MAPK3, mRNA isoform 1 - Generality top
	Primary source RefSeq : NM_002746.2 (GI:91718898) Name Mitogen-activated protein kinase 3 (MAPK3), transcript variant 1 Type of transcript mRNA Organism Homo sapiens Length 1902 nt Map 16p11.2 Location Chromosome 16 (NC_000016.9)  strand : - 30125425...30126028   30127956...30128110   30128214...30128323   30128474...30128605   30128990...30129104   30129367...30129483   30129669...30129858   30133144...30133326   30134360...30134629
	Exon(s) top
	Exon(s) Start End Length is coding Exon 1 1 270 270 1 Exon 2 271 453 183 1 Exon 3 454 643 190 1 Exon 4 644 760 117 1 Exon 5 761 875 115 1 Exon 6 876 1007 132 1 Exon 7a 1008 1117 110 1 Exon 7c 1118 1272 155 1 Exon 8 1273 1876 604 1
	Variation(s) top
	ID Class Location Mutation Length is synonymous Source rs61736373 SNP 441 c/g 1 ? dbSNP rs61736375 SNP 634 a/g 1 ? dbSNP rs61736374 SNP 745 a/g 1 ? dbSNP rs61764216 SNP 763 c/t 1 ? dbSNP rs11546680 SNP 999 a/c 1 ? dbSNP rs55859133 SNP 1067 a/g 1 ? dbSNP rs61736377 SNP 1073 a/g 1 ? dbSNP rs1143695 SNP 1108 a/g 1 ? dbSNP rs61736376 SNP 1115 c/t 1 ? dbSNP rs41280866 SNP 1432 c/t 1 ? dbSNP rs41280864 SNP 1433 c/t 1 ? dbSNP rs41280862 SNP 1440 c/t 1 ? dbSNP rs41280860 SNP 1445 c/t 1 ? dbSNP rs3751867 SNP 1450 a/g 1 ? dbSNP rs7542 SNP 1462 c/g 1 ? dbSNP rs7698 SNP 1502 c/t 1 ? dbSNP rs1062543 SNP 1540 c/t 1 ? dbSNP rs13569 SNP 1557 a/t 1 ? dbSNP rs1042404 SNP 1640 c/t 1 ? dbSNP rs11865228 SNP 1642 c/t 1 ? dbSNP rs61764225 insertion 1494 -/tgct 4 ? dbSNP rs5816507 insertion 1635 -/c 1 ? dbSNP
	CDS top
	Primary source NCBI : CCDS10672 Nucleotide MAPK3, mRNA isoform 1[NM_002746.2] : 101...1240 Length 1140 Location Chromosome 16 (NC_000016.9)  strand : - 30127988...30128110   30128214...30128323   30128474...30128605   30128990...30129104   30129367...30129483   30129669...30129858   30133144...30133326   30134360...30134529   Start codon 1 Translation NP_002737.2
	Sequence top
	FASTA 1  CTGGCGCGCG CGGCCCTGCG GGTGACAGGC AGGCGGGAAG GGGCGGGGCC TCGGGCGGGG CCGCCGTGGG GAGGAGGGCG 81  GTGGGAGGGG AGGAGTGGAG ATGGCGGCGG CGGCGGCTCA GGGGGGCGGG GGCGGGGAGC CCCGTAGAAC CGAGGGGGTC 161  GGCCCGGGGG TCCCGGGGGA GGTGGAGATG GTGAAGGGGC AGCCGTTCGA CGTGGGCCCG CGCTACACGC AGTTGCAGTA 241  CATCGGCGAG GGCGCGTACG GCATGGTCAG CTCGGCCTAT GACCACGTGC GCAAGACTCG CGTGGCCATC AAGAAGATCA 321  GCCCCTTCGA ACATCAGACC TACTGCCAGC GCACGCTCCG GGAGATCCAG ATCCTGCTGC GCTTCCGCCA TGAGAATGTC 401  ATCGGCATCC GAGACATTCT GCGGGCGTCC ACCCTGGAAG CCATGAGAGA TGTCTACATT GTGCAGGACC TGATGGAGAC 481  TGACCTGTAC AAGTTGCTGA AAAGCCAGCA GCTGAGCAAT GACCATATCT GCTACTTCCT CTACCAGATC CTGCGGGGCC 561  TCAAGTACAT CCACTCCGCC AACGTGCTCC ACCGAGATCT AAAGCCCTCC AACCTGCTCA TCAACACCAC CTGCGACCTT 641  AAGATTTGTG ATTTCGGCCT GGCCCGGATT GCCGATCCTG AGCATGACCA CACCGGCTTC CTGACGGAGT ATGTGGCTAC 721  GCGCTGGTAC CGGGCCCCAG AGATCATGCT GAACTCCAAG GGCTATACCA AGTCCATCGA CATCTGGTCT GTGGGCTGCA 801  TTCTGGCTGA GATGCTCTCT AACCGGCCCA TCTTCCCTGG CAAGCACTAC CTGGATCAGC TCAACCACAT TCTGGGCATC 881  CTGGGCTCCC CATCCCAGGA GGACCTGAAT TGTATCATCA ACATGAAGGC CCGAAACTAC CTACAGTCTC TGCCCTCCAA 961  GACCAAGGTG GCTTGGGCCA AGCTTTTCCC CAAGTCAGAC TCCAAAGCCC