(SERPINA1) serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 [Homo sapiens]
Gene
Transcript(s)
Exon(s)
Protein(s)
Gene
 Accession  7264
 Official symbol  SERPINA1
 Official name  serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
 Gene type  gene with protein product
 Organism  Homo sapiens
 Location  Chromosome 14 (NC_000014.8) :  94843083...94857028  (-)
 Map  14q32.1
 Length  13946  nt
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Alternative name(s) and Synynom(s) top
Synonyms PRO2275; MGC9222; MGC23330; PI1; PI; alpha-1-antitrypsin; AAT; A1AT; A1A
Alternative name(s) serine (or cysteine) proteinase inhibitor, clade A, member 1; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1; protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin
External Links top
Ensembl ENSG00000197249
Entrez 5265
HGNC 8941
HPRD 02463
Comment top
Summary The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].
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Related Articles in PubMed
Genomic Context top
Go to ensembl   www.ensembl.org
Sequence top
FASTA
GGGCAGGAAC TGGGCACTGT GCCCAGGGCA TGCACTGCCT CCACGCAGCA ACCCTCAGAG TCCTGAGCTG AACCAAGAAG
81  GAGGAGGGGG TCGGGCCTCC GAGGAAGGCC TAGCCGCTGC TGCTGCCAGG AATTCCAGGT TGGAGGGGCG GCAACCTCCT
161  GCCAGCCTTC AGGCCACTCT CCTGTGCCTG CCAGAAGAGA CAGAGCTTGA GGAGAGCTTG AGGAGAGCAG GAAAGGTGGG
241  ACATTGCTGC TGCTGCTCAC TCAGTTCCAC AGGTGGGAGG GACAGCAGGG CTTAGAGTGG GGGTCATTGT GCAGATGGGA
321  AAACAAAGGC CCAGAGAGGG GAAGAAATGC CCAGGAGCTA CCGAGGGCAG GCGACCTCAA CCACAGCCCA GTGCTGGAGC
401  TGTGAGTGGA TGTAGAGCAG CGGAATATCC ATTCAGCCAG CTCAGGGGAA GGACAGGGGC CCTGAAGCCA GGGGATGGAG
481  CTGCAGGGAA GGGAGCTCAG AGAGAAGGGG AGGGGAGTCT GAGCTCAGTT TCCCGCTGCC TGAAAGGAGG GTGGTACCTA
561  CTCCCTTCAC AGGGTAACTG AATGAGAGAC TGCCTGGAGG AAAGCTCTTC AAGTGTGGCC CACCCCACCC CAGTGACACC
641  AGCCCCTGAC ACGGGGGAGG GAGGGCAGCA TCAGGAGGGG CTTTCTGGGC ACACCCAGTA CCCGTCTCTG AGCTTTCCTT
721  GAACTGTTGC ATTTTAATCC TCACAGCAGC TCAACAAGGT ACATACCGTC ACCATCCCCA TTTTACAGAT AGGGAAATTG
801  AGGCTCGGAG CGGTTAAACA ACTCACCTGA GGCCTCACAG CCAGTAAGTG GGTTCCCTGG TCTGAATGTG TGTGCTGGAG
881  GATCCTGTGG GTCACTCGCC TGGTAGAGCC CCAAGGTGGA GGCATAAATG GGACTGGTGA ATGACAGAAG GGGCAAAAAT
961  GCACTCATCC ATTCACTCTG CAAGTATCTA CGGCACGTAC GCCAGCTCCC AAGCAGGTTT GCGGGTTGCA CAGCGGGCGA
1041  TGCAATCTGA TTTAGGCTTT TAAAGGGATT GCAATCAAGT GGGGCCCCAC TAGCCTCAAC CCTGTACCTC CCCTCCCCTC
1121  CACCCCCAGC AGTCTCCAAA GGCCTCCAAC AACCCCAGAG TGGGGGCCAT GTATCCAAAG AAACTCCAAG CTGTATACGG
1201  ATCACACTGG TTTTCCAGGA GCAAAAACAG AAACAGGCCT GAGGCTGGTC AAAATTGAAC CTCCTCCTGC TCTGAGCAGC
1281  CTGGGGGGCA GACTAAGCAG AGGGCTGTGC AGACCCACAT AAAGAGCCTA CTGTGTGCCA GGCACTTCAC CCGAGGCACT
1361  TCACAAGCAT GCTTGGGAAT GAAACTTCCA ACTCTTTGGG ATGCAGGTGA AACAGTTCCT GGTTCAGAGA GGTGAAGCGG
1441  CCTGCCTGAG GCAGCACAGC TCTTCTTTAC AGATGTGCTT CCCCACCTCT ACCCTGTCTC ACGGCCCCCC ATGCCAGCCT
1521  GACGGTTGTG TCTGCCTCAG TCATGCTCCA TTTTTCCATC GGGACCATCA AGAGGGTGTT TGTGTCTAAG GCTGACTGGG
1601  TAACTTTGGA TGAGCGGTCT CTCCGCTCTG AGCCTGTTTC CTCATCTGTC AAATGGGCTC TAACCCACTC TGATCTCCCA
1681  GGGCGGCAGT AAGTCTTCAG CATCAGGCAT TTTGGGGTGA CTCAGTAAAT GGTAGATCTT GCTACCAGTG GAACAGCCAC
1761  TAAGGATTCT GCAGTGAGAG CAGAGGGCCA GCTAAGTGGT ACTCTCCCAG AGACTGTCTG ACTCACGCCA CCCCCTCCAC
1841  CTTGGACACA GGACGCTGTG GTTTCTGAGC CAGGTACAAT GACTCCTTTC GGTAAGTGCA GTGGAAGCTG TACACTGCCC
1921  AGGCAAAGCG TCCGGGCAGC GTAGGCGGGC GACTCAGATC CCAGCCAGTG GACTTAGCCC CTGTTTGCTC CTCCGATAAC
2001  TGGGGTGACC TTGGTTAATA TTCACCAGCA GCCTCCCCCG TTGCCCCTCT GGATCCACTG CTTAAATACG GACGAGGACA
2081  GGGCCCTGTC TCCTCAGCTT CAGGCACCAC CACTGACCTG GGACAGTGAA TCGTAAGTAT GCCTTTCACT GCGAGAGGTT
2161  CTGGAGAGGC TTCTGAGCTC CCCATGGCCC AGGCAGGCAG CAGGTCTGGG GCAGGAGGGG GGTTGTGGAG TGGGTATCCG
2241  CCTGCTGAGG TGCAGGGCAG ATGGAGAGGC TGCAGCTGAG CTCCTATTTT CATAATAACA GCAGCCATGA GGGTTGTGTC
2321  CTGTTTCCCA GTCCTGCCCG GTCCCCCCTC GGTACCTCCT GGTGGATACA CTGGTTCCTG TAAGCAGAAG TGGATGAGGG
2401  TGTCTAGGTC TGCAGTCCTG GCACCCCAGG ATGGGGGACA CCAGCCAAGA TACAGCAACA GCAACAAAGC GCAGCCATTT
