Feature key |
Position
|
Length
|
Description
|
Feature identifier
|
Region |
|
|
|
|
Dna binding
|
102 - 292
|
191
|
|
P04637-DNA_BIND-102
|
Motif
|
305 - 321
|
17
|
Bipartite nuclear localization signal
|
P04637-MOTIF-305
|
Motif
|
339 - 350
|
12
|
Nuclear export signal
|
P04637-MOTIF-339
|
Motif
|
370 - 372
|
3
|
[KR]-[STA]-K motif
|
P04637-MOTIF-370
|
Region
|
1 - 44
|
44
|
Transcription activation (acidic)
|
P04637-REGION-1
|
Region
|
66 - 110
|
45
|
Interaction with WWOX
|
P04637-REGION-66
|
Region
|
100 - 370
|
271
|
Interaction with HIPK1 (By similarity)
|
P04637-REGION-100
|
Region
|
113 - 236
|
124
|
Required for interaction with FBXO42
|
P04637-REGION-113
|
Region
|
116 - 292
|
177
|
Interaction with AXIN1 (By similarity)
|
P04637-REGION-116
|
Region
|
241 - 248
|
8
|
Interacts with the 53BP2 SH3 domain
|
P04637-REGION-241
|
Region
|
256 - 294
|
39
|
Interaction with E4F1
|
P04637-REGION-256
|
Region
|
300 - 393
|
94
|
Interaction with CARM1
|
P04637-REGION-300
|
Region
|
319 - 360
|
42
|
Interaction with HIPK2
|
P04637-REGION-319
|
Region
|
325 - 356
|
32
|
Oligomerization
|
P04637-REGION-325
|
Region
|
359 - 363
|
5
|
Interaction with USP7
|
P04637-REGION-359
|
Region
|
368 - 387
|
20
|
Basic (repression of DNA-binding)
|
P04637-REGION-368
|
Sites |
|
|
|
|
Metal binding
|
176 - 176
|
1
|
Zinc
|
P04637-METAL-176
|
Metal binding
|
179 - 179
|
1
|
Zinc
|
P04637-METAL-179
|
Metal binding
|
238 - 238
|
1
|
Zinc
|
P04637-METAL-238
|
Metal binding
|
242 - 242
|
1
|
Zinc
|
P04637-METAL-242
|
Natural variations |
|
|
|
|
Natural variant site
|
5 - 5
|
1
|
Q -> H (in a sporadic cancer; somatic mutation)
|
VAR_044543
|
Natural variant site
|
6 - 6
|
1
|
S -> L (in a sporadic cancer; somatic mutation)
|
VAR_044544
|
Natural variant site
|
7 - 7
|
1
|
D -> H (in a sporadic cancer; somatic mutation)
|
VAR_005851
|
Natural variant site
|
8 - 8
|
1
|
P -> S (in a sporadic cancer; somatic mutation)
|
VAR_044545
|
Natural variant site
|
10 - 10
|
1
|
V -> I (in a sporadic cancer; somatic mutation)
|
VAR_044546
|
Natural variant site
|
11 - 11
|
1
|
E -> Q (in sporadic cancers; somatic mutation)
|
VAR_044548
|
Natural variant site
|
11 - 11
|
1
|
E -> K (in sporadic cancers; somatic mutation)
|
VAR_044547
|
Natural variant site
|
15 - 15
|
1
|
S -> R (in a sporadic cancer; somatic mutation)
|
VAR_044549
|
Natural variant site
|
16 - 16
|
1
|
Q -> L (in a sporadic cancer; somatic mutation)
|
VAR_044550
|
Natural variant site
|
17 - 17
|
1
|
E -> D (in a sporadic cancer; somatic mutation)
|
VAR_044551
|
Natural variant site
|
24 - 24
|
1
|
K -> N (in a sporadic cancer; somatic mutation)
|
VAR_044552
|
Natural variant site
|
28 - 28
|
1
|
E -> A (in a sporadic cancer; somatic mutation)
|
VAR_044553
|
Natural variant site
|
29 - 30
|
2
|
NN -> KD (in a sporadic cancer; somatic mutation)
|
VAR_047158
|
Natural variant site
|
31 - 31
|
1
|
V -> I (in sporadic cancers; somatic mutation)
|
VAR_044554
|
Natural variant site
|
33 - 33
|
1
|
S -> T (in a sporadic cancer; somatic mutation)
|
VAR_044555
|
Natural variant site
|
34 - 34
|
1
|
P -> L (in a sporadic cancer; somatic mutation)
|
VAR_044556
|
Natural variant site
|
35 - 35
|
1
|
L -> F (in sporadic cancers; somatic mutation)
|
VAR_005852
|
Natural variant site
|
36 - 36
|
1
|
P -> L (in a sporadic cancer; somatic mutation)
|
VAR_044557
|
Natural variant site
|
37 - 37
|
1
|
S -> T (in a sporadic cancer; somatic mutation)
|
VAR_044559
|
Natural variant site
|
37 - 37
|
1
|
S -> P (in a sporadic cancer; somatic mutation)
|
VAR_044558
|
Natural variant site
|
39 - 39
|
1
|
A -> P (in a sporadic cancer; somatic mutation)
|
VAR_044560
|
Natural variant site
|
39 - 39
|
1
|
A -> V (in a sporadic cancer; somatic mutation)
|
VAR_044561
|
Natural variant site
|
42 - 42
|
1
|
D -> Y (in a sporadic cancer; somatic mutation)
|
VAR_044562
|
Natural variant site
|
43 - 43
|
1
|
L -> S (in a sporadic cancer; somatic mutation)
|
VAR_005853
|
Natural variant site
|
44 - 44
|
1
|
M -> I (in a sporadic cancer; somatic mutation)
|
VAR_044563
|
Natural variant site
|
44 - 44
|
1
|
M -> V (in a sporadic cancer; somatic mutation)
|
VAR_044565
|
Natural variant site
|
44 - 44
|
1
|
M -> T (in a sporadic cancer; somatic mutation)
|
VAR_044564
|
Natural variant site
|
45 - 45
|
1
|
L -> M (in a sporadic cancer; somatic mutation)
|
VAR_044566
|
Natural variant site
|
46 - 46
|
1
|
S -> P (in sporadic cancers; somatic mutation)
|
VAR_044568
|
Natural variant site
|
46 - 46
|
1
|
S -> F (in sporadic cancers; somatic mutation)
|
VAR_044567
|
Natural variant site
|
47 - 47
|
1
|
P -> L (in sporadic cancers; somatic mutation)
|
VAR_044569
|
Natural variant site
|
47 - 47
|
1
|
P -> S (in dbSNP:rs1800371)
|
VAR_014632
|
Natural variant site
|
48 - 48
|
1
|
D -> G (in a sporadic cancer; somatic mutation)
|
VAR_044570
|
Natural variant site
|
49 - 49
|
1
|
D -> N (in a sporadic cancer; somatic mutation)
|
VAR_044572
|
Natural variant site
|
49 - 49
|
1
|
D -> Y (in sporadic cancers; somatic mutation)
|
VAR_044573
|
Natural variant site
|
49 - 49
|
1
|
D -> H (in sporadic cancers; somatic mutation)
|
VAR_044571
|
Natural variant site
|
52 - 52
|
1
|
Q -> H (in a sporadic cancer; somatic mutation)
|
VAR_044574
|
Natural variant site
|
53 - 53
|
1
|
W -> G (in a sporadic cancer; somatic mutation)
|
VAR_044575
|
Natural variant site
|
53 - 53
|
1
|
W -> C (in sporadic cancers; somatic mutation)
|
VAR_005854
|
Natural variant site
|
54 - 54
|
1
|
F -> Y (in a sporadic cancer; somatic mutation)
|
VAR_044577
|
Natural variant site
|
54 - 54
|
1
|
F -> L (in a sporadic cancer; somatic mutation)
|
VAR_044576
|
Natural variant site
|
56 - 56
|
1
|
E -> K (in sporadic cancers; somatic mutation)
|
VAR_044578
|
Natural variant site
|
56 - 56
|
1
|
E -> V (in a sporadic cancer; somatic mutation)
|
VAR_044579
|
Natural variant site
|
58 - 58
|
1
|
P -> T (in a sporadic cancer; somatic mutation)
|
VAR_044581
|
Natural variant site
|
58 - 58
|
1
|
P -> Q (in a sporadic cancer; somatic mutation)
|
VAR_044580
|
Natural variant site
|
59 - 59
|
1
|
G -> N (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045783
|
Natural variant site
|
59 - 59
|
1
|
G -> C (in sporadic cancers; somatic mutation)
|
VAR_044582
|
Natural variant site
|
59 - 59
|
1
|
G -> D (in sporadic cancers; somatic mutation)
|
VAR_044583
|
Natural variant site
|
60 - 60
|
1
|
P -> S (in a sporadic cancer; somatic mutation)
|
VAR_005855
|
Natural variant site
|
60 - 60
|
1
|
P -> Q (in a sporadic cancer; somatic mutation)
|
VAR_044585
|
Natural variant site
|
60 - 60
|
1
|
P -> L (in sporadic cancers; somatic mutation)
|
VAR_044584
|
Natural variant site
|
61 - 61
|
1
|
D -> N (in sporadic cancers; somatic mutation)
|
VAR_044587
|
Natural variant site
|
61 - 61
|
1
|
D -> G (in sporadic cancers; somatic mutation)
|
VAR_044586
|
Natural variant site
|
62 - 62
|
1
|
E -> D (in a sporadic cancer; somatic mutation)
|
VAR_044588
|
Natural variant site
|
63 - 63
|
1
|
A -> V (in a sporadic cancer; somatic mutation)
|
VAR_044590
|
Natural variant site
|
63 - 63
|
1
|
A -> T (in a sporadic cancer; somatic mutation)
|
VAR_044589
|
Natural variant site
|
65 - 65
|
1
|
R -> T (in a sporadic cancer; somatic mutation)
|
VAR_044591
|
Natural variant site
|
66 - 66
|
1
|
M -> I (in a sporadic cancer; somatic mutation)
|
VAR_044592
|
Natural variant site
|
66 - 66
|
1
|
M -> R (in a sporadic cancer; somatic mutation)
|
VAR_044593
|
Natural variant site
|
67 - 67
|
1
|
P -> R (in a sporadic cancer; somatic mutation)
|
VAR_044595
|
Natural variant site
|
67 - 67
|
1
|
P -> S (in sporadic cancers; somatic mutation)
|
VAR_044596
|
Natural variant site
|
67 - 67
|
1
|
P -> L (in sporadic cancers; somatic mutation)
|
VAR_044594
|
Natural variant site
|
68 - 68
|
1
|
E -> Q (in a sporadic cancer; somatic mutation)
|
VAR_044598
|
Natural variant site
|
68 - 68
|
1
|
E -> G (in sporadic cancers; somatic mutation)
|
VAR_044597
|
Natural variant site
|
69 - 69
|
1
|
A -> G (in sporadic cancers; somatic mutation)
|
VAR_044600
|
Natural variant site
|
69 - 69
|
1
|
A -> V (in a sporadic cancer; somatic mutation)
|
VAR_044602
|
Natural variant site
|
69 - 69
|
1
|
A -> T (in a sporadic cancer; somatic mutation)
|
VAR_044601
|
Natural variant site
|
69 - 69
|
1
|
A -> D (in a sporadic cancer; somatic mutation)
|
VAR_044599
|
Natural variant site
|
70 - 70
|
1
|
A -> T (in a sporadic cancer; somatic mutation)
|
VAR_044603
|
Natural variant site
|
71 - 71
|
1
|
P -> T (in a sporadic cancer; somatic mutation)
|
VAR_044604
|
Natural variant site
|
72 - 72
|
1
|
P -> R (in dbSNP:rs1042522)
|
VAR_005856
|
Natural variant site
|
72 - 72
|
1
|
P -> G (in sporadic cancers; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045785
|
Natural variant site
|
72 - 72
|
1
|
P -> H (in sporadic cancers; somatic mutation)
|
VAR_045786
|
Natural variant site
|
72 - 72
|
1
|
P -> L (in a sporadic cancer; somatic mutation)
|
VAR_045787
|
Natural variant site
|
72 - 72
|
1
|
P -> C (in sporadic cancers; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045784
|
Natural variant site
|
73 - 73
|
1
|
V -> M (in sporadic cancers; somatic mutation)
|
VAR_044607
|
Natural variant site
|
73 - 73
|
1
|
V -> L (in sporadic cancers; somatic mutation)
|
VAR_044606
|
Natural variant site
|
73 - 73
|
1
|
V -> E (in a sporadic cancer; somatic mutation)
|
VAR_044605
|
Natural variant site
|
74 - 74
|
1
|
A -> T (in a sporadic cancer; somatic mutation)
|
VAR_044608
|
Natural variant site
|
75 - 75
|
1
|
P -> L (in sporadic cancers; somatic mutation)
|
VAR_044609
|
Natural variant site
|
75 - 75
|
1
|
P -> R (in sporadic cancers; somatic mutation)
|
VAR_044610
|
Natural variant site
|
75 - 75
|
1
|
P -> S (in a sporadic cancer; somatic mutation)
|
VAR_044611
|
Natural variant site
|
76 - 76
|
1
|
A -> G (in a sporadic cancer; somatic mutation)
|
VAR_044612
|
Natural variant site
|
76 - 76
|
1
|
A -> T (in a sporadic cancer; somatic mutation)
|
VAR_044613
|
Natural variant site
|
77 - 77
|
1
|
P -> A (in sporadic cancers; somatic mutation)
|
VAR_044614
|
Natural variant site
|
78 - 78
|
1
|
A -> V (in sporadic cancers; somatic mutation)
|
VAR_044615
|
Natural variant site
|
79 - 79
|
1
|
A -> G (in a sporadic cancer; somatic mutation)
|
VAR_044616
|
Natural variant site
|
79 - 79
|
1
|
A -> V (in sporadic cancers; somatic mutation)
|
VAR_044617
|
Natural variant site
|
79 - 79
|
1
|
A -> T (in a sporadic cancer; somatic mutation)
|
VAR_005857
|
Natural variant site
|
80 - 80
|
1
|
P -> L (in a sporadic cancer; somatic mutation)
|
VAR_044618
|
Natural variant site
|
80 - 80
|
1
|
P -> S (in a sporadic cancer; somatic mutation)
|
VAR_044619
|
Natural variant site
|
81 - 81
|
1
|
T -> I (in sporadic cancers; somatic mutation)
|
VAR_044620
|
Natural variant site
|
82 - 82
|
1
|
P -> L (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_044621
|
Natural variant site
|
82 - 82
|
1
|
P -> S (in sporadic cancers; somatic mutation)
|
VAR_044622
|
Natural variant site
|
83 - 83
|
1
|
A -> V (in sporadic cancers; somatic mutation)
|
VAR_044624
|
Natural variant site
|
83 - 83
|
1
|
A -> E (in a sporadic cancer; somatic mutation)
|
VAR_044623
|
Natural variant site
|
84 - 84
|
1
|
A -> G (in sporadic cancers; somatic mutation)
|
VAR_044625
|
Natural variant site
|
84 - 84
|
1
|
A -> V (in sporadic cancers; somatic mutation)
|
VAR_044626
|
Natural variant site
|
85 - 85
|
1
|
P -> L (in sporadic cancers; somatic mutation)
|
VAR_044627
|
Natural variant site
|
85 - 85
|
1
|
P -> S (in sporadic cancers; somatic mutation)
|
VAR_044628
|
Natural variant site
|
86 - 86
|
1
|
A -> V (in a sporadic cancer; somatic mutation)
|
VAR_044629
|
Natural variant site
|
87 - 87
|
1
|
P -> Q (in sporadic cancers; somatic mutation)
|
VAR_005858
|
Natural variant site
|
88 - 88
|
1
|
A -> V (in sporadic cancers; somatic mutation)
|
VAR_044631
|
Natural variant site
|
88 - 88
|
1
|
A -> T (in a sporadic cancer; somatic mutation)
|
VAR_044630
|
Natural variant site
|
89 - 89
|
1
|
P -> S (in sporadic cancers; somatic mutation)
|
VAR_044633
|
Natural variant site
|
89 - 89
|
1
|
P -> L (in sporadic cancers; somatic mutation)
|
VAR_044632
|
Natural variant site
|
90 - 90
|
1
|
S -> Y (in a sporadic cancer; somatic mutation)
|
VAR_044635
|
Natural variant site
|
90 - 90
|
1
|
S -> F (in sporadic cancers; somatic mutation)
|
VAR_044634
|
Natural variant site
|
91 - 91
|
1
|
W -> C (in a sporadic cancer; somatic mutation)
|
VAR_044636
|
Natural variant site
|
92 - 92
|
1
|
P -> L (in a sporadic cancer; somatic mutation)
|
VAR_044638
|
Natural variant site
|
92 - 92
|
1
|
P -> A (in a sporadic cancer; somatic mutation)
|
VAR_044637
|
Natural variant site
|
92 - 92
|
1
|
P -> S (in a sporadic cancer; somatic mutation)
|
VAR_044639
|
Natural variant site
|
93 - 93
|
1
|
L -> P (in a sporadic cancer; somatic mutation)
|
VAR_044641
|
Natural variant site
|
93 - 93
|
1
|
L -> M (in a sporadic cancer; somatic mutation)
|
VAR_044640
|
Natural variant site
|
94 - 94
|
1
|
S -> T (in sporadic cancers; somatic mutation)
|
VAR_005859
|
Natural variant site
|
94 - 94
|
1
|
S -> L (in sporadic cancers; somatic mutation)
|
VAR_044642
|
Natural variant site
|
95 - 95
|
1
|
S -> T (in a sporadic cancer; somatic mutation)
|
VAR_044644
|
Natural variant site
|
95 - 95
|
1
|
S -> F (in sporadic cancers; somatic mutation)
|
VAR_044643
|
Natural variant site
|
96 - 96
|
1
|
S -> P (in a sporadic cancer; somatic mutation)
|
VAR_044647
|
Natural variant site
|
96 - 96
|
1
|
S -> C (in a sporadic cancer; somatic mutation)
|
VAR_044645
|
Natural variant site
|
96 - 96
|
1
|
S -> F (in sporadic cancers; somatic mutation)
|
VAR_044646
|
Natural variant site
|
97 - 97
|
1
|
V -> F (in a sporadic cancer; somatic mutation)
|
VAR_044649
|
Natural variant site
|
97 - 97
|
1
|
V -> A (in a sporadic cancer; somatic mutation)
|
VAR_044648
|
Natural variant site
|
97 - 97
|
1
|
V -> I (in familial cancer not matching LFS; germline mutation and in a sporadic cancer; somatic mutation)
|
VAR_044650
|
Natural variant site
|
98 - 98
|
1
|
P -> S (in sporadic cancers; somatic mutation)
|
VAR_044652
|
Natural variant site
|
98 - 98
|
1
|
P -> L (in sporadic cancers; somatic mutation)
|
VAR_044651
|
Natural variant site
|
99 - 99
|
1
|
S -> F (in sporadic cancers; somatic mutation)
|
VAR_044653
|
Natural variant site
|
99 - 99
|
1
|
S -> P (in a sporadic cancer; somatic mutation)
|
VAR_044654
|
Natural variant site
|
100 - 100
|
1
|
Q -> R (in a sporadic cancer; somatic mutation)
|
VAR_044655
|
Natural variant site
|
101 - 101
|
1
|
K -> N (in a sporadic cancer; somatic mutation)
|
VAR_044656
|
Natural variant site
|
101 - 101
|
1
|
K -> R (in sporadic cancers; somatic mutation)
|
VAR_044657
|
Natural variant site
|
102 - 102
|
1
|
T -> I (in sporadic cancers; somatic mutation)
|
VAR_044658
|
Natural variant site
|
104 - 104
|
1
|
Q -> H (in sporadic cancers; somatic mutation)
|
VAR_044659
|
Natural variant site
|
104 - 104
|
1
|
Q -> L (in a sporadic cancer; somatic mutation)
|
VAR_044660
|
Natural variant site
|
105 - 105
|
1
|
G -> S (in a sporadic cancer; somatic mutation)
|
VAR_044664
|
Natural variant site
|
105 - 105
|
1
|
G -> V (in sporadic cancers; somatic mutation)
|
VAR_044665
|
Natural variant site
|
105 - 105
|
1
|
G -> R (in sporadic cancers; somatic mutation)
|
VAR_044663
|
Natural variant site
|
105 - 105
|
1
|
G -> D (in sporadic cancers; somatic mutation)
|
VAR_044662
|
Natural variant site
|
105 - 105
|
1
|
G -> C (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_044661
|
Natural variant site
|
106 - 106
|
1
|
S -> R (in a familial cancer not matching LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_044667
|
Natural variant site
|
106 - 106
|
1
|
S -> G (in a sporadic cancer; somatic mutation)
|
VAR_044666
|
Natural variant site
|
107 - 107
|
1
|
Y -> C (in a sporadic cancer; somatic mutation)
|
VAR_044668
|
Natural variant site
|
107 - 107
|
1
|
Y -> H (in a sporadic cancer; somatic mutation)
|
VAR_044670
|
Natural variant site
|
107 - 107
|
1
|
Y -> D (in sporadic cancers; somatic mutation)
|
VAR_044669
|
Natural variant site
|
108 - 108
|
1
|
G -> S (in sporadic cancers; somatic mutation)
|
VAR_044672
|
Natural variant site
|
108 - 108
|
1
|
G -> D (in a sporadic cancer; somatic mutation)
|
VAR_044671
|
Natural variant site
|
109 - 109
|
1
|
F -> L (in a sporadic cancer; somatic mutation)
|
VAR_044674
|
Natural variant site
|
109 - 109
|
1
|
F -> S (in sporadic cancers; somatic mutation)
|
VAR_044675
|
Natural variant site
|
109 - 109
|
1
|
F -> C (in sporadic cancers; somatic mutation)
|
VAR_044673
|
Natural variant site
|
110 - 110
|
1
|
R -> G (in a sporadic cancer; somatic mutation)
|
VAR_044676
|
Natural variant site
|
110 - 110
|
1
|
R -> H (in sporadic cancers; somatic mutation)
|
VAR_044677
|
Natural variant site
|
110 - 110
|
1
|
R -> S (in a sporadic cancer; somatic mutation)
|
VAR_044678
|
Natural variant site
|
110 - 110
|
1
|
R -> C (in sporadic cancers; somatic mutation)
|
VAR_005860
|
Natural variant site
|
110 - 110
|
1
|
R -> L (in a familial cancer not matching LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_005861
|
Natural variant site
|
110 - 110
|
1
|
R -> P (in sporadic cancers; somatic mutation; dbSNP:rs11540654)
|
VAR_005862
|
Natural variant site
|
111 - 111
|
1
|
L -> P (in sporadic cancers; somatic mutation)
|
VAR_044680
|
Natural variant site
|
111 - 111
|
1
|
L -> Q (in sporadic cancers; somatic mutation)
|
VAR_044681
|
Natural variant site
|
111 - 111
|
1
|
L -> R (in sporadic cancers; somatic mutation)
|
VAR_044682
|
Natural variant site
|
111 - 111
|
1
|
L -> M (in a sporadic cancer; somatic mutation)
|
VAR_044679
|
Natural variant site
|
112 - 112
|
1
|
G -> D (in sporadic cancers; somatic mutation)
|
VAR_044683
|
Natural variant site
|
112 - 112
|
1
|
G -> S (in sporadic cancers; somatic mutation)
|
VAR_044684
|
Natural variant site
|
113 - 113
|
1
|
F -> C (in sporadic cancers; somatic mutation)
|
VAR_005863
|
Natural variant site
|
113 - 113
|
1
|
F -> G (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045788
|
Natural variant site
|
113 - 113
|
1
|
F -> S (in sporadic cancers; somatic mutation)
|
VAR_044687
|
Natural variant site
|
113 - 113
|
1
|
F -> I (in a sporadic cancer; somatic mutation)
|
VAR_044685
|
Natural variant site
|
