| (TSC2) tuberous sclerosis 2 [Homo sapiens] |
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Gene
Transcript(s)
Exon(s)
Protein(s)
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Accession
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7773
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Official symbol
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TSC2
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Official name
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tuberous sclerosis 2
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Gene type
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gene with protein product
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Organism
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Homo sapiens
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Location
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Chromosome 16 (NC_000016.9) : 2097989...2138712 (+)
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Map
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16p13.3
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Length
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40724 nt
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NM_000548.3
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TSC2, mRNA isoform 1
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NM_001077183.1
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TSC2, mRNA isoform 4
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NM_001114382.1
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TSC2, mRNA isoform 5
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Accession
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Name
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Organism
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Length
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P49815
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Tuberin
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Homo sapiens
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1807 aa
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| Synonyms |
FLJ43106; tuberin; TSC4; LAM
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| Alternative name(s) |
tuberin
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| Summary |
Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq].
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Related Articles in PubMed
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Go to ensembl 
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| 1 |
TCCGGCGGCG |
TCCCGGGGCC |
AGGGGGGTGC |
GCCTTTCTCC |
GCGTCGGGGC |
GGCCCGGAGC |
GCGGTGGCGC |
GGCGCGGGGT |
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| 81 |
AAGTGGCGGT |
CCCCACGGGG |
CAAGTGGCGG |
TCCCCACGGG |
GCAGCGGCCT |
AGAGAGGCGG |
ACCCCGCAGT |
GTCCGGGTCC |
|
| 161 |
CGGGCCCTCA |
CCCGCGCCCA |
CTGCAACCCG |
ACTCCGGAGC |
TCCGAGCATC |
CCTTAGTTTT |
AAGTCATGGC |
GGGTGCGAAC |
|
| 241 |
GGGTCTCTGC |
TGCAGGCGGC |
TCCGTGACAG |
CTCCTGCTTC |
ACATGGGTAG |
AGGAGAGACG |
GCAAACGTCG |
GGGCTCCCAG |
|
| 321 |
GACTTCGCGG |
CGGCAGTCCT |
AACCCGTGCA |
CTGAGTCGGG |
CGGGGCGGGC |
GGCAGCGTCT |
GAGTAGAGAG |
CTCTCTAGAC |
|
| 401 |
CAGGCCTGGT |
GTCTCCCGGG |
CTTTCCTAGG |
TGCCTGTTTG |
CGAGCTGGTC |
AGCTGGGCTG |
TAGTTGAGTT |
CTCCCAGGGA |
|
| 481 |
GTGTGGGAGG |
AAAGGTTATG |
CCCACCAGAG |
ACCCAGGGTC |
CTGACGGCTG |
GAGGTCCGCA |
GTGGGGAAGG |
TGGGCAGAGG |
|
| 561 |
TGTTGCTCAG |
ATGTCCCCAT |
TCCTGTTTCG |
TTTGCACAGA |
GGGGTTTTCT |
GGTGCGTCCT |
GGTCCACCAT |
GGCCAAACCA |
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| 641 |
ACAAGCAAAG |
ATTCAGGCTT |
GAAGGAGAAG |
TTTAAGATTC |
TGTTGGGACT |
GGGAACACCG |
AGGCCAAATC |
CCAGGTCTGC |
|
| 721 |
AGAGGGTAAA |
CAGACGGAGT |
TTATCATCAC |
CGCGGAAATA |
CTGAGAGTGA |
GTGAGCTACC |
TGTGTCTTTG |
CTAGGCTAGA |
|
| 801 |
GGGAAATGCA |
GAGAAGGCTG |
GGTTTGGTCT |
TGCACCAGGT |
TCTGTGGGAG |
ACGGGTTGCT |
GGCAACTGTC |
TACACAGGAA |
|
| 881 |
TGCTGTCTCC |
AGTACTTGGA |
GGCCGACATG |
TCCTTCCTCA |
GGAGACTTCG |
AAAGTCAGGA |
TCTTGGTGAC |
CTGGTTCAGG |
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| 961 |
CACACTTGAG |
TTACTATTCA |
GATGTTGATG |
AAAGAAAGCC |
CATCTTATAG |
ATGAGGCCTG |
AGTATCATCA |
TCTTCACAGG |
|
| 1041 |
TAAGGATATG |
TCCAGGTGTT |
ACATGATAAG |
ATGTGAGTTC |
CTGGGAGAAG |
TAGGTTCTTT |
ATTTTATTTT |
TTTTTTGAGA |
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| 1121 |
CTGAGTCTTG |
CTCTGTTGCC |
TAGGCTGGAG |
TGCAGTGGCA |
CAATCTCTGC |
TCGCTGCTAC |
CTCTGCCTCC |
CAGTTTCAAG |
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| 1201 |
TGGTTCTCCT |
GCCTCAGCCT |
CCTGAGTAGC |
TGGGACTACA |
GACACGTGCC |
ACCACACCCA |
TTTAATTTTT |
GTATTTTTAG |
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| 1281 |
TAGAGATGGA |
GTTTCACTAT |
CTTGGCCAGG |
CTGGTCTTGA |
ACTGCTGACC |
TCAGGTGATC |
TGCCCGCTTT |
GGCCTCCCAA |
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| 1361 |
AGTGCTGGGA |
TTACAGGCAT |
GAGCCATCGC |
ACATGGGCTA |
GGTCGTTATC |
TTTTATGTGT |
GTTTGTGTCT |
TTGTCACACA |
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| 1441 |
TGCCTGGCAT |
TGTGTTTTGC |
CCATGAGTAA |
ATGCTGAATT |
TTTGCACTTG |
TAAAGTTTTC |
TACTTAGAAA |
CAACTAAAAC |
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| 1521 |
GTTCATCAAC |
TGATGAATAA |
AATATAGTCC |
ATCCTGGCTG |
GGTGCGGTGG |
CTCACGCCTG |
TCATCCCAGC |
ACTTTGGGAG |
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| 1601 |
GCCGAGGCGG |
GTGGATCACC |
TGAGGTCAGG |
AGTTTGAGAC |
CAGCCTGGCC |
AACATGGCGA |
AACCCCGTCT |
CTACTAAAAA |
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| 1681 |
TACCAAAAAT |
TAGCCGGTCA |
TAGTGGTGGG |
CGCCTGTAAT |
TCCAGCTACT |
CGGGGGGCTG |
AGACGAGAAT |
TGCTTGAACC |
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| 1761 |
CGGGAGGCGG |
AGGTTTCAGT |
GAGCCGTGAT |
CGCGCCACTG |
CACTCCATCC |
TGGGGAAGAA |
GAGCAAAACT |
CCGTCTAAAA |
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| 1841 |
AAAAATTGTG |
CAGTTTGAAA |
TTGTATTTCA |
TGTTATGTTT |
TATCTCAATA |
CAACATTTGC |
AGTTGTGAAA |
AAAAATTGCA |
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| 1921 |
CATTCTCAAC |
TCCTCGGGAT |
GGAGCAGTAA |
AGCCCCTCAG |
TAAATCTTTT |
TTTTTTTTTT |
TTTTTGAGAC |
CGAGTTTCGC |
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| 2001 |
TCTTGTCACC |
CAGGCTGGAG |
CGCAGGGGCG |
CGATCTCGGC |
TCACTGCAAT |
CTCCGCCTCC |
TGGGTTCAAG |
GGATTCTCCT |
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| 2081 |
GCCTCACTCT |
CCCGAGTAGC |
TGGGATTATA |
GACGCCCACC |
ACCACGCCCA |
GCAAATTTTT |
TGTATTTTTA |
GTAGAGACAG |
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| 2161 |
GGTTTCATCA |
TGTTGGGCAG |
GCTGGTCTCA |
AACTCCTGAC |
CTCTGGTGAT |
CCACCTGCCT |
TGGCCCCCCA |
AAGTGCAGGG |
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| 2241 |
ATTACAGGCC |
TGAGCCACCG |
CGGCTCGTCA |
AGTGAATCTT |
GATTCCAGAA |
AGATCTGTTT |
TAAGTCTCTA |
GTCTGGAAAA |
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| 2321 |
TGCAGTGGGA |
GTCTTTAGGT |
GGTTTGTGAC |
TTGCAGTTAA |
GGAGACCGTG |
GCCTGAGCAC |
TGGCCCCTTT |
TTCTTCTTTC |
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| 2401 |
ATCTCTCTCC |
AGGAACTGAG |
CATGGAATGT |
GGCCTCAACA |
ATCGCATCCG |
GATGATAGGG |
CAGATTTGTG |
AAGTCGCAAA |
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| 2481 |
AACCAAGAAA |
TTTGAAGAGG |
TAGGTTTATC |
CAGTTGAGCT |
ACTAGAGAGA |
GGCACGTAGA |
CTATTCAGAG |
CCTGAGTTTG |
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| 2561 |
CTTTTTTTAG |
GAACATGGTT |
GACAGCTGAC |
TGCCGATGAT |
CTGGTTTGCA |
CTTTTTTTTT |
TTTTTTTTTT |
TTGAGATGGA |
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| 2641 |
GTCTTGCTCT |
GTCGCCCAGG |
CTGGCACAAT |
CTTGGCTCAC |
TGCAGCCTCT |
GCCTCCTGGG |
TTCAAGCAGT |
TCTCCTGCCT |
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| 2721 |
CAGCCTCCTG |
AGTAGCTGGG |
ATTACAGGCA |
CGCGCCACCA |
CACCCGGCTT |
TTTGTATTTT |
TAGTAGAGAC |
GGGGTTTCGC |
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| 2801 |
CATGTTGGCC |
AGGCTGGTCT |
TGAACTCCTG |
ACCTCGTGAA |
CCATATGCCT |
CAGCCTCCCA |
AAGTGCTGGG |
ATTACAGGCG |
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| 2881 |
TGAGCCACTG |
CGCCCAGCCA |
GTTTGCACTG |
TTTTAGGGGA |
ATTTAGCTTT |
CATCGTAGTG |
ATGGGGAAGC |
TACTGGAAAT |
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| 2961 |
GCCCCGAATA |
CAACCTTGAG |
GGACCAATCA |
AGCGTGGAAA |
TGGGGAGCAA |
AGGGATTAGG |
CTTTTCTAGC |
AACACCAGAA |
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| 3041 |
AGGATTTCTA |
TGCCGAGCGG |
GGGTGCGGGG |
GCTTATGCCT |
GTAATCCTAG |
GACTTTGGGA |
GGCCGAGGTG |
GGTGGATCAC |
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| 3121 |
GAGGTCAGGA |
GTTCAAGACC |
ACTCTGGCCA |
ACATGGCGAA |
ACCCCGTCTG |
TACTAAAAGA |
TGATGAGCCG |
GGCATGGTGG |
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| 3201 |
CACATGCCTG |
TAATCCCAGC |
TACTTGGGAG |
GCTGAGGCAG |
GAGAATCGCT |
TGAACCCGGG |
AGGCACAGGT |
TGCAGTGAGC |
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| 3281 |
CGAGATCGCC |
CCACTGCACT |
CCAGTCTGGG |
TGACGGAGCA |
AGACTCTGTC |
TCAAAAAAAA |
AAAAAAGGAA |
GAGTTTGTAG |
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| 3361 |
TGGCTGATAG |
AAACGCATGC |
TCACTCGCTC |
TCTCCTGTTA |
CAAGTTCAGG |
CCAAGAAAAA |
TCAAGAAAGG |
GTTTGTTCCA |
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| 3441 |
CAGAGAACAA |
TCCTAGGCAC |
GCTGGTCTTG |
GTGCCATTTT |
GGGAGGGTGA |
CTGGTCGGTG |
GTATTGGGCG |
ACCTCACGGA |
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| 3521 |
CATAGAAATA |
TTTATTTTGG |
GCAAACATTG |
CCAGACTTTC |
CTGATGACTT |
GTGGACAGGA |
CAGGAAGTGG |
TCATTTTGGG |
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| 3601 |
AGTGCAGGTT |
GCTGGTAGAG |
CACCTGAGGG |
CTCTGCCCTT |
GCCTTGCCCA |
GCATTTGTGT |
GTGGGAGAGC |
AGTGAGACCT |
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| 3681 |
GGACCTCTCA |
TGCTCAGATC |
TGCTAAGAGG |
AGAGTGATTG |
CTACCTCTGC |
AGCAGCTCAT |
CTGAAACGTG |
CTGGCCGTAC |
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| 3761 |
GCTACCAAAG |
ATAGGTGTAA |
AGAACAGGTG |
TCCTTAGCCG |
GGCGCAGTGG |
TTCACGCCTG |
TAATCCCAGC |
ACTTTGGGAG |
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| 3841 |
GCCAAGGTGG |
ATGGATCACC |
TGAGGTGAGG |
AGTTCGAGAC |
CCGCCTGGCC |
AATGTGGCAA |
AACCCTGTTT |
CTACTAAAGA |
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| 3921 |
TACAAAAATT |
AGCTGGGCAT |
GGTGTCGGGC |
ACCTGTAATC |
CCAGCTACTT |
GGGAGGCTGA |
GGGAGGAGAA |
TCGCTTAAAC |
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| 4001 |
TCAGGAGGCA |
GAGGTTGTGG |
TGAGCTGAGA |
TTGTGCCATT |
GCACTGCAGC |
CTGGGCAACA |
GAGCAAGACT |
GTCTCAGAAA |
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| 4081 |
ACAAAAAAAA |
GAACAAGCGT |
CCTGCATCCT |
GTTCTGAAAG |
TTGTTTGTGT |
GGGTACGGGG |
CAGCCTGTGA |
GTGGATAAAT |
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| 4161 |
AGGCCTCCGA |
GGCTGGGATG |
GTCCCGGGCC |
CTGTGTCCAC |
GGATCTTTGC |
AGCTCAGGTT |
GCAACGGTAA |
GAGTATTGTC |
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| 4241 |
AATGAGACAA |
AGGAGGTGAG |
AGTGCCAGTT |
GTCTGAATTG |
GTTGGGATGT |
TGGTCAGATG |
ACATCTAAAA |
GAACACGGCC |
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| 4321 |
ATTTTGTTAT |
TATTTGGTTA |
GAGACAAGGT |
CTCACTCTGT |
CACCCAGGCC |
GGGGTGCAGT |
GTCACAATCA |
TGGCTCACTA |
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| 4401 |
CAGCCTCAAC |
CTGCCAGGCT |
CACGTGATCC |
TCCTACTTTA |
GCCTCTCAAG |
TAGCTGGGAC |
TACAGGCATG |
CAGCACCACG |
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| 4481 |
CCTGGCTAAG |
TTTTGTATTT |
TTTGTCGTGA |
CAGGGTCTCA |
CTGTGTTGCC |
CAGGCTAGTC |
TGAAACTCCT |
GGGCTGACGT |
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| 4561 |
GACCCTCTCC |
CCTCTGCCAC |
CCGAAGTGCT |
GAGATTACAG |
GTGTGAGCCA |
CCGCACTTGG |
CCAGAACACG |
GCCATTTTAG |
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| 4641 |
TTCCCCTCCT |
TAGAGGAGTA |
AGGCCAGGAA |
TGAGCCTGTG |
GTCTGAAAGC |
CGTGGCTGTT |
GGTTAATGTG |
GAGAAGGGAA |
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| 4721 |
GGTGGTGAGA |
GCCAGCCCAA |
ACCCCTGCCG |
AGTGAGACTG |
ATTCTGGCAG |
CTTTAGGGAG |
CAGGGATGAG |
CCCCTCACAG |
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| 4801 |
GCTGGGTGGT |
AGTTAGAGGA |
GGCAGATTTC |
AGAAGGCCAC |
GCAGCGCTCT |
TTCTCAGCAG |
GTCAGGCAGG |
CAGCAGAGGT |
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| 4881 |
CGGGCAGGGG |
CATGGGGTCG |
AGGGCCCGAT |
GCTGGTGTGT |
TCACTAGAGG |
AGAGCCACAA |
GCAGGGATTC |
TGGGTCAGGT |
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| 4961 |
GCAGGCCTAG |
GGCTTAGTGT |
GCACTTGTGG |
TTCTGAGACT |
GTCCCATGAC |
TTCCTGCCAG |
CATTCCGGCA |
GCTCTAGTGG |
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| 5041 |
GACTCCCTCC |
TGGTCCAGGT |
GAGGCCACCA |
TTGCTGCCCT |
GGCTTGCTGC |
TGTCCTCTCA |
GCCCCCAGTC |
TGTCACCTGG |
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| 5121 |
TGGGAGTTAA |
AGGGACCTGC |
TGGGGTTTGA |
GGAAGCTCTG |
AGCCGTTCCC |
TGTACGAAGC |
CTGTGGTCAT |
CTCAGGCTGC |
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| 5201 |
AGGAGACACA |
GGAGATACGA |
GCTTTGGAGG |
TGGGGCTCTC |
AGTCACAAGC |
CCCCGTTGTT |
CCTCCCTGTC |
CTCCGCTCAC |
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| 5281 |
GGCACTGCTC |
CAGTTGCCGG |
GGCCAGGGTT |
CTTGGAGAGC |
ACATCCTCAC |
CGCTGTCCCC |
TCTGCTGGTG |
ACAGCACGCA |
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| 5361 |
GTGGAAGCAC |
TCTGGAAGGC |
GGTCGCGGAT |
CTGTTGCAGC |
CGGAGCGGCC |
GCTGGAGGCC |
CGGCACGCGG |
TGCTGGCTCT |
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| 5441 |
GCTGAAGGCC |
ATCGTGCAGG |
GGCAGGTAAG |
GCCCAGGGCG |
ACGCTGGGAT |
GGGTGACGTC |
AGGCTGCCCA |
CTGACTGTCC |
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| 5521 |
TGTCCCTGCT |
GGGCCGTGTT |
TGGACTCCTG |
CCTCGGTGAG |
TTGCTGGGCA |
CAGGGTCTAG |
GGGCTGATGG |
GCTCTGGAGC |
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| 5601 |
TGGATGGCCT |
GTGGGGTCTC |
CTGGTGTCAT |
GAGGTCTGTG |
TGACCGTAGG |
CACTGCCTCC |
TCGCCTGTAA |
ACAGATGGTC |
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| 5681 |
ACTGCACCTT |
CCTCTTATGG |
GATGTTCTGG |
GGATCATATG |
AGGCAGTTCT |
CGCAGAGTGC |
TGAGATCGTA |
CCTGGCAGCT |
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| 5761 |
GGTGTGGGGC |
TACGGTGTTG |
TTTTGCCCTT |
GCACCCTTTC |
GGGGCCACTC |
CCCTGCTCAC |
TGCATTCCAT |
CTGTGCTGGT |
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| 5841 |
CTTGGCTGAC |
CCTGAACACC |
CAGGCCTCTT |
GGTGTTCCTG |
CCTCCCCTGG |
TCGGCCACTT |
CTACTCCTTC |
ATGTCCCAGC |
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| 5921 |
TGCTCAGAAG |
GGCCGTCCAC |
TCTCACAGGC |
TCTCCTGGGT |
TTCCCCCACT |
CAGGCCTTGT |
CCTCAGTCTC |
TGAGCACAAG |
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| 6001 |
GCTGTCTGCC |
CTGCACCGAG |
TGCAGGGGTC |
GGGCAGGAGC |
TGTGTCATCC |
CCTGCTCTGC |
GCCACCCGCT |
GTGCCAGGTC |
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| 6081 |
CCGACACACA |
GCAGTTGCTC |
CCCATACGCC |
GCTCTGCGGT |
CGGCCGGTGC |
ATCCGGCCCC |
CTGCCCTGTA |
CAATGCTGAT |
|
| 6161 |
GCTGCAGACC |
TGTCTCTTGC |
AGGGCGCCTC |
TGTGGGAAGG |
AGAGGGGTCC |
AGGGCTGGAG |
TCCGGGTGCC |
CCTGCACTTC |
|
| 6241 |
AGGGACTTCT |
TGGCAGCCGT |
GTGGGCGACG |
CTGGCAGGCT |
CTGCTGATCC |
TGTGGCTTTT |
GTCTTTAGGG |
CGAGCGTTTG |
|
| 6321 |
GGGGTCCTCA |
GAGCCCTCTT |
CTTTAAGGTC |
ATCAAGGATT |
ACCCTTCCAA |
CGAAGACCTT |
CACGAAAGGC |
TGGAGGTTTT |
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| 6401 |
CAAGGCCCTC |
ACAGACAATG |
GGAGACACAT |
CACCTACTTG |
GAGGAAGAGC |
TGGGTGGGTG |
CCACCTTGGG |
TTGGAGGTTT |
|
| 6481 |
CTCTGGCCTT |
GACGATCAAG |
TGTAACCTGG |
ATGGGAAGGA |
CCTGGGGCTG |
GGGAGGGGCT |
GCCGTTCTCA |
GGGATGGCCT |
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| 6561 |
GCAGCGGGTA |
TGCCCACCCT |
GCTTCATGCA |
CCTGGGCTCA |
CCTGCGTGGC |
CGGAGTGCCC |
CTGAGGCACG |
TGTTAAAAAT |
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| 6641 |
GCAGAGTCCT |
GGCCTTCACC |
CCAGACCTGC |
TGACTGTGAG |
TCTCTGGGGC |
TTGGGGCCTC |
CGAACACCTC |
TGCAACGGCA |
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| 6721 |
GGAGCTGGGC |
GAGTTCTGTC |
ACTGGGAGGT |
GGTGCTGCTG |
ACTTGGTCTC |
AACCGGAGCG |
TACTGGTCCC |
GTCTTCCTCC |
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| 6801 |
TCCTTTCTCC |
ACTTTGTGGA |
CCTTCCTCCT |
GCCATCCTGT |
GGTGGGAGGT |
TTCCATTAGT |
CTTGGGTCTC |
TGTGTCATGA |
|
| 6881 |
TTCTGGGAAG |
TAGAGAAAGA |
GGAGGAAGAG |
ATCGGTCTGA |
CTCTGGCTTT |
GCTGTTCTGT |
CGCCCAGAAA |
AGGGCCTCAG |
|
| 6961 |
TGGCTGGGCT |
GCCTGCAGGA |
CAGGTGCCGG |
CCAGGTGCCT |
ACCGTCAGGT |
TTCCTGTCTG |
AGGTGACGTG |
GCCGGCAGCC |
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| 7041 |
AAGTGTGCAC |
ACGTCTCCTC |
CGAGCCACTC |
TCTGCTGGGG |
GTGGGGAACG |
CCCAGGAGTC |
TGGTGATGTC |
GGCGTCTCCC |
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| 7121 |
AGCCTCGGGT |
TGGGCCCTGA |
GTGTACGGCA |
TACACACTTC |
TGCTGCCGCC |
TCGGCACAGA |
CCCTCTGTGC |
AGCCCCAGGG |
|
| 7201 |
GCGGTAGATC |
CTAGTGTCCG |
TGCGTAGCCG |
GCCTGCCCTG |
GGCTCCCCTG |
AGCCTCTTCG |
GGCCCAGTGC |
GTGGTCTGTC |
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| 7281 |
TGTTGCTGCC |
GGGGGACTGA |
TGATGGGGTT |
TCTGGCAGTG |
ACGGGTTTGG |
ACACACTGTC |
CTGCGGCGGG |
AGGGGGAGGT |
|
| 7361 |
GAGTGGGAGA |
TGTAGATTCG |
GCGTCCTCGC |
AAACTGCCGC |
CGCTTCTCCC |
CCAGCTGACT |
TTGTCCTGCA |
GTGGATGGAT |
|
| 7441 |
GTTGGCTTGT |
CCTCGGAATT |
CCTTCTGGTG |
CTGGTGAACT |
TGGTCAAATT |
CAATAGCTGT |
TACCTCGACG |
AGTACATCGC |
|
| 7521 |
AAGGATGGTT |
CAGTAAGAAA |
AGAATTGAGA |
TCCTGTTCTG |
ATAATGGTCC |
TAAGTTCAGC |
TCCGCAGTGA |
ATAAAGTTGA |
|
| 7601 |
AACCACCAAA |
AAAATAGAGG |
TTGGGCTGGG |
CACAATGGCT |
CACGCCTGTA |
ATCTCAGCAC |
TTTGGGAGGC |
CGAGGCAGGC |
|
| 7681 |
GGATCACGAG |
GTCAGGAGTT |
CGAGACCAGC |
CTGGCCAACA |
TGGTGAAACC |
CTGTCTCTAC |
TAAAAATACA |
AAAATTAGCC |
|
| 7761 |
GGGCATGGTG |
GTGGGAGCCT |
GTAATCCCAG |
CTACTCAGGA |
GGCTGAGGCA |
GGAGAATTGC |
TTGAAACCGG |
AAGGCAGAGG |
|
| 7841 |
TTGCAGTGAG |
CGGAGATCGT |
GCCACTGCAC |
TCCAGCCTGG |
GTGAAAGAGC |
AAAACTCCAT |
CTCAAAAAAA |
AAAAAAAAAA |
|
| 7921 |
AAGAGAAGTA |
CGTAGCTATC |
TTCTGTTTAG |
CTCTCATCTG |
ATGTCTTGGT |
TATCTTTTTG |
TTGTTTGTTT |
AGAATGTTGC |
|
| 8001 |
ATGAGCTCTG |
TCTCACTCAT |
GCTGAACACC |
CAGCACCGAG |
AGCAGTGGCT |
GGCGCACAGC |
AGGCACCTGA |
GTGCTTGTTG |
|
| 8081 |
GGTGGGTGGG |
ACCCCCAGGG |
AGGATGAGCC |
ATGCGTGTTA |
TTGACGTCAT |
AGAGTGACTA |
GACCACAGCC |
CGTGGTGGCT |
|
| 8161 |
CGGCCATCCA |
GGCAGTGCTG |
CCGGGACTGA |
GCTCGGTGCT |
CCCTGCAGGA |
TGATCTGTCT |
GCTGTGCGTC |
CGGACCGCGT |
|
| 8241 |
CCTCTGTGGA |
CATAGAGGTC |
AGTGCCTCCC |
CTCCCCAGGG |
CCGGCCCATT |
TCACCCTGGT |
TTCTGGGAGG |
CTGGGGCTTG |
|
| 8321 |
GGGGTTGAGC |
CCTGTGTGCC |
ACCTGCTGGC |
TGTGTAGCCC |
TGGGCAAGCT |
GCTCGGTCTC |
TCTGAGCCTC |
AGGAGTCCCC |
|
| 8401 |
CATGTAAGTC |
AGGATAGCCG |
GGCGCCTCCA |
TGTGGAGATG |
TAGCTCAGGG |
TGGATGACAG |
CATCAATGAC |
CCACAGTGAC |
|
| 8481 |
AGGGACGTCA |
GGTGCTTCCC |
ACATGCCCGC |
TTGCCCTGTG |
GCTTGGAGAG |
AGGGTGCCAT |
GGCAGCGGGG |
AGAGGTGGCA |
|
| 8561 |
GCGCAGGCTG |
AAGGAGGTGG |
GAAGGAAGCC |
TGGGTGTCCT |
CTCCTGTGGG |
GAGGAGCTGG |
GGTAGGACGG |
GCGTGAGCCG |
|
| 8641 |
TCTCCCTCTC |
CACCAGGTCT |
CCCTGCAGGT |
GCTGGACGCC |
GTGGTCTGCT |
ACAACTGCCT |
GCCGGCTGAG |
AGCCTCCCGC |
|
| 8721 |
TGTTCATCGT |
TACCCTCTGT |
CGCACCATCA |
ACGTCAAGGA |
GCTCTGCGAG |
CCTTGCTGGA |
AGGTGGGGTT |
TCTGAAACTG |
|
| 8801 |
CTCTGGAAGG |
TTCCTGAGAG |
CACATGGATG |
GGACAAGGGC |
CATCCTGTCT |
CCCATGAATG |
GTTGTCTGAT |
TCTTGGGGTG |
|
| 8881 |
GCCAGACAAT |
GGCCTGTTGA |
GGGACGGCCA |
GTGTCATTTT |
CCCAGGCAGT |
TGAGCTGAGG |
TCAGGGTTTT |
GGTGGCATTT |
|
| 8961 |
TGAGAACCCT |
GCTGCCTCTG |
TCTTTGGGAG |
GAGATGGTGG |
CGAGCTGGCC |
GGACCTTGGG |
TGGCTATAGG |
GCAGCAGCCA |
|
| 9041 |
GGCGGGGCCA |
GCAGCGGGAC |
TGGGGCTGGG |
GGCAGGGCTT |
ATGCCTGCCA |
GCCCCTGACA |
CGCATTGTGT |
CTCGCAGCTG |
|
| 9121 |
ATGCGGAACC |
TCCTTGGCAC |
CCACCTGGGC |
CACAGCGCCA |
TCTACAACAT |
GTGCCACCTC |
ATGGAGGACA |
GGTGAGTGTG |
|
| 9201 |
GTGGGTGGGG |
CGCAGGGCAG |
TGGAGGCCAG |
CACAGCCCTC |
GGGGCAGCTC |
CAGTGTCCCT |
TGCCAAGCAC |
ACACTGGCTT |
|
| 9281 |
AGAGAGTCCT |
TGTCCTCTCG |
GGCAGCTGTT |
CCAGAGGCTG |
CCACTAGAGC |
GAGGCCCATG |
ACTTCTAGGA |
TCCAGCCCCT |
|
| 9361 |
GTCCTCTCCT |
TCCTCTGTCA |
GTTCAACAGA |
ATATCCACAC |
CCAGCTCAGT |
GCCTGCCCCA |
TGCTCGGACG |
TCCTCCAGCG |
|
| 9441 |
GTGCTCCCCA |
ACTACTTAGC |
CTGTTACAAG |
GCGAGGCTCG |
GGGTCTTGGC |
TTGACGTTGC |
CCTTGCCCTC |
ACCCCCACAG |
|
| 9521 |
CCAGGCTGTG |
GCCACTTTTG |
TTGCTTTAGC |
CATTAGAGAT |
GGCTCAGCTC |
TGCCCACACC |
CTGGCCTCCC |
ACCCATGCTG |
|
| 9601 |
CCAGCTCCCC |
CTCCTGCTCT |
CCTGTATCCA |
TCCGCGCCTC |
CTGAAGCCCA |
CTCCATGCAG |
CACCCGGGTG |
GCCTTTTTCT |
|
| 9681 |
GACACAGATA |
TGTCGGTGTC |
ACCCTTTGCT |
GGAAGCCAGG |
TGGTTCCCAG |
CGCCCTTGGG |
ATGTAGGCTT |
CTCCTATGGA |
|
| 9761 |
ACCAGGCCCT |
GGGGCCAGCC |
CTGCCTCAGC |
CCTGCATCTC |
TCCCAGCCCT |
GCCTCGGCCC |
CTGCATCTCT |
CCCAGCCCTG |
|
| 9841 |
CCTCGGCCCC |
TGCATCTCTC |
CCAGCCCTGC |
CTCGGCCCCT |
GCATCTCTCC |
CAGCCCTGCC |
TCGGCCCCTG |
CATCTCTCCC |
|
| 9921 |
AGCCCTGCCT |
CGGCCCCTGC |
ATCTCTCCCA |
GCCCTGCCTC |
GGCCCCTGCA |
TCTCTCCCAG |
CCCTGCCTCG |
GCCCCTGCAT |
|
| 10001 |
CTCTCCCAGC |
CCTGCCTCGG |
CCCCTGCATC |
TCTCCCAGCC |
CTGCCTCGGC |
CCTGCATCTT |
TCCTTCCCTC |
CATCCTTGGA |
|
| 10081 |
ACCAGGCCCT |
GGGGCCCAGC |
CCTGCCTCAG |
CCCTGCATCT |
CTCCTAGCCC |
TGCCTCAGCC |
CCTGCATCTC |
TCCCTCCCTC |
|
| 10161 |
CTCCCGTAGA |
ACCAGGCCCT |
GGGGGCCAGC |
CCTGCCTCAG |
CCTGCATCTC |
TCCCAGCCCT |
GCCCCACCCC |
CTGCATCTCT |
|
| 10241 |
CCTTTCCTCC |
ATCTTGCCTT |
CTCCCCTCCA |
CCAAGGGCTT |
GTGCATGCCC |
TGATTCCTCT |
TGCCAGCAGG |
TTCTTCCACC |
|
| 10321 |
TTTGCCGAGT |
TACTCTGTTT |
ACTGAGGTCT |
TAGCGTGGTC |
ACTGACTCCC |
CCACCTCCCT |
GAGTAGTTTT |
TGCTGTGGCT |
|
| 10401 |
TTCCTTCTTG |
GCTGTGATTG |
GAGGAAGAGA |
TTTTGCGTTT |
ACCTGGGAGA |
TTATGTGGCT |
GGCGCCTGTC |
TCCCCCAGAC |
|
| 10481 |
TGCGAGGCTG |
TGGGCCATCC |
CTCTTGCCTG |
CTTCCTGTCC |
CTGGCATGAC |
CTGTAGCTCA |
CAGCGTGGTC |
AGCAGTGATG |
|
| 10561 |
GGCTGCCGCC |
TGTGCGCAGG |
AGTGAACAAG |
AGTGTTACTG |
CTGGCCTCTG |
TTCCCTGCCC |
TTCCCCAGCG |
GTGCTCCTGC |
|
| 10641 |
CCCCCCCAAG |
CACAGGGACC |
TCTGGGGCTG |
CTGCAGGAGC |
CTCGGCAACC |
TCACACATCC |
ATGGCGGACC |
CTGGGACAGG |
|
| 10721 |
GCCCTGCTCA |
CATTCCGTCT |
CTCTGGGGAA |
CACTTTTAGA |
GCCTACATGG |
AGGACGCGCC |
CCTGCTGAGA |
GGAGCCGTGT |
|
| 10801 |
TTTTTGTGGG |
CATGGCTCTC |
TGGGGAGCCC |
ACCGGCTCTA |
TTCTCTCAGG |
AACTCGCCGA |
CATCTGTGTT |
GCCATCATTT |
|
| 10881 |
TACCAGGTAA |
GGCGGTTTCT |
GTGTGCAGTG |
AGCTGGCAGG |
AACGGGAGAG |
CTCCCCTCAC |
GCCTGCCCAC |
CCATCCCACT |
|
| 10961 |
GGGGGTCCTG |
CTGCGGGGGC |
TGCGGTGGCA |
TTTCTAGGCC |
TTTCCAGGCA |
GTTGCTTTGC |
AGCTGGGGGT |
GAGGTTTGGG |
|
| 11041 |
GCCCTTTGTA |
GGCTTTAGTC |
TTTTTTTTTT |
TTTTGAGAAG |
GAGTTCTGCT |
CTTTCTGCTT |
GGCTGACTGC |
AATCTCCGCC |
|
| 11121 |
TCCCGGATTC |
AAGTGATTCT |
ATTGCCTCAG |
ACTCCTGAGT |
AGCTGGGATT |
ACAGGTGCCT |
GGTACCATGC |
CTGGCTAATT |
|
| 11201 |
TTGTGTTTTT |
AGTAGAGACG |
GGGTTTCGCC |
ATGTTGGCCA |
GGCTGGTCTC |
GAATTCCTGA |
CCTGAAGTGA |
TCCACCCATC |
|
| 11281 |
TCAGACTCCC |
AAAGTGCTAG |
GATTACAGGC |
GTGAGCCACC |
ATGCCTGGCC |
AAAGGCTTTT |
TTCTCTCTCT |
CTTTTTTTTT |
|
| 11361 |
TTTTTTTTTT |
TTGAGACAGA |
GTTTTACTCT |
TGTTGCCCAG |
GGTGGAGTGC |
AATGGTGCGA |
TCTCGGCTCA |
CTGCAACCTC |
|
| 11441 |
TGCCTCCCCA |
GTTCAAGCCA |
TTCTGCCTCA |
GCCTCCTGAG |
TAGCTGGGAT |
TACAGGTGCC |
TGCCACAGTG |
CCTGGCTAAT |
|
| 11521 |
GGTTTTTTTT |
TTTTTTTTTT |
TTTTTTAATG |
GGACAGAGTT |
TCGCTCTTAT |
TGCCCAGGCT |
GGAGTGCAAT |
GGCGCGATCT |
|
| 11601 |
TGGCTCAGCG |
CAACCTCCGC |
CTCCCAGGTT |
CAAGCCATTC |
TCCTGCCTCA |
GCCTCCTGAG |
TAGCTGGGAT |
TATAGGCATG |
|
| 11681 |
GGCCACTACA |
CACAGCTAAT |
TTTTTATTTT |
TAGTAGAGAC |
TGGGTTTCTC |
CACATTGGTC |
AGGCTGGTCT |
CAAACTCCCG |
|
| 11761 |
ACCTCAGGTG |
ATCCGCCAGC |
CTCAGCCTCC |
CAAAGTGCTG |
GAATTATAGG |
TATGAGTCAC |
CGTGCCCGGC |
CAAGGCTAAT |
|
| 11841 |
GTTTTGTATT |
TTTATTAGAG |
ATGGGGTTTC |
ACCATGTTGG |
TCAGGCTGGT |
CTTGAACTCC |
TGACCTCAGG |
TGATCCACCC |
|
| 11921 |
GCCTTGGTCT |
CCCAAAGTGC |
TGAGATTATA |
GGCATGAGCC |
ACTGCGCGCA |
GCCCAAAGGC |
TTTATTCTCA |
AGCAAACCTT |
|
| 12001 |
ACATCTTGCG |
AGTTTCACCT |
TCTGGAGTTG |
GCAGTGGAGG |
GGTGAACGCT |
GCCTCGGGGG |
TAGCCGTTCT |
CTTGCTGTTG |
|
| 12081 |
GCGGCTCTGT |
TTTGTCAAGT |
GCTGGTCTTG |
TCCTGTCTCT |
GCAATGACGC |
CGTGGCACAG |
ACGCTGGTGG |
TACAGCTTCA |
|
| 12161 |
GTTTCCGCAG |
TGCCCCGTGA |
TGACAGCGCT |
TTTTGTGTCC |
GTCCTCGTTC |
TGTGCTCACA |
GCTCCCTGGA |
GGGTGGGGCG |
|
| 12241 |
ATCACGTCGT |
CCTGGTTTTA |
TAGTGATGAG |
CTGCGGTGTG |
GGTCACAGGG |
CTCTCCTGAT |
CCTCTGCTCT |
TCCTGCTACC |
|
| 12321 |
CCCCTCCCCG |
TAGGGGCGGT |
GGGGGGATGT |
TGTCTTTGTG |
CACAGCTTGC |
AGCCGAACTC |
AGGGCAGCTT |
TCAGTTGCTG |
|
| 12401 |
CTGGGCTGGC |
CCACCGGGTG |
CCCAGGATTC |
AGTTGCTGGT |
CTGTCCGAGT |
CAGGGACTTT |
GCAGGCAGGC |
ATGGGGGTGG |
|
| 12481 |
GGCCCGTCTG |
GGTCCTGACT |
GTGCTGGAGC |
ATGTAGAAAC |
CCCTCCTGGG |
CGCCCCACCT |
GCTGTTTCTG |
CGGCCCCTGA |
|
| 12561 |
TAAACGTGTG |
GTGGGCACTG |
CGCGCTCAGG |
CGTGCTACTC |
TCGGTCCCAA |
GGGTGACTGG |
GAGGGCGTCC |
CACAGCAAGC |
|
| 12641 |
AAGCAGCTCT |
GACCCTGTGT |
GCTGGCCGGG |
CTCGTGTTCC |
AGGCCATGGC |
ATGTCCGAAC |
GAGGTGGTGT |
CCTATGAGAT |
|
| 12721 |
CGTCCTGTCC |
ATCACCAGGC |
TCATCAAGAA |
GTATAGGAAG |
GAGCTCCAGG |
TGGTGGCGTG |
GGACATTCTG |
CTGAACATCA |
|
| 12801 |
TCGAACGGCT |
CCTTCAGCAG |
CTCCAGGTGG |
GGTGGGGGCA |
GGAGCTCCGG |
GGAGCACCGG |
GAACCCAGAC |
AGGCAGGCTC |
|
| 12881 |
GGCCCACTCA |
GAAGATGGTA |
CCTTGGGCCC |
CATCTCTGGG |
GGTCCCGCAG |
AGACTGCCAG |
AACCGTGTTC |
TCTGGTGATT |
|
| 12961 |
CGCAGTGGCG |
CTCATCCACC |
TTCCACCGGA |
GACAGGTCTG |
ATTTTTCCAG |
ACGTGGTGCA |
TCGTTTAGGC |
CCCAGACAGG |
|
| 13041 |
AATATGCAGT |
AGGTGAGCCG |
GGGCTGGGCC |
AGTGCTGTCC |
ACAGTCCGCA |
GAGTGACCTG |
CAGGCCGCCT |
TCGTGGCCTG |
|
| 13121 |
AGTGGGCCCC |
GGCACAGTTC |
CCAGAGGGAT |
GCCAGTGTGG |
CTTCCGCATG |
ACTTTGGAGG |
ACCGCATTAG |
TCGAGTCTGT |
|
| 13201 |
TAACCACAGC |
TTTAAGGAGG |
ACTCCACGGC |
CACACGGGCT |
CATCAGCATA |
GGGGCCCTGG |
GGAGGCGAGG |
CTAGTATCCA |
|
| 13281 |
GCAGCCTCAG |
GGCTGTGCCT |
TTTCCTGGAG |
CCTGGGGCGG |
GTGATGTACA |
GGAGGCCAGG |
CAGCAGAAGG |
GAGGCCGGGA |
|
| 13361 |
CTTCGCCGGG |
ACTTAGCAGG |
GACTGAAGTC |
CTCTCAGAGC |
CTGTCGCTGG |
GCCAGAGCAT |
TGCCCCCGAC |
CGCTGGTGGC |
|
| 13441 |
AGTGGCAGAG |
GTCATAGCCT |
GGGGCTTCTA |
AAAGAGGCTG |
GACCTGGGAG |
AGGCAAGAAA |
GGCTTGTAGT |
TGTGGCTACT |
|
| 13521 |
CTTGGCCCTC |
CTGCCCGAGC |
TTCCTTCTTG |
GCCCAGCTGC |
ATGGGCACAG |
CCAAGATTCC |
TTGGGGGGTG |
GGGTACGGGC |
|
| 13601 |
AGGAACAGCA |
GCTGCCATCA |
CAGCCACTGT |
GGCCCCTTGA |
GAGGATCTGG |
GGGGTGTCCT |
GGGCCACGTG |
GGTCAGGGTG |
|
| 13681 |
GCCCCTGGAG |
AGGATCTGGG |
GGTGTCTCAA |
CCCATGAGGC |
CCGGAGCGGC |
CTCAGAGGGC |
TGGGGGCGTC |
TGTCCCCATG |
|
| 13761 |
CGGCCCAGAG |
CGGCCTGAGA |
GGGCTGAGGG |
TGTCTCCATG |
CGGTGGGTGT |
GTAGCGAGGC |
CTCTGGTGCC |
AAGTCCATGT |
|
| 13841 |
GGGGAGTGGA |
AGTCAGCCTG |
TGTCATCGTG |
CCTGGTACTG |
CAGACCTTGG |
ACAGCCCGGA |
GCTCAGGACC |
ATCGTCCATG |
|
| 13921 |
ACCTGTTGAC |
CACGGTGGAG |
GAGCTGTGTG |
ACCAGAACGA |
GTTCCACGGG |
TCTCAGGAGA |
GATACTTTGA |
ACTGGTGGAG |
|
| 14001 |
AGATGTGCGG |
ACCAGAGGCC |
TGTGAGACCC |
CCTCCTGGGT |
GGGGCCTTTG |
GGCTTTGGCT |
GGTGGGGAGG |
GGCCGGGTGC |
|
| 14081 |
TGGGTGAAGT |
GCAGCTTTCT |
GAGCCTCAGA |
AGCCAAGGGC |
CAGGTGGGCG |
CCTGCTTTCC |
AGGTTTCTGC |
ACTCGGCAGG |
|
| 14161 |
GAAGGCTGGC |
AGGCACAGCA |
CGTGTTTGGT |
AACAAGCTCG |
GGGCTAGCCC |
ACCCATCAGT |
TTCCTCCCAC |