2481  CTTTCTGTTT GCACAGCTCC TCTGTCTGTC GGGGGCTCCT GTCTGTTGTC TCCTATAAGC CTCACCACCT CTCCTACTGC
2561  TTGGGCATGC ATCTTTCTCC CCTTCTATAG ATGAGGAGGT TAAGGTCCAG AGAGGGGTGG GGAGGAACGC CGGCTCACAT
2641  TCTCCATCCC CTCCAGATAT GACCAGGAAC AGACCTGTGC CAGGCCTCAG CCTTACATCA AAATGGGCCT CCCCATGCAC
2721  CGTGGACCTC TGGGCCCTCC TGTCCCAGTG GAGGACAGGA AGCTGTGAGG GGCACTGTCA CCCAGGGCTC AAGCTGGCAT
2801  TCCTGAATAA TCGCTCTGCA CCAGGCCACG GCTAAGCTCA GTGCGTGATT AAGCCTCATA ACCCTCCAAG GCAGTTACTA
2881  GTGTGATTCC CATTTTACAG ATGAGGAAGA TGGGGACAGA GAGGTGAATA ACTGGCCCCA AATCACACAC CATCCATAAT
2961  TCGGGCTCAG GCACCTGGCT CCAGTCCCCA AACTCTTGAA CCTGGCCCTA GTGTCACTGT TTCTCTTGGG TCTCAGGCGC
3041  TGGATGGGGA ACAGGAAACC TGGGCTGGAC TTGAGGCCTC TCTGATGCTC GGTGACTTCA GACAGTTGCT CAACCTCTCT
3121  GTTCTCTTGG GCAAAACATG ATAACCTTTG ACTTCTGTCC CCTCCCCTCA CCCCACCCGA CCTTGATCTC TGAAGTGTTG
3201  GAAGGATTTA ATTTTTCCTG CACTGAGTTT TGGAGACAGG TCAAAAAGAT GACCAAGGCC AAGGTGGCCA GTTTCCTATA
3281  GAACGCCTCT AAAAGACCTG CAGCAATAGC AGCAAGAACT GGTATTCTCG AGAACTTGCT GCGCAGCAGG CACTTCTTGG
3361  CATTTTATGT GTATTTAATT TCACAATAGC TCTATGACAA AGTCCACCTT TCTCATCTCC AGGAAACTGA GGTTCAGAGA
3441  GGTTAAGTAA CTTGTCCAAG GTCACACAGC TAATAGCAAG TTGACGTGGA GCAATCTGGC CTCAGAGCCT TTAATTTTAG
3521  CCACAGACTG ATGCTCCCCT CTTCATTTAG CCAGGCTGCC TCTGAAGTTT TCTGATTCAA GACTTCTGGC TTCAGCTTTG
3601  TACACAGAGA TGATTCAATG TCAGGTTTTG GAGTGAAATC TGTTTAATCC CAGACAAAAC ATTTAGGATT ACATCTCAGT
3681  TTTGTAAGCA AGTAGCTCTG TGATTTTTAG TGAGTTATTT AATGCTCTTT GGGGCTCAAT TTTTCTATCT ATAAAATAGG
3761  GCTAATAATT TGCACCTTAT AGGGTAAGCT TTGAGGACAG ATTAGATGAT ACGGTGCCTG TAAAACACCA GGTGTTAGTA
3841  AGTGTGGCAA TGATGGTGAC GCTGAGGCTG ATGTTTGCTT AGCATAGGGT TAGGCAGCTG GCAGGCAGTA AACAGTTGGA
3921  TAATTTAATG GAAAATTTGC CAAACTCAGA TGCTGTTCAC TGCTGAGCAG GAGCCCCTTC CTGCTGAAAT GGTCCTGGGG
4001  AGTGCAGCAG GCTCTCCGGG AAGAAATCTA CCATCTCTCG GGCAGGAGCT CAACCTGTGT GCAGGTACAG GGAGGGCTTC
4081  CTCACCTGGT GCCCACTCAT GCATTACGTC AGTTATTCCT CATCCCTGTC CAAAGGATTC TTTTCTCCAT TGTACAGCTA
4161  TGAAGCTAGT GCTCAAAGAA GTGAAGTCAT TTACCCCAGG CCCCCTGCCA GTAAGTGACA GGGCCTGGTC ACACTTGGGT
4241  TTATTTATTG CCCAGTTCAA CAGGTTGTTT GACCATAGGC GAGATTCTCT TCCCTGCACC CTGCCGGGTT GCTCTTGGTC
4321  CCTTATTTTA TGCTCCCGGG TAGAAATGGT GTGAGATTAG GCAGGGAGTG GCTCGCTTCC CTGTCCCTGG CCCCGCAAAG
4401  AGTGCTCCCA CCTGCCCCGA TCCCAGAAAT GTCACCATGA AGCCTTCATT CTTTTGGTTT AAAGCTTGGC CTCAGTGTCC
4481  GTACACCATG GGGTACTTGG CCAGATGGCG ACTTTCTCCT CTCCAGTCGC CCTCCCAGGC ACTAGCTTTT AGGAGTGCAG
4561  GGTGCTGCCT CTGATAGAAG GGCCAGGAGA GAGCAGGTTT TGGAGTCCTG ATGTTATAAG GAACAGCTTG GGAGGCATAA
4641  TGAACCCAAC ATGATGCTTG AGACCAATGT CACAGCCCAA TTCTGACATT CATCATCTGA GATCTGAGGA CACAGCTGTC
4721  TCAGTTCATG ATCTGAGTGC TGGGAAAGCC AAGACTTGTT CCAGCTTTGT CACTGACTTG CTGTATAGCC TCAACAAGGC
4801  CCTGACCCTC TCTGGGCTTC AAACTCTTCA CTGTGAAAGG AGGAAACCAG AGTAGGTGAT GTGACACCAG GAAAGATGGA
4881  TGGGTGTGGG GGAATGTGCT CCTCCCAGCT GTCACCCCCT CGCCACCCTC CCTGCACCAG CCTCTCCACC TCCTTTGAGC
4961  CCAGAATTCC CCTGTCTAGG AGGGCACCTG TCTCATGCCT AGCCATGGGA ATTCTCCATC TGTTTTGCTA CATTGAACCC
5041  AGATGCCATT CTAACCAAGA ATCCTGGCTG GGTGCAGGGG CTCTCGCCTG TAACCCCAGC ACTTTGGGAG GCCAAGGCAG
5121  GCGGATCAAG AGGTCAGGAG TTCAAGACCT GCCTGGCCAA CACGGTGAAA CCTCAGCTCT ACTAAAAATA CAAAAATTAG
5201  CCAGGCGTGG TGGCACACGC CTGTAATCCC AGCTATTTGG GAAGCTGAGA CAGAAGAATT TCTTGAACCC GGGAGGTGGA
5281  GGTTTCAGTG AGCCGAGATC ACGCCACTGC ACTCCACCCT GGCAGATAAA GCGAGACTCT GTCTCAAAAA AAACCCAAAA
5361  ACCTATGTTA GTGTACAGAG GGCCCCAGTG AAGTCTTCTC CCAGCCCCAC TTTGCACAAC TGGGGAGAGT GAGGCCCCAG
5441  GACCAGAGGA TTCTTGCTAA AGGCCAAGTG GATAGTGATG GCCCTGCCAG GGCTAGAAGC CACAACCTCT GGCCCTGAGG
5521  CCACTCAGCA TATTTAGTGT CCCCACCCTG CAGAGGCCCA ACTCCCTCCT GACCACTGAG CCCTGTAATG ATGGGGGAAT
5601  TTCCATAAGC CATGAAGGAC TGCACAAAGT TCAGTTGGGA AGTGAAAGAG AAATTAAAGG GAGATGGAAA TATACAGCAC
5681  TAATTTTAGC ACCGTCTTTA GTTCTAACAA CACTAGCTAG CTGAAGAAAA ATACAAACAT GTATTATGTA ATGTGTGGTC
5761  TGTTCCATTT GGATTACTTA GAGGCACGAG GGCCAGGAGA AAGGTGGTGG AGAGAAACCA GCTTTGCACT TCATTTGTTG
