGGTTTT |
TAAAATATTG |
TCAGTTTTTC |
ATCGTCGTCC |
CTAGCCTGCC |
AACAGCCATC |
|
1841 |
TGCCCAGACA |
GCCGCAGTGA |
GGATGAGCGT |
CCTGGCAGAG |
ACGCAGTTGT |
CTCTGGGCGC |
TTGCCAGAGC |
CACGAACCCC |
|
1921 |
AGACCTGTTT |
GTATCATCCG |
GGCTCCTTCC |
GGGCAGAAAC |
AACTGAAAAT |
GCACTTCAGA |
CCCACTTATT |
TCTGCCACAT |
|
2001 |
CTGAGTCGGC |
CTGAGATAGA |
CTTTTCCCTC |
TAAACTGGGA |
GAATATCACA |
GTGGTTTTTG |
TTAGCAGAAA |
ATGCACTCCA |
|
2081 |
GCCTCTGTAC |
TCATCTAAGC |
TGCTTATTTT |
TGATATTTGT |
GTCAGTCTGT |
AAATGGATAC |
TTCACTTTAA |
TAACTGTTGC |
|
2161 |
TTAGTAATTG |
GCTTTGTAGA |
GAAGCTGGAA |
AAAAATGGTT |
TTGTCTTCAA |
CTCCTTTGCA |
TGCCAGGCGG |
TGATGTGGAT |
|
2241 |
CTCGGCTTCT |
GTGAGCCTGT |
GCTGTGGGCA |
GGGCTGAGCT |
GGAGCCGCCC |
CTCTCAGCCC |
GCCTGCCACG |
GCCTTTCCTT |
|
2321 |
AAAGGCCATC |
CTTAAAACCA |
GACCCTCATG |
GCTACCAGCA |
CCTGAAAGCT |
TCCTCGACAT |
CTGTTAATAA |
AGCCGTAGGC |
|
2401 |
CCTTGTCTAA |
GTGCAACCGC |
CTAGACTTTC |
TTTCAGATAC |
ATGTCCACAT |
GTCCATTTTT |
CAGGTTCTCT |
AAGTTGGAGT |
|
2481 |
GGAGTCTGGG |
AAGGGTTGTG |
AATGAGGCTT |
CTGGGCTATG |
GGTGAGGTTC |
CAATGGCAGG |
TTAGAGCCCC |
TCGGGCCAAC |
|
2561 |
TGCCATCCTG |
GAAAGTAGAG |
ACAGCAGTGC |
CCGCTGCCCA |
GAAGAGACCA |
GCAAGCCAAA |
CTGGAGCCCC |
CATTGCAGGC |
|
2641 |
TGTCGCCATG |
TGGAAAGAGT |
AACTCACAAT |
TGCCAATAAA |
GTCTCATGTG |
GTTTTATCTA |
AAAAAAAAAA |
AAAAAAAAAA |
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2721 |
AAAA |
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>gi|59859881|ref|NM_001012271.1|Baculoviral IAP repeat-containing 5 (BIRC5), transcript variant 3
CCCAGAAGGCCGCGGGGGGTGGACCGCCTAAGAGGGCGTGCGCTCCCGACATGCCCCGCGGCGCGCCATTAACCGCCAGA
TTTGAATCGCGGGACCCGTTGGCAGAGGTGGCGGCGGCGGCATGGGTGCCCCGACGTTGCCCCCTGCCTGGCAGCCCTTT
CTCAAGGACCACCGCATCTCTACATTCAAGAACTGGCCCTTCTTGGAGGGCTGCGCCTGCACCCCGGAGCGGATGGCCGA
GGCTGGCTTCATCCACTGCCCCACTGAGAACGAGCCAGACTTGGCCCAGTGTTTCTTCTGCTTCAAGGAGCTGGAAGGCT
GGGAGCCAGATGACGACCCCATTGGGCCGGGCACGGTGGCTTACGCCTGTAATACCAGCACTTTGGGAGGCCGAGGCGGG
CGGATCACGAGAGAGGAACATAAAAAGCATTCGTCCGGTTGCGCTTTCCTTTCTGTCAAGAAGCAGTTTGAAGAATTAAC
CCTTGGTGAATTTTTGAAACTGGACAGAGAAAGAGCCAAGAACAAAATTGCAAAGGAAACCAACAATAAGAAGAAAGAAT
TTGAGGAAACTGCGGAGAAAGTGCGCCGTGCCATCGAGCAGCTGGCTGCCATGGATTGAGGCCTCTGGCCGGAGCTGCCT
GGTCCCAGAGTGGCTGCACCACTTCCAGGGTTTATTCCCTGGTGCCACCAGCCTTCCTGTGGGCCCCTTAGCAATGTCTT
AGGAAAGGAGATCAACATTTTCAAATTAGATGTTTCAACTGTGCTCTTGTTTTGTCTTGAAAGTGGCACCAGAGGTGCTT
CTGCCTGTGCAGCGGGTGCTGCTGGTAACAGTGGCTGCTTCTCTCTCTCTCTCTCTTTTTTGGGGGCTCATTTTTGCTGT
TTTGATTCCCGGGCTTACCAGGTGAGAAGTGAGGGAGGAAGAAGGCAGTGTCCCTTTTGCTAGAGCTGACAGCTTTGTTC
GCGTGGGCAGAGCCTTCCACAGTGAATGTGTCTGGACCTCATGTTGTTGAGGCTGTCACAGTCCTGAGTGTGGACTTGGC