TTGACCTGCT GGACCGGATG TTAACCTTTA 1041  ACCCCAATAA ACGGATCACA GTGGAGGAAG CGCTGGCTCA CCCCTACCTG GAGCAGTACT ATGACCCGAC GGATGAGCCA 1121  GTGGCCGAGG AGCCCTTCAC CTTCGCCATG GAGCTGGATG ACCTACCTAA GGAGCGGCTG AAGGAGCTCA TCTTCCAGGA 1201  GACAGCACGC TTCCAGCCCG GAGTGCTGGA GGCCCCCTAG CCCAGACAGA CATCTCTGCA CCCTGGGGCC TGGACCTGCC 1281  TCCTGCCTGC CCCTCTCCCG CCAGACTGTT AGAAAATGGA CACTGTGCCC AGCCCGGACC TTGGCAGCCC AGGCCGGGGT 1361  GGAGCATGGG CCTGGCCACC TCTCTCCTTT GCTGAGGCCT CCAGCTTCAG GCAGGCCAAG GCCTTCTCCT CCCCACCCGC 1441  CCTCCCCACG GGGCCTCGGG ACCTCAGGTG GCCCCAGTTC AATCTCCCGC TGCTGCTGCT GCGCCCTTAC CTTCCCCAGC 1521  GTCCCAGTCT CTGGCAGTTC TGGAATGGAA GGGTTCTGGC TGCCCCAACC TGCTGAAGGG CAGAGGTGGA GGGTGGGGGG 1601  CGCTGAGTAG GGACTCAGGG CCATGCCTGC CCCCCTCATC TCATTCAAAC CCCACCCTAG TTTCCCTGAA GGAACATTCC 1681  TTAGTCTCAA GGGCTAGCAT CCCTGAGGAG CCAGGCCGGG CCGAATCCCC TCCCTGTCAA AGCTGTCACT TCGCGTGCCC 1761  TCGCTGCTTC TGTGTGTGGT GAGCAGAAGT GGAGCTGGGG GGCGTGGAGA GCCCGGCGCC CCTGCCACCT CCCTGACCCG 1841  TCTAATATAT AAATATAGAG ATGTGTCTAT GGCTGAAAAA AAAAAAAAAA AAAAAAAAAA AA >gi|91718898|ref|NM_002746.2|Mitogen-activated protein kinase 3 (MAPK3), transcript variant 1 CTGGCGCGCGCGGCCCTGCGGGTGACAGGCAGGCGGGAAGGGGCGGGGCCTCGGGCGGGGCCGCCGTGGGGAGGAGGGCG GTGGGAGGGGAGGAGTGGAGATGGCGGCGGCGGCGGCTCAGGGGGGCGGGGGCGGGGAGCCCCGTAGAACCGAGGGGGTC GGCCCGGGGGTCCCGGGGGAGGTGGAGATGGTGAAGGGGCAGCCGTTCGACGTGGGCCCGCGCTACACGCAGTTGCAGTA CATCGGCGAGGGCGCGTACGGCATGGTCAGCTCGGCCTATGACCACGTGCGCAAGACTCGCGTGGCCATCAAGAAGATCA GCCCCTTCGAACATCAGACCTACTGCCAGCGCACGCTCCGGGAGATCCAGATCCTGCTGCGCTTCCGCCATGAGAATGTC ATCGGCATCCGAGACATTCTGCGGGCGTCCACCCTGGAAGCCATGAGAGATGTCTACATTGTGCAGGACCTGATGGAGAC TGACCTGTACAAGTTGCTGAAAAGCCAGCAGCTGAGCAATGACCATATCTGCTACTTCCTCTACCAGATCCTGCGGGGCC TCAAGTACATCCACTCCGCCAACGTGCTCCACCGAGATCTAAAGCCCTCCAACCTGCTCATCAACACCACCTGCGACCTT AAGATTTGTGATTTCGGCCTGGCCCGGATTGCCGATCCTGAGCATGACCACACCGGCTTCCTGACGGAGTATGTGGCTAC GCGCTGGTACCGGGCCCCAGAGATCATGCTGAACTCCAAGGGCTATACCAAGTCCATCGACATCTGGTCTGTGGGCTGCA TTCTGGCTGAGATGCTCTCTAACCGGCCCATCTTCCCTGGCAAGCACTACCTGGATCAGCTCAACCACATTCTGGGCATC CTGGGCTCCCCATCCCAGGAGGACCTGAATTGTATCATCAACATGAAGGCCCGAAACTACCTACAGTCTCTGCCCTCCAA GACCAAGGTGGCTTGGGCCAAGCTTTTCCCCAAGTCAGACTCCAAAGCCCTTGACCTGCTGGACCGGATGTTAACCTTTA ACCCCAATAAACGGATCACAGTGGAGGAAGCGCTGGCTCACCCCTACCTGGAGCAGTACTATGACCCGACGGATGAGCCA GTGGCCGAGGAGCCCTTCACCTTCGCCATGGAGCTGGATGACCTACCTAAGGAGCGGCTGAAGGAGCTCATCTTCCAGGA GACAGCACGCTTCCAGCCCGGAGTGCTGGAGGCCCCCTAGCCCAGACAGACATCTCTGCACCCTGGGGCCTGGACCTGCC TCCTGCCTGCCCCTCTCCCGCCAGACTGTTAGAAAATGGACACTGTGCCCAGCCCGGACCTTGGCAGCCCAGGCCGGGGT GGAGCATGGGCCTGGCCACCTCTCTCCTTTGCTGAGGCCTCCAGCTTCAGGCAGGCCAAGGCCTTCTCCTCCCCACCCGC CCTCCCCACGGGGCCTCGGGACCTCAGGTGGCCCCAGTTCAATCTCCCGCTGCTGCTGCTGCGCCCTTACCTTCCCCAGC GTCCCAGTCTCTGGCAGTTCTGGAATGGAAGGGTTCTGGCTGCCCCAACCTGCTGAAGGGCAGAGGTGGAGGGTGGGGGG CGCTGAGTAGGGACTCAGGGCCATGCCTGCCCCCCTCATCTCATTCAAACCCCACCCTAGTTTCCCTGAAGGAACATTCC TTAGTCTCAAGGGCTAGCATCCCTGAGGAGCCAGGCCGGGCCGAATCCCCTCCCTGTCAAAGCTGTCACTTCGCGTGCCC TCGCTGCTTCTGTGTGTGGTGAGCAGAAGTGGAGCTGGGGGGCGTGGAGAGCCCGGCGCCCCTGCCACCTCCCTGACCCG TCTAATATATAAATATAGAGATGTGTCTATGGCTGAAAAAAAAAAAAAAAAAAAAAAAAAAA

	MAPK3, mRNA isoform 2 - Generality top