5841  CTTTATTGGA AGGAAACTTT TAAAAGTCCA AGGGGGTTGA AGAATCTCAA TATTTGTTAT TTCCAGCTTT TTTTCTCCAG
5921  TTTTTCATTT CCCAAATTCA AGGACACCTT TTTCTTTGTA TTTTGTTAAG ATGATGGTTT TGGTTTTGTG ACTAGTAGTT
6001  AACAATGTGG CTGCCGGGCA TATTCTCCTC AGCTAGGACC TCAGTTTTCC CATCTGTGAA GACGGCAGGT TCTACCTAGG
6081  GGGCTGCAGG CTGGTGGTCC GAAGCCTGGG CATATCTGGA GTAGAAGGAT CACTGTGGGG CAGGGCAGGT TCTGTGTTGC
6161  TGTGGATGAC GTTGACTTTG ACCATTGCTC GGCAGAGCCT GCTCTCGCTG GTTCAGCCAC AGGCCCCACC ACTCCCTATT
6241  GTCTCAGCCC CGGGTATGAA ACATGTATTC CTCACTGGCC TATCACCTGA AGCCTTTGAA TTTGCAACAC CTGCCAACCC
6321  CTCCCTCAAA AGAGTTGCCC TCTCAGATCC TTTTGATGTA AGGTTTGGTG TTGAGACTTA TTTCACTAAA TTCTCATACA
6401  TAAACATCAC TTTATGTATG AGGCAAAATG AGGACCAGGG AGATGAATGA CTTGTCCTGG CTCATACACC TGGAAAGTGA
6481  CAGAGTCAGA TTAGATCCCA GGTCTATCTG AAGTTAAAAG AGGTGTCTTT TCACTTCCCA CCTCCTCCAT CTACTTTAAA
6561  GCAGCACAAA CCCCTGCTTT CAAGGAGAGA TGAGCGTCTC TAAAGCCCCT GACAGCAAGA GCCCAGAACT GGGACACCAT
6641  TAGTGACCCA GACGGCAGGT AAGCTGACTG CAGGAGCATC AGCCTATTCT TGTGTCTGGG ACCACAGAGC ATTGTGGGGA
6721  CAGCCCCGTC TCTTGGGAAA AAAACCCTAA GGGCTGAGGA TCCTTGTGAG TGTTGGGTGG GAACAGCTCC CAGGAGGTTT
6801  AATCACAGCC CCTCCATGCT CTCTAGCTGT TGCCATTGTG CAAGATGCAT TTCCCTTCTG TGCAGCAGTT TCCCTGGCCA
6881  CTAAATAGTG GGATTAGATA GAAGCCCTCC AAGGGCTTCC AGCTTGACAT GATTCTTGAT TCTGATCTGG CCCGATTCCT
6961  GGATAATCGT GGGCAGGCCC ATTCCTCTTC TTGTGCCTCA TTTTCTTCTT TTGTAAAACA ATGGCTGTAC CATTTGCATC
7041  TTAGGGTCAT TGCAGATGTA AGTGTTGCTG TCCAGAGCCT GGGTGCAGGA CCTAGATGTA GGATTCTGGT TCTGCTACTT
7121  CCTCAGTGAC ATTGAATAGC TGACCTAATC TCTCTGGCTT TGGTTTCTTC ATCTGTAAAA GAAGGATATT AGCATTAGCA
7201  CCTCACGGGA TTGTTACAAG AAAGCAATGA ATTAACACAT GTGAGCACGG AGAACAGTGC TTGGCATATG GTAAGCACTA
7281  CGTACATTTT GCTATTCTTC TGATTCTTTC AGTGTTACTG ATGTCGGCAA GTACTTGGCA CAGGCTGGTT TAATAATCCC
7361  TAGGCACTTC CACGTGGTGT CAATCCCTGA TCACTGGGAG TCATCATGTG CCTTGACTCG GGGCCTGGCC CCCCCATCTC
7441  TGTCTTGCAG GACAATGCCG TCTTCTGTCT CGTGGGGCAT CCTCCTGCTG GCAGGCCTGT GCTGCCTGGT CCCTGTCTCC
7521  CTGGCTGAGG ATCCCCAGGG AGATGCTGCC CAGAAGACAG ATACATCCCA CCATGATCAG GATCACCCAA CCTTCAACAA
7601  GATCACCCCC AACCTGGCTG AGTTCGCCTT CAGCCTATAC CGCCAGCTGG CACACCAGTC CAACAGCACC AATATCTTCT
7681  TCTCCCCAGT GAGCATCGCT ACAGCCTTTG CAATGCTCTC CCTGGGGACC AAGGCTGACA CTCACGATGA AATCCTGGAG
7761  GGCCTGAATT TCAACCTCAC GGAGATTCCG GAGGCTCAGA TCCATGAAGG CTTCCAGGAA CTCCTCCGTA CCCTCAACCA
7841  GCCAGACAGC CAGCTCCAGC TGACCACCGG CAATGGCCTG TTCCTCAGCG AGGGCCTGAA GCTAGTGGAT AAGTTTTTGG
7921  AGGATGTTAA AAAGTTGTAC CACTCAGAAG CCTTCACTGT CAACTTCGGG GACACCGAAG AGGCCAAGAA ACAGATCAAC
8001  GATTACGTGG AGAAGGGTAC TCAAGGGAAA ATTGTGGATT TGGTCAAGGA GCTTGACAGA GACACAGTTT TTGCTCTGGT
8081  GAATTACATC TTCTTTAAAG GTAAGGTTGC TCAACCAGCC TGAGCTGTTC CCATAGAAAC AAGCAAAAAT ATTCTCAAAC
8161  CATCAGTTCT TGAACTCTCC TTGGCAATGC ATTATGGGCC ATAGCAATGC TTTTCAGCGT GGATTCTTCA GTTTTCTACA
8241  CACAAACACT AAAATGTTTT CCATCATTGA GTAATTTGAG GAAATAATAG ATTAAACTGT CAAAACTACT GACAGCTCTG
8321  CAGAACTTTT CAGAGCCTTT AATGTCCTTG TGTATACTGT ATATGTAGAA TATATAATGC TTAGAACTAT AGAACAAATT
8401  GTAATACACT GCATAAAGGG ATAGTTTCAT GGAACATACT TTACACGACT CTAGTGTCCC AGAATCAGTA TCAGTTTTGC
8481  AATCTGAAAG ACCTGGGTTC AAATCCTGCC TCTAACACAA TTAGCTTTTG ACAAAAACAA TGCATTCTAC CTCTTTGAGG
8561  TGCTAATTTC TCATCTTAGC ATGGACAAAA TACCATTCTT GCTGTCAGGT TTTTTTAGGA TTAAACAAAT GACAAAGACT
8641  GTGGGGATGG TGTGTGGCAT ACAGCAGGTG ATGGACTCTT CTGTATCTCA GGCTGCCTTC CTGCCCCTGA GGGGTTAAAA
8721  TGCCAGGGTC CTGGGGGCCC CAGGGCATTC TAAGCCAGCT CCCACTGTCC CAGGAAAACA GCATAGGGGA GGGGAGGTGG
8801  GAGGCAAGGC CAGGGGCTGC TTCCTCCACT CTGAGGCTCC CTTGCTCTTG AGGCAAAGGA GGGCAGTGGA GAGCAGCCAG
8881  GCTGCAGTCA GCACAGCTAA AGTCCTGGCT CTGCTGTGGC CTTAGTGGGG GCCCAGGTCC CTCTCCAGCC CCAGTCTCCT
8961  CCTTCTGTCC AATGAGAAAG CTGGGATCAG GGGTCCCTGA GGCCCCTGTC CACTCTGCAT GCCTCGATGG TGAAGCTCTG
9041  TTGGTATGGC AGAGGGGAGG CTGCTCAGGC ATCTGCATTT CCCCTGCCAA TCTAGAGGAT GAGGAAAGCT CTCAGGAATA
9121  GTAAGCAGAA TGTTTGCCCT GGATGAATAA CTGAGCTGCC AATTAACAAG GGGCAGGGAG CCTTAGACAG AAGGTACCAA
