(BAK1) BCL2-antagonist/killer 1 [Homo sapiens]
Gene
Transcript(s)
Exon(s)
Protein(s)
Gene
 Accession  3787
 Official symbol  BAK1
 Official name  BCL2-antagonist/killer 1
 Gene type  gene with protein product
 Organism  Homo sapiens
 Location  Chromosome 6 (NC_000006.11) :  33540322...33548069  (-)
 Map  6p21.31
 Length  7748  nt
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Alternative name(s) and Synynom(s) top
Synonyms MGC3887; MGC117255; BAK-LIKE; CDN1; BCL2L7; BAK
Alternative name(s) bCL2-antagonist/killer 1; pro-apoptotic protein BAK; BCL2-like 7 protein; Bcl-2 homologous antagonist/killer; apoptosis regulator BAK
External Links top
Ensembl ENSG00000030110
Entrez 578
HGNC 949
HPRD 02744
Comment top
Summary The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq].
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Genomic Context top
Go to ensembl   www.ensembl.org
Sequence top
FASTA
1  TCTGCATCCG GTGGCCACAG AGCAACTTCC TCTAGAGGGA GCTGATTGGA GCCGGGTGCC GCTGGCACCT CTATGATCAC
81  TGGAGTCTCG CGGGTCCCTC GGGCTGCACA GGGACAAGTA AAGGCTACAT CCAGATGCCG GGAATGCACT GACGCCCATT
161  CCTGGAAACT GGGCTCCCAC TCAGCCCCTG GGAGCAGCAG CCGCCAGCCC CTCGGGACCT CCATCTCCAC CCTGCTGAGC
241  CACCCGGGTT GGGCCAGGAT CCCGGCAGGT AAGCTGGAAG GGTCTTGTCC ATCCTCCCAG ATCTCAGCAG CCCCAGCCCC
321  AGGGTGGGGC AGGGAGCCTG CCGGGAGCCG GGTGGGGAAG GGGAAGCTCA AGGCTTCCCT GGGCAGGTCT GCCGCCCCGG
401  CTGGGGACCT GATCCTGCCA TGCCTGCCTC TGGCTGCCCC TCACAGCTTC CCCTCTTGGC CCAGCCCTGG ATGCCGGAGA
481  ACTGTAAGAA CTGGGTCCTT TAACAGTCTG GGAGATGGGA GTGGAGGTCA GAGCCAAGGT CAAGGGCAGA GAGAGAACTT
561  TCTCAGCGCT TGCTGCTGCC CAACATCCCT AGACTGGGTC CAGGGCCTGG CCAGGCATGT ATCCCTGGGC AACATTCATC
641  GGGGCCCAGC AAGCCCAGGA AGTCGGGGGT GGCTCCCCTC ACCGGGAATT TAGGCCACTT GGATGGGGGA GGCAGAGCTA
721  GGCCTGAGTC AGCATAGGTT GCTGGCCTTG GTGGGTGTTC TGAGGCTCTA CCTGCTCCCC TCGGAAGCCT GGGGTGTTGG
801  TAGAGGGAGT TGGAGGTGCA GTCAGCATCC TCCAGCCCTA CTGTCCTGGG GGTGCCGGGT CCTGGAGACT GGGGAAGAAG
881  GAAGGCCATC TTATGTAAGG AGCTACGGGG GGTGGGAGGC AAGCAAAACT CTTTTTTTTT GTTTTTTGAA ATGGAGTCTC
961  GCTCTGTTGC CCAGGCTGGA GTGCAGTGGC GCAATCTCGG CTGACCGCAA CCTCCGCCTC CAAGGTTCAA GCGATTCTCC
1041  TGCCTCAGCC TCCCGAGTAG CTGGGACTAC AGGCGCACGC CACCATGCCC AGCTAATTTT TGTATTTTTA GTAGAGATGG