CTGTGTGGAG |
|
| 14241 |
CAAGCTTCCA |
TCCGGCTCTG |
TAGAGTCCTG |
TGGCTCCCAG |
GCGGCCGCAG |
TCATTTTGCC |
AGGAACACTC |
AGCTTAGGGC |
|
| 14321 |
CCAGGCTTTT |
CCATGGGTTT |
GGACACAAGT |
CTTCCCCGCT |
GCCAGGAGTG |
CCTTTGTGTC |
TGGGCTGTGG |
GCTGCAGGCT |
|
| 14401 |
GTGAGGCGGC |
TGGGCTCTGA |
CAGCAAACCA |
GCCTCTCGAC |
CAGCAGCCCA |
GTGTGGAGAA |
GGAGAGCGCC |
GGAGGGGCAG |
|
| 14481 |
AGGGGCAACA |
CCGGCTCTTC |
TTTTGACAGG |
AGTCCTCCCT |
CCTGAACCTG |
ATCTCCTATA |
GAGCGCAGTC |
CATCCACCCG |
|
| 14561 |
GCCAAGGACG |
GCTGGATTCA |
GAACCTGCAG |
GCGCTGATGG |
AGAGATTCTT |
CAGGTAGGGG |
GTCCTCTGTA |
GCCTTGCCTG |
|
| 14641 |
GCACCTGGAG |
CCTGGCCCTG |
TCTCTGTCTG |
GGGCCCACCC |
GGGCTGGGTC |
TCAGGATGCC |
CGATGAGCAG |
GGCCCTCCCC |
|
| 14721 |
TCTGCCTCTG |
GAGAGCCCTG |
GCTCTGGGTG |
AGCAGGTGCT |
AGCTTGCTTT |
CCAGTCCAGC |
AGGACAGGTC |
CTCTCATGAC |
|
| 14801 |
GCCACTGGGC |
TCCCTCTTTT |
CGGGGGTCGT |
CTGGAGAGAT |
GCTCCCTGGG |
AAGCAGAGCT |
CTGTGCCCTG |
TGTGCCTGGC |
|
| 14881 |
CGCGGGAGGA |
CCCAGAGTCG |
GGCTGGCCTG |
CGCCAGGCAG |
ACGGGCTGGT |
GTGGGGCTGT |
GGCCGGGCAC |
TCCCCACCCG |
|
| 14961 |
CCCCAGCAGG |
CTGCCGTCCC |
GCAGGAGCGA |
GTCCCGAGGC |
GCCGTGCGCA |
TCAAGGTGCT |
GGACGTGCTG |
TCCTTTGTGC |
|
| 15041 |
TGCTCATCAA |
CAGGCAGTTC |
TATGAGGTGC |
GTGTCCAGGC |
GGCCGCAGCT |
GGGGGCTCAG |
GGCTATTTCT |
CCGTGGGCGG |
|
| 15121 |
GCTGTCTCTG |
TTGTGCACGT |
GCTCCCGCAG |
AGCCGGGCTC |
TGCCTGGGAC |
TTCGGTCCTG |
CCGGACCCTC |
TGCAGCCCCC |
|
| 15201 |
AGCGTGGTCT |
GTTTACCCCT |
GTTCATTCAC |
TGGCTTGCTC |
GTCCTGGGTG |
CCTCTGCCAG |
GCCTTGACAC |
GTGGCCAAGT |
|
| 15281 |
AGCAAGGAAG |
GCACAGTGCC |
TGCCCTCAGG |
GAGCTCCGGC |
CGGTTTTCAC |
CCAACACAGG |
AGCCTCTTAA |
AAATTCTGTG |
|
| 15361 |
TGAGTTCGTT |
TCAGCCAGTC |
TTGCATGGGG |
ACATTGTCTT |
CCGTTTCAGT |
CCTGACGTTC |
ACCCTGTGCA |
CCTGCGTGAT |
|
| 15441 |
CGCCAGCCCT |
GCCTGGTCTC |
TCCTCTGCGG |
GCTCTCCCTC |
TCCACTCCCT |
CCTCTGGGAG |
CTCTGTGGCC |
CCAGGCCCAC |
|
| 15521 |
CTTCCTTGAG |
AGACATTTGT |
GTGCCTGCCA |
GTCATACCCC |
TTTCCCAGGA |
GGCGCAGCTT |
AGGCTCTGAG |
GCTGTCCCTT |
|
| 15601 |
CCCACCGAAC |
TCCTCCCTGC |
AGCCTCGCAG |
TCCTGCCCTC |
CTGAGAGCTG |
CCCACTCTGC |
TCCTCTCCCC |
AGCGTCCACT |
|
| 15681 |
GTCCTTGAAT |
TGCCCTTTGC |
TGGGCATTGC |
GATCCCGCAT |
TCTGTCTGAG |
GGAGCTAAGG |
GCCTCCTGGA |
AGTTCCTCTG |
|
| 15761 |
GGTCCTCTGG |
CTTCTCCCAT |
CAGGGCTGGT |
CTTGTCCTGG |
TCTCTGTTCC |
TGTGGAACTT |
TTTACCTGCT |
TCTGTGAAAA |
|
| 15841 |
CTCACGCTGT |
CCTCAGCACA |
GCACGCACAC |
ACACGCATAT |
TCACGCATGC |
ACAGGCACAC |
ACGTGCACAT |
GCCCACGCGT |
|
| 15921 |
GCACACAGCC |
ACACACACCC |
TCACGCACAC |
ACGCACAGCA |
CCATGTGGGA |
GGGGTTCTCG |
GCTGTGACAG |
TGAAGGGCAG |
|
| 16001 |
GGCCTCACCT |
CGGCTGCTCC |
TTGTGAGTTG |
TGGGCCCCGT |
GTCTGTGCCC |
GGCCGCCCTG |
CGGTGCTCAC |
CAGCCTTCTG |
|
| 16081 |
AACGAGGAGC |
TGGACAGGAT |
CCCTGGAAGG |
GGCCCCGGGG |
TCTCTGAGTC |
GCGCTCAGCG |
GGTGCTTGTG |
CTCTCTGCCC |
|
| 16161 |
AGCTGTGCTG |
AAGTCCCGAG |
GGACATGTCC |
GCTGCTTGCG |
GGTCGGTTCC |
TGAGGAATTG |
GAAGTGTCAC |
GAGATGTGGC |
|
| 16241 |
CCTCGTTGGG |
CTGGCGCTCA |
TTGGCCTCCC |
TTGTGCCTGT |
GCAGGAGGAG |
CTGATTAACT |
CAGTGGTCAT |
CTCGCAGCTC |
|
| 16321 |
TCCCACATCC |
CCGAGGATAA |
AGACCACCAG |
GTCCGAAAGC |
TGGCCACCCA |
GTTGCTGGTG |
GACCTGGCAG |
AGGGCTGCCA |
|
| 16401 |
CACACACCAC |
TTCAACAGCC |
TGCTGGACAT |
CATCGAGAAG |
GTGAGAGCCG |
TTGTACCCGG |
GGCCGGGTGC |
TAGCGTGCCA |
|
| 16481 |
GAGCTCCGTG |
GGCAGCAATG |
GCCTCTGGGC |
CCTCTGTCCT |
CCTCTTCGAG |
TGACCGGATG |
GCTGTGTCCG |
TAGGTGAGGC |
|
| 16561 |
TCCCCTCCCT |
GCAGGGTGGG |
TGTCCCGAGG |
CCTGTGCAGG |
GCCTGCCACT |
GCTGGATTTG |
TGTCCTGACT |
GAAAGTCCTG |
|
| 16641 |
GACATGGGTG |
TCCTGTCACA |
CTCTGGGACA |
GCTGGGCTGG |
GCCTCCTGGA |
CCGACGCTGG |
AGCCCAGACC |
TGGGGCTGGG |
|
| 16721 |
GCTTTGGCCT |
GCCGTCCTCC |
CTGCCCAGCC |
AACAGCTTTG |
CTCTTTGATT |
TTCAGATGCA |
TTTTGGTTTC |
TGCACAGTCA |
|
| 16801 |
CTCGGGTATA |
AAGGGCATCT |
TTGCTTTTGA |
GCAATAAAGA |
TGAAGGCCGG |
GCACAGTGGC |
TCACGCCTGT |
AATCCCAGCA |
|
| 16881 |
TTTTGGGAGG |
CTGAGGCAGG |
TGGATTGCTT |
GAGTTCAGGA |
GTTCAAGACC |
AGCCTGGCCA |
ACATGGTGAA |
ATCCTGTCTC |
|
| 16961 |
TACTAAAAAT |
ATAAAAATTA |
GCTGCACGTG |
GTGGCGGGCA |
CCTGCAATCC |
CAGCTGCTCA |
GGAGGCTGAG |
GCAGGAGAAT |
|
| 17041 |
CGCTTGAACC |
TAGGAGGTGA |
AGGTTGCAGT |
GAGCCAAGAT |
TCTGCCACTG |
CACTCCAGCC |
TGGACGACAG |
AGCAAGACTC |
|
| 17121 |
TGTCTCAAAA |
AGAAAAAAAA |
AAAGGGCCGG |
GCACGGTGGC |
TCATGCCTGT |
AATCCCAGCA |
CTTTGGGAGG |
CCAAGGCAGG |
|
| 17201 |
CGGATCATGA |
GGTCAGGAGA |
TCAAGACCAT |
CCTGGCTAAC |
ACGGTGAAAC |
CCCATCTCTA |
CTAAAAATAC |
AAAAAATTAG |
|
| 17281 |
CTGGGCGTGG |
TGGCGGGCGC |
CTGTAGTCCT |
AGCTACTGGG |
GAGGCTGAGG |
CAGGAGAATG |
GCGTGAACCT |
GGGAGGCGGA |
|
| 17361 |
GCTTGTAGTG |
AGCTGAGATT |
GTGCCACCGC |
ACTCCAGCCT |
GGGCGACAGA |
GCAAGACTCG |
ATCTCAAAAA |
AAAAAAAAAA |
|
| 17441 |
AAAAAAAAAG |
GTGTTTGTGG |
TAGAAAGTGT |
TCTCACGGCT |
GCTGACTCAG |
AACCATGAGC |
CTGTGTGTAA |
GTCCTGGCCT |
|
| 17521 |
TCTCTTCAAA |
GGTGATGGCC |
CGCTCCCTCT |
CCCCACCCCC |
GGAGCTGGAA |
GAAAGGGATG |
TGGCCGCATA |
CTCGGCCTCC |
|
| 17601 |
TTGGAGGATG |
TGAAGACAGC |
CGTCCTGGGG |
CTTCTGGTCA |
TCCTTCAGGT |
GGGTGTTCTG |
CACGAGGCCT |
CTGCTCCCGG |
|
| 17681 |
GGCGCGCATG |
GCTAGCGTCC |
ACCAGCTGCA |
TCTGCGTTGT |
GTTGGAGTCT |
GTTCCCCAGC |
GGGACCCACA |
CCCTCCCTGG |
|
| 17761 |
ATTTGCTGAG |
GGTGCGGTGG |
TCTCAGCAGG |
CAGCAGAACC |
TTCCTCCTGC |
TCTTGTGGAG |
GGATGGATGC |
AAGAGGCCCC |
|
| 17841 |
GTTGTACGCC |
CTGACCAGAG |
CTTGTCTCTG |
TGCTCCTGAG |
TCAGGGCCGG |
AACCATGTAC |
CATCCTCAGC |
GTGGCGCTTG |
|
| 17921 |
CCCTCGTCAC |
CCAGCACAGC |
ACCTGGGAAG |
TAAGGGTGGC |
CCTCCATTCC |
TGCCCTGCAG |
TCCGTTTAAT |
ATTTGCAGCT |
|
| 18001 |
GTTTTGTTGA |
GATTTAATTT |
ACATATCATG |
CAATTTACCC |
ATTCACAGTG |
AACAGTTCAG |
TGGTTTTCAG |
TAAATTCACA |
|
| 18081 |
GAGCTCTGCA |
GCCAACCCCA |
CAGTCAGCTT |
GAGAACCTCC |
TGAGCATACC |
AGTAGCACAC |
GCTCCCATCC |
CCCGTTGCTC |
|
| 18161 |
CCGTACCCCC |
GGGTACCATC |
AAGCTGCTTC |
CTGTCTCTGT |
GGATTTACCT |
ACTCTCAACA |
TTTCATGGAA |
GTGGAATCAC |
|
| 18241 |
ACAAAATTCA |
TCCATAAGAT |
GTTGGATGGT |
AGAACAGTTT |
CCTGTCTGCT |
GACTGGATTG |
TTCCACCCAG |
CGCCATGTGT |
|
| 18321 |
CCAGGCCCGT |
CCAGGCTGTG |
GCAGCTGTTG |
GTGCTCCCCT |
CCTTTTCATG |
GCTGAGTAGT |
ATTCCATCAT |
CTGGAAGGAG |
|
| 18401 |
CACATTTTGT |
CTGTCCGTTC |
CTCCATTGGT |
GGACATTTGG |
CCTGTGTCCG |
CCTTGCAGCT |
GCGGTGAGTG |
GTGCTGCTGT |
|
| 18481 |
GAACCTTCTC |
CTACGAGGGC |
TCCGCCGGGC |
CTGCATTTTC |
ACTTTTGGGT |
CTGCACCTAG |
GAGTGAATTG |
TTGGGCCCTA |
|
| 18561 |
GGTTTAGTCT |
GCATTTGGTG |
TTTCAAGGCG |
ATACCAGGCT |
GTTTTCCACT |
GGTGCTGTGC |
CATTTTCCAT |
CCACTCGAGC |
|
| 18641 |
AGCATGTAAG |
GGTTCTGATT |
TATCTTTTTT |
TTTTTTTTTT |
TTTTTTTTGA |
TACAGTCTCA |
CTCTGTCGCC |
CAGGCTGGAG |
|
| 18721 |
TGGAGTGCAG |
TGGCGCGATC |
TTGGCTCACT |
GCAACCTTCG |
CCTCTTGGGT |
TCAGGCGATT |
CTCCTACCTC |
AGCCTCCTGA |
|
| 18801 |
GCATCTCGTA |
TTACAGGCAC |
CTGCCAACAT |
ACTCGGCTAA |
TTTTTTGTAT |
TATTAGTAGA |
AACTGGGTTT |
CACCATGTTG |
|
| 18881 |
GCCAGGCTGG |
TCTTGAACTC |
CTGACCTCAG |
GTGATCCTCC |
CGCCTTGGCC |
TCCCAAAGTG |
CTGGGATTAC |
AGGTGTGAGC |
|
| 18961 |
CACCACGCCC |
GGCCTGCCTC |
TACTTTTCAA |
AGCCTCACAG |
CATCACTTAC |
GTGTGACTGT |
CAGTGTCAGT |
ATCGTGTAAA |
|
| 19041 |
ATATAATGTA |
TGAATCAGTT |
TGCTCAAAAG |
CTCATCCTTA |
AGATGTTGGA |
TGGTAGAACA |
ATTTCCTGTC |
ATGTTTATAT |
|
| 19121 |
GTCATGGGTT |
TTTATTTCTT |
GCCATGGAAG |
TTGAAAGTGG |
TGATGATTTT |
TTTTTTTAAT |
TAATTTTTTG |
AGACAAGATC |
|
| 19201 |
TCACTCTGTC |
GCCCAGGCTG |
GGGTGCAGTG |
CTGTGACCAT |
AGCTCAGTGC |
AGCCTTGAAC |
TCCTGTGACC |
AAGTGATCGT |
|
| 19281 |
CCTGCCTCGG |
AGGCCTCCCA |
AGTAGCTGGG |
ACCATAGGCA |
CACGTCACCA |
CACCTGGCTA |
ATTTTTTCAT |
TTTTTGTAGA |
|
| 19361 |
GATGGGGTCT |
TTATATGTTG |
CCCAGCCTGG |
CATCAACCTC |
CTGGCCTCAA |
GCAGTTCTCC |
CACCATAGCC |
TCCCAAAGTG |
|
| 19441 |
CTGGGATTAC |
AGGCATGAGC |
CACCACACCT |
GGCCGTGGTG |
TTTGATTAAA |
AACCAGGCAT |
CAGCCGGGTG |
TGGTGGCTCA |
|
| 19521 |
TGCCCGTAAT |
CCCAGCACTT |
TGGGAGGCTG |
AGGTGGGTGG |
ATCACCTGAG |
GTTGGGAGTT |
CAAGACCAGC |
CTGACCAACA |
|
| 19601 |
TGGAGAAACC |
CCGTCTCTAC |
TAAAAATACA |
AAATTAGCCG |
GGCGTGGTGG |
CGCATGCCTG |
TAGTCCCAGC |
TACTCGGGAG |
|
| 19681 |
GCTGAGGCAG |
GAGAATCACT |
TGAACCCATG |
AGGCAGAGGG |
TACAGTAAGC |
CCAGATCACG |
CCATTGCACT |
CCAGCCTAGG |
|
| 19761 |
CAACAAGAAT |
GAAACAACGT |
CTCAAAAACA |
AAACAAAGCA |
AAAACAGGCA |
TCACCTCCTT |
GGTGTCTCAT |
CCACATGAGC |
|
| 19841 |
ACCATGCTCT |
TTACTGACTG |
GTTGGGAAGG |
GGTGTGCTGG |
GCTGTGGGGG |
CCTATGGCCT |
GGGAGAACTG |
AGAACCTTTC |
|
| 19921 |
TGCTTCTGCA |
GAGGGAAGGA |
AAGAGGTTCT |
GTTGCCCTTA |
CTTGGAACTC |
CAGCCCTGGA |
GGCCTGAGGG |
TCTGGGCTGC |
|
| 20001 |
AGAACTGAGA |
TATTTCCTAG |
TTGAGGCAGA |
GTCCTGGTTC |
TGGCTGCTTT |
CATTTCTTTA |
TTTTTTTGAG |
ATAGAGTCTC |
|
| 20081 |
ACCACTATGT |
CACCCAGGCT |
GGAGTGCAGC |
GGCACGATCT |
CACCTCACTG |
CAACCTCCGC |
CTCCCAGGTT |
CAAGCAATTC |
|
| 20161 |
TCTTGCCTCA |
GCCTCCTGAG |
TAGCTGAGAT |
GACAGGTGCG |
CACCACCACA |
CCTGGCTAAT |
TTTTGTATTT |
TTAGTAGTGA |
|
| 20241 |
CATGGTTTCA |
CCATGTTGGC |
CAGGCTGGTC |
TCAATCTCCT |
GACCTCAAGT |
GATCCACCCA |
CCCCAGACCC |
CCAAAGTGTT |
|
| 20321 |
GGGATTACAG |
GCGTGAGCCA |
TCGTGCCTGG |
CCTGTTTTCA |
TTTCTTTTGT |
TATAATTGAA |
AAGTAACACA |
GTTGACTCTT |
|
| 20401 |
GAACAGTATG |
GGGCTGGGAG |
TGCCAGCCCC |
TGTGCAGGTG |
AAAATCCCCA |
TCTAACTTTT |
AACTCCCCAG |
AAACTTTACC |
|
| 20481 |
AACAGCCCTC |
TGTTGACTAG |
AAGCCTTGCT |
GATAGCAGAC |
AGTCTATTAA |
TGTACAGCTC |
GTGTGTTTTA |
TGTATTCTGT |
|
| 20561 |
GTTTTTACAG |
TGAAGTAAGC |
TAGAGAAAAG |
CAAATGCTGT |
TAAGATGCTA |
GGCATGGTGA |
CTCACGCCTG |
TAATCCTGGC |
|
| 20641 |
AGTTTGGGAG |
GCCGAGGCGG |
GCAGATCATG |
AGGCCAGGAG |
TTCGAGACCA |
GCCTGACCAA |
CATGGTGAAA |
CCCCGTCTCT |
|
| 20721 |
ACTAAAAATA |
CAAAAATTAG |
CTGGATGCGG |
TGGTGCGCAC |
CTGTAATCCC |
AGCTACTCGG |
GAGGCTGAGG |
TAGGAGAATC |
|
| 20801 |
ACTTGAACCT |
GGGAGGTGGA |
GGTTGCAGTG |
ACCTGAGATC |
GTGCCATAGC |
ACTCCAGCCT |
GGGCGACAGA |
GAAAGACTCC |
|
| 20881 |
GTCTCAAAAA |
AAAAAAAAAA |
AAAAAATCAT |
AAGGAAGCGA |
AAATACATTT |
CCTGTTCCTT |
AAGTGGAAGT |
GGCTCATCAC |
|
| 20961 |
CAAGGTCTTC |
ATTGTTGTCA |
TCCTCATGTT |
GAGGGGACTG |
AGGAGGAAGG |
AGAGGAGACA |
CATGGTCTTG |
CTCTCTCGGG |
|
| 21041 |
TGGGAGAGGC |
GGAAGAAAAT |
TGGCATGTAA |
GTGACCCATG |
AAGGCCAGCC |
TCGTGCTGTT |
CGAGGGTCAG |
AGAGTTTGCA |
|
| 21121 |
CAATGGACAC |
GGTGACAAGT |
TTGATTCCCC |
TTTTCCTGCC |
TGCCTAGTGG |
GCCCGGCAGG |
GCGGCAGCTG |
CTGTTGGTTC |
|
| 21201 |
CATGTGGCCT |
TCCCAGAATG |
GGGGGTGCCA |
GGCACTGTGT |
GAACCCCCAC |
CTCCACCTCT |
TTTTTGTCCG |
AGGAAGGGAT |
|
| 21281 |
GTTGCTTTTA |
TGTCATAATA |
TTTTGAGATG |
AGGAGAAACT |
GTTAATCATT |
TAATCATCTT |
TTTTTTTGAG |
ATGGAGTCTC |
|
| 21361 |
GCTCTGTCGC |
CCCAGCTGGA |
GTGCAGTGGC |
GCAATCTTGG |
TTCACTGCAA |
CCTCCGCCTC |
CTGGGTTCAA |
GCGATTCTCC |
|
| 21441 |
TGCCTCAGTC |
TCCTGAGTAG |
CTGGGATTTA |
CAGGCATGCA |
CCACCACACC |
TGGCTAATTT |
TTTTTTTTTT |
TTGAGACAGT |
|
| 21521 |
CTTGCTCTGT |
CGCCCAGGCT |
GGAGTGCAGT |
GGCACGATCT |
CGGCTCACTG |
CAAGCTCTGC |
CTCCTGGGTT |
CACGCCATTC |
|
| 21601 |
TCCTGCCTCA |
GCCTCCCAAG |
TAGCTGGGAC |
TACAGGTGCC |
CACCACCACG |
CCCGGCTAAT |
TTTTTTGTGT |
TTTTAGTAGA |
|
| 21681 |
GACAGGGTTT |
CACCATGTTA |
GCCAGGATGG |
TCTTGATCTC |
CTGACCTCAT |
GATCCACCCG |
CCTCGGCTTC |
CCAAAGTGCT |
|
| 21761 |
GGGATTACAG |
GCGTGAGCCA |
CTGTGCCCGG |
CCTAATTTTG |
TATTTTTAGT |
AGAGATGGGC |
TTTCTCCATG |
TAGGTCAGGC |
|
| 21841 |
TGGTCTTGAA |
CTCCTAACTT |
CGTGATCCAC |
CCACTTCAGC |
CTCCCAAAGT |
GCTGGGATTA |
CAGGCGTGAG |
CCACCACACC |
|
| 21921 |
TGGCCTCAGT |
CATTTCTTTC |
AATGATTTTT |
TAATCATTTA |
AAGGTGTTAA |
TCATTTCTTT |
AAAAGAATAA |
CAGTGTAACC |
|
| 22001 |
ACTTACCTCC |
AGAGTGCTGC |
AAAGGGTCCC |
TCAGGCCAGA |
TTTCCCCTGG |
CTCCTGCTGG |
CCTCGGCCCC |
AGGGTTGCTG |
|
| 22081 |
GAGGCAACAG |
ATGCTCTTCA |
CACCTTGCCA |
CACGTGTCTG |
GGAGGTGCCC |
TTGACCTTTT |
GGGAGGGGCT |
GCCTACACCT |
|
| 22161 |
GGGATCGCCC |
TGCAGCACAC |
ACTCCCCGCC |
CCATTCTGCC |
CTGTCTGCCA |
CGCAGCTGGA |
GCTTCTCCAT |
TGAATGGACT |
|
| 22241 |
CTTCCTCACC |
TGTTGATGAC |
TGCCCTGATG |
ATGAGATGGG |
CACGAGGTTG |
GGTTTTACTT |
TTTGCTGCTG |
TGGAGAGAGA |
|
| 22321 |
GTCCTGGTGG |
TCCTGGGTTT |
GAAGGTCGTG |
TGTTTTGAAG |
CACGCACTCT |
AGAGCAGCCG |
CCCCGGCCCC |
TGCTCCGGGA |
|
| 22401 |
CAAGGGTGCT |
GTCTTAGGAC |
TGCGTTTTCA |
CCTCCTGCGC |
CGTGGTGAGC |
TGCGTCCTCT |
CTCTGCAGAC |
CAAGCTGTAC |
|
| 22481 |
ACCCTGCCTG |
CAAGCCACGC |
CACGCGTGTG |
TATGAGATGC |
TGGTCAGCCA |
CATTCAGCTC |
CACTACAAGC |
ACAGCTACAC |
|
| 22561 |
CCTGCCAATC |
GCGAGCAGCA |
TCCGGCTGCA |
GGTATGGTGG |
CTGGGGTTGC |
GCAGCCAGTT |
CCTGGGGGCC |
CAGCCAGGTA |
|
| 22641 |
TCCCCGTCTC |
GGCAGGTGTG |
GTTCCTGGAA |
GCTGCAGAGA |
CGGCCCCAGG |
ATGGGGCCTC |
AGCTGACCGT |
CCCTCCTCTG |
|
| 22721 |
CACCCACTGT |
GGCCGCAGCC |
TCCCCAGTCC |
TGGTGTCCTT |
CCCTCTGCCT |
GCAGTCCACA |
CATCTGTGGC |
TTGTCGCTCT |
|
| 22801 |
AAGCCGCACG |
GTGACATGGG |
TTGGGGCAGA |
GAAAAGGACG |
CACGGCGACT |
TCCGGGGCAG |
TGCATGGCCC |
TGACGCTCCT |
|
| 22881 |
GGTGCTGCAG |
AATCTGTGAA |
GGACCTGCAG |
CAGAGGGCTG |
GGCAGGTGGG |
CGGCACAGGG |
CAGAGCTGAG |
AGGGCAGAGC |
|
| 22961 |
TGAGACGGCA |
GGGCAGGGCT |
GGAGAGGGCA |
GAGCTGAGAG |
GGCAGGGCAG |
GGATGGGCAG |
AACAGGGCTG |
GAGGAGTTTC |
|
| 23041 |
GCTGAGTTTG |
CGCTATAGAT |
GTTGGCACCA |
GGCTGAGCAG |
AGGTGACTGG |
GATGGGAGCC |
CTCCCTCCTA |
GAGCAGGTGC |
|
| 23121 |
TCTCTGGGGC |
CACCCCTGTG |
GCCTCAGAGT |
CCTGTTCAGC |
CTGTCGATGG |
AAGAAGTGGC |
AGGGCTGGGA |
GCTGAGCTCC |
|
| 23201 |
GCTTTCTGGC |
AGTTGGGGGC |
GTGTGGTGCT |
GCCAGAGGAG |
CGAGGCGCCC |
ATCCCTTCCA |
TCCCAGGCGG |
GCCCAGCTGT |
|
| 23281 |
GGTGGTGGGG |
ACACCAGGCT |
CTGTGAGCTC |
CGAGGCAAGG |
GAGGGAGGAG |
GCTGTGGGTG |
CTGGGCCTCC |
GGTGTCACCA |
|
| 23361 |
GGACAGAGCC |
TGTGTCTGTG |
TTGGGATGTG |
GGTGTGTGCA |
CATCAGCAGG |
TGGCCTTTTC |
TGAGTGCCTG |
TGGTGCTGGA |
|
| 23441 |
CGTGGGTCTG |
AGCAGGTGGG |
ACGCCGCCTG |
TCCTGGGCCT |
GCACGAGCTT |
GGCTCTGGCT |
TTCACCATCC |
TCTTCCTGAC |
|
| 23521 |
AGGCCTTTGA |
CTTCCTGTTG |
CTGCTGCGGG |
CCGACTCACT |
GCACCGCCTG |
GGCCTGCCCA |
ACAAGGATGG |
AGTCGTGCGG |
|
| 23601 |
TTCAGCCCCT |
ACTGCGTCTG |
CGACTACATG |
TACGCGGGAC |
CTCGCCCACG |
GCCCATGAGG |
CTCAGGGCGT |
CAGAGGCGCT |
|
| 23681 |
GGGGCTGTGG |
TGGCGCTGTT |
TGCATGTCTG |
AGGGATGTCC |
CAGGGTTGGG |
AAGAGCCAAG |
TCTGTTCCGT |
TCCTGCTGCG |
|
| 23761 |
GGGACTTGGC |
CTCAGCTGCT |
TCTCTTGCTT |
CTGCAGGGAG |
CCAGAGAGAG |
GCTCTGAGAA |
GAAGACCAGC |
GGCCCCCTTT |
|
| 23841 |
CTCCTCCCAC |
AGGGCCTCCT |
GGCCCGGCGC |
CTGCAGGCCC |
CGCCGTGCGG |
CTGGGGTCCG |
TGCCCTACTC |
CCTGCTCTTC |
|
| 23921 |
CGCGTCCTGC |
TGCAGTGCTT |
GAAGCAGGTG |
AGTGGGGCCG |
GGCAGGGACC |
ATCCGTCCCA |
CGTTGGGCCA |
GGAGGACAGG |
|
| 24001 |
GAGCTGCCAC |
CTGCCTGCTG |
GGCCTCCCTC |
CCTGTCTGGC |
CTGTGGAGGG |
CAGCCCTCCC |
TCAGAGCTGA |
GCCTTCCCCC |
|
| 24081 |
TTCCCCGAGC |
AGCTGCAGGG |
ACAGAGGCCT |
GCGCTGGGCA |
GGCTCCCCCG |
GCTGAGAACA |
GGGCTCCATA |
GCCCTTGACG |
|
| 24161 |
CTGTGCAGCC |
ACAAAGCAGA |
GCCTCAGATG |
CTAGCTTCCG |
CCTCTGTCTC |
TAGGGTCCAG |
AAGGCCCTGT |
CCTGACGCCT |
|
| 24241 |
CCTCTCCTCG |
CAGGAGTCTG |
ACTGGAAGGT |
GCTGAAGCTG |
GTTCTGGGCA |
GGCTGCCTGA |
GTCCCTGCGC |
TATAAAGTGC |
|
| 24321 |
TCATCTTTAC |
TTCCCCTTGC |
AGTGTGGACC |
AGCTGTGCTC |
TGCTCTCTGC |
TCCATGGTAC |
CATGGCCGGC |
CTGGGGTTGG |
|
| 24401 |
GGTGGGGGAC |
CCAGTAGGGT |
TTTTCCCCAA |
AAGACTGCGA |
GCCTCTGGGC |
AGAGCGAGTG |
AGACCCTTCG |
GGCTCGGGCT |
|
| 24481 |
CCATTTCCCT |
CAAACTCAGC |
TGCACTCTGG |
AGCGCAGATT |
GTGCCTTGGG |
CAGGGTGGAG |
GGACCCCTGC |
CCCAGCTCGC |
|
| 24561 |
AGCTTTTGGG |
ACTGACGTCA |
GAGGTCCCCA |
GCCAAGGGCA |
TGTCACTGAA |
TGTGGATGTC |
TCCCATCTGT |
GCTTTTCCTA |
|
| 24641 |
AGTGGGGCTC |
CCGTGCCGTT |
CACCTCACAT |
TCCTGGTGTG |
TTACTTGGCA |
GGCACTCCCA |
CCACTCCGAA |
AGGGAGGCCC |
|
| 24721 |
TTCCTGGGAG |
GGAGGCAAGA |
AGGCTCCCCA |
GCCCCTTTGC |
CCCCTTTCCT |
GGGCCTGCGT |
TCCCAGGGCC |
TCCCCAGCCC |
|
| 24801 |
CTCTGGCTAC |
CCCGTGACCT |
GGCCGCTGGG |
GAGAGGTTTC |
ATGCCTGGAT |
TTGGTCATCA |
GCTTTCAGGC |
CCAAAGACAC |
|
| 24881 |
TGGAGCGGCT |
CCGAGGCGCC |
CCAGAAGGCT |
TCTCCAGAAC |
TGACTTGCAC |
CTGGCCGTGG |
TTCCAGTGCT |
GACAGCATTA |
|
| 24961 |
ATCTCTTACC |
ATAACTACCT |
GGACAAAACC |
AAACAGGTAG |
GAGGTCAGAG |
CAGGACAGGC |
GAGCTTGATG |
GGGCCTGGGA |
|
| 25041 |
TTCGAGGGCC |
TGGCCCAGGT |
AGGCCCCACA |
TTTTTCTCAT |
AAACGAGTTT |
CTGCCAGGCC |
AGGGATGAGT |
GAGTTGGCTC |
|
| 25121 |
TGCTTCCCTG |
GGTGGCTGCC |
AGATGCCCAG |
AGTGGGGACA |
TCCGATTCCC |
TGGTGCTTCT |
AGCTCTCTTT |
GGGGCCTGGG |
|
| 25201 |
AGCCATCCAG |
TGTTCCCTGT |
CCACCCCGGA |
CAGCATCTCT |
GCTCTCTGTA |
GAGCGTTGCC |
TGGCTTGTTC |
CTGCTGTCCC |
|
| 25281 |
AAGGGGGAGG |
TGGCCATGCC |
GGTTGGTGGA |
GCTGGGCTGG |
TTCTGAGGCG |
CAGGGTGGGC |
AGGCCAGAGA |
GTCTGGCTTC |
|
| 25361 |
TGCCTCCCTC |
CACGCCCCAT |
CAGGTGCCGG |
AAACTGTCCC |
TTCACCTGCG |
ATCTGCCTCG |
CCCCCGTCCC |
AGTCGCATTC |
|
| 25441 |
TTCCACACCT |
CTCTTTGACA |
TGGCCCTCCG |
GGACGAGGAG |
CTGGTGTCCT |
AGAGATTCTG |
GCCTCCGCTC |
AGGGCCATGC |
|
| 25521 |
CCGCCAGGAG |
ATGCTGACTC |
TGAGGCTTGG |
CCCATCTGTG |
CCCCGGGCCT |
CAGCTTCTGA |
TGGTGGCCCT |
GTAGGGAGCT |
|
| 25601 |
GTTGTTGGGT |
TCCCATCCCT |
CAGGCTCAGC |
CCCACCCTGT |
TGGGCCCCTT |
CAGCCCCTCT |
GAGAGGCTCA |
CTGGGTCCTC |
|
| 25681 |
ATGGGTCTTG |
CCTCAAAGCA |
TAGCCAGCCT |
TGCTGGGCTG |
CAGGTTCTGA |
GGCCTTACTG |
GCCCACAGTG |
TATCCGAGGG |
|
| 25761 |
GTGAGGCCGG |
CTTTGGGAAA |
TGGAAGCTGT |
TCCCGGGACA |
CTGCCTGGCA |
GGCCATCTGG |
CCCCGGGCTC |
TGCCTGAGCT |
|
| 25841 |
CCGCTCATCT |
TCTGCTGTCC |
TCATGGAAGA |
CACTGCCCAG |
GGTTGGTGTG |
GGATCTGGTG |
GCTTGGCCAC |
TTCAGGCAGC |
|
| 25921 |
ACTGCCCCTT |
GCAACAGAGC |
CAGCCTGTGA |
AGGGCCCAGA |
ACCAGGGGAT |
GAGAGCCCAG |
CATGTCTGGG |
TTCTGTTGGC |
|
| 26001 |
CTGTGGGATC |
GTGTCGGAAT |
GCAACTGACC |
GGAGCAGTCT |
GCTGTGCAGA |
GTCTGCTCGG |
GTAGCTCAGC |
ACTGCTGGCT |
|
| 26081 |
CTGCCCCACA |
GGCATTCAGG |
GACTTGCTAA |
GCCTCGGCTG |
TTCTCCCGGT |
GGAGCACTCG |
AGGTTGGCGA |
GGGGTAGGCG |
|
| 26161 |
AGGCTGCCTC |
TGCTGCAAGC |
GGGTGGGGCC |
TGAGGTGTCC |
TGTCTCCTGC |
AGCGCGAGAT |
GGTCTACTGC |
CTGGAGCAGG |
|
| 26241 |
GCCTCATCCA |
CCGCTGTGCC |
AGCCAGTGCG |
TCGTGGCCTT |
GTCCATCTGC |
AGCGTGGAGA |
TGCCTGACAT |
CATCATCAAG |
|
| 26321 |
GCGCTGCCTG |
TTCTGGTGGT |
GAAGCTCACG |
CACATCTCAG |
CCACAGCCAG |
CATGGCCGTC |
CCACTGCTGG |
AGTTCCTGTC |
|
| 26401 |
CAGTGAGTCC |
CCGCCCTGCC |
TGCGCATGCA |
CCCGAGAGGT |
TCGGGCTGTG |
TAACCTGTGC |
GGGCTTCTCT |
GGTGCCCTCT |
|
| 26481 |
CTCAGGACTC |
CTTGGGGAAC |
CTGGGTGTCT |
CGCCTTCTGC |
TGCCTCAGGG |
CCTGGGCGTC |
TCTGCCCGGC |
TGCCATGAGT |
|
| 26561 |
GCTCTCCTTC |
CTGGCTTTGA |
GGGGCGGCTC |
CTCTCACCCC |
TCTAGTGTCC |
ATGTGAACGC |
TCCTCCTTGA |
AGAAGCCTCT |
|
| 26641 |
TCCCCCCCGA |
GCAGTGGCCC |
TCCCCTGGTT |
TTGGGCCTCC |
TCTCTGTCCA |
ACAGAGCACA |
CGCCGCTTCA |
GGGGGGCTTT |
|
| 26721 |
GTTCGCTTCC |
CCCAGACTGT |
GACTTCAGGA |
GCTCAGGTGC |
CTGTCCCTTC |
CCCTCACCGC |
CTGTGCGCAT |
CTGGGCAGGC |
|
| 26801 |
CCTCAATGTT |
GAGATGGCAG |
AAGGGCACTG |
CTGGGCCCGC |
ACTTGGTGTA |
GAGGCTGGAG |
AGAAGATCGT |
GTGTGCTTTG |
|
| 26881 |
TGGGCCACAT |
GCAGGTCCTG |
TCGGTCTTTC |
TGTTTTGTTG |
ATAACCCTTT |
AGAAGTGTAG |
AAGCCTGGCC |
AGGCGCGGTG |
|
| 26961 |
GCTCAGGCCT |
GTCATCCCAG |
CACTGTGGGA |
GGCCGAGGCG |
GGTGGATCAC |
CTGAGGTCAG |
GAGTTCGAGA |
CCAGCCTGGC |
|
| 27041 |
CAACCTGGCG |
AAACCCTGTC |
TCTACTAAGA |
ATACAAAAAT |
TAGCCGGGTG |
TGGTGGCGGG |
TGCCTGTAGT |
CCCAGCTACT |
|
| 27121 |
CAGGAGGCTA |
AGGCAGGAGG |
CAGGAGAATC |
TCATGAACCC |
AGGAGGTGGA |
GCTTCTAGTG |
AGCTGAGATC |
ACGCCACCGC |
|
| 27201 |
ACTCCAGCCT |
GGGCAACAGA |
GCGAGACACC |
GTCTCAAAAA |
AAAAAAAGAG |
AGAAGTGAGG |
CCGGGCACGG |
TGGCTCACGC |
|
| 27281 |
CTGTAATCCC |
AGCACTTTCG |
GAGGCCGAGG |
CAGGCGGATC |
ATGAGGTCAG |
GAGATCGAGA |
CCATCTGGCG |
AACACGGTGA |
|
| 27361 |
AACCCCGTCT |
CTAATAAAAA |
TACAAAAAAA |
CTAGCCAGGC |
GTGGTGGCGG |
GCGCCTGTAG |
TCCCAGCTAC |
TTGGGAGGCT |
|
| 27441 |
GAGGCAGGAG |
AATGGCGTGA |
ACCCAGGGGG |
TGGAGCTTGC |
AGTGAGCCGG |
GATCGCGCCA |
CTGCACTCCA |
GCCTGGGCGA |
|
| 27521 |
CAGAGCCAGA |
CTCATCTCAA |
AAAAAAAAAA |
AAAAAAAAAA |
AAAGAGGTGC |
GGAAGCCTTT |
CCTCACGGAT |
CACACAAATG |
|
| 27601 |
GTAGGCGACA |
GCTCGAATTG |
GCCCAGAAGC |
TGTGGTTGGC |
TGGCCATGGG |
ACCGAGAGTT |
GAGGCCAGGG |
TCGGGAAAGC |
|
| 27681 |
CACGTCCGTG |
TGGCCGTGGC |
CTTCTCTCCT |
CTGCAGCACC |
CCATCGCTGC |
CGTGGGCAGA |
GCAGCCGTGT |
TGGCCTTCAG |
|
| 27761 |
AGGCGCTGCA |
CGGGACCCCG |
GCTCCCCTGA |
CCACCCTCTC |
CATTACCGCA |
GCTCTGGCCA |
GGCTGCCGCA |
CCTCTACAGG |
|
| 27841 |
AACTTTGCCG |
CGGAGCAGTA |
TGCCAGTGTG |
TTCGCCATCT |
CCCTGCCGTA |
CACCAACCCC |
TCCAAGTGAG |
TGGTCGCCCC |
|
| 27921 |
AGGCCCTGTG |
CCTCCCAGCC |
GTGGCCCCCG |
CTAGGCCTTG |
CGGCAGAAAG |
CCCCGGCAGC |
CTTTGTCCCC |
AAGGCCTGAG |
|
| 28001 |
CGCCTCGGTT |
TTTTGCACTT |
CATGCCCTGG |
GGATGTTTCC |
CTGCTGCCAG |
GATGGAGTGC |
CAGCCCCCTT |
CTCATCTCAG |
|
| 28081 |
GTTTAATCAG |
TACATCGTGT |
GTCTGGCCCA |
TCACGTCATA |
GCCATGTGGT |
TCATCAGGTG |
CCGCCTGCCC |
TTCCGGAAGG |
|
| 28161 |
ATTTTGTCCC |
TTTCATCACT |
AAGGTGGGCT |
CAGGGCCGGT |
GAAGGCTGTG |
TCTCTCGGTA |
GGCCAGGGCT |
TGCTTTGCCC |
|
| 28241 |
TTGGCTGTCC |
ATGGTCGGGC |
AGAGTGACAG |
GCAGGTGGAG |
GGCAGTGGGA |
GGGTGTTTGG |
GGCTGTGCCT |
GTGGCGCTGG |
|
| 28321 |
GGGCTCTGCT |
GGGCAGCCTG |
CAGGGCTTTG |
ATGCGCGGCA |
GGCATTGAGG |
GGTGGGAGCT |
GGGTGCCGCC |
GCCTTGCCCC |
|
| 28401 |
TAGCCTGCAG |
CTTGTCCCTG |
GCCAGGGGGC |
ACCCGGCAGG |
CCTGGTGAGG |
GCCTCCAGCC |
CCCATTGCCA |
CCCCTCACTG |
|
| 28481 |
TCTGGGTGTG |
CTCACTCTGC |
CAGGGCCTGC |
GGTCCAATGT |
CCTCTTGTCT |
TTTGATGACA |
CCCCCGAGAA |
GGACAGCTTC |
|
| 28561 |
AGGGCCCGGA |
GTACTAGTCT |
CAACGAGAGA |
CCCAAGAGGT |
ACGGCCTGCG |
GGGGTGTGCC |
TGGAGTCGGT |
GTGGGGTGGG |
|
| 28641 |
GAAGGACATG |
GGGCTGTGGC |
CTGCCTGACG |
GTGCCTCCAA |
GTCAGTGAGT |
GGAAATGGGT |
CCTGTGTGCC |
CTGGAGTATG |
|
| 28721 |
TGAGGCAGGG |
CAGGACCTGC |
AAGGGCCGCT |
AACACCCCTC |
AGCCCCTCAG |
CAGGTTGGCC |
GTGGTGGCCT |
GGGTCCGGGC |
|
| 28801 |
TGCGTGTGCC |
ACGGGCACCT |
ACTTGTGGAA |
TTGGGGGTTG |
GGGTGCAAGC |
TTTAGGCGCC |
TGAGCCCCTC |
GAAGGAGCCG |
|
| 28881 |
GCCTTGTCTG |
GGGCTGCCCC |
CTCCTCTGCA |
GCCCCCAGCC |
TGCTGCTAGC |
CGGGGACTCT |
GCTTCATCAC |
CGCCGCCTTG |
|
| 28961 |
CCGGACCGCA |
AAGAGCTGAG |
CCAGCCTCTG |
TGTTCTTGTT |
TGCATTTCAT |
TTGAACGGCT |
TTCTCCTCCT |
GTCCCCCACC |
|
| 29041 |
TTCCTGCCCG |
AGCTATTTTG |
GCTTTCCCTA |
GATGGGAATA |
CGGCATTTTC |
CAGCGTGACC |
TCAACTCGGA |
AGCTGTTGTC |
|
| 29121 |
TCCAGCCCCT |
GGGGGCCGGG |
GGCCAAGCTC |
GGCCATTACG |
GCCAGAGACT |
ACTTTCTGGG |
GTCTTGGTCT |
CTTTTCCTAG |
|
| 29201 |
TGACCTTCAG |
GGCCTGGCCA |
CTGAGGCCTC |
AGTGCCGCCT |
CGGTCAGAGC |
TGGGCGGTGC |
CTGCCTTCCG |
CGGGTGGGTG |
|
| 29281 |
GGATTGCCTG |
GCCAGCACAG |
CCTGGAATCT |
GCCGTGGGGG |
TGACCCACAC |
ACGTTTAATT |
TGCACTGACG |
TTGTTTGTTT |
|
| 29361 |
TGGTGTCATG |
CGTGAAGCCT |
TACTTGTTCT |
CAGTCATGTT |
TACCAGACGT |
ATTATCATGC |
ATTTTTGTTT |
TCTGTCTCTT |
|
| 29441 |
CCCCGCTAAC |
TGCCCTTTGG |
CATGGCTCTT |
TTTGCTCATC |
TCACCCGCGG |
GATCTCTCCA |
TCCTGACCCT |
GTGGCCTGGG |
|
| 29521 |
ACCTTTCCTC |
CTCACCCCTC |
CACTGGCTTG |
TTCTCCCCTT |
CCCGGGAGCT |
GGGCTCTCTG |
GGGCGTTGGG |
GCTCCTTCCT |
|
| 29601 |
CACCCGATAG |
TCTGAGGATA |
GCCAGACCCC |
CCAAACAAGG |
CTTGAATAAC |
TCTCCACCCG |
TGAAAGAATT |
CAAGGAGAGC |
|
| 29681 |
TCTGCAGCCG |
AGGCCTTCCG |
GTGCCGCAGC |
ATCAGTGTGT |
CTGAACATGT |
GGTCCGCAGG |
TAGCGGGACT |
GTCGGGTGGG |
|
| 29761 |
GGGCACGGAC |
CCTGGAGCTT |
GGCCCCGTGA |
GCACCTGGGT |
GGCAGTGCAT |
GGGGCTGCTT |
GCATGACCTC |
ATCGTCTGCC |
|
| 29841 |
CGTGTCCTCC |
CTGGCCAGCC |
CAGGGGGAGC |
CGGTGACGAG |
GGGTGGAAAG |
GTTGCATTCT |
GTCCCCAGGC |
CCCGTATGAG |
|
| 29921 |
CACGGGCTGG |
TTGCACGCAT |
CCCCAGGCCC |
CCTCGGGGTG |
CCGCTCCGAG |
AGAGCCAGGC |
GTGCCGGGCA |
GCAGCCTCCC |
|
| 30001 |
CAGGCTGTCC |
CCAAGGGCCG |
CAGTGTGGGT |
TGGGGGAGAC |
ACCACTCCTG |
GTTTTGGCCT |
TTTCGTATTC |
TCTAGAATGG |
|
| 30081 |
ACGTTTTTCT |
TCGGGCTTTC |
TTCTCAACAA |
GGTTTATTTT |
TTGTTGTAGC |
TGAAAGGGAA |
CAAGGGGCAT |
TTGTGGAGGG |
|
| 30161 |
TGCTGGGGTG |
GGGCAGCCTG |
GGAGGGCCTG |
GGTGGGGGCT |
AGGATCCTGC |
AGGGCATGGG |
CATGGGCCTG |
GGCCCCAGGC |
|
| 30241 |
CATGGTCTTA |
GTTCTCCCCG |
CAGTGTCTGG |
GTGCAGGTGT |
GGGCTCTCGG |
GCTCTCGGCT |
GTCACCTGCC |
TGTGGGTCAT |
|
| 30321 |
CGCTGCTGGC |
ACTGGCAGAG |
GGGATACCTG |
TCTCCTCCTG |
GAAGCCCGTT |
GCAGGCCAAG |
GGGTCCCATG |
GCCCTCAGTC |
|
| 30401 |
CATCCACCTC |
CTCACCTCAG |
GCCGGCCTCT |
GCTGGGTGGG |
ACTTGGCCAG |
GGGTTGGGGT |
GGTAGAGGTG |
CTCGGTGAGG |
|
| 30481 |
CTTAAAGCCA |
TTTTCTAGCA |
CATTCTGTAT |
CATGAGCAAA |
ATATTGCCTA |
GGGGCTATGA |
AATTTGTATC |
AGAATGAACT |
|
| 30561 |
CCCATAAGCC |
TCTTCCCTGT |
CACTGGGTGT |
GGAGCTCAGG |
CAGCCGCTCG |
CCTGCCTGAG |
GGTGACGGTG |
GAAGGCCACA |
|
| 30641 |
TGGGGATCCC |
AGACCTCTGT |
GTGCTTGCCG |
GAGGCAGCCT |
GCGGGCAGAA |
TGCAATCTGG |
GCCTGTCTGT |
GTGGCCTCCG |
|
| 30721 |
CCTCTCTGCA |
TGACTACACC |
GTTTCGCCAG |
GAGGCCGTAA |
CCTAGTGCTC |
CCGTGGGCTT |
CGGTGAGGGG |
GATGTCGGTC |
|
| 30801 |
TCTAGCCTCC |
TGAGTCTGCT |
CCGACCAGTA |
GGCCTGGTCT |
TCCCCACCCA |
GCGTCTCCCC |
GTTCTCTGGG |
ACAATGTGGT |
|
| 30881 |
CCACGTGATT |
CTCAAGCTGA |
GGCTCGCTGG |
GCCGCCCACG |
CCCTGTTGGG |
GTCTTTCCGA |
GCGAGGTCCT |
CAGCCGTGCA |
|
| 30961 |
TGCGTTGAGC |
TTTGGCCCTT |
GGTGATAGGT |
GGCTCGGCCC |
GCCCTACCTG |
GCACCCTGAC |
CCTGGTCACG |
GCCTCTCCCT |
|
| 31041 |
CCAGCAGGAT |
ACAGACGTCC |
CTCACCAGTG |
CCAGCTTGGG |
GTCTGCAGAT |
GAGAACTCCG |
TGGCCCAGGC |
TGACGATAGC |
|
| 31121 |
CTGAAAAACC |
TCCACCTGGA |
GCTCACGGAA |
ACCTGTCTGG |
ACATGATGGC |
TCGATACGTC |
TTCTCCAACT |
TCACGGCTGT |
|
| 31201 |
CCCGAAGAGG |
TCCAGGCGGC |
ACTACAGGGC |
TGGGCGGGCC |
TGCGGGAGCT |
CCACGGGCAA |
GCTGGGTTTC |
ACGCTCCCTG |
|
| 31281 |
TCTTCTAGGT |
CTCCTGTGGG |
CGAGTTCCTC |
CTAGCGGGTG |
GCAGGACCAA |
AACCTGGCTG |
GTTGGGAACA |
AGCTTGTCAC |
|
| 31361 |
TGTGACGACA |
AGCGTGGGAA |
CCGGGACCCG |
GTCGTTACTA |
GGCCTGGACT |
CGGGGGAGCT |
GCAGTCCGGC |
CCGGAGTCGA |
|
| 31441 |
GGTGACTGCA |
CCTTCCTTTC |
CTCCGCGCCT |
GCCAGCCTCG |
ACACCGGCTG |
TCCCGAGCCC |
AGGCCCACGT |
GGCACCCTCG |
|
| 31521 |
TACCAGCCTG |
GGGACTAAGT |
CCACCCTGTG |
CGTGGGATTC |
TCTTCTCAGC |
TCCAGCCCCG |
GGGTGCATGT |
GAGACAGACC |
|
| 31601 |
AAGGAGGCGC |
CGGCCAAGCT |
GGAGTCCCAG |
GCTGGGCAGC |
AGGTGTCCCG |
TGGGGCCCGG |
GATCGGGTCC |
GTTCCATGTC |
|
| 31681 |
GGGTGAGCCT |
TGGCCCCAGC |
CACCTCCACA |
CAGGCACCGG |
GGCTCCCTCA |
GTTGCTGCTG |
GTCCCAGTGT |
TCAGGAAGGC |
|
| 31761 |
CCCGAGCCCA |
GGGGCCGGGG |
TGGCTGGCTT |
CAGGCCCGGC |
CCACGTCCTG |
ACTCTGGGGT |
GAGCCTTCCA |
CAGCTCACCC |
|
| 31841 |
CAGAGCCGTG |
GAGTGGTGGA |
GTGTGGCCCG |
CTTGCTGCAG |
AGGGGCCTGC |
TCTGGGTGCT |
GGTGTTTCCT |
GCGGGTTTTC |
|
| 31921 |
AGCTCGGCTC |
AGTCCTGGAG |
CCCTTCTCTG |
CTCCAGCGAG |
CCGTGGTCTG |
ACTGCAGGAC |
AGGTTCTGGG |
TCCCTCCCTG |
|
| 32001 |
TGGCCCTGGG |
TTCACTGAGG |
CCAGCACTGT |
GGTGGGCCGT |
GCCCCAAGGG |
CAGAGCTGCC |
ACCGTCTCTG |
GCTGCCTGTG |
|
| 32081 |
GCACTAGCTT |
GCCAGGCTCG |
GGGGGAGCAT |
TCAGCTTGAG |
GCTGGTGGTT |
TTGCATCAGG |
TAAGTGGTGG |
TCACCAGTCC |
|
| 32161 |
TCTGCCCTCT |
TCTTCAGGGG |
GCCATGGTCT |
TCGAGTTGGC |
GCCCTGGACG |
TGCCGGCCTC |
CCAGTTCCTG |
GGCAGTGCCA |
|
| 32241 |
CTTCTCCAGG |
ACCACGGACT |
GCACCAGCCG |
CGAAACCTGA |
GAAGGCCTCA |
GCTGGCACCC |
GGGTTCCTGT |
GCAGGAGAAG |
|
| 32321 |
ACGAACCTGG |
CGGCCTATGT |
GCCCCTGCTG |
ACCCAGGGCT |
GGGCGGAGAT |
CCTGGTCCGG |
AGGCCCACAG |
GTACTGGGCG |
|
| 32401 |
GGGCTGGCCT |
GAGCGCCATC |
TTTCTGCCAG |
TCACCCACAG |
AGCTGTGGAC |
ACTCAGGGGC |
GATTGCAGAC |
TTGGCCCTCT |
|
| 32481 |
TGGGATATTT |
GGGGGTAACT |
TTTGTTTTTT |
TTTTGAGACA |
GAGTCTTGCT |
CTGTGGCCCA |
CGCTGGAACG |
CAGTGGCGCA |
|
| 32561 |
ATCTCGGCTC |
ACTGCAAGCT |
CCACCTCCCG |
GGTTCACGCC |
ATTCTCCTGC |
CTCAGCCTCC |
CGAGTAGCTG |
GGACCACAGG |
|
| 32641 |
CGCCCGCCAC |
CACGCCTGGC |
CAATTTTTTT |
GTATTTCTAG |
TAGAGATGGG |
GTTTCACTGT |
GTTAGCCAGG |
ATGGTCTCAA |
|
| 32721 |
TCTCCTGACC |
TCGTGATCCG |
CCCGCCTTGG |
CCTCCCAAAG |
TGCTGGGATT |
ACAGGCGTGA |