9201  ATATGCCTGA TGCTCCAACA TTTTATTTGT AATATCCAAG ACACCCTCAA ATAAACATAT GATTCCAATA AAAATGCACA
9281  GCCACGATGG CATCTCTTAG CCTGACATCG CCACGATGTA GAAATTCTGC ATCTTCCTCT AGTTTTGAAT TATCCCCACA
9361  CAATCTTTTT CGGCAGCTTG GATGGTCAGT TTCAGCACCT TTTACAGATG ATGAAGCTGA GCCTCGAGGG ATGTGTGTCG
9441  TCAAGGGGGC TCAGGGCTTC TCAGGGAGGG GACTCATGGT TTCTTTATTC TGCTACACTC TTCCAAACCT TCACTCACCC
9521  CTGGTGATGC CCACCTTCCC CTCTCTCCAG GCAAATGGGA GAGACCCTTT GAAGTCAAGG ACACCGAGGA AGAGGACTTC
9601  CACGTGGACC AGGTGACCAC CGTGAAGGTG CCTATGATGA AGCGTTTAGG CATGTTTAAC ATCCAGCACT GTAAGAAGCT
9681  GTCCAGCTGG GTGCTGCTGA TGAAATACCT GGGCAATGCC ACCGCCATCT TCTTCCTGCC TGATGAGGGG AAACTACAGC
9761  ACCTGGAAAA TGAACTCACC CACGATATCA TCACCAAGTT CCTGGAAAAT GAAGACAGAA GGTGATTCCC CAACCTGAGG
9841  GTGACCAAGA AGCTGCCCAC ACCTCTTAGC CATGTTGGGA CTGAGGCCCA TCAGGACTGG CCAGAGGGCT GAGGAGGGTG
9921  AACCCCACAT CCCTGGGTCA CTGCTACTCT GTATAAACTT GGCTTCCAGA ATGAGGCCAC CACTGAGTTC AGGCAGCGCC
10001  ATCCATGCTC CATGAGGAGG ACAGTACCCA GGGGTGAGGA GGTAAAGGTC TCGTCCCTGG GGACTTCCCA CTCCAGTGTG
10081  GACACTGTCC CTTCCCAATA TCCAGTGCCC AGGGCAGGGA CAGCAGCACC ACCACACGTT CTGGCAGAAC CAAAAAGGAA
10161  CAGATGGGCT TCCTGGCAAA GGCAGCAGTG GAGTGTGGAG TTCAAGGGTA GAATGTCCCT GGGGGGACGG GGGAAGAGCC
10241  TGTGTGGCAA GGCCCAGAAA AGCAAGGTTC GGAATTGGAA CAGCCAGGCC ATGTTCGCAG AAGGCTTGCG TTTCTCTGTC
10321  ACTTTATCGG TGCTGTTAGA TTGGGTGTCC TGTAGTAAGT GATACTTAAA CATGAGCCAC ACATTAGTGT ATGTGTGTGC
10401  ATTCGTGATT ATGCCCATGC CCTGCTGATC TAGTTCGTTT TGTACACTGT AAAACCAAGA TGAAAATACA AAAGGTGTCG
10481  GGTTCATAAT AGGAATCGAG GCTGGAATTT CTCTGTTCCA TGCCAGCACC TCCTGAGGTC TCTGCTCCAG GGGTTGAGAA
10561  AGAACAAAGA GGCTGAGAGG GTAACGGATC AGAGAGCCCA GAGCCAAGCT GCCCGCTCAC ACCAGACCCT GCTCAGGGTG
10641  GCATTGTCTC CCCATGGAAA ACCAGAGAGG AGCACTCAGC CTGGTGTGGT CACTCTTCTC TTATCCACTA AACGGTTGTC
10721  ACTGGGCACT GCCACCAGCC CCGTGTTTCT CTGGGTGTAG GGCCCTGGGG ATGTTACAGG CTGGGGGCCA GGTGACCCAA
10801  CACTACAGGG CAAGATGAGA CAGGCTTCCA GGACACCTAG AATATCAGAG GAGGTGGCAT TTCAAGCTTT TGTGATTCAT
10881  TCGATGTTAA CATTCTTTGA CTCAATGTAG AAGAGCTAAA AGTAGAACAA ACCAAAGCCG AGTTCCCATC TTAGTGTGGG
10961  TGGAGGACAC AGGAGTAAGT GGCAGAAATA ATCAGAAAAG AAAACACTTG CACTGTGGTG GGTCCCAGAA GAACAAGAGG
11041  AATGCTGTGC CATGCCTTGA ATTTCTTTTC TGCACGACAG GTCTGCCAGC TTACATTTAC CCAAACTGTC CATTACTGGA
11121  ACCTATGATC TGAAGAGCGT CCTGGGTCAA CTGGGCATCA CTAAGGTCTT CAGCAATGGG GCTGACCTCT CCGGGGTCAC
11201  AGAGGAGGCA CCCCTGAAGC TCTCCAAGGT GAGATCACCC TGACGACCTT GTTGCACCCT GGTATCTGTA GGGAAGAATG
11281  TGTGGGGGCT GCAGCTCTGT CCTGAGGCTG AGGAAGGGGC CGAGGGAAAC AAATGAAGAC CCAGGCTGAG CTCCTGAAGA
11361  TGCCCGTGAT TCACTGACAC GGGACGTGGT CAAACAGCAA AGCCAGGCAG GGGACTGCTG TGCAGCTGGC ACTTTCGGGG
11441  CCTCCCTTGA GGTTGTGTCA CTGACCCTGA ATTTCAACTT TGCCCAAGAC CTTCTAGACA TTGGGCCTTG ATTTATCCAT
11521  ACTGACACAG AAAGGTTTGG GCTAAGTTGT TTCAAAGGAA TTTCTGACTC CTTCGATCTG TGAGATTTGG TGTCTGAATT
11601  AATGAATGAT TTCAGCTAAA GATGACACTT ATTTTGGAAA ACTAAAGGCG ACCAATGAAC AACTGCAGTT CCATGAATGG
11681  CTGCATTATC TTGGGGTCTG GGCACTGTGA AGGTCACTGC CAGGGTCCGT GTCCTCAAGG AGCTTCAAGC CGTGTACTAG
11761  AAAGGAGAGA GCCCTGGAGG CAGACGTGGA GTGACGATGC TCTTCCCTGT TCTGAGTTGT GGGTGCACCT GAGCAGGGGG
11841  AGAGGCGCTT GTCAGGAAGA TGGACAGAGG GGAGCCAGCC CCATCAGCCA AAGCCTTGAG GAGGAGCAAG GCCTATGTGA
11921  CAGGGAGGGA GAGGATGTGC AGGGCCAGGG CCGTCCAGGG GGAGTGAGCG CTTCCTGGGA GGTGTCCACG TGAGCCTTGC
12001  TCGAGGCCTG GGATCAGCCT TACAACGTGT CTCTGCTTCT CTCCCCTCCA GGCCGTGCAT AAGGCTGTGC TGACCATCGA
12081  CGAGAAAGGG ACTGAAGCTG CTGGGGCCAT GTTTTTAGAG GCCATACCCA TGTCTATCCC CCCCGAGGTC AAGTTCAACA
12161  AACCCTTTGT CTTCTTAATG ATTGAACAAA ATACCAAGTC TCCCCTCTTC ATGGGAAAAG TGGTGAATCC CACCCAAAAA
12241  TAACTGCCTC TCGCTCCTCA ACCCCTCCCC TCCATCCCTG GCCCCCTCCC TGGATGACAT TAAAGAAGGG TTGAGCTGGT
12321  CCCTGCCTGC ATGTGACTGT AAATCCCTCC CATGTTTTCT CTGAGTCTCC CTTTGCCTGC TGAGGCTGTA TGTGGGCTCC
12401  AGGTAACAGT GCTGTCTTCG GGCCCCCTGA ACTGTGTTCA TGGAGCATCT GGCTGGGTAG GCACATGCTG GGCTTGAATC
12481  CAGGGGGGAC TGAATCCTCA GCTTACGGAC CTGGGCCCAT CTGTTTCTGG AGGGCTCCAG TCTTCCTTGT CCTGTCTTGG
