(SERPINA1) serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 [Homo sapiens] |
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Gene
Transcript(s)
Exon(s)
Protein(s)
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Accession
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7264
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Official symbol
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SERPINA1
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Official name
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serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
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Gene type
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gene with protein product
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Organism
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Homo sapiens
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Location
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Chromosome 14 (NC_000014.8) : 94843083...94857028 (-)
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Map
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14q32.1
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Length
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13946 nt
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NM_000295.4
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SERPINA1, mRNA isoform 1
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NM_001127706.1
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SERPINA1, mRNA isoform 10
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NM_001127707.1
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SERPINA1, mRNA isoform 11
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NM_001002236.2
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SERPINA1, mRNA isoform 2
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NM_001002235.2
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SERPINA1, mRNA isoform 3
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NM_001127700.1
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SERPINA1, mRNA isoform 4
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NM_001127701.1
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SERPINA1, mRNA isoform 5
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NM_001127702.1
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SERPINA1, mRNA isoform 6
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NM_001127703.1
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SERPINA1, mRNA isoform 7
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NM_001127704.1
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SERPINA1, mRNA isoform 8
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NM_001127705.1
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SERPINA1, mRNA isoform 9
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Accession
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Name
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Organism
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Length
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P01009
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Alpha-1-antitrypsin
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Homo sapiens
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418 aa
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Synonyms |
PRO2275; MGC9222; MGC23330; PI1; PI; alpha-1-antitrypsin; AAT; A1AT; A1A
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Alternative name(s) |
serine (or cysteine) proteinase inhibitor, clade A, member 1; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1; protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin
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Summary |
The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].
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Related Articles in PubMed
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Go to ensembl
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1 |
GGGCAGGAAC |
TGGGCACTGT |
GCCCAGGGCA |
TGCACTGCCT |
CCACGCAGCA |
ACCCTCAGAG |
TCCTGAGCTG |
AACCAAGAAG |
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81 |
GAGGAGGGGG |
TCGGGCCTCC |
GAGGAAGGCC |
TAGCCGCTGC |
TGCTGCCAGG |
AATTCCAGGT |
TGGAGGGGCG |
GCAACCTCCT |
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161 |
GCCAGCCTTC |
AGGCCACTCT |
CCTGTGCCTG |
CCAGAAGAGA |
CAGAGCTTGA |
GGAGAGCTTG |
AGGAGAGCAG |
GAAAGGTGGG |
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241 |
ACATTGCTGC |
TGCTGCTCAC |
TCAGTTCCAC |
AGGTGGGAGG |
GACAGCAGGG |
CTTAGAGTGG |
GGGTCATTGT |
GCAGATGGGA |
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321 |
AAACAAAGGC |
CCAGAGAGGG |
GAAGAAATGC |
CCAGGAGCTA |
CCGAGGGCAG |
GCGACCTCAA |
CCACAGCCCA |
GTGCTGGAGC |
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401 |
TGTGAGTGGA |
TGTAGAGCAG |
CGGAATATCC |
ATTCAGCCAG |
CTCAGGGGAA |
GGACAGGGGC |
CCTGAAGCCA |
GGGGATGGAG |
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481 |
CTGCAGGGAA |
GGGAGCTCAG |
AGAGAAGGGG |
AGGGGAGTCT |
GAGCTCAGTT |
TCCCGCTGCC |
TGAAAGGAGG |
GTGGTACCTA |
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561 |
CTCCCTTCAC |
AGGGTAACTG |
AATGAGAGAC |
TGCCTGGAGG |
AAAGCTCTTC |
AAGTGTGGCC |
CACCCCACCC |
CAGTGACACC |
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641 |
AGCCCCTGAC |
ACGGGGGAGG |
GAGGGCAGCA |
TCAGGAGGGG |
CTTTCTGGGC |
ACACCCAGTA |
CCCGTCTCTG |
AGCTTTCCTT |
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721 |
GAACTGTTGC |
ATTTTAATCC |
TCACAGCAGC |
TCAACAAGGT |
ACATACCGTC |
ACCATCCCCA |
TTTTACAGAT |
AGGGAAATTG |
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801 |
AGGCTCGGAG |
CGGTTAAACA |
ACTCACCTGA |
GGCCTCACAG |
CCAGTAAGTG |
GGTTCCCTGG |
TCTGAATGTG |
TGTGCTGGAG |
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881 |
GATCCTGTGG |
GTCACTCGCC |
TGGTAGAGCC |
CCAAGGTGGA |
GGCATAAATG |
GGACTGGTGA |
ATGACAGAAG |
GGGCAAAAAT |
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961 |
GCACTCATCC |
ATTCACTCTG |
CAAGTATCTA |
CGGCACGTAC |
GCCAGCTCCC |
AAGCAGGTTT |
GCGGGTTGCA |
CAGCGGGCGA |
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1041 |
TGCAATCTGA |
TTTAGGCTTT |
TAAAGGGATT |
GCAATCAAGT |
GGGGCCCCAC |
TAGCCTCAAC |
CCTGTACCTC |
CCCTCCCCTC |
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1121 |
CACCCCCAGC |
AGTCTCCAAA |
GGCCTCCAAC |
AACCCCAGAG |
TGGGGGCCAT |
GTATCCAAAG |
AAACTCCAAG |
CTGTATACGG |
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1201 |
ATCACACTGG |
TTTTCCAGGA |
GCAAAAACAG |
AAACAGGCCT |
GAGGCTGGTC |
AAAATTGAAC |
CTCCTCCTGC |
TCTGAGCAGC |
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1281 |
CTGGGGGGCA |
GACTAAGCAG |
AGGGCTGTGC |
AGACCCACAT |
AAAGAGCCTA |
CTGTGTGCCA |
GGCACTTCAC |
CCGAGGCACT |
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1361 |
TCACAAGCAT |
GCTTGGGAAT |
GAAACTTCCA |
ACTCTTTGGG |
ATGCAGGTGA |
AACAGTTCCT |
GGTTCAGAGA |
GGTGAAGCGG |
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1441 |
CCTGCCTGAG |
GCAGCACAGC |
TCTTCTTTAC |
AGATGTGCTT |
CCCCACCTCT |
ACCCTGTCTC |
ACGGCCCCCC |
ATGCCAGCCT |
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1521 |
GACGGTTGTG |
TCTGCCTCAG |
TCATGCTCCA |
TTTTTCCATC |
GGGACCATCA |
AGAGGGTGTT |
TGTGTCTAAG |
GCTGACTGGG |
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1601 |
TAACTTTGGA |
TGAGCGGTCT |
CTCCGCTCTG |
AGCCTGTTTC |
CTCATCTGTC |
AAATGGGCTC |
TAACCCACTC |
TGATCTCCCA |
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1681 |
GGGCGGCAGT |
AAGTCTTCAG |
CATCAGGCAT |
TTTGGGGTGA |
CTCAGTAAAT |
GGTAGATCTT |
GCTACCAGTG |
GAACAGCCAC |
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1761 |
TAAGGATTCT |
GCAGTGAGAG |
CAGAGGGCCA |
GCTAAGTGGT |
ACTCTCCCAG |
AGACTGTCTG |
ACTCACGCCA |
CCCCCTCCAC |
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1841 |
CTTGGACACA |
GGACGCTGTG |
GTTTCTGAGC |
CAGGTACAAT |
GACTCCTTTC |
GGTAAGTGCA |
GTGGAAGCTG |
TACACTGCCC |
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1921 |
AGGCAAAGCG |
TCCGGGCAGC |
GTAGGCGGGC |
GACTCAGATC |
CCAGCCAGTG |
GACTTAGCCC |
CTGTTTGCTC |
CTCCGATAAC |
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2001 |
TGGGGTGACC |
TTGGTTAATA |
TTCACCAGCA |
GCCTCCCCCG |
TTGCCCCTCT |
GGATCCACTG |
CTTAAATACG |
GACGAGGACA |
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2081 |
GGGCCCTGTC |
TCCTCAGCTT |
CAGGCACCAC |
CACTGACCTG |
GGACAGTGAA |
TCGTAAGTAT |
GCCTTTCACT |
GCGAGAGGTT |
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2161 |
CTGGAGAGGC |
TTCTGAGCTC |
CCCATGGCCC |
AGGCAGGCAG |
CAGGTCTGGG |
GCAGGAGGGG |
GGTTGTGGAG |
TGGGTATCCG |
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2241 |
CCTGCTGAGG |
TGCAGGGCAG |
ATGGAGAGGC |
TGCAGCTGAG |
CTCCTATTTT |
CATAATAACA |
GCAGCCATGA |
GGGTTGTGTC |
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2321 |
CTGTTTCCCA |
GTCCTGCCCG |
GTCCCCCCTC |
GGTACCTCCT |
GGTGGATACA |
CTGGTTCCTG |
TAAGCAGAAG |
TGGATGAGGG |
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2401 |
TGTCTAGGTC |
TGCAGTCCTG |
GCACCCCAGG |
ATGGGGGACA |
CCAGCCAAGA |
TACAGCAACA |
GCAACAAAGC |
GCAGCCATTT |
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2481 |
CTTTCTGTTT |
GCACAGCTCC |
TCTGTCTGTC |
GGGGGCTCCT |
GTCTGTTGTC |
TCCTATAAGC |
CTCACCACCT |
CTCCTACTGC |
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2561 |
TTGGGCATGC |
ATCTTTCTCC |
CCTTCTATAG |
ATGAGGAGGT |
TAAGGTCCAG |
AGAGGGGTGG |
GGAGGAACGC |
CGGCTCACAT |
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2641 |
TCTCCATCCC |
CTCCAGATAT |
GACCAGGAAC |
AGACCTGTGC |
CAGGCCTCAG |
CCTTACATCA |
AAATGGGCCT |
CCCCATGCAC |
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2721 |
CGTGGACCTC |
TGGGCCCTCC |
TGTCCCAGTG |
GAGGACAGGA |
AGCTGTGAGG |
GGCACTGTCA |
CCCAGGGCTC |
AAGCTGGCAT |
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2801 |
TCCTGAATAA |
TCGCTCTGCA |
CCAGGCCACG |
GCTAAGCTCA |
GTGCGTGATT |
AAGCCTCATA |
ACCCTCCAAG |
GCAGTTACTA |
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2881 |
GTGTGATTCC |
CATTTTACAG |
ATGAGGAAGA |
TGGGGACAGA |
GAGGTGAATA |
ACTGGCCCCA |
AATCACACAC |
CATCCATAAT |
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2961 |
TCGGGCTCAG |
GCACCTGGCT |
CCAGTCCCCA |
AACTCTTGAA |
CCTGGCCCTA |
GTGTCACTGT |
TTCTCTTGGG |
TCTCAGGCGC |
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3041 |
TGGATGGGGA |
ACAGGAAACC |
TGGGCTGGAC |
TTGAGGCCTC |
TCTGATGCTC |
GGTGACTTCA |
GACAGTTGCT |
CAACCTCTCT |
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3121 |
GTTCTCTTGG |
GCAAAACATG |
ATAACCTTTG |
ACTTCTGTCC |
CCTCCCCTCA |
CCCCACCCGA |
CCTTGATCTC |
TGAAGTGTTG |
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3201 |
GAAGGATTTA |
ATTTTTCCTG |
CACTGAGTTT |
TGGAGACAGG |
TCAAAAAGAT |
GACCAAGGCC |
AAGGTGGCCA |
GTTTCCTATA |
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3281 |
GAACGCCTCT |
AAAAGACCTG |
CAGCAATAGC |
AGCAAGAACT |
GGTATTCTCG |
AGAACTTGCT |
GCGCAGCAGG |
CACTTCTTGG |
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3361 |
CATTTTATGT |
GTATTTAATT |
TCACAATAGC |
TCTATGACAA |
AGTCCACCTT |
TCTCATCTCC |
AGGAAACTGA |
GGTTCAGAGA |
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3441 |
GGTTAAGTAA |
CTTGTCCAAG |
GTCACACAGC |
TAATAGCAAG |
TTGACGTGGA |
GCAATCTGGC |
CTCAGAGCCT |
TTAATTTTAG |
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3521 |
CCACAGACTG |
ATGCTCCCCT |
CTTCATTTAG |
CCAGGCTGCC |
TCTGAAGTTT |
TCTGATTCAA |
GACTTCTGGC |
TTCAGCTTTG |
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3601 |
TACACAGAGA |
TGATTCAATG |
TCAGGTTTTG |
GAGTGAAATC |
TGTTTAATCC |
CAGACAAAAC |
ATTTAGGATT |
ACATCTCAGT |
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3681 |
TTTGTAAGCA |
AGTAGCTCTG |
TGATTTTTAG |
TGAGTTATTT |
AATGCTCTTT |
GGGGCTCAAT |
TTTTCTATCT |
ATAAAATAGG |
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3761 |
GCTAATAATT |
TGCACCTTAT |
AGGGTAAGCT |
TTGAGGACAG |
ATTAGATGAT |
ACGGTGCCTG |
TAAAACACCA |
GGTGTTAGTA |
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3841 |
AGTGTGGCAA |
TGATGGTGAC |
GCTGAGGCTG |
ATGTTTGCTT |
AGCATAGGGT |
TAGGCAGCTG |
GCAGGCAGTA |
AACAGTTGGA |
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3921 |
TAATTTAATG |
GAAAATTTGC |
CAAACTCAGA |
TGCTGTTCAC |
TGCTGAGCAG |
GAGCCCCTTC |
CTGCTGAAAT |
GGTCCTGGGG |
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4001 |
AGTGCAGCAG |
GCTCTCCGGG |
AAGAAATCTA |
CCATCTCTCG |
GGCAGGAGCT |
CAACCTGTGT |
GCAGGTACAG |
GGAGGGCTTC |
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4081 |
CTCACCTGGT |
GCCCACTCAT |
GCATTACGTC |
AGTTATTCCT |
CATCCCTGTC |
CAAAGGATTC |
TTTTCTCCAT |
TGTACAGCTA |
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4161 |
TGAAGCTAGT |
GCTCAAAGAA |
GTGAAGTCAT |
TTACCCCAGG |
CCCCCTGCCA |
GTAAGTGACA |
GGGCCTGGTC |
ACACTTGGGT |
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4241 |
TTATTTATTG |
CCCAGTTCAA |
CAGGTTGTTT |
GACCATAGGC |
GAGATTCTCT |
TCCCTGCACC |
CTGCCGGGTT |
GCTCTTGGTC |
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4321 |
CCTTATTTTA |
TGCTCCCGGG |
TAGAAATGGT |
GTGAGATTAG |
GCAGGGAGTG |
GCTCGCTTCC |
CTGTCCCTGG |
CCCCGCAAAG |
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4401 |
AGTGCTCCCA |
CCTGCCCCGA |
TCCCAGAAAT |
GTCACCATGA |
AGCCTTCATT |
CTTTTGGTTT |
AAAGCTTGGC |
CTCAGTGTCC |
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4481 |
GTACACCATG |
GGGTACTTGG |
CCAGATGGCG |
ACTTTCTCCT |
CTCCAGTCGC |
CCTCCCAGGC |
ACTAGCTTTT |
AGGAGTGCAG |
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4561 |
GGTGCTGCCT |
CTGATAGAAG |
GGCCAGGAGA |
GAGCAGGTTT |
TGGAGTCCTG |
ATGTTATAAG |
GAACAGCTTG |
GGAGGCATAA |
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4641 |
TGAACCCAAC |
ATGATGCTTG |
AGACCAATGT |
CACAGCCCAA |
TTCTGACATT |
CATCATCTGA |
GATCTGAGGA |
CACAGCTGTC |
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4721 |
TCAGTTCATG |
ATCTGAGTGC |
TGGGAAAGCC |
AAGACTTGTT |
CCAGCTTTGT |
CACTGACTTG |
CTGTATAGCC |
TCAACAAGGC |
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4801 |
CCTGACCCTC |
TCTGGGCTTC |
AAACTCTTCA |
CTGTGAAAGG |
AGGAAACCAG |
AGTAGGTGAT |
GTGACACCAG |
GAAAGATGGA |
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4881 |
TGGGTGTGGG |
GGAATGTGCT |
CCTCCCAGCT |
GTCACCCCCT |
CGCCACCCTC |
CCTGCACCAG |
CCTCTCCACC |
TCCTTTGAGC |
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4961 |
CCAGAATTCC |
CCTGTCTAGG |
AGGGCACCTG |
TCTCATGCCT |
AGCCATGGGA |
ATTCTCCATC |
TGTTTTGCTA |
CATTGAACCC |
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5041 |
AGATGCCATT |
CTAACCAAGA |
ATCCTGGCTG |
GGTGCAGGGG |
CTCTCGCCTG |
TAACCCCAGC |
ACTTTGGGAG |
GCCAAGGCAG |
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5121 |
GCGGATCAAG |
AGGTCAGGAG |
TTCAAGACCT |
GCCTGGCCAA |
CACGGTGAAA |
CCTCAGCTCT |
ACTAAAAATA |
CAAAAATTAG |
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5201 |
CCAGGCGTGG |
TGGCACACGC |
CTGTAATCCC |
AGCTATTTGG |
GAAGCTGAGA |
CAGAAGAATT |
TCTTGAACCC |
GGGAGGTGGA |
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5281 |
GGTTTCAGTG |
AGCCGAGATC |
ACGCCACTGC |
ACTCCACCCT |
GGCAGATAAA |
GCGAGACTCT |
GTCTCAAAAA |
AAACCCAAAA |
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5361 |
ACCTATGTTA |
GTGTACAGAG |
GGCCCCAGTG |
AAGTCTTCTC |
CCAGCCCCAC |
TTTGCACAAC |
TGGGGAGAGT |
GAGGCCCCAG |
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5441 |
GACCAGAGGA |
TTCTTGCTAA |
AGGCCAAGTG |
GATAGTGATG |
GCCCTGCCAG |
GGCTAGAAGC |
CACAACCTCT |
GGCCCTGAGG |
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5521 |
CCACTCAGCA |
TATTTAGTGT |
CCCCACCCTG |
CAGAGGCCCA |
ACTCCCTCCT |
GACCACTGAG |
CCCTGTAATG |
ATGGGGGAAT |
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5601 |
TTCCATAAGC |
CATGAAGGAC |
TGCACAAAGT |
TCAGTTGGGA |
AGTGAAAGAG |
AAATTAAAGG |
GAGATGGAAA |
TATACAGCAC |
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5681 |
TAATTTTAGC |
ACCGTCTTTA |
GTTCTAACAA |
CACTAGCTAG |
CTGAAGAAAA |
ATACAAACAT |
GTATTATGTA |
ATGTGTGGTC |
|
5761 |
TGTTCCATTT |
GGATTACTTA |
GAGGCACGAG |
GGCCAGGAGA |
AAGGTGGTGG |
AGAGAAACCA |
GCTTTGCACT |
TCATTTGTTG |
|
5841 |
CTTTATTGGA |
AGGAAACTTT |
TAAAAGTCCA |
AGGGGGTTGA |
AGAATCTCAA |
TATTTGTTAT |
TTCCAGCTTT |
TTTTCTCCAG |
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5921 |
TTTTTCATTT |
CCCAAATTCA |
AGGACACCTT |
TTTCTTTGTA |
TTTTGTTAAG |
ATGATGGTTT |
TGGTTTTGTG |
ACTAGTAGTT |
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6001 |
AACAATGTGG |
CTGCCGGGCA |
TATTCTCCTC |
AGCTAGGACC |
TCAGTTTTCC |
CATCTGTGAA |
GACGGCAGGT |
TCTACCTAGG |
|
6081 |
GGGCTGCAGG |
CTGGTGGTCC |
GAAGCCTGGG |
CATATCTGGA |
GTAGAAGGAT |
CACTGTGGGG |
CAGGGCAGGT |
TCTGTGTTGC |
|
6161 |
TGTGGATGAC |
GTTGACTTTG |
ACCATTGCTC |
GGCAGAGCCT |
GCTCTCGCTG |
GTTCAGCCAC |
AGGCCCCACC |
ACTCCCTATT |
|
6241 |
GTCTCAGCCC |
CGGGTATGAA |
ACATGTATTC |
CTCACTGGCC |
TATCACCTGA |
AGCCTTTGAA |
TTTGCAACAC |
CTGCCAACCC |
|
6321 |
CTCCCTCAAA |
AGAGTTGCCC |
TCTCAGATCC |
TTTTGATGTA |
AGGTTTGGTG |
TTGAGACTTA |
TTTCACTAAA |
TTCTCATACA |
|
6401 |
TAAACATCAC |
TTTATGTATG |
AGGCAAAATG |
AGGACCAGGG |
AGATGAATGA |
CTTGTCCTGG |
CTCATACACC |
TGGAAAGTGA |
|
6481 |
CAGAGTCAGA |
TTAGATCCCA |
GGTCTATCTG |
AAGTTAAAAG |
AGGTGTCTTT |
TCACTTCCCA |
CCTCCTCCAT |
CTACTTTAAA |
|
6561 |
GCAGCACAAA |
CCCCTGCTTT |
CAAGGAGAGA |
TGAGCGTCTC |
TAAAGCCCCT |
GACAGCAAGA |
GCCCAGAACT |
GGGACACCAT |
|
6641 |
TAGTGACCCA |
GACGGCAGGT |
AAGCTGACTG |
CAGGAGCATC |
AGCCTATTCT |
TGTGTCTGGG |
ACCACAGAGC |
ATTGTGGGGA |
|
6721 |
CAGCCCCGTC |
TCTTGGGAAA |
AAAACCCTAA |
GGGCTGAGGA |
TCCTTGTGAG |
TGTTGGGTGG |
GAACAGCTCC |
CAGGAGGTTT |
|
6801 |
AATCACAGCC |
CCTCCATGCT |
CTCTAGCTGT |
TGCCATTGTG |
CAAGATGCAT |
TTCCCTTCTG |
TGCAGCAGTT |
TCCCTGGCCA |
|
6881 |
CTAAATAGTG |
GGATTAGATA |
GAAGCCCTCC |
AAGGGCTTCC |
AGCTTGACAT |
GATTCTTGAT |
TCTGATCTGG |
CCCGATTCCT |
|
6961 |
GGATAATCGT |
GGGCAGGCCC |
ATTCCTCTTC |
TTGTGCCTCA |
TTTTCTTCTT |
TTGTAAAACA |
ATGGCTGTAC |
CATTTGCATC |
|
7041 |
TTAGGGTCAT |
TGCAGATGTA |
AGTGTTGCTG |
TCCAGAGCCT |
GGGTGCAGGA |
CCTAGATGTA |
GGATTCTGGT |
TCTGCTACTT |
|
7121 |
CCTCAGTGAC |
ATTGAATAGC |
TGACCTAATC |
TCTCTGGCTT |
TGGTTTCTTC |
ATCTGTAAAA |
GAAGGATATT |
AGCATTAGCA |
|
7201 |
CCTCACGGGA |
TTGTTACAAG |
AAAGCAATGA |
ATTAACACAT |
GTGAGCACGG |
AGAACAGTGC |
TTGGCATATG |
GTAAGCACTA |
|
7281 |
CGTACATTTT |
GCTATTCTTC |
TGATTCTTTC |
AGTGTTACTG |
ATGTCGGCAA |
GTACTTGGCA |
CAGGCTGGTT |
TAATAATCCC |
|
7361 |
TAGGCACTTC |
CACGTGGTGT |
CAATCCCTGA |
TCACTGGGAG |
TCATCATGTG |
CCTTGACTCG |
GGGCCTGGCC |
CCCCCATCTC |
|
7441 |
TGTCTTGCAG |
GACAATGCCG |
TCTTCTGTCT |
CGTGGGGCAT |
CCTCCTGCTG |
GCAGGCCTGT |
GCTGCCTGGT |
CCCTGTCTCC |
|
7521 |
CTGGCTGAGG |
ATCCCCAGGG |
AGATGCTGCC |
CAGAAGACAG |
ATACATCCCA |
CCATGATCAG |
GATCACCCAA |
CCTTCAACAA |
|
7601 |
GATCACCCCC |
AACCTGGCTG |
AGTTCGCCTT |
CAGCCTATAC |
CGCCAGCTGG |
CACACCAGTC |
CAACAGCACC |
AATATCTTCT |
|
7681 |
TCTCCCCAGT |
GAGCATCGCT |
ACAGCCTTTG |
CAATGCTCTC |
CCTGGGGACC |
AAGGCTGACA |
CTCACGATGA |
AATCCTGGAG |
|
7761 |
GGCCTGAATT |
TCAACCTCAC |
GGAGATTCCG |
GAGGCTCAGA |
TCCATGAAGG |
CTTCCAGGAA |
CTCCTCCGTA |
CCCTCAACCA |
|
7841 |
GCCAGACAGC |
CAGCTCCAGC |
TGACCACCGG |
CAATGGCCTG |
TTCCTCAGCG |
AGGGCCTGAA |
GCTAGTGGAT |
AAGTTTTTGG |
|
7921 |
AGGATGTTAA |
AAAGTTGTAC |
CACTCAGAAG |
CCTTCACTGT |
CAACTTCGGG |
GACACCGAAG |
AGGCCAAGAA |
ACAGATCAAC |
|
8001 |
GATTACGTGG |
AGAAGGGTAC |
TCAAGGGAAA |
ATTGTGGATT |
TGGTCAAGGA |
GCTTGACAGA |
GACACAGTTT |
TTGCTCTGGT |
|
8081 |
GAATTACATC |
TTCTTTAAAG |
GTAAGGTTGC |
TCAACCAGCC |
TGAGCTGTTC |
CCATAGAAAC |
AAGCAAAAAT |
ATTCTCAAAC |
|
8161 |
CATCAGTTCT |
TGAACTCTCC |
TTGGCAATGC |
ATTATGGGCC |
ATAGCAATGC |
TTTTCAGCGT |
GGATTCTTCA |
GTTTTCTACA |
|
8241 |
CACAAACACT |
AAAATGTTTT |
CCATCATTGA |
GTAATTTGAG |
GAAATAATAG |
ATTAAACTGT |
CAAAACTACT |
GACAGCTCTG |
|
8321 |
CAGAACTTTT |
CAGAGCCTTT |
AATGTCCTTG |
TGTATACTGT |
ATATGTAGAA |
TATATAATGC |
TTAGAACTAT |
AGAACAAATT |
|
8401 |
GTAATACACT |
GCATAAAGGG |
ATAGTTTCAT |
GGAACATACT |
TTACACGACT |
CTAGTGTCCC |
AGAATCAGTA |
TCAGTTTTGC |
|
8481 |
AATCTGAAAG |
ACCTGGGTTC |
AAATCCTGCC |
TCTAACACAA |
TTAGCTTTTG |
ACAAAAACAA |
TGCATTCTAC |
CTCTTTGAGG |
|
8561 |
TGCTAATTTC |
TCATCTTAGC |
ATGGACAAAA |
TACCATTCTT |
GCTGTCAGGT |
TTTTTTAGGA |
TTAAACAAAT |
GACAAAGACT |
|
8641 |
GTGGGGATGG |
TGTGTGGCAT |
ACAGCAGGTG |
ATGGACTCTT |
CTGTATCTCA |
GGCTGCCTTC |
CTGCCCCTGA |
GGGGTTAAAA |
|
8721 |
TGCCAGGGTC |
CTGGGGGCCC |
CAGGGCATTC |
TAAGCCAGCT |
CCCACTGTCC |
CAGGAAAACA |
GCATAGGGGA |
GGGGAGGTGG |
|
8801 |
GAGGCAAGGC |
CAGGGGCTGC |
TTCCTCCACT |
CTGAGGCTCC |
CTTGCTCTTG |
AGGCAAAGGA |
GGGCAGTGGA |
GAGCAGCCAG |
|
8881 |
GCTGCAGTCA |
GCACAGCTAA |
AGTCCTGGCT |
CTGCTGTGGC |
CTTAGTGGGG |
GCCCAGGTCC |
CTCTCCAGCC |
CCAGTCTCCT |
|
8961 |
CCTTCTGTCC |
AATGAGAAAG |
CTGGGATCAG |
GGGTCCCTGA |
GGCCCCTGTC |
CACTCTGCAT |
GCCTCGATGG |
TGAAGCTCTG |
|
9041 |
TTGGTATGGC |
AGAGGGGAGG |
CTGCTCAGGC |
ATCTGCATTT |
CCCCTGCCAA |
TCTAGAGGAT |
GAGGAAAGCT |
CTCAGGAATA |
|
9121 |
GTAAGCAGAA |
TGTTTGCCCT |
GGATGAATAA |
CTGAGCTGCC |
AATTAACAAG |
GGGCAGGGAG |
CCTTAGACAG |
AAGGTACCAA |
|
9201 |
ATATGCCTGA |
TGCTCCAACA |
TTTTATTTGT |
AATATCCAAG |
ACACCCTCAA |
ATAAACATAT |
GATTCCAATA |
AAAATGCACA |
|
9281 |
GCCACGATGG |
CATCTCTTAG |
CCTGACATCG |
CCACGATGTA |
GAAATTCTGC |
ATCTTCCTCT |
AGTTTTGAAT |
TATCCCCACA |
|
9361 |
CAATCTTTTT |
CGGCAGCTTG |
GATGGTCAGT |
TTCAGCACCT |
TTTACAGATG |
ATGAAGCTGA |
GCCTCGAGGG |
ATGTGTGTCG |
|
9441 |
TCAAGGGGGC |
TCAGGGCTTC |
TCAGGGAGGG |
GACTCATGGT |
TTCTTTATTC |
TGCTACACTC |
TTCCAAACCT |
TCACTCACCC |
|
9521 |
CTGGTGATGC |
CCACCTTCCC |
CTCTCTCCAG |
GCAAATGGGA |
GAGACCCTTT |
GAAGTCAAGG |
ACACCGAGGA |
AGAGGACTTC |
|
9601 |
CACGTGGACC |
AGGTGACCAC |
CGTGAAGGTG |
CCTATGATGA |
AGCGTTTAGG |
CATGTTTAAC |
ATCCAGCACT |
GTAAGAAGCT |
|
9681 |
GTCCAGCTGG |
GTGCTGCTGA |
TGAAATACCT |
GGGCAATGCC |
ACCGCCATCT |
TCTTCCTGCC |
TGATGAGGGG |
AAACTACAGC |
|
9761 |
ACCTGGAAAA |
TGAACTCACC |
CACGATATCA |
TCACCAAGTT |
CCTGGAAAAT |
GAAGACAGAA |
GGTGATTCCC |
CAACCTGAGG |
|
9841 |
GTGACCAAGA |
AGCTGCCCAC |
ACCTCTTAGC |
CATGTTGGGA |
CTGAGGCCCA |
TCAGGACTGG |
CCAGAGGGCT |
GAGGAGGGTG |
|
9921 |
AACCCCACAT |
CCCTGGGTCA |
CTGCTACTCT |
GTATAAACTT |
GGCTTCCAGA |
ATGAGGCCAC |
CACTGAGTTC |
AGGCAGCGCC |
|
10001 |
ATCCATGCTC |
CATGAGGAGG |
ACAGTACCCA |
GGGGTGAGGA |
GGTAAAGGTC |
TCGTCCCTGG |
GGACTTCCCA |
CTCCAGTGTG |
|
10081 |
GACACTGTCC |
CTTCCCAATA |
TCCAGTGCCC |
AGGGCAGGGA |
CAGCAGCACC |
ACCACACGTT |
CTGGCAGAAC |
CAAAAAGGAA |
|
10161 |
CAGATGGGCT |
TCCTGGCAAA |
GGCAGCAGTG |
GAGTGTGGAG |
TTCAAGGGTA |
GAATGTCCCT |
GGGGGGACGG |
GGGAAGAGCC |
|
10241 |
TGTGTGGCAA |
GGCCCAGAAA |
AGCAAGGTTC |
GGAATTGGAA |
CAGCCAGGCC |
ATGTTCGCAG |
AAGGCTTGCG |
TTTCTCTGTC |
|
10321 |
ACTTTATCGG |
TGCTGTTAGA |
TTGGGTGTCC |
TGTAGTAAGT |
GATACTTAAA |
CATGAGCCAC |
ACATTAGTGT |