AGGTGCCTGTTGAATCTGAGCTGCAGGTTCCTTATCTGTCACACCTGTGCCTCCTCAGAGGACAGTTTTTTTGTTGTTGT
GTTTTTTTGTTTTTTTTTTTTTGGTAGATGCATGACTTGTGTGTGATGAGAGAATGGAGACAGAGTCCCTGGCTCCTCTA
CTGTTTAACAACATGGCTTTCTTATTTTGTTTGAATTGTTAATTCACAGAATAGCACAAACTACAATTAAAACTAAGCAC
AAAGCCATTCTAAGTCATTGGGGAAACGGGGTGAACTTCAGGTGGATGAGGAGACAGAATAGAGTGATAGGAAGCGTCTG
GCAGATACTCCTTTTGCCACTGCTGTGTGATTAGACAGGCCCAGTGAGCCGCGGGGCACATGCTGGCCGCTCCTCCCTCA
GAAAAAGGCAGTGGCCTAAATCCTTTTTAAATGACTTGGCTCGATGCTGTGGGGGACTGGCTGGGCTGCTGCAGGCCGTG
TGTCTGTCAGCCCAACCTTCACATCTGTCACGTTCTCCACACGGGGGAGAGACGCAGTCCGCCCAGGTCCCCGCTTTCTT
TGGAGGCAGCAGCTCCCGCAGGGCTGAAGTCTGGCGTAAGATGATGGATTTGATTCGCCCTCCTCCCTGTCATAGAGCTG
CAGGGTGGATTGTTACAGCTTCGCTGGAAACCTCTGGAGGTCATCTCGGCTGTTCCTGAGAAATAAAAAGCCTGTCATTT
CAAACACTGCTGTGGACCCTACTGGGTTTTTAAAATATTGTCAGTTTTTCATCGTCGTCCCTAGCCTGCCAACAGCCATC
TGCCCAGACAGCCGCAGTGAGGATGAGCGTCCTGGCAGAGACGCAGTTGTCTCTGGGCGCTTGCCAGAGCCACGAACCCC
AGACCTGTTTGTATCATCCGGGCTCCTTCCGGGCAGAAACAACTGAAAATGCACTTCAGACCCACTTATTTCTGCCACAT
CTGAGTCGGCCTGAGATAGACTTTTCCCTCTAAACTGGGAGAATATCACAGTGGTTTTTGTTAGCAGAAAATGCACTCCA
GCCTCTGTACTCATCTAAGCTGCTTATTTTTGATATTTGTGTCAGTCTGTAAATGGATACTTCACTTTAATAACTGTTGC
TTAGTAATTGGCTTTGTAGAGAAGCTGGAAAAAAATGGTTTTGTCTTCAACTCCTTTGCATGCCAGGCGGTGATGTGGAT
CTCGGCTTCTGTGAGCCTGTGCTGTGGGCAGGGCTGAGCTGGAGCCGCCCCTCTCAGCCCGCCTGCCACGGCCTTTCCTT
AAAGGCCATCCTTAAAACCAGACCCTCATGGCTACCAGCACCTGAAAGCTTCCTCGACATCTGTTAATAAAGCCGTAGGC
CCTTGTCTAAGTGCAACCGCCTAGACTTTCTTTCAGATACATGTCCACATGTCCATTTTTCAGGTTCTCTAAGTTGGAGT
GGAGTCTGGGAAGGGTTGTGAATGAGGCTTCTGGGCTATGGGTGAGGTTCCAATGGCAGGTTAGAGCCCCTCGGGCCAAC
TGCCATCCTGGAAAGTAGAGACAGCAGTGCCCGCTGCCCAGAAGAGACCAGCAAGCCAAACTGGAGCCCCCATTGCAGGC
TGTCGCCATGTGGAAAGAGTAACTCACAATTGCCAATAAAGTCTCATGTGGTTTTATCTAAAAAAAAAAAAAAAAAAAAA
AAAA
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Exon number |
5
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Length |
2171 nt
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Location |
Chromosome 17 (NC_000017.10) : 76219545...76221715 (+)
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Is part of |
BIRC5, mRNA isoform 1
(NM_001168.2)
BIRC5, mRNA isoform 2
(NM_001012270.1)
BIRC5, mRNA isoform 3
(NM_001012271.1)
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Sequence |
Show
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GCAAAGGAAACCAACAATAAGAAGAAAGAATTTGAGGAAACTGCGGAGAAAGTGCGCCGTGCCATCGAGCAGCTGGCTGC
CATGGATTGAGGCCTCTGGCCGGAGCTGCCTGGTCCCAGAGTGGCTGCACCACTTCCAGGGTTTATTCCCTGGTGCCACC
AGCCTTCCTGTGGGCCCCTTAGCAATGTCTTAGGAAAGGAGATCAACATTTTCAAATTAGATGTTTCAACTGTGCTCTTG
TTTTGTCTTGAAAGTGGCACCAGAGGTGCTTCTGCCTGTGCAGCGGGTGCTGCTGGTAACAGTGGCTGCTTCTCTCTCTC
