(CASP4) caspase 4, apoptosis-related cysteine peptidase [Homo sapiens] |
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Gene
Transcript(s)
Exon(s)
Protein(s)
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Accession
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6327
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Official symbol
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CASP4
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Official name
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caspase 4, apoptosis-related cysteine peptidase
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Gene type
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gene with protein product
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Organism
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Homo sapiens
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Location
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Chromosome 11 (NC_000011.9) : 104813593...104839324 (-)
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Map
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11q22.2-q22.3
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Length
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25732 nt
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NM_001225.3
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CASP4, mRNA isoform alpha
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NM_033306.2
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CASP4, mRNA isoform gamma
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Accession
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Name
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Organism
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Length
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P49662
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Caspase-4
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Homo sapiens
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377 aa
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A2NHL8
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Caspase 4, apoptosis-related cysteine peptidase [submitted name]
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Homo sapiens
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377 aa
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A2NHM0
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Caspase 4, apoptosis-related cysteine peptidase, isoform CRA_c [submitted name]
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Homo sapiens
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321 aa
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Synonyms |
Mih1/TX; ICEREL-II; TX; ICH-2; ICE(rel)II
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Alternative name(s) |
apoptotic cysteine protease Mih1/TX; caspase 4, apoptosis-related cysteine protease
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Summary |
This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq].
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Related Articles in PubMed
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Go to ensembl
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1 |
TACATAGTTT |
ACTTTCATTT |
TTGACTCTGA |
GGCTCTTTCC |
AACGCTGTAA |
AAAAGGACAG |
AGGCTGTTCC |
CTATGGCAGG |
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81 |
TGAGTCCTTT |
TCTGACTAGG |
AGTTTGGGAG |
TAGGAACTTA |
GAAAACACTT |
GATTTATTGC |
TCTGAAATAA |
ACACAAGAAA |
|
161 |
GGAAGTGAGC |
CGATAGCACA |
CATGTTGAAT |
TCCTTTTCTT |
ACTGATTGTG |
TGTAGTTTGA |
ATCATGGGAC |
CTGGTGTTAG |
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241 |
AGATATTGAC |
GGAGGTCATA |
TGTTTTCCAG |
ATGTCTTTGA |
GCCAGAAAGA |
AGTTAATTCC |
TTTCTTTCAG |
CTTCTGGTAA |
|
321 |
TCAAAGGGAG |
GGTAAAGAAA |
GCCAGAGGAA |
GTTATTTGTG |
TGAGACAATT |
CTAGAAGTTT |
CGAAATGCAC |
TCTGAAATCT |
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401 |
TTCTTTTGAT |
TCCAAATTAA |
TTGCCCAGAT |
CACAAACCTT |
TTTCGCAGAA |
TCAGATCTGA |
GAGCCTCTGA |
ATTGTTATCT |
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481 |
TCTTCGACAT |
CTCTTATTGT |
GAATTACATT |
CTTGGTCTGT |
TTAAAGTGAT |
TCAATTTTTT |
CCTCTTTCTC |
GTTGGTCCTG |
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561 |
ATACTGACTA |
CTTTAATATA |
ATATTTCATG |
GGTTAATATC |
ACAGTTGTTT |
TGTTTTGCCG |
TTGTTATTGT |
TTTTAACTGG |
|
641 |
TATCCTTCCC |
TCCAGGACTT |
AACTCTCCAA |
TCCATTCTGC |
ACACAACTTT |
TAGGTCACCT |
GTCTTATACA |
CAGAAGCTGA |
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721 |
AAAAGCCTAA |
GGGATAGAGT |
TACTTAGGCA |
GCTAGTATTC |
CAGCAGGTCA |
TAACGCTTCT |
TTGGCTTCAT |
TCTCCTCACA |
|
801 |
GGAAAAGGAA |
GAAATTGGAC |
TAGATCAGTG |
AATTCTAAAC |
CTTATAACAT |
ATCGCAGCAA |
TCTGTAGTCA |
TATAAAAAAA |
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881 |
GTCAGATGAC |
TACCCCCTTC |
CTCACCGCGA |
ATAGCTCAAT |
CTTAAATACC |
CTGCAGGCAT |
TTATTACCTT |
TGAAGATCGT |
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961 |
CACATAATTC |
TTATGAAACT |
GACTTGACAT |
AGGTTTGTTC |
TATTAGGAAA |
GTTGACCAGT |
TAGTTAACAC |
TCTCTGCTTA |
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1041 |
TCTGCTAGTG |
ATCTATTAAT |
GTAATTAACT |
TTGCTCAGGG |
ACATACAGTG |
GCTCCCTATT |
GCCTTTTCTC |
TTTTTTACTA |
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1121 |
TCTGAACTTT |
CAGACAATTT |
TTTCTACCTT |
TTGAAACATG |
TGTATCCAGT |
TTTTCCATTA |
ATCTTTGTAA |
AGCATGATTT |
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1201 |
CAACTTCATA |
AAAAAATACT |
GTATTTACTT |
CACTCATATT |
ACCTTGTTGT |
TGTTTCTTTA |
CTCCTTTGAT |
TCTCCCTATA |
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1281 |
GAACAATTCT |
CTCCGGGGTT |
TATGTCTAAC |
TTCACAACAT |
TTAACTTAAG |
CTCTGGAATC |
AAGGGATCAT |
TAGATAAAGA |
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1361 |
TAGGGTAAAT |
TGAAAGCCAC |
TAGTCAAAAA |
CAAGTCGTGG |
TTTGATAATT |
ATAAACAACC |
AAATGTAGAC |
AGCTATTATT |
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1441 |
ACCTTAAACT |
CTTGAGGAAT |
TGTATCCTGT |
AATGTGTTTA |
AGCATTACAT |
CACTTTGCCT |
GGAACCAAAA |
CTGTGGTCCT |
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1521 |
GATAAGTTTT |
TTCCTCTAAT |
TGATTCCTGC |
CATTTTTATT |
ATCACTGCAG |
CTTTCATTCA |
GTGATTATTA |
TAATAACAAA |
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1601 |
AAATAATCTA |
TAGTAACCAT |
TTCTTTAAAA |
AATACTTACC |
ATATGATAGC |
TAATTCATGC |
ACTCTCTCTG |
ATTTAATATT |
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1681 |
TAACATCAAT |
CAATACAGTT |
GTGCTATTAT |
TTCCATATTG |
TAGTTGAAGG |
GGATACTTAG |
AGAATGCCTC |
CAAAATATGC |
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1761 |
TTTAGGTCAA |
AAGTCTGTTG |
AGAGGAGTGG |
TCTCAGGTTG |
GCATGACTCT |
CAAACTCTGC |
CATTAATCTA |
ACTTTCTGCA |
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1841 |
AACATCTTCA |
AATACTTGCC |
CTGTCTCTGA |
TCACTGCCAC |
TTCAGTCCTG |
GCCTCACATT |
TCTATTCCTT |
CTAAAGCCCA |
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1921 |
GCTCTCCCAG |
TTTTCTGGTT |
ACACGAGACA |
CCCTCAAGCC |
TTTGTGCTTT |
TTTCCTTACT |
GCTCTCTGCC |
AAAAGACCAG |
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2001 |
CTCCTAGTTT |
TCCAGGGGAC |
AAATTCCTAC |
CAGTCCTTCA |
GGTCTCAGTG |
CCAAGCCCTC |
CCTTCTCTGG |
ACAGCTGTAC |
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2081 |
CTGAGACACA |
CTTTGCTTAT |
GCTTTTCTTG |
AGCTTCTGCT |
AATTATTTAC |
ATTCTTATAA |
TATTTTTCAT |
TTTACTTATT |
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2161 |
TGCATATGTA |
TTTTTCCACT |
TGACTGCAAA |
CTTCAAAGTG |
TACAGACATG |
CTGCCAAAGT |
GGTACCCCCA |
ATAACAGCAG |
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2241 |
AGTAAGTTTC |
AAGAATTTAT |
GCTCATTAAA |
TATACCTGAA |
TGGATAGGGG |
AATGAACATG |
CCTTCCTTCT |
GTTGAAATAT |
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2321 |
CCAACATGCA |
ACTATCATCT |
ATTAAATGAA |
ATCAAACTTA |
CCTGGTTTGC |
TATTAAGAAT |
TTGTAATCAC |
CAGGTGGGTT |
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2401 |
CACCTTGCCC |
ACTGCTTAGA |
CAGAGCCAAT |
TTATCAAGAC |
AGGGGAATTG |
CAATGGCGTA |
AGAGTAATTC |
ACGCAGATCC |
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2481 |
GGCTGTTCTG |
GAGAGGGTAG |
TGTTATTATT |
ACTTAAATCA |
GTCTCCCCGA |
GCATTCAGAA |
ATAAGAACGT |
TTAAAGATAA |
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2561 |
TTTGGCAGCT |
AGGGGCTTGG |
GAAGTAGGAA |
GTGCTGATTA |
CTCAGGTGGG |
AGATGGAATC |
ATAGGGTGTC |
AAAGTGAGGT |
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2641 |
TTTCTTGCTG |
TGTTCTCTTC |
CTGGGTGTGA |
TGGCAGAACT |
GGTTGGGTTA |
GATTACTGGT |
TTGGGTGGTG |
TCAGCTGATC |
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2721 |
CATTGAGTGC |
AGCGTCTGAA |
AAATATCTTA |
AGTGCTGATA |
TTAGATTTTA |
TAAAGTGATA |
TTATCCCTGG |
GAGCACAATG |
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2801 |
GGGACATTCC |
AATTCTAGGA |
GCCAGAGGCT |
GCATGTCCCT |
TACATTGTAA |
TTTTTAGTCT |
TGTAGCTAAT |
TTGTTAGTCC |
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2881 |
TGCAAAGGGA |
GACTGGACCC |
CAGGCAAGAA |
GAGGGTCTTT |
TCGAGAAAAG |
GCTGTTACCG |
GTTTTGTTTC |
AGTCAAACCA |
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2961 |
TGAACTGAAT |
TCCTTCCCAA |
AGTCAGTTCG |
GCCTATGCCC |
AGGAATGAAT |
AAGAACAGCT |
TAAGGGATAG |
AAGCAAGATA |
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3041 |
GAGTTGGTTA |
GGTCTTATTT |
CTTTCACTGT |
CGTAATTACC |
TCAGTTATAA |
TATTGCAAAG |
GCAGTTTCAA |
TCCCTCTGTT |
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3121 |
TGGGTTTTCT |
AATAGCTTAA |
TCTTAAGGTG |
TAGGCTATGA |
AGATGGGAAA |
AGGCTGTCGA |
TCACTCTGGC |
TTCTTCCTGC |
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3201 |
TGACAGGAGA |
CATAGTGGAA |
ATTAGAGTGA |
ACCCCAAGGT |
GAGAAGAATG |
TAACCACTTT |
GCAACTGTCT |
GAGCATACTC |
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3281 |
ATGCAGGACT |
GGCTGGGCTT |
CCAATGCTTG |
CAATGCAAAA |
ACATTAGTAC |
TCTCCTCTGT |
AGTTTTGCTA |
TAATATTTAA |
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3361 |
GCCAACAGCC |
TCCTGTAAGG |
TAAATAACAA |
ATCCTAGGAT |
GAGGAGTACA |
ATTCTCAATT |
TTAAAAGCAA |
AGATTGGAAA |
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3441 |
GCATTAATTT |
GGGGACTTCT |
AATCCACAAA |
GAATTTAGGA |
TTTAGTCCAA |
ACTGTAGGAA |
AAAACTCAAA |
CAAAACTAAC |
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3521 |
AATGGGTATA |
TTATATGTTT |
TCTTTTGAAG |
CATAATTTTT |
CTCTCCAGAC |
CCTATTTTTA |
TTAAAAGTAA |
ATTATAATAG |
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3601 |
AACTAATCTG |
TTTACCAAAA |
TAAGCTTTAG |
TCTTACTGTA |
CTTGGCCTGA |
TTATTTGCAT |
GAAGTGCAAC |
AAGAATAATT |
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3681 |
ATTTTTTATT |
TAGGCTGTTT |
TTTGTTTAAA |
TTGGCTTTGA |
TGGAACTCTG |
TTCCATGAGG |
AATCTCAGAT |
AAGACTTTTT |
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3761 |
AAGAGCCAAT |
CCCAGCCATG |
CATTTGTACC |
CTTAAATACC |
TATGAGTTGG |
GTAAATTCCT |
CTCCTCTCAA |
GGTCCCAAGA |
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3841 |
TAACTTGGAG |
CTCATGAACC |
TGTTAGAAAG |
TGATATTCTT |
TACTTACTAC |
AGATCAAGAA |
CCTTGTACAA |
GGACTCTGTG |
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3921 |
TAGACAAGGT |
ATGAAGCCAG |
ATTCCCCAAG |
GGGCTTTTAT |
TGGCTCTGTA |
AGTCAACTTC |
GATTCTTTAA |
GGGAAGAGTG |
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4001 |
CCATTCCAGT |
CAAAGCCTTG |
GTAAAATAAC |
CAATTTCTCC |
AATTGTGTCA |
TGTTACAAAA |
GAAAACAGAT |
TTTTATTGTG |
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4081 |
CTTATGGAAT |
TAACCATGCT |
GCCATAAATT |
GAGAATACTT |
ACAAAGAGTT |
TCCAAATTCT |
GGAGAAATCA |
GGTAGAGAGA |
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4161 |
AACAAATATG |
CTTCAAAATT |
TTTTCACAGG |
AGTGTATTTT |
ACCTACTTGT |
TAAAAGTTGC |
AAATATCTCT |
AAAGAAATAA |
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4241 |
GTTATCTTGA |
CTGTGAAAAC |
TGAAGGATTG |
GTGACATTTA |
AGACATCAGC |
TCTTCATGAG |
AGTCCTGGAA |
GTTTTGTTTT |
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4321 |
TTTCCTCTAT |
TCCAATAGCA |
CAATTTTTAA |
AGTTATCTGA |
GACCTGCACT |
CAGAGTCCTA |
TACCTGATTA |
TAAACTGCCT |
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4401 |
TTTGAAAACG |
ACCAAAGCAA |
GACAAAATGT |
CTGTGGATGA |
CAAAAGTCTA |
TAGACACTAT |
TAAAGCTATA |
ATTGACTAGG |
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4481 |
AATTTTGCTT |
ACTTCTGTGG |
CATCCAACAA |
TTTTGTATAA |
CAATTATAAT |
TACTAATAAT |
GTACAGTAAA |
TTTTATCAGA |
|
4561 |
ATTATAGAAG |
TTTATATAAA |
TACACAGACA |
GACAGAAAAT |
TCAGCACTTG |
TAAGATTTTT |
TATTTGCCAG |
TTGTTAACTG |
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4641 |
GACTACTGGC |
TTCAGAGTGG |