	Primary source RefSeq : NM_001040056.1 (GI:91718896) Name Mitogen-activated protein kinase 3 (MAPK3), transcript variant 2 Type of transcript mRNA Organism Homo sapiens Length 2005 nt Map 16p11.2 Location Chromosome 16 (NC_000016.9)  strand : - 30125425...30126028   30127956...30128323   30128474...30128605   30128990...30129104   30129367...30129483   30129669...30129858   30133144...30133326   30134360...30134629
	Exon(s) top
	Exon(s) Start End Length is coding Exon 1 1 270 270 1 Exon 2 271 453 183 1 Exon 3 454 643 190 1 Exon 4 644 760 117 1 Exon 5 761 875 115 1 Exon 6 876 1007 132 1 Exon 7b 1008 1375 368 1 Exon 8 1376 1979 604 1
	Variation(s) top
	ID Class Location Mutation Length is synonymous Source rs55649456 SNP 1144 a/g 1 ? dbSNP rs41292376 SNP 1164 a/g 1 ? dbSNP rs41291696 SNP 1165 a/g 1 ? dbSNP rs61764219 SNP 1170 c/t 1 ? dbSNP
	CDS top
	Primary source NCBI : CCDS42149 Nucleotide MAPK3, mRNA isoform 2[NM_001040056.1] : 101...1174 Length 1074 Location Chromosome 16 (NC_000016.9)  strand : - 30128157...30128323   30128474...30128605   30128990...30129104   30129367...30129483   30129669...30129858   30133144...30133326   30134360...30134529   Start codon 1 Translation NP_001035145.1
	Sequence top
	FASTA 1  CTGGCGCGCG CGGCCCTGCG GGTGACAGGC AGGCGGGAAG GGGCGGGGCC TCGGGCGGGG CCGCCGTGGG GAGGAGGGCG 81  GTGGGAGGGG AGGAGTGGAG ATGGCGGCGG CGGCGGCTCA GGGGGGCGGG GGCGGGGAGC CCCGTAGAAC CGAGGGGGTC 161  GGCCCGGGGG TCCCGGGGGA GGTGGAGATG GTGAAGGGGC AGCCGTTCGA CGTGGGCCCG CGCTACACGC AGTTGCAGTA 241  CATCGGCGAG GGCGCGTACG GCATGGTCAG CTCGGCCTAT GACCACGTGC GCAAGACTCG CGTGGCCATC AAGAAGATCA 321  GCCCCTTCGA ACATCAGACC TACTGCCAGC GCACGCTCCG GGAGATCCAG ATCCTGCTGC GCTTCCGCCA TGAGAATGTC 401  ATCGGCATCC GAGACATTCT GCGGGCGTCC ACCCTGGAAG CCATGAGAGA TGTCTACATT GTGCAGGACC TGATGGAGAC 481  TGACCTGTAC AAGTTGCTGA AAAGCCAGCA GCTGAGCAAT GACCATATCT GCTACTTCCT CTACCAGATC CTGCGGGGCC 561  TCAAGTACAT CCACTCCGCC AACGTGCTCC ACCGAGATCT AAAGCCCTCC AACCTGCTCA TCAACACCAC CTGCGACCTT 641  AAGATTTGTG ATTTCGGCCT GGCCCGGATT GCCGATCCTG AGCATGACCA CACCGGCTTC CTGACGGAGT ATGTGGCTAC 721  GCGCTGGTAC CGGGCCCCAG AGATCATGCT GAACTCCAAG GGCTATACCA AGTCCATCGA CATCTGGTCT GTGGGCTGCA 801  TTCTGGCTGA GATGCTCTCT AACCGGCCCA TCTTCCCTGG CAAGCACTAC CTGGATCAGC TCAACCACAT TCTGGGCATC 881  CTGGGCTCCC CATCCCAGGA GGACCTGAAT TGTATCATCA ACATGAAGGC CCGAAACTAC CTACAGTCTC TGCCCTCCAA 961  GACCAAGGTG GCTTGGGCCA AGCTTTTCCC CAAGTCAGAC TCCAAAGCCC TTGACCTGCT GGACCGGATG TTAACCTTTA 1041  ACCCCAATAA ACGGATCACA GTGGAGGAAG CGCTGGCTCA CCCCTACCTG GAGCAGTACT ATGACCCGAC GGATGAGGTG 1121  GGCCAGTCCC CAGCAGCAGT GGGGCTGGGG GCAGGGGAGC AGGGGGGCAC GTAGGCATCC CCCATGCCAG GCCTGAGCCT 1201  TGCTGTCTCT ACCACCCCAG CCAGTGGCCG AGGAGCCCTT CACCTTCGCC ATGGAGCTGG ATGACCTACC TAAGGAGCGG 1281  CTGAAGGAGC TCATCTTCCA GGAGACAGCA CGCTTCCAGC CCGGAGTGCT GGAGGCCCCC TAGCCCAGAC AGACATCTCT 1361  GCACCCTGGG GCCTGGACCT GCCTCCTGCC TGCCCCTCTC CCGCCAGACT GTTAGAAAAT GGACACTGTG CCCAGCCCGG 1441  ACCTTGGCAG CCCAGGCCGG GGTGGAGCAT GGGCCTGGCC ACCTCTCTCC TTTGCTGAGG CCTCCAGCTT CAGGCAGGCC 1521  AAGGCCTTCT CCTCCCCACC CGCCCTCCCC ACGGGGCCTC GGGACCTCAG GTGGCCCCAG TTCAATCTCC CGCTGCTGCT 1601  