(TP53) tumor protein p53 [Homo sapiens]
Gene
Transcript(s)
Exon(s)
Protein(s)
Gene
 Accession  8717
 Official symbol  TP53
 Official name  tumor protein p53
 Gene type  gene with protein product
 Organism  Homo sapiens
 Location  Chromosome 17 (NC_000017.10) :  7571719...7590862  (-)
 Map  17p13.1
 Length  19144  nt
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Alternative name(s) and Synynom(s) top
Synonyms TRP53; FLJ92943; p53; LFS1
Alternative name(s) transformation-related protein 53; p53 transformation suppressor; p53 antigen; phosphoprotein p53; p53 tumor suppressor; Li-Fraumeni syndrome
External Links top
Ensembl ENSG00000141510
Entrez 7157
HGNC 11998
HPRD 01859
Comment top
Summary This gene encodes tumor protein p53, which responds to diverse cellular stresses to regulate target genes that induce cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. p53 protein is expressed at low level in normal cells and at a high level in a variety of transformed cell lines, where it's believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing transcription activation, DNA-binding, and oligomerization domains. It is postulated to bind to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor. Mutants of p53 that frequently occur in a number of different human cancers fail to bind the consensus DNA binding site, and hence cause the loss of tumor suppressor activity. Alterations of this gene occur not only as somatic mutations in human malignancies, but also as germline mutations in some cancer-prone families with Li-Fraumeni syndrome. Multiple p53 variants due to alternative promoters and multiple alternative splicing have been found. These variants encode distinct isoforms, which can regulate p53 transcriptional activity. [provided by RefSeq].
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Related Articles in PubMed
Genomic Context top
Go to ensembl   www.ensembl.org
Sequence top
FASTA
ATTGGGGTTT TCCCCTCCCA TGTGCTCAAG ACTGGCGCTA AAAGTTTTGA GCTTCTCAAA AGTCTAGAGC CACCGTCCAG
81  GGAGCAGGTA GCTGCTGGGC TCCGGGGACA CTTTGCGTTC GGGCTGGGAG CGTGCTTTCC ACGACGGTGA CACGCTTCCC
161  TGGATTGGGT AAGCTCCTGA CTGAACTTGA TGAGTCCTCT CTGAGTCACG GGCTCTCGGC TCCGTGTATT TTCAGCTCGG
241  GAAAATCGCT GGGGCTGGGG GTGGGGCAGT GGGGACTTAG CGAGTTTGGG GGTGAGTGGG ATGGAAGCTT GGCTAGAGGG
321  ATCATCATAG GAGTTGCATT GTTGGGAGAC CTGGGTGTAG ATGATGGGGA TGTTAGGACC ATCCGAACTC AAAGTTGAAC
401  GCCTAGGCAG AGGAGTGGAG CTTTGGGGAA CCTTGAGCCG GCCTAAAGCG TACTTCTTTG CACATCCACC CGGTGCTGGG
481  CGTAGGGAAT CCCTGAAATA AAAGATGCAC AAAGCATTGA GGTCTGAGAC TTTTGGATCT CGAAACATTG AGAACTCATA
561  GCTGTATATT TTAGAGCCCA TGGCATCCTA GTGAAAACTG GGGCTCCATT CCGAAATGAT CATTTGGGGG TGATCCGGGG
641  AGCCCAAGCT GCTAAGGTCC CACAACTTCC GGACCTTTGT CCTTCCTGGA GCGATCTTTC CAGGCAGCCC CCGGCTCCGC
721  TAGATGGAGA AAATCCAATT GAAGGCTGTC AGTCGTGGAA GTGAGAAGTG CTAAACCAGG GGTTTGCCCG CCAGGCCGAG
801  GAGGACCGTC GCAATCTGAG AGGCCCGGCA GCCCTGTTAT TGTTTGGCTC CACATTTACA TTTCTGCCTC TTGCAGCAGC
881  ATTTCCGGTT TCTTTTTGCC GGAGCAGCTC ACTATTCACC CGATGAGAGG GGAGGAGAGA GAGAGAAAAT GTCCTTTAGG
961  CCGGTTCCTC TTACTTGGCA GAGGGAGGCT GCTATTCTCC GCCTGCATTT CTTTTTCTGG ATTACTTAGT TATGGCCTTT
1041  GCAAAGGCAG GGGTATTTGT TTTGATGCAA ACCTCAATCC CTCCCCTTCT TTGAATGGTG TGCCCCACCC CGCGGGTCGC
1121  CTGCAACCTA GGCGGACGCT ACCATGGCGT GAGACAGGGA GGGAAAGAAG TGTGCAGAAG GCAAGCCCGG AGGTATTTTC
1201  AAGAATGAGT ATATCTCATC TTCCCGGAGG AAAAAAAAAA AGAATGGGTA CGTCTGAGAA TCAAATTTTG AAAGAGTGCA
1281  ATGATGGGTC GTTTGATAAT TTGTCGGAAA AACAATCTAC CTGTTATCTA GCTTTGGGCT AGGCCATTCC AGTTCCAGAC
1361  GCAGGCTGAA CGTCGTGAAG CGGAAGGGGC GGGCCCGCAG GCGTCCGTGT GGTCCTCCGT GCAGCCCTCC GGCCCGAGCC
1441  GGTTCTTCCT GGTAGGAGGC GGAACTCGAA TTCATTTCTC CCGCTGCCCC ATCTCTTAGC TCGCGGTTGT TTCATTCCGC
1521  AGTTTCTTCC CATGCACCTG CCGCGTACCG GCCACTTTGT GCCGTACTTA CGTCATCTTT TTCCTAAATC GAGGTGGCAT
1601  TTACACACAG CGCCAGTGCA CACAGCAAGT GCACAGGAAG ATGAGTTTTG GCCCCTAACC GCTCCGTGAT GCCTACCAAG
1681  TCACAGACCC TTTTCATCGT CCCAGAAACG TTTCATCACG TCTCTTCCCA GTCGATTCCC GACCCCACCT TTATTTTGAT
1761  CTCCATAACC ATTTTGCCTG TTGGAGAACT TCATATAGAA TGGAATCAGG CTGGGCGCTG TGGCTCACGC CTGCACTTTG
1841  GGAGGCCGAG GCGGGCGGAT TACTTGAGGA TAGGAGTTCC AGACCAGCGT GGCCAACGTG GTGAATCCCC GTCTCTACTA
1921  AAAAATACAA AAATTAGCTG GGCGTGGTGG GTGCCTGTAA TCCCAGCTAT TCGGGAGGGT GAGGCAGGAG AATCGCTTGA
2001  ACCCGGGAGG CAGAGGTTGC AGTGAGCCAA GATCGTGCCA CTACACTCCA GCCTGGGCGA CAAGAACGAA ACTCCGTCTC
2081  AAAAAAAAGG GGGGAATCAT ACATTATGTG CTCATTTTTG TCGGGCTTCT GTCCTTCAAT GTACTGTCTG ACATTCGTTC
2161  ATGTTGTATA TATCAGTATT TTGCTCCTTT TCATTTAGTA TAGTCCATCG ATTGTATATC CGTCCTTTTG ATGGCCTTTT
2241  GAGTTGTTTC CCATTTGCGG TTATGAAATA AAGCTGCTAT AAACATTCTT GTACAATTCT TTTTGTGATC ATATGTTTTC
2321  GTGTTTCTTG GAGAAATACT TAGGAGGGGA ATTGCGAGTT TGGAAGTAAA AAGTAGCTGT ATTTTGAACT TTTTCAGAAG
2401  CTCTGAGTTT TCCAGAGCGG TTGTACCATT TTACACTCCA ACTAGCAAGG TATGGGAGTT ATTATGGTTG TGCCACAGCC
2481  TTCCGGACAT TAGGTATTGT CAGTCTTTCT AATGTGGTAT ATCCTTGTGG TTGTAATTTA CAGTTCTCTA TTGACTAAGG
2561  ATGTTCAGCA TTTTTTCATG TGCCTATTGG CCATTCGTAT TTTGTTTGTA AAGTAGCTCT TCGAGTCTTT TACCTGTTAT
2641  TTTGGTTTTT TGTTTGTTTT TATTGTTCAG TTGTGGGACT GCTTTATACA TTCTGGATAC AAGTCCTTTA TCAGATCCAT
2721  GTGTCGTGAA TGTTTTCTTC TGATCTGTTG CTTGCCTATT TGTTTGCTTT ACAGAGTTTA CAGTATCTTA AGAGGAGTGG
2801  ATTTATCTTT TTTATGTTCA GTATTTGCCT TGTCCTGTTT AGGACATCTT TTTTTTTTTT TTTAACCCCA GGGTCATGAA
2881  GATATTATCT TACATTTTCT TTTAGGACCT TTATGGTTGT AAGTTTTACA GTAAGGTCCT TGAGCCATTA ATTAATTCTT
2961  AAAATTAATT GTTTATGGTG TGAGGTGTAG GAGTCAGTCT CTGGTATCTT TCCTGTATGG AAATCCAGTT ATTCTGTCTC
3041  CACTTGTTGA AATAGGCTTC CTTTCTCTAC TGAATGCTTT TAATTTTAAT TATTTTACAG TTGGAGTATA GGGCTACCAT
