(PRKAR1A) protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) [Homo sapiens] |
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Gene
Transcript(s)
Exon(s)
Protein(s)
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Accession
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9843
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Official symbol
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PRKAR1A
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Official name
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protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
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Gene type
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gene with protein product
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Organism
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Homo sapiens
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Location
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Chromosome 17 (NC_000017.10) : 66508109...66528910 (+)
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Map
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17q23-q24
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Length
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20802 nt
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NM_002734.3
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PRKAR1A, mRNA isoform 1
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NM_212471.1
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PRKAR1A, mRNA isoform 2
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NM_212472.1
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PRKAR1A, mRNA isoform 3
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Accession
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Name
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Organism
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Length
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P10644
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cAMP-dependent protein kinase type I-alpha regulatory subunit
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Homo sapiens
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381 aa
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B2R5T5
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Protein kinase, cAMP-dependent, regulatory, type I, alpha (Tissue specific extinguisher 1), isoform CRA_a [submitted name]
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Homo sapiens
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381 aa
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Synonyms |
PPNAD1; PKR1; MGC17251; DKFZp779L0468; CNC1; CNC; CAR; TSE1; PRKAR1
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Alternative name(s) |
protein kinase A type 1a regulatory subunit; cAMP-dependent protein kinase regulatory subunit RIalpha; cAMP-dependent protein kinase type I-alpha regulatory chain; tissue-specific extinguisher 1
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Summary |
cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. This gene encodes one of the regulatory subunits. This protein was found to be a tissue-specific extinguisher that down-regulates the expression of seven liver genes in hepatoma x fibroblast hybrids. Mutations in this gene cause Carney complex (CNC). This gene can fuse to the RET protooncogene by gene rearrangement and form the thyroid tumor-specific chimeric oncogene known as PTC2. A nonconventional nuclear localization sequence (NLS) has been found for this protein which suggests a role in DNA replication via the protein serving as a nuclear transport protein for the second subunit of the Replication Factor C (RFC40). Three alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq].
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Related Articles in PubMed
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Go to ensembl
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1 |
CAGGGAGGGG |
GTGGAAAGGA |
GGGAGAAAAG |
GCAGAGGCGT |
CAAGGGAGGC |
CGGAGGGAGA |
GTGGGGTGGA |
CAGAGGAGCG |
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81 |
GAGGGACGAG |
AGGGAAGCGC |
ACGATAGCTG |
CGCGGAGAGA |
GAGCGAAGAG |
CAGGCGGAGG |
AACAAAGGCG |
ACCCAAGACA |
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161 |
CCCAGAGAGG |
GACAGGTAAG |
GAGGGGCAGG |
TGAGCAGGAA |
GGAGGAGAGA |
ACCGGGCTAG |
GGAGACTGCG |
GAAAGGAGAA |
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241 |
GTGGCGGGCG |
TGAGGAAACT |
GCTGTGGATA |
AGGGACGAGT |
AAGATGGAAA |
GAATGGCGGA |
AGACGAACGA |
CCGCAGAGTG |
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321 |
AGGGTCCTTC |
CAAGAGCGAC |
CAGGGGGGAG |
GAACTGGGGC |
TGTTGCGCCC |
TTAAGGTTGC |
TAAGGCGACG |
GTTCTGGCCA |
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401 |
GAGCGAGGCG |
CATTGACGTC |
AGTAGCCGAA |
CGCTGATTGG |
CTGCGGCCAG |
GCCGTTTCCG |
GTGGAGCTGT |
CGCCTAGCCG |
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481 |
CTATCGCAGA |
GTGGAGCGGG |
GCTGGGAGCA |
AAGCGCTGAG |
GGAGCTCGGT |
ACGCCGCCGC |
CTCGCACCCG |
CAGCCTCGCG |
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561 |
CCCGCCGCCG |
CCCGTCCCCA |
GGTGAGTGGG |
GTCGGCCGGG |
GGCTCAGGCG |
AGGTGAGCTT |
CGTCGCTTCG |
CAGCCGGTTT |
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641 |
GCGGGAGCTG |
GACCGATCCA |
AGATGGCGTC |
ACGGGGAGCG |
ACCTGCAGGG |
GGACGGCCGC |
ACCCCCTGCC |
CCTCCCCGGC |
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721 |
CCGGCGGGCG |
CCTCCCCGCA |
GGCCTCACGC |
CCCCGGCTCC |
GAGTCTGCAT |
CCTCAAGGCC |
GTCTGGGCGT |
TGGCTTTGGT |
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801 |
GCGGGGCTCC |
CCAGCCGCCC |
CGCTCGCGCT |
CGCTGCCCCC |
ACCCCACGGC |
TCCTGGGGCC |
CTGGGCCCTC |
CGCGGCCCTC |
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881 |
CCCGGCCGCC |
TTCGCCCCCG |
CGCGCCGCGG |
CCTCTTCGCT |
CACCCTCCCC |
CATTTCCTGA |
AGGACAACGG |
CTCTATTTTA |
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961 |
CTGGGGTCCG |
CCATCGTCTC |
GTCCGCCGGT |
CCTGGCTCTT |
CTTGTAAGCC |
GGTAGTTTTC |
CTCTCCACTT |
TTGACGACTC |
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1041 |
GTCATTGCTA |
GCAGTAGCCT |
TTCCTCTTCA |
TAGCGGAGTG |
ATCTTTCCCC |
CAACACGACG |
GTCTTAGTCG |
GGCTCCTGAA |
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1121 |
TTTCCTCTTG |
TCCCCTTTCA |
CCTCTCTCCC |
TTTCCCAATT |
TTGCCCCCCT |
GAGGCCTCCT |
CGCCACCACT |
GTGGCCTTCC |
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1201 |
GACTGGCGTA |
GCTTGAAGTC |
TCGGCTTCCC |
TTCATTTTGT |
GGTCATGACC |
GTGGCCTACG |
TGAAGTGAAG |
GGCATTTTCC |
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1281 |
TGCCCTTCTT |
CTAGAAAATA |
CACGGTACCT |
ATTAACCTCT |
TCAGCTCAGA |
GCCTGTGGTG |
ACGACCGTCC |
TACTCCTTGA |
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1361 |
GAGATTCCCA |
AGAGATCCGT |
CTTTTTAGCA |
GAGCGAGGAA |
AGCAAACACT |
TACTCAAGAT |
GACCCTAGGG |
GAGCCGTAAC |
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1441 |
TTGGCTGGTC |
TAAGGGGGTG |
CGGTCTGAAT |
CAGGAACAGT |
TTCTCAAAGT |
GTTTTTATTT |
ATTTCCCAGA |
ATGTAATCCT |
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1521 |
TTCGAAACAA |
TTTTGTCACA |
ACTGAATTTT |
CAAAAGAATG |
AATCTGAGTG |
TTTTGTTTTA |
CATAGAGACA |
ATGCAGCGAA |
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1601 |
AGTTTTAAAG |
CAGTTAAATA |
ATTGTGTGTG |
GGGAGGGAAG |
GCTAGGTTGT |
TGGGCTTTAC |
AAATAAGTAC |
ACATAGAGAA |
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1681 |
TCCGGGTAAC |
TCGATTAAAA |
ATATTAAGAC |
TGTGAAGTCT |
GGTTATTCAG |
GGATTTACAT |
GGTGACTGCA |
TTAATTTTGG |
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1761 |
TACATTTCTG |
TTCGTATACT |
GTCCTATTAC |
CGGTGGCTAT |
CTTTTTGGTT |
TTCGTAATAC |
ATTAGTTGTT |
TCAAACAAAA |
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1841 |
ACACAGTTTC |
ACTCCTTAGG |
CCCAGTTCTC |
TCATCTCTAC |
CAGCCAAAGA |
CCTGATCTTA |
GAATGATTGA |
TCATTTGAAT |
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1921 |
GTTCTTAAAA |
TATGACAATG |
CTTTGAAGCA |
TGAAAGATCT |
GATTTATGAT |
TGTTCTTGGT |
GGCCTTTAAG |
TATTATTTGA |
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2001 |
AATGCAGACA |
ATTCTACTGA |
AGTGGATCTT |
CAGTTCATAT |
GATTGCCTGA |
CCTGGAGAAG |
TGGCTTGTAT |
AAATCTATCC |
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2081 |
TAAAGTAAAT |
GCGCGTTTTT |
GTTTTTGTTT |
TGCCTGTTTA |
AAGTAGCAGC |
ATGATTATTT |
TTCCATGGCT |
TCTAATTTAT |
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2161 |
GTGCTTGTCT |
TGGAGCCACG |
AACTTTCTAA |
TGGTCTGTTA |
ATTAGTCTAC |
TTGTTGTTGA |
CCTTTATGGT |
GAAAGTTGTC |
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2241 |
AAAACAAAAT |
GAGTAACAGT |
GTAGCACTTT |
AGAATAGCTC |
TTTACTCTGT |
TAATTCTTTC |
TATAAGTTCT |
TTTAAATTTA |
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2321 |
CAGTTTCATC |
TCAATAGTTT |
ACAATGCATT |
ATAATTGGAA |
AAGTCTGATT |
AGTATTGAAT |
TCAGTTGCTG |
AGTGGAGGGG |
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2401 |
ACCACACTCT |
TGTCTTCTAC |
TCTTAAGTGC |
TTAGTAATTA |
GGAGTTGGAA |
GGAAAACAGT |
ATATGACCCT |
GTTGTTAAAT |
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2481 |
TAGTAAACTT |
TTAATTCTAG |
GGTAAGGTTA |
GCTGCTCATC |
ATTATCTCTG |
TTTGCTTTAC |
TTTACATAAA |
GGTACCATAA |
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2561 |
TTCGAATCCT |
CTAAAATCCA |
TTAAATGCAA |
TTTATCCATT |
AAATGTAATC |
CATTAAATGC |
AATTTATCTA |
TTGAATCTTC |
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2641 |
ATGCAAGTTT |
GAAACTTAAG |
TGTTTTAACA |
TTCTCCTGTC |
AAGATGAAGA |
AAATATTTTG |
ACAATTTTCT |
GTCCAAATGT |
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2721 |
TTTACAGTTT |
ATGTGGTAAG |
AATTCTCCCC |
TCCCCCAACT |
AAGGATTTTC |
CTTCTTTTAC |
CACTAGTGTA |
TTATCATTTA |
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2801 |
GGGGTGGAAT |
CTGGCAAACG |
AGTCTGGAAT |
AAAGGTTGCT |
TTTAAAACTC |
ATCTAATTTT |
CTTGTGTGTT |
TTTAAAAATT |
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2881 |
TTGATTATGC |
TAGTAGTTGG |
CTAATCAGAT |
CCTCACTCCA |
GTGGTTTGCT |
CTGTGACGTT |
AGGATACTCC |
CATGGGATAG |
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2961 |
AAGTTACGTA |
TAGGGAATGT |
CAGATATTCT |
TCATTGTGCT |
GACTTGCTTT |
CGCTTACAGT |
TGACTTTTGT |
GCCCTGGTAA |
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3041 |
TTCTGTATCC |
TGTTTACCGT |
TTACCTACTT |
CCCACGTCAT |
CATGATTTCT |
TTTGAGGGAG |
AACTGAATGA |
AATTCCCTTA |
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3121 |
AGGGCCTGAC |
TTCAGCACCC |
GTCTCTGCAG |
AGGTTAGTGG |
CTCATACTTC |
CTCCCAGGAG |
CTGAGGTTAT |
CGACTCTCAC |
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3201 |
TGTTGCCTAC |
AGAGCACAGA |
TCCTGAACTA |
AATGAAACAT |
TTACTTGGAA |
TAATGCTAAT |
TCTGTACATA |
TTTTATTCCC |
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3281 |
TAGTCCCCAC |
TTCCCTGTTT |
AAAAACAAAA |
TCTACTTAGA |
AAAAAATCCC |
TGTGAATCAG |
TTGTCTAATG |
AATTTAGCAA |
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3361 |
GTTAAATGCC |
AGATTGACAT |
TTTGCTTTAT |
AGTTTATACA |
AGCATGTGTG |
TGTTTTTTTC |
TCGCAGAGAA |
CCATGGAGTC |
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3441 |
TGGCAGTACC |
GCCGCCAGTG |
AGGAGGCACG |
CAGCCTTCGA |
GAATGTGAGC |
TCTACGTCCA |
GAAGCATAAC |
ATTCAAGCGC |
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3521 |
TGCTCAAAGA |
TTCTATTGTG |
CAGTTGTGCA |
CTGCTCGACC |
TGAGAGACCC |
ATGGCATTCC |
TCAGGGAATA |
CTTTGAGAGG |
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3601 |
TTGGAGAAGG |
TAAAAATAAA |
TGTGGGGAGA |
TGATGAGGTG |
ATTGTGACAG |
TTGTTACATT |
TAATAACTGG |
AATGTTACTA |
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3681 |
ATTTGTATTT |
TTTGGAAGAA |
AAGGAATCTG |
ACTAAATAAA |
AAGTCTAAAA |
CAATTTCAAA |
TAAGAAATAC |
AGTTAAGGCA |
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3761 |
TTTGTAGTAA |
TTTAAAAATT |
CTTAATTAGT |
AGAATTTATC |
AGAAAAATGA |
ACCTGTATGC |
TAACTGTACT |
TGGCTAATAA |
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3841 |
AGGGTTTCCA |
AACAATTCTT |
TGTAACTTTT |
TAAATTAGTG |
CGTAGAACTA |
TAACAGATAA |
AACTGATCAG |
AACTAGTATA |
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3921 |
GCAGTTCTAT |
GAATAAGAAA |
TTCTATAGTT |
CTTAAAGGCA |
GTTAATGCTC |
CTCCCGTTTT |
GAACAAAGCA |
AGTAAGCGTA |
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4001 |
GTAAATCTTA |
TCCCACTTTT |
AAAACTAGTG |
TAATGAAACA |
TGAATCTAGC |
TTGTGACTGA |
TATATCAGAA |
ATTTTCAATT |
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4081 |
AGATTCGGTC |
TATTTTAGTA |
TAGAGTATAT |
CTGATAAATT |
ACTGTAGAGA |
TATTGATATT |
GATGTTCCTC |
AAAAATTTTA |
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4161 |
CTCCATTTTA |
TTGGTCAGGA |
CTTGTTGCGC |
CTTGAAAAAA |
ATTAATCCAA |
TTTTTATTCT |
TTTTTGCTCT |
TCCTCCTTGC |
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4241 |
TTGTATGTCA |
TTGTGACCTA |
CGTATATGGC |
ATATGTTTTT |
CTAAGCAAAG |
TGATAATTTT |
ACATCAGGGA |
TAATTGAAGC |
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4321 |
AAATGAATGC |
TTCAATTCAT |
CTCCCTCAAG |
AAACGATGAA |
TGAAAAAGTC |
TGGGTTACCA |
AATATTTTGA |
ATAGTTTATG |
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4401 |
TGATTCGCTT |
CTGTAAATCA |
GTGAGAGAAA |
CTTACTGATT |
TTCTTGTGCA |
TGTGGAAGTT |
ATGAGGTGGT |
TCATAATGAT |
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4481 |
TATGAATTAA |
TTGAAATGAA |
TCATATACCA |
AAAGAAATGA |
TTCATATACC |
AAAAGAAATG |
AATCATTTCT |
TTTGGTATAT |
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4561 |
GATTATCTAA |
TTGTATAATA |
GAAATAATTT |
GCTTTATTTT |
CCATTGGTTT |
TTATAGTTTC |
TTATAATCAG |
TATAGTTTAT |
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4641 |
TAGTAAAAGA |
ATCTGTACTA |
AGCTTTAAAA |
AGTATTTGGG |
TAGCTCATTG |
ATCAGGTATT |
TTCTATTTTC |
TTTAAAAACT |
|
4721 |
GATTGTTAAA |
ATTTGTATTT |
AGTACCATGA |
TCAGAATAAT |
TAAAAAAAAA |
ACAAAAACAA |
CTAGTCACTG |
TGAATGTTGC |
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4801 |
TTTGCTGTCT |
TGGAATTATA |
GTAGATATTC |
TGGCTTTCTC |
TTATTTATGC |
AATTTCCAAA |
TCATGGAAGT |
ATTGTAGAGC |
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4881 |
CAGGTCATAG |
ATGTAGCTTG |
TTTTGAAGTC |
AAGTGCATTC |
CTGGAGATCC |
GGTTTTGAAA |
TGGGTCACTG |
TAAGGTGATC |
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4961 |
CCTCTTCTTT |
GGACATCAAT |
AGAAACCATC |
AAATGAGAGG |
ATTAAGTTGG |
TGAGACATTA |
AGTGTGTATC |
TTTTTATAGG |
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5041 |
GAGTGTTGAA |
TGTGTGATGC |
TAGTTTCAAA |
GCTTGTAGTT |
GCCACAGTAC |
TGTTTAAAGA |
CTAACAAAGG |
TGGAAAGCAA |
|
5121 |
TAAATAATTA |
TTAAAATGGT |
TTCTTTGCAG |
ATGGAATTTT |
TAGATTTAAT |
GTGTTTCAGC |
TTCTTTAACT |
TTTAATAATT |
|
5201 |
AAAGTCACAG |
TTCAACATGG |
TTTTTGCTGT |
AATTCAAGGG |
TCTTTGTTCA |
CATGTATACA |
TTCCTTCCAG |
GGTTGAATAT |
|
5281 |
AGATACCTGG |
ACCTTTAAGT |
AATTAGATTT |
TCAACTTGTT |
AGTGGGTCAT |
AGTTCTGTGT |
ATTAGGTGTT |
AATTTGTATG |
|
5361 |
TTAGTCTATT |
AGTCCGTTGT |