GCTGCGCCCT TACCTTCCCC AGCGTCCCAG TCTCTGGCAG TTCTGGAATG GAAGGGTTCT GGCTGCCCCA ACCTGCTGAA 1681  GGGCAGAGGT GGAGGGTGGG GGGCGCTGAG TAGGGACTCA GGGCCATGCC TGCCCCCCTC ATCTCATTCA AACCCCACCC 1761  TAGTTTCCCT GAAGGAACAT TCCTTAGTCT CAAGGGCTAG CATCCCTGAG GAGCCAGGCC GGGCCGAATC CCCTCCCTGT 1841  CAAAGCTGTC ACTTCGCGTG CCCTCGCTGC TTCTGTGTGT GGTGAGCAGA AGTGGAGCTG GGGGGCGTGG AGAGCCCGGC 1921  GCCCCTGCCA CCTCCCTGAC CCGTCTAATA TATAAATATA GAGATGTGTC TATGGCTGAA AAAAAAAAAA AAAAAAAAAA 2001  AAAAA >gi|91718896|ref|NM_001040056.1|Mitogen-activated protein kinase 3 (MAPK3), transcript variant 2 CTGGCGCGCGCGGCCCTGCGGGTGACAGGCAGGCGGGAAGGGGCGGGGCCTCGGGCGGGGCCGCCGTGGGGAGGAGGGCG GTGGGAGGGGAGGAGTGGAGATGGCGGCGGCGGCGGCTCAGGGGGGCGGGGGCGGGGAGCCCCGTAGAACCGAGGGGGTC GGCCCGGGGGTCCCGGGGGAGGTGGAGATGGTGAAGGGGCAGCCGTTCGACGTGGGCCCGCGCTACACGCAGTTGCAGTA CATCGGCGAGGGCGCGTACGGCATGGTCAGCTCGGCCTATGACCACGTGCGCAAGACTCGCGTGGCCATCAAGAAGATCA GCCCCTTCGAACATCAGACCTACTGCCAGCGCACGCTCCGGGAGATCCAGATCCTGCTGCGCTTCCGCCATGAGAATGTC ATCGGCATCCGAGACATTCTGCGGGCGTCCACCCTGGAAGCCATGAGAGATGTCTACATTGTGCAGGACCTGATGGAGAC TGACCTGTACAAGTTGCTGAAAAGCCAGCAGCTGAGCAATGACCATATCTGCTACTTCCTCTACCAGATCCTGCGGGGCC TCAAGTACATCCACTCCGCCAACGTGCTCCACCGAGATCTAAAGCCCTCCAACCTGCTCATCAACACCACCTGCGACCTT AAGATTTGTGATTTCGGCCTGGCCCGGATTGCCGATCCTGAGCATGACCACACCGGCTTCCTGACGGAGTATGTGGCTAC GCGCTGGTACCGGGCCCCAGAGATCATGCTGAACTCCAAGGGCTATACCAAGTCCATCGACATCTGGTCTGTGGGCTGCA TTCTGGCTGAGATGCTCTCTAACCGGCCCATCTTCCCTGGCAAGCACTACCTGGATCAGCTCAACCACATTCTGGGCATC CTGGGCTCCCCATCCCAGGAGGACCTGAATTGTATCATCAACATGAAGGCCCGAAACTACCTACAGTCTCTGCCCTCCAA GACCAAGGTGGCTTGGGCCAAGCTTTTCCCCAAGTCAGACTCCAAAGCCCTTGACCTGCTGGACCGGATGTTAACCTTTA ACCCCAATAAACGGATCACAGTGGAGGAAGCGCTGGCTCACCCCTACCTGGAGCAGTACTATGACCCGACGGATGAGGTG GGCCAGTCCCCAGCAGCAGTGGGGCTGGGGGCAGGGGAGCAGGGGGGCACGTAGGCATCCCCCATGCCAGGCCTGAGCCT TGCTGTCTCTACCACCCCAGCCAGTGGCCGAGGAGCCCTTCACCTTCGCCATGGAGCTGGATGACCTACCTAAGGAGCGG CTGAAGGAGCTCATCTTCCAGGAGACAGCACGCTTCCAGCCCGGAGTGCTGGAGGCCCCCTAGCCCAGACAGACATCTCT GCACCCTGGGGCCTGGACCTGCCTCCTGCCTGCCCCTCTCCCGCCAGACTGTTAGAAAATGGACACTGTGCCCAGCCCGG ACCTTGGCAGCCCAGGCCGGGGTGGAGCATGGGCCTGGCCACCTCTCTCCTTTGCTGAGGCCTCCAGCTTCAGGCAGGCC AAGGCCTTCTCCTCCCCACCCGCCCTCCCCACGGGGCCTCGGGACCTCAGGTGGCCCCAGTTCAATCTCCCGCTGCTGCT GCTGCGCCCTTACCTTCCCCAGCGTCCCAGTCTCTGGCAGTTCTGGAATGGAAGGGTTCTGGCTGCCCCAACCTGCTGAA GGGCAGAGGTGGAGGGTGGGGGGCGCTGAGTAGGGACTCAGGGCCATGCCTGCCCCCCTCATCTCATTCAAACCCCACCC TAGTTTCCCTGAAGGAACATTCCTTAGTCTCAAGGGCTAGCATCCCTGAGGAGCCAGGCCGGGCCGAATCCCCTCCCTGT CAAAGCTGTCACTTCGCGTGCCCTCGCTGCTTCTGTGTGTGGTGAGCAGAAGTGGAGCTGGGGGGCGTGGAGAGCCCGGC GCCCCTGCCACCTCCCTGACCCGTCTAATATATAAATATAGAGATGTGTCTATGGCTGAAAAAAAAAAAAAAAAAAAAAA AAAAA

	MAPK3, mRNA isoform 3 - Generality top
	Primary source RefSeq : NM_001109891.1 (GI:158138506) Name Mitogen-activated protein kinase 3 (MAPK3), transcript variant 3 Type of transcript mRNA Organism Homo sapiens Length 1770 nt Map 16p11.2 Location Chromosome 16 (NC_000016.9)  strand : - 30125425...30126028   30127956...30128110   30128214...30128323   30128990...30129104   30129367...30129483   30129669...30129858   30133144...30133326   30134360...30134629
	Exon(s) top