3121  TTTAGTGCTA TTTTCTTTTT TTCTTTGTTA ATTTTTGAGA CAGGGACTCA CACTGTTGCC CAGGCTAGAG TACAATGGCA
3201  CAATCAAGGC TTACTGCAGC CTCGAACCCC TGGGCTCAAG CAGTCCTCTA GCAGCCTCAC GAGTAGCTGG GATTACTCCA
3281  CCACACCCAG CTAACTATTT TATTTTTTTG TATTGACAGG ATCTCACTAT GTTGCCCAGG CTGGTCTCAA ACTGCTGGCC
3361  TCAAGCTTTC ATCCCATCTC GGCCTCCCAA AGTGCTGGGA TTACAGGTGT GAGCCACCAT GCCTGACCTC TTAGTGCTAT
3441  TTTCTATTTA TCTCCTCTGT TCTCTGCTCT CTTTAAACGT TGGAGGAAGA AACAGTACCC ATCTTACACA AACTCTTCAG
3521  AAAACAGAGG AACAGACTGG GCGCGGTGGC TCATACCTGT AATCTCAGCA CTTTGGTACG CTGAGGCAGG GGATCATTTG
3601  AGGTCGGGAG TTCGAGACCA GCCTGGCCAA CACGGCGAAA CCCCATCTCT ACTAAAAATA CAAAAAGTAG CTAGGCGTGG
3681  TGACACATAC CTGTAATGCC AGTTACTCAG GAGGCTGAGG CACAAGAATC CCTTGAACCT GGGAAGCGGA GGTTGCAGTG
3761  AGCCGAGATT GCGCCACTGC ACTCCAGCCT GGGCAACAGA GTGAGACCCT GTCTCAGAAA AAAAAAGAAA GAAAGAAAAA
3841  ATAGAGGAAT ATTTCCCAAC TTGTTTTCGA AGCCAGCATA ATCCTGGTAC CAAAACCAAA CAAGGACATT ATAAGAAAAG
3921  AAAATATAGA CCAATATTCC TGTTAGCATA GACATGCAAC AGCTAACCAA TTTTAGCAAA CCAAACCTGG TAATATAGAA
4001  AAAAGGATAA ATAGGCCAGT CGCGGTGGCT CACGCCTGTA ATCCCAGCAC TTTGGGAGGC TGAGGCAGGC AGATCACTTG
4081  AGGTCAGGAG TTTGAGACCA GCCTGACCAA CATGGTGAAA CCCCGTTTCT AATAAAAATA CAAAAATCAG GCTGGGCACG
4161  GTGGCTCACG CCTGTAATCC CAGCACTTTG GGAGGCCGAG GTGGGCAGAT CACGAGGTCA GGAGTTCAAG ACCAGCCTGA
4241  CCAATGTGGT GAAACGCCAT CTCTACTAAA AATACAAAAA TCAGCCGGTG TGGTGGCACC TGCCTGTAAT CCCAGCTACT
4321  CAGGAGGCTG AGGCAGAATT GCTTGAACCC GGGAGGCAGA GGTTGCAGTG AGCCAAGATC GTGCCACTGC ACTCCAGCCT
4401  GGGCGACAGA GCAAGACTTC ATCTCAAAAA AAAAAAAAAA TTAGCTGGGC ATGGTGGTGG GCACCTGAAA TCCCAGCTAC
4481  TCGGGAGTCT GAGGCAGGAG AATCGCTTGA ACCCAGGAGG CAGAAGTTGC ACTGAGCTGG GATCACACCA TTGCACTCCA
4561  GCCTGGGCAA CAGAGTGAGA CTCCATCTCA AAAAAAGAAA AAGAAAAAGG ATAAATACAT TCTAACCAAA TAATGTTTAT
4641  CTCATGATTG TAGCTGATTC AACATTCAAA AATTGGCCTG GTGCAGTAGC TCAGGCCTGT AATCCCAACA TTTTAGGAGG
4721  CTGAGGCAGG AAGATCTCTT GAGCCCAGGA TTTCAAGACC AGCCTGGGCA ACATAGTCAG ACTGGTCTTT ACTGGGGGGA
4801  AAAAAATCAG TCTGTGTAAT TCACCACATT AACAAAGGGA AACATAAAAA CCCTATGATC ATTTCAACAG ATGTAGCAAA
4881  AGCAGTTAAT GATATTCAAC ACATATGCAT GATTACAAAC CAACCAACCT CCTAGCAAAC TAGGGAAAGG AAACTTAACC
4961  TAGTTTGATA ACAGGGCGTC CACAGTCGGA GTTCCACTAG CAGCATACAT AATGGTAGAA AACTCAGTGC TGCCGGGCGC
5041  GGTGGCTCAC GCCTGTAATG CCAGCACTTT GGGAGGCCTA GGCGGGCGGA TCACGAGGTC AGGAGATCGA GACTGTCCTG
5121  ACTAGCATGC TGAAACCCCG TCTCTACTAA AAATACAAAA ACAAAAAATT AGCCGGGCAT GGTGGCGGGC GCCTATAGTC
5201  CCAGCTACTC GGGAGGCTGA GGCGAGAGAA TGGCGTGAAC CCGGGAGGCG GAGCTTGCAG AGCCTAGATC GTGCCACTGC
5281  ACTCCAGCCT GGGTGACAGA GTGAGACTTC GTCTCAAAAA AAAAAAAAAA AAAAAAAGAA AAGAAAACTC AACGCTTTTT
5361  CCTCTAAGAT CAGGAACTAG AAAAGGATTT GACTCTCACA ACGTTGATAC CATACTGGAG GTTTTAACCA GGCAAGAAAA
5441  AGAAATAATG AGGGCCGGGT GCGGTGGCTC AGGCCTGTAA TCCCAGCACT TTGGGAAGCC GAGACGGGTG GATCACGAGG
5521  TCAGGAGATC GAGACCATCC TGGCTAACAC GGTGAAACCC TGTCTCTACT AAATATACAA AAAATTAGCC GGGCGTAGTG
5601  GCGGGCGCCT GTAGTCCCAG CTACTCGGGA GGCTGAGGCA GGAGAATGGC GTGAACTCAG GGGGCGGAGC TTGCAGTGAG
5681  CTGAGATCGA GCCACTGCAC TCCAGCCTGG GCGACAGAGC AAGACTGTGT CTCAAAAAAA AAAAAAGAAA AAGAAATAAT
5761  GATTAGTGGC CCGATGTCTC ACGCCTATAA TCCCAGCACT TTGGGAGGCC GAGGTGGGCA GATCACCTGA GGTCTGGAGT
5841  TGGAGACCAG CCTGACAAAG ATGGTGAAAC CTCGTCTCTA TTAAAATATT AAAAAAATAG CCAGGCGTTG GCCGGGTACA
5921  GTGGCTCATG CCTGTAATCC CAGCACTTTG GGAGGCCGAG GTGGGTGGAT CACCTGAGGT CAGGAGTTCA ACACCAGCCT
6001  GGCCAACATG GTGAAACCCC ATCTCTACTA AAAATACAAA AATTAGCCGG GCGTAGTGGC GGGCGCCTGT AATCCCAGCT
6081  ACTTGGGAGG CTTAGGCAGG AGAATCGCTT GAACCTGGGA GGCGGAGGTT GTAGTGAGCC GAGATTGCAC CATTGCACTC
6161  CAGCCTGGGT GACAAAAGCA AAAACTCCGT CTCAAAAAAA AAAGAATTAG CCAGGGGTAG TGGTGAACGC CTGTAGTCCC
6241  AGCTACTCAG GAGGCAGAGG CAGGAGAATC ACTTGAACCC AGGAGGCAGA GGTTGCAGTG AGCCGAGATT GTCCCATTGC
6321  ACTCCAGCCT AGGCGACAAG AGCAAAATTC CATGTCAAAA AAAAAAAAAA AAAAGGAAAG AAAAAAAATA ACGATTAGAA
6401  AGGAAGAAAT AAAACACATT CACAGCCAGT ATGATTCTAT ACATACATGT CCTAATGGGG CCAGGCGTGG TGGCTCATGC
6481  CTGTAATCCT AGCACTTTTA GGAGGCTGAG GCAGGTGGCT TCCCTGGGAC CAGCCTGGCC AACATGGTGA AACCCCAACT
6561  CTAATAAAAA TACAAAAAAT CAGCCAGGCG TGGTGACGGG CACCTCTAAT CCCAGCTACT CAGGAGGCTG AGGCAGGAGA
6641  ATTGCTTGGA CCTGGGAGGC AGAGGTTGCA GTGAGCCGAG ATCGCGCTAT TGCACTCCAG CCTGGGCAAC AAGAGTGAAA
6721  CTCCGGCAGG GTGTGGTGGC TTACGCCTGT AATCCCAGCA CTTCGGGAGG CTGAGGCAGG CCGATCACCT GAGGTCAGGA
6801  GTTTGAGACC AACCTAACAT GGTGAAACCC CGTCTCTACT AAAAATACAA GAATTAGCTG GGTGTAGTGG TGGGCGCCTG
6881  TAATCCCAGC TACTTGGGAG GCTGAGACAG AAGAATTGCT TGAACCCAGG AGGTGGAGGT TGCAGTGAGC TGAGATCATG
6961  CCATTGCACA CCACGCCGGG CAACAGAGCG AGATTCCGTC TCAAAAAAAA AAAAAAAGAG TGAAACTCTA TCTCAAAAAA
7041  AAAAAAAAGT CCTAATGGAA AATCCATAAA AAGCTACCAA AACTAATAAA TAAATATAGC AGGGTTGCAG GTTACAGGGC
7121  AATATAGTTA TCCCTCTATC TGTAGGGGCT TGGTTCTGGG ACTCCTCACA CACCAAACCC ACAGATGTCT AAGTCCCATA
7201  TATAAGACGG TATAGTATTT GGATTTAACC TACACATATC CTCCCATATA GTTTAAATTA TCTCTAGATT ACTTACATTA
7281  CCCCCATACA ATGAAAATGC TAATGTACAT GCAAGTATGT ATGTAAGTAC TTGTACTATA TTGTTTAGGG AATCACTGGA
7361  CATATAGGCC TTCAAGACTG ATACCAGCAG CCACTGTTAA GATTCTGGTC AGGCCTGCCC CTGTTTGGGG TCTCAGTTGA
7441  TCTCATTGCC TTCCCACCCA GCCAAGGGCA CCTGCATTTC TCTTGGCTCC CTGGCCATTT GGAAGGCCTA GTTCAGCCTG
7521  GCACATTTGT ATCCTGGCCC ACTGATGCTG GTACCCCTGG GAAGGTCCTG CTCTGAAAAA CACGGAGATT TTAGTTGCTA
7601  CTGAAGATTT GAGAGATAAA GACAGGGAGA CCTGTCTGTA GACCTGTGTC CCTCCAAGTG GGATTGAGAC TTTGGGCCCC
7681  CCATTTCAGG ACAGCACCTC CTGGCCTGTT GACTGAATAG ATCCCTGAAG GAGGTGTACT TGCATTAATG GAGTGGGGGT
7761  GGGAGCAGTA CCACAGATCC GCACTAACAA TCACACAGTT CTCTCTAGAA TAATAATATA GAACAAGTGA AATAGAACAA