TCTCTCTTTTTTGGGGGCTCATTTTTGCTGTTTTGATTCCCGGGCTTACCAGGTGAGAAGTGAGGGAGGAAGAAGGCAGT
GTCCCTTTTGCTAGAGCTGACAGCTTTGTTCGCGTGGGCAGAGCCTTCCACAGTGAATGTGTCTGGACCTCATGTTGTTG
AGGCTGTCACAGTCCTGAGTGTGGACTTGGCAGGTGCCTGTTGAATCTGAGCTGCAGGTTCCTTATCTGTCACACCTGTG
CCTCCTCAGAGGACAGTTTTTTTGTTGTTGTGTTTTTTTGTTTTTTTTTTTTTGGTAGATGCATGACTTGTGTGTGATGA
GAGAATGGAGACAGAGTCCCTGGCTCCTCTACTGTTTAACAACATGGCTTTCTTATTTTGTTTGAATTGTTAATTCACAG
AATAGCACAAACTACAATTAAAACTAAGCACAAAGCCATTCTAAGTCATTGGGGAAACGGGGTGAACTTCAGGTGGATGA
GGAGACAGAATAGAGTGATAGGAAGCGTCTGGCAGATACTCCTTTTGCCACTGCTGTGTGATTAGACAGGCCCAGTGAGC
CGCGGGGCACATGCTGGCCGCTCCTCCCTCAGAAAAAGGCAGTGGCCTAAATCCTTTTTAAATGACTTGGCTCGATGCTG
TGGGGGACTGGCTGGGCTGCTGCAGGCCGTGTGTCTGTCAGCCCAACCTTCACATCTGTCACGTTCTCCACACGGGGGAG
AGACGCAGTCCGCCCAGGTCCCCGCTTTCTTTGGAGGCAGCAGCTCCCGCAGGGCTGAAGTCTGGCGTAAGATGATGGAT
TTGATTCGCCCTCCTCCCTGTCATAGAGCTGCAGGGTGGATTGTTACAGCTTCGCTGGAAACCTCTGGAGGTCATCTCGG
CTGTTCCTGAGAAATAAAAAGCCTGTCATTTCAAACACTGCTGTGGACCCTACTGGGTTTTTAAAATATTGTCAGTTTTT
CATCGTCGTCCCTAGCCTGCCAACAGCCATCTGCCCAGACAGCCGCAGTGAGGATGAGCGTCCTGGCAGAGACGCAGTTG
TCTCTGGGCGCTTGCCAGAGCCACGAACCCCAGACCTGTTTGTATCATCCGGGCTCCTTCCGGGCAGAAACAACTGAAAA
TGCACTTCAGACCCACTTATTTCTGCCACATCTGAGTCGGCCTGAGATAGACTTTTCCCTCTAAACTGGGAGAATATCAC
AGTGGTTTTTGTTAGCAGAAAATGCACTCCAGCCTCTGTACTCATCTAAGCTGCTTATTTTTGATATTTGTGTCAGTCTG
TAAATGGATACTTCACTTTAATAACTGTTGCTTAGTAATTGGCTTTGTAGAGAAGCTGGAAAAAAATGGTTTTGTCTTCA
ACTCCTTTGCATGCCAGGCGGTGATGTGGATCTCGGCTTCTGTGAGCCTGTGCTGTGGGCAGGGCTGAGCTGGAGCCGCC
CCTCTCAGCCCGCCTGCCACGGCCTTTCCTTAAAGGCCATCCTTAAAACCAGACCCTCATGGCTACCAGCACCTGAAAGC
TTCCTCGACATCTGTTAATAAAGCCGTAGGCCCTTGTCTAAGTGCAACCGCCTAGACTTTCTTTCAGATACATGTCCACA
TGTCCATTTTTCAGGTTCTCTAAGTTGGAGTGGAGTCTGGGAAGGGTTGTGAATGAGGCTTCTGGGCTATGGGTGAGGTT
CCAATGGCAGGTTAGAGCCCCTCGGGCCAACTGCCATCCTGGAAAGTAGAGACAGCAGTGCCCGCTGCCCAGAAGAGACC
AGCAAGCCAAACTGGAGCCCCCATTGCAGGCTGTCGCCATGTGGAAAGAGTAACTCACAATTGCCAATAAAGTCTCATGT
GGTTTTATCTA
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Primary source |
Uniprot : O15392
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Name |
Baculoviral IAP repeat-containing protein 5
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Alternative name(s) |
Apoptosis inhibitor 4 Apoptosis inhibitor survivin
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Synonym(s) |
|
Organism |
Homo sapiens
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Length |
142 aa
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Protein existence |
---
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General annotation (Comments)
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top
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Developmental stage