AGCCCTTGGA |
GGAACAGGGC |
CAGGAAAGCA |
TGCATTTTTT |
TTCCAAGCTA |
AATAAGCAGG |
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4721 |
CACAGCTGAA |
GGCAAAGACA |
GATCTCCAAA |
ATGAAGGATG |
CCATTTTATA |
CTGGATCCCA |
GATCCCCAAA |
AGGAAGGAAA |
|
4801 |
TACTACTGGA |
GAAGAGAGTG |
CAGTGCTTCT |
AACCTGCATT |
TTATTGCAAG |
GCAACCTAAA |
GCCAATCAAC |
CCATTTTGAA |
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4881 |
ATCAGCCCAT |
CCCCCATGGA |
AGTCTCATCT |
CTCAGTCAGG |
CATGGGGATG |
TTTCCGTATC |
TTCCAGGTGG |
CCCAGAGCAT |
|
4961 |
GCTTCTCTGA |
CCCAAGTGTG |
CGAAGAGCCA |
AGTTTCCCTC |
TGAAAATACT |
ATTAGCCATC |
CCTTAAAGTA |
TATTTCCTAC |
|
5041 |
CTAGTTATTA |
CATACCAAAG |
CTATCTCATA |
ATGCAAAGTA |
ATTTCTGATA |
TCCCCAAAAT |
TCAAACTGTC |
AGATAACACA |
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5121 |
ATGCAAAACA |
GAACAGAGCC |
TTTGATTTTG |
AGAGTGATCC |
ATCTACTTTT |
AATTCCTTGG |
TTGTCATGAA |
GAAAACAGAG |
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5201 |
GGTTTTTTGT |
TTGTTTCTTG |
TTGTTTGTTT |
TTCCCAAAAT |
GGGGTCTGTG |
GTGCTTCCTC |
TGTTTTTCTC |
AAGGAGTCTC |
|
5281 |
AGGCTACCAA |
AAGTTATCTT |
AGTGCCTCTT |
ATGTGTGCAT |
TAAGAGTGGC |
AAGACAAAAA |
ATGGAGAAAA |
ATAATTCAGT |
|
5361 |
TTACTAAGAA |
GAAAAAACCC |
TCTTTTACAG |
AAAAACGAGA |
TCCAAGAAGA |
GAAAAACATA |
AAGGTCTTTT |
AAATGTATCC |
|
5441 |
ATAACTTGTT |
TATTCACTTT |
TAATTAAGCT |
GACTTTTAAC |
CTTAGTGCTC |
TTAACAAAAT |
CCTTTTAAAT |
TTCGTATTAC |
|
5521 |
CCAACTTTAG |
CCATGCGGCC |
AACATTTCTG |
GCTTTTGAAC |
TTTATCAAAA |
GTAACTTCCC |
AGGTGCTTCA |
AAGGTGTGGT |
|
5601 |
AAGCAGTTTC |
TTTTTACAAG |
ATTTAGAATT |
TCCCCAAGGT |
AGTCCAGAGA |
AAGGAAAATT |
CAAGAGAGGA |
AATCAGAAGC |
|
5681 |
TATCCATGGG |
GTTGTGGGGG |
AACCTCATTA |
AATGGCAAAG |
TTATGCAAAT |
AGCAAACCAG |
AAGGAAATTG |
TTCCAGAAGC |
|
5761 |
CAAGAATAGA |
GCCTGAGCCT |
CTATGTCAAA |
AGGCAAAGTC |
TTAGCTACTG |
AATTACAGCA |
TTGAGCAGTT |
TCTATTGCTA |
|
5841 |
TTCCAAGAAG |
GAGACTAGAG |
AAGCCACTTT |
TAACCTTGCC |
AAGGCTTTTA |
ACTGCTCAAG |
AAAAATTTTT |
AGGGCTGGAT |
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5921 |
GGTATAAACC |
AAAAGGAAGT |
ATCCACATAT |
GGTCACAAGA |
TTAAGCTCTT |
AAGGAGGCCA |
AACAAGACAG |
AGAAATTTCA |
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6001 |
TACAGTATTG |
GTTTCAGGGA |
CCCATTATAA |
TTGGCCAGCC |
TGCTGAGCTG |
GCTTGAAAAG |
CAGGCTTATA |
GGGGTCCTAA |
|
6081 |
ACCCATGTTC |
TATCTTGTGA |
TACCCCTCTT |
TCCATTACAG |
AACACTGAAA |
GACAAATTCT |
TAGCAAAAAT |
ACACCAGATT |
|
6161 |
TGCTATAGGC |
TAAGACTAGT |
CTTGTAAATT |
CTTTTTTCTA |
TTAATCAAAA |
CTTTACAGAG |
AAACATATAG |
TGATGTTTAC |
|
6241 |
TGTTTACACA |
GATGGAGAAA |
GAGAGAGAGA |
CCAGAAACCT |
AGCTGGTAAG |
AATTTCTTAC |
ACTTTTTGCT |
GGCATACCAG |
|
6321 |
ATTTCTGGGT |
GCCTTTTCTC |
TGTAACTTCC |
AGAAGAACGG |
AACGGCTTCT |
GATCAGCCTG |
CTCACCTCAC |
CATAGTTGTG |
|
6401 |
GGGTTCAAGC |
CACTTTACAA |
GAAAAAAGTC |
ACCATTTTCT |
GTTTTATGGA |
AACATAGGCA |
AGATTCTTAA |
AATGCAAGAT |
|
6481 |
GCTGCCCAAC |
CAGCTGCATG |
GGGAACCATT |
TAACATTTTC |
TATCCCAGCA |
GAATTCACAT |
AACAAAACAG |
ACACTAGTCA |
|
6561 |
CCTCGTTCAG |
CACCCAATAT |
CAACCTGGCA |
AAGCTCAGAC |
TTTTTTCTGT |
TCGTCCCTGT |
TGTCTTTGAT |
CCACTCCAGG |
|
6641 |
TGGGGAGGGA |
CGACCTCAGA |
ACAGTAATTC |
ACAATGGGGT |
CTCTGGGTAA |
GGCAAAGAGC |
AGATAGTCAC |
CATGAGACAG |
|
6721 |
GCCTATTGAA |
CTTTCTCCAG |
GGCTCATCGA |
ATGTAACCAA |
ATAAGAAGAG |
TCCTCTGAGT |
TAGGCCTGCT |
GGACTTCCTT |
|
6801 |
CAGCAATTCC |
TTCTGAGATT |
CCCTCCACAT |
ATACAAACAC |
ACACGAAGAT |
GAGACAGACA |
GAAGGCCTTC |
CAAATCAGAT |
|
6881 |
GATCCCTAAA |
CAGGAACTCC |
AAGAGTATCC |
CTTCCAAACT |
ATCCTCCTAT |
TCTCTGTCTG |
AGAAATCTCA |
AAATTGTCCT |
|
6961 |
GATTGAGGAC |
AAGTCTCGTG |
AACCAAGACT |
CTTCCTACTA |
GTTAGAGCCA |
ACCAAGACCC |
CAGTGGAGCC |
GAACAGATAC |
|
7041 |
CCCGTGGTGG |
AGCTACAAAC |
AGACACCCTG |
CAATGGGGCT |
ACAGACACCC |
TGCAATGGGG |
CTACAGACAC |
CCCATCATAG |
|
7121 |
AGCTACAGAC |
AAGTCGAGAG |
AAGGAAGGAG |
GCATTAGCAG |
TGCCTAGTAG |
ATTCACCAAT |
CCTAACACCC |
TGCAATGGGG |
|
7201 |
CTACAGACAG |
ACACCCCACT |
ATGGGGCCAC |
AGAACCAGTC |
AGGAGAAGGA |
AGGAGGCATT |
GGCAGCACCT |
AGGATACTCA |
|
7281 |
CCAATCCAGA |
CACCCTTCAA |
TGCAGCTACA |
GACGGAAACC |
CTGTGATAGG |
GCCACAGTTA |
GAGGACATCT |
CTCCAGGATT |
|
7361 |
ATTTCTCCGT |
TGCAATTAAA |
TGCATGCACA |
TTGGGTTGGC |
AGTGCCTGCC |
AGTGGAGAGA |
GTACCAGAGC |
CAGCCCCCAG |
|
7441 |
TCCAAGAGAA |
CTAGGCGGCT |
ACTTGGGCTA |
CCTTCTGGAT |
CCATCGCTGG |
AGCGGGGGCA |
CCAAACCACA |
AGCAGGTAGC |
|
7521 |
CACAAAGGCT |
TTCCCAGTCT |
GATTTCGTTC |
ATTGTTGTAA |
TTTCCTCAGT |
TATAATTTTG |
CAAAGGTGGT |
TTCATATTCC |
|
7601 |
TTAAGAGTTG |
AGCCACACAT |
AAGTTTTATT |
CATTTGTTCC |
TACATGGACT |
TGACTACTGA |
TTCAGTAAAT |
AATTAGTAAA |
|
7681 |
TATTCAGTAA |
ATAACTAGTA |
AAAAGAATGC |
CAAAAATAGT |
GCAGATGTAG |
TTCATGGCCC |
CTGTCCTCAC |
AGAGCATAAA |
|
7761 |
TTCTAACAGT |
GGATAGAGAT |
AAGTAGGCTG |
GGAATCACAA |
TTAAATGGAA |
AAATAAAAAA |
AAAGGCTGGA |
TGTGGTGGCT |
|
7841 |
CAGGCCTGTA |
ATCCAATAGC |
AGCAATTTGG |
GAGACCAAGA |
TGGGTGGATC |
ACCTGAGGTC |
AGGAGTTCGA |
GATCAGCCTG |
|
7921 |
GCCAACATGG |
TGAATCCCCA |
TCTCTACTAA |
AAATACAAAA |
ATTAGCCAGG |
CGTGGTTGTG |
TGCACCTGTA |
GTCCTAGCTA |
|
8001 |
CTCAGAAGGC |
TGAGGCAGGA |
GAATCGCTTG |
AATCCGGGAG |
GCAGAGATTG |
CAGTGAGCCA |
AGATAGCACC |
ACTGCACTTC |
|
8081 |
AGCCTGGGTG |
ACAGAGTGAG |
ACTCTGTCTC |
ACAAAAATAT |
ATAAATACAT |
AAATAAATAA |
ATGGAAAAAA |
AATGCTACTC |
|
8161 |
TAAGGAGATA |
CAAGGTGCCC |
TAGGAGCATA |
TATCTCTGAT |
GCTGTCTCCT |
CTGGAAGAAT |
CAGAGAGGAT |
TCCCTTAAGA |
|
8241 |
AAATACCATC |
TAATCTGATA |
CTTGAAGGAT |
AGACAGATAG |
ACAGATAGAC |
AGAGAACAGT |
TCAAAAACCA |
GAAGAAATTA |
|
8321 |
GAAGCGGGGG |
TGCTGAAACT |
ATACAGATCC |
CTAAGTAGAG |
ACTTGATTCC |
CTGAGAAAGG |
TGCCATCTAA |
TCTGAGACTT |
|
8401 |
GAAGGTTAGA |
CAGACAGCAG |
TAGGAAAACA |
AGAATGAATG |
AGAAGGTAGG |
GGCTGGAAAT |
ACAGAGACCC |
CTAAATAGAA |
|
8481 |
TCTTTCCAGA |
AATTAAATGA |
AGGCAGAACG |
TTTTGAATGT |
AATGAGCAAG |
GTGGGAACAG |
TATCAGAAAA |
TGAGTGAATG |
|
8561 |
AGAAGGCCTA |
GATTAGAATA |
GGCTGAAAGT |
TTTCATGGTC |
AAATCTAGAT |
ATTGGAACAC |
TCTTCGTTGC |
AAAGAGTAGA |
|
8641 |
ATAGAGGGAC |
GGAGAGTAGA |
TTGATAAAGT |
TCTTATGAAT |
TTATTTCTTA |
AGAAAGAAAG |
GATGTTGGCC |
CGAATAGAAG |
|
8721 |
TAATGAACAA |
TTAGAATTGA |
GAGAAGTGGT |
CAGATTCTGA |
AAATGTTTAG |
CAAATAAAAT |
CGATGCAATG |
TGAATTAAGA |
|
8801 |
AGGGAAATAA |
GACATAGAGA |
AGGCCAAAGA |
GGTTGAATAT |
CACCAGGTAT |
TGCTGCTCTT |
TTGTACTTGG |
AGTATAGGTA |
|
8881 |
TTATTTACTA |
GTATATGGAA |
AAGAGAATGA |
AGGATGGAAA |
TGAAAAAATG |
AACAGTTCAT |
CTTTGTAAGT |
TGAGTTAAAT |
|
8961 |
GAGGTTGTGA |
GATGTAGTTG |
AGATATCTCA |
TTGTCTATTG |
AATGTATAGG |
TTTCAATACC |
GACATCCACA |
TCTGGGCTGA |
|
9041 |
ATCCATAAAT |
TTGAGAATGA |
TTTATTTATT |
CTTTTAAGCA |
TATAATGGAT |
GCCATCAGAA |
TGTGTAGATT |
ATACCTCAGG |
|
9121 |
CCATACTTTT |
AATTTACTTA |
TTTATTTATT |
TGACAAATAA |
ACATTGTACA |
TATTTTCTAT |
GTACAACCTT |
CTGCTTTTAT |
|
9201 |
GAGTTTAACC |
TGTTTAGAGT |
CTATGTATAA |
GTGAGATAAT |
GTGATATTTT |
GTGTTTTGGT |
GCCTGGCCTG |
GCTTATTTTA |
|
9281 |
CTTAATATAA |
TGTTCTTCAT |
GTTCATCAAT |
ATTGTCAGAA |
ACGATAGGAT |
TTACTTCCAT |
TTAAAAGCTG |
AATAGTGTTG |
|
9361 |
CATTTTGTAT |
ATAATCCACA |
TTTTCTTCAT |
CTATTAATCT |
GTCCACAGAC |
ATTTAGGTTG |
ATTTTATATC |
TTGGCTATTG |
|
9441 |
TGAATAATGC |
TGCAATGGAA |
ATAGAAGTTC |
AGATATCTCC |
TCGAGACACT |
GATTTTCCAA |
TTTTTGATAT |
ATACTTAATA |
|
9521 |
GTGGGATTGC |
TTGATCATAT |
CTTTAGCTCT |
ATTTTTAACT |
TTCAGAGGTG |
TCTCCATATA |
GGTTTCCATA |
AAGACCATGC |
|
9601 |
TAATTTACTC |
TTTTTTTTTT |
TTTTTTTTTT |
TTTTTTTGAG |
ACAGAGTCTC |
ACTCTGTTGC |
CTAGGCTGGA |
GGGCAGTCAT |
|
9681 |
GGAATCTAGG |
CTCACTGCAA |
CCTCCGCCTC |
TAGGGTTCCA |
GCAATTCTAC |
TGCCTCTGCC |
TCATGAGTAG |
CTAAGATTAC |
|
9761 |
AGGCGCCCAC |
CACCACGCTC |
GGCTAATTTT |
TGTATTTTTA |
CTAGAAGCAG |
GGTTTTACCA |
TGTTGTCCAG |
CCTGGTCTAG |
|
9841 |
AACTACTGAC |
CTCAGGTGAT |
CTGCCCGCCT |
TAACCTCACA |
AAGTGCTGGG |
ATTACAGTCG |
TGAGCCACTG |
CGCAGGGCCT |
|
9921 |
AATTTACGTT |
TTACCAACAG |
TGTACAAGAG |
TTTCTTTTTT |
TCTACATCCT |
CTCCACCATT |
TGTTATCTTT |
TGTCTTTTTG |
|
10001 |
GTAATAGCCA |
TTCCAACAGG |
TGCAAAGTGA |
TATTTCATTG |
TGACTTCAAT |
TTCCCTGGTG |
GCTAGAGAGG |
TTGATCATTT |
|
10081 |
TTCATATACA |
TATTCTCTGT |
ATGTCTTCTT |
TTGAAAAGTG |
TTTATTCTGG |
TCCTTTGCTT |
ATTTCTAAAT |
CAGTTTATTT |
|
10161 |
TCTTTCTATT |
GAATTGTTTG |
TGTTCTTTGT |
ATTTTGCATA |
TTAATTCTTT |
ATCAGATGTA |
TGGTTTGCAA |
ATCTTCTCTA |
|
10241 |
CCATACTGTT |
GATTATCTCT |
TTAATCTTTT |
GATTGTTTCT |
TTGACTGTGT |
AAAAGCTTTT |
TAGTTTGATG |
TAATTTCATT |
|
10321 |
TGCATATTTT |
AGCTTTTGTT |
TCCTGTCCTT |
TTCTGTCATA |
TCCAAAAATC |
ACTGTCTAGA |
CCAATGTTAT |
GAAGCTGTTC |
|
10401 |
CCCTCTGTTT |
TCTTCTAGTA |
GTTTCACAGT |
TTTGGTTCTT |
ACATTTACAT |
ATTTAACTCA |
TTTTGAGTTT |
ATTTTTGTAT |
|
10481 |
ATGTTTAGAG |
ATTTTTATTC |
TTCTGCATGT |
GGTTTTACAA |
TTTTCCCAAT |
ATCATTTATT |
GAAGAATTTG |
TTCTTTCCCA |
|
10561 |
GTTGTGTGTT |
CATGAAACCT |
TTGTTGAAAA |
GTCAAATTAA |
TGTAAATAAT |
TGGGTTTATT |
TCTGGGTTTT |
CTGTCCTGTT |
|
10641 |
CATTTGCTCT |
CTGTTTCTAT |
TTTTATGCAA |
CTATTGTGCT |
ATTTTGATGA |
CTGTAGTACT |
TTGTAGTCTA |
TTTTGAACTC |
|
10721 |
AGATAGTGCG |
ATGCCTGCAG |
CTTTGTTCCC |
TTTACTCAAA |
ATTGCTTTGC |
CTATTCAGGG |
TTTGTTTTTT |
TGTGTGTGAT |
|
10801 |
TCCATATAAA |
TTTTAGGATT |
TGTTTCTATT |
TTTGTAAAAG |
CTGCCATTAG |
AATTTTGATA |
GGAATTGCAT |
TGTATCTTTA |
|
10881 |
GATTTCTTTG |
GGTATTAGGG |
ACATTTTAAT |
AATAGTAATT |
TTCCAGTCCA |
TCAACTCAAA |
ATACATTTCT |
ACTTATTTTT |
|
10961 |
GTCTTCTTCA |
GTTTTCCCTA |
TCAATATTTT |
ATAGTTTTGA |
GATTTGTTAT |
TATTGCTGTT |
ATTTTTGAGA |
CAGGATCTCA |
|
11041 |
TTCTGTAGCC |
AAGACTGGAG |
TATAGTGTCA |
CAATTATAGC |
TCACTATAAT |
CTCAAATTCC |
TGGGCTTAAG |
CAATCCTCCT |
|
11121 |
ACCTCAGACT |
TCCAAGAAGC |
AAGGACTATA |
GACACATGCT |
ACTATGGCCA |
GCCAACTTTT |
TAAATTTCTT |
GTAGAGACAT |
|
11201 |
AGTCTCACCA |
TGTTGATCGG |
GTTGAAGTTT |
TATACTTTTA |
CGTGTACTTG |
TTTTTTACCT |
ACTCGGTTAA |
ATTGATTTCT |
|
11281 |
AAGTATTTTT |
GCAGCAATTT |
TAAATGGAAA |
TTTATTTATT |
TTTTAAAGAT |
GGTTTATTGT |
TATACAGAAA |
CACTACAGAT |
|
11361 |
TTTTGTATGT |
TGATTTTTTT |
TATCCTGCAA |
TTTTCTTGAA |
TCTGTTTATT |
TGTTCTAAAA |
GATTTTTGGT |
GGATCCTTTA |
|
11441 |
GGGTTTTCCG |
TATATAAGAC |
CATTTCATCT |
TTAAACAGGC |
ACAATTAAAC |
TTCTTCCTTT |
CCAATTTTGA |
TGCCTTTTAT |
|
11521 |
TTCTTTTTGT |
TGGCGAATTG |
CTCTGGTCAG |
AACTACGTTG |
AATGGAAGTG |
GTAAATGTGA |
ATATCTTTGT |
CTTCTTCCTG |
|
11601 |
ATCTTAGAGA |
AAGGGTTTTC |
AACTTTTCAC |
CATTGAGTAT |
GATGTTAGCT |
GTGTGTTTGT |
CATATGTGAC |
TTTTTTTGTT |
|
11681 |
AAAAACTCTT |
CAATTTTATT |
GCTTATTATA |
TTTCTTCACA |
TATCATTTAT |
TCAGTCAACA |
CTATATTAGT |
TTACTGAGCA |
|
11761 |
CACAAATAAA |
TAAAACAGAA |
GCCCAGAACT |
CAGGTAGTTT |
GGATATCCCA |
CACACTAATC |
TGTGTACTGT |
TTGCAAATCA |
|
11841 |
CACTGTGTTG |
CAACATCTGT |
ACCTGATGTT |
GCAAGACTAA |
CATTTTTGCT |
ACCTCTTCTC |
AGAAGCCTTT |
GTGATCTCAC |
|
11921 |
CTGTTGGAAT |
GCACTAATGT |
TTTCTGAGCC |
CCTTAAATAT |
CTTGTCTACA |
TTCTTTTAAG |
AAGCTCTTCA |
CCAACTGTCA |
|
12001 |
GGTAATGTAG |
TTTGATGAAT |
TAAGAATGGG |
GGCTCTGGAT |
TCTGAACCCC |
TAGATTTCAA |
TTCTTGTTCC |
CAGTTACTAT |
|
12081 |
ATACTCGGTG |
TTCTTTTACA |
TTATTTGAGT |
CAATTACTTA |
TTATCTTCCA |
TTTTCCATAT |
AAGAGAGGTT |
AATATATGTT |
|
12161 |
TTATATGGAA |
TTTTTGTGAA |
ATTTCAGTAA |
TGCACTTGGC |
ATGATGAGGG |
CTCAATGAAT |
ATTAACTATT |
TTAACTGAAC |
|
12241 |
CATATCATGA |
TTAACTATAT |
AGACTATGGT |
GAAAAAAACA |
AGATTTGAAT |
CCTAATTCAT |
GTGATGTGAC |
ATAAGTTATT |
|
12321 |
ATTTAAATGG |
TGAATATAAA |
ATAGGGAATA |
TAATAACTAC |
CCCACTGGCT |
TATTGTGAGG |
GTCCAGTATA |
TTAACATTTG |
|
12401 |
TAAAACCTTT |
GGTACAGTGA |
TATGTAAATG |
ATAATGATGA |
TTATAATAAT |
GATTTAAATT |
GTTTTATATG |
CATTCATTTT |
|
12481 |
TTATTTATAA |
TAAGTACATG |
GGAGATATTA |
CCCTTTACTA |
AGTTAATTTA |
TATTATGTAA |
CTTTTTTCCT |
GGTTTGTAAT |
|
12561 |
GTCTAATGTT |
TTTCTCATAA |
TAGCTGCCCA |
ATAAGCACGT |
ATGAAAATAT |
TAATTCAAGA |
TAACCCAGAC |
AATGAGGCTG |
|
12641 |
GTGCTTCTGT |
GCCAAAGCTT |
TTGTGCAATG |
TCCTGACATG |
ATTTCTTTAG |
ATGTCATTTT |
CTGTCAGCAC |
TATCCTTACA |
|
12721 |
TCTACATGGA |
TTGTATAATT |
ATCTTTGTAG |
CATTGATTGA |
GAATTGATAA |
GATATCCAGC |
ATTTCTGTGT |
ACAATCTGCC |
|
12801 |
GAAATCATAT |
CTGTTGTATT |
GAAACAAAGG |
ATGTATTACT |
TTGGTATCTA |
TATTTCCTTA |
TAAATATTCA |
AATTACTCTA |
|
12881 |
AGGAGTAATA |
CATTAACATG |
GTGTCAAATT |
AAACTAATCC |
ACCACACTGG |
AAGATTAGGA |
ATCAGGTTAC |
TTTCAATTTT |
|
12961 |
AAATTTTCAT |
TGAGAACAAG |
ATTTGAAAGA |
ATTATAAATA |
TGGATGCACT |
CATCCATTTA |
TTCTTTAATT |
TATGTATTTA |
|
13041 |
GCAAGCATAT |
TAAGTACTTT |
TAAACATTTT |
GAATACAAAG |
ATGTGGGTAT |
AGGATGTAAG |
TTAAAAAAAT |
GCAAATTCAA |
|
13121 |
AGATATAGTT |
CTTTCACCAA |
GAAAACTAAA |
TACAGAAAAG |
AGTAAAAATC |
ATATAGGAAG |
TAAAAATCTA |
GTAGGAAGAA |
|
13201 |
TTTATATTCT |
AGACAAGAGC |
ATTGACTTTC |
CCGGGAATAT |
ATATTTTAGG |
CAGATCATTA |
TCACTATGGG |
CCGTGAACCA |
|
13281 |