12561  AGTCCCCAAG AAGGAATCAC AGGGGAGGAA CCAGATACCA GCCATGACCC CAGGCTCCAC CAAGCATCTT CATGTCCCCC
12641  TGCTCATCCC CCACTCCCCC CCACCCAGAG TTGCTCATCC TGCCAGGGCT GGCTGTGCCC ACCCCAAGGC TGCCCTCCTG
12721  GGGGCCCCAG AACTGCCTGA TCGTGCCGTG GCCCAGTTTT GTGGCATCTG CAGCAACACA AGAGAGAGGA CAATGTCCTC
12801  CTCTTGACCC GCTGTCACCT AACCAGACTC GGGCCCTGCA CCTCTCAGGC ACTTCTGGAA AATGACTGAG GCAGATTCTT
12881  CCTGAAGCCC ATTCTCCATG GGGCAACAAG GACACCTATT CTGTCCTTGT CCTTCCATCG CTGCCCCAGA AAGCCTCACA
12961  TATCTCCGTT TAGAATCAGG TCCCTTCTCC CCAGATGAAG AGGAGGGTCT CTGCTTTGTT TTCTCTATCT CCTCCTCAGA
13041  CTTGACCAGG CCCAGCAGGC CCCAGAAGAC CATTACCCTA TATCCCTTCT CCTCCCTAGT CACATGGCCA TAGGCCTGCT
13121  GATGGCTCAG GAAGGCCATT GCAAGGACTC CTCAGCTATG GGAGAGGAAG CACATCACCC ATTGACCCCC GCAACCCCTC
13201  CCTTTCCTCC TCTGAGTCCC GACTGGGGCC ACATGCAGCC TGACTTCTTT GTGCCTGTTG CTGTCCCTGC AGTCTTCAGA
13281  GGGCCACCGC AGCTCCAGTG CCACGGCAGG AGGCTGTTCC TGAATAGCCC CTGTGGTAAG GGCCAGGAGA GTCCTTCCAT
13361  CCTCCAAGGC CCTGCTAAAG GACACAGCAG CCAGGAAGTC CCCTGGGCCC CTAGCTGAAG GACAGCCTGC TCCCTCCGTC
13441  TCTACCAGGA ATGGCCTTGT CCTATGGAAG GCACTGCCCC ATCCCAAACT AATCTAGGAA TCACTGTCTA ACCACTCACT
13521  GTCATGAATG TGTACTTAAA GGATGAGGTT GAGTCATACC AAATAGTGAT TTCGATAGTT CAAAATGGTG AAATTAGCAA
13601  TTCTACATGA TTCAGTCTAA TCAATGGATA CCGACTGTTT CCCACACAAG TCTCCTGTTC TCTTAAGCTT ACTCACTGAC
13681  AGCCTTTCAC TCTCCACAAA TACATTAAAG ATATGGCCAT CACCAAGCCC CCTAGGATGA CACCAGACCT GAGAGTCTGA
13761  AGACCTGGAT CCAAGTTCTG ACTTTTCCCC CTGACAGCTG TGTGACCTTC GTGAAGTCGC CAAACCTCTC TGAGCCCCAG
13841  TCATTGCTAG TAAGACCTGC CTTTGAGTTG GTATGATGTT CAAGTTAGAT AACAAAATGT TTATACCCAT TAGAACAGAG
13921  AATAAATAGA ACTACATTTC TTGCAC
>ref|Gene_ID:5265|SERPINA1|NC_000014.8:94843083...94857028 (-)
GGGCAGGAACTGGGCACTGTGCCCAGGGCATGCACTGCCTCCACGCAGCAACCCTCAGAGTCCTGAGCTGAACCAAGAAG
GAGGAGGGGGTCGGGCCTCCGAGGAAGGCCTAGCCGCTGCTGCTGCCAGGAATTCCAGGTTGGAGGGGCGGCAACCTCCT
GCCAGCCTTCAGGCCACTCTCCTGTGCCTGCCAGAAGAGACAGAGCTTGAGGAGAGCTTGAGGAGAGCAGGAAAGGTGGG
ACATTGCTGCTGCTGCTCACTCAGTTCCACAGGTGGGAGGGACAGCAGGGCTTAGAGTGGGGGTCATTGTGCAGATGGGA
AAACAAAGGCCCAGAGAGGGGAAGAAATGCCCAGGAGCTACCGAGGGCAGGCGACCTCAACCACAGCCCAGTGCTGGAGC
TGTGAGTGGATGTAGAGCAGCGGAATATCCATTCAGCCAGCTCAGGGGAAGGACAGGGGCCCTGAAGCCAGGGGATGGAG
CTGCAGGGAAGGGAGCTCAGAGAGAAGGGGAGGGGAGTCTGAGCTCAGTTTCCCGCTGCCTGAAAGGAGGGTGGTACCTA
CTCCCTTCACAGGGTAACTGAATGAGAGACTGCCTGGAGGAAAGCTCTTCAAGTGTGGCCCACCCCACCCCAGTGACACC
AGCCCCTGACACGGGGGAGGGAGGGCAGCATCAGGAGGGGCTTTCTGGGCACACCCAGTACCCGTCTCTGAGCTTTCCTT
GAACTGTTGCATTTTAATCCTCACAGCAGCTCAACAAGGTACATACCGTCACCATCCCCATTTTACAGATAGGGAAATTG
AGGCTCGGAGCGGTTAAACAACTCACCTGAGGCCTCACAGCCAGTAAGTGGGTTCCCTGGTCTGAATGTGTGTGCTGGAG
GATCCTGTGGGTCACTCGCCTGGTAGAGCCCCAAGGTGGAGGCATAAATGGGACTGGTGAATGACAGAAGGGGCAAAAAT
GCACTCATCCATTCACTCTGCAAGTATCTACGGCACGTACGCCAGCTCCCAAGCAGGTTTGCGGGTTGCACAGCGGGCGA
TGCAATCTGATTTAGGCTTTTAAAGGGATTGCAATCAAGTGGGGCCCCACTAGCCTCAACCCTGTACCTCCCCTCCCCTC
CACCCCCAGCAGTCTCCAAAGGCCTCCAACAACCCCAGAGTGGGGGCCATGTATCCAAAGAAACTCCAAGCTGTATACGG
ATCACACTGGTTTTCCAGGAGCAAAAACAGAAACAGGCCTGAGGCTGGTCAAAATTGAACCTCCTCCTGCTCTGAGCAGC
CTGGGGGGCAGACTAAGCAGAGGGCTGTGCAGACCCACATAAAGAGCCTACTGTGTGCCAGGCACTTCACCCGAGGCACT
TCACAAGCATGCTTGGGAATGAAACTTCCAACTCTTTGGGATGCAGGTGAAACAGTTCCTGGTTCAGAGAGGTGAAGCGG
CCTGCCTGAGGCAGCACAGCTCTTCTTTACAGATGTGCTTCCCCACCTCTACCCTGTCTCACGGCCCCCCATGCCAGCCT
GACGGTTGTGTCTGCCTCAGTCATGCTCCATTTTTCCATCGGGACCATCAAGAGGGTGTTTGTGTCTAAGGCTGACTGGG
TAACTTTGGATGAGCGGTCTCTCCGCTCTGAGCCTGTTTCCTCATCTGTCAAATGGGCTCTAACCCACTCTGATCTCCCA
GGGCGGCAGTAAGTCTTCAGCATCAGGCATTTTGGGGTGACTCAGTAAATGGTAGATCTTGCTACCAGTGGAACAGCCAC
TAAGGATTCTGCAGTGAGAGCAGAGGGCCAGCTAAGTGGTACTCTCCCAGAGACTGTCTGACTCACGCCACCCCCTCCAC
CTTGGACACAGGACGCTGTGGTTTCTGAGCCAGGTACAATGACTCCTTTCGGTAAGTGCAGTGGAAGCTGTACACTGCCC
AGGCAAAGCGTCCGGGCAGCGTAGGCGGGCGACTCAGATCCCAGCCAGTGGACTTAGCCCCTGTTTGCTCCTCCGATAAC
TGGGGTGACCTTGGTTAATATTCACCAGCAGCCTCCCCCGTTGCCCCTCTGGATCCACTGCTTAAATACGGACGAGGACA
GGGCCCTGTCTCCTCAGCTTCAGGCACCACCACTGACCTGGGACAGTGAATCGTAAGTATGCCTTTCACTGCGAGAGGTT
CTGGAGAGGCTTCTGAGCTCCCCATGGCCCAGGCAGGCAGCAGGTCTGGGGCAGGAGGGGGGTTGTGGAGTGGGTATCCG