113 - 113
|
1
|
F -> L (in sporadic cancers; somatic mutation)
|
VAR_044686
|
Natural variant site
|
113 - 113
|
1
|
F -> V (in sporadic cancers; somatic mutation)
|
VAR_033033
|
Natural variant site
|
115 - 115
|
1
|
H -> Y (in sporadic cancers; somatic mutation)
|
VAR_044688
|
Natural variant site
|
116 - 116
|
1
|
S -> P (in a sporadic cancer; somatic mutation)
|
VAR_044691
|
Natural variant site
|
116 - 116
|
1
|
S -> F (in a sporadic cancer; somatic mutation)
|
VAR_044690
|
Natural variant site
|
116 - 116
|
1
|
S -> C (in sporadic cancers; somatic mutation)
|
VAR_044689
|
Natural variant site
|
117 - 117
|
1
|
G -> E (in sporadic cancers; somatic mutation)
|
VAR_044692
|
Natural variant site
|
117 - 117
|
1
|
G -> R (in sporadic cancers; somatic mutation)
|
VAR_044693
|
Natural variant site
|
118 - 118
|
1
|
T -> I (in sporadic cancers; somatic mutation)
|
VAR_044695
|
Natural variant site
|
118 - 118
|
1
|
T -> R (in a sporadic cancer; somatic mutation)
|
VAR_044696
|
Natural variant site
|
118 - 118
|
1
|
T -> A (in a sporadic cancer; somatic mutation)
|
VAR_044694
|
Natural variant site
|
119 - 119
|
1
|
A -> D (in a sporadic cancer; somatic mutation)
|
VAR_044697
|
Natural variant site
|
119 - 119
|
1
|
A -> T (in a sporadic cancer; somatic mutation)
|
VAR_044698
|
Natural variant site
|
120 - 120
|
1
|
K -> E (in sporadic cancers; somatic mutation)
|
VAR_044699
|
Natural variant site
|
120 - 120
|
1
|
K -> R (in sporadic cancers; somatic mutation)
|
VAR_044702
|
Natural variant site
|
120 - 120
|
1
|
K -> M (in sporadic cancers; somatic mutation)
|
VAR_044700
|
Natural variant site
|
120 - 120
|
1
|
K -> Q (in a sporadic cancer; somatic mutation)
|
VAR_044701
|
Natural variant site
|
121 - 121
|
1
|
S -> F (in sporadic cancers; somatic mutation)
|
VAR_044703
|
Natural variant site
|
122 - 122
|
1
|
V -> L (in a sporadic cancer; somatic mutation)
|
VAR_044704
|
Natural variant site
|
123 - 123
|
1
|
T -> I (in a sporadic cancer; somatic mutation)
|
VAR_044705
|
Natural variant site
|
123 - 123
|
1
|
T -> N (in a sporadic cancer; somatic mutation)
|
VAR_044706
|
Natural variant site
|
124 - 124
|
1
|
C -> R (in sporadic cancers; somatic mutation)
|
VAR_044708
|
Natural variant site
|
124 - 124
|
1
|
C -> S (in sporadic cancers; somatic mutation)
|
VAR_044709
|
Natural variant site
|
124 - 124
|
1
|
C -> G (in a sporadic cancer; somatic mutation)
|
VAR_044707
|
Natural variant site
|
124 - 124
|
1
|
C -> W (in a sporadic cancer; somatic mutation)
|
VAR_044710
|
Natural variant site
|
124 - 124
|
1
|
C -> Y (in a sporadic cancer; somatic mutation)
|
VAR_044711
|
Natural variant site
|
125 - 125
|
1
|
T -> P (in a sporadic cancer; somatic mutation)
|
VAR_044714
|
Natural variant site
|
125 - 125
|
1
|
T -> R (in sporadic cancers; somatic mutation)
|
VAR_044715
|
Natural variant site
|
125 - 125
|
1
|
T -> K (in sporadic cancers; somatic mutation)
|
VAR_044713
|
Natural variant site
|
125 - 125
|
1
|
T -> A (in a sporadic cancer; somatic mutation)
|
VAR_044712
|
Natural variant site
|
125 - 125
|
1
|
T -> M (in sporadic cancers; somatic mutation)
|
VAR_005864
|
Natural variant site
|
126 - 126
|
1
|
Y -> N (in sporadic cancers; somatic mutation)
|
VAR_005866
|
Natural variant site
|
126 - 126
|
1
|
Y -> G (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045789
|
Natural variant site
|
126 - 126
|
1
|
Y -> C (in a familial cancer not matching LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_044716
|
Natural variant site
|
126 - 126
|
1
|
Y -> H (in sporadic cancers; somatic mutation)
|
VAR_044718
|
Natural variant site
|
126 - 126
|
1
|
Y -> D (in sporadic cancers; somatic mutation)
|
VAR_005865
|
Natural variant site
|
126 - 126
|
1
|
Y -> S (in sporadic cancers; somatic mutation)
|
VAR_044719
|
Natural variant site
|
126 - 126
|
1
|
Y -> F (in a sporadic cancer; somatic mutation)
|
VAR_044717
|
Natural variant site
|
127 - 127
|
1
|
S -> T (in sporadic cancers; somatic mutation)
|
VAR_044722
|
Natural variant site
|
127 - 127
|
1
|
S -> Y (in sporadic cancers; somatic mutation)
|
VAR_044723
|
Natural variant site
|
127 - 127
|
1
|
S -> P (in sporadic cancers; somatic mutation)
|
VAR_044721
|
Natural variant site
|
127 - 127
|
1
|
S -> F (in sporadic cancers; somatic mutation)
|
VAR_005867
|
Natural variant site
|
127 - 127
|
1
|
S -> C (in a sporadic cancer; somatic mutation)
|
VAR_044720
|
Natural variant site
|
128 - 128
|
1
|
P -> S (in sporadic cancers; somatic mutation)
|
VAR_005868
|
Natural variant site
|
128 - 128
|
1
|
P -> L (in sporadic cancers; somatic mutation)
|
VAR_044725
|
Natural variant site
|
128 - 128
|
1
|
P -> A (in sporadic cancers; somatic mutation)
|
VAR_044724
|
Natural variant site
|
128 - 128
|
1
|
P -> R (in sporadic cancers; somatic mutation)
|
VAR_044726
|
Natural variant site
|
129 - 129
|
1
|
A -> G (in a sporadic cancer; somatic mutation)
|
VAR_044727
|
Natural variant site
|
129 - 129
|
1
|
A -> V (in sporadic cancers; somatic mutation)
|
VAR_044729
|
Natural variant site
|
129 - 129
|
1
|
A -> D (in sporadic cancers; somatic mutation)
|
VAR_005869
|
Natural variant site
|
129 - 129
|
1
|
A -> T (in sporadic cancers; somatic mutation)
|
VAR_044728
|
Natural variant site
|
130 - 130
|
1
|
L -> V (in sporadic cancers; somatic mutation)
|
VAR_044734
|
Natural variant site
|
130 - 130
|
1
|
L -> P (in sporadic cancers; somatic mutation)
|
VAR_044733
|
Natural variant site
|
130 - 130
|
1
|
L -> I (in a sporadic cancer; somatic mutation)
|
VAR_044732
|
Natural variant site
|
130 - 130
|
1
|
L -> H (in sporadic cancers; somatic mutation)
|
VAR_044731
|
Natural variant site
|
130 - 130
|
1
|
L -> F (in sporadic cancers; somatic mutation)
|
VAR_044730
|
Natural variant site
|
130 - 130
|
1
|
L -> R (in sporadic cancers; somatic mutation)
|
VAR_005870
|
Natural variant site
|
131 - 131
|
1
|
N -> S (in sporadic cancers; somatic mutation)
|
VAR_005871
|
Natural variant site
|
131 - 131
|
1
|
N -> D (in a sporadic cancer; somatic mutation)
|
VAR_044735
|
Natural variant site
|
131 - 131
|
1
|
N -> H (in sporadic cancers; somatic mutation)
|
VAR_044736
|
Natural variant site
|
131 - 131
|
1
|
N -> Y (in sporadic cancers; somatic mutation)
|
VAR_044739
|
Natural variant site
|
131 - 131
|
1
|
N -> K (in sporadic cancers; somatic mutation)
|
VAR_005872
|
Natural variant site
|
131 - 131
|
1
|
N -> T (in a sporadic cancer; somatic mutation)
|
VAR_044738
|
Natural variant site
|
131 - 131
|
1
|
N -> I (in sporadic cancers; somatic mutation)
|
VAR_044737
|
Natural variant site
|
132 - 132
|
1
|
K -> W (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045791
|
Natural variant site
|
132 - 132
|
1
|
K -> R (in sporadic cancers; somatic mutation)
|
VAR_044742
|
Natural variant site
|
132 - 132
|
1
|
K -> E (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_044740
|
Natural variant site
|
132 - 132
|
1
|
K -> Q (in sporadic cancers; somatic mutation)
|
VAR_005874
|
Natural variant site
|
132 - 133
|
2
|
KM -> NL (in a sporadic cancer; somatic mutation)
|
VAR_047159
|
Natural variant site
|
132 - 132
|
1
|
K -> L (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045790
|
Natural variant site
|
132 - 132
|
1
|
K -> T (in sporadic cancers; somatic mutation)
|
VAR_044743
|
Natural variant site
|
132 - 132
|
1
|
K -> N (in sporadic cancers; somatic mutation)
|
VAR_044741
|
Natural variant site
|
132 - 132
|
1
|
K -> M (in sporadic cancers; somatic mutation)
|
VAR_005873
|
Natural variant site
|
133 - 133
|
1
|
M -> R (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_044747
|
Natural variant site
|
133 - 133
|
1
|
M -> V (in sporadic cancers; somatic mutation)
|
VAR_044748
|
Natural variant site
|
133 - 133
|
1
|
M -> T (in LFS; germline mutation and in sporadic cancers; somatic mutation; dbSNP:rs28934873)
|
VAR_005875
|
Natural variant site
|
133 - 133
|
1
|
M -> I (in sporadic cancers; somatic mutation)
|
VAR_044744
|
Natural variant site
|
133 - 133
|
1
|
M -> K (in sporadic cancers; somatic mutation)
|
VAR_044745
|
Natural variant site
|
133 - 133
|
1
|
M -> L (in sporadic cancers; somatic mutation)
|
VAR_044746
|
Natural variant site
|
134 - 134
|
1
|
F -> L (in sporadic cancers; somatic mutation)
|
VAR_036504
|
Natural variant site
|
134 - 134
|
1
|
F -> S (in sporadic cancers; somatic mutation)
|
VAR_044751
|
Natural variant site
|
134 - 134
|
1
|
F -> I (in sporadic cancers; somatic mutation)
|
VAR_044750
|
Natural variant site
|
134 - 134
|
1
|
F -> C (in sporadic cancers; somatic mutation)
|
VAR_044749
|
Natural variant site
|
134 - 134
|
1
|
F -> V (in sporadic cancers; somatic mutation)
|
VAR_044752
|
Natural variant site
|
135 - 135
|
1
|
C -> W (in sporadic cancers; somatic mutation)
|
VAR_044755
|
Natural variant site
|
135 - 135
|
1
|
C -> G (in sporadic cancers; somatic mutation)
|
VAR_044753
|
Natural variant site
|
135 - 135
|
1
|
C -> R (in sporadic cancers; somatic mutation)
|
VAR_044754
|
Natural variant site
|
135 - 135
|
1
|
C -> F (in sporadic cancers; somatic mutation)
|
VAR_005877
|
Natural variant site
|
135 - 135
|
1
|
C -> S (in sporadic cancers; somatic mutation)
|
VAR_005876
|
Natural variant site
|
135 - 135
|
1
|
C -> Y (in sporadic cancers; somatic mutation; decreased E6-mediated binding to E6-AP)
|
VAR_044756
|
Natural variant site
|
135 - 135
|
1
|
C -> T (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045792
|
Natural variant site
|
136 - 136
|
1
|
Q -> R (in sporadic cancers; somatic mutation)
|
VAR_044759
|
Natural variant site
|
136 - 136
|
1
|
Q -> H (in sporadic cancers; somatic mutation)
|
VAR_044757
|
Natural variant site
|
136 - 136
|
1
|
Q -> E (in sporadic cancers; somatic mutation)
|
VAR_005878
|
Natural variant site
|
136 - 136
|
1
|
Q -> P (in sporadic cancers; somatic mutation)
|
VAR_044758
|
Natural variant site
|
136 - 136
|
1
|
Q -> K (in a sporadic cancer; somatic mutation)
|
VAR_005879
|
Natural variant site
|
137 - 137
|
1
|
L -> V (in sporadic cancers; somatic mutation)
|
VAR_044762
|
Natural variant site
|
137 - 137
|
1
|
L -> Q (in sporadic cancers; somatic mutation)
|
VAR_005880
|
Natural variant site
|
137 - 137
|
1
|
L -> M (in sporadic cancers; somatic mutation)
|
VAR_044760
|
Natural variant site
|
137 - 137
|
1
|
L -> P (in sporadic cancers; somatic mutation)
|
VAR_044761
|
Natural variant site
|
138 - 138
|
1
|
A -> S (in LFS; germline mutation)
|
VAR_044764
|
Natural variant site
|
138 - 138
|
1
|
A -> P (in LFS; germline mutation and in sporadic cancers; somatic mutation; dbSNP:rs28934875)
|
VAR_005881
|
Natural variant site
|
138 - 138
|
1
|
A -> V (in sporadic cancers; somatic mutation)
|
VAR_033034
|
Natural variant site
|
138 - 138
|
1
|
A -> T (in sporadic cancers; somatic mutation)
|
VAR_044765
|
Natural variant site
|
138 - 138
|
1
|
A -> D (in sporadic cancers; somatic mutation)
|
VAR_044763
|
Natural variant site
|
139 - 139
|
1
|
K -> R (in sporadic cancers; somatic mutation)
|
VAR_044768
|
Natural variant site
|
139 - 139
|
1
|
K -> E (in sporadic cancers; somatic mutation)
|
VAR_044766
|
Natural variant site
|
139 - 139
|
1
|
K -> N (in sporadic cancers; somatic mutation)
|
VAR_005882
|
Natural variant site
|
139 - 139
|
1
|
K -> T (in sporadic cancers; somatic mutation)
|
VAR_044769
|
Natural variant site
|
139 - 139
|
1
|
K -> Q (in sporadic cancers; somatic mutation)
|
VAR_044767
|
Natural variant site
|
140 - 140
|
1
|
T -> P (in a sporadic cancer; somatic mutation)
|
VAR_044773
|
Natural variant site
|
140 - 140
|
1
|
T -> N (in a sporadic cancer; somatic mutation)
|
VAR_044772
|
Natural variant site
|
140 - 140
|
1
|
T -> I (in sporadic cancers; somatic mutation)
|
VAR_044771
|
Natural variant site
|
140 - 140
|
1
|
T -> S (in sporadic cancers; somatic mutation)
|
VAR_044774
|
Natural variant site
|
140 - 140
|
1
|
T -> A (in sporadic cancers; somatic mutation)
|
VAR_044770
|
Natural variant site
|
141 - 141
|
1
|
C -> A (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045793
|
Natural variant site
|
141 - 141
|
1
|
C -> R (in sporadic cancers; somatic mutation)
|
VAR_044775
|
Natural variant site
|
141 - 141
|
1
|
C -> G (in sporadic cancers; somatic mutation)
|
VAR_005884
|
Natural variant site
|
141 - 141
|
1
|
C -> Y (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_005886
|
Natural variant site
|
141 - 141
|
1
|
C -> F (in sporadic cancers; somatic mutation)
|
VAR_005885
|
Natural variant site
|
141 - 141
|
1
|
C -> W (in sporadic cancers; somatic mutation)
|
VAR_044777
|
Natural variant site
|
141 - 141
|
1
|
C -> S (in sporadic cancers; somatic mutation)
|
VAR_044776
|
Natural variant site
|
142 - 142
|
1
|
P -> H (in sporadic cancers; somatic mutation)
|
VAR_044779
|
Natural variant site
|
142 - 142
|
1
|
P -> R (in a sporadic cancer; somatic mutation)
|
VAR_044781
|
Natural variant site
|
142 - 142
|
1
|
P -> T (in sporadic cancers; somatic mutation)
|
VAR_044783
|
Natural variant site
|
142 - 142
|
1
|
P -> S (in sporadic cancers; somatic mutation)
|
VAR_044782
|
Natural variant site
|
142 - 142
|
1
|
P -> A (in sporadic cancers; somatic mutation)
|
VAR_044778
|
Natural variant site
|
142 - 142
|
1
|
P -> F (in sporadic cancers; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045794
|
Natural variant site
|
142 - 142
|
1
|
P -> L (in sporadic cancers; somatic mutation)
|
VAR_044780
|
Natural variant site
|
143 - 143
|
1
|
V -> M (in sporadic cancers; somatic mutation)
|
VAR_044787
|
Natural variant site
|
143 - 143
|
1
|
V -> E (in sporadic cancers; somatic mutation)
|
VAR_044784
|
Natural variant site
|
143 - 143
|
1
|
V -> G (in sporadic cancers; somatic mutation)
|
VAR_044785
|
Natural variant site
|
143 - 143
|
1
|
V -> L (in sporadic cancers; somatic mutation)
|
VAR_044786
|
Natural variant site
|
143 - 143
|
1
|
V -> A (in sporadic cancers; somatic mutation; strong DNA binding ability at 32.5 degrees Celsius; strong reduction of transcriptional activity at 37.5 degrees Celsius)
|
VAR_005887
|
Natural variant site
|
144 - 144
|
1
|
Q -> P (in sporadic cancers; somatic mutation)
|
VAR_005888
|
Natural variant site
|
144 - 144
|
1
|
Q -> H (in sporadic cancers; somatic mutation)
|
VAR_044788
|
Natural variant site
|
144 - 144
|
1
|
Q -> R (in sporadic cancers; somatic mutation)
|
VAR_044791
|
Natural variant site
|
144 - 144
|
1
|
Q -> L (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_044790
|
Natural variant site
|
144 - 144
|
1
|
Q -> K (in sporadic cancers; somatic mutation)
|
VAR_044789
|
Natural variant site
|
145 - 145
|
1
|
L -> V (in sporadic cancers; somatic mutation)
|
VAR_044794
|
Natural variant site
|
145 - 145
|
1
|
L -> Q (in sporadic cancers; somatic mutation)
|
VAR_005890
|
Natural variant site
|
145 - 145
|
1
|
L -> R (in sporadic cancers; somatic mutation)
|
VAR_044793
|
Natural variant site
|
145 - 145
|
1
|
L -> P (in sporadic cancers; somatic mutation)
|
VAR_005889
|
Natural variant site
|
145 - 145
|
1
|
L -> M (in sporadic cancers; somatic mutation)
|
VAR_044792
|
Natural variant site
|
146 - 146
|
1
|
W -> L (in sporadic cancers; somatic mutation)
|
VAR_044797
|
Natural variant site
|
146 - 146
|
1
|
W -> G (in sporadic cancers; somatic mutation)
|
VAR_044796
|
Natural variant site
|
146 - 146
|
1
|
W -> S (in sporadic cancers; somatic mutation)
|
VAR_044799
|
Natural variant site
|
146 - 146
|
1
|
W -> C (in a sporadic cancer; somatic mutation)
|
VAR_044795
|
Natural variant site
|
146 - 146
|
1
|
W -> R (in sporadic cancers; somatic mutation)
|
VAR_044798
|
Natural variant site
|
147 - 147
|
1
|
V -> D (in sporadic cancers; somatic mutation)
|
VAR_005891
|
Natural variant site
|
147 - 147
|
1
|
V -> A (in sporadic cancers; somatic mutation)
|
VAR_044800
|
Natural variant site
|
147 - 147
|
1
|
V -> G (in sporadic cancers; somatic mutation)
|
VAR_005892
|
Natural variant site
|
147 - 147
|
1
|
V -> E (in sporadic cancers; somatic mutation)
|
VAR_044801
|
Natural variant site
|
147 - 147
|
1
|
V -> F (in a sporadic cancer; somatic mutation)
|
VAR_044802
|
Natural variant site
|
147 - 147
|
1
|
V -> I (in sporadic cancers; somatic mutation)
|
VAR_044803
|
Natural variant site
|
148 - 148
|
1
|
D -> E (in sporadic cancers; somatic mutation)
|
VAR_044805
|
Natural variant site
|
148 - 148
|
1
|
D -> V (in sporadic cancers; somatic mutation)
|
VAR_044808
|
Natural variant site
|
148 - 148
|
1
|
D -> Y (in sporadic cancers; somatic mutation)
|
VAR_044809
|
Natural variant site
|
148 - 148
|
1
|
D -> G (in a sporadic cancer; somatic mutation)
|
VAR_044806
|
Natural variant site
|
148 - 148
|
1
|
D -> N (in sporadic cancers; somatic mutation)
|
VAR_044807
|
Natural variant site
|
148 - 148
|
1
|
D -> A (in a sporadic cancer; somatic mutation)
|
VAR_044804
|
Natural variant site
|
149 - 149
|
1
|
S -> P (in sporadic cancers; somatic mutation)
|
VAR_005893
|
Natural variant site
|
149 - 149
|
1
|
S -> F (in sporadic cancers; somatic mutation)
|
VAR_044810
|
Natural variant site
|
149 - 149
|
1
|
S -> T (in sporadic cancers; somatic mutation)
|
VAR_044811
|
Natural variant site
|
150 - 150
|
1
|
T -> P (in a sporadic cancer; somatic mutation)
|
VAR_044816
|
Natural variant site
|
150 - 150
|
1
|
T -> I (in sporadic cancers; somatic mutation)
|
VAR_044813
|
Natural variant site
|
150 - 150
|
1
|
T -> K (in sporadic cancers; somatic mutation)
|
VAR_044814
|
Natural variant site
|
150 - 150
|
1
|
T -> A (in a sporadic cancer; somatic mutation)
|
VAR_044812
|
Natural variant site
|
150 - 150
|
1
|
T -> R (in a sporadic cancer; somatic mutation)
|
VAR_044817
|
Natural variant site
|
150 - 150
|
1
|
T -> N (in a sporadic cancer; somatic mutation)
|
VAR_044815
|
Natural variant site
|
151 - 151
|
1
|
P -> A (in sporadic cancers; somatic mutation)
|
VAR_005894
|
Natural variant site
|
151 - 151
|
1
|
P -> S (in LFS; germline mutation and in sporadic cancers; somatic mutation; dbSNP:rs28934874)
|
VAR_005895
|
Natural variant site
|
151 - 151
|
1
|
P -> H (in sporadic cancers; somatic mutation)
|
VAR_044818
|
Natural variant site
|
151 - 151
|
1
|
P -> T (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_005896
|
Natural variant site
|
151 - 151
|
1
|
P -> R (in sporadic cancers; somatic mutation)
|
VAR_044820
|
Natural variant site
|
151 - 151
|
1
|
P -> L (in sporadic cancers; somatic mutation)
|
VAR_044819
|
Natural variant site
|
152 - 152
|
1
|
