(DIRAS3) DIRAS family, GTP-binding RAS-like 3 [Homo sapiens]
Gene
Transcript(s)
Exon(s)
Protein(s)
Gene
 Accession  967
 Official symbol  DIRAS3
 Official name  DIRAS family, GTP-binding RAS-like 3
 Gene type  gene with protein product
 Organism  Homo sapiens
 Location  Chromosome 1 (NC_000001.10) :  68511644...68516459  (-)
 Map  1p31
 Length  4816  nt
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Alternative name(s) and Synynom(s) top
Synonyms NOEY2; ARHI
Alternative name(s) dIRAS family, GTP-binding RAS-like 3; ras homolog gene family, member I
External Links top
Ensembl ENSG00000162595
Entrez 9077
HGNC 687
HPRD 05547
Comment top
Summary This gene is a member of the ras superfamily, and is expressed in normal ovarian and breast epithelial cells but not in ovarian and breast cancers. It is a maternally imprinted gene and its expression is associated with growth suppression. Thus, this gene appears to be a putative tumor suppressor gene whose function is abrogated in ovarian and breast cancers. [provided by RefSeq].
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Related Articles in PubMed
Genomic Context top
Go to ensembl   www.ensembl.org
Sequence top
FASTA
1  CTCTGCGTTG GGCCAGCCCC TCACAGCTGG TTTCTTACCA CGTATTGCGC AAGCGGAATC TATGCCTGTT ACCCACACTC
81  CCTGCGCCCC CGCACCCCGC TCCTGTGCGC AAGTCGGAAT ATAAAACCGC GGAGGAGTGA GCTCTTGGGG TGTCCAGTTG
161  GTTGCCGCGG CAGTCTCTCC GAGCAGCGCA TTTGTCTTCT AGGCTGCTTG GTTCGTGCCT CCGAGAAAGG TAAGTCTTTC
241  TTTCGCTTTT TTAGGGGTAC TTGAAAACAA CAAGTGTCAG ACAAAGCAGC AGATGCTGTT GCGCAGTAGA AGTTTATGGG
321  CGAGTTGTCC CTGAAACTGG AACCAGGTCT TTCTTGGCGC GATTACGCAA GAACCACCCG CAGCCCTGCG GGCTCCTGGC
401  AGGTCCTGCA ACTGCACTTT GGATAGTCCC GTTGGGAAGC TAGCACTTTT TAATATAGAA GAACGAGGTT TGATAAGTGT
481  GCGAGCTTAA AGGTTGACAC AGTGTCCACT ATTACAGCTG CGTAGGTAGC TAGTGTTCAG GAAGTAATAG TGGAGTCATG
561  TAGTGTGAAA GTAAGATTGA AATGGGCGAG GAGGGTAGCA GCCGCCACAG CCACCAGAGA GAAACCTGAC CTTGCAGGTG
641  CGTGGTGATG TCCATGAGCC AGGCTGGTGC CGCAACAGCA GCGGCGGGAC CTTGAGCTCC GCACGGCCGC TGGGTTTGGA
721  CGCCCTCTGG TTCCTGGAAA CTTTCACCTC CCCCTCAGCC TGAGGCCAGG TGGCCTGGGA AGGTGGAAGG AGTGTGGAGG
801  GGAGTGGGGG GGGGGGTCCA CTGCCTGAGA ATGAGAATTC TCTTCACATC TGGAAACTTC AGTTATCACG TGTGTCCTTT
881  ACCAATTTTT TTTCTTTTAT TTTCTTTTTG ATAGAGACGG CGGTCTCCCT ATGTTACCCA GGCTAGTCTT GAACTCCTGT
961  GCTTAAGCGA TCCTCCCACC TTGACTTCCC AAAGTGCTGG AATTACAGGC ATGAGCCAAT GCGCCCGGCT GCTTTACCAA
