(STK11) serine/threonine kinase 11 [Homo sapiens] |
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Gene
Transcript(s)
Exon(s)
Protein(s)
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Accession
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10213
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Official symbol
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STK11
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Official name
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serine/threonine kinase 11
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Gene type
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gene with protein product
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Organism
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Homo sapiens
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Location
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Chromosome 19 (NC_000019.9) : 1205797...1228433 (+)
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Map
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19p13.3
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Length
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22637 nt
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NM_000455.4
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STK11, mRNA isoform 1
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Accession
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Name
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Organism
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Length
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Q15831
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Serine/threonine-protein kinase 11
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Homo sapiens
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433 aa
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Synonyms |
PJS; LKB1
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Alternative name(s) |
serine/threonine kinase 11 (Peutz-Jeghers syndrome); polarization-related protein LKB1
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Summary |
This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq].
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Related Articles in PubMed
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Go to ensembl
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1 |
GGCGTGTCGG |
GCGCGGAAGG |
GGGAGGCGGC |
CCGGGGCGCC |
CGCGAGTGAG |
GCGCGGGGCG |
GCGAAGGGAG |
CGCGGGTGGC |
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81 |
GGCACTTGCT |
GCCGCGGCCT |
TGGATGGGCT |
GGGCCCCCCT |
CGCCGCTCCG |
CCTCCTCCAC |
ACGCGCGGCG |
GCCGCGGCGA |
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161 |
GGGGGACGCG |
CCGCCCGGGG |
CCCGGCACCT |
TCGGGAACCC |
CCCGGCCCGG |
AGCCTGCGGC |
CTGCGCCGCC |
TCGGCCGCCG |
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241 |
GGAGCCCCGT |
GGAGCCCCCG |
CCGCCGCGCC |
GCCCCGCGGA |
CCGGACGCTG |
AGGGCACTCG |
GGGCGGGGCG |
CGCGCTCGGG |
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321 |
CAGACGTTTG |
CGGGGAGGGG |
GGCGCCTGCC |
GGGCCCCGGC |
GACCACCTTG |
GGGGTCGCGG |
GCCGGCTCGG |
GGGGCGCCCA |
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401 |
GTGCGGGCCC |
TCGCGGGCGC |
CGGGCAGCGA |
CCAGCCCTGA |
GCGGAGCTGT |
TGGCCGCGGC |
GGGAGGCCTC |
CCGGACGCCC |
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481 |
CCAGCCCCCC |
GAACGCTCGC |
CCGGGCCGGC |
GGGAGTCGGC |
GCCCCCCGGG |
AGGTCCGCTC |
GGTCGTCCGC |
GGCGGAGCGT |
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561 |
TTGCTCCTGG |
GACAGGCGGT |
GGGACCGGGG |
CGTCGCCGGA |
GACGCCCCCA |
GCGAAGTTGG |
GCTCTCCAGG |
TGTGGGGGTC |
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641 |
CCGGGGGGTA |
GCGACGTCGC |
GGACCCGGCC |
TGTGGGATGG |
GCGGCCCGGA |
GAAGACTGCG |
CTCGGCCGTG |
TTCATACTTG |
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721 |
TCCGTGGGCC |
TGAGGTCCCC |
GGAGGATGAC |
CTAGCACTGA |
AAAGCCCCGG |
CCGGCCTCCC |
CAGGGTCCCC |
GAGGACGAAG |
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801 |
TTGACCCTGA |
CCGGGCCGTC |
TCCCAGTTCT |
GAGGCCCGGG |
TCCCACTGGA |
ACTCGCGTCT |
GAGCCGCCGT |
CCCGGACCCC |
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881 |
CGGTGCCCGC |
CGGTCCGCAG |
ACCCTGCACC |
GGGCTTGGAC |
TCGCAGCCGG |
GACTGACGTG |
TAGAACAATC |
GTTTCTGTTG |
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961 |
GAAGAAGGGT |
TTTTCCCTTC |
CTTTTGGGGT |
TTTTGTTGCC |
TTTTTTTTTT |
CTTTTTTCTT |
TGTAAAATTT |
TGGAGAAGGG |
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1041 |
AAGTCGGAAC |
ACAAGGAAGG |
ACCGCTCACC |
CGCGGACTCA |
GGGCTGGCGG |
CGGGACTCCA |
GGACCCTGGG |
TCCAGCATGG |
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1121 |
AGGTGGTGGA |
CCCGCAGCAG |
CTGGGCATGT |
TCACGGAGGG |
CGAGCTGATG |
TCGGTGGGTA |
TGGACACGTT |
CATCCACCGC |
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1201 |
ATCGACTCCA |
CCGAGGTCAT |
CTACCAGCCG |
CGCCGCAAGC |
GGGCCAAGCT |
CATCGGCAAG |
TACCTGATGG |
GGGACCTGCT |
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1281 |
GGGGGAAGGC |
TCTTACGGCA |
AGGTGAAGGA |
GGTGCTGGAC |
TCGGAGACGC |
TGTGCAGGAG |
GGCCGTCAAG |
ATCCTCAAGA |
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1361 |
AGAAGAAGTT |
GCGAAGGATC |
CCCAACGGGG |
AGGCCAACGT |
GAAGAAGTAA |
GTATGGCTTG |
CTGGGGTCGG |
GGCCGGGCCG |
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1441 |
GGCCAGTCAC |
GGTGCTGATG |
GTTCTGTCTT |
CCTTCCTTCT |
CTCCTCCCTC |
CCTCCCTTAC |
TTCCTCTTAA |
CACCCTGAGC |
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1521 |
TGGACCCGTC |
TGGCGCCTGT |
GTCCTCCGTG |
CCAGGGAGAG |
CGTGGTTGGG |
GGCCTGCGTT |
ACGGACTTTC |
ACTCAGGCAA |
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1601 |
GGCCAGTTGT |
CGCAGCGGGG |
CGTGCGTTTG |
CATGGGCTCT |
TGGACTCCAG |
TTAAAATGCC |
CTGGTAGCGA |
AACCCTCCTG |
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1681 |
AGAAGGGAGC |
GGCCCCCAAT |
CCCCTAAGAC |
TAGCCCCTTG |
GCTCCCCCAG |
CTGTCCAAGG |
AGCAGAGGCG |
CCCAGTGGAA |
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1761 |
TCAGCCTGTG |
TTTGTTTGGG |
CCCCGAGAGT |
TTGTGTGCGG |
CCGCCAACAC |
GTTTTCTGCG |
CAGTGTGTGG |
CCGTTACCGG |
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1841 |
GGCCAGGCGA |
AATGTGATTT |
GTTTATCCTG |
TCAGAGGGGA |
ACCCTGGGCT |
GCCAAAAATA |
ACTGTTTGCA |
CCGGCTTATC |
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1921 |
AGTCAGCAGG |
AGGGAAACGT |
AGCCTTTCCT |
CATTTGCCAG |
GGATGTGACG |
CTGGAAGCAT |
CCCTGGCCCC |
CGGGGCTGGA |
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2001 |
AGCCCTGCCC |
GAGGGGGACT |
GTGCCTCCCT |
CCCGAATTGC |
ATCCGGAAGA |
CCTTACTTTT |
CCAACTGACT |
TCTTCAGGCA |
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2081 |
CGGGGCTGCC |
GCTGGGCATC |
CCGGACGCCT |
CTGCATCTGT |
GCGCGGAGAA |
GCTCCTACCT |
AGGGCAGCAC |
TGGCCGGCCT |
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2161 |
GAGCCTCTCC |
CAGCTGGTGG |
GGGTGGCCGG |
GGGTGTCCCT |
GCCTTATCGC |
AGCCAGACAC |
GCTGCACCTG |
CCGCCGCCTG |
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2241 |
GCGGGCCCTG |
CCCAGGCCCT |
GCTCCTTTCC |
CAGCCTTCTT |
AACTTTCAAA |
ACTTTGCCTC |
CTGTTTCCAA |
GAAAGGACCT |
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2321 |
TATCTGCTGG |
GCTAGGCCTC |
GAGGGACTGG |
CAAGGACACC |
CTGCGCAGGG |
CACCATGACC |
TTGGAAGGAG |
GTCCGGGGAG |
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2401 |
GGGCTGCTGC |
GGTGTCTGCT |
CTCACCTTCC |
TCCTGCTCAG |
GGGCCCTGGG |
GCTCCTGCCG |
TGTCTGCTCT |
CACCTCTCTC |
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2481 |
CTGCTCAGGG |
GCCCTGGGGC |
TCACGTACAT |
TTTTTTTTTT |
TTTTTTTTGA |
GACGGAGTCT |
CGCTCTGTTC |
CCCAGGCTGG |
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2561 |
AGTGCAGTGG |
CGCGAACTGG |
GCTCACTGCA |
AGCTCCGCCT |
CCCGGGTTCA |
TGCCATTCTC |
CTGCCTCAGC |
CTCCCGAGTA |
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2641 |
GCTGGGACTA |
CAGGCACCCG |
CCACCACGCC |
CGGCCAATTT |
TTTGTATTTT |
TCAGTAGAGA |
CGGGGTTTCA |
CCGTGTTAGC |
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2721 |
CAGGATGGTC |
TCAATCTCCT |
GACCTCGTGA |
TCCGCCCGCC |
TCGGCCTCCC |
AAAGTGCTGG |
TACTACAGGC |
GTGAGTCAAC |
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2801 |
GCGTGCGGCC |
TTTTTTTTTT |
TTTTTTTTTT |
TTTTTTTGAG |
ACGGAGTTTC |
ACTCTTGTTG |
CTCAGGCTGG |
AGTGCAGTGG |
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2881 |
AGTGGTCTTG |
GCTCACTGCA |
ATCTCCGCCC |
CCTGGGTTCA |
AGTGATTCTC |
GTGCCTCAGC |
CTCCCGAGTA |
GCTGGGATTA |
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2961 |
CAGGTGCCTG |
CCACAGTGCC |
CAGCTAATTT |
TTTTTTTTTT |
TTTTTAGTAG |
AGACGGGGTT |
TCACCATCTT |
GGCCAGGTTG |
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3041 |
GTCTTGAACT |
TCTGACCTCG |
TGATCCACCT |
GCCTCAGCCT |
CCCAAAGTGC |
TGGGATTAAA |
GGCGTGAGCC |
ACCGCGCCCG |
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3121 |
GCCAGCACGC |
TTCTTAATCA |
GCATGCAGGC |
TGTGACATGC |
GGAAACCAGG |
GGCACAGGCT |
CTGAAGTTTG |
TACTCTGGAG |
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3201 |
CTGGAGCAGT |
CAGGGTTAAA |
TGGGAGCGGC |
TGGGAAGGGT |
GTGTTTCCAC |
GAGGCCTTTC |
TGATGTCTCA |
GTGCCCAGTC |
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3281 |
TGGACCCGGG |
TAGAAGGTGT |
GGCCAGTGCC |
TTGAGTCAGT |
GGAGCAGTTG |
CCTGTGCCTG |
GTCTCTGTGA |
GATGGGTTGG |
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3361 |
TCAGGGGCTA |
GGCAGAGCCT |
GTGCCTGGTC |
TCTGTGAGAT |
GGGTTGGTCA |
GGGGCTAGGC |
AGAGCCTGTG |
CTGGGGGTAG |
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3441 |
CAGGTGCCCT |
CTAAAGGGGC |
CAGTGACAGT |
CTCTCTCCCA |
GCAGTGAGAA |
ACCCACGCTT |
AGGGGCCGGG |
CGCGGTGGCT |
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3521 |
CACGCCTGTA |
ATCCCAGCAC |
TTTGGGAGGC |
TGAGGTGGGT |
GGATCGCCTG |
AGGTCAGGAG |
TTCGAGACCA |
GCCTGGCCAA |
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3601 |
CATGGTGAAA |
CCCCATCTCT |
ACTAAAAATA |
CAAAAGTTAG |
CCGAGTGTGG |
TGGCGTGTGC |
CTGTAATCCC |
AGCTACTCGG |
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3681 |
GAGGCTGAGG |
CAGAACATTG |
CTGGAGCCTG |
GGAGGCGGAG |
CTTGCGGTGA |
CCCGAGATCG |
CACCATTGCG |
CTCCAGCCTG |
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3761 |
GGCGACACAG |
CGAGACTCTG |
TCTCAAAAAT |
AAATAAATAA |
ATAAATAAAT |
AAATAAATAA |
ATAAATAAAT |
CTGGCTTGAG |
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3841 |
TTTTGACAAA |
TGTATATGCA |
GGGTCAATGG |
GAAGACAGAC |
GCTGGAGGGT |
GGAAGCCTGA |
CTGTGAGAGT |
GAGCCCCCTG |
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3921 |
CTTTCCTGAA |
CAGTCAGTGG |
AGGAGGTCCT |
GGGAGCTCAG |
GTGAGCACCT |
GAACGGTAGG |
GCAGAGCCTG |
AGGGTCTTGG |
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4001 |
TGGAGACAGG |
CAAGAAGGTT |
GCAGGAACCT |
AGTCTGGCCC |
AGTGCCTGGG |
AGAACGGGAG |
GGAACACGGA |
GGCAGGGAGG |
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4081 |
CAGAGGGGTT |
GGCAGGACCT |
GGACTGGACT |
GTGCGTCGCA |
GCTACCCACA |
GCTTGACCCC |
ACTGCCTTGA |
AGTGAGTGAT |
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4161 |
GCACCCTCAC |
TAGTGTTCAG |
CGTCCAATTT |
CATCCTGGCC |
CTGAGTGTGT |
AACGGCTTTG |
CCCTTGCGGG |
GCCCCCTGGG |
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4241 |
ATGAGGGGTG |
AGCCCTGTCC |
CTTCCTGGTC |
ACTGTCTGCC |
ATCAGGAGCT |
GCCCCGCTTA |
CAGCTGTGAT |
TCAGGAGCCA |
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4321 |
CTGCATTTCC |
TCCAGCCCCC |
TGGGTGCTGC |
CAGGGGGTCC |
TCCTATTCTG |
GGAGCTGGTG |
TGTTCTGACT |
GGAGGCTGCC |
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4401 |
ATGTGCAGAG |
TGCTGTCAAG |
GAGAAGGGGT |
GTCCACTGCC |
CAGCCCTGAG |
GCCCAAGGCC |
TTGGCCAGCC |
TTGCTGCCAG |
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4481 |
CGCTGCAGGG |
AAAAAGCCTC |
CTTTGTGTGT |