7841  TTGCAGAAAG AGCTAACCTT TGTTGAGCTC TTACTGTGTG CCCAGCACTT TCCTCAACTC TACATTTCCC ATAATACACA
7921  GAGTACTAGG TAGGCCAGGC TTGGTGGCTC ACGCCTGTAA TCCCAGCACT TTAGGAGGCC AAGGGGGGTG GATCACCTGA
8001  GGTCGGGAGT TCAAGACCAG CCTGACCAAC ATGGTGAAAC CCCGTCTCTA CTAGAAGTAC AAAATTAGCC AGGTGTGGTG
8081  GCACATGCTT GTAGTCCTAG CTACTCAGCA GGCTGAGGCA GGAGAATCAT TTGAATCCGG GAGGAGGTTG CAGTAAGCGG
8161  AGATAGTGCC ACTGTACTCC AGCCTGGGCA ATAAGAGCTG AGACTCCGTC TCAAAATAAA ATAAAATAAA ATAAAATAAA
8241  ATAAAATAAA ATAAAAAAAG AAAAGAGCCT GCCATTAAAG GAGCTGTTTG GTAGGGGATG TTTTGTCAGT GCAAACAACA
8321  GAAAAGTGGG CTGGGCACAG TGGTTCATGC CTGTAATCCC AGCACTTTGG GAGGCCAAGG CGGGCGGATC ACCTGAAGTT
8401  GGGAGTTCAA GACCAGCCTG ACCAATATGG AGAAACCCCG TCTCTACTAA AAATACAAAA TTAGCCGGGC GCAGTGGCGC
8481  ATGCCTGTAA TCCCAGCTAC TCGGGAGGCT GAGGCAGGAG AATCGCTTGA ACCTGGGAGG CAGAGGTTGC GGTGAGCCGA
8561  GATCGCACCA TTGCACTCCA GCCTGGACGA GAGCAAAACT CTGTCTCAAA AAAAAAAAAA AACAGAAAAG TGTAACAAAC
8641  ACTTACAGTA GGCATGTTTC TTAGCAAATC TGATGACAAA TTTGGCATAA AGAAAGAGAG CATCCCTGAA AAAAAAAAAA
8721  AGAAAAAGAA AGAGAGCATC CTGCCTGGGC AACATAGTGA AACCCTGCCT CTACAAAAAA ACTCAAAAAT TGGCCGGGTG
8801  CAGTGGCTCA CACCTGTAAT CCCAGCACTT TGGGAGTCGG AGGCGGGAGG ATCACCTGAG GTCAGGAGTT CGAAACCAGC
8881  CTGGCCAACA TGGCAAAACC CCATCTCTAC TAAAAATACA AAAAATTAAT CAGGCGCATT GGTGGGCGCC TGTAATCCCA
8961  GCTACTCAGG AAGTTGAGGC AAGAGGATCG CTTGAATCTG GGAGGTGGAG GTTACAGTGA GTCGAGATCA CACCACTGCA
9041  CTCTAGCCTG GGTGACAGGG CGAGACTCCG TCTCCAAAAA AAAAAAGAAA AAGAAAAAGA CTAAAAAATT AGCCAGGCAG
9121  GCCTCTGTGG TCCCAGCTAC TTGGGAGGCT GAGGCAGGAG AATCACTGAG CCCAGGAGTC CGAGGCTGTA GTGAGCCATG
9201  ATTGCACCAC TGTACCCTAG CTTGGGCAAC AAAGCAAGAC CCTGCCTCAA AAGAAAAAAG AAAGAAAGAA AGAACATGGC
9281  GGGCCAGGCA CAGTGGCTCA CACCTGTAAT CCCAGCGCTT TGAGAGGCCG AGGCAGGTGG ATCACAAGGT CAGGAGTTCC
9361  ACACCAGCCT GGCCAACATG GTGAAACCCT GTCTCTACTA AAAATACAAA AAATCAGCCA GGCATGGTGG CAGGGGCCTG
9441  TAATCCCAGC TACTCGGGAG GCTGAGGCAG GAGAATTGCT TGAAACCAGA AGGCAGAGGT TGCAGTGAGC CTAGACTGCA
9521  CCACTGCACT CCAGCCTGGG CGAAAAGAGC CAAACTCCAT CTCAAAAAAC AAACAAAAAA ACAAAACAAA AGAAAACATG
9601  GCAAAGCCTT TGAAAGCTTG TCTGGGAGAA GGTGCGATGA TAGTTGCATA ACTTCGTGCA AGATGCTGGT CCACACAGGG
9681  GCTGCCCCTT GCTCTTTCTC GCTCTCTTAA CCTCTCATAT AACAGGCTTG TGTGTTATTC ACATTTATTG AGCCCAAGCA
9761  GGTGCAAGGC ATTGTGATCT AATACTTTGG TCAGCAAGAC AACAAGATAG ATCACTGCCC TGCCCTTAGG AAGTGTATAT
9841  GCTATTAGAG GAAACAGATA AAATAAACAA GGAAAAGTAT CAGACAATGT AAGTGCTATG AGAATGCAAA TGAGGTGATG
9921  TGAATTAAAA TAGGATGACT TAAAGTCTGC ACGGGAAGGA GCCTACCCCC ATGTTCCTGG CTAGCCAAGG AACCACCAGT
10001  TGATTAGCAG AGAAGGGCAG CCAGTCTAGC TAGAGCTTTT GGGGAAGAGG GAGTGGTTGT TAAGAGATGA GATTAAAGAA
10081  GCCGAGACGG GCCATTCGTG AGGGGTTTGT AATGCAGGGC TGAGGAGTGT CCGAAGAGAA TGGGCAGGTG AGCGGTGAGA
10161  CAGTTGTTCT TCCAGAAGCT TTGCAGTGAA AGGAATCAAA GAAATGGAGC CGTGTATCAG GTGGGGAAGG GTGGGGGCCA
10241  AGGGGGTGTC CTTCCCCATA CAGAGATTGC AGGCTGAGAA TGACTATATC CTTGTTAACA GGAGGTGGGA GCAGGGCACG
10321  GTAGCTCACA CCTGTAATCT TGGCACTTTA GGAGGCTGAG GCGGGCCGAT CACCTGAAGT AAGGAGTTCG AGACCAGCCT
10401  GGCCAACATG CAAAGCCCTG TCTCTACTAA AAATACAAAA ATTAGCTGGG TGTGGTGGTA CTCGCCTGTA ATCCCAGCTA
10481  CTCGGGAGAC TGAGGCAGGA GAATGGCTTG AACCCGGAAG GTAGAGGTTG CAGTGAGCTG AGATCATGCC ACTGTGCTCC
10561  AGCCTAGGTG ACAGAGAGAG ACTCCATCTC AAAAAAAAAA AAAAAATACA GGAAGGGAGT TGGGAATAGG GTGCACATTT
10641  AGGAAGTCTT GGGGATTTAG TGGTGGGAAG GTTGGAAGTC CCTCTCTGAT TGTCTTTTCC TCAAAGAAGT GCATGGCTGG
10721  TGAGGGGTGG GGCAGGAGTG CTTGGGTTGT GGTGAAACAT TGGAAGAGAG AATGTGAAGC AGCCATTCTT TTCCTGCTCC
10801  ACAGGAAGCC GAGCTGTCTC AGACACTGGC ATGGTGTTGG GGGAGGGGGT TCCTTCTCTG CAGGCCCAGG TGACCCAGGG
10881  TTGGAAGTGT CTCATGCTGG ATCCCCACTT TTCCTCTTGC AGCAGCCAGA CTGCCTTCCG GGTCACTGCC ATGGAGGAGC
10961  CGCAGTCAGA TCCTAGCGTC GAGCCCCCTC TGAGTCAGGA AACATTTTCA GACCTATGGA AACTGTGAGT GGATCCATTG
11041  GAAGGGCAGG CCCACCACCC CCACCCCAAC CCCAGCCCCC TAGCAGAGAC CTGTGGGAAG CGAAAATTCC ATGGGACTGA
11121  CTTTCTGCTC TTGTCTTTCA GACTTCCTGA AAACAACGTT CTGGTAAGGA CAAGGGTTGG GCTGGGGACC TGGAGGGCTG
11201  GGGACCTGGA GGGCTGGGGG GCTGGGGGGC TGAGGACCTG GTCCTCTGAC TGCTCTTTTC ACCCATCTAC AGTCCCCCTT
11281  GCCGTCCCAA GCAATGGATG ATTTGATGCT GTCCCCGGAC GATATTGAAC AATGGTTCAC TGAAGACCCA GGTCCAGATG
11361  AAGCTCCCAG AATGCCAGAG GCTGCTCCCC CCGTGGCCCC TGCACCAGCA GCTCCTACAC CGGCGGCCCC TGCACCAGCC
11441  CCCTCCTGGC CCCTGTCATC TTCTGTCCCT TCCCAGAAAA CCTACCAGGG CAGCTACGGT TTCCGTCTGG GCTTCTTGCA
11521  TTCTGGGACA GCCAAGTCTG TGACTTGCAC GGTCAGTTGC CCTGAGGGGC TGGCTTCCAT GAGACTTCAA TGCCTGGCCG
11601  TATCCCCCTG CATTTCTTTT GTTTGGAACT TTGGGATTCC TCTTCACCCT TTGGCTTCCT GTCAGTGTTT TTTTATAGTT
11681  TACCCACTTA ATGTGTGATC TCTGACTCCT GTCCCAAAGT TGAATATTCC CCCCTTGAAT TTGGGCTTTT ATCCATCCCA
11761  TCACACCCTC AGCATCTCTC CTGGGGATGC AGAACTTTTC TTTTTCTTCA TCCACGTGTA TTCCTTGGCT TTTGAAAATA
11841  AGCTCCTGAC CAGGCTTGGT GGCTCACACC TGCAATCCCA GCACTCTCAA AGAGGCCAAG GCAGGCAGAT CACCTGAGCC
11921  CAGGAGTTCA AGACCAGCCT GGGTAACATG ATGAAACCTC GTCTCTACAA AAAAATACAA AAAATTAGCC AGGCATGGTG
12001  GTGCACACCT ATAGTCCCAG CCACTTAGGA GGCTGAGGTG GGAAGATCAC TTGAGGCCAG GAGATGGAGG CTGCAGTGAG
12081  CTGTGATCAC ACCACTGTGC TCCAGCCTGA GTGACAGAGC AAGACCCTAT CTCAAAAAAA AAAAAAAAAA AGAAAAGCTC
12161  CTGAGGTGTA GACGCCAACT CTCTCTAGCT CGCTAGTGGG TTGCAGGAGG TGCTTACGCA TGTTTGTTTC TTTGCTGCCG
12241  TCTTCCAGTT GCTTTATCTG TTCACTTGTG CCCTGACTTT CAACTCTGTC TCCTTCCTCT TCCTACAGTA CTCCCCTGCC
12321  CTCAACAAGA TGTTTTGCCA ACTGGCCAAG ACCTGCCCTG TGCAGCTGTG GGTTGATTCC ACACCCCCGC CCGGCACCCG
12401  CGTCCGCGCC ATGGCCATCT ACAAGCAGTC ACAGCACATG ACGGAGGTTG TGAGGCGCTG CCCCCACCAT GAGCGCTGCT