P -> Q (in sporadic cancers; somatic mutation)
|
VAR_044822
|
Natural variant site
|
152 - 152
|
1
|
P -> A (in sporadic cancers; somatic mutation)
|
VAR_044821
|
Natural variant site
|
152 - 152
|
1
|
P -> L (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_005897
|
Natural variant site
|
152 - 152
|
1
|
P -> T (in sporadic cancers; somatic mutation)
|
VAR_044824
|
Natural variant site
|
152 - 152
|
1
|
P -> R (in sporadic cancers; somatic mutation)
|
VAR_044823
|
Natural variant site
|
152 - 152
|
1
|
P -> S (in sporadic cancers; somatic mutation)
|
VAR_005898
|
Natural variant site
|
153 - 153
|
1
|
P -> H (in a sporadic cancer; somatic mutation)
|
VAR_044826
|
Natural variant site
|
153 - 153
|
1
|
P -> A (in sporadic cancers; somatic mutation)
|
VAR_044825
|
Natural variant site
|
153 - 153
|
1
|
P -> T (in sporadic cancers; somatic mutation)
|
VAR_005899
|
Natural variant site
|
153 - 153
|
1
|
P -> R (in a sporadic cancer; somatic mutation)
|
VAR_044828
|
Natural variant site
|
153 - 153
|
1
|
P -> F (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045795
|
Natural variant site
|
153 - 153
|
1
|
P -> L (in sporadic cancers; somatic mutation)
|
VAR_044827
|
Natural variant site
|
153 - 153
|
1
|
P -> S (in sporadic cancers; somatic mutation)
|
VAR_044829
|
Natural variant site
|
154 - 154
|
1
|
G -> A (in sporadic cancers; somatic mutation)
|
VAR_044830
|
Natural variant site
|
154 - 154
|
1
|
G -> I (in sporadic cancers; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045796
|
Natural variant site
|
154 - 154
|
1
|
G -> C (in a sporadic cancer; somatic mutation)
|
VAR_044831
|
Natural variant site
|
154 - 154
|
1
|
G -> D (in sporadic cancers; somatic mutation)
|
VAR_044832
|
Natural variant site
|
154 - 154
|
1
|
G -> V (in a brain tumor with no family history; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_005900
|
Natural variant site
|
154 - 154
|
1
|
G -> S (in sporadic cancers; somatic mutation)
|
VAR_044833
|
Natural variant site
|
155 - 155
|
1
|
T -> N (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_044836
|
Natural variant site
|
155 - 155
|
1
|
T -> I (in sporadic cancers; somatic mutation)
|
VAR_044834
|
Natural variant site
|
155 - 155
|
1
|
T -> P (in sporadic cancers; somatic mutation)
|
VAR_044837
|
Natural variant site
|
155 - 155
|
1
|
T -> A (in sporadic cancers; somatic mutation)
|
VAR_005901
|
Natural variant site
|
155 - 155
|
1
|
T -> S (in sporadic cancers; somatic mutation)
|
VAR_044838
|
Natural variant site
|
155 - 155
|
1
|
T -> M (in a sporadic cancer; somatic mutation)
|
VAR_044835
|
Natural variant site
|
156 - 156
|
1
|
R -> P (in sporadic cancers; somatic mutation)
|
VAR_005902
|
Natural variant site
|
156 - 156
|
1
|
R -> G (in sporadic cancers; somatic mutation)
|
VAR_044840
|
Natural variant site
|
156 - 156
|
1
|
R -> H (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_044841
|
Natural variant site
|
156 - 156
|
1
|
R -> L (in sporadic cancers; somatic mutation)
|
VAR_044842
|
Natural variant site
|
156 - 156
|
1
|
R -> S (in sporadic cancers; somatic mutation)
|
VAR_044843
|
Natural variant site
|
156 - 156
|
1
|
R -> C (in sporadic cancers; somatic mutation)
|
VAR_044839
|
Natural variant site
|
157 - 157
|
1
|
V -> I (in sporadic cancers; somatic mutation)
|
VAR_012977
|
Natural variant site
|
157 - 157
|
1
|
V -> F (in sporadic cancers; somatic mutation)
|
VAR_005904
|
Natural variant site
|
157 - 157
|
1
|
V -> A (in sporadic cancers; somatic mutation)
|
VAR_044844
|
Natural variant site
|
157 - 157
|
1
|
V -> G (in sporadic cancers; somatic mutation)
|
VAR_044845
|
Natural variant site
|
157 - 157
|
1
|
V -> L (in sporadic cancers; somatic mutation)
|
VAR_044846
|
Natural variant site
|
157 - 157
|
1
|
V -> D (in sporadic cancers; somatic mutation)
|
VAR_005903
|
Natural variant site
|
158 - 158
|
1
|
R -> L (in sporadic cancers; somatic mutation)
|
VAR_044847
|
Natural variant site
|
158 - 158
|
1
|
R -> Y (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045798
|
Natural variant site
|
158 - 158
|
1
|
R -> G (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_005906
|
Natural variant site
|
158 - 158
|
1
|
R -> C (in sporadic cancers; somatic mutation)
|
VAR_005905
|
Natural variant site
|
158 - 158
|
1
|
R -> H (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_005907
|
Natural variant site
|
158 - 158
|
1
|
R -> F (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045797
|
Natural variant site
|
158 - 158
|
1
|
R -> P (in sporadic cancers; somatic mutation)
|
VAR_044848
|
Natural variant site
|
158 - 158
|
1
|
R -> Q (in a sporadic cancer; somatic mutation)
|
VAR_044849
|
Natural variant site
|
158 - 158
|
1
|
R -> S (in sporadic cancers; somatic mutation)
|
VAR_044850
|
Natural variant site
|
159 - 159
|
1
|
A -> S (in sporadic cancers; somatic mutation)
|
VAR_044854
|
Natural variant site
|
159 - 159
|
1
|
A -> V (in sporadic cancers; somatic mutation)
|
VAR_044856
|
Natural variant site
|
159 - 159
|
1
|
A -> T (in sporadic cancers; somatic mutation)
|
VAR_044855
|
Natural variant site
|
159 - 159
|
1
|
A -> D (in sporadic cancers; somatic mutation)
|
VAR_044851
|
Natural variant site
|
159 - 159
|
1
|
A -> P (in sporadic cancers; somatic mutation)
|
VAR_044853
|
Natural variant site
|
159 - 159
|
1
|
A -> G (in sporadic cancers; somatic mutation)
|
VAR_044852
|
Natural variant site
|
159 - 159
|
1
|
A -> F (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045799
|
Natural variant site
|
160 - 161
|
2
|
MA -> IS (in sporadic cancers; somatic mutation)
|
VAR_047161
|
Natural variant site
|
160 - 160
|
1
|
M -> K (in sporadic cancers; somatic mutation)
|
VAR_044857
|
Natural variant site
|
160 - 160
|
1
|
M -> V (in sporadic cancers; somatic mutation)
|
VAR_044859
|
Natural variant site
|
160 - 160
|
1
|
M -> T (in a sporadic cancer; somatic mutation)
|
VAR_044858
|
Natural variant site
|
160 - 160
|
1
|
M -> I (in sporadic cancers; somatic mutation)
|
VAR_005908
|
Natural variant site
|
160 - 161
|
2
|
MA -> IP (in a sporadic cancer; somatic mutation)
|
VAR_047160
|
Natural variant site
|
160 - 161
|
2
|
MA -> IT (in a sporadic cancer; somatic mutation)
|
VAR_047162
|
Natural variant site
|
161 - 161
|
1
|
A -> T (in sporadic cancers; somatic mutation)
|
VAR_044863
|
Natural variant site
|
161 - 161
|
1
|
A -> F (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045800
|
Natural variant site
|
161 - 161
|
1
|
A -> S (in sporadic cancers; somatic mutation)
|
VAR_005909
|
Natural variant site
|
161 - 161
|
1
|
A -> D (in sporadic cancers; somatic mutation)
|
VAR_044860
|
Natural variant site
|
161 - 161
|
1
|
A -> V (in sporadic cancers; somatic mutation)
|
VAR_044864
|
Natural variant site
|
161 - 161
|
1
|
A -> P (in sporadic cancers; somatic mutation)
|
VAR_044862
|
Natural variant site
|
161 - 161
|
1
|
A -> G (in sporadic cancers; somatic mutation)
|
VAR_044861
|
Natural variant site
|
162 - 162
|
1
|
I -> M (in sporadic cancers; somatic mutation)
|
VAR_044866
|
Natural variant site
|
162 - 162
|
1
|
I -> N (in a breast cancer with no family history; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_044867
|
Natural variant site
|
162 - 162
|
1
|
I -> F (in sporadic cancers; somatic mutation)
|
VAR_044865
|
Natural variant site
|
162 - 162
|
1
|
I -> V (in sporadic cancers; somatic mutation)
|
VAR_005911
|
Natural variant site
|
162 - 162
|
1
|
I -> T (in sporadic cancers; somatic mutation)
|
VAR_044868
|
Natural variant site
|
162 - 162
|
1
|
I -> S (in sporadic cancers; somatic mutation)
|
VAR_005910
|
Natural variant site
|
163 - 163
|
1
|
Y -> D (in sporadic cancers; somatic mutation)
|
VAR_044869
|
Natural variant site
|
163 - 163
|
1
|
Y -> F (in a sporadic cancer; somatic mutation)
|
VAR_044870
|
Natural variant site
|
163 - 163
|
1
|
Y -> H (in sporadic cancers; somatic mutation)
|
VAR_005912
|
Natural variant site
|
163 - 163
|
1
|
Y -> N (in sporadic cancers; somatic mutation)
|
VAR_044871
|
Natural variant site
|
163 - 163
|
1
|
Y -> C (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_033035
|
Natural variant site
|
163 - 163
|
1
|
Y -> S (in sporadic cancers; somatic mutation)
|
VAR_044872
|
Natural variant site
|
164 - 164
|
1
|
K -> Q (in sporadic cancers; somatic mutation)
|
VAR_005914
|
Natural variant site
|
164 - 164
|
1
|
K -> M (in sporadic cancers; somatic mutation)
|
VAR_044874
|
Natural variant site
|
164 - 164
|
1
|
K -> R (in sporadic cancers; somatic mutation)
|
VAR_044875
|
Natural variant site
|
164 - 164
|
1
|
K -> N (in sporadic cancers; somatic mutation)
|
VAR_005913
|
Natural variant site
|
164 - 164
|
1
|
K -> T (in sporadic cancers; somatic mutation)
|
VAR_044876
|
Natural variant site
|
164 - 164
|
1
|
K -> E (in sporadic cancers; somatic mutation)
|
VAR_044873
|
Natural variant site
|
165 - 165
|
1
|
Q -> L (in sporadic cancers; somatic mutation)
|
VAR_005915
|
Natural variant site
|
165 - 165
|
1
|
Q -> R (in sporadic cancers; somatic mutation)
|
VAR_005916
|
Natural variant site
|
165 - 165
|
1
|
Q -> P (in sporadic cancers; somatic mutation)
|
VAR_044879
|
Natural variant site
|
165 - 165
|
1
|
Q -> H (in a sporadic cancer; somatic mutation)
|
VAR_044878
|
Natural variant site
|
165 - 165
|
1
|
Q -> E (in sporadic cancers; somatic mutation)
|
VAR_044877
|
Natural variant site
|
166 - 166
|
1
|
S -> T (in sporadic cancers; somatic mutation)
|
VAR_044883
|
Natural variant site
|
166 - 166
|
1
|
S -> L (in sporadic cancers; somatic mutation)
|
VAR_005917
|
Natural variant site
|
166 - 166
|
1
|
S -> G (in a sporadic cancer; somatic mutation)
|
VAR_044881
|
Natural variant site
|
166 - 166
|
1
|
S -> P (in sporadic cancers; somatic mutation)
|
VAR_044882
|
Natural variant site
|
166 - 166
|
1
|
S -> A (in sporadic cancers; somatic mutation)
|
VAR_044880
|
Natural variant site
|
167 - 168
|
2
|
QH -> YL (in a sporadic cancer; somatic mutation)
|
VAR_047164
|
Natural variant site
|
167 - 167
|
1
|
Q -> K (in LFS; germline mutation and in a sporadic cancer; somatic mutation)
|
VAR_044885
|
Natural variant site
|
167 - 167
|
1
|
Q -> L (in sporadic cancers; somatic mutation)
|
VAR_044886
|
Natural variant site
|
167 - 168
|
2
|
QH -> HD (in a sporadic cancer; somatic mutation)
|
VAR_047163
|
Natural variant site
|
167 - 167
|
1
|
Q -> H (in sporadic cancers; somatic mutation)
|
VAR_044884
|
Natural variant site
|
167 - 167
|
1
|
Q -> R (in sporadic cancers; somatic mutation)
|
VAR_044887
|
Natural variant site
|
168 - 168
|
1
|
H -> D (in sporadic cancers; somatic mutation)
|
VAR_044888
|
Natural variant site
|
168 - 168
|
1
|
H -> R (in sporadic cancers; somatic mutation)
|
VAR_005918
|
Natural variant site
|
168 - 168
|
1
|
H -> P (in sporadic cancers; somatic mutation)
|
VAR_044891
|
Natural variant site
|
168 - 168
|
1
|
H -> Q (in sporadic cancers; somatic mutation)
|
VAR_044892
|
Natural variant site
|
168 - 168
|
1
|
H -> V (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045801
|
Natural variant site
|
168 - 169
|
2
|
HM -> LI (in a sporadic cancer; somatic mutation)
|
VAR_047165
|
Natural variant site
|
168 - 168
|
1
|
H -> N (in sporadic cancers; somatic mutation)
|
VAR_044890
|
Natural variant site
|
168 - 168
|
1
|
H -> L (in sporadic cancers; somatic mutation)
|
VAR_044889
|
Natural variant site
|
168 - 168
|
1
|
H -> Y (in sporadic cancers; somatic mutation)
|
VAR_044893
|
Natural variant site
|
169 - 170
|
2
|
MT -> IS (in a sporadic cancer; somatic mutation)
|
VAR_047166
|
Natural variant site
|
169 - 169
|
1
|
M -> V (in sporadic cancers; somatic mutation)
|
VAR_044895
|
Natural variant site
|
169 - 169
|
1
|
M -> I (in sporadic cancers; somatic mutation)
|
VAR_005919
|
Natural variant site
|
169 - 169
|
1
|
M -> K (in sporadic cancers; somatic mutation)
|
VAR_044894
|
Natural variant site
|
169 - 169
|
1
|
M -> T (in sporadic cancers; somatic mutation)
|
VAR_005920
|
Natural variant site
|
170 - 170
|
1
|
T -> S (in sporadic cancers; somatic mutation)
|
VAR_005922
|
Natural variant site
|
170 - 170
|
1
|
T -> K (in a sporadic cancer; somatic mutation)
|
VAR_044897
|
Natural variant site
|
170 - 170
|
1
|
T -> P (in a sporadic cancer; somatic mutation)
|
VAR_044898
|
Natural variant site
|
170 - 170
|
1
|
T -> M (in sporadic cancers; somatic mutation)
|
VAR_005921
|
Natural variant site
|
170 - 170
|
1
|
T -> A (in sporadic cancers; somatic mutation)
|
VAR_044896
|
Natural variant site
|
171 - 171
|
1
|
E -> K (in sporadic cancers; somatic mutation)
|
VAR_044902
|
Natural variant site
|
171 - 171
|
1
|
E -> D (in sporadic cancers; somatic mutation)
|
VAR_044900
|
Natural variant site
|
171 - 171
|
1
|
E -> Q (in a sporadic cancer; somatic mutation)
|
VAR_044903
|
Natural variant site
|
171 - 171
|
1
|
E -> G (in sporadic cancers; somatic mutation)
|
VAR_044901
|
Natural variant site
|
171 - 171
|
1
|
E -> A (in a sporadic cancer; somatic mutation)
|
VAR_044899
|
Natural variant site
|
171 - 171
|
1
|
E -> V (in sporadic cancers; somatic mutation)
|
VAR_044904
|
Natural variant site
|
172 - 172
|
1
|
V -> A (in sporadic cancers; somatic mutation)
|
VAR_005923
|
Natural variant site
|
172 - 172
|
1
|
V -> G (in sporadic cancers; somatic mutation)
|
VAR_044907
|
Natural variant site
|
172 - 172
|
1
|
V -> F (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_044906
|
Natural variant site
|
172 - 172
|
1
|
V -> I (in sporadic cancers; somatic mutation)
|
VAR_044908
|
Natural variant site
|
172 - 172
|
1
|
V -> D (in sporadic cancers; somatic mutation)
|
VAR_044905
|
Natural variant site
|
173 - 173
|
1
|
V -> E (in sporadic cancers; somatic mutation)
|
VAR_005924
|
Natural variant site
|
173 - 173
|
1
|
V -> G (in sporadic cancers; somatic mutation)
|
VAR_044910
|
Natural variant site
|
173 - 173
|
1
|
V -> A (in sporadic cancers; somatic mutation)
|
VAR_044909
|
Natural variant site
|
173 - 173
|
1
|
V -> M (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_005926
|
Natural variant site
|
173 - 173
|
1
|
V -> W (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045802
|
Natural variant site
|
173 - 173
|
1
|
V -> L (in sporadic cancers; somatic mutation)
|
VAR_005925
|
Natural variant site
|
174 - 174
|
1
|
R -> W (in sporadic cancers; somatic mutation)
|
VAR_044915
|
Natural variant site
|
174 - 174
|
1
|
R -> T (in a sporadic cancer; somatic mutation)
|
VAR_044914
|
Natural variant site
|
174 - 174
|
1
|
R -> K (in sporadic cancers; somatic mutation)
|
VAR_005927
|
Natural variant site
|
174 - 174
|
1
|
R -> M (in sporadic cancers; somatic mutation)
|
VAR_044912
|
Natural variant site
|
174 - 174
|
1
|
R -> G (in LFS; germline mutation and in a sporadic cancer; somatic mutation)
|
VAR_044911
|
Natural variant site
|
174 - 174
|
1
|
R -> S (in sporadic cancers; somatic mutation)
|
VAR_044913
|
Natural variant site
|
175 - 175
|
1
|
R -> P (in sporadic cancers; somatic mutation)
|
VAR_005931
|
Natural variant site
|
175 - 175
|
1
|
R -> C (in sporadic cancers; somatic mutation)
|
VAR_005928
|
Natural variant site
|
175 - 175
|
1
|
R -> Q (in a sporadic cancer; somatic mutation)
|
VAR_044916
|
Natural variant site
|
175 - 175
|
1
|
R -> L (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_005930
|
Natural variant site
|
175 - 175
|
1
|
R -> H (in LFS; germline mutation and in sporadic cancers; somatic mutation; dbSNP:rs28934578)
|
VAR_005932
|
Natural variant site
|
175 - 175
|
1
|
R -> G (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_005929
|
Natural variant site
|
175 - 175
|
1
|
R -> S (in sporadic cancers; somatic mutation)
|
VAR_044917
|
Natural variant site
|
176 - 176
|
1
|
C -> W (in sporadic cancers; somatic mutation)
|
VAR_005934
|
Natural variant site
|
176 - 176
|
1
|
C -> R (in sporadic cancers; somatic mutation)
|
VAR_044919
|
Natural variant site
|
176 - 176
|
1
|
C -> F (in sporadic cancers; somatic mutation)
|
VAR_005933
|
Natural variant site
|
176 - 176
|
1
|
C -> Y (in sporadic cancers; somatic mutation)
|
VAR_044921
|
Natural variant site
|
176 - 176
|
1
|
C -> S (in sporadic cancers; somatic mutation)
|
VAR_044920
|
Natural variant site
|
176 - 176
|
1
|
C -> G (in sporadic cancers; somatic mutation)
|
VAR_044918
|
Natural variant site
|
176 - 177
|
2
|
CP -> FS (in a sporadic cancer; somatic mutation)
|
VAR_047167
|
Natural variant site
|
177 - 177
|
1
|
P -> T (in a sporadic cancer; somatic mutation)
|
VAR_044925
|
Natural variant site
|
177 - 177
|
1
|
P -> R (in sporadic cancers; somatic mutation)
|
VAR_036505
|
Natural variant site
|
177 - 177
|
1
|
P -> S (in sporadic cancers; somatic mutation)
|
VAR_044924
|
Natural variant site
|
177 - 177
|
1
|
P -> A (in a sporadic cancer; somatic mutation)
|
VAR_044922
|
Natural variant site
|
177 - 177
|
1
|
P -> L (in sporadic cancers; somatic mutation)
|
VAR_005935
|
Natural variant site
|
177 - 177
|
1
|
P -> H (in sporadic cancers; somatic mutation)
|
VAR_044923
|
Natural variant site
|
177 - 177
|
1
|
P -> F (in sporadic cancers; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045803
|
Natural variant site
|
177 - 177
|
1
|
P -> I (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045804
|
Natural variant site
|
178 - 178
|
1
|
H -> L (in a sporadic cancer; somatic mutation)
|
VAR_044927
|
Natural variant site
|
178 - 178
|
1
|
H -> Y (in sporadic cancers; somatic mutation)
|
VAR_044932
|
Natural variant site
|
178 - 178
|
1
|
H -> R (in sporadic cancers; somatic mutation)
|
VAR_044931
|
Natural variant site
|
178 - 178
|
1
|
H -> HPHP (in a Burkitt lymphoma)
|
VAR_005936
|
Natural variant site
|
178 - 178
|
1
|
H -> P (in sporadic cancers; somatic mutation)
|
VAR_044929
|
Natural variant site
|
178 - 178
|
1
|
H -> D (in sporadic cancers; somatic mutation)
|
VAR_044926
|
Natural variant site
|
178 - 178
|
1
|
H -> N (in sporadic cancers; somatic mutation)
|
VAR_044928
|
Natural variant site
|
178 - 179
|
2
|
HH -> QS (in a sporadic cancer; somatic mutation)
|
VAR_047168
|
Natural variant site
|
178 - 178
|
1
|
H -> Q (in sporadic cancers; somatic mutation)
|
VAR_044930
|
Natural variant site
|
179 - 179
|
1
|
H -> Y (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_044939
|
Natural variant site
|
179 - 179
|
1
|
H -> D (in sporadic cancers; somatic mutation)
|
VAR_044933
|
Natural variant site
|
179 - 179
|
1
|
H -> L (in sporadic cancers; somatic mutation)
|
VAR_044934