CATGCTGCTA |
ATAAAGACAT |
ACCGAGGCTG |
GGTAATTCAT |
AAAGGAAAGA |
GGTTTAATTG |
|
5441 |
ACTCACAATT |
CAGCATGGCT |
GGGGAGGCCT |
CAGGAAACTT |
ACAATCATGG |
CAGAAGGAGA |
AGCAAACCCA |
TCCTCTTCAC |
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5521 |
ATGGCAGCAG |
CAAGGAGAAG |
TACAGAGCAA |
AATGGGAAAA |
GTCCCTTATG |
AAACCGTCAG |
CTATCGTGAG |
GACTCACTCA |
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5601 |
CTATCATGAT |
AACAGCATGA |
GGGTAACCCC |
CCTGCCATGA |
TTAAGTTACC |
TCCCACCAGG |
TCCCTCTCAG |
GGCACATAGG |
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5681 |
GATTATGGGA |
ACTGCAATTC |
AAGATGAGAT |
TTGGGTGTGG |
ACACAGCCAA |
ACCATATCAT |
TCCACCTCTG |
GCCCCTCCCA |
|
5761 |
GATCTCATGT |
TTTCACATTT |
TGAAACACAG |
TCATGCCTTT |
CCAACAGTCC |
CTCAGAGTCT |
TAACTCATTC |
CAGCATTAAC |
|
5841 |
TCAAAAGTTC |
AAGTCCAAAG |
TCTCATCTGA |
GGCAAGGCAA |
GTCCCTTCCA |
CCTATGAGCC |
TGTAAAATCA |
GAAGCAAGTT |
|
5921 |
AGTTACTTCC |
TGGGGTCATT |
GGGTAGATAA |
CACCCATTCC |
AAATGGGAGA |
ACTTGGTCAA |
AACAAGGGGA |
GTATAGACCC |
|
6001 |
CGTGCAAATC |
CGAAATCCAA |
CGAGGCAGTA |
ATTAAATCTT |
AAAGTTGCAA |
AAGGATCTCC |
TTTGACTCCA |
TGTCTCACAT |
|
6081 |
TCAGGGCACA |
CTGATGCAAG |
AGGTGGGCTC |
CCGTGGCCTT |
GGGCAGCTCC |
GCCCCTGTGG |
CTTTGCAGGG |
TACAGCCCCC |
|
6161 |
CTCCTGGCTG |
CTTCCATGGG |
CAGGCATTGA |
GAGTCTGTTG |
CTTTTCCAGG |
TGCATGGTGC |
AATCTGTTGG |
TGGATCTACC |
|
6241 |
ATTCTGGAGT |
CTGGAGGATA |
GTGGCCCTCT |
TCTCGTAGTT |
CCATTAGGCA |
GTGCTGCAGT |
GGGGACTCGG |
TGTGGGGGCT |
|
6321 |
CCAAACGACC |
CCACATTTCC |
CTTCCGCACT |
GCCCTAGCAG |
AGGTTCTCCA |
GGAGGGCCAC |
GCCCCTGCAG |
CAAACTTCTG |
|
6401 |
TCTGGGCATC |
CAGGCATTTC |
TGTACATCTT |
CTGAAATCTA |
GGGGGAGGTT |
CCCAAACCTC |
AGTTCTTGAC |
TTCTGTGCAC |
|
6481 |
CCACAGGCCC |
AGCACCACTT |
GTAAGCCACC |
AGGGCTTGGG |
GCTTGCACTC |
TCTGAAGTAA |
TGGCCAGAGC |
TGTACCTTTT |
|
6561 |
AGCCAAGACT |
GGAGCTGAAG |
CAGCTGGAAC |
GCAGGGTACC |
ATGTCCTGAG |
GCTGCATAGT |
ACAGGAGCCC |
CAGGGCATGG |
|
6641 |
CCTAGGAAAC |
CATTTTCCCC |
TCCTAGGCCT |
CTGGGCCTAT |
GATGGGAGGG |
GCTGTCCTGA |
AGGTCTGTGA |
CATGCCCTGG |
|
6721 |
AGACATTTTC |
CCCATTGTCT |
TGGTGATTAA |
CATTTGGCTC |
CTTGTTACTT |
ATGTGAATTT |
CTGCGGCAGG |
CTTGAATTTC |
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6801 |
TCCCCAGAAA |
ATGGGATTTT |
CTTTTCTATT |
GCTTTGTCAG |
GCTGCAAATT |
TTTCAAGCTC |
TGCTTCCTCT |
TGAATGCTTT |
|
6881 |
CCTGCTTAGA |
AATTTCTTCC |
ACCGGATACC |
CTAAATCATT |
TCTCTCAAGT |
TCAAAGTTCC |
ACAGATTTCT |
AGGGCAGGGC |
|
6961 |
CAAAATACTG |
CCAGTCTCTT |
TGCATAGCGA |
GAGTCACCTT |
TACTCCAGTT |
CTCAAGTTCC |
TCATCTCCAT |
CTGAGACCAC |
|
7041 |
CTTAGCCTGG |
ACTTCATTGT |
CCATATTACT |
ATCAGCATTT |
TGGTCAAAGC |
CGTACAAGAA |
ATCTCTAGGA |
AGTTCCAAAC |
|
7121 |
TTTCCCACAT |
TTTCCTGTCT |
TCTTCTGAGC |
CCTCCAGACT |
GTTCCACCCT |
CTTCCTGTTA |
CCCAGTTCCA |
AAGTTGCTTC |
|
7201 |
TGCATTTTTG |
GGTATCCTTG |
TAACAGCACC |
CCACGCTCTG |
TGTACCATTT |
TACTGTATTA |
GTCTGTTCTC |
ATGCTGCTAA |
|
7281 |
TAAAAGACAT |
ACCCAAGACT |
GGGTAATTTA |
TAAAGGAAAG |
TGGTTTGACT |
CACAGTTCCT |
CATGGCTGGG |
CAGGCCTCGG |
|
7361 |
GAAGCTACAA |
TCATGGCAGA |
AGGGGAAGCA |
AACACATTCT |
TCTTCACATG |
GCAGCAGCAA |
GGAGAAGGGT |
CAAGCAAAAG |
|
7441 |
GGGGAAAAGC |
CCCTCAAAAC |
TGTCAGATGT |
CATGAGAGCT |
CACTATCACC |
AGAACAGCAT |
GGAGGTAACC |
ACCCCTGTGA |
|
7521 |
TTAAATTACC |
TCCCACCAGG |
TCCCTCCCAC |
AATATGTGGG |
GATTATGGGA |
ACTATAATTC |
AAGATGAGAT |
TTGGGTGGGG |
|
7601 |
ACACAGCCAA |
ACCATATCAG |
TCTGAAAATA |
CAGTCATATT |
CTCATCACCT |
TCTTCGTCAT |
TACTGGGGGG |
TTGTGTTTCT |
|
7681 |
GTTACCTTCA |
ACTACTCCAT |
AAGAAATGTA |
CCAAAAACTC |
TTGACAGTTG |
GTCTTTTGAA |
AGCTTCTGCA |
TTTTAATTCA |
|
7761 |
GTCATCTGGA |
ATTTGAGTCT |
TCTTTTACTC |
TTGTATTTAT |
TAGACCCTTA |
GGTAAGAGGA |
ATTAAAATAA |
CAGTGACCTT |
|
7841 |
GTGTCTGCTG |
TGTCAGGTAC |
TGTGTGAAGC |
ACTTTATATA |
CATAAATACT |
CGTTATTTCA |
AATGTACGAG |
GTATGTGATT |
|
7921 |
TTCAGCATTT |
TATAGACATA |
GCAGTAAAAC |
TGAGAGAAAT |
TAAGTAATGT |
GGCTGTGGTT |
ATAGACTGTA |
GTCGTCAGCT |
|
8001 |
TTTGCTGGAG |
CAACATACAA |
CCCCCAAATT |
TCAGTGGTTA |
CTACAACAGA |
CCAGTCATGT |
GCAGTTCTTC |
TGGTATCAGC |
|
8081 |
CTGTCTTATG |
TTCTTGACAC |
CACATATCTT |
GTTCTGGGGC |
TGAGCAGAAG |
GAGCAGCCCT |
ATATAGGGCA |
TGCTGTTCTC |
|
8161 |
AAAGCAGAGG |
GAGGGCAGAA |
GCTCAAGGTG |
GACAGAGCCA |
AACCACACAG |
GCAACCATGG |
TATGGCATGT |
CCACTTACAT |
|
8241 |
TCCATGGCCA |
GAGCAAGTCC |
TGTAGCCAAG |
CCTTAAGTCA |
GTGGGGTGGG |
AAGTATACTT |
TACCCACAGG |
GAAGAGTGAC |
|
8321 |
AGAAGCAGGG |
AGGGAACAAA |
TAATCGGGAA |
AACATAGTAG |
TGGGGACAGA |
ATTTGAACCT |
AAGAGTCAAG |
AAGATAGTGC |
|
8401 |
AGAATTTAAT |
GCAAAACCGA |
ATGCAGAATT |
TGAACCTCAG |
AGTCAAGAAC |
ATAATTAACC |
ACTGAGTAGA |
CTGGGAGGTT |
|
8481 |
TTTTCTAATT |
TTTAATTTTT |
TATTGATATA |
TAACATTTGT |
ATGTTTTTAT |
GGAGTACATG |
TGATATTTTA |
CAGGCATAGA |
|
8561 |
ATGTGTAATG |
ATCACGTCAA |
GGTATTTAGG |
TTATTCATCA |
CCTCACTTAA |
AGAGCTGAGG |
AGGAAGGAGA |
CTGACAGAAG |
|
8641 |
GATGACAACA |
GCAAGAGAAA |
GGATATAAAA |
ATATATCATA |
GTATATACTA |
GAAAACTCAT |
GATCTGAGTA |
ATGGCTCTGA |
|
8721 |
GTTGTCAGAT |
TAGGTTATAT |
TCAGATTGCT |
GTTTTTAAAA |
GACTCACTAG |
AATCCATGAG |
ACACTGCTAA |
AATCAGAATG |
|
8801 |
CTTTTGTTAC |
TTCAAAATTA |
ATCTTAAAAA |
TTCAGTGAAG |
TAGAATGTAG |
TCCCAAGTGA |
AATGTTATTT |
GTGAAATTTT |
|
8881 |
TCCTGAAATT |
TTTGTGAAAT |
GTCAGTGACA |
AATTTGGGGG |
TGGGAGAATT |
TGTGTTTTCA |
TTTATACTCT |
TAAACTGTGT |
|
8961 |
GTGTGTTTTA |
TTTTATTTTT |
ATTATTATTT |
TTTTGAGACA |
GTCTTGCTCT |
GTCACCCAGG |
CTGGACTGCA |
GTGGTGCAAT |
|
9041 |
CTCGGCTCAC |
TGCAACCTCT |
GCCTCCTGGG |
TTCAGGCGAT |
TCTCCTGCCT |
CTGCCTCCTG |
AGTAGCTGGG |
GCTACAGGTG |
|
9121 |
CCTGCCACCA |
CACCTGGCTA |
ATTTTTGTAT |
TTTTAGTAGA |
GATGGGGTTT |
CACCATAATG |
GCCAGTCTGG |
TCTTGAACTC |
|
9201 |
CTGACCTTGT |
GGTCTGCCCA |
CCTTGGCCTC |
CCGAAGTGTT |
GGGATTACAG |
GTGTGAGCCA |
CCATGCCTGG |
CCTATTTTTT |
|
9281 |
GAGACAGGAT |
CTCACTCTGT |
TGCCCAGGCC |
TGAGTGCAGT |
GGTGCGATCA |
TGGCTCACTG |
CAGTCTCTAC |
CTTCCAGGCT |
|
9361 |
CAGGTGATCC |
TCCTGCCTCA |
GCTTCCCAAG |
TAGCTGGGAC |
TACAGGTGTG |
TGCCACCACG |
CCCAACTAAT |
TTTTATGTGT |
|
9441 |
TTTTGTAGAG |
ATGAGGTTTT |
ACAATGTTGC |
CTAGGCGGGT |
CTCGAACTCC |
TGGACTCAAG |
TGATCTGCCA |
CCTTCGGCCT |
|
9521 |
CCCAAAGGGT |
TGTGATTATA |
GGCGTAAGCC |
ACTGTACCCA |
GTCATGTATT |
CTTAAACTTT |
AAACTTGGGA |
GAGACTTGAG |
|
9601 |
TTTTATACCT |
GTGTTAATAT |
GAAATGAGAA |
AACCTTACTG |
GTTATTGGAA |
CAACCAGAAT |
TAACATGAAA |
TGAGTTTTCT |
|
9681 |
AAAAACCATA |
TTTTAAAAAG |
TAGGTTACAT |
ATTCACATAT |
TTCAAAGTTG |
TGCAGGTACA |
AAGGGGCATA |
ATAATGAAAG |
|
9761 |
GTCTCCCTCC |
CACGCCATTG |
CTTTTCTTGA |
ATGCTGCCAA |
TGTTCTGGAG |
ATTAATATAT |
GGGCACTTAC |
AAATTTATAT |
|
9841 |
ATAGAAAAGA |
AATAACGGGT |
CAAATGAATG |
AGAAAGTAGA |
AGATAACACA |
TTTTTATTTT |
TTCCCTTTTA |
CTTCAGGCAC |
|
9921 |
AACAACTAAT |
TCTTTAGATC |
TGAGAGGAAT |
TTGTTTTTAA |
GGCTCTAGAT |
GTGAAAAAAG |
GAATGTTTAA |
TAGTTTATCT |
|
10001 |
TAGGTTTTAT |
TTGAATTGGT |
CCAATAAGTA |
GTTTTTAAAA |
GCAAGTAAAC |
TCTTTTTGTC |
TTTTAACTTC |
AAGTTTAAAC |
|
10081 |
CTTGATTACA |
AAGAGTGATC |
CTAGCTCTGC |
TGGGAGAAGT |
ATTATAGATA |
CGATCTCGTT |
TAAATTCGTG |
GTTACCATCA |
|
10161 |
CATCATTTCA |
TTATTTGTTT |
TTATCTGGGA |
TCAAACTGGA |
ATGTGAATTC |
CACAGGCTCA |
GGACCCTCTC |
CTATTTGTTT |
|
10241 |
TTAATTTCCT |
GTTGCCTAGC |
ATAGGTCTTG |
GCCTGGCAGA |
TCCAGAAAAT |
GGCTTATTGA |
GTTAATGAAA |
TAACTCAGTA |
|
10321 |
ATCTAGACAT |
TCTTGGATCA |
CTATGTTGGG |
CTTGAATTGT |
TTTTCCTGAT |
AACATTTCTT |
TTGGCAGGAG |
GGTCTCTTGC |
|
10401 |
TATCTGCAGT |
AGCATCCAAA |
AAAACCCAAT |
TTTCAGGATT |
TTGTCTTGCA |
GTGTGTTACT |
GTTGTGTGCA |
TCACAGATAA |
|
10481 |
TTGTTGTCAA |
GACATTAATG |
AATATCTGAT |
TTGTTACTCA |
CATGTTATGT |
GAGTACTAAT |
GGCTTGTACT |
AATGACTTTT |
|
10561 |
GCCCATTAAT |
AAAGGATAGC |
ATCTGTTATC |
ATCTGAGGTA |
CATTCTGTTG |
AGAGTGTTTC |
AAGTGTTACT |
CTCTTTTTTT |
|
10641 |
CCCCTTTGGA |
ATTGGTGTTT |
TCCTCTTAAC |
TTACATTGTT |
AATGGAAGAA |
GAGATTGGAA |
GTGACTGAGA |
TAGACTATCA |
|
10721 |
TTGGAACATG |
AGAGTGCCAG |
CTTTACATGC |
CGAAGGATCT |
CATTTTGCAA |
ACTCGTAATT |
TCTTTCAGGA |
GGAGGCAAAA |
|
10801 |
CAGATTCAGA |
ATCTGCAGAA |
AGCAGGCACT |
CGTACAGACT |
CAAGGGAGGA |
TGAGATTTCT |
CCTCCTCCAC |
CCAACCCAGT |
|
10881 |
GGTTAAAGGT |
AGGAGGCGAC |
GAGGTGCTAT |
CAGCGCTGAG |
GTCTACACGG |
AGGAAGATGC |
GGCATCCTAT |
GTTAGAAAGG |
|
10961 |
TAGTTTTGAT |
ATTTGAATAT |
CGGGGGGATG |
CTTTTGGGAC |
CCACTTGGTG |
GTCATCTAGT |
CTCCTTTGAT |
GAATGAATCA |
|
11041 |
TAAAATACAA |
AACAGGGTGG |
AACTTCATCC |
ATCCTGTACA |
ATTCTTGGGT |
ACTGGAAAAC |
AGGTTTCTGT |
AATAGCATGC |
|
11121 |
TGTCAGAGGA |
AATAACTAAT |
AGTGATTATG |
AACTAGTGAA |
TAATTGCATT |
TTGGGGTTTG |
TTATTTCCTT |
GCAGTTGTTT |
|
11201 |
TGCAGTAGAA |
GGAGGTGGGC |
GGTATTGCTT |
TTTCTCTTGA |
ATCGTGATGT |
CCTTTTTTTG |
CTATCCTATT |
AAATGTTGTG |
|
11281 |
GCTTTTAACC |
TTTTATTCTA |
CGAGCCTCAT |
TTGTCCTGTG |
TTCTCCTCTT |
CCTCAGAGCC |
AGGCTATTTT |
GAGTTATGCT |
|
11361 |
GTTAGCCTTA |
AAGGGGAACA |
GAATTGTCCT |
GGCACTTGAG |
GCTTGTGAAG |
CTAACAGATC |
ACAGATTTTT |
AAAATGACTA |
|
11441 |
ATTATTATAA |
AATACTTAGT |
TTTGCCTCAG |
AATAATGACC |
TTGGTCCAGG |
TGTTTTGATT |
TGTTTCTTTA |
GTTGTTAACT |
|
11521 |
GGGAACCAAG |
TACCAGACTT |
TATATTTAGG |
CCTGGCTGTA |
GGCAAGGGGA |
TTAATTAGTC |
AATACTTGTT |
GAGTAGTTTA |
|
11601 |
TGGATCAAAG |
ATAGTACAAG |
TGTGTTGTAG |
TGAAACACTA |
CAAAGCAGTC |
TTGTTTAAAT |
ACCATAATGT |
GGCTTGACAT |
|
11681 |
TTAATTGAAG |
CGCAGGTTGC |
AAACGTGAAA |
TGTTTTTGGT |
TTATGGAATT |
GTCATTTGAC |
CTTCAGTTCT |
TTTCTAGGTT |
|
11761 |
ATACCAAAAG |
ATTACAAGAC |
AATGGCCGCT |
TTAGCCAAAG |
CCATTGAAAA |
GAATGTGCTG |
TTTTCACATC |
TTGATGATAA |
|
11841 |
TGAGAGAAGG |
TAGGAACAGG |
CTCTTTCTTA |
ACACTATTTT |
TCAAGTAAGG |
GTGTGATCCC |
AAATTGTTTT |
CAACACTTGT |
|
11921 |
TGCAAGTTTT |
AGAGCTCTTA |
GTAATTGTTC |
ACCAGATGAC |
AGTCTGGGGT |
CTTTAATTCT |
AAGCTTAATG |
TTTGAAATTC |
|
12001 |
ACGGAAGAGA |
CATGTGAAAT |
GTAACACGAG |
GCCTTCTCTC |
TTTTGCAGTG |
ATATTTTTGA |
TGCCATGTTT |
TCGGTCTCCT |
|
12081 |
TTATCGCAGG |
AGAGACTGTG |
ATTCAGCAAG |
GTAAGGGCCT |
CTGGAGCATG |
CAATATTGTT |
ACGGGAGAGG |
AGGCGAGACT |
|
12161 |
AGAGGATTTT |
TTTGGTTTTG |
TTTTATTGAA |
GTTTGTTTTC |
CTCTTTGATC |
CTACCACTTT |
TTTTTTTCTG |
TTATACTATT |
|
12241 |
GGATTTTTCT |
ATTTCTTTTA |
AATTAAGATT |
TTCTGAGATG |
GACAGAACAC |
TTTGTATTGG |
GAACTAATAT |
TTTTGATACA |
|
12321 |
GTTTTGTTTA |
TAATTTAAAG |
GAAATGCCTA |
CATTGTCTTA |
CCTTGAATGT |
CATATAGAAT |
TGCAGAATCA |
TATATATCTC |
|
12401 |
TCATGTTCTT |
TATATTGTTA |
ATCACTTTTA |
AAGTAAGAAA |
TAAATGAAAC |
ACCTACATTC |
TTCATTGTAT |
AGCCCTGTCT |
|
12481 |
ATTAAAAAGG |
TTCTAGGACT |
TCTATAGATT |
CTTACTTTGC |
CTATATAGAC |
TAACATGGAT |
CTAACTTTTT |
GACTATCTTC |
|
12561 |
CTCTTTTTAT |
TTTCTTATTT |
ATTCTTGACA |
TTTTATGAGT |
GGGTATATAT |
TTTCATTTTG |
TGGCAGCCTG |
ATAATTTGTT |
|
12641 |
ATTAACTATT |
TGAGTTGTTT |
CTAATGTCCT |
TGTTATAAAT |
GCCATAGCAG |
TTAATAACTA |
CACATATGTA |
GCTTTTAAAA |
|
12721 |
ATTTTTTTCA |
GAGGTATTCT |
TCACCATGAG |
ATGACTAAAA |
AAATTTTGAT |
TAATTCTATG |
ACTTTTAAAA |
TATGTTGCTT |
|
12801 |
GATTTTCTTT |
CCCCTGAAAG |
ATTGTGTTAG |
TTTGTAACAC |
ACTCTCACAG |
TACCACTGTA |
AAATAAGTTT |
ATTGTTTTGT |
|
12881 |
AATAATTTTG |
ATAATTTCTT |
TCTTTAATTT |
GGAATATGCT |
TCTAACTTTT |
TTACCCTCTT |
TTAGGTGATG |
AAGGGGATAA |
|
12961 |
CTTCTATGTG |
ATTGATCAAG |
GAGAGACGGA |
TGTAAGATTT |
ACCAATATCA |
AAAATATGTT |
GATCTTAAAA |
GCCAATGTAT |
|
13041 |
TGATCGCTTC |
CGAGCAATAA |
GAATAGTGAT |
TTTGAAGGGT |
CATTACATCC |
CTTGTATGTC |
AGATTTTATT |
AATACCTTTT |
|
13121 |
GCCAAGTATT |
TTTATGACAC |
AGAGAAACTC |
TTTAAAGGTA |
ATTTTCTGTT |
CAGAACTTTG |
CTGGAGTGGT |
GGTGAAGAAG |
|
13201 |
TGTGTGTAGC |
TGGGTGCAGT |
GGCCGATGCC |
TATAATCCCA |
GCACTTTGGG |
AGATGGAGGC |
AAGAGGGTTG |
CTTGAGCCCA |
|
13281 |
GGAGTTCAAG |
ACCAGCCTGG |
GCAACAAAGT |
GAAACCTCAT |
CTCTTAAAAA |
AAAAAAAAAA |
AAAAGATTCT |
AGACCCAGCC |
|
13361 |
ATTAGCTAGC |
AAAATTAATA |
TACCTTTCTT |
ATTCACAAAT |
GAAATGGGGA |
CAATAATAGC |
ATTGATCTTT |
TAGGATTATT |
|
13441 |
AGAAGATTCA |
GTGACCTAAT |
GCAAGTAAAA |
TGTTTAGCAT |
AGTGCTCAGC |
ACGGTTCTCT |
AAGTATCTGT |
GACTGGTATT |
|
13521 |
AGTGCTTAGC |
TGACCTTTTT |
CCCTTACATC |
CTTACAGAGT |
GCTTTTTTCT |
TATCAGATAA |
TTAAATCAGG |
TAAATTATAG |
|
13601 |
ACACTCTTAA |
CTCATTTAAC |
TCGTCAGAAA |
TCACCTATTC |
TTCTCTGTTG |
TGTACTGCAA |
ACATAATATA |
TTCTGTTTTT |
|
13681 |
TAAAACAAAG |
TTCAGGATTG |
TGACCTTTTA |
AAAAGGTTTG |
AGGGTTTTTA |
ACATTTAAGT |
GTTTGTATCT |
AGAAAATAAA |
|
13761 |
CTTTTTTGAT |
GTCACTTGCA |
CTTTAGGTCT |
ATGTTAACAA |
TGAATGGGCA |
ACCAGTGTTG |
GGGAAGGAGG |
GAGCTTTGGA |
|
13841 |
GAACTTGCTT |
TGATTTATGG |
AACACCGAGA |
GCAGCCACTG |
TCAAAGCAAA |
GACAAATGTG |
AAATTGTGGG |
GCATCGACCG |
|
13921 |
AGACAGCTAT |
AGAAGAATCC |
TCATGGTAAG |
AGACCATGGT |
GTTTGAGAGT |
GTGATTTAGA |
ATTCTCATCT |
ACGTAACTAA |
|
14001 |
TGTTTGAATA |
TTACCAAATT |
AAAAAGAGAA |
TATTTCTTTT |
AATGAGCAAA |
TATTTCTTTC |
TTTTAATAAG |
CGAATATTTT |
|
14081 |
TCTTTTAATG |
AGCAAATACT |
TTGCATTAAG |
CCCAGCTTAG |
CATTATTCAT |
TATGCCATTT |
TAGGCAGTGA |
TATTTTAGAA |
|
14161 |
CAAAACCTTG |
GGAAACAAGA |
TCTGGTATAT |
ATGTGCTGGT |
CATCTCATGT |
TTGGAAATCT |
ATCCATTTGC |
TGGTAGGCAC |
|
14241 |
ATCTTAATTT |
ACCTAGTTAT |
ACCCATTACA |
GCATGATAGG |
TGCTGCTTTT |
AAGTGCTTAA |
AGTTATTTGG |
GGCCATTCAG |
|
14321 |
AAATAATCAG |
CTTCCCTAAC |
CTGTGAAAGT |
GGGTTATCAG |
TAATGTATAT |
GTATGTCATG |
TCCCCTCTCG |
TTAAAGGAAT |
|
14401 |
AAACAAAATA |
CTAAAACCAT |
TGGAACTTTC |
TGGTGATAGT |
CAGATTTTTT |
GAGAACGTTG |
TGATAAATTT |
ATAGGATAGC |
|
14481 |
TTTGGATGTT |
TAAGTCTCAG |
CCAATGCATT |
GGTCATTTTT |
AATGGTTTTC |
TTAAATTTGT |
GCAGTGTCCA |
TCTGACCATT |
|
14561 |
TGAAAATGTA |
CAGCCTGATG |
TACTTTGAAA |
TTTTTCTGCA |
TTTGGGATAT |
ATAGATAGAT |
TAGATTAGAT |
AGATAGTCTT |
|
14641 |
GTCCTTCGCA |
GCAACATAGA |
TAGAGCTGGA |
GGCCATTTTT |
CTAAGCAAAA |
TAACACAGGA |
ACAGAAAACC |
AAACCACATG |
|
14721 |
TTCTCACTTA |
CAGTTGGGAG |
CTAAGCAATG |
AGAACACGTG |
GATACTAGAA |
GGGGAACAAC |
AAACACTGGG |
GCCTACTTGA |
|
14801 |
GGGTGGAGGG |
TGGGAAGAGG |
GAGAGGATCA |
GGAAAAATAC |
CTGTGGTGTA |
CTTTACTTAT |
TACCTGGGCA |
ACAAAATTAC |
|
14881 |
CTGAACACCA |
AACCCCTGTG |
ACACCCAGTT |
TACCTATATA |
ACCTGCACAT |
GTACCCCTGA |
ACCTTAAACC |
CACACACACA |
|
14961 |
AAAAAACGCT |
TATGGCAAAG |
ATAAGTCTAA |
ATTTTAGAAA |
GATTGGTTTT |
GAAGTGATGT |
GACAGTCTAC |
TGGAGAAGAA |
|
15041 |
ACTGACCATA |
CAGTTAGTTC |
TGCATTTCCT |
CTACAGGAAT |
ACTATTAGTA |
AAAGGAAACA |
TAGAATGTTT |
ACAGCTTTAT |
|
15121 |
CTCATTGTCA |
AAGAAGGAAG |
AGGTAGGACC |
TGGAACTATT |
GGTTTGAAAT |
AAAATATTTT |
ACTTTCTCAT |
AGTGGGCCTG |
|
15201 |
AAAGGAAATT |
AGGGCCTCAC |
AATGCTTTGG |
CTTTGTGGAC |
AGGAATTAGG |
AACTGTAGAT |
ATGGGGTGAA |
ATATCTATAT |
|
15281 |
AGCTGGGTAG |
GGGAGGATAT |
GGTCCTTTTT |
TTATAGAATA |
AAGACATGTC |
AATTGTATAG |
GTGAGAAGCC |
AGAACTAATG |
|
15361 |
GAGGAATCTG |
CATTTAAATA |
CCAGCGTTGA |
ACAGGAAGAA |
CACTAGGATT |
ATTGGGTTGT |
AAATGACCTA |
GATTACTTTT |
|
15441 |
GTGAGAAAAT |
ATTTTCAGAG |
ATAAATTGGG |
TTGGCAGTGG |
CACAAAATCA |
GTTTGAGAGT |
AAACATGGAA |
ATTGGACATT |
|
15521 |
GGTTTAAAGT |
GTGTGGAAAA |
ATATCTTGAG |
TGATAGGCTC |
AGGTATAAAC |
CGGTATTTCG |
ACTGTATTTG |
GAAGTTGGGA |
|
15601 |
AATGCTTTGT |
GAAATATGTC |
AACATACTGG |
TTGCAAATGC |
TAGGAATTGG |