1041  TTTTCTATGA ATGAATTTGT ACATACATCC CCTAGAGCAG GAAGTAATGT AAAACAGAAT AATTAGTAAT GCACATTTCC
1121  TAATGTGGGA TGTTGGTGGC CAAGAGATAT TTGGTCTTTA CTGGAACTCT TGATACTAAC ATGGAGTTTA TAATAGTTGT
1201  GGAGAGTGCA GACAAGGCTA GGATTTCTGT GACTAGAGAA CTCTTAGTGC GTGAAGACCT AAGGAAAGCT GGATTGTTGA
1281  TTTTTGTTAA TAAATAAGAT GTGAAAGATT GCATCACTGT AGCAGAAATC TCCTAGTTTT TTAAGCTAAA TTCTATTAAA
1361  GGTCATCATT GCTAAAGGAA TTGTGCCCAG GATTTGGATA GCTGATGTCA TTACTTAATA TTAGATGATA TCAACTAACC
1441  ACATCTCATA GACTGGAATA AAGTGCTAGA TTTTACCTGA AAGCTGCAAA AATGAATGGT TTAGATATAT GTATGTATTT
1521  ATTTTATATC AATTTCAAAT ATTTACTGTA TTAACCTCCC TGGCCCCCTT TAATCAAGAA TATAAAATCA TCTACTTAAA
1601  TTTTGCCACT TAAGTTTAGA ACACTCTTAG AATCACACTA TCTTAAAGAA GCCAGACTAG AATTAGAAGC AAGTTAAGTC
1681  TGAAGATATA ACAACCAGCA ACAACATTTT TTTTTTTCAA ATGAAAACTC TAATATGGGG TGGGTATGTT GTGTCACACC
1761  TGTAATCCCA ACACTTTGGG AGGCTGATGC AGGAGGATCA CTTGAACACA GGAGTTCAAG ACCAGCCTGG ACAACATAGC
1841  AAAACCCTGT CCCTACAAAA AATAAGAAAA TTAGCTGGGC ATGGTGTCAC ATGCCTGTAG TCCCAGCTAC TCGGGAGGCT
1921  GAGGTGAGAG GATTGATTGA TCCCAGGAGG TTGAGGCTGC AGTGAGTCAT GATCGCATGA CTGCACTCCA ACCTGAGGGA
2001  CAGAGCAAGA CCCTGACTCA AAAAAAAAAA ACAAAAAAAA AAAAACCACC ACCAAAACTC TAATATGGAC ATATTACTCT
2081  CTCATGGGAC TTGCACATTC TAAAAAGGGT CCTTTTCCCC AGTACTGGGA GAGTATGTGT TCAACTACGC AGCCAGCAAG
2161  ACAGGCTAGT TTATATAGGG AGTGTGCTAT TCACAAAAAG CCTCTCTTCT CTTTCTGGTA TTGTACATGA CACAATCATA
2241  GCTGTACCTG AAGAGAAGTG CATTTTAAGG ACCATCATCA CCTAGAAACA TGTATAAATT TCTATACCTA GTGCCACAGG
2321  AATGACATTG CCTTGTACTA TTCCTACCTC TGTCCAGAGG CCAGCTATGT GGTCTGTCTG CATGGTGCCT AGAACTTTTT
2401  CCATCTGACC TAGGATGCTT CTGAAGCAGT CCCCCTGGGC AGCTGTCTGG TATTTAGGAT ATACCTGTGA GAAAAGTTTC
2481  TTACAAACCT AATCTACTAT GTTTATTCCT GAACTCAAAA AGTTCATTGA CTGTTCAAAT CCTGAAATTT TCTCTATTTC
2561  CATAAGGCTG AATTAAAAGT ACTTTGTTAA AGGTAGTAGC CATGGCAAAA GAAAAACCAC TGTTCTGTAG AAAAACTCAT
2641  TCAATATTTA CAATCTTTTC TAATCAGAGA TTAGATCCTG AAGAGAAAGG TTCATATATA TATATATATA TATATATATA
2721  TATATATTTT TTTTTTTTTT TTTTTTTTTT TTTTTTTACT CCACTGTCAT TGTGACTAAG GATTCATGAA CTAAGACCCC
2801  TCCCTCAGCT CTTGGTGGCA CATGGTGACA GCATGCTCAG AGCAAAGGTG CTCCCCATGC CTCTTCTGGG GCTGCACTGA
2881  CTGCAGGTAC CTCCCCTCTC TACATCCCAC ACCACTGATA CCAAAAACCC CCTCCTTTCT CCTGTACTGA TGACTCTGTA
2961  GCTTTAACCA GGGCGGCGGT GTCACTCTAA ATGTCACCTT GGCATTCAGC CCCATAGAGT GGGGAAAATT CCCTCACCTG
3041  TTTCTCTTTG ACTGTTCAGT CCTCTTCAAT TAAAATCTTA ATTTTACAAG CGAGGAAATG AGAGTGTTTC TTGTAGGGGT