ATGTGTGTGC |
|
10401 |
ATTCGTGATT |
ATGCCCATGC |
CCTGCTGATC |
TAGTTCGTTT |
TGTACACTGT |
AAAACCAAGA |
TGAAAATACA |
AAAGGTGTCG |
|
10481 |
GGTTCATAAT |
AGGAATCGAG |
GCTGGAATTT |
CTCTGTTCCA |
TGCCAGCACC |
TCCTGAGGTC |
TCTGCTCCAG |
GGGTTGAGAA |
|
10561 |
AGAACAAAGA |
GGCTGAGAGG |
GTAACGGATC |
AGAGAGCCCA |
GAGCCAAGCT |
GCCCGCTCAC |
ACCAGACCCT |
GCTCAGGGTG |
|
10641 |
GCATTGTCTC |
CCCATGGAAA |
ACCAGAGAGG |
AGCACTCAGC |
CTGGTGTGGT |
CACTCTTCTC |
TTATCCACTA |
AACGGTTGTC |
|
10721 |
ACTGGGCACT |
GCCACCAGCC |
CCGTGTTTCT |
CTGGGTGTAG |
GGCCCTGGGG |
ATGTTACAGG |
CTGGGGGCCA |
GGTGACCCAA |
|
10801 |
CACTACAGGG |
CAAGATGAGA |
CAGGCTTCCA |
GGACACCTAG |
AATATCAGAG |
GAGGTGGCAT |
TTCAAGCTTT |
TGTGATTCAT |
|
10881 |
TCGATGTTAA |
CATTCTTTGA |
CTCAATGTAG |
AAGAGCTAAA |
AGTAGAACAA |
ACCAAAGCCG |
AGTTCCCATC |
TTAGTGTGGG |
|
10961 |
TGGAGGACAC |
AGGAGTAAGT |
GGCAGAAATA |
ATCAGAAAAG |
AAAACACTTG |
CACTGTGGTG |
GGTCCCAGAA |
GAACAAGAGG |
|
11041 |
AATGCTGTGC |
CATGCCTTGA |
ATTTCTTTTC |
TGCACGACAG |
GTCTGCCAGC |
TTACATTTAC |
CCAAACTGTC |
CATTACTGGA |
|
11121 |
ACCTATGATC |
TGAAGAGCGT |
CCTGGGTCAA |
CTGGGCATCA |
CTAAGGTCTT |
CAGCAATGGG |
GCTGACCTCT |
CCGGGGTCAC |
|
11201 |
AGAGGAGGCA |
CCCCTGAAGC |
TCTCCAAGGT |
GAGATCACCC |
TGACGACCTT |
GTTGCACCCT |
GGTATCTGTA |
GGGAAGAATG |
|
11281 |
TGTGGGGGCT |
GCAGCTCTGT |
CCTGAGGCTG |
AGGAAGGGGC |
CGAGGGAAAC |
AAATGAAGAC |
CCAGGCTGAG |
CTCCTGAAGA |
|
11361 |
TGCCCGTGAT |
TCACTGACAC |
GGGACGTGGT |
CAAACAGCAA |
AGCCAGGCAG |
GGGACTGCTG |
TGCAGCTGGC |
ACTTTCGGGG |
|
11441 |
CCTCCCTTGA |
GGTTGTGTCA |
CTGACCCTGA |
ATTTCAACTT |
TGCCCAAGAC |
CTTCTAGACA |
TTGGGCCTTG |
ATTTATCCAT |
|
11521 |
ACTGACACAG |
AAAGGTTTGG |
GCTAAGTTGT |
TTCAAAGGAA |
TTTCTGACTC |
CTTCGATCTG |
TGAGATTTGG |
TGTCTGAATT |
|
11601 |
AATGAATGAT |
TTCAGCTAAA |
GATGACACTT |
ATTTTGGAAA |
ACTAAAGGCG |
ACCAATGAAC |
AACTGCAGTT |
CCATGAATGG |
|
11681 |
CTGCATTATC |
TTGGGGTCTG |
GGCACTGTGA |
AGGTCACTGC |
CAGGGTCCGT |
GTCCTCAAGG |
AGCTTCAAGC |
CGTGTACTAG |
|
11761 |
AAAGGAGAGA |
GCCCTGGAGG |
CAGACGTGGA |
GTGACGATGC |
TCTTCCCTGT |
TCTGAGTTGT |
GGGTGCACCT |
GAGCAGGGGG |
|
11841 |
AGAGGCGCTT |
GTCAGGAAGA |
TGGACAGAGG |
GGAGCCAGCC |
CCATCAGCCA |
AAGCCTTGAG |
GAGGAGCAAG |
GCCTATGTGA |
|
11921 |
CAGGGAGGGA |
GAGGATGTGC |
AGGGCCAGGG |
CCGTCCAGGG |
GGAGTGAGCG |
CTTCCTGGGA |
GGTGTCCACG |
TGAGCCTTGC |
|
12001 |
TCGAGGCCTG |
GGATCAGCCT |
TACAACGTGT |
CTCTGCTTCT |
CTCCCCTCCA |
GGCCGTGCAT |
AAGGCTGTGC |
TGACCATCGA |
|
12081 |
CGAGAAAGGG |
ACTGAAGCTG |
CTGGGGCCAT |
GTTTTTAGAG |
GCCATACCCA |
TGTCTATCCC |
CCCCGAGGTC |
AAGTTCAACA |
|
12161 |
AACCCTTTGT |
CTTCTTAATG |
ATTGAACAAA |
ATACCAAGTC |
TCCCCTCTTC |
ATGGGAAAAG |
TGGTGAATCC |
CACCCAAAAA |
|
12241 |
TAACTGCCTC |
TCGCTCCTCA |
ACCCCTCCCC |
TCCATCCCTG |
GCCCCCTCCC |
TGGATGACAT |
TAAAGAAGGG |
TTGAGCTGGT |
|
12321 |
CCCTGCCTGC |
ATGTGACTGT |
AAATCCCTCC |
CATGTTTTCT |
CTGAGTCTCC |
CTTTGCCTGC |
TGAGGCTGTA |
TGTGGGCTCC |
|
12401 |
AGGTAACAGT |
GCTGTCTTCG |
GGCCCCCTGA |
ACTGTGTTCA |
TGGAGCATCT |
GGCTGGGTAG |
GCACATGCTG |
GGCTTGAATC |
|
12481 |
CAGGGGGGAC |
TGAATCCTCA |
GCTTACGGAC |
CTGGGCCCAT |
CTGTTTCTGG |
AGGGCTCCAG |
TCTTCCTTGT |
CCTGTCTTGG |
|
12561 |
AGTCCCCAAG |
AAGGAATCAC |
AGGGGAGGAA |
CCAGATACCA |
GCCATGACCC |
CAGGCTCCAC |
CAAGCATCTT |
CATGTCCCCC |
|
12641 |
TGCTCATCCC |
CCACTCCCCC |
CCACCCAGAG |
TTGCTCATCC |
TGCCAGGGCT |
GGCTGTGCCC |
ACCCCAAGGC |
TGCCCTCCTG |
|
12721 |
GGGGCCCCAG |
AACTGCCTGA |
TCGTGCCGTG |
GCCCAGTTTT |
GTGGCATCTG |
CAGCAACACA |
AGAGAGAGGA |
CAATGTCCTC |
|
12801 |
CTCTTGACCC |
GCTGTCACCT |
AACCAGACTC |
GGGCCCTGCA |
CCTCTCAGGC |
ACTTCTGGAA |
AATGACTGAG |
GCAGATTCTT |
|
12881 |
CCTGAAGCCC |
ATTCTCCATG |
GGGCAACAAG |
GACACCTATT |
CTGTCCTTGT |
CCTTCCATCG |
CTGCCCCAGA |
AAGCCTCACA |
|
12961 |
TATCTCCGTT |
TAGAATCAGG |
TCCCTTCTCC |
CCAGATGAAG |
AGGAGGGTCT |
CTGCTTTGTT |
TTCTCTATCT |
CCTCCTCAGA |
|
13041 |
CTTGACCAGG |
CCCAGCAGGC |
CCCAGAAGAC |
CATTACCCTA |
TATCCCTTCT |
CCTCCCTAGT |
CACATGGCCA |
TAGGCCTGCT |
|
13121 |
GATGGCTCAG |
GAAGGCCATT |
GCAAGGACTC |
CTCAGCTATG |
GGAGAGGAAG |
CACATCACCC |
ATTGACCCCC |
GCAACCCCTC |
|
13201 |
CCTTTCCTCC |
TCTGAGTCCC |
GACTGGGGCC |
ACATGCAGCC |
TGACTTCTTT |
GTGCCTGTTG |
CTGTCCCTGC |
AGTCTTCAGA |
|
13281 |
GGGCCACCGC |
AGCTCCAGTG |
CCACGGCAGG |
AGGCTGTTCC |
TGAATAGCCC |
CTGTGGTAAG |
GGCCAGGAGA |
GTCCTTCCAT |
|
13361 |
CCTCCAAGGC |
CCTGCTAAAG |
GACACAGCAG |
CCAGGAAGTC |
CCCTGGGCCC |
CTAGCTGAAG |
GACAGCCTGC |
TCCCTCCGTC |
|
13441 |
TCTACCAGGA |
ATGGCCTTGT |
CCTATGGAAG |
GCACTGCCCC |
ATCCCAAACT |
AATCTAGGAA |
TCACTGTCTA |
ACCACTCACT |
|
13521 |
GTCATGAATG |
TGTACTTAAA |
GGATGAGGTT |
GAGTCATACC |
AAATAGTGAT |
TTCGATAGTT |
CAAAATGGTG |
AAATTAGCAA |
|
13601 |
TTCTACATGA |
TTCAGTCTAA |
TCAATGGATA |
CCGACTGTTT |
CCCACACAAG |
TCTCCTGTTC |
TCTTAAGCTT |
ACTCACTGAC |
|
13681 |
AGCCTTTCAC |
TCTCCACAAA |
TACATTAAAG |
ATATGGCCAT |
CACCAAGCCC |
CCTAGGATGA |
CACCAGACCT |
GAGAGTCTGA |
|
13761 |
AGACCTGGAT |
CCAAGTTCTG |
ACTTTTCCCC |
CTGACAGCTG |
TGTGACCTTC |
GTGAAGTCGC |
CAAACCTCTC |
TGAGCCCCAG |
|
13841 |
TCATTGCTAG |
TAAGACCTGC |
CTTTGAGTTG |
GTATGATGTT |
CAAGTTAGAT |
AACAAAATGT |
TTATACCCAT |
TAGAACAGAG |
|
13921 |
AATAAATAGA |
ACTACATTTC |
TTGCAC |
|
|
|
|
|
|
|
|
|
|
|
|
>ref|Gene_ID:5265|SERPINA1|NC_000014.8:94843083...94857028 (-)
GGGCAGGAACTGGGCACTGTGCCCAGGGCATGCACTGCCTCCACGCAGCAACCCTCAGAGTCCTGAGCTGAACCAAGAAG
GAGGAGGGGGTCGGGCCTCCGAGGAAGGCCTAGCCGCTGCTGCTGCCAGGAATTCCAGGTTGGAGGGGCGGCAACCTCCT
GCCAGCCTTCAGGCCACTCTCCTGTGCCTGCCAGAAGAGACAGAGCTTGAGGAGAGCTTGAGGAGAGCAGGAAAGGTGGG
ACATTGCTGCTGCTGCTCACTCAGTTCCACAGGTGGGAGGGACAGCAGGGCTTAGAGTGGGGGTCATTGTGCAGATGGGA
AAACAAAGGCCCAGAGAGGGGAAGAAATGCCCAGGAGCTACCGAGGGCAGGCGACCTCAACCACAGCCCAGTGCTGGAGC
TGTGAGTGGATGTAGAGCAGCGGAATATCCATTCAGCCAGCTCAGGGGAAGGACAGGGGCCCTGAAGCCAGGGGATGGAG
CTGCAGGGAAGGGAGCTCAGAGAGAAGGGGAGGGGAGTCTGAGCTCAGTTTCCCGCTGCCTGAAAGGAGGGTGGTACCTA
CTCCCTTCACAGGGTAACTGAATGAGAGACTGCCTGGAGGAAAGCTCTTCAAGTGTGGCCCACCCCACCCCAGTGACACC
AGCCCCTGACACGGGGGAGGGAGGGCAGCATCAGGAGGGGCTTTCTGGGCACACCCAGTACCCGTCTCTGAGCTTTCCTT
GAACTGTTGCATTTTAATCCTCACAGCAGCTCAACAAGGTACATACCGTCACCATCCCCATTTTACAGATAGGGAAATTG
AGGCTCGGAGCGGTTAAACAACTCACCTGAGGCCTCACAGCCAGTAAGTGGGTTCCCTGGTCTGAATGTGTGTGCTGGAG
GATCCTGTGGGTCACTCGCCTGGTAGAGCCCCAAGGTGGAGGCATAAATGGGACTGGTGAATGACAGAAGGGGCAAAAAT
GCACTCATCCATTCACTCTGCAAGTATCTACGGCACGTACGCCAGCTCCCAAGCAGGTTTGCGGGTTGCACAGCGGGCGA
TGCAATCTGATTTAGGCTTTTAAAGGGATTGCAATCAAGTGGGGCCCCACTAGCCTCAACCCTGTACCTCCCCTCCCCTC
CACCCCCAGCAGTCTCCAAAGGCCTCCAACAACCCCAGAGTGGGGGCCATGTATCCAAAGAAACTCCAAGCTGTATACGG
ATCACACTGGTTTTCCAGGAGCAAAAACAGAAACAGGCCTGAGGCTGGTCAAAATTGAACCTCCTCCTGCTCTGAGCAGC
CTGGGGGGCAGACTAAGCAGAGGGCTGTGCAGACCCACATAAAGAGCCTACTGTGTGCCAGGCACTTCACCCGAGGCACT
TCACAAGCATGCTTGGGAATGAAACTTCCAACTCTTTGGGATGCAGGTGAAACAGTTCCTGGTTCAGAGAGGTGAAGCGG
CCTGCCTGAGGCAGCACAGCTCTTCTTTACAGATGTGCTTCCCCACCTCTACCCTGTCTCACGGCCCCCCATGCCAGCCT
GACGGTTGTGTCTGCCTCAGTCATGCTCCATTTTTCCATCGGGACCATCAAGAGGGTGTTTGTGTCTAAGGCTGACTGGG
TAACTTTGGATGAGCGGTCTCTCCGCTCTGAGCCTGTTTCCTCATCTGTCAAATGGGCTCTAACCCACTCTGATCTCCCA
GGGCGGCAGTAAGTCTTCAGCATCAGGCATTTTGGGGTGACTCAGTAAATGGTAGATCTTGCTACCAGTGGAACAGCCAC
TAAGGATTCTGCAGTGAGAGCAGAGGGCCAGCTAAGTGGTACTCTCCCAGAGACTGTCTGACTCACGCCACCCCCTCCAC
CTTGGACACAGGACGCTGTGGTTTCTGAGCCAGGTACAATGACTCCTTTCGGTAAGTGCAGTGGAAGCTGTACACTGCCC
AGGCAAAGCGTCCGGGCAGCGTAGGCGGGCGACTCAGATCCCAGCCAGTGGACTTAGCCCCTGTTTGCTCCTCCGATAAC
TGGGGTGACCTTGGTTAATATTCACCAGCAGCCTCCCCCGTTGCCCCTCTGGATCCACTGCTTAAATACGGACGAGGACA
GGGCCCTGTCTCCTCAGCTTCAGGCACCACCACTGACCTGGGACAGTGAATCGTAAGTATGCCTTTCACTGCGAGAGGTT
CTGGAGAGGCTTCTGAGCTCCCCATGGCCCAGGCAGGCAGCAGGTCTGGGGCAGGAGGGGGGTTGTGGAGTGGGTATCCG
CCTGCTGAGGTGCAGGGCAGATGGAGAGGCTGCAGCTGAGCTCCTATTTTCATAATAACAGCAGCCATGAGGGTTGTGTC
CTGTTTCCCAGTCCTGCCCGGTCCCCCCTCGGTACCTCCTGGTGGATACACTGGTTCCTGTAAGCAGAAGTGGATGAGGG
TGTCTAGGTCTGCAGTCCTGGCACCCCAGGATGGGGGACACCAGCCAAGATACAGCAACAGCAACAAAGCGCAGCCATTT
CTTTCTGTTTGCACAGCTCCTCTGTCTGTCGGGGGCTCCTGTCTGTTGTCTCCTATAAGCCTCACCACCTCTCCTACTGC
TTGGGCATGCATCTTTCTCCCCTTCTATAGATGAGGAGGTTAAGGTCCAGAGAGGGGTGGGGAGGAACGCCGGCTCACAT
TCTCCATCCCCTCCAGATATGACCAGGAACAGACCTGTGCCAGGCCTCAGCCTTACATCAAAATGGGCCTCCCCATGCAC
CGTGGACCTCTGGGCCCTCCTGTCCCAGTGGAGGACAGGAAGCTGTGAGGGGCACTGTCACCCAGGGCTCAAGCTGGCAT
TCCTGAATAATCGCTCTGCACCAGGCCACGGCTAAGCTCAGTGCGTGATTAAGCCTCATAACCCTCCAAGGCAGTTACTA
GTGTGATTCCCATTTTACAGATGAGGAAGATGGGGACAGAGAGGTGAATAACTGGCCCCAAATCACACACCATCCATAAT
TCGGGCTCAGGCACCTGGCTCCAGTCCCCAAACTCTTGAACCTGGCCCTAGTGTCACTGTTTCTCTTGGGTCTCAGGCGC
TGGATGGGGAACAGGAAACCTGGGCTGGACTTGAGGCCTCTCTGATGCTCGGTGACTTCAGACAGTTGCTCAACCTCTCT
GTTCTCTTGGGCAAAACATGATAACCTTTGACTTCTGTCCCCTCCCCTCACCCCACCCGACCTTGATCTCTGAAGTGTTG
GAAGGATTTAATTTTTCCTGCACTGAGTTTTGGAGACAGGTCAAAAAGATGACCAAGGCCAAGGTGGCCAGTTTCCTATA
GAACGCCTCTAAAAGACCTGCAGCAATAGCAGCAAGAACTGGTATTCTCGAGAACTTGCTGCGCAGCAGGCACTTCTTGG
CATTTTATGTGTATTTAATTTCACAATAGCTCTATGACAAAGTCCACCTTTCTCATCTCCAGGAAACTGAGGTTCAGAGA
GGTTAAGTAACTTGTCCAAGGTCACACAGCTAATAGCAAGTTGACGTGGAGCAATCTGGCCTCAGAGCCTTTAATTTTAG
CCACAGACTGATGCTCCCCTCTTCATTTAGCCAGGCTGCCTCTGAAGTTTTCTGATTCAAGACTTCTGGCTTCAGCTTTG
TACACAGAGATGATTCAATGTCAGGTTTTGGAGTGAAATCTGTTTAATCCCAGACAAAACATTTAGGATTACATCTCAGT
TTTGTAAGCAAGTAGCTCTGTGATTTTTAGTGAGTTATTTAATGCTCTTTGGGGCTCAATTTTTCTATCTATAAAATAGG
GCTAATAATTTGCACCTTATAGGGTAAGCTTTGAGGACAGATTAGATGATACGGTGCCTGTAAAACACCAGGTGTTAGTA
AGTGTGGCAATGATGGTGACGCTGAGGCTGATGTTTGCTTAGCATAGGGTTAGGCAGCTGGCAGGCAGTAAACAGTTGGA
TAATTTAATGGAAAATTTGCCAAACTCAGATGCTGTTCACTGCTGAGCAGGAGCCCCTTCCTGCTGAAATGGTCCTGGGG
AGTGCAGCAGGCTCTCCGGGAAGAAATCTACCATCTCTCGGGCAGGAGCTCAACCTGTGTGCAGGTACAGGGAGGGCTTC
CTCACCTGGTGCCCACTCATGCATTACGTCAGTTATTCCTCATCCCTGTCCAAAGGATTCTTTTCTCCATTGTACAGCTA
TGAAGCTAGTGCTCAAAGAAGTGAAGTCATTTACCCCAGGCCCCCTGCCAGTAAGTGACAGGGCCTGGTCACACTTGGGT
TTATTTATTGCCCAGTTCAACAGGTTGTTTGACCATAGGCGAGATTCTCTTCCCTGCACCCTGCCGGGTTGCTCTTGGTC
CCTTATTTTATGCTCCCGGGTAGAAATGGTGTGAGATTAGGCAGGGAGTGGCTCGCTTCCCTGTCCCTGGCCCCGCAAAG
AGTGCTCCCACCTGCCCCGATCCCAGAAATGTCACCATGAAGCCTTCATTCTTTTGGTTTAAAGCTTGGCCTCAGTGTCC
GTACACCATGGGGTACTTGGCCAGATGGCGACTTTCTCCTCTCCAGTCGCCCTCCCAGGCACTAGCTTTTAGGAGTGCAG
GGTGCTGCCTCTGATAGAAGGGCCAGGAGAGAGCAGGTTTTGGAGTCCTGATGTTATAAGGAACAGCTTGGGAGGCATAA
TGAACCCAACATGATGCTTGAGACCAATGTCACAGCCCAATTCTGACATTCATCATCTGAGATCTGAGGACACAGCTGTC
TCAGTTCATGATCTGAGTGCTGGGAAAGCCAAGACTTGTTCCAGCTTTGTCACTGACTTGCTGTATAGCCTCAACAAGGC
CCTGACCCTCTCTGGGCTTCAAACTCTTCACTGTGAAAGGAGGAAACCAGAGTAGGTGATGTGACACCAGGAAAGATGGA
TGGGTGTGGGGGAATGTGCTCCTCCCAGCTGTCACCCCCTCGCCACCCTCCCTGCACCAGCCTCTCCACCTCCTTTGAGC
CCAGAATTCCCCTGTCTAGGAGGGCACCTGTCTCATGCCTAGCCATGGGAATTCTCCATCTGTTTTGCTACATTGAACCC
AGATGCCATTCTAACCAAGAATCCTGGCTGGGTGCAGGGGCTCTCGCCTGTAACCCCAGCACTTTGGGAGGCCAAGGCAG
GCGGATCAAGAGGTCAGGAGTTCAAGACCTGCCTGGCCAACACGGTGAAACCTCAGCTCTACTAAAAATACAAAAATTAG
CCAGGCGTGGTGGCACACGCCTGTAATCCCAGCTATTTGGGAAGCTGAGACAGAAGAATTTCTTGAACCCGGGAGGTGGA
GGTTTCAGTGAGCCGAGATCACGCCACTGCACTCCACCCTGGCAGATAAAGCGAGACTCTGTCTCAAAAAAAACCCAAAA
ACCTATGTTAGTGTACAGAGGGCCCCAGTGAAGTCTTCTCCCAGCCCCACTTTGCACAACTGGGGAGAGTGAGGCCCCAG
GACCAGAGGATTCTTGCTAAAGGCCAAGTGGATAGTGATGGCCCTGCCAGGGCTAGAAGCCACAACCTCTGGCCCTGAGG
CCACTCAGCATATTTAGTGTCCCCACCCTGCAGAGGCCCAACTCCCTCCTGACCACTGAGCCCTGTAATGATGGGGGAAT
TTCCATAAGCCATGAAGGACTGCACAAAGTTCAGTTGGGAAGTGAAAGAGAAATTAAAGGGAGATGGAAATATACAGCAC
TAATTTTAGCACCGTCTTTAGTTCTAACAACACTAGCTAGCTGAAGAAAAATACAAACATGTATTATGTAATGTGTGGTC
TGTTCCATTTGGATTACTTAGAGGCACGAGGGCCAGGAGAAAGGTGGTGGAGAGAAACCAGCTTTGCACTTCATTTGTTG
CTTTATTGGAAGGAAACTTTTAAAAGTCCAAGGGGGTTGAAGAATCTCAATATTTGTTATTTCCAGCTTTTTTTCTCCAG
TTTTTCATTTCCCAAATTCAAGGACACCTTTTTCTTTGTATTTTGTTAAGATGATGGTTTTGGTTTTGTGACTAGTAGTT
AACAATGTGGCTGCCGGGCATATTCTCCTCAGCTAGGACCTCAGTTTTCCCATCTGTGAAGACGGCAGGTTCTACCTAGG
GGGCTGCAGGCTGGTGGTCCGAAGCCTGGGCATATCTGGAGTAGAAGGATCACTGTGGGGCAGGGCAGGTTCTGTGTTGC
TGTGGATGACGTTGACTTTGACCATTGCTCGGCAGAGCCTGCTCTCGCTGGTTCAGCCACAGGCCCCACCACTCCCTATT
GTCTCAGCCCCGGGTATGAAACATGTATTCCTCACTGGCCTATCACCTGAAGCCTTTGAATTTGCAACACCTGCCAACCC
CTCCCTCAAAAGAGTTGCCCTCTCAGATCCTTTTGATGTAAGGTTTGGTGTTGAGACTTATTTCACTAAATTCTCATACA
TAAACATCACTTTATGTATGAGGCAAAATGAGGACCAGGGAGATGAATGACTTGTCCTGGCTCATACACCTGGAAAGTGA
CAGAGTCAGATTAGATCCCAGGTCTATCTGAAGTTAAAAGAGGTGTCTTTTCACTTCCCACCTCCTCCATCTACTTTAAA
GCAGCACAAACCCCTGCTTTCAAGGAGAGATGAGCGTCTCTAAAGCCCCTGACAGCAAGAGCCCAGAACTGGGACACCAT
TAGTGACCCAGACGGCAGGTAAGCTGACTGCAGGAGCATCAGCCTATTCTTGTGTCTGGGACCACAGAGCATTGTGGGGA
CAGCCCCGTCTCTTGGGAAAAAAACCCTAAGGGCTGAGGATCCTTGTGAGTGTTGGGTGGGAACAGCTCCCAGGAGGTTT
AATCACAGCCCCTCCATGCTCTCTAGCTGTTGCCATTGTGCAAGATGCATTTCCCTTCTGTGCAGCAGTTTCCCTGGCCA
CTAAATAGTGGGATTAGATAGAAGCCCTCCAAGGGCTTCCAGCTTGACATGATTCTTGATTCTGATCTGGCCCGATTCCT
GGATAATCGTGGGCAGGCCCATTCCTCTTCTTGTGCCTCATTTTCTTCTTTTGTAAAACAATGGCTGTACCATTTGCATC
TTAGGGTCATTGCAGATGTAAGTGTTGCTGTCCAGAGCCTGGGTGCAGGACCTAGATGTAGGATTCTGGTTCTGCTACTT
CCTCAGTGACATTGAATAGCTGACCTAATCTCTCTGGCTTTGGTTTCTTCATCTGTAAAAGAAGGATATTAGCATTAGCA
CCTCACGGGATTGTTACAAGAAAGCAATGAATTAACACATGTGAGCACGGAGAACAGTGCTTGGCATATGGTAAGCACTA
CGTACATTTTGCTATTCTTCTGATTCTTTCAGTGTTACTGATGTCGGCAAGTACTTGGCACAGGCTGGTTTAATAATCCC
TAGGCACTTCCACGTGGTGTCAATCCCTGATCACTGGGAGTCATCATGTGCCTTGACTCGGGGCCTGGCCCCCCCATCTC
TGTCTTGCAGGACAATGCCGTCTTCTGTCTCGTGGGGCATCCTCCTGCTGGCAGGCCTGTGCTGCCTGGTCCCTGTCTCC
CTGGCTGAGGATCCCCAGGGAGATGCTGCCCAGAAGACAGATACATCCCACCATGATCAGGATCACCCAACCTTCAACAA
GATCACCCCCAACCTGGCTGAGTTCGCCTTCAGCCTATACCGCCAGCTGGCACACCAGTCCAACAGCACCAATATCTTCT
TCTCCCCAGTGAGCATCGCTACAGCCTTTGCAATGCTCTCCCTGGGGACCAAGGCTGACACTCACGATGAAATCCTGGAG
GGCCTGAATTTCAACCTCACGGAGATTCCGGAGGCTCAGATCCATGAAGGCTTCCAGGAACTCCTCCGTACCCTCAACCA
GCCAGACAGCCAGCTCCAGCTGACCACCGGCAATGGCCTGTTCCTCAGCGAGGGCCTGAAGCTAGTGGATAAGTTTTTGG
AGGATGTTAAAAAGTTGTACCACTCAGAAGCCTTCACTGTCAACTTCGGGGACACCGAAGAGGCCAAGAAACAGATCAAC
GATTACGTGGAGAAGGGTACTCAAGGGAAAATTGTGGATTTGGTCAAGGAGCTTGACAGAGACACAGTTTTTGCTCTGGT
GAATTACATCTTCTTTAAAGGTAAGGTTGCTCAACCAGCCTGAGCTGTTCCCATAGAAACAAGCAAAAATATTCTCAAAC
CATCAGTTCTTGAACTCTCCTTGGCAATGCATTATGGGCCATAGCAATGCTTTTCAGCGTGGATTCTTCAGTTTTCTACA
CACAAACACTAAAATGTTTTCCATCATTGAGTAATTTGAGGAAATAATAGATTAAACTGTCAAAACTACTGACAGCTCTG
CAGAACTTTTCAGAGCCTTTAATGTCCTTGTGTATACTGTATATGTAGAATATATAATGCTTAGAACTATAGAACAAATT
GTAATACACTGCATAAAGGGATAGTTTCATGGAACATACTTTACACGACTCTAGTGTCCCAGAATCAGTATCAGTTTTGC
AATCTGAAAGACCTGGGTTCAAATCCTGCCTCTAACACAATTAGCTTTTGACAAAAACAATGCATTCTACCTCTTTGAGG
TGCTAATTTCTCATCTTAGCATGGACAAAATACCATTCTTGCTGTCAGGTTTTTTTAGGATTAAACAAATGACAAAGACT
GTGGGGATGGTGTGTGGCATACAGCAGGTGATGGACTCTTCTGTATCTCAGGCTGCCTTCCTGCCCCTGAGGGGTTAAAA
TGCCAGGGTCCTGGGGGCCCCAGGGCATTCTAAGCCAGCTCCCACTGTCCCAGGAAAACAGCATAGGGGAGGGGAGGTGG
GAGGCAAGGCCAGGGGCTGCTTCCTCCACTCTGAGGCTCCCTTGCTCTTGAGGCAAAGGAGGGCAGTGGAGAGCAGCCAG
GCTGCAGTCAGCACAGCTAAAGTCCTGGCTCTGCTGTGGCCTTAGTGGGGGCCCAGGTCCCTCTCCAGCCCCAGTCTCCT
CCTTCTGTCCAATGAGAAAGCTGGGATCAGGGGTCCCTGAGGCCCCTGTCCACTCTGCATGCCTCGATGGTGAAGCTCTG
TTGGTATGGCAGAGGGGAGGCTGCTCAGGCATCTGCATTTCCCCTGCCAATCTAGAGGATGAGGAAAGCTCTCAGGAATA
GTAAGCAGAATGTTTGCCCTGGATGAATAACTGAGCTGCCAATTAACAAGGGGCAGGGAGCCTTAGACAGAAGGTACCAA
ATATGCCTGATGCTCCAACATTTTATTTGTAATATCCAAGACACCCTCAAATAAACATATGATTCCAATAAAAATGCACA
GCCACGATGGCATCTCTTAGCCTGACATCGCCACGATGTAGAAATTCTGCATCTTCCTCTAGTTTTGAATTATCCCCACA
CAATCTTTTTCGGCAGCTTGGATGGTCAGTTTCAGCACCTTTTACAGATGATGAAGCTGAGCCTCGAGGGATGTGTGTCG
TCAAGGGGGCTCAGGGCTTCTCAGGGAGGGGACTCATGGTTTCTTTATTCTGCTACACTCTTCCAAACCTTCACTCACCC
CTGGTGATGCCCACCTTCCCCTCTCTCCAGGCAAATGGGAGAGACCCTTTGAAGTCAAGGACACCGAGGAAGAGGACTTC
CACGTGGACCAGGTGACCACCGTGAAGGTGCCTATGATGAAGCGTTTAGGCATGTTTAACATCCAGCACTGTAAGAAGCT
GTCCAGCTGGGTGCTGCTGATGAAATACCTGGGCAATGCCACCGCCATCTTCTTCCTGCCTGATGAGGGGAAACTACAGC
ACCTGGAAAATGAACTCACCCACGATATCATCACCAAGTTCCTGGAAAATGAAGACAGAAGGTGATTCCCCAACCTGAGG
GTGACCAAGAAGCTGCCCACACCTCTTAGCCATGTTGGGACTGAGGCCCATCAGGACTGGCCAGAGGGCTGAGGAGGGTG
AACCCCACATCCCTGGGTCACTGCTACTCTGTATAAACTTGGCTTCCAGAATGAGGCCACCACTGAGTTCAGGCAGCGCC
ATCCATGCTCCATGAGGAGGACAGTACCCAGGGGTGAGGAGGTAAAGGTCTCGTCCCTGGGGACTTCCCACTCCAGTGTG
GACACTGTCCCTTCCCAATATCCAGTGCCCAGGGCAGGGACAGCAGCACCACCACACGTTCTGGCAGAACCAAAAAGGAA
CAGATGGGCTTCCTGGCAAAGGCAGCAGTGGAGTGTGGAGTTCAAGGGTAGAATGTCCCTGGGGGGACGGGGGAAGAGCC
TGTGTGGCAAGGCCCAGAAAAGCAAGGTTCGGAATTGGAACAGCCAGGCCATGTTCGCAGAAGGCTTGCGTTTCTCTGTC
ACTTTATCGGTGCTGTTAGATTGGGTGTCCTGTAGTAAGTGATACTTAAACATGAGCCACACATTAGTGTATGTGTGTGC
ATTCGTGATTATGCCCATGCCCTGCTGATCTAGTTCGTTTTGTACACTGTAAAACCAAGATGAAAATACAAAAGGTGTCG
GGTTCATAATAGGAATCGAGGCTGGAATTTCTCTGTTCCATGCCAGCACCTCCTGAGGTCTCTGCTCCAGGGGTTGAGAA
AGAACAAAGAGGCTGAGAGGGTAACGGATCAGAGAGCCCAGAGCCAAGCTGCCCGCTCACACCAGACCCTGCTCAGGGTG
GCATTGTCTCCCCATGGAAAACCAGAGAGGAGCACTCAGCCTGGTGTGGTCACTCTTCTCTTATCCACTAAACGGTTGTC
ACTGGGCACTGCCACCAGCCCCGTGTTTCTCTGGGTGTAGGGCCCTGGGGATGTTACAGGCTGGGGGCCAGGTGACCCAA
CACTACAGGGCAAGATGAGACAGGCTTCCAGGACACCTAGAATATCAGAGGAGGTGGCATTTCAAGCTTTTGTGATTCAT
TCGATGTTAACATTCTTTGACTCAATGTAGAAGAGCTAAAAGTAGAACAAACCAAAGCCGAGTTCCCATCTTAGTGTGGG
TGGAGGACACAGGAGTAAGTGGCAGAAATAATCAGAAAAGAAAACACTTGCACTGTGGTGGGTCCCAGAAGAACAAGAGG
AATGCTGTGCCATGCCTTGAATTTCTTTTCTGCACGACAGGTCTGCCAGCTTACATTTACCCAAACTGTCCATTACTGGA
ACCTATGATCTGAAGAGCGTCCTGGGTCAACTGGGCATCACTAAGGTCTTCAGCAATGGGGCTGACCTCTCCGGGGTCAC
AGAGGAGGCACCCCTGAAGCTCTCCAAGGTGAGATCACCCTGACGACCTTGTTGCACCCTGGTATCTGTAGGGAAGAATG
TGTGGGGGCTGCAGCTCTGTCCTGAGGCTGAGGAAGGGGCCGAGGGAAACAAATGAAGACCCAGGCTGAGCTCCTGAAGA
TGCCCGTGATTCACTGACACGGGACGTGGTCAAACAGCAAAGCCAGGCAGGGGACTGCTGTGCAGCTGGCACTTTCGGGG
CCTCCCTTGAGGTTGTGTCACTGACCCTGAATTTCAACTTTGCCCAAGACCTTCTAGACATTGGGCCTTGATTTATCCAT
ACTGACACAGAAAGGTTTGGGCTAAGTTGTTTCAAAGGAATTTCTGACTCCTTCGATCTGTGAGATTTGGTGTCTGAATT
AATGAATGATTTCAGCTAAAGATGACACTTATTTTGGAAAACTAAAGGCGACCAATGAACAACTGCAGTTCCATGAATGG
CTGCATTATCTTGGGGTCTGGGCACTGTGAAGGTCACTGCCAGGGTCCGTGTCCTCAAGGAGCTTCAAGCCGTGTACTAG
AAAGGAGAGAGCCCTGGAGGCAGACGTGGAGTGACGATGCTCTTCCCTGTTCTGAGTTGTGGGTGCACCTGAGCAGGGGG
AGAGGCGCTTGTCAGGAAGATGGACAGAGGGGAGCCAGCCCCATCAGCCAAAGCCTTGAGGAGGAGCAAGGCCTATGTGA
CAGGGAGGGAGAGGATGTGCAGGGCCAGGGCCGTCCAGGGGGAGTGAGCGCTTCCTGGGAGGTGTCCACGTGAGCCTTGC
TCGAGGCCTGGGATCAGCCTTACAACGTGTCTCTGCTTCTCTCCCCTCCAGGCCGTGCATAAGGCTGTGCTGACCATCGA
CGAGAAAGGGACTGAAGCTGCTGGGGCCATGTTTTTAGAGGCCATACCCATGTCTATCCCCCCCGAGGTCAAGTTCAACA
AACCCTTTGTCTTCTTAATGATTGAACAAAATACCAAGTCTCCCCTCTTCATGGGAAAAGTGGTGAATCCCACCCAAAAA
TAACTGCCTCTCGCTCCTCAACCCCTCCCCTCCATCCCTGGCCCCCTCCCTGGATGACATTAAAGAAGGGTTGAGCTGGT
CCCTGCCTGCATGTGACTGTAAATCCCTCCCATGTTTTCTCTGAGTCTCCCTTTGCCTGCTGAGGCTGTATGTGGGCTCC
AGGTAACAGTGCTGTCTTCGGGCCCCCTGAACTGTGTTCATGGAGCATCTGGCTGGGTAGGCACATGCTGGGCTTGAATC
CAGGGGGGACTGAATCCTCAGCTTACGGACCTGGGCCCATCTGTTTCTGGAGGGCTCCAGTCTTCCTTGTCCTGTCTTGG
AGTCCCCAAGAAGGAATCACAGGGGAGGAACCAGATACCAGCCATGACCCCAGGCTCCACCAAGCATCTTCATGTCCCCC
TGCTCATCCCCCACTCCCCCCCACCCAGAGTTGCTCATCCTGCCAGGGCTGGCTGTGCCCACCCCAAGGCTGCCCTCCTG
GGGGCCCCAGAACTGCCTGATCGTGCCGTGGCCCAGTTTTGTGGCATCTGCAGCAACACAAGAGAGAGGACAATGTCCTC
CTCTTGACCCGCTGTCACCTAACCAGACTCGGGCCCTGCACCTCTCAGGCACTTCTGGAAAATGACTGAGGCAGATTCTT
CCTGAAGCCCATTCTCCATGGGGCAACAAGGACACCTATTCTGTCCTTGTCCTTCCATCGCTGCCCCAGAAAGCCTCACA
TATCTCCGTTTAGAATCAGGTCCCTTCTCCCCAGATGAAGAGGAGGGTCTCTGCTTTGTTTTCTCTATCTCCTCCTCAGA
CTTGACCAGGCCCAGCAGGCCCCAGAAGACCATTACCCTATATCCCTTCTCCTCCCTAGTCACATGGCCATAGGCCTGCT
GATGGCTCAGGAAGGCCATTGCAAGGACTCCTCAGCTATGGGAGAGGAAGCACATCACCCATTGACCCCCGCAACCCCTC
CCTTTCCTCCTCTGAGTCCCGACTGGGGCCACATGCAGCCTGACTTCTTTGTGCCTGTTGCTGTCCCTGCAGTCTTCAGA
GGGCCACCGCAGCTCCAGTGCCACGGCAGGAGGCTGTTCCTGAATAGCCCCTGTGGTAAGGGCCAGGAGAGTCCTTCCAT
CCTCCAAGGCCCTGCTAAAGGACACAGCAGCCAGGAAGTCCCCTGGGCCCCTAGCTGAAGGACAGCCTGCTCCCTCCGTC
TCTACCAGGAATGGCCTTGTCCTATGGAAGGCACTGCCCCATCCCAAACTAATCTAGGAATCACTGTCTAACCACTCACT
GTCATGAATGTGTACTTAAAGGATGAGGTTGAGTCATACCAAATAGTGATTTCGATAGTTCAAAATGGTGAAATTAGCAA
TTCTACATGATTCAGTCTAATCAATGGATACCGACTGTTTCCCACACAAGTCTCCTGTTCTCTTAAGCTTACTCACTGAC
AGCCTTTCACTCTCCACAAATACATTAAAGATATGGCCATCACCAAGCCCCCTAGGATGACACCAGACCTGAGAGTCTGA
AGACCTGGATCCAAGTTCTGACTTTTCCCCCTGACAGCTGTGTGACCTTCGTGAAGTCGCCAAACCTCTCTGAGCCCCAG
TCATTGCTAGTAAGACCTGCCTTTGAGTTGGTATGATGTTCAAGTTAGATAACAAAATGTTTATACCCATTAGAACAGAG
AATAAATAGAACTACATTTCTTGCAC
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Primary source |
RefSeq : NM_000295.4 (GI:189163524)
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Name |
Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (SERPINA1), transcript variant 1
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Type of transcript |
mRNA
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Organism |
Homo sapiens
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Length |
3220 nt
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Map |
14q32.1
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Location |
Chromosome 14 (NC_000014.8) strand : -
94843083...94844976 | 94845800...94845947 | 94847207...94847477 | 94848928...94849577 |
94854896...94855152 |
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Exon(s) |
Start |
End |
Length |
is coding |
Exon 2c
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1
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257
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257
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1
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Exon 3
|
258
|
907
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650
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1
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Exon 4
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908
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1178
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271
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1
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Exon 5
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1179
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1326
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148
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1
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Exon 6
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1327
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3220
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1894
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1
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ID |
Class |
Location |
Mutation |
Length |
is synonymous |
Source |
rs55967149
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SNP
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39
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a/g
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1
|
?
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dbSNP
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rs55973910
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SNP
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54
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c/t
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1
|
?
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dbSNP
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rs55961721
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SNP
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74
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a/g
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1
|
?