GCATAATATT |
GGCGGAAAAT |
AAAAATCACA |
|
15681 |
AGAATGTCAT |
ATCATTCATT |
ACCTGTAAAA |
TAAAAATGAA |
TTAGTTAAAA |
TTAAACTTTC |
CTCATTAAAA |
GCAACAAGCT |
|
15761 |
TTGACTTTCT |
GGTTTTAAAA |
TTTATTTGAA |
ACTTAATATT |
TATTATTCCA |
TAGCATTATG |
TGGTGATAAT |
TACACGTCTT |
|
15841 |
GGGGATATCA |
CTTTTGTTAT |
TTTTATTTTT |
AGGGAAGCAC |
ACTGAGAAAG |
CGGAAGATGT |
ATGAGGAATT |
CCTTAGTAAA |
|
15921 |
GTCTCTATTT |
TAGGTGAGTT |
GTAAAGTGTG |
TTAACTTTGC |
TAGTATGTGA |
GATACCCCTG |
AATTAGAATT |
GGATGGACTT |
|
16001 |
GGGAAAAGCC |
TTCTGAAAGT |
ATAATTGCTA |
CTCATTCCCC |
CTGAAAAGAC |
AGAAGGGCTG |
AAAGTCCTTC |
TGACTGTGGA |
|
16081 |
CATTCACAGT |
TATTTCCTCT |
GTGACTTCCC |
GTCTCTCTTG |
TTCCATCATT |
GAGTTGATTG |
GTTCAGAAAA |
GTGAGTACTT |
|
16161 |
CCAACAATAC |
ATTTCCTCTG |
TGGAAAGATT |
AGGTATCATT |
TGCTGGCATC |
CTCTGAAAAC |
ATGCCAGAAG |
TTTGTTGAAA |
|
16241 |
TTTAGAGTAA |
AGCAGATTAA |
TTGAAGATAT |
TCTTTTGTGC |
ATTTTGTTAT |
GTGGACTTGG |
AGATGTTAGA |
ACTTGTTCTT |
|
16321 |
CATGAAAGGG |
GAATGGGGAT |
TTTTATAAGG |
TAACAGGCTT |
CTGCCATTGT |
TTATTACAGT |
GAATTTTTCA |
CCTCTTCTTT |
|
16401 |
GTCTTTTCTT |
TGAATTGGTT |
ACATATGCTT |
TGTGTTTTGG |
ATAGTAGTTT |
GGCCTTTGGG |
AATAAAAGTT |
ATTTTCTAGT |
|
16481 |
TCTTTTTCAT |
AAAGTAAACC |
AAGAATTTAA |
ATAGATTAAA |
TTATTTCTAT |
GAAACTTTGG |
AACGATATGG |
ATGGGGAAAC |
|
16561 |
TATGACTTTT |
GAGTATTGTA |
GTTGTAGGTT |
TGATTTGCAT |
TGATGGCAAT |
CTTCAGGAAT |
ACTTAAGGAT |
TACATTTTCT |
|
16641 |
TATTCCCTTG |
CCATTTGGTA |
CAGTTGGTAT |
AAATTAACCT |
AGCCACTGGG |
CTACCGAAGT |
AAGGATCTAA |
GGGCTATCTG |
|
16721 |
CAGGCAGTAT |
GAGAATCCTG |
CTCAGACTAG |
AGGTAATTGA |
AGACAGGTAC |
CACTTTTAAT |
CTGAGACACT |
ACTAGAATGT |
|
16801 |
TGAATGGGCA |
TGGCTATTTG |
GTTGAATCTC |
TTTATACTTT |
CTTTTTACCT |
TTATAACAGC |
ACCAAATAAT |
ACAGAGCAGT |
|
16881 |
TATTTTGATT |
CTTGTCTTTC |
AGAGTCTCTG |
GACAAGTGGG |
AACGTCTTAC |
GGTAGCTGAT |
GCATTGGAAC |
CAGTGCAGTT |
|
16961 |
TGAAGATGGG |
CAGAAGATTG |
TGGTGCAGGG |
AGAACCAGGG |
GATGAGTTCT |
TCATTATTTT |
AGAGGTAAAG |
AACTCAGAAT |
|
17041 |
TTAATACTTG |
AATTTTAGAG |
GTAAAGAACT |
CAGAATTTAA |
TACTTTAAAA |
AGTTGTACGC |
TCTAAGAGGG |
AAAGAGTGGG |
|
17121 |
CTAATTCTGA |
ACTATAGCTT |
TAGTTTTTAA |
GAATACCTGA |
CCATTTTATT |
TTAAAATTAT |
CTTTTACTTT |
GAAATGCTGT |
|
17201 |
TGTTTGGTTT |
TCTGCCAGGT |
CACTATATTT |
TTAAATGAGT |
TTGAGTCAGA |
ATTCTTGAAG |
GGCCCTAGAC |
ATGAAAAGCC |
|
17281 |
AAATTCTAAA |
AACCATTTAA |
CATAACAAAC |
TGTGATGATT |
CTGCACTATT |
CTTGTTAAAA |
TGCAAGTGTT |
TGGGCTATTT |
|
17361 |
GGCAAATAAG |
GATTAAAGGT |
AATTATTTAA |
ATTTGAAAAA |
TTACTGTGTT |
TGTATATCTC |
CACATTCCAT |
GGAAATGTAT |
|
17441 |
AGCAGATACT |
CTTGCTAAGC |
GGATCCAAGT |
GGCAGATTTC |
TATGAATGTG |
GCTCCATAGT |
TGCTAATTGA |
TTTTATTTAA |
|
17521 |
ATCAGGGGTC |
AGGAGACTGT |
AAAGGGCCAG |
GTGGTAAGTA |
AGTTAAGCTT |
TGTGGACCAT |
AGGGTTTCAT |
TCGCAAAGTC |
|
17601 |
TCAACTCTTG |
TCATAGTGCA |
AAAGCAGCCA |
CAAATAATAT |
GTAAATGAAT |
GTATGTGGTA |
TTTCAGTAAA |
GTTTGATTTG |
|
17681 |
CGAAAGAGAC |
AGTGAGCTTG |
GATTTAGCCC |
TTCATCTACA |
GTTTGCTAAC |
CCAAGTGTGC |
ACCCTTTAAG |
CACCTTAGCT |
|
17761 |
TGATACGAAG |
AACCTCGCTA |
GCAGGAGATG |
CTGGTAAAAT |
AGAAATTGAA |
GCTCATGTGG |
TGACTAACTT |
TAAAGTCATT |
|
17841 |
TTTTATCATA |
TGCACACATT |
TGCAAGGTAG |
TTAAAATTGC |
ATAGGATGTT |
TAAGGTGCCA |
CCCTGGGTTT |
GAGAGTGTGT |
|
17921 |
GTTTGTTTAG |
CTTTTTGGTG |
ATTTTATTAT |
AGGGGTCAGC |
TGCTGTGCTA |
CAACGTCGGT |
CAGAAAATGA |
AGAGTTTGTT |
|
18001 |
GAAGTGGGAA |
GATTGGGGCC |
TTCTGATTAT |
TTTGGTATGT |
ATGAATTCCC |
TCACAATAAA |
TACATGGTTT |
CTTTAAGTCA |
|
18081 |
CCTCTCAGTG |
AGATATTGTA |
GTCTTCCATA |
ATTTTGTCTT |
CTCCTGAATT |
TTATTTTCTA |
ACTGCAGTCT |
TTTTTGGCTC |
|
18161 |
TGAGAGGGAA |
GGTGTGAGAT |
TTTGATCTTT |
ACTCATTTAA |
TGAAATTACT |
GATTGTCTCA |
TATCTATTGT |
CTTCTTTCTC |
|
18241 |
AGAAGTGCAC |
TGCTTTAAGG |
AAATGTTTTT |
CATAGAAGTT |
AGCCTGTTAC |
CCATCTTTGC |
TTTCTCCAGG |
TGAAATTGCA |
|
18321 |
CTACTGATGA |
ATCGTCCTCG |
TGCTGCCACA |
GTTGTTGCTC |
GTGGCCCCTT |
GAAGTGCGTT |
AAGCTGGACC |
GACCTAGATT |
|
18401 |
TGAACGTGTT |
CTTGGCCCAT |
GCTCAGACAT |
CCTCAAACGA |
AACATCCAGC |
AGTACAACAG |
TTTTGTGTCA |
CTGTCTGTCT |
|
18481 |
GAAATCTGCC |
TCCTGTGCCT |
CCCTTTTCTC |
CTCTCCCCAA |
TCCATGCTTC |
ACTCATGCAA |
ACTGCTTTAT |
TTTCCCTACT |
|
18561 |
TGCAGCGCCA |
AGTGGCCACT |
GGCATCGCAG |
CTTCCTGTCT |
GTTTATATAT |
TGAAAGTTGC |
TTTTATTGCA |
CCATTTTCAA |
|
18641 |
TTTGGAGCAT |
TAACTAAATG |
CTCATACACA |
GTTAAATAAA |
TAGAAAGAGT |
TCTATGGAGA |
CTTTGCTGTT |
ACTGCTTCTC |
|
18721 |
TTTGTGCAGT |
GTTAGTATTC |
ACCCTGGGCA |
GTGAGTGCCA |
TGCTTTTTGG |
TGAGGGCAGA |
TCCCAGCACC |
TATTGAATTA |
|
18801 |
CCATAGAGTA |
ATGATGTAAC |
AGTGCAAGAT |
TTTTTTTTTA |
AGTGACATAA |
TTGTCCAGTT |
ATAAGCGTAT |
TTAGACTGTG |
|
18881 |
GCCATATATG |
CTGTATTTCT |
TTGTAGAATA |
AATGGTTTCT |
CATTAAACTC |
TAAAGATTAG |
GGAAAATGGA |
TATAGAAAAT |
|
18961 |
CTTAGTATAG |
TAGAAAGACA |
TCTGCCTGTA |
ATTAAACTAG |
TTTAAGGGTG |
GAAAAATGCC |
CATTTTTGCT |
AATTATCAAT |
|
19041 |
GGGATATGAT |
TGGTTCAGTT |
TTTTTTTTTC |
CAGAGTTGTT |
GTTTGCCAAG |
CTAATCTGCC |
TGGTTTTATT |
TATATCTTGT |
|
19121 |
TATTAATGTT |
TCTTCTCCAA |
TTCTGAAATA |
CTTTTGAGTA |
TGGCTATCTA |
TACCTGCCTT |
TTAAGTTTGA |
AACTAACTCA |
|
19201 |
TAGATTGCAA |
ATATTGGTTA |
GTATTTAACT |
ACATCTGCCT |
CGGCTCACAA |
ATTCCGATTA |
GACCTTTATC |
CAGCTAGTGC |
|
19281 |
CAAATAATTG |
ATCAGATGCT |
GAATTGAGAA |
TAAGAATTTG |
AGGTCTACAT |
TCTTGGTTGT |
TAATTTAGAG |
CGTTTGGTTA |
|
19361 |
AAGTATGTCC |
TTCAGCTGAC |
TCCAGTATAA |
TCTCCTCTGC |
TCATTAAACT |
GATTCCAGGA |
GATTGGATTT |
GCTGTGACTA |
|
19441 |
GATACAGATG |
GAGCAAATGT |
CCTAACAGAG |
AAATAGAGGT |
GATGCTGCTA |
AAGGGAGAAA |
TGCCAGGCGG |
ACAAAGTTCA |
|
19521 |
GTGTCGGGAA |
TTTTCCCCGT |
GACATTCACT |
GGGGCATGAG |
ATTTTGGAAG |
AAGTTTTTTA |
CTTTGGTTTA |
GTCTTTTTTT |
|
19601 |
CCTTCCTTTT |
TATTCAGCTA |
GAATTTCTGG |
TGGGTTGATG |
GTAGGGTATA |
ATGTGTCTGT |
GTTGCTTCAA |
ATTGGTCTGA |
|
19681 |
AAGGCTATCC |
TGCTGAAAGT |
CCTGCTTTCC |
TATCTAGCAT |
TTATTTCTCT |
GGCAAACTTT |
TCTTTCTTTT |
CTTTTTTAAA |
|
19761 |
GTAAACTTGT |
GTATTGAGTC |
TTAACTGTAT |
TTCAGTATTT |
TCCAGCCTTA |
TGTGTTACAT |
TATTCCAATG |
ATACCCAACA |
|
19841 |
GTTTATTTTT |
ATTATTTTTT |
TAAACAAAAT |
TTCACAGTTC |
TGTAATGTAG |
GCACTTTTAT |
TTTCATTGTG |
ATTTATATAT |
|
19921 |
AAGGTAATGT |
AGGGTTATAT |
TTGGGAGTGA |
CTGCAAGCAT |
TTTTCCATCT |
GTGTGCAACT |
AACTGACTCT |
GTTATTGATC |
|
20001 |
CCTTCTCCTG |
CCCTTTCCCA |
GGTAATTTAA |
ATTGGTCATG |
GTAGATTTTT |
TTCATAGATT |
TGAAAAACTT |
TTAGGTTGTT |
|
20081 |
ACCAAGTATG |
AAGTATAAAT |
CTGGGGAAGA |
GGTTTTATTT |
ACATTTTAGG |
GTGGGTAAGA |
AAGCCACCTT |
GTTACAAATT |
|
20161 |
TTTTAATTTC |
CAAAATAATC |
TATATTAAAT |
GAGGGTTTCT |
GATCTGTACT |
TTGTGTTTAG |
CTACCTTTTT |
ATATTTAAAA |
|
20241 |
AATTAAAAAT |
GAAAATTACG |
TTCTTACAAG |
CTTAAAGCTT |
GATTTGATCT |
TTGTTTAAAT |
GCCAAAATGT |
ACTTAAATGA |
|
20321 |
GTTACTTAGA |
ATGCCATAAA |
ATTGCAGTTT |
CATGTATGTA |
TATAATCATG |
CTCATGTATA |
TTTAGTTACG |
TATAATGCTT |
|
20401 |
TCTGAGTGAG |
TTTTACTCTT |
AAATCATTTG |
GTTAAATCAT |
TTGGCTTGCT |
GTTTACTCCC |
TTCTGTAGTT |
TTTAATTAAA |
|
20481 |
AACTTTAAAG |
ATAAGTCTAC |
ATTAAACAAT |
GATCACATCT |
AAAGCTTTAT |
CTTTGTGTAA |
TCTAAGTATA |
TGTGAGAAAT |
|
20561 |
CAGAATTGGC |
ATAATTTGTC |
TTAGTTGATA |
TTCAAGGCTT |
TAAAAGTCAT |
TATTCCTGGG |
CTTGGTAAGT |
GAATTTATGA |
|
20641 |
GATTTACTGC |
TCTAGAAAGT |
ATAGATGGCC |
AAAGGACCGT |
TTTGTATTGC |
TTCCTGATTA |
CCAGTCTGAT |
TATACCATGT |
|
20721 |
GTGCTAATAT |
ACTTTTTTTG |
TTATAGATTG |
TCTTAATGGT |
AGGTCAAGTA |
ATAAAAAGAG |
ATGAAATAAT |
TTAAATTCTT |
|
20801 |
AA |
|
|
|
|
|
|
|
|
|
|
|
|
>ref|Gene_ID:5573|PRKAR1A|NC_000017.10:66508109...66528910 (+)
CAGGGAGGGGGTGGAAAGGAGGGAGAAAAGGCAGAGGCGTCAAGGGAGGCCGGAGGGAGAGTGGGGTGGACAGAGGAGCG
GAGGGACGAGAGGGAAGCGCACGATAGCTGCGCGGAGAGAGAGCGAAGAGCAGGCGGAGGAACAAAGGCGACCCAAGACA
CCCAGAGAGGGACAGGTAAGGAGGGGCAGGTGAGCAGGAAGGAGGAGAGAACCGGGCTAGGGAGACTGCGGAAAGGAGAA
GTGGCGGGCGTGAGGAAACTGCTGTGGATAAGGGACGAGTAAGATGGAAAGAATGGCGGAAGACGAACGACCGCAGAGTG
AGGGTCCTTCCAAGAGCGACCAGGGGGGAGGAACTGGGGCTGTTGCGCCCTTAAGGTTGCTAAGGCGACGGTTCTGGCCA
GAGCGAGGCGCATTGACGTCAGTAGCCGAACGCTGATTGGCTGCGGCCAGGCCGTTTCCGGTGGAGCTGTCGCCTAGCCG
CTATCGCAGAGTGGAGCGGGGCTGGGAGCAAAGCGCTGAGGGAGCTCGGTACGCCGCCGCCTCGCACCCGCAGCCTCGCG
CCCGCCGCCGCCCGTCCCCAGGTGAGTGGGGTCGGCCGGGGGCTCAGGCGAGGTGAGCTTCGTCGCTTCGCAGCCGGTTT
GCGGGAGCTGGACCGATCCAAGATGGCGTCACGGGGAGCGACCTGCAGGGGGACGGCCGCACCCCCTGCCCCTCCCCGGC
CCGGCGGGCGCCTCCCCGCAGGCCTCACGCCCCCGGCTCCGAGTCTGCATCCTCAAGGCCGTCTGGGCGTTGGCTTTGGT
GCGGGGCTCCCCAGCCGCCCCGCTCGCGCTCGCTGCCCCCACCCCACGGCTCCTGGGGCCCTGGGCCCTCCGCGGCCCTC
CCCGGCCGCCTTCGCCCCCGCGCGCCGCGGCCTCTTCGCTCACCCTCCCCCATTTCCTGAAGGACAACGGCTCTATTTTA
CTGGGGTCCGCCATCGTCTCGTCCGCCGGTCCTGGCTCTTCTTGTAAGCCGGTAGTTTTCCTCTCCACTTTTGACGACTC
GTCATTGCTAGCAGTAGCCTTTCCTCTTCATAGCGGAGTGATCTTTCCCCCAACACGACGGTCTTAGTCGGGCTCCTGAA
TTTCCTCTTGTCCCCTTTCACCTCTCTCCCTTTCCCAATTTTGCCCCCCTGAGGCCTCCTCGCCACCACTGTGGCCTTCC
GACTGGCGTAGCTTGAAGTCTCGGCTTCCCTTCATTTTGTGGTCATGACCGTGGCCTACGTGAAGTGAAGGGCATTTTCC
TGCCCTTCTTCTAGAAAATACACGGTACCTATTAACCTCTTCAGCTCAGAGCCTGTGGTGACGACCGTCCTACTCCTTGA
GAGATTCCCAAGAGATCCGTCTTTTTAGCAGAGCGAGGAAAGCAAACACTTACTCAAGATGACCCTAGGGGAGCCGTAAC
TTGGCTGGTCTAAGGGGGTGCGGTCTGAATCAGGAACAGTTTCTCAAAGTGTTTTTATTTATTTCCCAGAATGTAATCCT
TTCGAAACAATTTTGTCACAACTGAATTTTCAAAAGAATGAATCTGAGTGTTTTGTTTTACATAGAGACAATGCAGCGAA
AGTTTTAAAGCAGTTAAATAATTGTGTGTGGGGAGGGAAGGCTAGGTTGTTGGGCTTTACAAATAAGTACACATAGAGAA
TCCGGGTAACTCGATTAAAAATATTAAGACTGTGAAGTCTGGTTATTCAGGGATTTACATGGTGACTGCATTAATTTTGG
TACATTTCTGTTCGTATACTGTCCTATTACCGGTGGCTATCTTTTTGGTTTTCGTAATACATTAGTTGTTTCAAACAAAA
ACACAGTTTCACTCCTTAGGCCCAGTTCTCTCATCTCTACCAGCCAAAGACCTGATCTTAGAATGATTGATCATTTGAAT
GTTCTTAAAATATGACAATGCTTTGAAGCATGAAAGATCTGATTTATGATTGTTCTTGGTGGCCTTTAAGTATTATTTGA
AATGCAGACAATTCTACTGAAGTGGATCTTCAGTTCATATGATTGCCTGACCTGGAGAAGTGGCTTGTATAAATCTATCC
TAAAGTAAATGCGCGTTTTTGTTTTTGTTTTGCCTGTTTAAAGTAGCAGCATGATTATTTTTCCATGGCTTCTAATTTAT
GTGCTTGTCTTGGAGCCACGAACTTTCTAATGGTCTGTTAATTAGTCTACTTGTTGTTGACCTTTATGGTGAAAGTTGTC
AAAACAAAATGAGTAACAGTGTAGCACTTTAGAATAGCTCTTTACTCTGTTAATTCTTTCTATAAGTTCTTTTAAATTTA
CAGTTTCATCTCAATAGTTTACAATGCATTATAATTGGAAAAGTCTGATTAGTATTGAATTCAGTTGCTGAGTGGAGGGG
ACCACACTCTTGTCTTCTACTCTTAAGTGCTTAGTAATTAGGAGTTGGAAGGAAAACAGTATATGACCCTGTTGTTAAAT
TAGTAAACTTTTAATTCTAGGGTAAGGTTAGCTGCTCATCATTATCTCTGTTTGCTTTACTTTACATAAAGGTACCATAA
TTCGAATCCTCTAAAATCCATTAAATGCAATTTATCCATTAAATGTAATCCATTAAATGCAATTTATCTATTGAATCTTC
ATGCAAGTTTGAAACTTAAGTGTTTTAACATTCTCCTGTCAAGATGAAGAAAATATTTTGACAATTTTCTGTCCAAATGT
TTTACAGTTTATGTGGTAAGAATTCTCCCCTCCCCCAACTAAGGATTTTCCTTCTTTTACCACTAGTGTATTATCATTTA
GGGGTGGAATCTGGCAAACGAGTCTGGAATAAAGGTTGCTTTTAAAACTCATCTAATTTTCTTGTGTGTTTTTAAAAATT
TTGATTATGCTAGTAGTTGGCTAATCAGATCCTCACTCCAGTGGTTTGCTCTGTGACGTTAGGATACTCCCATGGGATAG
AAGTTACGTATAGGGAATGTCAGATATTCTTCATTGTGCTGACTTGCTTTCGCTTACAGTTGACTTTTGTGCCCTGGTAA
TTCTGTATCCTGTTTACCGTTTACCTACTTCCCACGTCATCATGATTTCTTTTGAGGGAGAACTGAATGAAATTCCCTTA
AGGGCCTGACTTCAGCACCCGTCTCTGCAGAGGTTAGTGGCTCATACTTCCTCCCAGGAGCTGAGGTTATCGACTCTCAC
TGTTGCCTACAGAGCACAGATCCTGAACTAAATGAAACATTTACTTGGAATAATGCTAATTCTGTACATATTTTATTCCC
TAGTCCCCACTTCCCTGTTTAAAAACAAAATCTACTTAGAAAAAAATCCCTGTGAATCAGTTGTCTAATGAATTTAGCAA
GTTAAATGCCAGATTGACATTTTGCTTTATAGTTTATACAAGCATGTGTGTGTTTTTTTCTCGCAGAGAACCATGGAGTC
TGGCAGTACCGCCGCCAGTGAGGAGGCACGCAGCCTTCGAGAATGTGAGCTCTACGTCCAGAAGCATAACATTCAAGCGC
TGCTCAAAGATTCTATTGTGCAGTTGTGCACTGCTCGACCTGAGAGACCCATGGCATTCCTCAGGGAATACTTTGAGAGG
TTGGAGAAGGTAAAAATAAATGTGGGGAGATGATGAGGTGATTGTGACAGTTGTTACATTTAATAACTGGAATGTTACTA
ATTTGTATTTTTTGGAAGAAAAGGAATCTGACTAAATAAAAAGTCTAAAACAATTTCAAATAAGAAATACAGTTAAGGCA
TTTGTAGTAATTTAAAAATTCTTAATTAGTAGAATTTATCAGAAAAATGAACCTGTATGCTAACTGTACTTGGCTAATAA
AGGGTTTCCAAACAATTCTTTGTAACTTTTTAAATTAGTGCGTAGAACTATAACAGATAAAACTGATCAGAACTAGTATA
GCAGTTCTATGAATAAGAAATTCTATAGTTCTTAAAGGCAGTTAATGCTCCTCCCGTTTTGAACAAAGCAAGTAAGCGTA
GTAAATCTTATCCCACTTTTAAAACTAGTGTAATGAAACATGAATCTAGCTTGTGACTGATATATCAGAAATTTTCAATT
AGATTCGGTCTATTTTAGTATAGAGTATATCTGATAAATTACTGTAGAGATATTGATATTGATGTTCCTCAAAAATTTTA
CTCCATTTTATTGGTCAGGACTTGTTGCGCCTTGAAAAAAATTAATCCAATTTTTATTCTTTTTTGCTCTTCCTCCTTGC
TTGTATGTCATTGTGACCTACGTATATGGCATATGTTTTTCTAAGCAAAGTGATAATTTTACATCAGGGATAATTGAAGC
AAATGAATGCTTCAATTCATCTCCCTCAAGAAACGATGAATGAAAAAGTCTGGGTTACCAAATATTTTGAATAGTTTATG
TGATTCGCTTCTGTAAATCAGTGAGAGAAACTTACTGATTTTCTTGTGCATGTGGAAGTTATGAGGTGGTTCATAATGAT
TATGAATTAATTGAAATGAATCATATACCAAAAGAAATGATTCATATACCAAAAGAAATGAATCATTTCTTTTGGTATAT
GATTATCTAATTGTATAATAGAAATAATTTGCTTTATTTTCCATTGGTTTTTATAGTTTCTTATAATCAGTATAGTTTAT
TAGTAAAAGAATCTGTACTAAGCTTTAAAAAGTATTTGGGTAGCTCATTGATCAGGTATTTTCTATTTTCTTTAAAAACT
GATTGTTAAAATTTGTATTTAGTACCATGATCAGAATAATTAAAAAAAAAACAAAAACAACTAGTCACTGTGAATGTTGC
TTTGCTGTCTTGGAATTATAGTAGATATTCTGGCTTTCTCTTATTTATGCAATTTCCAAATCATGGAAGTATTGTAGAGC
CAGGTCATAGATGTAGCTTGTTTTGAAGTCAAGTGCATTCCTGGAGATCCGGTTTTGAAATGGGTCACTGTAAGGTGATC
CCTCTTCTTTGGACATCAATAGAAACCATCAAATGAGAGGATTAAGTTGGTGAGACATTAAGTGTGTATCTTTTTATAGG
GAGTGTTGAATGTGTGATGCTAGTTTCAAAGCTTGTAGTTGCCACAGTACTGTTTAAAGACTAACAAAGGTGGAAAGCAA
TAAATAATTATTAAAATGGTTTCTTTGCAGATGGAATTTTTAGATTTAATGTGTTTCAGCTTCTTTAACTTTTAATAATT
AAAGTCACAGTTCAACATGGTTTTTGCTGTAATTCAAGGGTCTTTGTTCACATGTATACATTCCTTCCAGGGTTGAATAT
AGATACCTGGACCTTTAAGTAATTAGATTTTCAACTTGTTAGTGGGTCATAGTTCTGTGTATTAGGTGTTAATTTGTATG
TTAGTCTATTAGTCCGTTGTCATGCTGCTAATAAAGACATACCGAGGCTGGGTAATTCATAAAGGAAAGAGGTTTAATTG
ACTCACAATTCAGCATGGCTGGGGAGGCCTCAGGAAACTTACAATCATGGCAGAAGGAGAAGCAAACCCATCCTCTTCAC
ATGGCAGCAGCAAGGAGAAGTACAGAGCAAAATGGGAAAAGTCCCTTATGAAACCGTCAGCTATCGTGAGGACTCACTCA
CTATCATGATAACAGCATGAGGGTAACCCCCCTGCCATGATTAAGTTACCTCCCACCAGGTCCCTCTCAGGGCACATAGG
GATTATGGGAACTGCAATTCAAGATGAGATTTGGGTGTGGACACAGCCAAACCATATCATTCCACCTCTGGCCCCTCCCA
GATCTCATGTTTTCACATTTTGAAACACAGTCATGCCTTTCCAACAGTCCCTCAGAGTCTTAACTCATTCCAGCATTAAC
TCAAAAGTTCAAGTCCAAAGTCTCATCTGAGGCAAGGCAAGTCCCTTCCACCTATGAGCCTGTAAAATCAGAAGCAAGTT
AGTTACTTCCTGGGGTCATTGGGTAGATAACACCCATTCCAAATGGGAGAACTTGGTCAAAACAAGGGGAGTATAGACCC
CGTGCAAATCCGAAATCCAACGAGGCAGTAATTAAATCTTAAAGTTGCAAAAGGATCTCCTTTGACTCCATGTCTCACAT
TCAGGGCACACTGATGCAAGAGGTGGGCTCCCGTGGCCTTGGGCAGCTCCGCCCCTGTGGCTTTGCAGGGTACAGCCCCC
CTCCTGGCTGCTTCCATGGGCAGGCATTGAGAGTCTGTTGCTTTTCCAGGTGCATGGTGCAATCTGTTGGTGGATCTACC
ATTCTGGAGTCTGGAGGATAGTGGCCCTCTTCTCGTAGTTCCATTAGGCAGTGCTGCAGTGGGGACTCGGTGTGGGGGCT
CCAAACGACCCCACATTTCCCTTCCGCACTGCCCTAGCAGAGGTTCTCCAGGAGGGCCACGCCCCTGCAGCAAACTTCTG
TCTGGGCATCCAGGCATTTCTGTACATCTTCTGAAATCTAGGGGGAGGTTCCCAAACCTCAGTTCTTGACTTCTGTGCAC
CCACAGGCCCAGCACCACTTGTAAGCCACCAGGGCTTGGGGCTTGCACTCTCTGAAGTAATGGCCAGAGCTGTACCTTTT
AGCCAAGACTGGAGCTGAAGCAGCTGGAACGCAGGGTACCATGTCCTGAGGCTGCATAGTACAGGAGCCCCAGGGCATGG
CCTAGGAAACCATTTTCCCCTCCTAGGCCTCTGGGCCTATGATGGGAGGGGCTGTCCTGAAGGTCTGTGACATGCCCTGG
AGACATTTTCCCCATTGTCTTGGTGATTAACATTTGGCTCCTTGTTACTTATGTGAATTTCTGCGGCAGGCTTGAATTTC
TCCCCAGAAAATGGGATTTTCTTTTCTATTGCTTTGTCAGGCTGCAAATTTTTCAAGCTCTGCTTCCTCTTGAATGCTTT
CCTGCTTAGAAATTTCTTCCACCGGATACCCTAAATCATTTCTCTCAAGTTCAAAGTTCCACAGATTTCTAGGGCAGGGC
CAAAATACTGCCAGTCTCTTTGCATAGCGAGAGTCACCTTTACTCCAGTTCTCAAGTTCCTCATCTCCATCTGAGACCAC
CTTAGCCTGGACTTCATTGTCCATATTACTATCAGCATTTTGGTCAAAGCCGTACAAGAAATCTCTAGGAAGTTCCAAAC
TTTCCCACATTTTCCTGTCTTCTTCTGAGCCCTCCAGACTGTTCCACCCTCTTCCTGTTACCCAGTTCCAAAGTTGCTTC
TGCATTTTTGGGTATCCTTGTAACAGCACCCCACGCTCTGTGTACCATTTTACTGTATTAGTCTGTTCTCATGCTGCTAA