GGGAAGTTTA |
ATAAACTCCG |
CTCAGATTGT |
GTCTCGCAGC |
GAGTGTCTGG |
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4561 |
AACCTTCCAG |
ACAAGCCTCA |
GGCGTCCGGT |
CCTCCAGTTG |
GTGTGGAAAG |
CGTGGGCGAT |
CACCAAGGGG |
GGTGGGTTGG |
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4641 |
GGCAGATGGA |
GCCGGCGTGA |
GTCCCGTCTC |
TTCCCTTCCT |
TCCCAGAAAG |
GCAGCCCTGG |
AGTCCATGCC |
TTGTCCCGCT |
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4721 |
CTCACCGGCA |
AAAAGTATAA |
TCTTATTAGA |
AATAGGAAAG |
TTCCAAAAAG |
CATCAATGAG |
TTAAAAAGAG |
GGCTGGGCAT |
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4801 |
GTTCGGTCAT |
GCCTGTAATC |
CCAGCACTTT |
GGGAGGCCAA |
GGCGGGTGGA |
TCACCCGAGG |
TTGGGAGTTA |
GCCTGACCAA |
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4881 |
CATGGTGAAA |
CCCTGTCTCT |
ACTAAAAATA |
CAAAATTAGC |
TGAGTGTGGT |
GGCGCACGCC |
TGTAATCCCA |
GCTACTCTGG |
|
4961 |
AGGCTGAGGC |
AGGAGAATCA |
CTTGAACCCG |
GGAAGCAGAG |
GTTGCGGTGA |
GCCAAGACCA |
TGCCATTGCA |
CTCCAGCCTG |
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5041 |
GGTAACAAGA |
GTGAAACTCC |
GTCTCGAAAA |
AAAAAAGGGC |
TGGGGCCGGG |
CGTGGTGGCT |
CACGCCTGTA |
ATCCCAGCAC |
|
5121 |
TTTGGGAGGC |
CGAGGCGGTT |
TGATCACAAG |
GTCAGAAGTT |
TGAGACCAGC |
GTGGCCAACA |
TGGTGAAACC |
CTCTCTCTAC |
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5201 |
TAAAAATAGA |
AAAACTAGCC |
AGGTGTGGTG |
GCACATGCCA |
ATAATCCCAG |
CTACTTCATC |
TGAGGTCAGG |
AGTTCAAGAC |
|
5281 |
CAGCCTGGCC |
AATATGGCGA |
AACTCCGTCT |
CTACTACAAA |
TACAAAAATT |
AGCCAGGCGT |
GGTGGCGCGC |
GCCTGTAGTC |
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5361 |
CAGCTACTGG |
GGAAGCTGAA |
GCAAGGAGAA |
TCGCTTGAAC |
CTGGGAGGCG |
GAGGTTGCGG |
TGAGCCGAGA |
TCGCATCATT |
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5441 |
GCATTCCAGG |
CTGGGCAAGC |
CTAGGAGAGA |
AGAGCGAAAT |
TGTGTCTCAA |
AAAAACAATT |
AATTAAAATA |
AAATCAGTGC |
|
5521 |
CATAGGCTGT |
TTCTGGTAGG |
CAGTGGGTTC |
CTAGGGTGGA |
GCAGGGAAGG |
GCTGGAAAGG |
GTCGCCTGTG |
CCCAGCCCGA |
|
5601 |
CTCCCCGTGC |
TTCTCGGGGG |
ACAGCACGGC |
TAGCTGCTGC |
TGCGGAGCCC |
ACAGTGGGGT |
TCTGGGGGGG |
GGGGTGCAGG |
|
5681 |
CAGAAGGCCG |
CCATGCCTCC |
CTCCCCCTTT |
CCACCCCAGT |
GAGAGTGGGC |
TCGAAGGCAG |
GGAGTCTGCC |
CGCCTTGTGG |
|
5761 |
AGCCTCCGCA |
GAGGCACCCA |
GGGCTGCCGT |
GAGCGCACAG |
CCTGGCGGTG |
TCCCACGGCC |
CTGCCCTTTC |
CTGTCACTTC |
|
5841 |
CACCTGTTGC |
AAAACACTGT |
GCTTTCGTAT |
CTTTTCTTTC |
TACCTGTTTG |
GAAATGTGAA |
AATCACTGCT |
GCCGTAGGAA |
|
5921 |
ACGGGCCCAG |
ATCCGGGCTG |
TGGCTCTCCC |
ATCCGCACCG |
CCCCCGCGGT |
GTCCAGCCAG |
GAGGTGGGAG |
GTGGGCGGCA |
|
6001 |
CTCAGTGTGC |
CTGGTTGCGG |
CGATGATTGG |
CAGATGCTTG |
GACCTATGGT |
AAAGAGGATT |
TTCGCGAGCT |
GGGAGTCAGT |
|
6081 |
CCTGGACTTT |
GTAGGTCTTT |
ACATCCCAGG |
CGGCCTTTAT |
GGGGTTCCAG |
CATCTGCTGA |
GGCCCCTGCG |
CCAGCCATGT |
|
6161 |
GAGGCCTGGG |
TGTCCTCGAG |
GCCTCTGTTT |
GTGCCCCTCT |
CTGGGCAGCG |
GGAGGGAGAG |
CTCTGAGACC |
CAGAGGGAGC |
|
6241 |
TCAGGGGCTG |
GGCAGCCGCA |
GAACAGCGGG |
GGTAATGGGT |
CCACTGGGGG |
TTCTGGGCTG |
TGCACACAGT |
GGGCTTCCGG |
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6321 |
TGCCCAGCCA |
GCTGGGGCAG |
GCCTGGAATG |
TTGGTTCCTC |
TCTCAGGATC |
TGGGGCGCTG |
CTGTAGCTGT |
CGGGGAATCA |
|
6401 |
GTGAGGCGGC |
TGGACGGCCC |
GTATATCCCA |
CAAACGCCAC |
CGTATTGCTC |
AAACTGGACT |
CAATTTTCTT |
AACACCTTTT |
|
6481 |
TTTTTTTTTT |
TTTTTTTTTT |
TTTGGAGACA |
GGGTCTCACT |
GTATCGCCGA |
GGCTGGAGTG |
CAGTGGCGCA |
ATCATAGCTC |
|
6561 |
TGGGCTCAGG |
TGACCCTCCT |
GCCCCCAAGG |
TAGCTGGGAC |
TGCAGATGTG |
CACCACCACA |
CCCGACTAGT |
TTTTTGTAGA |
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6641 |
GATGGGGTTT |
CGCCATGTTG |
TCCAGGCTGG |
TCTCAAACTC |
CTAGACTCAA |
GCTATCCGCC |
TGCCTGGGCC |
TCCCAGAGTG |
|
6721 |
CTGGGATTAC |
AGGTATGAGC |
CACTGCTTCG |
CCACGTTCAC |
CTTTATTTAC |
TTATTTATTT |
ATTTTTGAGA |
CGGAGTCTCG |
|
6801 |
CTCTGTCCCC |
CAGGCTGGAG |
TGCTGTGGCA |
CGATCTTGGC |
TCACTGCAAG |
CTCCGCTTCA |
GCCTCCCAAG |
TAAGCTGGAA |
|
6881 |
CTACAGGTGC |
CTGCCACCAA |
GCCTGGCTAA |
TTTTGTTTTT |
GTATTTTTAG |
TAGAGACGGG |
GTTTCACCGT |
GTTAGCCAGT |
|
6961 |
ATGGTCTCGA |
TCTCCTGACC |
TTGTGATCCG |
CCCGCCTCGG |
CCTCCCAAAG |
TCCTGGGATT |
ACAGGCTTGA |
GTCACTGTGC |
|
7041 |
CCGGCCCACC |
TTTTTATTTT |
TTATTTTATA |
GAGACAAGGG |
CTTGCTGTGT |
TGCCCAGGCT |
GGTCTTGAAC |
CCCTGACCTT |
|
7121 |
AAGTAATCCT |
CTCTGGCCTC |
CCAAAGTGCT |
GGGATTACAG |
GTGTAAGCCA |
TAGTACTGGG |
CCTAAAGTTC |
ACCTTTTTTT |
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7201 |
TTTTTTTTTT |
TTTTTTTGAG |
ATGGAGTCTC |
GCTCTGTCAC |
CCAGGCTGGA |
GTGCAGTGGC |
GTGATCTTGG |
CTCACTGCAA |
|
7281 |
GCTCTGCCTC |
CCGGGTTCAC |
ACCATTCTCC |
TGCCTCAGCC |
TCCCGAATAG |
CTGGGACTAC |
AGGCGCCTGC |
CACCATGCCC |
|
7361 |
GGCTAATTTT |
TTTGTATTTT |
TAGTAGAGAT |
GGGGTTTCAC |
TGTGTTAGCC |
AGGATGGTCT |
CGATCTCCTG |
ACCTCGTGAT |
|
7441 |
CTGCCTGCCT |
CGGCCTCCCA |
AAGTGCTGGG |
GTTACAGGTG |
TGAGCCACCG |
CACCCGGCAA |
AGTTCACCTT |
TTTAAAGTGT |
|
7521 |
GTAATTCAGT |
GGCATATAGT |
ACATTGACAG |
AGTTGCACAA |
CTATCACCTC |
TATCAGCTTC |
CAGAACATTC |
TTGTTACCCC |
|
7601 |
AGAAGGAAAC |
CCCGTCTCTG |
TCAGCCATCA |
CTCCCCATTC |
CCTCCCCAGT |
CCCGGCACCC |
ACGCATTCCC |
TTCCTGCCTC |
|
7681 |
TGGATTGGCC |
TGTCCTGAAC |
ATTTCACACG |
AGTGGTGTCA |
CACACCGCGT |
GGCCTTTTGC |
GTCCGGCTTG |
TCTCACGGAG |
|
7761 |
TGTGCTGTCC |
TCAAGGGGCA |
TCCGCGCCGT |
GGCCTGGGTC |
CGAACCTCTC |
TGCTGTTCAC |
GGCTGCGTCA |
CTTTCCAGTG |
|
7841 |
TGTGGAGGGC |
CACGCTGCGT |
TTGACTGCTC |
ATCTGTGGCT |
GGACACTTGG |
GCTGCTCCCG |
CCTCTGCCTG |
TGAATTGTGG |
|
7921 |
CTGCTTTGGT |
GCACGTGTGC |
TCAGCCGGCG |
TCCCTCTAGA |
ATCCTTGAGG |
GCCTTGTTTC |
AGCCACATCA |
GGAGGGATTC |
|
8001 |
AGGGACCAGG |
GCACGCGGGT |
CTGGAGCTGG |
GTGTTCCTGG |
GTCTCCATGT |
GCCTCCCAGT |
CCTGCTCTGA |
GCCGTGGGAG |
|
8081 |
GCCGGGGCGA |
GGGCCAGGCC |
CATCTCTTCC |
CTGTATGATC |
TGTTTCTAGG |
CAGACGGAGG |
CTCCTAGCCC |
CACCTCTCTG |
|
8161 |
TGAGCTTGAG |
TGGCGTTTAT |
GACTCTCCTT |
CCTATTTCCT |
GTCCTGCTAA |
TCAACAAGTC |
AGCTAAACAG |
TCCATGCTGC |
|
8241 |
CTGGGCAAGC |
CCAGTAGGCC |
CCTAACGTGG |
CACCTCGGAG |
CGGCTGGCGA |
TGCCCCAAGA |
GCCGGGCTTC |
CCCCTCCTGG |
|
8321 |
AGGCTCTTCC |
TGTTCCTCGC |
CAAGCTCTTA |
GGTTTCGCTG |
GGCCTCCTCT |
TCTGCTCTTT |
TTCTGGCTGG |
AGACGTCAGA |
|
8401 |
GGAAGCCTGG |
CGATCTAGAG |
AAGCTGATGT |
GCACCCATCA |
TCCCGGAGGT |
GACTGCCACC |
AGGCGGGGGT |
GGCTCCACCC |
|
8481 |
CCACTCCTCC |
CCTGGCATAA |
ATCGGGGGAC |
GCACGTGCCT |
GCGCAGAATG |
CCTTGGTCCC |
TTTTAATTAA |
ACAGACAACC |
|
8561 |
CAGTGTCCCT |
TGGTCTATGC |
TGACCTGCTC |
AGGAGTGCCT |
GGGCTCTTCC |
ACGTTTCAGC |
TGCTGTGTGT |
CCTGCTGCTG |
|
8641 |
TGAAGTGTCC |
CCGTTGAGGT |
GGAGGCAGGG |
CAGGGCGCCT |
TCGGTGAGGG |
CGAGTCCTCC |
TGTGCCCGTT |
TCCCCATCTG |
|
8721 |
TAGAATGATG |
GCTCATGGAG |
GAGACATGGT |
GTCGGCAGGT |
GGTGGCCGGC |
GCAGGGAGGT |
TTCCAGGAGG |
GAGTCCTCCA |
|
8801 |
CCCTCATTTG |
CTTTTAGGGC |
CGTGCAGCCT |
CCCGAGCGGC |
CCCCACGAGG |
CTCTGAGGCT |
GCATGCAGGT |
TGAGCTCCTG |
|
8881 |
GCCTCACTGC |
CCCTCCTCAG |
GGTTAGGACT |
GTGCTGGAGC |
CTGGGTGGGT |
GTGGGGTGGT |
CCCTGCACAG |
GCAGCAGGAG |
|
8961 |
GTGGGCCAGA |
GCGGTGCTGG |
ACCTGAAGGC |
CCGTGGCTCC |
CTCAGCTCCA |
CTGAGGAGGC |
TGGAATAGTG |
TCCTGGGCCA |
|
9041 |
CCTTCCCTGC |
CGGTAGCCGG |
CTCCTGCTGA |
GGGAGGGGGT |
GCTTTCGCCT |
CCTGGTGGAG |
CATCAGGCTC |
TTGGGGCCTG |
|
9121 |
TGCGTCCGAG |
CATCTGGCCT |
CTGCTGTCTG |
AAAACAGCAC |
CTTCCCCGCC |
CCCCGGCCAC |
CGCATCTCCT |
CTGAATAGAA |
|
9201 |
GGCAAGTCTT |
GCCTCCCAGG |
AATGGCCTGT |
GACCTTCATC |
AGCGGGGGAG |
GTTAGGGGCA |
CACAGAGCCC |
TGGGGAACAA |
|
9281 |
GGGGATCTGG |
GGCTGAGCCG |
GGCCTCTCGG |
GCCCACCCCG |
AGCTCTCCTG |
AGCAGCCTGG |
CAGGCAGGAA |
GGCGCTGGGC |
|
9361 |
CCCGGGGCCT |
TTGCCGAGCC |
CAGCCTCACC |
CTCAGCGTCC |
CCCTCAATGC |
CCTGGGTGCC |
TGCCAGGCTG |
TGGACACAGG |
|
9441 |
CCCTGGCCAG |
TTCTATAAAT |
AACCTTGCCG |
GGCCCTGCTG |
GGAATTGGTG |
CCACCACCAC |
ATAGCCCAGA |
GAGAACGGAA |
|
9521 |
ACACAGGGCT |
TCTCAGCGAG |
CAGACCAGGC |
CTGCGGTGAC |
CAGTGGAAGT |
GGGGGACGCT |
TTCAGGGCTG |
GGCAGCCCGA |
|
9601 |
CAGGGCACCG |
GGCACAGCCA |
GGGGCCGGAA |
CCAGTTGCTC |
ACTGGCTCCG |
CTTCTGGGGG |
ACTGTGTCCC |
TCTGTGCCCC |
|
9681 |
GTCCCCATCA |
CACCTTGCTT |
TCCCTTCATC |
CTGCTCTCCT |
AGCCCCTCCC |
CAGACTGGCG |
GCCCCTTGTC |
CAGGCCCAGC |
|
9761 |
CCCAGCACAG |
CCTGCAGCCC |
TGGCAGAGCT |
CAGGCCTTGG |
CCTTCTGAGG |
TTGCCCTGAG |
GGCAGTGAGC |
AATGAGCCCT |
|
9841 |
GGGACTGGTG |
CACTGGGAGG |
GAAAGGTGAG |
CCAAGGCTTC |
CTGCAAGAGG |
CAGCCCTGAG |
CTGGGGGTGG |
GGAAGGCTGG |
|
9921 |
GTCGTGGGAT |
ACCCCTGACA |
CCCCAAGTTT |
TTTTTTTGAG |
ATGGAGTCTT |
GCTCTGTCAC |
CCAGGCTGGA |
GTGCAGTGGT |
|
10001 |
GAGATCTCGA |
CTCTCTGCAA |
CCTCCGCCTC |
CCAGGTTCAA |
GCGATTCTCC |
TGCCTCAGCC |
TCCTGAGTAG |
CTGGGATTAC |
|
10081 |
AGGCGCCCAT |
CACCACGCCC |
GGCTAATTTT |
TGTATTTTTA |
GTAGAGACAA |
GGTTTCACCA |
TGTTGGCCAG |
GCTGGTTTCG |
|
10161 |
AACTCCTGAC |
CTCAGGTGAT |
CCACCTCGGC |
CTCCCATAGT |
GTCGGGATTA |
CAGGCGTGAG |
TCACCGCGCC |
TGGCCCCCCA |
|
10241 |
GCTGTTTTTT |
ATGCTCCATG |
CTTGGGCTTC |
CTGTTAAGAA |
TTAAAAAAGA |
AAAAAAAAAC |
TATGGAGATG |
GAATTTACAT |
|
10321 |
ACTGTACAAC |
TCATTCGTTC |
ACAGTGTACA |
ATTCAGTGGC |
ATTAAGTACA |
TTCACACGGC |
TGTGCAACCA |
CTACTTCTAA |
|
10401 |
TTCCAGAACG |
TTCGGTCACC |
CCAAAAGCAA |
GCCCCATTCC |
CATTGTGTCA |
CTCTCCATCC |
CCTCCACCAG |
CTCCTGGCCA |
|
10481 |
CTCTGAATCC |
ACTTCCTGGC |
TCTGGATTGG |
CTTGTCCTGG |
ATATTGCATA |
GAAATGGGAT |
CCTGTCGGCC |
GGGCGCGGTG |
|
10561 |
ACTCACGAGA |
GCAAGAGATC |
CAGACCATCC |
TGGCCAACAT |
GGTGAAACCC |
CATCTCTACT |
AAAAATACAA |
AAATTAGCTG |
|
10641 |
GGCGTGGTTG |
CGGGCACCTG |
TAGTCCCAGC |
GACTCAGGGG |
CTGAGTCAGG |
AGAAATCGCT |
TGAACCCGGG |
AGGCAGAGGT |
|
10721 |
TGCAGTGAGC |
TGAGATCATG |
CCATTGCACT |
CTGGCCTGGC |
GACAGAGTGA |
GACTCCGTCT |
CCAAAAAAAA |
AAAAACAAGA |
|
10801 |
AATGGGATCC |
TGTCATCCCA |
GCGTTTTCCG |
AGGCCGAGGT |
GGGCAGATGA |
CTTGAGCCTA |
GTAGTTCAAA |
CGAGACCAGC |
|
10881 |
CTGGGCAGCA |
CGGTGAAACT |
GTCTCTACTA |
AAATACAAAA |
ATTAGCTGGG |
CATGGTAGCA |
CACGTCTGTA |
GTCCCAGCTA |
|
10961 |
CTTGCGGGGC |
TGAGATGGGA |
GGATCGCTTG |
AGCCTGGGAG |
GTGCACTCCA |
GCCTGGGCGA |
CAGGGAAACC |
CTGTCTCAAA |
|
11041 |
AAAAAAAAAA |
AAAGTGCATC |
ACACACTGTG |
TGTCCTTTAG |
TGTCTCACTG |
TGACATCCTC |
AAGGTGCAGC |
TAGGCTGTGG |
|
11121 |
CTCGAGTCAG |
AGCCTCACTG |
GTTTTTGTGG |
CTGAGTCTTG |
TTGAGTGCGT |
GGATGGGCTG |
TGCTGATCCT |
CGTCTGTGGA |
|
11201 |
AGGGCCCCTG |
GGTGGTTCCA |
CATCTCGGCT |
GCTGTGCGTC |
CTGCTGCTGT |
GAGCATCTCG |
TGCTCCGTTT |
CTGCGTGGCG |
|
11281 |
TGTACTGTTC |
CTCAGGGTGT |
GTACCTGGGA |
GTGGAGCTGC |
TGGCTCACAG |
GGTAACAGAC |
CTTTGGAGAA |
GCTGCAGACG |
|
11361 |
CTTCCACGCC |
CACCCACTGG |
GTGTGAGGAC |
CTTGCTCCTC |
GTCATTTTTG |
TTTTTGTTTA |
ATTTTTTCTT |
TTATGAGACA |
|
11441 |
GGGTCTTATT |
CTGTTGTCCA |
GGCTGGAGTG |
CAGTAGCACG |
ATCACAGGTA |
ACTACAGGCT |
CAAGTGATCC |
TCCCACCTGA |
|
11521 |
GCCTCCCGAG |
TAGCTAGGAC |
TTGAGGCACG |
TACCTCCACA |
CCTGGCTAAT |
TTTTGTATTT |
TTAGTAGAGA |
CAGGGTTTCG |
|
11601 |
CCGTGTTGCT |
CAGGCTGGTC |
TCGAACTCCT |
GAGCTCAGGT |
GATCCACCCG |
CCTCGGCCTC |
CTATAGTGCT |
GGGAGAAATG |
|
11681 |
AAGTGTCTGC |
GACAGGGCGG |
CAGCTGCAGA |
GGGGGCTGTG |
CTCTCTGGCC |
TGTTGTGCCC |
CACCCTTGTG |
ACAGGCAGGT |
|
11761 |
GGGCGTGGCC |
AACTGGGCGG |
CAGCTGCAGA |
GGGGGCAGTG |
ACAGGCGGGT |
GGGTGTGGCA |
GGACCCCACA |
ATGTCTCTTT |
|
11841 |
CTGTGGCGTC |
TCCTTCTTCG |
CCTGCCCCTT |
CCTATGGGCC |
ATCCTTCCAG |
CTCACCTGCG |
GCCCACCCTC |
CAAGGAGTGG |
|
11921 |
GACCCTCGGA |
GTTGGGAGCC |
CTTGGCTGCG |
TGGGACTGTA |
CTGTGTGACG |
GAGCCATCAC |
CAGGGCTCCA |
ACTCACCCTG |
|
12001 |
GCTCCTGCCA |
CAGTCTGGGC |
TCCATCTGTG |
CTACCATTGC |
AGTAGTCTGG |
TTTCTAGGAA |
GCAAAACTGT |
TACTGAGTTA |
|
12081 |
CAAAGCTCAA |
TTAAGAGTGT |
CCTTTGGGAG |
GCCGAGGCGG |
GCGGATCACA |
AGGTCAGGAG |
ATCGAGACCA |
TCCTGGCCAA |
|
12161 |
CATGGTGAAA |
CCCTGTCTGT |
ACTAAAATAC |
AAAAAAATTA |
GCCGGCTGTG |
GTGACACGTG |
CCTGTAGTCC |
CAGCTACTCG |
|
12241 |
GGAGGCTGAG |
GCAGGGAAAT |
CACTTGAACC |
TGGGAGGCAG |
AGGTTGCAGT |
GAGCTGAGAT |
CGGGCCACCG |