GCCACCGCGC |
CCAGCCATTT |
|
| 32801 |
GGGGGTAACT |
TGTAAGTCTC |
CAGAGGTGAG |
CTGTGAGGGG |
CGATCCAGGT |
GGCTGAGGTG |
GGGCAGGGGC |
CTGTGGCGAA |
|
| 32881 |
CCAAGTGACT |
TCCATGGCAG |
AGAGTTGCCC |
TCCCCGCCTG |
GAGGCTGCAA |
GTCCGAGACC |
AAGGTGCTCC |
TCGGCAGGAG |
|
| 32961 |
GTGCTCCTCA |
GAGGCCTCAA |
TCCTTGGCAT |
GCAGTTGGTT |
TTTTCCCTGT |
GTCCTCACAG |
GCTCTTTCCT |
GGATGTCTGC |
|
| 33041 |
GTGTTAATCT |
CCTCTTGGGA |
GGAAACCGGT |
CATGGCTTAG |
GGTCCGCTCT |
GGTCCCTTGC |
TAGCCGTAAT |
TAGCTTTCTG |
|
| 33121 |
AAACCCAGTC |
TCCAGAGACA |
GTCCCGTTCT |
GAGTTCCTGG |
GGTTGGGACT |
AAAGCATACC |
AACATGGGGG |
CACAGCTCAG |
|
| 33201 |
CCTGTTCCCA |
GGGGCAGAGG |
GAGCCCCCGC |
AGAGGCCCAG |
AGCCCAGGGA |
CAGAGGGAGG |
CCTTTGCAGA |
GGCCCAGAGC |
|
| 33281 |
CCAGGGGCGC |
CTGGGTGTGC |
CGTGGCTGAG |
GGGTGCAAAG |
AGTAGGGGTT |
CCAGCCCTCG |
TGGAGGCCTT |
GGGTCCGGAC |
|
| 33361 |
TGTGAGGCTG |
TGGGCTGGAG |
GCCGCTGCTC |
TGAGGTGCCT |
GGCGGAGCCT |
GGCCTCGAGG |
CAGGGGCTGA |
GCGGGGCAGC |
|
| 33441 |
AGGGTGGGTG |
GCCGTCAGAG |
CAGCGCTGGC |
TCCGACATCG |
TGGTCCTGAG |
GATTGTGGGA |
GGGAGCATGA |
GGGCAAAACC |
|
| 33521 |
AGGGCCCAGG |
CCAGGAGGCC |
CCTGGGGGGC |
CAGAGATGGG |
TAAGGGGAGG |
TACTGGCCTC |
AGGCCAAAGG |
TGCTGCCGCC |
|
| 33601 |
TCCGCAGGGA |
ACACCAGCTG |
GCTGATGAGC |
CTGGAGAACC |
CGCTCAGCCC |
TTTCTCCTCG |
GACATCAACA |
ACATGCCCCT |
|
| 33681 |
GCAGGAGCTG |
TCTAACGCCC |
TCATGGCGGC |
TGAGCGCTTC |
AAGGAGCACC |
GGGACACAGC |
CCTGTACAAG |
TCACTGTCGG |
|
| 33761 |
TGCCGGCAGC |
CAGCACGGCC |
AAACCCCCTC |
CTCTGCCTCG |
CTCCAACACA |
GGTGAGTGGC |
ATGGCGGGCC |
TTGGCACGGG |
|
| 33841 |
CTCTGCTCCC |
ACTGGCCTGG |
TGCTCCCGGT |
GACGGCAATG |
TGGCTCCTCT |
CTGCTGAGGG |
CGCCCACACG |
GCTGGGAGTG |
|
| 33921 |
GTCCCTGGCC |
TGCCTCAGCA |
CCATTGTTCT |
CCGGTGTTTG |
GGAGGAGGCT |
GACCCGTGGG |
AGGTGTCTGC |
CCTGCTCAGG |
|
| 34001 |
AAGCTGGGGC |
TGGCAGCTTC |
AGAAGCAGTA |
GGGGCCCTGT |
GGAGCCTCTG |
CCCAGCATCC |
TCCGTGGGGA |
GTCCAGCACT |
|
| 34081 |
GCGGGCTCCA |
GGAGGCTCTG |
CGGCAGCCTC |
CCTCCCTGCC |
TGGGCCCAGG |
TTTGGACACC |
TGAGCCCGCC |
TGCGCACTCT |
|
| 34161 |
GGGCCCCCAC |
CCCACTCGGC |
ACCGTGCTTC |
TCGCCAGGCC |
CTCTGGCTCT |
TCCCTGTGGC |
TGCAGATGGC |
ACTTAGCGGC |
|
| 34241 |
CTAGGACGTC |
TATTCACGGG |
AGGAGGGAGG |
CACTGCCCTC |
CTCAGGTCTG |
CCCAAGCAGC |
TTGTAGCTAG |
CACTGGGCCC |
|
| 34321 |
CGTGCGCGCC |
CCTGCCGGCC |
GCTGGCCCTG |
CCCTCTCTCC |
TCTGCAGGCA |
CGGGGCCTGT |
GCTCTCTGCT |
CGACCTGTGT |
|
| 34401 |
GTAGCCCCTC |
CTCCTGCTGA |
CGTGGCCGCA |
CACGGCCTTC |
CCTTGCAGTG |
GCCTCTTTCT |
CCTCCCTGTA |
CCAGTCCAGC |
|
| 34481 |
TGCCAAGGAC |
AGCTGCACAG |
GAGCGTTTCC |
TGGGCAGGTA |
TCGCCTCTCA |
GAGGGAAGCG |
GTTGGCTGCA |
GAGCGCCACT |
|
| 34561 |
CTGCCTCATA |
GGTGCTGTGC |
TCGTCGCCTC |
ATCCGCCCAC |
CCCCATGGTC |
CGTCTGCCTC |
CATTGCCCTG |
GGGAGCAGGT |
|
| 34641 |
CCCGACTCGC |
ATGAGGACGT |
CTGTGCAGAA |
TGTCTTTGGC |
TTGGCCAGCG |
GGATCCCCTT |
GACTTGGTCC |
CTTTGTGGCT |
|
| 34721 |
GAGCCCTGTT |
CCCACGCTGT |
GCGAGCACTC |
CCGGCCCAGC |
TTCAGGCCTG |
AGGGGTGGGG |
GTGGCCTGAG |
TCTCCATGGT |
|
| 34801 |
GACATCAGCT |
GAGCTGCAGA |
CTCTGATGGG |
TGGCAGCTGT |
TTAGGGGGAA |
GCCCACCCCT |
GGGCCTGCAC |
CGAGCGGGCC |
|
| 34881 |
TTGCCCTGGC |
CTTTGGTGGC |
TCCCCTGGCC |
TCTGGAACCC |
ACAGATGGGG |
CTGCCTCAAG |
TCCCAGGTTG |
ACCAGGGGCC |
|
| 34961 |
CTGCAGACCG |
ACCTCTGCCT |
GTTGCCCCCA |
AGCCCTGGTG |
GGGAGTGCTG |
TGACCTGCAT |
GGTGCTCCCC |
TGCCAGGTCT |
|
| 35041 |
CCACGTGCAG |
ACGAGCTGGT |
TTGGAAGGGC |
TGCGTGGGAC |
GGGCCCTGGG |
GTGGCTGACT |
GCGCGTGTGC |
AGGGCTGTGG |
|
| 35121 |
GGCGCCCGGG |
GGCTGTGATG |
GTCCCCTCTG |
TTGCTGCTTC |
TACTTCCTCT |
CCCCCTGTCC |
TGACGCTGGC |
ACAGGAAATG |
|
| 35201 |
CTGCTTTGGG |
ACCTCCCACC |
CTCTCTCCTT |
AGCGTCCCCA |
GCTGTGGGTC |
TGGCTTGGAG |
TTGGAGGGTG |
AGCCTCTGCT |
|
| 35281 |
CTTGGGAGCA |
GTCTGTTTGC |
AAACAGGGAC |
TTCCCCCACG |
TCACGGAGTC |
TCCGCAGCTC |
TCCTCGGTTA |
CGAGGGCTGG |
|
| 35361 |
TTTCAGGCTC |
CCGCTCTTTT |
AGAGCTGAGG |
CCCGTCGGGC |
GGAGAGCGTC |
TTGCCCCTGC |
CTACCTGGAG |
GCACAGGGGT |
|
| 35441 |
GGCTGCTGGT |
GGACACTAGG |
GTGGGCAGAG |
CCGATTGCCT |
GCCCAACCCC |
CGGGCACTCA |
TGCAGGAGAG |
GCCTGTGTCG |
|
| 35521 |
GGGTCACGTG |
CAGGCCTTCC |
CAGCGTCCTC |
CCTGCCCGCT |
CGGTGGATGG |
CAGCAGTAAG |
CAGAGCCCTG |
GGGAGGCTCG |
|
| 35601 |
CAGGGCTGCT |
GTCCCTCTGG |
TCAGGAGAAG |
GCTGGTTCTC |
GGAGGCCACG |
TCAGGGCCAG |
GGCCTGGCCC |
AGCCCCACAT |
|
| 35681 |
CCAGCAGCCC |
CGTCTGTGTC |
CTCCCAGACT |
CCGCCGTGGT |
CATGGAGGAG |
GGAAGTCCGG |
GCGAGGTTCC |
TGTGCTGGTG |
|
| 35761 |
GAGCCCCCAG |
GGTTGGAGGA |
CGTTGAGGCA |
GCGCTAGGCA |
TGGACAGGCG |
CACGGATGCC |
TACAGCAGGG |
TGAGTGTGGC |
|
| 35841 |
TCAGAGCCTG |
GACCCTGCTG |
ACCTCGGGGG |
GCTCCTTAGG |
GGAGGCAGGG |
CTCTGCGTGG |
GTGTGCCTGC |
ACCCTGGGAA |
|
| 35921 |
CTGGCTCTGA |
ACTTGGGGGA |
GATGTTCTTC |
CACATCCCTC |
GTGCACAGAC |
GGTCTGCACT |
TTGCAGCCAT |
CCACCTGGGC |
|
| 36001 |
CGGCCCTGGC |
TGCTGGGCAG |
CCTGTGGTCT |
CAGGGGATGC |
TGATACCTCT |
GCTCACGCAG |
TGTGGGGCAC |
AGCTGGTGGC |
|
| 36081 |
AGTGCTGCTG |
CGTCAACGGG |
CGGGGGCCGT |
AGCCTGGTGC |
TCGGGCTGGT |
CTGTGGCCCT |
GGGATGGAGG |
ACAGATAGGG |
|
| 36161 |
CCTCACCACC |
TCCAGGTCAA |
CCCCAGGTGG |
GCTCGAGGGT |
GCCTGCTGAC |
AGGGGTTCTC |
TTTGGGATGG |
TCCTTTCTAG |
|
| 36241 |
TCGTCCTCAG |
TCTCCAGCCA |
GGAGGAGAAG |
TCGCTCCACG |
CGGAGGAGCT |
GGTTGGCAGG |
GGCATCCCCA |
TCGAGCGAGT |
|
| 36321 |
CGTCTCCTCG |
GAGGGTGGCC |
GGCCCTCTGT |
GGACCTCTCC |
TTCCAGCCCT |
CGCAGCCCCT |
GAGCAAGTCC |
AGCTCCTCTC |
|
| 36401 |
CCGAGCTGCA |
GACTCTGCAG |
GACATCCTCG |
GGGACCCTGG |
GGACAAGGCC |
GACGTGGGCC |
GGCTGAGCCC |
TGAGGTTAAG |
|
| 36481 |
GCCCGGTCAC |
AGTCAGGGAC |
CCTGGACGGG |
GAAAGTGCTG |
CCTGGTCGGC |
CTCGGGCGAA |
GACAGTCGGG |
GCCAGCCCGA |
|
| 36561 |
GGGTCCCTTG |
CCTTCCAGCT |
CCCCCCGCTC |
GCCCAGTGGC |
CTCCGGCCCC |
GAGGTTACAC |
CATCTCCGAC |
TCGGCCCCAT |
|
| 36641 |
CACGCAGGGG |
CAAGAGAGTA |
GAGAGGGACG |
CCTTAAAGAG |
CAGAGCCACA |
GCCTCCAATG |
CAGAGAAAGT |
GCCAGGCATC |
|
| 36721 |
AACCCCAGGT |
GGGCCTCTTG |
CTTCCGGGCG |
GGGCTCCTGA |
CACCTCTCCT |
GCGGGAACCT |
GGTGCCTCAC |
TTGCCCCAGG |
|
| 36801 |
CCGAGCGGGC |
TGGGGTGGGG |
TCCTCGCCTG |
TGCCCTAGGG |
CTGGCTGGAA |
CCCCTGGGAG |
GGCGGTGGAG |
TGGGAGATGG |
|
| 36881 |
CCAGGCTCTG |
TGTTCCTCCC |
TGTGGGCTGT |
GGCTGCCCTG |
GCCAGGCCCT |
CACCTGGGTG |
CCCACCATCC |
CCTCCCTGTG |
|
| 36961 |
CAGTTTCGTG |
TTCCTGCAGC |
TCTACCATTC |
CCCCTTCTTT |
GGCGACGAGT |
CAAACAAGCC |
AATCCTGCTG |
CCCAATGAGG |
|
| 37041 |
TAGGCGTGGC |
CTCCCTCTCC |
TGCATCCGCT |
GGAGCTGTGT |
GGCTCGGGTG |
AATGGTGGGG |
GGCCCAGCTC |
TGCTGCTGGG |
|
| 37121 |
AGCTCAGGCT |
TGCAGAGGGC |
TCTGGCCTAA |
GCTCCCTGTG |
GCAGCCTGCC |
GTGACCGGCC |
TGGGTGGGGC |
GGCCTCCTGT |
|
| 37201 |
GGACGGGCGT |
CTGGGGCTCA |
GGCAGGGCTC |
TGTGTGCCAC |
AGTCACAGTC |
CTTTGAGCGG |
TCGGTGCAGC |
TCCTCGACCA |
|
| 37281 |
GATCCCATCA |
TACGACACCC |
ACAAGATCGC |
CGTCCTGTAT |
GTTGGAGAAG |
GCCAGGTGAG |
GCTGCGGGGC |
CGGCCTAGGT |
|
| 37361 |
GCCTGGACAG |
GGCCAGCTGG |
GCCTCAGCCT |
GCAGTGGGTA |
GGGAGTCTGG |
GCCCCCAACG |
CCCCACAGAG |
CTCAACACTG |
|
| 37441 |
CCGGGTCCCC |
TACAGCATGA |
AGTGCTCATT |
GAGCTCTGTG |
CCAGGTGCTG |
CTCTGAGTGC |
TGGGGACCCC |
GGTGCGAGTG |
|
| 37521 |
ACAGGTTAGC |
GTGGGAGCAC |
CCGGCACACC |
AAGGAGTGGG |
AAGGACTGGG |
CGGGTGGCAC |
CGGTCGCAGG |
GCTGGGGAGG |
|
| 37601 |
GCGCTGTTGG |
TCAGTGAGCT |
GACAGCTGAG |
TGGTGAGGGA |
GCGGGCAGGG |
GGAGCCTGCA |
TAAGGGGTGG |
GGGCATCCCA |
|
| 37681 |
CACACCAGCA |
GCGGGGGCCG |
GGCGCACCCT |
GCCCAGCTTG |
AGCACTGGTG |
CTGGGCGAGC |
ACGGGAGCCG |
ACAGGATGGG |
|
| 37761 |
CAGCCTCAGC |
GCCCTATAGG |
CTGCACCTTC |
ATCCCAAGGG |
AAAGGGCAGG |
GCCTGGGCTG |
CTTCTGAGCA |
GAGGGCACAT |
|
| 37841 |
GGCCTGACTC |
CGCCCAGTCT |
CAGTGAGTCC |
CTCCTGCTGT |
GTGGCTCGAG |
GAGGTGGGTG |
GTGATGGTTC |
CCGTGGGAGT |
|
| 37921 |
GGGGTAGGCC |
CCTGGGGGCA |
GGCTGCTGAG |
GGGCCAGGGC |
CCCGGGTGTG |
CTTTGAGTGT |
GGAGCTCCCT |
GATTTTGCCG |
|
| 38001 |
GCCAGGCACA |
CACGGGGCTG |
AGGGAAGAGA |
GGGAGTCAAG |
GATGACACCC |
GATGTCTGGC |
CTGGGTGGCT |
GCTGGAATGG |
|
| 38081 |
ATGGTCTTGT |
CTGCCTCAGG |
GATCAGAGTG |
GGGCTCCCGG |
CAGAGCCTGC |
TGGGCACCCC |
CACCCTCTGC |
GGGGCAGGGC |
|
| 38161 |
CCGGCCCGGG |
AGTGATGCCA |
CCCTGCCTCT |
CCCCTCTCCC |
CACAGAGCAA |
CAGCGAGCTC |
GCCATCCTGT |
CCAATGAGCA |
|
| 38241 |
TGGCTCCTAC |
AGGTACACGG |
AGTTCCTGAC |
GGGCCTGGGC |
CGGCTCATCG |
AGCTGAAGGA |
CTGCCAGCCG |
GACAAGGTGT |
|
| 38321 |
ACCTGGGAGG |
CCTGGACGTG |
TGTGGTGAGG |
ACGGCCAGTT |
CACCTACTGC |
TGGCACGATG |
ACATCATGCA |
AGGTACGGCC |
|
| 38401 |
TGGCGCCTAC |
CCGCTCCTGC |
TGCCCCAGGC |
CTCAGGGCAC |
GGCTCCCATC |
CAGTCCTGCT |
ACCCCACGCC |
CTGGGGCATG |
|
| 38481 |
GCCCTGGCAC |
CCCCACCTGC |
TCCAGCTCCC |
CACGCCTCAG |
GTTCCGAGCC |
TAACAGCGTG |
GGCATGGAGG |
CAGTGATGGG |
|
| 38561 |
GCTGGTGGCT |
TTGCGTCCCA |
AAGCCCTGCC |
CCTGGGGAGA |
GCCGAGGACC |
ACTGGCCAGG |
CACCAGAGGA |
CGTGGTCCCC |
|
| 38641 |
GCAGGCCCCC |
AGAGCCCCTG |
GAGTAATCAG |
GAGGTGCCCC |
AGTGCAAGGC |
ACAGAGGGCC |
TCAGCACTGG |
CCCCACAAAC |
|
| 38721 |
CCATCCGGCC |
CTGCTCACCC |
TCAGCCGTCT |
TCCACATCGC |
CACCCTGATG |
CCCACCAAGG |
ACGTGGACAA |
GCACCGCTGC |
|
| 38801 |
GACAAGAAGC |
GCCACCTGGG |
CAACGACTTT |
GTGTCCATTG |
TCTACAATGA |
CTCCGGTGAG |
GACTTCAAGC |
TTGGCACCAT |
|
| 38881 |
CAAGGTGAGT |
GAGGGGCCGT |
CAGTGAGGCT |
GGGCCCCAGG |
CAGGTGCCCA |
CTGCTGTGTC |
CCGGGTTGGT |
GGCAGGTCCT |
|
| 38961 |
CCTCCCTGAG |
CTTCGGTCAC |
GAGGAGCAGG |
AGGAGAGGCC |
GCAGTGCTCA |
GGGCCCCGTG |
GGCACGAGCT |
TCACCCCGAG |
|
| 39041 |
CCTGCGTTGT |
GTCCTCTGTG |
CCCTGAAGCC |
TGTGGCGCCT |
GCTGCTGAGT |
GTCTGTCAGG |
AGTAACTGGC |
AAGTGCAGAC |
|
| 39121 |
TGGGTGTGCT |
GGGTGGGCAC |
AGTGTAGTTG |
GTGCTTCCTG |
TCTGTCCGGC |
GCGGCCCTTG |
GGCCCCCACC |
ATCTCCCCAG |
|
| 39201 |
TGGCAGCTGT |
CAGGCTGCTC |
AGTTGGTTAT |
CGCCACGCAC |
CACTAGGCAG |
CAACCAGCGT |
CACCCTCTTC |
CTGGAGGTGG |
|
| 39281 |
GCTGGGTCGG |
CCAGTGTCAC |
AGCACGGTCC |
GGGTGAGCCC |
CAGCATGGCG |
GGGAGAGCTG |
GCATGGCCCA |
GGCAGGGCAG |
|
| 39361 |
ATAGGCTGGA |
GGCCTCACTC |
CAAGGGCCCC |
AGGATGCTGA |
GGCAGCCACT |
GAACCAAAAC |
CCCGGGGCTG |
GTAGTCAGAG |
|
| 39441 |
TCCAGGAGGG |
GCAGGAGCAT |
AGGGAGGTGG |
GCTCTGCTAG |
ATGCCAAGAC |
AACCAGTTGG |
GGGGGGGGGG |
GCACCTGGGC |
|
| 39521 |
GGCTGAGGAG |
GGTGTGGTGG |
TGCCGAGATG |
GGGTGCACGG |
CTCACTTCAT |
GGCTGGGCAG |
ACGGATTCGG |
ACGTGTGGCT |
|
| 39601 |
GCAGACACCC |
TGGGGGCCCC |
AGTGAGTGGA |
GGTGCCCCAG |
CAATTAGAGG |
TGTCTTGCCT |
GTGGCTGCAG |
CATATGTGGG |
|
| 39681 |
TGCTGCGCCC |
AGATGTGGAG |
GGGGCTTGGC |
CTGGGGGAGG |
CCAGACAAAC |
ACAGCCCCGC |
TGCCAGAGGG |
GAAAGTTCAG |
|
| 39761 |
GGGCAGATGC |
TGCCCATGGA |
GCTGACAGGT |
GTCTAGCAGT |
GCAACCAGGC |
AGTAGCCGAG |
ATCAGCCTTC |
AGCACACGCT |
|
| 39841 |
GTGTGCGGGG |
ATGACCCTTT |
CTCTTGTCCG |
GGCAGGGCCA |
GTTCAACTTT |
GTCCACGTGA |
TCGTCACCCC |
GCTGGACTAC |
|
| 39921 |
GAGTGCAACC |
TGGTGTCCCT |
GCAGTGCAGG |
AAAGGTAGGG |
CCGGGTGGGG |
CCCTGCAGTG |
CAGGAAAGGT |
AGGGCCGGGT |
|
| 40001 |
GGGGCCCTGC |
AGTGTGGCGC |
CAAGAGCCCT |
GGGCCTGGCG |
TGACCACCAA |
GTCTCCCCAG |
ACATGGAGGG |
CCTTGTGGAC |
|
| 40081 |
ACCAGCGTGG |
CCAAGATCGT |
GTCTGACCGC |
AACCTGCCCT |
TCGTGGCCCG |
CCAGATGGCC |
CTGCACGCAA |
ATGTGAGTGG |
|
| 40161 |
GGGTGGGTCC |
AGGCGTGAGC |
TGGTGGGACA |
GGCCCAGGTG |
CCACCTGATA |
GTGAGCTCAC |
CCCCTGCCTA |
CGTCCCCAGA |
|
| 40241 |
TGGCCTCACA |
GGTGCATCAT |
AGCCGCTCCA |
ACCCCACCGA |
TATCTACCCC |
TCCAAGTGGA |
TTGCCCGGCT |
CCGCCACATC |
|
| 40321 |
AAGCGGCTCC |
GCCAGCGGGT |
AGGGAATATG |
GGGCTCCCTC |
AGCGGGGTGT |
GCTGGCTGCC |
CAAGCTGTGG |
GGCGGGTGTG |
|
| 40401 |
TGGGCAGAGC |
GGTTGCCACG |
CCTCCCAGAC |
TTACTGCCCA |
AGCCGCCTCT |
GCCTTCAGAT |
CTGCGAGGAA |
GCCGCCTACT |
|
| 40481 |
CCAACCCCAG |
CCTACCTCTG |
GTGCACCCTC |
CGTCCCATAG |
CAAAGCCCCT |
GCACAGACTC |
CAGCCGAGCC |
CACACCTGGC |
|
| 40561 |
TATGAGGTGG |
GCCAGCGGAA |
GCGCCTCATC |
TCCTCGGTGG |
AGGACTTCAC |
CGAGTTTGTG |
TGAGGCCGGG |
GCCCTCCCTC |
|
| 40641 |
CTGCACTGGC |
CTTGGACGGT |
ATTGCCTGTC |
AGTGAAATAA |
ATAAAGTCCT |
GACCCCAGTG |
CACAGACATA |
GAGGCACAGA |
|
| 40721 |
TTGC |
|
|
|
|
|
|
|
|
|
|
|
|
>ref|Gene_ID:7249|TSC2|NC_000016.9:2097989...2138712 (+)
TCCGGCGGCGTCCCGGGGCCAGGGGGGTGCGCCTTTCTCCGCGTCGGGGCGGCCCGGAGCGCGGTGGCGCGGCGCGGGGT
AAGTGGCGGTCCCCACGGGGCAAGTGGCGGTCCCCACGGGGCAGCGGCCTAGAGAGGCGGACCCCGCAGTGTCCGGGTCC
CGGGCCCTCACCCGCGCCCACTGCAACCCGACTCCGGAGCTCCGAGCATCCCTTAGTTTTAAGTCATGGCGGGTGCGAAC
GGGTCTCTGCTGCAGGCGGCTCCGTGACAGCTCCTGCTTCACATGGGTAGAGGAGAGACGGCAAACGTCGGGGCTCCCAG
GACTTCGCGGCGGCAGTCCTAACCCGTGCACTGAGTCGGGCGGGGCGGGCGGCAGCGTCTGAGTAGAGAGCTCTCTAGAC
CAGGCCTGGTGTCTCCCGGGCTTTCCTAGGTGCCTGTTTGCGAGCTGGTCAGCTGGGCTGTAGTTGAGTTCTCCCAGGGA
GTGTGGGAGGAAAGGTTATGCCCACCAGAGACCCAGGGTCCTGACGGCTGGAGGTCCGCAGTGGGGAAGGTGGGCAGAGG
TGTTGCTCAGATGTCCCCATTCCTGTTTCGTTTGCACAGAGGGGTTTTCTGGTGCGTCCTGGTCCACCATGGCCAAACCA
ACAAGCAAAGATTCAGGCTTGAAGGAGAAGTTTAAGATTCTGTTGGGACTGGGAACACCGAGGCCAAATCCCAGGTCTGC
AGAGGGTAAACAGACGGAGTTTATCATCACCGCGGAAATACTGAGAGTGAGTGAGCTACCTGTGTCTTTGCTAGGCTAGA
GGGAAATGCAGAGAAGGCTGGGTTTGGTCTTGCACCAGGTTCTGTGGGAGACGGGTTGCTGGCAACTGTCTACACAGGAA
TGCTGTCTCCAGTACTTGGAGGCCGACATGTCCTTCCTCAGGAGACTTCGAAAGTCAGGATCTTGGTGACCTGGTTCAGG
CACACTTGAGTTACTATTCAGATGTTGATGAAAGAAAGCCCATCTTATAGATGAGGCCTGAGTATCATCATCTTCACAGG
TAAGGATATGTCCAGGTGTTACATGATAAGATGTGAGTTCCTGGGAGAAGTAGGTTCTTTATTTTATTTTTTTTTTGAGA
CTGAGTCTTGCTCTGTTGCCTAGGCTGGAGTGCAGTGGCACAATCTCTGCTCGCTGCTACCTCTGCCTCCCAGTTTCAAG
TGGTTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGACACGTGCCACCACACCCATTTAATTTTTGTATTTTTAG
TAGAGATGGAGTTTCACTATCTTGGCCAGGCTGGTCTTGAACTGCTGACCTCAGGTGATCTGCCCGCTTTGGCCTCCCAA
AGTGCTGGGATTACAGGCATGAGCCATCGCACATGGGCTAGGTCGTTATCTTTTATGTGTGTTTGTGTCTTTGTCACACA
TGCCTGGCATTGTGTTTTGCCCATGAGTAAATGCTGAATTTTTGCACTTGTAAAGTTTTCTACTTAGAAACAACTAAAAC
GTTCATCAACTGATGAATAAAATATAGTCCATCCTGGCTGGGTGCGGTGGCTCACGCCTGTCATCCCAGCACTTTGGGAG
GCCGAGGCGGGTGGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACATGGCGAAACCCCGTCTCTACTAAAAA
TACCAAAAATTAGCCGGTCATAGTGGTGGGCGCCTGTAATTCCAGCTACTCGGGGGGCTGAGACGAGAATTGCTTGAACC
CGGGAGGCGGAGGTTTCAGTGAGCCGTGATCGCGCCACTGCACTCCATCCTGGGGAAGAAGAGCAAAACTCCGTCTAAAA
AAAAATTGTGCAGTTTGAAATTGTATTTCATGTTATGTTTTATCTCAATACAACATTTGCAGTTGTGAAAAAAAATTGCA
CATTCTCAACTCCTCGGGATGGAGCAGTAAAGCCCCTCAGTAAATCTTTTTTTTTTTTTTTTTTTGAGACCGAGTTTCGC
TCTTGTCACCCAGGCTGGAGCGCAGGGGCGCGATCTCGGCTCACTGCAATCTCCGCCTCCTGGGTTCAAGGGATTCTCCT
GCCTCACTCTCCCGAGTAGCTGGGATTATAGACGCCCACCACCACGCCCAGCAAATTTTTTGTATTTTTAGTAGAGACAG
GGTTTCATCATGTTGGGCAGGCTGGTCTCAAACTCCTGACCTCTGGTGATCCACCTGCCTTGGCCCCCCAAAGTGCAGGG
ATTACAGGCCTGAGCCACCGCGGCTCGTCAAGTGAATCTTGATTCCAGAAAGATCTGTTTTAAGTCTCTAGTCTGGAAAA
TGCAGTGGGAGTCTTTAGGTGGTTTGTGACTTGCAGTTAAGGAGACCGTGGCCTGAGCACTGGCCCCTTTTTCTTCTTTC
ATCTCTCTCCAGGAACTGAGCATGGAATGTGGCCTCAACAATCGCATCCGGATGATAGGGCAGATTTGTGAAGTCGCAAA
AACCAAGAAATTTGAAGAGGTAGGTTTATCCAGTTGAGCTACTAGAGAGAGGCACGTAGACTATTCAGAGCCTGAGTTTG
CTTTTTTTAGGAACATGGTTGACAGCTGACTGCCGATGATCTGGTTTGCACTTTTTTTTTTTTTTTTTTTTTGAGATGGA
GTCTTGCTCTGTCGCCCAGGCTGGCACAATCTTGGCTCACTGCAGCCTCTGCCTCCTGGGTTCAAGCAGTTCTCCTGCCT
CAGCCTCCTGAGTAGCTGGGATTACAGGCACGCGCCACCACACCCGGCTTTTTGTATTTTTAGTAGAGACGGGGTTTCGC
CATGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCGTGAACCATATGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCG
TGAGCCACTGCGCCCAGCCAGTTTGCACTGTTTTAGGGGAATTTAGCTTTCATCGTAGTGATGGGGAAGCTACTGGAAAT
GCCCCGAATACAACCTTGAGGGACCAATCAAGCGTGGAAATGGGGAGCAAAGGGATTAGGCTTTTCTAGCAACACCAGAA
AGGATTTCTATGCCGAGCGGGGGTGCGGGGGCTTATGCCTGTAATCCTAGGACTTTGGGAGGCCGAGGTGGGTGGATCAC
GAGGTCAGGAGTTCAAGACCACTCTGGCCAACATGGCGAAACCCCGTCTGTACTAAAAGATGATGAGCCGGGCATGGTGG
CACATGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAGGCACAGGTTGCAGTGAGC
CGAGATCGCCCCACTGCACTCCAGTCTGGGTGACGGAGCAAGACTCTGTCTCAAAAAAAAAAAAAAGGAAGAGTTTGTAG
TGGCTGATAGAAACGCATGCTCACTCGCTCTCTCCTGTTACAAGTTCAGGCCAAGAAAAATCAAGAAAGGGTTTGTTCCA
CAGAGAACAATCCTAGGCACGCTGGTCTTGGTGCCATTTTGGGAGGGTGACTGGTCGGTGGTATTGGGCGACCTCACGGA
CATAGAAATATTTATTTTGGGCAAACATTGCCAGACTTTCCTGATGACTTGTGGACAGGACAGGAAGTGGTCATTTTGGG
AGTGCAGGTTGCTGGTAGAGCACCTGAGGGCTCTGCCCTTGCCTTGCCCAGCATTTGTGTGTGGGAGAGCAGTGAGACCT
GGACCTCTCATGCTCAGATCTGCTAAGAGGAGAGTGATTGCTACCTCTGCAGCAGCTCATCTGAAACGTGCTGGCCGTAC
GCTACCAAAGATAGGTGTAAAGAACAGGTGTCCTTAGCCGGGCGCAGTGGTTCACGCCTGTAATCCCAGCACTTTGGGAG
GCCAAGGTGGATGGATCACCTGAGGTGAGGAGTTCGAGACCCGCCTGGCCAATGTGGCAAAACCCTGTTTCTACTAAAGA
TACAAAAATTAGCTGGGCATGGTGTCGGGCACCTGTAATCCCAGCTACTTGGGAGGCTGAGGGAGGAGAATCGCTTAAAC
TCAGGAGGCAGAGGTTGTGGTGAGCTGAGATTGTGCCATTGCACTGCAGCCTGGGCAACAGAGCAAGACTGTCTCAGAAA
ACAAAAAAAAGAACAAGCGTCCTGCATCCTGTTCTGAAAGTTGTTTGTGTGGGTACGGGGCAGCCTGTGAGTGGATAAAT
AGGCCTCCGAGGCTGGGATGGTCCCGGGCCCTGTGTCCACGGATCTTTGCAGCTCAGGTTGCAACGGTAAGAGTATTGTC
AATGAGACAAAGGAGGTGAGAGTGCCAGTTGTCTGAATTGGTTGGGATGTTGGTCAGATGACATCTAAAAGAACACGGCC
ATTTTGTTATTATTTGGTTAGAGACAAGGTCTCACTCTGTCACCCAGGCCGGGGTGCAGTGTCACAATCATGGCTCACTA
CAGCCTCAACCTGCCAGGCTCACGTGATCCTCCTACTTTAGCCTCTCAAGTAGCTGGGACTACAGGCATGCAGCACCACG
CCTGGCTAAGTTTTGTATTTTTTGTCGTGACAGGGTCTCACTGTGTTGCCCAGGCTAGTCTGAAACTCCTGGGCTGACGT
GACCCTCTCCCCTCTGCCACCCGAAGTGCTGAGATTACAGGTGTGAGCCACCGCACTTGGCCAGAACACGGCCATTTTAG
TTCCCCTCCTTAGAGGAGTAAGGCCAGGAATGAGCCTGTGGTCTGAAAGCCGTGGCTGTTGGTTAATGTGGAGAAGGGAA
GGTGGTGAGAGCCAGCCCAAACCCCTGCCGAGTGAGACTGATTCTGGCAGCTTTAGGGAGCAGGGATGAGCCCCTCACAG
GCTGGGTGGTAGTTAGAGGAGGCAGATTTCAGAAGGCCACGCAGCGCTCTTTCTCAGCAGGTCAGGCAGGCAGCAGAGGT
CGGGCAGGGGCATGGGGTCGAGGGCCCGATGCTGGTGTGTTCACTAGAGGAGAGCCACAAGCAGGGATTCTGGGTCAGGT
GCAGGCCTAGGGCTTAGTGTGCACTTGTGGTTCTGAGACTGTCCCATGACTTCCTGCCAGCATTCCGGCAGCTCTAGTGG
GACTCCCTCCTGGTCCAGGTGAGGCCACCATTGCTGCCCTGGCTTGCTGCTGTCCTCTCAGCCCCCAGTCTGTCACCTGG
TGGGAGTTAAAGGGACCTGCTGGGGTTTGAGGAAGCTCTGAGCCGTTCCCTGTACGAAGCCTGTGGTCATCTCAGGCTGC
AGGAGACACAGGAGATACGAGCTTTGGAGGTGGGGCTCTCAGTCACAAGCCCCCGTTGTTCCTCCCTGTCCTCCGCTCAC
GGCACTGCTCCAGTTGCCGGGGCCAGGGTTCTTGGAGAGCACATCCTCACCGCTGTCCCCTCTGCTGGTGACAGCACGCA
GTGGAAGCACTCTGGAAGGCGGTCGCGGATCTGTTGCAGCCGGAGCGGCCGCTGGAGGCCCGGCACGCGGTGCTGGCTCT
GCTGAAGGCCATCGTGCAGGGGCAGGTAAGGCCCAGGGCGACGCTGGGATGGGTGACGTCAGGCTGCCCACTGACTGTCC
TGTCCCTGCTGGGCCGTGTTTGGACTCCTGCCTCGGTGAGTTGCTGGGCACAGGGTCTAGGGGCTGATGGGCTCTGGAGC
TGGATGGCCTGTGGGGTCTCCTGGTGTCATGAGGTCTGTGTGACCGTAGGCACTGCCTCCTCGCCTGTAAACAGATGGTC
ACTGCACCTTCCTCTTATGGGATGTTCTGGGGATCATATGAGGCAGTTCTCGCAGAGTGCTGAGATCGTACCTGGCAGCT
GGTGTGGGGCTACGGTGTTGTTTTGCCCTTGCACCCTTTCGGGGCCACTCCCCTGCTCACTGCATTCCATCTGTGCTGGT
CTTGGCTGACCCTGAACACCCAGGCCTCTTGGTGTTCCTGCCTCCCCTGGTCGGCCACTTCTACTCCTTCATGTCCCAGC
TGCTCAGAAGGGCCGTCCACTCTCACAGGCTCTCCTGGGTTTCCCCCACTCAGGCCTTGTCCTCAGTCTCTGAGCACAAG
GCTGTCTGCCCTGCACCGAGTGCAGGGGTCGGGCAGGAGCTGTGTCATCCCCTGCTCTGCGCCACCCGCTGTGCCAGGTC
CCGACACACAGCAGTTGCTCCCCATACGCCGCTCTGCGGTCGGCCGGTGCATCCGGCCCCCTGCCCTGTACAATGCTGAT
GCTGCAGACCTGTCTCTTGCAGGGCGCCTCTGTGGGAAGGAGAGGGGTCCAGGGCTGGAGTCCGGGTGCCCCTGCACTTC
AGGGACTTCTTGGCAGCCGTGTGGGCGACGCTGGCAGGCTCTGCTGATCCTGTGGCTTTTGTCTTTAGGGCGAGCGTTTG
GGGGTCCTCAGAGCCCTCTTCTTTAAGGTCATCAAGGATTACCCTTCCAACGAAGACCTTCACGAAAGGCTGGAGGTTTT
CAAGGCCCTCACAGACAATGGGAGACACATCACCTACTTGGAGGAAGAGCTGGGTGGGTGCCACCTTGGGTTGGAGGTTT
CTCTGGCCTTGACGATCAAGTGTAACCTGGATGGGAAGGACCTGGGGCTGGGGAGGGGCTGCCGTTCTCAGGGATGGCCT
GCAGCGGGTATGCCCACCCTGCTTCATGCACCTGGGCTCACCTGCGTGGCCGGAGTGCCCCTGAGGCACGTGTTAAAAAT
GCAGAGTCCTGGCCTTCACCCCAGACCTGCTGACTGTGAGTCTCTGGGGCTTGGGGCCTCCGAACACCTCTGCAACGGCA
GGAGCTGGGCGAGTTCTGTCACTGGGAGGTGGTGCTGCTGACTTGGTCTCAACCGGAGCGTACTGGTCCCGTCTTCCTCC
TCCTTTCTCCACTTTGTGGACCTTCCTCCTGCCATCCTGTGGTGGGAGGTTTCCATTAGTCTTGGGTCTCTGTGTCATGA
TTCTGGGAAGTAGAGAAAGAGGAGGAAGAGATCGGTCTGACTCTGGCTTTGCTGTTCTGTCGCCCAGAAAAGGGCCTCAG
TGGCTGGGCTGCCTGCAGGACAGGTGCCGGCCAGGTGCCTACCGTCAGGTTTCCTGTCTGAGGTGACGTGGCCGGCAGCC
AAGTGTGCACACGTCTCCTCCGAGCCACTCTCTGCTGGGGGTGGGGAACGCCCAGGAGTCTGGTGATGTCGGCGTCTCCC
AGCCTCGGGTTGGGCCCTGAGTGTACGGCATACACACTTCTGCTGCCGCCTCGGCACAGACCCTCTGTGCAGCCCCAGGG
GCGGTAGATCCTAGTGTCCGTGCGTAGCCGGCCTGCCCTGGGCTCCCCTGAGCCTCTTCGGGCCCAGTGCGTGGTCTGTC
TGTTGCTGCCGGGGGACTGATGATGGGGTTTCTGGCAGTGACGGGTTTGGACACACTGTCCTGCGGCGGGAGGGGGAGGT
GAGTGGGAGATGTAGATTCGGCGTCCTCGCAAACTGCCGCCGCTTCTCCCCCAGCTGACTTTGTCCTGCAGTGGATGGAT
GTTGGCTTGTCCTCGGAATTCCTTCTGGTGCTGGTGAACTTGGTCAAATTCAATAGCTGTTACCTCGACGAGTACATCGC
AAGGATGGTTCAGTAAGAAAAGAATTGAGATCCTGTTCTGATAATGGTCCTAAGTTCAGCTCCGCAGTGAATAAAGTTGA
AACCACCAAAAAAATAGAGGTTGGGCTGGGCACAATGGCTCACGCCTGTAATCTCAGCACTTTGGGAGGCCGAGGCAGGC
GGATCACGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCC
GGGCATGGTGGTGGGAGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATTGCTTGAAACCGGAAGGCAGAGG
TTGCAGTGAGCGGAGATCGTGCCACTGCACTCCAGCCTGGGTGAAAGAGCAAAACTCCATCTCAAAAAAAAAAAAAAAAA
AAGAGAAGTACGTAGCTATCTTCTGTTTAGCTCTCATCTGATGTCTTGGTTATCTTTTTGTTGTTTGTTTAGAATGTTGC
ATGAGCTCTGTCTCACTCATGCTGAACACCCAGCACCGAGAGCAGTGGCTGGCGCACAGCAGGCACCTGAGTGCTTGTTG
GGTGGGTGGGACCCCCAGGGAGGATGAGCCATGCGTGTTATTGACGTCATAGAGTGACTAGACCACAGCCCGTGGTGGCT
CGGCCATCCAGGCAGTGCTGCCGGGACTGAGCTCGGTGCTCCCTGCAGGATGATCTGTCTGCTGTGCGTCCGGACCGCGT
CCTCTGTGGACATAGAGGTCAGTGCCTCCCCTCCCCAGGGCCGGCCCATTTCACCCTGGTTTCTGGGAGGCTGGGGCTTG
GGGGTTGAGCCCTGTGTGCCACCTGCTGGCTGTGTAGCCCTGGGCAAGCTGCTCGGTCTCTCTGAGCCTCAGGAGTCCCC
CATGTAAGTCAGGATAGCCGGGCGCCTCCATGTGGAGATGTAGCTCAGGGTGGATGACAGCATCAATGACCCACAGTGAC
AGGGACGTCAGGTGCTTCCCACATGCCCGCTTGCCCTGTGGCTTGGAGAGAGGGTGCCATGGCAGCGGGGAGAGGTGGCA
GCGCAGGCTGAAGGAGGTGGGAAGGAAGCCTGGGTGTCCTCTCCTGTGGGGAGGAGCTGGGGTAGGACGGGCGTGAGCCG
TCTCCCTCTCCACCAGGTCTCCCTGCAGGTGCTGGACGCCGTGGTCTGCTACAACTGCCTGCCGGCTGAGAGCCTCCCGC
TGTTCATCGTTACCCTCTGTCGCACCATCAACGTCAAGGAGCTCTGCGAGCCTTGCTGGAAGGTGGGGTTTCTGAAACTG
CTCTGGAAGGTTCCTGAGAGCACATGGATGGGACAAGGGCCATCCTGTCTCCCATGAATGGTTGTCTGATTCTTGGGGTG
GCCAGACAATGGCCTGTTGAGGGACGGCCAGTGTCATTTTCCCAGGCAGTTGAGCTGAGGTCAGGGTTTTGGTGGCATTT
TGAGAACCCTGCTGCCTCTGTCTTTGGGAGGAGATGGTGGCGAGCTGGCCGGACCTTGGGTGGCTATAGGGCAGCAGCCA
GGCGGGGCCAGCAGCGGGACTGGGGCTGGGGGCAGGGCTTATGCCTGCCAGCCCCTGACACGCATTGTGTCTCGCAGCTG
ATGCGGAACCTCCTTGGCACCCACCTGGGCCACAGCGCCATCTACAACATGTGCCACCTCATGGAGGACAGGTGAGTGTG
GTGGGTGGGGCGCAGGGCAGTGGAGGCCAGCACAGCCCTCGGGGCAGCTCCAGTGTCCCTTGCCAAGCACACACTGGCTT
AGAGAGTCCTTGTCCTCTCGGGCAGCTGTTCCAGAGGCTGCCACTAGAGCGAGGCCCATGACTTCTAGGATCCAGCCCCT
GTCCTCTCCTTCCTCTGTCAGTTCAACAGAATATCCACACCCAGCTCAGTGCCTGCCCCATGCTCGGACGTCCTCCAGCG
GTGCTCCCCAACTACTTAGCCTGTTACAAGGCGAGGCTCGGGGTCTTGGCTTGACGTTGCCCTTGCCCTCACCCCCACAG
CCAGGCTGTGGCCACTTTTGTTGCTTTAGCCATTAGAGATGGCTCAGCTCTGCCCACACCCTGGCCTCCCACCCATGCTG
CCAGCTCCCCCTCCTGCTCTCCTGTATCCATCCGCGCCTCCTGAAGCCCACTCCATGCAGCACCCGGGTGGCCTTTTTCT
GACACAGATATGTCGGTGTCACCCTTTGCTGGAAGCCAGGTGGTTCCCAGCGCCCTTGGGATGTAGGCTTCTCCTATGGA
ACCAGGCCCTGGGGCCAGCCCTGCCTCAGCCCTGCATCTCTCCCAGCCCTGCCTCGGCCCCTGCATCTCTCCCAGCCCTG
CCTCGGCCCCTGCATCTCTCCCAGCCCTGCCTCGGCCCCTGCATCTCTCCCAGCCCTGCCTCGGCCCCTGCATCTCTCCC
AGCCCTGCCTCGGCCCCTGCATCTCTCCCAGCCCTGCCTCGGCCCCTGCATCTCTCCCAGCCCTGCCTCGGCCCCTGCAT
CTCTCCCAGCCCTGCCTCGGCCCCTGCATCTCTCCCAGCCCTGCCTCGGCCCTGCATCTTTCCTTCCCTCCATCCTTGGA
ACCAGGCCCTGGGGCCCAGCCCTGCCTCAGCCCTGCATCTCTCCTAGCCCTGCCTCAGCCCCTGCATCTCTCCCTCCCTC
CTCCCGTAGAACCAGGCCCTGGGGGCCAGCCCTGCCTCAGCCTGCATCTCTCCCAGCCCTGCCCCACCCCCTGCATCTCT
CCTTTCCTCCATCTTGCCTTCTCCCCTCCACCAAGGGCTTGTGCATGCCCTGATTCCTCTTGCCAGCAGGTTCTTCCACC
TTTGCCGAGTTACTCTGTTTACTGAGGTCTTAGCGTGGTCACTGACTCCCCCACCTCCCTGAGTAGTTTTTGCTGTGGCT
TTCCTTCTTGGCTGTGATTGGAGGAAGAGATTTTGCGTTTACCTGGGAGATTATGTGGCTGGCGCCTGTCTCCCCCAGAC
TGCGAGGCTGTGGGCCATCCCTCTTGCCTGCTTCCTGTCCCTGGCATGACCTGTAGCTCACAGCGTGGTCAGCAGTGATG
GGCTGCCGCCTGTGCGCAGGAGTGAACAAGAGTGTTACTGCTGGCCTCTGTTCCCTGCCCTTCCCCAGCGGTGCTCCTGC
CCCCCCCAAGCACAGGGACCTCTGGGGCTGCTGCAGGAGCCTCGGCAACCTCACACATCCATGGCGGACCCTGGGACAGG
GCCCTGCTCACATTCCGTCTCTCTGGGGAACACTTTTAGAGCCTACATGGAGGACGCGCCCCTGCTGAGAGGAGCCGTGT
TTTTTGTGGGCATGGCTCTCTGGGGAGCCCACCGGCTCTATTCTCTCAGGAACTCGCCGACATCTGTGTTGCCATCATTT
TACCAGGTAAGGCGGTTTCTGTGTGCAGTGAGCTGGCAGGAACGGGAGAGCTCCCCTCACGCCTGCCCACCCATCCCACT
GGGGGTCCTGCTGCGGGGGCTGCGGTGGCATTTCTAGGCCTTTCCAGGCAGTTGCTTTGCAGCTGGGGGTGAGGTTTGGG
GCCCTTTGTAGGCTTTAGTCTTTTTTTTTTTTTTGAGAAGGAGTTCTGCTCTTTCTGCTTGGCTGACTGCAATCTCCGCC
TCCCGGATTCAAGTGATTCTATTGCCTCAGACTCCTGAGTAGCTGGGATTACAGGTGCCTGGTACCATGCCTGGCTAATT
TTGTGTTTTTAGTAGAGACGGGGTTTCGCCATGTTGGCCAGGCTGGTCTCGAATTCCTGACCTGAAGTGATCCACCCATC
TCAGACTCCCAAAGTGCTAGGATTACAGGCGTGAGCCACCATGCCTGGCCAAAGGCTTTTTTCTCTCTCTCTTTTTTTTT
TTTTTTTTTTTTGAGACAGAGTTTTACTCTTGTTGCCCAGGGTGGAGTGCAATGGTGCGATCTCGGCTCACTGCAACCTC
TGCCTCCCCAGTTCAAGCCATTCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGTGCCTGCCACAGTGCCTGGCTAAT
GGTTTTTTTTTTTTTTTTTTTTTTTTAATGGGACAGAGTTTCGCTCTTATTGCCCAGGCTGGAGTGCAATGGCGCGATCT
TGGCTCAGCGCAACCTCCGCCTCCCAGGTTCAAGCCATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTATAGGCATG
GGCCACTACACACAGCTAATTTTTTATTTTTAGTAGAGACTGGGTTTCTCCACATTGGTCAGGCTGGTCTCAAACTCCCG
ACCTCAGGTGATCCGCCAGCCTCAGCCTCCCAAAGTGCTGGAATTATAGGTATGAGTCACCGTGCCCGGCCAAGGCTAAT
GTTTTGTATTTTTATTAGAGATGGGGTTTCACCATGTTGGTCAGGCTGGTCTTGAACTCCTGACCTCAGGTGATCCACCC
GCCTTGGTCTCCCAAAGTGCTGAGATTATAGGCATGAGCCACTGCGCGCAGCCCAAAGGCTTTATTCTCAAGCAAACCTT
ACATCTTGCGAGTTTCACCTTCTGGAGTTGGCAGTGGAGGGGTGAACGCTGCCTCGGGGGTAGCCGTTCTCTTGCTGTTG
GCGGCTCTGTTTTGTCAAGTGCTGGTCTTGTCCTGTCTCTGCAATGACGCCGTGGCACAGACGCTGGTGGTACAGCTTCA
GTTTCCGCAGTGCCCCGTGATGACAGCGCTTTTTGTGTCCGTCCTCGTTCTGTGCTCACAGCTCCCTGGAGGGTGGGGCG
ATCACGTCGTCCTGGTTTTATAGTGATGAGCTGCGGTGTGGGTCACAGGGCTCTCCTGATCCTCTGCTCTTCCTGCTACC
CCCCTCCCCGTAGGGGCGGTGGGGGGATGTTGTCTTTGTGCACAGCTTGCAGCCGAACTCAGGGCAGCTTTCAGTTGCTG
CTGGGCTGGCCCACCGGGTGCCCAGGATTCAGTTGCTGGTCTGTCCGAGTCAGGGACTTTGCAGGCAGGCATGGGGGTGG
GGCCCGTCTGGGTCCTGACTGTGCTGGAGCATGTAGAAACCCCTCCTGGGCGCCCCACCTGCTGTTTCTGCGGCCCCTGA
TAAACGTGTGGTGGGCACTGCGCGCTCAGGCGTGCTACTCTCGGTCCCAAGGGTGACTGGGAGGGCGTCCCACAGCAAGC
AAGCAGCTCTGACCCTGTGTGCTGGCCGGGCTCGTGTTCCAGGCCATGGCATGTCCGAACGAGGTGGTGTCCTATGAGAT
CGTCCTGTCCATCACCAGGCTCATCAAGAAGTATAGGAAGGAGCTCCAGGTGGTGGCGTGGGACATTCTGCTGAACATCA
TCGAACGGCTCCTTCAGCAGCTCCAGGTGGGGTGGGGGCAGGAGCTCCGGGGAGCACCGGGAACCCAGACAGGCAGGCTC
GGCCCACTCAGAAGATGGTACCTTGGGCCCCATCTCTGGGGGTCCCGCAGAGACTGCCAGAACCGTGTTCTCTGGTGATT
CGCAGTGGCGCTCATCCACCTTCCACCGGAGACAGGTCTGATTTTTCCAGACGTGGTGCATCGTTTAGGCCCCAGACAGG
AATATGCAGTAGGTGAGCCGGGGCTGGGCCAGTGCTGTCCACAGTCCGCAGAGTGACCTGCAGGCCGCCTTCGTGGCCTG
AGTGGGCCCCGGCACAGTTCCCAGAGGGATGCCAGTGTGGCTTCCGCATGACTTTGGAGGACCGCATTAGTCGAGTCTGT
TAACCACAGCTTTAAGGAGGACTCCACGGCCACACGGGCTCATCAGCATAGGGGCCCTGGGGAGGCGAGGCTAGTATCCA
GCAGCCTCAGGGCTGTGCCTTTTCCTGGAGCCTGGGGCGGGTGATGTACAGGAGGCCAGGCAGCAGAAGGGAGGCCGGGA
CTTCGCCGGGACTTAGCAGGGACTGAAGTCCTCTCAGAGCCTGTCGCTGGGCCAGAGCATTGCCCCCGACCGCTGGTGGC
AGTGGCAGAGGTCATAGCCTGGGGCTTCTAAAAGAGGCTGGACCTGGGAGAGGCAAGAAAGGCTTGTAGTTGTGGCTACT
CTTGGCCCTCCTGCCCGAGCTTCCTTCTTGGCCCAGCTGCATGGGCACAGCCAAGATTCCTTGGGGGGTGGGGTACGGGC
AGGAACAGCAGCTGCCATCACAGCCACTGTGGCCCCTTGAGAGGATCTGGGGGGTGTCCTGGGCCACGTGGGTCAGGGTG
GCCCCTGGAGAGGATCTGGGGGTGTCTCAACCCATGAGGCCCGGAGCGGCCTCAGAGGGCTGGGGGCGTCTGTCCCCATG
CGGCCCAGAGCGGCCTGAGAGGGCTGAGGGTGTCTCCATGCGGTGGGTGTGTAGCGAGGCCTCTGGTGCCAAGTCCATGT
GGGGAGTGGAAGTCAGCCTGTGTCATCGTGCCTGGTACTGCAGACCTTGGACAGCCCGGAGCTCAGGACCATCGTCCATG
ACCTGTTGACCACGGTGGAGGAGCTGTGTGACCAGAACGAGTTCCACGGGTCTCAGGAGAGATACTTTGAACTGGTGGAG
AGATGTGCGGACCAGAGGCCTGTGAGACCCCCTCCTGGGTGGGGCCTTTGGGCTTTGGCTGGTGGGGAGGGGCCGGGTGC
TGGGTGAAGTGCAGCTTTCTGAGCCTCAGAAGCCAAGGGCCAGGTGGGCGCCTGCTTTCCAGGTTTCTGCACTCGGCAGG
GAAGGCTGGCAGGCACAGCACGTGTTTGGTAACAAGCTCGGGGCTAGCCCACCCATCAGTTTCCTCCCACCTGTGTGGAG
CAAGCTTCCATCCGGCTCTGTAGAGTCCTGTGGCTCCCAGGCGGCCGCAGTCATTTTGCCAGGAACACTCAGCTTAGGGC
CCAGGCTTTTCCATGGGTTTGGACACAAGTCTTCCCCGCTGCCAGGAGTGCCTTTGTGTCTGGGCTGTGGGCTGCAGGCT
GTGAGGCGGCTGGGCTCTGACAGCAAACCAGCCTCTCGACCAGCAGCCCAGTGTGGAGAAGGAGAGCGCCGGAGGGGCAG
AGGGGCAACACCGGCTCTTCTTTTGACAGGAGTCCTCCCTCCTGAACCTGATCTCCTATAGAGCGCAGTCCATCCACCCG
GCCAAGGACGGCTGGATTCAGAACCTGCAGGCGCTGATGGAGAGATTCTTCAGGTAGGGGGTCCTCTGTAGCCTTGCCTG
GCACCTGGAGCCTGGCCCTGTCTCTGTCTGGGGCCCACCCGGGCTGGGTCTCAGGATGCCCGATGAGCAGGGCCCTCCCC
TCTGCCTCTGGAGAGCCCTGGCTCTGGGTGAGCAGGTGCTAGCTTGCTTTCCAGTCCAGCAGGACAGGTCCTCTCATGAC
GCCACTGGGCTCCCTCTTTTCGGGGGTCGTCTGGAGAGATGCTCCCTGGGAAGCAGAGCTCTGTGCCCTGTGTGCCTGGC
CGCGGGAGGACCCAGAGTCGGGCTGGCCTGCGCCAGGCAGACGGGCTGGTGTGGGGCTGTGGCCGGGCACTCCCCACCCG