TAAAAGACATACCCAAGACTGGGTAATTTATAAAGGAAAGTGGTTTGACTCACAGTTCCTCATGGCTGGGCAGGCCTCGG
GAAGCTACAATCATGGCAGAAGGGGAAGCAAACACATTCTTCTTCACATGGCAGCAGCAAGGAGAAGGGTCAAGCAAAAG
GGGGAAAAGCCCCTCAAAACTGTCAGATGTCATGAGAGCTCACTATCACCAGAACAGCATGGAGGTAACCACCCCTGTGA
TTAAATTACCTCCCACCAGGTCCCTCCCACAATATGTGGGGATTATGGGAACTATAATTCAAGATGAGATTTGGGTGGGG
ACACAGCCAAACCATATCAGTCTGAAAATACAGTCATATTCTCATCACCTTCTTCGTCATTACTGGGGGGTTGTGTTTCT
GTTACCTTCAACTACTCCATAAGAAATGTACCAAAAACTCTTGACAGTTGGTCTTTTGAAAGCTTCTGCATTTTAATTCA
GTCATCTGGAATTTGAGTCTTCTTTTACTCTTGTATTTATTAGACCCTTAGGTAAGAGGAATTAAAATAACAGTGACCTT
GTGTCTGCTGTGTCAGGTACTGTGTGAAGCACTTTATATACATAAATACTCGTTATTTCAAATGTACGAGGTATGTGATT
TTCAGCATTTTATAGACATAGCAGTAAAACTGAGAGAAATTAAGTAATGTGGCTGTGGTTATAGACTGTAGTCGTCAGCT
TTTGCTGGAGCAACATACAACCCCCAAATTTCAGTGGTTACTACAACAGACCAGTCATGTGCAGTTCTTCTGGTATCAGC
CTGTCTTATGTTCTTGACACCACATATCTTGTTCTGGGGCTGAGCAGAAGGAGCAGCCCTATATAGGGCATGCTGTTCTC
AAAGCAGAGGGAGGGCAGAAGCTCAAGGTGGACAGAGCCAAACCACACAGGCAACCATGGTATGGCATGTCCACTTACAT
TCCATGGCCAGAGCAAGTCCTGTAGCCAAGCCTTAAGTCAGTGGGGTGGGAAGTATACTTTACCCACAGGGAAGAGTGAC
AGAAGCAGGGAGGGAACAAATAATCGGGAAAACATAGTAGTGGGGACAGAATTTGAACCTAAGAGTCAAGAAGATAGTGC
AGAATTTAATGCAAAACCGAATGCAGAATTTGAACCTCAGAGTCAAGAACATAATTAACCACTGAGTAGACTGGGAGGTT
TTTTCTAATTTTTAATTTTTTATTGATATATAACATTTGTATGTTTTTATGGAGTACATGTGATATTTTACAGGCATAGA
ATGTGTAATGATCACGTCAAGGTATTTAGGTTATTCATCACCTCACTTAAAGAGCTGAGGAGGAAGGAGACTGACAGAAG
GATGACAACAGCAAGAGAAAGGATATAAAAATATATCATAGTATATACTAGAAAACTCATGATCTGAGTAATGGCTCTGA
GTTGTCAGATTAGGTTATATTCAGATTGCTGTTTTTAAAAGACTCACTAGAATCCATGAGACACTGCTAAAATCAGAATG
CTTTTGTTACTTCAAAATTAATCTTAAAAATTCAGTGAAGTAGAATGTAGTCCCAAGTGAAATGTTATTTGTGAAATTTT
TCCTGAAATTTTTGTGAAATGTCAGTGACAAATTTGGGGGTGGGAGAATTTGTGTTTTCATTTATACTCTTAAACTGTGT
GTGTGTTTTATTTTATTTTTATTATTATTTTTTTGAGACAGTCTTGCTCTGTCACCCAGGCTGGACTGCAGTGGTGCAAT
CTCGGCTCACTGCAACCTCTGCCTCCTGGGTTCAGGCGATTCTCCTGCCTCTGCCTCCTGAGTAGCTGGGGCTACAGGTG
CCTGCCACCACACCTGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATAATGGCCAGTCTGGTCTTGAACTC
CTGACCTTGTGGTCTGCCCACCTTGGCCTCCCGAAGTGTTGGGATTACAGGTGTGAGCCACCATGCCTGGCCTATTTTTT
GAGACAGGATCTCACTCTGTTGCCCAGGCCTGAGTGCAGTGGTGCGATCATGGCTCACTGCAGTCTCTACCTTCCAGGCT
CAGGTGATCCTCCTGCCTCAGCTTCCCAAGTAGCTGGGACTACAGGTGTGTGCCACCACGCCCAACTAATTTTTATGTGT
TTTTGTAGAGATGAGGTTTTACAATGTTGCCTAGGCGGGTCTCGAACTCCTGGACTCAAGTGATCTGCCACCTTCGGCCT
CCCAAAGGGTTGTGATTATAGGCGTAAGCCACTGTACCCAGTCATGTATTCTTAAACTTTAAACTTGGGAGAGACTTGAG
TTTTATACCTGTGTTAATATGAAATGAGAAAACCTTACTGGTTATTGGAACAACCAGAATTAACATGAAATGAGTTTTCT
AAAAACCATATTTTAAAAAGTAGGTTACATATTCACATATTTCAAAGTTGTGCAGGTACAAAGGGGCATAATAATGAAAG
GTCTCCCTCCCACGCCATTGCTTTTCTTGAATGCTGCCAATGTTCTGGAGATTAATATATGGGCACTTACAAATTTATAT
ATAGAAAAGAAATAACGGGTCAAATGAATGAGAAAGTAGAAGATAACACATTTTTATTTTTTCCCTTTTACTTCAGGCAC
AACAACTAATTCTTTAGATCTGAGAGGAATTTGTTTTTAAGGCTCTAGATGTGAAAAAAGGAATGTTTAATAGTTTATCT
TAGGTTTTATTTGAATTGGTCCAATAAGTAGTTTTTAAAAGCAAGTAAACTCTTTTTGTCTTTTAACTTCAAGTTTAAAC
CTTGATTACAAAGAGTGATCCTAGCTCTGCTGGGAGAAGTATTATAGATACGATCTCGTTTAAATTCGTGGTTACCATCA
CATCATTTCATTATTTGTTTTTATCTGGGATCAAACTGGAATGTGAATTCCACAGGCTCAGGACCCTCTCCTATTTGTTT
TTAATTTCCTGTTGCCTAGCATAGGTCTTGGCCTGGCAGATCCAGAAAATGGCTTATTGAGTTAATGAAATAACTCAGTA
ATCTAGACATTCTTGGATCACTATGTTGGGCTTGAATTGTTTTTCCTGATAACATTTCTTTTGGCAGGAGGGTCTCTTGC
TATCTGCAGTAGCATCCAAAAAAACCCAATTTTCAGGATTTTGTCTTGCAGTGTGTTACTGTTGTGTGCATCACAGATAA
TTGTTGTCAAGACATTAATGAATATCTGATTTGTTACTCACATGTTATGTGAGTACTAATGGCTTGTACTAATGACTTTT
GCCCATTAATAAAGGATAGCATCTGTTATCATCTGAGGTACATTCTGTTGAGAGTGTTTCAAGTGTTACTCTCTTTTTTT
CCCCTTTGGAATTGGTGTTTTCCTCTTAACTTACATTGTTAATGGAAGAAGAGATTGGAAGTGACTGAGATAGACTATCA
TTGGAACATGAGAGTGCCAGCTTTACATGCCGAAGGATCTCATTTTGCAAACTCGTAATTTCTTTCAGGAGGAGGCAAAA
CAGATTCAGAATCTGCAGAAAGCAGGCACTCGTACAGACTCAAGGGAGGATGAGATTTCTCCTCCTCCACCCAACCCAGT
GGTTAAAGGTAGGAGGCGACGAGGTGCTATCAGCGCTGAGGTCTACACGGAGGAAGATGCGGCATCCTATGTTAGAAAGG
TAGTTTTGATATTTGAATATCGGGGGGATGCTTTTGGGACCCACTTGGTGGTCATCTAGTCTCCTTTGATGAATGAATCA
TAAAATACAAAACAGGGTGGAACTTCATCCATCCTGTACAATTCTTGGGTACTGGAAAACAGGTTTCTGTAATAGCATGC
TGTCAGAGGAAATAACTAATAGTGATTATGAACTAGTGAATAATTGCATTTTGGGGTTTGTTATTTCCTTGCAGTTGTTT
TGCAGTAGAAGGAGGTGGGCGGTATTGCTTTTTCTCTTGAATCGTGATGTCCTTTTTTTGCTATCCTATTAAATGTTGTG
GCTTTTAACCTTTTATTCTACGAGCCTCATTTGTCCTGTGTTCTCCTCTTCCTCAGAGCCAGGCTATTTTGAGTTATGCT
GTTAGCCTTAAAGGGGAACAGAATTGTCCTGGCACTTGAGGCTTGTGAAGCTAACAGATCACAGATTTTTAAAATGACTA
ATTATTATAAAATACTTAGTTTTGCCTCAGAATAATGACCTTGGTCCAGGTGTTTTGATTTGTTTCTTTAGTTGTTAACT
GGGAACCAAGTACCAGACTTTATATTTAGGCCTGGCTGTAGGCAAGGGGATTAATTAGTCAATACTTGTTGAGTAGTTTA
TGGATCAAAGATAGTACAAGTGTGTTGTAGTGAAACACTACAAAGCAGTCTTGTTTAAATACCATAATGTGGCTTGACAT
TTAATTGAAGCGCAGGTTGCAAACGTGAAATGTTTTTGGTTTATGGAATTGTCATTTGACCTTCAGTTCTTTTCTAGGTT
ATACCAAAAGATTACAAGACAATGGCCGCTTTAGCCAAAGCCATTGAAAAGAATGTGCTGTTTTCACATCTTGATGATAA
TGAGAGAAGGTAGGAACAGGCTCTTTCTTAACACTATTTTTCAAGTAAGGGTGTGATCCCAAATTGTTTTCAACACTTGT
TGCAAGTTTTAGAGCTCTTAGTAATTGTTCACCAGATGACAGTCTGGGGTCTTTAATTCTAAGCTTAATGTTTGAAATTC
ACGGAAGAGACATGTGAAATGTAACACGAGGCCTTCTCTCTTTTGCAGTGATATTTTTGATGCCATGTTTTCGGTCTCCT
TTATCGCAGGAGAGACTGTGATTCAGCAAGGTAAGGGCCTCTGGAGCATGCAATATTGTTACGGGAGAGGAGGCGAGACT
AGAGGATTTTTTTGGTTTTGTTTTATTGAAGTTTGTTTTCCTCTTTGATCCTACCACTTTTTTTTTTCTGTTATACTATT
GGATTTTTCTATTTCTTTTAAATTAAGATTTTCTGAGATGGACAGAACACTTTGTATTGGGAACTAATATTTTTGATACA
GTTTTGTTTATAATTTAAAGGAAATGCCTACATTGTCTTACCTTGAATGTCATATAGAATTGCAGAATCATATATATCTC
TCATGTTCTTTATATTGTTAATCACTTTTAAAGTAAGAAATAAATGAAACACCTACATTCTTCATTGTATAGCCCTGTCT
ATTAAAAAGGTTCTAGGACTTCTATAGATTCTTACTTTGCCTATATAGACTAACATGGATCTAACTTTTTGACTATCTTC
CTCTTTTTATTTTCTTATTTATTCTTGACATTTTATGAGTGGGTATATATTTTCATTTTGTGGCAGCCTGATAATTTGTT
ATTAACTATTTGAGTTGTTTCTAATGTCCTTGTTATAAATGCCATAGCAGTTAATAACTACACATATGTAGCTTTTAAAA
ATTTTTTTCAGAGGTATTCTTCACCATGAGATGACTAAAAAAATTTTGATTAATTCTATGACTTTTAAAATATGTTGCTT
GATTTTCTTTCCCCTGAAAGATTGTGTTAGTTTGTAACACACTCTCACAGTACCACTGTAAAATAAGTTTATTGTTTTGT
AATAATTTTGATAATTTCTTTCTTTAATTTGGAATATGCTTCTAACTTTTTTACCCTCTTTTAGGTGATGAAGGGGATAA
CTTCTATGTGATTGATCAAGGAGAGACGGATGTAAGATTTACCAATATCAAAAATATGTTGATCTTAAAAGCCAATGTAT
TGATCGCTTCCGAGCAATAAGAATAGTGATTTTGAAGGGTCATTACATCCCTTGTATGTCAGATTTTATTAATACCTTTT
GCCAAGTATTTTTATGACACAGAGAAACTCTTTAAAGGTAATTTTCTGTTCAGAACTTTGCTGGAGTGGTGGTGAAGAAG
TGTGTGTAGCTGGGTGCAGTGGCCGATGCCTATAATCCCAGCACTTTGGGAGATGGAGGCAAGAGGGTTGCTTGAGCCCA
GGAGTTCAAGACCAGCCTGGGCAACAAAGTGAAACCTCATCTCTTAAAAAAAAAAAAAAAAAAAGATTCTAGACCCAGCC
ATTAGCTAGCAAAATTAATATACCTTTCTTATTCACAAATGAAATGGGGACAATAATAGCATTGATCTTTTAGGATTATT
AGAAGATTCAGTGACCTAATGCAAGTAAAATGTTTAGCATAGTGCTCAGCACGGTTCTCTAAGTATCTGTGACTGGTATT
AGTGCTTAGCTGACCTTTTTCCCTTACATCCTTACAGAGTGCTTTTTTCTTATCAGATAATTAAATCAGGTAAATTATAG
ACACTCTTAACTCATTTAACTCGTCAGAAATCACCTATTCTTCTCTGTTGTGTACTGCAAACATAATATATTCTGTTTTT
TAAAACAAAGTTCAGGATTGTGACCTTTTAAAAAGGTTTGAGGGTTTTTAACATTTAAGTGTTTGTATCTAGAAAATAAA
CTTTTTTGATGTCACTTGCACTTTAGGTCTATGTTAACAATGAATGGGCAACCAGTGTTGGGGAAGGAGGGAGCTTTGGA
GAACTTGCTTTGATTTATGGAACACCGAGAGCAGCCACTGTCAAAGCAAAGACAAATGTGAAATTGTGGGGCATCGACCG
AGACAGCTATAGAAGAATCCTCATGGTAAGAGACCATGGTGTTTGAGAGTGTGATTTAGAATTCTCATCTACGTAACTAA
TGTTTGAATATTACCAAATTAAAAAGAGAATATTTCTTTTAATGAGCAAATATTTCTTTCTTTTAATAAGCGAATATTTT
TCTTTTAATGAGCAAATACTTTGCATTAAGCCCAGCTTAGCATTATTCATTATGCCATTTTAGGCAGTGATATTTTAGAA
CAAAACCTTGGGAAACAAGATCTGGTATATATGTGCTGGTCATCTCATGTTTGGAAATCTATCCATTTGCTGGTAGGCAC
ATCTTAATTTACCTAGTTATACCCATTACAGCATGATAGGTGCTGCTTTTAAGTGCTTAAAGTTATTTGGGGCCATTCAG
AAATAATCAGCTTCCCTAACCTGTGAAAGTGGGTTATCAGTAATGTATATGTATGTCATGTCCCCTCTCGTTAAAGGAAT
AAACAAAATACTAAAACCATTGGAACTTTCTGGTGATAGTCAGATTTTTTGAGAACGTTGTGATAAATTTATAGGATAGC
TTTGGATGTTTAAGTCTCAGCCAATGCATTGGTCATTTTTAATGGTTTTCTTAAATTTGTGCAGTGTCCATCTGACCATT
TGAAAATGTACAGCCTGATGTACTTTGAAATTTTTCTGCATTTGGGATATATAGATAGATTAGATTAGATAGATAGTCTT
GTCCTTCGCAGCAACATAGATAGAGCTGGAGGCCATTTTTCTAAGCAAAATAACACAGGAACAGAAAACCAAACCACATG
TTCTCACTTACAGTTGGGAGCTAAGCAATGAGAACACGTGGATACTAGAAGGGGAACAACAAACACTGGGGCCTACTTGA
GGGTGGAGGGTGGGAAGAGGGAGAGGATCAGGAAAAATACCTGTGGTGTACTTTACTTATTACCTGGGCAACAAAATTAC
CTGAACACCAAACCCCTGTGACACCCAGTTTACCTATATAACCTGCACATGTACCCCTGAACCTTAAACCCACACACACA
AAAAAACGCTTATGGCAAAGATAAGTCTAAATTTTAGAAAGATTGGTTTTGAAGTGATGTGACAGTCTACTGGAGAAGAA
ACTGACCATACAGTTAGTTCTGCATTTCCTCTACAGGAATACTATTAGTAAAAGGAAACATAGAATGTTTACAGCTTTAT
CTCATTGTCAAAGAAGGAAGAGGTAGGACCTGGAACTATTGGTTTGAAATAAAATATTTTACTTTCTCATAGTGGGCCTG
AAAGGAAATTAGGGCCTCACAATGCTTTGGCTTTGTGGACAGGAATTAGGAACTGTAGATATGGGGTGAAATATCTATAT
AGCTGGGTAGGGGAGGATATGGTCCTTTTTTTATAGAATAAAGACATGTCAATTGTATAGGTGAGAAGCCAGAACTAATG
GAGGAATCTGCATTTAAATACCAGCGTTGAACAGGAAGAACACTAGGATTATTGGGTTGTAAATGACCTAGATTACTTTT
GTGAGAAAATATTTTCAGAGATAAATTGGGTTGGCAGTGGCACAAAATCAGTTTGAGAGTAAACATGGAAATTGGACATT
GGTTTAAAGTGTGTGGAAAAATATCTTGAGTGATAGGCTCAGGTATAAACCGGTATTTCGACTGTATTTGGAAGTTGGGA
AATGCTTTGTGAAATATGTCAACATACTGGTTGCAAATGCTAGGAATTGGGCATAATATTGGCGGAAAATAAAAATCACA
AGAATGTCATATCATTCATTACCTGTAAAATAAAAATGAATTAGTTAAAATTAAACTTTCCTCATTAAAAGCAACAAGCT
TTGACTTTCTGGTTTTAAAATTTATTTGAAACTTAATATTTATTATTCCATAGCATTATGTGGTGATAATTACACGTCTT
GGGGATATCACTTTTGTTATTTTTATTTTTAGGGAAGCACACTGAGAAAGCGGAAGATGTATGAGGAATTCCTTAGTAAA
GTCTCTATTTTAGGTGAGTTGTAAAGTGTGTTAACTTTGCTAGTATGTGAGATACCCCTGAATTAGAATTGGATGGACTT
GGGAAAAGCCTTCTGAAAGTATAATTGCTACTCATTCCCCCTGAAAAGACAGAAGGGCTGAAAGTCCTTCTGACTGTGGA
CATTCACAGTTATTTCCTCTGTGACTTCCCGTCTCTCTTGTTCCATCATTGAGTTGATTGGTTCAGAAAAGTGAGTACTT
CCAACAATACATTTCCTCTGTGGAAAGATTAGGTATCATTTGCTGGCATCCTCTGAAAACATGCCAGAAGTTTGTTGAAA
TTTAGAGTAAAGCAGATTAATTGAAGATATTCTTTTGTGCATTTTGTTATGTGGACTTGGAGATGTTAGAACTTGTTCTT
CATGAAAGGGGAATGGGGATTTTTATAAGGTAACAGGCTTCTGCCATTGTTTATTACAGTGAATTTTTCACCTCTTCTTT
GTCTTTTCTTTGAATTGGTTACATATGCTTTGTGTTTTGGATAGTAGTTTGGCCTTTGGGAATAAAAGTTATTTTCTAGT
TCTTTTTCATAAAGTAAACCAAGAATTTAAATAGATTAAATTATTTCTATGAAACTTTGGAACGATATGGATGGGGAAAC
TATGACTTTTGAGTATTGTAGTTGTAGGTTTGATTTGCATTGATGGCAATCTTCAGGAATACTTAAGGATTACATTTTCT
TATTCCCTTGCCATTTGGTACAGTTGGTATAAATTAACCTAGCCACTGGGCTACCGAAGTAAGGATCTAAGGGCTATCTG
CAGGCAGTATGAGAATCCTGCTCAGACTAGAGGTAATTGAAGACAGGTACCACTTTTAATCTGAGACACTACTAGAATGT
TGAATGGGCATGGCTATTTGGTTGAATCTCTTTATACTTTCTTTTTACCTTTATAACAGCACCAAATAATACAGAGCAGT
TATTTTGATTCTTGTCTTTCAGAGTCTCTGGACAAGTGGGAACGTCTTACGGTAGCTGATGCATTGGAACCAGTGCAGTT
TGAAGATGGGCAGAAGATTGTGGTGCAGGGAGAACCAGGGGATGAGTTCTTCATTATTTTAGAGGTAAAGAACTCAGAAT
TTAATACTTGAATTTTAGAGGTAAAGAACTCAGAATTTAATACTTTAAAAAGTTGTACGCTCTAAGAGGGAAAGAGTGGG
CTAATTCTGAACTATAGCTTTAGTTTTTAAGAATACCTGACCATTTTATTTTAAAATTATCTTTTACTTTGAAATGCTGT
TGTTTGGTTTTCTGCCAGGTCACTATATTTTTAAATGAGTTTGAGTCAGAATTCTTGAAGGGCCCTAGACATGAAAAGCC
AAATTCTAAAAACCATTTAACATAACAAACTGTGATGATTCTGCACTATTCTTGTTAAAATGCAAGTGTTTGGGCTATTT
GGCAAATAAGGATTAAAGGTAATTATTTAAATTTGAAAAATTACTGTGTTTGTATATCTCCACATTCCATGGAAATGTAT
AGCAGATACTCTTGCTAAGCGGATCCAAGTGGCAGATTTCTATGAATGTGGCTCCATAGTTGCTAATTGATTTTATTTAA
ATCAGGGGTCAGGAGACTGTAAAGGGCCAGGTGGTAAGTAAGTTAAGCTTTGTGGACCATAGGGTTTCATTCGCAAAGTC
TCAACTCTTGTCATAGTGCAAAAGCAGCCACAAATAATATGTAAATGAATGTATGTGGTATTTCAGTAAAGTTTGATTTG
CGAAAGAGACAGTGAGCTTGGATTTAGCCCTTCATCTACAGTTTGCTAACCCAAGTGTGCACCCTTTAAGCACCTTAGCT
TGATACGAAGAACCTCGCTAGCAGGAGATGCTGGTAAAATAGAAATTGAAGCTCATGTGGTGACTAACTTTAAAGTCATT
TTTTATCATATGCACACATTTGCAAGGTAGTTAAAATTGCATAGGATGTTTAAGGTGCCACCCTGGGTTTGAGAGTGTGT
GTTTGTTTAGCTTTTTGGTGATTTTATTATAGGGGTCAGCTGCTGTGCTACAACGTCGGTCAGAAAATGAAGAGTTTGTT
GAAGTGGGAAGATTGGGGCCTTCTGATTATTTTGGTATGTATGAATTCCCTCACAATAAATACATGGTTTCTTTAAGTCA
CCTCTCAGTGAGATATTGTAGTCTTCCATAATTTTGTCTTCTCCTGAATTTTATTTTCTAACTGCAGTCTTTTTTGGCTC
TGAGAGGGAAGGTGTGAGATTTTGATCTTTACTCATTTAATGAAATTACTGATTGTCTCATATCTATTGTCTTCTTTCTC
AGAAGTGCACTGCTTTAAGGAAATGTTTTTCATAGAAGTTAGCCTGTTACCCATCTTTGCTTTCTCCAGGTGAAATTGCA
CTACTGATGAATCGTCCTCGTGCTGCCACAGTTGTTGCTCGTGGCCCCTTGAAGTGCGTTAAGCTGGACCGACCTAGATT
TGAACGTGTTCTTGGCCCATGCTCAGACATCCTCAAACGAAACATCCAGCAGTACAACAGTTTTGTGTCACTGTCTGTCT
GAAATCTGCCTCCTGTGCCTCCCTTTTCTCCTCTCCCCAATCCATGCTTCACTCATGCAAACTGCTTTATTTTCCCTACT
TGCAGCGCCAAGTGGCCACTGGCATCGCAGCTTCCTGTCTGTTTATATATTGAAAGTTGCTTTTATTGCACCATTTTCAA
TTTGGAGCATTAACTAAATGCTCATACACAGTTAAATAAATAGAAAGAGTTCTATGGAGACTTTGCTGTTACTGCTTCTC
TTTGTGCAGTGTTAGTATTCACCCTGGGCAGTGAGTGCCATGCTTTTTGGTGAGGGCAGATCCCAGCACCTATTGAATTA
CCATAGAGTAATGATGTAACAGTGCAAGATTTTTTTTTTAAGTGACATAATTGTCCAGTTATAAGCGTATTTAGACTGTG
GCCATATATGCTGTATTTCTTTGTAGAATAAATGGTTTCTCATTAAACTCTAAAGATTAGGGAAAATGGATATAGAAAAT
CTTAGTATAGTAGAAAGACATCTGCCTGTAATTAAACTAGTTTAAGGGTGGAAAAATGCCCATTTTTGCTAATTATCAAT
GGGATATGATTGGTTCAGTTTTTTTTTTTCCAGAGTTGTTGTTTGCCAAGCTAATCTGCCTGGTTTTATTTATATCTTGT
TATTAATGTTTCTTCTCCAATTCTGAAATACTTTTGAGTATGGCTATCTATACCTGCCTTTTAAGTTTGAAACTAACTCA
TAGATTGCAAATATTGGTTAGTATTTAACTACATCTGCCTCGGCTCACAAATTCCGATTAGACCTTTATCCAGCTAGTGC
CAAATAATTGATCAGATGCTGAATTGAGAATAAGAATTTGAGGTCTACATTCTTGGTTGTTAATTTAGAGCGTTTGGTTA
AAGTATGTCCTTCAGCTGACTCCAGTATAATCTCCTCTGCTCATTAAACTGATTCCAGGAGATTGGATTTGCTGTGACTA
GATACAGATGGAGCAAATGTCCTAACAGAGAAATAGAGGTGATGCTGCTAAAGGGAGAAATGCCAGGCGGACAAAGTTCA
GTGTCGGGAATTTTCCCCGTGACATTCACTGGGGCATGAGATTTTGGAAGAAGTTTTTTACTTTGGTTTAGTCTTTTTTT
CCTTCCTTTTTATTCAGCTAGAATTTCTGGTGGGTTGATGGTAGGGTATAATGTGTCTGTGTTGCTTCAAATTGGTCTGA
AAGGCTATCCTGCTGAAAGTCCTGCTTTCCTATCTAGCATTTATTTCTCTGGCAAACTTTTCTTTCTTTTCTTTTTTAAA
GTAAACTTGTGTATTGAGTCTTAACTGTATTTCAGTATTTTCCAGCCTTATGTGTTACATTATTCCAATGATACCCAACA
GTTTATTTTTATTATTTTTTTAAACAAAATTTCACAGTTCTGTAATGTAGGCACTTTTATTTTCATTGTGATTTATATAT
AAGGTAATGTAGGGTTATATTTGGGAGTGACTGCAAGCATTTTTCCATCTGTGTGCAACTAACTGACTCTGTTATTGATC
CCTTCTCCTGCCCTTTCCCAGGTAATTTAAATTGGTCATGGTAGATTTTTTTCATAGATTTGAAAAACTTTTAGGTTGTT
ACCAAGTATGAAGTATAAATCTGGGGAAGAGGTTTTATTTACATTTTAGGGTGGGTAAGAAAGCCACCTTGTTACAAATT
TTTTAATTTCCAAAATAATCTATATTAAATGAGGGTTTCTGATCTGTACTTTGTGTTTAGCTACCTTTTTATATTTAAAA
AATTAAAAATGAAAATTACGTTCTTACAAGCTTAAAGCTTGATTTGATCTTTGTTTAAATGCCAAAATGTACTTAAATGA
GTTACTTAGAATGCCATAAAATTGCAGTTTCATGTATGTATATAATCATGCTCATGTATATTTAGTTACGTATAATGCTT
TCTGAGTGAGTTTTACTCTTAAATCATTTGGTTAAATCATTTGGCTTGCTGTTTACTCCCTTCTGTAGTTTTTAATTAAA
AACTTTAAAGATAAGTCTACATTAAACAATGATCACATCTAAAGCTTTATCTTTGTGTAATCTAAGTATATGTGAGAAAT
CAGAATTGGCATAATTTGTCTTAGTTGATATTCAAGGCTTTAAAAGTCATTATTCCTGGGCTTGGTAAGTGAATTTATGA
GATTTACTGCTCTAGAAAGTATAGATGGCCAAAGGACCGTTTTGTATTGCTTCCTGATTACCAGTCTGATTATACCATGT
GTGCTAATATACTTTTTTTGTTATAGATTGTCTTAATGGTAGGTCAAGTAATAAAAAGAGATGAAATAATTTAAATTCTT
AA
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Primary source |
RefSeq : NM_002734.3 (GI:47132579)
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Name |
Protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) (PRKAR1A), transcript variant 1
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Type of transcript |
mRNA
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Organism |
Homo sapiens
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Length |
3626 nt
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Map |
17q23-q24
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Location |
Chromosome 17 (NC_000017.10) strand : +
66508542...66508688 | 66511534...66511716 | 66518896...66519066 | 66519865...66519956 |
66520156...66520217 | 66521052...66521098 | 66521894...66522052 | 66523980...66524040 |
66525010...66525131 | 66526060...66526141 | 66526417...66528910 |
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Exon(s) |
Start |
End |
Length |
is coding |
Exon 2a
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1