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dbSNP
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Primary source |
NCBI : CCDS9925
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Nucleotide |
SERPINA1, mRNA isoform 1[NM_000295.4] : 262...1518
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Length |
1257
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Location |
Chromosome 14 (NC_000014.8) strand : -
94844785...94844976 | 94845800...94845947 | 94847207...94847477 | 94848928...94849573 |
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Start codon |
1
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Translation |
NP_000286.3 |
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1 |
ACAATGACTC |
CTTTCGGTAA |
GTGCAGTGGA |
AGCTGTACAC |
TGCCCAGGCA |
AAGCGTCCGG |
GCAGCGTAGG |
CGGGCGACTC |
|
81 |
AGATCCCAGC |
CAGTGGACTT |
AGCCCCTGTT |
TGCTCCTCCG |
ATAACTGGGG |
TGACCTTGGT |
TAATATTCAC |
CAGCAGCCTC |
|
161 |
CCCCGTTGCC |
CCTCTGGATC |
CACTGCTTAA |
ATACGGACGA |
GGACAGGGCC |
CTGTCTCCTC |
AGCTTCAGGC |
ACCACCACTG |
|
241 |
ACCTGGGACA |
GTGAATCGAC |
AATGCCGTCT |
TCTGTCTCGT |
GGGGCATCCT |
CCTGCTGGCA |
GGCCTGTGCT |
GCCTGGTCCC |
|
321 |
TGTCTCCCTG |
GCTGAGGATC |
CCCAGGGAGA |
TGCTGCCCAG |
AAGACAGATA |
CATCCCACCA |
TGATCAGGAT |
CACCCAACCT |
|
401 |
TCAACAAGAT |
CACCCCCAAC |
CTGGCTGAGT |
TCGCCTTCAG |
CCTATACCGC |
CAGCTGGCAC |
ACCAGTCCAA |
CAGCACCAAT |
|
481 |
ATCTTCTTCT |
CCCCAGTGAG |
CATCGCTACA |
GCCTTTGCAA |
TGCTCTCCCT |
GGGGACCAAG |
GCTGACACTC |
ACGATGAAAT |
|
561 |
CCTGGAGGGC |
CTGAATTTCA |
ACCTCACGGA |
GATTCCGGAG |
GCTCAGATCC |
ATGAAGGCTT |
CCAGGAACTC |
CTCCGTACCC |
|
641 |
TCAACCAGCC |
AGACAGCCAG |
CTCCAGCTGA |
CCACCGGCAA |
TGGCCTGTTC |
CTCAGCGAGG |
GCCTGAAGCT |
AGTGGATAAG |
|
721 |
TTTTTGGAGG |
ATGTTAAAAA |
GTTGTACCAC |
TCAGAAGCCT |
TCACTGTCAA |
CTTCGGGGAC |
ACCGAAGAGG |
CCAAGAAACA |
|
801 |
GATCAACGAT |
TACGTGGAGA |
AGGGTACTCA |
AGGGAAAATT |
GTGGATTTGG |
TCAAGGAGCT |
TGACAGAGAC |
ACAGTTTTTG |
|
881 |
CTCTGGTGAA |
TTACATCTTC |
TTTAAAGGCA |
AATGGGAGAG |
ACCCTTTGAA |
GTCAAGGACA |
CCGAGGAAGA |
GGACTTCCAC |
|
961 |
GTGGACCAGG |
TGACCACCGT |
GAAGGTGCCT |
ATGATGAAGC |
GTTTAGGCAT |
GTTTAACATC |
CAGCACTGTA |
AGAAGCTGTC |
|
1041 |
CAGCTGGGTG |
CTGCTGATGA |
AATACCTGGG |
CAATGCCACC |
GCCATCTTCT |
TCCTGCCTGA |
TGAGGGGAAA |
CTACAGCACC |
|
1121 |
TGGAAAATGA |
ACTCACCCAC |
GATATCATCA |
CCAAGTTCCT |
GGAAAATGAA |
GACAGAAGGT |
CTGCCAGCTT |
ACATTTACCC |
|
1201 |
AAACTGTCCA |
TTACTGGAAC |
CTATGATCTG |
AAGAGCGTCC |
TGGGTCAACT |
GGGCATCACT |
AAGGTCTTCA |
GCAATGGGGC |
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1281 |
TGACCTCTCC |
GGGGTCACAG |
AGGAGGCACC |
CCTGAAGCTC |
TCCAAGGCCG |
TGCATAAGGC |
TGTGCTGACC |
ATCGACGAGA |
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1361 |
AAGGGACTGA |
AGCTGCTGGG |
GCCATGTTTT |
TAGAGGCCAT |
ACCCATGTCT |
ATCCCCCCCG |
AGGTCAAGTT |
CAACAAACCC |
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1441 |
TTTGTCTTCT |
TAATGATTGA |
ACAAAATACC |
AAGTCTCCCC |
TCTTCATGGG |
AAAAGTGGTG |
AATCCCACCC |
AAAAATAACT |
|
1521 |
GCCTCTCGCT |
CCTCAACCCC |
TCCCCTCCAT |
CCCTGGCCCC |
CTCCCTGGAT |
GACATTAAAG |
AAGGGTTGAG |
CTGGTCCCTG |
|
1601 |
CCTGCATGTG |
ACTGTAAATC |
CCTCCCATGT |
TTTCTCTGAG |
TCTCCCTTTG |
CCTGCTGAGG |
CTGTATGTGG |
GCTCCAGGTA |
|
1681 |
ACAGTGCTGT |
CTTCGGGCCC |
CCTGAACTGT |
GTTCATGGAG |
CATCTGGCTG |
GGTAGGCACA |
TGCTGGGCTT |
GAATCCAGGG |
|
1761 |
GGGACTGAAT |
CCTCAGCTTA |
CGGACCTGGG |
CCCATCTGTT |
TCTGGAGGGC |
TCCAGTCTTC |
CTTGTCCTGT |
CTTGGAGTCC |
|
1841 |
CCAAGAAGGA |
ATCACAGGGG |
AGGAACCAGA |
TACCAGCCAT |
GACCCCAGGC |
TCCACCAAGC |
ATCTTCATGT |
CCCCCTGCTC |
|
1921 |
ATCCCCCACT |
CCCCCCCACC |
CAGAGTTGCT |
CATCCTGCCA |
GGGCTGGCTG |
TGCCCACCCC |
AAGGCTGCCC |
TCCTGGGGGC |
|
2001 |
CCCAGAACTG |
CCTGATCGTG |
CCGTGGCCCA |
GTTTTGTGGC |
ATCTGCAGCA |
ACACAAGAGA |
GAGGACAATG |
TCCTCCTCTT |
|
2081 |
GACCCGCTGT |
CACCTAACCA |
GACTCGGGCC |
CTGCACCTCT |
CAGGCACTTC |
TGGAAAATGA |
CTGAGGCAGA |
TTCTTCCTGA |
|
2161 |
AGCCCATTCT |
CCATGGGGCA |
ACAAGGACAC |
CTATTCTGTC |
CTTGTCCTTC |
CATCGCTGCC |
CCAGAAAGCC |
TCACATATCT |
|
2241 |
CCGTTTAGAA |
TCAGGTCCCT |
TCTCCCCAGA |
TGAAGAGGAG |
GGTCTCTGCT |
TTGTTTTCTC |
TATCTCCTCC |
TCAGACTTGA |
|
2321 |
CCAGGCCCAG |
CAGGCCCCAG |
AAGACCATTA |
CCCTATATCC |
CTTCTCCTCC |
CTAGTCACAT |
GGCCATAGGC |
CTGCTGATGG |
|
2401 |
CTCAGGAAGG |
CCATTGCAAG |
GACTCCTCAG |
CTATGGGAGA |
GGAAGCACAT |
CACCCATTGA |
CCCCCGCAAC |
CCCTCCCTTT |
|
2481 |
CCTCCTCTGA |
GTCCCGACTG |
GGGCCACATG |
CAGCCTGACT |
TCTTTGTGCC |
TGTTGCTGTC |
CCTGCAGTCT |
TCAGAGGGCC |
|
2561 |
ACCGCAGCTC |
CAGTGCCACG |
GCAGGAGGCT |
GTTCCTGAAT |
AGCCCCTGTG |
GTAAGGGCCA |
GGAGAGTCCT |
TCCATCCTCC |
|
2641 |
AAGGCCCTGC |
TAAAGGACAC |
AGCAGCCAGG |
AAGTCCCCTG |
GGCCCCTAGC |
TGAAGGACAG |
CCTGCTCCCT |
CCGTCTCTAC |
|
2721 |
CAGGAATGGC |
CTTGTCCTAT |
GGAAGGCACT |
GCCCCATCCC |
AAACTAATCT |
AGGAATCACT |
GTCTAACCAC |
TCACTGTCAT |
|
2801 |
GAATGTGTAC |
TTAAAGGATG |
AGGTTGAGTC |
ATACCAAATA |
GTGATTTCGA |
TAGTTCAAAA |
TGGTGAAATT |
AGCAATTCTA |
|
2881 |
CATGATTCAG |
TCTAATCAAT |
GGATACCGAC |
TGTTTCCCAC |
ACAAGTCTCC |
TGTTCTCTTA |
AGCTTACTCA |
CTGACAGCCT |
|
2961 |
TTCACTCTCC |
ACAAATACAT |
TAAAGATATG |
GCCATCACCA |
AGCCCCCTAG |
GATGACACCA |
GACCTGAGAG |
TCTGAAGACC |
|
3041 |
TGGATCCAAG |
TTCTGACTTT |
TCCCCCTGAC |
AGCTGTGTGA |
CCTTCGTGAA |
GTCGCCAAAC |
CTCTCTGAGC |
CCCAGTCATT |
|
3121 |
GCTAGTAAGA |
CCTGCCTTTG |
AGTTGGTATG |
ATGTTCAAGT |
TAGATAACAA |
AATGTTTATA |
CCCATTAGAA |
CAGAGAATAA |
|
3201 |
ATAGAACTAC |
ATTTCTTGCA |
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>gi|189163524|ref|NM_000295.4|Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (SERPINA1), transcript variant 1
ACAATGACTCCTTTCGGTAAGTGCAGTGGAAGCTGTACACTGCCCAGGCAAAGCGTCCGGGCAGCGTAGGCGGGCGACTC
AGATCCCAGCCAGTGGACTTAGCCCCTGTTTGCTCCTCCGATAACTGGGGTGACCTTGGTTAATATTCACCAGCAGCCTC
CCCCGTTGCCCCTCTGGATCCACTGCTTAAATACGGACGAGGACAGGGCCCTGTCTCCTCAGCTTCAGGCACCACCACTG
ACCTGGGACAGTGAATCGACAATGCCGTCTTCTGTCTCGTGGGGCATCCTCCTGCTGGCAGGCCTGTGCTGCCTGGTCCC
TGTCTCCCTGGCTGAGGATCCCCAGGGAGATGCTGCCCAGAAGACAGATACATCCCACCATGATCAGGATCACCCAACCT
TCAACAAGATCACCCCCAACCTGGCTGAGTTCGCCTTCAGCCTATACCGCCAGCTGGCACACCAGTCCAACAGCACCAAT
ATCTTCTTCTCCCCAGTGAGCATCGCTACAGCCTTTGCAATGCTCTCCCTGGGGACCAAGGCTGACACTCACGATGAAAT
CCTGGAGGGCCTGAATTTCAACCTCACGGAGATTCCGGAGGCTCAGATCCATGAAGGCTTCCAGGAACTCCTCCGTACCC
TCAACCAGCCAGACAGCCAGCTCCAGCTGACCACCGGCAATGGCCTGTTCCTCAGCGAGGGCCTGAAGCTAGTGGATAAG
TTTTTGGAGGATGTTAAAAAGTTGTACCACTCAGAAGCCTTCACTGTCAACTTCGGGGACACCGAAGAGGCCAAGAAACA
GATCAACGATTACGTGGAGAAGGGTACTCAAGGGAAAATTGTGGATTTGGTCAAGGAGCTTGACAGAGACACAGTTTTTG
CTCTGGTGAATTACATCTTCTTTAAAGGCAAATGGGAGAGACCCTTTGAAGTCAAGGACACCGAGGAAGAGGACTTCCAC
GTGGACCAGGTGACCACCGTGAAGGTGCCTATGATGAAGCGTTTAGGCATGTTTAACATCCAGCACTGTAAGAAGCTGTC
CAGCTGGGTGCTGCTGATGAAATACCTGGGCAATGCCACCGCCATCTTCTTCCTGCCTGATGAGGGGAAACTACAGCACC
TGGAAAATGAACTCACCCACGATATCATCACCAAGTTCCTGGAAAATGAAGACAGAAGGTCTGCCAGCTTACATTTACCC
AAACTGTCCATTACTGGAACCTATGATCTGAAGAGCGTCCTGGGTCAACTGGGCATCACTAAGGTCTTCAGCAATGGGGC
TGACCTCTCCGGGGTCACAGAGGAGGCACCCCTGAAGCTCTCCAAGGCCGTGCATAAGGCTGTGCTGACCATCGACGAGA
AAGGGACTGAAGCTGCTGGGGCCATGTTTTTAGAGGCCATACCCATGTCTATCCCCCCCGAGGTCAAGTTCAACAAACCC
TTTGTCTTCTTAATGATTGAACAAAATACCAAGTCTCCCCTCTTCATGGGAAAAGTGGTGAATCCCACCCAAAAATAACT
GCCTCTCGCTCCTCAACCCCTCCCCTCCATCCCTGGCCCCCTCCCTGGATGACATTAAAGAAGGGTTGAGCTGGTCCCTG
CCTGCATGTGACTGTAAATCCCTCCCATGTTTTCTCTGAGTCTCCCTTTGCCTGCTGAGGCTGTATGTGGGCTCCAGGTA
ACAGTGCTGTCTTCGGGCCCCCTGAACTGTGTTCATGGAGCATCTGGCTGGGTAGGCACATGCTGGGCTTGAATCCAGGG
GGGACTGAATCCTCAGCTTACGGACCTGGGCCCATCTGTTTCTGGAGGGCTCCAGTCTTCCTTGTCCTGTCTTGGAGTCC
CCAAGAAGGAATCACAGGGGAGGAACCAGATACCAGCCATGACCCCAGGCTCCACCAAGCATCTTCATGTCCCCCTGCTC
ATCCCCCACTCCCCCCCACCCAGAGTTGCTCATCCTGCCAGGGCTGGCTGTGCCCACCCCAAGGCTGCCCTCCTGGGGGC
CCCAGAACTGCCTGATCGTGCCGTGGCCCAGTTTTGTGGCATCTGCAGCAACACAAGAGAGAGGACAATGTCCTCCTCTT
GACCCGCTGTCACCTAACCAGACTCGGGCCCTGCACCTCTCAGGCACTTCTGGAAAATGACTGAGGCAGATTCTTCCTGA
AGCCCATTCTCCATGGGGCAACAAGGACACCTATTCTGTCCTTGTCCTTCCATCGCTGCCCCAGAAAGCCTCACATATCT
CCGTTTAGAATCAGGTCCCTTCTCCCCAGATGAAGAGGAGGGTCTCTGCTTTGTTTTCTCTATCTCCTCCTCAGACTTGA
CCAGGCCCAGCAGGCCCCAGAAGACCATTACCCTATATCCCTTCTCCTCCCTAGTCACATGGCCATAGGCCTGCTGATGG
CTCAGGAAGGCCATTGCAAGGACTCCTCAGCTATGGGAGAGGAAGCACATCACCCATTGACCCCCGCAACCCCTCCCTTT
CCTCCTCTGAGTCCCGACTGGGGCCACATGCAGCCTGACTTCTTTGTGCCTGTTGCTGTCCCTGCAGTCTTCAGAGGGCC
ACCGCAGCTCCAGTGCCACGGCAGGAGGCTGTTCCTGAATAGCCCCTGTGGTAAGGGCCAGGAGAGTCCTTCCATCCTCC
AAGGCCCTGCTAAAGGACACAGCAGCCAGGAAGTCCCCTGGGCCCCTAGCTGAAGGACAGCCTGCTCCCTCCGTCTCTAC
CAGGAATGGCCTTGTCCTATGGAAGGCACTGCCCCATCCCAAACTAATCTAGGAATCACTGTCTAACCACTCACTGTCAT
GAATGTGTACTTAAAGGATGAGGTTGAGTCATACCAAATAGTGATTTCGATAGTTCAAAATGGTGAAATTAGCAATTCTA
CATGATTCAGTCTAATCAATGGATACCGACTGTTTCCCACACAAGTCTCCTGTTCTCTTAAGCTTACTCACTGACAGCCT
TTCACTCTCCACAAATACATTAAAGATATGGCCATCACCAAGCCCCCTAGGATGACACCAGACCTGAGAGTCTGAAGACC
TGGATCCAAGTTCTGACTTTTCCCCCTGACAGCTGTGTGACCTTCGTGAAGTCGCCAAACCTCTCTGAGCCCCAGTCATT
GCTAGTAAGACCTGCCTTTGAGTTGGTATGATGTTCAAGTTAGATAACAAAATGTTTATACCCATTAGAACAGAGAATAA
ATAGAACTACATTTCTTGCA
|
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| |
|
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|
|
|
|
|
|
|
|
|
|
|
|
Primary source |
RefSeq : NM_001127706.1 (GI:189163539)
|
Name |
Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (SERPINA1), transcript variant 10
|
Type of transcript |
mRNA
|
Organism |
Homo sapiens
|
Length |
3303 nt
|
Map |
14q32.1
|
Location |
Chromosome 14 (NC_000014.8) strand : -
94843083...94844976 | 94845800...94845947 | 94847207...94847477 | 94848928...94849577 |
94854896...94854999 | 94856793...94857028 |
|
|
|
|
|
|
|
|
|
|
|
|
|
Exon(s) |
Start |
End |
Length |
is coding |
Exon 1a
|
1
|
236
|
236
|
1
|
Exon 2d
|
237
|
340
|
104
|
1
|
Exon 3
|
341
|
990
|
650
|
1
|
Exon 4
|
991
|
1261
|
271
|
1
|
Exon 5
|
1262
|
1409
|
148
|
1
|
Exon 6
|
1410
|
3303
|
1894
|
1
|
|
|
|
|
|
|
|
|
|
|
|
|
ID |
Class |
Location |
Mutation |
Length |
is synonymous |
Source |
|
|
|
|
|
|
|
|
|
|
|
|
Primary source |
NCBI : CCDS9925
|
Nucleotide |
SERPINA1, mRNA isoform 10[NM_001127706.1] : 345...1601
|
Length |
1257
|
Location |
Chromosome 14 (NC_000014.8) strand : -
94844785...94844976 | 94845800...94845947 | 94847207...94847477 | 94848928...94849573 |
|
Start codon |
1
|
Translation |
NP_001121178.1 |
|
|
|
|
|
|
|
|
|
|
|
|
1 |
TGGGCAGGAA |
CTGGGCACTG |
TGCCCAGGGC |
ATGCACTGCC |
TCCACGCAGC |
AACCCTCAGA |
GTCCTGAGCT |
GAACCAAGAA |
|
81 |
GGAGGAGGGG |
GTCGGGCCTC |
CGAGGAAGGC |
CTAGCCGCTG |
CTGCTGCCAG |
GAATTCCAGG |
TTGGAGGGGC |
GGCAACCTCC |
|
161 |
TGCCAGCCTT |
CAGGCCACTC |
TCCTGTGCCT |
GCCAGAAGAG |
ACAGAGCTTG |
AGGAGAGCTT |
GAGGAGAGCA |
GGAAAGCAGC |
|
241 |
CTCCCCCGTT |
GCCCCTCTGG |
ATCCACTGCT |
TAAATACGGA |
CGAGGACAGG |
GCCCTGTCTC |
CTCAGCTTCA |
GGCACCACCA |
|
321 |
CTGACCTGGG |
ACAGTGAATC |
GACAATGCCG |
TCTTCTGTCT |
CGTGGGGCAT |
CCTCCTGCTG |
GCAGGCCTGT |
GCTGCCTGGT |
|
401 |
CCCTGTCTCC |
CTGGCTGAGG |
ATCCCCAGGG |
AGATGCTGCC |
CAGAAGACAG |
ATACATCCCA |
CCATGATCAG |
GATCACCCAA |
|
481 |
CCTTCAACAA |
GATCACCCCC |
AACCTGGCTG |
AGTTCGCCTT |
CAGCCTATAC |
CGCCAGCTGG |
CACACCAGTC |
CAACAGCACC |
|
561 |
AATATCTTCT |
TCTCCCCAGT |
GAGCATCGCT |
ACAGCCTTTG |
CAATGCTCTC |
CCTGGGGACC |
AAGGCTGACA |
CTCACGATGA |
|
641 |
AATCCTGGAG |
GGCCTGAATT |
TCAACCTCAC |
GGAGATTCCG |
GAGGCTCAGA |
TCCATGAAGG |
CTTCCAGGAA |
CTCCTCCGTA |
|
721 |
CCCTCAACCA |
GCCAGACAGC |
CAGCTCCAGC |
TGACCACCGG |
CAATGGCCTG |
TTCCTCAGCG |
AGGGCCTGAA |
GCTAGTGGAT |
|
801 |
AAGTTTTTGG |
AGGATGTTAA |
AAAGTTGTAC |
CACTCAGAAG |
CCTTCACTGT |
CAACTTCGGG |
GACACCGAAG |
AGGCCAAGAA |
|
881 |
ACAGATCAAC |
GATTACGTGG |
AGAAGGGTAC |
TCAAGGGAAA |
ATTGTGGATT |
TGGTCAAGGA |
GCTTGACAGA |
GACACAGTTT |
|
961 |
TTGCTCTGGT |
GAATTACATC |
TTCTTTAAAG |
GCAAATGGGA |
GAGACCCTTT |
GAAGTCAAGG |
ACACCGAGGA |
AGAGGACTTC |
|
1041 |
CACGTGGACC |
AGGTGACCAC |
CGTGAAGGTG |
CCTATGATGA |
AGCGTTTAGG |
CATGTTTAAC |
ATCCAGCACT |
GTAAGAAGCT |
|
1121 |
GTCCAGCTGG |
GTGCTGCTGA |
TGAAATACCT |
GGGCAATGCC |
ACCGCCATCT |
TCTTCCTGCC |
TGATGAGGGG |
AAACTACAGC |
|
1201 |
ACCTGGAAAA |
TGAACTCACC |
CACGATATCA |
TCACCAAGTT |
CCTGGAAAAT |
GAAGACAGAA |
GGTCTGCCAG |
CTTACATTTA |
|
1281 |
CCCAAACTGT |
CCATTACTGG |
AACCTATGAT |
CTGAAGAGCG |
TCCTGGGTCA |
ACTGGGCATC |
ACTAAGGTCT |
TCAGCAATGG |
|
1361 |
GGCTGACCTC |
TCCGGGGTCA |
CAGAGGAGGC |
ACCCCTGAAG |
CTCTCCAAGG |
CCGTGCATAA |
GGCTGTGCTG |
ACCATCGACG |
|
1441 |
AGAAAGGGAC |
TGAAGCTGCT |
GGGGCCATGT |
TTTTAGAGGC |
CATACCCATG |
TCTATCCCCC |
CCGAGGTCAA |
GTTCAACAAA |
|
1521 |
CCCTTTGTCT |
TCTTAATGAT |
TGAACAAAAT |
ACCAAGTCTC |
CCCTCTTCAT |
GGGAAAAGTG |
GTGAATCCCA |
CCCAAAAATA |
|
1601 |
ACTGCCTCTC |
GCTCCTCAAC |
CCCTCCCCTC |
CATCCCTGGC |
CCCCTCCCTG |
GATGACATTA |
AAGAAGGGTT |
GAGCTGGTCC |
|
1681 |
CTGCCTGCAT |
GTGACTGTAA |
ATCCCTCCCA |
TGTTTTCTCT |
GAGTCTCCCT |
TTGCCTGCTG |
AGGCTGTATG |
TGGGCTCCAG |
|
1761 |
GTAACAGTGC |
TGTCTTCGGG |
CCCCCTGAAC |
TGTGTTCATG |
GAGCATCTGG |
CTGGGTAGGC |
ACATGCTGGG |
CTTGAATCCA |
|
1841 |
GGGGGGACTG |
AATCCTCAGC |
TTACGGACCT |
GGGCCCATCT |
GTTTCTGGAG |
GGCTCCAGTC |
TTCCTTGTCC |
TGTCTTGGAG |
|
1921 |
TCCCCAAGAA |
GGAATCACAG |
GGGAGGAACC |
AGATACCAGC |
CATGACCCCA |
GGCTCCACCA |
AGCATCTTCA |
TGTCCCCCTG |
|
2001 |
CTCATCCCCC |
ACTCCCCCCC |
ACCCAGAGTT |
GCTCATCCTG |
CCAGGGCTGG |
CTGTGCCCAC |
CCCAAGGCTG |
CCCTCCTGGG |
|
2081 |
GGCCCCAGAA |
CTGCCTGATC |
GTGCCGTGGC |
CCAGTTTTGT |
GGCATCTGCA |
GCAACACAAG |
AGAGAGGACA |
ATGTCCTCCT |
|
2161 |
CTTGACCCGC |
TGTCACCTAA |
CCAGACTCGG |
GCCCTGCACC |
TCTCAGGCAC |
TTCTGGAAAA |
TGACTGAGGC |
AGATTCTTCC |
|
2241 |
TGAAGCCCAT |
TCTCCATGGG |
GCAACAAGGA |
CACCTATTCT |
GTCCTTGTCC |
TTCCATCGCT |
GCCCCAGAAA |
GCCTCACATA |
|
2321 |
TCTCCGTTTA |
GAATCAGGTC |
CCTTCTCCCC |
AGATGAAGAG |
GAGGGTCTCT |
GCTTTGTTTT |
CTCTATCTCC |
TCCTCAGACT |
|
2401 |
TGACCAGGCC |
CAGCAGGCCC |
CAGAAGACCA |
TTACCCTATA |
TCCCTTCTCC |
TCCCTAGTCA |
CATGGCCATA |
GGCCTGCTGA |
|
2481 |
TGGCTCAGGA |
AGGCCATTGC |
AAGGACTCCT |
CAGCTATGGG |
AGAGGAAGCA |
CATCACCCAT |
TGACCCCCGC |
AACCCCTCCC |
|
2561 |
TTTCCTCCTC |
TGAGTCCCGA |
CTGGGGCCAC |
ATGCAGCCTG |
ACTTCTTTGT |
GCCTGTTGCT |
GTCCCTGCAG |
TCTTCAGAGG |
|
2641 |
GCCACCGCAG |
CTCCAGTGCC |
ACGGCAGGAG |
GCTGTTCCTG |
AATAGCCCCT |
GTGGTAAGGG |
CCAGGAGAGT |
CCTTCCATCC |
|
2721 |
TCCAAGGCCC |
TGCTAAAGGA |
CACAGCAGCC |
AGGAAGTCCC |
CTGGGCCCCT |
AGCTGAAGGA |
CAGCCTGCTC |
CCTCCGTCTC |
|
2801 |
TACCAGGAAT |
GGCCTTGTCC |
TATGGAAGGC |
ACTGCCCCAT |
CCCAAACTAA |
TCTAGGAATC |
ACTGTCTAAC |
CACTCACTGT |
|
2881 |
CATGAATGTG |
TACTTAAAGG |
ATGAGGTTGA |
GTCATACCAA |
ATAGTGATTT |
CGATAGTTCA |
AAATGGTGAA |
ATTAGCAATT |
|
2961 |
CTACATGATT |
CAGTCTAATC |
AATGGATACC |
GACTGTTTCC |
CACACAAGTC |
TCCTGTTCTC |
TTAAGCTTAC |
TCACTGACAG |
|
3041 |
CCTTTCACTC |
TCCACAAATA |
CATTAAAGAT |
ATGGCCATCA |
CCAAGCCCCC |
TAGGATGACA |
CCAGACCTGA |
GAGTCTGAAG |
|
3121 |
ACCTGGATCC |
AAGTTCTGAC |
TTTTCCCCCT |
GACAGCTGTG |
TGACCTTCGT |
GAAGTCGCCA |
AACCTCTCTG |
AGCCCCAGTC |
|
3201 |
ATTGCTAGTA |
AGACCTGCCT |
TTGAGTTGGT |
ATGATGTTCA |
AGTTAGATAA |
CAAAATGTTT |
ATACCCATTA |
GAACAGAGAA |
|
3281 |
TAAATAGAAC |
TACATTTCTT |
GCA |
|
|
|
|
|
|
|
|
|
|
|
|
>gi|189163539|ref|NM_001127706.1|Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (SERPINA1), transcript variant 10
TGGGCAGGAACTGGGCACTGTGCCCAGGGCATGCACTGCCTCCACGCAGCAACCCTCAGAGTCCTGAGCTGAACCAAGAA
GGAGGAGGGGGTCGGGCCTCCGAGGAAGGCCTAGCCGCTGCTGCTGCCAGGAATTCCAGGTTGGAGGGGCGGCAACCTCC
TGCCAGCCTTCAGGCCACTCTCCTGTGCCTGCCAGAAGAGACAGAGCTTGAGGAGAGCTTGAGGAGAGCAGGAAAGCAGC
CTCCCCCGTTGCCCCTCTGGATCCACTGCTTAAATACGGACGAGGACAGGGCCCTGTCTCCTCAGCTTCAGGCACCACCA
CTGACCTGGGACAGTGAATCGACAATGCCGTCTTCTGTCTCGTGGGGCATCCTCCTGCTGGCAGGCCTGTGCTGCCTGGT
CCCTGTCTCCCTGGCTGAGGATCCCCAGGGAGATGCTGCCCAGAAGACAGATACATCCCACCATGATCAGGATCACCCAA
CCTTCAACAAGATCACCCCCAACCTGGCTGAGTTCGCCTTCAGCCTATACCGCCAGCTGGCACACCAGTCCAACAGCACC
AATATCTTCTTCTCCCCAGTGAGCATCGCTACAGCCTTTGCAATGCTCTCCCTGGGGACCAAGGCTGACACTCACGATGA
AATCCTGGAGGGCCTGAATTTCAACCTCACGGAGATTCCGGAGGCTCAGATCCATGAAGGCTTCCAGGAACTCCTCCGTA
CCCTCAACCAGCCAGACAGCCAGCTCCAGCTGACCACCGGCAATGGCCTGTTCCTCAGCGAGGGCCTGAAGCTAGTGGAT
AAGTTTTTGGAGGATGTTAAAAAGTTGTACCACTCAGAAGCCTTCACTGTCAACTTCGGGGACACCGAAGAGGCCAAGAA
ACAGATCAACGATTACGTGGAGAAGGGTACTCAAGGGAAAATTGTGGATTTGGTCAAGGAGCTTGACAGAGACACAGTTT
TTGCTCTGGTGAATTACATCTTCTTTAAAGGCAAATGGGAGAGACCCTTTGAAGTCAAGGACACCGAGGAAGAGGACTTC
CACGTGGACCAGGTGACCACCGTGAAGGTGCCTATGATGAAGCGTTTAGGCATGTTTAACATCCAGCACTGTAAGAAGCT
GTCCAGCTGGGTGCTGCTGATGAAATACCTGGGCAATGCCACCGCCATCTTCTTCCTGCCTGATGAGGGGAAACTACAGC
ACCTGGAAAATGAACTCACCCACGATATCATCACCAAGTTCCTGGAAAATGAAGACAGAAGGTCTGCCAGCTTACATTTA
CCCAAACTGTCCATTACTGGAACCTATGATCTGAAGAGCGTCCTGGGTCAACTGGGCATCACTAAGGTCTTCAGCAATGG
GGCTGACCTCTCCGGGGTCACAGAGGAGGCACCCCTGAAGCTCTCCAAGGCCGTGCATAAGGCTGTGCTGACCATCGACG
AGAAAGGGACTGAAGCTGCTGGGGCCATGTTTTTAGAGGCCATACCCATGTCTATCCCCCCCGAGGTCAAGTTCAACAAA
CCCTTTGTCTTCTTAATGATTGAACAAAATACCAAGTCTCCCCTCTTCATGGGAAAAGTGGTGAATCCCACCCAAAAATA
ACTGCCTCTCGCTCCTCAACCCCTCCCCTCCATCCCTGGCCCCCTCCCTGGATGACATTAAAGAAGGGTTGAGCTGGTCC
CTGCCTGCATGTGACTGTAAATCCCTCCCATGTTTTCTCTGAGTCTCCCTTTGCCTGCTGAGGCTGTATGTGGGCTCCAG
GTAACAGTGCTGTCTTCGGGCCCCCTGAACTGTGTTCATGGAGCATCTGGCTGGGTAGGCACATGCTGGGCTTGAATCCA
GGGGGGACTGAATCCTCAGCTTACGGACCTGGGCCCATCTGTTTCTGGAGGGCTCCAGTCTTCCTTGTCCTGTCTTGGAG
TCCCCAAGAAGGAATCACAGGGGAGGAACCAGATACCAGCCATGACCCCAGGCTCCACCAAGCATCTTCATGTCCCCCTG
CTCATCCCCCACTCCCCCCCACCCAGAGTTGCTCATCCTGCCAGGGCTGGCTGTGCCCACCCCAAGGCTGCCCTCCTGGG
GGCCCCAGAACTGCCTGATCGTGCCGTGGCCCAGTTTTGTGGCATCTGCAGCAACACAAGAGAGAGGACAATGTCCTCCT
CTTGACCCGCTGTCACCTAACCAGACTCGGGCCCTGCACCTCTCAGGCACTTCTGGAAAATGACTGAGGCAGATTCTTCC
TGAAGCCCATTCTCCATGGGGCAACAAGGACACCTATTCTGTCCTTGTCCTTCCATCGCTGCCCCAGAAAGCCTCACATA
TCTCCGTTTAGAATCAGGTCCCTTCTCCCCAGATGAAGAGGAGGGTCTCTGCTTTGTTTTCTCTATCTCCTCCTCAGACT
TGACCAGGCCCAGCAGGCCCCAGAAGACCATTACCCTATATCCCTTCTCCTCCCTAGTCACATGGCCATAGGCCTGCTGA
TGGCTCAGGAAGGCCATTGCAAGGACTCCTCAGCTATGGGAGAGGAAGCACATCACCCATTGACCCCCGCAACCCCTCCC
TTTCCTCCTCTGAGTCCCGACTGGGGCCACATGCAGCCTGACTTCTTTGTGCCTGTTGCTGTCCCTGCAGTCTTCAGAGG
GCCACCGCAGCTCCAGTGCCACGGCAGGAGGCTGTTCCTGAATAGCCCCTGTGGTAAGGGCCAGGAGAGTCCTTCCATCC
TCCAAGGCCCTGCTAAAGGACACAGCAGCCAGGAAGTCCCCTGGGCCCCTAGCTGAAGGACAGCCTGCTCCCTCCGTCTC
TACCAGGAATGGCCTTGTCCTATGGAAGGCACTGCCCCATCCCAAACTAATCTAGGAATCACTGTCTAACCACTCACTGT
CATGAATGTGTACTTAAAGGATGAGGTTGAGTCATACCAAATAGTGATTTCGATAGTTCAAAATGGTGAAATTAGCAATT
CTACATGATTCAGTCTAATCAATGGATACCGACTGTTTCCCACACAAGTCTCCTGTTCTCTTAAGCTTACTCACTGACAG
CCTTTCACTCTCCACAAATACATTAAAGATATGGCCATCACCAAGCCCCCTAGGATGACACCAGACCTGAGAGTCTGAAG
ACCTGGATCCAAGTTCTGACTTTTCCCCCTGACAGCTGTGTGACCTTCGTGAAGTCGCCAAACCTCTCTGAGCCCCAGTC
ATTGCTAGTAAGACCTGCCTTTGAGTTGGTATGATGTTCAAGTTAGATAACAAAATGTTTATACCCATTAGAACAGAGAA
TAAATAGAACTACATTTCTTGCA
|
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| |
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|
|
|
|
|
|
|
|
|
Primary source |
RefSeq : NM_001127707.1 (GI:189163541)
|
Name |
Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (SERPINA1), transcript variant 11
|
Type of transcript |
mRNA
|
Organism |
Homo sapiens
|
Length |
3300 nt
|
Map |
14q32.1
|
Location |
Chromosome 14 (NC_000014.8) strand : -
94843083...94844976 | 94845800...94845947 | 94847207...94847477 | 94848928...94849577 |
94854896...94854996 | 94856793...94857028 |
|
|
|
|
|
|
|
|
|
|
|
|
|
Exon(s) |
Start |
End |
Length |
is coding |
Exon 1a
|
1
|
236
|
236
|
1
|
Exon 2e
|
237
|
337
|
101
|
1
|
Exon 3
|
338
|
987
|
650
|
1
|
Exon 4
|
988
|
1258
|
271
|
1
|
Exon 5
|
1259
|
1406
|
148
|
1
|
Exon 6
|
1407
|
3300
|
1894
|
1
|
|
|
|
|
|
|
|
|
|
|
|
|
ID |
Class |
Location |
Mutation |
Length |
is synonymous |
Source |
|
|
|
|
|
|
|
|
|
|
|
|
Primary source |
NCBI : CCDS9925
|
Nucleotide |
SERPINA1, mRNA isoform 11[NM_001127707.1] : 342...1598
|
Length |
1257
|
Location |
Chromosome 14 (NC_000014.8) strand : -
94844785...94844976 | 94845800...94845947 | 94847207...94847477 | 94848928...94849573 |
|
Start codon |
1
|
Translation |
NP_001121179.1 |
|
|
|
|
|
|
|
|
|
|
|
|
1 |
TGGGCAGGAA |
CTGGGCACTG |
TGCCCAGGGC |
ATGCACTGCC |
TCCACGCAGC |
AACCCTCAGA |
GTCCTGAGCT |
GAACCAAGAA |
|
81 |
GGAGGAGGGG |
GTCGGGCCTC |
CGAGGAAGGC |
CTAGCCGCTG |
CTGCTGCCAG |
GAATTCCAGG |
TTGGAGGGGC |
GGCAACCTCC |
|
161 |
TGCCAGCCTT |
CAGGCCACTC |
TCCTGTGCCT |
GCCAGAAGAG |
ACAGAGCTTG |
AGGAGAGCTT |
GAGGAGAGCA |
GGAAAGCCTC |
|
241 |
CCCCGTTGCC |
CCTCTGGATC |
CACTGCTTAA |
ATACGGACGA |
GGACAGGGCC |
CTGTCTCCTC |
AGCTTCAGGC |
ACCACCACTG |
|
321 |
ACCTGGGACA |
GTGAATCGAC |
AATGCCGTCT |
TCTGTCTCGT |
GGGGCATCCT |
CCTGCTGGCA |
GGCCTGTGCT |
GCCTGGTCCC |
|
401 |
TGTCTCCCTG |
GCTGAGGATC |
CCCAGGGAGA |
TGCTGCCCAG |
AAGACAGATA |
CATCCCACCA |
TGATCAGGAT |
CACCCAACCT |
|
481 |
TCAACAAGAT |
CACCCCCAAC |
CTGGCTGAGT |
TCGCCTTCAG |
CCTATACCGC |
CAGCTGGCAC |
ACCAGTCCAA |
CAGCACCAAT |
|
561 |
ATCTTCTTCT |
CCCCAGTGAG |
CATCGCTACA |
GCCTTTGCAA |
TGCTCTCCCT |
GGGGACCAAG |
GCTGACACTC |
ACGATGAAAT |
|
641 |
CCTGGAGGGC |
CTGAATTTCA |
ACCTCACGGA |
GATTCCGGAG |
GCTCAGATCC |
ATGAAGGCTT |
CCAGGAACTC |
CTCCGTACCC |
|
721 |
TCAACCAGCC |
AGACAGCCAG |
CTCCAGCTGA |
CCACCGGCAA |
TGGCCTGTTC |
CTCAGCGAGG |
GCCTGAAGCT |
AGTGGATAAG |
|
801 |
TTTTTGGAGG |
ATGTTAAAAA |
GTTGTACCAC |
TCAGAAGCCT |
TCACTGTCAA |
CTTCGGGGAC |
ACCGAAGAGG |
CCAAGAAACA |
|
881 |
GATCAACGAT |
TACGTGGAGA |
AGGGTACTCA |
AGGGAAAATT |
GTGGATTTGG |
TCAAGGAGCT |
TGACAGAGAC |
ACAGTTTTTG |
|
961 |
CTCTGGTGAA |
TTACATCTTC |
TTTAAAGGCA |
AATGGGAGAG |
ACCCTTTGAA |
GTCAAGGACA |
CCGAGGAAGA |
GGACTTCCAC |
|
1041 |
GTGGACCAGG |
TGACCACCGT |
GAAGGTGCCT |
ATGATGAAGC |
GTTTAGGCAT |
GTTTAACATC |
CAGCACTGTA |
AGAAGCTGTC |
|
1121 |
CAGCTGGGTG |
CTGCTGATGA |
AATACCTGGG |
CAATGCCACC |
GCCATCTTCT |
TCCTGCCTGA |
TGAGGGGAAA |
CTACAGCACC |
|
1201 |
TGGAAAATGA |
ACTCACCCAC |
GATATCATCA |
CCAAGTTCCT |
GGAAAATGAA |
GACAGAAGGT |
CTGCCAGCTT |
ACATTTACCC |
|
1281 |
AAACTGTCCA |
TTACTGGAAC |
CTATGATCTG |
AAGAGCGTCC |
TGGGTCAACT |
GGGCATCACT |
AAGGTCTTCA |
GCAATGGGGC |
|
1361 |
TGACCTCTCC |
GGGGTCACAG |
AGGAGGCACC |
CCTGAAGCTC |
TCCAAGGCCG |
TGCATAAGGC |
TGTGCTGACC |
ATCGACGAGA |
|
1441 |
AAGGGACTGA |
AGCTGCTGGG |
GCCATGTTTT |
TAGAGGCCAT |
ACCCATGTCT |
ATCCCCCCCG |
AGGTCAAGTT |
CAACAAACCC |
|
1521 |
TTTGTCTTCT |
TAATGATTGA |
ACAAAATACC |
AAGTCTCCCC |
TCTTCATGGG |
AAAAGTGGTG |
AATCCCACCC |
AAAAATAACT |
|
1601 |
GCCTCTCGCT |
CCTCAACCCC |
TCCCCTCCAT |
CCCTGGCCCC |
CTCCCTGGAT |
GACATTAAAG |
AAGGGTTGAG |
CTGGTCCCTG |
|
1681 |
CCTGCATGTG |
ACTGTAAATC |
CCTCCCATGT |
TTTCTCTGAG |
TCTCCCTTTG |
CCTGCTGAGG |
CTGTATGTGG |
GCTCCAGGTA |
|
1761 |
ACAGTGCTGT |
CTTCGGGCCC |
CCTGAACTGT |
GTTCATGGAG |
CATCTGGCTG |
GGTAGGCACA |
TGCTGGGCTT |
GAATCCAGGG |
|
1841 |
GGGACTGAAT |
CCTCAGCTTA |
CGGACCTGGG |
CCCATCTGTT |
TCTGGAGGGC |
TCCAGTCTTC |
CTTGTCCTGT |
CTTGGAGTCC |
|
1921 |
CCAAGAAGGA |
ATCACAGGGG |
AGGAACCAGA |
TACCAGCCAT |
GACCCCAGGC |
TCCACCAAGC |
ATCTTCATGT |
CCCCCTGCTC |
|
2001 |
ATCCCCCACT |
CCCCCCCACC |
CAGAGTTGCT |
CATCCTGCCA |
GGGCTGGCTG |
TGCCCACCCC |
AAGGCTGCCC |
TCCTGGGGGC |
|
2081 |
CCCAGAACTG |
CCTGATCGTG |
CCGTGGCCCA |
GTTTTGTGGC |
ATCTGCAGCA |
ACACAAGAGA |
GAGGACAATG |
TCCTCCTCTT |
|
2161 |
GACCCGCTGT |
CACCTAACCA |
GACTCGGGCC |
CTGCACCTCT |
CAGGCACTTC |
TGGAAAATGA |
CTGAGGCAGA |
TTCTTCCTGA |
|
2241 |
AGCCCATTCT |
CCATGGGGCA |
ACAAGGACAC |
CTATTCTGTC |
CTTGTCCTTC |
CATCGCTGCC |
CCAGAAAGCC |
TCACATATCT |
|
2321 |
CCGTTTAGAA |
TCAGGTCCCT |
TCTCCCCAGA |
TGAAGAGGAG |
GGTCTCTGCT |
TTGTTTTCTC |
TATCTCCTCC |
TCAGACTTGA |
|
2401 |
CCAGGCCCAG |
CAGGCCCCAG |
AAGACCATTA |
CCCTATATCC |
CTTCTCCTCC |
CTAGTCACAT |
GGCCATAGGC |
CTGCTGATGG |
|
2481 |
CTCAGGAAGG |
CCATTGCAAG |
GACTCCTCAG |
CTATGGGAGA |
GGAAGCACAT |
CACCCATTGA |
CCCCCGCAAC |
CCCTCCCTTT |
|
2561 |
CCTCCTCTGA |
GTCCCGACTG |
GGGCCACATG |
CAGCCTGACT |
TCTTTGTGCC |
TGTTGCTGTC |
CCTGCAGTCT |
TCAGAGGGCC |
|
2641 |
ACCGCAGCTC |
CAGTGCCACG |
GCAGGAGGCT |
GTTCCTGAAT |
