(APOL1) apolipoprotein L, 1 [Homo sapiens] |
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Gene
Transcript(s)
Exon(s)
Protein(s)
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Accession
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10796
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Official symbol
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APOL1
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Official name
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apolipoprotein L, 1
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Gene type
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gene with protein product
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Organism
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Homo sapiens
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Location
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Chromosome 22 (NC_000022.10) : 36649116...36663576 (+)
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Map
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22q13.1
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Length
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14461 nt
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NM_003661.3
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APOL1, mRNA isoform 1
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NM_145343.2
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APOL1, mRNA isoform 2
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NM_001136540.1
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APOL1, mRNA isoform 3
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NM_001136541.1
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APOL1, mRNA isoform 4
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Accession
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Name
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Organism
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Length
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O14791
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Apolipoprotein L1
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Homo sapiens
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398 aa
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Q2KHQ6
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APOL1 protein [submitted name]
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Homo sapiens
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398 aa
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B1AH95
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Apolipoprotein L, 1 [submitted name]
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Homo sapiens
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141 aa
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Synonyms |
APOL-I; APO-L; APOL
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Alternative name(s) |
apolipoprotein L-I
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Summary |
This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
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Related Articles in PubMed
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Go to ensembl
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1 |
TGACTTTCAC |
TTTCCCTTTC |
GAATTCCTCG |
GTATATCTTG |
GGGACTGGAG |
GACCTGTCTG |
GTTATTATAC |
AGACGCATAA |
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81 |
CTGGAGGTGG |
GATCCACACA |
GCTCAGAACA |
GCTGGATCTT |
GCTCAGTCTC |
TGCCAGGGGA |
AGATTCCTTG |
GTAAGTTGGG |
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161 |
GACAGTTGAC |
CTGCCTCCAT |
CTTATTCTCA |
CAGCTTTTGT |
AGATAAGCTG |
GGAGAGGTTA |
GGTGACTGGT |
TCAGATAGAC |
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241 |
AGGAAAGTAG |
CGGCAAAGCC |
TGGATTTGCA |
CCCAGGCTTG |
AGTCTGATTG |
CTTCCCCTCT |
CCTGCTGGGC |
TCTTAAACTA |
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321 |
TAGAGGGTTG |
GGGAAACAGC |
TCAGATGGGT |
TCACAAAGCT |
CCCTGGGCTC |
AGCCCTGGTT |
TTGACTGCTG |
AGACACGACT |
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401 |
GAGTGAACCC |
AGAAGGAAGG |
TTTGTGTTGG |
GGGTGCCCAT |
CTCTTTGGGA |
AATTTGAAGG |
AACCAAAGAA |
GGTGGAGGAG |
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481 |
AGGAGGTGAC |
CCAGATCCCA |
GCCTGTTCTT |
ATGGCCAGGC |
CACACCAAGG |
CTGGCCCCAG |
GGTGCTGCTG |
CTGAGGCCCA |
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561 |
ATGGGGGCAA |
CAGAATTTTT |
TTTCAGGTAC |
AAGGAGTTCA |
GAGGTCATCT |
CACCCACCCT |
GAGTCTGAGC |
ACCAACTTGT |
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641 |
GCCAGGCCCT |
GTGGGGAAAC |
TGAGGCCCTG |
GGAGCGGAAT |
GACTTGCCCA |
GGGTCCCGTG |
TCAGGAGGCT |
GAGCAGGTAG |
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721 |
ATCATAGGAC |
TCCACGTCTC |
TGGCCCTCAC |
CTCTGTCCCT |
CTGTTCAGAC |
TTCTGGGGTG |
ATGGAGAAGA |
AACAGGCTGT |
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801 |
GCTGTGTCCC |
TAATGGGAAA |
CGTGGCTGAG |
ACAGGGGAGT |
GAGAAGGGTG |
CGTTGCAGAA |
TGGTGCCTGT |
GGCATGATGC |
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881 |
CAGCTTTGCA |
ATCATGAGAT |
TCAAAAGCCA |
CACTGTGGAA |
TTGTGAGTAT |
AACTACAGGA |
GTGAGAGCTT |
AGATCTCTGT |
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961 |
GTTCATAGAA |
GGAGAATCAA |
ACCTGGAAAC |
TTTTGGATTA |
TTAAAATCAA |
ACATTTTTGC |
TTCAATATTA |
GAGTCACAAG |
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1041 |
GGCAGATGTT |
GGCCTCCCCT |
CTGCCCTCCA |
AGAGCTGTGT |
GACTCTGGGA |
AATTCACCTC |
CCCTCCCAGC |
CTGAGTATTT |
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1121 |
TCCCCTGTAA |
AAAACCTGAT |
AGAGCTGCCA |
AAAGTCCATG |
AAATCAGGGG |
GGTAATTTCT |
GTGAAATCTG |
AGTCATGGTC |
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1201 |
TTATTTGTTC |
TTCACCAAAA |
AGAGATGATG |
AAGCCTGTAA |
CCCCAGTGCT |
GTGGGAGGCA |
GAGGCGGGAG |
GATGACTTGA |
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1281 |
GGCCAGGAGT |
TCAAGACAGC |
CTGGGAAACA |
CAGGAGATGC |
TGTCTCTATG |
AAATCAAAAA |
TTAACAAATT |
AGCCCAGCAT |
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1361 |
GGTAGTGTGT |
ACCTGTAGTC |
CCAGCTACTC |
AGAAGGTTGA |
AGGAGGCGGA |
TCACTTGAGC |
CCAACAGATC |
TAGGCTGCAA |
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1441 |
TGAGCTAGGA |
TGGTGTCAAA |
GCCCTGCAGC |
CTGGGTGACA |
GAGCAAAACT |
GTTTATTAAA |
AACTAAACGA |
AAGGCCGGGC |
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1521 |
GCGGTGGCTC |
ACGCCTGTAA |
TCCCAGCACT |
TTGGGAGGCC |
AAGACAGGTG |
GTCACGAGGT |
CAGGATATCG |
AGACCATCCT |
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1601 |
GGCTAACATG |
GTGAAACCCT |
GTCTCTACTA |
AAAATACAAA |
AAAATTAGCC |
GGGTGTCGTG |
GCGGGCACCT |
GTAGTCCCAG |
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1681 |
CTACTCGGGA |
GGCTGAGGCA |
GGAGAATGGC |
GTGAACCCGG |
GAGGCAGAGC |
TTGTAGCGAG |
CCTAGATCGC |
CCCACTGCAC |
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1761 |
TCCAGCCTGG |
GTGATAGAGC |
GAGACTCCAT |
TTCAAAAAAA |
AAATGAAATG |
AAAATGGTGA |
TTTCTCAGGA |
GGAGCACACT |
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1841 |
GTCTCAACCC |
CTCTTTTCCT |
GCTCAAGGAG |
GAGGCCCTGC |
AGCGACATGG |
AGGGAGCTGC |
TTTGCTGAGA |
GTCTCTGTCC |
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1921 |
TCTGCATCTG |
GTGAGCTTGG |
CTCAGAGCCC |
TGAGGCGGGA |
GGGAGGGCTC |
CCTGTCTGGG |
CTGCACAATT |
GGACTGGGCT |
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2001 |
TGGGCTGGGC |
CAGGGCCATC |
TGGGCTTCTT |
CTAGGAACCA |
AAGTCACTTC |
CCGGAATTGA |
CCAACCGGCA |
GACTCGCCCA |
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2081 |
GGGAGGACCC |
GCTGTATCCT |
AGTTGAGGCT |
AACGGTCAAT |
ATCCGGCCTC |
AATATTCAGC |
AGAGGCTCCA |
GGTCAGGGTC |
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2161 |
TGAGCCAGGC |
CAACAATGAC |
CAAGGAGGAT |
GGGATCCAGG |
GTGCAGCTCC |
TCACAAGTGT |
CGGGGGAATC |
CGAGGCACCA |
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2241 |
GCTCTCTCTA |
CCCTCCTGCT |
CCTCTGCTCT |
CTCCTGGTCC |
TCCTGTGTCC |
TCATGGCTCA |
TGAGATGGTG |
TTGAGATGGC |
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2321 |
TCCCCTGGCC |
TAGGGGATCA |
CACAGTGAAC |
AAAGCAGGAA |
GAAGGCGAAG |
GGATGCCCCT |
CTCCTGTCAC |
CCTTGTCCCT |
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2401 |
TACAGCAAGA |
AGGGCCCAGA |
CGCCCCTCTG |
CATACTCCCC |
TGGTGAACTG |
CTGCCCAGGA |
CTGGGTCCCC |
CTTTTACCCT |
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2481 |
TGCTGCATGG |
AGTCCCCAGA |
AGACAAACAT |
CTGTGTGTCT |
GAACCCTGAG |
ACAAAGGCAG |
GAAAGGGAAA |
GAGGGAGGCG |
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2561 |
AGTGGCTTTT |
GAGGAGGGGG |
CTTTAGTATG |
AGAGCTGGAG |
GATGGAACCC |
CATCAGGGGG |
CCCGGGAACC |
ACTGAGCTGT |
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2641 |
TAAAATAAAG |
TCTGCAAACA |
AAGACCAGCT |
GCTGGAAGTG |
GGTGTGCCAG |
GGAGTGCGCA |
GAGACACACG |
GTGAGAAAAG |
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2721 |
AACAATGGTA |
ATGCTTGGAG |
CCGCCCCTAA |
CTGGGATGGG |
CCTGAAATGG |
TATTGTTATT |
ATTTATAGTA |
TCATTATTAG |
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2801 |
TCATTTTCAT |
CTTATTTGTA |
CCCTCCCTCT |
ATCTCTCCTC |
TCCACCTTTT |
CCTAACATTC |
TATCACCAGT |
TTTATGTCTT |
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2881 |
CCATTAGCAA |
CTTTGTAGCT |
GTAAATAATT |
TACTTACAAC |
TTTCATATAC |
CCTCAGTTGT |
ACCCAGTATT |
TCTTAACTTC |
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2961 |
CCTCTTTAAA |
AAAATGATAA |
TATTAATCCT |
CCTTCTCCTT |
CGTTCAGTGC |
TTCACATCCC |
AACTGCTACC |
TTTGTGCTTT |
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3041 |
AAATTTTGTA |
CTAATTGGTG |
TTGATAACAA |
GTATATTTAG |
TTCTCATATT |
TATATGTTGT |
GTATATGTTT |
TGGTTTTTTT |
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3121 |
TTGTCTTAAA |
CAAGAGACTA |
CTGAGAGCCA |
GTAAGACTGA |
AAGAAAGGGC |
ATCTTCATAT |
ACTGCTAGTT |
TGAGTGTGAA |
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3201 |
TTGGTACAAT |
TTGCCTGCAG |
TGTGGCTCTA |
GGTATAAAGC |
CTTTTGAGTT |
GTTGATAGCC |
TCTGACCTGC |
TCATTCTACT |
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3281 |
CCTACAAATA |
TCTTAAGGAA |
ATAATCTCAA |
ATGTGGGCAA |
AGTTTTATGC |
GAAGAAGGAT |
GTTCTTTGTA |
GCATAATTTA |
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3361 |
TATGAGGAAT |
TAGAAACACC |
CTGAGGTCCA |
TCAGCTAGGG |
AAAGACAGCA |
GAGGGGACAG |
GGCAGCACCA |
GGAGGGCTTG |
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3441 |
GCAGCCACAG |
CAGGGGCTGG |
GCTGGCATCT |
GGCAAGATCC |
AGGTCTTTGT |
GGGACAAAGA |
ATCTTAGAGA |
AGCAACGGGG |
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3521 |
ACACAGGCTG |
TCCAGTGCAG |
CACCAGTGAA |
TTCACCAAGA |
TGAAGAGTTG |
AGCACAGAGT |
GTGAGACAAG |
GATTTGCAAT |
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3601 |
GAGGAGTCAT |
TTACCATGAG |
CGTGTATACA |
TGACTCAATA |
TTGTATATTT |
AAGGGAGTAG |
AGCACAGTCA |
TTGAAAACAT |
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3681 |
GGGGTTGAAG |
CAGAAGTCCT |
GGCTCTAGCA |
CTATTGTAAA |
AACACTGGCA |
AGTTCCCTAA |
CTTTTGTGGA |
TTCCTCTGTG |
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3761 |
TTTGAATGGG |
AAAGTGGTAC |
CCATCTCCTG |
GCCTGTGTGT |
GATCATCGAA |
TGAGACACAT |
GTAAGAGGCT |
CTGCACATCG |
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3841 |
CAGACATGCA |
ATACACACTG |
GCTATCACCA |
GCTAGTTATC |
ACACATGCTC |
CCAGGCCCTG |
GTCATTGTCA |
GAACCTTCCT |
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3921 |
CCCCATCTCT |
ATTTCTGTGT |
ATAGACTCTG |
TAGTTTCTGT |
AATGATCAGA |
TGGCTGCCCG |
TCCTCTGATT |
ATCTTCTCCT |
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4001 |
CATACCCCAA |
CAGGATGAGT |
GCACTTTTCC |
TTGGTGTGGG |
AGTGAGGGCA |
GAGGAAGCTG |
GAGCGAGGTG |
AGTGTCTGCA |
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4081 |
AATAGCAGAT |
GATGGGGGCT |
CAGTGATAGA |
CAAACAATCT |
GGTTTAGGTT |
GGTCTTGGTG |
TTTGCTTCCA |
CCCCAGAGAG |
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4161 |
ATTTGCAGAG |
CCCCGGCTGC |
TCAAGCAAGC |
CTCCCTCTGT |
CCACTGGTGG |
CTCACATTTG |
ATCCCACAAT |
TTGTTTTCTC |
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4241 |
CTCCTCAAGG |
GTGCAACAAA |
ACGTTCCAAG |
TGGGACAGAT |
ACTGGAGATC |
CTCAAAGTAA |
GCCCCTCGGT |
GACTGGGCTG |
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4321 |
CTGGCACCAT |
GGACCCAGGT |
AGGCTCACCT |
CCTCTTCCCT |
GCTGGTTCCT |
ACTCGCACTT |
AGAATGGAGG |
GTGGCACCTC |
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4401 |
CACAGCTGAG |
TGAGCCCCAG |
AAGAACCCGG |
ATGGACTAGG |
AGGCCAATGA |
GTCTGCCCAA |
AGCAGCAGAA |
GAGGTCACGT |
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4481 |
GGAGTCCCCC |
GACCCAGGGG |
TCTGGGGGTC |
ATCTGCATCC |
TGACCTCTCC |
TTAGGGTGAC |
ACGGCCCAGG |
TGCCCACTTC |
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4561 |
CTCCCTACCC |
TGGCACCTAG |
CAAATGACTC |
AAGTGGGGCA |
GGACATCCTT |
GGGGAAGTGG |
AATCAGCGGG |
GGGGGGGGGG |
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4641 |