CCTGCTGAGGTGCAGGGCAGATGGAGAGGCTGCAGCTGAGCTCCTATTTTCATAATAACAGCAGCCATGAGGGTTGTGTC
CTGTTTCCCAGTCCTGCCCGGTCCCCCCTCGGTACCTCCTGGTGGATACACTGGTTCCTGTAAGCAGAAGTGGATGAGGG
TGTCTAGGTCTGCAGTCCTGGCACCCCAGGATGGGGGACACCAGCCAAGATACAGCAACAGCAACAAAGCGCAGCCATTT
CTTTCTGTTTGCACAGCTCCTCTGTCTGTCGGGGGCTCCTGTCTGTTGTCTCCTATAAGCCTCACCACCTCTCCTACTGC
TTGGGCATGCATCTTTCTCCCCTTCTATAGATGAGGAGGTTAAGGTCCAGAGAGGGGTGGGGAGGAACGCCGGCTCACAT
TCTCCATCCCCTCCAGATATGACCAGGAACAGACCTGTGCCAGGCCTCAGCCTTACATCAAAATGGGCCTCCCCATGCAC
CGTGGACCTCTGGGCCCTCCTGTCCCAGTGGAGGACAGGAAGCTGTGAGGGGCACTGTCACCCAGGGCTCAAGCTGGCAT
TCCTGAATAATCGCTCTGCACCAGGCCACGGCTAAGCTCAGTGCGTGATTAAGCCTCATAACCCTCCAAGGCAGTTACTA
GTGTGATTCCCATTTTACAGATGAGGAAGATGGGGACAGAGAGGTGAATAACTGGCCCCAAATCACACACCATCCATAAT
TCGGGCTCAGGCACCTGGCTCCAGTCCCCAAACTCTTGAACCTGGCCCTAGTGTCACTGTTTCTCTTGGGTCTCAGGCGC
TGGATGGGGAACAGGAAACCTGGGCTGGACTTGAGGCCTCTCTGATGCTCGGTGACTTCAGACAGTTGCTCAACCTCTCT
GTTCTCTTGGGCAAAACATGATAACCTTTGACTTCTGTCCCCTCCCCTCACCCCACCCGACCTTGATCTCTGAAGTGTTG
GAAGGATTTAATTTTTCCTGCACTGAGTTTTGGAGACAGGTCAAAAAGATGACCAAGGCCAAGGTGGCCAGTTTCCTATA
GAACGCCTCTAAAAGACCTGCAGCAATAGCAGCAAGAACTGGTATTCTCGAGAACTTGCTGCGCAGCAGGCACTTCTTGG
CATTTTATGTGTATTTAATTTCACAATAGCTCTATGACAAAGTCCACCTTTCTCATCTCCAGGAAACTGAGGTTCAGAGA
GGTTAAGTAACTTGTCCAAGGTCACACAGCTAATAGCAAGTTGACGTGGAGCAATCTGGCCTCAGAGCCTTTAATTTTAG
CCACAGACTGATGCTCCCCTCTTCATTTAGCCAGGCTGCCTCTGAAGTTTTCTGATTCAAGACTTCTGGCTTCAGCTTTG
TACACAGAGATGATTCAATGTCAGGTTTTGGAGTGAAATCTGTTTAATCCCAGACAAAACATTTAGGATTACATCTCAGT
TTTGTAAGCAAGTAGCTCTGTGATTTTTAGTGAGTTATTTAATGCTCTTTGGGGCTCAATTTTTCTATCTATAAAATAGG
GCTAATAATTTGCACCTTATAGGGTAAGCTTTGAGGACAGATTAGATGATACGGTGCCTGTAAAACACCAGGTGTTAGTA
AGTGTGGCAATGATGGTGACGCTGAGGCTGATGTTTGCTTAGCATAGGGTTAGGCAGCTGGCAGGCAGTAAACAGTTGGA
TAATTTAATGGAAAATTTGCCAAACTCAGATGCTGTTCACTGCTGAGCAGGAGCCCCTTCCTGCTGAAATGGTCCTGGGG
AGTGCAGCAGGCTCTCCGGGAAGAAATCTACCATCTCTCGGGCAGGAGCTCAACCTGTGTGCAGGTACAGGGAGGGCTTC
CTCACCTGGTGCCCACTCATGCATTACGTCAGTTATTCCTCATCCCTGTCCAAAGGATTCTTTTCTCCATTGTACAGCTA
TGAAGCTAGTGCTCAAAGAAGTGAAGTCATTTACCCCAGGCCCCCTGCCAGTAAGTGACAGGGCCTGGTCACACTTGGGT
TTATTTATTGCCCAGTTCAACAGGTTGTTTGACCATAGGCGAGATTCTCTTCCCTGCACCCTGCCGGGTTGCTCTTGGTC
CCTTATTTTATGCTCCCGGGTAGAAATGGTGTGAGATTAGGCAGGGAGTGGCTCGCTTCCCTGTCCCTGGCCCCGCAAAG
AGTGCTCCCACCTGCCCCGATCCCAGAAATGTCACCATGAAGCCTTCATTCTTTTGGTTTAAAGCTTGGCCTCAGTGTCC
GTACACCATGGGGTACTTGGCCAGATGGCGACTTTCTCCTCTCCAGTCGCCCTCCCAGGCACTAGCTTTTAGGAGTGCAG
GGTGCTGCCTCTGATAGAAGGGCCAGGAGAGAGCAGGTTTTGGAGTCCTGATGTTATAAGGAACAGCTTGGGAGGCATAA
TGAACCCAACATGATGCTTGAGACCAATGTCACAGCCCAATTCTGACATTCATCATCTGAGATCTGAGGACACAGCTGTC
TCAGTTCATGATCTGAGTGCTGGGAAAGCCAAGACTTGTTCCAGCTTTGTCACTGACTTGCTGTATAGCCTCAACAAGGC
CCTGACCCTCTCTGGGCTTCAAACTCTTCACTGTGAAAGGAGGAAACCAGAGTAGGTGATGTGACACCAGGAAAGATGGA
TGGGTGTGGGGGAATGTGCTCCTCCCAGCTGTCACCCCCTCGCCACCCTCCCTGCACCAGCCTCTCCACCTCCTTTGAGC
CCAGAATTCCCCTGTCTAGGAGGGCACCTGTCTCATGCCTAGCCATGGGAATTCTCCATCTGTTTTGCTACATTGAACCC
AGATGCCATTCTAACCAAGAATCCTGGCTGGGTGCAGGGGCTCTCGCCTGTAACCCCAGCACTTTGGGAGGCCAAGGCAG
GCGGATCAAGAGGTCAGGAGTTCAAGACCTGCCTGGCCAACACGGTGAAACCTCAGCTCTACTAAAAATACAAAAATTAG
CCAGGCGTGGTGGCACACGCCTGTAATCCCAGCTATTTGGGAAGCTGAGACAGAAGAATTTCTTGAACCCGGGAGGTGGA
GGTTTCAGTGAGCCGAGATCACGCCACTGCACTCCACCCTGGCAGATAAAGCGAGACTCTGTCTCAAAAAAAACCCAAAA
ACCTATGTTAGTGTACAGAGGGCCCCAGTGAAGTCTTCTCCCAGCCCCACTTTGCACAACTGGGGAGAGTGAGGCCCCAG
GACCAGAGGATTCTTGCTAAAGGCCAAGTGGATAGTGATGGCCCTGCCAGGGCTAGAAGCCACAACCTCTGGCCCTGAGG
CCACTCAGCATATTTAGTGTCCCCACCCTGCAGAGGCCCAACTCCCTCCTGACCACTGAGCCCTGTAATGATGGGGGAAT
TTCCATAAGCCATGAAGGACTGCACAAAGTTCAGTTGGGAAGTGAAAGAGAAATTAAAGGGAGATGGAAATATACAGCAC
TAATTTTAGCACCGTCTTTAGTTCTAACAACACTAGCTAGCTGAAGAAAAATACAAACATGTATTATGTAATGTGTGGTC
TGTTCCATTTGGATTACTTAGAGGCACGAGGGCCAGGAGAAAGGTGGTGGAGAGAAACCAGCTTTGCACTTCATTTGTTG
CTTTATTGGAAGGAAACTTTTAAAAGTCCAAGGGGGTTGAAGAATCTCAATATTTGTTATTTCCAGCTTTTTTTCTCCAG
TTTTTCATTTCCCAAATTCAAGGACACCTTTTTCTTTGTATTTTGTTAAGATGATGGTTTTGGTTTTGTGACTAGTAGTT
AACAATGTGGCTGCCGGGCATATTCTCCTCAGCTAGGACCTCAGTTTTCCCATCTGTGAAGACGGCAGGTTCTACCTAGG
GGGCTGCAGGCTGGTGGTCCGAAGCCTGGGCATATCTGGAGTAGAAGGATCACTGTGGGGCAGGGCAGGTTCTGTGTTGC