AGCCCCTGTG |
GTAAGGGCCA |
GGAGAGTCCT |
TCCATCCTCC |
|
2721 |
AAGGCCCTGC |
TAAAGGACAC |
AGCAGCCAGG |
AAGTCCCCTG |
GGCCCCTAGC |
TGAAGGACAG |
CCTGCTCCCT |
CCGTCTCTAC |
|
2801 |
CAGGAATGGC |
CTTGTCCTAT |
GGAAGGCACT |
GCCCCATCCC |
AAACTAATCT |
AGGAATCACT |
GTCTAACCAC |
TCACTGTCAT |
|
2881 |
GAATGTGTAC |
TTAAAGGATG |
AGGTTGAGTC |
ATACCAAATA |
GTGATTTCGA |
TAGTTCAAAA |
TGGTGAAATT |
AGCAATTCTA |
|
2961 |
CATGATTCAG |
TCTAATCAAT |
GGATACCGAC |
TGTTTCCCAC |
ACAAGTCTCC |
TGTTCTCTTA |
AGCTTACTCA |
CTGACAGCCT |
|
3041 |
TTCACTCTCC |
ACAAATACAT |
TAAAGATATG |
GCCATCACCA |
AGCCCCCTAG |
GATGACACCA |
GACCTGAGAG |
TCTGAAGACC |
|
3121 |
TGGATCCAAG |
TTCTGACTTT |
TCCCCCTGAC |
AGCTGTGTGA |
CCTTCGTGAA |
GTCGCCAAAC |
CTCTCTGAGC |
CCCAGTCATT |
|
3201 |
GCTAGTAAGA |
CCTGCCTTTG |
AGTTGGTATG |
ATGTTCAAGT |
TAGATAACAA |
AATGTTTATA |
CCCATTAGAA |
CAGAGAATAA |
|
3281 |
ATAGAACTAC |
ATTTCTTGCA |
|
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|
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>gi|189163541|ref|NM_001127707.1|Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (SERPINA1), transcript variant 11
TGGGCAGGAACTGGGCACTGTGCCCAGGGCATGCACTGCCTCCACGCAGCAACCCTCAGAGTCCTGAGCTGAACCAAGAA
GGAGGAGGGGGTCGGGCCTCCGAGGAAGGCCTAGCCGCTGCTGCTGCCAGGAATTCCAGGTTGGAGGGGCGGCAACCTCC
TGCCAGCCTTCAGGCCACTCTCCTGTGCCTGCCAGAAGAGACAGAGCTTGAGGAGAGCTTGAGGAGAGCAGGAAAGCCTC
CCCCGTTGCCCCTCTGGATCCACTGCTTAAATACGGACGAGGACAGGGCCCTGTCTCCTCAGCTTCAGGCACCACCACTG
ACCTGGGACAGTGAATCGACAATGCCGTCTTCTGTCTCGTGGGGCATCCTCCTGCTGGCAGGCCTGTGCTGCCTGGTCCC
TGTCTCCCTGGCTGAGGATCCCCAGGGAGATGCTGCCCAGAAGACAGATACATCCCACCATGATCAGGATCACCCAACCT
TCAACAAGATCACCCCCAACCTGGCTGAGTTCGCCTTCAGCCTATACCGCCAGCTGGCACACCAGTCCAACAGCACCAAT
ATCTTCTTCTCCCCAGTGAGCATCGCTACAGCCTTTGCAATGCTCTCCCTGGGGACCAAGGCTGACACTCACGATGAAAT
CCTGGAGGGCCTGAATTTCAACCTCACGGAGATTCCGGAGGCTCAGATCCATGAAGGCTTCCAGGAACTCCTCCGTACCC
TCAACCAGCCAGACAGCCAGCTCCAGCTGACCACCGGCAATGGCCTGTTCCTCAGCGAGGGCCTGAAGCTAGTGGATAAG
TTTTTGGAGGATGTTAAAAAGTTGTACCACTCAGAAGCCTTCACTGTCAACTTCGGGGACACCGAAGAGGCCAAGAAACA
GATCAACGATTACGTGGAGAAGGGTACTCAAGGGAAAATTGTGGATTTGGTCAAGGAGCTTGACAGAGACACAGTTTTTG
CTCTGGTGAATTACATCTTCTTTAAAGGCAAATGGGAGAGACCCTTTGAAGTCAAGGACACCGAGGAAGAGGACTTCCAC
GTGGACCAGGTGACCACCGTGAAGGTGCCTATGATGAAGCGTTTAGGCATGTTTAACATCCAGCACTGTAAGAAGCTGTC
CAGCTGGGTGCTGCTGATGAAATACCTGGGCAATGCCACCGCCATCTTCTTCCTGCCTGATGAGGGGAAACTACAGCACC
TGGAAAATGAACTCACCCACGATATCATCACCAAGTTCCTGGAAAATGAAGACAGAAGGTCTGCCAGCTTACATTTACCC
AAACTGTCCATTACTGGAACCTATGATCTGAAGAGCGTCCTGGGTCAACTGGGCATCACTAAGGTCTTCAGCAATGGGGC
TGACCTCTCCGGGGTCACAGAGGAGGCACCCCTGAAGCTCTCCAAGGCCGTGCATAAGGCTGTGCTGACCATCGACGAGA
AAGGGACTGAAGCTGCTGGGGCCATGTTTTTAGAGGCCATACCCATGTCTATCCCCCCCGAGGTCAAGTTCAACAAACCC
TTTGTCTTCTTAATGATTGAACAAAATACCAAGTCTCCCCTCTTCATGGGAAAAGTGGTGAATCCCACCCAAAAATAACT
GCCTCTCGCTCCTCAACCCCTCCCCTCCATCCCTGGCCCCCTCCCTGGATGACATTAAAGAAGGGTTGAGCTGGTCCCTG
CCTGCATGTGACTGTAAATCCCTCCCATGTTTTCTCTGAGTCTCCCTTTGCCTGCTGAGGCTGTATGTGGGCTCCAGGTA
ACAGTGCTGTCTTCGGGCCCCCTGAACTGTGTTCATGGAGCATCTGGCTGGGTAGGCACATGCTGGGCTTGAATCCAGGG
GGGACTGAATCCTCAGCTTACGGACCTGGGCCCATCTGTTTCTGGAGGGCTCCAGTCTTCCTTGTCCTGTCTTGGAGTCC
CCAAGAAGGAATCACAGGGGAGGAACCAGATACCAGCCATGACCCCAGGCTCCACCAAGCATCTTCATGTCCCCCTGCTC
ATCCCCCACTCCCCCCCACCCAGAGTTGCTCATCCTGCCAGGGCTGGCTGTGCCCACCCCAAGGCTGCCCTCCTGGGGGC
CCCAGAACTGCCTGATCGTGCCGTGGCCCAGTTTTGTGGCATCTGCAGCAACACAAGAGAGAGGACAATGTCCTCCTCTT
GACCCGCTGTCACCTAACCAGACTCGGGCCCTGCACCTCTCAGGCACTTCTGGAAAATGACTGAGGCAGATTCTTCCTGA
AGCCCATTCTCCATGGGGCAACAAGGACACCTATTCTGTCCTTGTCCTTCCATCGCTGCCCCAGAAAGCCTCACATATCT
CCGTTTAGAATCAGGTCCCTTCTCCCCAGATGAAGAGGAGGGTCTCTGCTTTGTTTTCTCTATCTCCTCCTCAGACTTGA
CCAGGCCCAGCAGGCCCCAGAAGACCATTACCCTATATCCCTTCTCCTCCCTAGTCACATGGCCATAGGCCTGCTGATGG
CTCAGGAAGGCCATTGCAAGGACTCCTCAGCTATGGGAGAGGAAGCACATCACCCATTGACCCCCGCAACCCCTCCCTTT
CCTCCTCTGAGTCCCGACTGGGGCCACATGCAGCCTGACTTCTTTGTGCCTGTTGCTGTCCCTGCAGTCTTCAGAGGGCC
ACCGCAGCTCCAGTGCCACGGCAGGAGGCTGTTCCTGAATAGCCCCTGTGGTAAGGGCCAGGAGAGTCCTTCCATCCTCC
AAGGCCCTGCTAAAGGACACAGCAGCCAGGAAGTCCCCTGGGCCCCTAGCTGAAGGACAGCCTGCTCCCTCCGTCTCTAC
CAGGAATGGCCTTGTCCTATGGAAGGCACTGCCCCATCCCAAACTAATCTAGGAATCACTGTCTAACCACTCACTGTCAT
GAATGTGTACTTAAAGGATGAGGTTGAGTCATACCAAATAGTGATTTCGATAGTTCAAAATGGTGAAATTAGCAATTCTA
CATGATTCAGTCTAATCAATGGATACCGACTGTTTCCCACACAAGTCTCCTGTTCTCTTAAGCTTACTCACTGACAGCCT
TTCACTCTCCACAAATACATTAAAGATATGGCCATCACCAAGCCCCCTAGGATGACACCAGACCTGAGAGTCTGAAGACC
TGGATCCAAGTTCTGACTTTTCCCCCTGACAGCTGTGTGACCTTCGTGAAGTCGCCAAACCTCTCTGAGCCCCAGTCATT
GCTAGTAAGACCTGCCTTTGAGTTGGTATGATGTTCAAGTTAGATAACAAAATGTTTATACCCATTAGAACAGAGAATAA
ATAGAACTACATTTCTTGCA
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Primary source |
RefSeq : NM_001002236.2 (GI:189163526)
|
Name |
Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (SERPINA1), transcript variant 2
|
Type of transcript |
mRNA
|
Organism |
Homo sapiens
|
Length |
3513 nt
|
Map |
14q32.1
|
Location |
Chromosome 14 (NC_000014.8) strand : -
94843083...94844976 | 94845800...94845947 | 94847207...94847477 | 94848928...94849577 |
94854896...94854999 | 94855137...94855346 | 94856793...94857028 |
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|
Exon(s) |
Start |
End |
Length |
is coding |
Exon 1a
|
1
|
236
|
236
|
1
|
Exon 2b
|
237
|
446
|
210
|
1
|
Exon 2d
|
447
|
550
|
104
|
1
|
Exon 3
|
551
|
1200
|
650
|
1
|
Exon 4
|
1201
|
1471
|
271
|
1
|
Exon 5
|
1472
|
1619
|
148
|
1
|
Exon 6
|
1620
|
3513
|
1894
|
1
|
|
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ID |
Class |
Location |
Mutation |
Length |
is synonymous |
Source |
|
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|
Primary source |
NCBI : CCDS9925
|
Nucleotide |
SERPINA1, mRNA isoform 2[NM_001002236.2] : 555...1811
|
Length |
1257
|
Location |
Chromosome 14 (NC_000014.8) strand : -
94844785...94844976 | 94845800...94845947 | 94847207...94847477 | 94848928...94849573 |
|
Start codon |
1
|
Translation |
NP_001002236.1 |
|
|
|
|
|
|
|
|
|
|
|
|
1 |
TGGGCAGGAA |
CTGGGCACTG |
TGCCCAGGGC |
ATGCACTGCC |
TCCACGCAGC |
AACCCTCAGA |
GTCCTGAGCT |
GAACCAAGAA |
|
81 |
GGAGGAGGGG |
GTCGGGCCTC |
CGAGGAAGGC |
CTAGCCGCTG |
CTGCTGCCAG |
GAATTCCAGG |
TTGGAGGGGC |
GGCAACCTCC |
|
161 |
TGCCAGCCTT |
CAGGCCACTC |
TCCTGTGCCT |
GCCAGAAGAG |
ACAGAGCTTG |
AGGAGAGCTT |
GAGGAGAGCA |
GGAAAGGGCG |
|
241 |
GCAGTAAGTC |
TTCAGCATCA |
GGCATTTTGG |
GGTGACTCAG |
TAAATGGTAG |
ATCTTGCTAC |
CAGTGGAACA |
GCCACTAAGG |
|
321 |
ATTCTGCAGT |
GAGAGCAGAG |
GGCCAGCTAA |
GTGGTACTCT |
CCCAGAGACT |
GTCTGACTCA |
CGCCACCCCC |
TCCACCTTGG |
|
401 |
ACACAGGACG |
CTGTGGTTTC |
TGAGCCAGGT |
ACAATGACTC |
CTTTCGCAGC |
CTCCCCCGTT |
GCCCCTCTGG |
ATCCACTGCT |
|
481 |
TAAATACGGA |
CGAGGACAGG |
GCCCTGTCTC |
CTCAGCTTCA |
GGCACCACCA |
CTGACCTGGG |
ACAGTGAATC |
GACAATGCCG |
|
561 |
TCTTCTGTCT |
CGTGGGGCAT |
CCTCCTGCTG |
GCAGGCCTGT |
GCTGCCTGGT |
CCCTGTCTCC |
CTGGCTGAGG |
ATCCCCAGGG |
|
641 |
AGATGCTGCC |
CAGAAGACAG |
ATACATCCCA |
CCATGATCAG |
GATCACCCAA |
CCTTCAACAA |
GATCACCCCC |
AACCTGGCTG |
|
721 |
AGTTCGCCTT |
CAGCCTATAC |
CGCCAGCTGG |
CACACCAGTC |
CAACAGCACC |
AATATCTTCT |
TCTCCCCAGT |
GAGCATCGCT |
|
801 |
ACAGCCTTTG |
CAATGCTCTC |
CCTGGGGACC |
AAGGCTGACA |
CTCACGATGA |
AATCCTGGAG |
GGCCTGAATT |
TCAACCTCAC |
|
881 |
GGAGATTCCG |
GAGGCTCAGA |
TCCATGAAGG |
CTTCCAGGAA |
CTCCTCCGTA |
CCCTCAACCA |
GCCAGACAGC |
CAGCTCCAGC |
|
961 |
TGACCACCGG |
CAATGGCCTG |
TTCCTCAGCG |
AGGGCCTGAA |
GCTAGTGGAT |
AAGTTTTTGG |
AGGATGTTAA |
AAAGTTGTAC |
|
1041 |
CACTCAGAAG |
CCTTCACTGT |
CAACTTCGGG |
GACACCGAAG |
AGGCCAAGAA |
ACAGATCAAC |
GATTACGTGG |
AGAAGGGTAC |
|
1121 |
TCAAGGGAAA |
ATTGTGGATT |
TGGTCAAGGA |
GCTTGACAGA |
GACACAGTTT |
TTGCTCTGGT |
GAATTACATC |
TTCTTTAAAG |
|
1201 |
GCAAATGGGA |
GAGACCCTTT |
GAAGTCAAGG |
ACACCGAGGA |
AGAGGACTTC |
CACGTGGACC |
AGGTGACCAC |
CGTGAAGGTG |
|
1281 |
CCTATGATGA |
AGCGTTTAGG |
CATGTTTAAC |
ATCCAGCACT |
GTAAGAAGCT |
GTCCAGCTGG |
GTGCTGCTGA |
TGAAATACCT |
|
1361 |
GGGCAATGCC |
ACCGCCATCT |
TCTTCCTGCC |
TGATGAGGGG |
AAACTACAGC |
ACCTGGAAAA |
TGAACTCACC |
CACGATATCA |
|
1441 |
TCACCAAGTT |
CCTGGAAAAT |
GAAGACAGAA |
GGTCTGCCAG |
CTTACATTTA |
CCCAAACTGT |
CCATTACTGG |
AACCTATGAT |
|
1521 |
CTGAAGAGCG |
TCCTGGGTCA |
ACTGGGCATC |
ACTAAGGTCT |
TCAGCAATGG |
GGCTGACCTC |
TCCGGGGTCA |
CAGAGGAGGC |
|
1601 |
ACCCCTGAAG |
CTCTCCAAGG |
CCGTGCATAA |
GGCTGTGCTG |
ACCATCGACG |
AGAAAGGGAC |
TGAAGCTGCT |
GGGGCCATGT |
|
1681 |
TTTTAGAGGC |
CATACCCATG |
TCTATCCCCC |
CCGAGGTCAA |
GTTCAACAAA |
CCCTTTGTCT |
TCTTAATGAT |
TGAACAAAAT |
|
1761 |
ACCAAGTCTC |
CCCTCTTCAT |
GGGAAAAGTG |
GTGAATCCCA |
CCCAAAAATA |
ACTGCCTCTC |
GCTCCTCAAC |
CCCTCCCCTC |
|
1841 |
CATCCCTGGC |
CCCCTCCCTG |
GATGACATTA |
AAGAAGGGTT |
GAGCTGGTCC |
CTGCCTGCAT |
GTGACTGTAA |
ATCCCTCCCA |
|
1921 |
TGTTTTCTCT |
GAGTCTCCCT |
TTGCCTGCTG |
AGGCTGTATG |
TGGGCTCCAG |
GTAACAGTGC |
TGTCTTCGGG |
CCCCCTGAAC |
|
2001 |
TGTGTTCATG |
GAGCATCTGG |
CTGGGTAGGC |
ACATGCTGGG |
CTTGAATCCA |
GGGGGGACTG |
AATCCTCAGC |
TTACGGACCT |
|
2081 |
GGGCCCATCT |
GTTTCTGGAG |
GGCTCCAGTC |
TTCCTTGTCC |
TGTCTTGGAG |
TCCCCAAGAA |
GGAATCACAG |
GGGAGGAACC |
|
2161 |
AGATACCAGC |
CATGACCCCA |
GGCTCCACCA |
AGCATCTTCA |
TGTCCCCCTG |
CTCATCCCCC |
ACTCCCCCCC |
ACCCAGAGTT |
|
2241 |
GCTCATCCTG |
CCAGGGCTGG |
CTGTGCCCAC |
CCCAAGGCTG |
CCCTCCTGGG |
GGCCCCAGAA |
CTGCCTGATC |
GTGCCGTGGC |
|
2321 |
CCAGTTTTGT |
GGCATCTGCA |
GCAACACAAG |
AGAGAGGACA |
ATGTCCTCCT |
CTTGACCCGC |
TGTCACCTAA |
CCAGACTCGG |
|
2401 |
GCCCTGCACC |
TCTCAGGCAC |
TTCTGGAAAA |
TGACTGAGGC |
AGATTCTTCC |
TGAAGCCCAT |
TCTCCATGGG |
GCAACAAGGA |
|
2481 |
CACCTATTCT |
GTCCTTGTCC |
TTCCATCGCT |
GCCCCAGAAA |
GCCTCACATA |
TCTCCGTTTA |
GAATCAGGTC |
CCTTCTCCCC |
|
2561 |
AGATGAAGAG |
GAGGGTCTCT |
GCTTTGTTTT |
CTCTATCTCC |
TCCTCAGACT |
TGACCAGGCC |
CAGCAGGCCC |
CAGAAGACCA |
|
2641 |
TTACCCTATA |
TCCCTTCTCC |
TCCCTAGTCA |
CATGGCCATA |
GGCCTGCTGA |
TGGCTCAGGA |
AGGCCATTGC |
AAGGACTCCT |
|
2721 |
CAGCTATGGG |
AGAGGAAGCA |
CATCACCCAT |
TGACCCCCGC |
AACCCCTCCC |
TTTCCTCCTC |
TGAGTCCCGA |
CTGGGGCCAC |
|
2801 |
ATGCAGCCTG |
ACTTCTTTGT |
GCCTGTTGCT |
GTCCCTGCAG |
TCTTCAGAGG |
GCCACCGCAG |
CTCCAGTGCC |
ACGGCAGGAG |
|
2881 |
GCTGTTCCTG |
AATAGCCCCT |
GTGGTAAGGG |
CCAGGAGAGT |
CCTTCCATCC |
TCCAAGGCCC |
TGCTAAAGGA |
CACAGCAGCC |
|
2961 |
AGGAAGTCCC |
CTGGGCCCCT |
AGCTGAAGGA |
CAGCCTGCTC |
CCTCCGTCTC |
TACCAGGAAT |
GGCCTTGTCC |
TATGGAAGGC |
|
3041 |
ACTGCCCCAT |
CCCAAACTAA |
TCTAGGAATC |
ACTGTCTAAC |
CACTCACTGT |
CATGAATGTG |
TACTTAAAGG |
ATGAGGTTGA |
|
3121 |
GTCATACCAA |
ATAGTGATTT |
CGATAGTTCA |
AAATGGTGAA |
ATTAGCAATT |
CTACATGATT |
CAGTCTAATC |
AATGGATACC |
|
3201 |
GACTGTTTCC |
CACACAAGTC |
TCCTGTTCTC |
TTAAGCTTAC |
TCACTGACAG |
CCTTTCACTC |
TCCACAAATA |
CATTAAAGAT |
|
3281 |
ATGGCCATCA |
CCAAGCCCCC |
TAGGATGACA |
CCAGACCTGA |
GAGTCTGAAG |
ACCTGGATCC |
AAGTTCTGAC |
TTTTCCCCCT |
|
3361 |
GACAGCTGTG |
TGACCTTCGT |
GAAGTCGCCA |
AACCTCTCTG |
AGCCCCAGTC |
ATTGCTAGTA |
AGACCTGCCT |
TTGAGTTGGT |
|
3441 |
ATGATGTTCA |
AGTTAGATAA |
CAAAATGTTT |
ATACCCATTA |
GAACAGAGAA |
TAAATAGAAC |
TACATTTCTT |
GCA |
|
|
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|
>gi|189163526|ref|NM_001002236.2|Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (SERPINA1), transcript variant 2
TGGGCAGGAACTGGGCACTGTGCCCAGGGCATGCACTGCCTCCACGCAGCAACCCTCAGAGTCCTGAGCTGAACCAAGAA
GGAGGAGGGGGTCGGGCCTCCGAGGAAGGCCTAGCCGCTGCTGCTGCCAGGAATTCCAGGTTGGAGGGGCGGCAACCTCC
TGCCAGCCTTCAGGCCACTCTCCTGTGCCTGCCAGAAGAGACAGAGCTTGAGGAGAGCTTGAGGAGAGCAGGAAAGGGCG
GCAGTAAGTCTTCAGCATCAGGCATTTTGGGGTGACTCAGTAAATGGTAGATCTTGCTACCAGTGGAACAGCCACTAAGG
ATTCTGCAGTGAGAGCAGAGGGCCAGCTAAGTGGTACTCTCCCAGAGACTGTCTGACTCACGCCACCCCCTCCACCTTGG
ACACAGGACGCTGTGGTTTCTGAGCCAGGTACAATGACTCCTTTCGCAGCCTCCCCCGTTGCCCCTCTGGATCCACTGCT
TAAATACGGACGAGGACAGGGCCCTGTCTCCTCAGCTTCAGGCACCACCACTGACCTGGGACAGTGAATCGACAATGCCG
TCTTCTGTCTCGTGGGGCATCCTCCTGCTGGCAGGCCTGTGCTGCCTGGTCCCTGTCTCCCTGGCTGAGGATCCCCAGGG
AGATGCTGCCCAGAAGACAGATACATCCCACCATGATCAGGATCACCCAACCTTCAACAAGATCACCCCCAACCTGGCTG
AGTTCGCCTTCAGCCTATACCGCCAGCTGGCACACCAGTCCAACAGCACCAATATCTTCTTCTCCCCAGTGAGCATCGCT
ACAGCCTTTGCAATGCTCTCCCTGGGGACCAAGGCTGACACTCACGATGAAATCCTGGAGGGCCTGAATTTCAACCTCAC
GGAGATTCCGGAGGCTCAGATCCATGAAGGCTTCCAGGAACTCCTCCGTACCCTCAACCAGCCAGACAGCCAGCTCCAGC
TGACCACCGGCAATGGCCTGTTCCTCAGCGAGGGCCTGAAGCTAGTGGATAAGTTTTTGGAGGATGTTAAAAAGTTGTAC
CACTCAGAAGCCTTCACTGTCAACTTCGGGGACACCGAAGAGGCCAAGAAACAGATCAACGATTACGTGGAGAAGGGTAC
TCAAGGGAAAATTGTGGATTTGGTCAAGGAGCTTGACAGAGACACAGTTTTTGCTCTGGTGAATTACATCTTCTTTAAAG
GCAAATGGGAGAGACCCTTTGAAGTCAAGGACACCGAGGAAGAGGACTTCCACGTGGACCAGGTGACCACCGTGAAGGTG
CCTATGATGAAGCGTTTAGGCATGTTTAACATCCAGCACTGTAAGAAGCTGTCCAGCTGGGTGCTGCTGATGAAATACCT
GGGCAATGCCACCGCCATCTTCTTCCTGCCTGATGAGGGGAAACTACAGCACCTGGAAAATGAACTCACCCACGATATCA
TCACCAAGTTCCTGGAAAATGAAGACAGAAGGTCTGCCAGCTTACATTTACCCAAACTGTCCATTACTGGAACCTATGAT
CTGAAGAGCGTCCTGGGTCAACTGGGCATCACTAAGGTCTTCAGCAATGGGGCTGACCTCTCCGGGGTCACAGAGGAGGC
ACCCCTGAAGCTCTCCAAGGCCGTGCATAAGGCTGTGCTGACCATCGACGAGAAAGGGACTGAAGCTGCTGGGGCCATGT
TTTTAGAGGCCATACCCATGTCTATCCCCCCCGAGGTCAAGTTCAACAAACCCTTTGTCTTCTTAATGATTGAACAAAAT
ACCAAGTCTCCCCTCTTCATGGGAAAAGTGGTGAATCCCACCCAAAAATAACTGCCTCTCGCTCCTCAACCCCTCCCCTC
CATCCCTGGCCCCCTCCCTGGATGACATTAAAGAAGGGTTGAGCTGGTCCCTGCCTGCATGTGACTGTAAATCCCTCCCA
TGTTTTCTCTGAGTCTCCCTTTGCCTGCTGAGGCTGTATGTGGGCTCCAGGTAACAGTGCTGTCTTCGGGCCCCCTGAAC
TGTGTTCATGGAGCATCTGGCTGGGTAGGCACATGCTGGGCTTGAATCCAGGGGGGACTGAATCCTCAGCTTACGGACCT
GGGCCCATCTGTTTCTGGAGGGCTCCAGTCTTCCTTGTCCTGTCTTGGAGTCCCCAAGAAGGAATCACAGGGGAGGAACC
AGATACCAGCCATGACCCCAGGCTCCACCAAGCATCTTCATGTCCCCCTGCTCATCCCCCACTCCCCCCCACCCAGAGTT
GCTCATCCTGCCAGGGCTGGCTGTGCCCACCCCAAGGCTGCCCTCCTGGGGGCCCCAGAACTGCCTGATCGTGCCGTGGC
CCAGTTTTGTGGCATCTGCAGCAACACAAGAGAGAGGACAATGTCCTCCTCTTGACCCGCTGTCACCTAACCAGACTCGG
GCCCTGCACCTCTCAGGCACTTCTGGAAAATGACTGAGGCAGATTCTTCCTGAAGCCCATTCTCCATGGGGCAACAAGGA
CACCTATTCTGTCCTTGTCCTTCCATCGCTGCCCCAGAAAGCCTCACATATCTCCGTTTAGAATCAGGTCCCTTCTCCCC
AGATGAAGAGGAGGGTCTCTGCTTTGTTTTCTCTATCTCCTCCTCAGACTTGACCAGGCCCAGCAGGCCCCAGAAGACCA
TTACCCTATATCCCTTCTCCTCCCTAGTCACATGGCCATAGGCCTGCTGATGGCTCAGGAAGGCCATTGCAAGGACTCCT
CAGCTATGGGAGAGGAAGCACATCACCCATTGACCCCCGCAACCCCTCCCTTTCCTCCTCTGAGTCCCGACTGGGGCCAC
ATGCAGCCTGACTTCTTTGTGCCTGTTGCTGTCCCTGCAGTCTTCAGAGGGCCACCGCAGCTCCAGTGCCACGGCAGGAG
GCTGTTCCTGAATAGCCCCTGTGGTAAGGGCCAGGAGAGTCCTTCCATCCTCCAAGGCCCTGCTAAAGGACACAGCAGCC
AGGAAGTCCCCTGGGCCCCTAGCTGAAGGACAGCCTGCTCCCTCCGTCTCTACCAGGAATGGCCTTGTCCTATGGAAGGC
ACTGCCCCATCCCAAACTAATCTAGGAATCACTGTCTAACCACTCACTGTCATGAATGTGTACTTAAAGGATGAGGTTGA
GTCATACCAAATAGTGATTTCGATAGTTCAAAATGGTGAAATTAGCAATTCTACATGATTCAGTCTAATCAATGGATACC
GACTGTTTCCCACACAAGTCTCCTGTTCTCTTAAGCTTACTCACTGACAGCCTTTCACTCTCCACAAATACATTAAAGAT
ATGGCCATCACCAAGCCCCCTAGGATGACACCAGACCTGAGAGTCTGAAGACCTGGATCCAAGTTCTGACTTTTCCCCCT
GACAGCTGTGTGACCTTCGTGAAGTCGCCAAACCTCTCTGAGCCCCAGTCATTGCTAGTAAGACCTGCCTTTGAGTTGGT
ATGATGTTCAAGTTAGATAACAAAATGTTTATACCCATTAGAACAGAGAATAAATAGAACTACATTTCTTGCA
|
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| |
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|
Primary source |
RefSeq : NM_001002235.2 (GI:189163525)
|
Name |
Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (SERPINA1), transcript variant 3
|
Type of transcript |
mRNA
|
Organism |
Homo sapiens
|
Length |
3199 nt
|
Map |
14q32.1
|
Location |
Chromosome 14 (NC_000014.8) strand : -
94843083...94844976 | 94845800...94845947 | 94847207...94847477 | 94848928...94849577 |
94856793...94857028 |
|
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|
|
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|
|
|
|
|
|
|
|
Exon(s) |
Start |
End |
Length |
is coding |
Exon 1a
|
1
|
236
|
236
|
1
|
Exon 3
|
237
|
886
|
650
|
1
|
Exon 4
|
887
|
1157
|
271
|
1
|
Exon 5
|
1158
|
1305
|
148
|
1
|
Exon 6
|
1306
|
3199
|
1894
|
1
|
|
|
|
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|
|
|
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|
|
|
|
ID |
Class |
Location |
Mutation |
Length |
is synonymous |
Source |
|
|
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|
|
|
|
|
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|
|
|
Primary source |
NCBI : CCDS9925
|
Nucleotide |
SERPINA1, mRNA isoform 3[NM_001002235.2] : 241...1497
|
Length |
1257
|
Location |
Chromosome 14 (NC_000014.8) strand : -
94844785...94844976 | 94845800...94845947 | 94847207...94847477 | 94848928...94849573 |
|
Start codon |
1
|
Translation |
NP_001002235.1 |
|
|
|
|
|
|
|
|
|
|
|
|
1 |
TGGGCAGGAA |
CTGGGCACTG |
TGCCCAGGGC |
ATGCACTGCC |
TCCACGCAGC |
AACCCTCAGA |
GTCCTGAGCT |
GAACCAAGAA |
|
81 |
GGAGGAGGGG |
GTCGGGCCTC |
CGAGGAAGGC |
CTAGCCGCTG |
CTGCTGCCAG |
GAATTCCAGG |
TTGGAGGGGC |
GGCAACCTCC |
|
161 |
TGCCAGCCTT |
CAGGCCACTC |
TCCTGTGCCT |
GCCAGAAGAG |
ACAGAGCTTG |
AGGAGAGCTT |
GAGGAGAGCA |
GGAAAGGACA |
|
241 |
ATGCCGTCTT |
CTGTCTCGTG |
GGGCATCCTC |
CTGCTGGCAG |
GCCTGTGCTG |
CCTGGTCCCT |
GTCTCCCTGG |
CTGAGGATCC |
|
321 |
CCAGGGAGAT |
GCTGCCCAGA |
AGACAGATAC |
ATCCCACCAT |
GATCAGGATC |
ACCCAACCTT |
CAACAAGATC |
ACCCCCAACC |
|
401 |
TGGCTGAGTT |
CGCCTTCAGC |
CTATACCGCC |
AGCTGGCACA |
CCAGTCCAAC |
AGCACCAATA |
TCTTCTTCTC |
CCCAGTGAGC |
|
481 |
ATCGCTACAG |
CCTTTGCAAT |
GCTCTCCCTG |
GGGACCAAGG |
CTGACACTCA |
CGATGAAATC |
CTGGAGGGCC |
TGAATTTCAA |
|
561 |
CCTCACGGAG |
ATTCCGGAGG |
CTCAGATCCA |
TGAAGGCTTC |
CAGGAACTCC |
TCCGTACCCT |
CAACCAGCCA |
GACAGCCAGC |
|
641 |
TCCAGCTGAC |
CACCGGCAAT |
GGCCTGTTCC |
TCAGCGAGGG |
CCTGAAGCTA |
GTGGATAAGT |
TTTTGGAGGA |
TGTTAAAAAG |
|
721 |
TTGTACCACT |
CAGAAGCCTT |
CACTGTCAAC |
TTCGGGGACA |
CCGAAGAGGC |
CAAGAAACAG |
ATCAACGATT |
ACGTGGAGAA |
|
801 |
GGGTACTCAA |
GGGAAAATTG |
TGGATTTGGT |
CAAGGAGCTT |
GACAGAGACA |
CAGTTTTTGC |
TCTGGTGAAT |
TACATCTTCT |
|
881 |
TTAAAGGCAA |
ATGGGAGAGA |
CCCTTTGAAG |
TCAAGGACAC |
CGAGGAAGAG |
GACTTCCACG |
TGGACCAGGT |
GACCACCGTG |
|
961 |
AAGGTGCCTA |
TGATGAAGCG |
TTTAGGCATG |
TTTAACATCC |
AGCACTGTAA |
GAAGCTGTCC |
AGCTGGGTGC |
TGCTGATGAA |
|
1041 |
ATACCTGGGC |
AATGCCACCG |
CCATCTTCTT |
CCTGCCTGAT |
GAGGGGAAAC |
TACAGCACCT |
GGAAAATGAA |
CTCACCCACG |
|
1121 |
ATATCATCAC |
CAAGTTCCTG |
GAAAATGAAG |
ACAGAAGGTC |
TGCCAGCTTA |
CATTTACCCA |
AACTGTCCAT |
TACTGGAACC |
|
1201 |
TATGATCTGA |
AGAGCGTCCT |
GGGTCAACTG |
GGCATCACTA |
AGGTCTTCAG |
CAATGGGGCT |
GACCTCTCCG |
GGGTCACAGA |
|
1281 |
GGAGGCACCC |
CTGAAGCTCT |
CCAAGGCCGT |
GCATAAGGCT |
GTGCTGACCA |
TCGACGAGAA |
AGGGACTGAA |
GCTGCTGGGG |
|
1361 |
CCATGTTTTT |
AGAGGCCATA |
CCCATGTCTA |
TCCCCCCCGA |
GGTCAAGTTC |
AACAAACCCT |
TTGTCTTCTT |
AATGATTGAA |
|
1441 |
CAAAATACCA |
AGTCTCCCCT |
CTTCATGGGA |
AAAGTGGTGA |
ATCCCACCCA |
AAAATAACTG |
CCTCTCGCTC |
CTCAACCCCT |
|
1521 |
CCCCTCCATC |
CCTGGCCCCC |
TCCCTGGATG |
ACATTAAAGA |
AGGGTTGAGC |
TGGTCCCTGC |
CTGCATGTGA |
CTGTAAATCC |
|
1601 |
CTCCCATGTT |
TTCTCTGAGT |
CTCCCTTTGC |
CTGCTGAGGC |
TGTATGTGGG |
CTCCAGGTAA |
CAGTGCTGTC |
TTCGGGCCCC |
|
1681 |
CTGAACTGTG |
TTCATGGAGC |
ATCTGGCTGG |
GTAGGCACAT |
GCTGGGCTTG |
AATCCAGGGG |
GGACTGAATC |
CTCAGCTTAC |
|
1761 |
GGACCTGGGC |
CCATCTGTTT |
CTGGAGGGCT |
CCAGTCTTCC |
TTGTCCTGTC |
TTGGAGTCCC |
CAAGAAGGAA |
TCACAGGGGA |
|
1841 |
GGAACCAGAT |
ACCAGCCATG |
ACCCCAGGCT |
CCACCAAGCA |
TCTTCATGTC |
CCCCTGCTCA |
TCCCCCACTC |
CCCCCCACCC |
|
1921 |
AGAGTTGCTC |
ATCCTGCCAG |
GGCTGGCTGT |
GCCCACCCCA |
AGGCTGCCCT |
CCTGGGGGCC |
CCAGAACTGC |
CTGATCGTGC |
|
2001 |
CGTGGCCCAG |
TTTTGTGGCA |
TCTGCAGCAA |
CACAAGAGAG |
AGGACAATGT |
CCTCCTCTTG |
ACCCGCTGTC |
ACCTAACCAG |
|
2081 |
ACTCGGGCCC |
TGCACCTCTC |
AGGCACTTCT |
GGAAAATGAC |
TGAGGCAGAT |
TCTTCCTGAA |
GCCCATTCTC |
CATGGGGCAA |
|
2161 |
CAAGGACACC |
TATTCTGTCC |
TTGTCCTTCC |
ATCGCTGCCC |
CAGAAAGCCT |
CACATATCTC |
CGTTTAGAAT |
CAGGTCCCTT |
|
2241 |
CTCCCCAGAT |
GAAGAGGAGG |
GTCTCTGCTT |
TGTTTTCTCT |
ATCTCCTCCT |
CAGACTTGAC |
CAGGCCCAGC |
AGGCCCCAGA |
|
2321 |
AGACCATTAC |
CCTATATCCC |
TTCTCCTCCC |
TAGTCACATG |
GCCATAGGCC |
TGCTGATGGC |
TCAGGAAGGC |
CATTGCAAGG |
|
2401 |
ACTCCTCAGC |
TATGGGAGAG |
GAAGCACATC |
ACCCATTGAC |
CCCCGCAACC |
CCTCCCTTTC |
CTCCTCTGAG |
TCCCGACTGG |
|
2481 |
GGCCACATGC |
AGCCTGACTT |
CTTTGTGCCT |
GTTGCTGTCC |
CTGCAGTCTT |
CAGAGGGCCA |
CCGCAGCTCC |
AGTGCCACGG |
|
2561 |
CAGGAGGCTG |
TTCCTGAATA |
GCCCCTGTGG |
TAAGGGCCAG |
GAGAGTCCTT |
CCATCCTCCA |
AGGCCCTGCT |
AAAGGACACA |
|
2641 |
GCAGCCAGGA |
AGTCCCCTGG |
GCCCCTAGCT |
GAAGGACAGC |
CTGCTCCCTC |
CGTCTCTACC |
AGGAATGGCC |
TTGTCCTATG |
|
2721 |
GAAGGCACTG |
CCCCATCCCA |
AACTAATCTA |
GGAATCACTG |
TCTAACCACT |
CACTGTCATG |
AATGTGTACT |
TAAAGGATGA |
|
2801 |
GGTTGAGTCA |
TACCAAATAG |
TGATTTCGAT |
AGTTCAAAAT |
GGTGAAATTA |
GCAATTCTAC |
ATGATTCAGT |
CTAATCAATG |
|
2881 |
GATACCGACT |
GTTTCCCACA |
CAAGTCTCCT |
GTTCTCTTAA |
GCTTACTCAC |
TGACAGCCTT |
TCACTCTCCA |
CAAATACATT |
|
2961 |
AAAGATATGG |
CCATCACCAA |
GCCCCCTAGG |
ATGACACCAG |
ACCTGAGAGT |
CTGAAGACCT |
GGATCCAAGT |
TCTGACTTTT |
|
3041 |
CCCCCTGACA |
GCTGTGTGAC |
CTTCGTGAAG |
TCGCCAAACC |
TCTCTGAGCC |
CCAGTCATTG |
CTAGTAAGAC |
CTGCCTTTGA |
|
3121 |
GTTGGTATGA |
TGTTCAAGTT |
AGATAACAAA |
ATGTTTATAC |
CCATTAGAAC |
AGAGAATAAA |
TAGAACTACA |
TTTCTTGCA |
|
|
|
|
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|
|
>gi|189163525|ref|NM_001002235.2|Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (SERPINA1), transcript variant 3
TGGGCAGGAACTGGGCACTGTGCCCAGGGCATGCACTGCCTCCACGCAGCAACCCTCAGAGTCCTGAGCTGAACCAAGAA
GGAGGAGGGGGTCGGGCCTCCGAGGAAGGCCTAGCCGCTGCTGCTGCCAGGAATTCCAGGTTGGAGGGGCGGCAACCTCC
TGCCAGCCTTCAGGCCACTCTCCTGTGCCTGCCAGAAGAGACAGAGCTTGAGGAGAGCTTGAGGAGAGCAGGAAAGGACA
ATGCCGTCTTCTGTCTCGTGGGGCATCCTCCTGCTGGCAGGCCTGTGCTGCCTGGTCCCTGTCTCCCTGGCTGAGGATCC
CCAGGGAGATGCTGCCCAGAAGACAGATACATCCCACCATGATCAGGATCACCCAACCTTCAACAAGATCACCCCCAACC
TGGCTGAGTTCGCCTTCAGCCTATACCGCCAGCTGGCACACCAGTCCAACAGCACCAATATCTTCTTCTCCCCAGTGAGC
ATCGCTACAGCCTTTGCAATGCTCTCCCTGGGGACCAAGGCTGACACTCACGATGAAATCCTGGAGGGCCTGAATTTCAA
CCTCACGGAGATTCCGGAGGCTCAGATCCATGAAGGCTTCCAGGAACTCCTCCGTACCCTCAACCAGCCAGACAGCCAGC
TCCAGCTGACCACCGGCAATGGCCTGTTCCTCAGCGAGGGCCTGAAGCTAGTGGATAAGTTTTTGGAGGATGTTAAAAAG
TTGTACCACTCAGAAGCCTTCACTGTCAACTTCGGGGACACCGAAGAGGCCAAGAAACAGATCAACGATTACGTGGAGAA
GGGTACTCAAGGGAAAATTGTGGATTTGGTCAAGGAGCTTGACAGAGACACAGTTTTTGCTCTGGTGAATTACATCTTCT
TTAAAGGCAAATGGGAGAGACCCTTTGAAGTCAAGGACACCGAGGAAGAGGACTTCCACGTGGACCAGGTGACCACCGTG
AAGGTGCCTATGATGAAGCGTTTAGGCATGTTTAACATCCAGCACTGTAAGAAGCTGTCCAGCTGGGTGCTGCTGATGAA
ATACCTGGGCAATGCCACCGCCATCTTCTTCCTGCCTGATGAGGGGAAACTACAGCACCTGGAAAATGAACTCACCCACG
ATATCATCACCAAGTTCCTGGAAAATGAAGACAGAAGGTCTGCCAGCTTACATTTACCCAAACTGTCCATTACTGGAACC
TATGATCTGAAGAGCGTCCTGGGTCAACTGGGCATCACTAAGGTCTTCAGCAATGGGGCTGACCTCTCCGGGGTCACAGA
GGAGGCACCCCTGAAGCTCTCCAAGGCCGTGCATAAGGCTGTGCTGACCATCGACGAGAAAGGGACTGAAGCTGCTGGGG
CCATGTTTTTAGAGGCCATACCCATGTCTATCCCCCCCGAGGTCAAGTTCAACAAACCCTTTGTCTTCTTAATGATTGAA
CAAAATACCAAGTCTCCCCTCTTCATGGGAAAAGTGGTGAATCCCACCCAAAAATAACTGCCTCTCGCTCCTCAACCCCT
CCCCTCCATCCCTGGCCCCCTCCCTGGATGACATTAAAGAAGGGTTGAGCTGGTCCCTGCCTGCATGTGACTGTAAATCC
CTCCCATGTTTTCTCTGAGTCTCCCTTTGCCTGCTGAGGCTGTATGTGGGCTCCAGGTAACAGTGCTGTCTTCGGGCCCC
CTGAACTGTGTTCATGGAGCATCTGGCTGGGTAGGCACATGCTGGGCTTGAATCCAGGGGGGACTGAATCCTCAGCTTAC
GGACCTGGGCCCATCTGTTTCTGGAGGGCTCCAGTCTTCCTTGTCCTGTCTTGGAGTCCCCAAGAAGGAATCACAGGGGA
GGAACCAGATACCAGCCATGACCCCAGGCTCCACCAAGCATCTTCATGTCCCCCTGCTCATCCCCCACTCCCCCCCACCC
AGAGTTGCTCATCCTGCCAGGGCTGGCTGTGCCCACCCCAAGGCTGCCCTCCTGGGGGCCCCAGAACTGCCTGATCGTGC
CGTGGCCCAGTTTTGTGGCATCTGCAGCAACACAAGAGAGAGGACAATGTCCTCCTCTTGACCCGCTGTCACCTAACCAG
ACTCGGGCCCTGCACCTCTCAGGCACTTCTGGAAAATGACTGAGGCAGATTCTTCCTGAAGCCCATTCTCCATGGGGCAA
CAAGGACACCTATTCTGTCCTTGTCCTTCCATCGCTGCCCCAGAAAGCCTCACATATCTCCGTTTAGAATCAGGTCCCTT
CTCCCCAGATGAAGAGGAGGGTCTCTGCTTTGTTTTCTCTATCTCCTCCTCAGACTTGACCAGGCCCAGCAGGCCCCAGA
AGACCATTACCCTATATCCCTTCTCCTCCCTAGTCACATGGCCATAGGCCTGCTGATGGCTCAGGAAGGCCATTGCAAGG
ACTCCTCAGCTATGGGAGAGGAAGCACATCACCCATTGACCCCCGCAACCCCTCCCTTTCCTCCTCTGAGTCCCGACTGG
GGCCACATGCAGCCTGACTTCTTTGTGCCTGTTGCTGTCCCTGCAGTCTTCAGAGGGCCACCGCAGCTCCAGTGCCACGG
CAGGAGGCTGTTCCTGAATAGCCCCTGTGGTAAGGGCCAGGAGAGTCCTTCCATCCTCCAAGGCCCTGCTAAAGGACACA