GTAAAAGAGA |
AAAATGAATA |
CAGTGGATGA |
CCAGGAAGTT |
TGCATTAGGT |
CCAATGCCAC |
AGAAGGAAGT |
TGAGAAGCTA |
|
13361 |
AAAGAAAAGA |
AAAGAAAAAA |
GAACAAAAAA |
GAAAATAAAA |
AGTATTTAGT |
GGCAATAAAT |
TGTTAAACAA |
CCTGGTAGGA |
|
13441 |
ATATGATGAA |
TGACAGAACT |
CTATAGGTAC |
AAGAAGACAG |
ATGGTGAAGT |
AGGACATACT |
TTCAGAAGTA |
TTTCACATTA |
|
13521 |
TAGAACTATA |
TCTAAAGTGA |
GGGTGAAACT |
CTTTAAGCTG |
TGCCCATAGT |
TAAAGGAATC |
TTTCTATTTC |
TAACAGAAGG |
|
13601 |
CAACCACAGA |
AAAAAGCCAC |
TTAAGGTGTT |
GGAATCCCTG |
GGCAAAGATT |
TCCTCACTGG |
TGTTTTGGAT |
AACTTGGTGG |
|
13681 |
AACAAAATGT |
ACTGAACTGG |
AAGGAAGAGG |
AAAAAAAGAA |
ATATTACGAT |
GCTAAAACTG |
AAGACAAAGT |
TCGGGTCATG |
|
13761 |
GCAGACTCTA |
TGCAAGAGAA |
GCAACGTATG |
GCAGGACAAA |
TGCTTCTTCA |
AACCTTTTTT |
AACATAGACC |
AAATATCCCC |
|
13841 |
CAATAAAAAA |
GGTAAGACTG |
GATTTTTTAC |
AATGAATGTC |
TCAATTTTCC |
CTAAATCTGT |
TTAACTCCAA |
GGCCTAAGCA |
|
13921 |
GTGTCTTCTG |
TGATTCCCCT |
ATCTTTCCCT |
TCCTAAACTA |
TCATTTTCAC |
TAAACCTATC |
TTTGTCCTTT |
TAGAGACCAC |
|
14001 |
TTCCCTTTTG |
TGGGGTGGAA |
TCCAGTTTAC |
AATCAGCTAA |
AAGGCTGAGT |
CCTTGTGTTC |
AGACTGTGTA |
CAAAAATAGT |
|
14081 |
TAATAGTTCA |
CACCTTGTAG |
TAAGGGACAC |
ATAGAACTAA |
ACCTAGATTC |
TGTCACCTGT |
GACCTATGTG |
ACATCCTGTA |
|
14161 |
AGTTGCTTAA |
CTTCCCTAGA |
TCCTTAGTTA |
TTAGTCTTAC |
CATCTGTGAA |
ATGAAGACAA |
TTCCAGTACT |
TTCTCACAAG |
|
14241 |
ATCGTCTAAG |
CCTAGAAACA |
TTATAATGAC |
AGGCACCACA |
CGCCAACAAC |
TCTCAAGATA |
TTAGCTCTCA |
TCCGGAACTC |
|
14321 |
TCTCCTCTGA |
ACTCCAGGAT |
CATTTAGCTC |
TAGCAACATA |
TTCAACAGGT |
CTACTTGAGT |
GTTTTGCTGG |
CATCACAATA |
|
14401 |
CAAATACAGC |
TAAAATATAC |
ACTTTGTTCC |
CCAGAACAAA |
ACTGTTGCAT |
TTTTATTCCC |
TTTTCATCTC |
AGTAGACCGA |
|
14481 |
AACAACATCT |
ACCAAGTTTC |
TCCCACCAGA |
ATGCAACTGG |
TTTCTTCACC |
AATTAATAAC |
AGTAATCAGT |
AGTTTTCTTG |
|
14561 |
GCACATAGCA |
GATGCCTAAA |
TAATGTAGGA |
TGAGTAAATA |
AATAAAGTAT |
ATGCATTCAA |
TAAATACTAG |
TTTTCATAAT |
|
14641 |
TATTATGTGG |
ATGCTATGAA |
CTAGACTTTT |
CCAGTGCTTA |
CTTACTTCTG |
CGAATTACAA |
AATATGATAA |
GGAGAATCTC |
|
14721 |
CATAAAATGT |
CTAAAATTTT |
AAAACTTCTT |
TTTGGAACTT |
TTGACCCAGA |
TTGAATTACG |
TATTATTAAA |
GGTTAAATAT |
|
14801 |
TCTCATATTG |
AAGTTCACCA |
GAGACAGACT |
CAATACCCCC |
CAGAATTTAA |
GCTGAAATCT |
TGAGCCATGA |
AGTATTACAG |
|
14881 |
ATTACCAATA |
ATGATAAATA |
GTGATAAACA |
AAAGGAAATA |
TAAATTGTTG |
AGACCTCACT |
ATATCAAATG |
AGCTTTTTCA |
|
14961 |
ATCAGCACTC |
CTCTATGAAG |
AAGGGGTGTT |
CCTACCAACA |
GGGAGCACAT |
GATAGTATGA |
TAGTTGTCCA |
AGATTATAAG |
|
15041 |
AAGGTAGCAT |
TCTCATTAAT |
ATTTAAACTG |
GTCCCTTTGC |
AGGTTTTTAG |
TTTTTTCTCA |
AACCTGGATG |
GCATGGAAAC |
|
15121 |
AATCTCCATT |
TTCAAAAAGT |
CAGTGATAGT |
GCAACTAATG |
GGAATTAGAA |
TAGAAGTAAT |
AGAGGCTTCA |
GAATGGTTTT |
|
15201 |
AGCAAACCCA |
GATATCACAA |
TGAGCATTCA |
AGTCTAAACT |
GAAGTAATCT |
ATCTGATTAG |
CAGAGGCTGT |
GGCAGGAATA |
|
15281 |
AGGCAGCGGC |
AACCCCTCAC |
AGGAGGGGTC |
TAGTGTCTCC |
CTGGGCTCTA |
TCTGCAGTTG |
GAGTCTCCAG |
AGCAATCCCA |
|
15361 |
GGAAACTTTA |
GGTACACTGC |
CAGTGTACCT |
AGAGTGTATC |
CAGCTCTCTT |
TGGGCAGCAG |
TCTGCAGTAT |
AATATGTACT |
|
15441 |
ATCTTCTAAT |
GAAATGATTT |
GCTTTCATGC |
TAATTTTATT |
ATTGGATGTA |
AGATAGAAAT |
TCTATCTAAT |
TTCTAATTTT |
|
15521 |
ACCTGAAAAC |
ACTGTATCTC |
ACACACACAC |
ATAATGATCA |
TTAGGAGATG |
ACTAAGTTAT |
GAAGTTCTCT |
AAACCTGTAA |
|
15601 |
GTGAAGTGGA |
AACAGGAAAC |
TTTGGATTAG |
AAAACATACC |
CTCTGACCAG |
GGAATATCCA |
GGATCCAGCA |
TGTCTTCACA |
|
15681 |
TTGGCAGAAT |
TTTCTGAAAT |
AGGACCGAAG |
GTCATATATC |
ACTGTGTAAT |
CTATGAAAAG |
AGATGCTCAG |
AAGGTTTGAT |
|
15761 |
ATTCATACAC |
ACTCTTACAA |
CTTGTTACAT |
CTCCAGAGCT |
CAGACTGGCT |
GGCTTTACAA |
ATAGCTGGCT |
TTACAATTTG |
|
15841 |
CACAGGGATA |
ATTGAAGTTC |
ATTTCTTCTA |
GAATCATTAA |
AAATTAACAG |
TAAAGTTGCT |
AAAAAAATAA |
TGCCTTGAAA |
|
15921 |
GTACAAGATT |
CAATATTCTG |
TGCTTTGGTG |
TATGTATGTA |
TTTATCTGTA |
TGTGTAGTGG |
GGATTAGGAG |
GGGACGATTA |
|
16001 |
CTCCAAAATA |
GGATTTTGTT |
CCATCCTGTA |
TGGGATAACT |
ATTAAGCATT |
TGGCTTGTGG |
CTAAAAATAC |
ATGTTAAAAT |
|
16081 |
AATACTTTTT |
GTATGTTATG |
TTAAATAAAT |
GTTATTAGAA |
TTAATTTTAC |
CTGTTTAATT |
TTACTTTTTA |
CATGTGATAG |
|
16161 |
TAGAAATTAA |
ATATTGGACA |
TGGAACACAC |
ATTAAATTTG |
TAGTAGATAG |
TGTTCTGACA |
ACTATTTACT |
CAGTATACTC |
|
16241 |
TTGCACAGAC |
ACAATAGAAA |
GTCCACACAG |
ATAAATGAGT |
ATCCTGGAGT |
AAAACCTTTG |
GAAAAATCAA |
ATTCTTTTGA |
|
16321 |
CGGTATAAGG |
AAAGGCCAAA |
TTTAACCCCA |
ACATCATTGA |
CATGTTTTCC |
CCAGAATGAT |
CAGAATATAT |
GATTACATGT |
|
16401 |
TTGGGTGGAT |
CTGCTTTTCT |
ATCTTTTCCA |
GTAACAATAC |
ATCTCCTGAT |
GTAGAATACT |
AGATATGAGA |
TACAACTAAA |
|
16481 |
ACCCCTATAT |
GTGAAGAAAT |
CTTCCCAGGA |
CGTCTTCTCT |
CTCGATCTTC |
TTAGGTGATA |
AATTGGGTCA |
CAGAGGCAGA |
|
16561 |
AATCACAATT |
TATGTTCTGC |
AATATCCTGC |
AGCTCATCCG |
AATATGGAGG |
CTGGACCACC |
TGAGTCAGGA |
GAATCTACAG |
|
16641 |
ATGCCCTCAA |
GCTTTGTCCT |
CATGAAGAAT |
TCCTGAGACT |
ATGTAAAGAA |
AGAGCTGAAG |
AGGTGCTATG |
CTATCTATAT |
|
16721 |
GAAATAGAAA |
AAAAAGAAGA |
GATATCATTG |
CTTTCCTTCA |
GTGCACCATT |
TCTTACAGCA |
CTAAATGATT |
GGGGGTGGGG |
|
16801 |
ATGACAGTAA |
CCATTTTCAA |
TAATGCTTTT |
ACTAAGGGAA |
AGATTATGTG |
ACTTCACAAT |
GATACCAATC |
CTTTCTCAAT |
|
16881 |
CCATGATGCA |
GATCATTTTA |
TCATGAGTTG |
AAAGAAAATT |
GGTATTTCTA |
TTGCTCCTGT |
ATTTATTCTT |
GTAATTATTT |
|
16961 |
GGATTTTATG |
GCAATTGTAG |
CATTAGCCAT |
GGAATAAACA |
TATTTGGAGG |
ATAATATAGC |
TGACTTGTAA |
TTGGTTGCAC |
|
17041 |
TCTACTTGAA |
AAGTCTAGAC |
ATGAAGGATA |
CTTGGGAAAT |
ATAATTAAAG |
CTTGAAAAAC |
ATTATAAATT |
TATGTGTTAA |
|
17121 |
AAATAGTAAC |
AAAATAGCTA |
TGCTTCCGAA |
GGCAAAGACT |
TTTGCTGTAT |
TCATTTTTCA |
CTGGAGTCAA |
CGACAACATC |
|
17201 |
TCGTTTTGTA |
TGAAATTTGA |
CCTGAACTTT |
GAATGCTAAG |
AAAGATTGGA |
GTAGGTGAAG |
AAGAAAAGGG |
AGAAGAAAAG |
|
17281 |
GCATAGGAAT |
TATCTAGTTT |
CCTCAAGATT |
CTTAATAACA |
ATTTCAGATA |
TGTCCGGTTC |
TTTCCCTGGG |
TTCTTGAGAG |
|
17361 |
AGAGAAAGTC |
AGTGTCTTTT |
GATACAAGTT |
AGAGCAGAGA |
GGAGCTGCAT |
GAAGACTTGA |
AAAAGCAACA |
CTGATAGGCA |
|
17441 |
TAAGGAGGCT |
GAAAGGAGAC |
TTGAGTAAAT |
TAAATTTATT |
GCATCTCCAT |
ATCCTGCAGA |
TCTATCCAAT |
AAAGGAGAGA |
|
17521 |
AACAACCGCA |
CACGCCTGGC |
TCTCATCATA |
TGCAATACAG |
AGTTTGACCA |
TCTGCCTCCG |
AGGAATGGAG |
CTGACTTTGA |
|
17601 |
CATCACAGGG |
ATGAAGGAGC |
TACTTGAGGG |
TCTGGACTAT |
AGTGTAGATG |
TAGAAGAGAA |
TCTGACAGCC |
AGGGTAAGAA |
|
17681 |
TCCCTCAGCC |
GCCACAAACA |
CATACATATT |
CAAGACACAT |
CCTTCTAATA |
ACTACCTAGC |
TTCAAAGAGC |
TCAACAAGGT |
|
17761 |
TTAACAACCT |
TTGGGTGTGT |
GTGTGTGTGT |
GTGTGTGTGT |
ATACAAAATA |
AGAGTACTAG |
ACTGGTAAAT |
CTATGTCTCT |
|
17841 |
TTGGTCCTCC |
AAATATCCTC |
AATTCTGGAA |
AACTAGACTA |
AACATGATTG |
ACACGTGTTT |
TCACATTTCT |
TATTGAATTC |
|
17921 |
CAAAATCATG |
TGATTGGGAT |
GCAGCCCCGA |
AAATCCCCAG |
AAAATTGTAG |
AGTAATGAAT |
GTTAAATGGC |
AGTATACTTA |
|
18001 |
TAAAACAAAT |
ATTGAATCCT |
AAACTTGGTG |
CTAAGAGCTA |
TTCCTAACGT |
TGGGAATAGG |
TCTGTAAATG |
AGACAGGAAG |
|
18081 |
TTCCCAGCCA |
GCATTCATCT |
AGGTTACAGT |
AGAGAGAAAC |
AGTGAAATTG |
TAAGAAAAAA |
GACAACTTCA |
AGCACCAGGT |
|
18161 |
GTGCATATGT |
GTGTCTACAA |
AACAGCGACA |
AGACAGCCAA |
AAGTAAGTAA |
AAAGAAAATA |
AAAAGGAAAT |
ATGAGACAGA |
|
18241 |
ATTGTAGGGT |
GGGGAGCAAC |
GTTTTTGGGT |
TGGTTGGAGA |
TGGCTCTGGA |
AAGACATGAA |
TGCAGCGCCT |
TCAAAGTAGG |
|
18321 |
AGACGCCACC |
TGTGAAAGAG |
CTGAGCTGAA |
AATGAACCTG |
GCACACGAGA |
AGCACAAAGA |
GAAGACCAGT |
GTGACTAGAG |
|
18401 |
GTTGAAGGAG |
AAGGAACATA |
GTATGAGGGT |
GGTGTATGGT |
CAGGCCAGAA |
GTTTGATTCT |
ATTCTAAGCA |
TAGTGGGATG |
|
18481 |
GATTTTACAA |
AGAACATGGT |
GTGTTGCATT |
TATAACACAT |
GACTTGCTAG |
GTAAGGAGAT |
AGAAGATTGA |
GATGGAAAAG |
|
18561 |
AAAAAGTAAC |
ATGAGTAACA |
CATAGCAATA |
TACAATATAC |
TAAGAAGACA |
GTATGTCAGC |
AGGAAGAGAA |
AATGGGAATC |
|
18641 |
CACGGCCCCA |
TAAAGAAGGA |
AAAATAAAAC |
CATTAAACAG |
CTGTCATGAC |
TGAGTAAGCA |
CTAAGTGAAG |
CACCACGACC |
|
18721 |
TGGATGTTAC |
ATATGTTTCT |
TGTTTCGCTC |
ATGGTAAATC |
TAGGAGTCCC |
CTTTAATTGT |
GATGCTTCTC |
TGACTGAAGT |
|
18801 |
TAGACATTGC |
TCTTTTACAG |
GATATGGAGT |
CAGCGCTGAG |
GGCATTTGCT |
ACCAGACCAG |
AGCACAAGTC |
CTCTGACAGC |
|
18881 |
ACATTCTTGG |
TACTCATGTC |
TCATGGCATC |
CTGGAGGGAA |
TCTGCGGAAC |
TGTGCATGAT |
GAGAAAAAAC |
CAGATGTGCT |
|
18961 |
GCTTTATGAC |
ACCATCTTCC |
AGATATTCAA |
CAACCGCAAC |
TGCCTCAGTC |
TGAAGGACAA |
ACCCAAGGTC |
ATCATTGTCC |
|
19041 |
AGGCCTGCAG |
AGGTGGTGAG |
TGCTGAGACT |
GAACATCTAA |
CAGTTATGAA |
GGTGTATGCA |
GAGGATTGTG |
ATGTTTGGTT |
|
19121 |
TATATTTAGG |
GGCAACATTC |
TTAAACCTCA |
TCCAGTGTAA |
ATAAAGTACA |
TTGAATTCTA |
AAGAAACTCT |
ACCTAAGGGT |
|
19201 |
CTGGTATAAC |
AAGAAATTGT |
CTCATCAAAA |
TTAGTGGAGA |
AATTTCTGTT |
CAATTTTATC |
CACAGTAAGT |
GGTGAAGGAG |
|
19281 |
ATCATCAGAA |
TCCCTAAATC |
AAAGTTAAAC |
AGAAATACTC |
AAACTTTGGA |
ATGGAATCAT |
TTTCATGATA |
GCTTGATTTG |
|
19361 |
TAAATGTTTT |
ACAGAAATTT |
TGACATTGTG |
TGGTTTGAGA |
AGAATTTCAT |
TTGAAACTGG |
GGCCATTATG |
TAAAACAGCA |
|
19441 |
TCCCTTTTTC |
TTATAATTAT |
TGAGGGGGAA |
ATTAGTAAAG |
AGATCAGGGG |
ACTGTAGAAT |
GTTGCAGTGC |
CACTTTGCTC |
|
19521 |
CAAAGATTCA |
ATTGCCTCAT |
GGCTGGCTGA |
GGATGGTGGC |
TCATGCCTAT |
AATCCCAACA |
CTTTGGGAGG |
CCAAGACAGG |
|
19601 |
AGGATGGCTT |
GAGGCCAGGA |
ATTTGAGACC |
AATTGTCTGA |
TAGCTCTTGG |
GAGCTATTTT |
TCAAAAGAAA |
ACAGATTTTT |
|
19681 |
TTTCTAGAAA |
ATGGTAAATT |
CAAGATGATT |
TCACTATCAG |
TAGGCACATT |
GTTGAATGAC |
ACTGGAGAGA |
AAGAAAAGTG |
|
19761 |
GTGTGTGTGT |
GTGTGTGTCT |
CTCTCTGTGT |
GTGTTTGTAT |
GTGTGTGGGT |
CTGTATGTAT |
GAAACTAGTA |
AGAATGAACA |
|
19841 |
TTCAAAAAGA |
ACAAGGTGGG |
CAACTGTGAC |
AGCCATTCTG |
TGGGAGGCAC |
AGCAGTGTGC |
AGAAAGTTAA |
TGTCTCCATA |
|
19921 |
GCAAACCGTG |
GGGAACTGTG |
GGTCAGAGAC |
TCTCCAGCAT |
CCTTGGAAGT |
GGCCTCTTCA |
CAGTCATCTG |
AGAACCTAGA |
|
20001 |
GGAAGATGCT |
GTTTACAAGA |
CCCACGTGGA |
GAAGGACTTC |
ATTGCTTTCT |
GCTCTTCAAC |
GCCACGTATG |
TATCTTTCAG |
|
20081 |
TGGCAGTAAG |
GGATTTGTGG |
GCCTGAGGCC |
ATCTTTGAAT |
GAATCTAGAA |
AATCAAGAAT |
CCCTATGAAA |
CAATGATCTG |
|
20161 |
ATAGAATGTT |
GTGTGCTCTC |
CACATATTTT |
ACATGATCTT |
ATGTGTGCCG |
TGAGAACAGA |
TTCCTAAAGC |
AACCCGATAC |
|
20241 |
ATGGAAACCC |
ATTCACCACT |
CACCATTTAA |
ACAGATGATG |
AATTCTGTTT |
TTTTTATTAA |
GCCCATTTAA |
CATTTTACAT |
|
20321 |
AGTGTTTTTA |
TGGATTCCAG |
GAATGGCTTC |
TCTTTCTCAA |
ATGATCAACT |
TCAAGTCTTC |
TTTCCATATT |
TCACATCTGA |
|
20401 |
TTCTACAATG |
AGCAGTGCCA |
TTGCATGCCC |
TGCTAGAACT |
GTGGATACCC |
TTTAAAACAA |
GTAGAAAATG |
ATAGGGTGGG |
|
20481 |
GCTGATTAGG |
TCTAATCTCA |
GGGAACACTG |
GTTAGTATTT |
CATGTCTAGG |
TAATTATCTT |
AAGGAGCGTA |
CATTTAACTG |
|
20561 |
TTTTTGATTT |
GTATATTTTT |
AAATCTTATT |
TTTTAAAACC |
ACTTTATTGA |
GGTATGATTG |
ACATACATAA |
TGTTACATAT |
|
20641 |
TTAATGTATA |
CAACTTAATG |
AGTTTGGAGA |
TTTCTATGTA |
CTCCTGAAAT |
CATCACCACT |
ATCTATGCCA |
TAAACATATC |
|
20721 |
TCTCTTCTCC |
AAAAGATTCT |
TACACTTCTC |
TGTTTATTAT |
TATCATCATT |
CCGTGACTGC |
GTGTGAGAAG |
TATACTTAGC |
|
20801 |
ATAAAATCTA |
CTCTCTTAAC |
AAATTTCAAG |
TACATAACAC |
AATGTTGGTT |
ACTACTGGCA |
CCACCCTGTA |
CAATAGATTT |
|
20881 |
TTATCACTTT |
TTTCAGCTTC |
TATCACTGAA |
ACTTGTCATG |
TGTTCATCTA |
TTTCTATTAT |
ACGGTGAAAG |
ACAGTGTGGC |
|
20961 |
ATAATCTGCA |
AACAACTTTG |
GAGCCTGGTG |
GCAATTTTTT |
GTTGCTTACT |
CACTGTGTGA |
ACATGGGGAA |
GTTCCTTCAT |
|
21041 |
CTTTCTGTGC |
TTCTATTTCT |
TCCTCTGTAA |
AGTGGGATAA |
TTCTAGTTAT |
TTCTCAAGCC |
CCTATAAAAG |
CTGAGAGAAT |
|
21121 |
GAACATGAGT |
TTTGTAGTAG |
AAAGCCAATC |
CCAAGAATCA |
AAATTTCTTC |
AATACACAAT |
CTCTTGCAAT |
GCTTACCAAC |
|
21201 |
TGCAACTTTT |
GATCACCTTT |
TGCTAGGTTT |
TCTGTTTACG |
TTCTGTGGAA |
AGTAGGTAAA |
TGTCAGGTTG |
TAAGTGCTTC |
|
21281 |
CTACAAATCT |
GTAAAGATAA |
TTCCCAAGCT |
ATGCTTTTCT |
TTTTAAAAAC |
ATTCTCAAAA |
CAAAAATATG |
AACAAAAACA |
|
21361 |
TAGTGAAAGT |
CATAGCCCAA |
GGCATACCCA |
TCTGTATCAT |
TATAGACAAC |
GTGTCCTGGA |
GAGACAGCAC |
AATGGGCTCT |
|
21441 |
ATCTTCATCA |
CACAACTCAT |
CACATGCTTC |
CAGAAATATT |
CTTGGTGCTG |
CCACCTAGAG |
GAAGTATTTC |
GGAAGGTAAG |
|
21521 |
TGTCTCTTTT |
CTAGTTACTC |
ATTTATTTCT |
TCAGGAAGAA |
TTTGTCATGA |
TTCACTTTTT |
ACTTCACAAT |
GACAATTTTT |
|
21601 |
GTCAGGGAAG |
TGAAAGTAGA |
GAGGTACCCA |
GTTTCTGTCA |
TTCAGTTGTT |
TAAAATATGG |
CTAAGGAAAA |
GACAATTCCA |
|
21681 |
ATATATCCCA |
GCAGAAGATC |
AAAGTAAAAT |
AAAATAATAT |
CAACCATAAG |
CTTTATGTTA |
TGGAGCGTAA |
GTTCTTAAGT |
|
21761 |
TTTAGAGAAG |
GAAAAATATT |
TTGAAATAAT |
TTTTATTTCT |
TAATTTATTA |
AATGAATAAA |
ATCTGGGTGG |
TCTGCTAGGT |
|
21841 |
CATGGATTTC |
CTCCTGGTGA |
CAGAGGGGTA |
AATGAGGCCT |
ACATGACGTA |
ATCCTATCTA |
GGACTCACAT |
TTTCGTGGGA |
|
21921 |
GATATGGATA |
CTGAAAATGT |
GGGTTAACAA |
ACAAATATGT |
GCTTACAGAT |
TGTGATAGGA |
TCCATAAAGA |
CATGTGAGAG |
|
22001 |
GGAACAAAAA |
AGAAGTCATT |
CTTTCAATAA |
AAAAGTGCAG |
AAGGAAAGGT |
TTGCTACTTC |
TTGCCCAACT |
TGGGACATTC |
|