1121  GGTTTCATTA TGTTGGCCAA GCTGGTCTTG AACTTCTGAC CTCGTGGGCC ACTATGCCCG GCTGCAAAGT TCTGTTTTAA
1201  CAAGGCCTTG CCCCTAGAGG TGGAGGAGAG GAAGGTCTGC CTTCACCCTG TCCCTGTCCG GCAGATCGAG GAGGAGTGGG
1281  GAGCTGGGTG AGGGCACAGG TGGTCCAGCC CTCCTCCACC CCTTCTTGAG AGCTCTTGGG GCACTTTCGA AAACACTCCC
1361  AGGCCTAGCG GAAGGAGGGT GGGCGAAGGT CCCCAGGCCC TGGGCGGTGG GGGTGGGGCT GTGTGCTTGG CCCAGGGTGG
1441  GGCTGCACAC CCCCTCCCTC TGGGATAGGA GGAGGGCGCT CTCCTTCTGA GGGCTGGAGG CTGCCTGGGG AAATGGGGCT
1521  CTGGGAGGGG TGCAAACTGA AAGTGAAACA GCTGACATCC AGGAAACACT CGCCCTGATG AGGGGTCACA GCAGGTTGGG
1601  GCTGCGGTCA GGACCAGGCA AAGAGGAAAA TTGGGGCCGG GGACAGAAGA CCAGGTGTGT GGTGGGAGTA CGAGGCAGGT
1681  TATGGGGCTT CAAAGAAGGC CCTGATCCTG AGGGCTCCCT CCGGTCACTG CAAGGCAGCA GTGGGGAAGG CACAGACAGG
1761  AGGTAAATAG GGAAAGTTGC CCTGAGAAAG AACACACTCT GAGGTCCACA AACTGGAAAA GAAATCTTGC ATGCGTGTTG
1841  AGTACATGGA CTCACGGAGA TTCAGACAAA CAACCTGACT TTCCGTGACT AACGATGTGA CCTCGGGCAC TCAACTCTTT
1921  GTGCCTCACT TTTCCTGCCT GTAAAGTGGG TATGATGGCG CTCACCCTGC TGGGTTCATG TGAGTTTCCA GTGTTCACCA
2001  CCCACAGAGT GCTCCTAAGT GGGAGAGTAT ATCTTAGGCT CTCAGGAAAT GTTTGCGGCT AACAGCCCAG AGTTAAAAAA
2081  CAGGTGTGTT CTGGCCAGCC AGAGGGAAGT AGGGCCTCTG AGGACAGCCT TCATGGGCCA TTGGCTGGGC AGTGGCTCGC
2161  TTGCAATAAG CATGTGCTGG GTGGGCTGCA GGAGGCCCCA GGAACAGCTA AAAACCCCCC AGGCTCTTGC CCCAGGAGTG
2241  GCATGAACTT GAGAGCCAGC GGGCACTGCT GCAGCCACAC CCTCCTCGAT GGTGCAGATA CCTCAGTCTG CCCTTGGCTG
2321  CCTCACCTTC TTACCCTGTC TCCCTCAAAG AGGGAGTGTT CAGTAAGTTG TTTCCTCCCA GCAGACTTCA CTGGGACCCA
2401  TGCTGGAGTA AGAATAAAAA GTCCCAGAGG AGGCCAGGCA CGGTGGCTCA CACCTGTAAT CCCAGCACTG TGGATGGCCG
2481  AGGCAGACTC ACGAGGTCAG GAGTTTGAGA CCGGCCTGGC CAAAGTCCCA GAGGACTAAG GGCCTTTCTG GGAATGGGGG
2561  ATCCTCTCTC CTATGTGGAC ATGGCAACCT GTATGGGGTC CCCAGTCACA GGTCTGTGCT CACCCCCATC TCTGCTTTTT
2641  CTCGCCCTTC CCCGCAGGCT GATCCCGTCC TCCACTGAGA CCTGAAAAAT GGCTTCGGGG CAAGGCCCAG GTCCTCCCAG
2721  GCAGGAGTGC GGAGAGCCTG CCCTGCCCTC TGCTTCTGGT AAGGGTCTTC CTGCCCCCTC ACCCATCCCA TAACCATGAG
2801  TGCTGTCGTG AGGATGGAAG GAGCAGGACT CAGGCAGGCT CCTTCGCCTC GGTTCACCCA CTGTGGGTGG GGAATACTCT
2881  TCCCCACCCA CGGGCTCAGA GGCTGGAGCT GCTGTCAAGG TTAAGCCCAG GAGGGGGAGG AGTCTGGACT GGGGAGGGCC
2961  TGGAGGTTGG GAGAGGCCAG GAAGTGAGTG TAAGGTAGGC ACAGTGCCAC CGGGGCAGAG GGCTGGGTCA CGGGCGAGGG