AGTGTGGGGA |
GAGCAGGGTC |
CAGGAGGAGA |
GGAGGGCTGG |
GAGAGGAGGT |
TGACCAGCAG |
CCCCGACCTG |
TCACCTCCCG |
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4721 |
CTCTGCTCCA |
AGCTGACCCT |
GGGGTGTTTC |
CACCTGAGGC |
TGGTCCCCTC |
CCTCCAGCTC |
TTGCCCTGCC |
CTAGCCCCTT |
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4801 |
TGCTCTGAGT |
GGCCCTGTGG |
GAATGTATCG |
GGCCTGATTC |
AGCTTCCAGC |
TTAACTGGAC |
CCCGGTCTGT |
CCTTTGCCAC |
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4881 |
ATCCCCTCTG |
TGTGACCTGG |
CGCTCCTTAC |
CTCCCTTCTC |
CTGTACCATG |
AGAATAATAT |
TTCCCCATGT |
TGTCTTGAGG |
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4961 |
ATCAAATATA |
ACACGGCTAC |
CTGGCCTGGC |
CAGTGCCTGC |
CACACAATAG |
GGCCTCCCTA |
AGGGCTGGTT |
CCCATCCCCT |
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5041 |
CTACTGGTCC |
CCTGTTGATT |
CCAGGTGGAA |
GCCACCCCGT |
CCCCCCCCAG |
CTGTGTTAGG |
GCACCCGCCC |
TGCCCTGCCC |
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5121 |
ATCACAAGCA |
CCTGCTTACC |
AGGGATGACT |
GCCTCAGGCA |
GGGGCTGAGT |
TCAGTCATCT |
AAAATACCCC |
CGGTCAAAGA |
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5201 |
AAAATCTGAG |
GCCCAATAGA |
ATTTTAAAGA |
GTTAATTGAG |
TAAGAAAGGA |
TTGCTGAATT |
GGGAAACAGC |
AAACTGGAGG |
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5281 |
AGGCTTCGTG |
CTATGGTGAA |
AAAGTGTCGG |
AGACAAGGTT |
TATCGGGTGA |
ATATGAAACT |
GCAGTAAGGA |
CATTATTTGA |
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5361 |
TTGGTTGCAC |
TTACAAAACT |
GCCTGTTTGG |
GTTTACCTTG |
TTGGAAAATC |
CCTGGTCACG |
TTGGTGCCAG |
TGTGAGTTTA |
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5441 |
GGGAGGTCTC |
CGAATACAGG |
TGAGACCGGA |
ACTTAGCCTT |
GCCCAGGTTT |
TTGATGCTGA |
AGAGAGAAAA |
AAGTCAAAGC |
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5521 |
AAAAGCAAAT |
CAGCTTTTAG |
TGCAAAACAG |
AAGTGCAGGC |
TCAGGGGTGG |
GAGTGCAGGC |
GGACTCAGAA |
GAGCCAGTCG |
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5601 |
GGCCCAGTGG |
AGTTTGGGGT |
TCTTGTCTTT |
GCTGGTTTAT |
TAAATTAAGG |
TGTGGAGTAA |
GCATAAGGAT |
TTCTGGGAAG |
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5681 |
AGGTGGGGAT |
TTCTTGGAAT |
TGGGAGGGCA |
ATGCAGTTTT |
GTACCAAACA |
TGGGCATACA |
TGGAACGGCT |
GTGGTGCGGG |
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5761 |
TGGGTGTGGG |
GTTTAGTGAG |
ACAAGGAGGG |
TATGATTGAG |
TGTGAGGCAA |
AACGTGGGTC |
AGACCCAGCG |
CCGAGTTGGA |
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5841 |
TCTCACTGGT |
CTTAGCTGAA |
TTGGCCACTT |
CCTGTTTGTC |
AGGATCCTGT |
GGGCCCATCC |
CCTCCCCCTG |
TCCCTACAGG |
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5921 |
TGGTTTCAGC |
AACTCCTTCT |
GTGTCTGTCA |
TGTGAACCTG |
CTGCCTGGAG |
TTCTTGTTTC |
TTCTGTGACC |
TCCCAGTATC |
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6001 |
CACATCTCAG |
CATGGCCCTC |
TGTCAGCTGG |
CTTTAAGTTT |
TGTTTGTATC |
TAACAGAAGT |
ACCCATCTGA |
TATGACCCCA |
|
6081 |
GTTGAGTTTC |
CCATAGCTTG |
CAGTTTCAGG |
GGGTTACAGC |
TGTTCTAAAG |
GCCTCGTAGG |
TATTGCCTGT |
CCAGGAATGT |
|
6161 |
TTCAGGGCTG |
GTTTTTGTTT |
TAATTTTGCT |
TTTATATCCA |
CCAGCCCCAC |
CACATCAAGA |
AATACACAGA |
TTTAGTGCCA |
|
6241 |
GAGGTTCCTT |
CCATCCAAAC |
CTGGGTTTCC |
TTCCTCCTTT |
TGGTGAAGAA |
GGAAAAAGAA |
AAAACAAGAC |
AATCGCTCGC |
|
6321 |
CCAGCCAAGT |
CAGCATTGCG |
TTCATTTCCC |
TAAGCCCCAT |
TTCCTCAGGA |
GGGCTTCCTC |
CCCTTACAGA |
GTTGCCACGG |
|
6401 |
CAACCAAGTC |
AGCTCTGCTC |
AGGAGCCGCC |
CTGGACAGCA |
AACTGGGCTG |
TGCTGAGTCC |
TGTCCAAGAC |
GAGGGGAGGG |
|
6481 |
CAGGGAAGAT |
TAGAAGCCGA |
GAGCACTCAG |
CCGACCCCGG |
AATCCTTACG |
AAGGGCTGGG |
CTGGGGGACT |
GAGGAAAAAC |
|
6561 |
TCTCCCCCCA |
AAACAAGATG |
ATCTGTGGTT |
TAATAACAGG |
CCCAGCTGGG |
TCCAGAGGTG |
ACAGTGGAGA |
GCCGTGTACC |
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6641 |
CTGAGACCAG |
CCTGCAGAGG |
ACAGAGGCAA |
CATGGAGGTG |
CCTCAAGGAT |
CAGTGCTGAG |
GGTCCCGCCC |
CCATGCCCCG |
|
6721 |
TCGAAGAACC |
CCCTCCACTG |
CCCATCTGAG |
AGTGCCCAAG |
ACCAGCAGGA |
GGAATCTCCT |
TTGCATGGTA |
GTTGTACTCA |
|
6801 |
ATGCTGTGGA |
GTTTGAGACA |
TTATTTTTAA |
ACTTTAAATA |
GCCCCACAGG |
TAAGCTATAA |
GGGAGAATGC |
AGAGACCACA |
|
6881 |
GGCATTTTCA |
AAACATAAGG |
AGTTTTAATG |
TTAAGGAGTT |
TAAGGAGAAT |
GTCAAAGAAA |
CATTGGCCTT |
GGAGTCAAAT |
|
6961 |
CCTGAGCTTC |
CTGCTTGATG |
GTTTTGGGCG |
GTGACTCTCG |
CTGTCTGGAT |
TTTACTTTCT |
TCATCTGTGA |
ATTAAGAATG |
|
7041 |
AGGTGGCCGG |
GCACTGTGGC |
TCACGCCTGT |
AATCCCAACA |
TTTGGGAGGC |
CGAGGCGGGC |
AGATCACAAG |
GTCAGGAGAT |
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7121 |
CGAGACGATC |
CTGTCTAACA |
CGATGAAACC |
CTGTCTCTAC |
TAAAAATACA |
AAAAAAATTA |
CCAGGCCTGG |
TGGCAGGCGC |
|
7201 |
CTGTAGTCCC |
AGCTACTCAG |
GAGGCTGAGG |
CAGGAGAATG |
GCATGAACCC |
AGGAGGCAGA |
GCTTGCAGTG |
AGCCAAGATC |
|
7281 |
GCACCACTGC |
ACTCCAGCCT |
GGGTGAGAGA |
GCAAGACTCC |
ATCCCCCCAA |
AAAAAAGAAT |
GAGGTCTCTT |
GTGTGTGCAC |
|
7361 |
GGCAAGAAAC |
AATTTTACAT |
CATGCCTCAG |
TGCACACACA |
AATACATACT |
GGTCCCCAGT |
TCCTTATCTG |
CAATTCCATA |
|
7441 |
ATTCCCAGAT |
CCCTGCAAAC |
CACACGTTTT |
GGTGGCAGCT |
GACTTCAGGA |
GTAATCCTGC |
TCTGTACTGA |
CTTGAGTTCT |
|
7521 |
TTGTAGACCT |
ACCATTATTT |
TTTACATTTA |
ATGTGAATAT |
TTGCTTGTTT |
CACTGTTGAA |
ACATGTGTGG |
GTGTGATTAC |
|
7601 |
AGGGAGCAGT |
CCAGCCTCTG |
CTGGGAATGG |
TCAGGAATAT |
ACCATATGCA |
CCCCGTGTCC |
TTTCTAAAAT |
AGTGGAAATT |
|
7681 |
CTGAATGCCT |
AAACACATCT |
GGATTCCAGG |
AATTTACATT |
AAGGGATATA |
TATTTGAAAT |
AACCCACAAA |
AACAATACTC |
|
7761 |
ACCCCTGCTA |
CGCTTGGTAC |
ACTCTGATAT |
TTTCAAATTG |
ATTTTCTTTT |
TAAAATGCTG |
CTTTTGAACC |
AATAATTTCA |
|
7841 |
TAACCCAATG |
ATGTGTTGAT |
ATTCACATTT |
TGAAGACACT |
GGTATAAAGT |
GTTTGACCCA |
ACAGGCATGT |
GGCAGATGGA |
|
7921 |
AGTGATCACT |
GGGATGTTTC |
CACTTCCTTG |
GCCTGGAAGG |
CTCACTTCAT |
GTTGGTGCTG |
AGCTGAAAAG |
GATTCATTCC |
|
8001 |
TCTCCAAAGC |
ACCATGGCAC |
TCCCCTGGTG |
TTTCAATGTT |
CTCAGGCTGC |
CATAGTAAAA |
TATCACAGGC |
TGGGTGACTT |
|
8081 |
CAACATCTGG |
CTTTTATTTT |
CTCACAGATC |
CAGAGGCAAG |
AAGTCCAAGG |
TGAAGGTGCC |
AAAAGGGTTG |
GAGTCTGGGG |
|
8161 |
AGGACTCTCT |
TGCTGGCTTA |
TGGAAGCTGC |
CTTTGCACTG |
TGTGCTCACA |
CAGTCTTCTT |
GTGTCCCTTT |
CTGTTCTTAC |
|
8241 |
AATAGGACAC |
TAGCCCTCTA |
ATAGAATTAG |
AGCCCTACCC |
TTGTGATCTC |
ATTCAGTCTT |
AATTGCTTCC |
TTAAAGGCCA |
|
8321 |
GATCTCCAAA |
TGTAGTCACC |
TGAGTTTAAA |
GCTTCAGCAT |
ATGAATTTTG |
GGGGCACACA |
ATTCCCTCTA |
TAGCACTAAT |
|
8401 |
GACTCCATAA |
AACAAGTCCC |
ACATCACAGC |
TGTCCAGGAA |
AATTAACATG |
TAGTCATCTC |
TTATGCAATG |
GCTGTTATGC |
|
8481 |
ACTCCCACAC |
TTTCCTCCAA |
CCTTATCCTT |
TCTTCTTTCC |
AACTAGAGAG |
CAGTATCTTT |
ATTGAGGATG |
CCATTAAGTA |
|
8561 |
TTTCAAGGAA |
AAAGTGAGCA |
CACAGAATCT |
GCTACTCCTG |
CTGACTGATA |
ATGAGGCCTG |
GAACGGATTC |
GTGGCTGCTG |
|
8641 |
CTGAACTGCC |
CAGGTAAGCT |
CCATGGGGTT |
ACCTCCATTG |
GGCACTCCGG |
CGATGCCACC |
CAGCTCTCCC |
CTGGGCTAGT |
|
8721 |
TTTCCCTGAC |
AGGCACACCT |
CCTCCAGGCA |
GCCCCCTCTG |
CTGGGCTTGA |
GGATGACCTT |
CTTGGCACTC |
CAGGAAGAAT |
|
8801 |
ATTTCCTCCA |
TGTCCTTCGC |
TGGCAGTGAG |
TAGCCTCAGG |
CTGAGGGGAT |
AGGAAGCCCA |
CAGGAACAGG |
GTCATTTCTG |
|
8881 |
CCATCTGCTG |
GTGATGGGAA |
CTTTGCCAGT |
TACTTTCTCA |
CTTTCAGCCT |
TTCTTCATCA |
ATGGAGTTTT |
ATTGTGAGAA |
|
8961 |
AAATGAGATC |
GTGCATGTAA |
AGTGCTTAGC |
ATAATGACTG |
ACACACAGTA |
GGTGCACAGT |
TAACGTTAAC |
ATCTTACAAG |
|
9041 |
CTTGGTGGAA |
ACAGAACCAG |
GGTTAAGGAT |
CTTCTTCTTG |
AAGATGGGAG |
CCCAGCAGGA |
CTTGACCTTT |
GGGACAAGTC |
|
9121 |
AGAAAAATCC |
TGACCTAACC |
AATGTGTGTT |
CCTGGGGATG |
CTGGCTGGAG |
CCCTTTTTCT |
CATCTGAGGA |
ATTCCATAAA |
|
9201 |
CACGGCAGGA |
CCCTTCTGCT |
GGTCCAGGAT |
GCCGAGAGGC |
TGGAGTGGAG |
TTGCACAGCG |
CTGGGTCTCT |
TTCCAGCTCT |
|
9281 |
GTCTGTGTCC |
AGTCCCTGGG |
CTCTGGGCTT |
ATGTCAGAGA |
CTGGAAACTG |
TCATCAGTCT |
AATAGGAATA |
GCAACTCAAT |
|
9361 |
GTGATAGGAG |
TGTGGTGAAG |
GCCTTAGAGG |
CAACTCCAGG |
TCAAAGGTGG |
GGAACCAACA |
CCAAGATCCT |
GCCCAAAGGC |
|
9441 |
CCAGAGAGAC |
CGGGATCAGC |
GTCAGAGCCT |
GGAGTCAGGA |
TGGAGCAAGA |
GTCAGCCTTG |
GTTGTAGGAC |
AAGCAGGAAG |
|
9521 |
GCTGGGGCAC |
CAGGGCTGGG |
ACTAGGGTGT |
GGAAAGAGAG |
GCACCAAGGG |
CTTGAAACTT |
AAGGAGGTCA |
TGAACTTGCA |
|
9601 |
GAGGACATGT |
GAGTGGGAGA |
GGGATATTTC |
TTCCCTGTCT |
GGATGATCCC |
AACACTCATG |
GGCATATAGG |
GTCATGGTTG |
|
9681 |
CCTGTGTCTC |
TCACACCACG |
CCTTGGAACT |
GGCAAGTTCT |
GGGCTACCCT |
TTGAGACCTT |
CTTCTCTTCT |
ACACAGAGAA |
|
9761 |
ACCCCTGACA |
TTGACAAGCA |
GTATGTCTTA |
GTGACCATTT |
TCATAGTAGA |
ATTAGTTGCT |
GCCAATTTGT |
GTAATTTCAG |
|
9841 |
GGATACTGAG |
CAGACTCACA |
ACTTCCCAAC |
CAAGGAGGAA |
AACACTTCCT |
CTACCATCTT |
GTCCAAATTC |
AGGTCTTTTC |
|
9921 |
AGCATTAGCA |
ATTTATATAG |
GTGGTTCTGA |
AAGTGTTTTG |
AATCTTCTAG |
AGGTTCCATA |
AAATTGCAAA |
TGGCCTTGGT |
|
10001 |
GTGCACACAG |
GTGAAGCTGT |
CACTACTAAG |
GCATCAGTTA |
GGCTGGTGAC |
ACCTGCGAGT |
GAGACCTGGA |
AGGTTGGGGG |
|
10081 |
TGCAGGTGGT |
AGGTCAGGAG |
GCAGTAAGGT |
GGCTGGAGCG |
TCCATGTGGA |
GCCAGAATGA |
ATAGCCAGAT |
CTCCCACTCC |
|
10161 |
AGTCAGCTGG |
GGCAGTGGCC |
AGAACCAGTA |
GCCTTCAGCC |
AGGTGAAAGG |
GCATGAGGCA |
TTGGAAGGGA |
GCAGATGCCA |
|
10241 |
GGCAAAGTGA |
ACTCCTGTCT |
CTCCGGGGTT |
TTGTTTTTGT |
TTGAATTCAA |
AGTACTCAGA |
GATAGCCAGA |
CTGCAATGTC |
|
10321 |
TGAGGGCACC |
CTTACCTTTG |
ACACCACCTG |
CAAATTTAAG |
GGGATTTCTA |
AATCCATCCT |
TTGATTTTGT |
AATTCACTGG |
|
10401 |
AAGGACTCAC |
ATAACTCACT |
GAAAACTGCT |
ATTTCACAAT |
TGTGGTTGAT |
CACACGGAAA |
GAACACAGAT |
TAAAATCAGC |
|
10481 |
CTAAGAAAGA |
GACACACGGG |
GCAGAGTTTG |
GGAGGGTTTT |
AAGTGTGAAG |
CTTCATTGTC |
CTCAGGACGC |
TGTGTTCTCC |
|
10561 |
TGTGTGAATG |
TGGGACAAAA |
CACATGCGGT |
GTTGCCAACC |
AGGGAAGCTC |
ACCCAGTTAA |
GGAAAAATTC |
CTGTGAATCA |
|
10641 |
CATTAAACCA |
GAAATGAAGC |
CTTTTTTCAG |
GATTGTTGTT |
ACAGGGGAGG |
GAGACTGAGC |
CCAGCTCCAA |
ATATAGTAAA |
|
10721 |
GACAGAGGGG |
GAGTCACAGC |
CAACACCAGG |
GTGGGGGCGG |
GAGATGGAAC |
AGGACTGATA |
GGAGACACCA |
GAGTGGGGGG |
|
10801 |
TTCCTGCTAA |
ATTGGCCTAA |
CAGGATTCTC |
ACTAAAGGCA |
GGTCAGACAC |
TCACCCATCA |
ATGGTGGGGG |
TGAAGAGCAT |
|
10881 |
AATCAGATAG |
CAAAGCGTAA |
TCAGACAGCA |
AGGGGGGAAG |
ACCCTCCCTA |
AACTGACTTG |
GGGAGATTCT |
TGCTGAGCTG |
|
10961 |
GGTGGTGCAG |
GTCCAGCAAG |
CAGTGGGTGG |
CTGTGGAAGG |
CCAAGGTCGG |
CGCCTAGTGG |
AGAAGAGGCT |
CAGAAGAGCC |
|
11041 |
CAGCTGGAGT |
TGGTCAAGGA |
GAAAGTCCTT |
CTTTCTCAAC |
CCATGCCTTA |
GTGTCCAGAG |
TATCTGCTGG |
GGCTGGATCA |
|
11121 |
CAAGCTGCCC |
TCATGGCTGA |
CCTGGAGTCT |
CCAGCCCCTC |
CCTGAGGTCT |
AACCCCTTTA |
GTCCCCGGGT |
CCTCTGGGAT |
|
11201 |
CAGGAAAGAC |
ACCAAATAGC |
CCCAAACCCC |
ATCATCCATC |
AGATTCCTAT |
ACGGTCCCGT |
GGCCAAATCA |
CCAGGCAAAG |
|
11281 |
ACAGATGTTC |
CTACCAGGCA |
GGACATTCCA |
GGGGCCTGGA |
GATCACTTCC |
CAGGAGCTGA |
GGACAAAGGG |
AAGGCCTCTC |
|
11361 |
TTTGGGTAAA |
GTTCATGCTT |
CACTTTCCTG |
CCATCCTGGG |
AATAAGGTCT |
CTTTGTCTCA |
CTCTCACTGC |
TCTTTGTTCA |
|
11441 |
TCTGCAGAGT |
TTTCCCTCTC |
CAAACACTTT |
GGCAGTCACG |
GTGTTGACCT |
GCCCTTGAAT |
GAGGAGGCAT |
CTTTATCAAA |
|
11521 |
CACCTACCAT |
GAAAGAGCAT |
CTGAGATGCC |
TTTAAGATAT |
TTATTTCCAT |
ATGGAATAAA |
TATTGAGGAG |
TATCTATGAT |
|
11601 |
GAACAAAATG |
TGTTTGAGTT |
TGAAAGATAA |
TTAATTCCAT |
TTGTAAAATT |
TGTTTCTATT |
TGATCGATAG |
TGAAAGCTCT |
|
11681 |
GCAATTTACA |
CAGGATAGAG |
ATCACATGGA |
GCTCATTTCA |
CAGACAGGGA |
AACTGCATTT |
CTTTTTTTTT |
TTTTTTTTTT |
|
11761 |
TGAGTTGGAG |
TCTTGCTCTG |
TCGCCCAAGC |
TGGAGTGCAG |
TGGCGCGATC |
TCGGCTCACT |
GCAAGCTCTG |
CCTCCCGGTT |
|
11841 |
CAAGCAATTC |
TCCTGCCTCA |
GCCTCCTGAG |
TAGCTGGGAC |
TACAGGCGCC |
CACCACCACG |
CCCGGCTAAT |
TTTTTGAATT |
|
11921 |
TTTGGTAGAG |
ACAGGGTTTC |
ACCGTATTAG |
TCAGGATGGT |
CTCAATCTCC |
TGACCTTGTG |
ATCCACCCGC |
CTTGGCCTCC |
|
12001 |
CAAAGTGCTG |
GGATTACAGG |
TGTGAGCCAC |
CACACCGAGC |
CAAAACTGCA |
TTTCTTAATC |
CTTTAACCTT |
TCCTTGTGCA |
|
12081 |
GGAATGAGGC |
AGATGAGCTC |
CGTAAAGCTC |
TGGACAACCT |
TGCAAGACAA |
ATGATCATGA |
AAGACAAAAA |
CTGGCACGAT |
|
12161 |
AAAGGCCAGC |
AGTACAGAAA |
CTGGTTTCTG |
AAAGAGTTTC |
CTCGGTTGAA |
AAGTGAGCTT |
GAGGATAACA |
TAAGAAGGCT |
|
12241 |
CCGTGCCCTT |
GCAGATGGGG |
TTCAGAAGGT |
CCACAAAGGC |
ACCACCATCG |
CCAATGTGGT |
GTCTGGCTCT |
CTCAGCATTT |
|
12321 |
CCTCTGGCAT |
CCTGACCCTC |
GTCGGCATGG |
GTCTGGCACC |
CTTCACAGAG |
GGAGGCAGCC |
TTGTACTCTT |
GGAACCTGGG |
|
12401 |
ATGGAGTTGG |
GAATCACAGC |
CGCTTTGACC |
GGGATTACCA |
GCAGTACCAT |
GGACTACGGA |
AAGAAGTGGT |
GGACACAAGC |
|
12481 |
CCAAGCCCAC |
GACCTGGTCA |
TCAAAAGCCT |
TGACAAATTG |
AAGGAGGTGA |
GGGAGTTTTT |
GGGTGAGAAC |
ATATCCAACT |
|
12561 |
TTCTTTCCTT |
AGCTGGCAAT |
ACTTACCAAC |
TCACACGAGG |
CATTGGGAAG |
GACATCCGTG |
CCCTCAGACG |
AGCCAGAGCC |
|
12641 |
AATCTTCAGT |
CAGTACCGCA |
TGCCTCAGCC |
TCACGCCCCC |
GGGTCACTGA |
GCCAATCTCA |
GCTGAAAGCG |
GTGAACAGGT |
|
12721 |
GGAGAGGGTT |
AATGAACCCA |
GCATCCTGGA |
AATGAGCAGA |
GGAGTCAAGC |
TCACGGATGT |
GGCCCCTGTA |
AGCTTCTTTC |
|
12801 |
TTGTGCTGGA |
TGTAGTCTAC |
CTCGTGTACG |
AATCAAAGCA |
CTTACATGAG |
GGGGCAAAGT |
CAGAGACAGC |
TGAGGAGCTG |
|
12881 |
AAGAAGGTGG |
CTCAGGAGCT |
GGAGGAGAAG |
CTAAACATTC |
TCAACAATAA |
TTATAAGATT |
CTGCAGGCGG |
ACCAAGAACT |
|
12961 |
GTGACCACAG |
GGCAGGGCAG |
CCACCAGGAG |
AGATATGCCT |