CCCCAGCAGGCTGCCGTCCCGCAGGAGCGAGTCCCGAGGCGCCGTGCGCATCAAGGTGCTGGACGTGCTGTCCTTTGTGC
TGCTCATCAACAGGCAGTTCTATGAGGTGCGTGTCCAGGCGGCCGCAGCTGGGGGCTCAGGGCTATTTCTCCGTGGGCGG
GCTGTCTCTGTTGTGCACGTGCTCCCGCAGAGCCGGGCTCTGCCTGGGACTTCGGTCCTGCCGGACCCTCTGCAGCCCCC
AGCGTGGTCTGTTTACCCCTGTTCATTCACTGGCTTGCTCGTCCTGGGTGCCTCTGCCAGGCCTTGACACGTGGCCAAGT
AGCAAGGAAGGCACAGTGCCTGCCCTCAGGGAGCTCCGGCCGGTTTTCACCCAACACAGGAGCCTCTTAAAAATTCTGTG
TGAGTTCGTTTCAGCCAGTCTTGCATGGGGACATTGTCTTCCGTTTCAGTCCTGACGTTCACCCTGTGCACCTGCGTGAT
CGCCAGCCCTGCCTGGTCTCTCCTCTGCGGGCTCTCCCTCTCCACTCCCTCCTCTGGGAGCTCTGTGGCCCCAGGCCCAC
CTTCCTTGAGAGACATTTGTGTGCCTGCCAGTCATACCCCTTTCCCAGGAGGCGCAGCTTAGGCTCTGAGGCTGTCCCTT
CCCACCGAACTCCTCCCTGCAGCCTCGCAGTCCTGCCCTCCTGAGAGCTGCCCACTCTGCTCCTCTCCCCAGCGTCCACT
GTCCTTGAATTGCCCTTTGCTGGGCATTGCGATCCCGCATTCTGTCTGAGGGAGCTAAGGGCCTCCTGGAAGTTCCTCTG
GGTCCTCTGGCTTCTCCCATCAGGGCTGGTCTTGTCCTGGTCTCTGTTCCTGTGGAACTTTTTACCTGCTTCTGTGAAAA
CTCACGCTGTCCTCAGCACAGCACGCACACACACGCATATTCACGCATGCACAGGCACACACGTGCACATGCCCACGCGT
GCACACAGCCACACACACCCTCACGCACACACGCACAGCACCATGTGGGAGGGGTTCTCGGCTGTGACAGTGAAGGGCAG
GGCCTCACCTCGGCTGCTCCTTGTGAGTTGTGGGCCCCGTGTCTGTGCCCGGCCGCCCTGCGGTGCTCACCAGCCTTCTG
AACGAGGAGCTGGACAGGATCCCTGGAAGGGGCCCCGGGGTCTCTGAGTCGCGCTCAGCGGGTGCTTGTGCTCTCTGCCC
AGCTGTGCTGAAGTCCCGAGGGACATGTCCGCTGCTTGCGGGTCGGTTCCTGAGGAATTGGAAGTGTCACGAGATGTGGC
CCTCGTTGGGCTGGCGCTCATTGGCCTCCCTTGTGCCTGTGCAGGAGGAGCTGATTAACTCAGTGGTCATCTCGCAGCTC
TCCCACATCCCCGAGGATAAAGACCACCAGGTCCGAAAGCTGGCCACCCAGTTGCTGGTGGACCTGGCAGAGGGCTGCCA
CACACACCACTTCAACAGCCTGCTGGACATCATCGAGAAGGTGAGAGCCGTTGTACCCGGGGCCGGGTGCTAGCGTGCCA
GAGCTCCGTGGGCAGCAATGGCCTCTGGGCCCTCTGTCCTCCTCTTCGAGTGACCGGATGGCTGTGTCCGTAGGTGAGGC
TCCCCTCCCTGCAGGGTGGGTGTCCCGAGGCCTGTGCAGGGCCTGCCACTGCTGGATTTGTGTCCTGACTGAAAGTCCTG
GACATGGGTGTCCTGTCACACTCTGGGACAGCTGGGCTGGGCCTCCTGGACCGACGCTGGAGCCCAGACCTGGGGCTGGG
GCTTTGGCCTGCCGTCCTCCCTGCCCAGCCAACAGCTTTGCTCTTTGATTTTCAGATGCATTTTGGTTTCTGCACAGTCA
CTCGGGTATAAAGGGCATCTTTGCTTTTGAGCAATAAAGATGAAGGCCGGGCACAGTGGCTCACGCCTGTAATCCCAGCA
TTTTGGGAGGCTGAGGCAGGTGGATTGCTTGAGTTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAATCCTGTCTC
TACTAAAAATATAAAAATTAGCTGCACGTGGTGGCGGGCACCTGCAATCCCAGCTGCTCAGGAGGCTGAGGCAGGAGAAT
CGCTTGAACCTAGGAGGTGAAGGTTGCAGTGAGCCAAGATTCTGCCACTGCACTCCAGCCTGGACGACAGAGCAAGACTC
TGTCTCAAAAAGAAAAAAAAAAAGGGCCGGGCACGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAGG
CGGATCATGAGGTCAGGAGATCAAGACCATCCTGGCTAACACGGTGAAACCCCATCTCTACTAAAAATACAAAAAATTAG
CTGGGCGTGGTGGCGGGCGCCTGTAGTCCTAGCTACTGGGGAGGCTGAGGCAGGAGAATGGCGTGAACCTGGGAGGCGGA
GCTTGTAGTGAGCTGAGATTGTGCCACCGCACTCCAGCCTGGGCGACAGAGCAAGACTCGATCTCAAAAAAAAAAAAAAA
AAAAAAAAAGGTGTTTGTGGTAGAAAGTGTTCTCACGGCTGCTGACTCAGAACCATGAGCCTGTGTGTAAGTCCTGGCCT
TCTCTTCAAAGGTGATGGCCCGCTCCCTCTCCCCACCCCCGGAGCTGGAAGAAAGGGATGTGGCCGCATACTCGGCCTCC
TTGGAGGATGTGAAGACAGCCGTCCTGGGGCTTCTGGTCATCCTTCAGGTGGGTGTTCTGCACGAGGCCTCTGCTCCCGG
GGCGCGCATGGCTAGCGTCCACCAGCTGCATCTGCGTTGTGTTGGAGTCTGTTCCCCAGCGGGACCCACACCCTCCCTGG
ATTTGCTGAGGGTGCGGTGGTCTCAGCAGGCAGCAGAACCTTCCTCCTGCTCTTGTGGAGGGATGGATGCAAGAGGCCCC
GTTGTACGCCCTGACCAGAGCTTGTCTCTGTGCTCCTGAGTCAGGGCCGGAACCATGTACCATCCTCAGCGTGGCGCTTG
CCCTCGTCACCCAGCACAGCACCTGGGAAGTAAGGGTGGCCCTCCATTCCTGCCCTGCAGTCCGTTTAATATTTGCAGCT
GTTTTGTTGAGATTTAATTTACATATCATGCAATTTACCCATTCACAGTGAACAGTTCAGTGGTTTTCAGTAAATTCACA
GAGCTCTGCAGCCAACCCCACAGTCAGCTTGAGAACCTCCTGAGCATACCAGTAGCACACGCTCCCATCCCCCGTTGCTC
CCGTACCCCCGGGTACCATCAAGCTGCTTCCTGTCTCTGTGGATTTACCTACTCTCAACATTTCATGGAAGTGGAATCAC
ACAAAATTCATCCATAAGATGTTGGATGGTAGAACAGTTTCCTGTCTGCTGACTGGATTGTTCCACCCAGCGCCATGTGT
CCAGGCCCGTCCAGGCTGTGGCAGCTGTTGGTGCTCCCCTCCTTTTCATGGCTGAGTAGTATTCCATCATCTGGAAGGAG
CACATTTTGTCTGTCCGTTCCTCCATTGGTGGACATTTGGCCTGTGTCCGCCTTGCAGCTGCGGTGAGTGGTGCTGCTGT
GAACCTTCTCCTACGAGGGCTCCGCCGGGCCTGCATTTTCACTTTTGGGTCTGCACCTAGGAGTGAATTGTTGGGCCCTA
GGTTTAGTCTGCATTTGGTGTTTCAAGGCGATACCAGGCTGTTTTCCACTGGTGCTGTGCCATTTTCCATCCACTCGAGC
AGCATGTAAGGGTTCTGATTTATCTTTTTTTTTTTTTTTTTTTTTTTTGATACAGTCTCACTCTGTCGCCCAGGCTGGAG
TGGAGTGCAGTGGCGCGATCTTGGCTCACTGCAACCTTCGCCTCTTGGGTTCAGGCGATTCTCCTACCTCAGCCTCCTGA
GCATCTCGTATTACAGGCACCTGCCAACATACTCGGCTAATTTTTTGTATTATTAGTAGAAACTGGGTTTCACCATGTTG
GCCAGGCTGGTCTTGAACTCCTGACCTCAGGTGATCCTCCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGC
CACCACGCCCGGCCTGCCTCTACTTTTCAAAGCCTCACAGCATCACTTACGTGTGACTGTCAGTGTCAGTATCGTGTAAA
ATATAATGTATGAATCAGTTTGCTCAAAAGCTCATCCTTAAGATGTTGGATGGTAGAACAATTTCCTGTCATGTTTATAT
GTCATGGGTTTTTATTTCTTGCCATGGAAGTTGAAAGTGGTGATGATTTTTTTTTTTAATTAATTTTTTGAGACAAGATC
TCACTCTGTCGCCCAGGCTGGGGTGCAGTGCTGTGACCATAGCTCAGTGCAGCCTTGAACTCCTGTGACCAAGTGATCGT
CCTGCCTCGGAGGCCTCCCAAGTAGCTGGGACCATAGGCACACGTCACCACACCTGGCTAATTTTTTCATTTTTTGTAGA
GATGGGGTCTTTATATGTTGCCCAGCCTGGCATCAACCTCCTGGCCTCAAGCAGTTCTCCCACCATAGCCTCCCAAAGTG
CTGGGATTACAGGCATGAGCCACCACACCTGGCCGTGGTGTTTGATTAAAAACCAGGCATCAGCCGGGTGTGGTGGCTCA
TGCCCGTAATCCCAGCACTTTGGGAGGCTGAGGTGGGTGGATCACCTGAGGTTGGGAGTTCAAGACCAGCCTGACCAACA
TGGAGAAACCCCGTCTCTACTAAAAATACAAAATTAGCCGGGCGTGGTGGCGCATGCCTGTAGTCCCAGCTACTCGGGAG
GCTGAGGCAGGAGAATCACTTGAACCCATGAGGCAGAGGGTACAGTAAGCCCAGATCACGCCATTGCACTCCAGCCTAGG
CAACAAGAATGAAACAACGTCTCAAAAACAAAACAAAGCAAAAACAGGCATCACCTCCTTGGTGTCTCATCCACATGAGC
ACCATGCTCTTTACTGACTGGTTGGGAAGGGGTGTGCTGGGCTGTGGGGGCCTATGGCCTGGGAGAACTGAGAACCTTTC
TGCTTCTGCAGAGGGAAGGAAAGAGGTTCTGTTGCCCTTACTTGGAACTCCAGCCCTGGAGGCCTGAGGGTCTGGGCTGC
AGAACTGAGATATTTCCTAGTTGAGGCAGAGTCCTGGTTCTGGCTGCTTTCATTTCTTTATTTTTTTGAGATAGAGTCTC
ACCACTATGTCACCCAGGCTGGAGTGCAGCGGCACGATCTCACCTCACTGCAACCTCCGCCTCCCAGGTTCAAGCAATTC
TCTTGCCTCAGCCTCCTGAGTAGCTGAGATGACAGGTGCGCACCACCACACCTGGCTAATTTTTGTATTTTTAGTAGTGA
CATGGTTTCACCATGTTGGCCAGGCTGGTCTCAATCTCCTGACCTCAAGTGATCCACCCACCCCAGACCCCCAAAGTGTT
GGGATTACAGGCGTGAGCCATCGTGCCTGGCCTGTTTTCATTTCTTTTGTTATAATTGAAAAGTAACACAGTTGACTCTT
GAACAGTATGGGGCTGGGAGTGCCAGCCCCTGTGCAGGTGAAAATCCCCATCTAACTTTTAACTCCCCAGAAACTTTACC
AACAGCCCTCTGTTGACTAGAAGCCTTGCTGATAGCAGACAGTCTATTAATGTACAGCTCGTGTGTTTTATGTATTCTGT
GTTTTTACAGTGAAGTAAGCTAGAGAAAAGCAAATGCTGTTAAGATGCTAGGCATGGTGACTCACGCCTGTAATCCTGGC
AGTTTGGGAGGCCGAGGCGGGCAGATCATGAGGCCAGGAGTTCGAGACCAGCCTGACCAACATGGTGAAACCCCGTCTCT
ACTAAAAATACAAAAATTAGCTGGATGCGGTGGTGCGCACCTGTAATCCCAGCTACTCGGGAGGCTGAGGTAGGAGAATC
ACTTGAACCTGGGAGGTGGAGGTTGCAGTGACCTGAGATCGTGCCATAGCACTCCAGCCTGGGCGACAGAGAAAGACTCC
GTCTCAAAAAAAAAAAAAAAAAAAAATCATAAGGAAGCGAAAATACATTTCCTGTTCCTTAAGTGGAAGTGGCTCATCAC
CAAGGTCTTCATTGTTGTCATCCTCATGTTGAGGGGACTGAGGAGGAAGGAGAGGAGACACATGGTCTTGCTCTCTCGGG
TGGGAGAGGCGGAAGAAAATTGGCATGTAAGTGACCCATGAAGGCCAGCCTCGTGCTGTTCGAGGGTCAGAGAGTTTGCA
CAATGGACACGGTGACAAGTTTGATTCCCCTTTTCCTGCCTGCCTAGTGGGCCCGGCAGGGCGGCAGCTGCTGTTGGTTC
CATGTGGCCTTCCCAGAATGGGGGGTGCCAGGCACTGTGTGAACCCCCACCTCCACCTCTTTTTTGTCCGAGGAAGGGAT
GTTGCTTTTATGTCATAATATTTTGAGATGAGGAGAAACTGTTAATCATTTAATCATCTTTTTTTTTGAGATGGAGTCTC
GCTCTGTCGCCCCAGCTGGAGTGCAGTGGCGCAATCTTGGTTCACTGCAACCTCCGCCTCCTGGGTTCAAGCGATTCTCC
TGCCTCAGTCTCCTGAGTAGCTGGGATTTACAGGCATGCACCACCACACCTGGCTAATTTTTTTTTTTTTTTGAGACAGT
CTTGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCACGATCTCGGCTCACTGCAAGCTCTGCCTCCTGGGTTCACGCCATTC
TCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGTGCCCACCACCACGCCCGGCTAATTTTTTTGTGTTTTTAGTAGA
GACAGGGTTTCACCATGTTAGCCAGGATGGTCTTGATCTCCTGACCTCATGATCCACCCGCCTCGGCTTCCCAAAGTGCT
GGGATTACAGGCGTGAGCCACTGTGCCCGGCCTAATTTTGTATTTTTAGTAGAGATGGGCTTTCTCCATGTAGGTCAGGC
TGGTCTTGAACTCCTAACTTCGTGATCCACCCACTTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCACACC
TGGCCTCAGTCATTTCTTTCAATGATTTTTTAATCATTTAAAGGTGTTAATCATTTCTTTAAAAGAATAACAGTGTAACC
ACTTACCTCCAGAGTGCTGCAAAGGGTCCCTCAGGCCAGATTTCCCCTGGCTCCTGCTGGCCTCGGCCCCAGGGTTGCTG
GAGGCAACAGATGCTCTTCACACCTTGCCACACGTGTCTGGGAGGTGCCCTTGACCTTTTGGGAGGGGCTGCCTACACCT
GGGATCGCCCTGCAGCACACACTCCCCGCCCCATTCTGCCCTGTCTGCCACGCAGCTGGAGCTTCTCCATTGAATGGACT
CTTCCTCACCTGTTGATGACTGCCCTGATGATGAGATGGGCACGAGGTTGGGTTTTACTTTTTGCTGCTGTGGAGAGAGA
GTCCTGGTGGTCCTGGGTTTGAAGGTCGTGTGTTTTGAAGCACGCACTCTAGAGCAGCCGCCCCGGCCCCTGCTCCGGGA
CAAGGGTGCTGTCTTAGGACTGCGTTTTCACCTCCTGCGCCGTGGTGAGCTGCGTCCTCTCTCTGCAGACCAAGCTGTAC
ACCCTGCCTGCAAGCCACGCCACGCGTGTGTATGAGATGCTGGTCAGCCACATTCAGCTCCACTACAAGCACAGCTACAC
CCTGCCAATCGCGAGCAGCATCCGGCTGCAGGTATGGTGGCTGGGGTTGCGCAGCCAGTTCCTGGGGGCCCAGCCAGGTA
TCCCCGTCTCGGCAGGTGTGGTTCCTGGAAGCTGCAGAGACGGCCCCAGGATGGGGCCTCAGCTGACCGTCCCTCCTCTG
CACCCACTGTGGCCGCAGCCTCCCCAGTCCTGGTGTCCTTCCCTCTGCCTGCAGTCCACACATCTGTGGCTTGTCGCTCT
AAGCCGCACGGTGACATGGGTTGGGGCAGAGAAAAGGACGCACGGCGACTTCCGGGGCAGTGCATGGCCCTGACGCTCCT
GGTGCTGCAGAATCTGTGAAGGACCTGCAGCAGAGGGCTGGGCAGGTGGGCGGCACAGGGCAGAGCTGAGAGGGCAGAGC
TGAGACGGCAGGGCAGGGCTGGAGAGGGCAGAGCTGAGAGGGCAGGGCAGGGATGGGCAGAACAGGGCTGGAGGAGTTTC
GCTGAGTTTGCGCTATAGATGTTGGCACCAGGCTGAGCAGAGGTGACTGGGATGGGAGCCCTCCCTCCTAGAGCAGGTGC
TCTCTGGGGCCACCCCTGTGGCCTCAGAGTCCTGTTCAGCCTGTCGATGGAAGAAGTGGCAGGGCTGGGAGCTGAGCTCC
GCTTTCTGGCAGTTGGGGGCGTGTGGTGCTGCCAGAGGAGCGAGGCGCCCATCCCTTCCATCCCAGGCGGGCCCAGCTGT
GGTGGTGGGGACACCAGGCTCTGTGAGCTCCGAGGCAAGGGAGGGAGGAGGCTGTGGGTGCTGGGCCTCCGGTGTCACCA
GGACAGAGCCTGTGTCTGTGTTGGGATGTGGGTGTGTGCACATCAGCAGGTGGCCTTTTCTGAGTGCCTGTGGTGCTGGA
CGTGGGTCTGAGCAGGTGGGACGCCGCCTGTCCTGGGCCTGCACGAGCTTGGCTCTGGCTTTCACCATCCTCTTCCTGAC
AGGCCTTTGACTTCCTGTTGCTGCTGCGGGCCGACTCACTGCACCGCCTGGGCCTGCCCAACAAGGATGGAGTCGTGCGG
TTCAGCCCCTACTGCGTCTGCGACTACATGTACGCGGGACCTCGCCCACGGCCCATGAGGCTCAGGGCGTCAGAGGCGCT
GGGGCTGTGGTGGCGCTGTTTGCATGTCTGAGGGATGTCCCAGGGTTGGGAAGAGCCAAGTCTGTTCCGTTCCTGCTGCG
GGGACTTGGCCTCAGCTGCTTCTCTTGCTTCTGCAGGGAGCCAGAGAGAGGCTCTGAGAAGAAGACCAGCGGCCCCCTTT
CTCCTCCCACAGGGCCTCCTGGCCCGGCGCCTGCAGGCCCCGCCGTGCGGCTGGGGTCCGTGCCCTACTCCCTGCTCTTC
CGCGTCCTGCTGCAGTGCTTGAAGCAGGTGAGTGGGGCCGGGCAGGGACCATCCGTCCCACGTTGGGCCAGGAGGACAGG
GAGCTGCCACCTGCCTGCTGGGCCTCCCTCCCTGTCTGGCCTGTGGAGGGCAGCCCTCCCTCAGAGCTGAGCCTTCCCCC
TTCCCCGAGCAGCTGCAGGGACAGAGGCCTGCGCTGGGCAGGCTCCCCCGGCTGAGAACAGGGCTCCATAGCCCTTGACG
CTGTGCAGCCACAAAGCAGAGCCTCAGATGCTAGCTTCCGCCTCTGTCTCTAGGGTCCAGAAGGCCCTGTCCTGACGCCT
CCTCTCCTCGCAGGAGTCTGACTGGAAGGTGCTGAAGCTGGTTCTGGGCAGGCTGCCTGAGTCCCTGCGCTATAAAGTGC
TCATCTTTACTTCCCCTTGCAGTGTGGACCAGCTGTGCTCTGCTCTCTGCTCCATGGTACCATGGCCGGCCTGGGGTTGG
GGTGGGGGACCCAGTAGGGTTTTTCCCCAAAAGACTGCGAGCCTCTGGGCAGAGCGAGTGAGACCCTTCGGGCTCGGGCT
CCATTTCCCTCAAACTCAGCTGCACTCTGGAGCGCAGATTGTGCCTTGGGCAGGGTGGAGGGACCCCTGCCCCAGCTCGC
AGCTTTTGGGACTGACGTCAGAGGTCCCCAGCCAAGGGCATGTCACTGAATGTGGATGTCTCCCATCTGTGCTTTTCCTA
AGTGGGGCTCCCGTGCCGTTCACCTCACATTCCTGGTGTGTTACTTGGCAGGCACTCCCACCACTCCGAAAGGGAGGCCC
TTCCTGGGAGGGAGGCAAGAAGGCTCCCCAGCCCCTTTGCCCCCTTTCCTGGGCCTGCGTTCCCAGGGCCTCCCCAGCCC
CTCTGGCTACCCCGTGACCTGGCCGCTGGGGAGAGGTTTCATGCCTGGATTTGGTCATCAGCTTTCAGGCCCAAAGACAC
TGGAGCGGCTCCGAGGCGCCCCAGAAGGCTTCTCCAGAACTGACTTGCACCTGGCCGTGGTTCCAGTGCTGACAGCATTA
ATCTCTTACCATAACTACCTGGACAAAACCAAACAGGTAGGAGGTCAGAGCAGGACAGGCGAGCTTGATGGGGCCTGGGA
TTCGAGGGCCTGGCCCAGGTAGGCCCCACATTTTTCTCATAAACGAGTTTCTGCCAGGCCAGGGATGAGTGAGTTGGCTC
TGCTTCCCTGGGTGGCTGCCAGATGCCCAGAGTGGGGACATCCGATTCCCTGGTGCTTCTAGCTCTCTTTGGGGCCTGGG
AGCCATCCAGTGTTCCCTGTCCACCCCGGACAGCATCTCTGCTCTCTGTAGAGCGTTGCCTGGCTTGTTCCTGCTGTCCC
AAGGGGGAGGTGGCCATGCCGGTTGGTGGAGCTGGGCTGGTTCTGAGGCGCAGGGTGGGCAGGCCAGAGAGTCTGGCTTC
TGCCTCCCTCCACGCCCCATCAGGTGCCGGAAACTGTCCCTTCACCTGCGATCTGCCTCGCCCCCGTCCCAGTCGCATTC
TTCCACACCTCTCTTTGACATGGCCCTCCGGGACGAGGAGCTGGTGTCCTAGAGATTCTGGCCTCCGCTCAGGGCCATGC
CCGCCAGGAGATGCTGACTCTGAGGCTTGGCCCATCTGTGCCCCGGGCCTCAGCTTCTGATGGTGGCCCTGTAGGGAGCT
GTTGTTGGGTTCCCATCCCTCAGGCTCAGCCCCACCCTGTTGGGCCCCTTCAGCCCCTCTGAGAGGCTCACTGGGTCCTC
ATGGGTCTTGCCTCAAAGCATAGCCAGCCTTGCTGGGCTGCAGGTTCTGAGGCCTTACTGGCCCACAGTGTATCCGAGGG
GTGAGGCCGGCTTTGGGAAATGGAAGCTGTTCCCGGGACACTGCCTGGCAGGCCATCTGGCCCCGGGCTCTGCCTGAGCT
CCGCTCATCTTCTGCTGTCCTCATGGAAGACACTGCCCAGGGTTGGTGTGGGATCTGGTGGCTTGGCCACTTCAGGCAGC
ACTGCCCCTTGCAACAGAGCCAGCCTGTGAAGGGCCCAGAACCAGGGGATGAGAGCCCAGCATGTCTGGGTTCTGTTGGC
CTGTGGGATCGTGTCGGAATGCAACTGACCGGAGCAGTCTGCTGTGCAGAGTCTGCTCGGGTAGCTCAGCACTGCTGGCT
CTGCCCCACAGGCATTCAGGGACTTGCTAAGCCTCGGCTGTTCTCCCGGTGGAGCACTCGAGGTTGGCGAGGGGTAGGCG
AGGCTGCCTCTGCTGCAAGCGGGTGGGGCCTGAGGTGTCCTGTCTCCTGCAGCGCGAGATGGTCTACTGCCTGGAGCAGG
GCCTCATCCACCGCTGTGCCAGCCAGTGCGTCGTGGCCTTGTCCATCTGCAGCGTGGAGATGCCTGACATCATCATCAAG
GCGCTGCCTGTTCTGGTGGTGAAGCTCACGCACATCTCAGCCACAGCCAGCATGGCCGTCCCACTGCTGGAGTTCCTGTC
CAGTGAGTCCCCGCCCTGCCTGCGCATGCACCCGAGAGGTTCGGGCTGTGTAACCTGTGCGGGCTTCTCTGGTGCCCTCT
CTCAGGACTCCTTGGGGAACCTGGGTGTCTCGCCTTCTGCTGCCTCAGGGCCTGGGCGTCTCTGCCCGGCTGCCATGAGT
GCTCTCCTTCCTGGCTTTGAGGGGCGGCTCCTCTCACCCCTCTAGTGTCCATGTGAACGCTCCTCCTTGAAGAAGCCTCT
TCCCCCCCGAGCAGTGGCCCTCCCCTGGTTTTGGGCCTCCTCTCTGTCCAACAGAGCACACGCCGCTTCAGGGGGGCTTT
GTTCGCTTCCCCCAGACTGTGACTTCAGGAGCTCAGGTGCCTGTCCCTTCCCCTCACCGCCTGTGCGCATCTGGGCAGGC
CCTCAATGTTGAGATGGCAGAAGGGCACTGCTGGGCCCGCACTTGGTGTAGAGGCTGGAGAGAAGATCGTGTGTGCTTTG
TGGGCCACATGCAGGTCCTGTCGGTCTTTCTGTTTTGTTGATAACCCTTTAGAAGTGTAGAAGCCTGGCCAGGCGCGGTG
GCTCAGGCCTGTCATCCCAGCACTGTGGGAGGCCGAGGCGGGTGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGGC
CAACCTGGCGAAACCCTGTCTCTACTAAGAATACAAAAATTAGCCGGGTGTGGTGGCGGGTGCCTGTAGTCCCAGCTACT
CAGGAGGCTAAGGCAGGAGGCAGGAGAATCTCATGAACCCAGGAGGTGGAGCTTCTAGTGAGCTGAGATCACGCCACCGC
ACTCCAGCCTGGGCAACAGAGCGAGACACCGTCTCAAAAAAAAAAAAGAGAGAAGTGAGGCCGGGCACGGTGGCTCACGC
CTGTAATCCCAGCACTTTCGGAGGCCGAGGCAGGCGGATCATGAGGTCAGGAGATCGAGACCATCTGGCGAACACGGTGA
AACCCCGTCTCTAATAAAAATACAAAAAAACTAGCCAGGCGTGGTGGCGGGCGCCTGTAGTCCCAGCTACTTGGGAGGCT
GAGGCAGGAGAATGGCGTGAACCCAGGGGGTGGAGCTTGCAGTGAGCCGGGATCGCGCCACTGCACTCCAGCCTGGGCGA
CAGAGCCAGACTCATCTCAAAAAAAAAAAAAAAAAAAAAAAAAGAGGTGCGGAAGCCTTTCCTCACGGATCACACAAATG
GTAGGCGACAGCTCGAATTGGCCCAGAAGCTGTGGTTGGCTGGCCATGGGACCGAGAGTTGAGGCCAGGGTCGGGAAAGC
CACGTCCGTGTGGCCGTGGCCTTCTCTCCTCTGCAGCACCCCATCGCTGCCGTGGGCAGAGCAGCCGTGTTGGCCTTCAG
AGGCGCTGCACGGGACCCCGGCTCCCCTGACCACCCTCTCCATTACCGCAGCTCTGGCCAGGCTGCCGCACCTCTACAGG
AACTTTGCCGCGGAGCAGTATGCCAGTGTGTTCGCCATCTCCCTGCCGTACACCAACCCCTCCAAGTGAGTGGTCGCCCC
AGGCCCTGTGCCTCCCAGCCGTGGCCCCCGCTAGGCCTTGCGGCAGAAAGCCCCGGCAGCCTTTGTCCCCAAGGCCTGAG
CGCCTCGGTTTTTTGCACTTCATGCCCTGGGGATGTTTCCCTGCTGCCAGGATGGAGTGCCAGCCCCCTTCTCATCTCAG
GTTTAATCAGTACATCGTGTGTCTGGCCCATCACGTCATAGCCATGTGGTTCATCAGGTGCCGCCTGCCCTTCCGGAAGG
ATTTTGTCCCTTTCATCACTAAGGTGGGCTCAGGGCCGGTGAAGGCTGTGTCTCTCGGTAGGCCAGGGCTTGCTTTGCCC
TTGGCTGTCCATGGTCGGGCAGAGTGACAGGCAGGTGGAGGGCAGTGGGAGGGTGTTTGGGGCTGTGCCTGTGGCGCTGG
GGGCTCTGCTGGGCAGCCTGCAGGGCTTTGATGCGCGGCAGGCATTGAGGGGTGGGAGCTGGGTGCCGCCGCCTTGCCCC
TAGCCTGCAGCTTGTCCCTGGCCAGGGGGCACCCGGCAGGCCTGGTGAGGGCCTCCAGCCCCCATTGCCACCCCTCACTG
TCTGGGTGTGCTCACTCTGCCAGGGCCTGCGGTCCAATGTCCTCTTGTCTTTTGATGACACCCCCGAGAAGGACAGCTTC
AGGGCCCGGAGTACTAGTCTCAACGAGAGACCCAAGAGGTACGGCCTGCGGGGGTGTGCCTGGAGTCGGTGTGGGGTGGG
GAAGGACATGGGGCTGTGGCCTGCCTGACGGTGCCTCCAAGTCAGTGAGTGGAAATGGGTCCTGTGTGCCCTGGAGTATG
TGAGGCAGGGCAGGACCTGCAAGGGCCGCTAACACCCCTCAGCCCCTCAGCAGGTTGGCCGTGGTGGCCTGGGTCCGGGC
TGCGTGTGCCACGGGCACCTACTTGTGGAATTGGGGGTTGGGGTGCAAGCTTTAGGCGCCTGAGCCCCTCGAAGGAGCCG
GCCTTGTCTGGGGCTGCCCCCTCCTCTGCAGCCCCCAGCCTGCTGCTAGCCGGGGACTCTGCTTCATCACCGCCGCCTTG
CCGGACCGCAAAGAGCTGAGCCAGCCTCTGTGTTCTTGTTTGCATTTCATTTGAACGGCTTTCTCCTCCTGTCCCCCACC
TTCCTGCCCGAGCTATTTTGGCTTTCCCTAGATGGGAATACGGCATTTTCCAGCGTGACCTCAACTCGGAAGCTGTTGTC
TCCAGCCCCTGGGGGCCGGGGGCCAAGCTCGGCCATTACGGCCAGAGACTACTTTCTGGGGTCTTGGTCTCTTTTCCTAG
TGACCTTCAGGGCCTGGCCACTGAGGCCTCAGTGCCGCCTCGGTCAGAGCTGGGCGGTGCCTGCCTTCCGCGGGTGGGTG
GGATTGCCTGGCCAGCACAGCCTGGAATCTGCCGTGGGGGTGACCCACACACGTTTAATTTGCACTGACGTTGTTTGTTT
TGGTGTCATGCGTGAAGCCTTACTTGTTCTCAGTCATGTTTACCAGACGTATTATCATGCATTTTTGTTTTCTGTCTCTT
CCCCGCTAACTGCCCTTTGGCATGGCTCTTTTTGCTCATCTCACCCGCGGGATCTCTCCATCCTGACCCTGTGGCCTGGG
ACCTTTCCTCCTCACCCCTCCACTGGCTTGTTCTCCCCTTCCCGGGAGCTGGGCTCTCTGGGGCGTTGGGGCTCCTTCCT
CACCCGATAGTCTGAGGATAGCCAGACCCCCCAAACAAGGCTTGAATAACTCTCCACCCGTGAAAGAATTCAAGGAGAGC
TCTGCAGCCGAGGCCTTCCGGTGCCGCAGCATCAGTGTGTCTGAACATGTGGTCCGCAGGTAGCGGGACTGTCGGGTGGG
GGGCACGGACCCTGGAGCTTGGCCCCGTGAGCACCTGGGTGGCAGTGCATGGGGCTGCTTGCATGACCTCATCGTCTGCC
CGTGTCCTCCCTGGCCAGCCCAGGGGGAGCCGGTGACGAGGGGTGGAAAGGTTGCATTCTGTCCCCAGGCCCCGTATGAG
CACGGGCTGGTTGCACGCATCCCCAGGCCCCCTCGGGGTGCCGCTCCGAGAGAGCCAGGCGTGCCGGGCAGCAGCCTCCC
CAGGCTGTCCCCAAGGGCCGCAGTGTGGGTTGGGGGAGACACCACTCCTGGTTTTGGCCTTTTCGTATTCTCTAGAATGG
ACGTTTTTCTTCGGGCTTTCTTCTCAACAAGGTTTATTTTTTGTTGTAGCTGAAAGGGAACAAGGGGCATTTGTGGAGGG
TGCTGGGGTGGGGCAGCCTGGGAGGGCCTGGGTGGGGGCTAGGATCCTGCAGGGCATGGGCATGGGCCTGGGCCCCAGGC
CATGGTCTTAGTTCTCCCCGCAGTGTCTGGGTGCAGGTGTGGGCTCTCGGGCTCTCGGCTGTCACCTGCCTGTGGGTCAT
CGCTGCTGGCACTGGCAGAGGGGATACCTGTCTCCTCCTGGAAGCCCGTTGCAGGCCAAGGGGTCCCATGGCCCTCAGTC
CATCCACCTCCTCACCTCAGGCCGGCCTCTGCTGGGTGGGACTTGGCCAGGGGTTGGGGTGGTAGAGGTGCTCGGTGAGG
CTTAAAGCCATTTTCTAGCACATTCTGTATCATGAGCAAAATATTGCCTAGGGGCTATGAAATTTGTATCAGAATGAACT
CCCATAAGCCTCTTCCCTGTCACTGGGTGTGGAGCTCAGGCAGCCGCTCGCCTGCCTGAGGGTGACGGTGGAAGGCCACA
TGGGGATCCCAGACCTCTGTGTGCTTGCCGGAGGCAGCCTGCGGGCAGAATGCAATCTGGGCCTGTCTGTGTGGCCTCCG
CCTCTCTGCATGACTACACCGTTTCGCCAGGAGGCCGTAACCTAGTGCTCCCGTGGGCTTCGGTGAGGGGGATGTCGGTC
TCTAGCCTCCTGAGTCTGCTCCGACCAGTAGGCCTGGTCTTCCCCACCCAGCGTCTCCCCGTTCTCTGGGACAATGTGGT
CCACGTGATTCTCAAGCTGAGGCTCGCTGGGCCGCCCACGCCCTGTTGGGGTCTTTCCGAGCGAGGTCCTCAGCCGTGCA
TGCGTTGAGCTTTGGCCCTTGGTGATAGGTGGCTCGGCCCGCCCTACCTGGCACCCTGACCCTGGTCACGGCCTCTCCCT
CCAGCAGGATACAGACGTCCCTCACCAGTGCCAGCTTGGGGTCTGCAGATGAGAACTCCGTGGCCCAGGCTGACGATAGC
CTGAAAAACCTCCACCTGGAGCTCACGGAAACCTGTCTGGACATGATGGCTCGATACGTCTTCTCCAACTTCACGGCTGT
CCCGAAGAGGTCCAGGCGGCACTACAGGGCTGGGCGGGCCTGCGGGAGCTCCACGGGCAAGCTGGGTTTCACGCTCCCTG
TCTTCTAGGTCTCCTGTGGGCGAGTTCCTCCTAGCGGGTGGCAGGACCAAAACCTGGCTGGTTGGGAACAAGCTTGTCAC
TGTGACGACAAGCGTGGGAACCGGGACCCGGTCGTTACTAGGCCTGGACTCGGGGGAGCTGCAGTCCGGCCCGGAGTCGA
GGTGACTGCACCTTCCTTTCCTCCGCGCCTGCCAGCCTCGACACCGGCTGTCCCGAGCCCAGGCCCACGTGGCACCCTCG
TACCAGCCTGGGGACTAAGTCCACCCTGTGCGTGGGATTCTCTTCTCAGCTCCAGCCCCGGGGTGCATGTGAGACAGACC
AAGGAGGCGCCGGCCAAGCTGGAGTCCCAGGCTGGGCAGCAGGTGTCCCGTGGGGCCCGGGATCGGGTCCGTTCCATGTC
GGGTGAGCCTTGGCCCCAGCCACCTCCACACAGGCACCGGGGCTCCCTCAGTTGCTGCTGGTCCCAGTGTTCAGGAAGGC
CCCGAGCCCAGGGGCCGGGGTGGCTGGCTTCAGGCCCGGCCCACGTCCTGACTCTGGGGTGAGCCTTCCACAGCTCACCC
CAGAGCCGTGGAGTGGTGGAGTGTGGCCCGCTTGCTGCAGAGGGGCCTGCTCTGGGTGCTGGTGTTTCCTGCGGGTTTTC
AGCTCGGCTCAGTCCTGGAGCCCTTCTCTGCTCCAGCGAGCCGTGGTCTGACTGCAGGACAGGTTCTGGGTCCCTCCCTG
TGGCCCTGGGTTCACTGAGGCCAGCACTGTGGTGGGCCGTGCCCCAAGGGCAGAGCTGCCACCGTCTCTGGCTGCCTGTG
GCACTAGCTTGCCAGGCTCGGGGGGAGCATTCAGCTTGAGGCTGGTGGTTTTGCATCAGGTAAGTGGTGGTCACCAGTCC
TCTGCCCTCTTCTTCAGGGGGCCATGGTCTTCGAGTTGGCGCCCTGGACGTGCCGGCCTCCCAGTTCCTGGGCAGTGCCA
CTTCTCCAGGACCACGGACTGCACCAGCCGCGAAACCTGAGAAGGCCTCAGCTGGCACCCGGGTTCCTGTGCAGGAGAAG
ACGAACCTGGCGGCCTATGTGCCCCTGCTGACCCAGGGCTGGGCGGAGATCCTGGTCCGGAGGCCCACAGGTACTGGGCG
GGGCTGGCCTGAGCGCCATCTTTCTGCCAGTCACCCACAGAGCTGTGGACACTCAGGGGCGATTGCAGACTTGGCCCTCT
TGGGATATTTGGGGGTAACTTTTGTTTTTTTTTTGAGACAGAGTCTTGCTCTGTGGCCCACGCTGGAACGCAGTGGCGCA
ATCTCGGCTCACTGCAAGCTCCACCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACCACAGG
CGCCCGCCACCACGCCTGGCCAATTTTTTTGTATTTCTAGTAGAGATGGGGTTTCACTGTGTTAGCCAGGATGGTCTCAA
TCTCCTGACCTCGTGATCCGCCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCAGCCATTT
GGGGGTAACTTGTAAGTCTCCAGAGGTGAGCTGTGAGGGGCGATCCAGGTGGCTGAGGTGGGGCAGGGGCCTGTGGCGAA
CCAAGTGACTTCCATGGCAGAGAGTTGCCCTCCCCGCCTGGAGGCTGCAAGTCCGAGACCAAGGTGCTCCTCGGCAGGAG
GTGCTCCTCAGAGGCCTCAATCCTTGGCATGCAGTTGGTTTTTTCCCTGTGTCCTCACAGGCTCTTTCCTGGATGTCTGC
GTGTTAATCTCCTCTTGGGAGGAAACCGGTCATGGCTTAGGGTCCGCTCTGGTCCCTTGCTAGCCGTAATTAGCTTTCTG
AAACCCAGTCTCCAGAGACAGTCCCGTTCTGAGTTCCTGGGGTTGGGACTAAAGCATACCAACATGGGGGCACAGCTCAG
CCTGTTCCCAGGGGCAGAGGGAGCCCCCGCAGAGGCCCAGAGCCCAGGGACAGAGGGAGGCCTTTGCAGAGGCCCAGAGC
CCAGGGGCGCCTGGGTGTGCCGTGGCTGAGGGGTGCAAAGAGTAGGGGTTCCAGCCCTCGTGGAGGCCTTGGGTCCGGAC
TGTGAGGCTGTGGGCTGGAGGCCGCTGCTCTGAGGTGCCTGGCGGAGCCTGGCCTCGAGGCAGGGGCTGAGCGGGGCAGC
AGGGTGGGTGGCCGTCAGAGCAGCGCTGGCTCCGACATCGTGGTCCTGAGGATTGTGGGAGGGAGCATGAGGGCAAAACC
AGGGCCCAGGCCAGGAGGCCCCTGGGGGGCCAGAGATGGGTAAGGGGAGGTACTGGCCTCAGGCCAAAGGTGCTGCCGCC
TCCGCAGGGAACACCAGCTGGCTGATGAGCCTGGAGAACCCGCTCAGCCCTTTCTCCTCGGACATCAACAACATGCCCCT
GCAGGAGCTGTCTAACGCCCTCATGGCGGCTGAGCGCTTCAAGGAGCACCGGGACACAGCCCTGTACAAGTCACTGTCGG
TGCCGGCAGCCAGCACGGCCAAACCCCCTCCTCTGCCTCGCTCCAACACAGGTGAGTGGCATGGCGGGCCTTGGCACGGG
CTCTGCTCCCACTGGCCTGGTGCTCCCGGTGACGGCAATGTGGCTCCTCTCTGCTGAGGGCGCCCACACGGCTGGGAGTG
GTCCCTGGCCTGCCTCAGCACCATTGTTCTCCGGTGTTTGGGAGGAGGCTGACCCGTGGGAGGTGTCTGCCCTGCTCAGG
AAGCTGGGGCTGGCAGCTTCAGAAGCAGTAGGGGCCCTGTGGAGCCTCTGCCCAGCATCCTCCGTGGGGAGTCCAGCACT
GCGGGCTCCAGGAGGCTCTGCGGCAGCCTCCCTCCCTGCCTGGGCCCAGGTTTGGACACCTGAGCCCGCCTGCGCACTCT
GGGCCCCCACCCCACTCGGCACCGTGCTTCTCGCCAGGCCCTCTGGCTCTTCCCTGTGGCTGCAGATGGCACTTAGCGGC
CTAGGACGTCTATTCACGGGAGGAGGGAGGCACTGCCCTCCTCAGGTCTGCCCAAGCAGCTTGTAGCTAGCACTGGGCCC
CGTGCGCGCCCCTGCCGGCCGCTGGCCCTGCCCTCTCTCCTCTGCAGGCACGGGGCCTGTGCTCTCTGCTCGACCTGTGT
GTAGCCCCTCCTCCTGCTGACGTGGCCGCACACGGCCTTCCCTTGCAGTGGCCTCTTTCTCCTCCCTGTACCAGTCCAGC
TGCCAAGGACAGCTGCACAGGAGCGTTTCCTGGGCAGGTATCGCCTCTCAGAGGGAAGCGGTTGGCTGCAGAGCGCCACT
CTGCCTCATAGGTGCTGTGCTCGTCGCCTCATCCGCCCACCCCCATGGTCCGTCTGCCTCCATTGCCCTGGGGAGCAGGT
CCCGACTCGCATGAGGACGTCTGTGCAGAATGTCTTTGGCTTGGCCAGCGGGATCCCCTTGACTTGGTCCCTTTGTGGCT
GAGCCCTGTTCCCACGCTGTGCGAGCACTCCCGGCCCAGCTTCAGGCCTGAGGGGTGGGGGTGGCCTGAGTCTCCATGGT
GACATCAGCTGAGCTGCAGACTCTGATGGGTGGCAGCTGTTTAGGGGGAAGCCCACCCCTGGGCCTGCACCGAGCGGGCC
TTGCCCTGGCCTTTGGTGGCTCCCCTGGCCTCTGGAACCCACAGATGGGGCTGCCTCAAGTCCCAGGTTGACCAGGGGCC
CTGCAGACCGACCTCTGCCTGTTGCCCCCAAGCCCTGGTGGGGAGTGCTGTGACCTGCATGGTGCTCCCCTGCCAGGTCT
CCACGTGCAGACGAGCTGGTTTGGAAGGGCTGCGTGGGACGGGCCCTGGGGTGGCTGACTGCGCGTGTGCAGGGCTGTGG
GGCGCCCGGGGGCTGTGATGGTCCCCTCTGTTGCTGCTTCTACTTCCTCTCCCCCTGTCCTGACGCTGGCACAGGAAATG
CTGCTTTGGGACCTCCCACCCTCTCTCCTTAGCGTCCCCAGCTGTGGGTCTGGCTTGGAGTTGGAGGGTGAGCCTCTGCT
CTTGGGAGCAGTCTGTTTGCAAACAGGGACTTCCCCCACGTCACGGAGTCTCCGCAGCTCTCCTCGGTTACGAGGGCTGG
TTTCAGGCTCCCGCTCTTTTAGAGCTGAGGCCCGTCGGGCGGAGAGCGTCTTGCCCCTGCCTACCTGGAGGCACAGGGGT
GGCTGCTGGTGGACACTAGGGTGGGCAGAGCCGATTGCCTGCCCAACCCCCGGGCACTCATGCAGGAGAGGCCTGTGTCG
GGGTCACGTGCAGGCCTTCCCAGCGTCCTCCCTGCCCGCTCGGTGGATGGCAGCAGTAAGCAGAGCCCTGGGGAGGCTCG
CAGGGCTGCTGTCCCTCTGGTCAGGAGAAGGCTGGTTCTCGGAGGCCACGTCAGGGCCAGGGCCTGGCCCAGCCCCACAT
CCAGCAGCCCCGTCTGTGTCCTCCCAGACTCCGCCGTGGTCATGGAGGAGGGAAGTCCGGGCGAGGTTCCTGTGCTGGTG
GAGCCCCCAGGGTTGGAGGACGTTGAGGCAGCGCTAGGCATGGACAGGCGCACGGATGCCTACAGCAGGGTGAGTGTGGC
TCAGAGCCTGGACCCTGCTGACCTCGGGGGGCTCCTTAGGGGAGGCAGGGCTCTGCGTGGGTGTGCCTGCACCCTGGGAA
CTGGCTCTGAACTTGGGGGAGATGTTCTTCCACATCCCTCGTGCACAGACGGTCTGCACTTTGCAGCCATCCACCTGGGC
CGGCCCTGGCTGCTGGGCAGCCTGTGGTCTCAGGGGATGCTGATACCTCTGCTCACGCAGTGTGGGGCACAGCTGGTGGC
AGTGCTGCTGCGTCAACGGGCGGGGGCCGTAGCCTGGTGCTCGGGCTGGTCTGTGGCCCTGGGATGGAGGACAGATAGGG
CCTCACCACCTCCAGGTCAACCCCAGGTGGGCTCGAGGGTGCCTGCTGACAGGGGTTCTCTTTGGGATGGTCCTTTCTAG
TCGTCCTCAGTCTCCAGCCAGGAGGAGAAGTCGCTCCACGCGGAGGAGCTGGTTGGCAGGGGCATCCCCATCGAGCGAGT
CGTCTCCTCGGAGGGTGGCCGGCCCTCTGTGGACCTCTCCTTCCAGCCCTCGCAGCCCCTGAGCAAGTCCAGCTCCTCTC
CCGAGCTGCAGACTCTGCAGGACATCCTCGGGGACCCTGGGGACAAGGCCGACGTGGGCCGGCTGAGCCCTGAGGTTAAG
GCCCGGTCACAGTCAGGGACCCTGGACGGGGAAAGTGCTGCCTGGTCGGCCTCGGGCGAAGACAGTCGGGGCCAGCCCGA
GGGTCCCTTGCCTTCCAGCTCCCCCCGCTCGCCCAGTGGCCTCCGGCCCCGAGGTTACACCATCTCCGACTCGGCCCCAT
CACGCAGGGGCAAGAGAGTAGAGAGGGACGCCTTAAAGAGCAGAGCCACAGCCTCCAATGCAGAGAAAGTGCCAGGCATC
AACCCCAGGTGGGCCTCTTGCTTCCGGGCGGGGCTCCTGACACCTCTCCTGCGGGAACCTGGTGCCTCACTTGCCCCAGG
CCGAGCGGGCTGGGGTGGGGTCCTCGCCTGTGCCCTAGGGCTGGCTGGAACCCCTGGGAGGGCGGTGGAGTGGGAGATGG
CCAGGCTCTGTGTTCCTCCCTGTGGGCTGTGGCTGCCCTGGCCAGGCCCTCACCTGGGTGCCCACCATCCCCTCCCTGTG
CAGTTTCGTGTTCCTGCAGCTCTACCATTCCCCCTTCTTTGGCGACGAGTCAAACAAGCCAATCCTGCTGCCCAATGAGG
TAGGCGTGGCCTCCCTCTCCTGCATCCGCTGGAGCTGTGTGGCTCGGGTGAATGGTGGGGGGCCCAGCTCTGCTGCTGGG
AGCTCAGGCTTGCAGAGGGCTCTGGCCTAAGCTCCCTGTGGCAGCCTGCCGTGACCGGCCTGGGTGGGGCGGCCTCCTGT
GGACGGGCGTCTGGGGCTCAGGCAGGGCTCTGTGTGCCACAGTCACAGTCCTTTGAGCGGTCGGTGCAGCTCCTCGACCA
GATCCCATCATACGACACCCACAAGATCGCCGTCCTGTATGTTGGAGAAGGCCAGGTGAGGCTGCGGGGCCGGCCTAGGT
GCCTGGACAGGGCCAGCTGGGCCTCAGCCTGCAGTGGGTAGGGAGTCTGGGCCCCCAACGCCCCACAGAGCTCAACACTG
CCGGGTCCCCTACAGCATGAAGTGCTCATTGAGCTCTGTGCCAGGTGCTGCTCTGAGTGCTGGGGACCCCGGTGCGAGTG
ACAGGTTAGCGTGGGAGCACCCGGCACACCAAGGAGTGGGAAGGACTGGGCGGGTGGCACCGGTCGCAGGGCTGGGGAGG
GCGCTGTTGGTCAGTGAGCTGACAGCTGAGTGGTGAGGGAGCGGGCAGGGGGAGCCTGCATAAGGGGTGGGGGCATCCCA
CACACCAGCAGCGGGGGCCGGGCGCACCCTGCCCAGCTTGAGCACTGGTGCTGGGCGAGCACGGGAGCCGACAGGATGGG
CAGCCTCAGCGCCCTATAGGCTGCACCTTCATCCCAAGGGAAAGGGCAGGGCCTGGGCTGCTTCTGAGCAGAGGGCACAT
GGCCTGACTCCGCCCAGTCTCAGTGAGTCCCTCCTGCTGTGTGGCTCGAGGAGGTGGGTGGTGATGGTTCCCGTGGGAGT
GGGGTAGGCCCCTGGGGGCAGGCTGCTGAGGGGCCAGGGCCCCGGGTGTGCTTTGAGTGTGGAGCTCCCTGATTTTGCCG
GCCAGGCACACACGGGGCTGAGGGAAGAGAGGGAGTCAAGGATGACACCCGATGTCTGGCCTGGGTGGCTGCTGGAATGG
ATGGTCTTGTCTGCCTCAGGGATCAGAGTGGGGCTCCCGGCAGAGCCTGCTGGGCACCCCCACCCTCTGCGGGGCAGGGC
CCGGCCCGGGAGTGATGCCACCCTGCCTCTCCCCTCTCCCCACAGAGCAACAGCGAGCTCGCCATCCTGTCCAATGAGCA
TGGCTCCTACAGGTACACGGAGTTCCTGACGGGCCTGGGCCGGCTCATCGAGCTGAAGGACTGCCAGCCGGACAAGGTGT
ACCTGGGAGGCCTGGACGTGTGTGGTGAGGACGGCCAGTTCACCTACTGCTGGCACGATGACATCATGCAAGGTACGGCC
TGGCGCCTACCCGCTCCTGCTGCCCCAGGCCTCAGGGCACGGCTCCCATCCAGTCCTGCTACCCCACGCCCTGGGGCATG
GCCCTGGCACCCCCACCTGCTCCAGCTCCCCACGCCTCAGGTTCCGAGCCTAACAGCGTGGGCATGGAGGCAGTGATGGG
GCTGGTGGCTTTGCGTCCCAAAGCCCTGCCCCTGGGGAGAGCCGAGGACCACTGGCCAGGCACCAGAGGACGTGGTCCCC
GCAGGCCCCCAGAGCCCCTGGAGTAATCAGGAGGTGCCCCAGTGCAAGGCACAGAGGGCCTCAGCACTGGCCCCACAAAC
CCATCCGGCCCTGCTCACCCTCAGCCGTCTTCCACATCGCCACCCTGATGCCCACCAAGGACGTGGACAAGCACCGCTGC
GACAAGAAGCGCCACCTGGGCAACGACTTTGTGTCCATTGTCTACAATGACTCCGGTGAGGACTTCAAGCTTGGCACCAT
CAAGGTGAGTGAGGGGCCGTCAGTGAGGCTGGGCCCCAGGCAGGTGCCCACTGCTGTGTCCCGGGTTGGTGGCAGGTCCT
CCTCCCTGAGCTTCGGTCACGAGGAGCAGGAGGAGAGGCCGCAGTGCTCAGGGCCCCGTGGGCACGAGCTTCACCCCGAG
CCTGCGTTGTGTCCTCTGTGCCCTGAAGCCTGTGGCGCCTGCTGCTGAGTGTCTGTCAGGAGTAACTGGCAAGTGCAGAC
TGGGTGTGCTGGGTGGGCACAGTGTAGTTGGTGCTTCCTGTCTGTCCGGCGCGGCCCTTGGGCCCCCACCATCTCCCCAG
TGGCAGCTGTCAGGCTGCTCAGTTGGTTATCGCCACGCACCACTAGGCAGCAACCAGCGTCACCCTCTTCCTGGAGGTGG
GCTGGGTCGGCCAGTGTCACAGCACGGTCCGGGTGAGCCCCAGCATGGCGGGGAGAGCTGGCATGGCCCAGGCAGGGCAG
ATAGGCTGGAGGCCTCACTCCAAGGGCCCCAGGATGCTGAGGCAGCCACTGAACCAAAACCCCGGGGCTGGTAGTCAGAG
TCCAGGAGGGGCAGGAGCATAGGGAGGTGGGCTCTGCTAGATGCCAAGACAACCAGTTGGGGGGGGGGGGGCACCTGGGC
GGCTGAGGAGGGTGTGGTGGTGCCGAGATGGGGTGCACGGCTCACTTCATGGCTGGGCAGACGGATTCGGACGTGTGGCT
GCAGACACCCTGGGGGCCCCAGTGAGTGGAGGTGCCCCAGCAATTAGAGGTGTCTTGCCTGTGGCTGCAGCATATGTGGG
TGCTGCGCCCAGATGTGGAGGGGGCTTGGCCTGGGGGAGGCCAGACAAACACAGCCCCGCTGCCAGAGGGGAAAGTTCAG
GGGCAGATGCTGCCCATGGAGCTGACAGGTGTCTAGCAGTGCAACCAGGCAGTAGCCGAGATCAGCCTTCAGCACACGCT
GTGTGCGGGGATGACCCTTTCTCTTGTCCGGGCAGGGCCAGTTCAACTTTGTCCACGTGATCGTCACCCCGCTGGACTAC
GAGTGCAACCTGGTGTCCCTGCAGTGCAGGAAAGGTAGGGCCGGGTGGGGCCCTGCAGTGCAGGAAAGGTAGGGCCGGGT
GGGGCCCTGCAGTGTGGCGCCAAGAGCCCTGGGCCTGGCGTGACCACCAAGTCTCCCCAGACATGGAGGGCCTTGTGGAC
ACCAGCGTGGCCAAGATCGTGTCTGACCGCAACCTGCCCTTCGTGGCCCGCCAGATGGCCCTGCACGCAAATGTGAGTGG
GGGTGGGTCCAGGCGTGAGCTGGTGGGACAGGCCCAGGTGCCACCTGATAGTGAGCTCACCCCCTGCCTACGTCCCCAGA
TGGCCTCACAGGTGCATCATAGCCGCTCCAACCCCACCGATATCTACCCCTCCAAGTGGATTGCCCGGCTCCGCCACATC
AAGCGGCTCCGCCAGCGGGTAGGGAATATGGGGCTCCCTCAGCGGGGTGTGCTGGCTGCCCAAGCTGTGGGGCGGGTGTG
TGGGCAGAGCGGTTGCCACGCCTCCCAGACTTACTGCCCAAGCCGCCTCTGCCTTCAGATCTGCGAGGAAGCCGCCTACT
CCAACCCCAGCCTACCTCTGGTGCACCCTCCGTCCCATAGCAAAGCCCCTGCACAGACTCCAGCCGAGCCCACACCTGGC
TATGAGGTGGGCCAGCGGAAGCGCCTCATCTCCTCGGTGGAGGACTTCACCGAGTTTGTGTGAGGCCGGGGCCCTCCCTC
CTGCACTGGCCTTGGACGGTATTGCCTGTCAGTGAAATAAATAAAGTCCTGACCCCAGTGCACAGACATAGAGGCACAGA
TTGC
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| Primary source |
RefSeq : NM_000548.3 (GI:116256351)
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| Name |
Tuberous sclerosis 2 (TSC2), transcript variant 1
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| Type of transcript |
mRNA
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| Organism |
Homo sapiens
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| Length |
5675 nt
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| Map |
16p13.3
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| Location |
Chromosome 16 (NC_000016.9) strand : +
| 2097989...2098065 | 2098587...2098753 | 2100400...2100486 | 2103342...2103452 |