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Expression is cell cycle-dependent and peaks at mitosis.
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Domain
|
The BIR repeat is necessary and sufficient for HBXIP binding.
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Function
|
Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. The complex with RAN plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. May play a role in neoplasia. May counteract a default induction of apoptosis in G2/M phase. Inhibitor of caspase-3 and caspase-7. Isoform 2 and isoform 3 do not appear to play vital roles in mitosis. Isoform 3 shows a marked reduction in its anti-apoptotic effects when compared with the displayed wild-type isoform.
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Induction
|
Up-regulated by COMP.
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Ptm
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Ubiquitination is required for centrosomal targeting.
In vitro phosphorylation at Thr-117 by AURKB/STK12 prevents interaction with INCENP and localization to mitotic chromosomes.
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Similarity
|
Belongs to the IAP family.
Contains 1 BIR repeat.
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Subcellular location
|
Cytoplasm. Nucleus. Centromere. Cytoplasm, cytoskeleton, spindle. Note=Localizes on chromosome arms and inner centromeres from prophase through metaphase and then transferring to the spindle midzone and midbody from anaphase through cytokinesis. Colocalizes with AURKB at mitotic chromosomes.
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Subunit
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Monomer or homodimer. Exist as a homodimer in the apo state and as a monomer in the CPC-bound state. When phosphorylated, interacts with HBXIP; the resulting complex binds pro-caspase-9, as well as active caspase-9, but much less efficiently. Component of the CPC at least composed of BIRC5/survivin, CDCA8/borealin, INCENP and AURKB/Aurora-B. Interacts with CDCA8 and INCENP; interaction is direct. Interacts with EVI5. Interacts with GTP-bound RAN in both the S and M phases of the cell cycle. Interacts with USP9X. Interacts with tubulin.
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Tissue specificity
|
Expressed only in fetal kidney and liver, and to lesser extent, lung and brain. Abundantly expressed in adenocarcinoma (lung, pancreas, colon, breast, and prostate) and in high-grade lymphomas. Also expressed in various renal cell carcinoma cell lines.