22081 |
CTTATTCCCA |
CTACTTCCTA |
TGTTATTTTT |
CTCCATAGCT |
CGTACATCTA |
CCCACTCAGC |
AAATATTAAT |
AGTTTATTTA |
|
22161 |
TGTGTCTGGT |
TTTTTACTTG |
TATTTACTCA |
CTAACATGCA |
AACTTCGTGA |
TGGCAGGGAT |
TTGCTCAGCA |
ATTCAACAAA |
|
22241 |
CCTGGCACGT |
AGCAGATATT |
CAATTAATAA |
TTATTGAATA |
AATACATGCA |
TAAATACACA |
GATAAATGCA |
CCCTCTTGTT |
|
22321 |
TAAAGAGAAA |
ATGGGATTGG |
TATTAACACA |
GAATAGTATA |
ATTATTAATA |
AAGTAAAAAT |
TGTAGAGAAC |
AGTAAAACTC |
|
22401 |
CTGCGGGAAA |
AGAAAGATAC |
ACCTCTGGCG |
TTTATAGAAG |
AAAGCCATCC |
AGAACCAGCA |
CAGTCACTCA |
TTCCTGTAAT |
|
22481 |
CCCAGCACTC |
TGGGAGTCCG |
AAGGAGGGTG |
GAGTGGCTTG |
AACCCAGGAA |
TTTGAGGCCA |
ACCTGGGCAA |
CATGGCAAAA |
|
22561 |
CCCATCTCTA |
CAAAAAATAC |
AAAAATTAGC |
CGGGCATATT |
GACTGGAACC |
TGTAATCCGA |
GCTACCTGAG |
AGCTGAGATG |
|
22641 |
GGAGAATCGC |
TTGAGCTCAG |
GAAGCGGAGG |
TTGCAATGAG |
CTGAGATTTC |
ACCACTACCC |
TCTAGCCTGG |
ATGACAGAGT |
|
22721 |
AAGACCCTGT |
CTTAAAAAAA |
GAAAAAGAAA |
GAAAAGTAGT |
GAAATAAGAA |
GAAGGAGGAG |
GAGAAGGAGG |
AGGAAATGCA |
|
22801 |
GCATAAATTG |
AGACAGAGCT |
CCTGTGAATA |
GAGATCTGGG |
AAGTTAAATC |
TTTTAAATCT |
TCTTGGATAA |
GTGGGAGTTA |
|
22881 |
GACATTGTAC |
TTTCAAGGAT |
GTTCATAGAA |
AAAGGAACTA |
AAAATTCTGG |
ATTTAGGATA |
AGTAGACTTA |
CCAATTAGTT |
|
22961 |
GATGCAAAAA |
AACTACAAGA |
TCAGCTTGGT |
GGTGGAGATA |
TGAAAGTTGT |
TCAGTGTTTG |
GGTCTTAAAG |
ATAAGATACT |
|
23041 |
GGGGCTGGGC |
ACGGTGGCTC |
ACGCCTGTAA |
TCCCAGCACT |
TTGGGAGGCA |
GAGGCAGGAG |
GATCATGAGG |
TCAGGAGTTT |
|
23121 |
GAGACCAGCC |
TGGACAACAT |
AGTGAAACCA |
CGTCTCTACT |
AAAAATACAA |
AAAACCAATT |
AGCTAGGCGT |
GGTGGTGGGC |
|
23201 |
ACCTGTAACC |
TCAGCTACTT |
GGGAGGCTGA |
GGCAGGAGAA |
TTGCTTGAAC |
TCTGGAGGCG |
GAGGTTGCAG |
TGAGCCGAGG |
|
23281 |
TTGCACCATT |
GCACTCCAGC |
CTAGGCAACA |
GTGCAAGACT |
CCATCTTAAA |
AAAAAAAAAA |
AAAAAGAAAG |
ATAAGATACT |
|
23361 |
GGGATTAAAT |
TCTCCTTCAA |
TTGAGGAATC |
AGCCTTGGTG |
AGTGTTGAAA |
GTACAGAGTC |
CTTCCTTATC |
TGGTTTTCAT |
|
23441 |
GAATAGTTTT |
CAAGGGATAA |
CTTATTGTCA |
GATCTGTAGG |
TCAGAAATGG |
AAAATAGAGG |
AAATGAATGT |
TGAAAGACCT |
|
23521 |
TGGATTAGAC |
ATGAGGTGTT |
TATTTTGATG |
TAAAGCATAC |
AGTCTGACAT |
GGAGTGGCAA |
TTCTAAGAGG |
TAGGGTACAA |
|
23601 |
TGTTGAGGAG |
TTAGAATGCC |
CATGGGCTTG |
GTTCTATGAA |
ACCTGCAAGC |
TCACTTCATT |
CCAGGTGTTG |
TCTGGTACAT |
|
23681 |
GGTGAAAGAT |
GCTTTCTGAG |
ACTTGAAAAG |
AGTCGTATCT |
CATCTACAGC |
CTATTTTCTT |
TTTCAGGTAC |
AGCAATCATT |
|
23761 |
TGAAACTCCA |
AGGGCCAAAG |
CTCAAATGCC |
CACCATAGAA |
CGACTGTCCA |
TGACAAGATA |
TTTCTACCTC |
TTTCCTGGCA |
|
23841 |
ATTGAAAATG |
GTTAAGTATT |
GAGAGTTGTT |
GGTGGTATGT |
GAAATAAATA |
AGAGAGTGAT |
ATTGGTGGTT |
AAGTTCAATG |
|
23921 |
ACAAATGACA |
GCTGAGTACT |
TGGATGGTCA |
AATTGGTGTT |
TTTGTTGATA |
TAGTCTGGTG |
ATTATCTGCT |
ACTTCTTTCC |
|
24001 |
GACTTACATG |
TATTTGGATT |
CCTCCAACTC |
TACAATTAAT |
CAGGCAATCA |
ATCAATCAAT |
CAAGGAGGTA |
AGGAAAACCG |
|
24081 |
CAGCAGAATG |
TGATGATGAA |
AAACCAAGGA |
TAGTAATTAT |
TAAAATAGAA |
ACATGCTCAT |
GCTTCCATTA |
CTATTTATAT |
|
24161 |
TCATTTATCT |
CTCATAGTCT |
TTCTCTTTTA |
TTCCCCTTTC |
TTACACACAC |
ACACACACAC |
ACACACACAG |
AGAGAGAGAG |
|
24241 |
AGAGAGAGAG |
AGACACTAAG |
TAGCCAAACA |
TTGCATCAAA |
CCCTAAACAA |
AACAGAGTAA |
ACAAAGGAGC |
TAACTCTGGA |
|
24321 |
GAAAGCAGCA |
TTTTGATCCT |
CTGAGTGAGG |
ATGTCACAGC |
AAATACCACA |
TTACTGACAT |
CCAGATACCA |
TTACCAGATG |
|
24401 |
GTACAGAATA |
CATCCTACAC |
TGTAGAGTTT |
GTGTTGATCC |
AGGCTCTGGT |
TCTCAGACTG |
TTCTCACAAT |
GCAGATCACC |
|
24481 |
AATCACTCAG |
GGTTGGCTTT |
TGAATCTTCA |
ATCACAGTCC |
AGAAGTTCCT |
TCAAGCTCCC |
ATGTAACTTT |
TGTTATTATT |
|
24561 |
TTGACCAAAA |
TATTATAGAA |
TGGGTACATT |
GAGTCTGGAC |
TAAATGATGA |
CTTTCTTCAC |
TCATAATAGC |
TTTATTTAAC |
|
24641 |
ACTAGACTAT |
AAGACTATTA |
TCAATCTCCC |
TCTAAGATAC |
ATACTTAAAA |
TTATATTTTA |
TAGTGAAATG |
TATAAAGTTG |
|
24721 |
TTCTCAATAC |
TTCCAACATT |
TACCACATAA |
TTTTTACTCT |
TGGTTTCTGA |
CACTTCAGTC |
ACAATATTGC |
ATCATTTCAG |
|
24801 |
CATAACAGCT |
TTCAGTGCCT |
AATCCATCCA |
GTGGGGCTGC |
ATTTGGACAT |
TGAATTGTTT |
GTTGACTAAT |
ATTTGCCAAC |
|
24881 |
ACTAACTGTG |
CACCAGGTTT |
TGTTCTAGAT |
GCTTGGAATA |
TGCCAATTAA |
CAACGTAAAT |
AGATTTCTTA |
CACTCTGAAA |
|
24961 |
GCTTATATTC |
TAGTGAGTAG |
AAACAGACTC |
TGAAGACATA |
AAGTGGTAAA |
TATATCACAG |
GCCGGAGAGC |
AAAAAAAGAT |
|
25041 |
AAAAGGAAAA |
ATAAAGGAAG |
ACAAAGGAAA |
ACACAGAATG |
ATGGATGCTG |
TACTCCTATA |
GATATTTCAC |
TCAAAAGCTT |
|
25121 |
TTCTTGAAAT |
AATGAAATCA |
GAACAAAGAA |
TGGACAGAGT |
TGGGGAGTGA |
ATAATGTGGT |
TCTTATGCAG |
GAAAAGTGTT |
|
25201 |
CCAGCACAGA |
ATACAGCCAG |
TGCAAATGCC |
CTGGGATAGC |
AATGCACTAA |
ACATGTTTAA |
AGAACTGCAA |
TGAGACAGTG |
|
25281 |
TGACCAAAAG |
AGAACGTGAG |
TGGAGAAAAT |
GGCAGAGACA |
AATTAGGAGA |
AGCAGTGAGA |
AGCCAGATCG |
CGTGGTTCTA |
|
25361 |
TGTTATCACA |
TGGTAAACCT |
TTAAAAATTA |
TTATCTGAGC |
GAGACAGGAA |
GCCTTTCTAG |
TGCTTTAGAA |
AAAAGAAGTA |
|
25441 |
ATATGCTTTA |
AATTAGGTTT |
TACAAAGATC |
ACATTTTGGT |
GAATAGACTA |
AGATGTCACA |
GATGGAAGTC |
AAGGGAAGTG |
|
25521 |
GCAAGAGCAC |
ATGGAAGAGG |
ATGCAAGAAG |
AATCATGATG |
AGGGATGGGA |
TGAAGGCAGC |
AAGGGGTAAC |
CATCTTGACC |
|
25601 |
TTCTGTTTTT |
TCTCTCCCCT |
GCAGGAAGCC |
ACAAGCAGCC |
CAGCCCTCCT |
TAATCAACTT |
CAAGGAGCAC |
CTTCATTAGT |
|
25681 |
ACAGCTTGCA |
TATTTAACAT |
TTTGTATTTC |
AATAAAAGTG |
AAGACAAACG |
AA |
|
|
|
|
|
|
|
|
|
|
|
|
>ref|Gene_ID:837|CASP4|NC_000011.9:104813593...104839324 (-)
TACATAGTTTACTTTCATTTTTGACTCTGAGGCTCTTTCCAACGCTGTAAAAAAGGACAGAGGCTGTTCCCTATGGCAGG
TGAGTCCTTTTCTGACTAGGAGTTTGGGAGTAGGAACTTAGAAAACACTTGATTTATTGCTCTGAAATAAACACAAGAAA
GGAAGTGAGCCGATAGCACACATGTTGAATTCCTTTTCTTACTGATTGTGTGTAGTTTGAATCATGGGACCTGGTGTTAG
AGATATTGACGGAGGTCATATGTTTTCCAGATGTCTTTGAGCCAGAAAGAAGTTAATTCCTTTCTTTCAGCTTCTGGTAA
TCAAAGGGAGGGTAAAGAAAGCCAGAGGAAGTTATTTGTGTGAGACAATTCTAGAAGTTTCGAAATGCACTCTGAAATCT
TTCTTTTGATTCCAAATTAATTGCCCAGATCACAAACCTTTTTCGCAGAATCAGATCTGAGAGCCTCTGAATTGTTATCT
TCTTCGACATCTCTTATTGTGAATTACATTCTTGGTCTGTTTAAAGTGATTCAATTTTTTCCTCTTTCTCGTTGGTCCTG
ATACTGACTACTTTAATATAATATTTCATGGGTTAATATCACAGTTGTTTTGTTTTGCCGTTGTTATTGTTTTTAACTGG
TATCCTTCCCTCCAGGACTTAACTCTCCAATCCATTCTGCACACAACTTTTAGGTCACCTGTCTTATACACAGAAGCTGA
AAAAGCCTAAGGGATAGAGTTACTTAGGCAGCTAGTATTCCAGCAGGTCATAACGCTTCTTTGGCTTCATTCTCCTCACA
GGAAAAGGAAGAAATTGGACTAGATCAGTGAATTCTAAACCTTATAACATATCGCAGCAATCTGTAGTCATATAAAAAAA
GTCAGATGACTACCCCCTTCCTCACCGCGAATAGCTCAATCTTAAATACCCTGCAGGCATTTATTACCTTTGAAGATCGT
CACATAATTCTTATGAAACTGACTTGACATAGGTTTGTTCTATTAGGAAAGTTGACCAGTTAGTTAACACTCTCTGCTTA
TCTGCTAGTGATCTATTAATGTAATTAACTTTGCTCAGGGACATACAGTGGCTCCCTATTGCCTTTTCTCTTTTTTACTA
TCTGAACTTTCAGACAATTTTTTCTACCTTTTGAAACATGTGTATCCAGTTTTTCCATTAATCTTTGTAAAGCATGATTT
CAACTTCATAAAAAAATACTGTATTTACTTCACTCATATTACCTTGTTGTTGTTTCTTTACTCCTTTGATTCTCCCTATA
GAACAATTCTCTCCGGGGTTTATGTCTAACTTCACAACATTTAACTTAAGCTCTGGAATCAAGGGATCATTAGATAAAGA
TAGGGTAAATTGAAAGCCACTAGTCAAAAACAAGTCGTGGTTTGATAATTATAAACAACCAAATGTAGACAGCTATTATT
ACCTTAAACTCTTGAGGAATTGTATCCTGTAATGTGTTTAAGCATTACATCACTTTGCCTGGAACCAAAACTGTGGTCCT
GATAAGTTTTTTCCTCTAATTGATTCCTGCCATTTTTATTATCACTGCAGCTTTCATTCAGTGATTATTATAATAACAAA
AAATAATCTATAGTAACCATTTCTTTAAAAAATACTTACCATATGATAGCTAATTCATGCACTCTCTCTGATTTAATATT
TAACATCAATCAATACAGTTGTGCTATTATTTCCATATTGTAGTTGAAGGGGATACTTAGAGAATGCCTCCAAAATATGC
TTTAGGTCAAAAGTCTGTTGAGAGGAGTGGTCTCAGGTTGGCATGACTCTCAAACTCTGCCATTAATCTAACTTTCTGCA
AACATCTTCAAATACTTGCCCTGTCTCTGATCACTGCCACTTCAGTCCTGGCCTCACATTTCTATTCCTTCTAAAGCCCA
GCTCTCCCAGTTTTCTGGTTACACGAGACACCCTCAAGCCTTTGTGCTTTTTTCCTTACTGCTCTCTGCCAAAAGACCAG
CTCCTAGTTTTCCAGGGGACAAATTCCTACCAGTCCTTCAGGTCTCAGTGCCAAGCCCTCCCTTCTCTGGACAGCTGTAC
CTGAGACACACTTTGCTTATGCTTTTCTTGAGCTTCTGCTAATTATTTACATTCTTATAATATTTTTCATTTTACTTATT
TGCATATGTATTTTTCCACTTGACTGCAAACTTCAAAGTGTACAGACATGCTGCCAAAGTGGTACCCCCAATAACAGCAG
AGTAAGTTTCAAGAATTTATGCTCATTAAATATACCTGAATGGATAGGGGAATGAACATGCCTTCCTTCTGTTGAAATAT
CCAACATGCAACTATCATCTATTAAATGAAATCAAACTTACCTGGTTTGCTATTAAGAATTTGTAATCACCAGGTGGGTT
CACCTTGCCCACTGCTTAGACAGAGCCAATTTATCAAGACAGGGGAATTGCAATGGCGTAAGAGTAATTCACGCAGATCC
GGCTGTTCTGGAGAGGGTAGTGTTATTATTACTTAAATCAGTCTCCCCGAGCATTCAGAAATAAGAACGTTTAAAGATAA
TTTGGCAGCTAGGGGCTTGGGAAGTAGGAAGTGCTGATTACTCAGGTGGGAGATGGAATCATAGGGTGTCAAAGTGAGGT
TTTCTTGCTGTGTTCTCTTCCTGGGTGTGATGGCAGAACTGGTTGGGTTAGATTACTGGTTTGGGTGGTGTCAGCTGATC
CATTGAGTGCAGCGTCTGAAAAATATCTTAAGTGCTGATATTAGATTTTATAAAGTGATATTATCCCTGGGAGCACAATG
GGGACATTCCAATTCTAGGAGCCAGAGGCTGCATGTCCCTTACATTGTAATTTTTAGTCTTGTAGCTAATTTGTTAGTCC
TGCAAAGGGAGACTGGACCCCAGGCAAGAAGAGGGTCTTTTCGAGAAAAGGCTGTTACCGGTTTTGTTTCAGTCAAACCA
TGAACTGAATTCCTTCCCAAAGTCAGTTCGGCCTATGCCCAGGAATGAATAAGAACAGCTTAAGGGATAGAAGCAAGATA
GAGTTGGTTAGGTCTTATTTCTTTCACTGTCGTAATTACCTCAGTTATAATATTGCAAAGGCAGTTTCAATCCCTCTGTT
TGGGTTTTCTAATAGCTTAATCTTAAGGTGTAGGCTATGAAGATGGGAAAAGGCTGTCGATCACTCTGGCTTCTTCCTGC
TGACAGGAGACATAGTGGAAATTAGAGTGAACCCCAAGGTGAGAAGAATGTAACCACTTTGCAACTGTCTGAGCATACTC
ATGCAGGACTGGCTGGGCTTCCAATGCTTGCAATGCAAAAACATTAGTACTCTCCTCTGTAGTTTTGCTATAATATTTAA
GCCAACAGCCTCCTGTAAGGTAAATAACAAATCCTAGGATGAGGAGTACAATTCTCAATTTTAAAAGCAAAGATTGGAAA
GCATTAATTTGGGGACTTCTAATCCACAAAGAATTTAGGATTTAGTCCAAACTGTAGGAAAAAACTCAAACAAAACTAAC
AATGGGTATATTATATGTTTTCTTTTGAAGCATAATTTTTCTCTCCAGACCCTATTTTTATTAAAAGTAAATTATAATAG
AACTAATCTGTTTACCAAAATAAGCTTTAGTCTTACTGTACTTGGCCTGATTATTTGCATGAAGTGCAACAAGAATAATT
ATTTTTTATTTAGGCTGTTTTTTGTTTAAATTGGCTTTGATGGAACTCTGTTCCATGAGGAATCTCAGATAAGACTTTTT
AAGAGCCAATCCCAGCCATGCATTTGTACCCTTAAATACCTATGAGTTGGGTAAATTCCTCTCCTCTCAAGGTCCCAAGA
TAACTTGGAGCTCATGAACCTGTTAGAAAGTGATATTCTTTACTTACTACAGATCAAGAACCTTGTACAAGGACTCTGTG
TAGACAAGGTATGAAGCCAGATTCCCCAAGGGGCTTTTATTGGCTCTGTAAGTCAACTTCGATTCTTTAAGGGAAGAGTG
CCATTCCAGTCAAAGCCTTGGTAAAATAACCAATTTCTCCAATTGTGTCATGTTACAAAAGAAAACAGATTTTTATTGTG
CTTATGGAATTAACCATGCTGCCATAAATTGAGAATACTTACAAAGAGTTTCCAAATTCTGGAGAAATCAGGTAGAGAGA
AACAAATATGCTTCAAAATTTTTTCACAGGAGTGTATTTTACCTACTTGTTAAAAGTTGCAAATATCTCTAAAGAAATAA
GTTATCTTGACTGTGAAAACTGAAGGATTGGTGACATTTAAGACATCAGCTCTTCATGAGAGTCCTGGAAGTTTTGTTTT
TTTCCTCTATTCCAATAGCACAATTTTTAAAGTTATCTGAGACCTGCACTCAGAGTCCTATACCTGATTATAAACTGCCT
TTTGAAAACGACCAAAGCAAGACAAAATGTCTGTGGATGACAAAAGTCTATAGACACTATTAAAGCTATAATTGACTAGG
AATTTTGCTTACTTCTGTGGCATCCAACAATTTTGTATAACAATTATAATTACTAATAATGTACAGTAAATTTTATCAGA
ATTATAGAAGTTTATATAAATACACAGACAGACAGAAAATTCAGCACTTGTAAGATTTTTTATTTGCCAGTTGTTAACTG
GACTACTGGCTTCAGAGTGGAGCCCTTGGAGGAACAGGGCCAGGAAAGCATGCATTTTTTTTCCAAGCTAAATAAGCAGG
CACAGCTGAAGGCAAAGACAGATCTCCAAAATGAAGGATGCCATTTTATACTGGATCCCAGATCCCCAAAAGGAAGGAAA
TACTACTGGAGAAGAGAGTGCAGTGCTTCTAACCTGCATTTTATTGCAAGGCAACCTAAAGCCAATCAACCCATTTTGAA
ATCAGCCCATCCCCCATGGAAGTCTCATCTCTCAGTCAGGCATGGGGATGTTTCCGTATCTTCCAGGTGGCCCAGAGCAT
GCTTCTCTGACCCAAGTGTGCGAAGAGCCAAGTTTCCCTCTGAAAATACTATTAGCCATCCCTTAAAGTATATTTCCTAC
CTAGTTATTACATACCAAAGCTATCTCATAATGCAAAGTAATTTCTGATATCCCCAAAATTCAAACTGTCAGATAACACA
ATGCAAAACAGAACAGAGCCTTTGATTTTGAGAGTGATCCATCTACTTTTAATTCCTTGGTTGTCATGAAGAAAACAGAG
GGTTTTTTGTTTGTTTCTTGTTGTTTGTTTTTCCCAAAATGGGGTCTGTGGTGCTTCCTCTGTTTTTCTCAAGGAGTCTC
AGGCTACCAAAAGTTATCTTAGTGCCTCTTATGTGTGCATTAAGAGTGGCAAGACAAAAAATGGAGAAAAATAATTCAGT
TTACTAAGAAGAAAAAACCCTCTTTTACAGAAAAACGAGATCCAAGAAGAGAAAAACATAAAGGTCTTTTAAATGTATCC
ATAACTTGTTTATTCACTTTTAATTAAGCTGACTTTTAACCTTAGTGCTCTTAACAAAATCCTTTTAAATTTCGTATTAC
CCAACTTTAGCCATGCGGCCAACATTTCTGGCTTTTGAACTTTATCAAAAGTAACTTCCCAGGTGCTTCAAAGGTGTGGT
AAGCAGTTTCTTTTTACAAGATTTAGAATTTCCCCAAGGTAGTCCAGAGAAAGGAAAATTCAAGAGAGGAAATCAGAAGC
TATCCATGGGGTTGTGGGGGAACCTCATTAAATGGCAAAGTTATGCAAATAGCAAACCAGAAGGAAATTGTTCCAGAAGC
CAAGAATAGAGCCTGAGCCTCTATGTCAAAAGGCAAAGTCTTAGCTACTGAATTACAGCATTGAGCAGTTTCTATTGCTA
TTCCAAGAAGGAGACTAGAGAAGCCACTTTTAACCTTGCCAAGGCTTTTAACTGCTCAAGAAAAATTTTTAGGGCTGGAT
GGTATAAACCAAAAGGAAGTATCCACATATGGTCACAAGATTAAGCTCTTAAGGAGGCCAAACAAGACAGAGAAATTTCA
TACAGTATTGGTTTCAGGGACCCATTATAATTGGCCAGCCTGCTGAGCTGGCTTGAAAAGCAGGCTTATAGGGGTCCTAA
ACCCATGTTCTATCTTGTGATACCCCTCTTTCCATTACAGAACACTGAAAGACAAATTCTTAGCAAAAATACACCAGATT
TGCTATAGGCTAAGACTAGTCTTGTAAATTCTTTTTTCTATTAATCAAAACTTTACAGAGAAACATATAGTGATGTTTAC
TGTTTACACAGATGGAGAAAGAGAGAGAGACCAGAAACCTAGCTGGTAAGAATTTCTTACACTTTTTGCTGGCATACCAG
ATTTCTGGGTGCCTTTTCTCTGTAACTTCCAGAAGAACGGAACGGCTTCTGATCAGCCTGCTCACCTCACCATAGTTGTG
GGGTTCAAGCCACTTTACAAGAAAAAAGTCACCATTTTCTGTTTTATGGAAACATAGGCAAGATTCTTAAAATGCAAGAT
GCTGCCCAACCAGCTGCATGGGGAACCATTTAACATTTTCTATCCCAGCAGAATTCACATAACAAAACAGACACTAGTCA
CCTCGTTCAGCACCCAATATCAACCTGGCAAAGCTCAGACTTTTTTCTGTTCGTCCCTGTTGTCTTTGATCCACTCCAGG
TGGGGAGGGACGACCTCAGAACAGTAATTCACAATGGGGTCTCTGGGTAAGGCAAAGAGCAGATAGTCACCATGAGACAG
GCCTATTGAACTTTCTCCAGGGCTCATCGAATGTAACCAAATAAGAAGAGTCCTCTGAGTTAGGCCTGCTGGACTTCCTT
CAGCAATTCCTTCTGAGATTCCCTCCACATATACAAACACACACGAAGATGAGACAGACAGAAGGCCTTCCAAATCAGAT
GATCCCTAAACAGGAACTCCAAGAGTATCCCTTCCAAACTATCCTCCTATTCTCTGTCTGAGAAATCTCAAAATTGTCCT
GATTGAGGACAAGTCTCGTGAACCAAGACTCTTCCTACTAGTTAGAGCCAACCAAGACCCCAGTGGAGCCGAACAGATAC
CCCGTGGTGGAGCTACAAACAGACACCCTGCAATGGGGCTACAGACACCCTGCAATGGGGCTACAGACACCCCATCATAG