TGCTCCAGCC |
|
12321 |
TAGGGACAGA |
GCAAGACTCT |
GTCTCAGAAA |
AAAAAAAAAG |
TGTCCTAACT |
GTGTCCTCCA |
AAGCCCTCGC |
CGGCCGATGA |
|
12401 |
CAGACTAGAG |
GGCGCTGTGC |
TCCCACCCCC |
TACCGCCCTG |
AGCCTGGACG |
CGTGGCCCCT |
GCAGGGCCCT |
TTCCCACAGC |
|
12481 |
ACTGTGAACT |
CACAGCTTCT |
CTCTAGGGAA |
GGGAGGAGGT |
ACGCCACTTC |
CACAGGGAGA |
TGGGGAGGCC |
GACTCCAGGG |
|
12561 |
ATCCAGGCCA |
TCATCCTGAC |
GTTGGGTCGG |
CTGATACACC |
CCTGTCCTCT |
CTGTCCCAGG |
GAAATTCAAC |
TACTGAGGAG |
|
12641 |
GTTACGGCAC |
AAAAATGTCA |
TCCAGCTGGT |
GGATGTGTTA |
TACAACGAAG |
AGAAGCAGAA |
AATATATCCT |
TTCCGGTGTT |
|
12721 |
GGGACCGCGG |
GGCCTCCGTG |
GGAGGGGCTG |
GGGCCCTGGG |
TCCGCCTGCC |
TCGAGGCCTG |
CTCCTCTTCC |
CGTCTCCTTG |
|
12801 |
AAGGAGACTG |
GCACACGAGG |
GCCGTGGCCT |
TCCCTGGTTC |
CCCGGAAGTC |
AGCCATTGTG |
GCAATGGCTG |
CGCAGCTTGC |
|
12881 |
TGAAAGGGGC |
CCTGAGCCCT |
GGCCCCTGTG |
TCTTGGGCCC |
GTGGGGTGTC |
AAGTCCCTTT |
TTTCTCAGAG |
TCTCCTCCCA |
|
12961 |
GGCTAACCAG |
GGGTGTAGCC |
ACGGTCTGCC |
TGAGACAGGC |
CACGCGGGCT |
GACCGTTGTG |
GGCCATTTTG |
GTCGTGGCTG |
|
13041 |
GGCGTGTCCT |
CGTGTCATCT |
GTGGACACCC |
CCATGGGTCT |
TACGGGCACA |
GCCTCCCTAC |
GGGGACTTTG |
CTTCCTAAGG |
|
13121 |
CCCTGTGCCC |
AGAGCAAGAG |
CCAGAAGTGG |
TCCTGAGGCT |
GGGGCTGTGT |
TCCCTGAGCC |
ACGCGGTCAG |
GGGCCCTGGG |
|
13201 |
ACCGTCCTGC |
ATGGGCCCGA |
GCCTGCTTGG |
GGGGGCGTCC |
AGGAGGCACC |
ATCCCCCGCC |
CATGGGCAGG |
GTGGGGGACG |
|
13281 |
TGAGCCCCGC |
AGGAACGCTG |
CCCCAAGAGT |
CAGCCCTGTC |
CTCCCCTTCC |
CCGTAGGCTC |
CTTCCTCCTG |
GGACGCTGGG |
|
13361 |
GCCCCTGGGC |
CTTTTCAGAG |
GGGTGGCTGA |
GGGCAGGGTG |
GGCCCTGGTC |
CCGAGGAGGG |
GCAAGGTGGG |
TGCAGAGGGT |
|
13441 |
CCCTCCAGAG |
CCCCTTTTCT |
GGCCCCCGTG |
CTCCCTGGGC |
CTGTGAGTGG |
GGCCGCCCCC |
TGAGCTGTGT |
GTCCTTAGCG |
|
13521 |
CCCCACGTAT |
ATGGTGATGG |
AGTACTGCGT |
GTGTGGCATG |
CAGGAAATGC |
TGGACAGCGT |
GCCGGAGAAG |
CGTTTCCCAG |
|
13601 |
TGTGCCAGGC |
CCACGGGTGC |
GTGCGCGGGG |
CAGGGGCCAG |
GGTGGGGCGG |
GGGCCGGGGG |
CCAGGCAGGG |
CAGGCTCCTT |
|
13681 |
TCCGTGAGGC |
CACACTGCTT |
GTCCTGATAT |
TCATTGACAT |
GAAGGCCCAA |
GTTTTTTTGT |
TTTTTTGTTT |
TTTTGTGTTT |
|
13761 |
TTTTTCGAGA |
TGGAGTCTCA |
CTCTGTCGCC |
CAGGCTGGAG |
TGCAATGGTG |
CGATCTCGGC |
TCACTGCAAG |
CTCCGCCTCC |
|
13841 |
GAGGTTCACG |
CCATTCTTCT |
GCCTCAGCTT |
CCCGAGTAGC |
TGGGATTACA |
GGCGCCCGCC |
ACCACGCCCG |
GCTAATTTTT |
|
13921 |
TGTATTTTTA |
GTAGAGACGG |
GGTTTCACCG |
TGTTAGCCAG |
GATGGTCTCA |
AACTCCTGAC |
CTCGTGATCC |
GCCTGCCTCA |
|
14001 |
GCCTCCCAAA |
GTGCTGGGAT |
TACAGGCATG |
AGCTACCACG |
CCCGGCCTTG |
TAAAGGCCCA |
AGTTTTTAAA |
AACAGTTTTG |
|
14081 |
GGGTCCCCCA |
TGTGTGGCAT |
CCACAGGCAG |
GGCTGCTGCC |
AACCTCCCGC |
CTCCATCTTT |
GCTGGGCCTG |
CTGCCTGAGG |
|
14161 |
CCAGTGGCCT |
GCTTCCAGCC |
CATCGCTGGC |
AGCCGCCTGC |
CCTGACCAGA |
TCTCCTGGAT |
GCAGGTCTGT |
GGCCTCAGAG |
|
14241 |
TCAGGGCCCC |
TTGCTGCTGC |
AGGACCACAG |
GGGCAGGGAG |
GGGCCTGCTG |
TTCCAGCAAG |
ACTTTGGGGT |
GCAGCCGGCC |
|
14321 |
TGTGGCCCAC |
AGGAAAATGA |
GACCTGTGGA |
CATCCGGGGC |
CCTGCCAGAC |
GTGGCTCGGC |
CGGACGAGGG |
TGGCCACTGC |
|
14401 |
AGGCGCAGGT |
GTGGCTCCCT |
GCTGGACCTA |
GCCTTTCCTC |
TGTCCTGTGT |
GCCTGGACTT |
CTGTGACTTC |
CCAGCTGGGC |
|
14481 |
CTGTGGTGTT |
TGGGAGGCTC |
CCAGGCAGCT |
GCAAAGGGGA |
CCCCTGTGAG |
GGGCAGGGAG |
GCCTCGGCCC |
CAGGACGGGT |
|
14561 |
GTGTGCTGCC |
CGCAGGTACT |
TCTGTCAGCT |
GATTGACGGC |
CTGGAGTACC |
TGCATAGCCA |
GGGCATTGTG |
CACAAGGACA |
|
14641 |
TCAAGCCGGG |
GAACCTGCTG |
CTCACCACCG |
GTGGCACCCT |
CAAAATCTCC |
GACCTGGGCG |
TGGCCGAGGT |
AGGCACGTGC |
|
14721 |
TAGGGGGGGC |
CCTGGGGCGC |
CCCCTCCCGG |
GCACTCCCTG |
AGGGCTGCAC |
GGCACCGCCA |
CAGGCACTGC |
ACCCGTTCGC |
|
14801 |
GGCGGACGAC |
ACCTGCCGGA |
CCAGCCAGGG |
CTCCCCGGCT |
TTCCAGCCGC |
CCGAGATTGC |
CAACGGCCTG |
GACACCTTCT |
|
14881 |
CCGGCTTCAA |
GGTGGACATC |
TGGTCGGCTG |
GGGTCACCCT |
GTAAGTGCCC |
CGCCCCCCCG |
GGCACTCACC |
ACACGCACAC |
|
14961 |
TCCGAGGGGC |
CTCTGCGTCT |
TGGGCAGCTG |
CCGGCCTGTG |
GGCGCAGGGC |
GTGGCCACCG |
GCCCAGACCC |
TCTCTGGCCA |
|
15041 |
CAGCCGCTAG |
GGGGTGCTTA |
CTTTATGGAA |
ATGTAACTCA |
TACGGCAGAT |
GGTGGTTCAC |
CCGTGTGAAG |
TGCAGCCTGG |
|
15121 |
CCCGTCAGGG |
ATCTTCACAG |
AGTGGCACGG |
CCGACCCTCC |
TCCCAGAGCC |
CCACAGGGAA |
GCTGGGCGGG |
TGACAGCAGC |
|
15201 |
TCCAGGCCCC |
TTCCCCGGGT |
GGGTCCAGAG |
GACACTCCCC |
TCCTACCCCG |
TAGCCTCCAC |
TAGTGGAAGG |
TGGTGAAGAC |
|
15281 |
AGAGGTGTCC |
TTGAGTCCAC |
AGGGCCTCTG |
GTCCAGCAGC |
CACGGGACGC |
CTCTGTCCCT |
GGGGTAGAGC |
TGGGGCTCCT |
|
15361 |
AGGGCGTCAA |
CCACCTTGAC |
TGACCACGCC |
TTTCTTCCCT |
CCCCTCGAAA |
TGAAGCTACA |
ACATCACCAC |
GGGTCTGTAC |
|
15441 |
CCCTTCGAAG |
GGGACAACAT |
CTACAAGTTG |
TTTGAGAACA |
TCGGGAAGGG |
GAGCTACGCC |
ATCCCGGGCG |
ACTGTGGCCC |
|
15521 |
CCCGCTCTCT |
GACCTGCTGA |
AAGGTGGGAG |
CCTCATCCCT |
CTGCCCGCAG |
CCCCAGGGAG |
GCGGGGCTTT |
TGTGCAGAAA |
|
15601 |
TGTAGGGTTG |
GGGGTGTCAG |
GTGGGGGGCT |
ATTGGCCCCG |
AGACCCCAGC |
AGGCATTGAG |
AGGACTGAGT |
GGAGAGGCCG |
|
15681 |
ACCTCCCCGC |
AGGGCCTGGT |
TTGCCAGGTC |
CCTCAGCTCC |
ACCCTGCTTC |
TGGGCCCTGT |
TCACCCTCCG |
AACTCCCACC |
|
15761 |
CCAGAGGGCA |
GTGCTGCCCT |
GCGCCTCCCC |
CAGCCCCACC |
CTCGGGGGCT |
CCCTGGCTTG |
CAGGGTCTGT |
CAGGGTTGTC |
|
15841 |
CTGCTGCACT |
TCCTACGCAT |
GGCAGCAGGT |
GGCACTGGCC |
GTCCGTCCAT |
CTGCCCAGTG |
GCCTTGGGAG |
AACGGAACCG |
|
15921 |
CCCTGGCCGT |
CCAGCCCAGC |
CCTGTCTCCC |
TGCCAGCCGC |
GCACAGGCTG |
TCCCCGGCAT |
GTCCCAGGAG |
TGGAGTGGCC |
|
16001 |
TCTGTCAGGG |
AGACCGCCTG |
TGCGCGGGGT |
CCCCCTTAGG |
AGCGTCCAGG |
TATCACCCAG |
GGCCTGACAA |
CAGAGGCTGG |
|
16081 |
GCAGGCGGGG |
ACGGTTGGTG |
GGGTCTCAGG |
CCTGTGCCCA |
GCTGACAGGC |
TCCTCGCCGG |
CTTCTCCTCA |
GGGATGCTTG |
|
16161 |
AGTACGAACC |
GGCCAAGAGG |
TTCTCCATCC |
GGCAGATCCG |
GCAGCACAGG |
TGAGCGGCCC |
CTGGGGGCAG |
TGGGGCCGAG |
|
16241 |
GCTGCAGGGA |
GGCCGGCCAT |
GTGGGCAGCT |
GGTTGAGCGG |
GCGCTAGAGC |
AGGGCGTGGT |
GGGGGTGCCA |
GGCTGGGCTG |
|
16321 |
GGGCCAGACC |
CCGTGCAGCG |
CCCGCAGTTC |
TCGGGGCCCG |
AGTGGGGTCT |
CTGGGCAGTG |
TCCTGTTACC |
GGCCAGACCC |
|
16401 |
AGGCGCCTTG |
TCCGAACTGG |
GGTCTGAGTG |
AGGACATGCG |
TCCGTCCCTG |
CCCTAGGCAT |
GGAGATGCGC |
CAGGAAGGGC |
|
16481 |
ACAGCTGGTC |
CCAAACACTG |
GCGAGAGCCT |
CTCTTTTTCC |
CCTCCTCCTG |
GGGCTCCCAG |
CAGCAGGGTG |
TGGCTGGGAT |
|
16561 |
CCAGCCCAGG |
GCCCCCAGCT |
CCATGACAGG |
GAAGACAGAG |
CAGCGGACGG |
GGTCAGCAGG |
CCCCACAGTG |
CCGCCTCCCT |
|
16641 |
CACTTCGTGG |
GCTCTGCTCC |
TCTGCACCAG |
CCCCTGGAGG |
CCCTTGAGCC |
GTCTGCTGGA |
GCCCCTCCGA |
GCCCCGAGGC |
|
16721 |
CACCCACTGA |
GACCGGCTCT |
GGGAGTGGGA |
GTGTCCGGAC |
CCCTGAGGCG |
CTGGTGCTGA |
TTGTGCCTTG |
GGGGTCTCTG |
|
16801 |
CACAGCTCGG |
GTCATCTGGG |
CGCCTGGCGG |
GGACTGGGGC |
TGCCCCCCGA |
TAGCCTCCTG |
GGCTGGGATG |
TGCTCAGGGC |
|
16881 |
CCCCCAGACC |
CCCTTCTGGC |
CTTTGCTGGC |
TTTGCAGCCA |
GCATCCATCT |
GGTGGGTGCT |
GGCTTCTGAG |
TGCCACCTGG |
|
16961 |
GACACAGGCC |
TCAGGGTGGA |
GGGGACATCT |
GTCAGGCTTG |
GAGTCAGGTC |
AGCCTGCCTG |
CTCCTAGAGG |
ACATGGCTGA |
|
17041 |
GCTTCTGTGG |
TCACAGCCAC |
CCCTTGCACG |
GCCTGGTCCC |
AGCTCCTGAG |
TGTGTGGCAG |
GTACCCTGGG |
CCCAGAGGAG |
|
17121 |
CTGGGTCGGA |
AAACTGGACC |
GCCCTGGTGC |
CAGCCTGACA |
GGCGCCACTG |
CTTCTGGGCG |
TTTGCAGCTG |
GTTCCGGAAG |
|
17201 |
AAACATCCTC |
CGGCTGAAGC |
ACCAGTGCCC |
ATCCCACCGA |
GCCCAGACAC |
CAAGGACCGG |
TGGCGCAGCA |
TGACTGTGGT |
|
17281 |
GCCGTACTTG |
GAGGACCTGC |
ACGGCGCGGA |
CGAGGACGAG |
GACCTCTTCG |
ACATCGAGGA |
TGACATCATC |
TACACTCAGG |
|
17361 |
ACTTCACGGT |
GCCCGGTGAG |
TCTGGCGGGG |
GCCCCTGCCC |
GGCTCTGCTG |
ACTCGGCCAG |
GATGTCCCAC |
GGGAGCAGGG |
|
17441 |
TGCCTGCCTG |
TCTGCAACAA |
GGACAGCTTC |
TGCCCTCTGG |
TGGCCAATCC |
CACGTCCCCA |
AAGCCTCCAG |
CCCACCTGCA |
|
17521 |
GGCTGCCTCC |
GCCCTGCGGG |
CCGCTGGGAC |
ATGGCTGAAA |
GGTGTGGGGT |
CAGCGGGGGC |
ACCAGCCCAG |
GCCTGTCTGG |
|
17601 |
CCAGGAGGGT |
TCCTCAGGCG |
TCTCTCCGGG |
TGCTGCCCAG |
CCAGGCACCA |
CCCACCGGCC |
TTGGCCTGAG |
TCCCAGCAGG |
|
17681 |
AGCAGGCGGG |
GGAGCCCCAG |
GGTCGGGGGA |
GGGTAGGTGA |
GAGTCAGGGT |
GCAGGGTGGC |
CCCTCAGACA |
GCTGGCATGA |
|
17761 |
GAGAGGGTCC |
AGTGGCCCTC |
CCTCCCGTCG |
TCCCTGAGGC |
CTGCCCGCTG |
GCCCTGATGC |
CGGCCGCCCT |
TCTTCCCTAG |
|
17841 |
GTGGCGAGGA |
GGCGTCTGAG |
GCAGGGCTTA |
GAGCGGAGCG |
CGGCTTGCAG |
AAGAGCGAGG |
GCTCAGACCT |
TTCAGGAGAG |
|
17921 |
GAAGCCTCTC |
GGCCGGCGCC |
GCAGTAGTGC |
CTGAGGAGGA |
GCTCAGGGCC |
TTAGCGTAGG |
GGCGGCCCAC |
ATTGGCAGCC |
|
18001 |
AGCCCCTCCC |
CGCCATGCTC |
CCGGCTTGGC |
TGTGTTCGGC |
CCAGGGCTGG |
GCCGTGTCAT |
AAAGAGTTTT |
GCAGTGTATC |
|
18081 |
TGCAGGGTGG |
ATGCTTGCTG |
CGCTCGGGCT |
GGAGCCTGAG |
GGGGCTTTCT |
GCTTTACTGT |
TTCAGCGGGA |
AGTGGTGGGC |
|
18161 |
AGGGGCCGGC |
CTGAGAAGGG |
GGGTACGCCA |
GGCAGGTTGG |
GATGTGAGGA |
CCCAGTGCAC |
AGGGTCCACC |
CCCGGGCCCG |
|
18241 |
AGGGTCCCAG |
AATAGTGGGG |
GCCCTGCAGA |
GAGCCCCCCA |
TTAGGTCCCT |
CAGCACTCCT |
GGGCCCCTCA |
TCAAACCCCT |
|
18321 |
AGGCTCAGCT |
CAGTAGCTGG |
TCCCCAGGAG |
AGTACAGTGT |
GGGGGCCCCC |
GAGAGCACAG |
TGTATGGGGG |
TCCCCGGGGG |
|
18401 |
GTACAGTGTC |
TGGGGGCCCC |
CCAGGAGGAT |
GCAGCATGTG |
GGGGCCCCCC |
AGGAGGGTAC |
AGCGTGTGTG |
GGGCCCCCAG |
|
18481 |
GATCACAGGG |
TCTCAGCTCC |
TGGGCTCTTG |
GATTTGCAGC |
ACCACGACCA |
TCGCGTCTGG |
TCTGTTGGAA |
CGGGAGGTGC |
|
18561 |
TGCTGGGTAC |
CCTGGTCACT |
AGGGTGTGCT |
GGGAGGTGGG |
GGCCCCTCAT |
GGTGCCCATC |
CTTGGGGCCT |
GGCTGCAATT |
|
18641 |
TGACCCCAGG |
CCCAGGGTCT |
TCTGCCTTTC |
AGAGCCCTGG |
TGCCCTGAGA |
CGGGCAGCCA |
GGCAAATCCC |
AGGCAGGAGG |
|
18721 |
GCCAGTTAGG |
GCAGGGCCAG |
CCCAGGCAGG |
TTGCGAGAGT |
CCCTACTGGG |
ACGTGGACCA |
CACGCTGACC |
CCCACGGCCG |
|
18801 |
CCCCTGCAGG |
CCAGGATCCC |
TGAGCCAGGA |
CCCGGCACTG |
GCTTCCCTCC |
TGGGGACCCT |
CAGGCCTGTG |
TGAGACCTGG |
|
18881 |
GCTGCCCTGG |
GGTGAGGTGC |
CTGGGAGGAG |
AGCAGGGGCT |
GGGCCACCTT |
TTTCATGACC |
CTGCTAAGCC |
CACTGTGGGT |
|
18961 |
GGTGAGGAGG |
AGTACCCAGC |
AGGGGGAAGG |
GCCGCCAGAC |
CACTCGGCAT |
GGCTGAGGCC |
TCAGTACTCA |
GTACTGGGTA |
|
19041 |
CTCAGGTGGA |
CGCCCCTCCC |
ACTGCTCAGA |
TGCTGGGGAC |
AGGCTCAACT |
TCAGGCTTCA |
GCGTGAGCCC |
CGTCCCTGAC |
|
19121 |
CTGCAGAGCC |
CCCTTGCGTT |
GGGGCAGGAC |
AGCCCGGCGC |
CCTCGGGTCA |
GGCCATCCTC |
TGCGCTCTGC |
CGGGGCTGCT |
|
19201 |
GCATCGGCCT |
CTGCGTGCCT |
CCACTTTGGC |
CTCACGTGTC |
CCTACCCAGG |
ATGCGGGTCC |
TGCTGCCAAC |
ACCCAGATCC |
|
19281 |
CAGGGAAGGG |
GCTTGGGCTA |
GATCCTGGGC |
ACCAGTGCAG |
ACAGGAGTGT |
GGGGTGGGGC |
AAGGGCCCAG |
TGGCGGCTGT |
|
19361 |
GCCCGCTGAT |
GCAGAGCTGG |
GGCACCTTGT |
CCACAGGGTC |
TGCCCCACCA |
GAGACGGGCT |
GGGCCCAAGC |
TCAGACCTAT |
|
19441 |
GGGTGCAATT |
GGTGCCTCCT |
CACCAAGGTC |
TTTTTTATCT |
TTTTTTTTTT |
TTGGAGACAG |
AGTCTTGCTC |
TGTCGCCCAG |
|
19521 |
GCTGGAGTGC |
TGTGGTGCGA |
TCTCGGCTCA |
CTGCAACCTC |
CACCTCCCGG |
ATTCAAGCAA |
TTCTGCCTCA |
GCCTCCTGAG |
|
19601 |
TAGCTGGGAT |
TACAAGTGCG |
CGCCAGCATG |
CCCGGCTAAT |
TTTTGTATGT |
TTAGTAGAGA |
CGGGGGTTTC |
ACCATGTTGG |
|
19681 |
TCAGGCTGGT |
CTCAAACTCC |
TAACCTCATG |
ATCTGCCCAC |
CTCGGCCTCC |
CAAAGTGCTG |
GGATTACAAG |
CGTGAGCCAC |
|
19761 |
CGCGACCGGC |
CCAAGGTGCT |
TTTTTAAAGC |
TAGTGACTTC |
CTGTGCACAT |
GGGGTGGGTG |
TGTGGCAAGT |
TCTGGAAGCT |
|
19841 |
GCTGAGTCAG |
CCACTGGTCC |
ATTCTCGGAG |
CTGGGGCTCT |
GCACTGGGCA |
CATGAGCTCT |
GGGGCAGCCC |
GGGGCGGCCT |
|
19921 |
CCCACTGACT |
TCGCCCGGGA |
GGGGCCTCGG |
GGATGGCTCG |
GCAGCCAGTG |
TGTTCGCGGA |
GTCCTCGCCA |
ACCACCACGG |
|
20001 |
CTCCTCGCAG |
GGACAGTACG |
TGGGCAGCTT |
CCTGCACTTT |
CCCCTGCCAT |
TGTGAGAACA |
GTGTCCACCT |
GGGCAGGGTG |
|
20081 |
GGCAGCCCCA |
GGCCTGTGGG |
TTTCACCAGG |
GTGCTGGTGA |
TGGTTGGTGG |
CTAGCAGGGA |
CTGGGGGCAG |
CTGGGGGCCC |
|
20161 |
TGGCAGGCTG |
AGCTCTGCTC |
CCCGCGTGGT |
TCTGTGCTGG |
CATTTCGCGT |
GCCTGGCCTG |
AGCCTGGCCC |
GAGCCTGGCC |
|
20241 |
CTCCTGTGTC |
CTCACAGATG |
AGCATGTGGC |
GGCTCCTGGG |
CCTCTAGAAC |
CAACCATGGG |
CCAGGGTGCC |
CCAGGGGAGC |
|
20321 |
ACGGGAGGGT |
CCTGCCTTGT |
CAGCTTGCCT |
CCTACTCGTG |
AGGTTCCTGC |
AGTCAGTACC |
TGGGTGGGGT |
CCCACCTGCG |
|
20401 |
GCCATGGCAG |
GTGCAACAGA |
CGTGGTGGAG |
GGGACACTCC |
TGCCCAGGCC |
ATCTGCGGGA |
GGCTCAGCCC |
CGGGGGGTGC |
|
20481 |
CTCCCAGAGC |