GCAGCCAGGAAGTCCCCTGGGCCCCTAGCTGAAGGACAGCCTGCTCCCTCCGTCTCTACCAGGAATGGCCTTGTCCTATG
GAAGGCACTGCCCCATCCCAAACTAATCTAGGAATCACTGTCTAACCACTCACTGTCATGAATGTGTACTTAAAGGATGA
GGTTGAGTCATACCAAATAGTGATTTCGATAGTTCAAAATGGTGAAATTAGCAATTCTACATGATTCAGTCTAATCAATG
GATACCGACTGTTTCCCACACAAGTCTCCTGTTCTCTTAAGCTTACTCACTGACAGCCTTTCACTCTCCACAAATACATT
AAAGATATGGCCATCACCAAGCCCCCTAGGATGACACCAGACCTGAGAGTCTGAAGACCTGGATCCAAGTTCTGACTTTT
CCCCCTGACAGCTGTGTGACCTTCGTGAAGTCGCCAAACCTCTCTGAGCCCCAGTCATTGCTAGTAAGACCTGCCTTTGA
GTTGGTATGATGTTCAAGTTAGATAACAAAATGTTTATACCCATTAGAACAGAGAATAAATAGAACTACATTTCTTGCA
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| |
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Primary source |
RefSeq : NM_001127700.1 (GI:189163527)
|
Name |
Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (SERPINA1), transcript variant 4
|
Type of transcript |
mRNA
|
Organism |
Homo sapiens
|
Length |
3236 nt
|
Map |
14q32.1
|
Location |
Chromosome 14 (NC_000014.8) strand : -
94843083...94844976 | 94845800...94845947 | 94847207...94847477 | 94848928...94849577 |
94856756...94857028 |
|
|
|
|
|
|
|
|
|
|
|
|
|
Exon(s) |
Start |
End |
Length |
is coding |
Exon 1b
|
1
|
273
|
273
|
1
|
Exon 3
|
274
|
923
|
650
|
1
|
Exon 4
|
924
|
1194
|
271
|
1
|
Exon 5
|
1195
|
1342
|
148
|
1
|
Exon 6
|
1343
|
3236
|
1894
|
1
|
|
|
|
|
|
|
|
|
|
|
|
|
ID |
Class |
Location |
Mutation |
Length |
is synonymous |
Source |
|
|
|
|
|
|
|
|
|
|
|
|
Primary source |
NCBI : CCDS9925
|
Nucleotide |
SERPINA1, mRNA isoform 4[NM_001127700.1] : 278...1534
|
Length |
1257
|
Location |
Chromosome 14 (NC_000014.8) strand : -
94844785...94844976 | 94845800...94845947 | 94847207...94847477 | 94848928...94849573 |
|
Start codon |
1
|
Translation |
NP_001121172.1 |
|
|
|
|
|
|
|
|
|
|
|
|
1 |
TGGGCAGGAA |
CTGGGCACTG |
TGCCCAGGGC |
ATGCACTGCC |
TCCACGCAGC |
AACCCTCAGA |
GTCCTGAGCT |
GAACCAAGAA |
|
81 |
GGAGGAGGGG |
GTCGGGCCTC |
CGAGGAAGGC |
CTAGCCGCTG |
CTGCTGCCAG |
GAATTCCAGG |
TTGGAGGGGC |
GGCAACCTCC |
|
161 |
TGCCAGCCTT |
CAGGCCACTC |
TCCTGTGCCT |
GCCAGAAGAG |
ACAGAGCTTG |
AGGAGAGCTT |
GAGGAGAGCA |
GGAAAGGTGG |
|
241 |
GACATTGCTG |
CTGCTGCTCA |
CTCAGTTCCA |
CAGGACAATG |
CCGTCTTCTG |
TCTCGTGGGG |
CATCCTCCTG |
CTGGCAGGCC |
|
321 |
TGTGCTGCCT |
GGTCCCTGTC |
TCCCTGGCTG |
AGGATCCCCA |
GGGAGATGCT |
GCCCAGAAGA |
CAGATACATC |
CCACCATGAT |
|
401 |
CAGGATCACC |
CAACCTTCAA |
CAAGATCACC |
CCCAACCTGG |
CTGAGTTCGC |
CTTCAGCCTA |
TACCGCCAGC |
TGGCACACCA |
|
481 |
GTCCAACAGC |
ACCAATATCT |
TCTTCTCCCC |
AGTGAGCATC |
GCTACAGCCT |
TTGCAATGCT |
CTCCCTGGGG |
ACCAAGGCTG |
|
561 |
ACACTCACGA |
TGAAATCCTG |
GAGGGCCTGA |
ATTTCAACCT |
CACGGAGATT |
CCGGAGGCTC |
AGATCCATGA |
AGGCTTCCAG |
|
641 |
GAACTCCTCC |
GTACCCTCAA |
CCAGCCAGAC |
AGCCAGCTCC |
AGCTGACCAC |
CGGCAATGGC |
CTGTTCCTCA |
GCGAGGGCCT |
|
721 |
GAAGCTAGTG |
GATAAGTTTT |
TGGAGGATGT |
TAAAAAGTTG |
TACCACTCAG |
AAGCCTTCAC |
TGTCAACTTC |
GGGGACACCG |
|
801 |
AAGAGGCCAA |
GAAACAGATC |
AACGATTACG |
TGGAGAAGGG |
TACTCAAGGG |
AAAATTGTGG |
ATTTGGTCAA |
GGAGCTTGAC |
|
881 |
AGAGACACAG |
TTTTTGCTCT |
GGTGAATTAC |
ATCTTCTTTA |
AAGGCAAATG |
GGAGAGACCC |
TTTGAAGTCA |
AGGACACCGA |
|
961 |
GGAAGAGGAC |
TTCCACGTGG |
ACCAGGTGAC |
CACCGTGAAG |
GTGCCTATGA |
TGAAGCGTTT |
AGGCATGTTT |
AACATCCAGC |
|
1041 |
ACTGTAAGAA |
GCTGTCCAGC |
TGGGTGCTGC |
TGATGAAATA |
CCTGGGCAAT |
GCCACCGCCA |
TCTTCTTCCT |
GCCTGATGAG |
|
1121 |
GGGAAACTAC |
AGCACCTGGA |
AAATGAACTC |
ACCCACGATA |
TCATCACCAA |
GTTCCTGGAA |
AATGAAGACA |
GAAGGTCTGC |
|
1201 |
CAGCTTACAT |
TTACCCAAAC |
TGTCCATTAC |
TGGAACCTAT |
GATCTGAAGA |
GCGTCCTGGG |
TCAACTGGGC |
ATCACTAAGG |
|
1281 |
TCTTCAGCAA |
TGGGGCTGAC |
CTCTCCGGGG |
TCACAGAGGA |
GGCACCCCTG |
AAGCTCTCCA |
AGGCCGTGCA |
TAAGGCTGTG |
|
1361 |
CTGACCATCG |
ACGAGAAAGG |
GACTGAAGCT |
GCTGGGGCCA |
TGTTTTTAGA |
GGCCATACCC |
ATGTCTATCC |
CCCCCGAGGT |
|
1441 |
CAAGTTCAAC |
AAACCCTTTG |
TCTTCTTAAT |
GATTGAACAA |
AATACCAAGT |
CTCCCCTCTT |
CATGGGAAAA |
GTGGTGAATC |
|
1521 |
CCACCCAAAA |
ATAACTGCCT |
CTCGCTCCTC |
AACCCCTCCC |
CTCCATCCCT |
GGCCCCCTCC |
CTGGATGACA |
TTAAAGAAGG |
|
1601 |
GTTGAGCTGG |
TCCCTGCCTG |
CATGTGACTG |
TAAATCCCTC |
CCATGTTTTC |
TCTGAGTCTC |
CCTTTGCCTG |
CTGAGGCTGT |
|
1681 |
ATGTGGGCTC |
CAGGTAACAG |
TGCTGTCTTC |
GGGCCCCCTG |
AACTGTGTTC |
ATGGAGCATC |
TGGCTGGGTA |
GGCACATGCT |
|
1761 |
GGGCTTGAAT |
CCAGGGGGGA |
CTGAATCCTC |
AGCTTACGGA |
CCTGGGCCCA |
TCTGTTTCTG |
GAGGGCTCCA |
GTCTTCCTTG |
|
1841 |
TCCTGTCTTG |
GAGTCCCCAA |
GAAGGAATCA |
CAGGGGAGGA |
ACCAGATACC |
AGCCATGACC |
CCAGGCTCCA |
CCAAGCATCT |
|
1921 |
TCATGTCCCC |
CTGCTCATCC |
CCCACTCCCC |
CCCACCCAGA |
GTTGCTCATC |
CTGCCAGGGC |
TGGCTGTGCC |
CACCCCAAGG |
|
2001 |
CTGCCCTCCT |
GGGGGCCCCA |
GAACTGCCTG |
ATCGTGCCGT |
GGCCCAGTTT |
TGTGGCATCT |
GCAGCAACAC |
AAGAGAGAGG |
|
2081 |
ACAATGTCCT |
CCTCTTGACC |
CGCTGTCACC |
TAACCAGACT |
CGGGCCCTGC |
ACCTCTCAGG |
CACTTCTGGA |
AAATGACTGA |
|
2161 |
GGCAGATTCT |
TCCTGAAGCC |
CATTCTCCAT |
GGGGCAACAA |
GGACACCTAT |
TCTGTCCTTG |
TCCTTCCATC |
GCTGCCCCAG |
|
2241 |
AAAGCCTCAC |
ATATCTCCGT |
TTAGAATCAG |
GTCCCTTCTC |
CCCAGATGAA |
GAGGAGGGTC |
TCTGCTTTGT |
TTTCTCTATC |
|
2321 |
TCCTCCTCAG |
ACTTGACCAG |
GCCCAGCAGG |
CCCCAGAAGA |
CCATTACCCT |
ATATCCCTTC |
TCCTCCCTAG |
TCACATGGCC |
|
2401 |
ATAGGCCTGC |
TGATGGCTCA |
GGAAGGCCAT |
TGCAAGGACT |
CCTCAGCTAT |
GGGAGAGGAA |
GCACATCACC |
CATTGACCCC |
|
2481 |
CGCAACCCCT |
CCCTTTCCTC |
CTCTGAGTCC |
CGACTGGGGC |
CACATGCAGC |
CTGACTTCTT |
TGTGCCTGTT |
GCTGTCCCTG |
|
2561 |
CAGTCTTCAG |
AGGGCCACCG |
CAGCTCCAGT |
GCCACGGCAG |
GAGGCTGTTC |
CTGAATAGCC |
CCTGTGGTAA |
GGGCCAGGAG |
|
2641 |
AGTCCTTCCA |
TCCTCCAAGG |
CCCTGCTAAA |
GGACACAGCA |
GCCAGGAAGT |
CCCCTGGGCC |
CCTAGCTGAA |
GGACAGCCTG |
|
2721 |
CTCCCTCCGT |
CTCTACCAGG |
AATGGCCTTG |
TCCTATGGAA |
GGCACTGCCC |
CATCCCAAAC |
TAATCTAGGA |
ATCACTGTCT |
|
2801 |
AACCACTCAC |
TGTCATGAAT |
GTGTACTTAA |
AGGATGAGGT |
TGAGTCATAC |
CAAATAGTGA |
TTTCGATAGT |
TCAAAATGGT |
|
2881 |
GAAATTAGCA |
ATTCTACATG |
ATTCAGTCTA |
ATCAATGGAT |
ACCGACTGTT |
TCCCACACAA |
GTCTCCTGTT |
CTCTTAAGCT |
|
2961 |
TACTCACTGA |
CAGCCTTTCA |
CTCTCCACAA |
ATACATTAAA |
GATATGGCCA |
TCACCAAGCC |
CCCTAGGATG |
ACACCAGACC |
|
3041 |
TGAGAGTCTG |
AAGACCTGGA |
TCCAAGTTCT |
GACTTTTCCC |
CCTGACAGCT |
GTGTGACCTT |
CGTGAAGTCG |
CCAAACCTCT |
|
3121 |
CTGAGCCCCA |
GTCATTGCTA |
GTAAGACCTG |
CCTTTGAGTT |
GGTATGATGT |
TCAAGTTAGA |
TAACAAAATG |
TTTATACCCA |
|
3201 |
TTAGAACAGA |
GAATAAATAG |
AACTACATTT |
CTTGCA |
|
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>gi|189163527|ref|NM_001127700.1|Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (SERPINA1), transcript variant 4
TGGGCAGGAACTGGGCACTGTGCCCAGGGCATGCACTGCCTCCACGCAGCAACCCTCAGAGTCCTGAGCTGAACCAAGAA
GGAGGAGGGGGTCGGGCCTCCGAGGAAGGCCTAGCCGCTGCTGCTGCCAGGAATTCCAGGTTGGAGGGGCGGCAACCTCC
TGCCAGCCTTCAGGCCACTCTCCTGTGCCTGCCAGAAGAGACAGAGCTTGAGGAGAGCTTGAGGAGAGCAGGAAAGGTGG
GACATTGCTGCTGCTGCTCACTCAGTTCCACAGGACAATGCCGTCTTCTGTCTCGTGGGGCATCCTCCTGCTGGCAGGCC
TGTGCTGCCTGGTCCCTGTCTCCCTGGCTGAGGATCCCCAGGGAGATGCTGCCCAGAAGACAGATACATCCCACCATGAT
CAGGATCACCCAACCTTCAACAAGATCACCCCCAACCTGGCTGAGTTCGCCTTCAGCCTATACCGCCAGCTGGCACACCA
GTCCAACAGCACCAATATCTTCTTCTCCCCAGTGAGCATCGCTACAGCCTTTGCAATGCTCTCCCTGGGGACCAAGGCTG
ACACTCACGATGAAATCCTGGAGGGCCTGAATTTCAACCTCACGGAGATTCCGGAGGCTCAGATCCATGAAGGCTTCCAG
GAACTCCTCCGTACCCTCAACCAGCCAGACAGCCAGCTCCAGCTGACCACCGGCAATGGCCTGTTCCTCAGCGAGGGCCT
GAAGCTAGTGGATAAGTTTTTGGAGGATGTTAAAAAGTTGTACCACTCAGAAGCCTTCACTGTCAACTTCGGGGACACCG
AAGAGGCCAAGAAACAGATCAACGATTACGTGGAGAAGGGTACTCAAGGGAAAATTGTGGATTTGGTCAAGGAGCTTGAC
AGAGACACAGTTTTTGCTCTGGTGAATTACATCTTCTTTAAAGGCAAATGGGAGAGACCCTTTGAAGTCAAGGACACCGA
GGAAGAGGACTTCCACGTGGACCAGGTGACCACCGTGAAGGTGCCTATGATGAAGCGTTTAGGCATGTTTAACATCCAGC
ACTGTAAGAAGCTGTCCAGCTGGGTGCTGCTGATGAAATACCTGGGCAATGCCACCGCCATCTTCTTCCTGCCTGATGAG
GGGAAACTACAGCACCTGGAAAATGAACTCACCCACGATATCATCACCAAGTTCCTGGAAAATGAAGACAGAAGGTCTGC
CAGCTTACATTTACCCAAACTGTCCATTACTGGAACCTATGATCTGAAGAGCGTCCTGGGTCAACTGGGCATCACTAAGG
TCTTCAGCAATGGGGCTGACCTCTCCGGGGTCACAGAGGAGGCACCCCTGAAGCTCTCCAAGGCCGTGCATAAGGCTGTG
CTGACCATCGACGAGAAAGGGACTGAAGCTGCTGGGGCCATGTTTTTAGAGGCCATACCCATGTCTATCCCCCCCGAGGT
CAAGTTCAACAAACCCTTTGTCTTCTTAATGATTGAACAAAATACCAAGTCTCCCCTCTTCATGGGAAAAGTGGTGAATC
CCACCCAAAAATAACTGCCTCTCGCTCCTCAACCCCTCCCCTCCATCCCTGGCCCCCTCCCTGGATGACATTAAAGAAGG
GTTGAGCTGGTCCCTGCCTGCATGTGACTGTAAATCCCTCCCATGTTTTCTCTGAGTCTCCCTTTGCCTGCTGAGGCTGT
ATGTGGGCTCCAGGTAACAGTGCTGTCTTCGGGCCCCCTGAACTGTGTTCATGGAGCATCTGGCTGGGTAGGCACATGCT
GGGCTTGAATCCAGGGGGGACTGAATCCTCAGCTTACGGACCTGGGCCCATCTGTTTCTGGAGGGCTCCAGTCTTCCTTG
TCCTGTCTTGGAGTCCCCAAGAAGGAATCACAGGGGAGGAACCAGATACCAGCCATGACCCCAGGCTCCACCAAGCATCT
TCATGTCCCCCTGCTCATCCCCCACTCCCCCCCACCCAGAGTTGCTCATCCTGCCAGGGCTGGCTGTGCCCACCCCAAGG
CTGCCCTCCTGGGGGCCCCAGAACTGCCTGATCGTGCCGTGGCCCAGTTTTGTGGCATCTGCAGCAACACAAGAGAGAGG
ACAATGTCCTCCTCTTGACCCGCTGTCACCTAACCAGACTCGGGCCCTGCACCTCTCAGGCACTTCTGGAAAATGACTGA
GGCAGATTCTTCCTGAAGCCCATTCTCCATGGGGCAACAAGGACACCTATTCTGTCCTTGTCCTTCCATCGCTGCCCCAG
AAAGCCTCACATATCTCCGTTTAGAATCAGGTCCCTTCTCCCCAGATGAAGAGGAGGGTCTCTGCTTTGTTTTCTCTATC
TCCTCCTCAGACTTGACCAGGCCCAGCAGGCCCCAGAAGACCATTACCCTATATCCCTTCTCCTCCCTAGTCACATGGCC
ATAGGCCTGCTGATGGCTCAGGAAGGCCATTGCAAGGACTCCTCAGCTATGGGAGAGGAAGCACATCACCCATTGACCCC
CGCAACCCCTCCCTTTCCTCCTCTGAGTCCCGACTGGGGCCACATGCAGCCTGACTTCTTTGTGCCTGTTGCTGTCCCTG
CAGTCTTCAGAGGGCCACCGCAGCTCCAGTGCCACGGCAGGAGGCTGTTCCTGAATAGCCCCTGTGGTAAGGGCCAGGAG
AGTCCTTCCATCCTCCAAGGCCCTGCTAAAGGACACAGCAGCCAGGAAGTCCCCTGGGCCCCTAGCTGAAGGACAGCCTG
CTCCCTCCGTCTCTACCAGGAATGGCCTTGTCCTATGGAAGGCACTGCCCCATCCCAAACTAATCTAGGAATCACTGTCT
AACCACTCACTGTCATGAATGTGTACTTAAAGGATGAGGTTGAGTCATACCAAATAGTGATTTCGATAGTTCAAAATGGT
GAAATTAGCAATTCTACATGATTCAGTCTAATCAATGGATACCGACTGTTTCCCACACAAGTCTCCTGTTCTCTTAAGCT
TACTCACTGACAGCCTTTCACTCTCCACAAATACATTAAAGATATGGCCATCACCAAGCCCCCTAGGATGACACCAGACC
TGAGAGTCTGAAGACCTGGATCCAAGTTCTGACTTTTCCCCCTGACAGCTGTGTGACCTTCGTGAAGTCGCCAAACCTCT
CTGAGCCCCAGTCATTGCTAGTAAGACCTGCCTTTGAGTTGGTATGATGTTCAAGTTAGATAACAAAATGTTTATACCCA
TTAGAACAGAGAATAAATAGAACTACATTTCTTGCA
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Primary source |
RefSeq : NM_001127701.1 (GI:189163529)
|
Name |
Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (SERPINA1), transcript variant 5
|
Type of transcript |
mRNA
|
Organism |
Homo sapiens
|
Length |
3532 nt
|
Map |
14q32.1
|
Location |
Chromosome 14 (NC_000014.8) strand : -
94843083...94844976 | 94845800...94845947 | 94847207...94847477 | 94848928...94849577 |
94854896...94854999 | 94855155...94855346 | 94856756...94857028 |
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|
Exon(s) |
Start |
End |
Length |
is coding |
Exon 1b
|
1
|
273
|
273
|
1
|
Exon 2a
|
274
|
465
|
192
|
1
|
Exon 2d
|
466
|
569
|
104
|
1
|
Exon 3
|
570
|
1219
|
650
|
1
|
Exon 4
|
1220
|
1490
|
271
|
1
|
Exon 5
|
1491
|
1638
|
148
|
1
|
Exon 6
|
1639
|
3532
|
1894
|
1
|
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ID |
Class |
Location |
Mutation |
Length |
is synonymous |
Source |
|
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|
Primary source |
NCBI : CCDS9925
|
Nucleotide |
SERPINA1, mRNA isoform 5[NM_001127701.1] : 574...1830
|
Length |
1257
|
Location |
Chromosome 14 (NC_000014.8) strand : -
94844785...94844976 | 94845800...94845947 | 94847207...94847477 | 94848928...94849573 |
|
Start codon |
1
|
Translation |
NP_001121173.1 |
|
|
|
|
|
|
|
|
|
|
|
|
1 |
TGGGCAGGAA |
CTGGGCACTG |
TGCCCAGGGC |
ATGCACTGCC |
TCCACGCAGC |
AACCCTCAGA |
GTCCTGAGCT |
GAACCAAGAA |
|
81 |
GGAGGAGGGG |
GTCGGGCCTC |
CGAGGAAGGC |
CTAGCCGCTG |
CTGCTGCCAG |
GAATTCCAGG |
TTGGAGGGGC |
GGCAACCTCC |
|
161 |
TGCCAGCCTT |
CAGGCCACTC |
TCCTGTGCCT |
GCCAGAAGAG |
ACAGAGCTTG |
AGGAGAGCTT |
GAGGAGAGCA |
GGAAAGGTGG |
|
241 |
GACATTGCTG |
CTGCTGCTCA |
CTCAGTTCCA |
CAGGGCGGCA |
GTAAGTCTTC |
AGCATCAGGC |
ATTTTGGGGT |
GACTCAGTAA |
|
321 |
ATGGTAGATC |
TTGCTACCAG |
TGGAACAGCC |
ACTAAGGATT |
CTGCAGTGAG |
AGCAGAGGGC |
CAGCTAAGTG |
GTACTCTCCC |
|
401 |
AGAGACTGTC |
TGACTCACGC |
CACCCCCTCC |
ACCTTGGACA |
CAGGACGCTG |
TGGTTTCTGA |
GCCAGCAGCC |
TCCCCCGTTG |
|
481 |
CCCCTCTGGA |
TCCACTGCTT |
AAATACGGAC |
GAGGACAGGG |
CCCTGTCTCC |
TCAGCTTCAG |
GCACCACCAC |
TGACCTGGGA |
|
561 |
CAGTGAATCG |
ACAATGCCGT |
CTTCTGTCTC |
GTGGGGCATC |
CTCCTGCTGG |
CAGGCCTGTG |
CTGCCTGGTC |
CCTGTCTCCC |
|
641 |
TGGCTGAGGA |
TCCCCAGGGA |
GATGCTGCCC |
AGAAGACAGA |
TACATCCCAC |
CATGATCAGG |
ATCACCCAAC |
CTTCAACAAG |
|
721 |
ATCACCCCCA |
ACCTGGCTGA |
GTTCGCCTTC |
AGCCTATACC |
GCCAGCTGGC |
ACACCAGTCC |
AACAGCACCA |
ATATCTTCTT |
|
801 |
CTCCCCAGTG |
AGCATCGCTA |
CAGCCTTTGC |
AATGCTCTCC |
CTGGGGACCA |
AGGCTGACAC |
TCACGATGAA |
ATCCTGGAGG |
|
881 |
GCCTGAATTT |
CAACCTCACG |
GAGATTCCGG |
AGGCTCAGAT |
CCATGAAGGC |
TTCCAGGAAC |
TCCTCCGTAC |
CCTCAACCAG |
|
961 |
CCAGACAGCC |
AGCTCCAGCT |
GACCACCGGC |
AATGGCCTGT |
TCCTCAGCGA |
GGGCCTGAAG |
CTAGTGGATA |
AGTTTTTGGA |
|
1041 |
GGATGTTAAA |
AAGTTGTACC |
ACTCAGAAGC |
CTTCACTGTC |
AACTTCGGGG |
ACACCGAAGA |
GGCCAAGAAA |
CAGATCAACG |
|
1121 |
ATTACGTGGA |
GAAGGGTACT |
CAAGGGAAAA |
TTGTGGATTT |
GGTCAAGGAG |
CTTGACAGAG |
ACACAGTTTT |
TGCTCTGGTG |
|
1201 |
AATTACATCT |
TCTTTAAAGG |
CAAATGGGAG |
AGACCCTTTG |
AAGTCAAGGA |
CACCGAGGAA |
GAGGACTTCC |
ACGTGGACCA |
|
1281 |
GGTGACCACC |
GTGAAGGTGC |
CTATGATGAA |
GCGTTTAGGC |
ATGTTTAACA |
TCCAGCACTG |
TAAGAAGCTG |
TCCAGCTGGG |
|
1361 |
TGCTGCTGAT |
GAAATACCTG |
GGCAATGCCA |
CCGCCATCTT |
CTTCCTGCCT |
GATGAGGGGA |
AACTACAGCA |
CCTGGAAAAT |
|
1441 |
GAACTCACCC |
ACGATATCAT |
CACCAAGTTC |
CTGGAAAATG |
AAGACAGAAG |
GTCTGCCAGC |
TTACATTTAC |
CCAAACTGTC |
|
1521 |
CATTACTGGA |
ACCTATGATC |
TGAAGAGCGT |
CCTGGGTCAA |
CTGGGCATCA |
CTAAGGTCTT |
CAGCAATGGG |
GCTGACCTCT |
|
1601 |
CCGGGGTCAC |
AGAGGAGGCA |
CCCCTGAAGC |
TCTCCAAGGC |
CGTGCATAAG |
GCTGTGCTGA |
CCATCGACGA |
GAAAGGGACT |
|
1681 |
GAAGCTGCTG |
GGGCCATGTT |
TTTAGAGGCC |
ATACCCATGT |
CTATCCCCCC |
CGAGGTCAAG |
TTCAACAAAC |
CCTTTGTCTT |
|
1761 |
CTTAATGATT |
GAACAAAATA |
CCAAGTCTCC |
CCTCTTCATG |
GGAAAAGTGG |
TGAATCCCAC |
CCAAAAATAA |
CTGCCTCTCG |
|
1841 |
CTCCTCAACC |
CCTCCCCTCC |
ATCCCTGGCC |
CCCTCCCTGG |
ATGACATTAA |
AGAAGGGTTG |
AGCTGGTCCC |
TGCCTGCATG |
|
1921 |
TGACTGTAAA |
TCCCTCCCAT |
GTTTTCTCTG |
AGTCTCCCTT |
TGCCTGCTGA |
GGCTGTATGT |
GGGCTCCAGG |
TAACAGTGCT |
|
2001 |
GTCTTCGGGC |
CCCCTGAACT |
GTGTTCATGG |
AGCATCTGGC |
TGGGTAGGCA |
CATGCTGGGC |
TTGAATCCAG |
GGGGGACTGA |
|
2081 |
ATCCTCAGCT |
TACGGACCTG |
GGCCCATCTG |
TTTCTGGAGG |
GCTCCAGTCT |
TCCTTGTCCT |
GTCTTGGAGT |
CCCCAAGAAG |
|
2161 |
GAATCACAGG |
GGAGGAACCA |
GATACCAGCC |
ATGACCCCAG |
GCTCCACCAA |
GCATCTTCAT |
GTCCCCCTGC |
TCATCCCCCA |
|
2241 |
CTCCCCCCCA |
CCCAGAGTTG |
CTCATCCTGC |
CAGGGCTGGC |
TGTGCCCACC |
CCAAGGCTGC |
CCTCCTGGGG |
GCCCCAGAAC |
|
2321 |
TGCCTGATCG |
TGCCGTGGCC |
CAGTTTTGTG |
GCATCTGCAG |
CAACACAAGA |
GAGAGGACAA |
TGTCCTCCTC |
TTGACCCGCT |
|
2401 |
GTCACCTAAC |
CAGACTCGGG |
CCCTGCACCT |
CTCAGGCACT |
TCTGGAAAAT |
GACTGAGGCA |
GATTCTTCCT |
GAAGCCCATT |
|
2481 |
CTCCATGGGG |
CAACAAGGAC |
ACCTATTCTG |
TCCTTGTCCT |
TCCATCGCTG |
CCCCAGAAAG |
CCTCACATAT |
CTCCGTTTAG |
|
2561 |
AATCAGGTCC |
CTTCTCCCCA |
GATGAAGAGG |
AGGGTCTCTG |
CTTTGTTTTC |
TCTATCTCCT |
CCTCAGACTT |
GACCAGGCCC |
|
2641 |
AGCAGGCCCC |
AGAAGACCAT |
TACCCTATAT |
CCCTTCTCCT |
CCCTAGTCAC |
ATGGCCATAG |
GCCTGCTGAT |
GGCTCAGGAA |
|
2721 |
GGCCATTGCA |
AGGACTCCTC |
AGCTATGGGA |
GAGGAAGCAC |
ATCACCCATT |
GACCCCCGCA |
ACCCCTCCCT |
TTCCTCCTCT |
|
2801 |
GAGTCCCGAC |
TGGGGCCACA |
TGCAGCCTGA |
CTTCTTTGTG |
CCTGTTGCTG |
TCCCTGCAGT |
CTTCAGAGGG |
CCACCGCAGC |
|
2881 |
TCCAGTGCCA |
CGGCAGGAGG |
CTGTTCCTGA |
ATAGCCCCTG |
TGGTAAGGGC |
CAGGAGAGTC |
CTTCCATCCT |
CCAAGGCCCT |
|
2961 |
GCTAAAGGAC |
ACAGCAGCCA |
GGAAGTCCCC |
TGGGCCCCTA |
GCTGAAGGAC |
AGCCTGCTCC |
CTCCGTCTCT |
ACCAGGAATG |
|
3041 |
GCCTTGTCCT |
ATGGAAGGCA |
CTGCCCCATC |
CCAAACTAAT |
CTAGGAATCA |
CTGTCTAACC |
ACTCACTGTC |
ATGAATGTGT |
|
3121 |
ACTTAAAGGA |
TGAGGTTGAG |
TCATACCAAA |
TAGTGATTTC |
GATAGTTCAA |
AATGGTGAAA |
TTAGCAATTC |
TACATGATTC |
|
3201 |
AGTCTAATCA |
ATGGATACCG |
ACTGTTTCCC |
ACACAAGTCT |
CCTGTTCTCT |
TAAGCTTACT |
CACTGACAGC |
CTTTCACTCT |
|
3281 |
CCACAAATAC |
ATTAAAGATA |
TGGCCATCAC |
CAAGCCCCCT |
AGGATGACAC |
CAGACCTGAG |
AGTCTGAAGA |
CCTGGATCCA |
|
3361 |
AGTTCTGACT |
TTTCCCCCTG |
ACAGCTGTGT |
GACCTTCGTG |
AAGTCGCCAA |
ACCTCTCTGA |
GCCCCAGTCA |
TTGCTAGTAA |
|
3441 |
GACCTGCCTT |
TGAGTTGGTA |
TGATGTTCAA |
GTTAGATAAC |
AAAATGTTTA |
TACCCATTAG |
AACAGAGAAT |
AAATAGAACT |
|
3521 |
ACATTTCTTG |
CA |
|
|
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>gi|189163529|ref|NM_001127701.1|Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (SERPINA1), transcript variant 5
TGGGCAGGAACTGGGCACTGTGCCCAGGGCATGCACTGCCTCCACGCAGCAACCCTCAGAGTCCTGAGCTGAACCAAGAA
GGAGGAGGGGGTCGGGCCTCCGAGGAAGGCCTAGCCGCTGCTGCTGCCAGGAATTCCAGGTTGGAGGGGCGGCAACCTCC
TGCCAGCCTTCAGGCCACTCTCCTGTGCCTGCCAGAAGAGACAGAGCTTGAGGAGAGCTTGAGGAGAGCAGGAAAGGTGG
GACATTGCTGCTGCTGCTCACTCAGTTCCACAGGGCGGCAGTAAGTCTTCAGCATCAGGCATTTTGGGGTGACTCAGTAA
ATGGTAGATCTTGCTACCAGTGGAACAGCCACTAAGGATTCTGCAGTGAGAGCAGAGGGCCAGCTAAGTGGTACTCTCCC
AGAGACTGTCTGACTCACGCCACCCCCTCCACCTTGGACACAGGACGCTGTGGTTTCTGAGCCAGCAGCCTCCCCCGTTG
CCCCTCTGGATCCACTGCTTAAATACGGACGAGGACAGGGCCCTGTCTCCTCAGCTTCAGGCACCACCACTGACCTGGGA
CAGTGAATCGACAATGCCGTCTTCTGTCTCGTGGGGCATCCTCCTGCTGGCAGGCCTGTGCTGCCTGGTCCCTGTCTCCC
TGGCTGAGGATCCCCAGGGAGATGCTGCCCAGAAGACAGATACATCCCACCATGATCAGGATCACCCAACCTTCAACAAG
ATCACCCCCAACCTGGCTGAGTTCGCCTTCAGCCTATACCGCCAGCTGGCACACCAGTCCAACAGCACCAATATCTTCTT
CTCCCCAGTGAGCATCGCTACAGCCTTTGCAATGCTCTCCCTGGGGACCAAGGCTGACACTCACGATGAAATCCTGGAGG
GCCTGAATTTCAACCTCACGGAGATTCCGGAGGCTCAGATCCATGAAGGCTTCCAGGAACTCCTCCGTACCCTCAACCAG
CCAGACAGCCAGCTCCAGCTGACCACCGGCAATGGCCTGTTCCTCAGCGAGGGCCTGAAGCTAGTGGATAAGTTTTTGGA
GGATGTTAAAAAGTTGTACCACTCAGAAGCCTTCACTGTCAACTTCGGGGACACCGAAGAGGCCAAGAAACAGATCAACG
ATTACGTGGAGAAGGGTACTCAAGGGAAAATTGTGGATTTGGTCAAGGAGCTTGACAGAGACACAGTTTTTGCTCTGGTG
AATTACATCTTCTTTAAAGGCAAATGGGAGAGACCCTTTGAAGTCAAGGACACCGAGGAAGAGGACTTCCACGTGGACCA
GGTGACCACCGTGAAGGTGCCTATGATGAAGCGTTTAGGCATGTTTAACATCCAGCACTGTAAGAAGCTGTCCAGCTGGG
TGCTGCTGATGAAATACCTGGGCAATGCCACCGCCATCTTCTTCCTGCCTGATGAGGGGAAACTACAGCACCTGGAAAAT
GAACTCACCCACGATATCATCACCAAGTTCCTGGAAAATGAAGACAGAAGGTCTGCCAGCTTACATTTACCCAAACTGTC
CATTACTGGAACCTATGATCTGAAGAGCGTCCTGGGTCAACTGGGCATCACTAAGGTCTTCAGCAATGGGGCTGACCTCT
CCGGGGTCACAGAGGAGGCACCCCTGAAGCTCTCCAAGGCCGTGCATAAGGCTGTGCTGACCATCGACGAGAAAGGGACT
GAAGCTGCTGGGGCCATGTTTTTAGAGGCCATACCCATGTCTATCCCCCCCGAGGTCAAGTTCAACAAACCCTTTGTCTT
CTTAATGATTGAACAAAATACCAAGTCTCCCCTCTTCATGGGAAAAGTGGTGAATCCCACCCAAAAATAACTGCCTCTCG
CTCCTCAACCCCTCCCCTCCATCCCTGGCCCCCTCCCTGGATGACATTAAAGAAGGGTTGAGCTGGTCCCTGCCTGCATG
TGACTGTAAATCCCTCCCATGTTTTCTCTGAGTCTCCCTTTGCCTGCTGAGGCTGTATGTGGGCTCCAGGTAACAGTGCT
GTCTTCGGGCCCCCTGAACTGTGTTCATGGAGCATCTGGCTGGGTAGGCACATGCTGGGCTTGAATCCAGGGGGGACTGA
ATCCTCAGCTTACGGACCTGGGCCCATCTGTTTCTGGAGGGCTCCAGTCTTCCTTGTCCTGTCTTGGAGTCCCCAAGAAG
GAATCACAGGGGAGGAACCAGATACCAGCCATGACCCCAGGCTCCACCAAGCATCTTCATGTCCCCCTGCTCATCCCCCA
CTCCCCCCCACCCAGAGTTGCTCATCCTGCCAGGGCTGGCTGTGCCCACCCCAAGGCTGCCCTCCTGGGGGCCCCAGAAC
TGCCTGATCGTGCCGTGGCCCAGTTTTGTGGCATCTGCAGCAACACAAGAGAGAGGACAATGTCCTCCTCTTGACCCGCT
GTCACCTAACCAGACTCGGGCCCTGCACCTCTCAGGCACTTCTGGAAAATGACTGAGGCAGATTCTTCCTGAAGCCCATT
CTCCATGGGGCAACAAGGACACCTATTCTGTCCTTGTCCTTCCATCGCTGCCCCAGAAAGCCTCACATATCTCCGTTTAG
AATCAGGTCCCTTCTCCCCAGATGAAGAGGAGGGTCTCTGCTTTGTTTTCTCTATCTCCTCCTCAGACTTGACCAGGCCC
AGCAGGCCCCAGAAGACCATTACCCTATATCCCTTCTCCTCCCTAGTCACATGGCCATAGGCCTGCTGATGGCTCAGGAA
GGCCATTGCAAGGACTCCTCAGCTATGGGAGAGGAAGCACATCACCCATTGACCCCCGCAACCCCTCCCTTTCCTCCTCT
GAGTCCCGACTGGGGCCACATGCAGCCTGACTTCTTTGTGCCTGTTGCTGTCCCTGCAGTCTTCAGAGGGCCACCGCAGC
TCCAGTGCCACGGCAGGAGGCTGTTCCTGAATAGCCCCTGTGGTAAGGGCCAGGAGAGTCCTTCCATCCTCCAAGGCCCT
GCTAAAGGACACAGCAGCCAGGAAGTCCCCTGGGCCCCTAGCTGAAGGACAGCCTGCTCCCTCCGTCTCTACCAGGAATG
GCCTTGTCCTATGGAAGGCACTGCCCCATCCCAAACTAATCTAGGAATCACTGTCTAACCACTCACTGTCATGAATGTGT
ACTTAAAGGATGAGGTTGAGTCATACCAAATAGTGATTTCGATAGTTCAAAATGGTGAAATTAGCAATTCTACATGATTC
AGTCTAATCAATGGATACCGACTGTTTCCCACACAAGTCTCCTGTTCTCTTAAGCTTACTCACTGACAGCCTTTCACTCT
CCACAAATACATTAAAGATATGGCCATCACCAAGCCCCCTAGGATGACACCAGACCTGAGAGTCTGAAGACCTGGATCCA
AGTTCTGACTTTTCCCCCTGACAGCTGTGTGACCTTCGTGAAGTCGCCAAACCTCTCTGAGCCCCAGTCATTGCTAGTAA
GACCTGCCTTTGAGTTGGTATGATGTTCAAGTTAGATAACAAAATGTTTATACCCATTAGAACAGAGAATAAATAGAACT
ACATTTCTTGCA
|
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| |
|
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|
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|
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|
Primary source |
RefSeq : NM_001127702.1 (GI:189163531)
|
Name |
Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (SERPINA1), transcript variant 6
|
Type of transcript |
mRNA
|
Organism |
Homo sapiens
|
Length |
3340 nt
|
Map |
14q32.1
|
Location |
Chromosome 14 (NC_000014.8) strand : -
94843083...94844976 | 94845800...94845947 | 94847207...94847477 | 94848928...94849577 |
94854896...94854999 | 94856756...94857028 |
|
|
|
|
|
|
|
|
|
|
|
|
|
Exon(s) |
Start |
End |
Length |
is coding |
Exon 1b
|
1
|
273
|
273
|
1
|
Exon 2d
|
274
|
377
|
104
|
1
|
Exon 3
|
378
|
1027
|
650
|
1
|
Exon 4
|
1028
|
1298
|
271
|
1
|
Exon 5
|
1299
|
1446
|
148
|
1
|
Exon 6
|
1447
|
3340
|
1894
|
1
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Primary source |
NCBI : CCDS9925
|
Nucleotide |
SERPINA1, mRNA isoform 6[NM_001127702.1] : 382...1638
|
Length |
1257
|
Location |
Chromosome 14 (NC_000014.8) strand : -
94844785...94844976 | 94845800...94845947 | 94847207...94847477 | 94848928...94849573 |
|
Start codon |
1
|
Translation |
NP_001121174.1 |
|
|
|
|
|
|
|
|
|
|
|
|
1 |
TGGGCAGGAA |
CTGGGCACTG |
TGCCCAGGGC |
ATGCACTGCC |
TCCACGCAGC |
AACCCTCAGA |
GTCCTGAGCT |
GAACCAAGAA |
|
81 |
GGAGGAGGGG |
GTCGGGCCTC |
CGAGGAAGGC |
CTAGCCGCTG |
CTGCTGCCAG |
GAATTCCAGG |
TTGGAGGGGC |
GGCAACCTCC |
|
161 |
TGCCAGCCTT |
CAGGCCACTC |
TCCTGTGCCT |
GCCAGAAGAG |
ACAGAGCTTG |
AGGAGAGCTT |
GAGGAGAGCA |
GGAAAGGTGG |
|
241 |
GACATTGCTG |
CTGCTGCTCA |
CTCAGTTCCA |
CAGCAGCCTC |
CCCCGTTGCC |
CCTCTGGATC |
CACTGCTTAA |
ATACGGACGA |
|
321 |
GGACAGGGCC |
CTGTCTCCTC |
AGCTTCAGGC |
ACCACCACTG |
ACCTGGGACA |
GTGAATCGAC |
AATGCCGTCT |
TCTGTCTCGT |
|
401 |
GGGGCATCCT |
CCTGCTGGCA |
GGCCTGTGCT |
GCCTGGTCCC |
TGTCTCCCTG |
GCTGAGGATC |
CCCAGGGAGA |
TGCTGCCCAG |
|
481 |
AAGACAGATA |
CATCCCACCA |
TGATCAGGAT |
CACCCAACCT |
TCAACAAGAT |
CACCCCCAAC |
CTGGCTGAGT |
TCGCCTTCAG |
|
561 |
CCTATACCGC |
CAGCTGGCAC |
ACCAGTCCAA |
CAGCACCAAT |
ATCTTCTTCT |
CCCCAGTGAG |
CATCGCTACA |
GCCTTTGCAA |
|
641 |
TGCTCTCCCT |
GGGGACCAAG |
GCTGACACTC |
ACGATGAAAT |
CCTGGAGGGC |
CTGAATTTCA |
ACCTCACGGA |
GATTCCGGAG |
|
721 |
GCTCAGATCC |
ATGAAGGCTT |
CCAGGAACTC |
CTCCGTACCC |
TCAACCAGCC |
AGACAGCCAG |
CTCCAGCTGA |
CCACCGGCAA |
|
801 |
TGGCCTGTTC |
CTCAGCGAGG |
GCCTGAAGCT |
AGTGGATAAG |
TTTTTGGAGG |
ATGTTAAAAA |
GTTGTACCAC |
TCAGAAGCCT |
|
881 |
TCACTGTCAA |
CTTCGGGGAC |
ACCGAAGAGG |
CCAAGAAACA |
GATCAACGAT |
TACGTGGAGA |
AGGGTACTCA |
AGGGAAAATT |
|
961 |
GTGGATTTGG |
TCAAGGAGCT |
TGACAGAGAC |
ACAGTTTTTG |
CTCTGGTGAA |
TTACATCTTC |
TTTAAAGGCA |
AATGGGAGAG |
|
1041 |
ACCCTTTGAA |
GTCAAGGACA |
CCGAGGAAGA |
GGACTTCCAC |
GTGGACCAGG |
TGACCACCGT |
GAAGGTGCCT |
ATGATGAAGC |
|
1121 |
GTTTAGGCAT |
GTTTAACATC |
CAGCACTGTA |
AGAAGCTGTC |
CAGCTGGGTG |
CTGCTGATGA |
AATACCTGGG |
CAATGCCACC |
|
1201 |
GCCATCTTCT |
TCCTGCCTGA |
TGAGGGGAAA |
CTACAGCACC |
TGGAAAATGA |
ACTCACCCAC |
GATATCATCA |
CCAAGTTCCT |
|
1281 |
GGAAAATGAA |
GACAGAAGGT |
CTGCCAGCTT |
ACATTTACCC |
AAACTGTCCA |
TTACTGGAAC |
CTATGATCTG |
AAGAGCGTCC |
|
1361 |
TGGGTCAACT |
GGGCATCACT |
AAGGTCTTCA |
GCAATGGGGC |
TGACCTCTCC |
GGGGTCACAG |
AGGAGGCACC |
CCTGAAGCTC |
|
1441 |
TCCAAGGCCG |
TGCATAAGGC |
TGTGCTGACC |
ATCGACGAGA |
AAGGGACTGA |
AGCTGCTGGG |
GCCATGTTTT |
TAGAGGCCAT |