GGCAGGGGCC |
AGGACAAAAT |
GCAAACTTTT |
TTTTTTTTCT |
|
13041 |
GAGACAGAGT |
CTTGCTCTGT |
CGCCAAGTTG |
GAGTGCAATG |
GTGCGATCTC |
AGCTCACTGC |
AAGCTCTGCC |
TCCCGTGTTC |
|
13121 |
AAGCGATTCT |
CCTGCCTTGG |
CCTCCCAAGT |
AGCTGGGACT |
ACAGGCGCCT |
ACCACCATGC |
CCAGCTAATT |
TTTGTATTTT |
|
13201 |
TAATAGAGAT |
GGGGTTTCAC |
CATGTTGGCC |
AGGATGGTCT |
CGATCTCCTG |
ACCTCTTGAT |
CTGCCCACCT |
TGGCCTCCCA |
|
13281 |
AAGTGCTGGG |
ATTACAGGCG |
TGAGCCATCG |
CTTTTGACCC |
AAATGCAAAC |
ATTTTATTAG |
GGGGATAAAG |
AGGGTGAGGT |
|
13361 |
AAAGTTTATG |
GAACTGAGTG |
TTAGGGACTT |
TGGCATTTCC |
ATAGCTGAGC |
ACAGCAGGGG |
AGGGGTTAAT |
GCAGATGGCA |
|
13441 |
GTGCAGCAAG |
GAGAAGGCAG |
GAACATTGGA |
GCCTGCAATA |
AGGGAAAAAT |
GGGAACTGGA |
GAGTGTGGGG |
AATGGGAAGA |
|
13521 |
AGCAGTTTAC |
TTTAGACTAA |
AGAATATATT |
GGGGGGCCGG |
GTGTAGTGGC |
TCATGCCTGT |
AATCCGAGCA |
CTTTGGGAGG |
|
13601 |
CCAAGGCGGG |
CGGATCACGA |
GGTCAGGAGA |
TCGAGACCAT |
CCTGGCTAAC |
ACAGTGAAAC |
CCCGTCTCTA |
CTAAAAATAC |
|
13681 |
AAAAAATTAG |
CCGGGCATGG |
TGGCGGGCGC |
CTGTAGTTCC |
AGCTAACTGG |
GCGGCTGAGG |
CAGGAGAATG |
GCGTGAACCT |
|
13761 |
GGGAGGTGGA |
GCTTGCAGTG |
AGCCGAGATA |
TCGCCACTGC |
ACTCCAGCCT |
GGGTGACAGA |
GCGAGACTCC |
ATCTCAAAAA |
|
13841 |
AAAAAAAAAA |
AAGAATATAT |
TGACGGAAGA |
ATAGAGAGGA |
GGCTTGAAGG |
AACCAGCAAT |
GAGAAGGCCA |
GGAAAAGAAA |
|
13921 |
GAGCTGAAAA |
TGGAGAAAGC |
CCAAGAGTTA |
GAACAGTTGG |
ATACAGGAGA |
AGAAACAGCG |
GCTCCACTAC |
AGACCCAGCC |
|
14001 |
CCAGGTTCAA |
TGTCCTCCGA |
AGAATGAAGT |
CTTTCCCTGG |
TGATGGTCCC |
CTGCCCTGTC |
TTTCCAGCAT |
CCACTCTCCC |
|
14081 |
TTGTCCTCCT |
GGGGGCATAT |
CTCAGTCAGG |
CAGCGGCTTC |
CTGATGATGG |
TCATTGGGGT |
GGTTGTCATG |
TGATGGGTCC |
|
14161 |
CCTCCAGGTT |
ACTAAAGGGT |
GCATGTCCCC |
TGCTTGAACA |
CTGAAGGGCA |
GGTGGTGGGC |
CATGGCCATG |
GTCCCCAGCT |
|
14241 |
GAGGAGCAGG |
TGTCCCTGAG |
AACCCAAACT |
TCCCAGAGAG |
TATGTGAGAA |
CCAACCAATG |
AAAACAGTCC |
CATCGCTCTT |
|
14321 |
ACCCGGTAAG |
TAAACAGTCA |
GAAAATTAGC |
ATGAAAGCAG |
TTTAGCATTG |
GGAGGAAGCT |
CAGATCTCTA |
GAGCTGTCTT |
|
14401 |
GTCGCCGCCC |
AGGATTGACC |
TGTGTGTAAG |
TCCCAATAAA |
CTCACCTACT |
CATCAAGCTG |
G |
|
|
|
|
|
|
|
|
|
|
|
|
>ref|Gene_ID:8542|APOL1|NC_000022.10:36649116...36663576 (+)
TGACTTTCACTTTCCCTTTCGAATTCCTCGGTATATCTTGGGGACTGGAGGACCTGTCTGGTTATTATACAGACGCATAA
CTGGAGGTGGGATCCACACAGCTCAGAACAGCTGGATCTTGCTCAGTCTCTGCCAGGGGAAGATTCCTTGGTAAGTTGGG
GACAGTTGACCTGCCTCCATCTTATTCTCACAGCTTTTGTAGATAAGCTGGGAGAGGTTAGGTGACTGGTTCAGATAGAC
AGGAAAGTAGCGGCAAAGCCTGGATTTGCACCCAGGCTTGAGTCTGATTGCTTCCCCTCTCCTGCTGGGCTCTTAAACTA
TAGAGGGTTGGGGAAACAGCTCAGATGGGTTCACAAAGCTCCCTGGGCTCAGCCCTGGTTTTGACTGCTGAGACACGACT
GAGTGAACCCAGAAGGAAGGTTTGTGTTGGGGGTGCCCATCTCTTTGGGAAATTTGAAGGAACCAAAGAAGGTGGAGGAG
AGGAGGTGACCCAGATCCCAGCCTGTTCTTATGGCCAGGCCACACCAAGGCTGGCCCCAGGGTGCTGCTGCTGAGGCCCA
ATGGGGGCAACAGAATTTTTTTTCAGGTACAAGGAGTTCAGAGGTCATCTCACCCACCCTGAGTCTGAGCACCAACTTGT
GCCAGGCCCTGTGGGGAAACTGAGGCCCTGGGAGCGGAATGACTTGCCCAGGGTCCCGTGTCAGGAGGCTGAGCAGGTAG
ATCATAGGACTCCACGTCTCTGGCCCTCACCTCTGTCCCTCTGTTCAGACTTCTGGGGTGATGGAGAAGAAACAGGCTGT
GCTGTGTCCCTAATGGGAAACGTGGCTGAGACAGGGGAGTGAGAAGGGTGCGTTGCAGAATGGTGCCTGTGGCATGATGC
CAGCTTTGCAATCATGAGATTCAAAAGCCACACTGTGGAATTGTGAGTATAACTACAGGAGTGAGAGCTTAGATCTCTGT
GTTCATAGAAGGAGAATCAAACCTGGAAACTTTTGGATTATTAAAATCAAACATTTTTGCTTCAATATTAGAGTCACAAG
GGCAGATGTTGGCCTCCCCTCTGCCCTCCAAGAGCTGTGTGACTCTGGGAAATTCACCTCCCCTCCCAGCCTGAGTATTT
TCCCCTGTAAAAAACCTGATAGAGCTGCCAAAAGTCCATGAAATCAGGGGGGTAATTTCTGTGAAATCTGAGTCATGGTC
TTATTTGTTCTTCACCAAAAAGAGATGATGAAGCCTGTAACCCCAGTGCTGTGGGAGGCAGAGGCGGGAGGATGACTTGA
GGCCAGGAGTTCAAGACAGCCTGGGAAACACAGGAGATGCTGTCTCTATGAAATCAAAAATTAACAAATTAGCCCAGCAT
GGTAGTGTGTACCTGTAGTCCCAGCTACTCAGAAGGTTGAAGGAGGCGGATCACTTGAGCCCAACAGATCTAGGCTGCAA
TGAGCTAGGATGGTGTCAAAGCCCTGCAGCCTGGGTGACAGAGCAAAACTGTTTATTAAAAACTAAACGAAAGGCCGGGC
GCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCAAGACAGGTGGTCACGAGGTCAGGATATCGAGACCATCCT
GGCTAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAAAATTAGCCGGGTGTCGTGGCGGGCACCTGTAGTCCCAG
CTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACCCGGGAGGCAGAGCTTGTAGCGAGCCTAGATCGCCCCACTGCAC
TCCAGCCTGGGTGATAGAGCGAGACTCCATTTCAAAAAAAAAATGAAATGAAAATGGTGATTTCTCAGGAGGAGCACACT
GTCTCAACCCCTCTTTTCCTGCTCAAGGAGGAGGCCCTGCAGCGACATGGAGGGAGCTGCTTTGCTGAGAGTCTCTGTCC
TCTGCATCTGGTGAGCTTGGCTCAGAGCCCTGAGGCGGGAGGGAGGGCTCCCTGTCTGGGCTGCACAATTGGACTGGGCT
TGGGCTGGGCCAGGGCCATCTGGGCTTCTTCTAGGAACCAAAGTCACTTCCCGGAATTGACCAACCGGCAGACTCGCCCA
GGGAGGACCCGCTGTATCCTAGTTGAGGCTAACGGTCAATATCCGGCCTCAATATTCAGCAGAGGCTCCAGGTCAGGGTC
TGAGCCAGGCCAACAATGACCAAGGAGGATGGGATCCAGGGTGCAGCTCCTCACAAGTGTCGGGGGAATCCGAGGCACCA
GCTCTCTCTACCCTCCTGCTCCTCTGCTCTCTCCTGGTCCTCCTGTGTCCTCATGGCTCATGAGATGGTGTTGAGATGGC
TCCCCTGGCCTAGGGGATCACACAGTGAACAAAGCAGGAAGAAGGCGAAGGGATGCCCCTCTCCTGTCACCCTTGTCCCT
TACAGCAAGAAGGGCCCAGACGCCCCTCTGCATACTCCCCTGGTGAACTGCTGCCCAGGACTGGGTCCCCCTTTTACCCT
TGCTGCATGGAGTCCCCAGAAGACAAACATCTGTGTGTCTGAACCCTGAGACAAAGGCAGGAAAGGGAAAGAGGGAGGCG
AGTGGCTTTTGAGGAGGGGGCTTTAGTATGAGAGCTGGAGGATGGAACCCCATCAGGGGGCCCGGGAACCACTGAGCTGT
TAAAATAAAGTCTGCAAACAAAGACCAGCTGCTGGAAGTGGGTGTGCCAGGGAGTGCGCAGAGACACACGGTGAGAAAAG
AACAATGGTAATGCTTGGAGCCGCCCCTAACTGGGATGGGCCTGAAATGGTATTGTTATTATTTATAGTATCATTATTAG
TCATTTTCATCTTATTTGTACCCTCCCTCTATCTCTCCTCTCCACCTTTTCCTAACATTCTATCACCAGTTTTATGTCTT
CCATTAGCAACTTTGTAGCTGTAAATAATTTACTTACAACTTTCATATACCCTCAGTTGTACCCAGTATTTCTTAACTTC
CCTCTTTAAAAAAATGATAATATTAATCCTCCTTCTCCTTCGTTCAGTGCTTCACATCCCAACTGCTACCTTTGTGCTTT
AAATTTTGTACTAATTGGTGTTGATAACAAGTATATTTAGTTCTCATATTTATATGTTGTGTATATGTTTTGGTTTTTTT
TTGTCTTAAACAAGAGACTACTGAGAGCCAGTAAGACTGAAAGAAAGGGCATCTTCATATACTGCTAGTTTGAGTGTGAA
TTGGTACAATTTGCCTGCAGTGTGGCTCTAGGTATAAAGCCTTTTGAGTTGTTGATAGCCTCTGACCTGCTCATTCTACT
CCTACAAATATCTTAAGGAAATAATCTCAAATGTGGGCAAAGTTTTATGCGAAGAAGGATGTTCTTTGTAGCATAATTTA
TATGAGGAATTAGAAACACCCTGAGGTCCATCAGCTAGGGAAAGACAGCAGAGGGGACAGGGCAGCACCAGGAGGGCTTG
GCAGCCACAGCAGGGGCTGGGCTGGCATCTGGCAAGATCCAGGTCTTTGTGGGACAAAGAATCTTAGAGAAGCAACGGGG
ACACAGGCTGTCCAGTGCAGCACCAGTGAATTCACCAAGATGAAGAGTTGAGCACAGAGTGTGAGACAAGGATTTGCAAT
GAGGAGTCATTTACCATGAGCGTGTATACATGACTCAATATTGTATATTTAAGGGAGTAGAGCACAGTCATTGAAAACAT
GGGGTTGAAGCAGAAGTCCTGGCTCTAGCACTATTGTAAAAACACTGGCAAGTTCCCTAACTTTTGTGGATTCCTCTGTG
TTTGAATGGGAAAGTGGTACCCATCTCCTGGCCTGTGTGTGATCATCGAATGAGACACATGTAAGAGGCTCTGCACATCG
CAGACATGCAATACACACTGGCTATCACCAGCTAGTTATCACACATGCTCCCAGGCCCTGGTCATTGTCAGAACCTTCCT
CCCCATCTCTATTTCTGTGTATAGACTCTGTAGTTTCTGTAATGATCAGATGGCTGCCCGTCCTCTGATTATCTTCTCCT
CATACCCCAACAGGATGAGTGCACTTTTCCTTGGTGTGGGAGTGAGGGCAGAGGAAGCTGGAGCGAGGTGAGTGTCTGCA
AATAGCAGATGATGGGGGCTCAGTGATAGACAAACAATCTGGTTTAGGTTGGTCTTGGTGTTTGCTTCCACCCCAGAGAG
ATTTGCAGAGCCCCGGCTGCTCAAGCAAGCCTCCCTCTGTCCACTGGTGGCTCACATTTGATCCCACAATTTGTTTTCTC
CTCCTCAAGGGTGCAACAAAACGTTCCAAGTGGGACAGATACTGGAGATCCTCAAAGTAAGCCCCTCGGTGACTGGGCTG
CTGGCACCATGGACCCAGGTAGGCTCACCTCCTCTTCCCTGCTGGTTCCTACTCGCACTTAGAATGGAGGGTGGCACCTC
CACAGCTGAGTGAGCCCCAGAAGAACCCGGATGGACTAGGAGGCCAATGAGTCTGCCCAAAGCAGCAGAAGAGGTCACGT
GGAGTCCCCCGACCCAGGGGTCTGGGGGTCATCTGCATCCTGACCTCTCCTTAGGGTGACACGGCCCAGGTGCCCACTTC
CTCCCTACCCTGGCACCTAGCAAATGACTCAAGTGGGGCAGGACATCCTTGGGGAAGTGGAATCAGCGGGGGGGGGGGGG
AGTGTGGGGAGAGCAGGGTCCAGGAGGAGAGGAGGGCTGGGAGAGGAGGTTGACCAGCAGCCCCGACCTGTCACCTCCCG
CTCTGCTCCAAGCTGACCCTGGGGTGTTTCCACCTGAGGCTGGTCCCCTCCCTCCAGCTCTTGCCCTGCCCTAGCCCCTT
TGCTCTGAGTGGCCCTGTGGGAATGTATCGGGCCTGATTCAGCTTCCAGCTTAACTGGACCCCGGTCTGTCCTTTGCCAC
ATCCCCTCTGTGTGACCTGGCGCTCCTTACCTCCCTTCTCCTGTACCATGAGAATAATATTTCCCCATGTTGTCTTGAGG
ATCAAATATAACACGGCTACCTGGCCTGGCCAGTGCCTGCCACACAATAGGGCCTCCCTAAGGGCTGGTTCCCATCCCCT
CTACTGGTCCCCTGTTGATTCCAGGTGGAAGCCACCCCGTCCCCCCCCAGCTGTGTTAGGGCACCCGCCCTGCCCTGCCC
ATCACAAGCACCTGCTTACCAGGGATGACTGCCTCAGGCAGGGGCTGAGTTCAGTCATCTAAAATACCCCCGGTCAAAGA
AAAATCTGAGGCCCAATAGAATTTTAAAGAGTTAATTGAGTAAGAAAGGATTGCTGAATTGGGAAACAGCAAACTGGAGG
AGGCTTCGTGCTATGGTGAAAAAGTGTCGGAGACAAGGTTTATCGGGTGAATATGAAACTGCAGTAAGGACATTATTTGA
TTGGTTGCACTTACAAAACTGCCTGTTTGGGTTTACCTTGTTGGAAAATCCCTGGTCACGTTGGTGCCAGTGTGAGTTTA
GGGAGGTCTCCGAATACAGGTGAGACCGGAACTTAGCCTTGCCCAGGTTTTTGATGCTGAAGAGAGAAAAAAGTCAAAGC
AAAAGCAAATCAGCTTTTAGTGCAAAACAGAAGTGCAGGCTCAGGGGTGGGAGTGCAGGCGGACTCAGAAGAGCCAGTCG
GGCCCAGTGGAGTTTGGGGTTCTTGTCTTTGCTGGTTTATTAAATTAAGGTGTGGAGTAAGCATAAGGATTTCTGGGAAG
AGGTGGGGATTTCTTGGAATTGGGAGGGCAATGCAGTTTTGTACCAAACATGGGCATACATGGAACGGCTGTGGTGCGGG
TGGGTGTGGGGTTTAGTGAGACAAGGAGGGTATGATTGAGTGTGAGGCAAAACGTGGGTCAGACCCAGCGCCGAGTTGGA
TCTCACTGGTCTTAGCTGAATTGGCCACTTCCTGTTTGTCAGGATCCTGTGGGCCCATCCCCTCCCCCTGTCCCTACAGG
TGGTTTCAGCAACTCCTTCTGTGTCTGTCATGTGAACCTGCTGCCTGGAGTTCTTGTTTCTTCTGTGACCTCCCAGTATC
CACATCTCAGCATGGCCCTCTGTCAGCTGGCTTTAAGTTTTGTTTGTATCTAACAGAAGTACCCATCTGATATGACCCCA
GTTGAGTTTCCCATAGCTTGCAGTTTCAGGGGGTTACAGCTGTTCTAAAGGCCTCGTAGGTATTGCCTGTCCAGGAATGT
TTCAGGGCTGGTTTTTGTTTTAATTTTGCTTTTATATCCACCAGCCCCACCACATCAAGAAATACACAGATTTAGTGCCA
GAGGTTCCTTCCATCCAAACCTGGGTTTCCTTCCTCCTTTTGGTGAAGAAGGAAAAAGAAAAAACAAGACAATCGCTCGC
CCAGCCAAGTCAGCATTGCGTTCATTTCCCTAAGCCCCATTTCCTCAGGAGGGCTTCCTCCCCTTACAGAGTTGCCACGG
CAACCAAGTCAGCTCTGCTCAGGAGCCGCCCTGGACAGCAAACTGGGCTGTGCTGAGTCCTGTCCAAGACGAGGGGAGGG
CAGGGAAGATTAGAAGCCGAGAGCACTCAGCCGACCCCGGAATCCTTACGAAGGGCTGGGCTGGGGGACTGAGGAAAAAC
TCTCCCCCCAAAACAAGATGATCTGTGGTTTAATAACAGGCCCAGCTGGGTCCAGAGGTGACAGTGGAGAGCCGTGTACC
CTGAGACCAGCCTGCAGAGGACAGAGGCAACATGGAGGTGCCTCAAGGATCAGTGCTGAGGGTCCCGCCCCCATGCCCCG
TCGAAGAACCCCCTCCACTGCCCATCTGAGAGTGCCCAAGACCAGCAGGAGGAATCTCCTTTGCATGGTAGTTGTACTCA
ATGCTGTGGAGTTTGAGACATTATTTTTAAACTTTAAATAGCCCCACAGGTAAGCTATAAGGGAGAATGCAGAGACCACA
GGCATTTTCAAAACATAAGGAGTTTTAATGTTAAGGAGTTTAAGGAGAATGTCAAAGAAACATTGGCCTTGGAGTCAAAT
CCTGAGCTTCCTGCTTGATGGTTTTGGGCGGTGACTCTCGCTGTCTGGATTTTACTTTCTTCATCTGTGAATTAAGAATG
AGGTGGCCGGGCACTGTGGCTCACGCCTGTAATCCCAACATTTGGGAGGCCGAGGCGGGCAGATCACAAGGTCAGGAGAT
CGAGACGATCCTGTCTAACACGATGAAACCCTGTCTCTACTAAAAATACAAAAAAAATTACCAGGCCTGGTGGCAGGCGC
CTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATGGCATGAACCCAGGAGGCAGAGCTTGCAGTGAGCCAAGATC
GCACCACTGCACTCCAGCCTGGGTGAGAGAGCAAGACTCCATCCCCCCAAAAAAAAGAATGAGGTCTCTTGTGTGTGCAC
GGCAAGAAACAATTTTACATCATGCCTCAGTGCACACACAAATACATACTGGTCCCCAGTTCCTTATCTGCAATTCCATA
ATTCCCAGATCCCTGCAAACCACACGTTTTGGTGGCAGCTGACTTCAGGAGTAATCCTGCTCTGTACTGACTTGAGTTCT
TTGTAGACCTACCATTATTTTTTACATTTAATGTGAATATTTGCTTGTTTCACTGTTGAAACATGTGTGGGTGTGATTAC
AGGGAGCAGTCCAGCCTCTGCTGGGAATGGTCAGGAATATACCATATGCACCCCGTGTCCTTTCTAAAATAGTGGAAATT
CTGAATGCCTAAACACATCTGGATTCCAGGAATTTACATTAAGGGATATATATTTGAAATAACCCACAAAAACAATACTC
ACCCCTGCTACGCTTGGTACACTCTGATATTTTCAAATTGATTTTCTTTTTAAAATGCTGCTTTTGAACCAATAATTTCA
TAACCCAATGATGTGTTGATATTCACATTTTGAAGACACTGGTATAAAGTGTTTGACCCAACAGGCATGTGGCAGATGGA
AGTGATCACTGGGATGTTTCCACTTCCTTGGCCTGGAAGGCTCACTTCATGTTGGTGCTGAGCTGAAAAGGATTCATTCC
TCTCCAAAGCACCATGGCACTCCCCTGGTGTTTCAATGTTCTCAGGCTGCCATAGTAAAATATCACAGGCTGGGTGACTT
CAACATCTGGCTTTTATTTTCTCACAGATCCAGAGGCAAGAAGTCCAAGGTGAAGGTGCCAAAAGGGTTGGAGTCTGGGG
AGGACTCTCTTGCTGGCTTATGGAAGCTGCCTTTGCACTGTGTGCTCACACAGTCTTCTTGTGTCCCTTTCTGTTCTTAC
AATAGGACACTAGCCCTCTAATAGAATTAGAGCCCTACCCTTGTGATCTCATTCAGTCTTAATTGCTTCCTTAAAGGCCA
GATCTCCAAATGTAGTCACCTGAGTTTAAAGCTTCAGCATATGAATTTTGGGGGCACACAATTCCCTCTATAGCACTAAT
GACTCCATAAAACAAGTCCCACATCACAGCTGTCCAGGAAAATTAACATGTAGTCATCTCTTATGCAATGGCTGTTATGC
ACTCCCACACTTTCCTCCAACCTTATCCTTTCTTCTTTCCAACTAGAGAGCAGTATCTTTATTGAGGATGCCATTAAGTA
TTTCAAGGAAAAAGTGAGCACACAGAATCTGCTACTCCTGCTGACTGATAATGAGGCCTGGAACGGATTCGTGGCTGCTG
CTGAACTGCCCAGGTAAGCTCCATGGGGTTACCTCCATTGGGCACTCCGGCGATGCCACCCAGCTCTCCCCTGGGCTAGT
TTTCCCTGACAGGCACACCTCCTCCAGGCAGCCCCCTCTGCTGGGCTTGAGGATGACCTTCTTGGCACTCCAGGAAGAAT
ATTTCCTCCATGTCCTTCGCTGGCAGTGAGTAGCCTCAGGCTGAGGGGATAGGAAGCCCACAGGAACAGGGTCATTTCTG
CCATCTGCTGGTGATGGGAACTTTGCCAGTTACTTTCTCACTTTCAGCCTTTCTTCATCAATGGAGTTTTATTGTGAGAA
AAATGAGATCGTGCATGTAAAGTGCTTAGCATAATGACTGACACACAGTAGGTGCACAGTTAACGTTAACATCTTACAAG
CTTGGTGGAAACAGAACCAGGGTTAAGGATCTTCTTCTTGAAGATGGGAGCCCAGCAGGACTTGACCTTTGGGACAAGTC
AGAAAAATCCTGACCTAACCAATGTGTGTTCCTGGGGATGCTGGCTGGAGCCCTTTTTCTCATCTGAGGAATTCCATAAA
CACGGCAGGACCCTTCTGCTGGTCCAGGATGCCGAGAGGCTGGAGTGGAGTTGCACAGCGCTGGGTCTCTTTCCAGCTCT
GTCTGTGTCCAGTCCCTGGGCTCTGGGCTTATGTCAGAGACTGGAAACTGTCATCAGTCTAATAGGAATAGCAACTCAAT
GTGATAGGAGTGTGGTGAAGGCCTTAGAGGCAACTCCAGGTCAAAGGTGGGGAACCAACACCAAGATCCTGCCCAAAGGC
CCAGAGAGACCGGGATCAGCGTCAGAGCCTGGAGTCAGGATGGAGCAAGAGTCAGCCTTGGTTGTAGGACAAGCAGGAAG
GCTGGGGCACCAGGGCTGGGACTAGGGTGTGGAAAGAGAGGCACCAAGGGCTTGAAACTTAAGGAGGTCATGAACTTGCA
GAGGACATGTGAGTGGGAGAGGGATATTTCTTCCCTGTCTGGATGATCCCAACACTCATGGGCATATAGGGTCATGGTTG
CCTGTGTCTCTCACACCACGCCTTGGAACTGGCAAGTTCTGGGCTACCCTTTGAGACCTTCTTCTCTTCTACACAGAGAA
ACCCCTGACATTGACAAGCAGTATGTCTTAGTGACCATTTTCATAGTAGAATTAGTTGCTGCCAATTTGTGTAATTTCAG
GGATACTGAGCAGACTCACAACTTCCCAACCAAGGAGGAAAACACTTCCTCTACCATCTTGTCCAAATTCAGGTCTTTTC
AGCATTAGCAATTTATATAGGTGGTTCTGAAAGTGTTTTGAATCTTCTAGAGGTTCCATAAAATTGCAAATGGCCTTGGT
GTGCACACAGGTGAAGCTGTCACTACTAAGGCATCAGTTAGGCTGGTGACACCTGCGAGTGAGACCTGGAAGGTTGGGGG
TGCAGGTGGTAGGTCAGGAGGCAGTAAGGTGGCTGGAGCGTCCATGTGGAGCCAGAATGAATAGCCAGATCTCCCACTCC
AGTCAGCTGGGGCAGTGGCCAGAACCAGTAGCCTTCAGCCAGGTGAAAGGGCATGAGGCATTGGAAGGGAGCAGATGCCA
GGCAAAGTGAACTCCTGTCTCTCCGGGGTTTTGTTTTTGTTTGAATTCAAAGTACTCAGAGATAGCCAGACTGCAATGTC
TGAGGGCACCCTTACCTTTGACACCACCTGCAAATTTAAGGGGATTTCTAAATCCATCCTTTGATTTTGTAATTCACTGG