3041  AGGCAGGAAT TAGAGTGGGG CCTGGCTGCT GTATCCCTCC AGCGGGAGAA ATAAGGAAGT AAGCTGGCCA ATCACCCAGT
3121  CAGGTCTGCT CAACAGGGAA CGCAATTATT GTGACTTGGG GAGGAAGTAA GATGGCTGCC CTCCTTCCCT CTTCCCAGGG
3201  GATAGCCAGG GAAGCCCCAG CTCACACCTC ACGGCGGGCT GTTCCCTGGA CTTGGGAATC AGGTCCCAGG TCTGTCACTA
3281  TCTCCCTGTG TGACTTTTCT GGGCCGCAGC TACAAATTCA GATTTTGTTT CCCACATTTC CCTGCACGCA AAGGGCTGCG
3361  GAGCTGAGAT GTACTAATGT AGACTCAGGA CCCCAAATGC CCGGGACTGT CCCGGTTCCC CGGCTTGTTC TGGCTGTATG
3441  ACCTTGCACA CGTTACTCAG ACACCCTGTG CCATTTTCCC CCTGCCAGCT GGGGATTGCC TGCTCCCAGG GCTACTGTGA
3521  GGACTCAATG CAAGTGCCGG AACAACTCTC CACACAGCAT AAGCTCTAGG GGCGGCTAAG GTGCTGAAGT AGGGATATTT
3601  CTTTTCTTTT TTTTTTTTTT GTTTTTTTTG TTGTTGTTGT TTTGTTTTGT TTTGTTTTTT GAGATGGAGT CTCGCTCTAT
3681  TGCCCAGGCT GGAGTGCAGT GGCGTGATCT AGGCTCACTG CAAGCTCCAA CTCCCGGGTT CACGCCATTC TCCTGCCTCA
3761  GCCTCCCGAG TAGCTGGGAC TACAGGCGCC TCCCACCACG CCTGGCTAAT TTTTTGTATT TTGTTTAGTA GAGACGGGGT
3841  TTCACCATGT TAGCCAGGAT GGTCTCAATC TCCTGACCTC GTGATCCGCC CGCCTTGGCC TCCCAAAGTG CTGGGATTAC
3921  AGGCATGAGC CACCACACCC GGCCATTTTT TTTTTTTTTT TGAGACAGAG TTTCGCTCTT GTTGCCTAGG CTGGAGTGCA
4001  GTGGCACGAT CTCCGCTCAC CGCAACCTCC GCCTCCCGGG GTCAAGTAAT TCTCCTGCCT CAGCCTCTTC TTGAGTAGGT
4081  GGGATTACAG GCATGTGCCA CCACACCCGG CTAATTTTGT ATTTTTAGTA GAGACAGAGT TTCTCCATGT TGGTCAGGCT
4161  GGTCTTGAAC TCCCGACCTC AGGTGATCTG CCCACCTCGG CCTCCCAAAG TGCTGGGATT ATAGGCGTGA GCCACCGCAC
4241  CTGGTTGGGA TATTTCTTTC CATGGGTGAG GACAGCTATG GCCTTAGGAA GAGTGAATCC CCTATAAGGC ATGGGGCTGC
4321  CAGGGTTCGG CCCTCTCTCC CTGACTCCCA GCTTTGATCC TCAGAGGAGC AGGTAGCCCA GGACACAGAG GAGGTTTTCC
4401  GCAGCTACGT TTTTTACCGC CATCAGCAGG AACAGGAGGC TGAAGGGGTG GCTGCCCCTG CCGACCCAGA GATGGTCACC
4481  TTACCTCTGC AACCTAGCAG GTGAGCTACA ACCGCTGGGC CCACAAGGAC ATCTTCAGGG AGGCAGTAGC TCGCATGGGT
4561  CTCTGTGCAG GTCCTGGGAG CTGGGGAGGC CTCGGGGGTC TTGCCCTTCT CTCATGGTTG CTCCTCTTTT ATGTTGGGCT
4641  CCCACCCCCA TCCAGGACCT TGTATCCTTT TTAGCCCATG CCTGCCCCTT CTCCTGGAGC CCAGCACTCA TGTCTTAGAA
4721  CACTGTCAGG GACCTCCAAG AAGGGATGCA CAGGGCCATG GACAGCTCAG GCAGAACCCC TCTGCCATGA GCCAGGGCCT
4801  GGTCCCGACT GCCTGGTTAC TGGCTCACCT GCATGCCTCC TGCTCCTACA GCACCATGGG GCAGGTGGGA CGGCAGCTCG
4881  CCATCATCGG GGACGACATC AACCGACGCT ATGACTCAGA GTTCCAGACC ATGTTGCAGC ACCTGCAGCC CACGGCAGAG