12481  CAGATAGCGA TGGTGAGCAG CTGGGGCTGG AGAGACGACA GGGCTGGTTG CCCAGGGTCC CCAGGCCTCT GATTCCTCAC
12561  TGATTGCTCT TAGGTCTGGC CCCTCCTCAG CATCTTATCC GAGTGGAAGG AAATTTGCGT GTGGAGTATT TGGATGACAG
12641  AAACACTTTT CGACATAGTG TGGTGGTGCC CTATGAGCCG CCTGAGGTCT GGTTTGCAAC TGGGGTCTCT GGGAGGAGGG
12721  GTTAAGGGTG GTTGTCAGTG GCCCTCCAGG TGAGCAGTAG GGGGGCTTTC TCCTGCTGCT TATTTGACCT CCCTATAACC
12801  CCATGAGATG TGCAAAGTAA ATGGGTTTAA CTATTGCACA GTTGAAAAAA CTGAAGCTTA CAGAGGCTAA GGGCCTCCCC
12881  TGCTTGGCTG GGCGCAGTGG CTCATGCCTG TAATCCCAGC ACTTTGGGAG GCCAAGGCAG GCGGATCACG AGGTTGGGAG
12961  ATCGAGACCA TCCTGGCTAA CGGTGAAACC CCGTCTCTAC TGAAAAATAC AAAAAAAAAT TAGCCGGGCG TGGTGCTGGG
13041  CACCTGTAGT CCCAGCTACT CGGGAGGCTG AGGAAGGAGA ATGGCGTGAA CCTGGGCGGT GGAGCTTGCA GTGAGCTGAG
13121  ATCACGCCAC TGCACTCCAG CCTGGGCGAC AGAGCGAGAT TCCATCTCAA AAAAAAAAAA AAAAGGCCTC CCCTGCTTGC
13201  CACAGGTCTC CCCAAGGCGC ACTGGCCTCA TCTTGGGCCT GTGTTATCTC CTAGGTTGGC TCTGACTGTA CCACCATCCA
13281  CTACAACTAC ATGTGTAACA GTTCCTGCAT GGGCGGCATG AACCGGAGGC CCATCCTCAC CATCATCACA CTGGAAGACT
13361  CCAGGTCAGG AGCCACTTGC CACCCTGCAC ACTGGCCTGC TGTGCCCCAG CCTCTGCTTG CCTCTGACCC CTGGGCCCAC
13441  CTCTTACCGA TTTCTTCCAT ACTACTACCC ATCCACCTCT CATCACATCC CCGGCGGGGA ATCTCCTTAC TGCTCCCACT
13521  CAGTTTTCTT TTCTCTGGCT TTGGGACCTC TTAACCTGTG GCTTCTCCTC CACCTACCTG GAGCTGGAGC TTAGGCTCCA
13601  GAAAGGACAA GGGTGGTTGG GAGTAGATGG AGCCTGGTTT TTTAAATGGG ACAGGTAGGA CCTGATTTCC TTACTGCCTC
13681  TTGCTTCTCT TTTCCTATCC TGAGTAGTGG TAATCTACTG GGACGGAACA GCTTTGAGGT GCGTGTTTGT GCCTGTCCTG
13761  GGAGAGACCG GCGCACAGAG GAAGAGAATC TCCGCAAGAA AGGGGAGCCT CACCACGAGC TGCCCCCAGG GAGCACTAAG
13841  CGAGGTAAGC AAGCAGGACA AGAAGCGGTG GAGGAGACCA AGGGTGCAGT TATGCCTCAG ATTCACTTTT ATCACCTTTC
13921  CTTGCCTCTT TCCTAGCACT GCCCAACAAC ACCAGCTCCT CTCCCCAGCC AAAGAAGAAA CCACTGGATG GAGAATATTT
14001  CACCCTTCAG GTACTAAGTC TTGGGACCTC TTATCAAGTG GAAAGTTTCC AGTCTAACAC TCAAAATGCC GTTTTCTTCT
14081  TGACTGTTTT ACCTGCAATT GGGGCATTTG CCATCAGGGG GCAGTGATGC CTCAAAGACA ATGGCTCCTG GTTGTAGCTA
14161  ACTAACTTCA GAACACCAAC TTATACCATA ATATATATTT TAAAGGACCA GACCAGCTTT CAAAAAGAAA ATTGTTAAAG
14241  AGAGCATGAA AATGGTTCTA TGACTTTGCC TGATACAGAT GCTACTTGAC TTACGATGGT GTTACTTCCT GATAAACTCG
14321  TCGTAAGTTG AAAATATTGT AAGTTGAAAA TGGATTTAAT ACACCTAATC TAAGGAACAT CATAGCTTAG CCTAGCCTGC
14401  TTTTTTTTTT TTTTTTTTTG GAGACAGAGT CTCACTCTGT CACCCAGGCT GGAGTGCAGT GGCGGGATCT CGGCTCACTG
14481  CAACCTCCGC CTTCTGGGTT CAAGCGATTC TCCTGCCTCA GCCCACTGAG TAGCTGGGAT TACAGGCACC TGCCCCGACG
14561  CCCAGCTAAT TTTTTGTTAT TTATTTATTT TTTTTTTTAG TAGAGATGAG GTTTCACCAT GTTGGCCAGG CTAGTCTCGA
14641  ACTCCTGACC TTGTGATCTG CCTGCCTTGG CCTCCCAAAG TGCTGGGATT ACAGGCGTGA GCCACCGCAC CCGGCCTGCC
14721  TAGCCTACTT TTATTTTATT TTTAATGGAG ACAGCATCTT GCTCTGTTGC CCAGGCTGGA TTACAGTGAT GTGATCATAG
14801  CTCATTATAC CCTCCTGGGC TCAAGCAATC CCCCTAACTC TGCCTCCCCA GTAGCTAGGA CCACAGGCAT ACACCACCAT
14881  ACCCAGCTAA TTTTTAAAAT TTTTTGTAGA TAGATAGAGT CTCACTATGT TGCCCAGGCT GGTCTCTAGC CTACTTTTTT
14961  GAGACAAGGT CTTGCTCTGT CACCCAGGCT GGATAGAGTG CAGTAGTGCA GTCACAGCTC ACTGCAGCCT CCACCTCCCA
15041  GGCTCCATCC ATCCTCCCAG CTCAGCCTCC CAAGTTGCTT CAACTACAGG CCTGCACCAC CATGCCTGGC TAATTTTTAT
15121  TTATTTATTT TTATTTTATT TTATTTTATT TTTTTGAGAC TCAGTCTCAC TCTGTCGCCC AGGCTGGAGT GCAGTGGCAT
15201  GATCTCGGCT CACTGCAACC TCTGCCTCCT GGGTTCAAGT GATTCTCCTG CCTCAGCCTC CCGAATAGCT AGGACTACAA
15281  GCGCCTGCTA CCACGCCCAG CTAATTTTTG TATTTTTAGT AGAGACAGGG TTTCACCATG TTGGCCAGGC TGGTCTCGAA
15361  CTTCTGACCA TGTGATCCGC CCGCCTCGGC CTCCCAAAGT GCTGGGATTA CAGGTGTGAG CCACCACGCC CGGCTAATTT
15441  TTATTTATTT ATTTAAAGAC AGAGTCTCAC TCTGTCACTC AGGCTAGAGT GCAGTGGCAC CATCTCAGCT CACTGCAGCC
15521  TTGACCTCCC TGGGCTCCGG TGATTTCACC CTCCCAAGTA GCTAGGACTA CAGGCACATG CCACGACACC CAGCTAATTT
15601  TTTATTTTCT GTGAAGTCAA GGTCTTGCTA CGTTGCCCAT GCTGGTATCA AACCCCTGGG CTCAATCAAT CCTTCCACCT
15681  CAGCCTCCCC AAGTATTGGG GTTACAGGCA TGAGCTACCA CACTCAGCCC TAGCCTACTT GAAACGTGTT CAGAGCATTT
15761  AAGTTACCCT ACAGTTGGGC AAAGTCATCT AACACAAAGC CCTTTTTATA GTAATAAAAT GTTGTATATC TCATGTGATT
15841  TATTGAATAT TGTTACTGAA AGTGAGAAAC AGCATGGTTG CATGAAAGGA GGCACAGTCG AGCCAGGCAC AGCCTGGGCG
15921  CAGAGCGAGA CTCAAAAAAA GAAAAGGCCA GGCGCACTGG CTCACGCCTG TAATCCCAGC ATTTCGGGAG GCTGAGGCGG
16001  GTGGATCACC TGAGGTCAGG AGTTCAAGAC CAGCCTAGCC AACATGGTGA AACCCCGTCT CTACTAAAAT ACAAAAATTA
16081  ACCGGGCGTG ATGGCAGGTG CCTGTAATCC CAGCTACTTG GGAGGCTGAG GCAGGAGAAT CGCTTGAACC AGGAGGCGGA
16161  GGTTGCAGGG AGCCAAGATG GCGCCACTGC ACTCCAGCCT GGGCGATAGA GTGAGACTCC GTCTCAGAAA AAAAAGAAAA
16241  GAAACGAGGC ACAGTCGCAT GCACATGTAG TCCCAGTTAC TTGAGAGGCT AAGGCAGGAG GATCTCTTGA GCCCAAGAGT
16321  TTGAGTCCAG CCTGAACAAC ATAGCAAGAC ATCATCTCTA AAATTTAAAA AAGGGCCGGG CACAGTGGCT CACACCTGTA
16401  ATCCCAGCAC TTTGGGAGGT GGAGGTGGGT AGATCACCTG ACGTCAGGAG TTGGAAACCA GCCTGGCTAA CATGGTGAAG
16481  CCCCATCTCT ACTAAAAACA CAAAAATTAG CCAGGTGTGG TAGCACACGC CTGTAGTCCC AGCTACTCGG GAGGCTGAGG
16561  CACAAGAATC ACTTGAACCC CAGAGGCGGA GATTGCAATC AGCCAAGATT GCACCATTGC ACTCCCGCCT GGGCAACAGA
16641  GTGAGACCCC ATCTCAAAAT AAATAAATAA ATATTTTTAA AAGTCAGCTG TATAGGTACT TGAAGTGCAG TTTCTACTAA
16721  ATGCATGTTG CTTTTGTACC GTCATAAAGT CAAACAATTG TAACTTGAAC CATCTTTTAA CTCAGGTACT GTGTATATAC
16801  TTACTTCTCC CCCTCCTCTG TTGCTGCAGA TCCGTGGGCG TGAGCGCTTC GAGATGTTCC GAGAGCTGAA TGAGGCCTTG
16881  GAACTCAAGG ATGCCCAGGC TGGGAAGGAG CCAGGGGGGA GCAGGGCTCA CTCCAGGTGA GTGACCTCAG CCCCTTCCTG
16961  GCCCTACTCC CCTGCCTTCC TAGGTTGGAA AGCCATAGGA TTCCATTCTC ATCCTGCCTT CATGGTCAAA GGCAGCTGAC
17041  CCCATCTCAT TGGGTCCCAG CCCTGCACAG ACATTTTTTT AGTCTTCCTC CGGTTGAATC CTATAACCAC ATTCTTGCCT