	Exon(s) Start End Length is coding Exon 1 1 270 270 1 Exon 2 271 453 183 1 Exon 3 454 643 190 1 Exon 4 644 760 117 1 Exon 5 761 875 115 1 Exon 7a 876 985 110 1 Exon 7c 986 1140 155 1 Exon 8 1141 1744 604 1
	Variation(s) top
	ID Class Location Mutation Length is synonymous Source
	CDS top
	Primary source NCBI : CCDS42148 Nucleotide MAPK3, mRNA isoform 3[NM_001109891.1] : 101...1108 Length 1008 Location Chromosome 16 (NC_000016.9)  strand : - 30127988...30128110   30128214...30128323   30128990...30129104   30129367...30129483   30129669...30129858   30133144...30133326   30134360...30134529   Start codon 1 Translation NP_001103361.1
	Sequence top
	FASTA 1  CTGGCGCGCG CGGCCCTGCG GGTGACAGGC AGGCGGGAAG GGGCGGGGCC TCGGGCGGGG CCGCCGTGGG GAGGAGGGCG 81  GTGGGAGGGG AGGAGTGGAG ATGGCGGCGG CGGCGGCTCA GGGGGGCGGG GGCGGGGAGC CCCGTAGAAC CGAGGGGGTC 161  GGCCCGGGGG TCCCGGGGGA GGTGGAGATG GTGAAGGGGC AGCCGTTCGA CGTGGGCCCG CGCTACACGC AGTTGCAGTA 241  CATCGGCGAG GGCGCGTACG GCATGGTCAG CTCGGCCTAT GACCACGTGC GCAAGACTCG CGTGGCCATC AAGAAGATCA 321  GCCCCTTCGA ACATCAGACC TACTGCCAGC GCACGCTCCG GGAGATCCAG ATCCTGCTGC GCTTCCGCCA TGAGAATGTC 401  ATCGGCATCC GAGACATTCT GCGGGCGTCC ACCCTGGAAG CCATGAGAGA TGTCTACATT GTGCAGGACC TGATGGAGAC 481  TGACCTGTAC AAGTTGCTGA AAAGCCAGCA GCTGAGCAAT GACCATATCT GCTACTTCCT CTACCAGATC CTGCGGGGCC 561  TCAAGTACAT CCACTCCGCC AACGTGCTCC ACCGAGATCT AAAGCCCTCC AACCTGCTCA TCAACACCAC CTGCGACCTT 641  AAGATTTGTG ATTTCGGCCT GGCCCGGATT GCCGATCCTG AGCATGACCA CACCGGCTTC CTGACGGAGT ATGTGGCTAC 721  GCGCTGGTAC CGGGCCCCAG AGATCATGCT GAACTCCAAG GGCTATACCA AGTCCATCGA CATCTGGTCT GTGGGCTGCA 801  TTCTGGCTGA GATGCTCTCT AACCGGCCCA TCTTCCCTGG CAAGCACTAC CTGGATCAGC TCAACCACAT TCTGGCCCTT 881  GACCTGCTGG ACCGGATGTT AACCTTTAAC CCCAATAAAC GGATCACAGT GGAGGAAGCG CTGGCTCACC CCTACCTGGA 961  GCAGTACTAT GACCCGACGG ATGAGCCAGT GGCCGAGGAG CCCTTCACCT TCGCCATGGA GCTGGATGAC CTACCTAAGG 1041  AGCGGCTGAA GGAGCTCATC TTCCAGGAGA CAGCACGCTT CCAGCCCGGA GTGCTGGAGG CCCCCTAGCC CAGACAGACA 1121  TCTCTGCACC CTGGGGCCTG GACCTGCCTC CTGCCTGCCC CTCTCCCGCC AGACTGTTAG AAAATGGACA CTGTGCCCAG 1201  CCCGGACCTT GGCAGCCCAG GCCGGGGTGG AGCATGGGCC TGGCCACCTC TCTCCTTTGC TGAGGCCTCC AGCTTCAGGC 1281  AGGCCAAGGC CTTCTCCTCC CCACCCGCCC TCCCCACGGG GCCTCGGGAC CTCAGGTGGC CCCAGTTCAA TCTCCCGCTG 1361  CTGCTGCTGC GCCCTTACCT TCCCCAGCGT CCCAGTCTCT GGCAGTTCTG GAATGGAAGG GTTCTGGCTG CCCCAACCTG 1441  CTGAAGGGCA GAGGTGGAGG GTGGGGGGCG CTGAGTAGGG ACTCAGGGCC ATGCCTGCCC CCCTCATCTC ATTCAAACCC 1521  CACCCTAGTT TCCCTGAAGG AACATTCCTT AGTCTCAAGG GCTAGCATCC CTGAGGAGCC AGGCCGGGCC GAATCCCCTC 1601  CCTGTCAAAG CTGTCACTTC GCGTGCCCTC GCTGCTTCTG TGTGTGGTGA GCAGAAGTGG AGCTGGGGGG CGTGGAGAGC 1681  CCGGCGCCCC TGCCACCTCC CTGACCCGTC TAATATATAA ATATAGAGAT GTGTCTATGG CTGAAAAAAA AAAAAAAAAA 1761  AAAAAAAAAA >gi|158138506|ref|NM_001109891.1|Mitogen-activated protein kinase 3 (MAPK3), transcript variant 3 CTGGCGCGCGCGGCCCTGCGGGTGACAGGCAGGCGGGAAGGGGCGGGGCCTCGGGCGGGGCCGCCGTGGGGAGGAGGGCG GTGGGAGGGGAGGAGTGGAGATGGCGGCGGCGGCGGCTCAGGGGGGCGGGGGCGGGGAGCCCCGTAGAACCGAGGGGGTC GGCCCGGGGGTCCCGGGGGAGGTGGAGATGGTGAAGGGGCAGCCGTTCGACGTGGGCCCGCGCTACACGCAGTTGCAGTA CATCGGCGAGGGCGCGTACGGCATGGTCAGCTCGGCCTATGACCACGTGCGCAAGACTCGCGTGGCCATCAAGAAGATCA