| 2104296...2104440 | 2105402...2105519 | 2106196...2106244 | 2106644...2106769 |
| 2107105...2107178 | 2108747...2108873 | 2110670...2110813 | 2111871...2112008 |
| 2112497...2112600 | 2112972...2113053 | 2114272...2114427 | 2115519...2115635 |
| 2120456...2120578 | 2121510...2121616 | 2121784...2121934 | 2122241...2122363 |
| 2122849...2122983 | 2124200...2124389 | 2125799...2125892 | 2126068...2126170 |
| 2126491...2126585 | 2127598...2127726 | 2129032...2129196 | 2129276...2129428 |
| 2129557...2129669 | 2130165...2130377 | 2131595...2131798 | 2132436...2132504 |
| 2133695...2133816 | 2134228...2134715 | 2134951...2135026 | 2135230...2135322 |
| 2136193...2136379 | 2136732...2136871 | 2137863...2137941 | 2138048...2138139 |
| 2138227...2138325 | 2138446...2138712 |
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| Exon(s) |
Start |
End |
Length |
is coding |
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Exon 1
|
1
|
77
|
77
|
1
|
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Exon 2
|
78
|
244
|
167
|
1
|
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Exon 3
|
245
|
331
|
87
|
1
|
|
Exon 4
|
332
|
442
|
111
|
1
|
|
Exon 5
|
443
|
587
|
145
|
1
|
|
Exon 6
|
588
|
705
|
118
|
1
|
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Exon 7
|
706
|
754
|
49
|
1
|
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Exon 8
|
755
|
880
|
126
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1
|
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Exon 9
|
881
|
954
|
74
|
1
|
|
Exon 10
|
955
|
1081
|
127
|
1
|
|
Exon 11
|
1082
|
1225
|
144
|
1
|
|
Exon 12
|
1226
|
1363
|
138
|
1
|
|
Exon 13
|
1364
|
1467
|
104
|
1
|
|
Exon 14
|
1468
|
1549
|
82
|
1
|
|
Exon 15
|
1550
|
1705
|
156
|
1
|
|
Exon 16
|
1706
|
1822
|
117
|
1
|
|
Exon 17
|
1823
|
1945
|
123
|
1
|
|
Exon 18
|
1946
|
2052
|
107
|
1
|
|
Exon 19
|
2053
|
2203
|
151
|
1
|
|
Exon 20
|
2204
|
2326
|
123
|
1
|
|
Exon 21
|
2327
|
2461
|
135
|
1
|
|
Exon 22
|
2462
|
2651
|
190
|
1
|
|
Exon 23
|
2652
|
2745
|
94
|
1
|
|
Exon 24
|
2746
|
2848
|
103
|
1
|
|
Exon 25
|
2849
|
2943
|
95
|
1
|
|
Exon 26
|
2944
|
3072
|
129
|
1
|
|
Exon 27a
|
3073
|
3237
|
165
|
1
|
|
Exon 28
|
3238
|
3390
|
153
|
1
|
|
Exon 29
|
3391
|
3503
|
113
|
1
|
|
Exon 30
|
3504
|
3716
|
213
|
1
|
|
Exon 31
|
3717
|
3920
|
204
|
1
|
|
Exon 32
|
3921
|
3989
|
69
|
1
|
|
Exon 33
|
3990
|
4111
|
122
|
1
|
|
Exon 34
|
4112
|
4599
|
488
|
1
|
|
Exon 35
|
4600
|
4675
|
76
|
1
|
|
Exon 36
|
4676
|
4768
|
93
|
1
|
|
Exon 37
|
4769
|
4955
|
187
|
1
|
|
Exon 38
|
4956
|
5095
|
140
|
1
|
|
Exon 39
|
5096
|
5174
|
79
|
1
|
|
Exon 40
|
5175
|
5266
|
92
|
1
|
|
Exon 41
|
5267
|
5365
|
99
|
1
|
|
Exon 42
|
5366
|
5632
|
267
|
1
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Primary source |
NCBI : CCDS10458
|
| Nucleotide |
TSC2, mRNA isoform 1[NM_000548.3] : 107...5530
|
| Length |
5424
|
| Location |
Chromosome 16 (NC_000016.9) strand : +
| 2098616...2098753 | 2100400...2100486 | 2103342...2103452 | 2104296...2104440 |
| 2105402...2105519 | 2106196...2106244 | 2106644...2106769 | 2107105...2107178 |
| 2108747...2108873 | 2110670...2110813 | 2111871...2112008 | 2112497...2112600 |
| 2112972...2113053 | 2114272...2114427 | 2115519...2115635 | 2120456...2120578 |
| 2121510...2121616 | 2121784...2121934 | 2122241...2122363 | 2122849...2122983 |
| 2124200...2124389 | 2125799...2125892 | 2126068...2126170 | 2126491...2126585 |
| 2127598...2127726 | 2129032...2129196 | 2129276...2129428 | 2129557...2129669 |
| 2130165...2130377 | 2131595...2131798 | 2132436...2132504 | 2133695...2133816 |
| 2134228...2134715 | 2134951...2135026 | 2135230...2135322 | 2136193...2136379 |
| 2136732...2136871 | 2137863...2137941 | 2138048...2138139 | 2138227...2138325 |
| 2138446...2138610 |
|
| Start codon |
1
|
| Translation |
NP_000539.2 |
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
CCGGCGGCGT |
CCCGGGGCCA |
GGGGGGTGCG |
CCTTTCTCCG |
CGTCGGGGCG |
GCCCGGAGCG |
CGGTGGCGCG |
GCGCGGGAGG |
|
| 81 |
GGTTTTCTGG |
TGCGTCCTGG |
TCCACCATGG |
CCAAACCAAC |
AAGCAAAGAT |
TCAGGCTTGA |
AGGAGAAGTT |
TAAGATTCTG |
|
| 161 |
TTGGGACTGG |
GAACACCGAG |
GCCAAATCCC |
AGGTCTGCAG |
AGGGTAAACA |
GACGGAGTTT |
ATCATCACCG |
CGGAAATACT |
|
| 241 |
GAGAGAACTG |
AGCATGGAAT |
GTGGCCTCAA |
CAATCGCATC |
CGGATGATAG |
GGCAGATTTG |
TGAAGTCGCA |
AAAACCAAGA |
|
| 321 |
AATTTGAAGA |
GCACGCAGTG |
GAAGCACTCT |
GGAAGGCGGT |
CGCGGATCTG |
TTGCAGCCGG |
AGCGGCCGCT |
GGAGGCCCGG |
|
| 401 |
CACGCGGTGC |
TGGCTCTGCT |
GAAGGCCATC |
GTGCAGGGGC |
AGGGCGAGCG |
TTTGGGGGTC |
CTCAGAGCCC |
TCTTCTTTAA |
|
| 481 |
GGTCATCAAG |
GATTACCCTT |
CCAACGAAGA |
CCTTCACGAA |
AGGCTGGAGG |
TTTTCAAGGC |
CCTCACAGAC |
AATGGGAGAC |
|
| 561 |
ACATCACCTA |
CTTGGAGGAA |
GAGCTGGCTG |
ACTTTGTCCT |
GCAGTGGATG |
GATGTTGGCT |
TGTCCTCGGA |
ATTCCTTCTG |
|
| 641 |
GTGCTGGTGA |
ACTTGGTCAA |
ATTCAATAGC |
TGTTACCTCG |
ACGAGTACAT |
CGCAAGGATG |
GTTCAGATGA |
TCTGTCTGCT |
|
| 721 |
GTGCGTCCGG |
ACCGCGTCCT |
CTGTGGACAT |
AGAGGTCTCC |
CTGCAGGTGC |
TGGACGCCGT |
GGTCTGCTAC |
AACTGCCTGC |
|
| 801 |
CGGCTGAGAG |
CCTCCCGCTG |
TTCATCGTTA |
CCCTCTGTCG |
CACCATCAAC |
GTCAAGGAGC |
TCTGCGAGCC |
TTGCTGGAAG |
|
| 881 |
CTGATGCGGA |
ACCTCCTTGG |
CACCCACCTG |
GGCCACAGCG |
CCATCTACAA |
CATGTGCCAC |
CTCATGGAGG |
ACAGAGCCTA |
|
| 961 |
CATGGAGGAC |
GCGCCCCTGC |
TGAGAGGAGC |
CGTGTTTTTT |
GTGGGCATGG |
CTCTCTGGGG |
AGCCCACCGG |
CTCTATTCTC |
|
| 1041 |
TCAGGAACTC |
GCCGACATCT |
GTGTTGCCAT |
CATTTTACCA |
GGCCATGGCA |
TGTCCGAACG |
AGGTGGTGTC |
CTATGAGATC |
|
| 1121 |
GTCCTGTCCA |
TCACCAGGCT |
CATCAAGAAG |
TATAGGAAGG |
AGCTCCAGGT |
GGTGGCGTGG |
GACATTCTGC |
TGAACATCAT |
|
| 1201 |
CGAACGGCTC |
CTTCAGCAGC |
TCCAGACCTT |
GGACAGCCCG |
GAGCTCAGGA |
CCATCGTCCA |
TGACCTGTTG |
ACCACGGTGG |
|
| 1281 |
AGGAGCTGTG |
TGACCAGAAC |
GAGTTCCACG |
GGTCTCAGGA |
GAGATACTTT |
GAACTGGTGG |
AGAGATGTGC |
GGACCAGAGG |
|
| 1361 |
CCTGAGTCCT |
CCCTCCTGAA |
CCTGATCTCC |
TATAGAGCGC |
AGTCCATCCA |
CCCGGCCAAG |
GACGGCTGGA |
TTCAGAACCT |
|
| 1441 |
GCAGGCGCTG |
ATGGAGAGAT |
TCTTCAGGAG |
CGAGTCCCGA |
GGCGCCGTGC |
GCATCAAGGT |
GCTGGACGTG |
CTGTCCTTTG |
|
| 1521 |
TGCTGCTCAT |
CAACAGGCAG |
TTCTATGAGG |
AGGAGCTGAT |
TAACTCAGTG |
GTCATCTCGC |
AGCTCTCCCA |
CATCCCCGAG |
|
| 1601 |
GATAAAGACC |
ACCAGGTCCG |
AAAGCTGGCC |
ACCCAGTTGC |
TGGTGGACCT |
GGCAGAGGGC |
TGCCACACAC |
ACCACTTCAA |
|
| 1681 |
CAGCCTGCTG |
GACATCATCG |
AGAAGGTGAT |
GGCCCGCTCC |
CTCTCCCCAC |
CCCCGGAGCT |
GGAAGAAAGG |
GATGTGGCCG |
|
| 1761 |
CATACTCGGC |
CTCCTTGGAG |
GATGTGAAGA |
CAGCCGTCCT |
GGGGCTTCTG |
GTCATCCTTC |
AGACCAAGCT |
GTACACCCTG |
|
| 1841 |
CCTGCAAGCC |
ACGCCACGCG |
TGTGTATGAG |
ATGCTGGTCA |
GCCACATTCA |
GCTCCACTAC |
AAGCACAGCT |
ACACCCTGCC |
|
| 1921 |
AATCGCGAGC |
AGCATCCGGC |
TGCAGGCCTT |
TGACTTCCTG |
TTGCTGCTGC |
GGGCCGACTC |
ACTGCACCGC |
CTGGGCCTGC |
|
| 2001 |
CCAACAAGGA |
TGGAGTCGTG |
CGGTTCAGCC |
CCTACTGCGT |
CTGCGACTAC |
ATGGAGCCAG |
AGAGAGGCTC |
TGAGAAGAAG |
|
| 2081 |
ACCAGCGGCC |
CCCTTTCTCC |
TCCCACAGGG |
CCTCCTGGCC |
CGGCGCCTGC |
AGGCCCCGCC |
GTGCGGCTGG |
GGTCCGTGCC |
|
| 2161 |
CTACTCCCTG |
CTCTTCCGCG |
TCCTGCTGCA |
GTGCTTGAAG |
CAGGAGTCTG |
ACTGGAAGGT |
GCTGAAGCTG |
GTTCTGGGCA |
|
| 2241 |
GGCTGCCTGA |
GTCCCTGCGC |
TATAAAGTGC |
TCATCTTTAC |
TTCCCCTTGC |
AGTGTGGACC |
AGCTGTGCTC |
TGCTCTCTGC |
|
| 2321 |
TCCATGCTTT |
CAGGCCCAAA |
GACACTGGAG |
CGGCTCCGAG |
GCGCCCCAGA |
AGGCTTCTCC |
AGAACTGACT |
TGCACCTGGC |
|
| 2401 |
CGTGGTTCCA |
GTGCTGACAG |
CATTAATCTC |
TTACCATAAC |
TACCTGGACA |
AAACCAAACA |
GCGCGAGATG |
GTCTACTGCC |
|
| 2481 |
TGGAGCAGGG |
CCTCATCCAC |
CGCTGTGCCA |
GCCAGTGCGT |
CGTGGCCTTG |
TCCATCTGCA |
GCGTGGAGAT |
GCCTGACATC |
|
| 2561 |
ATCATCAAGG |
CGCTGCCTGT |
TCTGGTGGTG |
AAGCTCACGC |
ACATCTCAGC |
CACAGCCAGC |
ATGGCCGTCC |
CACTGCTGGA |
|
| 2641 |
GTTCCTGTCC |
ACTCTGGCCA |
GGCTGCCGCA |
CCTCTACAGG |
AACTTTGCCG |
CGGAGCAGTA |
TGCCAGTGTG |
TTCGCCATCT |
|
| 2721 |
CCCTGCCGTA |
CACCAACCCC |
TCCAAGTTTA |
ATCAGTACAT |
CGTGTGTCTG |
GCCCATCACG |
TCATAGCCAT |
GTGGTTCATC |
|
| 2801 |
AGGTGCCGCC |
TGCCCTTCCG |
GAAGGATTTT |
GTCCCTTTCA |
TCACTAAGGG |
CCTGCGGTCC |
AATGTCCTCT |
TGTCTTTTGA |
|
| 2881 |
TGACACCCCC |
GAGAAGGACA |
GCTTCAGGGC |
CCGGAGTACT |
AGTCTCAACG |
AGAGACCCAA |
GAGTCTGAGG |
ATAGCCAGAC |
|
| 2961 |
CCCCCAAACA |
AGGCTTGAAT |
AACTCTCCAC |
CCGTGAAAGA |
ATTCAAGGAG |
AGCTCTGCAG |
CCGAGGCCTT |
CCGGTGCCGC |
|
| 3041 |
AGCATCAGTG |
TGTCTGAACA |
TGTGGTCCGC |
AGCAGGATAC |
AGACGTCCCT |
CACCAGTGCC |
AGCTTGGGGT |
CTGCAGATGA |
|
| 3121 |
GAACTCCGTG |
GCCCAGGCTG |
ACGATAGCCT |
GAAAAACCTC |
CACCTGGAGC |
TCACGGAAAC |
CTGTCTGGAC |
ATGATGGCTC |
|
| 3201 |
GATACGTCTT |
CTCCAACTTC |
ACGGCTGTCC |
CGAAGAGGTC |
TCCTGTGGGC |
GAGTTCCTCC |
TAGCGGGTGG |
CAGGACCAAA |
|
| 3281 |
ACCTGGCTGG |
TTGGGAACAA |
GCTTGTCACT |
GTGACGACAA |
GCGTGGGAAC |
CGGGACCCGG |
TCGTTACTAG |
GCCTGGACTC |
|
| 3361 |
GGGGGAGCTG |
CAGTCCGGCC |
CGGAGTCGAG |
CTCCAGCCCC |
GGGGTGCATG |
TGAGACAGAC |
CAAGGAGGCG |
CCGGCCAAGC |
|
| 3441 |
TGGAGTCCCA |
GGCTGGGCAG |
CAGGTGTCCC |
GTGGGGCCCG |
GGATCGGGTC |
CGTTCCATGT |
CGGGGGGCCA |
TGGTCTTCGA |
|
| 3521 |
GTTGGCGCCC |
TGGACGTGCC |
GGCCTCCCAG |
TTCCTGGGCA |
GTGCCACTTC |
TCCAGGACCA |
CGGACTGCAC |
CAGCCGCGAA |
|
| 3601 |
ACCTGAGAAG |
GCCTCAGCTG |
GCACCCGGGT |
TCCTGTGCAG |
GAGAAGACGA |
ACCTGGCGGC |
CTATGTGCCC |
CTGCTGACCC |
|
| 3681 |
AGGGCTGGGC |
GGAGATCCTG |
GTCCGGAGGC |
CCACAGGGAA |
CACCAGCTGG |
CTGATGAGCC |
TGGAGAACCC |
GCTCAGCCCT |
|
| 3761 |
TTCTCCTCGG |
ACATCAACAA |
CATGCCCCTG |
CAGGAGCTGT |
CTAACGCCCT |
CATGGCGGCT |
GAGCGCTTCA |
AGGAGCACCG |
|
| 3841 |
GGACACAGCC |
CTGTACAAGT |
CACTGTCGGT |
GCCGGCAGCC |
AGCACGGCCA |
AACCCCCTCC |
TCTGCCTCGC |
TCCAACACAG |
|
| 3921 |
TGGCCTCTTT |
CTCCTCCCTG |
TACCAGTCCA |
GCTGCCAAGG |
ACAGCTGCAC |
AGGAGCGTTT |
CCTGGGCAGA |
CTCCGCCGTG |
|
| 4001 |
GTCATGGAGG |
AGGGAAGTCC |
GGGCGAGGTT |
CCTGTGCTGG |
TGGAGCCCCC |
AGGGTTGGAG |
GACGTTGAGG |
CAGCGCTAGG |
|
| 4081 |
CATGGACAGG |
CGCACGGATG |
CCTACAGCAG |
GTCGTCCTCA |
GTCTCCAGCC |
AGGAGGAGAA |
GTCGCTCCAC |
GCGGAGGAGC |
|
| 4161 |
TGGTTGGCAG |
GGGCATCCCC |
ATCGAGCGAG |
TCGTCTCCTC |
GGAGGGTGGC |
CGGCCCTCTG |
TGGACCTCTC |
CTTCCAGCCC |
|
| 4241 |
TCGCAGCCCC |
TGAGCAAGTC |
CAGCTCCTCT |
CCCGAGCTGC |
AGACTCTGCA |
GGACATCCTC |
GGGGACCCTG |
GGGACAAGGC |
|
| 4321 |
CGACGTGGGC |
CGGCTGAGCC |
CTGAGGTTAA |
GGCCCGGTCA |
CAGTCAGGGA |
CCCTGGACGG |
GGAAAGTGCT |
GCCTGGTCGG |
|
| 4401 |
CCTCGGGCGA |
AGACAGTCGG |
GGCCAGCCCG |
AGGGTCCCTT |
GCCTTCCAGC |
TCCCCCCGCT |
CGCCCAGTGG |
CCTCCGGCCC |
|
| 4481 |
CGAGGTTACA |
CCATCTCCGA |
CTCGGCCCCA |
TCACGCAGGG |
GCAAGAGAGT |
AGAGAGGGAC |
GCCTTAAAGA |
GCAGAGCCAC |
|
| 4561 |
AGCCTCCAAT |
GCAGAGAAAG |
TGCCAGGCAT |
CAACCCCAGT |
TTCGTGTTCC |
TGCAGCTCTA |
CCATTCCCCC |
TTCTTTGGCG |
|
| 4641 |
ACGAGTCAAA |
CAAGCCAATC |
CTGCTGCCCA |
ATGAGTCACA |
GTCCTTTGAG |
CGGTCGGTGC |
AGCTCCTCGA |
CCAGATCCCA |
|
| 4721 |
TCATACGACA |
CCCACAAGAT |
CGCCGTCCTG |
TATGTTGGAG |
AAGGCCAGAG |
CAACAGCGAG |
CTCGCCATCC |
TGTCCAATGA |
|
| 4801 |
GCATGGCTCC |
TACAGGTACA |
CGGAGTTCCT |
GACGGGCCTG |
GGCCGGCTCA |
TCGAGCTGAA |
GGACTGCCAG |
CCGGACAAGG |
|
| 4881 |
TGTACCTGGG |
AGGCCTGGAC |
GTGTGTGGTG |
AGGACGGCCA |
GTTCACCTAC |
TGCTGGCACG |
ATGACATCAT |
GCAAGCCGTC |
|
| 4961 |
TTCCACATCG |
CCACCCTGAT |
GCCCACCAAG |
GACGTGGACA |
AGCACCGCTG |
CGACAAGAAG |
CGCCACCTGG |
GCAACGACTT |
|
| 5041 |
TGTGTCCATT |
GTCTACAATG |
ACTCCGGTGA |
GGACTTCAAG |
CTTGGCACCA |
TCAAGGGCCA |
GTTCAACTTT |
GTCCACGTGA |
|
| 5121 |
TCGTCACCCC |
GCTGGACTAC |
GAGTGCAACC |
TGGTGTCCCT |
GCAGTGCAGG |
AAAGACATGG |
AGGGCCTTGT |
GGACACCAGC |
|
| 5201 |
GTGGCCAAGA |
TCGTGTCTGA |
CCGCAACCTG |
CCCTTCGTGG |
CCCGCCAGAT |
GGCCCTGCAC |
GCAAATATGG |
CCTCACAGGT |
|
| 5281 |
GCATCATAGC |
CGCTCCAACC |
CCACCGATAT |
CTACCCCTCC |
AAGTGGATTG |
CCCGGCTCCG |
CCACATCAAG |
CGGCTCCGCC |
|
| 5361 |
AGCGGATCTG |
CGAGGAAGCC |
GCCTACTCCA |
ACCCCAGCCT |
ACCTCTGGTG |
CACCCTCCGT |
CCCATAGCAA |
AGCCCCTGCA |
|
| 5441 |
CAGACTCCAG |
CCGAGCCCAC |
ACCTGGCTAT |
GAGGTGGGCC |
AGCGGAAGCG |
CCTCATCTCC |
TCGGTGGAGG |
ACTTCACCGA |
|
| 5521 |
GTTTGTGTGA |
GGCCGGGGCC |
CTCCCTCCTG |
CACTGGCCTT |
GGACGGTATT |
GCCTGTCAGT |
GAAATAAATA |
AAGTCCTGAC |
|
| 5601 |
CCCAGTGCAC |
AGACATAGAG |
GCACAGATTG |
CAAAAAAAAA |
AAAAAAAAAA |
AAAAAAAAAA |
AAAAAAAAAA |
AAAAA |
|
|
|
|
|
|
|
|
|
|
|
|
>gi|116256351|ref|NM_000548.3|Tuberous sclerosis 2 (TSC2), transcript variant 1
CCGGCGGCGTCCCGGGGCCAGGGGGGTGCGCCTTTCTCCGCGTCGGGGCGGCCCGGAGCGCGGTGGCGCGGCGCGGGAGG
GGTTTTCTGGTGCGTCCTGGTCCACCATGGCCAAACCAACAAGCAAAGATTCAGGCTTGAAGGAGAAGTTTAAGATTCTG
TTGGGACTGGGAACACCGAGGCCAAATCCCAGGTCTGCAGAGGGTAAACAGACGGAGTTTATCATCACCGCGGAAATACT
GAGAGAACTGAGCATGGAATGTGGCCTCAACAATCGCATCCGGATGATAGGGCAGATTTGTGAAGTCGCAAAAACCAAGA
AATTTGAAGAGCACGCAGTGGAAGCACTCTGGAAGGCGGTCGCGGATCTGTTGCAGCCGGAGCGGCCGCTGGAGGCCCGG
CACGCGGTGCTGGCTCTGCTGAAGGCCATCGTGCAGGGGCAGGGCGAGCGTTTGGGGGTCCTCAGAGCCCTCTTCTTTAA
GGTCATCAAGGATTACCCTTCCAACGAAGACCTTCACGAAAGGCTGGAGGTTTTCAAGGCCCTCACAGACAATGGGAGAC
ACATCACCTACTTGGAGGAAGAGCTGGCTGACTTTGTCCTGCAGTGGATGGATGTTGGCTTGTCCTCGGAATTCCTTCTG
GTGCTGGTGAACTTGGTCAAATTCAATAGCTGTTACCTCGACGAGTACATCGCAAGGATGGTTCAGATGATCTGTCTGCT
GTGCGTCCGGACCGCGTCCTCTGTGGACATAGAGGTCTCCCTGCAGGTGCTGGACGCCGTGGTCTGCTACAACTGCCTGC
CGGCTGAGAGCCTCCCGCTGTTCATCGTTACCCTCTGTCGCACCATCAACGTCAAGGAGCTCTGCGAGCCTTGCTGGAAG
CTGATGCGGAACCTCCTTGGCACCCACCTGGGCCACAGCGCCATCTACAACATGTGCCACCTCATGGAGGACAGAGCCTA
CATGGAGGACGCGCCCCTGCTGAGAGGAGCCGTGTTTTTTGTGGGCATGGCTCTCTGGGGAGCCCACCGGCTCTATTCTC
TCAGGAACTCGCCGACATCTGTGTTGCCATCATTTTACCAGGCCATGGCATGTCCGAACGAGGTGGTGTCCTATGAGATC
GTCCTGTCCATCACCAGGCTCATCAAGAAGTATAGGAAGGAGCTCCAGGTGGTGGCGTGGGACATTCTGCTGAACATCAT
CGAACGGCTCCTTCAGCAGCTCCAGACCTTGGACAGCCCGGAGCTCAGGACCATCGTCCATGACCTGTTGACCACGGTGG
AGGAGCTGTGTGACCAGAACGAGTTCCACGGGTCTCAGGAGAGATACTTTGAACTGGTGGAGAGATGTGCGGACCAGAGG
CCTGAGTCCTCCCTCCTGAACCTGATCTCCTATAGAGCGCAGTCCATCCACCCGGCCAAGGACGGCTGGATTCAGAACCT
GCAGGCGCTGATGGAGAGATTCTTCAGGAGCGAGTCCCGAGGCGCCGTGCGCATCAAGGTGCTGGACGTGCTGTCCTTTG
TGCTGCTCATCAACAGGCAGTTCTATGAGGAGGAGCTGATTAACTCAGTGGTCATCTCGCAGCTCTCCCACATCCCCGAG
GATAAAGACCACCAGGTCCGAAAGCTGGCCACCCAGTTGCTGGTGGACCTGGCAGAGGGCTGCCACACACACCACTTCAA
CAGCCTGCTGGACATCATCGAGAAGGTGATGGCCCGCTCCCTCTCCCCACCCCCGGAGCTGGAAGAAAGGGATGTGGCCG
CATACTCGGCCTCCTTGGAGGATGTGAAGACAGCCGTCCTGGGGCTTCTGGTCATCCTTCAGACCAAGCTGTACACCCTG
CCTGCAAGCCACGCCACGCGTGTGTATGAGATGCTGGTCAGCCACATTCAGCTCCACTACAAGCACAGCTACACCCTGCC
AATCGCGAGCAGCATCCGGCTGCAGGCCTTTGACTTCCTGTTGCTGCTGCGGGCCGACTCACTGCACCGCCTGGGCCTGC
CCAACAAGGATGGAGTCGTGCGGTTCAGCCCCTACTGCGTCTGCGACTACATGGAGCCAGAGAGAGGCTCTGAGAAGAAG
ACCAGCGGCCCCCTTTCTCCTCCCACAGGGCCTCCTGGCCCGGCGCCTGCAGGCCCCGCCGTGCGGCTGGGGTCCGTGCC
CTACTCCCTGCTCTTCCGCGTCCTGCTGCAGTGCTTGAAGCAGGAGTCTGACTGGAAGGTGCTGAAGCTGGTTCTGGGCA
GGCTGCCTGAGTCCCTGCGCTATAAAGTGCTCATCTTTACTTCCCCTTGCAGTGTGGACCAGCTGTGCTCTGCTCTCTGC
TCCATGCTTTCAGGCCCAAAGACACTGGAGCGGCTCCGAGGCGCCCCAGAAGGCTTCTCCAGAACTGACTTGCACCTGGC
CGTGGTTCCAGTGCTGACAGCATTAATCTCTTACCATAACTACCTGGACAAAACCAAACAGCGCGAGATGGTCTACTGCC
TGGAGCAGGGCCTCATCCACCGCTGTGCCAGCCAGTGCGTCGTGGCCTTGTCCATCTGCAGCGTGGAGATGCCTGACATC
ATCATCAAGGCGCTGCCTGTTCTGGTGGTGAAGCTCACGCACATCTCAGCCACAGCCAGCATGGCCGTCCCACTGCTGGA
GTTCCTGTCCACTCTGGCCAGGCTGCCGCACCTCTACAGGAACTTTGCCGCGGAGCAGTATGCCAGTGTGTTCGCCATCT
CCCTGCCGTACACCAACCCCTCCAAGTTTAATCAGTACATCGTGTGTCTGGCCCATCACGTCATAGCCATGTGGTTCATC
AGGTGCCGCCTGCCCTTCCGGAAGGATTTTGTCCCTTTCATCACTAAGGGCCTGCGGTCCAATGTCCTCTTGTCTTTTGA
TGACACCCCCGAGAAGGACAGCTTCAGGGCCCGGAGTACTAGTCTCAACGAGAGACCCAAGAGTCTGAGGATAGCCAGAC
CCCCCAAACAAGGCTTGAATAACTCTCCACCCGTGAAAGAATTCAAGGAGAGCTCTGCAGCCGAGGCCTTCCGGTGCCGC
AGCATCAGTGTGTCTGAACATGTGGTCCGCAGCAGGATACAGACGTCCCTCACCAGTGCCAGCTTGGGGTCTGCAGATGA
GAACTCCGTGGCCCAGGCTGACGATAGCCTGAAAAACCTCCACCTGGAGCTCACGGAAACCTGTCTGGACATGATGGCTC
GATACGTCTTCTCCAACTTCACGGCTGTCCCGAAGAGGTCTCCTGTGGGCGAGTTCCTCCTAGCGGGTGGCAGGACCAAA
ACCTGGCTGGTTGGGAACAAGCTTGTCACTGTGACGACAAGCGTGGGAACCGGGACCCGGTCGTTACTAGGCCTGGACTC
GGGGGAGCTGCAGTCCGGCCCGGAGTCGAGCTCCAGCCCCGGGGTGCATGTGAGACAGACCAAGGAGGCGCCGGCCAAGC
TGGAGTCCCAGGCTGGGCAGCAGGTGTCCCGTGGGGCCCGGGATCGGGTCCGTTCCATGTCGGGGGGCCATGGTCTTCGA
GTTGGCGCCCTGGACGTGCCGGCCTCCCAGTTCCTGGGCAGTGCCACTTCTCCAGGACCACGGACTGCACCAGCCGCGAA
ACCTGAGAAGGCCTCAGCTGGCACCCGGGTTCCTGTGCAGGAGAAGACGAACCTGGCGGCCTATGTGCCCCTGCTGACCC
AGGGCTGGGCGGAGATCCTGGTCCGGAGGCCCACAGGGAACACCAGCTGGCTGATGAGCCTGGAGAACCCGCTCAGCCCT
TTCTCCTCGGACATCAACAACATGCCCCTGCAGGAGCTGTCTAACGCCCTCATGGCGGCTGAGCGCTTCAAGGAGCACCG
GGACACAGCCCTGTACAAGTCACTGTCGGTGCCGGCAGCCAGCACGGCCAAACCCCCTCCTCTGCCTCGCTCCAACACAG
TGGCCTCTTTCTCCTCCCTGTACCAGTCCAGCTGCCAAGGACAGCTGCACAGGAGCGTTTCCTGGGCAGACTCCGCCGTG
GTCATGGAGGAGGGAAGTCCGGGCGAGGTTCCTGTGCTGGTGGAGCCCCCAGGGTTGGAGGACGTTGAGGCAGCGCTAGG
CATGGACAGGCGCACGGATGCCTACAGCAGGTCGTCCTCAGTCTCCAGCCAGGAGGAGAAGTCGCTCCACGCGGAGGAGC
TGGTTGGCAGGGGCATCCCCATCGAGCGAGTCGTCTCCTCGGAGGGTGGCCGGCCCTCTGTGGACCTCTCCTTCCAGCCC
TCGCAGCCCCTGAGCAAGTCCAGCTCCTCTCCCGAGCTGCAGACTCTGCAGGACATCCTCGGGGACCCTGGGGACAAGGC
CGACGTGGGCCGGCTGAGCCCTGAGGTTAAGGCCCGGTCACAGTCAGGGACCCTGGACGGGGAAAGTGCTGCCTGGTCGG
CCTCGGGCGAAGACAGTCGGGGCCAGCCCGAGGGTCCCTTGCCTTCCAGCTCCCCCCGCTCGCCCAGTGGCCTCCGGCCC
CGAGGTTACACCATCTCCGACTCGGCCCCATCACGCAGGGGCAAGAGAGTAGAGAGGGACGCCTTAAAGAGCAGAGCCAC
AGCCTCCAATGCAGAGAAAGTGCCAGGCATCAACCCCAGTTTCGTGTTCCTGCAGCTCTACCATTCCCCCTTCTTTGGCG
ACGAGTCAAACAAGCCAATCCTGCTGCCCAATGAGTCACAGTCCTTTGAGCGGTCGGTGCAGCTCCTCGACCAGATCCCA
TCATACGACACCCACAAGATCGCCGTCCTGTATGTTGGAGAAGGCCAGAGCAACAGCGAGCTCGCCATCCTGTCCAATGA
GCATGGCTCCTACAGGTACACGGAGTTCCTGACGGGCCTGGGCCGGCTCATCGAGCTGAAGGACTGCCAGCCGGACAAGG
TGTACCTGGGAGGCCTGGACGTGTGTGGTGAGGACGGCCAGTTCACCTACTGCTGGCACGATGACATCATGCAAGCCGTC
TTCCACATCGCCACCCTGATGCCCACCAAGGACGTGGACAAGCACCGCTGCGACAAGAAGCGCCACCTGGGCAACGACTT
TGTGTCCATTGTCTACAATGACTCCGGTGAGGACTTCAAGCTTGGCACCATCAAGGGCCAGTTCAACTTTGTCCACGTGA
TCGTCACCCCGCTGGACTACGAGTGCAACCTGGTGTCCCTGCAGTGCAGGAAAGACATGGAGGGCCTTGTGGACACCAGC
GTGGCCAAGATCGTGTCTGACCGCAACCTGCCCTTCGTGGCCCGCCAGATGGCCCTGCACGCAAATATGGCCTCACAGGT
GCATCATAGCCGCTCCAACCCCACCGATATCTACCCCTCCAAGTGGATTGCCCGGCTCCGCCACATCAAGCGGCTCCGCC
AGCGGATCTGCGAGGAAGCCGCCTACTCCAACCCCAGCCTACCTCTGGTGCACCCTCCGTCCCATAGCAAAGCCCCTGCA
CAGACTCCAGCCGAGCCCACACCTGGCTATGAGGTGGGCCAGCGGAAGCGCCTCATCTCCTCGGTGGAGGACTTCACCGA
GTTTGTGTGAGGCCGGGGCCCTCCCTCCTGCACTGGCCTTGGACGGTATTGCCTGTCAGTGAAATAAATAAAGTCCTGAC
CCCAGTGCACAGACATAGAGGCACAGATTGCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
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| Primary source |
RefSeq : NM_001077183.1 (GI:116256349)
|
| Name |
Tuberous sclerosis 2 (TSC2), transcript variant 4
|
| Type of transcript |
mRNA
|
| Organism |
Homo sapiens
|
| Length |
5474 nt
|
| Map |
16p13.3
|
| Location |
Chromosome 16 (NC_000016.9) strand : +
| 2097989...2098065 | 2098587...2098753 | 2100400...2100486 | 2103342...2103452 |
| 2104296...2104440 | 2105402...2105519 | 2106196...2106244 | 2106644...2106769 |
| 2107105...2107178 | 2108747...2108873 | 2110670...2110813 | 2111871...2112008 |
| 2112497...2112600 | 2112972...2113053 | 2114272...2114427 | 2115519...2115635 |
| 2120456...2120578 | 2121510...2121616 | 2121784...2121934 | 2122241...2122363 |
| 2122849...2122983 | 2124200...2124389 | 2125799...2125892 | 2126068...2126170 |
| 2126491...2126585 | 2129035...2129196 | 2129276...2129428 | 2129557...2129669 |
| 2130165...2130377 | 2131595...2131798 | 2133695...2133816 | 2134228...2134715 |
| 2134951...2135026 | 2135230...2135322 | 2136193...2136379 | 2136732...2136871 |
| 2137863...2137941 | 2138048...2138139 | 2138227...2138325 | 2138446...2138712 |
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|
| Exon(s) |
Start |
End |
Length |
is coding |
|
Exon 1
|
1
|
77
|
77
|
1
|
|
Exon 2
|
78
|
244
|
167
|
1
|
|
Exon 3
|
245
|
331
|
87
|
1
|
|
Exon 4
|
332
|
442
|
111
|
1
|
|
Exon 5
|
443
|
587
|
145
|
1
|
|
Exon 6
|
588
|
705
|
118
|
1
|
|
Exon 7
|
706
|
754
|
49
|
1
|
|
Exon 8
|
755
|
880
|
126
|
1
|
|
Exon 9
|
881
|
954
|
74
|
1
|
|
Exon 10
|
955
|
1081
|
127
|
1
|
|
Exon 11
|
1082
|
1225
|
144
|
1
|
|
Exon 12
|
1226
|
1363
|
138
|
1
|
|
Exon 13
|
1364
|
1467
|
104
|
1
|
|
Exon 14
|
1468
|
1549
|
82
|
1
|
|
Exon 15
|
1550
|
1705
|
156
|
1
|
|
Exon 16
|
1706
|
1822
|
117
|
1
|
|
Exon 17
|
1823
|
1945
|
123
|
1
|
|
Exon 18
|
1946
|
2052
|
107
|
1
|
|
Exon 19
|
2053
|
2203
|
151
|
1
|
|
Exon 20
|
2204
|
2326
|
123
|
1
|
|
Exon 21
|
2327
|
2461
|
135
|
1
|
|
Exon 22
|
2462
|
2651
|
190
|
1
|
|
Exon 23
|
2652
|
2745
|
94
|
1
|
|
Exon 24
|
2746
|
2848
|
103
|
1
|
|
Exon 25
|
2849
|
2943
|
95
|
1
|
|
Exon 27b
|
2944
|
3105
|
162
|
1
|
|
Exon 28
|
3106
|
3258
|
153
|
1
|
|
Exon 29
|
3259
|
3371
|
113
|
1
|
|
Exon 30
|
3372
|
3584
|
213
|
1
|
|
Exon 31
|
3585
|
3788
|
204
|
1
|
|
Exon 33
|
3789
|
3910
|
122
|
1
|
|
Exon 34
|
3911
|
4398
|
488
|
1
|
|
Exon 35
|
4399
|
4474
|
76
|
1
|
|
Exon 36
|
4475
|
4567
|
93
|
1
|
|
Exon 37
|
4568
|
4754
|
187
|
1
|
|
Exon 38
|
4755
|
4894
|
140
|
1
|
|
Exon 39
|
4895
|
4973
|
79
|
1
|
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Exon 40
|
4974
|
5065
|
92
|
1
|
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Exon 41
|
5066
|
5164
|
99
|
1
|
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Exon 42
|
5165
|
5431
|
267
|
1
|
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|
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| ID |
Class |
Location |
Mutation |
Length |
is synonymous |
Source |
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| Primary source |
NCBI :
|
| Nucleotide |
TSC2, mRNA isoform 4[NM_001077183.1] : 107...5329
|
| Length |
5223
|
| Location |
Chromosome 16 (NC_000016.9) strand : +
| 2098616...2098753 | 2100400...2100486 | 2103342...2103452 | 2104296...2104440 |
| 2105402...2105519 | 2106196...2106244 | 2106644...2106769 | 2107105...2107178 |
| 2108747...2108873 | 2110670...2110813 | 2111871...2112008 | 2112497...2112600 |
| 2112972...2113053 | 2114272...2114427 | 2115519...2115635 | 2120456...2120578 |
| 2121510...2121616 | 2121784...2121934 | 2122241...2122363 | 2122849...2122983 |
| 2124200...2124389 | 2125799...2125892 | 2126068...2126170 | 2126491...2126585 |
| 2129035...2129196 | 2129276...2129428 | 2129557...2129669 | 2130165...2130377 |
| 2131595...2131798 | 2133695...2133816 | 2134228...2134715 | 2134951...2135026 |
| 2135230...2135322 | 2136193...2136379 | 2136732...2136871 | 2137863...2137941 |
| 2138048...2138139 | 2138227...2138325 | 2138446...2138610 |
|
| Start codon |
1
|
| Translation |
NP_001070651.1 |
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| 1 |
CCGGCGGCGT |
CCCGGGGCCA |
GGGGGGTGCG |
CCTTTCTCCG |
CGTCGGGGCG |
GCCCGGAGCG |
CGGTGGCGCG |
GCGCGGGAGG |
|
| 81 |
GGTTTTCTGG |
TGCGTCCTGG |
TCCACCATGG |
CCAAACCAAC |
AAGCAAAGAT |
TCAGGCTTGA |
AGGAGAAGTT |
TAAGATTCTG |
|
| 161 |
TTGGGACTGG |
GAACACCGAG |
GCCAAATCCC |
AGGTCTGCAG |
AGGGTAAACA |
GACGGAGTTT |
ATCATCACCG |
CGGAAATACT |
|
| 241 |
GAGAGAACTG |
AGCATGGAAT |
GTGGCCTCAA |
CAATCGCATC |
CGGATGATAG |
GGCAGATTTG |
TGAAGTCGCA |
AAAACCAAGA |
|
| 321 |
AATTTGAAGA |
GCACGCAGTG |
GAAGCACTCT |
GGAAGGCGGT |
CGCGGATCTG |
TTGCAGCCGG |
AGCGGCCGCT |
GGAGGCCCGG |
|
| 401 |
CACGCGGTGC |
TGGCTCTGCT |
GAAGGCCATC |
GTGCAGGGGC |
AGGGCGAGCG |
TTTGGGGGTC |
CTCAGAGCCC |
TCTTCTTTAA |
|
| 481 |
GGTCATCAAG |
GATTACCCTT |
CCAACGAAGA |
CCTTCACGAA |
AGGCTGGAGG |
TTTTCAAGGC |
CCTCACAGAC |
AATGGGAGAC |
|
| 561 |
ACATCACCTA |
CTTGGAGGAA |
GAGCTGGCTG |
ACTTTGTCCT |
GCAGTGGATG |
GATGTTGGCT |
TGTCCTCGGA |
ATTCCTTCTG |
|
| 641 |
GTGCTGGTGA |
ACTTGGTCAA |
ATTCAATAGC |
TGTTACCTCG |
ACGAGTACAT |
CGCAAGGATG |
GTTCAGATGA |
TCTGTCTGCT |
|
| 721 |
GTGCGTCCGG |
ACCGCGTCCT |
CTGTGGACAT |
AGAGGTCTCC |
CTGCAGGTGC |
TGGACGCCGT |
GGTCTGCTAC |
AACTGCCTGC |
|
| 801 |
CGGCTGAGAG |
CCTCCCGCTG |
TTCATCGTTA |
CCCTCTGTCG |
CACCATCAAC |
GTCAAGGAGC |
TCTGCGAGCC |
TTGCTGGAAG |
|
| 881 |
CTGATGCGGA |
ACCTCCTTGG |
CACCCACCTG |
GGCCACAGCG |
CCATCTACAA |
CATGTGCCAC |
CTCATGGAGG |
ACAGAGCCTA |
|
| 961 |
CATGGAGGAC |
GCGCCCCTGC |
TGAGAGGAGC |
CGTGTTTTTT |
GTGGGCATGG |
CTCTCTGGGG |
AGCCCACCGG |
CTCTATTCTC |
|
| 1041 |
TCAGGAACTC |
GCCGACATCT |
GTGTTGCCAT |
CATTTTACCA |
GGCCATGGCA |
TGTCCGAACG |
AGGTGGTGTC |
CTATGAGATC |
|
| 1121 |
GTCCTGTCCA |
TCACCAGGCT |
CATCAAGAAG |
TATAGGAAGG |
AGCTCCAGGT |
GGTGGCGTGG |
GACATTCTGC |
TGAACATCAT |
|
| 1201 |
CGAACGGCTC |
CTTCAGCAGC |
TCCAGACCTT |
GGACAGCCCG |
GAGCTCAGGA |
CCATCGTCCA |
TGACCTGTTG |
ACCACGGTGG |
|
| 1281 |
AGGAGCTGTG |
TGACCAGAAC |
GAGTTCCACG |
GGTCTCAGGA |
GAGATACTTT |
GAACTGGTGG |
AGAGATGTGC |
GGACCAGAGG |
|
| 1361 |
CCTGAGTCCT |
CCCTCCTGAA |
CCTGATCTCC |
TATAGAGCGC |
AGTCCATCCA |
CCCGGCCAAG |
GACGGCTGGA |
TTCAGAACCT |
|
| 1441 |
GCAGGCGCTG |
ATGGAGAGAT |
TCTTCAGGAG |
CGAGTCCCGA |
GGCGCCGTGC |
GCATCAAGGT |
GCTGGACGTG |
CTGTCCTTTG |
|
| 1521 |
TGCTGCTCAT |
CAACAGGCAG |
TTCTATGAGG |
AGGAGCTGAT |
TAACTCAGTG |
GTCATCTCGC |
AGCTCTCCCA |
CATCCCCGAG |
|
| 1601 |
GATAAAGACC |
ACCAGGTCCG |
AAAGCTGGCC |
ACCCAGTTGC |
TGGTGGACCT |
GGCAGAGGGC |
TGCCACACAC |
ACCACTTCAA |
|
| 1681 |
CAGCCTGCTG |
GACATCATCG |
AGAAGGTGAT |
GGCCCGCTCC |
CTCTCCCCAC |
CCCCGGAGCT |
GGAAGAAAGG |
GATGTGGCCG |
|
| 1761 |
CATACTCGGC |
CTCCTTGGAG |
GATGTGAAGA |
CAGCCGTCCT |
GGGGCTTCTG |
GTCATCCTTC |
AGACCAAGCT |
GTACACCCTG |
|
| 1841 |
CCTGCAAGCC |
ACGCCACGCG |
TGTGTATGAG |
ATGCTGGTCA |
GCCACATTCA |
GCTCCACTAC |
AAGCACAGCT |
ACACCCTGCC |
|
| 1921 |
AATCGCGAGC |
AGCATCCGGC |
TGCAGGCCTT |
TGACTTCCTG |
TTGCTGCTGC |
GGGCCGACTC |
ACTGCACCGC |
CTGGGCCTGC |
|
| 2001 |
CCAACAAGGA |
TGGAGTCGTG |
CGGTTCAGCC |
CCTACTGCGT |
CTGCGACTAC |
ATGGAGCCAG |
AGAGAGGCTC |
TGAGAAGAAG |
|
| 2081 |
ACCAGCGGCC |
CCCTTTCTCC |
TCCCACAGGG |
CCTCCTGGCC |
CGGCGCCTGC |
AGGCCCCGCC |
GTGCGGCTGG |
GGTCCGTGCC |
|
| 2161 |
CTACTCCCTG |
CTCTTCCGCG |
TCCTGCTGCA |
GTGCTTGAAG |
CAGGAGTCTG |
ACTGGAAGGT |
GCTGAAGCTG |
GTTCTGGGCA |
|
| 2241 |
GGCTGCCTGA |
GTCCCTGCGC |
TATAAAGTGC |
TCATCTTTAC |
TTCCCCTTGC |
AGTGTGGACC |
AGCTGTGCTC |
TGCTCTCTGC |
|
| 2321 |
TCCATGCTTT |
CAGGCCCAAA |
GACACTGGAG |
CGGCTCCGAG |
GCGCCCCAGA |
AGGCTTCTCC |
AGAACTGACT |
TGCACCTGGC |
|
| 2401 |
CGTGGTTCCA |
GTGCTGACAG |
CATTAATCTC |
TTACCATAAC |
TACCTGGACA |
AAACCAAACA |
GCGCGAGATG |
GTCTACTGCC |
|
| 2481 |
TGGAGCAGGG |
CCTCATCCAC |
CGCTGTGCCA |
GCCAGTGCGT |
CGTGGCCTTG |
TCCATCTGCA |
GCGTGGAGAT |
GCCTGACATC |
|
| 2561 |
ATCATCAAGG |
CGCTGCCTGT |
TCTGGTGGTG |
AAGCTCACGC |
ACATCTCAGC |
CACAGCCAGC |
ATGGCCGTCC |
CACTGCTGGA |
|
| 2641 |
GTTCCTGTCC |
ACTCTGGCCA |
GGCTGCCGCA |
CCTCTACAGG |
AACTTTGCCG |
CGGAGCAGTA |
TGCCAGTGTG |
TTCGCCATCT |
|
| 2721 |
CCCTGCCGTA |
CACCAACCCC |
TCCAAGTTTA |
ATCAGTACAT |
CGTGTGTCTG |
GCCCATCACG |
TCATAGCCAT |
GTGGTTCATC |
|
| 2801 |
AGGTGCCGCC |
TGCCCTTCCG |
GAAGGATTTT |
GTCCCTTTCA |
TCACTAAGGG |
CCTGCGGTCC |
AATGTCCTCT |
TGTCTTTTGA |
|
| 2881 |
TGACACCCCC |
GAGAAGGACA |
GCTTCAGGGC |
CCGGAGTACT |
AGTCTCAACG |
AGAGACCCAA |
GAGGATACAG |
ACGTCCCTCA |
|
| 2961 |
CCAGTGCCAG |
CTTGGGGTCT |
GCAGATGAGA |
ACTCCGTGGC |
CCAGGCTGAC |
GATAGCCTGA |
AAAACCTCCA |
CCTGGAGCTC |
|
| 3041 |
ACGGAAACCT |
GTCTGGACAT |
GATGGCTCGA |
TACGTCTTCT |
CCAACTTCAC |
GGCTGTCCCG |
AAGAGGTCTC |
CTGTGGGCGA |
|
| 3121 |
GTTCCTCCTA |
GCGGGTGGCA |
GGACCAAAAC |
CTGGCTGGTT |
GGGAACAAGC |
TTGTCACTGT |
GACGACAAGC |
GTGGGAACCG |
|
| 3201 |
GGACCCGGTC |
GTTACTAGGC |
CTGGACTCGG |
GGGAGCTGCA |
GTCCGGCCCG |
GAGTCGAGCT |
CCAGCCCCGG |
GGTGCATGTG |
|
| 3281 |
AGACAGACCA |
AGGAGGCGCC |
GGCCAAGCTG |
GAGTCCCAGG |
CTGGGCAGCA |
GGTGTCCCGT |
GGGGCCCGGG |
ATCGGGTCCG |
|
| 3361 |
TTCCATGTCG |
GGGGGCCATG |
GTCTTCGAGT |
TGGCGCCCTG |
GACGTGCCGG |
CCTCCCAGTT |