AGCTACAGACAAGTCGAGAGAAGGAAGGAGGCATTAGCAGTGCCTAGTAGATTCACCAATCCTAACACCCTGCAATGGGG
CTACAGACAGACACCCCACTATGGGGCCACAGAACCAGTCAGGAGAAGGAAGGAGGCATTGGCAGCACCTAGGATACTCA
CCAATCCAGACACCCTTCAATGCAGCTACAGACGGAAACCCTGTGATAGGGCCACAGTTAGAGGACATCTCTCCAGGATT
ATTTCTCCGTTGCAATTAAATGCATGCACATTGGGTTGGCAGTGCCTGCCAGTGGAGAGAGTACCAGAGCCAGCCCCCAG
TCCAAGAGAACTAGGCGGCTACTTGGGCTACCTTCTGGATCCATCGCTGGAGCGGGGGCACCAAACCACAAGCAGGTAGC
CACAAAGGCTTTCCCAGTCTGATTTCGTTCATTGTTGTAATTTCCTCAGTTATAATTTTGCAAAGGTGGTTTCATATTCC
TTAAGAGTTGAGCCACACATAAGTTTTATTCATTTGTTCCTACATGGACTTGACTACTGATTCAGTAAATAATTAGTAAA
TATTCAGTAAATAACTAGTAAAAAGAATGCCAAAAATAGTGCAGATGTAGTTCATGGCCCCTGTCCTCACAGAGCATAAA
TTCTAACAGTGGATAGAGATAAGTAGGCTGGGAATCACAATTAAATGGAAAAATAAAAAAAAAGGCTGGATGTGGTGGCT
CAGGCCTGTAATCCAATAGCAGCAATTTGGGAGACCAAGATGGGTGGATCACCTGAGGTCAGGAGTTCGAGATCAGCCTG
GCCAACATGGTGAATCCCCATCTCTACTAAAAATACAAAAATTAGCCAGGCGTGGTTGTGTGCACCTGTAGTCCTAGCTA
CTCAGAAGGCTGAGGCAGGAGAATCGCTTGAATCCGGGAGGCAGAGATTGCAGTGAGCCAAGATAGCACCACTGCACTTC
AGCCTGGGTGACAGAGTGAGACTCTGTCTCACAAAAATATATAAATACATAAATAAATAAATGGAAAAAAAATGCTACTC
TAAGGAGATACAAGGTGCCCTAGGAGCATATATCTCTGATGCTGTCTCCTCTGGAAGAATCAGAGAGGATTCCCTTAAGA
AAATACCATCTAATCTGATACTTGAAGGATAGACAGATAGACAGATAGACAGAGAACAGTTCAAAAACCAGAAGAAATTA
GAAGCGGGGGTGCTGAAACTATACAGATCCCTAAGTAGAGACTTGATTCCCTGAGAAAGGTGCCATCTAATCTGAGACTT
GAAGGTTAGACAGACAGCAGTAGGAAAACAAGAATGAATGAGAAGGTAGGGGCTGGAAATACAGAGACCCCTAAATAGAA
TCTTTCCAGAAATTAAATGAAGGCAGAACGTTTTGAATGTAATGAGCAAGGTGGGAACAGTATCAGAAAATGAGTGAATG
AGAAGGCCTAGATTAGAATAGGCTGAAAGTTTTCATGGTCAAATCTAGATATTGGAACACTCTTCGTTGCAAAGAGTAGA
ATAGAGGGACGGAGAGTAGATTGATAAAGTTCTTATGAATTTATTTCTTAAGAAAGAAAGGATGTTGGCCCGAATAGAAG
TAATGAACAATTAGAATTGAGAGAAGTGGTCAGATTCTGAAAATGTTTAGCAAATAAAATCGATGCAATGTGAATTAAGA
AGGGAAATAAGACATAGAGAAGGCCAAAGAGGTTGAATATCACCAGGTATTGCTGCTCTTTTGTACTTGGAGTATAGGTA
TTATTTACTAGTATATGGAAAAGAGAATGAAGGATGGAAATGAAAAAATGAACAGTTCATCTTTGTAAGTTGAGTTAAAT
GAGGTTGTGAGATGTAGTTGAGATATCTCATTGTCTATTGAATGTATAGGTTTCAATACCGACATCCACATCTGGGCTGA
ATCCATAAATTTGAGAATGATTTATTTATTCTTTTAAGCATATAATGGATGCCATCAGAATGTGTAGATTATACCTCAGG
CCATACTTTTAATTTACTTATTTATTTATTTGACAAATAAACATTGTACATATTTTCTATGTACAACCTTCTGCTTTTAT
GAGTTTAACCTGTTTAGAGTCTATGTATAAGTGAGATAATGTGATATTTTGTGTTTTGGTGCCTGGCCTGGCTTATTTTA
CTTAATATAATGTTCTTCATGTTCATCAATATTGTCAGAAACGATAGGATTTACTTCCATTTAAAAGCTGAATAGTGTTG
CATTTTGTATATAATCCACATTTTCTTCATCTATTAATCTGTCCACAGACATTTAGGTTGATTTTATATCTTGGCTATTG
TGAATAATGCTGCAATGGAAATAGAAGTTCAGATATCTCCTCGAGACACTGATTTTCCAATTTTTGATATATACTTAATA
GTGGGATTGCTTGATCATATCTTTAGCTCTATTTTTAACTTTCAGAGGTGTCTCCATATAGGTTTCCATAAAGACCATGC
TAATTTACTCTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCACTCTGTTGCCTAGGCTGGAGGGCAGTCAT
GGAATCTAGGCTCACTGCAACCTCCGCCTCTAGGGTTCCAGCAATTCTACTGCCTCTGCCTCATGAGTAGCTAAGATTAC
AGGCGCCCACCACCACGCTCGGCTAATTTTTGTATTTTTACTAGAAGCAGGGTTTTACCATGTTGTCCAGCCTGGTCTAG
AACTACTGACCTCAGGTGATCTGCCCGCCTTAACCTCACAAAGTGCTGGGATTACAGTCGTGAGCCACTGCGCAGGGCCT
AATTTACGTTTTACCAACAGTGTACAAGAGTTTCTTTTTTTCTACATCCTCTCCACCATTTGTTATCTTTTGTCTTTTTG
GTAATAGCCATTCCAACAGGTGCAAAGTGATATTTCATTGTGACTTCAATTTCCCTGGTGGCTAGAGAGGTTGATCATTT
TTCATATACATATTCTCTGTATGTCTTCTTTTGAAAAGTGTTTATTCTGGTCCTTTGCTTATTTCTAAATCAGTTTATTT
TCTTTCTATTGAATTGTTTGTGTTCTTTGTATTTTGCATATTAATTCTTTATCAGATGTATGGTTTGCAAATCTTCTCTA
CCATACTGTTGATTATCTCTTTAATCTTTTGATTGTTTCTTTGACTGTGTAAAAGCTTTTTAGTTTGATGTAATTTCATT
TGCATATTTTAGCTTTTGTTTCCTGTCCTTTTCTGTCATATCCAAAAATCACTGTCTAGACCAATGTTATGAAGCTGTTC
CCCTCTGTTTTCTTCTAGTAGTTTCACAGTTTTGGTTCTTACATTTACATATTTAACTCATTTTGAGTTTATTTTTGTAT
ATGTTTAGAGATTTTTATTCTTCTGCATGTGGTTTTACAATTTTCCCAATATCATTTATTGAAGAATTTGTTCTTTCCCA
GTTGTGTGTTCATGAAACCTTTGTTGAAAAGTCAAATTAATGTAAATAATTGGGTTTATTTCTGGGTTTTCTGTCCTGTT
CATTTGCTCTCTGTTTCTATTTTTATGCAACTATTGTGCTATTTTGATGACTGTAGTACTTTGTAGTCTATTTTGAACTC
AGATAGTGCGATGCCTGCAGCTTTGTTCCCTTTACTCAAAATTGCTTTGCCTATTCAGGGTTTGTTTTTTTGTGTGTGAT
TCCATATAAATTTTAGGATTTGTTTCTATTTTTGTAAAAGCTGCCATTAGAATTTTGATAGGAATTGCATTGTATCTTTA
GATTTCTTTGGGTATTAGGGACATTTTAATAATAGTAATTTTCCAGTCCATCAACTCAAAATACATTTCTACTTATTTTT
GTCTTCTTCAGTTTTCCCTATCAATATTTTATAGTTTTGAGATTTGTTATTATTGCTGTTATTTTTGAGACAGGATCTCA
TTCTGTAGCCAAGACTGGAGTATAGTGTCACAATTATAGCTCACTATAATCTCAAATTCCTGGGCTTAAGCAATCCTCCT
ACCTCAGACTTCCAAGAAGCAAGGACTATAGACACATGCTACTATGGCCAGCCAACTTTTTAAATTTCTTGTAGAGACAT
AGTCTCACCATGTTGATCGGGTTGAAGTTTTATACTTTTACGTGTACTTGTTTTTTACCTACTCGGTTAAATTGATTTCT
AAGTATTTTTGCAGCAATTTTAAATGGAAATTTATTTATTTTTTAAAGATGGTTTATTGTTATACAGAAACACTACAGAT
TTTTGTATGTTGATTTTTTTTATCCTGCAATTTTCTTGAATCTGTTTATTTGTTCTAAAAGATTTTTGGTGGATCCTTTA
GGGTTTTCCGTATATAAGACCATTTCATCTTTAAACAGGCACAATTAAACTTCTTCCTTTCCAATTTTGATGCCTTTTAT
TTCTTTTTGTTGGCGAATTGCTCTGGTCAGAACTACGTTGAATGGAAGTGGTAAATGTGAATATCTTTGTCTTCTTCCTG
ATCTTAGAGAAAGGGTTTTCAACTTTTCACCATTGAGTATGATGTTAGCTGTGTGTTTGTCATATGTGACTTTTTTTGTT
AAAAACTCTTCAATTTTATTGCTTATTATATTTCTTCACATATCATTTATTCAGTCAACACTATATTAGTTTACTGAGCA
CACAAATAAATAAAACAGAAGCCCAGAACTCAGGTAGTTTGGATATCCCACACACTAATCTGTGTACTGTTTGCAAATCA
CACTGTGTTGCAACATCTGTACCTGATGTTGCAAGACTAACATTTTTGCTACCTCTTCTCAGAAGCCTTTGTGATCTCAC
CTGTTGGAATGCACTAATGTTTTCTGAGCCCCTTAAATATCTTGTCTACATTCTTTTAAGAAGCTCTTCACCAACTGTCA
GGTAATGTAGTTTGATGAATTAAGAATGGGGGCTCTGGATTCTGAACCCCTAGATTTCAATTCTTGTTCCCAGTTACTAT
ATACTCGGTGTTCTTTTACATTATTTGAGTCAATTACTTATTATCTTCCATTTTCCATATAAGAGAGGTTAATATATGTT
TTATATGGAATTTTTGTGAAATTTCAGTAATGCACTTGGCATGATGAGGGCTCAATGAATATTAACTATTTTAACTGAAC
CATATCATGATTAACTATATAGACTATGGTGAAAAAAACAAGATTTGAATCCTAATTCATGTGATGTGACATAAGTTATT
ATTTAAATGGTGAATATAAAATAGGGAATATAATAACTACCCCACTGGCTTATTGTGAGGGTCCAGTATATTAACATTTG
TAAAACCTTTGGTACAGTGATATGTAAATGATAATGATGATTATAATAATGATTTAAATTGTTTTATATGCATTCATTTT
TTATTTATAATAAGTACATGGGAGATATTACCCTTTACTAAGTTAATTTATATTATGTAACTTTTTTCCTGGTTTGTAAT
GTCTAATGTTTTTCTCATAATAGCTGCCCAATAAGCACGTATGAAAATATTAATTCAAGATAACCCAGACAATGAGGCTG
GTGCTTCTGTGCCAAAGCTTTTGTGCAATGTCCTGACATGATTTCTTTAGATGTCATTTTCTGTCAGCACTATCCTTACA
TCTACATGGATTGTATAATTATCTTTGTAGCATTGATTGAGAATTGATAAGATATCCAGCATTTCTGTGTACAATCTGCC
GAAATCATATCTGTTGTATTGAAACAAAGGATGTATTACTTTGGTATCTATATTTCCTTATAAATATTCAAATTACTCTA
AGGAGTAATACATTAACATGGTGTCAAATTAAACTAATCCACCACACTGGAAGATTAGGAATCAGGTTACTTTCAATTTT
AAATTTTCATTGAGAACAAGATTTGAAAGAATTATAAATATGGATGCACTCATCCATTTATTCTTTAATTTATGTATTTA
GCAAGCATATTAAGTACTTTTAAACATTTTGAATACAAAGATGTGGGTATAGGATGTAAGTTAAAAAAATGCAAATTCAA
AGATATAGTTCTTTCACCAAGAAAACTAAATACAGAAAAGAGTAAAAATCATATAGGAAGTAAAAATCTAGTAGGAAGAA
TTTATATTCTAGACAAGAGCATTGACTTTCCCGGGAATATATATTTTAGGCAGATCATTATCACTATGGGCCGTGAACCA
GTAAAAGAGAAAAATGAATACAGTGGATGACCAGGAAGTTTGCATTAGGTCCAATGCCACAGAAGGAAGTTGAGAAGCTA
AAAGAAAAGAAAAGAAAAAAGAACAAAAAAGAAAATAAAAAGTATTTAGTGGCAATAAATTGTTAAACAACCTGGTAGGA
ATATGATGAATGACAGAACTCTATAGGTACAAGAAGACAGATGGTGAAGTAGGACATACTTTCAGAAGTATTTCACATTA
TAGAACTATATCTAAAGTGAGGGTGAAACTCTTTAAGCTGTGCCCATAGTTAAAGGAATCTTTCTATTTCTAACAGAAGG
CAACCACAGAAAAAAGCCACTTAAGGTGTTGGAATCCCTGGGCAAAGATTTCCTCACTGGTGTTTTGGATAACTTGGTGG
AACAAAATGTACTGAACTGGAAGGAAGAGGAAAAAAAGAAATATTACGATGCTAAAACTGAAGACAAAGTTCGGGTCATG
GCAGACTCTATGCAAGAGAAGCAACGTATGGCAGGACAAATGCTTCTTCAAACCTTTTTTAACATAGACCAAATATCCCC
CAATAAAAAAGGTAAGACTGGATTTTTTACAATGAATGTCTCAATTTTCCCTAAATCTGTTTAACTCCAAGGCCTAAGCA
GTGTCTTCTGTGATTCCCCTATCTTTCCCTTCCTAAACTATCATTTTCACTAAACCTATCTTTGTCCTTTTAGAGACCAC
TTCCCTTTTGTGGGGTGGAATCCAGTTTACAATCAGCTAAAAGGCTGAGTCCTTGTGTTCAGACTGTGTACAAAAATAGT
TAATAGTTCACACCTTGTAGTAAGGGACACATAGAACTAAACCTAGATTCTGTCACCTGTGACCTATGTGACATCCTGTA
AGTTGCTTAACTTCCCTAGATCCTTAGTTATTAGTCTTACCATCTGTGAAATGAAGACAATTCCAGTACTTTCTCACAAG
ATCGTCTAAGCCTAGAAACATTATAATGACAGGCACCACACGCCAACAACTCTCAAGATATTAGCTCTCATCCGGAACTC
TCTCCTCTGAACTCCAGGATCATTTAGCTCTAGCAACATATTCAACAGGTCTACTTGAGTGTTTTGCTGGCATCACAATA
CAAATACAGCTAAAATATACACTTTGTTCCCCAGAACAAAACTGTTGCATTTTTATTCCCTTTTCATCTCAGTAGACCGA
AACAACATCTACCAAGTTTCTCCCACCAGAATGCAACTGGTTTCTTCACCAATTAATAACAGTAATCAGTAGTTTTCTTG
GCACATAGCAGATGCCTAAATAATGTAGGATGAGTAAATAAATAAAGTATATGCATTCAATAAATACTAGTTTTCATAAT
TATTATGTGGATGCTATGAACTAGACTTTTCCAGTGCTTACTTACTTCTGCGAATTACAAAATATGATAAGGAGAATCTC
CATAAAATGTCTAAAATTTTAAAACTTCTTTTTGGAACTTTTGACCCAGATTGAATTACGTATTATTAAAGGTTAAATAT
TCTCATATTGAAGTTCACCAGAGACAGACTCAATACCCCCCAGAATTTAAGCTGAAATCTTGAGCCATGAAGTATTACAG
ATTACCAATAATGATAAATAGTGATAAACAAAAGGAAATATAAATTGTTGAGACCTCACTATATCAAATGAGCTTTTTCA
ATCAGCACTCCTCTATGAAGAAGGGGTGTTCCTACCAACAGGGAGCACATGATAGTATGATAGTTGTCCAAGATTATAAG
AAGGTAGCATTCTCATTAATATTTAAACTGGTCCCTTTGCAGGTTTTTAGTTTTTTCTCAAACCTGGATGGCATGGAAAC
AATCTCCATTTTCAAAAAGTCAGTGATAGTGCAACTAATGGGAATTAGAATAGAAGTAATAGAGGCTTCAGAATGGTTTT
AGCAAACCCAGATATCACAATGAGCATTCAAGTCTAAACTGAAGTAATCTATCTGATTAGCAGAGGCTGTGGCAGGAATA
AGGCAGCGGCAACCCCTCACAGGAGGGGTCTAGTGTCTCCCTGGGCTCTATCTGCAGTTGGAGTCTCCAGAGCAATCCCA
GGAAACTTTAGGTACACTGCCAGTGTACCTAGAGTGTATCCAGCTCTCTTTGGGCAGCAGTCTGCAGTATAATATGTACT
ATCTTCTAATGAAATGATTTGCTTTCATGCTAATTTTATTATTGGATGTAAGATAGAAATTCTATCTAATTTCTAATTTT
ACCTGAAAACACTGTATCTCACACACACACATAATGATCATTAGGAGATGACTAAGTTATGAAGTTCTCTAAACCTGTAA
GTGAAGTGGAAACAGGAAACTTTGGATTAGAAAACATACCCTCTGACCAGGGAATATCCAGGATCCAGCATGTCTTCACA
TTGGCAGAATTTTCTGAAATAGGACCGAAGGTCATATATCACTGTGTAATCTATGAAAAGAGATGCTCAGAAGGTTTGAT
ATTCATACACACTCTTACAACTTGTTACATCTCCAGAGCTCAGACTGGCTGGCTTTACAAATAGCTGGCTTTACAATTTG
CACAGGGATAATTGAAGTTCATTTCTTCTAGAATCATTAAAAATTAACAGTAAAGTTGCTAAAAAAATAATGCCTTGAAA
GTACAAGATTCAATATTCTGTGCTTTGGTGTATGTATGTATTTATCTGTATGTGTAGTGGGGATTAGGAGGGGACGATTA
CTCCAAAATAGGATTTTGTTCCATCCTGTATGGGATAACTATTAAGCATTTGGCTTGTGGCTAAAAATACATGTTAAAAT
AATACTTTTTGTATGTTATGTTAAATAAATGTTATTAGAATTAATTTTACCTGTTTAATTTTACTTTTTACATGTGATAG
TAGAAATTAAATATTGGACATGGAACACACATTAAATTTGTAGTAGATAGTGTTCTGACAACTATTTACTCAGTATACTC
TTGCACAGACACAATAGAAAGTCCACACAGATAAATGAGTATCCTGGAGTAAAACCTTTGGAAAAATCAAATTCTTTTGA
CGGTATAAGGAAAGGCCAAATTTAACCCCAACATCATTGACATGTTTTCCCCAGAATGATCAGAATATATGATTACATGT
TTGGGTGGATCTGCTTTTCTATCTTTTCCAGTAACAATACATCTCCTGATGTAGAATACTAGATATGAGATACAACTAAA
ACCCCTATATGTGAAGAAATCTTCCCAGGACGTCTTCTCTCTCGATCTTCTTAGGTGATAAATTGGGTCACAGAGGCAGA
AATCACAATTTATGTTCTGCAATATCCTGCAGCTCATCCGAATATGGAGGCTGGACCACCTGAGTCAGGAGAATCTACAG
ATGCCCTCAAGCTTTGTCCTCATGAAGAATTCCTGAGACTATGTAAAGAAAGAGCTGAAGAGGTGCTATGCTATCTATAT
GAAATAGAAAAAAAAGAAGAGATATCATTGCTTTCCTTCAGTGCACCATTTCTTACAGCACTAAATGATTGGGGGTGGGG
ATGACAGTAACCATTTTCAATAATGCTTTTACTAAGGGAAAGATTATGTGACTTCACAATGATACCAATCCTTTCTCAAT
CCATGATGCAGATCATTTTATCATGAGTTGAAAGAAAATTGGTATTTCTATTGCTCCTGTATTTATTCTTGTAATTATTT
GGATTTTATGGCAATTGTAGCATTAGCCATGGAATAAACATATTTGGAGGATAATATAGCTGACTTGTAATTGGTTGCAC
TCTACTTGAAAAGTCTAGACATGAAGGATACTTGGGAAATATAATTAAAGCTTGAAAAACATTATAAATTTATGTGTTAA
AAATAGTAACAAAATAGCTATGCTTCCGAAGGCAAAGACTTTTGCTGTATTCATTTTTCACTGGAGTCAACGACAACATC
TCGTTTTGTATGAAATTTGACCTGAACTTTGAATGCTAAGAAAGATTGGAGTAGGTGAAGAAGAAAAGGGAGAAGAAAAG
GCATAGGAATTATCTAGTTTCCTCAAGATTCTTAATAACAATTTCAGATATGTCCGGTTCTTTCCCTGGGTTCTTGAGAG
AGAGAAAGTCAGTGTCTTTTGATACAAGTTAGAGCAGAGAGGAGCTGCATGAAGACTTGAAAAAGCAACACTGATAGGCA
TAAGGAGGCTGAAAGGAGACTTGAGTAAATTAAATTTATTGCATCTCCATATCCTGCAGATCTATCCAATAAAGGAGAGA
AACAACCGCACACGCCTGGCTCTCATCATATGCAATACAGAGTTTGACCATCTGCCTCCGAGGAATGGAGCTGACTTTGA
CATCACAGGGATGAAGGAGCTACTTGAGGGTCTGGACTATAGTGTAGATGTAGAAGAGAATCTGACAGCCAGGGTAAGAA
TCCCTCAGCCGCCACAAACACATACATATTCAAGACACATCCTTCTAATAACTACCTAGCTTCAAAGAGCTCAACAAGGT
TTAACAACCTTTGGGTGTGTGTGTGTGTGTGTGTGTGTGTATACAAAATAAGAGTACTAGACTGGTAAATCTATGTCTCT
TTGGTCCTCCAAATATCCTCAATTCTGGAAAACTAGACTAAACATGATTGACACGTGTTTTCACATTTCTTATTGAATTC
CAAAATCATGTGATTGGGATGCAGCCCCGAAAATCCCCAGAAAATTGTAGAGTAATGAATGTTAAATGGCAGTATACTTA
TAAAACAAATATTGAATCCTAAACTTGGTGCTAAGAGCTATTCCTAACGTTGGGAATAGGTCTGTAAATGAGACAGGAAG
TTCCCAGCCAGCATTCATCTAGGTTACAGTAGAGAGAAACAGTGAAATTGTAAGAAAAAAGACAACTTCAAGCACCAGGT
GTGCATATGTGTGTCTACAAAACAGCGACAAGACAGCCAAAAGTAAGTAAAAAGAAAATAAAAAGGAAATATGAGACAGA
ATTGTAGGGTGGGGAGCAACGTTTTTGGGTTGGTTGGAGATGGCTCTGGAAAGACATGAATGCAGCGCCTTCAAAGTAGG
AGACGCCACCTGTGAAAGAGCTGAGCTGAAAATGAACCTGGCACACGAGAAGCACAAAGAGAAGACCAGTGTGACTAGAG
GTTGAAGGAGAAGGAACATAGTATGAGGGTGGTGTATGGTCAGGCCAGAAGTTTGATTCTATTCTAAGCATAGTGGGATG
GATTTTACAAAGAACATGGTGTGTTGCATTTATAACACATGACTTGCTAGGTAAGGAGATAGAAGATTGAGATGGAAAAG
AAAAAGTAACATGAGTAACACATAGCAATATACAATATACTAAGAAGACAGTATGTCAGCAGGAAGAGAAAATGGGAATC
CACGGCCCCATAAAGAAGGAAAAATAAAACCATTAAACAGCTGTCATGACTGAGTAAGCACTAAGTGAAGCACCACGACC
TGGATGTTACATATGTTTCTTGTTTCGCTCATGGTAAATCTAGGAGTCCCCTTTAATTGTGATGCTTCTCTGACTGAAGT
TAGACATTGCTCTTTTACAGGATATGGAGTCAGCGCTGAGGGCATTTGCTACCAGACCAGAGCACAAGTCCTCTGACAGC
ACATTCTTGGTACTCATGTCTCATGGCATCCTGGAGGGAATCTGCGGAACTGTGCATGATGAGAAAAAACCAGATGTGCT
GCTTTATGACACCATCTTCCAGATATTCAACAACCGCAACTGCCTCAGTCTGAAGGACAAACCCAAGGTCATCATTGTCC
AGGCCTGCAGAGGTGGTGAGTGCTGAGACTGAACATCTAACAGTTATGAAGGTGTATGCAGAGGATTGTGATGTTTGGTT
TATATTTAGGGGCAACATTCTTAAACCTCATCCAGTGTAAATAAAGTACATTGAATTCTAAAGAAACTCTACCTAAGGGT
CTGGTATAACAAGAAATTGTCTCATCAAAATTAGTGGAGAAATTTCTGTTCAATTTTATCCACAGTAAGTGGTGAAGGAG
ATCATCAGAATCCCTAAATCAAAGTTAAACAGAAATACTCAAACTTTGGAATGGAATCATTTTCATGATAGCTTGATTTG
TAAATGTTTTACAGAAATTTTGACATTGTGTGGTTTGAGAAGAATTTCATTTGAAACTGGGGCCATTATGTAAAACAGCA
TCCCTTTTTCTTATAATTATTGAGGGGGAAATTAGTAAAGAGATCAGGGGACTGTAGAATGTTGCAGTGCCACTTTGCTC