GCCCCTTCGAACATCAGACCTACTGCCAGCGCACGCTCCGGGAGATCCAGATCCTGCTGCGCTTCCGCCATGAGAATGTC ATCGGCATCCGAGACATTCTGCGGGCGTCCACCCTGGAAGCCATGAGAGATGTCTACATTGTGCAGGACCTGATGGAGAC TGACCTGTACAAGTTGCTGAAAAGCCAGCAGCTGAGCAATGACCATATCTGCTACTTCCTCTACCAGATCCTGCGGGGCC TCAAGTACATCCACTCCGCCAACGTGCTCCACCGAGATCTAAAGCCCTCCAACCTGCTCATCAACACCACCTGCGACCTT AAGATTTGTGATTTCGGCCTGGCCCGGATTGCCGATCCTGAGCATGACCACACCGGCTTCCTGACGGAGTATGTGGCTAC GCGCTGGTACCGGGCCCCAGAGATCATGCTGAACTCCAAGGGCTATACCAAGTCCATCGACATCTGGTCTGTGGGCTGCA TTCTGGCTGAGATGCTCTCTAACCGGCCCATCTTCCCTGGCAAGCACTACCTGGATCAGCTCAACCACATTCTGGCCCTT GACCTGCTGGACCGGATGTTAACCTTTAACCCCAATAAACGGATCACAGTGGAGGAAGCGCTGGCTCACCCCTACCTGGA GCAGTACTATGACCCGACGGATGAGCCAGTGGCCGAGGAGCCCTTCACCTTCGCCATGGAGCTGGATGACCTACCTAAGG AGCGGCTGAAGGAGCTCATCTTCCAGGAGACAGCACGCTTCCAGCCCGGAGTGCTGGAGGCCCCCTAGCCCAGACAGACA TCTCTGCACCCTGGGGCCTGGACCTGCCTCCTGCCTGCCCCTCTCCCGCCAGACTGTTAGAAAATGGACACTGTGCCCAG CCCGGACCTTGGCAGCCCAGGCCGGGGTGGAGCATGGGCCTGGCCACCTCTCTCCTTTGCTGAGGCCTCCAGCTTCAGGC AGGCCAAGGCCTTCTCCTCCCCACCCGCCCTCCCCACGGGGCCTCGGGACCTCAGGTGGCCCCAGTTCAATCTCCCGCTG CTGCTGCTGCGCCCTTACCTTCCCCAGCGTCCCAGTCTCTGGCAGTTCTGGAATGGAAGGGTTCTGGCTGCCCCAACCTG CTGAAGGGCAGAGGTGGAGGGTGGGGGGCGCTGAGTAGGGACTCAGGGCCATGCCTGCCCCCCTCATCTCATTCAAACCC CACCCTAGTTTCCCTGAAGGAACATTCCTTAGTCTCAAGGGCTAGCATCCCTGAGGAGCCAGGCCGGGCCGAATCCCCTC CCTGTCAAAGCTGTCACTTCGCGTGCCCTCGCTGCTTCTGTGTGTGGTGAGCAGAAGTGGAGCTGGGGGGCGTGGAGAGC CCGGCGCCCCTGCCACCTCCCTGACCCGTCTAATATATAAATATAGAGATGTGTCTATGGCTGAAAAAAAAAAAAAAAAA AAAAAAAAAA

	P27361 - Generality top
	Primary source Uniprot : P27361 Name Mitogen-activated protein kinase 3 Alternative name(s) ERT2 Extracellular signal-regulated kinase 1 Insulin-stimulated MAP2 kinase MAP kinase isoform p44 Microtubule-associated protein 2 kinase Mitogen-activated protein kinase 1 p44-ERK1 Synonym(s) ERK-1 MAP kinase 1 MAP kinase 3 MAPK 1 MAPK 3 p44-MAPK Organism Homo sapiens Length 379 aa Protein existence ---
	External Links top
	ArrayExpress P27361   BRENDA 2.7.11.24   Prints PR01770   Smart SM00220   Refseq NP_002737.2   NP_001103361.1   NP_001035145.1   Uniprot P27361   EBI EBI-73995   InterPro IPR002290   IPR008271   IPR017442   IPR017441   IPR000719   IPR003527   IPR011009   IPR008349   KEGG hsa:5595   PDB 2ZOQ   PDBsum 2ZOQ   PROSITE PS00108   PS50011   PS00107   PS01351   Pfam PF00069   SUPFAM SSF56112
	General annotation (Comments) top
	Catalytic activity ATP + a protein = ADP + a phosphoprotein. Cofactor Magnesium (By similarity). Domain The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases. Enzyme regulation Activated by tyrosine phosphorylation in response to insulin and NGF. Function Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1 (By similarity). Phosphorylates heat shock factor protein 4 (HSF4). Ptm Dually phosphorylated on Thr-202 and Tyr-204, which activates the enzyme. Similarity Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. Contains 1 protein kinase domain. Subunit Interacts with MORG1 (By similarity). Binds to HIV-1 Nef. This interaction inhibits its kinase activity. Interacts with HSF4 and NISCH. Interacts with ARRB2. Interacts with ADAM15.