TGCTGGGGGG |
CAGCATTTCA |
GGCTGGATAC |
ACCTGGGCCT |
GACCCGGGGG |
CGGGCATGGC |
CTGGGCAGCA |
|
20561 |
GCTGTAAGTG |
CGTCCCCGTG |
GTGGGGGCCA |
GCCAGGTCCC |
TGTGGCTCTG |
GGGTTGCGCC |
CCTCAGCTCA |
GGCCACACTT |
|
20641 |
GCCGTCTCCC |
TCCCAGGACA |
GGTCCCAGAA |
GAGGAGGCCA |
GTCACAATGG |
ACAGCGCCGG |
GGCCTCCCCA |
AGGCCGTGTG |
|
20721 |
TATGAACGGC |
ACAGAGGCGG |
CGCAGCTGAG |
CACCAAATCC |
AGGGCGGAGG |
GCCGGGCCCC |
CAACCCTGCC |
CGCAAGGCCT |
|
20801 |
GCTCCGCCAG |
CAGCAAGATC |
CGCCGGCTGT |
CGGCCTGCAA |
GCAGCAGTGA |
GGCTGGCCGC |
CTGCAGGTGG |
GGCGCGGCGG |
|
20881 |
GGCCCGGGTG |
GGGCATGTGG |
GGACAACGCC |
TGGATGCCAC |
AGCCAGCCGT |
GAGCATAGCC |
CGCGCTAGTC |
AGTCATGGTG |
|
20961 |
ACCGTCACGT |
GGCTGCGCGT |
GGTTGCCATG |
TGGCCTTTGG |
GTGGCTTGGC |
CACGTAGCGA |
TCCCCGTGGA |
GGGTGCCGTC |
|
21041 |
TCGGGGCCTG |
GTGTCTGGCC |
AGCGTGCTGG |
TCATGGAGGC |
CTACGTGTGG |
CGGGGCTCTG |
GGGGGGCGTG |
CCGTCCTCAC |
|
21121 |
AGCCACCTCT |
CAGAGTGGGT |
GCATTCCGAG |
GACCCTGCCC |
TGGGCCTGGC |
GCCCCCTCCC |
CATGCCCGCG |
CCGCTTCCAG |
|
21201 |
GAAAGGCTTA |
TGCTGGGCTC |
AGCCCAGAGG |
CTTTTGAGCA |
CCAGTGGGTG |
GTGGGTGGTG |
GGGAGGGGCC |
GCGGCCTCCA |
|
21281 |
TGGCTCTGCC |
GGGGTGCCGC |
AGGCTCTGAG |
CCAGCTGCCA |
AGTATGGCTG |
AGGCTGAGTC |
GTGCCGGACG |
CTGCCCTGTC |
|
21361 |
TCTCCCTGTG |
TGCCTGCCTC |
CTCTCCCAGC |
CCCAGCCCCA |
GCCCCGGGTG |
GGAGACGGAG |
TCCCAGAGGT |
GTCAGAGACC |
|
21441 |
CTTAAGTCAC |
CTGCCGAGGA |
TGCGGGGTGG |
ATGGGGGCCC |
GAGGCTGAAG |
CCCCTGCCTT |
GCCACAGCCC |
CTCTCCCAGG |
|
21521 |
TTTTGGGGGC |
CACCGCCTGA |
GTTACATGTC |
TGTCCCCCAA |
ATGGGTGCCC |
ACAGCCCATC |
CACCAGCGTC |
AGAGCCCGCC |
|
21601 |
AGGCCCCACT |
GCAAAAGGCC |
ACACAATGTA |
CCCCGGGAGT |
GACTCAAGGG |
TGGCCTTCCC |
TGGCCTCCCC |
TGCTGCCCCC |
|
21681 |
CAGGAGTCCG |
GTAGCCCCAT |
GACTGTACCT |
CAGCTTCTCC |
ATCCTCCCAG |
GGGCCCGCGG |
GAGGCGGAGA |
ACCGGTGCCC |
|
21761 |
AGGCTGACCT |
CTTCCGTCTT |
CCTTCCACCC |
TGCAGCCCGT |
GTCCAGGAGC |
CCCGCCAGGT |
GCCCGCGCCA |
GGCCCTCAGT |
|
21841 |
CTTCCTGCCG |
GTTCCGCCCG |
CCCTCCCGGA |
GAGGTGGCCG |
CCATGCTTCT |
GTGCCGACCA |
CGCCCCAGGA |
CCTCCGGAGC |
|
21921 |
GCCCTGCAGG |
GCCGGGCAGG |
GGGACAGCAG |
GGACCGGGCG |
CAGCCCTCCC |
CCCTCGGCCG |
CCCGGCAGTG |
CACGCGGCTT |
|
22001 |
GTTGACTTCG |
CAGCCCCGGG |
CGGAGCCTTC |
CCGGGCGGGC |
GTGGGAGGAG |
GGAGGCGGCC |
TCCATGCACT |
TTATGTGGAG |
|
22081 |
ACTACTGGCC |
CCGCCCGTGG |
CCTCGTGCTC |
CGCAGGGCGC |
CCAGCGCCGT |
CCGGCGGCCC |
CGCCGCAGAC |
CAGCTGGCGG |
|
22161 |
GTGTGGAGAC |
CAGGCTCCTG |
ACCCCGCCAT |
GCATGCAGCG |
CCACCTGGAA |
GCCGCGCGGC |
CGCTTTGGTT |
TTTTGTTTGG |
|
22241 |
TTGGTTCCAT |
TTTCTTTTTT |
TCTTTTTTTT |
TTTAAGAAAA |
AATAAAAGGT |
GGATTTGAGC |
TGTGGCTGTG |
AGGGGTGTTT |
|
22321 |
GGGAGCTGCT |
GGGTGGCAGG |
GGGGCTGTGG |
GGTCGGGCTC |
ACGTCGCGGC |
CGCCTTTGCG |
CTCTCGGGTC |
ACCCTGCTTT |
|
22401 |
GGCGGCCCGG |
CCGGAGGGCA |
GGACCCTCAC |
CTCTCCCCCA |
AGGCCACTGC |
GCTCTTGGGA |
CCCCAGAGAA |
AACCCGGAGC |
|
22481 |
AAGCAGGAGT |
GTGCGGTCAA |
TATTTATATC |
ATCCAGAAAA |
GAAAAACACG |
AGAAACGCCA |
TCGCGGGATG |
GTGCAGACGC |
|
22561 |
GGCGGGGACT |
CGGAGGGTGC |
CGTGCGGGCG |
AGGCCGCCCA |
AATTTGGCAA |
TAAATAAAGC |
TTGGGAAGCT |
TGGACCT |
|
|
|
|
|
|
|
|
|
|
|
|
>ref|Gene_ID:6794|STK11|NC_000019.9:1205797...1228433 (+)
GGCGTGTCGGGCGCGGAAGGGGGAGGCGGCCCGGGGCGCCCGCGAGTGAGGCGCGGGGCGGCGAAGGGAGCGCGGGTGGC
GGCACTTGCTGCCGCGGCCTTGGATGGGCTGGGCCCCCCTCGCCGCTCCGCCTCCTCCACACGCGCGGCGGCCGCGGCGA
GGGGGACGCGCCGCCCGGGGCCCGGCACCTTCGGGAACCCCCCGGCCCGGAGCCTGCGGCCTGCGCCGCCTCGGCCGCCG
GGAGCCCCGTGGAGCCCCCGCCGCCGCGCCGCCCCGCGGACCGGACGCTGAGGGCACTCGGGGCGGGGCGCGCGCTCGGG
CAGACGTTTGCGGGGAGGGGGGCGCCTGCCGGGCCCCGGCGACCACCTTGGGGGTCGCGGGCCGGCTCGGGGGGCGCCCA
GTGCGGGCCCTCGCGGGCGCCGGGCAGCGACCAGCCCTGAGCGGAGCTGTTGGCCGCGGCGGGAGGCCTCCCGGACGCCC
CCAGCCCCCCGAACGCTCGCCCGGGCCGGCGGGAGTCGGCGCCCCCCGGGAGGTCCGCTCGGTCGTCCGCGGCGGAGCGT
TTGCTCCTGGGACAGGCGGTGGGACCGGGGCGTCGCCGGAGACGCCCCCAGCGAAGTTGGGCTCTCCAGGTGTGGGGGTC
CCGGGGGGTAGCGACGTCGCGGACCCGGCCTGTGGGATGGGCGGCCCGGAGAAGACTGCGCTCGGCCGTGTTCATACTTG
TCCGTGGGCCTGAGGTCCCCGGAGGATGACCTAGCACTGAAAAGCCCCGGCCGGCCTCCCCAGGGTCCCCGAGGACGAAG
TTGACCCTGACCGGGCCGTCTCCCAGTTCTGAGGCCCGGGTCCCACTGGAACTCGCGTCTGAGCCGCCGTCCCGGACCCC
CGGTGCCCGCCGGTCCGCAGACCCTGCACCGGGCTTGGACTCGCAGCCGGGACTGACGTGTAGAACAATCGTTTCTGTTG
GAAGAAGGGTTTTTCCCTTCCTTTTGGGGTTTTTGTTGCCTTTTTTTTTTCTTTTTTCTTTGTAAAATTTTGGAGAAGGG
AAGTCGGAACACAAGGAAGGACCGCTCACCCGCGGACTCAGGGCTGGCGGCGGGACTCCAGGACCCTGGGTCCAGCATGG
AGGTGGTGGACCCGCAGCAGCTGGGCATGTTCACGGAGGGCGAGCTGATGTCGGTGGGTATGGACACGTTCATCCACCGC
ATCGACTCCACCGAGGTCATCTACCAGCCGCGCCGCAAGCGGGCCAAGCTCATCGGCAAGTACCTGATGGGGGACCTGCT
GGGGGAAGGCTCTTACGGCAAGGTGAAGGAGGTGCTGGACTCGGAGACGCTGTGCAGGAGGGCCGTCAAGATCCTCAAGA
AGAAGAAGTTGCGAAGGATCCCCAACGGGGAGGCCAACGTGAAGAAGTAAGTATGGCTTGCTGGGGTCGGGGCCGGGCCG
GGCCAGTCACGGTGCTGATGGTTCTGTCTTCCTTCCTTCTCTCCTCCCTCCCTCCCTTACTTCCTCTTAACACCCTGAGC
TGGACCCGTCTGGCGCCTGTGTCCTCCGTGCCAGGGAGAGCGTGGTTGGGGGCCTGCGTTACGGACTTTCACTCAGGCAA
GGCCAGTTGTCGCAGCGGGGCGTGCGTTTGCATGGGCTCTTGGACTCCAGTTAAAATGCCCTGGTAGCGAAACCCTCCTG
AGAAGGGAGCGGCCCCCAATCCCCTAAGACTAGCCCCTTGGCTCCCCCAGCTGTCCAAGGAGCAGAGGCGCCCAGTGGAA
TCAGCCTGTGTTTGTTTGGGCCCCGAGAGTTTGTGTGCGGCCGCCAACACGTTTTCTGCGCAGTGTGTGGCCGTTACCGG
GGCCAGGCGAAATGTGATTTGTTTATCCTGTCAGAGGGGAACCCTGGGCTGCCAAAAATAACTGTTTGCACCGGCTTATC
AGTCAGCAGGAGGGAAACGTAGCCTTTCCTCATTTGCCAGGGATGTGACGCTGGAAGCATCCCTGGCCCCCGGGGCTGGA
AGCCCTGCCCGAGGGGGACTGTGCCTCCCTCCCGAATTGCATCCGGAAGACCTTACTTTTCCAACTGACTTCTTCAGGCA
CGGGGCTGCCGCTGGGCATCCCGGACGCCTCTGCATCTGTGCGCGGAGAAGCTCCTACCTAGGGCAGCACTGGCCGGCCT
GAGCCTCTCCCAGCTGGTGGGGGTGGCCGGGGGTGTCCCTGCCTTATCGCAGCCAGACACGCTGCACCTGCCGCCGCCTG
GCGGGCCCTGCCCAGGCCCTGCTCCTTTCCCAGCCTTCTTAACTTTCAAAACTTTGCCTCCTGTTTCCAAGAAAGGACCT
TATCTGCTGGGCTAGGCCTCGAGGGACTGGCAAGGACACCCTGCGCAGGGCACCATGACCTTGGAAGGAGGTCCGGGGAG
GGGCTGCTGCGGTGTCTGCTCTCACCTTCCTCCTGCTCAGGGGCCCTGGGGCTCCTGCCGTGTCTGCTCTCACCTCTCTC
CTGCTCAGGGGCCCTGGGGCTCACGTACATTTTTTTTTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTTCCCCAGGCTGG
AGTGCAGTGGCGCGAACTGGGCTCACTGCAAGCTCCGCCTCCCGGGTTCATGCCATTCTCCTGCCTCAGCCTCCCGAGTA
GCTGGGACTACAGGCACCCGCCACCACGCCCGGCCAATTTTTTGTATTTTTCAGTAGAGACGGGGTTTCACCGTGTTAGC
CAGGATGGTCTCAATCTCCTGACCTCGTGATCCGCCCGCCTCGGCCTCCCAAAGTGCTGGTACTACAGGCGTGAGTCAAC
GCGTGCGGCCTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTTTCACTCTTGTTGCTCAGGCTGGAGTGCAGTGG
AGTGGTCTTGGCTCACTGCAATCTCCGCCCCCTGGGTTCAAGTGATTCTCGTGCCTCAGCCTCCCGAGTAGCTGGGATTA
CAGGTGCCTGCCACAGTGCCCAGCTAATTTTTTTTTTTTTTTTTTAGTAGAGACGGGGTTTCACCATCTTGGCCAGGTTG
GTCTTGAACTTCTGACCTCGTGATCCACCTGCCTCAGCCTCCCAAAGTGCTGGGATTAAAGGCGTGAGCCACCGCGCCCG
GCCAGCACGCTTCTTAATCAGCATGCAGGCTGTGACATGCGGAAACCAGGGGCACAGGCTCTGAAGTTTGTACTCTGGAG
CTGGAGCAGTCAGGGTTAAATGGGAGCGGCTGGGAAGGGTGTGTTTCCACGAGGCCTTTCTGATGTCTCAGTGCCCAGTC
TGGACCCGGGTAGAAGGTGTGGCCAGTGCCTTGAGTCAGTGGAGCAGTTGCCTGTGCCTGGTCTCTGTGAGATGGGTTGG
TCAGGGGCTAGGCAGAGCCTGTGCCTGGTCTCTGTGAGATGGGTTGGTCAGGGGCTAGGCAGAGCCTGTGCTGGGGGTAG
CAGGTGCCCTCTAAAGGGGCCAGTGACAGTCTCTCTCCCAGCAGTGAGAAACCCACGCTTAGGGGCCGGGCGCGGTGGCT
CACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGTGGGTGGATCGCCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAA
CATGGTGAAACCCCATCTCTACTAAAAATACAAAAGTTAGCCGAGTGTGGTGGCGTGTGCCTGTAATCCCAGCTACTCGG
GAGGCTGAGGCAGAACATTGCTGGAGCCTGGGAGGCGGAGCTTGCGGTGACCCGAGATCGCACCATTGCGCTCCAGCCTG
GGCGACACAGCGAGACTCTGTCTCAAAAATAAATAAATAAATAAATAAATAAATAAATAAATAAATAAATCTGGCTTGAG
TTTTGACAAATGTATATGCAGGGTCAATGGGAAGACAGACGCTGGAGGGTGGAAGCCTGACTGTGAGAGTGAGCCCCCTG
CTTTCCTGAACAGTCAGTGGAGGAGGTCCTGGGAGCTCAGGTGAGCACCTGAACGGTAGGGCAGAGCCTGAGGGTCTTGG
TGGAGACAGGCAAGAAGGTTGCAGGAACCTAGTCTGGCCCAGTGCCTGGGAGAACGGGAGGGAACACGGAGGCAGGGAGG
CAGAGGGGTTGGCAGGACCTGGACTGGACTGTGCGTCGCAGCTACCCACAGCTTGACCCCACTGCCTTGAAGTGAGTGAT
GCACCCTCACTAGTGTTCAGCGTCCAATTTCATCCTGGCCCTGAGTGTGTAACGGCTTTGCCCTTGCGGGGCCCCCTGGG
ATGAGGGGTGAGCCCTGTCCCTTCCTGGTCACTGTCTGCCATCAGGAGCTGCCCCGCTTACAGCTGTGATTCAGGAGCCA
CTGCATTTCCTCCAGCCCCCTGGGTGCTGCCAGGGGGTCCTCCTATTCTGGGAGCTGGTGTGTTCTGACTGGAGGCTGCC
ATGTGCAGAGTGCTGTCAAGGAGAAGGGGTGTCCACTGCCCAGCCCTGAGGCCCAAGGCCTTGGCCAGCCTTGCTGCCAG
CGCTGCAGGGAAAAAGCCTCCTTTGTGTGTGGGAAGTTTAATAAACTCCGCTCAGATTGTGTCTCGCAGCGAGTGTCTGG
AACCTTCCAGACAAGCCTCAGGCGTCCGGTCCTCCAGTTGGTGTGGAAAGCGTGGGCGATCACCAAGGGGGGTGGGTTGG
GGCAGATGGAGCCGGCGTGAGTCCCGTCTCTTCCCTTCCTTCCCAGAAAGGCAGCCCTGGAGTCCATGCCTTGTCCCGCT
CTCACCGGCAAAAAGTATAATCTTATTAGAAATAGGAAAGTTCCAAAAAGCATCAATGAGTTAAAAAGAGGGCTGGGCAT
GTTCGGTCATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGTGGATCACCCGAGGTTGGGAGTTAGCCTGACCAA
CATGGTGAAACCCTGTCTCTACTAAAAATACAAAATTAGCTGAGTGTGGTGGCGCACGCCTGTAATCCCAGCTACTCTGG
AGGCTGAGGCAGGAGAATCACTTGAACCCGGGAAGCAGAGGTTGCGGTGAGCCAAGACCATGCCATTGCACTCCAGCCTG
GGTAACAAGAGTGAAACTCCGTCTCGAAAAAAAAAAGGGCTGGGGCCGGGCGTGGTGGCTCACGCCTGTAATCCCAGCAC
TTTGGGAGGCCGAGGCGGTTTGATCACAAGGTCAGAAGTTTGAGACCAGCGTGGCCAACATGGTGAAACCCTCTCTCTAC
TAAAAATAGAAAAACTAGCCAGGTGTGGTGGCACATGCCAATAATCCCAGCTACTTCATCTGAGGTCAGGAGTTCAAGAC
CAGCCTGGCCAATATGGCGAAACTCCGTCTCTACTACAAATACAAAAATTAGCCAGGCGTGGTGGCGCGCGCCTGTAGTC
CAGCTACTGGGGAAGCTGAAGCAAGGAGAATCGCTTGAACCTGGGAGGCGGAGGTTGCGGTGAGCCGAGATCGCATCATT
GCATTCCAGGCTGGGCAAGCCTAGGAGAGAAGAGCGAAATTGTGTCTCAAAAAAACAATTAATTAAAATAAAATCAGTGC
CATAGGCTGTTTCTGGTAGGCAGTGGGTTCCTAGGGTGGAGCAGGGAAGGGCTGGAAAGGGTCGCCTGTGCCCAGCCCGA
CTCCCCGTGCTTCTCGGGGGACAGCACGGCTAGCTGCTGCTGCGGAGCCCACAGTGGGGTTCTGGGGGGGGGGGTGCAGG
CAGAAGGCCGCCATGCCTCCCTCCCCCTTTCCACCCCAGTGAGAGTGGGCTCGAAGGCAGGGAGTCTGCCCGCCTTGTGG
AGCCTCCGCAGAGGCACCCAGGGCTGCCGTGAGCGCACAGCCTGGCGGTGTCCCACGGCCCTGCCCTTTCCTGTCACTTC
CACCTGTTGCAAAACACTGTGCTTTCGTATCTTTTCTTTCTACCTGTTTGGAAATGTGAAAATCACTGCTGCCGTAGGAA
ACGGGCCCAGATCCGGGCTGTGGCTCTCCCATCCGCACCGCCCCCGCGGTGTCCAGCCAGGAGGTGGGAGGTGGGCGGCA
CTCAGTGTGCCTGGTTGCGGCGATGATTGGCAGATGCTTGGACCTATGGTAAAGAGGATTTTCGCGAGCTGGGAGTCAGT
CCTGGACTTTGTAGGTCTTTACATCCCAGGCGGCCTTTATGGGGTTCCAGCATCTGCTGAGGCCCCTGCGCCAGCCATGT
GAGGCCTGGGTGTCCTCGAGGCCTCTGTTTGTGCCCCTCTCTGGGCAGCGGGAGGGAGAGCTCTGAGACCCAGAGGGAGC
TCAGGGGCTGGGCAGCCGCAGAACAGCGGGGGTAATGGGTCCACTGGGGGTTCTGGGCTGTGCACACAGTGGGCTTCCGG
TGCCCAGCCAGCTGGGGCAGGCCTGGAATGTTGGTTCCTCTCTCAGGATCTGGGGCGCTGCTGTAGCTGTCGGGGAATCA
GTGAGGCGGCTGGACGGCCCGTATATCCCACAAACGCCACCGTATTGCTCAAACTGGACTCAATTTTCTTAACACCTTTT
TTTTTTTTTTTTTTTTTTTTTTTGGAGACAGGGTCTCACTGTATCGCCGAGGCTGGAGTGCAGTGGCGCAATCATAGCTC
TGGGCTCAGGTGACCCTCCTGCCCCCAAGGTAGCTGGGACTGCAGATGTGCACCACCACACCCGACTAGTTTTTTGTAGA
GATGGGGTTTCGCCATGTTGTCCAGGCTGGTCTCAAACTCCTAGACTCAAGCTATCCGCCTGCCTGGGCCTCCCAGAGTG
CTGGGATTACAGGTATGAGCCACTGCTTCGCCACGTTCACCTTTATTTACTTATTTATTTATTTTTGAGACGGAGTCTCG
CTCTGTCCCCCAGGCTGGAGTGCTGTGGCACGATCTTGGCTCACTGCAAGCTCCGCTTCAGCCTCCCAAGTAAGCTGGAA
CTACAGGTGCCTGCCACCAAGCCTGGCTAATTTTGTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCGTGTTAGCCAGT
ATGGTCTCGATCTCCTGACCTTGTGATCCGCCCGCCTCGGCCTCCCAAAGTCCTGGGATTACAGGCTTGAGTCACTGTGC
CCGGCCCACCTTTTTATTTTTTATTTTATAGAGACAAGGGCTTGCTGTGTTGCCCAGGCTGGTCTTGAACCCCTGACCTT
AAGTAATCCTCTCTGGCCTCCCAAAGTGCTGGGATTACAGGTGTAAGCCATAGTACTGGGCCTAAAGTTCACCTTTTTTT
TTTTTTTTTTTTTTTTTGAGATGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGTGATCTTGGCTCACTGCAA
GCTCTGCCTCCCGGGTTCACACCATTCTCCTGCCTCAGCCTCCCGAATAGCTGGGACTACAGGCGCCTGCCACCATGCCC
GGCTAATTTTTTTGTATTTTTAGTAGAGATGGGGTTTCACTGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGAT
CTGCCTGCCTCGGCCTCCCAAAGTGCTGGGGTTACAGGTGTGAGCCACCGCACCCGGCAAAGTTCACCTTTTTAAAGTGT
GTAATTCAGTGGCATATAGTACATTGACAGAGTTGCACAACTATCACCTCTATCAGCTTCCAGAACATTCTTGTTACCCC
AGAAGGAAACCCCGTCTCTGTCAGCCATCACTCCCCATTCCCTCCCCAGTCCCGGCACCCACGCATTCCCTTCCTGCCTC
TGGATTGGCCTGTCCTGAACATTTCACACGAGTGGTGTCACACACCGCGTGGCCTTTTGCGTCCGGCTTGTCTCACGGAG
TGTGCTGTCCTCAAGGGGCATCCGCGCCGTGGCCTGGGTCCGAACCTCTCTGCTGTTCACGGCTGCGTCACTTTCCAGTG
TGTGGAGGGCCACGCTGCGTTTGACTGCTCATCTGTGGCTGGACACTTGGGCTGCTCCCGCCTCTGCCTGTGAATTGTGG
CTGCTTTGGTGCACGTGTGCTCAGCCGGCGTCCCTCTAGAATCCTTGAGGGCCTTGTTTCAGCCACATCAGGAGGGATTC
AGGGACCAGGGCACGCGGGTCTGGAGCTGGGTGTTCCTGGGTCTCCATGTGCCTCCCAGTCCTGCTCTGAGCCGTGGGAG
GCCGGGGCGAGGGCCAGGCCCATCTCTTCCCTGTATGATCTGTTTCTAGGCAGACGGAGGCTCCTAGCCCCACCTCTCTG
TGAGCTTGAGTGGCGTTTATGACTCTCCTTCCTATTTCCTGTCCTGCTAATCAACAAGTCAGCTAAACAGTCCATGCTGC