CAAAGATTCAATTGCCTCATGGCTGGCTGAGGATGGTGGCTCATGCCTATAATCCCAACACTTTGGGAGGCCAAGACAGG
AGGATGGCTTGAGGCCAGGAATTTGAGACCAATTGTCTGATAGCTCTTGGGAGCTATTTTTCAAAAGAAAACAGATTTTT
TTTCTAGAAAATGGTAAATTCAAGATGATTTCACTATCAGTAGGCACATTGTTGAATGACACTGGAGAGAAAGAAAAGTG
GTGTGTGTGTGTGTGTGTCTCTCTCTGTGTGTGTTTGTATGTGTGTGGGTCTGTATGTATGAAACTAGTAAGAATGAACA
TTCAAAAAGAACAAGGTGGGCAACTGTGACAGCCATTCTGTGGGAGGCACAGCAGTGTGCAGAAAGTTAATGTCTCCATA
GCAAACCGTGGGGAACTGTGGGTCAGAGACTCTCCAGCATCCTTGGAAGTGGCCTCTTCACAGTCATCTGAGAACCTAGA
GGAAGATGCTGTTTACAAGACCCACGTGGAGAAGGACTTCATTGCTTTCTGCTCTTCAACGCCACGTATGTATCTTTCAG
TGGCAGTAAGGGATTTGTGGGCCTGAGGCCATCTTTGAATGAATCTAGAAAATCAAGAATCCCTATGAAACAATGATCTG
ATAGAATGTTGTGTGCTCTCCACATATTTTACATGATCTTATGTGTGCCGTGAGAACAGATTCCTAAAGCAACCCGATAC
ATGGAAACCCATTCACCACTCACCATTTAAACAGATGATGAATTCTGTTTTTTTTATTAAGCCCATTTAACATTTTACAT
AGTGTTTTTATGGATTCCAGGAATGGCTTCTCTTTCTCAAATGATCAACTTCAAGTCTTCTTTCCATATTTCACATCTGA
TTCTACAATGAGCAGTGCCATTGCATGCCCTGCTAGAACTGTGGATACCCTTTAAAACAAGTAGAAAATGATAGGGTGGG
GCTGATTAGGTCTAATCTCAGGGAACACTGGTTAGTATTTCATGTCTAGGTAATTATCTTAAGGAGCGTACATTTAACTG
TTTTTGATTTGTATATTTTTAAATCTTATTTTTTAAAACCACTTTATTGAGGTATGATTGACATACATAATGTTACATAT
TTAATGTATACAACTTAATGAGTTTGGAGATTTCTATGTACTCCTGAAATCATCACCACTATCTATGCCATAAACATATC
TCTCTTCTCCAAAAGATTCTTACACTTCTCTGTTTATTATTATCATCATTCCGTGACTGCGTGTGAGAAGTATACTTAGC
ATAAAATCTACTCTCTTAACAAATTTCAAGTACATAACACAATGTTGGTTACTACTGGCACCACCCTGTACAATAGATTT
TTATCACTTTTTTCAGCTTCTATCACTGAAACTTGTCATGTGTTCATCTATTTCTATTATACGGTGAAAGACAGTGTGGC
ATAATCTGCAAACAACTTTGGAGCCTGGTGGCAATTTTTTGTTGCTTACTCACTGTGTGAACATGGGGAAGTTCCTTCAT
CTTTCTGTGCTTCTATTTCTTCCTCTGTAAAGTGGGATAATTCTAGTTATTTCTCAAGCCCCTATAAAAGCTGAGAGAAT
GAACATGAGTTTTGTAGTAGAAAGCCAATCCCAAGAATCAAAATTTCTTCAATACACAATCTCTTGCAATGCTTACCAAC
TGCAACTTTTGATCACCTTTTGCTAGGTTTTCTGTTTACGTTCTGTGGAAAGTAGGTAAATGTCAGGTTGTAAGTGCTTC
CTACAAATCTGTAAAGATAATTCCCAAGCTATGCTTTTCTTTTTAAAAACATTCTCAAAACAAAAATATGAACAAAAACA
TAGTGAAAGTCATAGCCCAAGGCATACCCATCTGTATCATTATAGACAACGTGTCCTGGAGAGACAGCACAATGGGCTCT
ATCTTCATCACACAACTCATCACATGCTTCCAGAAATATTCTTGGTGCTGCCACCTAGAGGAAGTATTTCGGAAGGTAAG
TGTCTCTTTTCTAGTTACTCATTTATTTCTTCAGGAAGAATTTGTCATGATTCACTTTTTACTTCACAATGACAATTTTT
GTCAGGGAAGTGAAAGTAGAGAGGTACCCAGTTTCTGTCATTCAGTTGTTTAAAATATGGCTAAGGAAAAGACAATTCCA
ATATATCCCAGCAGAAGATCAAAGTAAAATAAAATAATATCAACCATAAGCTTTATGTTATGGAGCGTAAGTTCTTAAGT
TTTAGAGAAGGAAAAATATTTTGAAATAATTTTTATTTCTTAATTTATTAAATGAATAAAATCTGGGTGGTCTGCTAGGT
CATGGATTTCCTCCTGGTGACAGAGGGGTAAATGAGGCCTACATGACGTAATCCTATCTAGGACTCACATTTTCGTGGGA
GATATGGATACTGAAAATGTGGGTTAACAAACAAATATGTGCTTACAGATTGTGATAGGATCCATAAAGACATGTGAGAG
GGAACAAAAAAGAAGTCATTCTTTCAATAAAAAAGTGCAGAAGGAAAGGTTTGCTACTTCTTGCCCAACTTGGGACATTC
CTTATTCCCACTACTTCCTATGTTATTTTTCTCCATAGCTCGTACATCTACCCACTCAGCAAATATTAATAGTTTATTTA
TGTGTCTGGTTTTTTACTTGTATTTACTCACTAACATGCAAACTTCGTGATGGCAGGGATTTGCTCAGCAATTCAACAAA
CCTGGCACGTAGCAGATATTCAATTAATAATTATTGAATAAATACATGCATAAATACACAGATAAATGCACCCTCTTGTT
TAAAGAGAAAATGGGATTGGTATTAACACAGAATAGTATAATTATTAATAAAGTAAAAATTGTAGAGAACAGTAAAACTC
CTGCGGGAAAAGAAAGATACACCTCTGGCGTTTATAGAAGAAAGCCATCCAGAACCAGCACAGTCACTCATTCCTGTAAT
CCCAGCACTCTGGGAGTCCGAAGGAGGGTGGAGTGGCTTGAACCCAGGAATTTGAGGCCAACCTGGGCAACATGGCAAAA
CCCATCTCTACAAAAAATACAAAAATTAGCCGGGCATATTGACTGGAACCTGTAATCCGAGCTACCTGAGAGCTGAGATG
GGAGAATCGCTTGAGCTCAGGAAGCGGAGGTTGCAATGAGCTGAGATTTCACCACTACCCTCTAGCCTGGATGACAGAGT
AAGACCCTGTCTTAAAAAAAGAAAAAGAAAGAAAAGTAGTGAAATAAGAAGAAGGAGGAGGAGAAGGAGGAGGAAATGCA
GCATAAATTGAGACAGAGCTCCTGTGAATAGAGATCTGGGAAGTTAAATCTTTTAAATCTTCTTGGATAAGTGGGAGTTA
GACATTGTACTTTCAAGGATGTTCATAGAAAAAGGAACTAAAAATTCTGGATTTAGGATAAGTAGACTTACCAATTAGTT
GATGCAAAAAAACTACAAGATCAGCTTGGTGGTGGAGATATGAAAGTTGTTCAGTGTTTGGGTCTTAAAGATAAGATACT
GGGGCTGGGCACGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCAGAGGCAGGAGGATCATGAGGTCAGGAGTTT
GAGACCAGCCTGGACAACATAGTGAAACCACGTCTCTACTAAAAATACAAAAAACCAATTAGCTAGGCGTGGTGGTGGGC
ACCTGTAACCTCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAACTCTGGAGGCGGAGGTTGCAGTGAGCCGAGG
TTGCACCATTGCACTCCAGCCTAGGCAACAGTGCAAGACTCCATCTTAAAAAAAAAAAAAAAAAAGAAAGATAAGATACT
GGGATTAAATTCTCCTTCAATTGAGGAATCAGCCTTGGTGAGTGTTGAAAGTACAGAGTCCTTCCTTATCTGGTTTTCAT
GAATAGTTTTCAAGGGATAACTTATTGTCAGATCTGTAGGTCAGAAATGGAAAATAGAGGAAATGAATGTTGAAAGACCT
TGGATTAGACATGAGGTGTTTATTTTGATGTAAAGCATACAGTCTGACATGGAGTGGCAATTCTAAGAGGTAGGGTACAA
TGTTGAGGAGTTAGAATGCCCATGGGCTTGGTTCTATGAAACCTGCAAGCTCACTTCATTCCAGGTGTTGTCTGGTACAT
GGTGAAAGATGCTTTCTGAGACTTGAAAAGAGTCGTATCTCATCTACAGCCTATTTTCTTTTTCAGGTACAGCAATCATT
TGAAACTCCAAGGGCCAAAGCTCAAATGCCCACCATAGAACGACTGTCCATGACAAGATATTTCTACCTCTTTCCTGGCA
ATTGAAAATGGTTAAGTATTGAGAGTTGTTGGTGGTATGTGAAATAAATAAGAGAGTGATATTGGTGGTTAAGTTCAATG
ACAAATGACAGCTGAGTACTTGGATGGTCAAATTGGTGTTTTTGTTGATATAGTCTGGTGATTATCTGCTACTTCTTTCC
GACTTACATGTATTTGGATTCCTCCAACTCTACAATTAATCAGGCAATCAATCAATCAATCAAGGAGGTAAGGAAAACCG
CAGCAGAATGTGATGATGAAAAACCAAGGATAGTAATTATTAAAATAGAAACATGCTCATGCTTCCATTACTATTTATAT
TCATTTATCTCTCATAGTCTTTCTCTTTTATTCCCCTTTCTTACACACACACACACACACACACACACAGAGAGAGAGAG
AGAGAGAGAGAGACACTAAGTAGCCAAACATTGCATCAAACCCTAAACAAAACAGAGTAAACAAAGGAGCTAACTCTGGA
GAAAGCAGCATTTTGATCCTCTGAGTGAGGATGTCACAGCAAATACCACATTACTGACATCCAGATACCATTACCAGATG
GTACAGAATACATCCTACACTGTAGAGTTTGTGTTGATCCAGGCTCTGGTTCTCAGACTGTTCTCACAATGCAGATCACC
AATCACTCAGGGTTGGCTTTTGAATCTTCAATCACAGTCCAGAAGTTCCTTCAAGCTCCCATGTAACTTTTGTTATTATT
TTGACCAAAATATTATAGAATGGGTACATTGAGTCTGGACTAAATGATGACTTTCTTCACTCATAATAGCTTTATTTAAC
ACTAGACTATAAGACTATTATCAATCTCCCTCTAAGATACATACTTAAAATTATATTTTATAGTGAAATGTATAAAGTTG
TTCTCAATACTTCCAACATTTACCACATAATTTTTACTCTTGGTTTCTGACACTTCAGTCACAATATTGCATCATTTCAG
CATAACAGCTTTCAGTGCCTAATCCATCCAGTGGGGCTGCATTTGGACATTGAATTGTTTGTTGACTAATATTTGCCAAC
ACTAACTGTGCACCAGGTTTTGTTCTAGATGCTTGGAATATGCCAATTAACAACGTAAATAGATTTCTTACACTCTGAAA
GCTTATATTCTAGTGAGTAGAAACAGACTCTGAAGACATAAAGTGGTAAATATATCACAGGCCGGAGAGCAAAAAAAGAT
AAAAGGAAAAATAAAGGAAGACAAAGGAAAACACAGAATGATGGATGCTGTACTCCTATAGATATTTCACTCAAAAGCTT
TTCTTGAAATAATGAAATCAGAACAAAGAATGGACAGAGTTGGGGAGTGAATAATGTGGTTCTTATGCAGGAAAAGTGTT
CCAGCACAGAATACAGCCAGTGCAAATGCCCTGGGATAGCAATGCACTAAACATGTTTAAAGAACTGCAATGAGACAGTG
TGACCAAAAGAGAACGTGAGTGGAGAAAATGGCAGAGACAAATTAGGAGAAGCAGTGAGAAGCCAGATCGCGTGGTTCTA
TGTTATCACATGGTAAACCTTTAAAAATTATTATCTGAGCGAGACAGGAAGCCTTTCTAGTGCTTTAGAAAAAAGAAGTA
ATATGCTTTAAATTAGGTTTTACAAAGATCACATTTTGGTGAATAGACTAAGATGTCACAGATGGAAGTCAAGGGAAGTG
GCAAGAGCACATGGAAGAGGATGCAAGAAGAATCATGATGAGGGATGGGATGAAGGCAGCAAGGGGTAACCATCTTGACC
TTCTGTTTTTTCTCTCCCCTGCAGGAAGCCACAAGCAGCCCAGCCCTCCTTAATCAACTTCAAGGAGCACCTTCATTAGT
ACAGCTTGCATATTTAACATTTTGTATTTCAATAAAAGTGAAGACAAACGAA
|
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|
Primary source |
RefSeq : NM_001225.3 (GI:73622123)
|
Name |
Caspase 4, apoptosis-related cysteine peptidase (CASP4), transcript variant alpha
|
Type of transcript |
mRNA
|
Organism |
Homo sapiens
|
Length |
1319 nt
|
Map |
11q22.2-q22.3
|
Location |
Chromosome 11 (NC_000011.9) strand : -
104813593...104813699 | 104815474...104815577 | 104817809...104817918 | 104819259...104819402 |
104820269...104820503 | 104821651...104821824 | 104822622...104822731 | 104825473...104825727 |
104839245...104839324 |
|
|
|
|
|
|
|
|
|
|
|
|
|
Exon(s) |
Start |
End |
Length |
is coding |
Exon 1a
|
1
|
80
|
80
|
1
|
Exon 3
|
81
|
335
|
255
|
1
|
Exon 4
|
336
|
445
|
110
|
1
|
Exon 5
|
446
|
619
|
174
|
1
|
Exon 6
|
620
|
854
|
235
|
1
|
Exon 7
|
855
|
998
|
144
|
1
|
Exon 8
|
999
|
1108
|
110
|
1
|
Exon 9
|
1109
|
1212
|
104
|
1
|
Exon 10
|
1213
|
1319
|
107
|
1
|
|
|
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|
ID |
Class |
Location |
Mutation |
Length |
is synonymous |
Source |
rs72978981
|
SNP
|
26
|
c/g
|
1
|
?
|
dbSNP
|
|
|
|
|
|
|
|
|
|
|
|
|
Primary source |
NCBI : CCDS8327
|
Nucleotide |
CASP4, mRNA isoform alpha[NM_001225.3] : 74...1207
|
Length |
1134
|
Location |
Chromosome 11 (NC_000011.9) strand : -
104815479...104815577 | 104817809...104817918 | 104819259...104819402 | 104820269...104820503 |
104821651...104821824 | 104822622...104822731 | 104825473...104825727 | 104839245...104839251 |
|
Start codon |
1
|
Translation |
NP_001216.1 |
|
|
|
|
|
|
|
|
|
|
|
|
1 |
ATACATAGTT |
TACTTTCATT |
TTTGACTCTG |
AGGCTCTTTC |
CAACGCTGTA |
AAAAAGGACA |
GAGGCTGTTC |
CCTATGGCAG |
|
81 |
AAGGCAACCA |
CAGAAAAAAG |
CCACTTAAGG |
TGTTGGAATC |
CCTGGGCAAA |
GATTTCCTCA |
CTGGTGTTTT |
GGATAACTTG |
|
161 |
GTGGAACAAA |
ATGTACTGAA |
CTGGAAGGAA |
GAGGAAAAAA |
AGAAATATTA |
CGATGCTAAA |
ACTGAAGACA |
AAGTTCGGGT |
|
241 |
CATGGCAGAC |
TCTATGCAAG |
AGAAGCAACG |
TATGGCAGGA |
CAAATGCTTC |
TTCAAACCTT |
TTTTAACATA |
GACCAAATAT |
|
321 |
CCCCCAATAA |
AAAAGCTCAT |
CCGAATATGG |
AGGCTGGACC |
ACCTGAGTCA |
GGAGAATCTA |
CAGATGCCCT |
CAAGCTTTGT |
|
401 |
CCTCATGAAG |
AATTCCTGAG |
ACTATGTAAA |
GAAAGAGCTG |
AAGAGATCTA |
TCCAATAAAG |
GAGAGAAACA |
ACCGCACACG |
|
481 |
CCTGGCTCTC |
ATCATATGCA |
ATACAGAGTT |
TGACCATCTG |
CCTCCGAGGA |
ATGGAGCTGA |
CTTTGACATC |
ACAGGGATGA |
|
561 |
AGGAGCTACT |
TGAGGGTCTG |
GACTATAGTG |
TAGATGTAGA |
AGAGAATCTG |
ACAGCCAGGG |
ATATGGAGTC |
AGCGCTGAGG |
|
641 |
GCATTTGCTA |
CCAGACCAGA |
GCACAAGTCC |
TCTGACAGCA |
CATTCTTGGT |
ACTCATGTCT |
CATGGCATCC |
TGGAGGGAAT |
|
721 |
CTGCGGAACT |
GTGCATGATG |
AGAAAAAACC |
AGATGTGCTG |
CTTTATGACA |
CCATCTTCCA |
GATATTCAAC |
AACCGCAACT |
|
801 |
GCCTCAGTCT |
GAAGGACAAA |
CCCAAGGTCA |
TCATTGTCCA |
GGCCTGCAGA |
GGTGCAAACC |
GTGGGGAACT |
GTGGGTCAGA |
|
881 |
GACTCTCCAG |
CATCCTTGGA |
AGTGGCCTCT |
TCACAGTCAT |
CTGAGAACCT |
AGAGGAAGAT |
GCTGTTTACA |
AGACCCACGT |
|
961 |
GGAGAAGGAC |
TTCATTGCTT |
TCTGCTCTTC |
AACGCCACAC |
AACGTGTCCT |
GGAGAGACAG |
CACAATGGGC |
TCTATCTTCA |
|
1041 |
TCACACAACT |
CATCACATGC |
TTCCAGAAAT |
ATTCTTGGTG |
CTGCCACCTA |
GAGGAAGTAT |
TTCGGAAGGT |
ACAGCAATCA |
|
1121 |
TTTGAAACTC |
CAAGGGCCAA |
AGCTCAAATG |
CCCACCATAG |
AACGACTGTC |
CATGACAAGA |
TATTTCTACC |
TCTTTCCTGG |
|
1201 |
CAATTGAAAA |
TGGAAGCCAC |
AAGCAGCCCA |
GCCCTCCTTA |
ATCAACTTCA |
AGGAGCACCT |
TCATTAGTAC |
AGCTTGCATA |
|
1281 |
TTTAACATTT |
TGTATTTCAA |
TAAAAGTGAA |
GACAAACGA |
|
|
|
|
|
|
|
|
|
|
|
|
>gi|73622123|ref|NM_001225.3|Caspase 4, apoptosis-related cysteine peptidase (CASP4), transcript variant alpha
ATACATAGTTTACTTTCATTTTTGACTCTGAGGCTCTTTCCAACGCTGTAAAAAAGGACAGAGGCTGTTCCCTATGGCAG
AAGGCAACCACAGAAAAAAGCCACTTAAGGTGTTGGAATCCCTGGGCAAAGATTTCCTCACTGGTGTTTTGGATAACTTG
GTGGAACAAAATGTACTGAACTGGAAGGAAGAGGAAAAAAAGAAATATTACGATGCTAAAACTGAAGACAAAGTTCGGGT
CATGGCAGACTCTATGCAAGAGAAGCAACGTATGGCAGGACAAATGCTTCTTCAAACCTTTTTTAACATAGACCAAATAT
CCCCCAATAAAAAAGCTCATCCGAATATGGAGGCTGGACCACCTGAGTCAGGAGAATCTACAGATGCCCTCAAGCTTTGT
CCTCATGAAGAATTCCTGAGACTATGTAAAGAAAGAGCTGAAGAGATCTATCCAATAAAGGAGAGAAACAACCGCACACG
CCTGGCTCTCATCATATGCAATACAGAGTTTGACCATCTGCCTCCGAGGAATGGAGCTGACTTTGACATCACAGGGATGA
AGGAGCTACTTGAGGGTCTGGACTATAGTGTAGATGTAGAAGAGAATCTGACAGCCAGGGATATGGAGTCAGCGCTGAGG
GCATTTGCTACCAGACCAGAGCACAAGTCCTCTGACAGCACATTCTTGGTACTCATGTCTCATGGCATCCTGGAGGGAAT
CTGCGGAACTGTGCATGATGAGAAAAAACCAGATGTGCTGCTTTATGACACCATCTTCCAGATATTCAACAACCGCAACT
GCCTCAGTCTGAAGGACAAACCCAAGGTCATCATTGTCCAGGCCTGCAGAGGTGCAAACCGTGGGGAACTGTGGGTCAGA
GACTCTCCAGCATCCTTGGAAGTGGCCTCTTCACAGTCATCTGAGAACCTAGAGGAAGATGCTGTTTACAAGACCCACGT
GGAGAAGGACTTCATTGCTTTCTGCTCTTCAACGCCACACAACGTGTCCTGGAGAGACAGCACAATGGGCTCTATCTTCA
TCACACAACTCATCACATGCTTCCAGAAATATTCTTGGTGCTGCCACCTAGAGGAAGTATTTCGGAAGGTACAGCAATCA
TTTGAAACTCCAAGGGCCAAAGCTCAAATGCCCACCATAGAACGACTGTCCATGACAAGATATTTCTACCTCTTTCCTGG
CAATTGAAAATGGAAGCCACAAGCAGCCCAGCCCTCCTTAATCAACTTCAAGGAGCACCTTCATTAGTACAGCTTGCATA
TTTAACATTTTGTATTTCAATAAAAGTGAAGACAAACGA
|
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|
Primary source |
RefSeq : NM_033306.2 (GI:73622124)
|
Name |
Caspase 4, apoptosis-related cysteine peptidase (CASP4), transcript variant gamma
|
Type of transcript |
mRNA
|
Organism |
Homo sapiens
|
Length |
1352 nt
|
Map |
11q22.2-q22.3
|
Location |
Chromosome 11 (NC_000011.9) strand : -
104813593...104813699 | 104815474...104815577 | 104817809...104817918 | 104819259...104819402 |
104820269...104820503 | 104821651...104821824 | 104822622...104822731 | 104825473...104825727 |
104827323...104827421 | 104839245...104839258 |
|
|
|
|
|
|
|
|
|
|
|
|
|
Exon(s) |
Start |
End |
Length |
is coding |
Exon 1b
|
1
|
14
|
14
|
1
|
Exon 2
|
15
|
113
|
99
|
1
|
Exon 3
|
114
|
368
|
255
|
1
|
Exon 4
|
369
|
478
|
110
|
1
|
Exon 5
|
479
|
652
|
174
|
1
|
Exon 6
|
653
|
887
|
235
|
1
|
Exon 7
|
888
|
1031
|
144
|
1
|
Exon 8
|
1032
|
1141
|
110
|
1
|
Exon 9
|
1142
|
1245
|
104
|
1
|
Exon 10
|
1246
|
1352
|
107
|
1
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Primary source |
NCBI : CCDS41704
|
Nucleotide |
CASP4, mRNA isoform gamma[NM_033306.2] : 275...1240
|
Length |
966
|
Location |
Chromosome 11 (NC_000011.9) strand : -
104815479...104815577 | 104817809...104817918 | 104819259...104819402 | 104820269...104820503 |
104821651...104821824 | 104822622...104822731 | 104825473...104825566 |