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Biological process
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G2/M transition of mitotic cell cycle [GO:0000086]
cytokinesis [GO:0000910]
apoptosis [GO:0006915]
anti-apoptosis [GO:0006916]
chromosome segregation [GO:0007059]
mitosis [GO:0007067]
protein complex localization [GO:0031503]
positive regulation of exit from mitosis [GO:0031536]
spindle checkpoint [GO:0031577]
negative regulation of caspase activity [GO:0043154]
positive regulation of mitotic cell cycle [GO:0045931]
cell division [GO:0051301]
establishment of chromosome localization [GO:0051303]
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Cellular component
|
nuclear chromosome [GO:0000228]
chromosome, centromeric region [GO:0000775]
cytoplasm [GO:0005737]
centriole [GO:0005814]
spindle [GO:0005819]
cytosol [GO:0005829]
spindle microtubule [GO:0005876]
cytoplasmic microtubule [GO:0005881]
midbody [GO:0030496]
interphase microtubule organizing center [GO:0031021]
chromosome passenger complex [GO:0032133]
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Molecular function
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cysteine-type endopeptidase inhibitor activity [GO:0004869]
microtubule binding [GO:0008017]
zinc ion binding [GO:0008270]
Ran GTPase binding [GO:0008536]
identical protein binding [GO:0042802]
protein homodimerization activity [GO:0042803]
caspase inhibitor activity [GO:0043027]
metal ion binding [GO:0046872]
protein heterodimerization activity [GO:0046982]
cofactor binding [GO:0048037]
cobalt ion binding [GO:0050897]
chaperone binding [GO:0051087]
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With
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Uniprot accession
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IntAct
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USF2
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Q15853
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EBI-518823,
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BIRC5
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O15392
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EBI-518823,EBI-518823
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Birc6 (xeno)
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O88738
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EBI-518823,
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CDCA8
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Q53HL2
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EBI-518823,EBI-979174
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1
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O15392-1
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EBI-518823,
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INCENP
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Q9NQS7
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EBI-518823,EBI-307907
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PPP1CC
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P36873-1
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EBI-518823,EBI-356289
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CASP9
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P55211
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EBI-518823,EBI-516799
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AURKB
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Q96GD4
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EBI-518823,EBI-624291
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CDC2
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P06493
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EBI-518823,EBI-444308
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2
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O15392-2
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EBI-518823,
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Alternative product(s)
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top
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  |
Uniprot Identifier
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Difference(s) with the 'canonical' sequence
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Notes
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Sequences
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Isoform 1
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O15392-1
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---
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'Canonical' sequence
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Get Fasta
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Isoform 2
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O15392-2
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74-74 : I -> IGPGTVAYACNTSTLGGRGGRITR
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---
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Get Fasta
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Isoform 3
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O15392-3
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74-142 : IEEHKKHSSGCAFLSVKKQFEELTLGEFLKLDRERAKNKIA KETNNKKKEFEETAEKVRRAIEQLAAMD -> MQRKPTIRR KNLRKLRRKCAVPSSSWLPWIEASGRSCLVPEWLHHFQGLF PGATSLPVGPLAMS
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---
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Get Fasta
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Isoform 4
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O15392-4
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114-142 : AKETNNKKKEFEETAEKVRRAIEQLAAMD -> ERALLAE
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---
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Get Fasta
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Isoform 5
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O15392-5
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105-142 : DRERAKNKIAKETNNKKKEFEETAEKVRRAIEQLAAMD -> VRETLPPPRSFIR
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---
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Get Fasta
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Isoform 6
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O15392-6
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74-142 : IEEHKKHSSGCAFLSVKKQFEELTLGEFLKLDRERAKNKIA KETNNKKKEFEETAEKVRRAIEQLAAMD -> MRELC
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---
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Get Fasta
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Isoform 7
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O15392-7
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74-142 : IEEHKKHSSGCAFLSVKKQFEELTLGEFLKLDRERAKNKIA KETNNKKKEFEETAEKVRRAIEQLAAMD -> M
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---
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Get Fasta
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Feature key |
Position
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Length
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Description
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Feature identifier
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Region |
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Repeat region
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18 - 88
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71
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BIR
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O15392-REPEAT-BIR
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Sites |
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Metal binding
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57 - 57
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1
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Zinc
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O15392-METAL-57
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Metal binding
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60 - 60
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1
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Zinc
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O15392-METAL-60
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Metal binding
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77 - 77
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1
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Zinc