|
Natural variant site
|
179 - 179
|
1
|
H -> Q (in sporadic cancers; somatic mutation)
|
VAR_044937
|
Natural variant site
|
179 - 179
|
1
|
H -> R (in sporadic cancers; somatic mutation)
|
VAR_044938
|
Natural variant site
|
179 - 179
|
1
|
H -> P (in sporadic cancers; somatic mutation)
|
VAR_044936
|
Natural variant site
|
179 - 179
|
1
|
H -> N (in sporadic cancers; somatic mutation)
|
VAR_044935
|
Natural variant site
|
180 - 180
|
1
|
E -> A (in a sporadic cancer; somatic mutation)
|
VAR_044940
|
Natural variant site
|
180 - 180
|
1
|
E -> G (in a sporadic cancer; somatic mutation)
|
VAR_044942
|
Natural variant site
|
180 - 180
|
1
|
E -> K (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_044943
|
Natural variant site
|
180 - 180
|
1
|
E -> D (in sporadic cancers; somatic mutation)
|
VAR_044941
|
Natural variant site
|
180 - 180
|
1
|
E -> V (in a sporadic cancer; somatic mutation)
|
VAR_044945
|
Natural variant site
|
180 - 180
|
1
|
E -> Q (in sporadic cancers; somatic mutation)
|
VAR_044944
|
Natural variant site
|
181 - 181
|
1
|
R -> P (in a familial cancer not matching LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_044949
|
Natural variant site
|
181 - 181
|
1
|
R -> S (in sporadic cancers; somatic mutation)
|
VAR_044950
|
Natural variant site
|
181 - 181
|
1
|
R -> G (in sporadic cancers; somatic mutation)
|
VAR_044947
|
Natural variant site
|
181 - 181
|
1
|
R -> L (in a familial cancer not matching LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_005937
|
Natural variant site
|
181 - 181
|
1
|
R -> H (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_044948
|
Natural variant site
|
181 - 181
|
1
|
R -> C (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_044946
|
Natural variant site
|
182 - 182
|
1
|
C -> Y (in sporadic cancers; somatic mutation)
|
VAR_044952
|
Natural variant site
|
182 - 182
|
1
|
C -> S (in sporadic cancers; somatic mutation)
|
VAR_005938
|
Natural variant site
|
182 - 182
|
1
|
C -> R (in sporadic cancers; somatic mutation)
|
VAR_044951
|
Natural variant site
|
183 - 183
|
1
|
S -> P (in sporadic cancers; somatic mutation)
|
VAR_044954
|
Natural variant site
|
183 - 183
|
1
|
S -> L (in sporadic cancers; somatic mutation)
|
VAR_044953
|
Natural variant site
|
184 - 184
|
1
|
D -> V (in sporadic cancers; somatic mutation)
|
VAR_044957
|
Natural variant site
|
184 - 184
|
1
|
D -> G (in sporadic cancers; somatic mutation)
|
VAR_044955
|
Natural variant site
|
184 - 184
|
1
|
D -> H (in sporadic cancers; somatic mutation)
|
VAR_044956
|
Natural variant site
|
184 - 184
|
1
|
D -> Y (in sporadic cancers; somatic mutation)
|
VAR_005939
|
Natural variant site
|
184 - 184
|
1
|
D -> N (in sporadic cancers; somatic mutation)
|
VAR_047169
|
Natural variant site
|
185 - 185
|
1
|
S -> T (in a sporadic cancer; somatic mutation)
|
VAR_044963
|
Natural variant site
|
185 - 185
|
1
|
S -> G (in sporadic cancers; somatic mutation)
|
VAR_044959
|
Natural variant site
|
185 - 185
|
1
|
S -> C (in a sporadic cancer; somatic mutation)
|
VAR_044958
|
Natural variant site
|
185 - 185
|
1
|
S -> R (in sporadic cancers; somatic mutation)
|
VAR_044962
|
Natural variant site
|
185 - 185
|
1
|
S -> N (in a sporadic cancer; somatic mutation)
|
VAR_044961
|
Natural variant site
|
185 - 185
|
1
|
S -> I (in sporadic cancers; somatic mutation)
|
VAR_044960
|
Natural variant site
|
186 - 186
|
1
|
D -> Y (in a sporadic cancer; somatic mutation)
|
VAR_005940
|
Natural variant site
|
186 - 186
|
1
|
D -> H (in sporadic cancers; somatic mutation)
|
VAR_044966
|
Natural variant site
|
186 - 186
|
1
|
D -> V (in sporadic cancers; somatic mutation)
|
VAR_044968
|
Natural variant site
|
186 - 186
|
1
|
D -> N (in sporadic cancers; somatic mutation)
|
VAR_044967
|
Natural variant site
|
186 - 186
|
1
|
D -> G (in sporadic cancers; somatic mutation)
|
VAR_044965
|
Natural variant site
|
186 - 186
|
1
|
D -> E (in a sporadic cancer; somatic mutation)
|
VAR_044964
|
Natural variant site
|
187 - 187
|
1
|
G -> R (in sporadic cancers; somatic mutation)
|
VAR_044970
|
Natural variant site
|
187 - 187
|
1
|
G -> S (in sporadic cancers; somatic mutation)
|
VAR_005942
|
Natural variant site
|
187 - 187
|
1
|
G -> N (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045805
|
Natural variant site
|
187 - 187
|
1
|
G -> C (in sporadic cancers; somatic mutation)
|
VAR_005941
|
Natural variant site
|
187 - 187
|
1
|
G -> V (in sporadic cancers; somatic mutation)
|
VAR_044971
|
Natural variant site
|
187 - 187
|
1
|
G -> D (in sporadic cancers; somatic mutation)
|
VAR_044969
|
Natural variant site
|
188 - 188
|
1
|
L -> V (in sporadic cancers; somatic mutation)
|
VAR_044973
|
Natural variant site
|
188 - 188
|
1
|
L -> P (in a sporadic cancer; somatic mutation)
|
VAR_044972
|
Natural variant site
|
189 - 189
|
1
|
A -> P (in sporadic cancers; somatic mutation)
|
VAR_005943
|
Natural variant site
|
189 - 189
|
1
|
A -> D (in a sporadic cancer; somatic mutation)
|
VAR_044974
|
Natural variant site
|
189 - 189
|
1
|
A -> T (in sporadic cancers; somatic mutation)
|
VAR_044977
|
Natural variant site
|
189 - 189
|
1
|
A -> V (in a familial cancer not matching LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_044978
|
Natural variant site
|
189 - 189
|
1
|
A -> S (in a sporadic cancer; somatic mutation)
|
VAR_044976
|
Natural variant site
|
189 - 189
|
1
|
A -> G (in sporadic cancers; somatic mutation)
|
VAR_044975
|
Natural variant site
|
190 - 190
|
1
|
P -> H (in a sporadic cancer; somatic mutation)
|
VAR_044980
|
Natural variant site
|
190 - 190
|
1
|
P -> L (in sporadic cancers; somatic mutation)
|
VAR_005944
|
Natural variant site
|
190 - 190
|
1
|
P -> T (in sporadic cancers; somatic mutation)
|
VAR_044983
|
Natural variant site
|
190 - 190
|
1
|
P -> S (in sporadic cancers; somatic mutation)
|
VAR_044982
|
Natural variant site
|
190 - 190
|
1
|
P -> A (in sporadic cancers; somatic mutation)
|
VAR_044979
|
Natural variant site
|
190 - 190
|
1
|
P -> R (in sporadic cancers; somatic mutation)
|
VAR_044981
|
Natural variant site
|
191 - 191
|
1
|
P -> H (in sporadic cancers; somatic mutation)
|
VAR_044984
|
Natural variant site
|
191 - 191
|
1
|
P -> L (in sporadic cancers; somatic mutation)
|
VAR_044985
|
Natural variant site
|
191 - 191
|
1
|
P -> S (in sporadic cancers; somatic mutation)
|
VAR_044987
|
Natural variant site
|
191 - 191
|
1
|
P -> R (in sporadic cancers; somatic mutation)
|
VAR_044986
|
Natural variant site
|
191 - 191
|
1
|
P -> T (in sporadic cancers; somatic mutation)
|
VAR_005945
|
Natural variant site
|
192 - 193
|
2
|
QH -> HN (in a sporadic cancer; somatic mutation)
|
VAR_047170
|
Natural variant site
|
192 - 193
|
2
|
QH -> HY (in a sporadic cancer; somatic mutation)
|
VAR_047171
|
Natural variant site
|
192 - 192
|
1
|
Q -> R (in sporadic cancers; somatic mutation)
|
VAR_005946
|
Natural variant site
|
192 - 192
|
1
|
Q -> L (in sporadic cancers; somatic mutation)
|
VAR_044990
|
Natural variant site
|
192 - 192
|
1
|
Q -> K (in a sporadic cancer; somatic mutation)
|
VAR_044989
|
Natural variant site
|
192 - 192
|
1
|
Q -> P (in sporadic cancers; somatic mutation)
|
VAR_044991
|
Natural variant site
|
192 - 192
|
1
|
Q -> H (in sporadic cancers; somatic mutation)
|
VAR_044988
|
Natural variant site
|
193 - 193
|
1
|
H -> P (in sporadic cancers; somatic mutation)
|
VAR_044994
|
Natural variant site
|
193 - 193
|
1
|
H -> Y (in sporadic cancers; somatic mutation)
|
VAR_044996
|
Natural variant site
|
193 - 193
|
1
|
H -> Q (in sporadic cancers; somatic mutation)
|
VAR_044995
|
Natural variant site
|
193 - 193
|
1
|
H -> D (in sporadic cancers; somatic mutation)
|
VAR_005947
|
Natural variant site
|
193 - 193
|
1
|
H -> L (in sporadic cancers; somatic mutation)
|
VAR_044992
|
Natural variant site
|
193 - 193
|
1
|
H -> R (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_005948
|
Natural variant site
|
193 - 193
|
1
|
H -> N (in sporadic cancers; somatic mutation)
|
VAR_044993
|
Natural variant site
|
194 - 194
|
1
|
L -> P (in sporadic cancers; somatic mutation)
|
VAR_005949
|
Natural variant site
|
194 - 194
|
1
|
L -> I (in sporadic cancers; somatic mutation)
|
VAR_044999
|
Natural variant site
|
194 - 194
|
1
|
L -> V (in sporadic cancers; somatic mutation)
|
VAR_045000
|
Natural variant site
|
194 - 194
|
1
|
L -> F (in sporadic cancers; somatic mutation)
|
VAR_044997
|
Natural variant site
|
194 - 194
|
1
|
L -> R (in sporadic cancers; somatic mutation)
|
VAR_005950
|
Natural variant site
|
194 - 194
|
1
|
L -> H (in sporadic cancers; somatic mutation)
|
VAR_044998
|
Natural variant site
|
195 - 195
|
1
|
I -> S (in sporadic cancers; somatic mutation)
|
VAR_045003
|
Natural variant site
|
195 - 195
|
1
|
I -> N (in sporadic cancers; somatic mutation)
|
VAR_045002
|
Natural variant site
|
195 - 195
|
1
|
I -> Y (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045806
|
Natural variant site
|
195 - 195
|
1
|
I -> F (in sporadic cancers; somatic mutation)
|
VAR_045001
|
Natural variant site
|
195 - 195
|
1
|
I -> T (in sporadic cancers; somatic mutation)
|
VAR_005951
|
Natural variant site
|
195 - 195
|
1
|
I -> L (in a sporadic cancer; somatic mutation)
|
VAR_047172
|
Natural variant site
|
195 - 195
|
1
|
I -> V (in a sporadic cancer; somatic mutation)
|
VAR_045004
|
Natural variant site
|
196 - 196
|
1
|
R -> G (in sporadic cancers; somatic mutation)
|
VAR_045005
|
Natural variant site
|
196 - 196
|
1
|
R -> Q (in sporadic cancers; somatic mutation)
|
VAR_045008
|
Natural variant site
|
196 - 196
|
1
|
R -> S (in a sporadic cancer; somatic mutation)
|
VAR_045009
|
Natural variant site
|
196 - 196
|
1
|
R -> P (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_045007
|
Natural variant site
|
196 - 196
|
1
|
R -> L (in sporadic cancers; somatic mutation)
|
VAR_045006
|
Natural variant site
|
197 - 197
|
1
|
V -> G (in sporadic cancers; somatic mutation)
|
VAR_045011
|
Natural variant site
|
197 - 197
|
1
|
V -> M (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_045013
|
Natural variant site
|
197 - 197
|
1
|
V -> L (in sporadic cancers; somatic mutation)
|
VAR_045012
|
Natural variant site
|
197 - 197
|
1
|
V -> E (in a familial cancer not matching LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_045010
|
Natural variant site
|
198 - 198
|
1
|
E -> V (in a sporadic cancer; somatic mutation)
|
VAR_045017
|
Natural variant site
|
198 - 198
|
1
|
E -> Q (in sporadic cancers; somatic mutation)
|
VAR_045016
|
Natural variant site
|
198 - 198
|
1
|
E -> D (in a sporadic cancer; somatic mutation)
|
VAR_045014
|
Natural variant site
|
198 - 198
|
1
|
E -> K (in sporadic cancers; somatic mutation)
|
VAR_005952
|
Natural variant site
|
198 - 198
|
1
|
E -> G (in sporadic cancers; somatic mutation)
|
VAR_045015
|
Natural variant site
|
199 - 199
|
1
|
G -> R (in sporadic cancers; somatic mutation)
|
VAR_045020
|
Natural variant site
|
199 - 199
|
1
|
G -> A (in a sporadic cancer; somatic mutation)
|
VAR_045018
|
Natural variant site
|
199 - 199
|
1
|
G -> E (in sporadic cancers; somatic mutation)
|
VAR_045019
|
Natural variant site
|
199 - 199
|
1
|
G -> V (in sporadic cancers; somatic mutation)
|
VAR_045021
|
Natural variant site
|
200 - 200
|
1
|
N -> D (in sporadic cancers; somatic mutation)
|
VAR_045022
|
Natural variant site
|
200 - 200
|
1
|
N -> I (in sporadic cancers; somatic mutation)
|
VAR_045023
|
Natural variant site
|
200 - 200
|
1
|
N -> S (in sporadic cancers; somatic mutation)
|
VAR_045025
|
Natural variant site
|
200 - 200
|
1
|
N -> T (in a sporadic cancer; somatic mutation)
|
VAR_045026
|
Natural variant site
|
200 - 200
|
1
|
N -> P (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045807
|
Natural variant site
|
200 - 200
|
1
|
N -> K (in a sporadic cancer; somatic mutation)
|
VAR_045024
|
Natural variant site
|
201 - 201
|
1
|
L -> F (in sporadic cancers; somatic mutation)
|
VAR_045027
|
Natural variant site
|
201 - 201
|
1
|
L -> S (in a sporadic cancer; somatic mutation)
|
VAR_045029
|
Natural variant site
|
201 - 202
|
2
|
LR -> FC (in a sporadic cancer; somatic mutation)
|
VAR_047173
|
Natural variant site
|
201 - 201
|
1
|
L -> P (in a sporadic cancer; somatic mutation)
|
VAR_045028
|
Natural variant site
|
202 - 202
|
1
|
R -> G (in sporadic cancers; somatic mutation)
|
VAR_045031
|
Natural variant site
|
202 - 202
|
1
|
R -> L (in sporadic cancers; somatic mutation)
|
VAR_045033
|
Natural variant site
|
202 - 202
|
1
|
R -> S (in sporadic cancers; somatic mutation)
|
VAR_045035
|
Natural variant site
|
202 - 202
|
1
|
R -> H (in sporadic cancers; somatic mutation)
|
VAR_045032
|
Natural variant site
|
202 - 202
|
1
|
R -> P (in sporadic cancers; somatic mutation)
|
VAR_045034
|
Natural variant site
|
202 - 202
|
1
|
R -> C (in sporadic cancers; somatic mutation)
|
VAR_045030
|
Natural variant site
|
203 - 203
|
1
|
V -> W (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045808
|
Natural variant site
|
203 - 203
|
1
|
V -> A (in sporadic cancers; somatic mutation)
|
VAR_045036
|
Natural variant site
|
203 - 203
|
1
|
V -> E (in sporadic cancers; somatic mutation)
|
VAR_045037
|
Natural variant site
|
203 - 204
|
2
|
VE -> LV (in a sporadic cancer; somatic mutation)
|
VAR_047174
|
Natural variant site
|
203 - 203
|
1
|
V -> M (in sporadic cancers; somatic mutation)
|
VAR_045039
|
Natural variant site
|
203 - 203
|
1
|
V -> L (in sporadic cancers; somatic mutation)
|
VAR_045038
|
Natural variant site
|
204 - 204
|
1
|
E -> A (in sporadic cancers; somatic mutation)
|
VAR_045040
|
Natural variant site
|
204 - 204
|
1
|
E -> D (in sporadic cancers; somatic mutation)
|
VAR_045041
|
Natural variant site
|
204 - 204
|
1
|
E -> G (in sporadic cancers; somatic mutation)
|
VAR_045042
|
Natural variant site
|
204 - 204
|
1
|
E -> V (in a sporadic cancer; somatic mutation)
|
VAR_045045
|
Natural variant site
|
204 - 204
|
1
|
E -> K (in sporadic cancers; somatic mutation)
|
VAR_045043
|
Natural variant site
|
204 - 204
|
1
|
E -> Q (in a sporadic cancer; somatic mutation)
|
VAR_045044
|
Natural variant site
|
205 - 205
|
1
|
Y -> C (in sporadic cancers; somatic mutation)
|
VAR_005953
|
Natural variant site
|
205 - 205
|
1
|
Y -> N (in sporadic cancers; somatic mutation)
|
VAR_045047
|
Natural variant site
|
205 - 205
|
1
|
Y -> F (in sporadic cancers; somatic mutation)
|
VAR_047175
|
Natural variant site
|
205 - 205
|
1
|
Y -> S (in sporadic cancers; somatic mutation)
|
VAR_045048
|
Natural variant site
|
205 - 205
|
1
|
Y -> H (in sporadic cancers; somatic mutation)
|
VAR_045046
|
Natural variant site
|
205 - 205
|
1
|
Y -> D (in sporadic cancers; somatic mutation)
|
VAR_005954
|
Natural variant site
|
206 - 206
|
1
|
L -> M (in a sporadic cancer; somatic mutation)
|
VAR_045050
|
Natural variant site
|
206 - 206
|
1
|
L -> F (in a sporadic cancer; somatic mutation)
|
VAR_045049
|
Natural variant site
|
207 - 207
|
1
|
D -> Y (in a sporadic cancer; somatic mutation)
|
VAR_045056
|
Natural variant site
|
207 - 208
|
2
|
DD -> EY (in a sporadic cancer; somatic mutation)
|
VAR_047176
|
Natural variant site
|
207 - 207
|
1
|
D -> N (in sporadic cancers; somatic mutation)
|
VAR_045054
|
Natural variant site
|
207 - 207
|
1
|
D -> E (in sporadic cancers; somatic mutation)
|
VAR_045051
|
Natural variant site
|
207 - 207
|
1
|
D -> H (in sporadic cancers; somatic mutation)
|
VAR_045053
|
Natural variant site
|
207 - 207
|
1
|
D -> G (in sporadic cancers; somatic mutation)
|
VAR_045052
|
Natural variant site
|
207 - 207
|
1
|
D -> V (in a sporadic cancer; somatic mutation)
|
VAR_045055
|
Natural variant site
|
208 - 208
|
1
|
D -> G (in sporadic cancers; somatic mutation)
|
VAR_045058
|
Natural variant site
|
208 - 208
|
1
|
D -> I (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045809
|
Natural variant site
|
208 - 208
|
1
|
D -> N (in sporadic cancers; somatic mutation)
|
VAR_045060
|
Natural variant site
|
208 - 208
|
1
|
D -> E (in sporadic cancers; somatic mutation)
|
VAR_045057
|
Natural variant site
|
208 - 208
|
1
|
D -> H (in a sporadic cancer; somatic mutation)
|
VAR_045059
|
Natural variant site
|
208 - 208
|
1
|
D -> Y (in a sporadic cancer; somatic mutation)
|
VAR_045062
|
Natural variant site
|
208 - 208
|
1
|
D -> V (in sporadic cancers; somatic mutation)
|
VAR_045061
|
Natural variant site
|
209 - 209
|
1
|
R -> S (in a sporadic cancer; somatic mutation)
|
VAR_045065
|
Natural variant site
|
209 - 209
|
1
|
R -> I (in sporadic cancers; somatic mutation)
|
VAR_045063
|
Natural variant site
|
209 - 209
|
1
|
R -> T (in sporadic cancers; somatic mutation)
|
VAR_045066
|
Natural variant site
|
209 - 209
|
1
|
R -> K (in sporadic cancers; somatic mutation)
|
VAR_045064
|
Natural variant site
|
210 - 210
|
1
|
N -> D (in sporadic cancers; somatic mutation)
|
VAR_045067
|
Natural variant site
|
210 - 210
|
1
|
N -> I (in a sporadic cancer; somatic mutation)
|
VAR_045069
|
Natural variant site
|
210 - 210
|
1
|
N -> T (in a sporadic cancer; somatic mutation)
|
VAR_045072
|
Natural variant site
|
210 - 210
|
1
|
N -> Y (in a familial cancer not matching LFS; germline mutation)
|
VAR_045073
|
Natural variant site
|
210 - 210
|
1
|
N -> S (in sporadic cancers; somatic mutation)
|
VAR_045071
|
Natural variant site
|
210 - 210
|
1
|
N -> K (in a sporadic cancer; somatic mutation)
|
VAR_045070
|
Natural variant site
|
210 - 210
|
1
|
N -> H (in sporadic cancers; somatic mutation)
|
VAR_045068
|
Natural variant site
|
211 - 211
|
1
|
T -> P (in a sporadic cancer; somatic mutation)
|
VAR_045077
|
Natural variant site
|
211 - 211
|
1
|
T -> A (in sporadic cancers; somatic mutation)
|
VAR_045074
|
Natural variant site
|
211 - 211
|
1
|
T -> I (in sporadic cancers; somatic mutation)
|
VAR_045075
|
Natural variant site
|
211 - 211
|
1
|
T -> N (in sporadic cancers; somatic mutation)
|
VAR_045076
|
Natural variant site
|
211 - 211
|
1
|
T -> S (in sporadic cancers; somatic mutation)
|
VAR_045078
|
Natural variant site
|
212 - 212
|
1
|
F -> Y (in sporadic cancers; somatic mutation)
|
VAR_045083
|
Natural variant site
|
212 - 212
|
1
|
F -> L (in sporadic cancers; somatic mutation)
|
VAR_045080
|
Natural variant site
|
212 - 212
|
1
|
F -> V (in a sporadic cancer; somatic mutation)
|
VAR_045082
|
Natural variant site
|
212 - 212
|
1
|