	Ontologies top
	Biological process protein amino acid phosphorylation [GO:0006468] cell cycle [GO:0007049] Ras protein signal transduction [GO:0007265] interspecies interaction between organisms [GO:0044419] Cellular component nucleoplasm [GO:0005654] cytosol [GO:0005829] microtubule cytoskeleton [GO:0015630] Molecular function MAP kinase activity [GO:0004707] ATP binding [GO:0005524]
	Binary interactions top
	With Uniprot accession IntAct PTPRK Q15262 EBI-73995,EBI-474052 PTPRG P23470 EBI-73995, PTPRJ Q12913 EBI-73995,EBI-2264500 AKR1C1 Q04828 EBI-73995,EBI-2116455 ELK1 P19419 EBI-73995, PTPRC P08575 EBI-73995,EBI-1341 DAPK1 P53355 EBI-73995,EBI-358616 PTPRO Q16827 EBI-73995,EBI-723739 RPS6KA4 O75676 EBI-73995,EBI-73933 PTPRB P23467 EBI-73995,EBI-1265766 FKBP2 P26885 EBI-73995,EBI-719873 TTYH3 Q9C0H2 EBI-73995,EBI-2116541
	Alternative product(s) top
	Sequence annotation top
	Feature key Position Length Description Feature identifier Molecule processing           Initiator methionine 1 - 1 1 Removed P27361-INIT_MET-1 Region           Domain 42 - 330 289 Protein kinase P27361-DOMAIN-42 Motif 202 - 204 3 TXY P27361-MOTIF-202 Nucleotide binding 48 - 56 9 ATP (By similarity) P27361-NP_BIND-48 Sites           Active site 166 - 166 1 Proton acceptor (By similarity) P27361-ACT_SITE-166 Binding site 71 - 71 1 ATP (By similarity) P27361-BINDING-71 Natural variations           Natural variant site 323 - 323 1 E -> K (in dbSNP:rs55859133) VAR_042253 Amino acid modifications           Modified residue 2 - 2 1 N-acetylalanine P27361-MOD_RES-2 Modified residue 170 - 170 1 Phosphoserine P27361-MOD_RES-170 Modified residue 198 - 198 1 Phosphothreonine P27361-MOD_RES-198 Modified residue 202 - 202 1 Phosphothreonine P27361-MOD_RES-202 Modified residue 204 - 204 1 Phosphotyrosine P27361-MOD_RES-204
	Sequence top
	FASTA 1  MAAAAAQGGG GGEPRRTEGV GPGVPGEVEM VKGQPFDVGP RYTQLQYIGE GAYGMVSSAY DHVRKTRVAI KKISPFEHQT 81  YCQRTLREIQ ILLRFRHENV IGIRDILRAS TLEAMRDVYI VQDLMETDLY KLLKSQQLSN DHICYFLYQI LRGLKYIHSA 161  NVLHRDLKPS NLLINTTCDL KICDFGLARI ADPEHDHTGF LTEYVATRWY RAPEIMLNSK GYTKSIDIWS VGCILAEMLS 241  NRPIFPGKHY LDQLNHILGI LGSPSQEDLN CIINMKARNY LQSLPSKTKV AWAKLFPKSD SKALDLLDRM LTFNPNKRIT 321  VEEALAHPYL EQYYDPTDEP VAEEPFTFAM ELDDLPKERL KELIFQETAR FQPGVLEAP >sp|P27361|MK03_human Mitogen-activated protein kinase 3 MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQT YCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSA NVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRIT VEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERLKELIFQETARFQPGVLEAP

	Q8NHX1 - Generality top
	Primary source Uniprot : Q8NHX1 Name Extracellular signal-related kinase 1b [submitted name] Alternative name(s) Synonym(s) Organism Homo sapiens Length 357 aa Protein existence ---
	External Links top
	ArrayExpress Q8NHX1   Prints PR01770   Smart SM00220   Refseq NP_001035145.1   Uniprot Q8NHX1   InterPro IPR002290   IPR017442   IPR017441   IPR000719   IPR003527   IPR011009   IPR008349   KEGG hsa:5595   PROSITE PS50011   PS00107   PS01351   Pfam PF00069   SUPFAM SSF56112
	General annotation (Comments) top
	Catalytic activity ATP + a protein = ADP + a phosphoprotein. Similarity Contains 1 protein kinase domain.