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O15392-METAL-77
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Metal binding
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84 - 84
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1
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Zinc
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O15392-METAL-84
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Natural variations |
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Natural variant site
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129 - 129
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1
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E -> K (in dbSNP:rs2071214)
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VAR_021071
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Alternative sequence
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74 - 74
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1
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I -> IGPGTVAYACNTSTLGGRGGRITR
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VSP_002454
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Alternative sequence
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74 - 142
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69
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IEEHKKHSSGCAFLSVKKQFEELTLGEFLKLDRERAKNKIA KETNNKKKEFEETAEKVRRAIEQLAAMD -> MQRKPTIRR KNLRKLRRKCAVPSSSWLPWIEASGRSCLVPEWLHHFQGLF PGATSLPVGPLAMS
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VSP_020338
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Alternative sequence
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74 - 142
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69
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IEEHKKHSSGCAFLSVKKQFEELTLGEFLKLDRERAKNKIA KETNNKKKEFEETAEKVRRAIEQLAAMD -> M
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VSP_020340
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Alternative sequence
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74 - 142
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69
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IEEHKKHSSGCAFLSVKKQFEELTLGEFLKLDRERAKNKIA KETNNKKKEFEETAEKVRRAIEQLAAMD -> MRELC
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VSP_020339
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Alternative sequence
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105 - 142
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38
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DRERAKNKIAKETNNKKKEFEETAEKVRRAIEQLAAMD -> VRETLPPPRSFIR
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VSP_020341
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Alternative sequence
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114 - 142
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29
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AKETNNKKKEFEETAEKVRRAIEQLAAMD -> ERALLAE
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VSP_020342
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Amino acid modifications |
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Modified residue
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34 - 34
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1
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Phosphothreonine; by CDK1
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O15392-MOD_RES-34
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Modified residue
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117 - 117
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1
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Phosphothreonine; by STK12
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O15392-MOD_RES-117
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Experimental info |
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Mutagenesis
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23 - 23
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1
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K->R: Increases ubiquitination and blocks dissociation from centromeres; when associated with R-62, R-78 and R-79
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O15392-MUTAGEN-23
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Mutagenesis
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34 - 34
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1
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T->E: Higher affinity for HBXIP binding
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O15392-MUTAGEN-34
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Mutagenesis
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62 - 62
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1
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K->R: Increases ubiquitination and blocks dissociation from centromeres; when associated with R-23; R-78 and R-79
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O15392-MUTAGEN-62
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Mutagenesis
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65 - 65
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1
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E->A: Almost abolishes RAN-binding. Does not disrupt binding to AURKB or CDCA8. Disrupts mitotic spindle assembly. Does not disrupt nuclear export
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O15392-MUTAGEN-65
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Mutagenesis
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70 - 70
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1
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D->A: No change. Loss of interaction with AURKB; when associated A-71
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O15392-MUTAGEN-70
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Mutagenesis
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71 - 71
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1
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D->A: No change. Loss of interaction with AURKB; when associated with A-70
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O15392-MUTAGEN-71
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Mutagenesis
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78 - 78
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1
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K->R: Increases ubiquitination and blocks dissociation from centromeres; when associated with R-23; R-62 and R-79
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O15392-MUTAGEN-78
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Mutagenesis
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79 - 79
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1
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K->R: Increases ubiquitination and blocks dissociation from centromeres; when associated with R-23; R-62 and R-78
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O15392-MUTAGEN-79
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Mutagenesis
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84 - 84
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1
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C->A: Loss of cytoprotection
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O15392-MUTAGEN-84
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Mutagenesis
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117 - 117
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1
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T->E: Mimics phosphorylation. Disrupts subcellular localization during mitosis and prevents interaction with INCENP
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O15392-MUTAGEN-117
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1 |
MGAPTLPPAW |
QPFLKDHRIS |
TFKNWPFLEG |
CACTPERMAE |
AGFIHCPTEN |
EPDLAQCFFC |
FKELEGWEPD |
DDPIEEHKKH |
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81 |
SSGCAFLSVK |
KQFEELTLGE |
FLKLDRERAK |
NKIAKETNNK |
KKEFEETAEK |
VRRAIEQLAA |
MD |
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>sp|O15392|BIRC5_human Baculoviral IAP repeat-containing protein 5
MGAPTLPPAWQPFLKDHRISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDDDPIEEHKKH
SSGCAFLSVKKQFEELTLGEFLKLDRERAKNKIAKETNNKKKEFEETAEKVRRAIEQLAAMD
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