AAGGACTCACATAACTCACTGAAAACTGCTATTTCACAATTGTGGTTGATCACACGGAAAGAACACAGATTAAAATCAGC
CTAAGAAAGAGACACACGGGGCAGAGTTTGGGAGGGTTTTAAGTGTGAAGCTTCATTGTCCTCAGGACGCTGTGTTCTCC
TGTGTGAATGTGGGACAAAACACATGCGGTGTTGCCAACCAGGGAAGCTCACCCAGTTAAGGAAAAATTCCTGTGAATCA
CATTAAACCAGAAATGAAGCCTTTTTTCAGGATTGTTGTTACAGGGGAGGGAGACTGAGCCCAGCTCCAAATATAGTAAA
GACAGAGGGGGAGTCACAGCCAACACCAGGGTGGGGGCGGGAGATGGAACAGGACTGATAGGAGACACCAGAGTGGGGGG
TTCCTGCTAAATTGGCCTAACAGGATTCTCACTAAAGGCAGGTCAGACACTCACCCATCAATGGTGGGGGTGAAGAGCAT
AATCAGATAGCAAAGCGTAATCAGACAGCAAGGGGGGAAGACCCTCCCTAAACTGACTTGGGGAGATTCTTGCTGAGCTG
GGTGGTGCAGGTCCAGCAAGCAGTGGGTGGCTGTGGAAGGCCAAGGTCGGCGCCTAGTGGAGAAGAGGCTCAGAAGAGCC
CAGCTGGAGTTGGTCAAGGAGAAAGTCCTTCTTTCTCAACCCATGCCTTAGTGTCCAGAGTATCTGCTGGGGCTGGATCA
CAAGCTGCCCTCATGGCTGACCTGGAGTCTCCAGCCCCTCCCTGAGGTCTAACCCCTTTAGTCCCCGGGTCCTCTGGGAT
CAGGAAAGACACCAAATAGCCCCAAACCCCATCATCCATCAGATTCCTATACGGTCCCGTGGCCAAATCACCAGGCAAAG
ACAGATGTTCCTACCAGGCAGGACATTCCAGGGGCCTGGAGATCACTTCCCAGGAGCTGAGGACAAAGGGAAGGCCTCTC
TTTGGGTAAAGTTCATGCTTCACTTTCCTGCCATCCTGGGAATAAGGTCTCTTTGTCTCACTCTCACTGCTCTTTGTTCA
TCTGCAGAGTTTTCCCTCTCCAAACACTTTGGCAGTCACGGTGTTGACCTGCCCTTGAATGAGGAGGCATCTTTATCAAA
CACCTACCATGAAAGAGCATCTGAGATGCCTTTAAGATATTTATTTCCATATGGAATAAATATTGAGGAGTATCTATGAT
GAACAAAATGTGTTTGAGTTTGAAAGATAATTAATTCCATTTGTAAAATTTGTTTCTATTTGATCGATAGTGAAAGCTCT
GCAATTTACACAGGATAGAGATCACATGGAGCTCATTTCACAGACAGGGAAACTGCATTTCTTTTTTTTTTTTTTTTTTT
TGAGTTGGAGTCTTGCTCTGTCGCCCAAGCTGGAGTGCAGTGGCGCGATCTCGGCTCACTGCAAGCTCTGCCTCCCGGTT
CAAGCAATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCGCCCACCACCACGCCCGGCTAATTTTTTGAATT
TTTGGTAGAGACAGGGTTTCACCGTATTAGTCAGGATGGTCTCAATCTCCTGACCTTGTGATCCACCCGCCTTGGCCTCC
CAAAGTGCTGGGATTACAGGTGTGAGCCACCACACCGAGCCAAAACTGCATTTCTTAATCCTTTAACCTTTCCTTGTGCA
GGAATGAGGCAGATGAGCTCCGTAAAGCTCTGGACAACCTTGCAAGACAAATGATCATGAAAGACAAAAACTGGCACGAT
AAAGGCCAGCAGTACAGAAACTGGTTTCTGAAAGAGTTTCCTCGGTTGAAAAGTGAGCTTGAGGATAACATAAGAAGGCT
CCGTGCCCTTGCAGATGGGGTTCAGAAGGTCCACAAAGGCACCACCATCGCCAATGTGGTGTCTGGCTCTCTCAGCATTT
CCTCTGGCATCCTGACCCTCGTCGGCATGGGTCTGGCACCCTTCACAGAGGGAGGCAGCCTTGTACTCTTGGAACCTGGG
ATGGAGTTGGGAATCACAGCCGCTTTGACCGGGATTACCAGCAGTACCATGGACTACGGAAAGAAGTGGTGGACACAAGC
CCAAGCCCACGACCTGGTCATCAAAAGCCTTGACAAATTGAAGGAGGTGAGGGAGTTTTTGGGTGAGAACATATCCAACT
TTCTTTCCTTAGCTGGCAATACTTACCAACTCACACGAGGCATTGGGAAGGACATCCGTGCCCTCAGACGAGCCAGAGCC
AATCTTCAGTCAGTACCGCATGCCTCAGCCTCACGCCCCCGGGTCACTGAGCCAATCTCAGCTGAAAGCGGTGAACAGGT
GGAGAGGGTTAATGAACCCAGCATCCTGGAAATGAGCAGAGGAGTCAAGCTCACGGATGTGGCCCCTGTAAGCTTCTTTC
TTGTGCTGGATGTAGTCTACCTCGTGTACGAATCAAAGCACTTACATGAGGGGGCAAAGTCAGAGACAGCTGAGGAGCTG
AAGAAGGTGGCTCAGGAGCTGGAGGAGAAGCTAAACATTCTCAACAATAATTATAAGATTCTGCAGGCGGACCAAGAACT
GTGACCACAGGGCAGGGCAGCCACCAGGAGAGATATGCCTGGCAGGGGCCAGGACAAAATGCAAACTTTTTTTTTTTTCT
GAGACAGAGTCTTGCTCTGTCGCCAAGTTGGAGTGCAATGGTGCGATCTCAGCTCACTGCAAGCTCTGCCTCCCGTGTTC
AAGCGATTCTCCTGCCTTGGCCTCCCAAGTAGCTGGGACTACAGGCGCCTACCACCATGCCCAGCTAATTTTTGTATTTT
TAATAGAGATGGGGTTTCACCATGTTGGCCAGGATGGTCTCGATCTCCTGACCTCTTGATCTGCCCACCTTGGCCTCCCA
AAGTGCTGGGATTACAGGCGTGAGCCATCGCTTTTGACCCAAATGCAAACATTTTATTAGGGGGATAAAGAGGGTGAGGT
AAAGTTTATGGAACTGAGTGTTAGGGACTTTGGCATTTCCATAGCTGAGCACAGCAGGGGAGGGGTTAATGCAGATGGCA
GTGCAGCAAGGAGAAGGCAGGAACATTGGAGCCTGCAATAAGGGAAAAATGGGAACTGGAGAGTGTGGGGAATGGGAAGA
AGCAGTTTACTTTAGACTAAAGAATATATTGGGGGGCCGGGTGTAGTGGCTCATGCCTGTAATCCGAGCACTTTGGGAGG
CCAAGGCGGGCGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACACAGTGAAACCCCGTCTCTACTAAAAATAC
AAAAAATTAGCCGGGCATGGTGGCGGGCGCCTGTAGTTCCAGCTAACTGGGCGGCTGAGGCAGGAGAATGGCGTGAACCT
GGGAGGTGGAGCTTGCAGTGAGCCGAGATATCGCCACTGCACTCCAGCCTGGGTGACAGAGCGAGACTCCATCTCAAAAA
AAAAAAAAAAAAGAATATATTGACGGAAGAATAGAGAGGAGGCTTGAAGGAACCAGCAATGAGAAGGCCAGGAAAAGAAA
GAGCTGAAAATGGAGAAAGCCCAAGAGTTAGAACAGTTGGATACAGGAGAAGAAACAGCGGCTCCACTACAGACCCAGCC
CCAGGTTCAATGTCCTCCGAAGAATGAAGTCTTTCCCTGGTGATGGTCCCCTGCCCTGTCTTTCCAGCATCCACTCTCCC
TTGTCCTCCTGGGGGCATATCTCAGTCAGGCAGCGGCTTCCTGATGATGGTCATTGGGGTGGTTGTCATGTGATGGGTCC
CCTCCAGGTTACTAAAGGGTGCATGTCCCCTGCTTGAACACTGAAGGGCAGGTGGTGGGCCATGGCCATGGTCCCCAGCT
GAGGAGCAGGTGTCCCTGAGAACCCAAACTTCCCAGAGAGTATGTGAGAACCAACCAATGAAAACAGTCCCATCGCTCTT
ACCCGGTAAGTAAACAGTCAGAAAATTAGCATGAAAGCAGTTTAGCATTGGGAGGAAGCTCAGATCTCTAGAGCTGTCTT
GTCGCCGCCCAGGATTGACCTGTGTGTAAGTCCCAATAAACTCACCTACTCATCAAGCTGG
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Primary source |
RefSeq : NM_003661.3 (GI:211938437)
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Name |
Apolipoprotein L, 1 (APOL1), transcript variant 1
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Type of transcript |
mRNA
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Organism |
Homo sapiens
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Length |
2885 nt
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Map |
22q13.1
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Location |
Chromosome 22 (NC_000022.10) strand : +
36649116...36649264 | 36650982...36651044 | 36653128...36653181 | 36653364...36653452 |
36657641...36657767 | 36661196...36663576 |
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Exon(s) |
Start |
End |
Length |
is coding |
Exon 1
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1
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149
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149
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1
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Exon 3b
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150
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212
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63
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1
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Exon 4
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213
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266
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54
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1
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Exon 5
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267
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355
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89
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1
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Exon 6
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356
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482
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127
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1
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Exon 7
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483
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2863
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2381
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1
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ID |
Class |
Location |
Mutation |
Length |
is synonymous |
Source |
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Primary source |
NCBI : CCDS13926
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Nucleotide |
APOL1, mRNA isoform 1[NM_003661.3] : 169...1365
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Length |
1197
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Location |
Chromosome 22 (NC_000022.10) strand : +
36651001...36651044 | 36653128...36653181 | 36653364...36653452 | 36657641...36657767 |
36661196...36662078 |
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Start codon |
1
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Translation |
NP_003652.2 |
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1 |
GACTTTCACT |
TTCCCTTTCG |
AATTCCTCGG |
TATATCTTGG |
GGACTGGAGG |
ACCTGTCTGG |
TTATTATACA |
GACGCATAAC |
|
81 |
TGGAGGTGGG |
ATCCACACAG |
CTCAGAACAG |
CTGGATCTTG |
CTCAGTCTCT |
GCCAGGGGAA |
GATTCCTTGG |
AGGAGGCCCT |
|
161 |
GCAGCGACAT |
GGAGGGAGCT |
GCTTTGCTGA |
GAGTCTCTGT |
CCTCTGCATC |
TGGATGAGTG |
CACTTTTCCT |
TGGTGTGGGA |
|
241 |
GTGAGGGCAG |
AGGAAGCTGG |
AGCGAGGGTG |
CAACAAAACG |
TTCCAAGTGG |
GACAGATACT |
GGAGATCCTC |
AAAGTAAGCC |
|
321 |
CCTCGGTGAC |
TGGGCTGCTG |
GCACCATGGA |
CCCAGAGAGC |
AGTATCTTTA |
TTGAGGATGC |
CATTAAGTAT |
TTCAAGGAAA |
|
401 |
AAGTGAGCAC |
ACAGAATCTG |
CTACTCCTGC |
TGACTGATAA |
TGAGGCCTGG |
AACGGATTCG |
TGGCTGCTGC |
TGAACTGCCC |
|
481 |
AGGAATGAGG |
CAGATGAGCT |
CCGTAAAGCT |
CTGGACAACC |
TTGCAAGACA |
AATGATCATG |
AAAGACAAAA |
ACTGGCACGA |
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561 |
TAAAGGCCAG |
CAGTACAGAA |
ACTGGTTTCT |
GAAAGAGTTT |
CCTCGGTTGA |
AAAGTGAGCT |
TGAGGATAAC |
ATAAGAAGGC |
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641 |
TCCGTGCCCT |
TGCAGATGGG |
GTTCAGAAGG |
TCCACAAAGG |
CACCACCATC |
GCCAATGTGG |
TGTCTGGCTC |
TCTCAGCATT |
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721 |
TCCTCTGGCA |
TCCTGACCCT |
CGTCGGCATG |
GGTCTGGCAC |
CCTTCACAGA |
GGGAGGCAGC |
CTTGTACTCT |
TGGAACCTGG |
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801 |
GATGGAGTTG |
GGAATCACAG |
CCGCTTTGAC |
CGGGATTACC |
AGCAGTACCA |
TGGACTACGG |
AAAGAAGTGG |
TGGACACAAG |
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881 |
CCCAAGCCCA |
CGACCTGGTC |
ATCAAAAGCC |
TTGACAAATT |
GAAGGAGGTG |
AGGGAGTTTT |
TGGGTGAGAA |
CATATCCAAC |
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961 |
TTTCTTTCCT |
TAGCTGGCAA |
TACTTACCAA |
CTCACACGAG |
GCATTGGGAA |
GGACATCCGT |
GCCCTCAGAC |
GAGCCAGAGC |
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1041 |
CAATCTTCAG |
TCAGTACCGC |
ATGCCTCAGC |
CTCACGCCCC |
CGGGTCACTG |
AGCCAATCTC |
AGCTGAAAGC |
GGTGAACAGG |
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1121 |
TGGAGAGGGT |
TAATGAACCC |
AGCATCCTGG |
AAATGAGCAG |
AGGAGTCAAG |
CTCACGGATG |
TGGCCCCTGT |
AAGCTTCTTT |
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1201 |
CTTGTGCTGG |
ATGTAGTCTA |
CCTCGTGTAC |
GAATCAAAGC |
ACTTACATGA |
GGGGGCAAAG |
TCAGAGACAG |
CTGAGGAGCT |
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1281 |
GAAGAAGGTG |
GCTCAGGAGC |
TGGAGGAGAA |
GCTAAACATT |
CTCAACAATA |
ATTATAAGAT |
TCTGCAGGCG |
GACCAAGAAC |
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1361 |
TGTGACCACA |
GGGCAGGGCA |
GCCACCAGGA |
GAGATATGCC |
TGGCAGGGGC |
CAGGACAAAA |
TGCAAACTTT |
TTTTTTTTTC |
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1441 |
TGAGACAGAG |
TCTTGCTCTG |
TCGCCAAGTT |
GGAGTGCAAT |
GGTGCGATCT |
CAGCTCACTG |
CAAGCTCTGC |
CTCCCGTGTT |
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1521 |
CAAGCGATTC |
TCCTGCCTTG |
GCCTCCCAAG |
TAGCTGGGAC |
TACAGGCGCC |
TACCACCATG |
CCCAGCTAAT |
TTTTGTATTT |
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1601 |
TTAATAGAGA |
TGGGGTTTCA |
CCATGTTGGC |
CAGGATGGTC |
TCGATCTCCT |
GACCTCTTGA |
TCTGCCCACC |
TTGGCCTCCC |
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1681 |
AAAGTGCTGG |
GATTACAGGC |
GTGAGCCATC |
GCTTTTGACC |
CAAATGCAAA |
CATTTTATTA |
GGGGGATAAA |
GAGGGTGAGG |
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1761 |
TAAAGTTTAT |
GGAACTGAGT |
GTTAGGGACT |
TTGGCATTTC |
CATAGCTGAG |
CACAGCAGGG |
GAGGGGTTAA |
TGCAGATGGC |
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1841 |
AGTGCAGCAA |
GGAGAAGGCA |
GGAACATTGG |
AGCCTGCAAT |
AAGGGAAAAA |
TGGGAACTGG |
AGAGTGTGGG |
GAATGGGAAG |
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1921 |
AAGCAGTTTA |
CTTTAGACTA |
AAGAATATAT |
TGGGGGGCCG |
GGTGTAGTGG |
CTCATGCCTG |
TAATCCGAGC |
ACTTTGGGAG |
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2001 |
GCCAAGGCGG |
GCGGATCACG |
AGGTCAGGAG |
ATCGAGACCA |
TCCTGGCTAA |
CACAGTGAAA |
CCCCGTCTCT |
ACTAAAAATA |
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2081 |
CAAAAAATTA |
GCCGGGCATG |
GTGGCGGGCG |
CCTGTAGTTC |
CAGCTAACTG |
GGCGGCTGAG |
GCAGGAGAAT |
GGCGTGAACC |
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2161 |
TGGGAGGTGG |
AGCTTGCAGT |
GAGCCGAGAT |
ATCGCCACTG |
CACTCCAGCC |
TGGGTGACAG |
AGCGAGACTC |
CATCTCAAAA |
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2241 |
AAAAAAAAAA |
AAAGAATATA |
TTGACGGAAG |
AATAGAGAGG |
AGGCTTGAAG |
GAACCAGCAA |
TGAGAAGGCC |
AGGAAAAGAA |
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2321 |
AGAGCTGAAA |
ATGGAGAAAG |
CCCAAGAGTT |
AGAACAGTTG |
GATACAGGAG |
AAGAAACAGC |
GGCTCCACTA |
CAGACCCAGC |
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2401 |
CCCAGGTTCA |
ATGTCCTCCG |
AAGAATGAAG |
TCTTTCCCTG |
GTGATGGTCC |
CCTGCCCTGT |
CTTTCCAGCA |
TCCACTCTCC |
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2481 |
CTTGTCCTCC |
TGGGGGCATA |
TCTCAGTCAG |
GCAGCGGCTT |
CCTGATGATG |
GTCATTGGGG |
TGGTTGTCAT |
GTGATGGGTC |
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2561 |
CCCTCCAGGT |
TACTAAAGGG |
TGCATGTCCC |
CTGCTTGAAC |
ACTGAAGGGC |
AGGTGGTGGG |
CCATGGCCAT |
GGTCCCCAGC |
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2641 |
TGAGGAGCAG |
GTGTCCCTGA |
GAACCCAAAC |
TTCCCAGAGA |
GTATGTGAGA |
ACCAACCAAT |
GAAAACAGTC |
CCATCGCTCT |
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2721 |
TACCCGGTAA |
GTAAACAGTC |
AGAAAATTAG |
CATGAAAGCA |
GTTTAGCATT |
GGGAGGAAGC |
TCAGATCTCT |
AGAGCTGTCT |