17121  CAGTGTATCC ACAGAACATC CAAACCCAGG GACGAGTGTG GATACTTCTT TGCCATTCTC CGCAACTCCC AGCCCAGAGC
17201  TGGAGGGTCT CAAGGAGGGG CCTAATAATT GTGTAATACT GAATACAGCC AGAGTTTCAG GTCATATACT CAGCCCTGCC
17281  ATGCACCGGC AGGTCCTAGG TGACCCCCGT CAAACTCAGT TTCCTTATAT ATAAAATGGG GTAAGGGGGC CGGGCGCAGT
17361  GGCTCACGAA TCCCACACTC TGGGAGGCCA AGGCGAGTGG ATCACCTGAG GTCGGGAGTT TGAGCCCAGC CTGACCAACA
17441  TGGAGAAACC CCATCTCTAC TAAAAATACA AAAGTAGCCG GGCGTGGTGA TGCATGCCTG TAATCCCAGC TACCTACTCG
17521  GGAGGCTGAG GCAGGAGAAT CGCTTGAACC CGGGAGGCAG AGGTTGCGGT GAGCTGAGAT CTCACCATTA CACTCCAGCC
17601  TGGGCAACAA GAGTGAAACT CCGTCTCAAA AAAGATAAAT AAAGTAAAAT GGGGTAAGGG AAGATTACGA GACTAATACA
17681  CACTAATACT CTGAGGTGCT CAGTAAACAT ATTTGCATGG GGTGTGGCCA CCATCTTGAT TTGAATTCCC GTTGTCCCAG
17761  CCTTAGGCCC TTCAAAGCAT TGGTCAGGGA AAAGGGGCAC AGACCCTCTC ACTCATGTGA TGTCATCTCT CCTCCCTGCT
17841  TCTGTCTCCT ACAGCCACCT GAAGTCCAAA AAGGGTCAGT CTACCTCCCG CCATAAAAAA CTCATGTTCA AGACAGAAGG
17921  GCCTGACTCA GACTGACATT CTCCACTTCT TGTTCCCCAC TGACAGCCTC CCACCCCCAT CTCTCCCTCC CCTGCCATTT
18001  TGGGTTTTGG GTCTTTGAAC CCTTGCTTGC AATAGGTGTG CGTCAGAAGC ACCCAGGACT TCCATTTGCT TTGTCCCGGG
18081  GCTCCACTGA ACAAGTTGGC CTGCACTGGT GTTTTGTTGT GGGGAGGAGG ATGGGGAGTA GGACATACCA GCTTAGATTT
18161  TAAGGTTTTT ACTGTGAGGG ATGTTTGGGA GATGTAAGAA ATGTTCTTGC AGTTAAGGGT TAGTTTACAA TCAGCCACAT
18241  TCTAGGTAGG GGCCCACTTC ACCGTACTAA CCAGGGAAGC TGTCCCTCAC TGTTGAATTT TCTCTAACTT CAAGGCCCAT
18321  ATCTGTGAAA TGCTGGCATT TGCACCTACC TCACAGAGTG CATTGTGAGG GTTAATGAAA TAATGTACAT CTGGCCTTGA
18401  AACCACCTTT TATTACATGG GGTCTAGAAC TTGACCCCCT TGAGGGTGCT TGTTCCCTCT CCCTGTTGGT CGGTGGGTTG
18481  GTAGTTTCTA CAGTTGGGCA GCTGGTTAGG TAGAGGGAGT TGTCAAGTCT CTGCTGGCCC AGCCAAACCC TGTCTGACAA
18561  CCTCTTGGTG AACCTTAGTA CCTAAAAGGA AATCTCACCC CATCCCACAC CCTGGAGGAT TTCATCTCTT GTATATGATG
18641  ATCTGGATCC ACCAAGACTT GTTTTATGCT CAGGGTCAAT TTCTTTTTTC TTTTTTTTTT TTTTTTTTCT TTTTCTTTGA
18721  GACTGGGTCT CGCTTTGTTG CCCAGGCTGG AGTGGAGTGG CGTGATCTTG GCTTACTGCA GCCTTTGCCT CCCCGGCTCG
18801  AGCAGTCCTG CCTCAGCCTC CGGAGTAGCT GGGACCACAG GTTCATGCCA CCATGGCCAG CCAACTTTTG CATGTTTTGT
18881  AGAGATGGGG TCTCACAGTG TTGCCCAGGC TGGTCTCAAA CTCCTGGGCT CAGGCGATCC ACCTGTCTCA GCCTCCCAGA
18961  GTGCTGGGAT TACAATTGTG AGCCACCACG TCCAGCTGGA AGGGTCAACA TCTTTTACAT TCTGCAAGCA CATCTGCATT
19041  TTCACCCCAC CCTTCCCCTC CTTCTCCCTT TTTATATCCC ATTTTTATAT CGATCTCTTA TTTTACAATA AAACTTTGCT
19121  GCCACCTGTG TGTCTGAGGG GTGA
>ref|Gene_ID:7157|TP53|NC_000017.10:7571719...7590862 (-)
ATTGGGGTTTTCCCCTCCCATGTGCTCAAGACTGGCGCTAAAAGTTTTGAGCTTCTCAAAAGTCTAGAGCCACCGTCCAG
GGAGCAGGTAGCTGCTGGGCTCCGGGGACACTTTGCGTTCGGGCTGGGAGCGTGCTTTCCACGACGGTGACACGCTTCCC
TGGATTGGGTAAGCTCCTGACTGAACTTGATGAGTCCTCTCTGAGTCACGGGCTCTCGGCTCCGTGTATTTTCAGCTCGG
GAAAATCGCTGGGGCTGGGGGTGGGGCAGTGGGGACTTAGCGAGTTTGGGGGTGAGTGGGATGGAAGCTTGGCTAGAGGG
ATCATCATAGGAGTTGCATTGTTGGGAGACCTGGGTGTAGATGATGGGGATGTTAGGACCATCCGAACTCAAAGTTGAAC
GCCTAGGCAGAGGAGTGGAGCTTTGGGGAACCTTGAGCCGGCCTAAAGCGTACTTCTTTGCACATCCACCCGGTGCTGGG
CGTAGGGAATCCCTGAAATAAAAGATGCACAAAGCATTGAGGTCTGAGACTTTTGGATCTCGAAACATTGAGAACTCATA
GCTGTATATTTTAGAGCCCATGGCATCCTAGTGAAAACTGGGGCTCCATTCCGAAATGATCATTTGGGGGTGATCCGGGG
AGCCCAAGCTGCTAAGGTCCCACAACTTCCGGACCTTTGTCCTTCCTGGAGCGATCTTTCCAGGCAGCCCCCGGCTCCGC
TAGATGGAGAAAATCCAATTGAAGGCTGTCAGTCGTGGAAGTGAGAAGTGCTAAACCAGGGGTTTGCCCGCCAGGCCGAG
GAGGACCGTCGCAATCTGAGAGGCCCGGCAGCCCTGTTATTGTTTGGCTCCACATTTACATTTCTGCCTCTTGCAGCAGC
ATTTCCGGTTTCTTTTTGCCGGAGCAGCTCACTATTCACCCGATGAGAGGGGAGGAGAGAGAGAGAAAATGTCCTTTAGG
CCGGTTCCTCTTACTTGGCAGAGGGAGGCTGCTATTCTCCGCCTGCATTTCTTTTTCTGGATTACTTAGTTATGGCCTTT
GCAAAGGCAGGGGTATTTGTTTTGATGCAAACCTCAATCCCTCCCCTTCTTTGAATGGTGTGCCCCACCCCGCGGGTCGC
CTGCAACCTAGGCGGACGCTACCATGGCGTGAGACAGGGAGGGAAAGAAGTGTGCAGAAGGCAAGCCCGGAGGTATTTTC
AAGAATGAGTATATCTCATCTTCCCGGAGGAAAAAAAAAAAGAATGGGTACGTCTGAGAATCAAATTTTGAAAGAGTGCA
ATGATGGGTCGTTTGATAATTTGTCGGAAAAACAATCTACCTGTTATCTAGCTTTGGGCTAGGCCATTCCAGTTCCAGAC
GCAGGCTGAACGTCGTGAAGCGGAAGGGGCGGGCCCGCAGGCGTCCGTGTGGTCCTCCGTGCAGCCCTCCGGCCCGAGCC
GGTTCTTCCTGGTAGGAGGCGGAACTCGAATTCATTTCTCCCGCTGCCCCATCTCTTAGCTCGCGGTTGTTTCATTCCGC
AGTTTCTTCCCATGCACCTGCCGCGTACCGGCCACTTTGTGCCGTACTTACGTCATCTTTTTCCTAAATCGAGGTGGCAT
TTACACACAGCGCCAGTGCACACAGCAAGTGCACAGGAAGATGAGTTTTGGCCCCTAACCGCTCCGTGATGCCTACCAAG
TCACAGACCCTTTTCATCGTCCCAGAAACGTTTCATCACGTCTCTTCCCAGTCGATTCCCGACCCCACCTTTATTTTGAT
CTCCATAACCATTTTGCCTGTTGGAGAACTTCATATAGAATGGAATCAGGCTGGGCGCTGTGGCTCACGCCTGCACTTTG
GGAGGCCGAGGCGGGCGGATTACTTGAGGATAGGAGTTCCAGACCAGCGTGGCCAACGTGGTGAATCCCCGTCTCTACTA
AAAAATACAAAAATTAGCTGGGCGTGGTGGGTGCCTGTAATCCCAGCTATTCGGGAGGGTGAGGCAGGAGAATCGCTTGA
ACCCGGGAGGCAGAGGTTGCAGTGAGCCAAGATCGTGCCACTACACTCCAGCCTGGGCGACAAGAACGAAACTCCGTCTC
AAAAAAAAGGGGGGAATCATACATTATGTGCTCATTTTTGTCGGGCTTCTGTCCTTCAATGTACTGTCTGACATTCGTTC
ATGTTGTATATATCAGTATTTTGCTCCTTTTCATTTAGTATAGTCCATCGATTGTATATCCGTCCTTTTGATGGCCTTTT
GAGTTGTTTCCCATTTGCGGTTATGAAATAAAGCTGCTATAAACATTCTTGTACAATTCTTTTTGTGATCATATGTTTTC
GTGTTTCTTGGAGAAATACTTAGGAGGGGAATTGCGAGTTTGGAAGTAAAAAGTAGCTGTATTTTGAACTTTTTCAGAAG
CTCTGAGTTTTCCAGAGCGGTTGTACCATTTTACACTCCAACTAGCAAGGTATGGGAGTTATTATGGTTGTGCCACAGCC
TTCCGGACATTAGGTATTGTCAGTCTTTCTAATGTGGTATATCCTTGTGGTTGTAATTTACAGTTCTCTATTGACTAAGG
ATGTTCAGCATTTTTTCATGTGCCTATTGGCCATTCGTATTTTGTTTGTAAAGTAGCTCTTCGAGTCTTTTACCTGTTAT
TTTGGTTTTTTGTTTGTTTTTATTGTTCAGTTGTGGGACTGCTTTATACATTCTGGATACAAGTCCTTTATCAGATCCAT
GTGTCGTGAATGTTTTCTTCTGATCTGTTGCTTGCCTATTTGTTTGCTTTACAGAGTTTACAGTATCTTAAGAGGAGTGG
ATTTATCTTTTTTATGTTCAGTATTTGCCTTGTCCTGTTTAGGACATCTTTTTTTTTTTTTTTAACCCCAGGGTCATGAA
GATATTATCTTACATTTTCTTTTAGGACCTTTATGGTTGTAAGTTTTACAGTAAGGTCCTTGAGCCATTAATTAATTCTT
AAAATTAATTGTTTATGGTGTGAGGTGTAGGAGTCAGTCTCTGGTATCTTTCCTGTATGGAAATCCAGTTATTCTGTCTC