F -> I (in sporadic cancers; somatic mutation)
|
VAR_045079
|
Natural variant site
|
212 - 212
|
1
|
F -> S (in sporadic cancers; somatic mutation)
|
VAR_045081
|
Natural variant site
|
213 - 213
|
1
|
R -> L (in sporadic cancers; somatic mutation)
|
VAR_045085
|
Natural variant site
|
213 - 213
|
1
|
R -> Q (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_005955
|
Natural variant site
|
213 - 213
|
1
|
R -> W (in sporadic cancers; somatic mutation)
|
VAR_045086
|
Natural variant site
|
213 - 213
|
1
|
R -> G (in sporadic cancers; somatic mutation)
|
VAR_045084
|
Natural variant site
|
213 - 213
|
1
|
R -> P (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_036506
|
Natural variant site
|
214 - 214
|
1
|
H -> Y (in sporadic cancers; somatic mutation)
|
VAR_045090
|
Natural variant site
|
214 - 214
|
1
|
H -> Q (in sporadic cancers; somatic mutation)
|
VAR_047177
|
Natural variant site
|
214 - 214
|
1
|
H -> D (in sporadic cancers; somatic mutation)
|
VAR_045087
|
Natural variant site
|
214 - 214
|
1
|
H -> P (in a sporadic cancer; somatic mutation)
|
VAR_045088
|
Natural variant site
|
214 - 214
|
1
|
H -> R (in sporadic cancers; somatic mutation)
|
VAR_045089
|
Natural variant site
|
215 - 215
|
1
|
S -> C (in sporadic cancers; somatic mutation)
|
VAR_045091
|
Natural variant site
|
215 - 215
|
1
|
S -> I (in sporadic cancers; somatic mutation)
|
VAR_045093
|
Natural variant site
|
215 - 215
|
1
|
S -> N (in sporadic cancers; somatic mutation)
|
VAR_045094
|
Natural variant site
|
215 - 215
|
1
|
S -> R (in sporadic cancers; somatic mutation)
|
VAR_045095
|
Natural variant site
|
215 - 215
|
1
|
S -> T (in sporadic cancers; somatic mutation)
|
VAR_045096
|
Natural variant site
|
215 - 215
|
1
|
S -> G (in sporadic cancers; somatic mutation)
|
VAR_045092
|
Natural variant site
|
215 - 215
|
1
|
S -> K (in sporadic cancers; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045810
|
Natural variant site
|
216 - 216
|
1
|
V -> L (in sporadic cancers; somatic mutation)
|
VAR_045100
|
Natural variant site
|
216 - 216
|
1
|
V -> M (in sporadic cancers; somatic mutation)
|
VAR_005956
|
Natural variant site
|
216 - 216
|
1
|
V -> A (in sporadic cancers; somatic mutation)
|
VAR_045097
|
Natural variant site
|
216 - 216
|
1
|
V -> E (in sporadic cancers; somatic mutation)
|
VAR_045098
|
Natural variant site
|
216 - 216
|
1
|
V -> G (in sporadic cancers; somatic mutation)
|
VAR_045099
|
Natural variant site
|
216 - 216
|
1
|
V -> W (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045811
|
Natural variant site
|
217 - 217
|
1
|
V -> G (in sporadic cancers; somatic mutation)
|
VAR_045103
|
Natural variant site
|
217 - 217
|
1
|
V -> M (in dbSNP:rs35163653)
|
VAR_047178
|
Natural variant site
|
217 - 217
|
1
|
V -> A (in sporadic cancers; somatic mutation)
|
VAR_045101
|
Natural variant site
|
217 - 217
|
1
|
V -> E (in sporadic cancers; somatic mutation)
|
VAR_045102
|
Natural variant site
|
217 - 217
|
1
|
V -> I (in a sporadic cancer; somatic mutation)
|
VAR_045104
|
Natural variant site
|
217 - 217
|
1
|
V -> L (in sporadic cancers; somatic mutation)
|
VAR_045105
|
Natural variant site
|
218 - 218
|
1
|
V -> A (in sporadic cancers; somatic mutation)
|
VAR_045106
|
Natural variant site
|
218 - 218
|
1
|
V -> G (in sporadic cancers; somatic mutation)
|
VAR_045108
|
Natural variant site
|
218 - 218
|
1
|
V -> E (in sporadic cancers; somatic mutation)
|
VAR_045107
|
Natural variant site
|
218 - 218
|
1
|
V -> L (in sporadic cancers; somatic mutation)
|
VAR_045109
|
Natural variant site
|
218 - 218
|
1
|
V -> M (in sporadic cancers; somatic mutation)
|
VAR_045110
|
Natural variant site
|
219 - 219
|
1
|
P -> R (in a sporadic cancer; somatic mutation)
|
VAR_045113
|
Natural variant site
|
219 - 219
|
1
|
P -> S (in a familial cancer not matching LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_045114
|
Natural variant site
|
219 - 219
|
1
|
P -> H (in a sporadic cancer; somatic mutation)
|
VAR_045111
|
Natural variant site
|
219 - 219
|
1
|
P -> C (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045812
|
Natural variant site
|
219 - 219
|
1
|
P -> L (in sporadic cancers; somatic mutation)
|
VAR_045112
|
Natural variant site
|
219 - 219
|
1
|
P -> T (in sporadic cancers; somatic mutation)
|
VAR_045115
|
Natural variant site
|
220 - 220
|
1
|
Y -> C (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_005957
|
Natural variant site
|
220 - 220
|
1
|
Y -> D (in sporadic cancers; somatic mutation)
|
VAR_045116
|
Natural variant site
|
220 - 220
|
1
|
Y -> F (in a sporadic cancer; somatic mutation)
|
VAR_045117
|
Natural variant site
|
220 - 220
|
1
|
Y -> H (in sporadic cancers; somatic mutation)
|
VAR_005958
|
Natural variant site
|
220 - 220
|
1
|
Y -> S (in a brain tumor with no family history; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_005959
|
Natural variant site
|
220 - 220
|
1
|
Y -> N (in sporadic cancers; somatic mutation)
|
VAR_045118
|
Natural variant site
|
221 - 221
|
1
|
E -> K (in sporadic cancers; somatic mutation)
|
VAR_045122
|
Natural variant site
|
221 - 221
|
1
|
E -> A (in sporadic cancers; somatic mutation)
|
VAR_045119
|
Natural variant site
|
221 - 221
|
1
|
E -> D (in sporadic cancers; somatic mutation)
|
VAR_045120
|
Natural variant site
|
221 - 221
|
1
|
E -> G (in sporadic cancers; somatic mutation)
|
VAR_045121
|
Natural variant site
|
221 - 221
|
1
|
E -> Q (in sporadic cancers; somatic mutation)
|
VAR_045123
|
Natural variant site
|
222 - 222
|
1
|
P -> R (in a sporadic cancer; somatic mutation)
|
VAR_045127
|
Natural variant site
|
222 - 222
|
1
|
P -> L (in sporadic cancers; somatic mutation)
|
VAR_045125
|
Natural variant site
|
222 - 222
|
1
|
P -> A (in a sporadic cancer; somatic mutation)
|
VAR_045124
|
Natural variant site
|
222 - 222
|
1
|
P -> T (in sporadic cancers; somatic mutation)
|
VAR_045129
|
Natural variant site
|
222 - 222
|
1
|
P -> S (in sporadic cancers; somatic mutation)
|
VAR_045128
|
Natural variant site
|
222 - 222
|
1
|
P -> Q (in sporadic cancers; somatic mutation)
|
VAR_045126
|
Natural variant site
|
223 - 223
|
1
|
P -> H (in sporadic cancers; somatic mutation)
|
VAR_045130
|
Natural variant site
|
223 - 223
|
1
|
P -> S (in a sporadic cancer; somatic mutation)
|
VAR_045133
|
Natural variant site
|
223 - 223
|
1
|
P -> A (in a sporadic cancer; somatic mutation)
|
VAR_047179
|
Natural variant site
|
223 - 223
|
1
|
P -> T (in a sporadic cancer; somatic mutation)
|
VAR_045134
|
Natural variant site
|
223 - 223
|
1
|
P -> R (in a sporadic cancer; somatic mutation)
|
VAR_045132
|
Natural variant site
|
223 - 223
|
1
|
P -> L (in sporadic cancers; somatic mutation)
|
VAR_045131
|
Natural variant site
|
224 - 224
|
1
|
E -> V (in a sporadic cancer; somatic mutation)
|
VAR_045138
|
Natural variant site
|
224 - 224
|
1
|
E -> D (in sporadic cancers; somatic mutation)
|
VAR_045135
|
Natural variant site
|
224 - 224
|
1
|
E -> G (in sporadic cancers; somatic mutation)
|
VAR_045136
|
Natural variant site
|
224 - 224
|
1
|
E -> K (in sporadic cancers; somatic mutation)
|
VAR_045137
|
Natural variant site
|
225 - 225
|
1
|
V -> G (in a sporadic cancer; somatic mutation)
|
VAR_045142
|
Natural variant site
|
225 - 225
|
1
|
V -> I (in sporadic cancers; somatic mutation)
|
VAR_045143
|
Natural variant site
|
225 - 225
|
1
|
V -> A (in sporadic cancers; somatic mutation)
|
VAR_045139
|
Natural variant site
|
225 - 225
|
1
|
V -> F (in sporadic cancers; somatic mutation)
|
VAR_045141
|
Natural variant site
|
225 - 225
|
1
|
V -> L (in a sporadic cancer; somatic mutation)
|
VAR_045144
|
Natural variant site
|
225 - 225
|
1
|
V -> D (in a sporadic cancer; somatic mutation)
|
VAR_045140
|
Natural variant site
|
226 - 226
|
1
|
G -> A (in sporadic cancers; somatic mutation)
|
VAR_045145
|
Natural variant site
|
226 - 226
|
1
|
G -> N (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045844
|
Natural variant site
|
226 - 226
|
1
|
G -> V (in sporadic cancers; somatic mutation)
|
VAR_045147
|
Natural variant site
|
226 - 226
|
1
|
G -> D (in sporadic cancers; somatic mutation)
|
VAR_047180
|
Natural variant site
|
226 - 226
|
1
|
G -> S (in sporadic cancers; somatic mutation)
|
VAR_045146
|
Natural variant site
|
227 - 227
|
1
|
S -> P (in a sporadic cancer; somatic mutation)
|
VAR_045150
|
Natural variant site
|
227 - 227
|
1
|
S -> C (in sporadic cancers; somatic mutation)
|
VAR_045148
|
Natural variant site
|
227 - 227
|
1
|
S -> F (in sporadic cancers; somatic mutation)
|
VAR_045149
|
Natural variant site
|
227 - 227
|
1
|
S -> T (in LFS; germline mutation and in a sporadic cancer; somatic mutation)
|
VAR_045151
|
Natural variant site
|
228 - 228
|
1
|
D -> Y (in sporadic cancers; somatic mutation)
|
VAR_045157
|
Natural variant site
|
228 - 228
|
1
|
D -> P (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045845
|
Natural variant site
|
228 - 228
|
1
|
D -> A (in sporadic cancers; somatic mutation)
|
VAR_045152
|
Natural variant site
|
228 - 228
|
1
|
D -> V (in sporadic cancers; somatic mutation)
|
VAR_045156
|
Natural variant site
|
228 - 228
|
1
|
D -> E (in sporadic cancers; somatic mutation)
|
VAR_005960
|
Natural variant site
|
228 - 228
|
1
|
D -> N (in sporadic cancers; somatic mutation)
|
VAR_045155
|
Natural variant site
|
228 - 228
|
1
|
D -> H (in sporadic cancers; somatic mutation)
|
VAR_045154
|
Natural variant site
|
228 - 228
|
1
|
D -> G (in sporadic cancers; somatic mutation)
|
VAR_045153
|
Natural variant site
|
229 - 229
|
1
|
C -> G (in a sporadic cancer; somatic mutation)
|
VAR_045158
|
Natural variant site
|
229 - 229
|
1
|
C -> S (in sporadic cancers; somatic mutation)
|
VAR_045160
|
Natural variant site
|
229 - 229
|
1
|
C -> R (in sporadic cancers; somatic mutation)
|
VAR_045159
|
Natural variant site
|
229 - 229
|
1
|
C -> Y (in sporadic cancers; somatic mutation)
|
VAR_045161
|
Natural variant site
|
229 - 229
|
1
|
C -> N (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045846
|
Natural variant site
|
230 - 230
|
1
|
T -> P (in sporadic cancers; somatic mutation)
|
VAR_045164
|
Natural variant site
|
230 - 230
|
1
|
T -> I (in sporadic cancers; somatic mutation)
|
VAR_005961
|
Natural variant site
|
230 - 230
|
1
|
T -> A (in sporadic cancers; somatic mutation)
|
VAR_045162
|
Natural variant site
|
230 - 230
|
1
|
T -> N (in sporadic cancers; somatic mutation)
|
VAR_045163
|
Natural variant site
|
230 - 230
|
1
|
T -> S (in sporadic cancers; somatic mutation)
|
VAR_045165
|
Natural variant site
|
231 - 231
|
1
|
T -> N (in sporadic cancers; somatic mutation)
|
VAR_045168
|
Natural variant site
|
231 - 231
|
1
|
T -> I (in sporadic cancers; somatic mutation)
|
VAR_045167
|
Natural variant site
|
231 - 231
|
1
|
T -> A (in sporadic cancers; somatic mutation)
|
VAR_045166
|
Natural variant site
|
231 - 231
|
1
|
T -> S (in sporadic cancers; somatic mutation)
|
VAR_045169
|
Natural variant site
|
232 - 232
|
1
|
I -> V (in sporadic cancers; somatic mutation)
|
VAR_045174
|
Natural variant site
|
232 - 232
|
1
|
I -> T (in sporadic cancers; somatic mutation)
|
VAR_005962
|
Natural variant site
|
232 - 232
|
1
|
I -> N (in sporadic cancers; somatic mutation)
|
VAR_045172
|
Natural variant site
|
232 - 232
|
1
|
I -> S (in sporadic cancers; somatic mutation)
|
VAR_045173
|
Natural variant site
|
232 - 232
|
1
|
I -> F (in sporadic cancers; somatic mutation)
|
VAR_045170
|
Natural variant site
|
232 - 232
|
1
|
I -> L (in sporadic cancers; somatic mutation)
|
VAR_045171
|
Natural variant site
|
233 - 233
|
1
|
H -> P (in a sporadic cancer; somatic mutation)
|
VAR_045177
|
Natural variant site
|
233 - 233
|
1
|
H -> L (in sporadic cancers; somatic mutation)
|
VAR_045176
|
Natural variant site
|
233 - 233
|
1
|
H -> R (in sporadic cancers; somatic mutation)
|
VAR_047181
|
Natural variant site
|
233 - 233
|
1
|
H -> Y (in sporadic cancers; somatic mutation)
|
VAR_045179
|
Natural variant site
|
233 - 233
|
1
|
H -> D (in LFS; germline mutation and in a sporadic cancer; somatic mutation)
|
VAR_045175
|
Natural variant site
|
233 - 233
|
1
|
H -> Q (in sporadic cancers; somatic mutation)
|
VAR_045178
|
Natural variant site
|
234 - 234
|
1
|
Y -> S (in sporadic cancers; somatic mutation)
|
VAR_045183
|
Natural variant site
|
234 - 234
|
1
|
Y -> K (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045847
|
Natural variant site
|
234 - 234
|
1
|
Y -> C (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_005963
|
Natural variant site
|
234 - 234
|
1
|
Y -> D (in sporadic cancers; somatic mutation)
|
VAR_045180
|
Natural variant site
|
234 - 234
|
1
|
Y -> F (in a sporadic cancer; somatic mutation)
|
VAR_045181
|
Natural variant site
|
234 - 234
|
1
|
Y -> N (in sporadic cancers; somatic mutation)
|
VAR_045182
|
Natural variant site
|
234 - 234
|
1
|
Y -> Q (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045848
|
Natural variant site
|
234 - 234
|
1
|
Y -> H (in sporadic cancers; somatic mutation)
|
VAR_005964
|
Natural variant site
|
235 - 235
|
1
|
N -> M (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045849
|
Natural variant site
|
235 - 235
|
1
|
N -> T (in sporadic cancers; somatic mutation)
|
VAR_045187
|
Natural variant site
|
235 - 235
|
1
|
N -> D (in an adrenocortical carcinoma with no family history; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_047182
|
Natural variant site
|
235 - 235
|
1
|
N -> S (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_045186
|
Natural variant site
|
235 - 235
|
1
|
N -> Y (in sporadic cancers; somatic mutation)
|
VAR_045188
|
Natural variant site
|
235 - 235
|
1
|
N -> I (in sporadic cancers; somatic mutation)
|
VAR_045185
|
Natural variant site
|
235 - 235
|
1
|
N -> H (in a sporadic cancer; somatic mutation)
|
VAR_045184
|
Natural variant site
|
236 - 236
|
1
|
Y -> D (in sporadic cancers; somatic mutation)
|
VAR_045190
|
Natural variant site
|
236 - 236
|
1
|
Y -> S (in sporadic cancers; somatic mutation)
|
VAR_045194
|
Natural variant site
|
236 - 236
|
1
|
Y -> F (in a sporadic cancer; somatic mutation)
|
VAR_045191
|
Natural variant site
|
236 - 236
|
1
|
Y -> H (in sporadic cancers; somatic mutation)
|
VAR_045192
|
Natural variant site
|
236 - 236
|
1
|
Y -> C (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_045189
|
Natural variant site
|
236 - 236
|
1
|
Y -> N (in sporadic cancers; somatic mutation)
|
VAR_045193
|
Natural variant site
|
237 - 237
|
1
|
M -> T (in sporadic cancers; somatic mutation)
|
VAR_045198
|
Natural variant site
|
237 - 237
|
1
|
M -> K (in sporadic cancers; somatic mutation)
|
VAR_045195
|
Natural variant site
|
237 - 237
|
1
|
M -> V (in sporadic cancers; somatic mutation)
|
VAR_045199
|
Natural variant site
|
237 - 237
|
1
|
M -> I (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_005965
|
Natural variant site
|
237 - 237
|
1
|
M -> R (in sporadic cancers; somatic mutation)
|
VAR_045197
|
Natural variant site
|
237 - 237
|
1
|
M -> L (in sporadic cancers; somatic mutation)
|
VAR_045196
|
Natural variant site
|
238 - 238
|
1
|
C -> S (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_045202
|
Natural variant site
|
238 - 238
|
1
|
C -> G (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_045200
|
Natural variant site
|
238 - 238
|
1
|
C -> H (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045850
|
Natural variant site
|
238 - 238
|
1
|
C -> W (in sporadic cancers; somatic mutation)
|
VAR_045203
|
Natural variant site
|
238 - 238
|
1
|
C -> R (in sporadic cancers; somatic mutation)
|
VAR_045201
|
Natural variant site
|
238 - 238
|
1
|
C -> F (in sporadic cancers; somatic mutation)
|
VAR_005966
|
Natural variant site
|
238 - 238
|
1
|
C -> Y (in a familial cancer not matching LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_005967
|
Natural variant site
|
239 - 239
|
1
|
N -> I (in a sporadic cancer; somatic mutation)
|
VAR_045206
|
Natural variant site
|
239 - 239
|
1
|
N -> K (in sporadic cancers; somatic mutation)
|
VAR_045207
|
Natural variant site
|
239 - 239
|
1
|
N -> S (in sporadic cancers; somatic mutation)
|
VAR_045208
|
Natural variant site
|
239 - 239
|
1
|
N -> Y (in sporadic cancers; somatic mutation)
|
VAR_045210
|
Natural variant site
|
239 - 239
|
1
|
N -> T (in sporadic cancers; somatic mutation)
|
VAR_045209
|
Natural variant site
|
239 - 239
|
1
|
N -> D (in sporadic cancers; somatic mutation)
|
VAR_045204
|
Natural variant site
|
239 - 239
|
1
|
N -> H (in a sporadic cancer; somatic mutation)
|
VAR_045205
|
Natural variant site
|
240 - 240
|
1
|
S -> N (in sporadic cancers; somatic mutation)
|
VAR_045213
|
Natural variant site
|
240 - 240
|
1
|
S -> T (in sporadic cancers; somatic mutation)
|
VAR_045216
|
Natural variant site
|
240 - 240
|
1
|
S -> G (in sporadic cancers; somatic mutation)
|
VAR_045212
|
Natural variant site
|
240 - 240
|
1
|
S -> R (in sporadic cancers; somatic mutation)
|
VAR_045215
|
Natural variant site
|
240 - 240
|
1
|
S -> I (in sporadic cancers; somatic mutation)
|
VAR_005968
|
Natural variant site
|
240 - 240
|
1
|
S -> C (in sporadic cancers; somatic mutation)
|
VAR_045211
|
Natural variant site
|
240 - 240
|
1
|
S -> P (in a sporadic cancer; somatic mutation)
|
VAR_045214
|
Natural variant site
|
241 - 241
|
1
|
S -> T (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_047183
|
Natural variant site
|
241 - 241
|
1
|
S -> Y (in sporadic cancers; somatic mutation)
|
VAR_045219
|
Natural variant site
|
241 - 241
|
1
|
S -> P (in sporadic cancers; somatic mutation)
|
VAR_045218
|
Natural variant site
|
241 - 241
|
1
|
S -> F (in LFS; germline mutation and in sporadic cancers; somatic mutation; dbSNP:rs28934573)
|
VAR_005969
|
Natural variant site
|
241 - 241
|
1
|
S -> A (in sporadic cancers; somatic mutation)
|
VAR_033036
|
Natural variant site
|
241 - 241
|
1
|
S -> C (in sporadic cancers; somatic mutation)
|
VAR_045217
|
Natural variant site
|
242 - 242
|
1
|
C -> G (in sporadic cancers; somatic mutation)
|
VAR_045220
|
Natural variant site
|
242 - 242
|
1
|
C -> Y (in a familial cancer not matching LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_045224
|
Natural variant site
|
242 - 242
|
1
|
C -> R (in sporadic cancers; somatic mutation)
|
VAR_045221
|
Natural variant site
|
242 - 242
|
1
|
C -> S (in sporadic cancers; somatic mutation)
|
VAR_045222
|
Natural variant site