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2801 |
TGTCGCCGCC |
CAGGATTGAC |
CTGTGTGTAA |
GTCCCAATAA |
ACTCACCTAC |
TCATCAAGCT |
GGAAAAAAAA |
AAAAAAAAAA |
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2881 |
AAAAA |
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>gi|211938437|ref|NM_003661.3|Apolipoprotein L, 1 (APOL1), transcript variant 1
GACTTTCACTTTCCCTTTCGAATTCCTCGGTATATCTTGGGGACTGGAGGACCTGTCTGGTTATTATACAGACGCATAAC
TGGAGGTGGGATCCACACAGCTCAGAACAGCTGGATCTTGCTCAGTCTCTGCCAGGGGAAGATTCCTTGGAGGAGGCCCT
GCAGCGACATGGAGGGAGCTGCTTTGCTGAGAGTCTCTGTCCTCTGCATCTGGATGAGTGCACTTTTCCTTGGTGTGGGA
GTGAGGGCAGAGGAAGCTGGAGCGAGGGTGCAACAAAACGTTCCAAGTGGGACAGATACTGGAGATCCTCAAAGTAAGCC
CCTCGGTGACTGGGCTGCTGGCACCATGGACCCAGAGAGCAGTATCTTTATTGAGGATGCCATTAAGTATTTCAAGGAAA
AAGTGAGCACACAGAATCTGCTACTCCTGCTGACTGATAATGAGGCCTGGAACGGATTCGTGGCTGCTGCTGAACTGCCC
AGGAATGAGGCAGATGAGCTCCGTAAAGCTCTGGACAACCTTGCAAGACAAATGATCATGAAAGACAAAAACTGGCACGA
TAAAGGCCAGCAGTACAGAAACTGGTTTCTGAAAGAGTTTCCTCGGTTGAAAAGTGAGCTTGAGGATAACATAAGAAGGC
TCCGTGCCCTTGCAGATGGGGTTCAGAAGGTCCACAAAGGCACCACCATCGCCAATGTGGTGTCTGGCTCTCTCAGCATT
TCCTCTGGCATCCTGACCCTCGTCGGCATGGGTCTGGCACCCTTCACAGAGGGAGGCAGCCTTGTACTCTTGGAACCTGG
GATGGAGTTGGGAATCACAGCCGCTTTGACCGGGATTACCAGCAGTACCATGGACTACGGAAAGAAGTGGTGGACACAAG
CCCAAGCCCACGACCTGGTCATCAAAAGCCTTGACAAATTGAAGGAGGTGAGGGAGTTTTTGGGTGAGAACATATCCAAC
TTTCTTTCCTTAGCTGGCAATACTTACCAACTCACACGAGGCATTGGGAAGGACATCCGTGCCCTCAGACGAGCCAGAGC
CAATCTTCAGTCAGTACCGCATGCCTCAGCCTCACGCCCCCGGGTCACTGAGCCAATCTCAGCTGAAAGCGGTGAACAGG
TGGAGAGGGTTAATGAACCCAGCATCCTGGAAATGAGCAGAGGAGTCAAGCTCACGGATGTGGCCCCTGTAAGCTTCTTT
CTTGTGCTGGATGTAGTCTACCTCGTGTACGAATCAAAGCACTTACATGAGGGGGCAAAGTCAGAGACAGCTGAGGAGCT
GAAGAAGGTGGCTCAGGAGCTGGAGGAGAAGCTAAACATTCTCAACAATAATTATAAGATTCTGCAGGCGGACCAAGAAC
TGTGACCACAGGGCAGGGCAGCCACCAGGAGAGATATGCCTGGCAGGGGCCAGGACAAAATGCAAACTTTTTTTTTTTTC
TGAGACAGAGTCTTGCTCTGTCGCCAAGTTGGAGTGCAATGGTGCGATCTCAGCTCACTGCAAGCTCTGCCTCCCGTGTT
CAAGCGATTCTCCTGCCTTGGCCTCCCAAGTAGCTGGGACTACAGGCGCCTACCACCATGCCCAGCTAATTTTTGTATTT
TTAATAGAGATGGGGTTTCACCATGTTGGCCAGGATGGTCTCGATCTCCTGACCTCTTGATCTGCCCACCTTGGCCTCCC
AAAGTGCTGGGATTACAGGCGTGAGCCATCGCTTTTGACCCAAATGCAAACATTTTATTAGGGGGATAAAGAGGGTGAGG
TAAAGTTTATGGAACTGAGTGTTAGGGACTTTGGCATTTCCATAGCTGAGCACAGCAGGGGAGGGGTTAATGCAGATGGC
AGTGCAGCAAGGAGAAGGCAGGAACATTGGAGCCTGCAATAAGGGAAAAATGGGAACTGGAGAGTGTGGGGAATGGGAAG
AAGCAGTTTACTTTAGACTAAAGAATATATTGGGGGGCCGGGTGTAGTGGCTCATGCCTGTAATCCGAGCACTTTGGGAG
GCCAAGGCGGGCGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACACAGTGAAACCCCGTCTCTACTAAAAATA
CAAAAAATTAGCCGGGCATGGTGGCGGGCGCCTGTAGTTCCAGCTAACTGGGCGGCTGAGGCAGGAGAATGGCGTGAACC
TGGGAGGTGGAGCTTGCAGTGAGCCGAGATATCGCCACTGCACTCCAGCCTGGGTGACAGAGCGAGACTCCATCTCAAAA
AAAAAAAAAAAAAGAATATATTGACGGAAGAATAGAGAGGAGGCTTGAAGGAACCAGCAATGAGAAGGCCAGGAAAAGAA
AGAGCTGAAAATGGAGAAAGCCCAAGAGTTAGAACAGTTGGATACAGGAGAAGAAACAGCGGCTCCACTACAGACCCAGC
CCCAGGTTCAATGTCCTCCGAAGAATGAAGTCTTTCCCTGGTGATGGTCCCCTGCCCTGTCTTTCCAGCATCCACTCTCC
CTTGTCCTCCTGGGGGCATATCTCAGTCAGGCAGCGGCTTCCTGATGATGGTCATTGGGGTGGTTGTCATGTGATGGGTC
CCCTCCAGGTTACTAAAGGGTGCATGTCCCCTGCTTGAACACTGAAGGGCAGGTGGTGGGCCATGGCCATGGTCCCCAGC
TGAGGAGCAGGTGTCCCTGAGAACCCAAACTTCCCAGAGAGTATGTGAGAACCAACCAATGAAAACAGTCCCATCGCTCT
TACCCGGTAAGTAAACAGTCAGAAAATTAGCATGAAAGCAGTTTAGCATTGGGAGGAAGCTCAGATCTCTAGAGCTGTCT
TGTCGCCGCCCAGGATTGACCTGTGTGTAAGTCCCAATAAACTCACCTACTCATCAAGCTGGAAAAAAAAAAAAAAAAAA
AAAAA
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| |
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Primary source |
RefSeq : NM_145343.2 (GI:211938438)
|
Name |
Apolipoprotein L, 1 (APOL1), transcript variant 2
|
Type of transcript |
mRNA
|
Organism |
Homo sapiens
|
Length |
3039 nt
|
Map |
22q13.1
|
Location |
Chromosome 22 (NC_000022.10) strand : +
36649116...36649264 | 36649883...36650036 | 36650982...36651044 | 36653128...36653181 |
36653364...36653452 | 36657641...36657767 | 36661196...36663576 |
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|
Exon(s) |
Start |
End |
Length |
is coding |
Exon 1
|
1
|
149
|
149
|
1
|
Exon 2
|
150
|
303
|
154
|
1
|
Exon 3b
|
304
|
366
|
63
|
1
|
Exon 4
|
367
|
420
|
54
|
1
|
Exon 5
|
421
|
509
|
89
|
1
|
Exon 6
|
510
|
636
|
127
|
1
|
Exon 7
|
637
|
3017
|
2381
|
1
|
|
|
|
|
|
|
|
|
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|
ID |
Class |
Location |
Mutation |
Length |
is synonymous |
Source |
|
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|
Primary source |
NCBI : CCDS13925
|
Nucleotide |
APOL1, mRNA isoform 2[NM_145343.2] : 275...1519
|
Length |
1245
|
Location |
Chromosome 22 (NC_000022.10) strand : +
36650008...36650036 | 36650982...36651044 | 36653128...36653181 | 36653364...36653452 |
36657641...36657767 | 36661196...36662078 |
|
Start codon |
1
|
Translation |
NP_663318.1 |
|
|
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|
|
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|
|
1 |
GACTTTCACT |
TTCCCTTTCG |
AATTCCTCGG |
TATATCTTGG |
GGACTGGAGG |
ACCTGTCTGG |
TTATTATACA |
GACGCATAAC |
|
81 |
TGGAGGTGGG |
ATCCACACAG |
CTCAGAACAG |
CTGGATCTTG |
CTCAGTCTCT |
GCCAGGGGAA |
GATTCCTTGA |
CTTCTGGGGT |
|
161 |
GATGGAGAAG |
AAACAGGCTG |
TGCTGTGTCC |
CTAATGGGAA |
ACGTGGCTGA |
GACAGGGGAG |
TGAGAAGGGT |
GCGTTGCAGA |
|
241 |
ATGGTGCCTG |
TGGCATGATG |
CCAGCTTTGC |
AATCATGAGA |
TTCAAAAGCC |
ACACTGTGGA |
ATTGAGGAGG |
CCCTGCAGCG |
|
321 |
ACATGGAGGG |
AGCTGCTTTG |
CTGAGAGTCT |
CTGTCCTCTG |
CATCTGGATG |
AGTGCACTTT |
TCCTTGGTGT |
GGGAGTGAGG |
|
401 |
GCAGAGGAAG |
CTGGAGCGAG |
GGTGCAACAA |
AACGTTCCAA |
GTGGGACAGA |
TACTGGAGAT |
CCTCAAAGTA |
AGCCCCTCGG |
|
481 |
TGACTGGGCT |
GCTGGCACCA |
TGGACCCAGA |
GAGCAGTATC |
TTTATTGAGG |
ATGCCATTAA |
GTATTTCAAG |
GAAAAAGTGA |
|
561 |
GCACACAGAA |
TCTGCTACTC |
CTGCTGACTG |
ATAATGAGGC |
CTGGAACGGA |
TTCGTGGCTG |
CTGCTGAACT |
GCCCAGGAAT |
|
641 |
GAGGCAGATG |
AGCTCCGTAA |
AGCTCTGGAC |
AACCTTGCAA |
GACAAATGAT |
CATGAAAGAC |
AAAAACTGGC |
ACGATAAAGG |
|
721 |
CCAGCAGTAC |
AGAAACTGGT |
TTCTGAAAGA |
GTTTCCTCGG |
TTGAAAAGTG |
AGCTTGAGGA |
TAACATAAGA |
AGGCTCCGTG |
|
801 |
CCCTTGCAGA |
TGGGGTTCAG |
AAGGTCCACA |
AAGGCACCAC |
CATCGCCAAT |
GTGGTGTCTG |
GCTCTCTCAG |
CATTTCCTCT |
|
881 |
GGCATCCTGA |
CCCTCGTCGG |
CATGGGTCTG |
GCACCCTTCA |
CAGAGGGAGG |
CAGCCTTGTA |
CTCTTGGAAC |
CTGGGATGGA |
|
961 |
GTTGGGAATC |
ACAGCCGCTT |
TGACCGGGAT |
TACCAGCAGT |
ACCATGGACT |
ACGGAAAGAA |
GTGGTGGACA |
CAAGCCCAAG |
|
1041 |
CCCACGACCT |
GGTCATCAAA |
AGCCTTGACA |
AATTGAAGGA |
GGTGAGGGAG |
TTTTTGGGTG |
AGAACATATC |
CAACTTTCTT |
|
1121 |
TCCTTAGCTG |
GCAATACTTA |
CCAACTCACA |
CGAGGCATTG |
GGAAGGACAT |
CCGTGCCCTC |
AGACGAGCCA |
GAGCCAATCT |
|
1201 |
TCAGTCAGTA |
CCGCATGCCT |
CAGCCTCACG |
CCCCCGGGTC |
ACTGAGCCAA |
TCTCAGCTGA |
AAGCGGTGAA |
CAGGTGGAGA |
|
1281 |
GGGTTAATGA |
ACCCAGCATC |
CTGGAAATGA |
GCAGAGGAGT |
CAAGCTCACG |
GATGTGGCCC |
CTGTAAGCTT |
CTTTCTTGTG |
|
1361 |
CTGGATGTAG |
TCTACCTCGT |
GTACGAATCA |
AAGCACTTAC |
ATGAGGGGGC |
AAAGTCAGAG |
ACAGCTGAGG |
AGCTGAAGAA |
|
1441 |
GGTGGCTCAG |
GAGCTGGAGG |
AGAAGCTAAA |
CATTCTCAAC |
AATAATTATA |
AGATTCTGCA |
GGCGGACCAA |
GAACTGTGAC |
|
1521 |
CACAGGGCAG |
GGCAGCCACC |
AGGAGAGATA |
TGCCTGGCAG |
GGGCCAGGAC |
AAAATGCAAA |
CTTTTTTTTT |
TTTCTGAGAC |
|
1601 |
AGAGTCTTGC |
TCTGTCGCCA |
AGTTGGAGTG |
CAATGGTGCG |
ATCTCAGCTC |
ACTGCAAGCT |
CTGCCTCCCG |
TGTTCAAGCG |
|
1681 |
ATTCTCCTGC |
CTTGGCCTCC |
CAAGTAGCTG |
GGACTACAGG |
CGCCTACCAC |
CATGCCCAGC |
TAATTTTTGT |
ATTTTTAATA |
|
1761 |
GAGATGGGGT |
TTCACCATGT |
TGGCCAGGAT |
GGTCTCGATC |
TCCTGACCTC |
TTGATCTGCC |
CACCTTGGCC |
TCCCAAAGTG |
|
1841 |
CTGGGATTAC |
AGGCGTGAGC |
CATCGCTTTT |
GACCCAAATG |
CAAACATTTT |
ATTAGGGGGA |
TAAAGAGGGT |
GAGGTAAAGT |
|
1921 |
TTATGGAACT |
GAGTGTTAGG |
GACTTTGGCA |
TTTCCATAGC |
TGAGCACAGC |
AGGGGAGGGG |
TTAATGCAGA |
TGGCAGTGCA |
|
2001 |
GCAAGGAGAA |
GGCAGGAACA |
TTGGAGCCTG |
CAATAAGGGA |
AAAATGGGAA |
CTGGAGAGTG |
TGGGGAATGG |
GAAGAAGCAG |
|
2081 |
TTTACTTTAG |
ACTAAAGAAT |
ATATTGGGGG |
GCCGGGTGTA |
GTGGCTCATG |
CCTGTAATCC |
GAGCACTTTG |
GGAGGCCAAG |
|
2161 |
GCGGGCGGAT |
CACGAGGTCA |
GGAGATCGAG |
ACCATCCTGG |
CTAACACAGT |
GAAACCCCGT |
CTCTACTAAA |
AATACAAAAA |
|
2241 |
ATTAGCCGGG |
CATGGTGGCG |
GGCGCCTGTA |
GTTCCAGCTA |
ACTGGGCGGC |
TGAGGCAGGA |
GAATGGCGTG |
AACCTGGGAG |
|
2321 |
GTGGAGCTTG |
CAGTGAGCCG |
AGATATCGCC |
ACTGCACTCC |
AGCCTGGGTG |
ACAGAGCGAG |
ACTCCATCTC |
AAAAAAAAAA |
|
2401 |
AAAAAAAGAA |
TATATTGACG |
GAAGAATAGA |
GAGGAGGCTT |
GAAGGAACCA |
GCAATGAGAA |
GGCCAGGAAA |
AGAAAGAGCT |
|
2481 |
GAAAATGGAG |
AAAGCCCAAG |
AGTTAGAACA |
GTTGGATACA |
GGAGAAGAAA |
CAGCGGCTCC |
ACTACAGACC |
CAGCCCCAGG |
|
2561 |
TTCAATGTCC |
TCCGAAGAAT |
GAAGTCTTTC |
CCTGGTGATG |
GTCCCCTGCC |
CTGTCTTTCC |
AGCATCCACT |
CTCCCTTGTC |
|
2641 |
CTCCTGGGGG |
CATATCTCAG |
TCAGGCAGCG |
GCTTCCTGAT |
GATGGTCATT |
GGGGTGGTTG |
TCATGTGATG |
GGTCCCCTCC |
|
2721 |
AGGTTACTAA |
AGGGTGCATG |
TCCCCTGCTT |
GAACACTGAA |
GGGCAGGTGG |
TGGGCCATGG |
CCATGGTCCC |
CAGCTGAGGA |
|
2801 |
GCAGGTGTCC |
CTGAGAACCC |
AAACTTCCCA |
GAGAGTATGT |
GAGAACCAAC |
CAATGAAAAC |
AGTCCCATCG |
CTCTTACCCG |
|
2881 |
GTAAGTAAAC |
AGTCAGAAAA |
TTAGCATGAA |
AGCAGTTTAG |
CATTGGGAGG |
AAGCTCAGAT |
CTCTAGAGCT |
GTCTTGTCGC |
|
2961 |
CGCCCAGGAT |
TGACCTGTGT |
GTAAGTCCCA |
ATAAACTCAC |
CTACTCATCA |
AGCTGGAAAA |
AAAAAAAAAA |
AAAAAAAAA |
|
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|
|
>gi|211938438|ref|NM_145343.2|Apolipoprotein L, 1 (APOL1), transcript variant 2
GACTTTCACTTTCCCTTTCGAATTCCTCGGTATATCTTGGGGACTGGAGGACCTGTCTGGTTATTATACAGACGCATAAC
TGGAGGTGGGATCCACACAGCTCAGAACAGCTGGATCTTGCTCAGTCTCTGCCAGGGGAAGATTCCTTGACTTCTGGGGT
GATGGAGAAGAAACAGGCTGTGCTGTGTCCCTAATGGGAAACGTGGCTGAGACAGGGGAGTGAGAAGGGTGCGTTGCAGA
ATGGTGCCTGTGGCATGATGCCAGCTTTGCAATCATGAGATTCAAAAGCCACACTGTGGAATTGAGGAGGCCCTGCAGCG
ACATGGAGGGAGCTGCTTTGCTGAGAGTCTCTGTCCTCTGCATCTGGATGAGTGCACTTTTCCTTGGTGTGGGAGTGAGG
GCAGAGGAAGCTGGAGCGAGGGTGCAACAAAACGTTCCAAGTGGGACAGATACTGGAGATCCTCAAAGTAAGCCCCTCGG
TGACTGGGCTGCTGGCACCATGGACCCAGAGAGCAGTATCTTTATTGAGGATGCCATTAAGTATTTCAAGGAAAAAGTGA
GCACACAGAATCTGCTACTCCTGCTGACTGATAATGAGGCCTGGAACGGATTCGTGGCTGCTGCTGAACTGCCCAGGAAT
GAGGCAGATGAGCTCCGTAAAGCTCTGGACAACCTTGCAAGACAAATGATCATGAAAGACAAAAACTGGCACGATAAAGG
CCAGCAGTACAGAAACTGGTTTCTGAAAGAGTTTCCTCGGTTGAAAAGTGAGCTTGAGGATAACATAAGAAGGCTCCGTG
CCCTTGCAGATGGGGTTCAGAAGGTCCACAAAGGCACCACCATCGCCAATGTGGTGTCTGGCTCTCTCAGCATTTCCTCT
GGCATCCTGACCCTCGTCGGCATGGGTCTGGCACCCTTCACAGAGGGAGGCAGCCTTGTACTCTTGGAACCTGGGATGGA
GTTGGGAATCACAGCCGCTTTGACCGGGATTACCAGCAGTACCATGGACTACGGAAAGAAGTGGTGGACACAAGCCCAAG
CCCACGACCTGGTCATCAAAAGCCTTGACAAATTGAAGGAGGTGAGGGAGTTTTTGGGTGAGAACATATCCAACTTTCTT
TCCTTAGCTGGCAATACTTACCAACTCACACGAGGCATTGGGAAGGACATCCGTGCCCTCAGACGAGCCAGAGCCAATCT
TCAGTCAGTACCGCATGCCTCAGCCTCACGCCCCCGGGTCACTGAGCCAATCTCAGCTGAAAGCGGTGAACAGGTGGAGA
GGGTTAATGAACCCAGCATCCTGGAAATGAGCAGAGGAGTCAAGCTCACGGATGTGGCCCCTGTAAGCTTCTTTCTTGTG
CTGGATGTAGTCTACCTCGTGTACGAATCAAAGCACTTACATGAGGGGGCAAAGTCAGAGACAGCTGAGGAGCTGAAGAA
GGTGGCTCAGGAGCTGGAGGAGAAGCTAAACATTCTCAACAATAATTATAAGATTCTGCAGGCGGACCAAGAACTGTGAC
CACAGGGCAGGGCAGCCACCAGGAGAGATATGCCTGGCAGGGGCCAGGACAAAATGCAAACTTTTTTTTTTTTCTGAGAC
AGAGTCTTGCTCTGTCGCCAAGTTGGAGTGCAATGGTGCGATCTCAGCTCACTGCAAGCTCTGCCTCCCGTGTTCAAGCG
ATTCTCCTGCCTTGGCCTCCCAAGTAGCTGGGACTACAGGCGCCTACCACCATGCCCAGCTAATTTTTGTATTTTTAATA
GAGATGGGGTTTCACCATGTTGGCCAGGATGGTCTCGATCTCCTGACCTCTTGATCTGCCCACCTTGGCCTCCCAAAGTG
CTGGGATTACAGGCGTGAGCCATCGCTTTTGACCCAAATGCAAACATTTTATTAGGGGGATAAAGAGGGTGAGGTAAAGT
TTATGGAACTGAGTGTTAGGGACTTTGGCATTTCCATAGCTGAGCACAGCAGGGGAGGGGTTAATGCAGATGGCAGTGCA
GCAAGGAGAAGGCAGGAACATTGGAGCCTGCAATAAGGGAAAAATGGGAACTGGAGAGTGTGGGGAATGGGAAGAAGCAG
TTTACTTTAGACTAAAGAATATATTGGGGGGCCGGGTGTAGTGGCTCATGCCTGTAATCCGAGCACTTTGGGAGGCCAAG
GCGGGCGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACACAGTGAAACCCCGTCTCTACTAAAAATACAAAAA
ATTAGCCGGGCATGGTGGCGGGCGCCTGTAGTTCCAGCTAACTGGGCGGCTGAGGCAGGAGAATGGCGTGAACCTGGGAG
GTGGAGCTTGCAGTGAGCCGAGATATCGCCACTGCACTCCAGCCTGGGTGACAGAGCGAGACTCCATCTCAAAAAAAAAA
AAAAAAAGAATATATTGACGGAAGAATAGAGAGGAGGCTTGAAGGAACCAGCAATGAGAAGGCCAGGAAAAGAAAGAGCT
GAAAATGGAGAAAGCCCAAGAGTTAGAACAGTTGGATACAGGAGAAGAAACAGCGGCTCCACTACAGACCCAGCCCCAGG
TTCAATGTCCTCCGAAGAATGAAGTCTTTCCCTGGTGATGGTCCCCTGCCCTGTCTTTCCAGCATCCACTCTCCCTTGTC
CTCCTGGGGGCATATCTCAGTCAGGCAGCGGCTTCCTGATGATGGTCATTGGGGTGGTTGTCATGTGATGGGTCCCCTCC
AGGTTACTAAAGGGTGCATGTCCCCTGCTTGAACACTGAAGGGCAGGTGGTGGGCCATGGCCATGGTCCCCAGCTGAGGA
GCAGGTGTCCCTGAGAACCCAAACTTCCCAGAGAGTATGTGAGAACCAACCAATGAAAACAGTCCCATCGCTCTTACCCG
GTAAGTAAACAGTCAGAAAATTAGCATGAAAGCAGTTTAGCATTGGGAGGAAGCTCAGATCTCTAGAGCTGTCTTGTCGC
CGCCCAGGATTGACCTGTGTGTAAGTCCCAATAAACTCACCTACTCATCAAGCTGGAAAAAAAAAAAAAAAAAAAAAAA
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|
|
Primary source |
RefSeq : NM_001136540.1 (GI:211938439)
|
Name |
Apolipoprotein L, 1 (APOL1), transcript variant 3
|
Type of transcript |
mRNA
|
Organism |
Homo sapiens
|
Length |
2924 nt
|
Map |
22q13.1
|
Location |
Chromosome 22 (NC_000022.10) strand : +
36649116...36649264 | 36650943...36651044 | 36653128...36653181 | 36653364...36653452 |
36657641...36657767 | 36661196...36663576 |
|
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|
Exon(s) |
Start |
End |
Length |