CACTTGTTGAAATAGGCTTCCTTTCTCTACTGAATGCTTTTAATTTTAATTATTTTACAGTTGGAGTATAGGGCTACCAT
TTTAGTGCTATTTTCTTTTTTTCTTTGTTAATTTTTGAGACAGGGACTCACACTGTTGCCCAGGCTAGAGTACAATGGCA
CAATCAAGGCTTACTGCAGCCTCGAACCCCTGGGCTCAAGCAGTCCTCTAGCAGCCTCACGAGTAGCTGGGATTACTCCA
CCACACCCAGCTAACTATTTTATTTTTTTGTATTGACAGGATCTCACTATGTTGCCCAGGCTGGTCTCAAACTGCTGGCC
TCAAGCTTTCATCCCATCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCATGCCTGACCTCTTAGTGCTAT
TTTCTATTTATCTCCTCTGTTCTCTGCTCTCTTTAAACGTTGGAGGAAGAAACAGTACCCATCTTACACAAACTCTTCAG
AAAACAGAGGAACAGACTGGGCGCGGTGGCTCATACCTGTAATCTCAGCACTTTGGTACGCTGAGGCAGGGGATCATTTG
AGGTCGGGAGTTCGAGACCAGCCTGGCCAACACGGCGAAACCCCATCTCTACTAAAAATACAAAAAGTAGCTAGGCGTGG
TGACACATACCTGTAATGCCAGTTACTCAGGAGGCTGAGGCACAAGAATCCCTTGAACCTGGGAAGCGGAGGTTGCAGTG
AGCCGAGATTGCGCCACTGCACTCCAGCCTGGGCAACAGAGTGAGACCCTGTCTCAGAAAAAAAAAGAAAGAAAGAAAAA
ATAGAGGAATATTTCCCAACTTGTTTTCGAAGCCAGCATAATCCTGGTACCAAAACCAAACAAGGACATTATAAGAAAAG
AAAATATAGACCAATATTCCTGTTAGCATAGACATGCAACAGCTAACCAATTTTAGCAAACCAAACCTGGTAATATAGAA
AAAAGGATAAATAGGCCAGTCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGCAGATCACTTG
AGGTCAGGAGTTTGAGACCAGCCTGACCAACATGGTGAAACCCCGTTTCTAATAAAAATACAAAAATCAGGCTGGGCACG
GTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCAGATCACGAGGTCAGGAGTTCAAGACCAGCCTGA
CCAATGTGGTGAAACGCCATCTCTACTAAAAATACAAAAATCAGCCGGTGTGGTGGCACCTGCCTGTAATCCCAGCTACT
CAGGAGGCTGAGGCAGAATTGCTTGAACCCGGGAGGCAGAGGTTGCAGTGAGCCAAGATCGTGCCACTGCACTCCAGCCT
GGGCGACAGAGCAAGACTTCATCTCAAAAAAAAAAAAAAATTAGCTGGGCATGGTGGTGGGCACCTGAAATCCCAGCTAC
TCGGGAGTCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGCAGAAGTTGCACTGAGCTGGGATCACACCATTGCACTCCA
GCCTGGGCAACAGAGTGAGACTCCATCTCAAAAAAAGAAAAAGAAAAAGGATAAATACATTCTAACCAAATAATGTTTAT
CTCATGATTGTAGCTGATTCAACATTCAAAAATTGGCCTGGTGCAGTAGCTCAGGCCTGTAATCCCAACATTTTAGGAGG
CTGAGGCAGGAAGATCTCTTGAGCCCAGGATTTCAAGACCAGCCTGGGCAACATAGTCAGACTGGTCTTTACTGGGGGGA
AAAAAATCAGTCTGTGTAATTCACCACATTAACAAAGGGAAACATAAAAACCCTATGATCATTTCAACAGATGTAGCAAA
AGCAGTTAATGATATTCAACACATATGCATGATTACAAACCAACCAACCTCCTAGCAAACTAGGGAAAGGAAACTTAACC
TAGTTTGATAACAGGGCGTCCACAGTCGGAGTTCCACTAGCAGCATACATAATGGTAGAAAACTCAGTGCTGCCGGGCGC
GGTGGCTCACGCCTGTAATGCCAGCACTTTGGGAGGCCTAGGCGGGCGGATCACGAGGTCAGGAGATCGAGACTGTCCTG
ACTAGCATGCTGAAACCCCGTCTCTACTAAAAATACAAAAACAAAAAATTAGCCGGGCATGGTGGCGGGCGCCTATAGTC
CCAGCTACTCGGGAGGCTGAGGCGAGAGAATGGCGTGAACCCGGGAGGCGGAGCTTGCAGAGCCTAGATCGTGCCACTGC
ACTCCAGCCTGGGTGACAGAGTGAGACTTCGTCTCAAAAAAAAAAAAAAAAAAAAAAGAAAAGAAAACTCAACGCTTTTT
CCTCTAAGATCAGGAACTAGAAAAGGATTTGACTCTCACAACGTTGATACCATACTGGAGGTTTTAACCAGGCAAGAAAA
AGAAATAATGAGGGCCGGGTGCGGTGGCTCAGGCCTGTAATCCCAGCACTTTGGGAAGCCGAGACGGGTGGATCACGAGG
TCAGGAGATCGAGACCATCCTGGCTAACACGGTGAAACCCTGTCTCTACTAAATATACAAAAAATTAGCCGGGCGTAGTG
GCGGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACTCAGGGGGCGGAGCTTGCAGTGAG
CTGAGATCGAGCCACTGCACTCCAGCCTGGGCGACAGAGCAAGACTGTGTCTCAAAAAAAAAAAAAGAAAAAGAAATAAT
GATTAGTGGCCCGATGTCTCACGCCTATAATCCCAGCACTTTGGGAGGCCGAGGTGGGCAGATCACCTGAGGTCTGGAGT
TGGAGACCAGCCTGACAAAGATGGTGAAACCTCGTCTCTATTAAAATATTAAAAAAATAGCCAGGCGTTGGCCGGGTACA
GTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGTGGATCACCTGAGGTCAGGAGTTCAACACCAGCCT
GGCCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCGGGCGTAGTGGCGGGCGCCTGTAATCCCAGCT
ACTTGGGAGGCTTAGGCAGGAGAATCGCTTGAACCTGGGAGGCGGAGGTTGTAGTGAGCCGAGATTGCACCATTGCACTC
CAGCCTGGGTGACAAAAGCAAAAACTCCGTCTCAAAAAAAAAAGAATTAGCCAGGGGTAGTGGTGAACGCCTGTAGTCCC
AGCTACTCAGGAGGCAGAGGCAGGAGAATCACTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCCGAGATTGTCCCATTGC
ACTCCAGCCTAGGCGACAAGAGCAAAATTCCATGTCAAAAAAAAAAAAAAAAAAGGAAAGAAAAAAAATAACGATTAGAA
AGGAAGAAATAAAACACATTCACAGCCAGTATGATTCTATACATACATGTCCTAATGGGGCCAGGCGTGGTGGCTCATGC
CTGTAATCCTAGCACTTTTAGGAGGCTGAGGCAGGTGGCTTCCCTGGGACCAGCCTGGCCAACATGGTGAAACCCCAACT
CTAATAAAAATACAAAAAATCAGCCAGGCGTGGTGACGGGCACCTCTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGA
ATTGCTTGGACCTGGGAGGCAGAGGTTGCAGTGAGCCGAGATCGCGCTATTGCACTCCAGCCTGGGCAACAAGAGTGAAA
CTCCGGCAGGGTGTGGTGGCTTACGCCTGTAATCCCAGCACTTCGGGAGGCTGAGGCAGGCCGATCACCTGAGGTCAGGA
GTTTGAGACCAACCTAACATGGTGAAACCCCGTCTCTACTAAAAATACAAGAATTAGCTGGGTGTAGTGGTGGGCGCCTG
TAATCCCAGCTACTTGGGAGGCTGAGACAGAAGAATTGCTTGAACCCAGGAGGTGGAGGTTGCAGTGAGCTGAGATCATG
CCATTGCACACCACGCCGGGCAACAGAGCGAGATTCCGTCTCAAAAAAAAAAAAAAAGAGTGAAACTCTATCTCAAAAAA
AAAAAAAAGTCCTAATGGAAAATCCATAAAAAGCTACCAAAACTAATAAATAAATATAGCAGGGTTGCAGGTTACAGGGC
AATATAGTTATCCCTCTATCTGTAGGGGCTTGGTTCTGGGACTCCTCACACACCAAACCCACAGATGTCTAAGTCCCATA
TATAAGACGGTATAGTATTTGGATTTAACCTACACATATCCTCCCATATAGTTTAAATTATCTCTAGATTACTTACATTA
CCCCCATACAATGAAAATGCTAATGTACATGCAAGTATGTATGTAAGTACTTGTACTATATTGTTTAGGGAATCACTGGA
CATATAGGCCTTCAAGACTGATACCAGCAGCCACTGTTAAGATTCTGGTCAGGCCTGCCCCTGTTTGGGGTCTCAGTTGA
TCTCATTGCCTTCCCACCCAGCCAAGGGCACCTGCATTTCTCTTGGCTCCCTGGCCATTTGGAAGGCCTAGTTCAGCCTG
GCACATTTGTATCCTGGCCCACTGATGCTGGTACCCCTGGGAAGGTCCTGCTCTGAAAAACACGGAGATTTTAGTTGCTA
CTGAAGATTTGAGAGATAAAGACAGGGAGACCTGTCTGTAGACCTGTGTCCCTCCAAGTGGGATTGAGACTTTGGGCCCC
CCATTTCAGGACAGCACCTCCTGGCCTGTTGACTGAATAGATCCCTGAAGGAGGTGTACTTGCATTAATGGAGTGGGGGT
GGGAGCAGTACCACAGATCCGCACTAACAATCACACAGTTCTCTCTAGAATAATAATATAGAACAAGTGAAATAGAACAA
TTGCAGAAAGAGCTAACCTTTGTTGAGCTCTTACTGTGTGCCCAGCACTTTCCTCAACTCTACATTTCCCATAATACACA
GAGTACTAGGTAGGCCAGGCTTGGTGGCTCACGCCTGTAATCCCAGCACTTTAGGAGGCCAAGGGGGGTGGATCACCTGA
GGTCGGGAGTTCAAGACCAGCCTGACCAACATGGTGAAACCCCGTCTCTACTAGAAGTACAAAATTAGCCAGGTGTGGTG
GCACATGCTTGTAGTCCTAGCTACTCAGCAGGCTGAGGCAGGAGAATCATTTGAATCCGGGAGGAGGTTGCAGTAAGCGG
AGATAGTGCCACTGTACTCCAGCCTGGGCAATAAGAGCTGAGACTCCGTCTCAAAATAAAATAAAATAAAATAAAATAAA
ATAAAATAAAATAAAAAAAGAAAAGAGCCTGCCATTAAAGGAGCTGTTTGGTAGGGGATGTTTTGTCAGTGCAAACAACA
GAAAAGTGGGCTGGGCACAGTGGTTCATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGCGGATCACCTGAAGTT
GGGAGTTCAAGACCAGCCTGACCAATATGGAGAAACCCCGTCTCTACTAAAAATACAAAATTAGCCGGGCGCAGTGGCGC
ATGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAGGCAGAGGTTGCGGTGAGCCGA
GATCGCACCATTGCACTCCAGCCTGGACGAGAGCAAAACTCTGTCTCAAAAAAAAAAAAAAACAGAAAAGTGTAACAAAC
ACTTACAGTAGGCATGTTTCTTAGCAAATCTGATGACAAATTTGGCATAAAGAAAGAGAGCATCCCTGAAAAAAAAAAAA
AGAAAAAGAAAGAGAGCATCCTGCCTGGGCAACATAGTGAAACCCTGCCTCTACAAAAAAACTCAAAAATTGGCCGGGTG
CAGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGTCGGAGGCGGGAGGATCACCTGAGGTCAGGAGTTCGAAACCAGC
CTGGCCAACATGGCAAAACCCCATCTCTACTAAAAATACAAAAAATTAATCAGGCGCATTGGTGGGCGCCTGTAATCCCA
GCTACTCAGGAAGTTGAGGCAAGAGGATCGCTTGAATCTGGGAGGTGGAGGTTACAGTGAGTCGAGATCACACCACTGCA
CTCTAGCCTGGGTGACAGGGCGAGACTCCGTCTCCAAAAAAAAAAAGAAAAAGAAAAAGACTAAAAAATTAGCCAGGCAG
GCCTCTGTGGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCACTGAGCCCAGGAGTCCGAGGCTGTAGTGAGCCATG
ATTGCACCACTGTACCCTAGCTTGGGCAACAAAGCAAGACCCTGCCTCAAAAGAAAAAAGAAAGAAAGAAAGAACATGGC
GGGCCAGGCACAGTGGCTCACACCTGTAATCCCAGCGCTTTGAGAGGCCGAGGCAGGTGGATCACAAGGTCAGGAGTTCC
ACACCAGCCTGGCCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAAATCAGCCAGGCATGGTGGCAGGGGCCTG
TAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATTGCTTGAAACCAGAAGGCAGAGGTTGCAGTGAGCCTAGACTGCA
CCACTGCACTCCAGCCTGGGCGAAAAGAGCCAAACTCCATCTCAAAAAACAAACAAAAAAACAAAACAAAAGAAAACATG
GCAAAGCCTTTGAAAGCTTGTCTGGGAGAAGGTGCGATGATAGTTGCATAACTTCGTGCAAGATGCTGGTCCACACAGGG
GCTGCCCCTTGCTCTTTCTCGCTCTCTTAACCTCTCATATAACAGGCTTGTGTGTTATTCACATTTATTGAGCCCAAGCA
GGTGCAAGGCATTGTGATCTAATACTTTGGTCAGCAAGACAACAAGATAGATCACTGCCCTGCCCTTAGGAAGTGTATAT
GCTATTAGAGGAAACAGATAAAATAAACAAGGAAAAGTATCAGACAATGTAAGTGCTATGAGAATGCAAATGAGGTGATG
TGAATTAAAATAGGATGACTTAAAGTCTGCACGGGAAGGAGCCTACCCCCATGTTCCTGGCTAGCCAAGGAACCACCAGT
TGATTAGCAGAGAAGGGCAGCCAGTCTAGCTAGAGCTTTTGGGGAAGAGGGAGTGGTTGTTAAGAGATGAGATTAAAGAA
GCCGAGACGGGCCATTCGTGAGGGGTTTGTAATGCAGGGCTGAGGAGTGTCCGAAGAGAATGGGCAGGTGAGCGGTGAGA
CAGTTGTTCTTCCAGAAGCTTTGCAGTGAAAGGAATCAAAGAAATGGAGCCGTGTATCAGGTGGGGAAGGGTGGGGGCCA
AGGGGGTGTCCTTCCCCATACAGAGATTGCAGGCTGAGAATGACTATATCCTTGTTAACAGGAGGTGGGAGCAGGGCACG
GTAGCTCACACCTGTAATCTTGGCACTTTAGGAGGCTGAGGCGGGCCGATCACCTGAAGTAAGGAGTTCGAGACCAGCCT
GGCCAACATGCAAAGCCCTGTCTCTACTAAAAATACAAAAATTAGCTGGGTGTGGTGGTACTCGCCTGTAATCCCAGCTA
CTCGGGAGACTGAGGCAGGAGAATGGCTTGAACCCGGAAGGTAGAGGTTGCAGTGAGCTGAGATCATGCCACTGTGCTCC
AGCCTAGGTGACAGAGAGAGACTCCATCTCAAAAAAAAAAAAAAAATACAGGAAGGGAGTTGGGAATAGGGTGCACATTT
AGGAAGTCTTGGGGATTTAGTGGTGGGAAGGTTGGAAGTCCCTCTCTGATTGTCTTTTCCTCAAAGAAGTGCATGGCTGG
TGAGGGGTGGGGCAGGAGTGCTTGGGTTGTGGTGAAACATTGGAAGAGAGAATGTGAAGCAGCCATTCTTTTCCTGCTCC
ACAGGAAGCCGAGCTGTCTCAGACACTGGCATGGTGTTGGGGGAGGGGGTTCCTTCTCTGCAGGCCCAGGTGACCCAGGG
TTGGAAGTGTCTCATGCTGGATCCCCACTTTTCCTCTTGCAGCAGCCAGACTGCCTTCCGGGTCACTGCCATGGAGGAGC
CGCAGTCAGATCCTAGCGTCGAGCCCCCTCTGAGTCAGGAAACATTTTCAGACCTATGGAAACTGTGAGTGGATCCATTG
GAAGGGCAGGCCCACCACCCCCACCCCAACCCCAGCCCCCTAGCAGAGACCTGTGGGAAGCGAAAATTCCATGGGACTGA
CTTTCTGCTCTTGTCTTTCAGACTTCCTGAAAACAACGTTCTGGTAAGGACAAGGGTTGGGCTGGGGACCTGGAGGGCTG
GGGACCTGGAGGGCTGGGGGGCTGGGGGGCTGAGGACCTGGTCCTCTGACTGCTCTTTTCACCCATCTACAGTCCCCCTT
GCCGTCCCAAGCAATGGATGATTTGATGCTGTCCCCGGACGATATTGAACAATGGTTCACTGAAGACCCAGGTCCAGATG
AAGCTCCCAGAATGCCAGAGGCTGCTCCCCCCGTGGCCCCTGCACCAGCAGCTCCTACACCGGCGGCCCCTGCACCAGCC
CCCTCCTGGCCCCTGTCATCTTCTGTCCCTTCCCAGAAAACCTACCAGGGCAGCTACGGTTTCCGTCTGGGCTTCTTGCA
TTCTGGGACAGCCAAGTCTGTGACTTGCACGGTCAGTTGCCCTGAGGGGCTGGCTTCCATGAGACTTCAATGCCTGGCCG
TATCCCCCTGCATTTCTTTTGTTTGGAACTTTGGGATTCCTCTTCACCCTTTGGCTTCCTGTCAGTGTTTTTTTATAGTT
TACCCACTTAATGTGTGATCTCTGACTCCTGTCCCAAAGTTGAATATTCCCCCCTTGAATTTGGGCTTTTATCCATCCCA
TCACACCCTCAGCATCTCTCCTGGGGATGCAGAACTTTTCTTTTTCTTCATCCACGTGTATTCCTTGGCTTTTGAAAATA
AGCTCCTGACCAGGCTTGGTGGCTCACACCTGCAATCCCAGCACTCTCAAAGAGGCCAAGGCAGGCAGATCACCTGAGCC
CAGGAGTTCAAGACCAGCCTGGGTAACATGATGAAACCTCGTCTCTACAAAAAAATACAAAAAATTAGCCAGGCATGGTG
GTGCACACCTATAGTCCCAGCCACTTAGGAGGCTGAGGTGGGAAGATCACTTGAGGCCAGGAGATGGAGGCTGCAGTGAG
CTGTGATCACACCACTGTGCTCCAGCCTGAGTGACAGAGCAAGACCCTATCTCAAAAAAAAAAAAAAAAAAGAAAAGCTC
CTGAGGTGTAGACGCCAACTCTCTCTAGCTCGCTAGTGGGTTGCAGGAGGTGCTTACGCATGTTTGTTTCTTTGCTGCCG
TCTTCCAGTTGCTTTATCTGTTCACTTGTGCCCTGACTTTCAACTCTGTCTCCTTCCTCTTCCTACAGTACTCCCCTGCC
CTCAACAAGATGTTTTGCCAACTGGCCAAGACCTGCCCTGTGCAGCTGTGGGTTGATTCCACACCCCCGCCCGGCACCCG
CGTCCGCGCCATGGCCATCTACAAGCAGTCACAGCACATGACGGAGGTTGTGAGGCGCTGCCCCCACCATGAGCGCTGCT
CAGATAGCGATGGTGAGCAGCTGGGGCTGGAGAGACGACAGGGCTGGTTGCCCAGGGTCCCCAGGCCTCTGATTCCTCAC
TGATTGCTCTTAGGTCTGGCCCCTCCTCAGCATCTTATCCGAGTGGAAGGAAATTTGCGTGTGGAGTATTTGGATGACAG
AAACACTTTTCGACATAGTGTGGTGGTGCCCTATGAGCCGCCTGAGGTCTGGTTTGCAACTGGGGTCTCTGGGAGGAGGG
GTTAAGGGTGGTTGTCAGTGGCCCTCCAGGTGAGCAGTAGGGGGGCTTTCTCCTGCTGCTTATTTGACCTCCCTATAACC
CCATGAGATGTGCAAAGTAAATGGGTTTAACTATTGCACAGTTGAAAAAACTGAAGCTTACAGAGGCTAAGGGCCTCCCC
TGCTTGGCTGGGCGCAGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAGGCGGATCACGAGGTTGGGAG
ATCGAGACCATCCTGGCTAACGGTGAAACCCCGTCTCTACTGAAAAATACAAAAAAAAATTAGCCGGGCGTGGTGCTGGG
CACCTGTAGTCCCAGCTACTCGGGAGGCTGAGGAAGGAGAATGGCGTGAACCTGGGCGGTGGAGCTTGCAGTGAGCTGAG
ATCACGCCACTGCACTCCAGCCTGGGCGACAGAGCGAGATTCCATCTCAAAAAAAAAAAAAAAAGGCCTCCCCTGCTTGC
CACAGGTCTCCCCAAGGCGCACTGGCCTCATCTTGGGCCTGTGTTATCTCCTAGGTTGGCTCTGACTGTACCACCATCCA
CTACAACTACATGTGTAACAGTTCCTGCATGGGCGGCATGAACCGGAGGCCCATCCTCACCATCATCACACTGGAAGACT
CCAGGTCAGGAGCCACTTGCCACCCTGCACACTGGCCTGCTGTGCCCCAGCCTCTGCTTGCCTCTGACCCCTGGGCCCAC
CTCTTACCGATTTCTTCCATACTACTACCCATCCACCTCTCATCACATCCCCGGCGGGGAATCTCCTTACTGCTCCCACT
CAGTTTTCTTTTCTCTGGCTTTGGGACCTCTTAACCTGTGGCTTCTCCTCCACCTACCTGGAGCTGGAGCTTAGGCTCCA
GAAAGGACAAGGGTGGTTGGGAGTAGATGGAGCCTGGTTTTTTAAATGGGACAGGTAGGACCTGATTTCCTTACTGCCTC
TTGCTTCTCTTTTCCTATCCTGAGTAGTGGTAATCTACTGGGACGGAACAGCTTTGAGGTGCGTGTTTGTGCCTGTCCTG