CTGGGCAAGCCCAGTAGGCCCCTAACGTGGCACCTCGGAGCGGCTGGCGATGCCCCAAGAGCCGGGCTTCCCCCTCCTGG
AGGCTCTTCCTGTTCCTCGCCAAGCTCTTAGGTTTCGCTGGGCCTCCTCTTCTGCTCTTTTTCTGGCTGGAGACGTCAGA
GGAAGCCTGGCGATCTAGAGAAGCTGATGTGCACCCATCATCCCGGAGGTGACTGCCACCAGGCGGGGGTGGCTCCACCC
CCACTCCTCCCCTGGCATAAATCGGGGGACGCACGTGCCTGCGCAGAATGCCTTGGTCCCTTTTAATTAAACAGACAACC
CAGTGTCCCTTGGTCTATGCTGACCTGCTCAGGAGTGCCTGGGCTCTTCCACGTTTCAGCTGCTGTGTGTCCTGCTGCTG
TGAAGTGTCCCCGTTGAGGTGGAGGCAGGGCAGGGCGCCTTCGGTGAGGGCGAGTCCTCCTGTGCCCGTTTCCCCATCTG
TAGAATGATGGCTCATGGAGGAGACATGGTGTCGGCAGGTGGTGGCCGGCGCAGGGAGGTTTCCAGGAGGGAGTCCTCCA
CCCTCATTTGCTTTTAGGGCCGTGCAGCCTCCCGAGCGGCCCCCACGAGGCTCTGAGGCTGCATGCAGGTTGAGCTCCTG
GCCTCACTGCCCCTCCTCAGGGTTAGGACTGTGCTGGAGCCTGGGTGGGTGTGGGGTGGTCCCTGCACAGGCAGCAGGAG
GTGGGCCAGAGCGGTGCTGGACCTGAAGGCCCGTGGCTCCCTCAGCTCCACTGAGGAGGCTGGAATAGTGTCCTGGGCCA
CCTTCCCTGCCGGTAGCCGGCTCCTGCTGAGGGAGGGGGTGCTTTCGCCTCCTGGTGGAGCATCAGGCTCTTGGGGCCTG
TGCGTCCGAGCATCTGGCCTCTGCTGTCTGAAAACAGCACCTTCCCCGCCCCCCGGCCACCGCATCTCCTCTGAATAGAA
GGCAAGTCTTGCCTCCCAGGAATGGCCTGTGACCTTCATCAGCGGGGGAGGTTAGGGGCACACAGAGCCCTGGGGAACAA
GGGGATCTGGGGCTGAGCCGGGCCTCTCGGGCCCACCCCGAGCTCTCCTGAGCAGCCTGGCAGGCAGGAAGGCGCTGGGC
CCCGGGGCCTTTGCCGAGCCCAGCCTCACCCTCAGCGTCCCCCTCAATGCCCTGGGTGCCTGCCAGGCTGTGGACACAGG
CCCTGGCCAGTTCTATAAATAACCTTGCCGGGCCCTGCTGGGAATTGGTGCCACCACCACATAGCCCAGAGAGAACGGAA
ACACAGGGCTTCTCAGCGAGCAGACCAGGCCTGCGGTGACCAGTGGAAGTGGGGGACGCTTTCAGGGCTGGGCAGCCCGA
CAGGGCACCGGGCACAGCCAGGGGCCGGAACCAGTTGCTCACTGGCTCCGCTTCTGGGGGACTGTGTCCCTCTGTGCCCC
GTCCCCATCACACCTTGCTTTCCCTTCATCCTGCTCTCCTAGCCCCTCCCCAGACTGGCGGCCCCTTGTCCAGGCCCAGC
CCCAGCACAGCCTGCAGCCCTGGCAGAGCTCAGGCCTTGGCCTTCTGAGGTTGCCCTGAGGGCAGTGAGCAATGAGCCCT
GGGACTGGTGCACTGGGAGGGAAAGGTGAGCCAAGGCTTCCTGCAAGAGGCAGCCCTGAGCTGGGGGTGGGGAAGGCTGG
GTCGTGGGATACCCCTGACACCCCAAGTTTTTTTTTTGAGATGGAGTCTTGCTCTGTCACCCAGGCTGGAGTGCAGTGGT
GAGATCTCGACTCTCTGCAACCTCCGCCTCCCAGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTAC
AGGCGCCCATCACCACGCCCGGCTAATTTTTGTATTTTTAGTAGAGACAAGGTTTCACCATGTTGGCCAGGCTGGTTTCG
AACTCCTGACCTCAGGTGATCCACCTCGGCCTCCCATAGTGTCGGGATTACAGGCGTGAGTCACCGCGCCTGGCCCCCCA
GCTGTTTTTTATGCTCCATGCTTGGGCTTCCTGTTAAGAATTAAAAAAGAAAAAAAAAACTATGGAGATGGAATTTACAT
ACTGTACAACTCATTCGTTCACAGTGTACAATTCAGTGGCATTAAGTACATTCACACGGCTGTGCAACCACTACTTCTAA
TTCCAGAACGTTCGGTCACCCCAAAAGCAAGCCCCATTCCCATTGTGTCACTCTCCATCCCCTCCACCAGCTCCTGGCCA
CTCTGAATCCACTTCCTGGCTCTGGATTGGCTTGTCCTGGATATTGCATAGAAATGGGATCCTGTCGGCCGGGCGCGGTG
ACTCACGAGAGCAAGAGATCCAGACCATCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCTG
GGCGTGGTTGCGGGCACCTGTAGTCCCAGCGACTCAGGGGCTGAGTCAGGAGAAATCGCTTGAACCCGGGAGGCAGAGGT
TGCAGTGAGCTGAGATCATGCCATTGCACTCTGGCCTGGCGACAGAGTGAGACTCCGTCTCCAAAAAAAAAAAAACAAGA
AATGGGATCCTGTCATCCCAGCGTTTTCCGAGGCCGAGGTGGGCAGATGACTTGAGCCTAGTAGTTCAAACGAGACCAGC
CTGGGCAGCACGGTGAAACTGTCTCTACTAAAATACAAAAATTAGCTGGGCATGGTAGCACACGTCTGTAGTCCCAGCTA
CTTGCGGGGCTGAGATGGGAGGATCGCTTGAGCCTGGGAGGTGCACTCCAGCCTGGGCGACAGGGAAACCCTGTCTCAAA
AAAAAAAAAAAAAGTGCATCACACACTGTGTGTCCTTTAGTGTCTCACTGTGACATCCTCAAGGTGCAGCTAGGCTGTGG
CTCGAGTCAGAGCCTCACTGGTTTTTGTGGCTGAGTCTTGTTGAGTGCGTGGATGGGCTGTGCTGATCCTCGTCTGTGGA
AGGGCCCCTGGGTGGTTCCACATCTCGGCTGCTGTGCGTCCTGCTGCTGTGAGCATCTCGTGCTCCGTTTCTGCGTGGCG
TGTACTGTTCCTCAGGGTGTGTACCTGGGAGTGGAGCTGCTGGCTCACAGGGTAACAGACCTTTGGAGAAGCTGCAGACG
CTTCCACGCCCACCCACTGGGTGTGAGGACCTTGCTCCTCGTCATTTTTGTTTTTGTTTAATTTTTTCTTTTATGAGACA
GGGTCTTATTCTGTTGTCCAGGCTGGAGTGCAGTAGCACGATCACAGGTAACTACAGGCTCAAGTGATCCTCCCACCTGA
GCCTCCCGAGTAGCTAGGACTTGAGGCACGTACCTCCACACCTGGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCG
CCGTGTTGCTCAGGCTGGTCTCGAACTCCTGAGCTCAGGTGATCCACCCGCCTCGGCCTCCTATAGTGCTGGGAGAAATG
AAGTGTCTGCGACAGGGCGGCAGCTGCAGAGGGGGCTGTGCTCTCTGGCCTGTTGTGCCCCACCCTTGTGACAGGCAGGT
GGGCGTGGCCAACTGGGCGGCAGCTGCAGAGGGGGCAGTGACAGGCGGGTGGGTGTGGCAGGACCCCACAATGTCTCTTT
CTGTGGCGTCTCCTTCTTCGCCTGCCCCTTCCTATGGGCCATCCTTCCAGCTCACCTGCGGCCCACCCTCCAAGGAGTGG
GACCCTCGGAGTTGGGAGCCCTTGGCTGCGTGGGACTGTACTGTGTGACGGAGCCATCACCAGGGCTCCAACTCACCCTG
GCTCCTGCCACAGTCTGGGCTCCATCTGTGCTACCATTGCAGTAGTCTGGTTTCTAGGAAGCAAAACTGTTACTGAGTTA
CAAAGCTCAATTAAGAGTGTCCTTTGGGAGGCCGAGGCGGGCGGATCACAAGGTCAGGAGATCGAGACCATCCTGGCCAA
CATGGTGAAACCCTGTCTGTACTAAAATACAAAAAAATTAGCCGGCTGTGGTGACACGTGCCTGTAGTCCCAGCTACTCG
GGAGGCTGAGGCAGGGAAATCACTTGAACCTGGGAGGCAGAGGTTGCAGTGAGCTGAGATCGGGCCACCGTGCTCCAGCC
TAGGGACAGAGCAAGACTCTGTCTCAGAAAAAAAAAAAAGTGTCCTAACTGTGTCCTCCAAAGCCCTCGCCGGCCGATGA
CAGACTAGAGGGCGCTGTGCTCCCACCCCCTACCGCCCTGAGCCTGGACGCGTGGCCCCTGCAGGGCCCTTTCCCACAGC
ACTGTGAACTCACAGCTTCTCTCTAGGGAAGGGAGGAGGTACGCCACTTCCACAGGGAGATGGGGAGGCCGACTCCAGGG
ATCCAGGCCATCATCCTGACGTTGGGTCGGCTGATACACCCCTGTCCTCTCTGTCCCAGGGAAATTCAACTACTGAGGAG
GTTACGGCACAAAAATGTCATCCAGCTGGTGGATGTGTTATACAACGAAGAGAAGCAGAAAATATATCCTTTCCGGTGTT
GGGACCGCGGGGCCTCCGTGGGAGGGGCTGGGGCCCTGGGTCCGCCTGCCTCGAGGCCTGCTCCTCTTCCCGTCTCCTTG
AAGGAGACTGGCACACGAGGGCCGTGGCCTTCCCTGGTTCCCCGGAAGTCAGCCATTGTGGCAATGGCTGCGCAGCTTGC
TGAAAGGGGCCCTGAGCCCTGGCCCCTGTGTCTTGGGCCCGTGGGGTGTCAAGTCCCTTTTTTCTCAGAGTCTCCTCCCA
GGCTAACCAGGGGTGTAGCCACGGTCTGCCTGAGACAGGCCACGCGGGCTGACCGTTGTGGGCCATTTTGGTCGTGGCTG
GGCGTGTCCTCGTGTCATCTGTGGACACCCCCATGGGTCTTACGGGCACAGCCTCCCTACGGGGACTTTGCTTCCTAAGG
CCCTGTGCCCAGAGCAAGAGCCAGAAGTGGTCCTGAGGCTGGGGCTGTGTTCCCTGAGCCACGCGGTCAGGGGCCCTGGG
ACCGTCCTGCATGGGCCCGAGCCTGCTTGGGGGGGCGTCCAGGAGGCACCATCCCCCGCCCATGGGCAGGGTGGGGGACG
TGAGCCCCGCAGGAACGCTGCCCCAAGAGTCAGCCCTGTCCTCCCCTTCCCCGTAGGCTCCTTCCTCCTGGGACGCTGGG
GCCCCTGGGCCTTTTCAGAGGGGTGGCTGAGGGCAGGGTGGGCCCTGGTCCCGAGGAGGGGCAAGGTGGGTGCAGAGGGT
CCCTCCAGAGCCCCTTTTCTGGCCCCCGTGCTCCCTGGGCCTGTGAGTGGGGCCGCCCCCTGAGCTGTGTGTCCTTAGCG
CCCCACGTATATGGTGATGGAGTACTGCGTGTGTGGCATGCAGGAAATGCTGGACAGCGTGCCGGAGAAGCGTTTCCCAG
TGTGCCAGGCCCACGGGTGCGTGCGCGGGGCAGGGGCCAGGGTGGGGCGGGGGCCGGGGGCCAGGCAGGGCAGGCTCCTT
TCCGTGAGGCCACACTGCTTGTCCTGATATTCATTGACATGAAGGCCCAAGTTTTTTTGTTTTTTTGTTTTTTTGTGTTT
TTTTTCGAGATGGAGTCTCACTCTGTCGCCCAGGCTGGAGTGCAATGGTGCGATCTCGGCTCACTGCAAGCTCCGCCTCC
GAGGTTCACGCCATTCTTCTGCCTCAGCTTCCCGAGTAGCTGGGATTACAGGCGCCCGCCACCACGCCCGGCTAATTTTT
TGTATTTTTAGTAGAGACGGGGTTTCACCGTGTTAGCCAGGATGGTCTCAAACTCCTGACCTCGTGATCCGCCTGCCTCA
GCCTCCCAAAGTGCTGGGATTACAGGCATGAGCTACCACGCCCGGCCTTGTAAAGGCCCAAGTTTTTAAAAACAGTTTTG
GGGTCCCCCATGTGTGGCATCCACAGGCAGGGCTGCTGCCAACCTCCCGCCTCCATCTTTGCTGGGCCTGCTGCCTGAGG
CCAGTGGCCTGCTTCCAGCCCATCGCTGGCAGCCGCCTGCCCTGACCAGATCTCCTGGATGCAGGTCTGTGGCCTCAGAG
TCAGGGCCCCTTGCTGCTGCAGGACCACAGGGGCAGGGAGGGGCCTGCTGTTCCAGCAAGACTTTGGGGTGCAGCCGGCC
TGTGGCCCACAGGAAAATGAGACCTGTGGACATCCGGGGCCCTGCCAGACGTGGCTCGGCCGGACGAGGGTGGCCACTGC
AGGCGCAGGTGTGGCTCCCTGCTGGACCTAGCCTTTCCTCTGTCCTGTGTGCCTGGACTTCTGTGACTTCCCAGCTGGGC
CTGTGGTGTTTGGGAGGCTCCCAGGCAGCTGCAAAGGGGACCCCTGTGAGGGGCAGGGAGGCCTCGGCCCCAGGACGGGT
GTGTGCTGCCCGCAGGTACTTCTGTCAGCTGATTGACGGCCTGGAGTACCTGCATAGCCAGGGCATTGTGCACAAGGACA
TCAAGCCGGGGAACCTGCTGCTCACCACCGGTGGCACCCTCAAAATCTCCGACCTGGGCGTGGCCGAGGTAGGCACGTGC
TAGGGGGGGCCCTGGGGCGCCCCCTCCCGGGCACTCCCTGAGGGCTGCACGGCACCGCCACAGGCACTGCACCCGTTCGC
GGCGGACGACACCTGCCGGACCAGCCAGGGCTCCCCGGCTTTCCAGCCGCCCGAGATTGCCAACGGCCTGGACACCTTCT
CCGGCTTCAAGGTGGACATCTGGTCGGCTGGGGTCACCCTGTAAGTGCCCCGCCCCCCCGGGCACTCACCACACGCACAC
TCCGAGGGGCCTCTGCGTCTTGGGCAGCTGCCGGCCTGTGGGCGCAGGGCGTGGCCACCGGCCCAGACCCTCTCTGGCCA
CAGCCGCTAGGGGGTGCTTACTTTATGGAAATGTAACTCATACGGCAGATGGTGGTTCACCCGTGTGAAGTGCAGCCTGG
CCCGTCAGGGATCTTCACAGAGTGGCACGGCCGACCCTCCTCCCAGAGCCCCACAGGGAAGCTGGGCGGGTGACAGCAGC
TCCAGGCCCCTTCCCCGGGTGGGTCCAGAGGACACTCCCCTCCTACCCCGTAGCCTCCACTAGTGGAAGGTGGTGAAGAC
AGAGGTGTCCTTGAGTCCACAGGGCCTCTGGTCCAGCAGCCACGGGACGCCTCTGTCCCTGGGGTAGAGCTGGGGCTCCT
AGGGCGTCAACCACCTTGACTGACCACGCCTTTCTTCCCTCCCCTCGAAATGAAGCTACAACATCACCACGGGTCTGTAC
CCCTTCGAAGGGGACAACATCTACAAGTTGTTTGAGAACATCGGGAAGGGGAGCTACGCCATCCCGGGCGACTGTGGCCC
CCCGCTCTCTGACCTGCTGAAAGGTGGGAGCCTCATCCCTCTGCCCGCAGCCCCAGGGAGGCGGGGCTTTTGTGCAGAAA
TGTAGGGTTGGGGGTGTCAGGTGGGGGGCTATTGGCCCCGAGACCCCAGCAGGCATTGAGAGGACTGAGTGGAGAGGCCG
ACCTCCCCGCAGGGCCTGGTTTGCCAGGTCCCTCAGCTCCACCCTGCTTCTGGGCCCTGTTCACCCTCCGAACTCCCACC
CCAGAGGGCAGTGCTGCCCTGCGCCTCCCCCAGCCCCACCCTCGGGGGCTCCCTGGCTTGCAGGGTCTGTCAGGGTTGTC
CTGCTGCACTTCCTACGCATGGCAGCAGGTGGCACTGGCCGTCCGTCCATCTGCCCAGTGGCCTTGGGAGAACGGAACCG
CCCTGGCCGTCCAGCCCAGCCCTGTCTCCCTGCCAGCCGCGCACAGGCTGTCCCCGGCATGTCCCAGGAGTGGAGTGGCC
TCTGTCAGGGAGACCGCCTGTGCGCGGGGTCCCCCTTAGGAGCGTCCAGGTATCACCCAGGGCCTGACAACAGAGGCTGG
GCAGGCGGGGACGGTTGGTGGGGTCTCAGGCCTGTGCCCAGCTGACAGGCTCCTCGCCGGCTTCTCCTCAGGGATGCTTG
AGTACGAACCGGCCAAGAGGTTCTCCATCCGGCAGATCCGGCAGCACAGGTGAGCGGCCCCTGGGGGCAGTGGGGCCGAG
GCTGCAGGGAGGCCGGCCATGTGGGCAGCTGGTTGAGCGGGCGCTAGAGCAGGGCGTGGTGGGGGTGCCAGGCTGGGCTG
GGGCCAGACCCCGTGCAGCGCCCGCAGTTCTCGGGGCCCGAGTGGGGTCTCTGGGCAGTGTCCTGTTACCGGCCAGACCC
AGGCGCCTTGTCCGAACTGGGGTCTGAGTGAGGACATGCGTCCGTCCCTGCCCTAGGCATGGAGATGCGCCAGGAAGGGC
ACAGCTGGTCCCAAACACTGGCGAGAGCCTCTCTTTTTCCCCTCCTCCTGGGGCTCCCAGCAGCAGGGTGTGGCTGGGAT
CCAGCCCAGGGCCCCCAGCTCCATGACAGGGAAGACAGAGCAGCGGACGGGGTCAGCAGGCCCCACAGTGCCGCCTCCCT
CACTTCGTGGGCTCTGCTCCTCTGCACCAGCCCCTGGAGGCCCTTGAGCCGTCTGCTGGAGCCCCTCCGAGCCCCGAGGC
CACCCACTGAGACCGGCTCTGGGAGTGGGAGTGTCCGGACCCCTGAGGCGCTGGTGCTGATTGTGCCTTGGGGGTCTCTG
CACAGCTCGGGTCATCTGGGCGCCTGGCGGGGACTGGGGCTGCCCCCCGATAGCCTCCTGGGCTGGGATGTGCTCAGGGC
CCCCCAGACCCCCTTCTGGCCTTTGCTGGCTTTGCAGCCAGCATCCATCTGGTGGGTGCTGGCTTCTGAGTGCCACCTGG
GACACAGGCCTCAGGGTGGAGGGGACATCTGTCAGGCTTGGAGTCAGGTCAGCCTGCCTGCTCCTAGAGGACATGGCTGA
GCTTCTGTGGTCACAGCCACCCCTTGCACGGCCTGGTCCCAGCTCCTGAGTGTGTGGCAGGTACCCTGGGCCCAGAGGAG
CTGGGTCGGAAAACTGGACCGCCCTGGTGCCAGCCTGACAGGCGCCACTGCTTCTGGGCGTTTGCAGCTGGTTCCGGAAG
AAACATCCTCCGGCTGAAGCACCAGTGCCCATCCCACCGAGCCCAGACACCAAGGACCGGTGGCGCAGCATGACTGTGGT
GCCGTACTTGGAGGACCTGCACGGCGCGGACGAGGACGAGGACCTCTTCGACATCGAGGATGACATCATCTACACTCAGG
ACTTCACGGTGCCCGGTGAGTCTGGCGGGGGCCCCTGCCCGGCTCTGCTGACTCGGCCAGGATGTCCCACGGGAGCAGGG
TGCCTGCCTGTCTGCAACAAGGACAGCTTCTGCCCTCTGGTGGCCAATCCCACGTCCCCAAAGCCTCCAGCCCACCTGCA
GGCTGCCTCCGCCCTGCGGGCCGCTGGGACATGGCTGAAAGGTGTGGGGTCAGCGGGGGCACCAGCCCAGGCCTGTCTGG
CCAGGAGGGTTCCTCAGGCGTCTCTCCGGGTGCTGCCCAGCCAGGCACCACCCACCGGCCTTGGCCTGAGTCCCAGCAGG
AGCAGGCGGGGGAGCCCCAGGGTCGGGGGAGGGTAGGTGAGAGTCAGGGTGCAGGGTGGCCCCTCAGACAGCTGGCATGA
GAGAGGGTCCAGTGGCCCTCCCTCCCGTCGTCCCTGAGGCCTGCCCGCTGGCCCTGATGCCGGCCGCCCTTCTTCCCTAG
GTGGCGAGGAGGCGTCTGAGGCAGGGCTTAGAGCGGAGCGCGGCTTGCAGAAGAGCGAGGGCTCAGACCTTTCAGGAGAG
GAAGCCTCTCGGCCGGCGCCGCAGTAGTGCCTGAGGAGGAGCTCAGGGCCTTAGCGTAGGGGCGGCCCACATTGGCAGCC
AGCCCCTCCCCGCCATGCTCCCGGCTTGGCTGTGTTCGGCCCAGGGCTGGGCCGTGTCATAAAGAGTTTTGCAGTGTATC
TGCAGGGTGGATGCTTGCTGCGCTCGGGCTGGAGCCTGAGGGGGCTTTCTGCTTTACTGTTTCAGCGGGAAGTGGTGGGC
AGGGGCCGGCCTGAGAAGGGGGGTACGCCAGGCAGGTTGGGATGTGAGGACCCAGTGCACAGGGTCCACCCCCGGGCCCG
AGGGTCCCAGAATAGTGGGGGCCCTGCAGAGAGCCCCCCATTAGGTCCCTCAGCACTCCTGGGCCCCTCATCAAACCCCT
AGGCTCAGCTCAGTAGCTGGTCCCCAGGAGAGTACAGTGTGGGGGCCCCCGAGAGCACAGTGTATGGGGGTCCCCGGGGG
GTACAGTGTCTGGGGGCCCCCCAGGAGGATGCAGCATGTGGGGGCCCCCCAGGAGGGTACAGCGTGTGTGGGGCCCCCAG
GATCACAGGGTCTCAGCTCCTGGGCTCTTGGATTTGCAGCACCACGACCATCGCGTCTGGTCTGTTGGAACGGGAGGTGC
TGCTGGGTACCCTGGTCACTAGGGTGTGCTGGGAGGTGGGGGCCCCTCATGGTGCCCATCCTTGGGGCCTGGCTGCAATT
TGACCCCAGGCCCAGGGTCTTCTGCCTTTCAGAGCCCTGGTGCCCTGAGACGGGCAGCCAGGCAAATCCCAGGCAGGAGG
GCCAGTTAGGGCAGGGCCAGCCCAGGCAGGTTGCGAGAGTCCCTACTGGGACGTGGACCACACGCTGACCCCCACGGCCG
CCCCTGCAGGCCAGGATCCCTGAGCCAGGACCCGGCACTGGCTTCCCTCCTGGGGACCCTCAGGCCTGTGTGAGACCTGG
GCTGCCCTGGGGTGAGGTGCCTGGGAGGAGAGCAGGGGCTGGGCCACCTTTTTCATGACCCTGCTAAGCCCACTGTGGGT
GGTGAGGAGGAGTACCCAGCAGGGGGAAGGGCCGCCAGACCACTCGGCATGGCTGAGGCCTCAGTACTCAGTACTGGGTA
CTCAGGTGGACGCCCCTCCCACTGCTCAGATGCTGGGGACAGGCTCAACTTCAGGCTTCAGCGTGAGCCCCGTCCCTGAC
CTGCAGAGCCCCCTTGCGTTGGGGCAGGACAGCCCGGCGCCCTCGGGTCAGGCCATCCTCTGCGCTCTGCCGGGGCTGCT
GCATCGGCCTCTGCGTGCCTCCACTTTGGCCTCACGTGTCCCTACCCAGGATGCGGGTCCTGCTGCCAACACCCAGATCC
CAGGGAAGGGGCTTGGGCTAGATCCTGGGCACCAGTGCAGACAGGAGTGTGGGGTGGGGCAAGGGCCCAGTGGCGGCTGT
GCCCGCTGATGCAGAGCTGGGGCACCTTGTCCACAGGGTCTGCCCCACCAGAGACGGGCTGGGCCCAAGCTCAGACCTAT
GGGTGCAATTGGTGCCTCCTCACCAAGGTCTTTTTTATCTTTTTTTTTTTTTGGAGACAGAGTCTTGCTCTGTCGCCCAG
GCTGGAGTGCTGTGGTGCGATCTCGGCTCACTGCAACCTCCACCTCCCGGATTCAAGCAATTCTGCCTCAGCCTCCTGAG
TAGCTGGGATTACAAGTGCGCGCCAGCATGCCCGGCTAATTTTTGTATGTTTAGTAGAGACGGGGGTTTCACCATGTTGG