|
1521 |
ACCCATGTCT |
ATCCCCCCCG |
AGGTCAAGTT |
CAACAAACCC |
TTTGTCTTCT |
TAATGATTGA |
ACAAAATACC |
AAGTCTCCCC |
|
1601 |
TCTTCATGGG |
AAAAGTGGTG |
AATCCCACCC |
AAAAATAACT |
GCCTCTCGCT |
CCTCAACCCC |
TCCCCTCCAT |
CCCTGGCCCC |
|
1681 |
CTCCCTGGAT |
GACATTAAAG |
AAGGGTTGAG |
CTGGTCCCTG |
CCTGCATGTG |
ACTGTAAATC |
CCTCCCATGT |
TTTCTCTGAG |
|
1761 |
TCTCCCTTTG |
CCTGCTGAGG |
CTGTATGTGG |
GCTCCAGGTA |
ACAGTGCTGT |
CTTCGGGCCC |
CCTGAACTGT |
GTTCATGGAG |
|
1841 |
CATCTGGCTG |
GGTAGGCACA |
TGCTGGGCTT |
GAATCCAGGG |
GGGACTGAAT |
CCTCAGCTTA |
CGGACCTGGG |
CCCATCTGTT |
|
1921 |
TCTGGAGGGC |
TCCAGTCTTC |
CTTGTCCTGT |
CTTGGAGTCC |
CCAAGAAGGA |
ATCACAGGGG |
AGGAACCAGA |
TACCAGCCAT |
|
2001 |
GACCCCAGGC |
TCCACCAAGC |
ATCTTCATGT |
CCCCCTGCTC |
ATCCCCCACT |
CCCCCCCACC |
CAGAGTTGCT |
CATCCTGCCA |
|
2081 |
GGGCTGGCTG |
TGCCCACCCC |
AAGGCTGCCC |
TCCTGGGGGC |
CCCAGAACTG |
CCTGATCGTG |
CCGTGGCCCA |
GTTTTGTGGC |
|
2161 |
ATCTGCAGCA |
ACACAAGAGA |
GAGGACAATG |
TCCTCCTCTT |
GACCCGCTGT |
CACCTAACCA |
GACTCGGGCC |
CTGCACCTCT |
|
2241 |
CAGGCACTTC |
TGGAAAATGA |
CTGAGGCAGA |
TTCTTCCTGA |
AGCCCATTCT |
CCATGGGGCA |
ACAAGGACAC |
CTATTCTGTC |
|
2321 |
CTTGTCCTTC |
CATCGCTGCC |
CCAGAAAGCC |
TCACATATCT |
CCGTTTAGAA |
TCAGGTCCCT |
TCTCCCCAGA |
TGAAGAGGAG |
|
2401 |
GGTCTCTGCT |
TTGTTTTCTC |
TATCTCCTCC |
TCAGACTTGA |
CCAGGCCCAG |
CAGGCCCCAG |
AAGACCATTA |
CCCTATATCC |
|
2481 |
CTTCTCCTCC |
CTAGTCACAT |
GGCCATAGGC |
CTGCTGATGG |
CTCAGGAAGG |
CCATTGCAAG |
GACTCCTCAG |
CTATGGGAGA |
|
2561 |
GGAAGCACAT |
CACCCATTGA |
CCCCCGCAAC |
CCCTCCCTTT |
CCTCCTCTGA |
GTCCCGACTG |
GGGCCACATG |
CAGCCTGACT |
|
2641 |
TCTTTGTGCC |
TGTTGCTGTC |
CCTGCAGTCT |
TCAGAGGGCC |
ACCGCAGCTC |
CAGTGCCACG |
GCAGGAGGCT |
GTTCCTGAAT |
|
2721 |
AGCCCCTGTG |
GTAAGGGCCA |
GGAGAGTCCT |
TCCATCCTCC |
AAGGCCCTGC |
TAAAGGACAC |
AGCAGCCAGG |
AAGTCCCCTG |
|
2801 |
GGCCCCTAGC |
TGAAGGACAG |
CCTGCTCCCT |
CCGTCTCTAC |
CAGGAATGGC |
CTTGTCCTAT |
GGAAGGCACT |
GCCCCATCCC |
|
2881 |
AAACTAATCT |
AGGAATCACT |
GTCTAACCAC |
TCACTGTCAT |
GAATGTGTAC |
TTAAAGGATG |
AGGTTGAGTC |
ATACCAAATA |
|
2961 |
GTGATTTCGA |
TAGTTCAAAA |
TGGTGAAATT |
AGCAATTCTA |
CATGATTCAG |
TCTAATCAAT |
GGATACCGAC |
TGTTTCCCAC |
|
3041 |
ACAAGTCTCC |
TGTTCTCTTA |
AGCTTACTCA |
CTGACAGCCT |
TTCACTCTCC |
ACAAATACAT |
TAAAGATATG |
GCCATCACCA |
|
3121 |
AGCCCCCTAG |
GATGACACCA |
GACCTGAGAG |
TCTGAAGACC |
TGGATCCAAG |
TTCTGACTTT |
TCCCCCTGAC |
AGCTGTGTGA |
|
3201 |
CCTTCGTGAA |
GTCGCCAAAC |
CTCTCTGAGC |
CCCAGTCATT |
GCTAGTAAGA |
CCTGCCTTTG |
AGTTGGTATG |
ATGTTCAAGT |
|
3281 |
TAGATAACAA |
AATGTTTATA |
CCCATTAGAA |
CAGAGAATAA |
ATAGAACTAC |
ATTTCTTGCA |
|
|
|
|
|
|
|
|
|
|
|
|
>gi|189163531|ref|NM_001127702.1|Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (SERPINA1), transcript variant 6
TGGGCAGGAACTGGGCACTGTGCCCAGGGCATGCACTGCCTCCACGCAGCAACCCTCAGAGTCCTGAGCTGAACCAAGAA
GGAGGAGGGGGTCGGGCCTCCGAGGAAGGCCTAGCCGCTGCTGCTGCCAGGAATTCCAGGTTGGAGGGGCGGCAACCTCC
TGCCAGCCTTCAGGCCACTCTCCTGTGCCTGCCAGAAGAGACAGAGCTTGAGGAGAGCTTGAGGAGAGCAGGAAAGGTGG
GACATTGCTGCTGCTGCTCACTCAGTTCCACAGCAGCCTCCCCCGTTGCCCCTCTGGATCCACTGCTTAAATACGGACGA
GGACAGGGCCCTGTCTCCTCAGCTTCAGGCACCACCACTGACCTGGGACAGTGAATCGACAATGCCGTCTTCTGTCTCGT
GGGGCATCCTCCTGCTGGCAGGCCTGTGCTGCCTGGTCCCTGTCTCCCTGGCTGAGGATCCCCAGGGAGATGCTGCCCAG
AAGACAGATACATCCCACCATGATCAGGATCACCCAACCTTCAACAAGATCACCCCCAACCTGGCTGAGTTCGCCTTCAG
CCTATACCGCCAGCTGGCACACCAGTCCAACAGCACCAATATCTTCTTCTCCCCAGTGAGCATCGCTACAGCCTTTGCAA
TGCTCTCCCTGGGGACCAAGGCTGACACTCACGATGAAATCCTGGAGGGCCTGAATTTCAACCTCACGGAGATTCCGGAG
GCTCAGATCCATGAAGGCTTCCAGGAACTCCTCCGTACCCTCAACCAGCCAGACAGCCAGCTCCAGCTGACCACCGGCAA
TGGCCTGTTCCTCAGCGAGGGCCTGAAGCTAGTGGATAAGTTTTTGGAGGATGTTAAAAAGTTGTACCACTCAGAAGCCT
TCACTGTCAACTTCGGGGACACCGAAGAGGCCAAGAAACAGATCAACGATTACGTGGAGAAGGGTACTCAAGGGAAAATT
GTGGATTTGGTCAAGGAGCTTGACAGAGACACAGTTTTTGCTCTGGTGAATTACATCTTCTTTAAAGGCAAATGGGAGAG
ACCCTTTGAAGTCAAGGACACCGAGGAAGAGGACTTCCACGTGGACCAGGTGACCACCGTGAAGGTGCCTATGATGAAGC
GTTTAGGCATGTTTAACATCCAGCACTGTAAGAAGCTGTCCAGCTGGGTGCTGCTGATGAAATACCTGGGCAATGCCACC
GCCATCTTCTTCCTGCCTGATGAGGGGAAACTACAGCACCTGGAAAATGAACTCACCCACGATATCATCACCAAGTTCCT
GGAAAATGAAGACAGAAGGTCTGCCAGCTTACATTTACCCAAACTGTCCATTACTGGAACCTATGATCTGAAGAGCGTCC
TGGGTCAACTGGGCATCACTAAGGTCTTCAGCAATGGGGCTGACCTCTCCGGGGTCACAGAGGAGGCACCCCTGAAGCTC
TCCAAGGCCGTGCATAAGGCTGTGCTGACCATCGACGAGAAAGGGACTGAAGCTGCTGGGGCCATGTTTTTAGAGGCCAT
ACCCATGTCTATCCCCCCCGAGGTCAAGTTCAACAAACCCTTTGTCTTCTTAATGATTGAACAAAATACCAAGTCTCCCC
TCTTCATGGGAAAAGTGGTGAATCCCACCCAAAAATAACTGCCTCTCGCTCCTCAACCCCTCCCCTCCATCCCTGGCCCC
CTCCCTGGATGACATTAAAGAAGGGTTGAGCTGGTCCCTGCCTGCATGTGACTGTAAATCCCTCCCATGTTTTCTCTGAG
TCTCCCTTTGCCTGCTGAGGCTGTATGTGGGCTCCAGGTAACAGTGCTGTCTTCGGGCCCCCTGAACTGTGTTCATGGAG
CATCTGGCTGGGTAGGCACATGCTGGGCTTGAATCCAGGGGGGACTGAATCCTCAGCTTACGGACCTGGGCCCATCTGTT
TCTGGAGGGCTCCAGTCTTCCTTGTCCTGTCTTGGAGTCCCCAAGAAGGAATCACAGGGGAGGAACCAGATACCAGCCAT
GACCCCAGGCTCCACCAAGCATCTTCATGTCCCCCTGCTCATCCCCCACTCCCCCCCACCCAGAGTTGCTCATCCTGCCA
GGGCTGGCTGTGCCCACCCCAAGGCTGCCCTCCTGGGGGCCCCAGAACTGCCTGATCGTGCCGTGGCCCAGTTTTGTGGC
ATCTGCAGCAACACAAGAGAGAGGACAATGTCCTCCTCTTGACCCGCTGTCACCTAACCAGACTCGGGCCCTGCACCTCT
CAGGCACTTCTGGAAAATGACTGAGGCAGATTCTTCCTGAAGCCCATTCTCCATGGGGCAACAAGGACACCTATTCTGTC
CTTGTCCTTCCATCGCTGCCCCAGAAAGCCTCACATATCTCCGTTTAGAATCAGGTCCCTTCTCCCCAGATGAAGAGGAG
GGTCTCTGCTTTGTTTTCTCTATCTCCTCCTCAGACTTGACCAGGCCCAGCAGGCCCCAGAAGACCATTACCCTATATCC
CTTCTCCTCCCTAGTCACATGGCCATAGGCCTGCTGATGGCTCAGGAAGGCCATTGCAAGGACTCCTCAGCTATGGGAGA
GGAAGCACATCACCCATTGACCCCCGCAACCCCTCCCTTTCCTCCTCTGAGTCCCGACTGGGGCCACATGCAGCCTGACT
TCTTTGTGCCTGTTGCTGTCCCTGCAGTCTTCAGAGGGCCACCGCAGCTCCAGTGCCACGGCAGGAGGCTGTTCCTGAAT
AGCCCCTGTGGTAAGGGCCAGGAGAGTCCTTCCATCCTCCAAGGCCCTGCTAAAGGACACAGCAGCCAGGAAGTCCCCTG
GGCCCCTAGCTGAAGGACAGCCTGCTCCCTCCGTCTCTACCAGGAATGGCCTTGTCCTATGGAAGGCACTGCCCCATCCC
AAACTAATCTAGGAATCACTGTCTAACCACTCACTGTCATGAATGTGTACTTAAAGGATGAGGTTGAGTCATACCAAATA
GTGATTTCGATAGTTCAAAATGGTGAAATTAGCAATTCTACATGATTCAGTCTAATCAATGGATACCGACTGTTTCCCAC
ACAAGTCTCCTGTTCTCTTAAGCTTACTCACTGACAGCCTTTCACTCTCCACAAATACATTAAAGATATGGCCATCACCA
AGCCCCCTAGGATGACACCAGACCTGAGAGTCTGAAGACCTGGATCCAAGTTCTGACTTTTCCCCCTGACAGCTGTGTGA
CCTTCGTGAAGTCGCCAAACCTCTCTGAGCCCCAGTCATTGCTAGTAAGACCTGCCTTTGAGTTGGTATGATGTTCAAGT
TAGATAACAAAATGTTTATACCCATTAGAACAGAGAATAAATAGAACTACATTTCTTGCA
|
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| |
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|
|
|
|
|
|
|
Primary source |
RefSeq : NM_001127703.1 (GI:189163533)
|
Name |
Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (SERPINA1), transcript variant 7
|
Type of transcript |
mRNA
|
Organism |
Homo sapiens
|
Length |
3495 nt
|
Map |
14q32.1
|
Location |
Chromosome 14 (NC_000014.8) strand : -
94843083...94844976 | 94845800...94845947 | 94847207...94847477 | 94848928...94849577 |
94854896...94854999 | 94855155...94855346 | 94856793...94857028 |
|
|
|
|
|
|
|
|
|
|
|
|
|
Exon(s) |
Start |
End |
Length |
is coding |
Exon 1a
|
1
|
236
|
236
|
1
|
Exon 2a
|
237
|
428
|
192
|
1
|
Exon 2d
|
429
|
532
|
104
|
1
|
Exon 3
|
533
|
1182
|
650
|
1
|
Exon 4
|
1183
|
1453
|
271
|
1
|
Exon 5
|
1454
|
1601
|
148
|
1
|
Exon 6
|
1602
|
3495
|
1894
|
1
|
|
|
|
|
|
|
|
|
|
|
|
|
ID |
Class |
Location |
Mutation |
Length |
is synonymous |
Source |
|
|
|
|
|
|
|
|
|
|
|
|
Primary source |
NCBI : CCDS9925
|
Nucleotide |
SERPINA1, mRNA isoform 7[NM_001127703.1] : 537...1793
|
Length |
1257
|
Location |
Chromosome 14 (NC_000014.8) strand : -
94844785...94844976 | 94845800...94845947 | 94847207...94847477 | 94848928...94849573 |
|
Start codon |
1
|
Translation |
NP_001121175.1 |
|
|
|
|
|
|
|
|
|
|
|
|
1 |
TGGGCAGGAA |
CTGGGCACTG |
TGCCCAGGGC |
ATGCACTGCC |
TCCACGCAGC |
AACCCTCAGA |
GTCCTGAGCT |
GAACCAAGAA |
|
81 |
GGAGGAGGGG |
GTCGGGCCTC |
CGAGGAAGGC |
CTAGCCGCTG |
CTGCTGCCAG |
GAATTCCAGG |
TTGGAGGGGC |
GGCAACCTCC |
|
161 |
TGCCAGCCTT |
CAGGCCACTC |
TCCTGTGCCT |
GCCAGAAGAG |
ACAGAGCTTG |
AGGAGAGCTT |
GAGGAGAGCA |
GGAAAGGGCG |
|
241 |
GCAGTAAGTC |
TTCAGCATCA |
GGCATTTTGG |
GGTGACTCAG |
TAAATGGTAG |
ATCTTGCTAC |
CAGTGGAACA |
GCCACTAAGG |
|
321 |
ATTCTGCAGT |
GAGAGCAGAG |
GGCCAGCTAA |
GTGGTACTCT |
CCCAGAGACT |
GTCTGACTCA |
CGCCACCCCC |
TCCACCTTGG |
|
401 |
ACACAGGACG |
CTGTGGTTTC |
TGAGCCAGCA |
GCCTCCCCCG |
TTGCCCCTCT |
GGATCCACTG |
CTTAAATACG |
GACGAGGACA |
|
481 |
GGGCCCTGTC |
TCCTCAGCTT |
CAGGCACCAC |
CACTGACCTG |
GGACAGTGAA |
TCGACAATGC |
CGTCTTCTGT |
CTCGTGGGGC |
|
561 |
ATCCTCCTGC |
TGGCAGGCCT |
GTGCTGCCTG |
GTCCCTGTCT |
CCCTGGCTGA |
GGATCCCCAG |
GGAGATGCTG |
CCCAGAAGAC |
|
641 |
AGATACATCC |
CACCATGATC |
AGGATCACCC |
AACCTTCAAC |
AAGATCACCC |
CCAACCTGGC |
TGAGTTCGCC |
TTCAGCCTAT |
|
721 |
ACCGCCAGCT |
GGCACACCAG |
TCCAACAGCA |
CCAATATCTT |
CTTCTCCCCA |
GTGAGCATCG |
CTACAGCCTT |
TGCAATGCTC |
|
801 |
TCCCTGGGGA |
CCAAGGCTGA |
CACTCACGAT |
GAAATCCTGG |
AGGGCCTGAA |
TTTCAACCTC |
ACGGAGATTC |
CGGAGGCTCA |
|
881 |
GATCCATGAA |
GGCTTCCAGG |
AACTCCTCCG |
TACCCTCAAC |
CAGCCAGACA |
GCCAGCTCCA |
GCTGACCACC |
GGCAATGGCC |
|
961 |
TGTTCCTCAG |
CGAGGGCCTG |
AAGCTAGTGG |
ATAAGTTTTT |
GGAGGATGTT |
AAAAAGTTGT |
ACCACTCAGA |
AGCCTTCACT |
|
1041 |
GTCAACTTCG |
GGGACACCGA |
AGAGGCCAAG |
AAACAGATCA |
ACGATTACGT |
GGAGAAGGGT |
ACTCAAGGGA |
AAATTGTGGA |
|
1121 |
TTTGGTCAAG |
GAGCTTGACA |
GAGACACAGT |
TTTTGCTCTG |
GTGAATTACA |
TCTTCTTTAA |
AGGCAAATGG |
GAGAGACCCT |
|
1201 |
TTGAAGTCAA |
GGACACCGAG |
GAAGAGGACT |
TCCACGTGGA |
CCAGGTGACC |
ACCGTGAAGG |
TGCCTATGAT |
GAAGCGTTTA |
|
1281 |
GGCATGTTTA |
ACATCCAGCA |
CTGTAAGAAG |
CTGTCCAGCT |
GGGTGCTGCT |
GATGAAATAC |
CTGGGCAATG |
CCACCGCCAT |
|
1361 |
CTTCTTCCTG |
CCTGATGAGG |
GGAAACTACA |
GCACCTGGAA |
AATGAACTCA |
CCCACGATAT |
CATCACCAAG |
TTCCTGGAAA |
|
1441 |
ATGAAGACAG |
AAGGTCTGCC |
AGCTTACATT |
TACCCAAACT |
GTCCATTACT |
GGAACCTATG |
ATCTGAAGAG |
CGTCCTGGGT |
|
1521 |
CAACTGGGCA |
TCACTAAGGT |
CTTCAGCAAT |
GGGGCTGACC |
TCTCCGGGGT |
CACAGAGGAG |
GCACCCCTGA |
AGCTCTCCAA |
|
1601 |
GGCCGTGCAT |
AAGGCTGTGC |
TGACCATCGA |
CGAGAAAGGG |
ACTGAAGCTG |
CTGGGGCCAT |
GTTTTTAGAG |
GCCATACCCA |
|
1681 |
TGTCTATCCC |
CCCCGAGGTC |
AAGTTCAACA |
AACCCTTTGT |
CTTCTTAATG |
ATTGAACAAA |
ATACCAAGTC |
TCCCCTCTTC |
|
1761 |
ATGGGAAAAG |
TGGTGAATCC |
CACCCAAAAA |
TAACTGCCTC |
TCGCTCCTCA |
ACCCCTCCCC |
TCCATCCCTG |
GCCCCCTCCC |
|
1841 |
TGGATGACAT |
TAAAGAAGGG |
TTGAGCTGGT |
CCCTGCCTGC |
ATGTGACTGT |
AAATCCCTCC |
CATGTTTTCT |
CTGAGTCTCC |
|
1921 |
CTTTGCCTGC |
TGAGGCTGTA |
TGTGGGCTCC |
AGGTAACAGT |
GCTGTCTTCG |
GGCCCCCTGA |
ACTGTGTTCA |
TGGAGCATCT |
|
2001 |
GGCTGGGTAG |
GCACATGCTG |
GGCTTGAATC |
CAGGGGGGAC |
TGAATCCTCA |
GCTTACGGAC |
CTGGGCCCAT |
CTGTTTCTGG |
|
2081 |
AGGGCTCCAG |
TCTTCCTTGT |
CCTGTCTTGG |
AGTCCCCAAG |
AAGGAATCAC |
AGGGGAGGAA |
CCAGATACCA |
GCCATGACCC |
|
2161 |
CAGGCTCCAC |
CAAGCATCTT |
CATGTCCCCC |
TGCTCATCCC |
CCACTCCCCC |
CCACCCAGAG |
TTGCTCATCC |
TGCCAGGGCT |
|
2241 |
GGCTGTGCCC |
ACCCCAAGGC |
TGCCCTCCTG |
GGGGCCCCAG |
AACTGCCTGA |
TCGTGCCGTG |
GCCCAGTTTT |
GTGGCATCTG |
|
2321 |
CAGCAACACA |
AGAGAGAGGA |
CAATGTCCTC |
CTCTTGACCC |
GCTGTCACCT |
AACCAGACTC |
GGGCCCTGCA |
CCTCTCAGGC |
|
2401 |
ACTTCTGGAA |
AATGACTGAG |
GCAGATTCTT |
CCTGAAGCCC |
ATTCTCCATG |
GGGCAACAAG |
GACACCTATT |
CTGTCCTTGT |
|
2481 |
CCTTCCATCG |
CTGCCCCAGA |
AAGCCTCACA |
TATCTCCGTT |
TAGAATCAGG |
TCCCTTCTCC |
CCAGATGAAG |
AGGAGGGTCT |
|
2561 |
CTGCTTTGTT |
TTCTCTATCT |
CCTCCTCAGA |
CTTGACCAGG |
CCCAGCAGGC |
CCCAGAAGAC |
CATTACCCTA |
TATCCCTTCT |
|
2641 |
CCTCCCTAGT |
CACATGGCCA |
TAGGCCTGCT |
GATGGCTCAG |
GAAGGCCATT |
GCAAGGACTC |
CTCAGCTATG |
GGAGAGGAAG |
|
2721 |
CACATCACCC |
ATTGACCCCC |
GCAACCCCTC |
CCTTTCCTCC |
TCTGAGTCCC |
GACTGGGGCC |
ACATGCAGCC |
TGACTTCTTT |
|
2801 |
GTGCCTGTTG |
CTGTCCCTGC |
AGTCTTCAGA |
GGGCCACCGC |
AGCTCCAGTG |
CCACGGCAGG |
AGGCTGTTCC |
TGAATAGCCC |
|
2881 |
CTGTGGTAAG |
GGCCAGGAGA |
GTCCTTCCAT |
CCTCCAAGGC |
CCTGCTAAAG |
GACACAGCAG |
CCAGGAAGTC |
CCCTGGGCCC |
|
2961 |
CTAGCTGAAG |
GACAGCCTGC |
TCCCTCCGTC |
TCTACCAGGA |
ATGGCCTTGT |
CCTATGGAAG |
GCACTGCCCC |
ATCCCAAACT |
|
3041 |
AATCTAGGAA |
TCACTGTCTA |
ACCACTCACT |
GTCATGAATG |
TGTACTTAAA |
GGATGAGGTT |
GAGTCATACC |
AAATAGTGAT |
|
3121 |
TTCGATAGTT |
CAAAATGGTG |
AAATTAGCAA |
TTCTACATGA |
TTCAGTCTAA |
TCAATGGATA |
CCGACTGTTT |
CCCACACAAG |
|
3201 |
TCTCCTGTTC |
TCTTAAGCTT |
ACTCACTGAC |
AGCCTTTCAC |
TCTCCACAAA |
TACATTAAAG |
ATATGGCCAT |
CACCAAGCCC |
|
3281 |
CCTAGGATGA |
CACCAGACCT |
GAGAGTCTGA |
AGACCTGGAT |
CCAAGTTCTG |
ACTTTTCCCC |
CTGACAGCTG |
TGTGACCTTC |
|
3361 |
GTGAAGTCGC |
CAAACCTCTC |
TGAGCCCCAG |
TCATTGCTAG |
TAAGACCTGC |
CTTTGAGTTG |
GTATGATGTT |
CAAGTTAGAT |
|
3441 |
AACAAAATGT |
TTATACCCAT |
TAGAACAGAG |
AATAAATAGA |
ACTACATTTC |
TTGCA |
|
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|
>gi|189163533|ref|NM_001127703.1|Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (SERPINA1), transcript variant 7
TGGGCAGGAACTGGGCACTGTGCCCAGGGCATGCACTGCCTCCACGCAGCAACCCTCAGAGTCCTGAGCTGAACCAAGAA
GGAGGAGGGGGTCGGGCCTCCGAGGAAGGCCTAGCCGCTGCTGCTGCCAGGAATTCCAGGTTGGAGGGGCGGCAACCTCC
TGCCAGCCTTCAGGCCACTCTCCTGTGCCTGCCAGAAGAGACAGAGCTTGAGGAGAGCTTGAGGAGAGCAGGAAAGGGCG
GCAGTAAGTCTTCAGCATCAGGCATTTTGGGGTGACTCAGTAAATGGTAGATCTTGCTACCAGTGGAACAGCCACTAAGG
ATTCTGCAGTGAGAGCAGAGGGCCAGCTAAGTGGTACTCTCCCAGAGACTGTCTGACTCACGCCACCCCCTCCACCTTGG
ACACAGGACGCTGTGGTTTCTGAGCCAGCAGCCTCCCCCGTTGCCCCTCTGGATCCACTGCTTAAATACGGACGAGGACA
GGGCCCTGTCTCCTCAGCTTCAGGCACCACCACTGACCTGGGACAGTGAATCGACAATGCCGTCTTCTGTCTCGTGGGGC
ATCCTCCTGCTGGCAGGCCTGTGCTGCCTGGTCCCTGTCTCCCTGGCTGAGGATCCCCAGGGAGATGCTGCCCAGAAGAC
AGATACATCCCACCATGATCAGGATCACCCAACCTTCAACAAGATCACCCCCAACCTGGCTGAGTTCGCCTTCAGCCTAT
ACCGCCAGCTGGCACACCAGTCCAACAGCACCAATATCTTCTTCTCCCCAGTGAGCATCGCTACAGCCTTTGCAATGCTC
TCCCTGGGGACCAAGGCTGACACTCACGATGAAATCCTGGAGGGCCTGAATTTCAACCTCACGGAGATTCCGGAGGCTCA
GATCCATGAAGGCTTCCAGGAACTCCTCCGTACCCTCAACCAGCCAGACAGCCAGCTCCAGCTGACCACCGGCAATGGCC
TGTTCCTCAGCGAGGGCCTGAAGCTAGTGGATAAGTTTTTGGAGGATGTTAAAAAGTTGTACCACTCAGAAGCCTTCACT
GTCAACTTCGGGGACACCGAAGAGGCCAAGAAACAGATCAACGATTACGTGGAGAAGGGTACTCAAGGGAAAATTGTGGA
TTTGGTCAAGGAGCTTGACAGAGACACAGTTTTTGCTCTGGTGAATTACATCTTCTTTAAAGGCAAATGGGAGAGACCCT
TTGAAGTCAAGGACACCGAGGAAGAGGACTTCCACGTGGACCAGGTGACCACCGTGAAGGTGCCTATGATGAAGCGTTTA
GGCATGTTTAACATCCAGCACTGTAAGAAGCTGTCCAGCTGGGTGCTGCTGATGAAATACCTGGGCAATGCCACCGCCAT
CTTCTTCCTGCCTGATGAGGGGAAACTACAGCACCTGGAAAATGAACTCACCCACGATATCATCACCAAGTTCCTGGAAA
ATGAAGACAGAAGGTCTGCCAGCTTACATTTACCCAAACTGTCCATTACTGGAACCTATGATCTGAAGAGCGTCCTGGGT
CAACTGGGCATCACTAAGGTCTTCAGCAATGGGGCTGACCTCTCCGGGGTCACAGAGGAGGCACCCCTGAAGCTCTCCAA
GGCCGTGCATAAGGCTGTGCTGACCATCGACGAGAAAGGGACTGAAGCTGCTGGGGCCATGTTTTTAGAGGCCATACCCA
TGTCTATCCCCCCCGAGGTCAAGTTCAACAAACCCTTTGTCTTCTTAATGATTGAACAAAATACCAAGTCTCCCCTCTTC
ATGGGAAAAGTGGTGAATCCCACCCAAAAATAACTGCCTCTCGCTCCTCAACCCCTCCCCTCCATCCCTGGCCCCCTCCC
TGGATGACATTAAAGAAGGGTTGAGCTGGTCCCTGCCTGCATGTGACTGTAAATCCCTCCCATGTTTTCTCTGAGTCTCC
CTTTGCCTGCTGAGGCTGTATGTGGGCTCCAGGTAACAGTGCTGTCTTCGGGCCCCCTGAACTGTGTTCATGGAGCATCT
GGCTGGGTAGGCACATGCTGGGCTTGAATCCAGGGGGGACTGAATCCTCAGCTTACGGACCTGGGCCCATCTGTTTCTGG
AGGGCTCCAGTCTTCCTTGTCCTGTCTTGGAGTCCCCAAGAAGGAATCACAGGGGAGGAACCAGATACCAGCCATGACCC
CAGGCTCCACCAAGCATCTTCATGTCCCCCTGCTCATCCCCCACTCCCCCCCACCCAGAGTTGCTCATCCTGCCAGGGCT
GGCTGTGCCCACCCCAAGGCTGCCCTCCTGGGGGCCCCAGAACTGCCTGATCGTGCCGTGGCCCAGTTTTGTGGCATCTG
CAGCAACACAAGAGAGAGGACAATGTCCTCCTCTTGACCCGCTGTCACCTAACCAGACTCGGGCCCTGCACCTCTCAGGC
ACTTCTGGAAAATGACTGAGGCAGATTCTTCCTGAAGCCCATTCTCCATGGGGCAACAAGGACACCTATTCTGTCCTTGT
CCTTCCATCGCTGCCCCAGAAAGCCTCACATATCTCCGTTTAGAATCAGGTCCCTTCTCCCCAGATGAAGAGGAGGGTCT
CTGCTTTGTTTTCTCTATCTCCTCCTCAGACTTGACCAGGCCCAGCAGGCCCCAGAAGACCATTACCCTATATCCCTTCT
CCTCCCTAGTCACATGGCCATAGGCCTGCTGATGGCTCAGGAAGGCCATTGCAAGGACTCCTCAGCTATGGGAGAGGAAG
CACATCACCCATTGACCCCCGCAACCCCTCCCTTTCCTCCTCTGAGTCCCGACTGGGGCCACATGCAGCCTGACTTCTTT
GTGCCTGTTGCTGTCCCTGCAGTCTTCAGAGGGCCACCGCAGCTCCAGTGCCACGGCAGGAGGCTGTTCCTGAATAGCCC
CTGTGGTAAGGGCCAGGAGAGTCCTTCCATCCTCCAAGGCCCTGCTAAAGGACACAGCAGCCAGGAAGTCCCCTGGGCCC
CTAGCTGAAGGACAGCCTGCTCCCTCCGTCTCTACCAGGAATGGCCTTGTCCTATGGAAGGCACTGCCCCATCCCAAACT
AATCTAGGAATCACTGTCTAACCACTCACTGTCATGAATGTGTACTTAAAGGATGAGGTTGAGTCATACCAAATAGTGAT
TTCGATAGTTCAAAATGGTGAAATTAGCAATTCTACATGATTCAGTCTAATCAATGGATACCGACTGTTTCCCACACAAG
TCTCCTGTTCTCTTAAGCTTACTCACTGACAGCCTTTCACTCTCCACAAATACATTAAAGATATGGCCATCACCAAGCCC
CCTAGGATGACACCAGACCTGAGAGTCTGAAGACCTGGATCCAAGTTCTGACTTTTCCCCCTGACAGCTGTGTGACCTTC
GTGAAGTCGCCAAACCTCTCTGAGCCCCAGTCATTGCTAGTAAGACCTGCCTTTGAGTTGGTATGATGTTCAAGTTAGAT
AACAAAATGTTTATACCCATTAGAACAGAGAATAAATAGAACTACATTTCTTGCA
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Primary source |
RefSeq : NM_001127704.1 (GI:189163535)
|
Name |
Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (SERPINA1), transcript variant 8
|
Type of transcript |
mRNA
|
Organism |
Homo sapiens
|
Length |
3492 nt
|
Map |
14q32.1
|
Location |
Chromosome 14 (NC_000014.8) strand : -
94843083...94844976 | 94845800...94845947 | 94847207...94847477 | 94848928...94849577 |
94854896...94854996 | 94855155...94855346 | 94856793...94857028 |
|
|
|
|
|
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|
|
|
|
|
|
|
Exon(s) |
Start |
End |
Length |
is coding |
Exon 1a
|
1
|
236
|
236
|
1
|
Exon 2a
|
237
|
428
|
192
|
1
|
Exon 2e
|
429
|
529
|
101
|
1
|
Exon 3
|
530
|
1179
|
650
|
1
|
Exon 4
|
1180
|
1450
|
271
|
1
|
Exon 5
|
1451
|
1598
|
148
|
1
|
Exon 6
|
1599
|
3492
|
1894
|
1
|
|
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ID |
Class |
Location |
Mutation |
Length |
is synonymous |
Source |
rs2070609
|
SNP
|
373
|
c/g
|
1
|
?
|
dbSNP
|
|
|
|
|
|
|
|
|
|
|
|
|
Primary source |
NCBI : CCDS9925
|
Nucleotide |
SERPINA1, mRNA isoform 8[NM_001127704.1] : 534...1790
|
Length |
1257
|
Location |
Chromosome 14 (NC_000014.8) strand : -
94844785...94844976 | 94845800...94845947 | 94847207...94847477 | 94848928...94849573 |
|
Start codon |
1
|
Translation |
NP_001121176.1 |
|
|
|
|
|
|
|
|
|
|
|
|
1 |
TGGGCAGGAA |
CTGGGCACTG |
TGCCCAGGGC |
ATGCACTGCC |
TCCACGCAGC |
AACCCTCAGA |
GTCCTGAGCT |
GAACCAAGAA |
|
81 |
GGAGGAGGGG |
GTCGGGCCTC |
CGAGGAAGGC |
CTAGCCGCTG |
CTGCTGCCAG |
GAATTCCAGG |
TTGGAGGGGC |
GGCAACCTCC |
|
161 |
TGCCAGCCTT |
CAGGCCACTC |
TCCTGTGCCT |
GCCAGAAGAG |
ACAGAGCTTG |
AGGAGAGCTT |
GAGGAGAGCA |
GGAAAGGGCG |
|
241 |
GCAGTAAGTC |
TTCAGCATCA |
GGCATTTTGG |
GGTGACTCAG |
TAAATGGTAG |
ATCTTGCTAC |
CAGTGGAACA |
GCCACTAAGG |
|
321 |
ATTCTGCAGT |
GAGAGCAGAG |
GGCCAGCTAA |
GTGGTACTCT |
CCCAGAGACT |
GTCTGACTCA |
CGCCACCCCC |
TCCACCTTGG |
|
401 |
ACACAGGACG |
CTGTGGTTTC |
TGAGCCAGCC |
TCCCCCGTTG |
CCCCTCTGGA |
TCCACTGCTT |
AAATACGGAC |
GAGGACAGGG |
|
481 |
CCCTGTCTCC |
TCAGCTTCAG |
GCACCACCAC |
TGACCTGGGA |
CAGTGAATCG |
ACAATGCCGT |
CTTCTGTCTC |
GTGGGGCATC |
|
561 |
CTCCTGCTGG |
CAGGCCTGTG |
CTGCCTGGTC |
CCTGTCTCCC |
TGGCTGAGGA |
TCCCCAGGGA |
GATGCTGCCC |
AGAAGACAGA |
|
641 |
TACATCCCAC |
CATGATCAGG |
ATCACCCAAC |
CTTCAACAAG |
ATCACCCCCA |
ACCTGGCTGA |
GTTCGCCTTC |
AGCCTATACC |
|
721 |
GCCAGCTGGC |
ACACCAGTCC |
AACAGCACCA |
ATATCTTCTT |
CTCCCCAGTG |
AGCATCGCTA |
CAGCCTTTGC |
AATGCTCTCC |
|
801 |
CTGGGGACCA |
AGGCTGACAC |
TCACGATGAA |
ATCCTGGAGG |
GCCTGAATTT |
CAACCTCACG |
GAGATTCCGG |
AGGCTCAGAT |
|
881 |
CCATGAAGGC |
TTCCAGGAAC |
TCCTCCGTAC |
CCTCAACCAG |
CCAGACAGCC |
AGCTCCAGCT |
GACCACCGGC |
AATGGCCTGT |
|
961 |
TCCTCAGCGA |
GGGCCTGAAG |
CTAGTGGATA |
AGTTTTTGGA |
GGATGTTAAA |
AAGTTGTACC |
ACTCAGAAGC |
CTTCACTGTC |
|
1041 |
AACTTCGGGG |
ACACCGAAGA |
GGCCAAGAAA |
CAGATCAACG |
ATTACGTGGA |
GAAGGGTACT |
CAAGGGAAAA |
TTGTGGATTT |
|
1121 |
GGTCAAGGAG |
CTTGACAGAG |
ACACAGTTTT |
TGCTCTGGTG |
AATTACATCT |
TCTTTAAAGG |
CAAATGGGAG |
AGACCCTTTG |
|
1201 |
AAGTCAAGGA |
CACCGAGGAA |
GAGGACTTCC |
ACGTGGACCA |
GGTGACCACC |
GTGAAGGTGC |
CTATGATGAA |
GCGTTTAGGC |
|
1281 |
ATGTTTAACA |
TCCAGCACTG |
TAAGAAGCTG |
TCCAGCTGGG |
TGCTGCTGAT |
GAAATACCTG |
GGCAATGCCA |
CCGCCATCTT |
|
1361 |
CTTCCTGCCT |
GATGAGGGGA |
AACTACAGCA |
CCTGGAAAAT |
GAACTCACCC |
ACGATATCAT |
CACCAAGTTC |
CTGGAAAATG |
|
1441 |
AAGACAGAAG |
GTCTGCCAGC |
TTACATTTAC |
CCAAACTGTC |
CATTACTGGA |
ACCTATGATC |
TGAAGAGCGT |
CCTGGGTCAA |
|
1521 |
CTGGGCATCA |
CTAAGGTCTT |
CAGCAATGGG |
GCTGACCTCT |
CCGGGGTCAC |
AGAGGAGGCA |
CCCCTGAAGC |
TCTCCAAGGC |
|
1601 |
CGTGCATAAG |
GCTGTGCTGA |
CCATCGACGA |
GAAAGGGACT |
GAAGCTGCTG |
GGGCCATGTT |
TTTAGAGGCC |
ATACCCATGT |
|
1681 |
CTATCCCCCC |
CGAGGTCAAG |
TTCAACAAAC |
CCTTTGTCTT |
CTTAATGATT |
GAACAAAATA |
CCAAGTCTCC |
CCTCTTCATG |
|
1761 |
GGAAAAGTGG |
TGAATCCCAC |
CCAAAAATAA |
CTGCCTCTCG |
CTCCTCAACC |
CCTCCCCTCC |
ATCCCTGGCC |
CCCTCCCTGG |
|
1841 |
ATGACATTAA |
AGAAGGGTTG |
AGCTGGTCCC |
TGCCTGCATG |
TGACTGTAAA |
TCCCTCCCAT |
GTTTTCTCTG |
AGTCTCCCTT |
|
1921 |
TGCCTGCTGA |
GGCTGTATGT |
GGGCTCCAGG |
TAACAGTGCT |
GTCTTCGGGC |
CCCCTGAACT |
GTGTTCATGG |
AGCATCTGGC |
|
2001 |
TGGGTAGGCA |
CATGCTGGGC |
TTGAATCCAG |
GGGGGACTGA |
ATCCTCAGCT |
TACGGACCTG |
GGCCCATCTG |
TTTCTGGAGG |
|
2081 |
GCTCCAGTCT |
TCCTTGTCCT |
GTCTTGGAGT |
CCCCAAGAAG |
GAATCACAGG |
GGAGGAACCA |
GATACCAGCC |
ATGACCCCAG |
|
2161 |
GCTCCACCAA |
GCATCTTCAT |
GTCCCCCTGC |
TCATCCCCCA |
CTCCCCCCCA |
CCCAGAGTTG |
CTCATCCTGC |
CAGGGCTGGC |
|
2241 |
TGTGCCCACC |
CCAAGGCTGC |
CCTCCTGGGG |
GCCCCAGAAC |
TGCCTGATCG |
TGCCGTGGCC |
CAGTTTTGTG |
GCATCTGCAG |
|
2321 |
CAACACAAGA |
GAGAGGACAA |
TGTCCTCCTC |
TTGACCCGCT |
GTCACCTAAC |
CAGACTCGGG |
CCCTGCACCT |
CTCAGGCACT |
|
2401 |
TCTGGAAAAT |
GACTGAGGCA |
GATTCTTCCT |
GAAGCCCATT |
CTCCATGGGG |
CAACAAGGAC |
ACCTATTCTG |
TCCTTGTCCT |
|
2481 |
TCCATCGCTG |
CCCCAGAAAG |
CCTCACATAT |
CTCCGTTTAG |
AATCAGGTCC |
CTTCTCCCCA |
GATGAAGAGG |
AGGGTCTCTG |
|
2561 |
CTTTGTTTTC |
TCTATCTCCT |
CCTCAGACTT |
GACCAGGCCC |
AGCAGGCCCC |
AGAAGACCAT |
TACCCTATAT |
CCCTTCTCCT |
|
2641 |
CCCTAGTCAC |
ATGGCCATAG |
GCCTGCTGAT |
GGCTCAGGAA |
GGCCATTGCA |
AGGACTCCTC |
AGCTATGGGA |
GAGGAAGCAC |
|
2721 |
ATCACCCATT |
GACCCCCGCA |
ACCCCTCCCT |
TTCCTCCTCT |
GAGTCCCGAC |
TGGGGCCACA |
TGCAGCCTGA |
CTTCTTTGTG |
|
2801 |
CCTGTTGCTG |
TCCCTGCAGT |
CTTCAGAGGG |
CCACCGCAGC |
TCCAGTGCCA |
CGGCAGGAGG |
CTGTTCCTGA |
ATAGCCCCTG |
|
2881 |
TGGTAAGGGC |
CAGGAGAGTC |
CTTCCATCCT |
CCAAGGCCCT |
GCTAAAGGAC |
ACAGCAGCCA |
GGAAGTCCCC |
TGGGCCCCTA |
|
2961 |
GCTGAAGGAC |
AGCCTGCTCC |
CTCCGTCTCT |
ACCAGGAATG |
GCCTTGTCCT |
ATGGAAGGCA |
CTGCCCCATC |
CCAAACTAAT |
|
3041 |
CTAGGAATCA |
CTGTCTAACC |
ACTCACTGTC |
ATGAATGTGT |
ACTTAAAGGA |
TGAGGTTGAG |
TCATACCAAA |
TAGTGATTTC |
|
3121 |
GATAGTTCAA |
AATGGTGAAA |
TTAGCAATTC |
TACATGATTC |
AGTCTAATCA |
ATGGATACCG |
ACTGTTTCCC |
ACACAAGTCT |
|
3201 |
CCTGTTCTCT |
TAAGCTTACT |
CACTGACAGC |
CTTTCACTCT |
CCACAAATAC |
ATTAAAGATA |
TGGCCATCAC |
CAAGCCCCCT |
|
3281 |
AGGATGACAC |
CAGACCTGAG |
AGTCTGAAGA |
CCTGGATCCA |
AGTTCTGACT |
TTTCCCCCTG |
ACAGCTGTGT |
GACCTTCGTG |
|
3361 |
AAGTCGCCAA |
ACCTCTCTGA |
GCCCCAGTCA |
TTGCTAGTAA |
GACCTGCCTT |
TGAGTTGGTA |
TGATGTTCAA |
GTTAGATAAC |
|
3441 |
AAAATGTTTA |
TACCCATTAG |
AACAGAGAAT |
AAATAGAACT |
ACATTTCTTG |
CA |
|
|
|
|
|
|
|
|
|
|
|
|
>gi|189163535|ref|NM_001127704.1|Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (SERPINA1), transcript variant 8
TGGGCAGGAACTGGGCACTGTGCCCAGGGCATGCACTGCCTCCACGCAGCAACCCTCAGAGTCCTGAGCTGAACCAAGAA
GGAGGAGGGGGTCGGGCCTCCGAGGAAGGCCTAGCCGCTGCTGCTGCCAGGAATTCCAGGTTGGAGGGGCGGCAACCTCC
TGCCAGCCTTCAGGCCACTCTCCTGTGCCTGCCAGAAGAGACAGAGCTTGAGGAGAGCTTGAGGAGAGCAGGAAAGGGCG
GCAGTAAGTCTTCAGCATCAGGCATTTTGGGGTGACTCAGTAAATGGTAGATCTTGCTACCAGTGGAACAGCCACTAAGG
ATTCTGCAGTGAGAGCAGAGGGCCAGCTAAGTGGTACTCTCCCAGAGACTGTCTGACTCACGCCACCCCCTCCACCTTGG
ACACAGGACGCTGTGGTTTCTGAGCCAGCCTCCCCCGTTGCCCCTCTGGATCCACTGCTTAAATACGGACGAGGACAGGG
CCCTGTCTCCTCAGCTTCAGGCACCACCACTGACCTGGGACAGTGAATCGACAATGCCGTCTTCTGTCTCGTGGGGCATC
CTCCTGCTGGCAGGCCTGTGCTGCCTGGTCCCTGTCTCCCTGGCTGAGGATCCCCAGGGAGATGCTGCCCAGAAGACAGA
TACATCCCACCATGATCAGGATCACCCAACCTTCAACAAGATCACCCCCAACCTGGCTGAGTTCGCCTTCAGCCTATACC
GCCAGCTGGCACACCAGTCCAACAGCACCAATATCTTCTTCTCCCCAGTGAGCATCGCTACAGCCTTTGCAATGCTCTCC