4961  AATGCCTATG AGTACTTCAC CAAGATTGCC ACCAGGTACC CCAGCCACCT CCCTGCCAGC TCCAGTCACT CCTCTGTCAT
5041  GTCACAACCA TACCATACCC TGCCTGCATG ATGCTCTCCT GGCATGGGGA GAAGCCTTCT GTCAGTGTCC AATGTCTGCT
5121  GTGAACTCAC ATGTGGTCTC GGCCCCCTAT TTTTCTCTTT CGGGGTCCCA GACTTGTATT TTGGGCATTA GCTCACAGCT
5201  CTTTTGAGCT CTGACTCCAA GGTCTTGACT GGTTAGATCA GGACTCTAGA GGGGGCCTGA GGTGGGGACG TCCCCCACAG
5281  CTCCCCAGCC CAGCTGGGAC ATAGCTGTCC TTCATAGTTC CAATTTGAAA CCACATATCA CACTGAAGAT GGTGAGGGTG
5361  CTAACCTCTG CCAGGTCCTA GAAATGGCTC CTACTTGCTA TAATCTGGCA TCCAAGTGGT TAAAGACACC GAATATTTGG
5441  GTGCAAATCC AAGCTTTGCC ACTTACTGCC TTCGTGAAGC TTCCTAGCCC TTAGTCTCCT GGTTTGTAAA ATAGGGAAAA
5521  TATGCTTAGA TTAGTGTCCA CCTTACAAAG TGTTAGCCAT TGCTACCACC AGAGTTAGGG AAGTCAGTGT CGGAGTAGAT
5601  TTGAAACTGG AGGTGAAGGT AGGAGTAAGT GATAGATTTT AGAATTAGTG CTCAGAGCTG AAATATCCAG TCCGTGAACT
5681  TAGAGGCCAG CCTTCATACC ACTGTGATGA CAGGAACTAC CCTAATCTTT TCTGTCCTTT TCTCTCTGCT GTCCCTCGGG
5761  CTGCCAGGCC AGCAGCAACA CCCACAGGTA ATCTCCCCGC TGACTCCATC CACTTGCTCT GCCCTCTGCC CTCTCTGTGC
5841  CCCGTTGCAC CTGAGCGTAC ACCCCAGCAG TGGCATCCAG CTCATCTGCC CCTGAGCTTT CTCCTTTCGC AGAGACCCAG
5921  GTTGTTCCCA AATACAGGCC AGGTTGGGGC AGCCTCTGCG GCCTTAATTC ACAGCTAAGC TATTTAGCTT CCAGCTGGGA
6001  GAGGGGTGGG AGAGGCCAGG CAGGCTGAAG GGCTTCCTGG GGGCTCTCCA CCAATGCTAT GGGATGCTCT GCCCACAGCC
6081  TGTTTGAGAG TGGCATCAAT TGGGGCCGTG TGGTGGCTCT TCTGGGCTTC GGCTACCGTC TGGCCCTACA CGTCTACCAG
6161  CATGGCCTGA CTGGCTTCCT AGGCCAGGTG ACCCGCTTCG TGGTCGACTT CATGCTGCAT CACTGCATTG CCCGGTGGAT
6241  TGCACAGAGG GGTGGCTGGG TGAGTATCCA AGGACTGCAA TGTCCTCCCT GCTGTTGGGG CTGCCCCTCT CCCAGGCCCC
6321  ACCCCTTCCT CGGGTTCCTA TATCTTCTGC TAGCCTCTCT GTGACCACCT TGTTTCTCCC GGCAGGTGGC AGCCCTGAAC
6401  TTGGGCAATG GTCCCATCCT GAACGTGCTG GTGGTTCTGG GTGTGGTTCT GTTGGGCCAG TTTGTGGTAC GAAGATTCTT
6481  CAAATCATGA CTCCCAAGGG TGCCCTTTGG GGTCCCGGTT CAGACCCCTG CCTGGACTTA AGCGAAGTCT TTGCCTTCTC
6561  TGTTCCCTTG CAGGGGTCCC CCCTCAAGAG TACAGAAGCT TTAGCAAGTG TGCACTCCAG CTTCGGAGGG CCCCTGCGTG
6641  GGGGCCAGTC AGGCTGCAGA GGCACCTCAA CATTGCATGG TGCTAGTGGG CCCTCTCTCT GGGCCCAGGG GCTGTGGCCG
6721  TCTCCTCCCT CAGCTCTCTG GGACCTCCTT AGCCCTGTCT GCTAGGCGCT GGGGAGACTG ATAACTTGGG GAGGCAAGAG
6801  ACTGGGAGCC ACTTCTCCCC AGAAAGTGTT TAACGGTTTT AGCTTTTTAT AATACCCTTG TGAGAGCCCA TTCCCACCAT