TGTGGATGACGTTGACTTTGACCATTGCTCGGCAGAGCCTGCTCTCGCTGGTTCAGCCACAGGCCCCACCACTCCCTATT
GTCTCAGCCCCGGGTATGAAACATGTATTCCTCACTGGCCTATCACCTGAAGCCTTTGAATTTGCAACACCTGCCAACCC
CTCCCTCAAAAGAGTTGCCCTCTCAGATCCTTTTGATGTAAGGTTTGGTGTTGAGACTTATTTCACTAAATTCTCATACA
TAAACATCACTTTATGTATGAGGCAAAATGAGGACCAGGGAGATGAATGACTTGTCCTGGCTCATACACCTGGAAAGTGA
CAGAGTCAGATTAGATCCCAGGTCTATCTGAAGTTAAAAGAGGTGTCTTTTCACTTCCCACCTCCTCCATCTACTTTAAA
GCAGCACAAACCCCTGCTTTCAAGGAGAGATGAGCGTCTCTAAAGCCCCTGACAGCAAGAGCCCAGAACTGGGACACCAT
TAGTGACCCAGACGGCAGGTAAGCTGACTGCAGGAGCATCAGCCTATTCTTGTGTCTGGGACCACAGAGCATTGTGGGGA
CAGCCCCGTCTCTTGGGAAAAAAACCCTAAGGGCTGAGGATCCTTGTGAGTGTTGGGTGGGAACAGCTCCCAGGAGGTTT
AATCACAGCCCCTCCATGCTCTCTAGCTGTTGCCATTGTGCAAGATGCATTTCCCTTCTGTGCAGCAGTTTCCCTGGCCA
CTAAATAGTGGGATTAGATAGAAGCCCTCCAAGGGCTTCCAGCTTGACATGATTCTTGATTCTGATCTGGCCCGATTCCT
GGATAATCGTGGGCAGGCCCATTCCTCTTCTTGTGCCTCATTTTCTTCTTTTGTAAAACAATGGCTGTACCATTTGCATC
TTAGGGTCATTGCAGATGTAAGTGTTGCTGTCCAGAGCCTGGGTGCAGGACCTAGATGTAGGATTCTGGTTCTGCTACTT
CCTCAGTGACATTGAATAGCTGACCTAATCTCTCTGGCTTTGGTTTCTTCATCTGTAAAAGAAGGATATTAGCATTAGCA
CCTCACGGGATTGTTACAAGAAAGCAATGAATTAACACATGTGAGCACGGAGAACAGTGCTTGGCATATGGTAAGCACTA
CGTACATTTTGCTATTCTTCTGATTCTTTCAGTGTTACTGATGTCGGCAAGTACTTGGCACAGGCTGGTTTAATAATCCC
TAGGCACTTCCACGTGGTGTCAATCCCTGATCACTGGGAGTCATCATGTGCCTTGACTCGGGGCCTGGCCCCCCCATCTC
TGTCTTGCAGGACAATGCCGTCTTCTGTCTCGTGGGGCATCCTCCTGCTGGCAGGCCTGTGCTGCCTGGTCCCTGTCTCC
CTGGCTGAGGATCCCCAGGGAGATGCTGCCCAGAAGACAGATACATCCCACCATGATCAGGATCACCCAACCTTCAACAA
GATCACCCCCAACCTGGCTGAGTTCGCCTTCAGCCTATACCGCCAGCTGGCACACCAGTCCAACAGCACCAATATCTTCT
TCTCCCCAGTGAGCATCGCTACAGCCTTTGCAATGCTCTCCCTGGGGACCAAGGCTGACACTCACGATGAAATCCTGGAG
GGCCTGAATTTCAACCTCACGGAGATTCCGGAGGCTCAGATCCATGAAGGCTTCCAGGAACTCCTCCGTACCCTCAACCA
GCCAGACAGCCAGCTCCAGCTGACCACCGGCAATGGCCTGTTCCTCAGCGAGGGCCTGAAGCTAGTGGATAAGTTTTTGG
AGGATGTTAAAAAGTTGTACCACTCAGAAGCCTTCACTGTCAACTTCGGGGACACCGAAGAGGCCAAGAAACAGATCAAC
GATTACGTGGAGAAGGGTACTCAAGGGAAAATTGTGGATTTGGTCAAGGAGCTTGACAGAGACACAGTTTTTGCTCTGGT
GAATTACATCTTCTTTAAAGGTAAGGTTGCTCAACCAGCCTGAGCTGTTCCCATAGAAACAAGCAAAAATATTCTCAAAC
CATCAGTTCTTGAACTCTCCTTGGCAATGCATTATGGGCCATAGCAATGCTTTTCAGCGTGGATTCTTCAGTTTTCTACA
CACAAACACTAAAATGTTTTCCATCATTGAGTAATTTGAGGAAATAATAGATTAAACTGTCAAAACTACTGACAGCTCTG
CAGAACTTTTCAGAGCCTTTAATGTCCTTGTGTATACTGTATATGTAGAATATATAATGCTTAGAACTATAGAACAAATT
GTAATACACTGCATAAAGGGATAGTTTCATGGAACATACTTTACACGACTCTAGTGTCCCAGAATCAGTATCAGTTTTGC
AATCTGAAAGACCTGGGTTCAAATCCTGCCTCTAACACAATTAGCTTTTGACAAAAACAATGCATTCTACCTCTTTGAGG
TGCTAATTTCTCATCTTAGCATGGACAAAATACCATTCTTGCTGTCAGGTTTTTTTAGGATTAAACAAATGACAAAGACT
GTGGGGATGGTGTGTGGCATACAGCAGGTGATGGACTCTTCTGTATCTCAGGCTGCCTTCCTGCCCCTGAGGGGTTAAAA
TGCCAGGGTCCTGGGGGCCCCAGGGCATTCTAAGCCAGCTCCCACTGTCCCAGGAAAACAGCATAGGGGAGGGGAGGTGG
GAGGCAAGGCCAGGGGCTGCTTCCTCCACTCTGAGGCTCCCTTGCTCTTGAGGCAAAGGAGGGCAGTGGAGAGCAGCCAG
GCTGCAGTCAGCACAGCTAAAGTCCTGGCTCTGCTGTGGCCTTAGTGGGGGCCCAGGTCCCTCTCCAGCCCCAGTCTCCT
CCTTCTGTCCAATGAGAAAGCTGGGATCAGGGGTCCCTGAGGCCCCTGTCCACTCTGCATGCCTCGATGGTGAAGCTCTG
TTGGTATGGCAGAGGGGAGGCTGCTCAGGCATCTGCATTTCCCCTGCCAATCTAGAGGATGAGGAAAGCTCTCAGGAATA
GTAAGCAGAATGTTTGCCCTGGATGAATAACTGAGCTGCCAATTAACAAGGGGCAGGGAGCCTTAGACAGAAGGTACCAA
ATATGCCTGATGCTCCAACATTTTATTTGTAATATCCAAGACACCCTCAAATAAACATATGATTCCAATAAAAATGCACA
GCCACGATGGCATCTCTTAGCCTGACATCGCCACGATGTAGAAATTCTGCATCTTCCTCTAGTTTTGAATTATCCCCACA
CAATCTTTTTCGGCAGCTTGGATGGTCAGTTTCAGCACCTTTTACAGATGATGAAGCTGAGCCTCGAGGGATGTGTGTCG
TCAAGGGGGCTCAGGGCTTCTCAGGGAGGGGACTCATGGTTTCTTTATTCTGCTACACTCTTCCAAACCTTCACTCACCC
CTGGTGATGCCCACCTTCCCCTCTCTCCAGGCAAATGGGAGAGACCCTTTGAAGTCAAGGACACCGAGGAAGAGGACTTC
CACGTGGACCAGGTGACCACCGTGAAGGTGCCTATGATGAAGCGTTTAGGCATGTTTAACATCCAGCACTGTAAGAAGCT
GTCCAGCTGGGTGCTGCTGATGAAATACCTGGGCAATGCCACCGCCATCTTCTTCCTGCCTGATGAGGGGAAACTACAGC
ACCTGGAAAATGAACTCACCCACGATATCATCACCAAGTTCCTGGAAAATGAAGACAGAAGGTGATTCCCCAACCTGAGG
GTGACCAAGAAGCTGCCCACACCTCTTAGCCATGTTGGGACTGAGGCCCATCAGGACTGGCCAGAGGGCTGAGGAGGGTG
AACCCCACATCCCTGGGTCACTGCTACTCTGTATAAACTTGGCTTCCAGAATGAGGCCACCACTGAGTTCAGGCAGCGCC