CCTGGGCAGT |
GCCACTTCTC |
|
| 3441 |
CAGGACCACG |
GACTGCACCA |
GCCGCGAAAC |
CTGAGAAGGC |
CTCAGCTGGC |
ACCCGGGTTC |
CTGTGCAGGA |
GAAGACGAAC |
|
| 3521 |
CTGGCGGCCT |
ATGTGCCCCT |
GCTGACCCAG |
GGCTGGGCGG |
AGATCCTGGT |
CCGGAGGCCC |
ACAGGGAACA |
CCAGCTGGCT |
|
| 3601 |
GATGAGCCTG |
GAGAACCCGC |
TCAGCCCTTT |
CTCCTCGGAC |
ATCAACAACA |
TGCCCCTGCA |
GGAGCTGTCT |
AACGCCCTCA |
|
| 3681 |
TGGCGGCTGA |
GCGCTTCAAG |
GAGCACCGGG |
ACACAGCCCT |
GTACAAGTCA |
CTGTCGGTGC |
CGGCAGCCAG |
CACGGCCAAA |
|
| 3761 |
CCCCCTCCTC |
TGCCTCGCTC |
CAACACAGAC |
TCCGCCGTGG |
TCATGGAGGA |
GGGAAGTCCG |
GGCGAGGTTC |
CTGTGCTGGT |
|
| 3841 |
GGAGCCCCCA |
GGGTTGGAGG |
ACGTTGAGGC |
AGCGCTAGGC |
ATGGACAGGC |
GCACGGATGC |
CTACAGCAGG |
TCGTCCTCAG |
|
| 3921 |
TCTCCAGCCA |
GGAGGAGAAG |
TCGCTCCACG |
CGGAGGAGCT |
GGTTGGCAGG |
GGCATCCCCA |
TCGAGCGAGT |
CGTCTCCTCG |
|
| 4001 |
GAGGGTGGCC |
GGCCCTCTGT |
GGACCTCTCC |
TTCCAGCCCT |
CGCAGCCCCT |
GAGCAAGTCC |
AGCTCCTCTC |
CCGAGCTGCA |
|
| 4081 |
GACTCTGCAG |
GACATCCTCG |
GGGACCCTGG |
GGACAAGGCC |
GACGTGGGCC |
GGCTGAGCCC |
TGAGGTTAAG |
GCCCGGTCAC |
|
| 4161 |
AGTCAGGGAC |
CCTGGACGGG |
GAAAGTGCTG |
CCTGGTCGGC |
CTCGGGCGAA |
GACAGTCGGG |
GCCAGCCCGA |
GGGTCCCTTG |
|
| 4241 |
CCTTCCAGCT |
CCCCCCGCTC |
GCCCAGTGGC |
CTCCGGCCCC |
GAGGTTACAC |
CATCTCCGAC |
TCGGCCCCAT |
CACGCAGGGG |
|
| 4321 |
CAAGAGAGTA |
GAGAGGGACG |
CCTTAAAGAG |
CAGAGCCACA |
GCCTCCAATG |
CAGAGAAAGT |
GCCAGGCATC |
AACCCCAGTT |
|
| 4401 |
TCGTGTTCCT |
GCAGCTCTAC |
CATTCCCCCT |
TCTTTGGCGA |
CGAGTCAAAC |
AAGCCAATCC |
TGCTGCCCAA |
TGAGTCACAG |
|
| 4481 |
TCCTTTGAGC |
GGTCGGTGCA |
GCTCCTCGAC |
CAGATCCCAT |
CATACGACAC |
CCACAAGATC |
GCCGTCCTGT |
ATGTTGGAGA |
|
| 4561 |
AGGCCAGAGC |
AACAGCGAGC |
TCGCCATCCT |
GTCCAATGAG |
CATGGCTCCT |
ACAGGTACAC |
GGAGTTCCTG |
ACGGGCCTGG |
|
| 4641 |
GCCGGCTCAT |
CGAGCTGAAG |
GACTGCCAGC |
CGGACAAGGT |
GTACCTGGGA |
GGCCTGGACG |
TGTGTGGTGA |
GGACGGCCAG |
|
| 4721 |
TTCACCTACT |
GCTGGCACGA |
TGACATCATG |
CAAGCCGTCT |
TCCACATCGC |
CACCCTGATG |
CCCACCAAGG |
ACGTGGACAA |
|
| 4801 |
GCACCGCTGC |
GACAAGAAGC |
GCCACCTGGG |
CAACGACTTT |
GTGTCCATTG |
TCTACAATGA |
CTCCGGTGAG |
GACTTCAAGC |
|
| 4881 |
TTGGCACCAT |
CAAGGGCCAG |
TTCAACTTTG |
TCCACGTGAT |
CGTCACCCCG |
CTGGACTACG |
AGTGCAACCT |
GGTGTCCCTG |
|
| 4961 |
CAGTGCAGGA |
AAGACATGGA |
GGGCCTTGTG |
GACACCAGCG |
TGGCCAAGAT |
CGTGTCTGAC |
CGCAACCTGC |
CCTTCGTGGC |
|
| 5041 |
CCGCCAGATG |
GCCCTGCACG |
CAAATATGGC |
CTCACAGGTG |
CATCATAGCC |
GCTCCAACCC |
CACCGATATC |
TACCCCTCCA |
|
| 5121 |
AGTGGATTGC |
CCGGCTCCGC |
CACATCAAGC |
GGCTCCGCCA |
GCGGATCTGC |
GAGGAAGCCG |
CCTACTCCAA |
CCCCAGCCTA |
|
| 5201 |
CCTCTGGTGC |
ACCCTCCGTC |
CCATAGCAAA |
GCCCCTGCAC |
AGACTCCAGC |
CGAGCCCACA |
CCTGGCTATG |
AGGTGGGCCA |
|
| 5281 |
GCGGAAGCGC |
CTCATCTCCT |
CGGTGGAGGA |
CTTCACCGAG |
TTTGTGTGAG |
GCCGGGGCCC |
TCCCTCCTGC |
ACTGGCCTTG |
|
| 5361 |
GACGGTATTG |
CCTGTCAGTG |
AAATAAATAA |
AGTCCTGACC |
CCAGTGCACA |
GACATAGAGG |
CACAGATTGC |
AAAAAAAAAA |
|
| 5441 |
AAAAAAAAAA |
AAAAAAAAAA |
AAAAAAAAAA |
AAAA |
|
|
|
|
|
|
|
|
|
|
|
|
>gi|116256349|ref|NM_001077183.1|Tuberous sclerosis 2 (TSC2), transcript variant 4
CCGGCGGCGTCCCGGGGCCAGGGGGGTGCGCCTTTCTCCGCGTCGGGGCGGCCCGGAGCGCGGTGGCGCGGCGCGGGAGG
GGTTTTCTGGTGCGTCCTGGTCCACCATGGCCAAACCAACAAGCAAAGATTCAGGCTTGAAGGAGAAGTTTAAGATTCTG
TTGGGACTGGGAACACCGAGGCCAAATCCCAGGTCTGCAGAGGGTAAACAGACGGAGTTTATCATCACCGCGGAAATACT
GAGAGAACTGAGCATGGAATGTGGCCTCAACAATCGCATCCGGATGATAGGGCAGATTTGTGAAGTCGCAAAAACCAAGA
AATTTGAAGAGCACGCAGTGGAAGCACTCTGGAAGGCGGTCGCGGATCTGTTGCAGCCGGAGCGGCCGCTGGAGGCCCGG
CACGCGGTGCTGGCTCTGCTGAAGGCCATCGTGCAGGGGCAGGGCGAGCGTTTGGGGGTCCTCAGAGCCCTCTTCTTTAA
GGTCATCAAGGATTACCCTTCCAACGAAGACCTTCACGAAAGGCTGGAGGTTTTCAAGGCCCTCACAGACAATGGGAGAC
ACATCACCTACTTGGAGGAAGAGCTGGCTGACTTTGTCCTGCAGTGGATGGATGTTGGCTTGTCCTCGGAATTCCTTCTG
GTGCTGGTGAACTTGGTCAAATTCAATAGCTGTTACCTCGACGAGTACATCGCAAGGATGGTTCAGATGATCTGTCTGCT
GTGCGTCCGGACCGCGTCCTCTGTGGACATAGAGGTCTCCCTGCAGGTGCTGGACGCCGTGGTCTGCTACAACTGCCTGC
CGGCTGAGAGCCTCCCGCTGTTCATCGTTACCCTCTGTCGCACCATCAACGTCAAGGAGCTCTGCGAGCCTTGCTGGAAG
CTGATGCGGAACCTCCTTGGCACCCACCTGGGCCACAGCGCCATCTACAACATGTGCCACCTCATGGAGGACAGAGCCTA
CATGGAGGACGCGCCCCTGCTGAGAGGAGCCGTGTTTTTTGTGGGCATGGCTCTCTGGGGAGCCCACCGGCTCTATTCTC
TCAGGAACTCGCCGACATCTGTGTTGCCATCATTTTACCAGGCCATGGCATGTCCGAACGAGGTGGTGTCCTATGAGATC
GTCCTGTCCATCACCAGGCTCATCAAGAAGTATAGGAAGGAGCTCCAGGTGGTGGCGTGGGACATTCTGCTGAACATCAT
CGAACGGCTCCTTCAGCAGCTCCAGACCTTGGACAGCCCGGAGCTCAGGACCATCGTCCATGACCTGTTGACCACGGTGG
AGGAGCTGTGTGACCAGAACGAGTTCCACGGGTCTCAGGAGAGATACTTTGAACTGGTGGAGAGATGTGCGGACCAGAGG
CCTGAGTCCTCCCTCCTGAACCTGATCTCCTATAGAGCGCAGTCCATCCACCCGGCCAAGGACGGCTGGATTCAGAACCT
GCAGGCGCTGATGGAGAGATTCTTCAGGAGCGAGTCCCGAGGCGCCGTGCGCATCAAGGTGCTGGACGTGCTGTCCTTTG
TGCTGCTCATCAACAGGCAGTTCTATGAGGAGGAGCTGATTAACTCAGTGGTCATCTCGCAGCTCTCCCACATCCCCGAG
GATAAAGACCACCAGGTCCGAAAGCTGGCCACCCAGTTGCTGGTGGACCTGGCAGAGGGCTGCCACACACACCACTTCAA
CAGCCTGCTGGACATCATCGAGAAGGTGATGGCCCGCTCCCTCTCCCCACCCCCGGAGCTGGAAGAAAGGGATGTGGCCG
CATACTCGGCCTCCTTGGAGGATGTGAAGACAGCCGTCCTGGGGCTTCTGGTCATCCTTCAGACCAAGCTGTACACCCTG
CCTGCAAGCCACGCCACGCGTGTGTATGAGATGCTGGTCAGCCACATTCAGCTCCACTACAAGCACAGCTACACCCTGCC
AATCGCGAGCAGCATCCGGCTGCAGGCCTTTGACTTCCTGTTGCTGCTGCGGGCCGACTCACTGCACCGCCTGGGCCTGC
CCAACAAGGATGGAGTCGTGCGGTTCAGCCCCTACTGCGTCTGCGACTACATGGAGCCAGAGAGAGGCTCTGAGAAGAAG
ACCAGCGGCCCCCTTTCTCCTCCCACAGGGCCTCCTGGCCCGGCGCCTGCAGGCCCCGCCGTGCGGCTGGGGTCCGTGCC
CTACTCCCTGCTCTTCCGCGTCCTGCTGCAGTGCTTGAAGCAGGAGTCTGACTGGAAGGTGCTGAAGCTGGTTCTGGGCA
GGCTGCCTGAGTCCCTGCGCTATAAAGTGCTCATCTTTACTTCCCCTTGCAGTGTGGACCAGCTGTGCTCTGCTCTCTGC
TCCATGCTTTCAGGCCCAAAGACACTGGAGCGGCTCCGAGGCGCCCCAGAAGGCTTCTCCAGAACTGACTTGCACCTGGC
CGTGGTTCCAGTGCTGACAGCATTAATCTCTTACCATAACTACCTGGACAAAACCAAACAGCGCGAGATGGTCTACTGCC
TGGAGCAGGGCCTCATCCACCGCTGTGCCAGCCAGTGCGTCGTGGCCTTGTCCATCTGCAGCGTGGAGATGCCTGACATC
ATCATCAAGGCGCTGCCTGTTCTGGTGGTGAAGCTCACGCACATCTCAGCCACAGCCAGCATGGCCGTCCCACTGCTGGA
GTTCCTGTCCACTCTGGCCAGGCTGCCGCACCTCTACAGGAACTTTGCCGCGGAGCAGTATGCCAGTGTGTTCGCCATCT
CCCTGCCGTACACCAACCCCTCCAAGTTTAATCAGTACATCGTGTGTCTGGCCCATCACGTCATAGCCATGTGGTTCATC
AGGTGCCGCCTGCCCTTCCGGAAGGATTTTGTCCCTTTCATCACTAAGGGCCTGCGGTCCAATGTCCTCTTGTCTTTTGA
TGACACCCCCGAGAAGGACAGCTTCAGGGCCCGGAGTACTAGTCTCAACGAGAGACCCAAGAGGATACAGACGTCCCTCA
CCAGTGCCAGCTTGGGGTCTGCAGATGAGAACTCCGTGGCCCAGGCTGACGATAGCCTGAAAAACCTCCACCTGGAGCTC
ACGGAAACCTGTCTGGACATGATGGCTCGATACGTCTTCTCCAACTTCACGGCTGTCCCGAAGAGGTCTCCTGTGGGCGA
GTTCCTCCTAGCGGGTGGCAGGACCAAAACCTGGCTGGTTGGGAACAAGCTTGTCACTGTGACGACAAGCGTGGGAACCG
GGACCCGGTCGTTACTAGGCCTGGACTCGGGGGAGCTGCAGTCCGGCCCGGAGTCGAGCTCCAGCCCCGGGGTGCATGTG
AGACAGACCAAGGAGGCGCCGGCCAAGCTGGAGTCCCAGGCTGGGCAGCAGGTGTCCCGTGGGGCCCGGGATCGGGTCCG
TTCCATGTCGGGGGGCCATGGTCTTCGAGTTGGCGCCCTGGACGTGCCGGCCTCCCAGTTCCTGGGCAGTGCCACTTCTC
CAGGACCACGGACTGCACCAGCCGCGAAACCTGAGAAGGCCTCAGCTGGCACCCGGGTTCCTGTGCAGGAGAAGACGAAC
CTGGCGGCCTATGTGCCCCTGCTGACCCAGGGCTGGGCGGAGATCCTGGTCCGGAGGCCCACAGGGAACACCAGCTGGCT
GATGAGCCTGGAGAACCCGCTCAGCCCTTTCTCCTCGGACATCAACAACATGCCCCTGCAGGAGCTGTCTAACGCCCTCA
TGGCGGCTGAGCGCTTCAAGGAGCACCGGGACACAGCCCTGTACAAGTCACTGTCGGTGCCGGCAGCCAGCACGGCCAAA
CCCCCTCCTCTGCCTCGCTCCAACACAGACTCCGCCGTGGTCATGGAGGAGGGAAGTCCGGGCGAGGTTCCTGTGCTGGT
GGAGCCCCCAGGGTTGGAGGACGTTGAGGCAGCGCTAGGCATGGACAGGCGCACGGATGCCTACAGCAGGTCGTCCTCAG
TCTCCAGCCAGGAGGAGAAGTCGCTCCACGCGGAGGAGCTGGTTGGCAGGGGCATCCCCATCGAGCGAGTCGTCTCCTCG
GAGGGTGGCCGGCCCTCTGTGGACCTCTCCTTCCAGCCCTCGCAGCCCCTGAGCAAGTCCAGCTCCTCTCCCGAGCTGCA
GACTCTGCAGGACATCCTCGGGGACCCTGGGGACAAGGCCGACGTGGGCCGGCTGAGCCCTGAGGTTAAGGCCCGGTCAC
AGTCAGGGACCCTGGACGGGGAAAGTGCTGCCTGGTCGGCCTCGGGCGAAGACAGTCGGGGCCAGCCCGAGGGTCCCTTG
CCTTCCAGCTCCCCCCGCTCGCCCAGTGGCCTCCGGCCCCGAGGTTACACCATCTCCGACTCGGCCCCATCACGCAGGGG
CAAGAGAGTAGAGAGGGACGCCTTAAAGAGCAGAGCCACAGCCTCCAATGCAGAGAAAGTGCCAGGCATCAACCCCAGTT
TCGTGTTCCTGCAGCTCTACCATTCCCCCTTCTTTGGCGACGAGTCAAACAAGCCAATCCTGCTGCCCAATGAGTCACAG
TCCTTTGAGCGGTCGGTGCAGCTCCTCGACCAGATCCCATCATACGACACCCACAAGATCGCCGTCCTGTATGTTGGAGA
AGGCCAGAGCAACAGCGAGCTCGCCATCCTGTCCAATGAGCATGGCTCCTACAGGTACACGGAGTTCCTGACGGGCCTGG
GCCGGCTCATCGAGCTGAAGGACTGCCAGCCGGACAAGGTGTACCTGGGAGGCCTGGACGTGTGTGGTGAGGACGGCCAG
TTCACCTACTGCTGGCACGATGACATCATGCAAGCCGTCTTCCACATCGCCACCCTGATGCCCACCAAGGACGTGGACAA
GCACCGCTGCGACAAGAAGCGCCACCTGGGCAACGACTTTGTGTCCATTGTCTACAATGACTCCGGTGAGGACTTCAAGC
TTGGCACCATCAAGGGCCAGTTCAACTTTGTCCACGTGATCGTCACCCCGCTGGACTACGAGTGCAACCTGGTGTCCCTG
CAGTGCAGGAAAGACATGGAGGGCCTTGTGGACACCAGCGTGGCCAAGATCGTGTCTGACCGCAACCTGCCCTTCGTGGC
CCGCCAGATGGCCCTGCACGCAAATATGGCCTCACAGGTGCATCATAGCCGCTCCAACCCCACCGATATCTACCCCTCCA
AGTGGATTGCCCGGCTCCGCCACATCAAGCGGCTCCGCCAGCGGATCTGCGAGGAAGCCGCCTACTCCAACCCCAGCCTA
CCTCTGGTGCACCCTCCGTCCCATAGCAAAGCCCCTGCACAGACTCCAGCCGAGCCCACACCTGGCTATGAGGTGGGCCA
GCGGAAGCGCCTCATCTCCTCGGTGGAGGACTTCACCGAGTTTGTGTGAGGCCGGGGCCCTCCCTCCTGCACTGGCCTTG
GACGGTATTGCCTGTCAGTGAAATAAATAAAGTCCTGACCCCAGTGCACAGACATAGAGGCACAGATTGCAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
|
|
|
| |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Primary source |
RefSeq : NM_001114382.1 (GI:167412123)
|
| Name |
Tuberous sclerosis 2 (TSC2), transcript variant 5
|
| Type of transcript |
mRNA
|
| Organism |
Homo sapiens
|
| Length |
5577 nt
|
| Map |
16p13.3
|
| Location |
Chromosome 16 (NC_000016.9) strand : +
| 2097989...2098065 | 2098587...2098753 | 2100400...2100486 | 2103342...2103452 |
| 2104296...2104440 | 2105402...2105519 | 2106196...2106244 | 2106644...2106769 |
| 2107105...2107178 | 2108747...2108873 | 2110670...2110813 | 2111871...2112008 |
| 2112497...2112600 | 2112972...2113053 | 2114272...2114427 | 2115519...2115635 |
| 2120456...2120578 | 2121510...2121616 | 2121784...2121934 | 2122241...2122363 |
| 2122849...2122983 | 2124200...2124389 | 2125799...2125892 | 2126068...2126170 |
| 2126491...2126585 | 2127598...2127726 | 2129032...2129196 | 2129276...2129428 |
| 2129557...2129669 | 2130165...2130377 | 2131595...2131798 | 2133695...2133816 |
| 2134228...2134715 | 2134951...2135026 | 2135230...2135322 | 2136193...2136379 |
| 2136732...2136871 | 2137863...2137941 | 2138048...2138139 | 2138227...2138325 |
| 2138446...2138712 |
|
|
|
|
|
|
|
|
|
|
|
|
|
| Exon(s) |
Start |
End |
Length |
is coding |
|
Exon 1
|
1
|
77
|
77
|
1
|
|
Exon 2
|
78
|
244
|
167
|
1
|
|
Exon 3
|
245
|
331
|
87
|
1
|
|
Exon 4
|
332
|
442
|
111
|
1
|
|
Exon 5
|
443
|
587
|
145
|
1
|
|
Exon 6
|
588
|
705
|
118
|
1
|
|
Exon 7
|
706
|
754
|
49
|
1
|
|
Exon 8
|
755
|
880
|
126
|
1
|
|
Exon 9
|
881
|
954
|
74
|
1
|
|
Exon 10
|
955
|
1081
|
127
|
1
|
|
Exon 11
|
1082
|
1225
|
144
|
1
|
|
Exon 12
|
1226
|
1363
|
138
|
1
|
|
Exon 13
|
1364
|
1467
|
104
|
1
|
|
Exon 14
|
1468
|
1549
|
82
|
1
|
|
Exon 15
|
1550
|
1705
|
156
|
1
|
|
Exon 16
|
1706
|
1822
|
117
|
1
|
|
Exon 17
|
1823
|
1945
|
123
|
1
|
|
Exon 18
|
1946
|
2052
|
107
|
1
|
|
Exon 19
|
2053
|
2203
|
151
|
1
|
|
Exon 20
|
2204
|
2326
|
123
|
1
|
|
Exon 21
|
2327
|
2461
|
135
|
1
|
|
Exon 22
|
2462
|
2651
|
190
|
1
|
|
Exon 23
|
2652
|
2745
|
94
|
1
|
|
Exon 24
|
2746
|
2848
|
103
|
1
|
|
Exon 25
|
2849
|
2943
|
95
|
1
|
|
Exon 26
|
2944
|
3072
|
129
|
1
|
|
Exon 27a
|
3073
|
3237
|
165
|
1
|
|
Exon 28
|
3238
|
3390
|
153
|
1
|
|
Exon 29
|
3391
|
3503
|
113
|
1
|
|
Exon 30
|
3504
|
3716
|
213
|
1
|
|
Exon 31
|
3717
|
3920
|
204
|
1
|
|
Exon 33
|
3921
|
4042
|
122
|
1
|
|
Exon 34
|
4043
|
4530
|
488
|
1
|
|
Exon 35
|
4531
|
4606
|
76
|
1
|
|
Exon 36
|
4607
|
4699
|
93
|
1
|
|
Exon 37
|
4700
|
4886
|
187
|
1
|
|
Exon 38
|
4887
|
5026
|
140
|
1
|
|
Exon 39
|
5027
|
5105
|
79
|
1
|
|
Exon 40
|
5106
|
5197
|
92
|
1
|
|
Exon 41
|
5198
|
5296
|
99
|
1
|
|
Exon 42
|
5297
|
5563
|
267
|
1
|
|
|
|
|
|
|
|
|
|
|
|
|
| ID |
Class |
Location |
Mutation |
Length |
is synonymous |
Source |
|
|
|
|
|
|
|
|
|
|
|
|
| Primary source |
NCBI : CCDS45384
|
| Nucleotide |
TSC2, mRNA isoform 5[NM_001114382.1] : 107...5461
|
| Length |
5355
|
| Location |
Chromosome 16 (NC_000016.9) strand : +
| 2098616...2098753 | 2100400...2100486 | 2103342...2103452 | 2104296...2104440 |
| 2105402...2105519 | 2106196...2106244 | 2106644...2106769 | 2107105...2107178 |
| 2108747...2108873 | 2110670...2110813 | 2111871...2112008 | 2112497...2112600 |
| 2112972...2113053 | 2114272...2114427 | 2115519...2115635 | 2120456...2120578 |
| 2121510...2121616 | 2121784...2121934 | 2122241...2122363 | 2122849...2122983 |
| 2124200...2124389 | 2125799...2125892 | 2126068...2126170 | 2126491...2126585 |
| 2127598...2127726 | 2129032...2129196 | 2129276...2129428 | 2129557...2129669 |
| 2130165...2130377 | 2131595...2131798 | 2133695...2133816 | 2134228...2134715 |
| 2134951...2135026 | 2135230...2135322 | 2136193...2136379 | 2136732...2136871 |
| 2137863...2137941 | 2138048...2138139 | 2138227...2138325 | 2138446...2138610 |
|
| Start codon |
1
|
| Translation |
NP_001107854.1 |
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
CCGGCGGCGT |
CCCGGGGCCA |
GGGGGGTGCG |
CCTTTCTCCG |
CGTCGGGGCG |
GCCCGGAGCG |
CGGTGGCGCG |
GCGCGGGAGG |
|
| 81 |
GGTTTTCTGG |
TGCGTCCTGG |
TCCACCATGG |
CCAAACCAAC |
AAGCAAAGAT |
TCAGGCTTGA |
AGGAGAAGTT |
TAAGATTCTG |
|
| 161 |
TTGGGACTGG |
GAACACCGAG |
GCCAAATCCC |
AGGTCTGCAG |
AGGGTAAACA |
GACGGAGTTT |
ATCATCACCG |
CGGAAATACT |
|
| 241 |
GAGAGAACTG |
AGCATGGAAT |
GTGGCCTCAA |
CAATCGCATC |
CGGATGATAG |
GGCAGATTTG |
TGAAGTCGCA |
AAAACCAAGA |
|
| 321 |
AATTTGAAGA |
GCACGCAGTG |
GAAGCACTCT |
GGAAGGCGGT |
CGCGGATCTG |
TTGCAGCCGG |
AGCGGCCGCT |
GGAGGCCCGG |
|
| 401 |
CACGCGGTGC |
TGGCTCTGCT |
GAAGGCCATC |
GTGCAGGGGC |
AGGGCGAGCG |
TTTGGGGGTC |
CTCAGAGCCC |
TCTTCTTTAA |
|
| 481 |
GGTCATCAAG |
GATTACCCTT |
CCAACGAAGA |
CCTTCACGAA |
AGGCTGGAGG |
TTTTCAAGGC |
CCTCACAGAC |
AATGGGAGAC |
|
| 561 |
ACATCACCTA |
CTTGGAGGAA |
GAGCTGGCTG |
ACTTTGTCCT |
GCAGTGGATG |
GATGTTGGCT |
TGTCCTCGGA |
ATTCCTTCTG |
|
| 641 |
GTGCTGGTGA |
ACTTGGTCAA |
ATTCAATAGC |
TGTTACCTCG |
ACGAGTACAT |
CGCAAGGATG |
GTTCAGATGA |
TCTGTCTGCT |
|
| 721 |
GTGCGTCCGG |
ACCGCGTCCT |
CTGTGGACAT |
AGAGGTCTCC |
CTGCAGGTGC |
TGGACGCCGT |
GGTCTGCTAC |
AACTGCCTGC |
|
| 801 |
CGGCTGAGAG |
CCTCCCGCTG |
TTCATCGTTA |
CCCTCTGTCG |
CACCATCAAC |
GTCAAGGAGC |
TCTGCGAGCC |
TTGCTGGAAG |
|
| 881 |
CTGATGCGGA |
ACCTCCTTGG |
CACCCACCTG |
GGCCACAGCG |
CCATCTACAA |
CATGTGCCAC |
CTCATGGAGG |
ACAGAGCCTA |
|
| 961 |
CATGGAGGAC |
GCGCCCCTGC |
TGAGAGGAGC |
CGTGTTTTTT |
GTGGGCATGG |
CTCTCTGGGG |
AGCCCACCGG |
CTCTATTCTC |
|
| 1041 |
TCAGGAACTC |
GCCGACATCT |
GTGTTGCCAT |
CATTTTACCA |
GGCCATGGCA |
TGTCCGAACG |
AGGTGGTGTC |
CTATGAGATC |
|
| 1121 |
GTCCTGTCCA |
TCACCAGGCT |
CATCAAGAAG |
TATAGGAAGG |
AGCTCCAGGT |
GGTGGCGTGG |
GACATTCTGC |
TGAACATCAT |
|
| 1201 |
CGAACGGCTC |
CTTCAGCAGC |
TCCAGACCTT |
GGACAGCCCG |
GAGCTCAGGA |
CCATCGTCCA |
TGACCTGTTG |
ACCACGGTGG |
|
| 1281 |
AGGAGCTGTG |
TGACCAGAAC |
GAGTTCCACG |
GGTCTCAGGA |
GAGATACTTT |
GAACTGGTGG |
AGAGATGTGC |
GGACCAGAGG |
|
| 1361 |
CCTGAGTCCT |
CCCTCCTGAA |
CCTGATCTCC |
TATAGAGCGC |
AGTCCATCCA |
CCCGGCCAAG |
GACGGCTGGA |
TTCAGAACCT |
|
| 1441 |
GCAGGCGCTG |
ATGGAGAGAT |
TCTTCAGGAG |
CGAGTCCCGA |
GGCGCCGTGC |
GCATCAAGGT |
GCTGGACGTG |
CTGTCCTTTG |
|
| 1521 |
TGCTGCTCAT |
CAACAGGCAG |
TTCTATGAGG |
AGGAGCTGAT |
TAACTCAGTG |
GTCATCTCGC |
AGCTCTCCCA |
CATCCCCGAG |
|
| 1601 |
GATAAAGACC |
ACCAGGTCCG |
AAAGCTGGCC |
ACCCAGTTGC |
TGGTGGACCT |
GGCAGAGGGC |
TGCCACACAC |
ACCACTTCAA |
|
| 1681 |
CAGCCTGCTG |
GACATCATCG |
AGAAGGTGAT |
GGCCCGCTCC |
CTCTCCCCAC |
CCCCGGAGCT |
GGAAGAAAGG |
GATGTGGCCG |
|
| 1761 |
CATACTCGGC |
CTCCTTGGAG |
GATGTGAAGA |
CAGCCGTCCT |
GGGGCTTCTG |
GTCATCCTTC |
AGACCAAGCT |
GTACACCCTG |
|
| 1841 |
CCTGCAAGCC |
ACGCCACGCG |
TGTGTATGAG |
ATGCTGGTCA |
GCCACATTCA |
GCTCCACTAC |
AAGCACAGCT |
ACACCCTGCC |
|
| 1921 |
AATCGCGAGC |
AGCATCCGGC |
TGCAGGCCTT |
TGACTTCCTG |
TTGCTGCTGC |
GGGCCGACTC |
ACTGCACCGC |
CTGGGCCTGC |
|
| 2001 |
CCAACAAGGA |
TGGAGTCGTG |
CGGTTCAGCC |
CCTACTGCGT |
CTGCGACTAC |
ATGGAGCCAG |
AGAGAGGCTC |
TGAGAAGAAG |
|
| 2081 |
ACCAGCGGCC |
CCCTTTCTCC |
TCCCACAGGG |
CCTCCTGGCC |
CGGCGCCTGC |
AGGCCCCGCC |
GTGCGGCTGG |
GGTCCGTGCC |
|
| 2161 |
CTACTCCCTG |
CTCTTCCGCG |
TCCTGCTGCA |
GTGCTTGAAG |
CAGGAGTCTG |
ACTGGAAGGT |
GCTGAAGCTG |
GTTCTGGGCA |
|
| 2241 |
GGCTGCCTGA |
GTCCCTGCGC |
TATAAAGTGC |
TCATCTTTAC |
TTCCCCTTGC |
AGTGTGGACC |
AGCTGTGCTC |
TGCTCTCTGC |
|
| 2321 |
TCCATGCTTT |
CAGGCCCAAA |
GACACTGGAG |
CGGCTCCGAG |
GCGCCCCAGA |
AGGCTTCTCC |
AGAACTGACT |
TGCACCTGGC |
|
| 2401 |
CGTGGTTCCA |
GTGCTGACAG |
CATTAATCTC |
TTACCATAAC |
TACCTGGACA |
AAACCAAACA |
GCGCGAGATG |
GTCTACTGCC |
|
| 2481 |
TGGAGCAGGG |
CCTCATCCAC |
CGCTGTGCCA |
GCCAGTGCGT |
CGTGGCCTTG |
TCCATCTGCA |
GCGTGGAGAT |
GCCTGACATC |
|
| 2561 |
ATCATCAAGG |
CGCTGCCTGT |
TCTGGTGGTG |
AAGCTCACGC |
ACATCTCAGC |
CACAGCCAGC |
ATGGCCGTCC |
CACTGCTGGA |
|
| 2641 |
GTTCCTGTCC |
ACTCTGGCCA |
GGCTGCCGCA |
CCTCTACAGG |
AACTTTGCCG |
CGGAGCAGTA |
TGCCAGTGTG |
TTCGCCATCT |
|
| 2721 |
CCCTGCCGTA |
CACCAACCCC |
TCCAAGTTTA |
ATCAGTACAT |
CGTGTGTCTG |
GCCCATCACG |
TCATAGCCAT |
GTGGTTCATC |
|
| 2801 |
AGGTGCCGCC |
TGCCCTTCCG |
GAAGGATTTT |
GTCCCTTTCA |
TCACTAAGGG |
CCTGCGGTCC |
AATGTCCTCT |
TGTCTTTTGA |
|
| 2881 |
TGACACCCCC |
GAGAAGGACA |
GCTTCAGGGC |
CCGGAGTACT |
AGTCTCAACG |
AGAGACCCAA |
GAGTCTGAGG |
ATAGCCAGAC |
|
| 2961 |
CCCCCAAACA |
AGGCTTGAAT |
AACTCTCCAC |
CCGTGAAAGA |
ATTCAAGGAG |
AGCTCTGCAG |
CCGAGGCCTT |
CCGGTGCCGC |
|
| 3041 |
AGCATCAGTG |
TGTCTGAACA |
TGTGGTCCGC |
AGCAGGATAC |
AGACGTCCCT |
CACCAGTGCC |
AGCTTGGGGT |
CTGCAGATGA |
|
| 3121 |
GAACTCCGTG |
GCCCAGGCTG |
ACGATAGCCT |
GAAAAACCTC |
CACCTGGAGC |
TCACGGAAAC |
CTGTCTGGAC |
ATGATGGCTC |
|
| 3201 |
GATACGTCTT |
CTCCAACTTC |
ACGGCTGTCC |
CGAAGAGGTC |
TCCTGTGGGC |
GAGTTCCTCC |
TAGCGGGTGG |
CAGGACCAAA |
|
| 3281 |
ACCTGGCTGG |
TTGGGAACAA |
GCTTGTCACT |
GTGACGACAA |
GCGTGGGAAC |
CGGGACCCGG |
TCGTTACTAG |
GCCTGGACTC |
|
| 3361 |
GGGGGAGCTG |
CAGTCCGGCC |
CGGAGTCGAG |
CTCCAGCCCC |
GGGGTGCATG |
TGAGACAGAC |
CAAGGAGGCG |
CCGGCCAAGC |
|
| 3441 |
TGGAGTCCCA |
GGCTGGGCAG |
CAGGTGTCCC |
GTGGGGCCCG |
GGATCGGGTC |
CGTTCCATGT |
CGGGGGGCCA |
TGGTCTTCGA |
|
| 3521 |
GTTGGCGCCC |
TGGACGTGCC |
GGCCTCCCAG |
TTCCTGGGCA |
GTGCCACTTC |
TCCAGGACCA |
CGGACTGCAC |
CAGCCGCGAA |
|
| 3601 |
ACCTGAGAAG |
GCCTCAGCTG |
GCACCCGGGT |
TCCTGTGCAG |
GAGAAGACGA |
ACCTGGCGGC |
CTATGTGCCC |
CTGCTGACCC |
|
| 3681 |
AGGGCTGGGC |
GGAGATCCTG |
GTCCGGAGGC |
CCACAGGGAA |
CACCAGCTGG |
CTGATGAGCC |
TGGAGAACCC |
GCTCAGCCCT |
|
| 3761 |
TTCTCCTCGG |
ACATCAACAA |
CATGCCCCTG |
CAGGAGCTGT |
CTAACGCCCT |
CATGGCGGCT |
GAGCGCTTCA |
AGGAGCACCG |
|
| 3841 |
GGACACAGCC |
CTGTACAAGT |
CACTGTCGGT |
GCCGGCAGCC |
AGCACGGCCA |
AACCCCCTCC |
TCTGCCTCGC |
TCCAACACAG |
|
| 3921 |
ACTCCGCCGT |
GGTCATGGAG |
GAGGGAAGTC |
CGGGCGAGGT |
TCCTGTGCTG |
GTGGAGCCCC |
CAGGGTTGGA |
GGACGTTGAG |
|
| 4001 |
GCAGCGCTAG |
GCATGGACAG |
GCGCACGGAT |
GCCTACAGCA |
GGTCGTCCTC |
AGTCTCCAGC |
CAGGAGGAGA |
AGTCGCTCCA |
|
| 4081 |
CGCGGAGGAG |
CTGGTTGGCA |
GGGGCATCCC |
CATCGAGCGA |
GTCGTCTCCT |
CGGAGGGTGG |
CCGGCCCTCT |
GTGGACCTCT |
|
| 4161 |
CCTTCCAGCC |
CTCGCAGCCC |
CTGAGCAAGT |
CCAGCTCCTC |
TCCCGAGCTG |
CAGACTCTGC |
AGGACATCCT |
CGGGGACCCT |
|
| 4241 |
GGGGACAAGG |
CCGACGTGGG |
CCGGCTGAGC |
CCTGAGGTTA |
AGGCCCGGTC |
ACAGTCAGGG |
ACCCTGGACG |
GGGAAAGTGC |
|
| 4321 |
TGCCTGGTCG |
GCCTCGGGCG |
AAGACAGTCG |
GGGCCAGCCC |
GAGGGTCCCT |
TGCCTTCCAG |
CTCCCCCCGC |
TCGCCCAGTG |
|
| 4401 |
GCCTCCGGCC |
CCGAGGTTAC |
ACCATCTCCG |
ACTCGGCCCC |
ATCACGCAGG |
GGCAAGAGAG |
TAGAGAGGGA |
CGCCTTAAAG |
|
| 4481 |
AGCAGAGCCA |
CAGCCTCCAA |
TGCAGAGAAA |
GTGCCAGGCA |
TCAACCCCAG |
TTTCGTGTTC |
CTGCAGCTCT |
ACCATTCCCC |
|
| 4561 |
CTTCTTTGGC |
GACGAGTCAA |
ACAAGCCAAT |
CCTGCTGCCC |
AATGAGTCAC |
AGTCCTTTGA |
GCGGTCGGTG |
CAGCTCCTCG |
|
| 4641 |
ACCAGATCCC |
ATCATACGAC |
ACCCACAAGA |
TCGCCGTCCT |
GTATGTTGGA |
GAAGGCCAGA |
GCAACAGCGA |
GCTCGCCATC |
|
| 4721 |
CTGTCCAATG |
AGCATGGCTC |
CTACAGGTAC |
ACGGAGTTCC |
TGACGGGCCT |
GGGCCGGCTC |
ATCGAGCTGA |
AGGACTGCCA |
|
| 4801 |
GCCGGACAAG |
GTGTACCTGG |
GAGGCCTGGA |
CGTGTGTGGT |
GAGGACGGCC |
AGTTCACCTA |
CTGCTGGCAC |
GATGACATCA |
|
| 4881 |
TGCAAGCCGT |
CTTCCACATC |
GCCACCCTGA |
TGCCCACCAA |
GGACGTGGAC |
AAGCACCGCT |
GCGACAAGAA |
GCGCCACCTG |
|
| 4961 |
GGCAACGACT |
TTGTGTCCAT |
TGTCTACAAT |
GACTCCGGTG |
AGGACTTCAA |
GCTTGGCACC |
ATCAAGGGCC |
AGTTCAACTT |
|
| 5041 |
TGTCCACGTG |
ATCGTCACCC |
CGCTGGACTA |
CGAGTGCAAC |
CTGGTGTCCC |
TGCAGTGCAG |
GAAAGACATG |
GAGGGCCTTG |
|
| 5121 |
TGGACACCAG |
CGTGGCCAAG |
ATCGTGTCTG |
ACCGCAACCT |
GCCCTTCGTG |
GCCCGCCAGA |
TGGCCCTGCA |
CGCAAATATG |
|
| 5201 |
GCCTCACAGG |
TGCATCATAG |
CCGCTCCAAC |
CCCACCGATA |
TCTACCCCTC |
CAAGTGGATT |
GCCCGGCTCC |
GCCACATCAA |
|
| 5281 |
GCGGCTCCGC |
CAGCGGATCT |
GCGAGGAAGC |
CGCCTACTCC |
AACCCCAGCC |
TACCTCTGGT |
GCACCCTCCG |
TCCCATAGCA |
|
| 5361 |
AAGCCCCTGC |
ACAGACTCCA |
GCCGAGCCCA |
CACCTGGCTA |
TGAGGTGGGC |
CAGCGGAAGC |
GCCTCATCTC |
CTCGGTGGAG |
|
| 5441 |
GACTTCACCG |
AGTTTGTGTG |
AGGCCGGGGC |
CCTCCCTCCT |
GCACTGGCCT |
TGGACGGTAT |
TGCCTGTCAG |
TGAAATAAAT |
|
| 5521 |
AAAGTCCTGA |
CCCCAGTGCA |
CAGACATAGA |
GGCACAGATT |
GCAAAAAAAA |
AAAAAAA |
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>gi|167412123|ref|NM_001114382.1|Tuberous sclerosis 2 (TSC2), transcript variant 5
CCGGCGGCGTCCCGGGGCCAGGGGGGTGCGCCTTTCTCCGCGTCGGGGCGGCCCGGAGCGCGGTGGCGCGGCGCGGGAGG
GGTTTTCTGGTGCGTCCTGGTCCACCATGGCCAAACCAACAAGCAAAGATTCAGGCTTGAAGGAGAAGTTTAAGATTCTG
TTGGGACTGGGAACACCGAGGCCAAATCCCAGGTCTGCAGAGGGTAAACAGACGGAGTTTATCATCACCGCGGAAATACT
GAGAGAACTGAGCATGGAATGTGGCCTCAACAATCGCATCCGGATGATAGGGCAGATTTGTGAAGTCGCAAAAACCAAGA
AATTTGAAGAGCACGCAGTGGAAGCACTCTGGAAGGCGGTCGCGGATCTGTTGCAGCCGGAGCGGCCGCTGGAGGCCCGG
CACGCGGTGCTGGCTCTGCTGAAGGCCATCGTGCAGGGGCAGGGCGAGCGTTTGGGGGTCCTCAGAGCCCTCTTCTTTAA
GGTCATCAAGGATTACCCTTCCAACGAAGACCTTCACGAAAGGCTGGAGGTTTTCAAGGCCCTCACAGACAATGGGAGAC
ACATCACCTACTTGGAGGAAGAGCTGGCTGACTTTGTCCTGCAGTGGATGGATGTTGGCTTGTCCTCGGAATTCCTTCTG
GTGCTGGTGAACTTGGTCAAATTCAATAGCTGTTACCTCGACGAGTACATCGCAAGGATGGTTCAGATGATCTGTCTGCT
GTGCGTCCGGACCGCGTCCTCTGTGGACATAGAGGTCTCCCTGCAGGTGCTGGACGCCGTGGTCTGCTACAACTGCCTGC
CGGCTGAGAGCCTCCCGCTGTTCATCGTTACCCTCTGTCGCACCATCAACGTCAAGGAGCTCTGCGAGCCTTGCTGGAAG
CTGATGCGGAACCTCCTTGGCACCCACCTGGGCCACAGCGCCATCTACAACATGTGCCACCTCATGGAGGACAGAGCCTA
CATGGAGGACGCGCCCCTGCTGAGAGGAGCCGTGTTTTTTGTGGGCATGGCTCTCTGGGGAGCCCACCGGCTCTATTCTC
TCAGGAACTCGCCGACATCTGTGTTGCCATCATTTTACCAGGCCATGGCATGTCCGAACGAGGTGGTGTCCTATGAGATC
GTCCTGTCCATCACCAGGCTCATCAAGAAGTATAGGAAGGAGCTCCAGGTGGTGGCGTGGGACATTCTGCTGAACATCAT
CGAACGGCTCCTTCAGCAGCTCCAGACCTTGGACAGCCCGGAGCTCAGGACCATCGTCCATGACCTGTTGACCACGGTGG
AGGAGCTGTGTGACCAGAACGAGTTCCACGGGTCTCAGGAGAGATACTTTGAACTGGTGGAGAGATGTGCGGACCAGAGG
CCTGAGTCCTCCCTCCTGAACCTGATCTCCTATAGAGCGCAGTCCATCCACCCGGCCAAGGACGGCTGGATTCAGAACCT
GCAGGCGCTGATGGAGAGATTCTTCAGGAGCGAGTCCCGAGGCGCCGTGCGCATCAAGGTGCTGGACGTGCTGTCCTTTG
TGCTGCTCATCAACAGGCAGTTCTATGAGGAGGAGCTGATTAACTCAGTGGTCATCTCGCAGCTCTCCCACATCCCCGAG
GATAAAGACCACCAGGTCCGAAAGCTGGCCACCCAGTTGCTGGTGGACCTGGCAGAGGGCTGCCACACACACCACTTCAA
CAGCCTGCTGGACATCATCGAGAAGGTGATGGCCCGCTCCCTCTCCCCACCCCCGGAGCTGGAAGAAAGGGATGTGGCCG
CATACTCGGCCTCCTTGGAGGATGTGAAGACAGCCGTCCTGGGGCTTCTGGTCATCCTTCAGACCAAGCTGTACACCCTG
CCTGCAAGCCACGCCACGCGTGTGTATGAGATGCTGGTCAGCCACATTCAGCTCCACTACAAGCACAGCTACACCCTGCC
AATCGCGAGCAGCATCCGGCTGCAGGCCTTTGACTTCCTGTTGCTGCTGCGGGCCGACTCACTGCACCGCCTGGGCCTGC
CCAACAAGGATGGAGTCGTGCGGTTCAGCCCCTACTGCGTCTGCGACTACATGGAGCCAGAGAGAGGCTCTGAGAAGAAG
ACCAGCGGCCCCCTTTCTCCTCCCACAGGGCCTCCTGGCCCGGCGCCTGCAGGCCCCGCCGTGCGGCTGGGGTCCGTGCC
CTACTCCCTGCTCTTCCGCGTCCTGCTGCAGTGCTTGAAGCAGGAGTCTGACTGGAAGGTGCTGAAGCTGGTTCTGGGCA
GGCTGCCTGAGTCCCTGCGCTATAAAGTGCTCATCTTTACTTCCCCTTGCAGTGTGGACCAGCTGTGCTCTGCTCTCTGC
TCCATGCTTTCAGGCCCAAAGACACTGGAGCGGCTCCGAGGCGCCCCAGAAGGCTTCTCCAGAACTGACTTGCACCTGGC
CGTGGTTCCAGTGCTGACAGCATTAATCTCTTACCATAACTACCTGGACAAAACCAAACAGCGCGAGATGGTCTACTGCC
TGGAGCAGGGCCTCATCCACCGCTGTGCCAGCCAGTGCGTCGTGGCCTTGTCCATCTGCAGCGTGGAGATGCCTGACATC
ATCATCAAGGCGCTGCCTGTTCTGGTGGTGAAGCTCACGCACATCTCAGCCACAGCCAGCATGGCCGTCCCACTGCTGGA
GTTCCTGTCCACTCTGGCCAGGCTGCCGCACCTCTACAGGAACTTTGCCGCGGAGCAGTATGCCAGTGTGTTCGCCATCT
CCCTGCCGTACACCAACCCCTCCAAGTTTAATCAGTACATCGTGTGTCTGGCCCATCACGTCATAGCCATGTGGTTCATC
AGGTGCCGCCTGCCCTTCCGGAAGGATTTTGTCCCTTTCATCACTAAGGGCCTGCGGTCCAATGTCCTCTTGTCTTTTGA
TGACACCCCCGAGAAGGACAGCTTCAGGGCCCGGAGTACTAGTCTCAACGAGAGACCCAAGAGTCTGAGGATAGCCAGAC
CCCCCAAACAAGGCTTGAATAACTCTCCACCCGTGAAAGAATTCAAGGAGAGCTCTGCAGCCGAGGCCTTCCGGTGCCGC
AGCATCAGTGTGTCTGAACATGTGGTCCGCAGCAGGATACAGACGTCCCTCACCAGTGCCAGCTTGGGGTCTGCAGATGA
GAACTCCGTGGCCCAGGCTGACGATAGCCTGAAAAACCTCCACCTGGAGCTCACGGAAACCTGTCTGGACATGATGGCTC
GATACGTCTTCTCCAACTTCACGGCTGTCCCGAAGAGGTCTCCTGTGGGCGAGTTCCTCCTAGCGGGTGGCAGGACCAAA
ACCTGGCTGGTTGGGAACAAGCTTGTCACTGTGACGACAAGCGTGGGAACCGGGACCCGGTCGTTACTAGGCCTGGACTC
GGGGGAGCTGCAGTCCGGCCCGGAGTCGAGCTCCAGCCCCGGGGTGCATGTGAGACAGACCAAGGAGGCGCCGGCCAAGC
TGGAGTCCCAGGCTGGGCAGCAGGTGTCCCGTGGGGCCCGGGATCGGGTCCGTTCCATGTCGGGGGGCCATGGTCTTCGA
GTTGGCGCCCTGGACGTGCCGGCCTCCCAGTTCCTGGGCAGTGCCACTTCTCCAGGACCACGGACTGCACCAGCCGCGAA
ACCTGAGAAGGCCTCAGCTGGCACCCGGGTTCCTGTGCAGGAGAAGACGAACCTGGCGGCCTATGTGCCCCTGCTGACCC
AGGGCTGGGCGGAGATCCTGGTCCGGAGGCCCACAGGGAACACCAGCTGGCTGATGAGCCTGGAGAACCCGCTCAGCCCT
TTCTCCTCGGACATCAACAACATGCCCCTGCAGGAGCTGTCTAACGCCCTCATGGCGGCTGAGCGCTTCAAGGAGCACCG
GGACACAGCCCTGTACAAGTCACTGTCGGTGCCGGCAGCCAGCACGGCCAAACCCCCTCCTCTGCCTCGCTCCAACACAG
ACTCCGCCGTGGTCATGGAGGAGGGAAGTCCGGGCGAGGTTCCTGTGCTGGTGGAGCCCCCAGGGTTGGAGGACGTTGAG
GCAGCGCTAGGCATGGACAGGCGCACGGATGCCTACAGCAGGTCGTCCTCAGTCTCCAGCCAGGAGGAGAAGTCGCTCCA
CGCGGAGGAGCTGGTTGGCAGGGGCATCCCCATCGAGCGAGTCGTCTCCTCGGAGGGTGGCCGGCCCTCTGTGGACCTCT
CCTTCCAGCCCTCGCAGCCCCTGAGCAAGTCCAGCTCCTCTCCCGAGCTGCAGACTCTGCAGGACATCCTCGGGGACCCT
GGGGACAAGGCCGACGTGGGCCGGCTGAGCCCTGAGGTTAAGGCCCGGTCACAGTCAGGGACCCTGGACGGGGAAAGTGC
TGCCTGGTCGGCCTCGGGCGAAGACAGTCGGGGCCAGCCCGAGGGTCCCTTGCCTTCCAGCTCCCCCCGCTCGCCCAGTG
GCCTCCGGCCCCGAGGTTACACCATCTCCGACTCGGCCCCATCACGCAGGGGCAAGAGAGTAGAGAGGGACGCCTTAAAG
AGCAGAGCCACAGCCTCCAATGCAGAGAAAGTGCCAGGCATCAACCCCAGTTTCGTGTTCCTGCAGCTCTACCATTCCCC
CTTCTTTGGCGACGAGTCAAACAAGCCAATCCTGCTGCCCAATGAGTCACAGTCCTTTGAGCGGTCGGTGCAGCTCCTCG
ACCAGATCCCATCATACGACACCCACAAGATCGCCGTCCTGTATGTTGGAGAAGGCCAGAGCAACAGCGAGCTCGCCATC
CTGTCCAATGAGCATGGCTCCTACAGGTACACGGAGTTCCTGACGGGCCTGGGCCGGCTCATCGAGCTGAAGGACTGCCA
GCCGGACAAGGTGTACCTGGGAGGCCTGGACGTGTGTGGTGAGGACGGCCAGTTCACCTACTGCTGGCACGATGACATCA
TGCAAGCCGTCTTCCACATCGCCACCCTGATGCCCACCAAGGACGTGGACAAGCACCGCTGCGACAAGAAGCGCCACCTG
GGCAACGACTTTGTGTCCATTGTCTACAATGACTCCGGTGAGGACTTCAAGCTTGGCACCATCAAGGGCCAGTTCAACTT
TGTCCACGTGATCGTCACCCCGCTGGACTACGAGTGCAACCTGGTGTCCCTGCAGTGCAGGAAAGACATGGAGGGCCTTG
TGGACACCAGCGTGGCCAAGATCGTGTCTGACCGCAACCTGCCCTTCGTGGCCCGCCAGATGGCCCTGCACGCAAATATG
GCCTCACAGGTGCATCATAGCCGCTCCAACCCCACCGATATCTACCCCTCCAAGTGGATTGCCCGGCTCCGCCACATCAA
GCGGCTCCGCCAGCGGATCTGCGAGGAAGCCGCCTACTCCAACCCCAGCCTACCTCTGGTGCACCCTCCGTCCCATAGCA
AAGCCCCTGCACAGACTCCAGCCGAGCCCACACCTGGCTATGAGGTGGGCCAGCGGAAGCGCCTCATCTCCTCGGTGGAG
GACTTCACCGAGTTTGTGTGAGGCCGGGGCCCTCCCTCCTGCACTGGCCTTGGACGGTATTGCCTGTCAGTGAAATAAAT
AAAGTCCTGACCCCAGTGCACAGACATAGAGGCACAGATTGCAAAAAAAAAAAAAAA
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| Exon number |
27b
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| Length |
162 nt
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| Location |
Chromosome 16 (NC_000016.9) : 2129035...2129196 (+)
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| Is part of |
TSC2, mRNA isoform 4
(NM_001077183.1)
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| Sequence |
Show
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GATACAGACGTCCCTCACCAGTGCCAGCTTGGGGTCTGCAGATGAGAACTCCGTGGCCCAGGCTGACGATAGCCTGAAAA