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147
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147
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1
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Exon 3
|
148
|
330
|
183
|
1
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Exon 4
|
331
|
501
|
171
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1
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Exon 5
|
502
|
593
|
92
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1
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Exon 6
|
594
|
655
|
62
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1
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Exon 7
|
656
|
702
|
47
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1
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Exon 8
|
703
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861
|
159
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1
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Exon 9
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862
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922
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61
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1
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Exon 10
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923
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1044
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122
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1
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Exon 11
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1045
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1126
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82
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1
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Exon 12
|
1127
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3620
|
2494
|
1
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Primary source |
NCBI : CCDS11678
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Nucleotide |
PRKAR1A, mRNA isoform 1[NM_002734.3] : 154...1299
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Length |
1146
|
Location |
Chromosome 17 (NC_000017.10) strand : +
66511540...66511716 | 66518896...66519066 | 66519865...66519956 | 66520156...66520217 |
66521052...66521098 | 66521894...66522052 | 66523980...66524040 | 66525010...66525131 |
66526060...66526141 | 66526417...66526589 |
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Start codon |
1
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Translation |
NP_002725.1 |
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1 |
GATTGGCTGC |
GGCCAGGCCG |
TTTCCGGTGG |
AGCTGTCGCC |
TAGCCGCTAT |
CGCAGAGTGG |
AGCGGGGCTG |
GGAGCAAAGC |
|
81 |
GCTGAGGGAG |
CTCGGTACGC |
CGCCGCCTCG |
CACCCGCAGC |
CTCGCGCCCG |
CCGCCGCCCG |
TCCCCAGAGA |
ACCATGGAGT |
|
161 |
CTGGCAGTAC |
CGCCGCCAGT |
GAGGAGGCAC |
GCAGCCTTCG |
AGAATGTGAG |
CTCTACGTCC |
AGAAGCATAA |
CATTCAAGCG |
|
241 |
CTGCTCAAAG |
ATTCTATTGT |
GCAGTTGTGC |
ACTGCTCGAC |
CTGAGAGACC |
CATGGCATTC |
CTCAGGGAAT |
ACTTTGAGAG |
|
321 |
GTTGGAGAAG |
GAGGAGGCAA |
AACAGATTCA |
GAATCTGCAG |
AAAGCAGGCA |
CTCGTACAGA |
CTCAAGGGAG |
GATGAGATTT |
|
401 |
CTCCTCCTCC |
ACCCAACCCA |
GTGGTTAAAG |
GTAGGAGGCG |
ACGAGGTGCT |
ATCAGCGCTG |
AGGTCTACAC |
GGAGGAAGAT |
|
481 |
GCGGCATCCT |
ATGTTAGAAA |
GGTTATACCA |
AAAGATTACA |
AGACAATGGC |
CGCTTTAGCC |
AAAGCCATTG |
AAAAGAATGT |
|
561 |
GCTGTTTTCA |
CATCTTGATG |
ATAATGAGAG |
AAGTGATATT |
TTTGATGCCA |
TGTTTTCGGT |
CTCCTTTATC |
GCAGGAGAGA |
|
641 |
CTGTGATTCA |
GCAAGGTGAT |
GAAGGGGATA |
ACTTCTATGT |
GATTGATCAA |
GGAGAGACGG |
ATGTCTATGT |
TAACAATGAA |
|
721 |
TGGGCAACCA |
GTGTTGGGGA |
AGGAGGGAGC |
TTTGGAGAAC |
TTGCTTTGAT |
TTATGGAACA |
CCGAGAGCAG |
CCACTGTCAA |
|
801 |
AGCAAAGACA |
AATGTGAAAT |
TGTGGGGCAT |
CGACCGAGAC |
AGCTATAGAA |
GAATCCTCAT |
GGGAAGCACA |
CTGAGAAAGC |
|
881 |
GGAAGATGTA |
TGAGGAATTC |
CTTAGTAAAG |
TCTCTATTTT |
AGAGTCTCTG |
GACAAGTGGG |
AACGTCTTAC |
GGTAGCTGAT |
|
961 |
GCATTGGAAC |
CAGTGCAGTT |
TGAAGATGGG |
CAGAAGATTG |
TGGTGCAGGG |
AGAACCAGGG |
GATGAGTTCT |
TCATTATTTT |
|
1041 |
AGAGGGGTCA |
GCTGCTGTGC |
TACAACGTCG |
GTCAGAAAAT |
GAAGAGTTTG |
TTGAAGTGGG |
AAGATTGGGG |
CCTTCTGATT |
|
1121 |
ATTTTGGTGA |
AATTGCACTA |
CTGATGAATC |
GTCCTCGTGC |
TGCCACAGTT |
GTTGCTCGTG |
GCCCCTTGAA |
GTGCGTTAAG |
|
1201 |
CTGGACCGAC |
CTAGATTTGA |
ACGTGTTCTT |
GGCCCATGCT |
CAGACATCCT |
CAAACGAAAC |
ATCCAGCAGT |
ACAACAGTTT |
|
1281 |
TGTGTCACTG |
TCTGTCTGAA |
ATCTGCCTCC |
TGTGCCTCCC |
TTTTCTCCTC |
TCCCCAATCC |
ATGCTTCACT |
CATGCAAACT |
|
1361 |
GCTTTATTTT |
CCCTACTTGC |
AGCGCCAAGT |
GGCCACTGGC |
ATCGCAGCTT |
CCTGTCTGTT |
TATATATTGA |
AAGTTGCTTT |
|
1441 |
TATTGCACCA |
TTTTCAATTT |
GGAGCATTAA |
CTAAATGCTC |
ATACACAGTT |
AAATAAATAG |
AAAGAGTTCT |
ATGGAGACTT |
|
1521 |
TGCTGTTACT |
GCTTCTCTTT |
GTGCAGTGTT |
AGTATTCACC |
CTGGGCAGTG |
AGTGCCATGC |
TTTTTGGTGA |
GGGCAGATCC |
|
1601 |
CAGCACCTAT |
TGAATTACCA |
TAGAGTAATG |
ATGTAACAGT |
GCAAGATTTT |
TTTTTTAAGT |
GACATAATTG |
TCCAGTTATA |
|
1681 |
AGCGTATTTA |
GACTGTGGCC |
ATATATGCTG |
TATTTCTTTG |
TAGAATAAAT |
GGTTTCTCAT |
TAAACTCTAA |
AGATTAGGGA |
|
1761 |
AAATGGATAT |
AGAAAATCTT |
AGTATAGTAG |
AAAGACATCT |
GCCTGTAATT |
AAACTAGTTT |
AAGGGTGGAA |
AAATGCCCAT |
|
1841 |
TTTTGCTAAT |
TATCAATGGG |
ATATGATTGG |
TTCAGTTTTT |
TTTTTTCCAG |
AGTTGTTGTT |
TGCCAAGCTA |
ATCTGCCTGG |
|
1921 |
TTTTATTTAT |
ATCTTGTTAT |
TAATGTTTCT |
TCTCCAATTC |
TGAAATACTT |
TTGAGTATGG |
CTATCTATAC |
CTGCCTTTTA |
|
2001 |
AGTTTGAAAC |
TAACTCATAG |
ATTGCAAATA |
TTGGTTAGTA |
TTTAACTACA |
TCTGCCTCGG |
CTCACAAATT |
CCGATTAGAC |
|
2081 |
CTTTATCCAG |
CTAGTGCCAA |
ATAATTGATC |
AGATGCTGAA |
TTGAGAATAA |
GAATTTGAGG |
TCTACATTCT |
TGGTTGTTAA |
|
2161 |
TTTAGAGCGT |
TTGGTTAAAG |
TATGTCCTTC |
AGCTGACTCC |
AGTATAATCT |
CCTCTGCTCA |
TTAAACTGAT |
TCCAGGAGAT |
|
2241 |
TGGATTTGCT |
GTGACTAGAT |
ACAGATGGAG |
CAAATGTCCT |
AACAGAGAAA |
TAGAGGTGAT |
GCTGCTAAAG |
GGAGAAATGC |
|
2321 |
CAGGCGGACA |
AAGTTCAGTG |
TCGGGAATTT |
TCCCCGTGAC |
ATTCACTGGG |
GCATGAGATT |
TTGGAAGAAG |
TTTTTTACTT |
|
2401 |
TGGTTTAGTC |
TTTTTTTCCT |
TCCTTTTTAT |
TCAGCTAGAA |
TTTCTGGTGG |
GTTGATGGTA |
GGGTATAATG |
TGTCTGTGTT |
|
2481 |
GCTTCAAATT |
GGTCTGAAAG |
GCTATCCTGC |
TGAAAGTCCT |
GCTTTCCTAT |
CTAGCATTTA |
TTTCTCTGGC |
AAACTTTTCT |
|
2561 |
TTCTTTTCTT |
TTTTAAAGTA |
AACTTGTGTA |
TTGAGTCTTA |
ACTGTATTTC |
AGTATTTTCC |
AGCCTTATGT |
GTTACATTAT |
|
2641 |
TCCAATGATA |
CCCAACAGTT |
TATTTTTATT |
ATTTTTTTAA |
ACAAAATTTC |
ACAGTTCTGT |
AATGTAGGCA |
CTTTTATTTT |
|
2721 |
CATTGTGATT |
TATATATAAG |
GTAATGTAGG |
GTTATATTTG |
GGAGTGACTG |
CAAGCATTTT |
TCCATCTGTG |
TGCAACTAAC |
|
2801 |
TGACTCTGTT |
ATTGATCCCT |
TCTCCTGCCC |
TTTCCCAGGT |
AATTTAAATT |
GGTCATGGTA |
GATTTTTTTC |
ATAGATTTGA |
|
2881 |
AAAACTTTTA |
GGTTGTTACC |
AAGTATGAAG |
TATAAATCTG |
GGGAAGAGGT |
TTTATTTACA |
TTTTAGGGTG |
GGTAAGAAAG |
|
2961 |
CCACCTTGTT |
ACAAATTTTT |
TAATTTCCAA |
AATAATCTAT |
ATTAAATGAG |
GGTTTCTGAT |
CTGTACTTTG |
TGTTTAGCTA |
|
3041 |
CCTTTTTATA |
TTTAAAAAAT |
TAAAAATGAA |
AATTACGTTC |
TTACAAGCTT |
AAAGCTTGAT |
TTGATCTTTG |
TTTAAATGCC |
|
3121 |
AAAATGTACT |
TAAATGAGTT |
ACTTAGAATG |
CCATAAAATT |
GCAGTTTCAT |
GTATGTATAT |
AATCATGCTC |
ATGTATATTT |
|
3201 |
AGTTACGTAT |
AATGCTTTCT |
GAGTGAGTTT |
TACTCTTAAA |
TCATTTGGTT |
AAATCATTTG |
GCTTGCTGTT |
TACTCCCTTC |
|
3281 |
TGTAGTTTTT |
AATTAAAAAC |
TTTAAAGATA |
AGTCTACATT |
AAACAATGAT |
CACATCTAAA |
GCTTTATCTT |
TGTGTAATCT |
|
3361 |
AAGTATATGT |
GAGAAATCAG |
AATTGGCATA |
ATTTGTCTTA |
GTTGATATTC |
AAGGCTTTAA |
AAGTCATTAT |
TCCTGGGCTT |
|
3441 |
GGTAAGTGAA |
TTTATGAGAT |
TTACTGCTCT |
AGAAAGTATA |
GATGGCCAAA |
GGACCGTTTT |
GTATTGCTTC |
CTGATTACCA |
|
3521 |
GTCTGATTAT |
ACCATGTGTG |
CTAATATACT |
TTTTTTGTTA |
TAGATTGTCT |
TAATGGTAGG |
TCAAGTAATA |
AAAAGAGATG |
|
3601 |
AAATAATTTA |
AATTCTTAAA |
AAAAAA |
|
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|
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|
>gi|47132579|ref|NM_002734.3|Protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) (PRKAR1A), transcript variant 1
GATTGGCTGCGGCCAGGCCGTTTCCGGTGGAGCTGTCGCCTAGCCGCTATCGCAGAGTGGAGCGGGGCTGGGAGCAAAGC
GCTGAGGGAGCTCGGTACGCCGCCGCCTCGCACCCGCAGCCTCGCGCCCGCCGCCGCCCGTCCCCAGAGAACCATGGAGT
CTGGCAGTACCGCCGCCAGTGAGGAGGCACGCAGCCTTCGAGAATGTGAGCTCTACGTCCAGAAGCATAACATTCAAGCG
CTGCTCAAAGATTCTATTGTGCAGTTGTGCACTGCTCGACCTGAGAGACCCATGGCATTCCTCAGGGAATACTTTGAGAG
GTTGGAGAAGGAGGAGGCAAAACAGATTCAGAATCTGCAGAAAGCAGGCACTCGTACAGACTCAAGGGAGGATGAGATTT
CTCCTCCTCCACCCAACCCAGTGGTTAAAGGTAGGAGGCGACGAGGTGCTATCAGCGCTGAGGTCTACACGGAGGAAGAT
GCGGCATCCTATGTTAGAAAGGTTATACCAAAAGATTACAAGACAATGGCCGCTTTAGCCAAAGCCATTGAAAAGAATGT
GCTGTTTTCACATCTTGATGATAATGAGAGAAGTGATATTTTTGATGCCATGTTTTCGGTCTCCTTTATCGCAGGAGAGA
CTGTGATTCAGCAAGGTGATGAAGGGGATAACTTCTATGTGATTGATCAAGGAGAGACGGATGTCTATGTTAACAATGAA
TGGGCAACCAGTGTTGGGGAAGGAGGGAGCTTTGGAGAACTTGCTTTGATTTATGGAACACCGAGAGCAGCCACTGTCAA
AGCAAAGACAAATGTGAAATTGTGGGGCATCGACCGAGACAGCTATAGAAGAATCCTCATGGGAAGCACACTGAGAAAGC
GGAAGATGTATGAGGAATTCCTTAGTAAAGTCTCTATTTTAGAGTCTCTGGACAAGTGGGAACGTCTTACGGTAGCTGAT
GCATTGGAACCAGTGCAGTTTGAAGATGGGCAGAAGATTGTGGTGCAGGGAGAACCAGGGGATGAGTTCTTCATTATTTT
AGAGGGGTCAGCTGCTGTGCTACAACGTCGGTCAGAAAATGAAGAGTTTGTTGAAGTGGGAAGATTGGGGCCTTCTGATT
ATTTTGGTGAAATTGCACTACTGATGAATCGTCCTCGTGCTGCCACAGTTGTTGCTCGTGGCCCCTTGAAGTGCGTTAAG
CTGGACCGACCTAGATTTGAACGTGTTCTTGGCCCATGCTCAGACATCCTCAAACGAAACATCCAGCAGTACAACAGTTT
TGTGTCACTGTCTGTCTGAAATCTGCCTCCTGTGCCTCCCTTTTCTCCTCTCCCCAATCCATGCTTCACTCATGCAAACT
GCTTTATTTTCCCTACTTGCAGCGCCAAGTGGCCACTGGCATCGCAGCTTCCTGTCTGTTTATATATTGAAAGTTGCTTT
TATTGCACCATTTTCAATTTGGAGCATTAACTAAATGCTCATACACAGTTAAATAAATAGAAAGAGTTCTATGGAGACTT
TGCTGTTACTGCTTCTCTTTGTGCAGTGTTAGTATTCACCCTGGGCAGTGAGTGCCATGCTTTTTGGTGAGGGCAGATCC
CAGCACCTATTGAATTACCATAGAGTAATGATGTAACAGTGCAAGATTTTTTTTTTAAGTGACATAATTGTCCAGTTATA
AGCGTATTTAGACTGTGGCCATATATGCTGTATTTCTTTGTAGAATAAATGGTTTCTCATTAAACTCTAAAGATTAGGGA
AAATGGATATAGAAAATCTTAGTATAGTAGAAAGACATCTGCCTGTAATTAAACTAGTTTAAGGGTGGAAAAATGCCCAT
TTTTGCTAATTATCAATGGGATATGATTGGTTCAGTTTTTTTTTTTCCAGAGTTGTTGTTTGCCAAGCTAATCTGCCTGG
TTTTATTTATATCTTGTTATTAATGTTTCTTCTCCAATTCTGAAATACTTTTGAGTATGGCTATCTATACCTGCCTTTTA
AGTTTGAAACTAACTCATAGATTGCAAATATTGGTTAGTATTTAACTACATCTGCCTCGGCTCACAAATTCCGATTAGAC
CTTTATCCAGCTAGTGCCAAATAATTGATCAGATGCTGAATTGAGAATAAGAATTTGAGGTCTACATTCTTGGTTGTTAA
TTTAGAGCGTTTGGTTAAAGTATGTCCTTCAGCTGACTCCAGTATAATCTCCTCTGCTCATTAAACTGATTCCAGGAGAT
TGGATTTGCTGTGACTAGATACAGATGGAGCAAATGTCCTAACAGAGAAATAGAGGTGATGCTGCTAAAGGGAGAAATGC
CAGGCGGACAAAGTTCAGTGTCGGGAATTTTCCCCGTGACATTCACTGGGGCATGAGATTTTGGAAGAAGTTTTTTACTT
TGGTTTAGTCTTTTTTTCCTTCCTTTTTATTCAGCTAGAATTTCTGGTGGGTTGATGGTAGGGTATAATGTGTCTGTGTT
GCTTCAAATTGGTCTGAAAGGCTATCCTGCTGAAAGTCCTGCTTTCCTATCTAGCATTTATTTCTCTGGCAAACTTTTCT
TTCTTTTCTTTTTTAAAGTAAACTTGTGTATTGAGTCTTAACTGTATTTCAGTATTTTCCAGCCTTATGTGTTACATTAT
TCCAATGATACCCAACAGTTTATTTTTATTATTTTTTTAAACAAAATTTCACAGTTCTGTAATGTAGGCACTTTTATTTT
CATTGTGATTTATATATAAGGTAATGTAGGGTTATATTTGGGAGTGACTGCAAGCATTTTTCCATCTGTGTGCAACTAAC
TGACTCTGTTATTGATCCCTTCTCCTGCCCTTTCCCAGGTAATTTAAATTGGTCATGGTAGATTTTTTTCATAGATTTGA
AAAACTTTTAGGTTGTTACCAAGTATGAAGTATAAATCTGGGGAAGAGGTTTTATTTACATTTTAGGGTGGGTAAGAAAG
CCACCTTGTTACAAATTTTTTAATTTCCAAAATAATCTATATTAAATGAGGGTTTCTGATCTGTACTTTGTGTTTAGCTA
CCTTTTTATATTTAAAAAATTAAAAATGAAAATTACGTTCTTACAAGCTTAAAGCTTGATTTGATCTTTGTTTAAATGCC
AAAATGTACTTAAATGAGTTACTTAGAATGCCATAAAATTGCAGTTTCATGTATGTATATAATCATGCTCATGTATATTT
AGTTACGTATAATGCTTTCTGAGTGAGTTTTACTCTTAAATCATTTGGTTAAATCATTTGGCTTGCTGTTTACTCCCTTC
TGTAGTTTTTAATTAAAAACTTTAAAGATAAGTCTACATTAAACAATGATCACATCTAAAGCTTTATCTTTGTGTAATCT
AAGTATATGTGAGAAATCAGAATTGGCATAATTTGTCTTAGTTGATATTCAAGGCTTTAAAAGTCATTATTCCTGGGCTT
GGTAAGTGAATTTATGAGATTTACTGCTCTAGAAAGTATAGATGGCCAAAGGACCGTTTTGTATTGCTTCCTGATTACCA
GTCTGATTATACCATGTGTGCTAATATACTTTTTTTGTTATAGATTGTCTTAATGGTAGGTCAAGTAATAAAAAGAGATG
AAATAATTTAAATTCTTAAAAAAAAA
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Primary source |
RefSeq : NM_212471.1 (GI:47132580)
|
Name |
Protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) (PRKAR1A), transcript variant 2
|
Type of transcript |
mRNA
|
Organism |
Homo sapiens
|
Length |
3653 nt
|
Map |
17q23-q24
|
Location |
Chromosome 17 (NC_000017.10) strand : +
66508109...66508282 | 66511534...66511716 | 66518896...66519066 | 66519865...66519956 |
66520156...66520217 | 66521052...66521098 | 66521894...66522052 | 66523980...66524040 |
66525010...66525131 | 66526060...66526141 | 66526417...66528910 |
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Exon(s) |
Start |
End |
Length |
is coding |
Exon 1
|
1
|
174
|
174
|
1
|
Exon 3
|
175
|
357
|
183
|
1
|
Exon 4
|
358
|
528
|
171
|
1
|
Exon 5
|
529
|
620
|
92
|
1
|
Exon 6
|
621
|
682
|
62
|
1
|
Exon 7
|
683
|
729
|
47
|
1
|
Exon 8
|
730
|
888
|
159
|
1
|
Exon 9
|
889
|
949
|
61
|
1
|
Exon 10
|
950
|
1071
|
122
|
1
|
Exon 11
|
1072
|
1153
|
82
|
1
|
Exon 12
|
1154
|
3647
|
2494
|
1
|
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ID |
Class |
Location |
Mutation |
Length |
is synonymous |
Source |
rs8080306
|
SNP
|
134
|
a/c
|
1
|
?
|
dbSNP
|
|
|
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|
Primary source |
NCBI : CCDS11678
|
Nucleotide |
PRKAR1A, mRNA isoform 2[NM_212471.1] : 181...1326
|
Length |
1146
|
Location |
Chromosome 17 (NC_000017.10) strand : +
66511540...66511716 | 66518896...66519066 | 66519865...66519956 | 66520156...66520217 |
66521052...66521098 | 66521894...66522052 | 66523980...66524040 | 66525010...66525131 |
66526060...66526141 | 66526417...66526589 |
|
Start codon |
1
|
Translation |
NP_997636.1 |
|
|
|
|
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|
|
|
1 |
AGGGAGGGGG |
TGGAAAGGAG |
GGAGAAAAGG |
CAGAGGCGTC |
AAGGGAGGCC |
GGAGGGAGAG |
TGGGGTGGAC |
AGAGGAGCGG |
|
81 |
AGGGACGAGA |
GGGAAGCGCA |
CGATAGCTGC |
GCGGAGAGAG |
AGCGAAGAGC |
AGGCGGAGGA |
ACAAAGGCGA |
CCCAAGACAC |
|
161 |
CCAGAGAGGG |
ACAGAGAACC |
ATGGAGTCTG |
GCAGTACCGC |
CGCCAGTGAG |
GAGGCACGCA |
GCCTTCGAGA |
ATGTGAGCTC |
|
241 |
TACGTCCAGA |
AGCATAACAT |
TCAAGCGCTG |
CTCAAAGATT |
CTATTGTGCA |
GTTGTGCACT |
GCTCGACCTG |
AGAGACCCAT |
|
321 |
GGCATTCCTC |
AGGGAATACT |
TTGAGAGGTT |
GGAGAAGGAG |
GAGGCAAAAC |
AGATTCAGAA |
TCTGCAGAAA |
GCAGGCACTC |
|
401 |
GTACAGACTC |
AAGGGAGGAT |
GAGATTTCTC |
CTCCTCCACC |
CAACCCAGTG |
GTTAAAGGTA |
GGAGGCGACG |
AGGTGCTATC |
|
481 |
AGCGCTGAGG |
TCTACACGGA |
GGAAGATGCG |
GCATCCTATG |
TTAGAAAGGT |
TATACCAAAA |
GATTACAAGA |
CAATGGCCGC |
|
561 |
TTTAGCCAAA |
GCCATTGAAA |
AGAATGTGCT |
GTTTTCACAT |
CTTGATGATA |
ATGAGAGAAG |
TGATATTTTT |
GATGCCATGT |
|
641 |
TTTCGGTCTC |
CTTTATCGCA |
GGAGAGACTG |
TGATTCAGCA |
AGGTGATGAA |
GGGGATAACT |
TCTATGTGAT |
TGATCAAGGA |
|
721 |
GAGACGGATG |
TCTATGTTAA |
CAATGAATGG |
GCAACCAGTG |
TTGGGGAAGG |
AGGGAGCTTT |
GGAGAACTTG |
CTTTGATTTA |
|
801 |
TGGAACACCG |
AGAGCAGCCA |
CTGTCAAAGC |
AAAGACAAAT |
GTGAAATTGT |
GGGGCATCGA |
CCGAGACAGC |
TATAGAAGAA |
|
881 |
TCCTCATGGG |
AAGCACACTG |
AGAAAGCGGA |
AGATGTATGA |
GGAATTCCTT |