|
242 - 242
|
1
|
C -> W (in sporadic cancers; somatic mutation)
|
VAR_045223
|
Natural variant site
|
242 - 242
|
1
|
C -> F (in sporadic cancers; somatic mutation)
|
VAR_005970
|
Natural variant site
|
243 - 244
|
2
|
MG -> IS (in a sporadic cancer; somatic mutation)
|
VAR_047185
|
Natural variant site
|
243 - 243
|
1
|
M -> I (in sporadic cancers; somatic mutation)
|
VAR_045225
|
Natural variant site
|
243 - 243
|
1
|
M -> K (in sporadic cancers; somatic mutation)
|
VAR_045226
|
Natural variant site
|
243 - 243
|
1
|
M -> V (in sporadic cancers; somatic mutation)
|
VAR_045230
|
Natural variant site
|
243 - 243
|
1
|
M -> T (in sporadic cancers; somatic mutation)
|
VAR_045229
|
Natural variant site
|
243 - 243
|
1
|
M -> L (in sporadic cancers; somatic mutation)
|
VAR_045227
|
Natural variant site
|
243 - 243
|
1
|
M -> R (in sporadic cancers; somatic mutation)
|
VAR_045228
|
Natural variant site
|
243 - 244
|
2
|
MG -> IC (in a sporadic cancer; somatic mutation)
|
VAR_047184
|
Natural variant site
|
244 - 244
|
1
|
G -> C (in sporadic cancers; somatic mutation)
|
VAR_045231
|
Natural variant site
|
244 - 244
|
1
|
G -> A (in sporadic cancers; somatic mutation)
|
VAR_047186
|
Natural variant site
|
244 - 244
|
1
|
G -> R (in sporadic cancers; somatic mutation)
|
VAR_045234
|
Natural variant site
|
244 - 244
|
1
|
G -> S (in sporadic cancers; somatic mutation)
|
VAR_045235
|
Natural variant site
|
244 - 244
|
1
|
G -> D (in LFS; germline mutation and in sporadic cancers; somatic mutation; dbSNP:rs28934572)
|
VAR_045232
|
Natural variant site
|
244 - 244
|
1
|
G -> E (in a sporadic cancer; somatic mutation)
|
VAR_045233
|
Natural variant site
|
244 - 244
|
1
|
G -> V (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_045236
|
Natural variant site
|
245 - 245
|
1
|
G -> S (in LFS; germline mutation and in sporadic cancers; somatic mutation; dbSNP:rs28934575)
|
VAR_005974
|
Natural variant site
|
245 - 245
|
1
|
G -> V (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_005975
|
Natural variant site
|
245 - 245
|
1
|
G -> C (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_005972
|
Natural variant site
|
245 - 245
|
1
|
G -> L (in sporadic cancers; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045853
|
Natural variant site
|
245 - 245
|
1
|
G -> R (in sporadic cancers; somatic mutation)
|
VAR_045238
|
Natural variant site
|
245 - 245
|
1
|
G -> A (in sporadic cancers; somatic mutation)
|
VAR_005971
|
Natural variant site
|
245 - 245
|
1
|
G -> H (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045852
|
Natural variant site
|
245 - 245
|
1
|
G -> F (in sporadic cancers; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045851
|
Natural variant site
|
245 - 245
|
1
|
G -> D (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_005973
|
Natural variant site
|
245 - 245
|
1
|
G -> E (in a sporadic cancer; somatic mutation)
|
VAR_045237
|
Natural variant site
|
245 - 245
|
1
|
G -> N (in sporadic cancers; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045854
|
Natural variant site
|
246 - 246
|
1
|
M -> I (in sporadic cancers; somatic mutation)
|
VAR_045239
|
Natural variant site
|
246 - 246
|
1
|
M -> R (in sporadic cancers; somatic mutation)
|
VAR_005976
|
Natural variant site
|
246 - 246
|
1
|
M -> V (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_005978
|
Natural variant site
|
246 - 246
|
1
|
M -> T (in sporadic cancers; somatic mutation)
|
VAR_005977
|
Natural variant site
|
246 - 246
|
1
|
M -> L (in sporadic cancers; somatic mutation)
|
VAR_044020
|
Natural variant site
|
246 - 246
|
1
|
M -> K (in sporadic cancers; somatic mutation)
|
VAR_045240
|
Natural variant site
|
247 - 247
|
1
|
N -> S (in sporadic cancers; somatic mutation)
|
VAR_045243
|
Natural variant site
|
247 - 248
|
2
|
NR -> KW (in sporadic cancers; somatic mutation)
|
VAR_047188
|
Natural variant site
|
247 - 247
|
1
|
N -> F (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045855
|
Natural variant site
|
247 - 247
|
1
|
N -> T (in sporadic cancers; somatic mutation)
|
VAR_047189
|
Natural variant site
|
247 - 247
|
1
|
N -> Y (in sporadic cancers; somatic mutation)
|
VAR_045244
|
Natural variant site
|
247 - 247
|
1
|
N -> K (in sporadic cancers; somatic mutation)
|
VAR_045242
|
Natural variant site
|
247 - 247
|
1
|
N -> D (in sporadic cancers; somatic mutation)
|
VAR_045241
|
Natural variant site
|
247 - 247
|
1
|
N -> I (in sporadic cancers; somatic mutation)
|
VAR_005980
|
Natural variant site
|
247 - 248
|
2
|
NR -> IP (in a sporadic cancer; somatic mutation)
|
VAR_047187
|
Natural variant site
|
248 - 248
|
1
|
R -> W (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_005984
|
Natural variant site
|
248 - 248
|
1
|
R -> P (in sporadic cancers; somatic mutation)
|
VAR_045246
|
Natural variant site
|
248 - 248
|
1
|
R -> Q (in LFS; germline mutation and in sporadic cancers; somatic mutation; dbSNP:rs11540652)
|
VAR_005983
|
Natural variant site
|
248 - 248
|
1
|
R -> L (in sporadic cancers; somatic mutation)
|
VAR_005982
|
Natural variant site
|
248 - 248
|
1
|
R -> G (in sporadic cancers; somatic mutation)
|
VAR_005981
|
Natural variant site
|
248 - 248
|
1
|
R -> C (in a sporadic cancer; somatic mutation)
|
VAR_045245
|
Natural variant site
|
249 - 249
|
1
|
R -> S (in sporadic cancers; somatic mutation; dbSNP:rs28934571)
|
VAR_005986
|
Natural variant site
|
249 - 250
|
2
|
RP -> SA (in a sporadic cancer; somatic mutation)
|
VAR_047190
|
Natural variant site
|
249 - 249
|
1
|
R -> G (in sporadic cancers; somatic mutation)
|
VAR_005985
|
Natural variant site
|
249 - 249
|
1
|
R -> M (in sporadic cancers; somatic mutation)
|
VAR_033037
|
Natural variant site
|
249 - 249
|
1
|
R -> N (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045856
|
Natural variant site
|
249 - 249
|
1
|
R -> K (in sporadic cancers; somatic mutation)
|
VAR_045248
|
Natural variant site
|
249 - 249
|
1
|
R -> T (in sporadic cancers; somatic mutation)
|
VAR_045249
|
Natural variant site
|
249 - 250
|
2
|
RP -> SS (in sporadic cancers; somatic mutation)
|
VAR_047191
|
Natural variant site
|
249 - 249
|
1
|
R -> W (in sporadic cancers; somatic mutation)
|
VAR_045250
|
Natural variant site
|
249 - 249
|
1
|
R -> I (in a sporadic cancer; somatic mutation)
|
VAR_045247
|
Natural variant site
|
250 - 250
|
1
|
P -> Q (in sporadic cancers; somatic mutation)
|
VAR_045253
|
Natural variant site
|
250 - 250
|
1
|
P -> N (in sporadic cancers; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045858
|
Natural variant site
|
250 - 250
|
1
|
P -> A (in sporadic cancers; somatic mutation)
|
VAR_045251
|
Natural variant site
|
250 - 250
|
1
|
P -> S (in sporadic cancers; somatic mutation)
|
VAR_045254
|
Natural variant site
|
250 - 250
|
1
|
P -> L (in sporadic cancers; somatic mutation)
|
VAR_047192
|
Natural variant site
|
250 - 250
|
1
|
P -> H (in sporadic cancers; somatic mutation)
|
VAR_045252
|
Natural variant site
|
250 - 250
|
1
|
P -> T (in sporadic cancers; somatic mutation)
|
VAR_045255
|
Natural variant site
|
250 - 250
|
1
|
P -> F (in sporadic cancers; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045857
|
Natural variant site
|
251 - 251
|
1
|
I -> M (in LFS; germline mutation)
|
VAR_045258
|
Natural variant site
|
251 - 251
|
1
|
I -> F (in sporadic cancers; somatic mutation)
|
VAR_045256
|
Natural variant site
|
251 - 251
|
1
|
I -> S (in sporadic cancers; somatic mutation)
|
VAR_033038
|
Natural variant site
|
251 - 251
|
1
|
I -> V (in sporadic cancers; somatic mutation)
|
VAR_045260
|
Natural variant site
|
251 - 251
|
1
|
I -> N (in sporadic cancers; somatic mutation)
|
VAR_005987
|
Natural variant site
|
251 - 251
|
1
|
I -> L (in sporadic cancers; somatic mutation)
|
VAR_045257
|
Natural variant site
|
251 - 251
|
1
|
I -> T (in sporadic cancers; somatic mutation)
|
VAR_045259
|
Natural variant site
|
252 - 252
|
1
|
L -> H (in a sporadic cancer; somatic mutation)
|
VAR_045262
|
Natural variant site
|
252 - 252
|
1
|
L -> V (in a sporadic cancer; somatic mutation)
|
VAR_045264
|
Natural variant site
|
252 - 252
|
1
|
L -> I (in sporadic cancers; somatic mutation)
|
VAR_045263
|
Natural variant site
|
252 - 252
|
1
|
L -> F (in sporadic cancers; somatic mutation)
|
VAR_045261
|
Natural variant site
|
252 - 252
|
1
|
L -> P (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_005988
|
Natural variant site
|
253 - 253
|
1
|
T -> N (in sporadic cancers; somatic mutation)
|
VAR_045267
|
Natural variant site
|
253 - 253
|
1
|
T -> I (in sporadic cancers; somatic mutation)
|
VAR_045266
|
Natural variant site
|
253 - 253
|
1
|
T -> S (in sporadic cancers; somatic mutation)
|
VAR_045268
|
Natural variant site
|
253 - 253
|
1
|
T -> P (in sporadic cancers; somatic mutation)
|
VAR_047193
|
Natural variant site
|
253 - 253
|
1
|
T -> A (in sporadic cancers; somatic mutation)
|
VAR_045265
|
Natural variant site
|
254 - 254
|
1
|
I -> S (in sporadic cancers; somatic mutation)
|
VAR_045272
|
Natural variant site
|
254 - 254
|
1
|
I -> L (in a sporadic cancer; somatic mutation)
|
VAR_045270
|
Natural variant site
|
254 - 254
|
1
|
I -> N (in sporadic cancers; somatic mutation)
|
VAR_017908
|
Natural variant site
|
254 - 254
|
1
|
I -> M (in a sporadic cancer; somatic mutation)
|
VAR_045271
|
Natural variant site
|
254 - 254
|
1
|
I -> T (in sporadic cancers; somatic mutation)
|
VAR_017909
|
Natural variant site
|
254 - 254
|
1
|
I -> D (in sporadic cancers; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045859
|
Natural variant site
|
254 - 254
|
1
|
I -> V (in sporadic cancers; somatic mutation)
|
VAR_045273
|
Natural variant site
|
254 - 254
|
1
|
I -> F (in a sporadic cancer; somatic mutation)
|
VAR_045269
|
Natural variant site
|
255 - 255
|
1
|
I -> F (in sporadic cancers; somatic mutation)
|
VAR_045274
|
Natural variant site
|
255 - 255
|
1
|
I -> S (in sporadic cancers; somatic mutation)
|
VAR_045277
|
Natural variant site
|
255 - 255
|
1
|
I -> M (in sporadic cancers; somatic mutation)
|
VAR_045275
|
Natural variant site
|
255 - 255
|
1
|
I -> V (in sporadic cancers; somatic mutation)
|
VAR_045279
|
Natural variant site
|
255 - 255
|
1
|
I -> T (in sporadic cancers; somatic mutation)
|
VAR_045278
|
Natural variant site
|
255 - 255
|
1
|
I -> N (in sporadic cancers; somatic mutation)
|
VAR_045276
|
Natural variant site
|
256 - 256
|
1
|
T -> S (in sporadic cancers; somatic mutation)
|
VAR_045283
|
Natural variant site
|
256 - 256
|
1
|
T -> P (in sporadic cancers; somatic mutation)
|
VAR_045282
|
Natural variant site
|
256 - 256
|
1
|
T -> I (in a brain tumor with no family history; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_045280
|
Natural variant site
|
256 - 256
|
1
|
T -> K (in sporadic cancers; somatic mutation)
|
VAR_045281
|
Natural variant site
|
257 - 257
|
1
|
L -> V (in sporadic cancers; somatic mutation)
|
VAR_045286
|
Natural variant site
|
257 - 257
|
1
|
L -> Q (in LFS; germline mutation and in sporadic cancers; somatic mutation; dbSNP:rs28934577)
|
VAR_045284
|
Natural variant site
|
257 - 257
|
1
|
L -> P (in sporadic cancers; somatic mutation)
|
VAR_005989
|
Natural variant site
|
257 - 257
|
1
|
L -> R (in sporadic cancers; somatic mutation)
|
VAR_045285
|
Natural variant site
|
258 - 258
|
1
|
E -> L (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045860
|
Natural variant site
|
258 - 258
|
1
|
E -> G (in sporadic cancers; somatic mutation)
|
VAR_045288
|
Natural variant site
|
258 - 258
|
1
|
E -> A (in sporadic cancers; somatic mutation)
|
VAR_045287
|
Natural variant site
|
258 - 258
|
1
|
E -> Q (in sporadic cancers; somatic mutation)
|
VAR_045289
|
Natural variant site
|
258 - 258
|
1
|
E -> K (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_005991
|
Natural variant site
|
258 - 258
|
1
|
E -> V (in sporadic cancers; somatic mutation)
|
VAR_045290
|
Natural variant site
|
258 - 258
|
1
|
E -> D (in sporadic cancers; somatic mutation)
|
VAR_005990
|
Natural variant site
|
259 - 259
|
1
|
D -> N (in sporadic cancers; somatic mutation)
|
VAR_045294
|
Natural variant site
|
259 - 259
|
1
|
D -> S (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045862
|
Natural variant site
|
259 - 259
|
1
|
D -> E (in sporadic cancers; somatic mutation)
|
VAR_045291
|
Natural variant site
|
259 - 259
|
1
|
D -> Y (in sporadic cancers; somatic mutation)
|
VAR_033039
|
Natural variant site
|
259 - 259
|
1
|
D -> V (in sporadic cancers; somatic mutation)
|
VAR_045295
|
Natural variant site
|
259 - 259
|
1
|
D -> P (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045861
|
Natural variant site
|
259 - 259
|
1
|
D -> G (in sporadic cancers; somatic mutation)
|
VAR_045292
|
Natural variant site
|
259 - 259
|
1
|
D -> A (in a sporadic cancer; somatic mutation)
|
VAR_047194
|
Natural variant site
|
259 - 259
|
1
|
D -> H (in sporadic cancers; somatic mutation)
|
VAR_045293
|
Natural variant site
|
260 - 260
|
1
|
S -> Y (in sporadic cancers; somatic mutation)
|
VAR_045301
|
Natural variant site
|
260 - 260
|
1
|
S -> T (in a sporadic cancer; somatic mutation)
|
VAR_045300
|
Natural variant site
|
260 - 260
|
1
|
S -> C (in sporadic cancers; somatic mutation)
|
VAR_045297
|
Natural variant site
|
260 - 260
|
1
|
S -> A (in sporadic cancers; somatic mutation)
|
VAR_045296
|
Natural variant site
|
260 - 260
|
1
|
S -> F (in sporadic cancers; somatic mutation)
|
VAR_045298
|
Natural variant site
|
260 - 260
|
1
|
S -> P (in sporadic cancers; somatic mutation)
|
VAR_045299
|
Natural variant site
|
261 - 261
|
1
|
S -> R (in sporadic cancers; somatic mutation)
|
VAR_045306
|
Natural variant site
|
261 - 261
|
1
|
S -> N (in a sporadic cancer; somatic mutation)
|
VAR_045305
|
Natural variant site
|
261 - 261
|
1
|
S -> I (in sporadic cancers; somatic mutation)
|
VAR_045304
|
Natural variant site
|
261 - 261
|
1
|
S -> G (in sporadic cancers; somatic mutation)
|
VAR_045303
|
Natural variant site
|
261 - 261
|
1
|
S -> C (in a sporadic cancer; somatic mutation)
|
VAR_045302
|
Natural variant site
|
262 - 263
|
2
|
GN -> PD (in a sporadic cancer; somatic mutation)
|
VAR_047195
|
Natural variant site
|
262 - 262
|
1
|
G -> D (in sporadic cancers; somatic mutation)
|
VAR_047196
|
Natural variant site
|
262 - 262
|
1
|
G -> V (in sporadic cancers; somatic mutation)
|
VAR_045309
|
Natural variant site
|
262 - 262
|
1
|
G -> S (in sporadic cancers; somatic mutation)
|
VAR_045308
|
Natural variant site
|
262 - 262
|
1
|
G -> H (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045863
|
Natural variant site
|
262 - 262
|
1
|
G -> C (in a sporadic cancer; somatic mutation)
|
VAR_045307
|
Natural variant site
|
263 - 263
|
1
|
N -> K (in a sporadic cancer; somatic mutation)
|
VAR_045313
|
Natural variant site
|
263 - 263
|
1
|
N -> I (in sporadic cancers; somatic mutation)
|
VAR_045312
|
Natural variant site
|
263 - 263
|
1
|
N -> H (in sporadic cancers; somatic mutation)
|
VAR_045311
|
Natural variant site
|
263 - 263
|
1
|
N -> S (in a sporadic cancer; somatic mutation)
|
VAR_045314
|
Natural variant site
|
263 - 263
|
1
|
N -> D (in sporadic cancers; somatic mutation)
|
VAR_045310
|
Natural variant site
|
264 - 264
|
1
|
L -> P (in a sporadic cancer; somatic mutation)
|
VAR_045316
|
Natural variant site
|
264 - 264
|
1
|
L -> R (in sporadic cancers; somatic mutation)
|
VAR_045318
|
Natural variant site
|
264 - 264
|
1
|
L -> Q (in a sporadic cancer; somatic mutation)
|
VAR_045317
|
Natural variant site
|
264 - 264
|
1
|
L -> I (in sporadic cancers; somatic mutation)
|
VAR_045315
|
Natural variant site
|
264 - 264
|
1
|
L -> V (in a sporadic cancer; somatic mutation)
|
VAR_045319
|
Natural variant site
|
265 - 265
|
1
|
L -> P (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_045321
|
Natural variant site
|
265 - 265
|
1
|
L -> R (in sporadic cancers; somatic mutation)
|
VAR_047197
|
Natural variant site
|
265 - 265
|
1
|
L -> M (in sporadic cancers; somatic mutation)
|
VAR_045320
|
Natural variant site
|
265 - 265
|
1
|
L -> Q (in sporadic cancers; somatic mutation)
|
VAR_045322
|
Natural variant site
|
266 - 266
|
1
|
G -> R (in sporadic cancers; somatic mutation)
|
VAR_045325
|
Natural variant site
|
266 - 266
|
1
|
G -> E (in sporadic cancers; somatic mutation)
|
VAR_045324
|
Natural variant site
|
266 - 266
|
1
|
G -> V (in sporadic cancers; somatic mutation)
|
VAR_045326
|
Natural variant site
|
266 - 266
|
1
|
G -> A (in sporadic cancers; somatic mutation)
|
VAR_045323
|
Natural variant site
|
267 - 267
|
1
|
R -> Q (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_045330
|
Natural variant site
|
267 - 267
|
1
|
R -> H (in a sporadic cancer; somatic mutation)
|
VAR_045328
|
Natural variant site
|
267 - 267
|
1
|
R -> W (in sporadic cancers; somatic mutation; dbSNP:rs55832599)
|
VAR_036507
|
Natural variant site
|
267 - 267
|
1
|
R -> P (in sporadic cancers; somatic mutation)
|
VAR_045329
|
Natural variant site
|
267 - 267
|
1
|
R -> G (in sporadic cancers; somatic mutation)
|
VAR_045327
|
Natural variant site
|
268 - 268
|
1
|
N -> I (in sporadic cancers; somatic mutation)
|
VAR_045332
|
Natural variant site
|
268 - 268
|
1
|
N -> S (in sporadic cancers; somatic mutation)
|
VAR_045334
|
Natural variant site
|
268 - 268
|
1
|
N -> F (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045864
|
Natural variant site
|
268 - 268
|
1
|
N -> Y (in a sporadic cancer; somatic mutation)
|
VAR_045335
|
Natural variant site
|
268 - 268
|
1
|
N -> K (in a sporadic cancer; somatic mutation)
|
VAR_045333
|
Natural variant site
|
268 - 268
|
1
|
N -> H (in sporadic cancers; somatic mutation)
|
VAR_045331
|
Natural variant site
|
269 - 269
|
1
|
S -> C (in sporadic cancers; somatic mutation)
|
VAR_045336
|
Natural variant site
|
269 - 269
|
1
|
S -> R (in sporadic cancers; somatic mutation)
|
VAR_045339
|
Natural variant site
|
269 - 269
|
1
|
S -> I (in a sporadic cancer; somatic mutation)
|
VAR_047198
|
Natural variant site
|
269 - 269
|
1
|
S -> T (in a sporadic cancer; somatic mutation)
|
VAR_045340
|
Natural variant site
|
269 - 269
|
1
|
S -> N (in sporadic cancers; somatic mutation)
|
VAR_045338
|
Natural variant site
|
269 - 269
|
1
|
S -> G (in sporadic cancers; somatic mutation)
|
VAR_045337
|
Natural variant site
|
270 - 270
|
1
|
F -> I (in sporadic cancers; somatic mutation)
|
VAR_045342
|