CTGGGGACCAAGGCTGACACTCACGATGAAATCCTGGAGGGCCTGAATTTCAACCTCACGGAGATTCCGGAGGCTCAGAT
CCATGAAGGCTTCCAGGAACTCCTCCGTACCCTCAACCAGCCAGACAGCCAGCTCCAGCTGACCACCGGCAATGGCCTGT
TCCTCAGCGAGGGCCTGAAGCTAGTGGATAAGTTTTTGGAGGATGTTAAAAAGTTGTACCACTCAGAAGCCTTCACTGTC
AACTTCGGGGACACCGAAGAGGCCAAGAAACAGATCAACGATTACGTGGAGAAGGGTACTCAAGGGAAAATTGTGGATTT
GGTCAAGGAGCTTGACAGAGACACAGTTTTTGCTCTGGTGAATTACATCTTCTTTAAAGGCAAATGGGAGAGACCCTTTG
AAGTCAAGGACACCGAGGAAGAGGACTTCCACGTGGACCAGGTGACCACCGTGAAGGTGCCTATGATGAAGCGTTTAGGC
ATGTTTAACATCCAGCACTGTAAGAAGCTGTCCAGCTGGGTGCTGCTGATGAAATACCTGGGCAATGCCACCGCCATCTT
CTTCCTGCCTGATGAGGGGAAACTACAGCACCTGGAAAATGAACTCACCCACGATATCATCACCAAGTTCCTGGAAAATG
AAGACAGAAGGTCTGCCAGCTTACATTTACCCAAACTGTCCATTACTGGAACCTATGATCTGAAGAGCGTCCTGGGTCAA
CTGGGCATCACTAAGGTCTTCAGCAATGGGGCTGACCTCTCCGGGGTCACAGAGGAGGCACCCCTGAAGCTCTCCAAGGC
CGTGCATAAGGCTGTGCTGACCATCGACGAGAAAGGGACTGAAGCTGCTGGGGCCATGTTTTTAGAGGCCATACCCATGT
CTATCCCCCCCGAGGTCAAGTTCAACAAACCCTTTGTCTTCTTAATGATTGAACAAAATACCAAGTCTCCCCTCTTCATG
GGAAAAGTGGTGAATCCCACCCAAAAATAACTGCCTCTCGCTCCTCAACCCCTCCCCTCCATCCCTGGCCCCCTCCCTGG
ATGACATTAAAGAAGGGTTGAGCTGGTCCCTGCCTGCATGTGACTGTAAATCCCTCCCATGTTTTCTCTGAGTCTCCCTT
TGCCTGCTGAGGCTGTATGTGGGCTCCAGGTAACAGTGCTGTCTTCGGGCCCCCTGAACTGTGTTCATGGAGCATCTGGC
TGGGTAGGCACATGCTGGGCTTGAATCCAGGGGGGACTGAATCCTCAGCTTACGGACCTGGGCCCATCTGTTTCTGGAGG
GCTCCAGTCTTCCTTGTCCTGTCTTGGAGTCCCCAAGAAGGAATCACAGGGGAGGAACCAGATACCAGCCATGACCCCAG
GCTCCACCAAGCATCTTCATGTCCCCCTGCTCATCCCCCACTCCCCCCCACCCAGAGTTGCTCATCCTGCCAGGGCTGGC
TGTGCCCACCCCAAGGCTGCCCTCCTGGGGGCCCCAGAACTGCCTGATCGTGCCGTGGCCCAGTTTTGTGGCATCTGCAG
CAACACAAGAGAGAGGACAATGTCCTCCTCTTGACCCGCTGTCACCTAACCAGACTCGGGCCCTGCACCTCTCAGGCACT
TCTGGAAAATGACTGAGGCAGATTCTTCCTGAAGCCCATTCTCCATGGGGCAACAAGGACACCTATTCTGTCCTTGTCCT
TCCATCGCTGCCCCAGAAAGCCTCACATATCTCCGTTTAGAATCAGGTCCCTTCTCCCCAGATGAAGAGGAGGGTCTCTG
CTTTGTTTTCTCTATCTCCTCCTCAGACTTGACCAGGCCCAGCAGGCCCCAGAAGACCATTACCCTATATCCCTTCTCCT
CCCTAGTCACATGGCCATAGGCCTGCTGATGGCTCAGGAAGGCCATTGCAAGGACTCCTCAGCTATGGGAGAGGAAGCAC
ATCACCCATTGACCCCCGCAACCCCTCCCTTTCCTCCTCTGAGTCCCGACTGGGGCCACATGCAGCCTGACTTCTTTGTG
CCTGTTGCTGTCCCTGCAGTCTTCAGAGGGCCACCGCAGCTCCAGTGCCACGGCAGGAGGCTGTTCCTGAATAGCCCCTG
TGGTAAGGGCCAGGAGAGTCCTTCCATCCTCCAAGGCCCTGCTAAAGGACACAGCAGCCAGGAAGTCCCCTGGGCCCCTA
GCTGAAGGACAGCCTGCTCCCTCCGTCTCTACCAGGAATGGCCTTGTCCTATGGAAGGCACTGCCCCATCCCAAACTAAT
CTAGGAATCACTGTCTAACCACTCACTGTCATGAATGTGTACTTAAAGGATGAGGTTGAGTCATACCAAATAGTGATTTC
GATAGTTCAAAATGGTGAAATTAGCAATTCTACATGATTCAGTCTAATCAATGGATACCGACTGTTTCCCACACAAGTCT
CCTGTTCTCTTAAGCTTACTCACTGACAGCCTTTCACTCTCCACAAATACATTAAAGATATGGCCATCACCAAGCCCCCT
AGGATGACACCAGACCTGAGAGTCTGAAGACCTGGATCCAAGTTCTGACTTTTCCCCCTGACAGCTGTGTGACCTTCGTG
AAGTCGCCAAACCTCTCTGAGCCCCAGTCATTGCTAGTAAGACCTGCCTTTGAGTTGGTATGATGTTCAAGTTAGATAAC
AAAATGTTTATACCCATTAGAACAGAGAATAAATAGAACTACATTTCTTGCA
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Primary source |
RefSeq : NM_001127705.1 (GI:189163537)
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Name |
Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (SERPINA1), transcript variant 9
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Type of transcript |
mRNA
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Organism |
Homo sapiens
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Length |
3510 nt
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Map |
14q32.1
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Location |
Chromosome 14 (NC_000014.8) strand : -
94843083...94844976 | 94845800...94845947 | 94847207...94847477 | 94848928...94849577 |
94854896...94854996 | 94855137...94855346 | 94856793...94857028 |
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Exon(s) |
Start |
End |
Length |
is coding |
Exon 1a
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1
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236
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236
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1
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Exon 2b
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237
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446
|
210
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1
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Exon 2e
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447
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547
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101
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1
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Exon 3
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548
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1197
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650
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1
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Exon 4
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1198
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1468
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271
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1
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Exon 5
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1469
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1616
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148
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1
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Exon 6
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1617
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3510
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1894
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1
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ID |
Class |
Location |
Mutation |
Length |
is synonymous |
Source |
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Primary source |
NCBI : CCDS9925
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Nucleotide |
SERPINA1, mRNA isoform 9[NM_001127705.1] : 552...1808
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Length |
1257
|
Location |
Chromosome 14 (NC_000014.8) strand : -
94844785...94844976 | 94845800...94845947 | 94847207...94847477 | 94848928...94849573 |
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Start codon |
1
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Translation |
NP_001121177.1 |
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1 |
TGGGCAGGAA |
CTGGGCACTG |
TGCCCAGGGC |
ATGCACTGCC |
TCCACGCAGC |
AACCCTCAGA |
GTCCTGAGCT |
GAACCAAGAA |
|
81 |
GGAGGAGGGG |
GTCGGGCCTC |
CGAGGAAGGC |
CTAGCCGCTG |
CTGCTGCCAG |
GAATTCCAGG |
TTGGAGGGGC |
GGCAACCTCC |
|
161 |
TGCCAGCCTT |
CAGGCCACTC |
TCCTGTGCCT |
GCCAGAAGAG |
ACAGAGCTTG |
AGGAGAGCTT |
GAGGAGAGCA |
GGAAAGGGCG |
|
241 |
GCAGTAAGTC |
TTCAGCATCA |
GGCATTTTGG |
GGTGACTCAG |
TAAATGGTAG |
ATCTTGCTAC |
CAGTGGAACA |
GCCACTAAGG |
|
321 |
ATTCTGCAGT |
GAGAGCAGAG |
GGCCAGCTAA |
GTGGTACTCT |
CCCAGAGACT |
GTCTGACTCA |
CGCCACCCCC |
TCCACCTTGG |
|
401 |
ACACAGGACG |
CTGTGGTTTC |
TGAGCCAGGT |
ACAATGACTC |
CTTTCGCCTC |
CCCCGTTGCC |
CCTCTGGATC |
CACTGCTTAA |
|
481 |
ATACGGACGA |
GGACAGGGCC |
CTGTCTCCTC |
AGCTTCAGGC |
ACCACCACTG |
ACCTGGGACA |
GTGAATCGAC |
AATGCCGTCT |
|
561 |
TCTGTCTCGT |
GGGGCATCCT |
CCTGCTGGCA |
GGCCTGTGCT |
GCCTGGTCCC |
TGTCTCCCTG |
GCTGAGGATC |
CCCAGGGAGA |
|
641 |
TGCTGCCCAG |
AAGACAGATA |
CATCCCACCA |
TGATCAGGAT |
CACCCAACCT |
TCAACAAGAT |
CACCCCCAAC |
CTGGCTGAGT |
|
721 |
TCGCCTTCAG |
CCTATACCGC |
CAGCTGGCAC |
ACCAGTCCAA |
CAGCACCAAT |
ATCTTCTTCT |
CCCCAGTGAG |
CATCGCTACA |
|
801 |
GCCTTTGCAA |
TGCTCTCCCT |
GGGGACCAAG |
GCTGACACTC |
ACGATGAAAT |
CCTGGAGGGC |
CTGAATTTCA |
ACCTCACGGA |
|
881 |
GATTCCGGAG |
GCTCAGATCC |
ATGAAGGCTT |
CCAGGAACTC |
CTCCGTACCC |
TCAACCAGCC |
AGACAGCCAG |
CTCCAGCTGA |
|
961 |
CCACCGGCAA |
TGGCCTGTTC |
CTCAGCGAGG |
GCCTGAAGCT |
AGTGGATAAG |
TTTTTGGAGG |
ATGTTAAAAA |
GTTGTACCAC |
|
1041 |
TCAGAAGCCT |
TCACTGTCAA |
CTTCGGGGAC |
ACCGAAGAGG |
CCAAGAAACA |
GATCAACGAT |
TACGTGGAGA |
AGGGTACTCA |
|
1121 |
AGGGAAAATT |
GTGGATTTGG |
TCAAGGAGCT |
TGACAGAGAC |
ACAGTTTTTG |
CTCTGGTGAA |
TTACATCTTC |
TTTAAAGGCA |
|
1201 |
AATGGGAGAG |
ACCCTTTGAA |
GTCAAGGACA |
CCGAGGAAGA |
GGACTTCCAC |
GTGGACCAGG |
TGACCACCGT |
GAAGGTGCCT |
|
1281 |
ATGATGAAGC |
GTTTAGGCAT |
GTTTAACATC |
CAGCACTGTA |
AGAAGCTGTC |
CAGCTGGGTG |
CTGCTGATGA |
AATACCTGGG |
|
1361 |
CAATGCCACC |
GCCATCTTCT |
TCCTGCCTGA |
TGAGGGGAAA |
CTACAGCACC |
TGGAAAATGA |
ACTCACCCAC |
GATATCATCA |
|
1441 |
CCAAGTTCCT |
GGAAAATGAA |
GACAGAAGGT |
CTGCCAGCTT |
ACATTTACCC |
AAACTGTCCA |
TTACTGGAAC |
CTATGATCTG |
|
1521 |
AAGAGCGTCC |
TGGGTCAACT |
GGGCATCACT |
AAGGTCTTCA |
GCAATGGGGC |
TGACCTCTCC |
GGGGTCACAG |
AGGAGGCACC |
|
1601 |
CCTGAAGCTC |
TCCAAGGCCG |
TGCATAAGGC |
TGTGCTGACC |
ATCGACGAGA |
AAGGGACTGA |
AGCTGCTGGG |
GCCATGTTTT |
|
1681 |
TAGAGGCCAT |
ACCCATGTCT |
ATCCCCCCCG |
AGGTCAAGTT |
CAACAAACCC |
TTTGTCTTCT |
TAATGATTGA |
ACAAAATACC |
|
1761 |
AAGTCTCCCC |
TCTTCATGGG |
AAAAGTGGTG |
AATCCCACCC |
AAAAATAACT |
GCCTCTCGCT |
CCTCAACCCC |
TCCCCTCCAT |
|
1841 |
CCCTGGCCCC |
CTCCCTGGAT |
GACATTAAAG |
AAGGGTTGAG |
CTGGTCCCTG |
CCTGCATGTG |
ACTGTAAATC |
CCTCCCATGT |
|
1921 |
TTTCTCTGAG |
TCTCCCTTTG |
CCTGCTGAGG |
CTGTATGTGG |
GCTCCAGGTA |
ACAGTGCTGT |
CTTCGGGCCC |
CCTGAACTGT |
|
2001 |
GTTCATGGAG |
CATCTGGCTG |
GGTAGGCACA |
TGCTGGGCTT |
GAATCCAGGG |
GGGACTGAAT |
CCTCAGCTTA |
CGGACCTGGG |
|
2081 |
CCCATCTGTT |
TCTGGAGGGC |
TCCAGTCTTC |
CTTGTCCTGT |
CTTGGAGTCC |
CCAAGAAGGA |
ATCACAGGGG |
AGGAACCAGA |
|
2161 |
TACCAGCCAT |
GACCCCAGGC |
TCCACCAAGC |
ATCTTCATGT |
CCCCCTGCTC |
ATCCCCCACT |
CCCCCCCACC |
CAGAGTTGCT |
|
2241 |
CATCCTGCCA |
GGGCTGGCTG |
TGCCCACCCC |
AAGGCTGCCC |
TCCTGGGGGC |
CCCAGAACTG |
CCTGATCGTG |
CCGTGGCCCA |
|
2321 |
GTTTTGTGGC |
ATCTGCAGCA |
ACACAAGAGA |
GAGGACAATG |
TCCTCCTCTT |
GACCCGCTGT |
CACCTAACCA |
GACTCGGGCC |
|
2401 |
CTGCACCTCT |
CAGGCACTTC |
TGGAAAATGA |
CTGAGGCAGA |
TTCTTCCTGA |
AGCCCATTCT |
CCATGGGGCA |
ACAAGGACAC |
|
2481 |
CTATTCTGTC |
CTTGTCCTTC |
CATCGCTGCC |
CCAGAAAGCC |
TCACATATCT |
CCGTTTAGAA |
TCAGGTCCCT |
TCTCCCCAGA |
|
2561 |
TGAAGAGGAG |
GGTCTCTGCT |
TTGTTTTCTC |
TATCTCCTCC |
TCAGACTTGA |
CCAGGCCCAG |
CAGGCCCCAG |
AAGACCATTA |
|
2641 |
CCCTATATCC |
CTTCTCCTCC |
CTAGTCACAT |
GGCCATAGGC |
CTGCTGATGG |
CTCAGGAAGG |
CCATTGCAAG |
GACTCCTCAG |
|
2721 |
CTATGGGAGA |
GGAAGCACAT |
CACCCATTGA |
CCCCCGCAAC |
CCCTCCCTTT |
CCTCCTCTGA |
GTCCCGACTG |
GGGCCACATG |
|
2801 |
CAGCCTGACT |
TCTTTGTGCC |
TGTTGCTGTC |
CCTGCAGTCT |
TCAGAGGGCC |
ACCGCAGCTC |
CAGTGCCACG |
GCAGGAGGCT |
|
2881 |
GTTCCTGAAT |
AGCCCCTGTG |
GTAAGGGCCA |
GGAGAGTCCT |
TCCATCCTCC |
AAGGCCCTGC |
TAAAGGACAC |
AGCAGCCAGG |
|
2961 |
AAGTCCCCTG |
GGCCCCTAGC |
TGAAGGACAG |
CCTGCTCCCT |
CCGTCTCTAC |
CAGGAATGGC |
CTTGTCCTAT |
GGAAGGCACT |
|
3041 |
GCCCCATCCC |
AAACTAATCT |
AGGAATCACT |
GTCTAACCAC |
TCACTGTCAT |
GAATGTGTAC |
TTAAAGGATG |
AGGTTGAGTC |
|
3121 |
ATACCAAATA |
GTGATTTCGA |
TAGTTCAAAA |
TGGTGAAATT |
AGCAATTCTA |
CATGATTCAG |
TCTAATCAAT |
GGATACCGAC |
|
3201 |
TGTTTCCCAC |
ACAAGTCTCC |
TGTTCTCTTA |
AGCTTACTCA |
CTGACAGCCT |
TTCACTCTCC |
ACAAATACAT |
TAAAGATATG |
|
3281 |
GCCATCACCA |
AGCCCCCTAG |
GATGACACCA |
GACCTGAGAG |
TCTGAAGACC |
TGGATCCAAG |
TTCTGACTTT |
TCCCCCTGAC |
|
3361 |
AGCTGTGTGA |
CCTTCGTGAA |
GTCGCCAAAC |
CTCTCTGAGC |
CCCAGTCATT |
GCTAGTAAGA |
CCTGCCTTTG |
AGTTGGTATG |
|
3441 |
ATGTTCAAGT |
TAGATAACAA |
AATGTTTATA |
CCCATTAGAA |
CAGAGAATAA |
ATAGAACTAC |
ATTTCTTGCA |
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>gi|189163537|ref|NM_001127705.1|Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (SERPINA1), transcript variant 9
TGGGCAGGAACTGGGCACTGTGCCCAGGGCATGCACTGCCTCCACGCAGCAACCCTCAGAGTCCTGAGCTGAACCAAGAA
GGAGGAGGGGGTCGGGCCTCCGAGGAAGGCCTAGCCGCTGCTGCTGCCAGGAATTCCAGGTTGGAGGGGCGGCAACCTCC
TGCCAGCCTTCAGGCCACTCTCCTGTGCCTGCCAGAAGAGACAGAGCTTGAGGAGAGCTTGAGGAGAGCAGGAAAGGGCG
GCAGTAAGTCTTCAGCATCAGGCATTTTGGGGTGACTCAGTAAATGGTAGATCTTGCTACCAGTGGAACAGCCACTAAGG
ATTCTGCAGTGAGAGCAGAGGGCCAGCTAAGTGGTACTCTCCCAGAGACTGTCTGACTCACGCCACCCCCTCCACCTTGG
ACACAGGACGCTGTGGTTTCTGAGCCAGGTACAATGACTCCTTTCGCCTCCCCCGTTGCCCCTCTGGATCCACTGCTTAA
ATACGGACGAGGACAGGGCCCTGTCTCCTCAGCTTCAGGCACCACCACTGACCTGGGACAGTGAATCGACAATGCCGTCT
TCTGTCTCGTGGGGCATCCTCCTGCTGGCAGGCCTGTGCTGCCTGGTCCCTGTCTCCCTGGCTGAGGATCCCCAGGGAGA
TGCTGCCCAGAAGACAGATACATCCCACCATGATCAGGATCACCCAACCTTCAACAAGATCACCCCCAACCTGGCTGAGT
TCGCCTTCAGCCTATACCGCCAGCTGGCACACCAGTCCAACAGCACCAATATCTTCTTCTCCCCAGTGAGCATCGCTACA
GCCTTTGCAATGCTCTCCCTGGGGACCAAGGCTGACACTCACGATGAAATCCTGGAGGGCCTGAATTTCAACCTCACGGA
GATTCCGGAGGCTCAGATCCATGAAGGCTTCCAGGAACTCCTCCGTACCCTCAACCAGCCAGACAGCCAGCTCCAGCTGA
CCACCGGCAATGGCCTGTTCCTCAGCGAGGGCCTGAAGCTAGTGGATAAGTTTTTGGAGGATGTTAAAAAGTTGTACCAC
TCAGAAGCCTTCACTGTCAACTTCGGGGACACCGAAGAGGCCAAGAAACAGATCAACGATTACGTGGAGAAGGGTACTCA
AGGGAAAATTGTGGATTTGGTCAAGGAGCTTGACAGAGACACAGTTTTTGCTCTGGTGAATTACATCTTCTTTAAAGGCA
AATGGGAGAGACCCTTTGAAGTCAAGGACACCGAGGAAGAGGACTTCCACGTGGACCAGGTGACCACCGTGAAGGTGCCT
ATGATGAAGCGTTTAGGCATGTTTAACATCCAGCACTGTAAGAAGCTGTCCAGCTGGGTGCTGCTGATGAAATACCTGGG
CAATGCCACCGCCATCTTCTTCCTGCCTGATGAGGGGAAACTACAGCACCTGGAAAATGAACTCACCCACGATATCATCA
CCAAGTTCCTGGAAAATGAAGACAGAAGGTCTGCCAGCTTACATTTACCCAAACTGTCCATTACTGGAACCTATGATCTG
AAGAGCGTCCTGGGTCAACTGGGCATCACTAAGGTCTTCAGCAATGGGGCTGACCTCTCCGGGGTCACAGAGGAGGCACC
CCTGAAGCTCTCCAAGGCCGTGCATAAGGCTGTGCTGACCATCGACGAGAAAGGGACTGAAGCTGCTGGGGCCATGTTTT
TAGAGGCCATACCCATGTCTATCCCCCCCGAGGTCAAGTTCAACAAACCCTTTGTCTTCTTAATGATTGAACAAAATACC
AAGTCTCCCCTCTTCATGGGAAAAGTGGTGAATCCCACCCAAAAATAACTGCCTCTCGCTCCTCAACCCCTCCCCTCCAT
CCCTGGCCCCCTCCCTGGATGACATTAAAGAAGGGTTGAGCTGGTCCCTGCCTGCATGTGACTGTAAATCCCTCCCATGT
TTTCTCTGAGTCTCCCTTTGCCTGCTGAGGCTGTATGTGGGCTCCAGGTAACAGTGCTGTCTTCGGGCCCCCTGAACTGT
GTTCATGGAGCATCTGGCTGGGTAGGCACATGCTGGGCTTGAATCCAGGGGGGACTGAATCCTCAGCTTACGGACCTGGG
CCCATCTGTTTCTGGAGGGCTCCAGTCTTCCTTGTCCTGTCTTGGAGTCCCCAAGAAGGAATCACAGGGGAGGAACCAGA
TACCAGCCATGACCCCAGGCTCCACCAAGCATCTTCATGTCCCCCTGCTCATCCCCCACTCCCCCCCACCCAGAGTTGCT
CATCCTGCCAGGGCTGGCTGTGCCCACCCCAAGGCTGCCCTCCTGGGGGCCCCAGAACTGCCTGATCGTGCCGTGGCCCA
GTTTTGTGGCATCTGCAGCAACACAAGAGAGAGGACAATGTCCTCCTCTTGACCCGCTGTCACCTAACCAGACTCGGGCC
CTGCACCTCTCAGGCACTTCTGGAAAATGACTGAGGCAGATTCTTCCTGAAGCCCATTCTCCATGGGGCAACAAGGACAC
CTATTCTGTCCTTGTCCTTCCATCGCTGCCCCAGAAAGCCTCACATATCTCCGTTTAGAATCAGGTCCCTTCTCCCCAGA
TGAAGAGGAGGGTCTCTGCTTTGTTTTCTCTATCTCCTCCTCAGACTTGACCAGGCCCAGCAGGCCCCAGAAGACCATTA
CCCTATATCCCTTCTCCTCCCTAGTCACATGGCCATAGGCCTGCTGATGGCTCAGGAAGGCCATTGCAAGGACTCCTCAG
CTATGGGAGAGGAAGCACATCACCCATTGACCCCCGCAACCCCTCCCTTTCCTCCTCTGAGTCCCGACTGGGGCCACATG
CAGCCTGACTTCTTTGTGCCTGTTGCTGTCCCTGCAGTCTTCAGAGGGCCACCGCAGCTCCAGTGCCACGGCAGGAGGCT
GTTCCTGAATAGCCCCTGTGGTAAGGGCCAGGAGAGTCCTTCCATCCTCCAAGGCCCTGCTAAAGGACACAGCAGCCAGG
AAGTCCCCTGGGCCCCTAGCTGAAGGACAGCCTGCTCCCTCCGTCTCTACCAGGAATGGCCTTGTCCTATGGAAGGCACT
GCCCCATCCCAAACTAATCTAGGAATCACTGTCTAACCACTCACTGTCATGAATGTGTACTTAAAGGATGAGGTTGAGTC
ATACCAAATAGTGATTTCGATAGTTCAAAATGGTGAAATTAGCAATTCTACATGATTCAGTCTAATCAATGGATACCGAC
TGTTTCCCACACAAGTCTCCTGTTCTCTTAAGCTTACTCACTGACAGCCTTTCACTCTCCACAAATACATTAAAGATATG
GCCATCACCAAGCCCCCTAGGATGACACCAGACCTGAGAGTCTGAAGACCTGGATCCAAGTTCTGACTTTTCCCCCTGAC
AGCTGTGTGACCTTCGTGAAGTCGCCAAACCTCTCTGAGCCCCAGTCATTGCTAGTAAGACCTGCCTTTGAGTTGGTATG
ATGTTCAAGTTAGATAACAAAATGTTTATACCCATTAGAACAGAGAATAAATAGAACTACATTTCTTGCA
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Exon number |
2c
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Length |
257 nt
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Location |
Chromosome 14 (NC_000014.8) : 94854896...94855152 (-)
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Is part of |
SERPINA1, mRNA isoform 1
(NM_000295.4)
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Sequence |
Show
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ACAATGACTCCTTTCGGTAAGTGCAGTGGAAGCTGTACACTGCCCAGGCAAAGCGTCCGGGCAGCGTAGGCGGGCGACTC
AGATCCCAGCCAGTGGACTTAGCCCCTGTTTGCTCCTCCGATAACTGGGGTGACCTTGGTTAATATTCACCAGCAGCCTC
CCCCGTTGCCCCTCTGGATCCACTGCTTAAATACGGACGAGGACAGGGCCCTGTCTCCTCAGCTTCAGGCACCACCACTG
ACCTGGGACAGTGAATC
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Exon number |
3
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Length |
650 nt
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Location |
Chromosome 14 (NC_000014.8) : 94848928...94849577 (-)
|
Is part of |
SERPINA1, mRNA isoform 6
(NM_001127702.1)
SERPINA1, mRNA isoform 8
(NM_001127704.1)
SERPINA1, mRNA isoform 11
(NM_001127707.1)
SERPINA1, mRNA isoform 10
(NM_001127706.1)
SERPINA1, mRNA isoform 5
(NM_001127701.1)
SERPINA1, mRNA isoform 2
(NM_001002236.2)
SERPINA1, mRNA isoform 1
(NM_000295.4)
SERPINA1, mRNA isoform 9
(NM_001127705.1)
SERPINA1, mRNA isoform 7
(NM_001127703.1)
SERPINA1, mRNA isoform 3
(NM_001002235.2)
SERPINA1, mRNA isoform 4
(NM_001127700.1)
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Sequence |
Show
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GACAATGCCGTCTTCTGTCTCGTGGGGCATCCTCCTGCTGGCAGGCCTGTGCTGCCTGGTCCCTGTCTCCCTGGCTGAGG
ATCCCCAGGGAGATGCTGCCCAGAAGACAGATACATCCCACCATGATCAGGATCACCCAACCTTCAACAAGATCACCCCC
AACCTGGCTGAGTTCGCCTTCAGCCTATACCGCCAGCTGGCACACCAGTCCAACAGCACCAATATCTTCTTCTCCCCAGT
GAGCATCGCTACAGCCTTTGCAATGCTCTCCCTGGGGACCAAGGCTGACACTCACGATGAAATCCTGGAGGGCCTGAATT
TCAACCTCACGGAGATTCCGGAGGCTCAGATCCATGAAGGCTTCCAGGAACTCCTCCGTACCCTCAACCAGCCAGACAGC
CAGCTCCAGCTGACCACCGGCAATGGCCTGTTCCTCAGCGAGGGCCTGAAGCTAGTGGATAAGTTTTTGGAGGATGTTAA
AAAGTTGTACCACTCAGAAGCCTTCACTGTCAACTTCGGGGACACCGAAGAGGCCAAGAAACAGATCAACGATTACGTGG
AGAAGGGTACTCAAGGGAAAATTGTGGATTTGGTCAAGGAGCTTGACAGAGACACAGTTTTTGCTCTGGTGAATTACATC
TTCTTTAAAG
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Exon number |
4
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Length |
271 nt
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Location |
Chromosome 14 (NC_000014.8) : 94847207...94847477 (-)
|
Is part of |
SERPINA1, mRNA isoform 6
(NM_001127702.1)
SERPINA1, mRNA isoform 8
(NM_001127704.1)
SERPINA1, mRNA isoform 11
(NM_001127707.1)
SERPINA1, mRNA isoform 10
(NM_001127706.1)
SERPINA1, mRNA isoform 5
(NM_001127701.1)
SERPINA1, mRNA isoform 2
(NM_001002236.2)
SERPINA1, mRNA isoform 1
(NM_000295.4)
SERPINA1, mRNA isoform 9
(NM_001127705.1)
SERPINA1, mRNA isoform 7
(NM_001127703.1)
SERPINA1, mRNA isoform 3
(NM_001002235.2)
SERPINA1, mRNA isoform 4
(NM_001127700.1)
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Sequence |
Show
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GCAAATGGGAGAGACCCTTTGAAGTCAAGGACACCGAGGAAGAGGACTTCCACGTGGACCAGGTGACCACCGTGAAGGTG
CCTATGATGAAGCGTTTAGGCATGTTTAACATCCAGCACTGTAAGAAGCTGTCCAGCTGGGTGCTGCTGATGAAATACCT
GGGCAATGCCACCGCCATCTTCTTCCTGCCTGATGAGGGGAAACTACAGCACCTGGAAAATGAACTCACCCACGATATCA
TCACCAAGTTCCTGGAAAATGAAGACAGAAG
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Exon number |
5
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Length |
148 nt
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Location |
Chromosome 14 (NC_000014.8) : 94845800...94845947 (-)
|
Is part of |
SERPINA1, mRNA isoform 6
(NM_001127702.1)
SERPINA1, mRNA isoform 8
(NM_001127704.1)
SERPINA1, mRNA isoform 11
(NM_001127707.1)
SERPINA1, mRNA isoform 10
(NM_001127706.1)
SERPINA1, mRNA isoform 5
(NM_001127701.1)
SERPINA1, mRNA isoform 2
(NM_001002236.2)
SERPINA1, mRNA isoform 1
(NM_000295.4)
SERPINA1, mRNA isoform 9
(NM_001127705.1)
SERPINA1, mRNA isoform 7
(NM_001127703.1)
SERPINA1, mRNA isoform 3
(NM_001002235.2)
SERPINA1, mRNA isoform 4
(NM_001127700.1)
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Sequence |
Show
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GTCTGCCAGCTTACATTTACCCAAACTGTCCATTACTGGAACCTATGATCTGAAGAGCGTCCTGGGTCAACTGGGCATCA
CTAAGGTCTTCAGCAATGGGGCTGACCTCTCCGGGGTCACAGAGGAGGCACCCCTGAAGCTCTCCAAG
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Exon number |
6
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Length |
1894 nt
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Location |
Chromosome 14 (NC_000014.8) : 94843083...94844976 (-)
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Is part of |
SERPINA1, mRNA isoform 6
(NM_001127702.1)
SERPINA1, mRNA isoform 8
(NM_001127704.1)
SERPINA1, mRNA isoform 11
(NM_001127707.1)
SERPINA1, mRNA isoform 10
(NM_001127706.1)
SERPINA1, mRNA isoform 5
(NM_001127701.1)
SERPINA1, mRNA isoform 2
(NM_001002236.2)
SERPINA1, mRNA isoform 1
(NM_000295.4)
SERPINA1, mRNA isoform 9
(NM_001127705.1)
SERPINA1, mRNA isoform 7
(NM_001127703.1)
SERPINA1, mRNA isoform 3
(NM_001002235.2)
SERPINA1, mRNA isoform 4
(NM_001127700.1)
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Sequence |
Show
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GCCGTGCATAAGGCTGTGCTGACCATCGACGAGAAAGGGACTGAAGCTGCTGGGGCCATGTTTTTAGAGGCCATACCCAT
GTCTATCCCCCCCGAGGTCAAGTTCAACAAACCCTTTGTCTTCTTAATGATTGAACAAAATACCAAGTCTCCCCTCTTCA
TGGGAAAAGTGGTGAATCCCACCCAAAAATAACTGCCTCTCGCTCCTCAACCCCTCCCCTCCATCCCTGGCCCCCTCCCT
GGATGACATTAAAGAAGGGTTGAGCTGGTCCCTGCCTGCATGTGACTGTAAATCCCTCCCATGTTTTCTCTGAGTCTCCC
TTTGCCTGCTGAGGCTGTATGTGGGCTCCAGGTAACAGTGCTGTCTTCGGGCCCCCTGAACTGTGTTCATGGAGCATCTG
GCTGGGTAGGCACATGCTGGGCTTGAATCCAGGGGGGACTGAATCCTCAGCTTACGGACCTGGGCCCATCTGTTTCTGGA
GGGCTCCAGTCTTCCTTGTCCTGTCTTGGAGTCCCCAAGAAGGAATCACAGGGGAGGAACCAGATACCAGCCATGACCCC
AGGCTCCACCAAGCATCTTCATGTCCCCCTGCTCATCCCCCACTCCCCCCCACCCAGAGTTGCTCATCCTGCCAGGGCTG
GCTGTGCCCACCCCAAGGCTGCCCTCCTGGGGGCCCCAGAACTGCCTGATCGTGCCGTGGCCCAGTTTTGTGGCATCTGC
AGCAACACAAGAGAGAGGACAATGTCCTCCTCTTGACCCGCTGTCACCTAACCAGACTCGGGCCCTGCACCTCTCAGGCA
CTTCTGGAAAATGACTGAGGCAGATTCTTCCTGAAGCCCATTCTCCATGGGGCAACAAGGACACCTATTCTGTCCTTGTC
CTTCCATCGCTGCCCCAGAAAGCCTCACATATCTCCGTTTAGAATCAGGTCCCTTCTCCCCAGATGAAGAGGAGGGTCTC
TGCTTTGTTTTCTCTATCTCCTCCTCAGACTTGACCAGGCCCAGCAGGCCCCAGAAGACCATTACCCTATATCCCTTCTC
CTCCCTAGTCACATGGCCATAGGCCTGCTGATGGCTCAGGAAGGCCATTGCAAGGACTCCTCAGCTATGGGAGAGGAAGC
ACATCACCCATTGACCCCCGCAACCCCTCCCTTTCCTCCTCTGAGTCCCGACTGGGGCCACATGCAGCCTGACTTCTTTG
TGCCTGTTGCTGTCCCTGCAGTCTTCAGAGGGCCACCGCAGCTCCAGTGCCACGGCAGGAGGCTGTTCCTGAATAGCCCC
TGTGGTAAGGGCCAGGAGAGTCCTTCCATCCTCCAAGGCCCTGCTAAAGGACACAGCAGCCAGGAAGTCCCCTGGGCCCC
TAGCTGAAGGACAGCCTGCTCCCTCCGTCTCTACCAGGAATGGCCTTGTCCTATGGAAGGCACTGCCCCATCCCAAACTA
ATCTAGGAATCACTGTCTAACCACTCACTGTCATGAATGTGTACTTAAAGGATGAGGTTGAGTCATACCAAATAGTGATT
TCGATAGTTCAAAATGGTGAAATTAGCAATTCTACATGATTCAGTCTAATCAATGGATACCGACTGTTTCCCACACAAGT
CTCCTGTTCTCTTAAGCTTACTCACTGACAGCCTTTCACTCTCCACAAATACATTAAAGATATGGCCATCACCAAGCCCC
CTAGGATGACACCAGACCTGAGAGTCTGAAGACCTGGATCCAAGTTCTGACTTTTCCCCCTGACAGCTGTGTGACCTTCG
TGAAGTCGCCAAACCTCTCTGAGCCCCAGTCATTGCTAGTAAGACCTGCCTTTGAGTTGGTATGATGTTCAAGTTAGATA
ACAAAATGTTTATACCCATTAGAACAGAGAATAAATAGAACTACATTTCTTGCA
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Primary source |
Uniprot : P01009
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Name |
Alpha-1-antitrypsin
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Alternative name(s) |
Alpha-1 protease inhibitor Alpha-1-antiproteinase Serpin A1
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Synonym(s) |
SPAAT
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Organism |
Homo sapiens
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Length |
418 aa
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Protein existence |
---
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General annotation (Comments)
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top
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Domain
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The reactive center loop (RCL) extends out from the body of the protein and directs binding to the target protease. The protease cleaves the serpin at the reactive site within the RCL, establishing a covalent linkage between the carboxyl group of the serpin reactive site and the serine hydroxyl of the protease. The resulting inactive serpin-protease complex is highly stable.