ACCTCCACCTGGAGCTCACGGAAACCTGTCTGGACATGATGGCTCGATACGTCTTCTCCAACTTCACGGCTGTCCCGAAG
AG
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| Exon number |
34
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| Length |
488 nt
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| Location |
Chromosome 16 (NC_000016.9) : 2134228...2134715 (+)
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| Is part of |
TSC2, mRNA isoform 1
(NM_000548.3)
TSC2, mRNA isoform 5
(NM_001114382.1)
TSC2, mRNA isoform 4
(NM_001077183.1)
|
| Sequence |
Show
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TCGTCCTCAGTCTCCAGCCAGGAGGAGAAGTCGCTCCACGCGGAGGAGCTGGTTGGCAGGGGCATCCCCATCGAGCGAGT
CGTCTCCTCGGAGGGTGGCCGGCCCTCTGTGGACCTCTCCTTCCAGCCCTCGCAGCCCCTGAGCAAGTCCAGCTCCTCTC
CCGAGCTGCAGACTCTGCAGGACATCCTCGGGGACCCTGGGGACAAGGCCGACGTGGGCCGGCTGAGCCCTGAGGTTAAG
GCCCGGTCACAGTCAGGGACCCTGGACGGGGAAAGTGCTGCCTGGTCGGCCTCGGGCGAAGACAGTCGGGGCCAGCCCGA
GGGTCCCTTGCCTTCCAGCTCCCCCCGCTCGCCCAGTGGCCTCCGGCCCCGAGGTTACACCATCTCCGACTCGGCCCCAT
CACGCAGGGGCAAGAGAGTAGAGAGGGACGCCTTAAAGAGCAGAGCCACAGCCTCCAATGCAGAGAAAGTGCCAGGCATC
AACCCCAG
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| Primary source |
Uniprot : P49815
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| Name |
Tuberin
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| Alternative name(s) |
Tuberous sclerosis 2 protein
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| Synonym(s) |
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| Organism |
Homo sapiens
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| Length |
1807 aa
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| Protein existence |
---
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General annotation (Comments)
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top
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Disease
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Defects in TSC2 are the cause of tuberous sclerosis complex (TSC) [MIM:191100]. The molecular basis of TSC is a functional impairment of the tuberin-hamartin complex. TSC is an autosomal dominant multi-system disorder that affects especially the brain, kidneys, heart, and skin. TSC is characterized by hamartomas (benign overgrowths predominantly of a cell or tissue type that occurs normally in the organ) and hamartias (developmental abnormalities of tissue combination). Clinical symptoms can range from benign hypopigmented macules of the skin to profound mental retardation with intractable seizures to premature death from a variety of disease-associated causes.
Defects in TSC2 are a cause of lymphangioleiomyomatosis (LAM) [MIM:606690]. LAM is a progressive and often fatal lung disease characterized by a diffuse proliferation of abnormal smooth muscle cells in the lungs. It affects almost exclusively young women and can occur as an isolated disorder or in association with tuberous sclerosis complex.
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Function
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In complex with TSC1, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Acts as a GTPase- activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling. Stimulates weakly the intrinsic GTPase activity of the Ras-related proteins RAP1A and RAB5 in vitro. Mutations in TSC2 lead to constitutive activation of RAP1A in tumors.
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Ptm
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Phosphorylation at Ser-1387, Ser-1418 or Ser-1420 does not affect interaction with TSC1.
Phosphorylation at Ser-939 and Thr-1462 by PKB/AKT1 is induced by growth factor stimulation.
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Similarity
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Contains 1 Rap-GAP domain.
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Subcellular location
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Cytoplasm. Membrane; Peripheral membrane protein. Note=At steady state found in association with membranes.
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Subunit
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Interacts with TSC1 and HERC1; the interaction with TSC1 stabilizes TSC2 and prevents the interaction with HERC1. May also interact with the adapter molecule RABEP1. The final complex contains TSC2 and RABEP1 linked to RAB5 (Probable). Interacts with HSPA1 and HSPA8.
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Tissue specificity
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Liver, brain, heart, lymphocytes, fibroblasts, biliary epithelium, pancreas, skeletal muscle, kidney, lung and placenta.
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Biological process
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neural tube closure [GO:0001843]
protein import into nucleus [GO:0006606]
endocytosis [GO:0006897]
heart development [GO:0007507]
negative regulation of phosphoinositide 3-kinase cascade [GO:0014067]
regulation of endocytosis [GO:0030100]
protein kinase B signaling cascade [GO:0043491]
positive regulation of GTPase activity [GO:0043547]
regulation of insulin receptor signaling pathway [GO:0046626]
insulin-like growth factor receptor signaling pathway [GO:0048009]
positive chemotaxis [GO:0050918]
regulation of small GTPase mediated signal transduction [GO:0051056]
negative regulation of protein kinase B signaling cascade [GO:0051898]
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Cellular component
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nucleus [GO:0005634]
Golgi apparatus [GO:0005794]
TSC1-TSC2 complex [GO:0033596]
perinuclear region of cytoplasm [GO:0048471]
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Molecular function
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GTPase activator activity [GO:0005096]
protein homodimerization activity [GO:0042803]
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Alternative product(s)
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top
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Uniprot Identifier
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Difference(s) with the 'canonical' sequence
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Notes
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Sequences
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Isoform 1
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P49815-1
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---
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'Canonical' sequence
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Get Fasta
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Isoform 2
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P49815-2
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946-988 : Missing
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---
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Get Fasta
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Isoform 3
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P49815-3
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946-989 : Missing
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---
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Get Fasta
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Isoform 4
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P49815-4
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1272-1294 : Missing
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---
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Get Fasta
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Isoform 5
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P49815-5
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946-989 : Missing
1272-1294 : Missing
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---
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Get Fasta
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Isoform 6
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P49815-6
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76-112 : Missing
946-988 : Missing
1272-1294 : Missing
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---
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Get Fasta
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Feature key |
Position
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Length
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Description
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Feature identifier
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Region
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Domain
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1531 - 1758
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228
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Rap-GAP
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P49815-DOMAIN-1531
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Region
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1 - 400
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400
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Required for interaction with TSC1
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P49815-REGION-1
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Natural variations
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Natural variant site
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94 - 94
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1
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P -> T (in dbSNP:rs1051616)
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VAR_008019
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Natural variant site
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137 - 137
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1
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H -> R (in TSC; could be a polymorphism; dbSNP:rs45517107)
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VAR_009415
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Natural variant site
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160 - 160
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1
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L -> V (in dbSNP:rs45517109)
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VAR_009416
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Natural variant site
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227 - 227
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1
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C -> Y (in TSC; dbSNP:rs45517122)
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VAR_008020
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Natural variant site
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258 - 258
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1
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K -> N (in TSC)
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VAR_009417
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Natural variant site
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261 - 261
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1
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R -> P (in TSC; dbSNP:rs45502703)
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VAR_009418
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Natural variant site
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261 - 261
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1
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R -> W (in dbSNP:rs45517130)
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VAR_009419
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Natural variant site
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286 - 286
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1
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M -> V (in dbSNP:rs1800748)
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VAR_009421
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Natural variant site
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286 - 286
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1
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M -> T (in dbSNP:rs45517136)
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VAR_009420
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Natural variant site
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292 - 292
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1
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L -> P (in TSC; dbSNP:rs45517138)
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VAR_005646
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Natural variant site
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294 - 294
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1
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G -> E (in TSC; dbSNP:rs45487497)
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VAR_009422
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Natural variant site
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304 - 304
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1
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W -> WGMALW (in TSC)
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VAR_009423
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Natural variant site
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309 - 309
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1
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L -> Q
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VAR_009424
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Natural variant site
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320 - 320
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1
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L -> F (could be associated with TSC; dbSNP:rs1131825)
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VAR_009425
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Natural variant site
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331 - 331
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1
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N -> K (in TSC; dbSNP:rs45517153)
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VAR_008021
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Natural variant site
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361 - 361
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1
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L -> P (in TSC; dbSNP:rs45517147)
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VAR_009426
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Natural variant site
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365 - 365
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1
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Missing (in TSC)
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VAR_009427
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Natural variant site
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367 - 367
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1
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R -> Q (in dbSNP:rs1800725)
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VAR_009428
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Natural variant site
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378 - 378
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1
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P -> L (in dbSNP:rs45517154)
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VAR_009429
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Natural variant site
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407 - 407
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1
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Y -> D (in TSC)
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VAR_005647
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Natural variant site
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440 - 440
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1
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G -> S
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VAR_009430
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Natural variant site
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449 - 449
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1
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M -> I (in TSC)
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VAR_005648
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Natural variant site
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463 - 463
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1
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I -> V
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VAR_009431
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Natural variant site
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486 - 486
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1
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N -> I (in TSC)
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VAR_008022
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Natural variant site
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490 - 490
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1
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I -> V
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VAR_008023
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Natural variant site
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525 - 525
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1
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N -> S (in TSC)
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VAR_009432
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Natural variant site
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536 - 536
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1
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A -> V
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VAR_008024
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Natural variant site
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583 - 583
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1
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A -> T (in dbSNP:rs1800729)
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VAR_009433
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Natural variant site
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593 - 593
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1
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H -> R
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VAR_009434
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Natural variant site
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599 - 599
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1
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K -> M (in TSC; impairs repression of EIF4EBP1 phosphorylation)
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VAR_009435
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Natural variant site
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607 - 607
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1
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A -> T
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VAR_005649
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Natural variant site
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611 - 611
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1
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R -> Q (in TSC and LAM; impairs phosphorylation at S-1387, S-1418 and S- 1420)
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VAR_005650
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Natural variant site
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611 - 611
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1
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R -> W (in TSC; impairs phosphorylation at S-1387, S-1418 and S-1420)
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VAR_005651
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Natural variant site
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614 - 614
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1
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A -> D (in TSC)
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VAR_009436
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Natural variant site
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615 - 615
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1
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F -> S
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VAR_008025
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Natural variant site
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619 - 619
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1
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L -> F (in dbSNP:rs1131826)
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VAR_060584
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Natural variant site
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647 - 647
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1
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D -> N (in TSC; could be a polymorphism)
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VAR_009437
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Natural variant site
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694 - 694
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1
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Missing (in TSC)
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VAR_009438
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Natural variant site
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696 - 696
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1
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C -> Y (in TSC)
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VAR_009439
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Natural variant site
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717 - 717
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1
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L -> R (in TSC)
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VAR_009440
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Natural variant site
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769 - 769
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1
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V -> E (in TSC; could be a polymorphism)
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VAR_009441
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Natural variant site
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802 - 802
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1
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S -> R (in dbSNP:rs1051621)
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VAR_060585
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Natural variant site
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816 - 816
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1
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P -> L (in TSC)
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VAR_008026
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Natural variant site
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826 - 826
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1
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L -> M (in TSC)
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VAR_005652
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Natural variant site
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862 - 862
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1
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A -> V
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VAR_018600
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Natural variant site
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895 - 895
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1
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M -> V (in TSC)
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VAR_009442
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Natural variant site
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905 - 905
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1
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R -> W (in TSC)
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VAR_005654
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Natural variant site
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905 - 905
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1
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R -> Q (in TSC)
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VAR_005653
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Natural variant site
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963 - 963
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1
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V -> M (in TSC; could be a polymorphism)
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VAR_009443
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Natural variant site
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1027 - 1027
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1
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L -> P (in TSC)
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VAR_022919
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Natural variant site
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1084 - 1084
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1
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D -> E (in TSC)
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VAR_005655
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Natural variant site
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1141 - 1141
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1
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A -> V (in dbSNP:rs34870424)
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VAR_057014
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Natural variant site
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1144 - 1144
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1