ATCCATGCTCCATGAGGAGGACAGTACCCAGGGGTGAGGAGGTAAAGGTCTCGTCCCTGGGGACTTCCCACTCCAGTGTG
GACACTGTCCCTTCCCAATATCCAGTGCCCAGGGCAGGGACAGCAGCACCACCACACGTTCTGGCAGAACCAAAAAGGAA
CAGATGGGCTTCCTGGCAAAGGCAGCAGTGGAGTGTGGAGTTCAAGGGTAGAATGTCCCTGGGGGGACGGGGGAAGAGCC
TGTGTGGCAAGGCCCAGAAAAGCAAGGTTCGGAATTGGAACAGCCAGGCCATGTTCGCAGAAGGCTTGCGTTTCTCTGTC
ACTTTATCGGTGCTGTTAGATTGGGTGTCCTGTAGTAAGTGATACTTAAACATGAGCCACACATTAGTGTATGTGTGTGC
ATTCGTGATTATGCCCATGCCCTGCTGATCTAGTTCGTTTTGTACACTGTAAAACCAAGATGAAAATACAAAAGGTGTCG
GGTTCATAATAGGAATCGAGGCTGGAATTTCTCTGTTCCATGCCAGCACCTCCTGAGGTCTCTGCTCCAGGGGTTGAGAA
AGAACAAAGAGGCTGAGAGGGTAACGGATCAGAGAGCCCAGAGCCAAGCTGCCCGCTCACACCAGACCCTGCTCAGGGTG
GCATTGTCTCCCCATGGAAAACCAGAGAGGAGCACTCAGCCTGGTGTGGTCACTCTTCTCTTATCCACTAAACGGTTGTC
ACTGGGCACTGCCACCAGCCCCGTGTTTCTCTGGGTGTAGGGCCCTGGGGATGTTACAGGCTGGGGGCCAGGTGACCCAA
CACTACAGGGCAAGATGAGACAGGCTTCCAGGACACCTAGAATATCAGAGGAGGTGGCATTTCAAGCTTTTGTGATTCAT
TCGATGTTAACATTCTTTGACTCAATGTAGAAGAGCTAAAAGTAGAACAAACCAAAGCCGAGTTCCCATCTTAGTGTGGG
TGGAGGACACAGGAGTAAGTGGCAGAAATAATCAGAAAAGAAAACACTTGCACTGTGGTGGGTCCCAGAAGAACAAGAGG
AATGCTGTGCCATGCCTTGAATTTCTTTTCTGCACGACAGGTCTGCCAGCTTACATTTACCCAAACTGTCCATTACTGGA
ACCTATGATCTGAAGAGCGTCCTGGGTCAACTGGGCATCACTAAGGTCTTCAGCAATGGGGCTGACCTCTCCGGGGTCAC
AGAGGAGGCACCCCTGAAGCTCTCCAAGGTGAGATCACCCTGACGACCTTGTTGCACCCTGGTATCTGTAGGGAAGAATG
TGTGGGGGCTGCAGCTCTGTCCTGAGGCTGAGGAAGGGGCCGAGGGAAACAAATGAAGACCCAGGCTGAGCTCCTGAAGA
TGCCCGTGATTCACTGACACGGGACGTGGTCAAACAGCAAAGCCAGGCAGGGGACTGCTGTGCAGCTGGCACTTTCGGGG
CCTCCCTTGAGGTTGTGTCACTGACCCTGAATTTCAACTTTGCCCAAGACCTTCTAGACATTGGGCCTTGATTTATCCAT
ACTGACACAGAAAGGTTTGGGCTAAGTTGTTTCAAAGGAATTTCTGACTCCTTCGATCTGTGAGATTTGGTGTCTGAATT
AATGAATGATTTCAGCTAAAGATGACACTTATTTTGGAAAACTAAAGGCGACCAATGAACAACTGCAGTTCCATGAATGG
CTGCATTATCTTGGGGTCTGGGCACTGTGAAGGTCACTGCCAGGGTCCGTGTCCTCAAGGAGCTTCAAGCCGTGTACTAG
AAAGGAGAGAGCCCTGGAGGCAGACGTGGAGTGACGATGCTCTTCCCTGTTCTGAGTTGTGGGTGCACCTGAGCAGGGGG
AGAGGCGCTTGTCAGGAAGATGGACAGAGGGGAGCCAGCCCCATCAGCCAAAGCCTTGAGGAGGAGCAAGGCCTATGTGA
CAGGGAGGGAGAGGATGTGCAGGGCCAGGGCCGTCCAGGGGGAGTGAGCGCTTCCTGGGAGGTGTCCACGTGAGCCTTGC
TCGAGGCCTGGGATCAGCCTTACAACGTGTCTCTGCTTCTCTCCCCTCCAGGCCGTGCATAAGGCTGTGCTGACCATCGA
CGAGAAAGGGACTGAAGCTGCTGGGGCCATGTTTTTAGAGGCCATACCCATGTCTATCCCCCCCGAGGTCAAGTTCAACA
AACCCTTTGTCTTCTTAATGATTGAACAAAATACCAAGTCTCCCCTCTTCATGGGAAAAGTGGTGAATCCCACCCAAAAA
TAACTGCCTCTCGCTCCTCAACCCCTCCCCTCCATCCCTGGCCCCCTCCCTGGATGACATTAAAGAAGGGTTGAGCTGGT
CCCTGCCTGCATGTGACTGTAAATCCCTCCCATGTTTTCTCTGAGTCTCCCTTTGCCTGCTGAGGCTGTATGTGGGCTCC
AGGTAACAGTGCTGTCTTCGGGCCCCCTGAACTGTGTTCATGGAGCATCTGGCTGGGTAGGCACATGCTGGGCTTGAATC
CAGGGGGGACTGAATCCTCAGCTTACGGACCTGGGCCCATCTGTTTCTGGAGGGCTCCAGTCTTCCTTGTCCTGTCTTGG
AGTCCCCAAGAAGGAATCACAGGGGAGGAACCAGATACCAGCCATGACCCCAGGCTCCACCAAGCATCTTCATGTCCCCC
TGCTCATCCCCCACTCCCCCCCACCCAGAGTTGCTCATCCTGCCAGGGCTGGCTGTGCCCACCCCAAGGCTGCCCTCCTG
GGGGCCCCAGAACTGCCTGATCGTGCCGTGGCCCAGTTTTGTGGCATCTGCAGCAACACAAGAGAGAGGACAATGTCCTC
CTCTTGACCCGCTGTCACCTAACCAGACTCGGGCCCTGCACCTCTCAGGCACTTCTGGAAAATGACTGAGGCAGATTCTT
CCTGAAGCCCATTCTCCATGGGGCAACAAGGACACCTATTCTGTCCTTGTCCTTCCATCGCTGCCCCAGAAAGCCTCACA
TATCTCCGTTTAGAATCAGGTCCCTTCTCCCCAGATGAAGAGGAGGGTCTCTGCTTTGTTTTCTCTATCTCCTCCTCAGA
CTTGACCAGGCCCAGCAGGCCCCAGAAGACCATTACCCTATATCCCTTCTCCTCCCTAGTCACATGGCCATAGGCCTGCT
GATGGCTCAGGAAGGCCATTGCAAGGACTCCTCAGCTATGGGAGAGGAAGCACATCACCCATTGACCCCCGCAACCCCTC
CCTTTCCTCCTCTGAGTCCCGACTGGGGCCACATGCAGCCTGACTTCTTTGTGCCTGTTGCTGTCCCTGCAGTCTTCAGA
GGGCCACCGCAGCTCCAGTGCCACGGCAGGAGGCTGTTCCTGAATAGCCCCTGTGGTAAGGGCCAGGAGAGTCCTTCCAT
CCTCCAAGGCCCTGCTAAAGGACACAGCAGCCAGGAAGTCCCCTGGGCCCCTAGCTGAAGGACAGCCTGCTCCCTCCGTC
TCTACCAGGAATGGCCTTGTCCTATGGAAGGCACTGCCCCATCCCAAACTAATCTAGGAATCACTGTCTAACCACTCACT
GTCATGAATGTGTACTTAAAGGATGAGGTTGAGTCATACCAAATAGTGATTTCGATAGTTCAAAATGGTGAAATTAGCAA
TTCTACATGATTCAGTCTAATCAATGGATACCGACTGTTTCCCACACAAGTCTCCTGTTCTCTTAAGCTTACTCACTGAC
AGCCTTTCACTCTCCACAAATACATTAAAGATATGGCCATCACCAAGCCCCCTAGGATGACACCAGACCTGAGAGTCTGA
AGACCTGGATCCAAGTTCTGACTTTTCCCCCTGACAGCTGTGTGACCTTCGTGAAGTCGCCAAACCTCTCTGAGCCCCAG
TCATTGCTAGTAAGACCTGCCTTTGAGTTGGTATGATGTTCAAGTTAGATAACAAAATGTTTATACCCATTAGAACAGAG
AATAAATAGAACTACATTTCTTGCAC