6881  TCTACCTGAG GCCAGGACGT CTGGGGTGTG GGGATTGGTG GGTCTATGTT CCCCAGGATT CAGCTATTCT GGAAGATCAG
6961  CACCCTAAGA GATGGGACTA GGACCTGAGC CTGGTCCTGG CCGTCCCTAA GCATGTGTCC CAGGAGCAGG ACCTACTAGG
7041  AGAGGGGGGC CAAGGTCCTG CTCAACTCTA CCCCTGCTCC CATTCCTCCC TCCGGCCATA CTGCCTTTGC AGTTGGACTC
7121  TCAGGGATTC TGGGCTTGGG GTGTGGGGTG GGGTGGAGTC GCAGACCAGA GCTGTCTGAA CTCACGTGTC AGAAGCCTCC
7201  AAGCCTGCCT CCCAAGGTCC TCTCAGTTCT CTCCCTTCCT CTCTCCTTAT AGACACTTGC TCCCAACCCA TTCACTACAG
7281  GTGAAGGCTC TCACCCCCAT CCCTGGGGGC CTTGGGTGAG TGGCCTGCTA AGGCTCCTCC TTGCCCAGAC TACAGGGCTT
7361  AGGACTTGGT TTGTTATATC AGGGAAAAGG AGTAGGGAGT TCATCTGGAG GGTTCTAAGT GGGAGAAGGA CTATCAACAC
7441  CACTAGGAAT CCCAGAGGTG GGATCCTCCC TCATGGCTCT GGCACAGTGT AATCCAGGGG TGTAGATGGG GGAACTGTGA
7521  ATACTTGAAC TCTGTTCCCC CACCCTCCAT GCTCCTCACC TGTCTAGGTC TCCTCAGGGT GGGGGGTGAC AGTGCCTTCT
7601  CTATTGGGCA CAGCCTAGGG TCTTGGGGGT CAGGGGGGAG AAGTTCTTGA TTCAGCCAAA TGCAGGGAGG GGAGGCAGAT
7681  GGAGCCCATA GGCCACCCCC TATCCTCTGA GTGTTTGGAA ATAAACTGTG CAATCCCCTC ACCCTGAC
>ref|Gene_ID:578|BAK1|NC_000006.11:33540322...33548069 (-)
TCTGCATCCGGTGGCCACAGAGCAACTTCCTCTAGAGGGAGCTGATTGGAGCCGGGTGCCGCTGGCACCTCTATGATCAC
TGGAGTCTCGCGGGTCCCTCGGGCTGCACAGGGACAAGTAAAGGCTACATCCAGATGCCGGGAATGCACTGACGCCCATT
CCTGGAAACTGGGCTCCCACTCAGCCCCTGGGAGCAGCAGCCGCCAGCCCCTCGGGACCTCCATCTCCACCCTGCTGAGC
CACCCGGGTTGGGCCAGGATCCCGGCAGGTAAGCTGGAAGGGTCTTGTCCATCCTCCCAGATCTCAGCAGCCCCAGCCCC
AGGGTGGGGCAGGGAGCCTGCCGGGAGCCGGGTGGGGAAGGGGAAGCTCAAGGCTTCCCTGGGCAGGTCTGCCGCCCCGG
CTGGGGACCTGATCCTGCCATGCCTGCCTCTGGCTGCCCCTCACAGCTTCCCCTCTTGGCCCAGCCCTGGATGCCGGAGA
ACTGTAAGAACTGGGTCCTTTAACAGTCTGGGAGATGGGAGTGGAGGTCAGAGCCAAGGTCAAGGGCAGAGAGAGAACTT
TCTCAGCGCTTGCTGCTGCCCAACATCCCTAGACTGGGTCCAGGGCCTGGCCAGGCATGTATCCCTGGGCAACATTCATC
GGGGCCCAGCAAGCCCAGGAAGTCGGGGGTGGCTCCCCTCACCGGGAATTTAGGCCACTTGGATGGGGGAGGCAGAGCTA
GGCCTGAGTCAGCATAGGTTGCTGGCCTTGGTGGGTGTTCTGAGGCTCTACCTGCTCCCCTCGGAAGCCTGGGGTGTTGG
TAGAGGGAGTTGGAGGTGCAGTCAGCATCCTCCAGCCCTACTGTCCTGGGGGTGCCGGGTCCTGGAGACTGGGGAAGAAG
GAAGGCCATCTTATGTAAGGAGCTACGGGGGGTGGGAGGCAAGCAAAACTCTTTTTTTTTGTTTTTTGAAATGGAGTCTC
GCTCTGTTGCCCAGGCTGGAGTGCAGTGGCGCAATCTCGGCTGACCGCAACCTCCGCCTCCAAGGTTCAAGCGATTCTCC
TGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCACGCCACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGATGG
GGTTTCATTATGTTGGCCAAGCTGGTCTTGAACTTCTGACCTCGTGGGCCACTATGCCCGGCTGCAAAGTTCTGTTTTAA
CAAGGCCTTGCCCCTAGAGGTGGAGGAGAGGAAGGTCTGCCTTCACCCTGTCCCTGTCCGGCAGATCGAGGAGGAGTGGG
GAGCTGGGTGAGGGCACAGGTGGTCCAGCCCTCCTCCACCCCTTCTTGAGAGCTCTTGGGGCACTTTCGAAAACACTCCC
AGGCCTAGCGGAAGGAGGGTGGGCGAAGGTCCCCAGGCCCTGGGCGGTGGGGGTGGGGCTGTGTGCTTGGCCCAGGGTGG
GGCTGCACACCCCCTCCCTCTGGGATAGGAGGAGGGCGCTCTCCTTCTGAGGGCTGGAGGCTGCCTGGGGAAATGGGGCT
CTGGGAGGGGTGCAAACTGAAAGTGAAACAGCTGACATCCAGGAAACACTCGCCCTGATGAGGGGTCACAGCAGGTTGGG
GCTGCGGTCAGGACCAGGCAAAGAGGAAAATTGGGGCCGGGGACAGAAGACCAGGTGTGTGGTGGGAGTACGAGGCAGGT
TATGGGGCTTCAAAGAAGGCCCTGATCCTGAGGGCTCCCTCCGGTCACTGCAAGGCAGCAGTGGGGAAGGCACAGACAGG
AGGTAAATAGGGAAAGTTGCCCTGAGAAAGAACACACTCTGAGGTCCACAAACTGGAAAAGAAATCTTGCATGCGTGTTG
AGTACATGGACTCACGGAGATTCAGACAAACAACCTGACTTTCCGTGACTAACGATGTGACCTCGGGCACTCAACTCTTT
GTGCCTCACTTTTCCTGCCTGTAAAGTGGGTATGATGGCGCTCACCCTGCTGGGTTCATGTGAGTTTCCAGTGTTCACCA
CCCACAGAGTGCTCCTAAGTGGGAGAGTATATCTTAGGCTCTCAGGAAATGTTTGCGGCTAACAGCCCAGAGTTAAAAAA
CAGGTGTGTTCTGGCCAGCCAGAGGGAAGTAGGGCCTCTGAGGACAGCCTTCATGGGCCATTGGCTGGGCAGTGGCTCGC
TTGCAATAAGCATGTGCTGGGTGGGCTGCAGGAGGCCCCAGGAACAGCTAAAAACCCCCCAGGCTCTTGCCCCAGGAGTG
GCATGAACTTGAGAGCCAGCGGGCACTGCTGCAGCCACACCCTCCTCGATGGTGCAGATACCTCAGTCTGCCCTTGGCTG
CCTCACCTTCTTACCCTGTCTCCCTCAAAGAGGGAGTGTTCAGTAAGTTGTTTCCTCCCAGCAGACTTCACTGGGACCCA
TGCTGGAGTAAGAATAAAAAGTCCCAGAGGAGGCCAGGCACGGTGGCTCACACCTGTAATCCCAGCACTGTGGATGGCCG
AGGCAGACTCACGAGGTCAGGAGTTTGAGACCGGCCTGGCCAAAGTCCCAGAGGACTAAGGGCCTTTCTGGGAATGGGGG
ATCCTCTCTCCTATGTGGACATGGCAACCTGTATGGGGTCCCCAGTCACAGGTCTGTGCTCACCCCCATCTCTGCTTTTT
CTCGCCCTTCCCCGCAGGCTGATCCCGTCCTCCACTGAGACCTGAAAAATGGCTTCGGGGCAAGGCCCAGGTCCTCCCAG
GCAGGAGTGCGGAGAGCCTGCCCTGCCCTCTGCTTCTGGTAAGGGTCTTCCTGCCCCCTCACCCATCCCATAACCATGAG
TGCTGTCGTGAGGATGGAAGGAGCAGGACTCAGGCAGGCTCCTTCGCCTCGGTTCACCCACTGTGGGTGGGGAATACTCT
TCCCCACCCACGGGCTCAGAGGCTGGAGCTGCTGTCAAGGTTAAGCCCAGGAGGGGGAGGAGTCTGGACTGGGGAGGGCC
TGGAGGTTGGGAGAGGCCAGGAAGTGAGTGTAAGGTAGGCACAGTGCCACCGGGGCAGAGGGCTGGGTCACGGGCGAGGG
AGGCAGGAATTAGAGTGGGGCCTGGCTGCTGTATCCCTCCAGCGGGAGAAATAAGGAAGTAAGCTGGCCAATCACCCAGT
CAGGTCTGCTCAACAGGGAACGCAATTATTGTGACTTGGGGAGGAAGTAAGATGGCTGCCCTCCTTCCCTCTTCCCAGGG
GATAGCCAGGGAAGCCCCAGCTCACACCTCACGGCGGGCTGTTCCCTGGACTTGGGAATCAGGTCCCAGGTCTGTCACTA