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V -> M (in TSC)
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VAR_008027
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Natural variant site
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1200 - 1200
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1
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R -> W (in TSC)
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VAR_005656
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Natural variant site
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1227 - 1227
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1
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P -> L (in TSC)
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VAR_005657
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Natural variant site
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1240 - 1240
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1
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R -> W (in TSC)
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VAR_005658
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Natural variant site
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1282 - 1282
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1
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S -> G
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VAR_009444
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Natural variant site
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1295 - 1295
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1
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D -> V (in TSC)
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VAR_005659
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Natural variant site
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1315 - 1315
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1
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P -> S (in TSC)
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VAR_008028
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Natural variant site
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1329 - 1329
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1
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R -> H (in TSC)
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VAR_008029
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Natural variant site
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1341 - 1341
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1
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S -> R
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VAR_022920
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Natural variant site
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1429 - 1429
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1
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A -> S
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VAR_018601
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Natural variant site
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1450 - 1450
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1
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P -> R
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VAR_018602
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Natural variant site
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1497 - 1497
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1
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P -> R (in TSC)
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VAR_009445
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Natural variant site
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1498 - 1498
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1
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S -> N (in TSC)
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VAR_009446
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Natural variant site
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1509 - 1509
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1
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Missing (in TSC; could be a rare polymorphism)
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VAR_005660
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Natural variant site
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1549 - 1549
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1
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Y -> C (in TSC)
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VAR_005661
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Natural variant site
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1594 - 1594
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1
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L -> M (in TSC; could be a polymorphism)
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VAR_009447
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Natural variant site
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1614 - 1614
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1
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Missing (in TSC)
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VAR_005662
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Natural variant site
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1620 - 1620
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1
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H -> Y (in TSC)
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VAR_009448
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Natural variant site
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1636 - 1636
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1
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D -> N
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VAR_022921
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Natural variant site
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1643 - 1643
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1
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N -> K (in TSC; Abolishes GAP activity)
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VAR_009449
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Natural variant site
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1643 - 1643
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1
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N -> I (in TSC)
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VAR_005663
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Natural variant site
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1650 - 1650
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1
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Y -> C (in TSC)
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VAR_005664
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Natural variant site
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1651 - 1651
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1
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N -> S (in TSC; greatly reduces the ability to enhance the RHEB GTPase activity)
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VAR_009450
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Natural variant site
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1653 - 1653
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1
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S -> F (in TSC)
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VAR_018603
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Natural variant site
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1673 - 1673
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1
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V -> L
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VAR_022922
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Natural variant site
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1675 - 1675
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1
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P -> L (in TSC)
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VAR_009451
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Natural variant site
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1681 - 1681
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1
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N -> K (in TSC; Abolishes GAP activity)
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VAR_009452
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Natural variant site
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1690 - 1690
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1
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D -> Y (in TSC)
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VAR_005665
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Natural variant site
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1704 - 1704
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1
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S -> T (in TSC)
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VAR_009453
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Natural variant site
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1709 - 1709
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1
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P -> L (in TSC)
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VAR_008030
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Natural variant site
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1712 - 1712
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1
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A -> E (in TSC)
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VAR_005666
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Natural variant site
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1743 - 1743
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1
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R -> P (in TSC; Abolishes GAP activity)
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VAR_009454
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Natural variant site
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1743 - 1743
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1
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R -> Q (in TSC)
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VAR_008031
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Natural variant site
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1744 - 1744
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1
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L -> P (in TSC)
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VAR_009455
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Natural variant site
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1746 - 1751
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6
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Missing (in TSC)
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VAR_009456
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Natural variant site
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1750 - 1750
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1
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L -> F (in TSC)
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VAR_005667
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Natural variant site
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1773 - 1773
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1
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H -> P (in TSC)
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VAR_008032
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Natural variant site
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1774 - 1774
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1
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S -> T (in dbSNP:rs9209)
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VAR_057015
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Natural variant site
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1783 - 1783
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1
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E -> Q (in TSC)
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VAR_008033
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Natural variant site
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1787 - 1787
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1
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G -> S
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VAR_009457
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Natural variant site
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1791 - 1791
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1
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G -> S
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VAR_009458
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Alternative sequence
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76 - 112
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37
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Missing
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VSP_038355
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Alternative sequence
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946 - 989
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44
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Missing
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VSP_004471
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Alternative sequence
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946 - 988
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43
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Missing
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VSP_004470
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Alternative sequence
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1272 - 1294
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23
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Missing
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VSP_004472
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Amino acid modifications
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Modified residue
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927 - 927
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1
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Phosphothreonine
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P49815-MOD_RES-927
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Modified residue
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939 - 939
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1
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Phosphoserine; by PKB/AKT1
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P49815-MOD_RES-939
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Modified residue
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981 - 981
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1
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Phosphoserine
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P49815-MOD_RES-981
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Modified residue
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1097 - 1097
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1
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Phosphoserine
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P49815-MOD_RES-1097
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Modified residue
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1132 - 1132
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1
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Phosphoserine
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P49815-MOD_RES-1132
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Modified residue
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1155 - 1155
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1
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Phosphoserine
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P49815-MOD_RES-1155
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Modified residue
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1334 - 1334
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1
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Phosphoserine
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P49815-MOD_RES-1334
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Modified residue
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1337 - 1337
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1
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Phosphoserine
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P49815-MOD_RES-1337
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Modified residue
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1338 - 1338
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1
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Phosphoserine
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P49815-MOD_RES-1338
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Modified residue
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1341 - 1341
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1
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Phosphoserine
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P49815-MOD_RES-1341
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Modified residue
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1364 - 1364
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1
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Phosphoserine (By similarity)
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P49815-MOD_RES-1364
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Modified residue
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1387 - 1387
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1
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Phosphoserine
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P49815-MOD_RES-1387
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Modified residue
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1388 - 1388
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1
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Phosphoserine
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P49815-MOD_RES-1388
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Modified residue
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1411 - 1411
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1
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Phosphoserine
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P49815-MOD_RES-1411
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Modified residue
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1418 - 1418
|
1
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Phosphoserine
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P49815-MOD_RES-1418
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Modified residue
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1420 - 1420
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1
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Phosphoserine
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P49815-MOD_RES-1420
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Modified residue
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1449 - 1449
|
1
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Phosphoserine
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P49815-MOD_RES-1449
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Modified residue
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1452 - 1452
|
1
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Phosphoserine
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P49815-MOD_RES-1452
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Modified residue
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1462 - 1462
|
1
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Phosphothreonine; by PKB/AKT1
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P49815-MOD_RES-1462
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Modified residue
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1798 - 1798
|
1
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Phosphoserine
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P49815-MOD_RES-1798
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Experimental info
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Mutagenesis
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939 - 939
|
1
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S->A: Inhibits insulin-stimulated phosphorylation and activation of S6K1; when associated with A-1462
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P49815-MUTAGEN-939
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|
Mutagenesis
|
1462 - 1462
|
1
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T->A: Inhibits insulin-stimulated phosphorylation and activation of S6K1; when associated with A-939
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P49815-MUTAGEN-1462
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Mutagenesis
|
1637 - 1639
|
3
|
KKR->QQQ: Abolishes GAP activity
|
P49815-MUTAGEN-1637
|
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Mutagenesis
|
1745 - 1745
|
1
|
R->Q: Abolishes GAP activity
|
P49815-MUTAGEN-1745
|
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Mutagenesis
|
1749 - 1751
|
3
|
RLR->QLQ: No effect
|
P49815-MUTAGEN-1749
|
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| 1 |
MAKPTSKDSG |
LKEKFKILLG |
LGTPRPNPRS |
AEGKQTEFII |
TAEILRELSM |
ECGLNNRIRM |
IGQICEVAKT |
KKFEEHAVEA |
|
| 81 |
LWKAVADLLQ |
PERPLEARHA |
VLALLKAIVQ |
GQGERLGVLR |
ALFFKVIKDY |
PSNEDLHERL |
EVFKALTDNG |
RHITYLEEEL |
|
| 161 |
ADFVLQWMDV |
GLSSEFLLVL |
VNLVKFNSCY |
LDEYIARMVQ |
MICLLCVRTA |
SSVDIEVSLQ |
VLDAVVCYNC |
LPAESLPLFI |
|
| 241 |
VTLCRTINVK |
ELCEPCWKLM |
RNLLGTHLGH |
SAIYNMCHLM |
EDRAYMEDAP |
LLRGAVFFVG |
MALWGAHRLY |
SLRNSPTSVL |
|
| 321 |
PSFYQAMACP |
NEVVSYEIVL |
SITRLIKKYR |
KELQVVAWDI |
LLNIIERLLQ |
QLQTLDSPEL |
RTIVHDLLTT |
VEELCDQNEF |
|
| 401 |
HGSQERYFEL |
VERCADQRPE |
SSLLNLISYR |
AQSIHPAKDG |
WIQNLQALME |
RFFRSESRGA |
VRIKVLDVLS |
FVLLINRQFY |
|
| 481 |
EEELINSVVI |
SQLSHIPEDK |
DHQVRKLATQ |
LLVDLAEGCH |
THHFNSLLDI |
IEKVMARSLS |
PPPELEERDV |
AAYSASLEDV |
|
| 561 |
KTAVLGLLVI |
LQTKLYTLPA |
SHATRVYEML |
VSHIQLHYKH |
SYTLPIASSI |
RLQAFDFLLL |
LRADSLHRLG |
LPNKDGVVRF |
|
| 641 |
SPYCVCDYME |
PERGSEKKTS |
GPLSPPTGPP |
GPAPAGPAVR |
LGSVPYSLLF |
RVLLQCLKQE |
SDWKVLKLVL |
GRLPESLRYK |
|
| 721 |
VLIFTSPCSV |
DQLCSALCSM |
LSGPKTLERL |
RGAPEGFSRT |
DLHLAVVPVL |
TALISYHNYL |
DKTKQREMVY |
CLEQGLIHRC |
|
| 801 |
ASQCVVALSI |
CSVEMPDIII |
KALPVLVVKL |
THISATASMA |
VPLLEFLSTL |
ARLPHLYRNF |
AAEQYASVFA |
ISLPYTNPSK |
|
| 881 |
FNQYIVCLAH |
HVIAMWFIRC |
RLPFRKDFVP |
FITKGLRSNV |
LLSFDDTPEK |
DSFRARSTSL |
NERPKSLRIA |
RPPKQGLNNS |
|
| 961 |
PPVKEFKESS |
AAEAFRCRSI |
SVSEHVVRSR |
IQTSLTSASL |
GSADENSVAQ |
ADDSLKNLHL |
ELTETCLDMM |
ARYVFSNFTA |
|
| 1041 |
VPKRSPVGEF |
LLAGGRTKTW |
LVGNKLVTVT |
TSVGTGTRSL |
LGLDSGELQS |
GPESSSSPGV |
HVRQTKEAPA |
KLESQAGQQV |
|
| 1121 |
SRGARDRVRS |
MSGGHGLRVG |
ALDVPASQFL |
GSATSPGPRT |
APAAKPEKAS |
AGTRVPVQEK |
TNLAAYVPLL |
TQGWAEILVR |
|
| 1201 |
RPTGNTSWLM |
SLENPLSPFS |
SDINNMPLQE |
LSNALMAAER |
FKEHRDTALY |
KSLSVPAAST |
AKPPPLPRSN |
TVASFSSLYQ |
|
| 1281 |
SSCQGQLHRS |
VSWADSAVVM |
EEGSPGEVPV |
LVEPPGLEDV |
EAALGMDRRT |
DAYSRSSSVS |
SQEEKSLHAE |
ELVGRGIPIE |
|
| 1361 |
RVVSSEGGRP |
SVDLSFQPSQ |
PLSKSSSSPE |
LQTLQDILGD |
PGDKADVGRL |
SPEVKARSQS |
GTLDGESAAW |
SASGEDSRGQ |
|
| 1441 |
PEGPLPSSSP |
RSPSGLRPRG |
YTISDSAPSR |
RGKRVERDAL |
KSRATASNAE |
KVPGINPSFV |
FLQLYHSPFF |
GDESNKPILL |
|
| 1521 |
PNESQSFERS |
VQLLDQIPSY |
DTHKIAVLYV |
GEGQSNSELA |
ILSNEHGSYR |
YTEFLTGLGR |
LIELKDCQPD |
KVYLGGLDVC |
|
| 1601 |
GEDGQFTYCW |
HDDIMQAVFH |
IATLMPTKDV |
DKHRCDKKRH |
LGNDFVSIVY |
NDSGEDFKLG |
TIKGQFNFVH |
VIVTPLDYEC |
|
| 1681 |
NLVSLQCRKD |
MEGLVDTSVA |
KIVSDRNLPF |
VARQMALHAN |
MASQVHHSRS |
NPTDIYPSKW |
IARLRHIKRL |
RQRICEEAAY |
|
| 1761 |
SNPSLPLVHP |
PSHSKAPAQT |
PAEPTPGYEV |
GQRKRLISSV |
EDFTEFV |
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>sp|P49815|TSC2_human Tuberin
MAKPTSKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELSMECGLNNRIRMIGQICEVAKTKKFEEHAVEA
LWKAVADLLQPERPLEARHAVLALLKAIVQGQGERLGVLRALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEEL
ADFVLQWMDVGLSSEFLLVLVNLVKFNSCYLDEYIARMVQMICLLCVRTASSVDIEVSLQVLDAVVCYNCLPAESLPLFI
VTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCHLMEDRAYMEDAPLLRGAVFFVGMALWGAHRLYSLRNSPTSVL
PSFYQAMACPNEVVSYEIVLSITRLIKKYRKELQVVAWDILLNIIERLLQQLQTLDSPELRTIVHDLLTTVEELCDQNEF
HGSQERYFELVERCADQRPESSLLNLISYRAQSIHPAKDGWIQNLQALMERFFRSESRGAVRIKVLDVLSFVLLINRQFY
EEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLSPPPELEERDVAAYSASLEDV
KTAVLGLLVILQTKLYTLPASHATRVYEMLVSHIQLHYKHSYTLPIASSIRLQAFDFLLLLRADSLHRLGLPNKDGVVRF
SPYCVCDYMEPERGSEKKTSGPLSPPTGPPGPAPAGPAVRLGSVPYSLLFRVLLQCLKQESDWKVLKLVLGRLPESLRYK
VLIFTSPCSVDQLCSALCSMLSGPKTLERLRGAPEGFSRTDLHLAVVPVLTALISYHNYLDKTKQREMVYCLEQGLIHRC
ASQCVVALSICSVEMPDIIIKALPVLVVKLTHISATASMAVPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSK
FNQYIVCLAHHVIAMWFIRCRLPFRKDFVPFITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRIARPPKQGLNNS
PPVKEFKESSAAEAFRCRSISVSEHVVRSRIQTSLTSASLGSADENSVAQADDSLKNLHLELTETCLDMMARYVFSNFTA
VPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSLLGLDSGELQSGPESSSSPGVHVRQTKEAPAKLESQAGQQV
SRGARDRVRSMSGGHGLRVGALDVPASQFLGSATSPGPRTAPAAKPEKASAGTRVPVQEKTNLAAYVPLLTQGWAEILVR
RPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRDTALYKSLSVPAASTAKPPPLPRSNTVASFSSLYQ
SSCQGQLHRSVSWADSAVVMEEGSPGEVPVLVEPPGLEDVEAALGMDRRTDAYSRSSSVSSQEEKSLHAEELVGRGIPIE
RVVSSEGGRPSVDLSFQPSQPLSKSSSSPELQTLQDILGDPGDKADVGRLSPEVKARSQSGTLDGESAAWSASGEDSRGQ
PEGPLPSSSPRSPSGLRPRGYTISDSAPSRRGKRVERDALKSRATASNAEKVPGINPSFVFLQLYHSPFFGDESNKPILL
PNESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVC
GEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIVTPLDYEC
NLVSLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRICEEAAY
SNPSLPLVHPPSHSKAPAQTPAEPTPGYEVGQRKRLISSVEDFTEFV
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