is coding |
Exon 1
|
1
|
149
|
149
|
1
|
Exon 3a
|
150
|
251
|
102
|
1
|
Exon 4
|
252
|
305
|
54
|
1
|
Exon 5
|
306
|
394
|
89
|
1
|
Exon 6
|
395
|
521
|
127
|
1
|
Exon 7
|
522
|
2902
|
2381
|
1
|
|
|
|
|
|
|
|
|
|
|
|
|
ID |
Class |
Location |
Mutation |
Length |
is synonymous |
Source |
|
|
|
|
|
|
|
|
|
|
|
|
Primary source |
NCBI : CCDS13926
|
Nucleotide |
APOL1, mRNA isoform 3[NM_001136540.1] : 208...1404
|
Length |
1197
|
Location |
Chromosome 22 (NC_000022.10) strand : +
36651001...36651044 | 36653128...36653181 | 36653364...36653452 | 36657641...36657767 |
36661196...36662078 |
|
Start codon |
1
|
Translation |
NP_001130012.1 |
|
|
|
|
|
|
|
|
|
|
|
|
1 |
GACTTTCACT |
TTCCCTTTCG |
AATTCCTCGG |
TATATCTTGG |
GGACTGGAGG |
ACCTGTCTGG |
TTATTATACA |
GACGCATAAC |
|
81 |
TGGAGGTGGG |
ATCCACACAG |
CTCAGAACAG |
CTGGATCTTG |
CTCAGTCTCT |
GCCAGGGGAA |
GATTCCTTGG |
AGGAGCACAC |
|
161 |
TGTCTCAACC |
CCTCTTTTCC |
TGCTCAAGGA |
GGAGGCCCTG |
CAGCGACATG |
GAGGGAGCTG |
CTTTGCTGAG |
AGTCTCTGTC |
|
241 |
CTCTGCATCT |
GGATGAGTGC |
ACTTTTCCTT |
GGTGTGGGAG |
TGAGGGCAGA |
GGAAGCTGGA |
GCGAGGGTGC |
AACAAAACGT |
|
321 |
TCCAAGTGGG |
ACAGATACTG |
GAGATCCTCA |
AAGTAAGCCC |
CTCGGTGACT |
GGGCTGCTGG |
CACCATGGAC |
CCAGAGAGCA |
|
401 |
GTATCTTTAT |
TGAGGATGCC |
ATTAAGTATT |
TCAAGGAAAA |
AGTGAGCACA |
CAGAATCTGC |
TACTCCTGCT |
GACTGATAAT |
|
481 |
GAGGCCTGGA |
ACGGATTCGT |
GGCTGCTGCT |
GAACTGCCCA |
GGAATGAGGC |
AGATGAGCTC |
CGTAAAGCTC |
TGGACAACCT |
|
561 |
TGCAAGACAA |
ATGATCATGA |
AAGACAAAAA |
CTGGCACGAT |
AAAGGCCAGC |
AGTACAGAAA |
CTGGTTTCTG |
AAAGAGTTTC |
|
641 |
CTCGGTTGAA |
AAGTGAGCTT |
GAGGATAACA |
TAAGAAGGCT |
CCGTGCCCTT |
GCAGATGGGG |
TTCAGAAGGT |
CCACAAAGGC |
|
721 |
ACCACCATCG |
CCAATGTGGT |
GTCTGGCTCT |
CTCAGCATTT |
CCTCTGGCAT |
CCTGACCCTC |
GTCGGCATGG |
GTCTGGCACC |
|
801 |
CTTCACAGAG |
GGAGGCAGCC |
TTGTACTCTT |
GGAACCTGGG |
ATGGAGTTGG |
GAATCACAGC |
CGCTTTGACC |
GGGATTACCA |
|
881 |
GCAGTACCAT |
GGACTACGGA |
AAGAAGTGGT |
GGACACAAGC |
CCAAGCCCAC |
GACCTGGTCA |
TCAAAAGCCT |
TGACAAATTG |
|
961 |
AAGGAGGTGA |
GGGAGTTTTT |
GGGTGAGAAC |
ATATCCAACT |
TTCTTTCCTT |
AGCTGGCAAT |
ACTTACCAAC |
TCACACGAGG |
|
1041 |
CATTGGGAAG |
GACATCCGTG |
CCCTCAGACG |
AGCCAGAGCC |
AATCTTCAGT |
CAGTACCGCA |
TGCCTCAGCC |
TCACGCCCCC |
|
1121 |
GGGTCACTGA |
GCCAATCTCA |
GCTGAAAGCG |
GTGAACAGGT |
GGAGAGGGTT |
AATGAACCCA |
GCATCCTGGA |
AATGAGCAGA |
|
1201 |
GGAGTCAAGC |
TCACGGATGT |
GGCCCCTGTA |
AGCTTCTTTC |
TTGTGCTGGA |
TGTAGTCTAC |
CTCGTGTACG |
AATCAAAGCA |
|
1281 |
CTTACATGAG |
GGGGCAAAGT |
CAGAGACAGC |
TGAGGAGCTG |
AAGAAGGTGG |
CTCAGGAGCT |
GGAGGAGAAG |
CTAAACATTC |
|
1361 |
TCAACAATAA |
TTATAAGATT |
CTGCAGGCGG |
ACCAAGAACT |
GTGACCACAG |
GGCAGGGCAG |
CCACCAGGAG |
AGATATGCCT |
|
1441 |
GGCAGGGGCC |
AGGACAAAAT |
GCAAACTTTT |
TTTTTTTTCT |
GAGACAGAGT |
CTTGCTCTGT |
CGCCAAGTTG |
GAGTGCAATG |
|
1521 |
GTGCGATCTC |
AGCTCACTGC |
AAGCTCTGCC |
TCCCGTGTTC |
AAGCGATTCT |
CCTGCCTTGG |
CCTCCCAAGT |
AGCTGGGACT |
|
1601 |
ACAGGCGCCT |
ACCACCATGC |
CCAGCTAATT |
TTTGTATTTT |
TAATAGAGAT |
GGGGTTTCAC |
CATGTTGGCC |
AGGATGGTCT |
|
1681 |
CGATCTCCTG |
ACCTCTTGAT |
CTGCCCACCT |
TGGCCTCCCA |
AAGTGCTGGG |
ATTACAGGCG |
TGAGCCATCG |
CTTTTGACCC |
|
1761 |
AAATGCAAAC |
ATTTTATTAG |
GGGGATAAAG |
AGGGTGAGGT |
AAAGTTTATG |
GAACTGAGTG |
TTAGGGACTT |
TGGCATTTCC |
|
1841 |
ATAGCTGAGC |
ACAGCAGGGG |
AGGGGTTAAT |
GCAGATGGCA |
GTGCAGCAAG |
GAGAAGGCAG |
GAACATTGGA |
GCCTGCAATA |
|
1921 |
AGGGAAAAAT |
GGGAACTGGA |
GAGTGTGGGG |
AATGGGAAGA |
AGCAGTTTAC |
TTTAGACTAA |
AGAATATATT |
GGGGGGCCGG |
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2001 |
GTGTAGTGGC |
TCATGCCTGT |
AATCCGAGCA |
CTTTGGGAGG |
CCAAGGCGGG |
CGGATCACGA |
GGTCAGGAGA |
TCGAGACCAT |
|
2081 |
CCTGGCTAAC |
ACAGTGAAAC |
CCCGTCTCTA |
CTAAAAATAC |
AAAAAATTAG |
CCGGGCATGG |
TGGCGGGCGC |
CTGTAGTTCC |
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2161 |
AGCTAACTGG |
GCGGCTGAGG |
CAGGAGAATG |
GCGTGAACCT |
GGGAGGTGGA |
GCTTGCAGTG |
AGCCGAGATA |
TCGCCACTGC |
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2241 |
ACTCCAGCCT |
GGGTGACAGA |
GCGAGACTCC |
ATCTCAAAAA |
AAAAAAAAAA |
AAGAATATAT |
TGACGGAAGA |
ATAGAGAGGA |
|
2321 |
GGCTTGAAGG |
AACCAGCAAT |
GAGAAGGCCA |
GGAAAAGAAA |
GAGCTGAAAA |
TGGAGAAAGC |
CCAAGAGTTA |
GAACAGTTGG |
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2401 |
ATACAGGAGA |
AGAAACAGCG |
GCTCCACTAC |
AGACCCAGCC |
CCAGGTTCAA |
TGTCCTCCGA |
AGAATGAAGT |
CTTTCCCTGG |
|
2481 |
TGATGGTCCC |
CTGCCCTGTC |
TTTCCAGCAT |
CCACTCTCCC |
TTGTCCTCCT |
GGGGGCATAT |
CTCAGTCAGG |
CAGCGGCTTC |
|
2561 |
CTGATGATGG |
TCATTGGGGT |
GGTTGTCATG |
TGATGGGTCC |
CCTCCAGGTT |
ACTAAAGGGT |
GCATGTCCCC |
TGCTTGAACA |
|
2641 |
CTGAAGGGCA |
GGTGGTGGGC |
CATGGCCATG |
GTCCCCAGCT |
GAGGAGCAGG |
TGTCCCTGAG |
AACCCAAACT |
TCCCAGAGAG |
|
2721 |
TATGTGAGAA |
CCAACCAATG |
AAAACAGTCC |
CATCGCTCTT |
ACCCGGTAAG |
TAAACAGTCA |
GAAAATTAGC |
ATGAAAGCAG |
|
2801 |
TTTAGCATTG |
GGAGGAAGCT |
CAGATCTCTA |
GAGCTGTCTT |
GTCGCCGCCC |
AGGATTGACC |
TGTGTGTAAG |
TCCCAATAAA |
|
2881 |
CTCACCTACT |
CATCAAGCTG |
GAAAAAAAAA |
AAAAAAAAAA |
AAAA |
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>gi|211938439|ref|NM_001136540.1|Apolipoprotein L, 1 (APOL1), transcript variant 3
GACTTTCACTTTCCCTTTCGAATTCCTCGGTATATCTTGGGGACTGGAGGACCTGTCTGGTTATTATACAGACGCATAAC
TGGAGGTGGGATCCACACAGCTCAGAACAGCTGGATCTTGCTCAGTCTCTGCCAGGGGAAGATTCCTTGGAGGAGCACAC
TGTCTCAACCCCTCTTTTCCTGCTCAAGGAGGAGGCCCTGCAGCGACATGGAGGGAGCTGCTTTGCTGAGAGTCTCTGTC
CTCTGCATCTGGATGAGTGCACTTTTCCTTGGTGTGGGAGTGAGGGCAGAGGAAGCTGGAGCGAGGGTGCAACAAAACGT
TCCAAGTGGGACAGATACTGGAGATCCTCAAAGTAAGCCCCTCGGTGACTGGGCTGCTGGCACCATGGACCCAGAGAGCA
GTATCTTTATTGAGGATGCCATTAAGTATTTCAAGGAAAAAGTGAGCACACAGAATCTGCTACTCCTGCTGACTGATAAT
GAGGCCTGGAACGGATTCGTGGCTGCTGCTGAACTGCCCAGGAATGAGGCAGATGAGCTCCGTAAAGCTCTGGACAACCT
TGCAAGACAAATGATCATGAAAGACAAAAACTGGCACGATAAAGGCCAGCAGTACAGAAACTGGTTTCTGAAAGAGTTTC
CTCGGTTGAAAAGTGAGCTTGAGGATAACATAAGAAGGCTCCGTGCCCTTGCAGATGGGGTTCAGAAGGTCCACAAAGGC
ACCACCATCGCCAATGTGGTGTCTGGCTCTCTCAGCATTTCCTCTGGCATCCTGACCCTCGTCGGCATGGGTCTGGCACC
CTTCACAGAGGGAGGCAGCCTTGTACTCTTGGAACCTGGGATGGAGTTGGGAATCACAGCCGCTTTGACCGGGATTACCA
GCAGTACCATGGACTACGGAAAGAAGTGGTGGACACAAGCCCAAGCCCACGACCTGGTCATCAAAAGCCTTGACAAATTG
AAGGAGGTGAGGGAGTTTTTGGGTGAGAACATATCCAACTTTCTTTCCTTAGCTGGCAATACTTACCAACTCACACGAGG
CATTGGGAAGGACATCCGTGCCCTCAGACGAGCCAGAGCCAATCTTCAGTCAGTACCGCATGCCTCAGCCTCACGCCCCC
GGGTCACTGAGCCAATCTCAGCTGAAAGCGGTGAACAGGTGGAGAGGGTTAATGAACCCAGCATCCTGGAAATGAGCAGA
GGAGTCAAGCTCACGGATGTGGCCCCTGTAAGCTTCTTTCTTGTGCTGGATGTAGTCTACCTCGTGTACGAATCAAAGCA
CTTACATGAGGGGGCAAAGTCAGAGACAGCTGAGGAGCTGAAGAAGGTGGCTCAGGAGCTGGAGGAGAAGCTAAACATTC
TCAACAATAATTATAAGATTCTGCAGGCGGACCAAGAACTGTGACCACAGGGCAGGGCAGCCACCAGGAGAGATATGCCT
GGCAGGGGCCAGGACAAAATGCAAACTTTTTTTTTTTTCTGAGACAGAGTCTTGCTCTGTCGCCAAGTTGGAGTGCAATG
GTGCGATCTCAGCTCACTGCAAGCTCTGCCTCCCGTGTTCAAGCGATTCTCCTGCCTTGGCCTCCCAAGTAGCTGGGACT
ACAGGCGCCTACCACCATGCCCAGCTAATTTTTGTATTTTTAATAGAGATGGGGTTTCACCATGTTGGCCAGGATGGTCT
CGATCTCCTGACCTCTTGATCTGCCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCATCGCTTTTGACCC
AAATGCAAACATTTTATTAGGGGGATAAAGAGGGTGAGGTAAAGTTTATGGAACTGAGTGTTAGGGACTTTGGCATTTCC
ATAGCTGAGCACAGCAGGGGAGGGGTTAATGCAGATGGCAGTGCAGCAAGGAGAAGGCAGGAACATTGGAGCCTGCAATA
AGGGAAAAATGGGAACTGGAGAGTGTGGGGAATGGGAAGAAGCAGTTTACTTTAGACTAAAGAATATATTGGGGGGCCGG
GTGTAGTGGCTCATGCCTGTAATCCGAGCACTTTGGGAGGCCAAGGCGGGCGGATCACGAGGTCAGGAGATCGAGACCAT
CCTGGCTAACACAGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCGGGCATGGTGGCGGGCGCCTGTAGTTCC
AGCTAACTGGGCGGCTGAGGCAGGAGAATGGCGTGAACCTGGGAGGTGGAGCTTGCAGTGAGCCGAGATATCGCCACTGC
ACTCCAGCCTGGGTGACAGAGCGAGACTCCATCTCAAAAAAAAAAAAAAAAAGAATATATTGACGGAAGAATAGAGAGGA
GGCTTGAAGGAACCAGCAATGAGAAGGCCAGGAAAAGAAAGAGCTGAAAATGGAGAAAGCCCAAGAGTTAGAACAGTTGG
ATACAGGAGAAGAAACAGCGGCTCCACTACAGACCCAGCCCCAGGTTCAATGTCCTCCGAAGAATGAAGTCTTTCCCTGG
TGATGGTCCCCTGCCCTGTCTTTCCAGCATCCACTCTCCCTTGTCCTCCTGGGGGCATATCTCAGTCAGGCAGCGGCTTC
CTGATGATGGTCATTGGGGTGGTTGTCATGTGATGGGTCCCCTCCAGGTTACTAAAGGGTGCATGTCCCCTGCTTGAACA
CTGAAGGGCAGGTGGTGGGCCATGGCCATGGTCCCCAGCTGAGGAGCAGGTGTCCCTGAGAACCCAAACTTCCCAGAGAG
TATGTGAGAACCAACCAATGAAAACAGTCCCATCGCTCTTACCCGGTAAGTAAACAGTCAGAAAATTAGCATGAAAGCAG
TTTAGCATTGGGAGGAAGCTCAGATCTCTAGAGCTGTCTTGTCGCCGCCCAGGATTGACCTGTGTGTAAGTCCCAATAAA
CTCACCTACTCATCAAGCTGGAAAAAAAAAAAAAAAAAAAAAAA
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Primary source |
RefSeq : NM_001136541.1 (GI:211938441)
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Name |
Apolipoprotein L, 1 (APOL1), transcript variant 4
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Type of transcript |
mRNA
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Organism |
Homo sapiens
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Length |
2831 nt
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Map |
22q13.1
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Location |
Chromosome 22 (NC_000022.10) strand : +
36649116...36649264 | 36650982...36651044 | 36653364...36653452 | 36657641...36657767 |
36661196...36663576 |
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Exon(s) |
Start |
End |
Length |
is coding |
Exon 1
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1
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149
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149
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1
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Exon 3b
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150
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212
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63
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1
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Exon 5
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213
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301
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89
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1
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Exon 6
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302
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428
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127
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1
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Exon 7
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429
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2809
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2381
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1
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ID |
Class |
Location |
Mutation |
Length |
is synonymous |
Source |
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Primary source |
NCBI : CCDS46702
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Nucleotide |
APOL1, mRNA isoform 4[NM_001136541.1] : 169...1311
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Length |
1143
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Location |
Chromosome 22 (NC_000022.10) strand : +
36651001...36651044 | 36653364...36653452 | 36657641...36657767 | 36661196...36662078 |
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Start codon |
1
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Translation |
NP_001130013.1 |
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1 |
GACTTTCACT |
TTCCCTTTCG |
AATTCCTCGG |
TATATCTTGG |
GGACTGGAGG |
ACCTGTCTGG |
TTATTATACA |
GACGCATAAC |
|
81 |
TGGAGGTGGG |
ATCCACACAG |
CTCAGAACAG |
CTGGATCTTG |
CTCAGTCTCT |
GCCAGGGGAA |
GATTCCTTGG |
AGGAGGCCCT |
|
161 |
GCAGCGACAT |
GGAGGGAGCT |
GCTTTGCTGA |
GAGTCTCTGT |
CCTCTGCATC |
TGGGTGCAAC |
AAAACGTTCC |
AAGTGGGACA |
|
241 |
GATACTGGAG |
ATCCTCAAAG |
TAAGCCCCTC |
GGTGACTGGG |
CTGCTGGCAC |
CATGGACCCA |
GAGAGCAGTA |
TCTTTATTGA |
|
321 |
GGATGCCATT |
AAGTATTTCA |
AGGAAAAAGT |
GAGCACACAG |
AATCTGCTAC |
TCCTGCTGAC |
TGATAATGAG |
GCCTGGAACG |
|
401 |
GATTCGTGGC |
TGCTGCTGAA |
CTGCCCAGGA |
ATGAGGCAGA |
TGAGCTCCGT |
AAAGCTCTGG |
ACAACCTTGC |
AAGACAAATG |
|
481 |
ATCATGAAAG |
ACAAAAACTG |
GCACGATAAA |
GGCCAGCAGT |
ACAGAAACTG |
GTTTCTGAAA |
GAGTTTCCTC |
GGTTGAAAAG |
|
561 |
TGAGCTTGAG |
GATAACATAA |
GAAGGCTCCG |
TGCCCTTGCA |
GATGGGGTTC |
AGAAGGTCCA |
CAAAGGCACC |
ACCATCGCCA |
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641 |
ATGTGGTGTC |
TGGCTCTCTC |
AGCATTTCCT |
CTGGCATCCT |
GACCCTCGTC |
GGCATGGGTC |
TGGCACCCTT |
CACAGAGGGA |
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721 |
GGCAGCCTTG |
TACTCTTGGA |
ACCTGGGATG |
GAGTTGGGAA |
TCACAGCCGC |
TTTGACCGGG |
ATTACCAGCA |
GTACCATGGA |
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801 |
CTACGGAAAG |
AAGTGGTGGA |
CACAAGCCCA |
AGCCCACGAC |
CTGGTCATCA |
AAAGCCTTGA |
CAAATTGAAG |
GAGGTGAGGG |
|
881 |
AGTTTTTGGG |
TGAGAACATA |
TCCAACTTTC |
TTTCCTTAGC |
TGGCAATACT |
TACCAACTCA |
CACGAGGCAT |
TGGGAAGGAC |
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961 |
ATCCGTGCCC |
TCAGACGAGC |
CAGAGCCAAT |
CTTCAGTCAG |
TACCGCATGC |
CTCAGCCTCA |
CGCCCCCGGG |
TCACTGAGCC |
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1041 |