AGTAAAGTCT |
CTATTTTAGA |
GTCTCTGGAC |
|
961 |
AAGTGGGAAC |
GTCTTACGGT |
AGCTGATGCA |
TTGGAACCAG |
TGCAGTTTGA |
AGATGGGCAG |
AAGATTGTGG |
TGCAGGGAGA |
|
1041 |
ACCAGGGGAT |
GAGTTCTTCA |
TTATTTTAGA |
GGGGTCAGCT |
GCTGTGCTAC |
AACGTCGGTC |
AGAAAATGAA |
GAGTTTGTTG |
|
1121 |
AAGTGGGAAG |
ATTGGGGCCT |
TCTGATTATT |
TTGGTGAAAT |
TGCACTACTG |
ATGAATCGTC |
CTCGTGCTGC |
CACAGTTGTT |
|
1201 |
GCTCGTGGCC |
CCTTGAAGTG |
CGTTAAGCTG |
GACCGACCTA |
GATTTGAACG |
TGTTCTTGGC |
CCATGCTCAG |
ACATCCTCAA |
|
1281 |
ACGAAACATC |
CAGCAGTACA |
ACAGTTTTGT |
GTCACTGTCT |
GTCTGAAATC |
TGCCTCCTGT |
GCCTCCCTTT |
TCTCCTCTCC |
|
1361 |
CCAATCCATG |
CTTCACTCAT |
GCAAACTGCT |
TTATTTTCCC |
TACTTGCAGC |
GCCAAGTGGC |
CACTGGCATC |
GCAGCTTCCT |
|
1441 |
GTCTGTTTAT |
ATATTGAAAG |
TTGCTTTTAT |
TGCACCATTT |
TCAATTTGGA |
GCATTAACTA |
AATGCTCATA |
CACAGTTAAA |
|
1521 |
TAAATAGAAA |
GAGTTCTATG |
GAGACTTTGC |
TGTTACTGCT |
TCTCTTTGTG |
CAGTGTTAGT |
ATTCACCCTG |
GGCAGTGAGT |
|
1601 |
GCCATGCTTT |
TTGGTGAGGG |
CAGATCCCAG |
CACCTATTGA |
ATTACCATAG |
AGTAATGATG |
TAACAGTGCA |
AGATTTTTTT |
|
1681 |
TTTAAGTGAC |
ATAATTGTCC |
AGTTATAAGC |
GTATTTAGAC |
TGTGGCCATA |
TATGCTGTAT |
TTCTTTGTAG |
AATAAATGGT |
|
1761 |
TTCTCATTAA |
ACTCTAAAGA |
TTAGGGAAAA |
TGGATATAGA |
AAATCTTAGT |
ATAGTAGAAA |
GACATCTGCC |
TGTAATTAAA |
|
1841 |
CTAGTTTAAG |
GGTGGAAAAA |
TGCCCATTTT |
TGCTAATTAT |
CAATGGGATA |
TGATTGGTTC |
AGTTTTTTTT |
TTTCCAGAGT |
|
1921 |
TGTTGTTTGC |
CAAGCTAATC |
TGCCTGGTTT |
TATTTATATC |
TTGTTATTAA |
TGTTTCTTCT |
CCAATTCTGA |
AATACTTTTG |
|
2001 |
AGTATGGCTA |
TCTATACCTG |
CCTTTTAAGT |
TTGAAACTAA |
CTCATAGATT |
GCAAATATTG |
GTTAGTATTT |
AACTACATCT |
|
2081 |
GCCTCGGCTC |
ACAAATTCCG |
ATTAGACCTT |
TATCCAGCTA |
GTGCCAAATA |
ATTGATCAGA |
TGCTGAATTG |
AGAATAAGAA |
|
2161 |
TTTGAGGTCT |
ACATTCTTGG |
TTGTTAATTT |
AGAGCGTTTG |
GTTAAAGTAT |
GTCCTTCAGC |
TGACTCCAGT |
ATAATCTCCT |
|
2241 |
CTGCTCATTA |
AACTGATTCC |
AGGAGATTGG |
ATTTGCTGTG |
ACTAGATACA |
GATGGAGCAA |
ATGTCCTAAC |
AGAGAAATAG |
|
2321 |
AGGTGATGCT |
GCTAAAGGGA |
GAAATGCCAG |
GCGGACAAAG |
TTCAGTGTCG |
GGAATTTTCC |
CCGTGACATT |
CACTGGGGCA |
|
2401 |
TGAGATTTTG |
GAAGAAGTTT |
TTTACTTTGG |
TTTAGTCTTT |
TTTTCCTTCC |
TTTTTATTCA |
GCTAGAATTT |
CTGGTGGGTT |
|
2481 |
GATGGTAGGG |
TATAATGTGT |
CTGTGTTGCT |
TCAAATTGGT |
CTGAAAGGCT |
ATCCTGCTGA |
AAGTCCTGCT |
TTCCTATCTA |
|
2561 |
GCATTTATTT |
CTCTGGCAAA |
CTTTTCTTTC |
TTTTCTTTTT |
TAAAGTAAAC |
TTGTGTATTG |
AGTCTTAACT |
GTATTTCAGT |
|
2641 |
ATTTTCCAGC |
CTTATGTGTT |
ACATTATTCC |
AATGATACCC |
AACAGTTTAT |
TTTTATTATT |
TTTTTAAACA |
AAATTTCACA |
|
2721 |
GTTCTGTAAT |
GTAGGCACTT |
TTATTTTCAT |
TGTGATTTAT |
ATATAAGGTA |
ATGTAGGGTT |
ATATTTGGGA |
GTGACTGCAA |
|
2801 |
GCATTTTTCC |
ATCTGTGTGC |
AACTAACTGA |
CTCTGTTATT |
GATCCCTTCT |
CCTGCCCTTT |
CCCAGGTAAT |
TTAAATTGGT |
|
2881 |
CATGGTAGAT |
TTTTTTCATA |
GATTTGAAAA |
ACTTTTAGGT |
TGTTACCAAG |
TATGAAGTAT |
AAATCTGGGG |
AAGAGGTTTT |
|
2961 |
ATTTACATTT |
TAGGGTGGGT |
AAGAAAGCCA |
CCTTGTTACA |
AATTTTTTAA |
TTTCCAAAAT |
AATCTATATT |
AAATGAGGGT |
|
3041 |
TTCTGATCTG |
TACTTTGTGT |
TTAGCTACCT |
TTTTATATTT |
AAAAAATTAA |
AAATGAAAAT |
TACGTTCTTA |
CAAGCTTAAA |
|
3121 |
GCTTGATTTG |
ATCTTTGTTT |
AAATGCCAAA |
ATGTACTTAA |
ATGAGTTACT |
TAGAATGCCA |
TAAAATTGCA |
GTTTCATGTA |
|
3201 |
TGTATATAAT |
CATGCTCATG |
TATATTTAGT |
TACGTATAAT |
GCTTTCTGAG |
TGAGTTTTAC |
TCTTAAATCA |
TTTGGTTAAA |
|
3281 |
TCATTTGGCT |
TGCTGTTTAC |
TCCCTTCTGT |
AGTTTTTAAT |
TAAAAACTTT |
AAAGATAAGT |
CTACATTAAA |
CAATGATCAC |
|
3361 |
ATCTAAAGCT |
TTATCTTTGT |
GTAATCTAAG |
TATATGTGAG |
AAATCAGAAT |
TGGCATAATT |
TGTCTTAGTT |
GATATTCAAG |
|
3441 |
GCTTTAAAAG |
TCATTATTCC |
TGGGCTTGGT |
AAGTGAATTT |
ATGAGATTTA |
CTGCTCTAGA |
AAGTATAGAT |
GGCCAAAGGA |
|
3521 |
CCGTTTTGTA |
TTGCTTCCTG |
ATTACCAGTC |
TGATTATACC |
ATGTGTGCTA |
ATATACTTTT |
TTTGTTATAG |
ATTGTCTTAA |
|
3601 |
TGGTAGGTCA |
AGTAATAAAA |
AGAGATGAAA |
TAATTTAAAT |
TCTTAAAAAA |
AAA |
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>gi|47132580|ref|NM_212471.1|Protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) (PRKAR1A), transcript variant 2
AGGGAGGGGGTGGAAAGGAGGGAGAAAAGGCAGAGGCGTCAAGGGAGGCCGGAGGGAGAGTGGGGTGGACAGAGGAGCGG
AGGGACGAGAGGGAAGCGCACGATAGCTGCGCGGAGAGAGAGCGAAGAGCAGGCGGAGGAACAAAGGCGACCCAAGACAC
CCAGAGAGGGACAGAGAACCATGGAGTCTGGCAGTACCGCCGCCAGTGAGGAGGCACGCAGCCTTCGAGAATGTGAGCTC
TACGTCCAGAAGCATAACATTCAAGCGCTGCTCAAAGATTCTATTGTGCAGTTGTGCACTGCTCGACCTGAGAGACCCAT
GGCATTCCTCAGGGAATACTTTGAGAGGTTGGAGAAGGAGGAGGCAAAACAGATTCAGAATCTGCAGAAAGCAGGCACTC
GTACAGACTCAAGGGAGGATGAGATTTCTCCTCCTCCACCCAACCCAGTGGTTAAAGGTAGGAGGCGACGAGGTGCTATC
AGCGCTGAGGTCTACACGGAGGAAGATGCGGCATCCTATGTTAGAAAGGTTATACCAAAAGATTACAAGACAATGGCCGC
TTTAGCCAAAGCCATTGAAAAGAATGTGCTGTTTTCACATCTTGATGATAATGAGAGAAGTGATATTTTTGATGCCATGT
TTTCGGTCTCCTTTATCGCAGGAGAGACTGTGATTCAGCAAGGTGATGAAGGGGATAACTTCTATGTGATTGATCAAGGA
GAGACGGATGTCTATGTTAACAATGAATGGGCAACCAGTGTTGGGGAAGGAGGGAGCTTTGGAGAACTTGCTTTGATTTA
TGGAACACCGAGAGCAGCCACTGTCAAAGCAAAGACAAATGTGAAATTGTGGGGCATCGACCGAGACAGCTATAGAAGAA
TCCTCATGGGAAGCACACTGAGAAAGCGGAAGATGTATGAGGAATTCCTTAGTAAAGTCTCTATTTTAGAGTCTCTGGAC
AAGTGGGAACGTCTTACGGTAGCTGATGCATTGGAACCAGTGCAGTTTGAAGATGGGCAGAAGATTGTGGTGCAGGGAGA
ACCAGGGGATGAGTTCTTCATTATTTTAGAGGGGTCAGCTGCTGTGCTACAACGTCGGTCAGAAAATGAAGAGTTTGTTG
AAGTGGGAAGATTGGGGCCTTCTGATTATTTTGGTGAAATTGCACTACTGATGAATCGTCCTCGTGCTGCCACAGTTGTT
GCTCGTGGCCCCTTGAAGTGCGTTAAGCTGGACCGACCTAGATTTGAACGTGTTCTTGGCCCATGCTCAGACATCCTCAA
ACGAAACATCCAGCAGTACAACAGTTTTGTGTCACTGTCTGTCTGAAATCTGCCTCCTGTGCCTCCCTTTTCTCCTCTCC
CCAATCCATGCTTCACTCATGCAAACTGCTTTATTTTCCCTACTTGCAGCGCCAAGTGGCCACTGGCATCGCAGCTTCCT
GTCTGTTTATATATTGAAAGTTGCTTTTATTGCACCATTTTCAATTTGGAGCATTAACTAAATGCTCATACACAGTTAAA
TAAATAGAAAGAGTTCTATGGAGACTTTGCTGTTACTGCTTCTCTTTGTGCAGTGTTAGTATTCACCCTGGGCAGTGAGT
GCCATGCTTTTTGGTGAGGGCAGATCCCAGCACCTATTGAATTACCATAGAGTAATGATGTAACAGTGCAAGATTTTTTT
TTTAAGTGACATAATTGTCCAGTTATAAGCGTATTTAGACTGTGGCCATATATGCTGTATTTCTTTGTAGAATAAATGGT
TTCTCATTAAACTCTAAAGATTAGGGAAAATGGATATAGAAAATCTTAGTATAGTAGAAAGACATCTGCCTGTAATTAAA
CTAGTTTAAGGGTGGAAAAATGCCCATTTTTGCTAATTATCAATGGGATATGATTGGTTCAGTTTTTTTTTTTCCAGAGT
TGTTGTTTGCCAAGCTAATCTGCCTGGTTTTATTTATATCTTGTTATTAATGTTTCTTCTCCAATTCTGAAATACTTTTG
AGTATGGCTATCTATACCTGCCTTTTAAGTTTGAAACTAACTCATAGATTGCAAATATTGGTTAGTATTTAACTACATCT
GCCTCGGCTCACAAATTCCGATTAGACCTTTATCCAGCTAGTGCCAAATAATTGATCAGATGCTGAATTGAGAATAAGAA
TTTGAGGTCTACATTCTTGGTTGTTAATTTAGAGCGTTTGGTTAAAGTATGTCCTTCAGCTGACTCCAGTATAATCTCCT
CTGCTCATTAAACTGATTCCAGGAGATTGGATTTGCTGTGACTAGATACAGATGGAGCAAATGTCCTAACAGAGAAATAG
AGGTGATGCTGCTAAAGGGAGAAATGCCAGGCGGACAAAGTTCAGTGTCGGGAATTTTCCCCGTGACATTCACTGGGGCA
TGAGATTTTGGAAGAAGTTTTTTACTTTGGTTTAGTCTTTTTTTCCTTCCTTTTTATTCAGCTAGAATTTCTGGTGGGTT
GATGGTAGGGTATAATGTGTCTGTGTTGCTTCAAATTGGTCTGAAAGGCTATCCTGCTGAAAGTCCTGCTTTCCTATCTA
GCATTTATTTCTCTGGCAAACTTTTCTTTCTTTTCTTTTTTAAAGTAAACTTGTGTATTGAGTCTTAACTGTATTTCAGT
ATTTTCCAGCCTTATGTGTTACATTATTCCAATGATACCCAACAGTTTATTTTTATTATTTTTTTAAACAAAATTTCACA
GTTCTGTAATGTAGGCACTTTTATTTTCATTGTGATTTATATATAAGGTAATGTAGGGTTATATTTGGGAGTGACTGCAA
GCATTTTTCCATCTGTGTGCAACTAACTGACTCTGTTATTGATCCCTTCTCCTGCCCTTTCCCAGGTAATTTAAATTGGT
CATGGTAGATTTTTTTCATAGATTTGAAAAACTTTTAGGTTGTTACCAAGTATGAAGTATAAATCTGGGGAAGAGGTTTT
ATTTACATTTTAGGGTGGGTAAGAAAGCCACCTTGTTACAAATTTTTTAATTTCCAAAATAATCTATATTAAATGAGGGT
TTCTGATCTGTACTTTGTGTTTAGCTACCTTTTTATATTTAAAAAATTAAAAATGAAAATTACGTTCTTACAAGCTTAAA
GCTTGATTTGATCTTTGTTTAAATGCCAAAATGTACTTAAATGAGTTACTTAGAATGCCATAAAATTGCAGTTTCATGTA
TGTATATAATCATGCTCATGTATATTTAGTTACGTATAATGCTTTCTGAGTGAGTTTTACTCTTAAATCATTTGGTTAAA
TCATTTGGCTTGCTGTTTACTCCCTTCTGTAGTTTTTAATTAAAAACTTTAAAGATAAGTCTACATTAAACAATGATCAC
ATCTAAAGCTTTATCTTTGTGTAATCTAAGTATATGTGAGAAATCAGAATTGGCATAATTTGTCTTAGTTGATATTCAAG
GCTTTAAAAGTCATTATTCCTGGGCTTGGTAAGTGAATTTATGAGATTTACTGCTCTAGAAAGTATAGATGGCCAAAGGA
CCGTTTTGTATTGCTTCCTGATTACCAGTCTGATTATACCATGTGTGCTAATATACTTTTTTTGTTATAGATTGTCTTAA
TGGTAGGTCAAGTAATAAAAAGAGATGAAATAATTTAAATTCTTAAAAAAAAA
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Primary source |
RefSeq : NM_212472.1 (GI:47132582)
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Name |
Protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) (PRKAR1A), transcript variant 3
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Type of transcript |
mRNA
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Organism |
Homo sapiens
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Length |
3657 nt
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Map |
17q23-q24
|
Location |
Chromosome 17 (NC_000017.10) strand : +
66508542...66508719 | 66511534...66511716 | 66518896...66519066 | 66519865...66519956 |
66520156...66520217 | 66521052...66521098 | 66521894...66522052 | 66523980...66524040 |
66525010...66525131 | 66526060...66526141 | 66526417...66528910 |
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Exon(s) |
Start |
End |
Length |
is coding |
Exon 2b
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1
|
178
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178
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1
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Exon 3
|
179
|
361
|
183
|
1
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Exon 4
|
362
|
532
|
171
|
1
|
Exon 5
|
533
|
624
|
92
|
1
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Exon 6
|
625
|
686
|
62
|
1
|
Exon 7
|
687
|
733
|
47
|
1
|
Exon 8
|
734
|
892
|
159
|
1
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Exon 9
|
893
|
953
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61
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1
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Exon 10
|
954
|
1075
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122
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1
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Exon 11
|
1076
|
1157
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82
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1
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Exon 12
|
1158
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3651
|
2494
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1
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ID |
Class |
Location |
Mutation |
Length |
is synonymous |
Source |
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Primary source |
NCBI : CCDS11678
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Nucleotide |
PRKAR1A, mRNA isoform 3[NM_212472.1] : 185...1330
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Length |
1146
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Location |
Chromosome 17 (NC_000017.10) strand : +
66511540...66511716 | 66518896...66519066 | 66519865...66519956 | 66520156...66520217 |
66521052...66521098 | 66521894...66522052 | 66523980...66524040 | 66525010...66525131 |
66526060...66526141 | 66526417...66526589 |
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Start codon |
1
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Translation |
NP_997637.1 |
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1 |
GATTGGCTGC |
GGCCAGGCCG |
TTTCCGGTGG |
AGCTGTCGCC |
TAGCCGCTAT |
CGCAGAGTGG |
AGCGGGGCTG |
GGAGCAAAGC |
|
81 |
GCTGAGGGAG |
CTCGGTACGC |
CGCCGCCTCG |
CACCCGCAGC |
CTCGCGCCCG |
CCGCCGCCCG |
TCCCCAGGTG |
AGTGGGGTCG |
|
161 |
GCCGGGGGCT |
CAGGCGAGAG |
AACCATGGAG |
TCTGGCAGTA |
CCGCCGCCAG |
TGAGGAGGCA |
CGCAGCCTTC |
GAGAATGTGA |
|
241 |
GCTCTACGTC |
CAGAAGCATA |
ACATTCAAGC |
GCTGCTCAAA |
GATTCTATTG |
TGCAGTTGTG |
CACTGCTCGA |
CCTGAGAGAC |
|
321 |
CCATGGCATT |
CCTCAGGGAA |
TACTTTGAGA |
GGTTGGAGAA |
GGAGGAGGCA |
AAACAGATTC |
AGAATCTGCA |
GAAAGCAGGC |
|
401 |
ACTCGTACAG |
ACTCAAGGGA |
GGATGAGATT |
TCTCCTCCTC |
CACCCAACCC |
AGTGGTTAAA |
GGTAGGAGGC |
GACGAGGTGC |
|
481 |
TATCAGCGCT |
GAGGTCTACA |
CGGAGGAAGA |
TGCGGCATCC |
TATGTTAGAA |
AGGTTATACC |
AAAAGATTAC |
AAGACAATGG |
|
561 |
CCGCTTTAGC |
CAAAGCCATT |
GAAAAGAATG |
TGCTGTTTTC |
ACATCTTGAT |
GATAATGAGA |
GAAGTGATAT |
TTTTGATGCC |
|
641 |
ATGTTTTCGG |
TCTCCTTTAT |
CGCAGGAGAG |
ACTGTGATTC |
AGCAAGGTGA |
TGAAGGGGAT |
AACTTCTATG |
TGATTGATCA |
|
721 |
AGGAGAGACG |
GATGTCTATG |
TTAACAATGA |
ATGGGCAACC |
AGTGTTGGGG |
AAGGAGGGAG |
CTTTGGAGAA |
CTTGCTTTGA |
|
801 |
TTTATGGAAC |
ACCGAGAGCA |
GCCACTGTCA |
AAGCAAAGAC |
AAATGTGAAA |
TTGTGGGGCA |
TCGACCGAGA |
CAGCTATAGA |
|
881 |
AGAATCCTCA |
TGGGAAGCAC |
ACTGAGAAAG |
CGGAAGATGT |
ATGAGGAATT |
CCTTAGTAAA |
GTCTCTATTT |
TAGAGTCTCT |
|
961 |
GGACAAGTGG |
GAACGTCTTA |
CGGTAGCTGA |
TGCATTGGAA |
CCAGTGCAGT |
TTGAAGATGG |
GCAGAAGATT |
GTGGTGCAGG |
|
1041 |
GAGAACCAGG |
GGATGAGTTC |
TTCATTATTT |
TAGAGGGGTC |
AGCTGCTGTG |
CTACAACGTC |
GGTCAGAAAA |
TGAAGAGTTT |
|
1121 |
GTTGAAGTGG |
GAAGATTGGG |
GCCTTCTGAT |
TATTTTGGTG |
AAATTGCACT |
ACTGATGAAT |
CGTCCTCGTG |
CTGCCACAGT |
|
1201 |
TGTTGCTCGT |
GGCCCCTTGA |
AGTGCGTTAA |
GCTGGACCGA |
CCTAGATTTG |
AACGTGTTCT |
TGGCCCATGC |
TCAGACATCC |
|
1281 |
TCAAACGAAA |
CATCCAGCAG |
TACAACAGTT |
TTGTGTCACT |
GTCTGTCTGA |
AATCTGCCTC |
CTGTGCCTCC |
CTTTTCTCCT |
|
1361 |
CTCCCCAATC |
CATGCTTCAC |
TCATGCAAAC |
TGCTTTATTT |
TCCCTACTTG |
CAGCGCCAAG |
TGGCCACTGG |
CATCGCAGCT |
|
1441 |
TCCTGTCTGT |
TTATATATTG |
AAAGTTGCTT |
TTATTGCACC |
ATTTTCAATT |
TGGAGCATTA |
ACTAAATGCT |
CATACACAGT |
|
1521 |
TAAATAAATA |
GAAAGAGTTC |
TATGGAGACT |
TTGCTGTTAC |
TGCTTCTCTT |
TGTGCAGTGT |
TAGTATTCAC |
CCTGGGCAGT |
|
1601 |
GAGTGCCATG |
CTTTTTGGTG |
AGGGCAGATC |
CCAGCACCTA |
TTGAATTACC |
ATAGAGTAAT |
GATGTAACAG |
TGCAAGATTT |
|
1681 |
TTTTTTTAAG |
TGACATAATT |
GTCCAGTTAT |
AAGCGTATTT |
AGACTGTGGC |
CATATATGCT |
GTATTTCTTT |
GTAGAATAAA |
|
1761 |
TGGTTTCTCA |
TTAAACTCTA |
AAGATTAGGG |
AAAATGGATA |
TAGAAAATCT |
TAGTATAGTA |
GAAAGACATC |
TGCCTGTAAT |
|
1841 |
TAAACTAGTT |
TAAGGGTGGA |
AAAATGCCCA |
TTTTTGCTAA |
TTATCAATGG |
GATATGATTG |
GTTCAGTTTT |
TTTTTTTCCA |
|
1921 |
GAGTTGTTGT |
TTGCCAAGCT |
AATCTGCCTG |
GTTTTATTTA |
TATCTTGTTA |
TTAATGTTTC |
TTCTCCAATT |
CTGAAATACT |
|
2001 |
TTTGAGTATG |
GCTATCTATA |
CCTGCCTTTT |
AAGTTTGAAA |
CTAACTCATA |
GATTGCAAAT |
ATTGGTTAGT |
ATTTAACTAC |
|
2081 |
ATCTGCCTCG |
GCTCACAAAT |
TCCGATTAGA |
CCTTTATCCA |
GCTAGTGCCA |
AATAATTGAT |
CAGATGCTGA |
ATTGAGAATA |
|
2161 |
AGAATTTGAG |
GTCTACATTC |
TTGGTTGTTA |
ATTTAGAGCG |
TTTGGTTAAA |
GTATGTCCTT |
CAGCTGACTC |
CAGTATAATC |
|
2241 |
TCCTCTGCTC |
ATTAAACTGA |
TTCCAGGAGA |
TTGGATTTGC |
TGTGACTAGA |
TACAGATGGA |
GCAAATGTCC |
TAACAGAGAA |
|
2321 |
ATAGAGGTGA |
TGCTGCTAAA |
GGGAGAAATG |
CCAGGCGGAC |
AAAGTTCAGT |
GTCGGGAATT |
TTCCCCGTGA |
CATTCACTGG |
|
2401 |
GGCATGAGAT |
TTTGGAAGAA |
GTTTTTTACT |
TTGGTTTAGT |
CTTTTTTTCC |
TTCCTTTTTA |
TTCAGCTAGA |
ATTTCTGGTG |
|
2481 |
GGTTGATGGT |
AGGGTATAAT |
GTGTCTGTGT |
TGCTTCAAAT |
TGGTCTGAAA |
GGCTATCCTG |
CTGAAAGTCC |
TGCTTTCCTA |
|
2561 |
TCTAGCATTT |
ATTTCTCTGG |
CAAACTTTTC |
TTTCTTTTCT |
TTTTTAAAGT |
AAACTTGTGT |
ATTGAGTCTT |
AACTGTATTT |
|
2641 |
CAGTATTTTC |
CAGCCTTATG |
TGTTACATTA |
TTCCAATGAT |
ACCCAACAGT |
TTATTTTTAT |
TATTTTTTTA |
AACAAAATTT |
|
2721 |
CACAGTTCTG |
TAATGTAGGC |
ACTTTTATTT |
TCATTGTGAT |
TTATATATAA |
GGTAATGTAG |
GGTTATATTT |
GGGAGTGACT |
|