TCAGGCTGGTCTCAAACTCCTAACCTCATGATCTGCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAAGCGTGAGCCAC
CGCGACCGGCCCAAGGTGCTTTTTTAAAGCTAGTGACTTCCTGTGCACATGGGGTGGGTGTGTGGCAAGTTCTGGAAGCT
GCTGAGTCAGCCACTGGTCCATTCTCGGAGCTGGGGCTCTGCACTGGGCACATGAGCTCTGGGGCAGCCCGGGGCGGCCT
CCCACTGACTTCGCCCGGGAGGGGCCTCGGGGATGGCTCGGCAGCCAGTGTGTTCGCGGAGTCCTCGCCAACCACCACGG
CTCCTCGCAGGGACAGTACGTGGGCAGCTTCCTGCACTTTCCCCTGCCATTGTGAGAACAGTGTCCACCTGGGCAGGGTG
GGCAGCCCCAGGCCTGTGGGTTTCACCAGGGTGCTGGTGATGGTTGGTGGCTAGCAGGGACTGGGGGCAGCTGGGGGCCC
TGGCAGGCTGAGCTCTGCTCCCCGCGTGGTTCTGTGCTGGCATTTCGCGTGCCTGGCCTGAGCCTGGCCCGAGCCTGGCC
CTCCTGTGTCCTCACAGATGAGCATGTGGCGGCTCCTGGGCCTCTAGAACCAACCATGGGCCAGGGTGCCCCAGGGGAGC
ACGGGAGGGTCCTGCCTTGTCAGCTTGCCTCCTACTCGTGAGGTTCCTGCAGTCAGTACCTGGGTGGGGTCCCACCTGCG
GCCATGGCAGGTGCAACAGACGTGGTGGAGGGGACACTCCTGCCCAGGCCATCTGCGGGAGGCTCAGCCCCGGGGGGTGC
CTCCCAGAGCTGCTGGGGGGCAGCATTTCAGGCTGGATACACCTGGGCCTGACCCGGGGGCGGGCATGGCCTGGGCAGCA
GCTGTAAGTGCGTCCCCGTGGTGGGGGCCAGCCAGGTCCCTGTGGCTCTGGGGTTGCGCCCCTCAGCTCAGGCCACACTT
GCCGTCTCCCTCCCAGGACAGGTCCCAGAAGAGGAGGCCAGTCACAATGGACAGCGCCGGGGCCTCCCCAAGGCCGTGTG
TATGAACGGCACAGAGGCGGCGCAGCTGAGCACCAAATCCAGGGCGGAGGGCCGGGCCCCCAACCCTGCCCGCAAGGCCT
GCTCCGCCAGCAGCAAGATCCGCCGGCTGTCGGCCTGCAAGCAGCAGTGAGGCTGGCCGCCTGCAGGTGGGGCGCGGCGG
GGCCCGGGTGGGGCATGTGGGGACAACGCCTGGATGCCACAGCCAGCCGTGAGCATAGCCCGCGCTAGTCAGTCATGGTG
ACCGTCACGTGGCTGCGCGTGGTTGCCATGTGGCCTTTGGGTGGCTTGGCCACGTAGCGATCCCCGTGGAGGGTGCCGTC
TCGGGGCCTGGTGTCTGGCCAGCGTGCTGGTCATGGAGGCCTACGTGTGGCGGGGCTCTGGGGGGGCGTGCCGTCCTCAC
AGCCACCTCTCAGAGTGGGTGCATTCCGAGGACCCTGCCCTGGGCCTGGCGCCCCCTCCCCATGCCCGCGCCGCTTCCAG
GAAAGGCTTATGCTGGGCTCAGCCCAGAGGCTTTTGAGCACCAGTGGGTGGTGGGTGGTGGGGAGGGGCCGCGGCCTCCA
TGGCTCTGCCGGGGTGCCGCAGGCTCTGAGCCAGCTGCCAAGTATGGCTGAGGCTGAGTCGTGCCGGACGCTGCCCTGTC
TCTCCCTGTGTGCCTGCCTCCTCTCCCAGCCCCAGCCCCAGCCCCGGGTGGGAGACGGAGTCCCAGAGGTGTCAGAGACC
CTTAAGTCACCTGCCGAGGATGCGGGGTGGATGGGGGCCCGAGGCTGAAGCCCCTGCCTTGCCACAGCCCCTCTCCCAGG
TTTTGGGGGCCACCGCCTGAGTTACATGTCTGTCCCCCAAATGGGTGCCCACAGCCCATCCACCAGCGTCAGAGCCCGCC
AGGCCCCACTGCAAAAGGCCACACAATGTACCCCGGGAGTGACTCAAGGGTGGCCTTCCCTGGCCTCCCCTGCTGCCCCC
CAGGAGTCCGGTAGCCCCATGACTGTACCTCAGCTTCTCCATCCTCCCAGGGGCCCGCGGGAGGCGGAGAACCGGTGCCC
AGGCTGACCTCTTCCGTCTTCCTTCCACCCTGCAGCCCGTGTCCAGGAGCCCCGCCAGGTGCCCGCGCCAGGCCCTCAGT
CTTCCTGCCGGTTCCGCCCGCCCTCCCGGAGAGGTGGCCGCCATGCTTCTGTGCCGACCACGCCCCAGGACCTCCGGAGC
GCCCTGCAGGGCCGGGCAGGGGGACAGCAGGGACCGGGCGCAGCCCTCCCCCCTCGGCCGCCCGGCAGTGCACGCGGCTT
GTTGACTTCGCAGCCCCGGGCGGAGCCTTCCCGGGCGGGCGTGGGAGGAGGGAGGCGGCCTCCATGCACTTTATGTGGAG
ACTACTGGCCCCGCCCGTGGCCTCGTGCTCCGCAGGGCGCCCAGCGCCGTCCGGCGGCCCCGCCGCAGACCAGCTGGCGG
GTGTGGAGACCAGGCTCCTGACCCCGCCATGCATGCAGCGCCACCTGGAAGCCGCGCGGCCGCTTTGGTTTTTTGTTTGG
TTGGTTCCATTTTCTTTTTTTCTTTTTTTTTTTAAGAAAAAATAAAAGGTGGATTTGAGCTGTGGCTGTGAGGGGTGTTT
GGGAGCTGCTGGGTGGCAGGGGGGCTGTGGGGTCGGGCTCACGTCGCGGCCGCCTTTGCGCTCTCGGGTCACCCTGCTTT
GGCGGCCCGGCCGGAGGGCAGGACCCTCACCTCTCCCCCAAGGCCACTGCGCTCTTGGGACCCCAGAGAAAACCCGGAGC
AAGCAGGAGTGTGCGGTCAATATTTATATCATCCAGAAAAGAAAAACACGAGAAACGCCATCGCGGGATGGTGCAGACGC
GGCGGGGACTCGGAGGGTGCCGTGCGGGCGAGGCCGCCCAAATTTGGCAATAAATAAAGCTTGGGAAGCTTGGACCT
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Primary source |
RefSeq : NM_000455.4 (GI:58530881)
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Name |
Serine/threonine kinase 11 (STK11)
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Type of transcript |
mRNA
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Organism |
Homo sapiens
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Length |
3286 nt
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Map |
19p13.3
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Location |
Chromosome 19 (NC_000019.9) strand : +
1205797...1207201 | 1218415...1218498 | 1219322...1219411 | 1220371...1220503 |
1220579...1220715 | 1221211...1221338 | 1221947...1222004 | 1222983...1223170 |
1226452...1226661 | 1227591...1228433 |
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Exon(s) |
Start |
End |
Length |
is coding |
Exon 1
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1
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1405
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1405
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1
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Exon 2
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1406
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1489
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84
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1
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Exon 3
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1490
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1579
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90
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1
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Exon 4
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1580
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1712
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133
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1
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Exon 5
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1713
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1849
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137
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1
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Exon 6
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1850
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1977
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128
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1
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Exon 7
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1978
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2035
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58
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1
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Exon 8
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2036
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2223
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188
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1
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Exon 9
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2224
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2433
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210
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1
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Exon 10
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2434
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3276
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843
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1
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Primary source |
NCBI : CCDS45896
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Nucleotide |
STK11, mRNA isoform 1[NM_000455.4] : 1116...2417
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Length |
1302
|
Location |
Chromosome 19 (NC_000019.9) strand : +
1206912...1207201 | 1218415...1218498 | 1219322...1219411 | 1220371...1220503 |
1220579...1220715 | 1221211...1221338 | 1221947...1222004 | 1222983...1223170 |
1226452...1226645 |
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Start codon |
1
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Translation |
NP_000446.1 |
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1 |
GCGTGTCGGG |
CGCGGAAGGG |
GGAGGCGGCC |
CGGGGCGCCC |
GCGAGTGAGG |
CGCGGGGCGG |
CGAAGGGAGC |
GCGGGTGGCG |
|
81 |
GCACTTGCTG |
CCGCGGCCTT |
GGATGGGCTG |
GGCCCCCCTC |
GCCGCTCCGC |
CTCCTCCACA |
CGCGCGGCGG |
CCGCGGCGAG |
|
161 |
GGGGACGCGC |
CGCCCGGGGC |
CCGGCACCTT |
CGGGAACCCC |
CCGGCCCGGA |
GCCTGCGGCC |
TGCGCCGCCT |
CGGCCGCCGG |
|
241 |
GAGCCCCGTG |
GAGCCCCCGC |
CGCCGCGCCG |
CCCCGCGGAC |
CGGACGCTGA |
GGGCACTCGG |
GGCGGGGCGC |
GCGCTCGGGC |
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321 |
AGACGTTTGC |
GGGGAGGGGG |
GCGCCTGCCG |
GGCCCCGGCG |
ACCACCTTGG |
GGGTCGCGGG |
CCGGCTCGGG |
GGGCGCCCAG |
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401 |
TGCGGGCCCT |
CGCGGGCGCC |
GGGCAGCGAC |
CAGCCCTGAG |
CGGAGCTGTT |
GGCCGCGGCG |
GGAGGCCTCC |
CGGACGCCCC |
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481 |
CAGCCCCCCG |
AACGCTCGCC |
CGGGCCGGCG |
GGAGTCGGCG |
CCCCCCGGGA |
GGTCCGCTCG |
GTCGTCCGCG |
GCGGAGCGTT |
|
561 |
TGCTCCTGGG |
ACAGGCGGTG |
GGACCGGGGC |
GTCGCCGGAG |
ACGCCCCCAG |
CGAAGTTGGG |
CTCTCCAGGT |
GTGGGGGTCC |
|
641 |
CGGGGGGTAG |
CGACGTCGCG |
GACCCGGCCT |
GTGGGATGGG |
CGGCCCGGAG |
AAGACTGCGC |
TCGGCCGTGT |
TCATACTTGT |
|
721 |
CCGTGGGCCT |
GAGGTCCCCG |
GAGGATGACC |
TAGCACTGAA |
AAGCCCCGGC |
CGGCCTCCCC |
AGGGTCCCCG |
AGGACGAAGT |
|
801 |
TGACCCTGAC |
CGGGCCGTCT |
CCCAGTTCTG |
AGGCCCGGGT |
CCCACTGGAA |
CTCGCGTCTG |
AGCCGCCGTC |
CCGGACCCCC |
|
881 |
GGTGCCCGCC |
GGTCCGCAGA |
CCCTGCACCG |
GGCTTGGACT |
CGCAGCCGGG |
ACTGACGTGT |
AGAACAATCG |
TTTCTGTTGG |
|
961 |
AAGAAGGGTT |
TTTCCCTTCC |
TTTTGGGGTT |
TTTGTTGCCT |
TTTTTTTTTC |
TTTTTTCTTT |
GTAAAATTTT |
GGAGAAGGGA |
|
1041 |
AGTCGGAACA |
CAAGGAAGGA |
CCGCTCACCC |
GCGGACTCAG |
GGCTGGCGGC |
GGGACTCCAG |
GACCCTGGGT |
CCAGCATGGA |
|
1121 |
GGTGGTGGAC |
CCGCAGCAGC |
TGGGCATGTT |
CACGGAGGGC |
GAGCTGATGT |
CGGTGGGTAT |
GGACACGTTC |
ATCCACCGCA |
|
1201 |
TCGACTCCAC |
CGAGGTCATC |
TACCAGCCGC |
GCCGCAAGCG |
GGCCAAGCTC |
ATCGGCAAGT |
ACCTGATGGG |
GGACCTGCTG |
|
1281 |
GGGGAAGGCT |
CTTACGGCAA |
GGTGAAGGAG |
GTGCTGGACT |
CGGAGACGCT |
GTGCAGGAGG |
GCCGTCAAGA |
TCCTCAAGAA |
|
1361 |
GAAGAAGTTG |
CGAAGGATCC |
CCAACGGGGA |
GGCCAACGTG |
AAGAAGGAAA |
TTCAACTACT |
GAGGAGGTTA |
CGGCACAAAA |
|
1441 |
ATGTCATCCA |
GCTGGTGGAT |
GTGTTATACA |
ACGAAGAGAA |
GCAGAAAATG |
TATATGGTGA |
TGGAGTACTG |
CGTGTGTGGC |
|
1521 |
ATGCAGGAAA |
TGCTGGACAG |
CGTGCCGGAG |
AAGCGTTTCC |
CAGTGTGCCA |
GGCCCACGGG |
TACTTCTGTC |
AGCTGATTGA |
|
1601 |
CGGCCTGGAG |
TACCTGCATA |
GCCAGGGCAT |
TGTGCACAAG |
GACATCAAGC |
CGGGGAACCT |
GCTGCTCACC |
ACCGGTGGCA |
|
1681 |
CCCTCAAAAT |
CTCCGACCTG |
GGCGTGGCCG |
AGGCACTGCA |
CCCGTTCGCG |
GCGGACGACA |
CCTGCCGGAC |
CAGCCAGGGC |
|
1761 |
TCCCCGGCTT |
TCCAGCCGCC |
CGAGATTGCC |
AACGGCCTGG |
ACACCTTCTC |
CGGCTTCAAG |
GTGGACATCT |
GGTCGGCTGG |
|
1841 |
GGTCACCCTC |
TACAACATCA |
CCACGGGTCT |
GTACCCCTTC |
GAAGGGGACA |
ACATCTACAA |
GTTGTTTGAG |
AACATCGGGA |
|
1921 |
AGGGGAGCTA |
CGCCATCCCG |
GGCGACTGTG |
GCCCCCCGCT |
CTCTGACCTG |
CTGAAAGGGA |
TGCTTGAGTA |
CGAACCGGCC |
|
2001 |
AAGAGGTTCT |
CCATCCGGCA |
GATCCGGCAG |
CACAGCTGGT |
TCCGGAAGAA |
ACATCCTCCG |
GCTGAAGCAC |
CAGTGCCCAT |
|
2081 |
CCCACCGAGC |
CCAGACACCA |
AGGACCGGTG |
GCGCAGCATG |
ACTGTGGTGC |
CGTACTTGGA |
GGACCTGCAC |
GGCGCGGACG |
|
2161 |
AGGACGAGGA |
CCTCTTCGAC |
ATCGAGGATG |
ACATCATCTA |
CACTCAGGAC |
TTCACGGTGC |
CCGGACAGGT |
CCCAGAAGAG |
|
2241 |
GAGGCCAGTC |
ACAATGGACA |
GCGCCGGGGC |
CTCCCCAAGG |
CCGTGTGTAT |
GAACGGCACA |
GAGGCGGCGC |
AGCTGAGCAC |
|
2321 |
CAAATCCAGG |
GCGGAGGGCC |
GGGCCCCCAA |
CCCTGCCCGC |
AAGGCCTGCT |
CCGCCAGCAG |
CAAGATCCGC |
CGGCTGTCGG |
|
2401 |
CCTGCAAGCA |
GCAGTGAGGC |
TGGCCGCCTG |
CAGCCCGTGT |
CCAGGAGCCC |
CGCCAGGTGC |
CCGCGCCAGG |
CCCTCAGTCT |
|
2481 |
TCCTGCCGGT |
TCCGCCCGCC |
CTCCCGGAGA |
GGTGGCCGCC |
ATGCTTCTGT |
GCCGACCACG |
CCCCAGGACC |
TCCGGAGCGC |
|
2561 |
CCTGCAGGGC |
CGGGCAGGGG |
GACAGCAGGG |
ACCGGGCGCA |
GCCCTCCCCC |
CTCGGCCGCC |
CGGCAGTGCA |
CGCGGCTTGT |
|
2641 |
TGACTTCGCA |
GCCCCGGGCG |
GAGCCTTCCC |
GGGCGGGCGT |
GGGAGGAGGG |
AGGCGGCCTC |
CATGCACTTT |
ATGTGGAGAC |
|
2721 |
TACTGGCCCC |
GCCCGTGGCC |
TCGTGCTCCG |
CAGGGCGCCC |
AGCGCCGTCC |
GGCGGCCCCG |
CCGCAGACCA |
GCTGGCGGGT |
|
2801 |
GTGGAGACCA |
GGCTCCTGAC |
CCCGCCATGC |
ATGCAGCGCC |
ACCTGGAAGC |
CGCGCGGCCG |
CTTTGGTTTT |
TTGTTTGGTT |
|
2881 |
GGTTCCATTT |
TCTTTTTTTC |
TTTTTTTTTT |
TAAGAAAAAA |