|
Start codon |
1
|
Translation |
NP_150649.1 |
|
|
|
|
|
|
|
|
|
|
|
|
1 |
GTTCCCTATG |
GCAGAAGCCT |
TTGTGATCTC |
ACCTGTTGGA |
ATGCACTAAT |
GTTTTCTGAG |
CCCCTTAAAT |
ATCTTGTCTA |
|
81 |
CATTCTTTTA |
AGAAGCTCTT |
CACCAACTGT |
CAGAAGGCAA |
CCACAGAAAA |
AAGCCACTTA |
AGGTGTTGGA |
ATCCCTGGGC |
|
161 |
AAAGATTTCC |
TCACTGGTGT |
TTTGGATAAC |
TTGGTGGAAC |
AAAATGTACT |
GAACTGGAAG |
GAAGAGGAAA |
AAAAGAAATA |
|
241 |
TTACGATGCT |
AAAACTGAAG |
ACAAAGTTCG |
GGTCATGGCA |
GACTCTATGC |
AAGAGAAGCA |
ACGTATGGCA |
GGACAAATGC |
|
321 |
TTCTTCAAAC |
CTTTTTTAAC |
ATAGACCAAA |
TATCCCCCAA |
TAAAAAAGCT |
CATCCGAATA |
TGGAGGCTGG |
ACCACCTGAG |
|
401 |
TCAGGAGAAT |
CTACAGATGC |
CCTCAAGCTT |
TGTCCTCATG |
AAGAATTCCT |
GAGACTATGT |
AAAGAAAGAG |
CTGAAGAGAT |
|
481 |
CTATCCAATA |
AAGGAGAGAA |
ACAACCGCAC |
ACGCCTGGCT |
CTCATCATAT |
GCAATACAGA |
GTTTGACCAT |
CTGCCTCCGA |
|
561 |
GGAATGGAGC |
TGACTTTGAC |
ATCACAGGGA |
TGAAGGAGCT |
ACTTGAGGGT |
CTGGACTATA |
GTGTAGATGT |
AGAAGAGAAT |
|
641 |
CTGACAGCCA |
GGGATATGGA |
GTCAGCGCTG |
AGGGCATTTG |
CTACCAGACC |
AGAGCACAAG |
TCCTCTGACA |
GCACATTCTT |
|
721 |
GGTACTCATG |
TCTCATGGCA |
TCCTGGAGGG |
AATCTGCGGA |
ACTGTGCATG |
ATGAGAAAAA |
ACCAGATGTG |
CTGCTTTATG |
|
801 |
ACACCATCTT |
CCAGATATTC |
AACAACCGCA |
ACTGCCTCAG |
TCTGAAGGAC |
AAACCCAAGG |
TCATCATTGT |
CCAGGCCTGC |
|
881 |
AGAGGTGCAA |
ACCGTGGGGA |
ACTGTGGGTC |
AGAGACTCTC |
CAGCATCCTT |
GGAAGTGGCC |
TCTTCACAGT |
CATCTGAGAA |
|
961 |
CCTAGAGGAA |
GATGCTGTTT |
ACAAGACCCA |
CGTGGAGAAG |
GACTTCATTG |
CTTTCTGCTC |
TTCAACGCCA |
CACAACGTGT |
|
1041 |
CCTGGAGAGA |
CAGCACAATG |
GGCTCTATCT |
TCATCACACA |
ACTCATCACA |
TGCTTCCAGA |
AATATTCTTG |
GTGCTGCCAC |
|
1121 |
CTAGAGGAAG |
TATTTCGGAA |
GGTACAGCAA |
TCATTTGAAA |
CTCCAAGGGC |
CAAAGCTCAA |
ATGCCCACCA |
TAGAACGACT |
|
1201 |
GTCCATGACA |
AGATATTTCT |
ACCTCTTTCC |
TGGCAATTGA |
AAATGGAAGC |
CACAAGCAGC |
CCAGCCCTCC |
TTAATCAACT |
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1281 |
TCAAGGAGCA |
CCTTCATTAG |
TACAGCTTGC |
ATATTTAACA |
TTTTGTATTT |
CAATAAAAGT |
GAAGACAAAC |
GA |
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>gi|73622124|ref|NM_033306.2|Caspase 4, apoptosis-related cysteine peptidase (CASP4), transcript variant gamma
GTTCCCTATGGCAGAAGCCTTTGTGATCTCACCTGTTGGAATGCACTAATGTTTTCTGAGCCCCTTAAATATCTTGTCTA
CATTCTTTTAAGAAGCTCTTCACCAACTGTCAGAAGGCAACCACAGAAAAAAGCCACTTAAGGTGTTGGAATCCCTGGGC
AAAGATTTCCTCACTGGTGTTTTGGATAACTTGGTGGAACAAAATGTACTGAACTGGAAGGAAGAGGAAAAAAAGAAATA
TTACGATGCTAAAACTGAAGACAAAGTTCGGGTCATGGCAGACTCTATGCAAGAGAAGCAACGTATGGCAGGACAAATGC
TTCTTCAAACCTTTTTTAACATAGACCAAATATCCCCCAATAAAAAAGCTCATCCGAATATGGAGGCTGGACCACCTGAG
TCAGGAGAATCTACAGATGCCCTCAAGCTTTGTCCTCATGAAGAATTCCTGAGACTATGTAAAGAAAGAGCTGAAGAGAT
CTATCCAATAAAGGAGAGAAACAACCGCACACGCCTGGCTCTCATCATATGCAATACAGAGTTTGACCATCTGCCTCCGA
GGAATGGAGCTGACTTTGACATCACAGGGATGAAGGAGCTACTTGAGGGTCTGGACTATAGTGTAGATGTAGAAGAGAAT
CTGACAGCCAGGGATATGGAGTCAGCGCTGAGGGCATTTGCTACCAGACCAGAGCACAAGTCCTCTGACAGCACATTCTT
GGTACTCATGTCTCATGGCATCCTGGAGGGAATCTGCGGAACTGTGCATGATGAGAAAAAACCAGATGTGCTGCTTTATG
ACACCATCTTCCAGATATTCAACAACCGCAACTGCCTCAGTCTGAAGGACAAACCCAAGGTCATCATTGTCCAGGCCTGC
AGAGGTGCAAACCGTGGGGAACTGTGGGTCAGAGACTCTCCAGCATCCTTGGAAGTGGCCTCTTCACAGTCATCTGAGAA
CCTAGAGGAAGATGCTGTTTACAAGACCCACGTGGAGAAGGACTTCATTGCTTTCTGCTCTTCAACGCCACACAACGTGT
CCTGGAGAGACAGCACAATGGGCTCTATCTTCATCACACAACTCATCACATGCTTCCAGAAATATTCTTGGTGCTGCCAC
CTAGAGGAAGTATTTCGGAAGGTACAGCAATCATTTGAAACTCCAAGGGCCAAAGCTCAAATGCCCACCATAGAACGACT
GTCCATGACAAGATATTTCTACCTCTTTCCTGGCAATTGAAAATGGAAGCCACAAGCAGCCCAGCCCTCCTTAATCAACT
TCAAGGAGCACCTTCATTAGTACAGCTTGCATATTTAACATTTTGTATTTCAATAAAAGTGAAGACAAACGA
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Exon number |
2
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Length |
99 nt
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Location |
Chromosome 11 (NC_000011.9) : 104827323...104827421 (-)
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Is part of |
CASP4, mRNA isoform gamma
(NM_033306.2)
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Sequence |
Show
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AAGCCTTTGTGATCTCACCTGTTGGAATGCACTAATGTTTTCTGAGCCCCTTAAATATCTTGTCTACATTCTTTTAAGAA
GCTCTTCACCAACTGTCAG
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Exon number |
3
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Length |
255 nt
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Location |
Chromosome 11 (NC_000011.9) : 104825473...104825727 (-)
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Is part of |
CASP4, mRNA isoform gamma
(NM_033306.2)
CASP4, mRNA isoform alpha
(NM_001225.3)
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Sequence |
Show
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AAGGCAACCACAGAAAAAAGCCACTTAAGGTGTTGGAATCCCTGGGCAAAGATTTCCTCACTGGTGTTTTGGATAACTTG
GTGGAACAAAATGTACTGAACTGGAAGGAAGAGGAAAAAAAGAAATATTACGATGCTAAAACTGAAGACAAAGTTCGGGT
CATGGCAGACTCTATGCAAGAGAAGCAACGTATGGCAGGACAAATGCTTCTTCAAACCTTTTTTAACATAGACCAAATAT
CCCCCAATAAAAAAG
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Primary source |
Uniprot : P49662
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Name |
Caspase-4
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Alternative name(s) |
ICE(rel)-II Protease ICH-2 Protease TX
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Synonym(s) |
CASP-4
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Organism |
Homo sapiens
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Length |
377 aa
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Protein existence |
---
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General annotation (Comments)
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top
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Catalytic activity
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Strict requirement for Asp at the P1 position. It has a preferred cleavage sequence of Tyr-Val-Ala-Asp-|- but also cleaves at Asp-Glu-Val-Asp-|-.
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Function
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Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves caspase-1.
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Ptm
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The two subunits are derived from the precursor sequence by an autocatalytic mechanism or by cleavage by Caspase-8.
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Similarity
|
Belongs to the peptidase C14A family.
Contains 1 CARD domain.
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Subunit
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Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a small and a large subunit (By similarity).
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Tissue specificity
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Widely expressed, with highest levels in spleen and lung. Moderate expression in heart and liver, low expression in skeletal muscle, kidney and testis. Not found in the brain.
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Biological process
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proteolysis [GO:0006508]
apoptosis [GO:0006915]
induction of apoptosis [GO:0006917]
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Cellular component
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intracellular [GO:0005622]
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Molecular function
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cysteine-type endopeptidase activity [GO:0004197]
protein binding [GO:0005515]
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With
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Uniprot accession
|
IntAct
|
TMEM147
|
Q9BVK8
|
EBI-1057327,EBI-348587
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VDAC3
|
Q9Y277
|
EBI-1057327,EBI-354196
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PSMB1
|
P20618
|
EBI-1057327,EBI-372273
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GSN
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P06396
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EBI-1057327,EBI-351506
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GCN1L1
|
Q92616
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EBI-1057327,EBI-356221
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USP9X
|
Q93008
|
EBI-1057327,EBI-302524
|
MDN1
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Q9NU22
|
EBI-1057327,EBI-1050480
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LSM10
|
Q969L4
|
EBI-1057327,EBI-373268
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CTNNBIP1
|
Q9NSA3
|
EBI-1057327,EBI-747082
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SNRNP200
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O75643
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EBI-1057327,EBI-1045395
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COPE
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O14579
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EBI-1057327,EBI-711301
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HIGD1A
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Q9Y241
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EBI-1057327,EBI-1051940
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SMC3
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Q9UQE7
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EBI-1057327,EBI-80718
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KIAA0776
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O94874
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EBI-1057327,
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CDK2
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P24941
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EBI-1057327,EBI-375096
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SNRPA1
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P09661
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EBI-1057327,EBI-876439
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UMPS
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P11172
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EBI-1057327,EBI-723452
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MSH6
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P52701
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EBI-1057327,EBI-395529
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SMC4
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Q9NTJ3
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EBI-1057327,EBI-356173
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EIF2S3
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P41091
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EBI-1057327,EBI-1054228
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HEATR2
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Q86Y56
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EBI-1057327,EBI-719966
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CCDC59
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Q9P031
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EBI-1057327,EBI-1047110
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SRPRB
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Q9Y5M8
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EBI-1057327,EBI-355393
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SLC25A1
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P53007
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EBI-1057327,EBI-359163
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UBXN1
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Q04323
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EBI-1057327,EBI-1058647
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MTHFD1L
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Q6UB35
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EBI-1057327,EBI-1046835
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NUP93
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Q8N1F7
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EBI-1057327,EBI-1042703
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SLC25A22
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Q9H936
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EBI-1057327,EBI-1050588
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SMC2
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O95347
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EBI-1057327,EBI-355822