2801 |
GCAAGCATTT |
TTCCATCTGT |
GTGCAACTAA |
CTGACTCTGT |
TATTGATCCC |
TTCTCCTGCC |
CTTTCCCAGG |
TAATTTAAAT |
|
2881 |
TGGTCATGGT |
AGATTTTTTT |
CATAGATTTG |
AAAAACTTTT |
AGGTTGTTAC |
CAAGTATGAA |
GTATAAATCT |
GGGGAAGAGG |
|
2961 |
TTTTATTTAC |
ATTTTAGGGT |
GGGTAAGAAA |
GCCACCTTGT |
TACAAATTTT |
TTAATTTCCA |
AAATAATCTA |
TATTAAATGA |
|
3041 |
GGGTTTCTGA |
TCTGTACTTT |
GTGTTTAGCT |
ACCTTTTTAT |
ATTTAAAAAA |
TTAAAAATGA |
AAATTACGTT |
CTTACAAGCT |
|
3121 |
TAAAGCTTGA |
TTTGATCTTT |
GTTTAAATGC |
CAAAATGTAC |
TTAAATGAGT |
TACTTAGAAT |
GCCATAAAAT |
TGCAGTTTCA |
|
3201 |
TGTATGTATA |
TAATCATGCT |
CATGTATATT |
TAGTTACGTA |
TAATGCTTTC |
TGAGTGAGTT |
TTACTCTTAA |
ATCATTTGGT |
|
3281 |
TAAATCATTT |
GGCTTGCTGT |
TTACTCCCTT |
CTGTAGTTTT |
TAATTAAAAA |
CTTTAAAGAT |
AAGTCTACAT |
TAAACAATGA |
|
3361 |
TCACATCTAA |
AGCTTTATCT |
TTGTGTAATC |
TAAGTATATG |
TGAGAAATCA |
GAATTGGCAT |
AATTTGTCTT |
AGTTGATATT |
|
3441 |
CAAGGCTTTA |
AAAGTCATTA |
TTCCTGGGCT |
TGGTAAGTGA |
ATTTATGAGA |
TTTACTGCTC |
TAGAAAGTAT |
AGATGGCCAA |
|
3521 |
AGGACCGTTT |
TGTATTGCTT |
CCTGATTACC |
AGTCTGATTA |
TACCATGTGT |
GCTAATATAC |
TTTTTTTGTT |
ATAGATTGTC |
|
3601 |
TTAATGGTAG |
GTCAAGTAAT |
AAAAAGAGAT |
GAAATAATTT |
AAATTCTTAA |
AAAAAAA |
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>gi|47132582|ref|NM_212472.1|Protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) (PRKAR1A), transcript variant 3
GATTGGCTGCGGCCAGGCCGTTTCCGGTGGAGCTGTCGCCTAGCCGCTATCGCAGAGTGGAGCGGGGCTGGGAGCAAAGC
GCTGAGGGAGCTCGGTACGCCGCCGCCTCGCACCCGCAGCCTCGCGCCCGCCGCCGCCCGTCCCCAGGTGAGTGGGGTCG
GCCGGGGGCTCAGGCGAGAGAACCATGGAGTCTGGCAGTACCGCCGCCAGTGAGGAGGCACGCAGCCTTCGAGAATGTGA
GCTCTACGTCCAGAAGCATAACATTCAAGCGCTGCTCAAAGATTCTATTGTGCAGTTGTGCACTGCTCGACCTGAGAGAC
CCATGGCATTCCTCAGGGAATACTTTGAGAGGTTGGAGAAGGAGGAGGCAAAACAGATTCAGAATCTGCAGAAAGCAGGC
ACTCGTACAGACTCAAGGGAGGATGAGATTTCTCCTCCTCCACCCAACCCAGTGGTTAAAGGTAGGAGGCGACGAGGTGC
TATCAGCGCTGAGGTCTACACGGAGGAAGATGCGGCATCCTATGTTAGAAAGGTTATACCAAAAGATTACAAGACAATGG
CCGCTTTAGCCAAAGCCATTGAAAAGAATGTGCTGTTTTCACATCTTGATGATAATGAGAGAAGTGATATTTTTGATGCC
ATGTTTTCGGTCTCCTTTATCGCAGGAGAGACTGTGATTCAGCAAGGTGATGAAGGGGATAACTTCTATGTGATTGATCA
AGGAGAGACGGATGTCTATGTTAACAATGAATGGGCAACCAGTGTTGGGGAAGGAGGGAGCTTTGGAGAACTTGCTTTGA
TTTATGGAACACCGAGAGCAGCCACTGTCAAAGCAAAGACAAATGTGAAATTGTGGGGCATCGACCGAGACAGCTATAGA
AGAATCCTCATGGGAAGCACACTGAGAAAGCGGAAGATGTATGAGGAATTCCTTAGTAAAGTCTCTATTTTAGAGTCTCT
GGACAAGTGGGAACGTCTTACGGTAGCTGATGCATTGGAACCAGTGCAGTTTGAAGATGGGCAGAAGATTGTGGTGCAGG
GAGAACCAGGGGATGAGTTCTTCATTATTTTAGAGGGGTCAGCTGCTGTGCTACAACGTCGGTCAGAAAATGAAGAGTTT
GTTGAAGTGGGAAGATTGGGGCCTTCTGATTATTTTGGTGAAATTGCACTACTGATGAATCGTCCTCGTGCTGCCACAGT
TGTTGCTCGTGGCCCCTTGAAGTGCGTTAAGCTGGACCGACCTAGATTTGAACGTGTTCTTGGCCCATGCTCAGACATCC
TCAAACGAAACATCCAGCAGTACAACAGTTTTGTGTCACTGTCTGTCTGAAATCTGCCTCCTGTGCCTCCCTTTTCTCCT
CTCCCCAATCCATGCTTCACTCATGCAAACTGCTTTATTTTCCCTACTTGCAGCGCCAAGTGGCCACTGGCATCGCAGCT
TCCTGTCTGTTTATATATTGAAAGTTGCTTTTATTGCACCATTTTCAATTTGGAGCATTAACTAAATGCTCATACACAGT
TAAATAAATAGAAAGAGTTCTATGGAGACTTTGCTGTTACTGCTTCTCTTTGTGCAGTGTTAGTATTCACCCTGGGCAGT
GAGTGCCATGCTTTTTGGTGAGGGCAGATCCCAGCACCTATTGAATTACCATAGAGTAATGATGTAACAGTGCAAGATTT
TTTTTTTAAGTGACATAATTGTCCAGTTATAAGCGTATTTAGACTGTGGCCATATATGCTGTATTTCTTTGTAGAATAAA
TGGTTTCTCATTAAACTCTAAAGATTAGGGAAAATGGATATAGAAAATCTTAGTATAGTAGAAAGACATCTGCCTGTAAT
TAAACTAGTTTAAGGGTGGAAAAATGCCCATTTTTGCTAATTATCAATGGGATATGATTGGTTCAGTTTTTTTTTTTCCA
GAGTTGTTGTTTGCCAAGCTAATCTGCCTGGTTTTATTTATATCTTGTTATTAATGTTTCTTCTCCAATTCTGAAATACT
TTTGAGTATGGCTATCTATACCTGCCTTTTAAGTTTGAAACTAACTCATAGATTGCAAATATTGGTTAGTATTTAACTAC
ATCTGCCTCGGCTCACAAATTCCGATTAGACCTTTATCCAGCTAGTGCCAAATAATTGATCAGATGCTGAATTGAGAATA
AGAATTTGAGGTCTACATTCTTGGTTGTTAATTTAGAGCGTTTGGTTAAAGTATGTCCTTCAGCTGACTCCAGTATAATC
TCCTCTGCTCATTAAACTGATTCCAGGAGATTGGATTTGCTGTGACTAGATACAGATGGAGCAAATGTCCTAACAGAGAA
ATAGAGGTGATGCTGCTAAAGGGAGAAATGCCAGGCGGACAAAGTTCAGTGTCGGGAATTTTCCCCGTGACATTCACTGG
GGCATGAGATTTTGGAAGAAGTTTTTTACTTTGGTTTAGTCTTTTTTTCCTTCCTTTTTATTCAGCTAGAATTTCTGGTG
GGTTGATGGTAGGGTATAATGTGTCTGTGTTGCTTCAAATTGGTCTGAAAGGCTATCCTGCTGAAAGTCCTGCTTTCCTA
TCTAGCATTTATTTCTCTGGCAAACTTTTCTTTCTTTTCTTTTTTAAAGTAAACTTGTGTATTGAGTCTTAACTGTATTT
CAGTATTTTCCAGCCTTATGTGTTACATTATTCCAATGATACCCAACAGTTTATTTTTATTATTTTTTTAAACAAAATTT
CACAGTTCTGTAATGTAGGCACTTTTATTTTCATTGTGATTTATATATAAGGTAATGTAGGGTTATATTTGGGAGTGACT
GCAAGCATTTTTCCATCTGTGTGCAACTAACTGACTCTGTTATTGATCCCTTCTCCTGCCCTTTCCCAGGTAATTTAAAT
TGGTCATGGTAGATTTTTTTCATAGATTTGAAAAACTTTTAGGTTGTTACCAAGTATGAAGTATAAATCTGGGGAAGAGG
TTTTATTTACATTTTAGGGTGGGTAAGAAAGCCACCTTGTTACAAATTTTTTAATTTCCAAAATAATCTATATTAAATGA
GGGTTTCTGATCTGTACTTTGTGTTTAGCTACCTTTTTATATTTAAAAAATTAAAAATGAAAATTACGTTCTTACAAGCT
TAAAGCTTGATTTGATCTTTGTTTAAATGCCAAAATGTACTTAAATGAGTTACTTAGAATGCCATAAAATTGCAGTTTCA
TGTATGTATATAATCATGCTCATGTATATTTAGTTACGTATAATGCTTTCTGAGTGAGTTTTACTCTTAAATCATTTGGT
TAAATCATTTGGCTTGCTGTTTACTCCCTTCTGTAGTTTTTAATTAAAAACTTTAAAGATAAGTCTACATTAAACAATGA
TCACATCTAAAGCTTTATCTTTGTGTAATCTAAGTATATGTGAGAAATCAGAATTGGCATAATTTGTCTTAGTTGATATT
CAAGGCTTTAAAAGTCATTATTCCTGGGCTTGGTAAGTGAATTTATGAGATTTACTGCTCTAGAAAGTATAGATGGCCAA
AGGACCGTTTTGTATTGCTTCCTGATTACCAGTCTGATTATACCATGTGTGCTAATATACTTTTTTTGTTATAGATTGTC
TTAATGGTAGGTCAAGTAATAAAAAGAGATGAAATAATTTAAATTCTTAAAAAAAAA
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Exon number |
1
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Length |
174 nt
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Location |
Chromosome 17 (NC_000017.10) : 66508109...66508282 (+)
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Is part of |
PRKAR1A, mRNA isoform 2
(NM_212471.1)
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Sequence |
Show
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AGGGAGGGGGTGGAAAGGAGGGAGAAAAGGCAGAGGCGTCAAGGGAGGCCGGAGGGAGAGTGGGGTGGACAGAGGAGCGG
AGGGACGAGAGGGAAGCGCACGATAGCTGCGCGGAGAGAGAGCGAAGAGCAGGCGGAGGAACAAAGGCGACCCAAGACAC
CCAGAGAGGGACAG
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Exon number |
2a
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Length |
147 nt
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Location |
Chromosome 17 (NC_000017.10) : 66508542...66508688 (+)
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Is part of |
PRKAR1A, mRNA isoform 1
(NM_002734.3)
|
Sequence |
Show
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GATTGGCTGCGGCCAGGCCGTTTCCGGTGGAGCTGTCGCCTAGCCGCTATCGCAGAGTGGAGCGGGGCTGGGAGCAAAGC
GCTGAGGGAGCTCGGTACGCCGCCGCCTCGCACCCGCAGCCTCGCGCCCGCCGCCGCCCGTCCCCAG
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Exon number |
2b
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Length |
178 nt
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Location |
Chromosome 17 (NC_000017.10) : 66508542...66508719 (+)
|
Is part of |
PRKAR1A, mRNA isoform 3
(NM_212472.1)
|
Sequence |
Show
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GATTGGCTGCGGCCAGGCCGTTTCCGGTGGAGCTGTCGCCTAGCCGCTATCGCAGAGTGGAGCGGGGCTGGGAGCAAAGC
GCTGAGGGAGCTCGGTACGCCGCCGCCTCGCACCCGCAGCCTCGCGCCCGCCGCCGCCCGTCCCCAGGTGAGTGGGGTCG
GCCGGGGGCTCAGGCGAG
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Exon number |
12
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Length |
2494 nt
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Location |
Chromosome 17 (NC_000017.10) : 66526417...66528910 (+)
|
Is part of |
PRKAR1A, mRNA isoform 1
(NM_002734.3)
PRKAR1A, mRNA isoform 3
(NM_212472.1)
PRKAR1A, mRNA isoform 2
(NM_212471.1)
|
Sequence |
Show
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GTGAAATTGCACTACTGATGAATCGTCCTCGTGCTGCCACAGTTGTTGCTCGTGGCCCCTTGAAGTGCGTTAAGCTGGAC
CGACCTAGATTTGAACGTGTTCTTGGCCCATGCTCAGACATCCTCAAACGAAACATCCAGCAGTACAACAGTTTTGTGTC
ACTGTCTGTCTGAAATCTGCCTCCTGTGCCTCCCTTTTCTCCTCTCCCCAATCCATGCTTCACTCATGCAAACTGCTTTA
TTTTCCCTACTTGCAGCGCCAAGTGGCCACTGGCATCGCAGCTTCCTGTCTGTTTATATATTGAAAGTTGCTTTTATTGC
ACCATTTTCAATTTGGAGCATTAACTAAATGCTCATACACAGTTAAATAAATAGAAAGAGTTCTATGGAGACTTTGCTGT
TACTGCTTCTCTTTGTGCAGTGTTAGTATTCACCCTGGGCAGTGAGTGCCATGCTTTTTGGTGAGGGCAGATCCCAGCAC
CTATTGAATTACCATAGAGTAATGATGTAACAGTGCAAGATTTTTTTTTTAAGTGACATAATTGTCCAGTTATAAGCGTA
TTTAGACTGTGGCCATATATGCTGTATTTCTTTGTAGAATAAATGGTTTCTCATTAAACTCTAAAGATTAGGGAAAATGG
ATATAGAAAATCTTAGTATAGTAGAAAGACATCTGCCTGTAATTAAACTAGTTTAAGGGTGGAAAAATGCCCATTTTTGC
TAATTATCAATGGGATATGATTGGTTCAGTTTTTTTTTTTCCAGAGTTGTTGTTTGCCAAGCTAATCTGCCTGGTTTTAT
TTATATCTTGTTATTAATGTTTCTTCTCCAATTCTGAAATACTTTTGAGTATGGCTATCTATACCTGCCTTTTAAGTTTG
AAACTAACTCATAGATTGCAAATATTGGTTAGTATTTAACTACATCTGCCTCGGCTCACAAATTCCGATTAGACCTTTAT
CCAGCTAGTGCCAAATAATTGATCAGATGCTGAATTGAGAATAAGAATTTGAGGTCTACATTCTTGGTTGTTAATTTAGA
GCGTTTGGTTAAAGTATGTCCTTCAGCTGACTCCAGTATAATCTCCTCTGCTCATTAAACTGATTCCAGGAGATTGGATT
TGCTGTGACTAGATACAGATGGAGCAAATGTCCTAACAGAGAAATAGAGGTGATGCTGCTAAAGGGAGAAATGCCAGGCG
GACAAAGTTCAGTGTCGGGAATTTTCCCCGTGACATTCACTGGGGCATGAGATTTTGGAAGAAGTTTTTTACTTTGGTTT
AGTCTTTTTTTCCTTCCTTTTTATTCAGCTAGAATTTCTGGTGGGTTGATGGTAGGGTATAATGTGTCTGTGTTGCTTCA
AATTGGTCTGAAAGGCTATCCTGCTGAAAGTCCTGCTTTCCTATCTAGCATTTATTTCTCTGGCAAACTTTTCTTTCTTT
TCTTTTTTAAAGTAAACTTGTGTATTGAGTCTTAACTGTATTTCAGTATTTTCCAGCCTTATGTGTTACATTATTCCAAT
GATACCCAACAGTTTATTTTTATTATTTTTTTAAACAAAATTTCACAGTTCTGTAATGTAGGCACTTTTATTTTCATTGT
GATTTATATATAAGGTAATGTAGGGTTATATTTGGGAGTGACTGCAAGCATTTTTCCATCTGTGTGCAACTAACTGACTC
TGTTATTGATCCCTTCTCCTGCCCTTTCCCAGGTAATTTAAATTGGTCATGGTAGATTTTTTTCATAGATTTGAAAAACT
TTTAGGTTGTTACCAAGTATGAAGTATAAATCTGGGGAAGAGGTTTTATTTACATTTTAGGGTGGGTAAGAAAGCCACCT
TGTTACAAATTTTTTAATTTCCAAAATAATCTATATTAAATGAGGGTTTCTGATCTGTACTTTGTGTTTAGCTACCTTTT
TATATTTAAAAAATTAAAAATGAAAATTACGTTCTTACAAGCTTAAAGCTTGATTTGATCTTTGTTTAAATGCCAAAATG
TACTTAAATGAGTTACTTAGAATGCCATAAAATTGCAGTTTCATGTATGTATATAATCATGCTCATGTATATTTAGTTAC
GTATAATGCTTTCTGAGTGAGTTTTACTCTTAAATCATTTGGTTAAATCATTTGGCTTGCTGTTTACTCCCTTCTGTAGT
TTTTAATTAAAAACTTTAAAGATAAGTCTACATTAAACAATGATCACATCTAAAGCTTTATCTTTGTGTAATCTAAGTAT
ATGTGAGAAATCAGAATTGGCATAATTTGTCTTAGTTGATATTCAAGGCTTTAAAAGTCATTATTCCTGGGCTTGGTAAG
TGAATTTATGAGATTTACTGCTCTAGAAAGTATAGATGGCCAAAGGACCGTTTTGTATTGCTTCCTGATTACCAGTCTGA
TTATACCATGTGTGCTAATATACTTTTTTTGTTATAGATTGTCTTAATGGTAGGTCAAGTAATAAAAAGAGATGAAATAA
TTTAAATTCTTAAA
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Primary source |
Uniprot : P10644
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Name |
cAMP-dependent protein kinase type I-alpha regulatory subunit
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Alternative name(s) |
Tissue-specific extinguisher 1
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Synonym(s) |
TSE1
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Organism |
Homo sapiens
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Length |
381 aa
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Protein existence |
---
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General annotation (Comments)
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Disease
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Defects in PRKAR1A are the cause of Carney complex type 1 (CNC1) [MIM:160980]. CNC is a multiple neoplasia syndrome characterized by spotty skin pigmentation, cardiac and other myxomas, endocrine tumors, and psammomatous melanotic schwannomas.
Defects in PRKAR1A are the cause of intracardiac myxoma [MIM:255960]. Inheritance is autosomal recessive.
Defects in PRKAR1A are the cause of primary pigmented nodular adrenocortical disease type 1 (PPNAD1) [MIM:610489]. Primary pigmented nodular adrenocortical disease is a rare bilateral adrenal defect causing ACTH-independent Cushing syndrome. Macroscopic appearance of the adrenals is characteristic with small pigmented micronodules observed in the cortex. PPNAD1 is most often diagnosed in patients with Carney complex, but it can also be observed in patients without other manifestations or familial history.
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Ptm
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The pseudophosphorylation site binds to the substrate-binding region of the catalytic chain, resulting in the inhibition of its activity.
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Similarity
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Belongs to the cAMP-dependent kinase regulatory chain family.
Contains 2 cyclic nucleotide-binding domains.
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Subunit
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The inactive form of the enzyme is composed of two regulatory chains and two catalytic chains. Activation by cAMP produces two active catalytic monomers and a regulatory dimer that binds four cAMP molecules. PRKAR1A also interacts with RFC2; the complex may be involved in cell survival. Interacts with AKAP4.
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Tissue specificity
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Four types of regulatory chains are found: I- alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.
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Biological process
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regulation of protein amino acid phosphorylation [GO:0001932]
regulation of transcription from RNA polymerase II promoter [GO:0006357]
signal transduction [GO:0007165]
hormone-mediated signaling pathway [GO:0009755]
intracellular signaling pathway [GO:0023034]
activation of protein kinase A activity [GO:0034199]
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Cellular component
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cytosol [GO:0005829]
cAMP-dependent protein kinase complex [GO:0005952]
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Molecular function
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protein binding [GO:0005515]
cAMP-dependent protein kinase regulator activity [GO:0008603]
cAMP binding [GO:0030552]
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With
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Uniprot accession
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IntAct
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SET
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Q01105
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EBI-476431,EBI-1053182
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SLC25A27
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O95847
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EBI-476431,EBI-2691027
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TUSC4
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Q8WTW4
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EBI-476431,
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PLEKHF2
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Q9H8W4
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EBI-476431,EBI-742388
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NUAK1
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O60285
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EBI-476431,
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UBE2M
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P61081