TAAAAGGTGG |
ATTTGAGCTG |
TGGCTGTGAG |
GGGTGTTTGG |
|
2961 |
GAGCTGCTGG |
GTGGCAGGGG |
GGCTGTGGGG |
TCGGGCTCAC |
GTCGCGGCCG |
CCTTTGCGCT |
CTCGGGTCAC |
CCTGCTTTGG |
|
3041 |
CGGCCCGGCC |
GGAGGGCAGG |
ACCCTCACCT |
CTCCCCCAAG |
GCCACTGCGC |
TCTTGGGACC |
CCAGAGAAAA |
CCCGGAGCAA |
|
3121 |
GCAGGAGTGT |
GCGGTCAATA |
TTTATATCAT |
CCAGAAAAGA |
AAAACACGAG |
AAACGCCATC |
GCGGGATGGT |
GCAGACGCGG |
|
3201 |
CGGGGACTCG |
GAGGGTGCCG |
TGCGGGCGAG |
GCCGCCCAAA |
TTTGGCAATA |
AATAAAGCTT |
GGGAAGCTTG |
GACCTGAAAA |
|
3281 |
AAAAAA |
|
|
|
|
|
|
|
|
|
|
|
|
>gi|58530881|ref|NM_000455.4|Serine/threonine kinase 11 (STK11)
GCGTGTCGGGCGCGGAAGGGGGAGGCGGCCCGGGGCGCCCGCGAGTGAGGCGCGGGGCGGCGAAGGGAGCGCGGGTGGCG
GCACTTGCTGCCGCGGCCTTGGATGGGCTGGGCCCCCCTCGCCGCTCCGCCTCCTCCACACGCGCGGCGGCCGCGGCGAG
GGGGACGCGCCGCCCGGGGCCCGGCACCTTCGGGAACCCCCCGGCCCGGAGCCTGCGGCCTGCGCCGCCTCGGCCGCCGG
GAGCCCCGTGGAGCCCCCGCCGCCGCGCCGCCCCGCGGACCGGACGCTGAGGGCACTCGGGGCGGGGCGCGCGCTCGGGC
AGACGTTTGCGGGGAGGGGGGCGCCTGCCGGGCCCCGGCGACCACCTTGGGGGTCGCGGGCCGGCTCGGGGGGCGCCCAG
TGCGGGCCCTCGCGGGCGCCGGGCAGCGACCAGCCCTGAGCGGAGCTGTTGGCCGCGGCGGGAGGCCTCCCGGACGCCCC
CAGCCCCCCGAACGCTCGCCCGGGCCGGCGGGAGTCGGCGCCCCCCGGGAGGTCCGCTCGGTCGTCCGCGGCGGAGCGTT
TGCTCCTGGGACAGGCGGTGGGACCGGGGCGTCGCCGGAGACGCCCCCAGCGAAGTTGGGCTCTCCAGGTGTGGGGGTCC
CGGGGGGTAGCGACGTCGCGGACCCGGCCTGTGGGATGGGCGGCCCGGAGAAGACTGCGCTCGGCCGTGTTCATACTTGT
CCGTGGGCCTGAGGTCCCCGGAGGATGACCTAGCACTGAAAAGCCCCGGCCGGCCTCCCCAGGGTCCCCGAGGACGAAGT
TGACCCTGACCGGGCCGTCTCCCAGTTCTGAGGCCCGGGTCCCACTGGAACTCGCGTCTGAGCCGCCGTCCCGGACCCCC
GGTGCCCGCCGGTCCGCAGACCCTGCACCGGGCTTGGACTCGCAGCCGGGACTGACGTGTAGAACAATCGTTTCTGTTGG
AAGAAGGGTTTTTCCCTTCCTTTTGGGGTTTTTGTTGCCTTTTTTTTTTCTTTTTTCTTTGTAAAATTTTGGAGAAGGGA
AGTCGGAACACAAGGAAGGACCGCTCACCCGCGGACTCAGGGCTGGCGGCGGGACTCCAGGACCCTGGGTCCAGCATGGA
GGTGGTGGACCCGCAGCAGCTGGGCATGTTCACGGAGGGCGAGCTGATGTCGGTGGGTATGGACACGTTCATCCACCGCA
TCGACTCCACCGAGGTCATCTACCAGCCGCGCCGCAAGCGGGCCAAGCTCATCGGCAAGTACCTGATGGGGGACCTGCTG
GGGGAAGGCTCTTACGGCAAGGTGAAGGAGGTGCTGGACTCGGAGACGCTGTGCAGGAGGGCCGTCAAGATCCTCAAGAA
GAAGAAGTTGCGAAGGATCCCCAACGGGGAGGCCAACGTGAAGAAGGAAATTCAACTACTGAGGAGGTTACGGCACAAAA
ATGTCATCCAGCTGGTGGATGTGTTATACAACGAAGAGAAGCAGAAAATGTATATGGTGATGGAGTACTGCGTGTGTGGC
ATGCAGGAAATGCTGGACAGCGTGCCGGAGAAGCGTTTCCCAGTGTGCCAGGCCCACGGGTACTTCTGTCAGCTGATTGA
CGGCCTGGAGTACCTGCATAGCCAGGGCATTGTGCACAAGGACATCAAGCCGGGGAACCTGCTGCTCACCACCGGTGGCA
CCCTCAAAATCTCCGACCTGGGCGTGGCCGAGGCACTGCACCCGTTCGCGGCGGACGACACCTGCCGGACCAGCCAGGGC
TCCCCGGCTTTCCAGCCGCCCGAGATTGCCAACGGCCTGGACACCTTCTCCGGCTTCAAGGTGGACATCTGGTCGGCTGG
GGTCACCCTCTACAACATCACCACGGGTCTGTACCCCTTCGAAGGGGACAACATCTACAAGTTGTTTGAGAACATCGGGA
AGGGGAGCTACGCCATCCCGGGCGACTGTGGCCCCCCGCTCTCTGACCTGCTGAAAGGGATGCTTGAGTACGAACCGGCC
AAGAGGTTCTCCATCCGGCAGATCCGGCAGCACAGCTGGTTCCGGAAGAAACATCCTCCGGCTGAAGCACCAGTGCCCAT
CCCACCGAGCCCAGACACCAAGGACCGGTGGCGCAGCATGACTGTGGTGCCGTACTTGGAGGACCTGCACGGCGCGGACG
AGGACGAGGACCTCTTCGACATCGAGGATGACATCATCTACACTCAGGACTTCACGGTGCCCGGACAGGTCCCAGAAGAG
GAGGCCAGTCACAATGGACAGCGCCGGGGCCTCCCCAAGGCCGTGTGTATGAACGGCACAGAGGCGGCGCAGCTGAGCAC
CAAATCCAGGGCGGAGGGCCGGGCCCCCAACCCTGCCCGCAAGGCCTGCTCCGCCAGCAGCAAGATCCGCCGGCTGTCGG
CCTGCAAGCAGCAGTGAGGCTGGCCGCCTGCAGCCCGTGTCCAGGAGCCCCGCCAGGTGCCCGCGCCAGGCCCTCAGTCT
TCCTGCCGGTTCCGCCCGCCCTCCCGGAGAGGTGGCCGCCATGCTTCTGTGCCGACCACGCCCCAGGACCTCCGGAGCGC
CCTGCAGGGCCGGGCAGGGGGACAGCAGGGACCGGGCGCAGCCCTCCCCCCTCGGCCGCCCGGCAGTGCACGCGGCTTGT
TGACTTCGCAGCCCCGGGCGGAGCCTTCCCGGGCGGGCGTGGGAGGAGGGAGGCGGCCTCCATGCACTTTATGTGGAGAC
TACTGGCCCCGCCCGTGGCCTCGTGCTCCGCAGGGCGCCCAGCGCCGTCCGGCGGCCCCGCCGCAGACCAGCTGGCGGGT
GTGGAGACCAGGCTCCTGACCCCGCCATGCATGCAGCGCCACCTGGAAGCCGCGCGGCCGCTTTGGTTTTTTGTTTGGTT
GGTTCCATTTTCTTTTTTTCTTTTTTTTTTTAAGAAAAAATAAAAGGTGGATTTGAGCTGTGGCTGTGAGGGGTGTTTGG
GAGCTGCTGGGTGGCAGGGGGGCTGTGGGGTCGGGCTCACGTCGCGGCCGCCTTTGCGCTCTCGGGTCACCCTGCTTTGG
CGGCCCGGCCGGAGGGCAGGACCCTCACCTCTCCCCCAAGGCCACTGCGCTCTTGGGACCCCAGAGAAAACCCGGAGCAA
GCAGGAGTGTGCGGTCAATATTTATATCATCCAGAAAAGAAAAACACGAGAAACGCCATCGCGGGATGGTGCAGACGCGG
CGGGGACTCGGAGGGTGCCGTGCGGGCGAGGCCGCCCAAATTTGGCAATAAATAAAGCTTGGGAAGCTTGGACCTGAAAA
AAAAAA
|
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| |
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|
|
Exon number |
1
|
Length |
1405 nt
|
Location |
Chromosome 19 (NC_000019.9) : 1205797...1207201 (+)
|
Is part of |
STK11, mRNA isoform 1
(NM_000455.4)
|
Sequence |
Show
|
|
GCGTGTCGGGCGCGGAAGGGGGAGGCGGCCCGGGGCGCCCGCGAGTGAGGCGCGGGGCGGCGAAGGGAGCGCGGGTGGCG
GCACTTGCTGCCGCGGCCTTGGATGGGCTGGGCCCCCCTCGCCGCTCCGCCTCCTCCACACGCGCGGCGGCCGCGGCGAG
GGGGACGCGCCGCCCGGGGCCCGGCACCTTCGGGAACCCCCCGGCCCGGAGCCTGCGGCCTGCGCCGCCTCGGCCGCCGG
GAGCCCCGTGGAGCCCCCGCCGCCGCGCCGCCCCGCGGACCGGACGCTGAGGGCACTCGGGGCGGGGCGCGCGCTCGGGC
AGACGTTTGCGGGGAGGGGGGCGCCTGCCGGGCCCCGGCGACCACCTTGGGGGTCGCGGGCCGGCTCGGGGGGCGCCCAG
TGCGGGCCCTCGCGGGCGCCGGGCAGCGACCAGCCCTGAGCGGAGCTGTTGGCCGCGGCGGGAGGCCTCCCGGACGCCCC
CAGCCCCCCGAACGCTCGCCCGGGCCGGCGGGAGTCGGCGCCCCCCGGGAGGTCCGCTCGGTCGTCCGCGGCGGAGCGTT
TGCTCCTGGGACAGGCGGTGGGACCGGGGCGTCGCCGGAGACGCCCCCAGCGAAGTTGGGCTCTCCAGGTGTGGGGGTCC
CGGGGGGTAGCGACGTCGCGGACCCGGCCTGTGGGATGGGCGGCCCGGAGAAGACTGCGCTCGGCCGTGTTCATACTTGT
CCGTGGGCCTGAGGTCCCCGGAGGATGACCTAGCACTGAAAAGCCCCGGCCGGCCTCCCCAGGGTCCCCGAGGACGAAGT
TGACCCTGACCGGGCCGTCTCCCAGTTCTGAGGCCCGGGTCCCACTGGAACTCGCGTCTGAGCCGCCGTCCCGGACCCCC
GGTGCCCGCCGGTCCGCAGACCCTGCACCGGGCTTGGACTCGCAGCCGGGACTGACGTGTAGAACAATCGTTTCTGTTGG
AAGAAGGGTTTTTCCCTTCCTTTTGGGGTTTTTGTTGCCTTTTTTTTTTCTTTTTTCTTTGTAAAATTTTGGAGAAGGGA
AGTCGGAACACAAGGAAGGACCGCTCACCCGCGGACTCAGGGCTGGCGGCGGGACTCCAGGACCCTGGGTCCAGCATGGA
GGTGGTGGACCCGCAGCAGCTGGGCATGTTCACGGAGGGCGAGCTGATGTCGGTGGGTATGGACACGTTCATCCACCGCA
TCGACTCCACCGAGGTCATCTACCAGCCGCGCCGCAAGCGGGCCAAGCTCATCGGCAAGTACCTGATGGGGGACCTGCTG
GGGGAAGGCTCTTACGGCAAGGTGAAGGAGGTGCTGGACTCGGAGACGCTGTGCAGGAGGGCCGTCAAGATCCTCAAGAA
GAAGAAGTTGCGAAGGATCCCCAACGGGGAGGCCAACGTGAAGAA
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Exon number |
3
|
Length |
90 nt
|
Location |
Chromosome 19 (NC_000019.9) : 1219322...1219411 (+)
|
Is part of |
STK11, mRNA isoform 1
(NM_000455.4)
|
Sequence |
Show
|
|
GTATATGGTGATGGAGTACTGCGTGTGTGGCATGCAGGAAATGCTGGACAGCGTGCCGGAGAAGCGTTTCCCAGTGTGCC
AGGCCCACGG
|
|
|
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|
|
|
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|
|
Exon number |
4
|
Length |
133 nt
|
Location |
Chromosome 19 (NC_000019.9) : 1220371...1220503 (+)
|
Is part of |
STK11, mRNA isoform 1
(NM_000455.4)
|
Sequence |
Show
|
|
GTACTTCTGTCAGCTGATTGACGGCCTGGAGTACCTGCATAGCCAGGGCATTGTGCACAAGGACATCAAGCCGGGGAACC
TGCTGCTCACCACCGGTGGCACCCTCAAAATCTCCGACCTGGGCGTGGCCGAG
|
|
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|
Exon number |
5
|
Length |
137 nt
|
Location |
Chromosome 19 (NC_000019.9) : 1220579...1220715 (+)
|
Is part of |
STK11, mRNA isoform 1
(NM_000455.4)
|
Sequence |
Show
|
|
GCACTGCACCCGTTCGCGGCGGACGACACCTGCCGGACCAGCCAGGGCTCCCCGGCTTTCCAGCCGCCCGAGATTGCCAA
CGGCCTGGACACCTTCTCCGGCTTCAAGGTGGACATCTGGTCGGCTGGGGTCACCCT
|
|
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|
Exon number |
6
|
Length |
128 nt
|
Location |
Chromosome 19 (NC_000019.9) : 1221211...1221338 (+)
|
Is part of |
STK11, mRNA isoform 1
(NM_000455.4)
|
Sequence |
Show
|
|
CTACAACATCACCACGGGTCTGTACCCCTTCGAAGGGGACAACATCTACAAGTTGTTTGAGAACATCGGGAAGGGGAGCT
ACGCCATCCCGGGCGACTGTGGCCCCCCGCTCTCTGACCTGCTGAAAG
|
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Exon number |
8
|
Length |
188 nt
|
Location |
Chromosome 19 (NC_000019.9) : 1222983...1223170 (+)
|
Is part of |
STK11, mRNA isoform 1
(NM_000455.4)
|
Sequence |
Show
|
|
CTGGTTCCGGAAGAAACATCCTCCGGCTGAAGCACCAGTGCCCATCCCACCGAGCCCAGACACCAAGGACCGGTGGCGCA
GCATGACTGTGGTGCCGTACTTGGAGGACCTGCACGGCGCGGACGAGGACGAGGACCTCTTCGACATCGAGGATGACATC
ATCTACACTCAGGACTTCACGGTGCCCG
|
|
|
|
|
|
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|
|
|
|
|
|
Exon number |
9
|
Length |
210 nt
|
Location |
Chromosome 19 (NC_000019.9) : 1226452...1226661 (+)
|
Is part of |
STK11, mRNA isoform 1
(NM_000455.4)
|
Sequence |
Show
|
|
GACAGGTCCCAGAAGAGGAGGCCAGTCACAATGGACAGCGCCGGGGCCTCCCCAAGGCCGTGTGTATGAACGGCACAGAG
GCGGCGCAGCTGAGCACCAAATCCAGGGCGGAGGGCCGGGCCCCCAACCCTGCCCGCAAGGCCTGCTCCGCCAGCAGCAA
GATCCGCCGGCTGTCGGCCTGCAAGCAGCAGTGAGGCTGGCCGCCTGCAG
|
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|
|
Exon number |
10
|
Length |
843 nt
|
Location |
Chromosome 19 (NC_000019.9) : 1227591...1228433 (+)
|
Is part of |
STK11, mRNA isoform 1
(NM_000455.4)
|
Sequence |
Show
|
|
CCCGTGTCCAGGAGCCCCGCCAGGTGCCCGCGCCAGGCCCTCAGTCTTCCTGCCGGTTCCGCCCGCCCTCCCGGAGAGGT
GGCCGCCATGCTTCTGTGCCGACCACGCCCCAGGACCTCCGGAGCGCCCTGCAGGGCCGGGCAGGGGGACAGCAGGGACC
GGGCGCAGCCCTCCCCCCTCGGCCGCCCGGCAGTGCACGCGGCTTGTTGACTTCGCAGCCCCGGGCGGAGCCTTCCCGGG
CGGGCGTGGGAGGAGGGAGGCGGCCTCCATGCACTTTATGTGGAGACTACTGGCCCCGCCCGTGGCCTCGTGCTCCGCAG
GGCGCCCAGCGCCGTCCGGCGGCCCCGCCGCAGACCAGCTGGCGGGTGTGGAGACCAGGCTCCTGACCCCGCCATGCATG
CAGCGCCACCTGGAAGCCGCGCGGCCGCTTTGGTTTTTTGTTTGGTTGGTTCCATTTTCTTTTTTTCTTTTTTTTTTTAA
GAAAAAATAAAAGGTGGATTTGAGCTGTGGCTGTGAGGGGTGTTTGGGAGCTGCTGGGTGGCAGGGGGGCTGTGGGGTCG
GGCTCACGTCGCGGCCGCCTTTGCGCTCTCGGGTCACCCTGCTTTGGCGGCCCGGCCGGAGGGCAGGACCCTCACCTCTC
CCCCAAGGCCACTGCGCTCTTGGGACCCCAGAGAAAACCCGGAGCAAGCAGGAGTGTGCGGTCAATATTTATATCATCCA
GAAAAGAAAAACACGAGAAACGCCATCGCGGGATGGTGCAGACGCGGCGGGGACTCGGAGGGTGCCGTGCGGGCGAGGCC
GCCCAAATTTGGCAATAAATAAAGCTTGGGAAGCTTGGACCTG
|
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|
Primary source |
Uniprot : Q15831
|
Name |
Serine/threonine-protein kinase 11
|
Alternative name(s) |
Renal carcinoma antigen NY-REN-19 Serine/threonine-protein kinase LKB1
|
Synonym(s) |
|
Organism |
Homo sapiens
|
Length |
433 aa
|
Protein existence |
---
|
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General annotation (Comments)
|
top
|
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|
Catalytic activity
|
ATP + a protein = ADP + a phosphoprotein.
|
Cofactor
|
Magnesium or Manganese.
|
Disease
|
Defects in STK11 are a cause of Peutz-Jeghers syndrome (PJS) [MIM:175200]. PJS is a rare hereditary disease in which there is predisposition to benign and malignant tumors of many organ systems. PJS is an autosomal dominant disorder characterized by melanocytic macules of the lips, multiple gastrointestinal hamartomatous polyps and an increased risk for various neoplasms, including gastrointestinal cancer.
Defects in STK11 have been associated with testicular tumors [MIM:273300]. It includes germ cell tumor (GCT) or testicular germ cell tumor (TGCT).
|
Enzyme regulation
|
Activated by binding of a complex consisting of CAB39 and STRAD or CAB39 and ALS2CR2.
|
Function
|
Essential role in G1 cell cycle arrest. Phosphorylates and activates members of the AMPK-related subfamily of protein kinases. Tumor suppressor.
|
Ptm
|
Phosphorylated by a cAMP-dependent protein kinase (By similarity).
|
Similarity
|
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. LKB1 subfamily.
Contains 1 protein kinase domain.
|
Subcellular location
|
Nucleus. Cytoplasm. Note=Relocates to the cytoplasm when bound to CAB39 and STRAD or CAB39 and ALS2CR2.
|
Subunit
|
Found in a ternary complex composed of SMAD4, STK11 and STK11IP. Interacts with SMAD4, STK11IP and WDR6.
|
Tissue specificity
|
Ubiquitously expressed. Strongest expression in testis and fetal liver.
|
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|
Biological process
|
protein amino acid phosphorylation [GO:0006468]
cell cycle arrest [GO:0007050]
regulation of fatty acid oxidation [GO:0046320]
|
Cellular component
|
nucleus [GO:0005634]
cytoplasm [GO:0005737]
|
Molecular function
|
magnesium ion binding [GO:0000287]
protein serine/threonine kinase activity [GO:0004674]
ATP binding [GO:0005524]
|
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With
|
Uniprot accession
|
IntAct
|
CAB39
|
Q9Y376
|
EBI-306838,EBI-306905
|
PARD3
|
Q8TEW0
|
EBI-306838,EBI-81968
|
RPAP3
|
Q9H6T3
|
EBI-306838,EBI-356928
|