TCTCCCTGTGTGACTTTTCTGGGCCGCAGCTACAAATTCAGATTTTGTTTCCCACATTTCCCTGCACGCAAAGGGCTGCG
GAGCTGAGATGTACTAATGTAGACTCAGGACCCCAAATGCCCGGGACTGTCCCGGTTCCCCGGCTTGTTCTGGCTGTATG
ACCTTGCACACGTTACTCAGACACCCTGTGCCATTTTCCCCCTGCCAGCTGGGGATTGCCTGCTCCCAGGGCTACTGTGA
GGACTCAATGCAAGTGCCGGAACAACTCTCCACACAGCATAAGCTCTAGGGGCGGCTAAGGTGCTGAAGTAGGGATATTT
CTTTTCTTTTTTTTTTTTTTGTTTTTTTTGTTGTTGTTGTTTTGTTTTGTTTTGTTTTTTGAGATGGAGTCTCGCTCTAT
TGCCCAGGCTGGAGTGCAGTGGCGTGATCTAGGCTCACTGCAAGCTCCAACTCCCGGGTTCACGCCATTCTCCTGCCTCA
GCCTCCCGAGTAGCTGGGACTACAGGCGCCTCCCACCACGCCTGGCTAATTTTTTGTATTTTGTTTAGTAGAGACGGGGT
TTCACCATGTTAGCCAGGATGGTCTCAATCTCCTGACCTCGTGATCCGCCCGCCTTGGCCTCCCAAAGTGCTGGGATTAC
AGGCATGAGCCACCACACCCGGCCATTTTTTTTTTTTTTTTGAGACAGAGTTTCGCTCTTGTTGCCTAGGCTGGAGTGCA
GTGGCACGATCTCCGCTCACCGCAACCTCCGCCTCCCGGGGTCAAGTAATTCTCCTGCCTCAGCCTCTTCTTGAGTAGGT
GGGATTACAGGCATGTGCCACCACACCCGGCTAATTTTGTATTTTTAGTAGAGACAGAGTTTCTCCATGTTGGTCAGGCT
GGTCTTGAACTCCCGACCTCAGGTGATCTGCCCACCTCGGCCTCCCAAAGTGCTGGGATTATAGGCGTGAGCCACCGCAC
CTGGTTGGGATATTTCTTTCCATGGGTGAGGACAGCTATGGCCTTAGGAAGAGTGAATCCCCTATAAGGCATGGGGCTGC
CAGGGTTCGGCCCTCTCTCCCTGACTCCCAGCTTTGATCCTCAGAGGAGCAGGTAGCCCAGGACACAGAGGAGGTTTTCC
GCAGCTACGTTTTTTACCGCCATCAGCAGGAACAGGAGGCTGAAGGGGTGGCTGCCCCTGCCGACCCAGAGATGGTCACC
TTACCTCTGCAACCTAGCAGGTGAGCTACAACCGCTGGGCCCACAAGGACATCTTCAGGGAGGCAGTAGCTCGCATGGGT
CTCTGTGCAGGTCCTGGGAGCTGGGGAGGCCTCGGGGGTCTTGCCCTTCTCTCATGGTTGCTCCTCTTTTATGTTGGGCT
CCCACCCCCATCCAGGACCTTGTATCCTTTTTAGCCCATGCCTGCCCCTTCTCCTGGAGCCCAGCACTCATGTCTTAGAA
CACTGTCAGGGACCTCCAAGAAGGGATGCACAGGGCCATGGACAGCTCAGGCAGAACCCCTCTGCCATGAGCCAGGGCCT
GGTCCCGACTGCCTGGTTACTGGCTCACCTGCATGCCTCCTGCTCCTACAGCACCATGGGGCAGGTGGGACGGCAGCTCG
CCATCATCGGGGACGACATCAACCGACGCTATGACTCAGAGTTCCAGACCATGTTGCAGCACCTGCAGCCCACGGCAGAG
AATGCCTATGAGTACTTCACCAAGATTGCCACCAGGTACCCCAGCCACCTCCCTGCCAGCTCCAGTCACTCCTCTGTCAT
GTCACAACCATACCATACCCTGCCTGCATGATGCTCTCCTGGCATGGGGAGAAGCCTTCTGTCAGTGTCCAATGTCTGCT
GTGAACTCACATGTGGTCTCGGCCCCCTATTTTTCTCTTTCGGGGTCCCAGACTTGTATTTTGGGCATTAGCTCACAGCT
CTTTTGAGCTCTGACTCCAAGGTCTTGACTGGTTAGATCAGGACTCTAGAGGGGGCCTGAGGTGGGGACGTCCCCCACAG
CTCCCCAGCCCAGCTGGGACATAGCTGTCCTTCATAGTTCCAATTTGAAACCACATATCACACTGAAGATGGTGAGGGTG
CTAACCTCTGCCAGGTCCTAGAAATGGCTCCTACTTGCTATAATCTGGCATCCAAGTGGTTAAAGACACCGAATATTTGG
GTGCAAATCCAAGCTTTGCCACTTACTGCCTTCGTGAAGCTTCCTAGCCCTTAGTCTCCTGGTTTGTAAAATAGGGAAAA