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EBI-476431,EBI-1041660
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TCEAL5
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Q5H9L2
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EBI-476431,EBI-2681773
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MCRS1
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Q96EZ8
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EBI-476431,
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AKAP10
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O43572
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EBI-476431,EBI-752153
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FTSJD2
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Q8N1G2
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EBI-476431,EBI-2691086
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C2orf88
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Q9BSF0
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EBI-476431,EBI-744298
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CRB1
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P82279
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EBI-476431,EBI-1048648
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PRKACA
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P17612
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EBI-476431,EBI-476586
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RFC2
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P35250
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EBI-476431,EBI-476409
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SPTBN1
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Q01082
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EBI-476431,EBI-351561
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ANP32B
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Q92688
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EBI-476431,EBI-762428
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Alternative product(s)
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Feature key |
Position
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Length
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Description
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Feature identifier
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Region |
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Motif
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96 - 100
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5
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Pseudophosphorylation motif
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P10644-MOTIF-96
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Nucleotide binding
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137 - 254
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118
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cAMP 1
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P10644-NP_BIND-137
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Nucleotide binding
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255 - 381
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127
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cAMP 2
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P10644-NP_BIND-255
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Region
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1 - 136
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136
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Dimerization and phosphorylation
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P10644-REGION-1
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Sites |
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Binding site
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202 - 202
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1
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cAMP 1
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P10644-BINDING-202
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Binding site
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211 - 211
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1
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cAMP 1
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P10644-BINDING-211
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Binding site
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326 - 326
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1
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cAMP 2
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P10644-BINDING-326
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Binding site
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335 - 335
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1
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cAMP 2
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P10644-BINDING-335
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Natural variations |
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Natural variant site
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9 - 9
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1
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S -> N (in CNC1; exhibits increased PKA activity which is attributed to decreased binding to cAMP and/or the catalytic subunit)
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VAR_046894
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Natural variant site
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74 - 74
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1
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R -> C (in CNC1; exhibits increased PKA activity which is attributed to decreased binding to cAMP and/or the catalytic subunit)
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VAR_046895
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Natural variant site
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146 - 146
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1
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R -> S (in CNC1; exhibits increased PKA activity which is attributed to decreased binding to cAMP and/or the catalytic subunit)
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VAR_046896
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Natural variant site
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183 - 183
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1
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D -> Y (in CNC1; exhibits increased PKA activity which is attributed to decreased binding to cAMP and/or the catalytic subunit)
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VAR_046897
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Natural variant site
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213 - 213
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1
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A -> D (in CNC1; exhibits increased PKA activity which is attributed to decreased binding to cAMP and/or the catalytic subunit)
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VAR_046898
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Natural variant site
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289 - 289
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1
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G -> W (in CNC1; exhibits increased PKA activity which is attributed to decreased binding to cAMP and/or the catalytic subunit)
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VAR_046899
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Amino acid modifications |
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Disulfide bond
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18 - 18
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1
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Interchain (with C-39) (By similarity)
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P10644-DISULFID-18
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Disulfide bond
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39 - 39
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1
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Interchain (with C-18) (By similarity)
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P10644-DISULFID-39
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Modified residue
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1 - 1
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1
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N-acetylmethionine
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P10644-MOD_RES-1
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Modified residue
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77 - 77
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1
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Phosphoserine (By similarity)
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P10644-MOD_RES-77
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Modified residue
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83 - 83
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1
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Phosphoserine
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P10644-MOD_RES-83
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Modified residue
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101 - 101
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1
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Phosphoserine (By similarity)
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P10644-MOD_RES-101
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1 |
MESGSTAASE |
EARSLRECEL |
YVQKHNIQAL |
LKDSIVQLCT |
ARPERPMAFL |
REYFERLEKE |
EAKQIQNLQK |
AGTRTDSRED |
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EISPPPPNPV |
VKGRRRRGAI |
SAEVYTEEDA |
ASYVRKVIPK |
DYKTMAALAK |
AIEKNVLFSH |
LDDNERSDIF |
DAMFSVSFIA |
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GETVIQQGDE |
GDNFYVIDQG |
ETDVYVNNEW |
ATSVGEGGSF |
GELALIYGTP |
RAATVKAKTN |
VKLWGIDRDS |
YRRILMGSTL |
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241 |
RKRKMYEEFL |
SKVSILESLD |
KWERLTVADA |
LEPVQFEDGQ |
KIVVQGEPGD |
EFFIILEGSA |
AVLQRRSENE |
EFVEVGRLGP |
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321 |
SDYFGEIALL |
MNRPRAATVV |
ARGPLKCVKL |
DRPRFERVLG |
PCSDILKRNI |
QQYNSFVSLS |
V |
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>sp|P10644|KAP0_human cAMP-dependent protein kinase type I-alpha regulatory subunit
MESGSTAASEEARSLRECELYVQKHNIQALLKDSIVQLCTARPERPMAFLREYFERLEKEEAKQIQNLQKAGTRTDSRED
EISPPPPNPVVKGRRRRGAISAEVYTEEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFSVSFIA
GETVIQQGDEGDNFYVIDQGETDVYVNNEWATSVGEGGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTL
RKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGP
SDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVSLSV
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Primary source |
Uniprot : B2R5T5
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Name |
Protein kinase, cAMP-dependent, regulatory, type I, alpha (Tissue specific extinguisher 1), isoform CRA_a [submitted name]
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Alternative name(s) |
cDNA FLJ40261 fis, clone TESTI2025609, highly similar to cAMP-dependent protein kinase type I-alpha regulatory subunit [submitted name] cDNA, FLJ92612, Homo sapiens protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) (PRKAR1A), mRNA [submitted name]
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Synonym(s) |
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Organism |
Homo sapiens
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Length |
381 aa
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Protein existence |
---
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General annotation (Comments)
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top
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Biological process
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regulation of protein amino acid phosphorylation [GO:0001932]
signal transduction [GO:0007165]
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Cellular component
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cAMP-dependent protein kinase complex [GO:0005952]
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Molecular function
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kinase activity [GO:0016301]
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With
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Uniprot accession
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IntAct
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Alternative product(s)
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top
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Feature key |
Position
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Length
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Description
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Feature identifier
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1 |
MESGSTAASE |
EARSLRECEL |
YVQKHNIQAL |
LKDSIVQLCT |
ARPERPMAFL |
REYFERLEKE |
EAKQIQNLQK |
AGTRTDSRED |
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81 |
EISPPPPNPV |
VKGRRRRGAI |
SAEVYTEEDA |
ASYVRKVIPK |
DYKTMAALAK |
AIEKNVLFSH |
LDDNERSDIF |
DAMFSVSFIA |
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161 |
GETVIQQGDE |
GDNFYVIDQG |
ETDVYVNNEW |
ATSVGEGGSF |
GELALIYGTP |
RAATVKAKTN |
VKLWGIDRDS |
YRRILMGSTL |
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241 |
RKRKMYEEFL |
SKVSILESLD |
KWERLTVADA |
LEPVQFEDGQ |
KIVVQGEPGD |
EFFIILEGSA |
AVLQRRSENE |
EFVEVGRLGP |
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321 |
SDYFGEIALL |
MNRPRAATVV |
ARGPLKCVKL |
DRPRFERVLG |
PCSDILKRNI |
QQYNSFVSLS |
V |
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>sp|B2R5T5|B2R5T5_human Protein kinase, cAMP-dependent, regulatory, type I, alpha (Tissue specific extinguisher 1), isoform CRA_a [submitted name]
MESGSTAASEEARSLRECELYVQKHNIQALLKDSIVQLCTARPERPMAFLREYFERLEKEEAKQIQNLQKAGTRTDSRED
EISPPPPNPVVKGRRRRGAISAEVYTEEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFSVSFIA
GETVIQQGDEGDNFYVIDQGETDVYVNNEWATSVGEGGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTL
RKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGP
SDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVSLSV
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