	Ontologies top
	Biological process protein amino acid phosphorylation [GO:0006468] Cellular component nucleus [GO:0005634] cytoskeleton [GO:0005856] Molecular function MAP kinase activity [GO:0004707] ATP binding [GO:0005524]
	Binary interactions top
	With Uniprot accession IntAct
	Alternative product(s) top
	Sequence annotation top
	Feature key Position Length Description Feature identifier
	Sequence top
	FASTA 1  MAAAAAQGGG GGEPRRTEGV GPGVPGEVEM VKGQPFDVGP RYTQLQYIGE GAYGMVSSAY DHVRKTRVAI KKISPFEHQT 81  YCQRTLREIQ ILLRFRHENV IGIRDILRAS TLEAMRDVYI VQDLMETDLY KLLKSQQLSN DHICYFLYQI LRGLKYIHSA 161  NVLHRDLKPS NLLSNTTCDL KICDFGLARI ADPEHDHTGF LTEYVATRWY RAPEIMLNSK GYTKSIDIWS VGCILAEMLS 241  NRPIFPGKHY LDQLNHILGI LGSPSQEDLN CIINMKARNY LQSLPSKTKV AWAKLFPKSD SKALDLLDRM LTFNPNKRIT 321  VEEALAHPYL EQYYDPTDEV GQSPAAVGLG AGEQGGT >sp|Q8NHX1|Q8NHX1_human Extracellular signal-related kinase 1b [submitted name] MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQT YCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSA NVLHRDLKPSNLLSNTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS NRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRIT VEEALAHPYLEQYYDPTDEVGQSPAAVGLGAGEQGGT

	A8CZ58 - Generality top
	Primary source Uniprot : A8CZ58 Name Extracellular signal-regulated kinase-1 splice variant [submitted name] Alternative name(s) Mitogen-activated protein kinase 3, isoform CRA_a [submitted name] Synonym(s) Organism Homo sapiens Length 335 aa Protein existence ---
	External Links top
	Prints PR01770   Smart SM00220   Refseq NP_001103361.1   Uniprot A8CZ58   InterPro IPR002290   IPR008271   IPR017442   IPR017441   IPR000719   IPR003527   IPR011009   IPR008349   PROSITE PS00108   PS50011   PS00107   PS01351   Pfam PF00069   SUPFAM SSF56112
	General annotation (Comments) top
	Catalytic activity ATP + a protein = ADP + a phosphoprotein. Similarity Belongs to the protein kinase superfamily. Contains 1 protein kinase domain.
	Ontologies top
	Biological process protein amino acid phosphorylation [GO:0006468] Molecular function MAP kinase activity [GO:0004707] ATP binding [GO:0005524]
	Binary interactions top
	With Uniprot accession IntAct
	Alternative product(s) top
	Sequence annotation top
	Feature key Position Length Description Feature identifier
	Sequence top
	FASTA 1  MAAAAAQGGG GGEPRRTEGV GPGVPGEVEM VKGQPFDVGP RYTQLQYIGE GAYGMVSSAY DHVRKTRVAI KKISPFEHQT 81  YCQRTLREIQ ILLRFRHENV IGIRDILRAS TLEAMRDVYI VQDLMETDLY KLLKSQQLSN DHICYFLYQI LRGLKYIHSA 161  NVLHRDLKPS NLLINTTCDL KICDFGLARI ADPEHDHTGF LTEYVATRWY RAPEIMLNSK GYTKSIDIWS VGCILAEMLS 241  NRPIFPGKHY LDQLNHILAL DLLDRMLTFN PNKRITVEEA LAHPYLEQYY DPTDEPVAEE PFTFAMELDD LPKERLKELI 321  FQETARFQPG VLEAP >sp|A8CZ58|A8CZ58_human Extracellular signal-regulated kinase-1 splice variant [submitted name] MAAAAAQGGGGGEPRRTEGVGPGVPGEVEMVKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQT YCQRTLREIQILLRFRHENVIGIRDILRASTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSA NVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLS NRPIFPGKHYLDQLNHILALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERLKELI FQETARFQPGVLEAP

	Q9BWJ1 - Generality top
	Primary source Uniprot : Q9BWJ1 Name MAPK3 protein [submitted name] Alternative name(s) Synonym(s) Organism Homo sapiens Length 119 aa Protein existence ---
	External Links top
	ArrayExpress Q9BWJ1   Prints PR01770   Refseq NP_001103361.1   Uniprot Q9BWJ1   InterPro IPR017442   IPR011009   IPR008349   Pfam PF00069   SUPFAM SSF56112
	General annotation (Comments) top
	Ontologies top
	Biological process protein amino acid phosphorylation [GO:0006468] Molecular function MAP kinase activity [GO:0004707] ATP binding [GO:0005524]
	Binary interactions top
	With Uniprot accession IntAct
	Alternative product(s) top
	Sequence annotation top
	Feature key Position Length Description Feature identifier
	Sequence top
	FASTA 1  LGSPSQEDLN CIINMKARNY LQSLPSKTKV AWAKLFPKSD SKALDLLDRM LTFNPNKRIT VEEALAHPYL EQYYDPTDEP 81  VAEEPFTFAM ELDDLPKERL KELIFQETAR FQPGVLEAP >sp|Q9BWJ1|Q9BWJ1_human MAPK3 protein [submitted name] LGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEP VAEEPFTFAMELDDLPKERLKELIFQETARFQPGVLEAP