AATCTCAGCT |
GAAAGCGGTG |
AACAGGTGGA |
GAGGGTTAAT |
GAACCCAGCA |
TCCTGGAAAT |
GAGCAGAGGA |
GTCAAGCTCA |
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1121 |
CGGATGTGGC |
CCCTGTAAGC |
TTCTTTCTTG |
TGCTGGATGT |
AGTCTACCTC |
GTGTACGAAT |
CAAAGCACTT |
ACATGAGGGG |
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1201 |
GCAAAGTCAG |
AGACAGCTGA |
GGAGCTGAAG |
AAGGTGGCTC |
AGGAGCTGGA |
GGAGAAGCTA |
AACATTCTCA |
ACAATAATTA |
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1281 |
TAAGATTCTG |
CAGGCGGACC |
AAGAACTGTG |
ACCACAGGGC |
AGGGCAGCCA |
CCAGGAGAGA |
TATGCCTGGC |
AGGGGCCAGG |
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1361 |
ACAAAATGCA |
AACTTTTTTT |
TTTTTCTGAG |
ACAGAGTCTT |
GCTCTGTCGC |
CAAGTTGGAG |
TGCAATGGTG |
CGATCTCAGC |
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1441 |
TCACTGCAAG |
CTCTGCCTCC |
CGTGTTCAAG |
CGATTCTCCT |
GCCTTGGCCT |
CCCAAGTAGC |
TGGGACTACA |
GGCGCCTACC |
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1521 |
ACCATGCCCA |
GCTAATTTTT |
GTATTTTTAA |
TAGAGATGGG |
GTTTCACCAT |
GTTGGCCAGG |
ATGGTCTCGA |
TCTCCTGACC |
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1601 |
TCTTGATCTG |
CCCACCTTGG |
CCTCCCAAAG |
TGCTGGGATT |
ACAGGCGTGA |
GCCATCGCTT |
TTGACCCAAA |
TGCAAACATT |
|
1681 |
TTATTAGGGG |
GATAAAGAGG |
GTGAGGTAAA |
GTTTATGGAA |
CTGAGTGTTA |
GGGACTTTGG |
CATTTCCATA |
GCTGAGCACA |
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1761 |
GCAGGGGAGG |
GGTTAATGCA |
GATGGCAGTG |
CAGCAAGGAG |
AAGGCAGGAA |
CATTGGAGCC |
TGCAATAAGG |
GAAAAATGGG |
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1841 |
AACTGGAGAG |
TGTGGGGAAT |
GGGAAGAAGC |
AGTTTACTTT |
AGACTAAAGA |
ATATATTGGG |
GGGCCGGGTG |
TAGTGGCTCA |
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1921 |
TGCCTGTAAT |
CCGAGCACTT |
TGGGAGGCCA |
AGGCGGGCGG |
ATCACGAGGT |
CAGGAGATCG |
AGACCATCCT |
GGCTAACACA |
|
2001 |
GTGAAACCCC |
GTCTCTACTA |
AAAATACAAA |
AAATTAGCCG |
GGCATGGTGG |
CGGGCGCCTG |
TAGTTCCAGC |
TAACTGGGCG |
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2081 |
GCTGAGGCAG |
GAGAATGGCG |
TGAACCTGGG |
AGGTGGAGCT |
TGCAGTGAGC |
CGAGATATCG |
CCACTGCACT |
CCAGCCTGGG |
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2161 |
TGACAGAGCG |
AGACTCCATC |
TCAAAAAAAA |
AAAAAAAAAG |
AATATATTGA |
CGGAAGAATA |
GAGAGGAGGC |
TTGAAGGAAC |
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2241 |
CAGCAATGAG |
AAGGCCAGGA |
AAAGAAAGAG |
CTGAAAATGG |
AGAAAGCCCA |
AGAGTTAGAA |
CAGTTGGATA |
CAGGAGAAGA |
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2321 |
AACAGCGGCT |
CCACTACAGA |
CCCAGCCCCA |
GGTTCAATGT |
CCTCCGAAGA |
ATGAAGTCTT |
TCCCTGGTGA |
TGGTCCCCTG |
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2401 |
CCCTGTCTTT |
CCAGCATCCA |
CTCTCCCTTG |
TCCTCCTGGG |
GGCATATCTC |
AGTCAGGCAG |
CGGCTTCCTG |
ATGATGGTCA |
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2481 |
TTGGGGTGGT |
TGTCATGTGA |
TGGGTCCCCT |
CCAGGTTACT |
AAAGGGTGCA |
TGTCCCCTGC |
TTGAACACTG |
AAGGGCAGGT |
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2561 |
GGTGGGCCAT |
GGCCATGGTC |
CCCAGCTGAG |
GAGCAGGTGT |
CCCTGAGAAC |
CCAAACTTCC |
CAGAGAGTAT |
GTGAGAACCA |
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2641 |
ACCAATGAAA |
ACAGTCCCAT |
CGCTCTTACC |
CGGTAAGTAA |
ACAGTCAGAA |
AATTAGCATG |
AAAGCAGTTT |
AGCATTGGGA |
|
2721 |
GGAAGCTCAG |
ATCTCTAGAG |
CTGTCTTGTC |
GCCGCCCAGG |
ATTGACCTGT |
GTGTAAGTCC |
CAATAAACTC |
ACCTACTCAT |
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2801 |
CAAGCTGGAA |
AAAAAAAAAA |
AAAAAAAAAA |
A |
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>gi|211938441|ref|NM_001136541.1|Apolipoprotein L, 1 (APOL1), transcript variant 4
GACTTTCACTTTCCCTTTCGAATTCCTCGGTATATCTTGGGGACTGGAGGACCTGTCTGGTTATTATACAGACGCATAAC
TGGAGGTGGGATCCACACAGCTCAGAACAGCTGGATCTTGCTCAGTCTCTGCCAGGGGAAGATTCCTTGGAGGAGGCCCT
GCAGCGACATGGAGGGAGCTGCTTTGCTGAGAGTCTCTGTCCTCTGCATCTGGGTGCAACAAAACGTTCCAAGTGGGACA
GATACTGGAGATCCTCAAAGTAAGCCCCTCGGTGACTGGGCTGCTGGCACCATGGACCCAGAGAGCAGTATCTTTATTGA
GGATGCCATTAAGTATTTCAAGGAAAAAGTGAGCACACAGAATCTGCTACTCCTGCTGACTGATAATGAGGCCTGGAACG
GATTCGTGGCTGCTGCTGAACTGCCCAGGAATGAGGCAGATGAGCTCCGTAAAGCTCTGGACAACCTTGCAAGACAAATG
ATCATGAAAGACAAAAACTGGCACGATAAAGGCCAGCAGTACAGAAACTGGTTTCTGAAAGAGTTTCCTCGGTTGAAAAG
TGAGCTTGAGGATAACATAAGAAGGCTCCGTGCCCTTGCAGATGGGGTTCAGAAGGTCCACAAAGGCACCACCATCGCCA
ATGTGGTGTCTGGCTCTCTCAGCATTTCCTCTGGCATCCTGACCCTCGTCGGCATGGGTCTGGCACCCTTCACAGAGGGA
GGCAGCCTTGTACTCTTGGAACCTGGGATGGAGTTGGGAATCACAGCCGCTTTGACCGGGATTACCAGCAGTACCATGGA
CTACGGAAAGAAGTGGTGGACACAAGCCCAAGCCCACGACCTGGTCATCAAAAGCCTTGACAAATTGAAGGAGGTGAGGG
AGTTTTTGGGTGAGAACATATCCAACTTTCTTTCCTTAGCTGGCAATACTTACCAACTCACACGAGGCATTGGGAAGGAC
ATCCGTGCCCTCAGACGAGCCAGAGCCAATCTTCAGTCAGTACCGCATGCCTCAGCCTCACGCCCCCGGGTCACTGAGCC
AATCTCAGCTGAAAGCGGTGAACAGGTGGAGAGGGTTAATGAACCCAGCATCCTGGAAATGAGCAGAGGAGTCAAGCTCA
CGGATGTGGCCCCTGTAAGCTTCTTTCTTGTGCTGGATGTAGTCTACCTCGTGTACGAATCAAAGCACTTACATGAGGGG
GCAAAGTCAGAGACAGCTGAGGAGCTGAAGAAGGTGGCTCAGGAGCTGGAGGAGAAGCTAAACATTCTCAACAATAATTA
TAAGATTCTGCAGGCGGACCAAGAACTGTGACCACAGGGCAGGGCAGCCACCAGGAGAGATATGCCTGGCAGGGGCCAGG
ACAAAATGCAAACTTTTTTTTTTTTCTGAGACAGAGTCTTGCTCTGTCGCCAAGTTGGAGTGCAATGGTGCGATCTCAGC
TCACTGCAAGCTCTGCCTCCCGTGTTCAAGCGATTCTCCTGCCTTGGCCTCCCAAGTAGCTGGGACTACAGGCGCCTACC
ACCATGCCCAGCTAATTTTTGTATTTTTAATAGAGATGGGGTTTCACCATGTTGGCCAGGATGGTCTCGATCTCCTGACC
TCTTGATCTGCCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCATCGCTTTTGACCCAAATGCAAACATT
TTATTAGGGGGATAAAGAGGGTGAGGTAAAGTTTATGGAACTGAGTGTTAGGGACTTTGGCATTTCCATAGCTGAGCACA
GCAGGGGAGGGGTTAATGCAGATGGCAGTGCAGCAAGGAGAAGGCAGGAACATTGGAGCCTGCAATAAGGGAAAAATGGG
AACTGGAGAGTGTGGGGAATGGGAAGAAGCAGTTTACTTTAGACTAAAGAATATATTGGGGGGCCGGGTGTAGTGGCTCA
TGCCTGTAATCCGAGCACTTTGGGAGGCCAAGGCGGGCGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACACA
GTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCGGGCATGGTGGCGGGCGCCTGTAGTTCCAGCTAACTGGGCG
GCTGAGGCAGGAGAATGGCGTGAACCTGGGAGGTGGAGCTTGCAGTGAGCCGAGATATCGCCACTGCACTCCAGCCTGGG
TGACAGAGCGAGACTCCATCTCAAAAAAAAAAAAAAAAAGAATATATTGACGGAAGAATAGAGAGGAGGCTTGAAGGAAC
CAGCAATGAGAAGGCCAGGAAAAGAAAGAGCTGAAAATGGAGAAAGCCCAAGAGTTAGAACAGTTGGATACAGGAGAAGA
AACAGCGGCTCCACTACAGACCCAGCCCCAGGTTCAATGTCCTCCGAAGAATGAAGTCTTTCCCTGGTGATGGTCCCCTG
CCCTGTCTTTCCAGCATCCACTCTCCCTTGTCCTCCTGGGGGCATATCTCAGTCAGGCAGCGGCTTCCTGATGATGGTCA
TTGGGGTGGTTGTCATGTGATGGGTCCCCTCCAGGTTACTAAAGGGTGCATGTCCCCTGCTTGAACACTGAAGGGCAGGT
GGTGGGCCATGGCCATGGTCCCCAGCTGAGGAGCAGGTGTCCCTGAGAACCCAAACTTCCCAGAGAGTATGTGAGAACCA
ACCAATGAAAACAGTCCCATCGCTCTTACCCGGTAAGTAAACAGTCAGAAAATTAGCATGAAAGCAGTTTAGCATTGGGA
GGAAGCTCAGATCTCTAGAGCTGTCTTGTCGCCGCCCAGGATTGACCTGTGTGTAAGTCCCAATAAACTCACCTACTCAT
CAAGCTGGAAAAAAAAAAAAAAAAAAAAAAA
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Exon number |
2
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Length |
154 nt
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Location |
Chromosome 22 (NC_000022.10) : 36649883...36650036 (+)
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Is part of |
APOL1, mRNA isoform 2
(NM_145343.2)
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Sequence |
Show
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ACTTCTGGGGTGATGGAGAAGAAACAGGCTGTGCTGTGTCCCTAATGGGAAACGTGGCTGAGACAGGGGAGTGAGAAGGG
TGCGTTGCAGAATGGTGCCTGTGGCATGATGCCAGCTTTGCAATCATGAGATTCAAAAGCCACACTGTGGAATT
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Exon number |
3a
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Length |
102 nt
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Location |
Chromosome 22 (NC_000022.10) : 36650943...36651044 (+)
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Is part of |
APOL1, mRNA isoform 3
(NM_001136540.1)
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Sequence |
Show
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GAGGAGCACACTGTCTCAACCCCTCTTTTCCTGCTCAAGGAGGAGGCCCTGCAGCGACATGGAGGGAGCTGCTTTGCTGA
GAGTCTCTGTCCTCTGCATCTG
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Exon number |
7
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Length |
2381 nt
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Location |
Chromosome 22 (NC_000022.10) : 36661196...36663576 (+)
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Is part of |
APOL1, mRNA isoform 3
(NM_001136540.1)
APOL1, mRNA isoform 4
(NM_001136541.1)
APOL1, mRNA isoform 2
(NM_145343.2)
APOL1, mRNA isoform 1
(NM_003661.3)
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Sequence |
Show
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GAATGAGGCAGATGAGCTCCGTAAAGCTCTGGACAACCTTGCAAGACAAATGATCATGAAAGACAAAAACTGGCACGATA
AAGGCCAGCAGTACAGAAACTGGTTTCTGAAAGAGTTTCCTCGGTTGAAAAGTGAGCTTGAGGATAACATAAGAAGGCTC
CGTGCCCTTGCAGATGGGGTTCAGAAGGTCCACAAAGGCACCACCATCGCCAATGTGGTGTCTGGCTCTCTCAGCATTTC
CTCTGGCATCCTGACCCTCGTCGGCATGGGTCTGGCACCCTTCACAGAGGGAGGCAGCCTTGTACTCTTGGAACCTGGGA
TGGAGTTGGGAATCACAGCCGCTTTGACCGGGATTACCAGCAGTACCATGGACTACGGAAAGAAGTGGTGGACACAAGCC
CAAGCCCACGACCTGGTCATCAAAAGCCTTGACAAATTGAAGGAGGTGAGGGAGTTTTTGGGTGAGAACATATCCAACTT
TCTTTCCTTAGCTGGCAATACTTACCAACTCACACGAGGCATTGGGAAGGACATCCGTGCCCTCAGACGAGCCAGAGCCA
ATCTTCAGTCAGTACCGCATGCCTCAGCCTCACGCCCCCGGGTCACTGAGCCAATCTCAGCTGAAAGCGGTGAACAGGTG
GAGAGGGTTAATGAACCCAGCATCCTGGAAATGAGCAGAGGAGTCAAGCTCACGGATGTGGCCCCTGTAAGCTTCTTTCT
TGTGCTGGATGTAGTCTACCTCGTGTACGAATCAAAGCACTTACATGAGGGGGCAAAGTCAGAGACAGCTGAGGAGCTGA
AGAAGGTGGCTCAGGAGCTGGAGGAGAAGCTAAACATTCTCAACAATAATTATAAGATTCTGCAGGCGGACCAAGAACTG
TGACCACAGGGCAGGGCAGCCACCAGGAGAGATATGCCTGGCAGGGGCCAGGACAAAATGCAAACTTTTTTTTTTTTCTG
AGACAGAGTCTTGCTCTGTCGCCAAGTTGGAGTGCAATGGTGCGATCTCAGCTCACTGCAAGCTCTGCCTCCCGTGTTCA
AGCGATTCTCCTGCCTTGGCCTCCCAAGTAGCTGGGACTACAGGCGCCTACCACCATGCCCAGCTAATTTTTGTATTTTT
AATAGAGATGGGGTTTCACCATGTTGGCCAGGATGGTCTCGATCTCCTGACCTCTTGATCTGCCCACCTTGGCCTCCCAA
AGTGCTGGGATTACAGGCGTGAGCCATCGCTTTTGACCCAAATGCAAACATTTTATTAGGGGGATAAAGAGGGTGAGGTA
AAGTTTATGGAACTGAGTGTTAGGGACTTTGGCATTTCCATAGCTGAGCACAGCAGGGGAGGGGTTAATGCAGATGGCAG
TGCAGCAAGGAGAAGGCAGGAACATTGGAGCCTGCAATAAGGGAAAAATGGGAACTGGAGAGTGTGGGGAATGGGAAGAA
GCAGTTTACTTTAGACTAAAGAATATATTGGGGGGCCGGGTGTAGTGGCTCATGCCTGTAATCCGAGCACTTTGGGAGGC
CAAGGCGGGCGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACACAGTGAAACCCCGTCTCTACTAAAAATACA
AAAAATTAGCCGGGCATGGTGGCGGGCGCCTGTAGTTCCAGCTAACTGGGCGGCTGAGGCAGGAGAATGGCGTGAACCTG
GGAGGTGGAGCTTGCAGTGAGCCGAGATATCGCCACTGCACTCCAGCCTGGGTGACAGAGCGAGACTCCATCTCAAAAAA
AAAAAAAAAAAGAATATATTGACGGAAGAATAGAGAGGAGGCTTGAAGGAACCAGCAATGAGAAGGCCAGGAAAAGAAAG
AGCTGAAAATGGAGAAAGCCCAAGAGTTAGAACAGTTGGATACAGGAGAAGAAACAGCGGCTCCACTACAGACCCAGCCC
CAGGTTCAATGTCCTCCGAAGAATGAAGTCTTTCCCTGGTGATGGTCCCCTGCCCTGTCTTTCCAGCATCCACTCTCCCT
TGTCCTCCTGGGGGCATATCTCAGTCAGGCAGCGGCTTCCTGATGATGGTCATTGGGGTGGTTGTCATGTGATGGGTCCC
CTCCAGGTTACTAAAGGGTGCATGTCCCCTGCTTGAACACTGAAGGGCAGGTGGTGGGCCATGGCCATGGTCCCCAGCTG
AGGAGCAGGTGTCCCTGAGAACCCAAACTTCCCAGAGAGTATGTGAGAACCAACCAATGAAAACAGTCCCATCGCTCTTA
CCCGGTAAGTAAACAGTCAGAAAATTAGCATGAAAGCAGTTTAGCATTGGGAGGAAGCTCAGATCTCTAGAGCTGTCTTG
TCGCCGCCCAGGATTGACCTGTGTGTAAGTCCCAATAAACTCACCTACTCATCAAGCTGGA
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Primary source |
Uniprot : O14791
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Name |
Apolipoprotein L1
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Alternative name(s) |
Apolipoprotein L Apolipoprotein L-I
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Synonym(s) |
Apo-L ApoL ApoL-I
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Organism |
Homo sapiens
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Length |
398 aa
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Protein existence |
---
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General annotation (Comments)
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top
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Function
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May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver.
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Ptm
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Phosphorylation sites are present in the extracelllular medium.
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Similarity
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Belongs to the apolipoprotein L family.
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Subcellular location
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Secreted.
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Subunit
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In plasma, interacts with APOA1 and mainly associated with large high density lipoprotein particles.
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Tissue specificity
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Plasma. Found on APOA-I-containing high density lipoprotein (HDL3). Expressed in pancreas, lung, prostate, liver, placenta and spleen.
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Biological process
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chloride transport [GO:0006821]