TATGCTTAGATTAGTGTCCACCTTACAAAGTGTTAGCCATTGCTACCACCAGAGTTAGGGAAGTCAGTGTCGGAGTAGAT
TTGAAACTGGAGGTGAAGGTAGGAGTAAGTGATAGATTTTAGAATTAGTGCTCAGAGCTGAAATATCCAGTCCGTGAACT
TAGAGGCCAGCCTTCATACCACTGTGATGACAGGAACTACCCTAATCTTTTCTGTCCTTTTCTCTCTGCTGTCCCTCGGG
CTGCCAGGCCAGCAGCAACACCCACAGGTAATCTCCCCGCTGACTCCATCCACTTGCTCTGCCCTCTGCCCTCTCTGTGC
CCCGTTGCACCTGAGCGTACACCCCAGCAGTGGCATCCAGCTCATCTGCCCCTGAGCTTTCTCCTTTCGCAGAGACCCAG
GTTGTTCCCAAATACAGGCCAGGTTGGGGCAGCCTCTGCGGCCTTAATTCACAGCTAAGCTATTTAGCTTCCAGCTGGGA
GAGGGGTGGGAGAGGCCAGGCAGGCTGAAGGGCTTCCTGGGGGCTCTCCACCAATGCTATGGGATGCTCTGCCCACAGCC
TGTTTGAGAGTGGCATCAATTGGGGCCGTGTGGTGGCTCTTCTGGGCTTCGGCTACCGTCTGGCCCTACACGTCTACCAG
CATGGCCTGACTGGCTTCCTAGGCCAGGTGACCCGCTTCGTGGTCGACTTCATGCTGCATCACTGCATTGCCCGGTGGAT
TGCACAGAGGGGTGGCTGGGTGAGTATCCAAGGACTGCAATGTCCTCCCTGCTGTTGGGGCTGCCCCTCTCCCAGGCCCC
ACCCCTTCCTCGGGTTCCTATATCTTCTGCTAGCCTCTCTGTGACCACCTTGTTTCTCCCGGCAGGTGGCAGCCCTGAAC
TTGGGCAATGGTCCCATCCTGAACGTGCTGGTGGTTCTGGGTGTGGTTCTGTTGGGCCAGTTTGTGGTACGAAGATTCTT
CAAATCATGACTCCCAAGGGTGCCCTTTGGGGTCCCGGTTCAGACCCCTGCCTGGACTTAAGCGAAGTCTTTGCCTTCTC
TGTTCCCTTGCAGGGGTCCCCCCTCAAGAGTACAGAAGCTTTAGCAAGTGTGCACTCCAGCTTCGGAGGGCCCCTGCGTG
GGGGCCAGTCAGGCTGCAGAGGCACCTCAACATTGCATGGTGCTAGTGGGCCCTCTCTCTGGGCCCAGGGGCTGTGGCCG
TCTCCTCCCTCAGCTCTCTGGGACCTCCTTAGCCCTGTCTGCTAGGCGCTGGGGAGACTGATAACTTGGGGAGGCAAGAG
ACTGGGAGCCACTTCTCCCCAGAAAGTGTTTAACGGTTTTAGCTTTTTATAATACCCTTGTGAGAGCCCATTCCCACCAT
TCTACCTGAGGCCAGGACGTCTGGGGTGTGGGGATTGGTGGGTCTATGTTCCCCAGGATTCAGCTATTCTGGAAGATCAG
CACCCTAAGAGATGGGACTAGGACCTGAGCCTGGTCCTGGCCGTCCCTAAGCATGTGTCCCAGGAGCAGGACCTACTAGG
AGAGGGGGGCCAAGGTCCTGCTCAACTCTACCCCTGCTCCCATTCCTCCCTCCGGCCATACTGCCTTTGCAGTTGGACTC
TCAGGGATTCTGGGCTTGGGGTGTGGGGTGGGGTGGAGTCGCAGACCAGAGCTGTCTGAACTCACGTGTCAGAAGCCTCC
AAGCCTGCCTCCCAAGGTCCTCTCAGTTCTCTCCCTTCCTCTCTCCTTATAGACACTTGCTCCCAACCCATTCACTACAG
GTGAAGGCTCTCACCCCCATCCCTGGGGGCCTTGGGTGAGTGGCCTGCTAAGGCTCCTCCTTGCCCAGACTACAGGGCTT
AGGACTTGGTTTGTTATATCAGGGAAAAGGAGTAGGGAGTTCATCTGGAGGGTTCTAAGTGGGAGAAGGACTATCAACAC
CACTAGGAATCCCAGAGGTGGGATCCTCCCTCATGGCTCTGGCACAGTGTAATCCAGGGGTGTAGATGGGGGAACTGTGA
ATACTTGAACTCTGTTCCCCCACCCTCCATGCTCCTCACCTGTCTAGGTCTCCTCAGGGTGGGGGGTGACAGTGCCTTCT
CTATTGGGCACAGCCTAGGGTCTTGGGGGTCAGGGGGGAGAAGTTCTTGATTCAGCCAAATGCAGGGAGGGGAGGCAGAT
GGAGCCCATAGGCCACCCCCTATCCTCTGAGTGTTTGGAAATAAACTGTGCAATCCCCTCACCCTGAC