GGAGAGACCGGCGCACAGAGGAAGAGAATCTCCGCAAGAAAGGGGAGCCTCACCACGAGCTGCCCCCAGGGAGCACTAAG
CGAGGTAAGCAAGCAGGACAAGAAGCGGTGGAGGAGACCAAGGGTGCAGTTATGCCTCAGATTCACTTTTATCACCTTTC
CTTGCCTCTTTCCTAGCACTGCCCAACAACACCAGCTCCTCTCCCCAGCCAAAGAAGAAACCACTGGATGGAGAATATTT
CACCCTTCAGGTACTAAGTCTTGGGACCTCTTATCAAGTGGAAAGTTTCCAGTCTAACACTCAAAATGCCGTTTTCTTCT
TGACTGTTTTACCTGCAATTGGGGCATTTGCCATCAGGGGGCAGTGATGCCTCAAAGACAATGGCTCCTGGTTGTAGCTA
ACTAACTTCAGAACACCAACTTATACCATAATATATATTTTAAAGGACCAGACCAGCTTTCAAAAAGAAAATTGTTAAAG
AGAGCATGAAAATGGTTCTATGACTTTGCCTGATACAGATGCTACTTGACTTACGATGGTGTTACTTCCTGATAAACTCG
TCGTAAGTTGAAAATATTGTAAGTTGAAAATGGATTTAATACACCTAATCTAAGGAACATCATAGCTTAGCCTAGCCTGC
TTTTTTTTTTTTTTTTTTTGGAGACAGAGTCTCACTCTGTCACCCAGGCTGGAGTGCAGTGGCGGGATCTCGGCTCACTG
CAACCTCCGCCTTCTGGGTTCAAGCGATTCTCCTGCCTCAGCCCACTGAGTAGCTGGGATTACAGGCACCTGCCCCGACG
CCCAGCTAATTTTTTGTTATTTATTTATTTTTTTTTTTAGTAGAGATGAGGTTTCACCATGTTGGCCAGGCTAGTCTCGA
ACTCCTGACCTTGTGATCTGCCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCACCCGGCCTGCC
TAGCCTACTTTTATTTTATTTTTAATGGAGACAGCATCTTGCTCTGTTGCCCAGGCTGGATTACAGTGATGTGATCATAG
CTCATTATACCCTCCTGGGCTCAAGCAATCCCCCTAACTCTGCCTCCCCAGTAGCTAGGACCACAGGCATACACCACCAT
ACCCAGCTAATTTTTAAAATTTTTTGTAGATAGATAGAGTCTCACTATGTTGCCCAGGCTGGTCTCTAGCCTACTTTTTT
GAGACAAGGTCTTGCTCTGTCACCCAGGCTGGATAGAGTGCAGTAGTGCAGTCACAGCTCACTGCAGCCTCCACCTCCCA
GGCTCCATCCATCCTCCCAGCTCAGCCTCCCAAGTTGCTTCAACTACAGGCCTGCACCACCATGCCTGGCTAATTTTTAT
TTATTTATTTTTATTTTATTTTATTTTATTTTTTTGAGACTCAGTCTCACTCTGTCGCCCAGGCTGGAGTGCAGTGGCAT
GATCTCGGCTCACTGCAACCTCTGCCTCCTGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCGAATAGCTAGGACTACAA
GCGCCTGCTACCACGCCCAGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAA
CTTCTGACCATGTGATCCGCCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCACGCCCGGCTAATTT
TTATTTATTTATTTAAAGACAGAGTCTCACTCTGTCACTCAGGCTAGAGTGCAGTGGCACCATCTCAGCTCACTGCAGCC
TTGACCTCCCTGGGCTCCGGTGATTTCACCCTCCCAAGTAGCTAGGACTACAGGCACATGCCACGACACCCAGCTAATTT
TTTATTTTCTGTGAAGTCAAGGTCTTGCTACGTTGCCCATGCTGGTATCAAACCCCTGGGCTCAATCAATCCTTCCACCT
CAGCCTCCCCAAGTATTGGGGTTACAGGCATGAGCTACCACACTCAGCCCTAGCCTACTTGAAACGTGTTCAGAGCATTT
AAGTTACCCTACAGTTGGGCAAAGTCATCTAACACAAAGCCCTTTTTATAGTAATAAAATGTTGTATATCTCATGTGATT
TATTGAATATTGTTACTGAAAGTGAGAAACAGCATGGTTGCATGAAAGGAGGCACAGTCGAGCCAGGCACAGCCTGGGCG
CAGAGCGAGACTCAAAAAAAGAAAAGGCCAGGCGCACTGGCTCACGCCTGTAATCCCAGCATTTCGGGAGGCTGAGGCGG
GTGGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTAGCCAACATGGTGAAACCCCGTCTCTACTAAAATACAAAAATTA
ACCGGGCGTGATGGCAGGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCGCTTGAACCAGGAGGCGGA
GGTTGCAGGGAGCCAAGATGGCGCCACTGCACTCCAGCCTGGGCGATAGAGTGAGACTCCGTCTCAGAAAAAAAAGAAAA
GAAACGAGGCACAGTCGCATGCACATGTAGTCCCAGTTACTTGAGAGGCTAAGGCAGGAGGATCTCTTGAGCCCAAGAGT
TTGAGTCCAGCCTGAACAACATAGCAAGACATCATCTCTAAAATTTAAAAAAGGGCCGGGCACAGTGGCTCACACCTGTA
ATCCCAGCACTTTGGGAGGTGGAGGTGGGTAGATCACCTGACGTCAGGAGTTGGAAACCAGCCTGGCTAACATGGTGAAG
CCCCATCTCTACTAAAAACACAAAAATTAGCCAGGTGTGGTAGCACACGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGG
CACAAGAATCACTTGAACCCCAGAGGCGGAGATTGCAATCAGCCAAGATTGCACCATTGCACTCCCGCCTGGGCAACAGA
GTGAGACCCCATCTCAAAATAAATAAATAAATATTTTTAAAAGTCAGCTGTATAGGTACTTGAAGTGCAGTTTCTACTAA
ATGCATGTTGCTTTTGTACCGTCATAAAGTCAAACAATTGTAACTTGAACCATCTTTTAACTCAGGTACTGTGTATATAC
TTACTTCTCCCCCTCCTCTGTTGCTGCAGATCCGTGGGCGTGAGCGCTTCGAGATGTTCCGAGAGCTGAATGAGGCCTTG
GAACTCAAGGATGCCCAGGCTGGGAAGGAGCCAGGGGGGAGCAGGGCTCACTCCAGGTGAGTGACCTCAGCCCCTTCCTG
GCCCTACTCCCCTGCCTTCCTAGGTTGGAAAGCCATAGGATTCCATTCTCATCCTGCCTTCATGGTCAAAGGCAGCTGAC
CCCATCTCATTGGGTCCCAGCCCTGCACAGACATTTTTTTAGTCTTCCTCCGGTTGAATCCTATAACCACATTCTTGCCT
CAGTGTATCCACAGAACATCCAAACCCAGGGACGAGTGTGGATACTTCTTTGCCATTCTCCGCAACTCCCAGCCCAGAGC
TGGAGGGTCTCAAGGAGGGGCCTAATAATTGTGTAATACTGAATACAGCCAGAGTTTCAGGTCATATACTCAGCCCTGCC
ATGCACCGGCAGGTCCTAGGTGACCCCCGTCAAACTCAGTTTCCTTATATATAAAATGGGGTAAGGGGGCCGGGCGCAGT
GGCTCACGAATCCCACACTCTGGGAGGCCAAGGCGAGTGGATCACCTGAGGTCGGGAGTTTGAGCCCAGCCTGACCAACA
TGGAGAAACCCCATCTCTACTAAAAATACAAAAGTAGCCGGGCGTGGTGATGCATGCCTGTAATCCCAGCTACCTACTCG
GGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAGGCAGAGGTTGCGGTGAGCTGAGATCTCACCATTACACTCCAGCC
TGGGCAACAAGAGTGAAACTCCGTCTCAAAAAAGATAAATAAAGTAAAATGGGGTAAGGGAAGATTACGAGACTAATACA
CACTAATACTCTGAGGTGCTCAGTAAACATATTTGCATGGGGTGTGGCCACCATCTTGATTTGAATTCCCGTTGTCCCAG
CCTTAGGCCCTTCAAAGCATTGGTCAGGGAAAAGGGGCACAGACCCTCTCACTCATGTGATGTCATCTCTCCTCCCTGCT
TCTGTCTCCTACAGCCACCTGAAGTCCAAAAAGGGTCAGTCTACCTCCCGCCATAAAAAACTCATGTTCAAGACAGAAGG
GCCTGACTCAGACTGACATTCTCCACTTCTTGTTCCCCACTGACAGCCTCCCACCCCCATCTCTCCCTCCCCTGCCATTT
TGGGTTTTGGGTCTTTGAACCCTTGCTTGCAATAGGTGTGCGTCAGAAGCACCCAGGACTTCCATTTGCTTTGTCCCGGG
GCTCCACTGAACAAGTTGGCCTGCACTGGTGTTTTGTTGTGGGGAGGAGGATGGGGAGTAGGACATACCAGCTTAGATTT
TAAGGTTTTTACTGTGAGGGATGTTTGGGAGATGTAAGAAATGTTCTTGCAGTTAAGGGTTAGTTTACAATCAGCCACAT
TCTAGGTAGGGGCCCACTTCACCGTACTAACCAGGGAAGCTGTCCCTCACTGTTGAATTTTCTCTAACTTCAAGGCCCAT
ATCTGTGAAATGCTGGCATTTGCACCTACCTCACAGAGTGCATTGTGAGGGTTAATGAAATAATGTACATCTGGCCTTGA
AACCACCTTTTATTACATGGGGTCTAGAACTTGACCCCCTTGAGGGTGCTTGTTCCCTCTCCCTGTTGGTCGGTGGGTTG
GTAGTTTCTACAGTTGGGCAGCTGGTTAGGTAGAGGGAGTTGTCAAGTCTCTGCTGGCCCAGCCAAACCCTGTCTGACAA
CCTCTTGGTGAACCTTAGTACCTAAAAGGAAATCTCACCCCATCCCACACCCTGGAGGATTTCATCTCTTGTATATGATG
ATCTGGATCCACCAAGACTTGTTTTATGCTCAGGGTCAATTTCTTTTTTCTTTTTTTTTTTTTTTTTTCTTTTTCTTTGA
GACTGGGTCTCGCTTTGTTGCCCAGGCTGGAGTGGAGTGGCGTGATCTTGGCTTACTGCAGCCTTTGCCTCCCCGGCTCG
AGCAGTCCTGCCTCAGCCTCCGGAGTAGCTGGGACCACAGGTTCATGCCACCATGGCCAGCCAACTTTTGCATGTTTTGT
AGAGATGGGGTCTCACAGTGTTGCCCAGGCTGGTCTCAAACTCCTGGGCTCAGGCGATCCACCTGTCTCAGCCTCCCAGA
GTGCTGGGATTACAATTGTGAGCCACCACGTCCAGCTGGAAGGGTCAACATCTTTTACATTCTGCAAGCACATCTGCATT
TTCACCCCACCCTTCCCCTCCTTCTCCCTTTTTATATCCCATTTTTATATCGATCTCTTATTTTACAATAAAACTTTGCT
GCCACCTGTGTGTCTGAGGGGTGA