lipid transport [GO:0006869]
cholesterol metabolic process [GO:0008203]
cytolysis [GO:0019835]
killing of cells of another organism [GO:0031640]
lipoprotein metabolic process [GO:0042157]
innate immune response [GO:0045087]
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Cellular component
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intrinsic to membrane [GO:0031224]
high-density lipoprotein particle [GO:0034364]
very-low-density lipoprotein particle [GO:0034361]
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Molecular function
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chloride channel activity [GO:0005254]
protein binding [GO:0005515]
lipid binding [GO:0008289]
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With
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Uniprot accession
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IntAct
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Alternative product(s)
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Uniprot Identifier
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Difference(s) with the 'canonical' sequence
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Notes
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Sequences
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Isoform 1
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O14791-1
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'Canonical' sequence
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Get Fasta
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Isoform 2
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O14791-2
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1-1 : M -> MRFKSHTVELRRPCSDM
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Get Fasta
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Feature key |
Position
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Length
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Description
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Feature identifier
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Molecule processing |
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Signal
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1 - 27
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27
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O14791-SIGNAL-1
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Natural variations |
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Natural variant site
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150 - 150
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1
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E -> K (in dbSNP:rs2239785)
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VAR_011383
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Natural variant site
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188 - 188
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1
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I -> T (in a breast cancer sample; somatic mutation)
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VAR_036568
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Natural variant site
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228 - 228
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1
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M -> I (in dbSNP:rs136175)
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VAR_011384
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Natural variant site
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255 - 255
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1
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R -> K (in dbSNP:rs136176)
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VAR_011385
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Natural variant site
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337 - 337
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1
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D -> N (in dbSNP:rs16996616)
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VAR_046641
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Natural variant site
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384 - 384
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1
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I -> M (in dbSNP:rs60910145)
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VAR_061995
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Alternative sequence
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1 - 1
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1
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M -> MRFKSHTVELRRPCSDM
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VSP_000292
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Amino acid modifications |
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Glycosylation
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261 - 261
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1
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N-linked (GlcNAc...)
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O14791-CARBOHYD-261
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Modified residue
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311 - 311
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1
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Phosphoserine
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O14791-MOD_RES-311
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Modified residue
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314 - 314
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1
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Phosphoserine
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O14791-MOD_RES-314
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1 |
MEGAALLRVS |
VLCIWMSALF |
LGVGVRAEEA |
GARVQQNVPS |
GTDTGDPQSK |
PLGDWAAGTM |
DPESSIFIED |
AIKYFKEKVS |
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TQNLLLLLTD |
NEAWNGFVAA |
AELPRNEADE |
LRKALDNLAR |
QMIMKDKNWH |
DKGQQYRNWF |
LKEFPRLKSE |
LEDNIRRLRA |
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161 |
LADGVQKVHK |
GTTIANVVSG |
SLSISSGILT |
LVGMGLAPFT |
EGGSLVLLEP |
GMELGITAAL |
TGITSSTMDY |
GKKWWTQAQA |
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241 |
HDLVIKSLDK |
LKEVREFLGE |
NISNFLSLAG |
NTYQLTRGIG |
KDIRALRRAR |
ANLQSVPHAS |
ASRPRVTEPI |
SAESGEQVER |
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321 |
VNEPSILEMS |
RGVKLTDVAP |
VSFFLVLDVV |
YLVYESKHLH |
EGAKSETAEE |
LKKVAQELEE |
KLNILNNNYK |
ILQADQEL |
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>sp|O14791|APOL1_human Apolipoprotein L1
MEGAALLRVSVLCIWMSALFLGVGVRAEEAGARVQQNVPSGTDTGDPQSKPLGDWAAGTMDPESSIFIEDAIKYFKEKVS
TQNLLLLLTDNEAWNGFVAAAELPRNEADELRKALDNLARQMIMKDKNWHDKGQQYRNWFLKEFPRLKSELEDNIRRLRA
LADGVQKVHKGTTIANVVSGSLSISSGILTLVGMGLAPFTEGGSLVLLEPGMELGITAALTGITSSTMDYGKKWWTQAQA
HDLVIKSLDKLKEVREFLGENISNFLSLAGNTYQLTRGIGKDIRALRRARANLQSVPHASASRPRVTEPISAESGEQVER
VNEPSILEMSRGVKLTDVAPVSFFLVLDVVYLVYESKHLHEGAKSETAEELKKVAQELEEKLNILNNNYKILQADQEL
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Primary source |
Uniprot : Q2KHQ6
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Name |
APOL1 protein [submitted name]
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Alternative name(s) |
Apolipoprotein L, 1 [submitted name]
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Synonym(s) |
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Organism |
Homo sapiens
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Length |
398 aa
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Protein existence |
---
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General annotation (Comments)
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top
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Biological process
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lipid transport [GO:0006869]
lipoprotein metabolic process [GO:0042157]
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Cellular component
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extracellular region [GO:0005576]
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Molecular function
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lipid binding [GO:0008289]
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With
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Uniprot accession
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IntAct
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Alternative product(s)
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top
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Feature key |
Position
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Length
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Description
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Feature identifier
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1 |
MEGAALLRVS |
VLCIWMSALF |
LGVGVRAEEA |
GARVQQNVPS |
GTDTGDPQSK |
PLGDWAAGTM |
DPESSIFIED |
AIKYFKEKVS |
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81 |
TQNLLLLLTD |
NEAWNGFVAA |
AELPRNEADE |
LRKALDNLAR |
QMIMKDKNWH |
DKGQQYRNWF |
LKEFPRLKSK |
LEDNIRRLRA |
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161 |
LADGVQKVHK |
GTTIANVVSG |
SLSISSGILT |
LVGMGLAPFT |
EGGSLVLLEP |
GMELGITAAL |
TGITSSTIDY |
GKKWWTQAQA |
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241 |
HDLVIKSLDK |
LKEVKEFLGE |
NISNFLSLAG |
NTYQLTRGIG |
KDIRALRRAR |
ANLQSVPHAS |
ASRPRVTEPI |
SAESGEQVER |
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321 |
VNEPSILEMS |
RGVKLTDVAP |
VSFFLVLDVV |
YLVYESKHLH |
EGAKSETAEE |
LKKVAQELEE |
KLNILNNNYK |
ILQADQEL |
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>sp|Q2KHQ6|Q2KHQ6_human APOL1 protein [submitted name]
MEGAALLRVSVLCIWMSALFLGVGVRAEEAGARVQQNVPSGTDTGDPQSKPLGDWAAGTMDPESSIFIEDAIKYFKEKVS
TQNLLLLLTDNEAWNGFVAAAELPRNEADELRKALDNLARQMIMKDKNWHDKGQQYRNWFLKEFPRLKSKLEDNIRRLRA
LADGVQKVHKGTTIANVVSGSLSISSGILTLVGMGLAPFTEGGSLVLLEPGMELGITAALTGITSSTIDYGKKWWTQAQA
HDLVIKSLDKLKEVKEFLGENISNFLSLAGNTYQLTRGIGKDIRALRRARANLQSVPHASASRPRVTEPISAESGEQVER
VNEPSILEMSRGVKLTDVAPVSFFLVLDVVYLVYESKHLHEGAKSETAEELKKVAQELEEKLNILNNNYKILQADQEL
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Primary source |
Uniprot : B1AH95
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Name |
Apolipoprotein L, 1 [submitted name]
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Alternative name(s) |
cDNA FLJ59906, moderately similar to Apolipoprotein-L1 [submitted name]
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Synonym(s) |
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Organism |
Homo sapiens
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Length |
141 aa
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Protein existence |
---
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General annotation (Comments)
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top
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Biological process
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lipid transport [GO:0006869]
lipoprotein metabolic process [GO:0042157]
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Cellular component
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extracellular region [GO:0005576]
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Molecular function
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lipid binding [GO:0008289]
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With
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Uniprot accession
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IntAct
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Alternative product(s)
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top
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Feature key |
Position
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Length
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Description
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Feature identifier
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1 |
MEGAALLRVS |
VLCIWMSALF |
LGVGVRAEEA |
GARVQQNVPS |
GTDTGDPQSK |
PLGDWAAGTM |
DPGPAGSRGD |
SGEPCTLRPA |
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81 |
CRGQRQHGGA |
SRISAEGPAP |
MPRRRTPSTA |
HLRVPKTSRR |
NLLCMRAVSL |
LRMPLSISRK |
K |
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>sp|B1AH95|B1AH95_human Apolipoprotein L, 1 [submitted name]
MEGAALLRVSVLCIWMSALFLGVGVRAEEAGARVQQNVPSGTDTGDPQSKPLGDWAAGTMDPGPAGSRGDSGEPCTLRPA
CRGQRQHGGASRISAEGPAPMPRRRTPSTAHLRVPKTSRRNLLCMRAVSLLRMPLSISRKK
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