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SMC1A
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Q14683
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EBI-1057327,EBI-80690
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PTPLAD1
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Q9P035
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EBI-1057327,EBI-359013
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VDAC1
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P21796
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EBI-1057327,EBI-354158
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SSR4
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P51571
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EBI-1057327,EBI-1054539
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MYCBPAP
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Q8TBZ2
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EBI-1057327,EBI-1391585
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DCTN1
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Q14203
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EBI-1057327,EBI-724352
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Alternative product(s)
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top
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Feature key |
Position
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Length
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Description
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Feature identifier
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Molecule processing |
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Propeptide
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1 - 80
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80
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Potential
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PRO_0000004596
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Propeptide
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271 - 289
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19
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Potential
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PRO_0000004598
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Region |
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Domain
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1 - 91
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91
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CARD
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P49662-DOMAIN-1
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Sites |
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Active site
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210 - 210
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1
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By similarity
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P49662-ACT_SITE-210
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Active site
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258 - 258
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1
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P49662-ACT_SITE-258
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Natural variations |
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Natural variant site
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47 - 47
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1
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D -> N (in dbSNP:rs56226603)
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VAR_061081
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Natural variant site
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284 - 284
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1
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E -> D (in dbSNP:rs55901059)
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VAR_061082
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Amino acid modifications |
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Modified residue
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83 - 83
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1
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Phosphoserine
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P49662-MOD_RES-83
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Experimental info |
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Mutagenesis
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258 - 258
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1
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C->S: Loss of activity
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P49662-MUTAGEN-258
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1 |
MAEGNHRKKP |
LKVLESLGKD |
FLTGVLDNLV |
EQNVLNWKEE |
EKKKYYDAKT |
EDKVRVMADS |
MQEKQRMAGQ |
MLLQTFFNID |
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81 |
QISPNKKAHP |
NMEAGPPESG |
ESTDALKLCP |
HEEFLRLCKE |
RAEEIYPIKE |
RNNRTRLALI |
ICNTEFDHLP |
PRNGADFDIT |
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161 |
GMKELLEGLD |
YSVDVEENLT |
ARDMESALRA |
FATRPEHKSS |
DSTFLVLMSH |
GILEGICGTV |
HDEKKPDVLL |
YDTIFQIFNN |
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241 |
RNCLSLKDKP |
KVIIVQACRG |
ANRGELWVRD |
SPASLEVASS |
QSSENLEEDA |
VYKTHVEKDF |
IAFCSSTPHN |
VSWRDSTMGS |
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321 |
IFITQLITCF |
QKYSWCCHLE |
EVFRKVQQSF |
ETPRAKAQMP |
TIERLSMTRY |
FYLFPGN |
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>sp|P49662|CASP4_human Caspase-4
MAEGNHRKKPLKVLESLGKDFLTGVLDNLVEQNVLNWKEEEKKKYYDAKTEDKVRVMADSMQEKQRMAGQMLLQTFFNID
QISPNKKAHPNMEAGPPESGESTDALKLCPHEEFLRLCKERAEEIYPIKERNNRTRLALIICNTEFDHLPPRNGADFDIT
GMKELLEGLDYSVDVEENLTARDMESALRAFATRPEHKSSDSTFLVLMSHGILEGICGTVHDEKKPDVLLYDTIFQIFNN
RNCLSLKDKPKVIIVQACRGANRGELWVRDSPASLEVASSQSSENLEEDAVYKTHVEKDFIAFCSSTPHNVSWRDSTMGS
IFITQLITCFQKYSWCCHLEEVFRKVQQSFETPRAKAQMPTIERLSMTRYFYLFPGN
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Primary source |
Uniprot : A2NHL8
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Name |
Caspase 4, apoptosis-related cysteine peptidase [submitted name]
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Alternative name(s) |
Caspase 4, apoptosis-related cysteine peptidase, isoform CRA_b [submitted name] Mih1/TX isoform alpha [submitted name]
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Synonym(s) |
|
Organism |
Homo sapiens
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Length |
377 aa
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Protein existence |
---
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General annotation (Comments)
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top
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Similarity
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Belongs to the peptidase C14A family.
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Biological process
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proteolysis [GO:0006508]
apoptosis [GO:0006915]
regulation of apoptosis [GO:0042981]
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Cellular component
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intracellular [GO:0005622]
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Molecular function
|
cysteine-type endopeptidase activity [GO:0004197]
protein binding [GO:0005515]
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With
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Uniprot accession
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IntAct
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Alternative product(s)
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top
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Feature key |
Position
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Length
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Description
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Feature identifier
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1 |
MAEGNHRKKP |
LKVLESLGKD |
FLTGVLDNLV |
EQNVLNWKEE |
EKKKYYDAKT |
EDKVRVMADS |
MQEKQRMAGQ |
MLLQTFFNID |
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81 |
QISPNKKAHP |
NMEAGPPESG |
ESTDALKLCP |
HEEFLRLCKE |
RAEEIYPIKE |
RNNRTRLALI |
ICNTEFDHLP |
PRNGADFDIT |
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161 |
GMKELLEGLD |
YSVDVEENLT |
ARDMESALRA |
FATRPEHKSS |
DSTFLVLMSH |
GILEGICGTV |
HDEKKPDVLL |
YDTIFQIFNN |
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241 |
RNCLSLKDKP |
KVIIVQACRG |
ANRGELWVRD |
SPASLEVASS |
QSSENLEEDA |
VYKTHVEKDF |
IAFCSSTPHN |
VSWRDSTMGS |
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321 |
IFITQLITCF |
QKYSWCCHLE |
EVFRKVQQSF |
ETPRAKAQMP |
TIERLSMTRY |
FYLFPGN |
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>sp|A2NHL8|A2NHL8_human Caspase 4, apoptosis-related cysteine peptidase [submitted name]
MAEGNHRKKPLKVLESLGKDFLTGVLDNLVEQNVLNWKEEEKKKYYDAKTEDKVRVMADSMQEKQRMAGQMLLQTFFNID
QISPNKKAHPNMEAGPPESGESTDALKLCPHEEFLRLCKERAEEIYPIKERNNRTRLALIICNTEFDHLPPRNGADFDIT
GMKELLEGLDYSVDVEENLTARDMESALRAFATRPEHKSSDSTFLVLMSHGILEGICGTVHDEKKPDVLLYDTIFQIFNN
RNCLSLKDKPKVIIVQACRGANRGELWVRDSPASLEVASSQSSENLEEDAVYKTHVEKDFIAFCSSTPHNVSWRDSTMGS
IFITQLITCFQKYSWCCHLEEVFRKVQQSFETPRAKAQMPTIERLSMTRYFYLFPGN
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Primary source |
Uniprot : A2NHM0
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Name |
Caspase 4, apoptosis-related cysteine peptidase, isoform CRA_c [submitted name]
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Alternative name(s) |
Mih1/TX isoform gamma [submitted name]
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Synonym(s) |
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Organism |
Homo sapiens
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Length |
321 aa
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Protein existence |
---
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General annotation (Comments)
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top
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Similarity
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Belongs to the peptidase C14A family.
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Biological process
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proteolysis [GO:0006508]
apoptosis [GO:0006915]
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Molecular function
|
cysteine-type endopeptidase activity [GO:0004197]
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With
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Uniprot accession
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IntAct
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Alternative product(s)
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top
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Feature key |
Position
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Length
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Description
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Feature identifier
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1 |
MADSMQEKQR |
MAGQMLLQTF |
FNIDQISPNK |
KAHPNMEAGP |
PESGESTDAL |
KLCPHEEFLR |
LCKERAEEIY |
PIKERNNRTR |
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81 |
LALIICNTEF |
DHLPPRNGAD |
FDITGMKELL |
EGLDYSVDVE |
ENLTARDMES |
ALRAFATRPE |
HKSSDSTFLV |
LMSHGILEGI |
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161 |
CGTVHDEKKP |
DVLLYDTIFQ |
IFNNRNCLSL |
KDKPKVIIVQ |
ACRGANRGEL |
WVRDSPASLE |
VASSQSSENL |
EEDAVYKTHV |
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241 |
EKDFIAFCSS |
TPHNVSWRDS |
TMGSIFITQL |
ITCFQKYSWC |
CHLEEVFRKV |
QQSFETPRAK |
AQMPTIERLS |
MTRYFYLFPG |
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321 |
N |
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>sp|A2NHM0|A2NHM0_human Caspase 4, apoptosis-related cysteine peptidase, isoform CRA_c [submitted name]
MADSMQEKQRMAGQMLLQTFFNIDQISPNKKAHPNMEAGPPESGESTDALKLCPHEEFLRLCKERAEEIYPIKERNNRTR
LALIICNTEFDHLPPRNGADFDITGMKELLEGLDYSVDVEENLTARDMESALRAFATRPEHKSSDSTFLVLMSHGILEGI
CGTVHDEKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGANRGELWVRDSPASLEVASSQSSENLEEDAVYKTHV
EKDFIAFCSSTPHNVSWRDSTMGSIFITQLITCFQKYSWCCHLEEVFRKVQQSFETPRAKAQMPTIERLSMTRYFYLFPG
N
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