Natural variant site
|
270 - 270
|
1
|
F -> L (in sporadic cancers; somatic mutation)
|
VAR_045343
|
Natural variant site
|
270 - 270
|
1
|
F -> C (in sporadic cancers; somatic mutation)
|
VAR_045341
|
Natural variant site
|
270 - 270
|
1
|
F -> S (in sporadic cancers; somatic mutation)
|
VAR_045344
|
Natural variant site
|
270 - 270
|
1
|
F -> Y (in sporadic cancers; somatic mutation)
|
VAR_045346
|
Natural variant site
|
270 - 270
|
1
|
F -> V (in sporadic cancers; somatic mutation)
|
VAR_045345
|
Natural variant site
|
271 - 271
|
1
|
E -> R (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045866
|
Natural variant site
|
271 - 271
|
1
|
E -> P (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045865
|
Natural variant site
|
271 - 271
|
1
|
E -> V (in an osteosarcoma with no family history; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_047199
|
Natural variant site
|
271 - 271
|
1
|
E -> Q (in sporadic cancers; somatic mutation)
|
VAR_045350
|
Natural variant site
|
271 - 271
|
1
|
E -> G (in sporadic cancers; somatic mutation)
|
VAR_045349
|
Natural variant site
|
271 - 271
|
1
|
E -> A (in sporadic cancers; somatic mutation)
|
VAR_045347
|
Natural variant site
|
271 - 271
|
1
|
E -> K (in sporadic cancers; somatic mutation)
|
VAR_036508
|
Natural variant site
|
271 - 271
|
1
|
E -> D (in sporadic cancers; somatic mutation)
|
VAR_045348
|
Natural variant site
|
272 - 272
|
1
|
V -> E (in sporadic cancers; somatic mutation)
|
VAR_045352
|
Natural variant site
|
272 - 272
|
1
|
V -> G (in sporadic cancers; somatic mutation)
|
VAR_045353
|
Natural variant site
|
272 - 272
|
1
|
V -> M (in sporadic cancers; somatic mutation)
|
VAR_045354
|
Natural variant site
|
272 - 272
|
1
|
V -> L (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_005992
|
Natural variant site
|
272 - 272
|
1
|
V -> A (in a familial cancer not matching LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_045351
|
Natural variant site
|
273 - 273
|
1
|
R -> G (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_005994
|
Natural variant site
|
273 - 273
|
1
|
R -> Y (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045868
|
Natural variant site
|
273 - 273
|
1
|
R -> Q (in sporadic cancers; somatic mutation)
|
VAR_045356
|
Natural variant site
|
273 - 273
|
1
|
R -> H (in LFS; germline mutation and in sporadic cancers; somatic mutation; dbSNP:rs28934576)
|
VAR_005995
|
Natural variant site
|
273 - 273
|
1
|
R -> C (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_005993
|
Natural variant site
|
273 - 273
|
1
|
R -> L (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_036509
|
Natural variant site
|
273 - 273
|
1
|
R -> S (in a familial cancer not matching LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_045357
|
Natural variant site
|
273 - 273
|
1
|
R -> N (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045867
|
Natural variant site
|
273 - 273
|
1
|
R -> P (in sporadic cancers; somatic mutation)
|
VAR_045355
|
Natural variant site
|
274 - 274
|
1
|
V -> L (in sporadic cancers; somatic mutation)
|
VAR_045361
|
Natural variant site
|
274 - 274
|
1
|
V -> D (in sporadic cancers; somatic mutation)
|
VAR_045359
|
Natural variant site
|
274 - 274
|
1
|
V -> F (in sporadic cancers; somatic mutation)
|
VAR_005997
|
Natural variant site
|
274 - 274
|
1
|
V -> G (in sporadic cancers; somatic mutation)
|
VAR_047200
|
Natural variant site
|
274 - 274
|
1
|
V -> A (in sporadic cancers; somatic mutation)
|
VAR_045358
|
Natural variant site
|
274 - 274
|
1
|
V -> I (in sporadic cancers; somatic mutation)
|
VAR_045360
|
Natural variant site
|
275 - 275
|
1
|
C -> F (in sporadic cancers; somatic mutation)
|
VAR_045362
|
Natural variant site
|
275 - 275
|
1
|
C -> R (in sporadic cancers; somatic mutation)
|
VAR_045364
|
Natural variant site
|
275 - 275
|
1
|
C -> W (in sporadic cancers; somatic mutation)
|
VAR_005999
|
Natural variant site
|
275 - 275
|
1
|
C -> G (in sporadic cancers; somatic mutation)
|
VAR_045363
|
Natural variant site
|
275 - 275
|
1
|
C -> S (in sporadic cancers; somatic mutation)
|
VAR_045365
|
Natural variant site
|
275 - 275
|
1
|
C -> Y (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_005998
|
Natural variant site
|
276 - 276
|
1
|
A -> S (in sporadic cancers; somatic mutation)
|
VAR_045369
|
Natural variant site
|
276 - 276
|
1
|
A -> D (in sporadic cancers; somatic mutation)
|
VAR_045366
|
Natural variant site
|
276 - 276
|
1
|
A -> P (in sporadic cancers; somatic mutation)
|
VAR_045368
|
Natural variant site
|
276 - 276
|
1
|
A -> T (in sporadic cancers; somatic mutation)
|
VAR_045370
|
Natural variant site
|
276 - 276
|
1
|
A -> V (in sporadic cancers; somatic mutation)
|
VAR_045371
|
Natural variant site
|
276 - 276
|
1
|
A -> G (in sporadic cancers; somatic mutation)
|
VAR_045367
|
Natural variant site
|
277 - 277
|
1
|
C -> Y (in an osteosarcoma with no family history; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_045375
|
Natural variant site
|
277 - 277
|
1
|
C -> S (in sporadic cancers; somatic mutation)
|
VAR_045374
|
Natural variant site
|
277 - 277
|
1
|
C -> F (in sporadic cancers; somatic mutation)
|
VAR_045372
|
Natural variant site
|
277 - 277
|
1
|
C -> W (in sporadic cancers; somatic mutation)
|
VAR_047201
|
Natural variant site
|
277 - 277
|
1
|
C -> G (in sporadic cancers; somatic mutation)
|
VAR_006000
|
Natural variant site
|
277 - 277
|
1
|
C -> R (in sporadic cancers; somatic mutation)
|
VAR_045373
|
Natural variant site
|
278 - 278
|
1
|
P -> H (in sporadic cancers; somatic mutation)
|
VAR_006002
|
Natural variant site
|
278 - 278
|
1
|
P -> R (in sporadic cancers; somatic mutation)
|
VAR_045376
|
Natural variant site
|
278 - 278
|
1
|
P -> T (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_006005
|
Natural variant site
|
278 - 278
|
1
|
P -> F (in sporadic cancers; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045869
|
Natural variant site
|
278 - 278
|
1
|
P -> A (in sporadic cancers; somatic mutation; dbSNP:rs17849781)
|
VAR_006001
|
Natural variant site
|
278 - 278
|
1
|
P -> L (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_006003
|
Natural variant site
|
278 - 278
|
1
|
P -> S (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_006004
|
Natural variant site
|
279 - 279
|
1
|
G -> E (in sporadic cancers; somatic mutation)
|
VAR_006006
|
Natural variant site
|
279 - 279
|
1
|
G -> R (in sporadic cancers; somatic mutation)
|
VAR_045377
|
Natural variant site
|
279 - 279
|
1
|
G -> W (in sporadic cancers; somatic mutation)
|
VAR_045379
|
Natural variant site
|
279 - 279
|
1
|
G -> V (in sporadic cancers; somatic mutation)
|
VAR_045378
|
Natural variant site
|
280 - 280
|
1
|
R -> K (in a familial cancer not matching LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_006007
|
Natural variant site
|
280 - 280
|
1
|
R -> I (in sporadic cancers; somatic mutation)
|
VAR_006008
|
Natural variant site
|
280 - 280
|
1
|
R -> T (in sporadic cancers; somatic mutation)
|
VAR_006009
|
Natural variant site
|
280 - 280
|
1
|
R -> P (in a sporadic cancer; somatic mutation)
|
VAR_045381
|
Natural variant site
|
280 - 280
|
1
|
R -> S (in sporadic cancers; somatic mutation)
|
VAR_045382
|
Natural variant site
|
280 - 280
|
1
|
R -> G (in sporadic cancers; somatic mutation)
|
VAR_045380
|
Natural variant site
|
281 - 281
|
1
|
D -> N (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_047202
|
Natural variant site
|
281 - 281
|
1
|
D -> A (in sporadic cancers; somatic mutation)
|
VAR_006010
|
Natural variant site
|
281 - 281
|
1
|
D -> Y (in sporadic cancers; somatic mutation)
|
VAR_045383
|
Natural variant site
|
281 - 282
|
2
|
DR -> EW (in sporadic cancers; somatic mutation)
|
VAR_047203
|
Natural variant site
|
281 - 281
|
1
|
D -> H (in sporadic cancers; somatic mutation)
|
VAR_006013
|
Natural variant site
|
281 - 281
|
1
|
D -> G (in a brain tumor with no family history; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_006012
|
Natural variant site
|
281 - 281
|
1
|
D -> V (in a familial cancer not matching LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_006014
|
Natural variant site
|
281 - 281
|
1
|
D -> E (in sporadic cancers; somatic mutation)
|
VAR_006011
|
Natural variant site
|
281 - 281
|
1
|
D -> R (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045870
|
Natural variant site
|
282 - 282
|
1
|
R -> H (in a sporadic cancer; somatic mutation)
|
VAR_045385
|
Natural variant site
|
282 - 282
|
1
|
R -> G (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_045384
|
Natural variant site
|
282 - 282
|
1
|
R -> L (in sporadic cancers; somatic mutation)
|
VAR_006015
|
Natural variant site
|
282 - 282
|
1
|
R -> P (in sporadic cancers; somatic mutation)
|
VAR_045386
|
Natural variant site
|
282 - 282
|
1
|
R -> Q (in a familial cancer not matching LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_045387
|
Natural variant site
|
282 - 282
|
1
|
R -> W (in LFS; germline mutation and in sporadic cancers; somatic mutation; dbSNP:rs28934574)
|
VAR_006016
|
Natural variant site
|
283 - 283
|
1
|
R -> G (in sporadic cancers; somatic mutation)
|
VAR_006018
|
Natural variant site
|
283 - 283
|
1
|
R -> H (in a brain tumor with no family history; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_006019
|
Natural variant site
|
283 - 283
|
1
|
R -> S (in a sporadic cancer; somatic mutation)
|
VAR_045389
|
Natural variant site
|
283 - 283
|
1
|
R -> C (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_006017
|
Natural variant site
|
283 - 283
|
1
|
R -> P (in sporadic cancers; somatic mutation)
|
VAR_006020
|
Natural variant site
|
283 - 283
|
1
|
R -> L (in sporadic cancers; somatic mutation)
|
VAR_045388
|
Natural variant site
|
284 - 284
|
1
|
T -> I (in sporadic cancers; somatic mutation)
|
VAR_045390
|
Natural variant site
|
284 - 284
|
1
|
T -> K (in sporadic cancers; somatic mutation)
|
VAR_045391
|
Natural variant site
|
284 - 284
|
1
|
T -> P (in sporadic cancers; somatic mutation)
|
VAR_006022
|
Natural variant site
|
284 - 284
|
1
|
T -> A (in sporadic cancers; somatic mutation)
|
VAR_006021
|
Natural variant site
|
285 - 285
|
1
|
E -> K (in sporadic cancers; somatic mutation)
|
VAR_006023
|
Natural variant site
|
285 - 285
|
1
|
E -> D (in sporadic cancers; somatic mutation)
|
VAR_045393
|
Natural variant site
|
285 - 285
|
1
|
E -> A (in a sporadic cancer; somatic mutation)
|
VAR_045392
|
Natural variant site
|
285 - 285
|
1
|
E -> V (in sporadic cancers; somatic mutation)
|
VAR_006025
|
Natural variant site
|
285 - 285
|
1
|
E -> Q (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_006024
|
Natural variant site
|
285 - 285
|
1
|
E -> G (in sporadic cancers; somatic mutation)
|
VAR_045394
|
Natural variant site
|
286 - 286
|
1
|
E -> A (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_006026
|
Natural variant site
|
286 - 286
|
1
|
E -> G (in sporadic cancers; somatic mutation)
|
VAR_006028
|
Natural variant site
|
286 - 286
|
1
|
E -> V (in sporadic cancers; somatic mutation)
|
VAR_045395
|
Natural variant site
|
286 - 286
|
1
|
E -> D (in sporadic cancers; somatic mutation)
|
VAR_006027
|
Natural variant site
|
286 - 286
|
1
|
E -> L (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045871
|
Natural variant site
|
286 - 286
|
1
|
E -> K (in sporadic cancers; somatic mutation)
|
VAR_006029
|
Natural variant site
|
286 - 286
|
1
|
E -> Q (in sporadic cancers; somatic mutation)
|
VAR_006030
|
Natural variant site
|
287 - 287
|
1
|
E -> K (in sporadic cancers; somatic mutation)
|
VAR_045398
|
Natural variant site
|
287 - 287
|
1
|
E -> V (in sporadic cancers; somatic mutation)
|
VAR_045399
|
Natural variant site
|
287 - 287
|
1
|
E -> D (in sporadic cancers; somatic mutation)
|
VAR_045396
|
Natural variant site
|
287 - 287
|
1
|
E -> G (in sporadic cancers; somatic mutation)
|
VAR_045397
|
Natural variant site
|
287 - 287
|
1
|
E -> A (in a sporadic cancer; somatic mutation)
|
VAR_047204
|
Natural variant site
|
288 - 288
|
1
|
N -> D (in a sporadic cancer; somatic mutation)
|
VAR_045400
|
Natural variant site
|
288 - 288
|
1
|
N -> S (in sporadic cancers; somatic mutation)
|
VAR_045402
|
Natural variant site
|
288 - 288
|
1
|
N -> Y (in sporadic cancers; somatic mutation)
|
VAR_045404
|
Natural variant site
|
288 - 288
|
1
|
N -> K (in sporadic cancers; somatic mutation)
|
VAR_045401
|
Natural variant site
|
288 - 288
|
1
|
N -> T (in sporadic cancers; somatic mutation)
|
VAR_045403
|
Natural variant site
|
289 - 289
|
1
|
L -> F (in sporadic cancers; somatic mutation)
|
VAR_045405
|
Natural variant site
|
289 - 289
|
1
|
L -> R (in a sporadic cancer; somatic mutation)
|
VAR_045408
|
Natural variant site
|
289 - 289
|
1
|
L -> V (in sporadic cancers; somatic mutation)
|
VAR_045409
|
Natural variant site
|
289 - 289
|
1
|
L -> P (in sporadic cancers; somatic mutation)
|
VAR_045407
|
Natural variant site
|
289 - 289
|
1
|
L -> H (in sporadic cancers; somatic mutation)
|
VAR_045406
|
Natural variant site
|
290 - 290
|
1
|
R -> L (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_045412
|
Natural variant site
|
290 - 290
|
1
|
R -> H (in LFS; germline mutation and in sporadic cancers; somatic mutation; dbSNP:rs55819519)
|
VAR_045411
|
Natural variant site
|
290 - 290
|
1
|
R -> C (in sporadic cancers; somatic mutation)
|
VAR_045410
|
Natural variant site
|
291 - 291
|
1
|
K -> Q (in sporadic cancers; somatic mutation)
|
VAR_047205
|
Natural variant site
|
291 - 291
|
1
|
K -> T (in sporadic cancers; somatic mutation)
|
VAR_045417
|
Natural variant site
|
291 - 291
|
1
|
K -> E (in sporadic cancers; somatic mutation)
|
VAR_045413
|
Natural variant site
|
291 - 291
|
1
|
K -> R (in sporadic cancers; somatic mutation)
|
VAR_045416
|
Natural variant site
|
291 - 291
|
1
|
K -> N (in sporadic cancers; somatic mutation)
|
VAR_045415
|
Natural variant site
|
291 - 291
|
1
|
K -> M (in sporadic cancers; somatic mutation)
|
VAR_045414
|
Natural variant site
|
292 - 292
|
1
|
K -> T (in sporadic cancers; somatic mutation)
|
VAR_045422
|
Natural variant site
|
292 - 292
|
1
|
K -> Q (in a sporadic cancer; somatic mutation)
|
VAR_045420
|
Natural variant site
|
292 - 292
|
1
|
K -> G (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045872
|
Natural variant site
|
292 - 292
|
1
|
K -> R (in sporadic cancers; somatic mutation)
|
VAR_045421
|
Natural variant site
|
292 - 292
|
1
|
K -> N (in sporadic cancers; somatic mutation)
|
VAR_045419
|
Natural variant site
|
292 - 292
|
1
|
K -> E (in sporadic cancers; somatic mutation)
|
VAR_045418
|
Natural variant site
|
292 - 292
|
1
|
K -> I (in LFS; germline mutation and in a sporadic cancer; somatic mutation)
|
VAR_015819
|
Natural variant site
|
293 - 293
|
1
|
G -> A (in a sporadic cancer; somatic mutation)
|
VAR_045423
|
Natural variant site
|
293 - 293
|
1
|
G -> R (in sporadic cancers; somatic mutation)
|
VAR_045424
|
Natural variant site
|
293 - 293
|
1
|
G -> V (in sporadic cancers; somatic mutation)
|
VAR_045425
|
Natural variant site
|
293 - 293
|
1
|
G -> W (in a brain tumor with no family history; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_045426
|
Natural variant site
|
294 - 294
|
1
|
E -> Q (in sporadic cancers; somatic mutation)
|
VAR_045430
|
Natural variant site
|
294 - 294
|
1
|
E -> G (in sporadic cancers; somatic mutation)
|
VAR_045429
|
Natural variant site
|
294 - 294
|
1
|
E -> K (in sporadic cancers; somatic mutation)
|
VAR_047206
|
Natural variant site
|
294 - 294
|
1
|
E -> A (in a sporadic cancer; somatic mutation)
|
VAR_045427
|
Natural variant site
|
294 - 294
|
1
|
E -> V (in sporadic cancers; somatic mutation)
|
VAR_045431
|
Natural variant site
|
294 - 294
|
1
|
E -> D (in sporadic cancers; somatic mutation)
|
VAR_045428
|
Natural variant site
|
295 - 295
|
1
|
P -> L (in sporadic cancers; somatic mutation)
|
VAR_045433
|
Natural variant site
|
295 - 295
|
1
|
P -> S (in sporadic cancers; somatic mutation)
|
VAR_045435
|
Natural variant site
|
295 - 295
|
1
|
P -> R (in a sporadic cancer; somatic mutation)
|
VAR_045434
|
Natural variant site
|
295 - 295
|
1
|
P -> H (in a sporadic cancer; somatic mutation)
|
VAR_045432
|
Natural variant site
|
296 - 296
|
1
|
H -> D (in sporadic cancers; somatic mutation)
|
VAR_045436
|
Natural variant site
|
296 - 296
|
1
|
H -> Q (in sporadic cancers; somatic mutation)
|
VAR_045438
|
Natural variant site
|
296 - 296
|
1
|
H -> L (in sporadic cancers; somatic mutation)
|
VAR_047207
|
Natural variant site
|
296 - 296
|
1
|
H -> C (in sporadic cancers; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045873
|
Natural variant site
|
296 - 296
|
1
|
H -> P (in a sporadic cancer; somatic mutation)
|
VAR_006031
|
Natural variant site
|
296 - 296
|
1
|
H -> R (in a sporadic cancer; somatic mutation)
|
VAR_045439
|
Natural variant site
|
296 - 296
|
1
|
H -> Y (in sporadic cancers; somatic mutation)
|
VAR_045440
|
Natural variant site
|
296 - 296
|
1
|
H -> N (in sporadic cancers; somatic mutation)
|
VAR_045437
|
Natural variant site
|
297 - 297
|
1
|
H -> N (in a sporadic cancer; somatic mutation)
|
VAR_045442
|
Natural variant site
|
297 - 297
|
1
|
H -> Y (in sporadic cancers; somatic mutation)
|
VAR_045445
|
Natural variant site
|
297 - 297
|
1
|
H -> R (in sporadic cancers; somatic mutation)
|
VAR_045444
|
Natural variant site
|
297 - 297
|
1
|
H -> P (in sporadic cancers; somatic mutation)
|
VAR_045443
|
Natural variant site
|
297 - 297
|
1
|
H -> D (in a sporadic cancer; somatic mutation)
|
VAR_045441
|
Natural variant site
|
298 - 298
|
1
|
E -> A (in a sporadic cancer; somatic mutation)
|
VAR_045446
|
Natural variant site
|
298 - 298
|
1
|
E -> K (in sporadic cancers; somatic mutation)
|
VAR_045448
|
Natural variant site
|
298 - 298
|
1
|
E -> Q (in sporadic cancers; somatic mutation)
|
VAR_045449
|
Natural variant site
|
298 - 298
|
1
|
E -> D (in sporadic cancers; somatic mutation)
|
VAR_045447
|
Natural variant site
|
298 - 298
|
1
|
E -> V (in sporadic cancers; somatic mutation)
|
VAR_045450
|
Natural variant site
|
299 - 299
|
1
|
L -> Q (in sporadic cancers; somatic mutation)
|
VAR_045452
|
Natural variant site
|
299 - 299
|
1
|
L -> R (in a sporadic cancer; somatic mutation)
|
VAR_045453
|
Natural variant site
|
299 - 299
|
1
|
L -> P (in sporadic cancers; somatic mutation)
|
VAR_045451