HSP90AA1
|
P07900
|
EBI-306838,EBI-296047
|
SMARCC1
|
Q92922
|
EBI-306838,EBI-355653
|
FKBP5
|
Q13451
|
EBI-306838,EBI-306914
|
AP2M1
|
Q96CW1
|
EBI-306838,EBI-297683
|
TNIP2
|
Q8NFZ5
|
EBI-306838,EBI-359372
|
WDR6
|
Q9NNW5
|
EBI-306838,EBI-1568315
|
EIF2B1
|
Q14232
|
EBI-306838,
|
MARK4
|
Q96L34
|
EBI-306838,EBI-302319
|
LIMS1
|
P48059
|
EBI-306838,EBI-306928
|
HSPA1B
|
P08107
|
EBI-306838,EBI-629985
|
SMARCA4
|
P51532
|
EBI-306838,EBI-302489
|
KIF23
|
Q02241
|
EBI-306838,EBI-306852
|
STRADA
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Q7RTN6
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EBI-306838,EBI-1109114
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???
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P84091
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EBI-306838,EBI-297703
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USP11
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P51784
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EBI-306838,EBI-306876
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CDC37
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Q16543
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EBI-306838,EBI-295634
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STRADB
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Q9C0K7
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EBI-306838,EBI-306893
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Alternative product(s)
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top
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Feature key |
Position
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Length
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Description
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Feature identifier
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Region |
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Domain
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49 - 309
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261
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Protein kinase
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Q15831-DOMAIN-49
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Nucleotide binding
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55 - 63
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9
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ATP (By similarity)
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Q15831-NP_BIND-55
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Sites |
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Active site
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176 - 176
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1
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Proton acceptor
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Q15831-ACT_SITE-176
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Binding site
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78 - 78
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1
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ATP (By similarity)
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Q15831-BINDING-78
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Natural variations |
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Natural variant site
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49 - 49
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1
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Y -> D (in melanoma; sporadic malignant; somatic mutation)
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VAR_033138
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Natural variant site
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67 - 67
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1
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L -> P (in PJS)
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VAR_006202
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Natural variant site
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87 - 87
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1
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R -> K (in a metastatic melanoma sample; somatic mutation)
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VAR_041139
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Natural variant site
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135 - 135
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1
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G -> R (in melanoma; sporadic malignant; somatic mutation)
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VAR_033139
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Natural variant site
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162 - 164
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3
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DGL -> NDM (in PJS)
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VAR_007920
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Natural variant site
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163 - 163
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1
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G -> D (in testicular tumors; a tumor with seminoma and teratoma components; associated with severely impaired but detectable kinase activity; somatic mutation)
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VAR_033140
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Natural variant site
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194 - 194
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1
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D -> N (in PJS)
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VAR_007921
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Natural variant site
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194 - 194
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1
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D -> Y (in melanoma; sporadic malignant; somatic mutation)
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VAR_033141
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Natural variant site
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239 - 239
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1
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W -> C (in PJS; late onset suggests reduced penetrance)
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VAR_033142
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Natural variant site
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247 - 247
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1
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Missing (in PJS)
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VAR_006203
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Natural variant site
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297 - 297
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1
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R -> K (in PJS)
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VAR_007922
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Natural variant site
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303 - 306
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4
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IRQH -> N (in PJS)
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VAR_033143
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Natural variant site
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315 - 315
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1
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P -> S (in PJS; pathogenicity uncertain)
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VAR_033144
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Amino acid modifications |
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Modified residue
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31 - 31
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1
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Phosphoserine
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Q15831-MOD_RES-31
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Modified residue
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336 - 336
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1
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Phosphothreonine; by autocatalysis
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Q15831-MOD_RES-336
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Modified residue
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363 - 363
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1
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Phosphothreonine; by autocatalysis
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Q15831-MOD_RES-363
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Modified residue
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428 - 428
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1
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Phosphoserine; by PKA (Potential)
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Q15831-MOD_RES-428
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Experimental info |
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Mutagenesis
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176 - 176
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1
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D->Y: Loss of kinase activity
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Q15831-MUTAGEN-176
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Mutagenesis
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194 - 194
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1
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D->A: Loss of kinase activity
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Q15831-MUTAGEN-194
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1 |
MEVVDPQQLG |
MFTEGELMSV |
GMDTFIHRID |
STEVIYQPRR |
KRAKLIGKYL |
MGDLLGEGSY |
GKVKEVLDSE |
TLCRRAVKIL |
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81 |
KKKKLRRIPN |
GEANVKKEIQ |
LLRRLRHKNV |
IQLVDVLYNE |
EKQKMYMVME |
YCVCGMQEML |
DSVPEKRFPV |
CQAHGYFCQL |
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161 |
IDGLEYLHSQ |
GIVHKDIKPG |
NLLLTTGGTL |
KISDLGVAEA |
LHPFAADDTC |
RTSQGSPAFQ |
PPEIANGLDT |
FSGFKVDIWS |
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241 |
AGVTLYNITT |
GLYPFEGDNI |
YKLFENIGKG |
SYAIPGDCGP |
PLSDLLKGML |
EYEPAKRFSI |
RQIRQHSWFR |
KKHPPAEAPV |
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321 |
PIPPSPDTKD |
RWRSMTVVPY |
LEDLHGADED |
EDLFDIEDDI |
IYTQDFTVPG |
QVPEEEASHN |
GQRRGLPKAV |
CMNGTEAAQL |
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401 |
STKSRAEGRA |
PNPARKACSA |
SSKIRRLSAC |
KQQ |
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>sp|Q15831|STK11_human Serine/threonine-protein kinase 11
MEVVDPQQLGMFTEGELMSVGMDTFIHRIDSTEVIYQPRRKRAKLIGKYLMGDLLGEGSYGKVKEVLDSETLCRRAVKIL
KKKKLRRIPNGEANVKKEIQLLRRLRHKNVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSVPEKRFPVCQAHGYFCQL
IDGLEYLHSQGIVHKDIKPGNLLLTTGGTLKISDLGVAEALHPFAADDTCRTSQGSPAFQPPEIANGLDTFSGFKVDIWS
AGVTLYNITTGLYPFEGDNIYKLFENIGKGSYAIPGDCGPPLSDLLKGMLEYEPAKRFSIRQIRQHSWFRKKHPPAEAPV
PIPPSPDTKDRWRSMTVVPYLEDLHGADEDEDLFDIEDDIIYTQDFTVPGQVPEEEASHNGQRRGLPKAVCMNGTEAAQL
STKSRAEGRAPNPARKACSASSKIRRLSACKQQ
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