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Function
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Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin.
Short peptide from AAT (SPAAT) is a reversible chymotrypsin inhibitor. It also inhibits elastase, but not trypsin. Its major physiological function is the protection of the lower respiratory tract against proteolytic destruction by human leukocyte elastase (HLE).
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Polymorphism
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The sequence shown is that of the M1V allele which is the most common form of PI (44 to 49%). Other frequent alleles are: M1A 20 to 23%; M2 10 to 11%; M3 14 to 19%.
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Ptm
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Several isomers are observed, resulting from the combination of different N-linked glycan structures and mature N-terminus. N- linked glycan at Asn-107 is alternatively di-antennary, tri- antennary or tetra-antennary, whereas glycan at Asn-70 is di- antennary with trace amounts of tri-antennary, and glycan at Asn- 271 is exclusively di-antennary. The structure of the antennas is Neu5Ac(alpha1-6)Gal(beta1-4)GlcNAc attached to the core structure Man(alpha1-6)[Man(alpha1-3)]Man(beta1-4)GlcNAc(beta1-4)GlcNAc. Some antennas are fucosylated, which forms a Lewis-X determinant.
Proteolytic processing may yield the truncated form that ranges from Asp-30 to Lys-418.
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Similarity
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Belongs to the serpin family.
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Subcellular location
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Secreted.
Short peptide from AAT: Secreted, extracellular space, extracellular matrix.
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Tissue specificity
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Plasma.
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Biological process
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acute-phase response [GO:0006953]
blood coagulation [GO:0007596]
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Cellular component
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proteinaceous extracellular matrix [GO:0005578]
extracellular space [GO:0005615]
platelet alpha granule lumen [GO:0031093]
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Molecular function
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protease binding [GO:0002020]
serine-type endopeptidase inhibitor activity [GO:0004867]
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Alternative product(s)
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top
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Uniprot Identifier
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Difference(s) with the 'canonical' sequence
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Notes
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Sequences
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Isoform 1
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P01009-1
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---
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'Canonical' sequence
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Get Fasta
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Isoform 2
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P01009-2
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356-418 : AVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVF LMIEQNTKSPLFMGKVVNPTQK -> VRSP
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---
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Get Fasta
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Isoform 3
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P01009-3
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307-418 : Missing
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---
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Get Fasta
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Feature key |
Position
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Length
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Description
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Feature identifier
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Molecule processing |
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Peptide
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375 - 418
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44
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Short peptide from AAT
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PRO_0000364030
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Signal
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1 - 24
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24
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P01009-SIGNAL-1
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Region |
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Region
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368 - 392
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25
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RCL
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P01009-REGION-368
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Sites |
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Site
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382 - 383
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2
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Reactive bond
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P01009-SITE-382
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Natural variations |
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Natural variant site
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4 - 4
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1
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S -> L (in Z-Wrexham)
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VAR_006978
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Natural variant site
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26 - 26
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1
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D -> A (in V-Munich)
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VAR_006979
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Natural variant site
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37 - 37
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1
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T -> A (in dbSNP:rs11558262)
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VAR_051938
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Natural variant site
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58 - 58
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1
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A -> T (in M5-Karlsruhe)
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VAR_006980
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Natural variant site
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63 - 63
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1
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R -> C (in I; dbSNP:rs28931570)
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VAR_006981
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Natural variant site
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65 - 65
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1
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L -> P (in M-Procida; dbSNP:rs28931569)
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VAR_006982
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Natural variant site
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69 - 69
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1
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S -> F (in M6-Bonn)
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VAR_006983
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Natural variant site
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75 - 75
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1
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Missing (in M-Malton, M-Nichinan and M- Palermo; associated with very low serum levels of AAT; homozygosity for allele M- Malton may be associated with a risk for chronic emphysema or infantile liver cirrhosis)
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VAR_006984
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Natural variant site
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77 - 77
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1
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S -> F (in S-Iiyama; dbSNP:rs55819880)
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VAR_006985
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Natural variant site
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84 - 84
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1
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A -> T (in M6-Passau)
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VAR_006986
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Natural variant site
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91 - 91
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1
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G -> E (in M-Mineral springs; causes reduced AAT secretion; dbSNP:rs28931568)
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VAR_006987
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Natural variant site
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92 - 92
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1
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T -> I (in QO-Lisbon; deficient AAT with very low serum levels)
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VAR_006988
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Natural variant site
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109 - 109
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1
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T -> M (in Z-Bristol; deficient AA; disrupts the N-glycosylation site N-107)
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VAR_011620
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Natural variant site
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112 - 112
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1
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P -> T (in M5-Berlin)
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VAR_006989
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Natural variant site
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116 - 116
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1
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I -> N (in QO-Ludwigshafen; dbSNP:rs28931572)
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VAR_006990
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Natural variant site
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125 - 125
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1
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R -> H (in M2; associated with D-400; dbSNP:rs709932)
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VAR_006991
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Natural variant site
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139 - 139
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1
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G -> S (in QO-Newport; dbSNP:rs11558261)
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VAR_006992
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Natural variant site
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172 - 172
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1
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G -> R (in V and M-Nichinan)
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VAR_006993
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Natural variant site
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172 - 172
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1
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G -> W (in M2-Obernburg)
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VAR_006994
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Natural variant site
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180 - 180
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1
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Q -> E (in L-Frankfurt)
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VAR_006995
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Natural variant site
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190 - 198
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9
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QGKIVDLVK -> GFQNAILVR (in Aberrant form)
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VAR_036746
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Natural variant site
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228 - 228
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1
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E -> K (in X)
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VAR_006996
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Natural variant site
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237 - 237
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1
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V -> A (in M1A and Z; associated with K- 366 in Z; dbSNP:rs6647)
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VAR_006997
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Natural variant site
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247 - 247
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1
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R -> C (in F; dbSNP:rs28929470)
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VAR_006998
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Natural variant site
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280 - 280
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1
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D -> V (in P-Duarte/P-Cardiff/P-Lowell; associated with H-415 in Y-Barcelona; dbSNP:rs28929472)
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VAR_006999
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Natural variant site
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288 - 288
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1
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E -> V (in S and T; dbSNP:rs17580)
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VAR_007000
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Natural variant site
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305 - 305
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1
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Missing (in Basque)
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VAR_009216
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Natural variant site
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354 - 354
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1
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S -> F (in S-Munich)
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VAR_007001
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Natural variant site
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360 - 360
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1
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A -> T (in W-Bethesda; dbSNP:rs1802959)
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VAR_007002
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Natural variant site
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365 - 365
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1
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D -> N (in P-St.Albans/P-Donauwoerth)
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VAR_007003
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Natural variant site
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366 - 366
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1
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E -> K (in Z/Z-Augsburg/Z-Tun; associated with A-237 in Z; dbSNP:rs28929474)
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VAR_007004
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Natural variant site
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382 - 382
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1
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M -> R (in Pittsburgh; has antithrombin activity; causes fatal bleeding diathesis)
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VAR_007005
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Natural variant site
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386 - 386
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1
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P -> T (in L-Offenbach)
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VAR_007007
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Natural variant site
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386 - 386
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1
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P -> H (in Sao Tome)
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VAR_007006
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Natural variant site
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387 - 387
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1
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E -> K (in Christchurch)
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VAR_007008
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Natural variant site
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393 - 393
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1
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P -> L (in M-Heerlen)
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VAR_007009
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Natural variant site
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400 - 400
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1
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E -> D (in M2 and M3; associated with H- 125 in M2; dbSNP:rs1303)
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VAR_007010
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Natural variant site
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415 - 415
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1
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P -> H (in Y-Barcelona; associated with V-280)
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VAR_007011
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Alternative sequence
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307 - 418
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112
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Missing
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VSP_028890
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Alternative sequence
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356 - 418
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63
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AVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVF LMIEQNTKSPLFMGKVVNPTQK -> VRSP
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VSP_028889
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Amino acid modifications |
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Glycosylation
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70 - 70
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1
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N-linked (GlcNAc...) (complex)
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P01009-CARBOHYD-70
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Glycosylation
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107 - 107
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1
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N-linked (GlcNAc...) (complex)
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P01009-CARBOHYD-107
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Glycosylation
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271 - 271
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1
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N-linked (GlcNAc...) (complex)
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P01009-CARBOHYD-271
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Modified residue
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256 - 256
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1
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S-cysteinyl cysteine
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P01009-MOD_RES-256
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Experimental info |
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Mutagenesis
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382 - 382
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1
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M->V: Oxidation-resistant inhibitor of therapeutic importance
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P01009-MUTAGEN-382
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1 |
MPSSVSWGIL |
LLAGLCCLVP |
VSLAEDPQGD |
AAQKTDTSHH |
DQDHPTFNKI |
TPNLAEFAFS |
LYRQLAHQSN |
STNIFFSPVS |
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81 |
IATAFAMLSL |
GTKADTHDEI |
LEGLNFNLTE |
IPEAQIHEGF |
QELLRTLNQP |
DSQLQLTTGN |
GLFLSEGLKL |
VDKFLEDVKK |
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161 |
LYHSEAFTVN |
FGDTEEAKKQ |
INDYVEKGTQ |
GKIVDLVKEL |
DRDTVFALVN |
YIFFKGKWER |
PFEVKDTEEE |
DFHVDQVTTV |
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241 |
KVPMMKRLGM |
FNIQHCKKLS |
SWVLLMKYLG |
NATAIFFLPD |
EGKLQHLENE |
LTHDIITKFL |
ENEDRRSASL |
HLPKLSITGT |
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321 |
YDLKSVLGQL |
GITKVFSNGA |
DLSGVTEEAP |
LKLSKAVHKA |
VLTIDEKGTE |
AAGAMFLEAI |
PMSIPPEVKF |
NKPFVFLMIE |
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401 |
QNTKSPLFMG |
KVVNPTQK |
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>sp|P01009|A1AT_human Alpha-1-antitrypsin
MPSSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQSNSTNIFFSPVS
IATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKK
LYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTV
KVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLENEDRRSASLHLPKLSITGT
YDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIE
QNTKSPLFMGKVVNPTQK
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