|
Natural variant site
|
299 - 299
|
1
|
L -> V (in a sporadic cancer; somatic mutation)
|
VAR_045454
|
Natural variant site
|
300 - 300
|
1
|
P -> R (in a sporadic cancer; somatic mutation)
|
VAR_006032
|
Natural variant site
|
300 - 300
|
1
|
P -> S (in sporadic cancers; somatic mutation)
|
VAR_045457
|
Natural variant site
|
300 - 300
|
1
|
P -> A (in sporadic cancers; somatic mutation)
|
VAR_045455
|
Natural variant site
|
300 - 300
|
1
|
P -> L (in sporadic cancers; somatic mutation)
|
VAR_045456
|
Natural variant site
|
301 - 301
|
1
|
P -> T (in a sporadic cancer; somatic mutation)
|
VAR_047208
|
Natural variant site
|
301 - 301
|
1
|
P -> A (in sporadic cancers; somatic mutation)
|
VAR_045458
|
Natural variant site
|
301 - 301
|
1
|
P -> L (in sporadic cancers; somatic mutation)
|
VAR_006033
|
Natural variant site
|
301 - 301
|
1
|
P -> S (in sporadic cancers; somatic mutation)
|
VAR_045460
|
Natural variant site
|
301 - 301
|
1
|
P -> Q (in sporadic cancers; somatic mutation)
|
VAR_045459
|
Natural variant site
|
302 - 302
|
1
|
G -> E (in sporadic cancers; somatic mutation)
|
VAR_006034
|
Natural variant site
|
302 - 302
|
1
|
G -> A (in a sporadic cancer; somatic mutation)
|
VAR_045461
|
Natural variant site
|
302 - 302
|
1
|
G -> V (in a sporadic cancer; somatic mutation)
|
VAR_006035
|
Natural variant site
|
302 - 302
|
1
|
G -> R (in a sporadic cancer; somatic mutation)
|
VAR_045462
|
Natural variant site
|
303 - 303
|
1
|
S -> N (in sporadic cancers; somatic mutation)
|
VAR_045465
|
Natural variant site
|
303 - 303
|
1
|
S -> I (in sporadic cancers; somatic mutation)
|
VAR_045464
|
Natural variant site
|
303 - 303
|
1
|
S -> T (in sporadic cancers; somatic mutation)
|
VAR_045466
|
Natural variant site
|
303 - 303
|
1
|
S -> C (in sporadic cancers; somatic mutation)
|
VAR_045463
|
Natural variant site
|
304 - 304
|
1
|
T -> N (in a sporadic cancer; somatic mutation)
|
VAR_045469
|
Natural variant site
|
304 - 304
|
1
|
T -> A (in sporadic cancers; somatic mutation)
|
VAR_045467
|
Natural variant site
|
304 - 304
|
1
|
T -> S (in a sporadic cancer; somatic mutation)
|
VAR_047209
|
Natural variant site
|
304 - 304
|
1
|
T -> I (in sporadic cancers; somatic mutation)
|
VAR_045468
|
Natural variant site
|
305 - 305
|
1
|
K -> T (in a sporadic cancer; somatic mutation)
|
VAR_045474
|
Natural variant site
|
305 - 305
|
1
|
K -> R (in sporadic cancers; somatic mutation)
|
VAR_045473
|
Natural variant site
|
305 - 305
|
1
|
K -> E (in a sporadic cancer; somatic mutation)
|
VAR_045470
|
Natural variant site
|
305 - 305
|
1
|
K -> M (in a familial cancer not matching LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_045471
|
Natural variant site
|
305 - 305
|
1
|
K -> N (in sporadic cancers; somatic mutation)
|
VAR_045472
|
Natural variant site
|
306 - 306
|
1
|
R -> Q (in sporadic cancers; somatic mutation)
|
VAR_006036
|
Natural variant site
|
306 - 306
|
1
|
R -> P (in LFS; germline mutation and in a sporadic cancer; somatic mutation)
|
VAR_045475
|
Natural variant site
|
307 - 307
|
1
|
A -> P (in a sporadic cancer; somatic mutation)
|
VAR_045476
|
Natural variant site
|
307 - 307
|
1
|
A -> S (in sporadic cancers; somatic mutation)
|
VAR_045477
|
Natural variant site
|
307 - 307
|
1
|
A -> T (in sporadic cancers; somatic mutation)
|
VAR_006037
|
Natural variant site
|
308 - 308
|
1
|
L -> V (in a sporadic cancer; somatic mutation)
|
VAR_045479
|
Natural variant site
|
308 - 308
|
1
|
L -> M (in sporadic cancers; somatic mutation)
|
VAR_045478
|
Natural variant site
|
309 - 309
|
1
|
P -> S (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_006038
|
Natural variant site
|
309 - 309
|
1
|
P -> R (in a sporadic cancer; somatic mutation)
|
VAR_045480
|
Natural variant site
|
310 - 310
|
1
|
N -> T (in sporadic cancers; somatic mutation)
|
VAR_045482
|
Natural variant site
|
310 - 310
|
1
|
N -> I (in a sporadic cancer; somatic mutation)
|
VAR_045481
|
Natural variant site
|
311 - 311
|
1
|
N -> H (in sporadic cancers; somatic mutation)
|
VAR_045483
|
Natural variant site
|
311 - 311
|
1
|
N -> T (in sporadic cancers; somatic mutation)
|
VAR_045486
|
Natural variant site
|
311 - 311
|
1
|
N -> S (in a sporadic cancer; somatic mutation; dbSNP:rs56184981)
|
VAR_045485
|
Natural variant site
|
311 - 311
|
1
|
N -> K (in a sporadic cancer; somatic mutation)
|
VAR_045484
|
Natural variant site
|
312 - 312
|
1
|
T -> S (in sporadic cancers; somatic mutation)
|
VAR_045488
|
Natural variant site
|
312 - 312
|
1
|
T -> I (in sporadic cancers; somatic mutation)
|
VAR_045487
|
Natural variant site
|
313 - 313
|
1
|
S -> R (in a sporadic cancer; somatic mutation)
|
VAR_045492
|
Natural variant site
|
313 - 313
|
1
|
S -> C (in a sporadic cancer; somatic mutation)
|
VAR_045489
|
Natural variant site
|
313 - 313
|
1
|
S -> N (in a sporadic cancer; somatic mutation)
|
VAR_045491
|
Natural variant site
|
313 - 313
|
1
|
S -> I (in a sporadic cancer; somatic mutation)
|
VAR_045490
|
Natural variant site
|
314 - 314
|
1
|
S -> F (in a sporadic cancer; somatic mutation)
|
VAR_045493
|
Natural variant site
|
315 - 315
|
1
|
S -> F (in a sporadic cancer; somatic mutation)
|
VAR_045495
|
Natural variant site
|
315 - 315
|
1
|
S -> C (in a sporadic cancer; somatic mutation)
|
VAR_045494
|
Natural variant site
|
315 - 315
|
1
|
S -> P (in a sporadic cancer; somatic mutation)
|
VAR_045496
|
Natural variant site
|
316 - 316
|
1
|
P -> L (in a sporadic cancer; somatic mutation)
|
VAR_045497
|
Natural variant site
|
316 - 316
|
1
|
P -> T (in a sporadic cancer; somatic mutation)
|
VAR_045498
|
Natural variant site
|
317 - 317
|
1
|
Q -> K (in sporadic cancers; somatic mutation)
|
VAR_045500
|
Natural variant site
|
317 - 317
|
1
|
Q -> L (in a sporadic cancer; somatic mutation)
|
VAR_047210
|
Natural variant site
|
317 - 317
|
1
|
Q -> P (in a sporadic cancer; somatic mutation)
|
VAR_045501
|
Natural variant site
|
317 - 317
|
1
|
Q -> R (in sporadic cancers; somatic mutation)
|
VAR_045502
|
Natural variant site
|
317 - 317
|
1
|
Q -> H (in a kidney cancer with no family history; germline mutation and in a sporadic cancer; somatic mutation)
|
VAR_045499
|
Natural variant site
|
318 - 318
|
1
|
P -> L (in sporadic cancers; somatic mutation)
|
VAR_045503
|
Natural variant site
|
319 - 319
|
1
|
K -> E (in sporadic cancers; somatic mutation)
|
VAR_045504
|
Natural variant site
|
319 - 319
|
1
|
K -> R (in a sporadic cancer; somatic mutation)
|
VAR_045506
|
Natural variant site
|
319 - 319
|
1
|
K -> N (in a sporadic cancer; somatic mutation)
|
VAR_045505
|
Natural variant site
|
320 - 320
|
1
|
K -> N (in sporadic cancers; somatic mutation)
|
VAR_045507
|
Natural variant site
|
321 - 321
|
1
|
K -> E (in kidney cancer; germline mutation)
|
VAR_045508
|
Natural variant site
|
321 - 321
|
1
|
K -> R (in a sporadic cancer; somatic mutation)
|
VAR_045509
|
Natural variant site
|
322 - 322
|
1
|
P -> L (in sporadic cancers; somatic mutation)
|
VAR_045510
|
Natural variant site
|
322 - 322
|
1
|
P -> R (in sporadic cancers; somatic mutation)
|
VAR_045511
|
Natural variant site
|
323 - 323
|
1
|
L -> M (in a sporadic cancer; somatic mutation)
|
VAR_045512
|
Natural variant site
|
323 - 323
|
1
|
L -> P (in a sporadic cancer; somatic mutation)
|
VAR_045513
|
Natural variant site
|
323 - 323
|
1
|
L -> R (in a sporadic cancer; somatic mutation)
|
VAR_045514
|
Natural variant site
|
323 - 323
|
1
|
L -> G (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045874
|
Natural variant site
|
323 - 323
|
1
|
L -> V (in a sporadic cancer; somatic mutation)
|
VAR_047211
|
Natural variant site
|
324 - 324
|
1
|
D -> Y (in a sporadic cancer; somatic mutation)
|
VAR_045516
|
Natural variant site
|
324 - 324
|
1
|
D -> E (in sporadic cancers; somatic mutation)
|
VAR_045515
|
Natural variant site
|
324 - 324
|
1
|
D -> S (in a sporadic cancer; somatic mutation; requires 2 nucleotide substitutions)
|
VAR_045875
|
Natural variant site
|
325 - 325
|
1
|
G -> A (in a sporadic cancer; somatic mutation)
|
VAR_045517
|
Natural variant site
|
325 - 325
|
1
|
G -> V (in LFS; germline mutation; dbSNP:rs28934271)
|
VAR_006039
|
Natural variant site
|
325 - 325
|
1
|
G -> E (in sporadic cancers; somatic mutation)
|
VAR_045518
|
Natural variant site
|
326 - 326
|
1
|
E -> G (in a sporadic cancer; somatic mutation)
|
VAR_045519
|
Natural variant site
|
327 - 327
|
1
|
Y -> H (in a sporadic cancer; somatic mutation)
|
VAR_045520
|
Natural variant site
|
327 - 327
|
1
|
Y -> S (in a sporadic cancer; somatic mutation)
|
VAR_045521
|
Natural variant site
|
328 - 328
|
1
|
F -> L (in a sporadic cancer; somatic mutation)
|
VAR_045522
|
Natural variant site
|
328 - 328
|
1
|
F -> S (in sporadic cancers; somatic mutation)
|
VAR_045523
|
Natural variant site
|
328 - 328
|
1
|
F -> V (in a sporadic cancer; somatic mutation)
|
VAR_045524
|
Natural variant site
|
329 - 329
|
1
|
T -> S (in a sporadic cancer; somatic mutation)
|
VAR_045526
|
Natural variant site
|
329 - 329
|
1
|
T -> I (in a sporadic cancer; somatic mutation)
|
VAR_045525
|
Natural variant site
|
330 - 330
|
1
|
L -> H (in sporadic cancers; somatic mutation)
|
VAR_045527
|
Natural variant site
|
330 - 330
|
1
|
L -> R (in sporadic cancers; somatic mutation)
|
VAR_045528
|
Natural variant site
|
330 - 330
|
1
|
L -> P (in a sporadic cancer; somatic mutation)
|
VAR_047212
|
Natural variant site
|
331 - 331
|
1
|
Q -> H (in sporadic cancers; somatic mutation)
|
VAR_045529
|
Natural variant site
|
331 - 331
|
1
|
Q -> R (in sporadic cancers; somatic mutation)
|
VAR_045531
|
Natural variant site
|
331 - 331
|
1
|
Q -> P (in sporadic cancers; somatic mutation)
|
VAR_045530
|
Natural variant site
|
332 - 332
|
1
|
I -> V (in a sporadic cancer; somatic mutation)
|
VAR_045532
|
Natural variant site
|
334 - 334
|
1
|
G -> W (in a sporadic cancer; somatic mutation)
|
VAR_045533
|
Natural variant site
|
334 - 334
|
1
|
G -> V (in sporadic cancers; somatic mutation)
|
VAR_006040
|
Natural variant site
|
335 - 335
|
1
|
R -> H (in a sporadic cancer; somatic mutation)
|
VAR_045535
|
Natural variant site
|
335 - 335
|
1
|
R -> L (in a sporadic cancer; somatic mutation)
|
VAR_045536
|
Natural variant site
|
335 - 335
|
1
|
R -> G (in a sporadic cancer; somatic mutation)
|
VAR_045534
|
Natural variant site
|
337 - 337
|
1
|
R -> H (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_035016
|
Natural variant site
|
337 - 337
|
1
|
R -> C (in LFS; germline mutation and in sporadic cancers; somatic mutation)
|
VAR_006041
|
Natural variant site
|
337 - 337
|
1
|
R -> P (in sporadic cancers; somatic mutation)
|
VAR_045538
|
Natural variant site
|
337 - 337
|
1
|
R -> L (in sporadic cancers; somatic mutation)
|
VAR_045537
|
Natural variant site
|
338 - 338
|
1
|
F -> I (in a sporadic cancer; somatic mutation)
|
VAR_045539
|
Natural variant site
|
338 - 338
|
1
|
F -> L (in a sporadic cancer; somatic mutation)
|
VAR_045540
|
Natural variant site
|
339 - 339
|
1
|
E -> Q (in a sporadic cancer; somatic mutation)
|
VAR_045541
|
Natural variant site
|
339 - 339
|
1
|
E -> K (in a sporadic cancer; somatic mutation; dbSNP:rs17882252)
|
VAR_022316
|
Natural variant site
|
341 - 341
|
1
|
F -> C (in sporadic cancers; somatic mutation)
|
VAR_045542
|
Natural variant site
|
342 - 342
|
1
|
R -> P (in sporadic cancers; somatic mutation)
|
VAR_045544
|
Natural variant site
|
342 - 342
|
1
|
R -> Q (in sporadic cancers; somatic mutation)
|
VAR_047213
|
Natural variant site
|
342 - 342
|
1
|
R -> L (in a sporadic cancer; somatic mutation)
|
VAR_045543
|
Natural variant site
|
343 - 343
|
1
|
E -> G (in sporadic cancers; somatic mutation)
|
VAR_045545
|
Natural variant site
|
344 - 344
|
1
|
L -> R (in a sporadic cancer; somatic mutation)
|
VAR_045547
|
Natural variant site
|
344 - 344
|
1
|
L -> P (in LFS; germline mutation and in a sporadic cancer; somatic mutation)
|
VAR_045546
|
Natural variant site
|
346 - 346
|
1
|
E -> A (in a sporadic cancer; somatic mutation)
|
VAR_045548
|
Natural variant site
|
347 - 347
|
1
|
A -> T (in sporadic cancers; somatic mutation)
|
VAR_045550
|
Natural variant site
|
347 - 347
|
1
|
A -> G (in a sporadic cancer; somatic mutation)
|
VAR_045549
|
Natural variant site
|
348 - 348
|
1
|
L -> F (in a sporadic cancer; somatic mutation)
|
VAR_045551
|
Natural variant site
|
348 - 348
|
1
|
L -> S (in a sporadic cancer; somatic mutation)
|
VAR_045552
|
Natural variant site
|
349 - 349
|
1
|
E -> D (in a sporadic cancer; somatic mutation)
|
VAR_045553
|
Natural variant site
|
352 - 352
|
1
|
D -> H (in a sporadic cancer; somatic mutation)
|
VAR_045554
|
Natural variant site
|
353 - 353
|
1
|
A -> T (in a sporadic cancer; somatic mutation)
|
VAR_045555
|
Natural variant site
|
354 - 354
|
1
|
Q -> R (in sporadic cancers; somatic mutation)
|
VAR_047214
|
Natural variant site
|
354 - 354
|
1
|
Q -> E (in a sporadic cancer; somatic mutation)
|
VAR_045556
|
Natural variant site
|
354 - 354
|
1
|
Q -> K (in a sporadic cancer; somatic mutation)
|
VAR_045557
|
Natural variant site
|
356 - 356
|
1
|
G -> A (in a sporadic cancer; somatic mutation)
|
VAR_045558
|
Natural variant site
|
356 - 356
|
1
|
G -> W (in a sporadic cancer; somatic mutation)
|
VAR_045559
|
Natural variant site
|
358 - 358
|
1
|
E -> D (in a sporadic cancer; somatic mutation)
|
VAR_045560
|
Natural variant site
|
358 - 358
|
1
|
E -> K (in a sporadic cancer; somatic mutation)
|
VAR_045561
|
Natural variant site
|
360 - 360
|
1
|
G -> A (in dbSNP:rs35993958)
|
VAR_045562
|
Natural variant site
|
360 - 360
|
1
|
G -> V (in a sporadic cancer; somatic mutation)
|
VAR_045563
|
Natural variant site
|
363 - 363
|
1
|
R -> K (in a sporadic cancer; somatic mutation)
|
VAR_045564
|
Natural variant site
|
364 - 364
|
1
|
A -> T (in a sporadic cancer; somatic mutation)
|
VAR_045566
|
Natural variant site
|
364 - 364
|
1
|
A -> P (in a sporadic cancer; somatic mutation)
|
VAR_045565
|
Natural variant site
|
364 - 364
|
1
|
A -> V (in a sporadic cancer; somatic mutation)
|
VAR_045567
|
Natural variant site
|
365 - 365
|
1
|
H -> Y (in a familial cancer not matching LFS; germline mutation and in a sporadic cancer; somatic mutation)
|
VAR_045568
|
Natural variant site
|
365 - 365
|
1
|
H -> R (in a sporadic cancer; somatic mutation)
|
VAR_047215
|
Natural variant site
|
366 - 366
|
1
|
S -> A (in a familial cancer not matching LFS; germline mutation and in sporadic cancers; somatic mutation; dbSNP:rs17881470)
|
VAR_022317
|
Natural variant site
|
370 - 370
|
1
|
K -> Q (in a sporadic cancer; somatic mutation)
|
VAR_045569
|
Natural variant site
|
376 - 376
|
1
|
S -> A (in a sporadic cancer; somatic mutation)
|
VAR_045570
|
Natural variant site
|
376 - 376
|
1
|
S -> T (in a sporadic cancer; somatic mutation)
|
VAR_045571
|
Natural variant site
|
379 - 379
|
1
|
R -> H (in sporadic cancers; somatic mutation)
|
VAR_045572
|
Natural variant site
|
385 - 385
|
1
|
F -> L (in a sporadic cancer; somatic mutation)
|
VAR_045573
|
Natural variant site
|
389 - 389
|
1
|
G -> W (in a sporadic cancer; somatic mutation)
|
VAR_045574
|
Natural variant site
|
392 - 392
|
1
|
S -> L (in a sporadic cancer; somatic mutation)
|
VAR_045575
|
Alternative sequence
|
332 - 341
|
10
|
IRGRERFEMF -> DGTSFQKENC
|
VSP_006535
|
Alternative sequence
|
342 - 393
|
52
|
Missing
|
VSP_006536
|
Amino acid modifications |
|
|
|
|
Crosslink
|
291 - 291
|
1
|
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)
|
P04637-CROSSLNK-291
|
Crosslink
|
292 - 292
|
1
|
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)
|
P04637-CROSSLNK-292
|
Crosslink
|
386 - 386
|
1
|
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)
|
P04637-CROSSLNK-386
|
Modified residue
|
9 - 9
|
1
|
Phosphoserine; by HIPK4
|
P04637-MOD_RES-9
|
Modified residue
|
15 - 15
|
1
|
Phosphoserine; by PRPK and ATM
|
P04637-MOD_RES-15
|
Modified residue
|
18 - 18
|
1
|
Phosphothreonine; by VRK1
|
P04637-MOD_RES-18
|
Modified residue
|
46 - 46
|
1
|
Phosphoserine; by HIPK2
|
P04637-MOD_RES-46
|
Modified residue
|
55 - 55
|
1
|
Phosphothreonine; by TAF1
|
P04637-MOD_RES-55
|
Modified residue
|
99 - 99
|
1
|
Phosphoserine
|
P04637-MOD_RES-99
|
Modified residue
|
292 - 292
|
1
|
N6-acetyllysine
|
P04637-MOD_RES-292
|
Modified residue
|
305 - 305
|
1
|
N6-acetyllysine
|
P04637-MOD_RES-305
|
Modified residue
|
313 - 313
|
1
|
Phosphoserine
|
P04637-MOD_RES-313
|
Modified residue
|
314 - 314
|
1
|
Phosphoserine
|
P04637-MOD_RES-314
|
Modified residue
|
315 - 315
|
1
|
Phosphoserine; by CDK1
|
P04637-MOD_RES-315
|
Modified residue
|
370 - 370
|
1
|
N6-methyllysine
|
P04637-MOD_RES-370
|
Modified residue
|
372 - 372
|
1
|
N6-methyllysine
|
P04637-MOD_RES-372
|
Modified residue
|
373 - 373
|
1
|
N6-acetyllysine
|
P04637-MOD_RES-373
|
Modified residue
|
381 - 381
|
1
|
N6-acetyllysine
|
P04637-MOD_RES-381
|
Modified residue
|
382 - 382
|
1
|
N6-acetyllysine
|
P04637-MOD_RES-382
|
Modified residue
|
392 - 392
|
1
|
Phosphoserine; by CK2
|
P04637-MOD_RES-392
|
Experimental info |
|
|
|
|
Mutagenesis
|
15 - 15
|
1
|
S->A: Loss of interaction with PPP2R5C, PPP2CA AND PPP2R1A
|
P04637-MUTAGEN-15
|
Mutagenesis
|
46 - 46
|
1
|
Missing: Alters interaction with WWOX
|
P04637-MUTAGEN-46
|
Mutagenesis
|
55 - 55
|
1
|
T->A: Blocks phosphorylation by TAF1
|
P04637-MUTAGEN-55
|
Mutagenesis
|
291 - 292
|
2
|
KK->RR: Abolishes polyubiquitination by MKRN1
|
P04637-MUTAGEN-291
|
Mutagenesis
|
359 - 359
|
1
|
P->D: Abolishes binding to USP7
|
P04637-MUTAGEN-359
|
Mutagenesis
|
361 - 361
|
1
|
G->E: Abolishes binding to USP7
|
P04637-MUTAGEN-361
|
Mutagenesis
|
362 - 362
|
1
|
S->A: Abolishes binding to USP7
|
P04637-MUTAGEN-362
|
Mutagenesis
|
370 - 370
|
1
|
K->R: Induces a decrease in methylation by SMYD2
|
P04637-MUTAGEN-370
|
Mutagenesis
|
372 - 372
|
1
|
K->R: Induces a decrease in protein stabilization
|
P04637-MUTAGEN-372
|
Mutagenesis
|
382 - 382
|
1
|
K->A: Abolishes acetylation by CREBBP
|
P04637-MUTAGEN-382
|
Mutagenesis
|
385 - 385
|
1
|
F->A: Reduced SUMO1 conjugation
|
P04637-MUTAGEN-385
|
Mutagenesis
|
386 - 386
|
1
|
K->A: Abolishes SUMO1 conjugation, in vitro and in vivo
|
P04637-MUTAGEN-386
|
Mutagenesis
|
387 - 387
|
1
|
T->A: No effect SUMO1 conjugation
|
P04637-MUTAGEN-387
|
Mutagenesis
|
388 - 388
|
1
|
E->A: Abolishes SUMO1 conjugation
|
P04637-MUTAGEN-388
|