3121  GTAGTGAGAA TTTAATAAAA CAGTTTAAGG AAAGAAAACA AAAGGTAGTA TTGCTGCACT TTCTAGATGG TAAAAAGCAA
3201  ACCACCATGT CTGTTTAATA TATATCACCT GCTGGTCCCT CGGTCTAGCA GGCTGAACTG TGTGCCTGGG AATTTTCTTC
3281  TCGCTGTGTG CACCCCTTTA CGTCACAGGG TGGACTCTCT TCAGAGTCCT AGTGGAGCAG CTGGCCAGGC TGACATGATC
3361  TGACAACATT GTAGGTTACC ACTACCATCT CTCACCGTCT CACTTTCTTC CTAGGGGTCT CCTGCTGCCA GCTAAGTGTG
3441  GGAGAACTTG TGCACGTATC TCCCCTCCGA ATCCCAACGA TGGGTAACGC CAGCTTTGGC TCCAAGGAAC AGAAGCTGCT
3521  GAAGCGGTTG CGGCTTCTGC CCGCCCTGCT TATCCTCCGC GCCTTCAAGC CCCACAGGAA GATCAGAGAT TACCGCGTCG
3601  TGGTAGTCGG CACCGCTGGT GTGGGGAAAA GTACGCTGCT GCACAAGTGG GCGAGCGGCA ACTTCCGTCA TGAGTACCTG
3681  CCGACCATTG AAAATACCTA CTGCCAGTTG CTGGGCTGCA GCCACGGTGT GCTTTCCCTG CACATCACCG ACAGCAAGAG
3761  TGGCGACGGC AACCGCGCTC TGCAGCGCCA CGTTATAGCC CGGGGCCACG CCTTCGTCCT GGTCTACTCA GTCACCAAGA
3841  AGGAAACCCT GGAAGAGCTG AAGGCCTTCT ATGAGCTGAT CTGCAAGATC AAAGGTAACA ACCTGCATAA GTTCCCCATC
3921  GTGCTGGTGG GCAATAAAAG TGATGACACC CACCGGGAGG TGGCCCTGAA TGATGGTGCC ACCTGTGCGA TGGAGTGGAA
4001  TTGCGCCTTC ATGGAGATTT CAGCCAAGAC CGATGTGAAT GTGCAGGAGC TGTTCCACAT GCTGCTGAAT TACAAGAAAA
4081  AGCCCACCAC CGGCCTCCAG GAGCCCGAGA AGAAATCCCA GATGCCCAAC ACCACTGAGA AGCTGCTTGA CAAGTGCATA
4161  ATCATGTGAG CCCTGGGCCT TAAGAGCCAG CTCTTCCTAT CCTGTAGCGT GTAGAAAACG TGGACTCATT TCACTATGTT
4241  ACATGTACAT GGTTGATTTT GTGCTGTTGT TTGGACTGTA ACATCCATGT TGTCAATACG TATACCTTGT AAGTGGATAA
4321  CTTTTCTTTT TCCCAGGCCA GAGAATTCAA ATTGTTAAAA CATTGGCATT TGAAGAGGAG AACAAAATGT AGCATGATGT
4401  ATTTAAAGTA AGGCCTTTAG TAATGAATGT AATGAGAGAA AATGTTTTGA AAAGAACAAA ACATCAAAAT GAATAGAAAG
4481  AAAAATTGGA AGGCGTCCTT TTGGTAACCC GATTATTGTG TATTACCTTT AAATATTTCA CATCCTGTAA GTGCTTAATC
4561  ATATCTTTTA ATTGTGTATT TAAGAAAAGT GTTTTCACAA CAAAAGCTTT TGATAAATTG CTGCGTGACA TATACTAAAT
4641  AAAAAAATGA ATATGTTGAT CATTAGGGGT GTGGGAGCAG AGAAAATTGT GAAAGTGACT CTCACTAAAG ATGTTAGTAG
4721  TTTCTCATGT CATTTAAAAA TGTTTGAGTA TTCTGCATAG CAGTTTGTAA AAGTGTAACA GCTTATTGAC TTAATAAAGC
4801  TTTTCCTGCA TGCAAT
>ref|Gene_ID:9077|DIRAS3|NC_000001.10:68511644...68516459 (-)
CTCTGCGTTGGGCCAGCCCCTCACAGCTGGTTTCTTACCACGTATTGCGCAAGCGGAATCTATGCCTGTTACCCACACTC
CCTGCGCCCCCGCACCCCGCTCCTGTGCGCAAGTCGGAATATAAAACCGCGGAGGAGTGAGCTCTTGGGGTGTCCAGTTG
GTTGCCGCGGCAGTCTCTCCGAGCAGCGCATTTGTCTTCTAGGCTGCTTGGTTCGTGCCTCCGAGAAAGGTAAGTCTTTC
TTTCGCTTTTTTAGGGGTACTTGAAAACAACAAGTGTCAGACAAAGCAGCAGATGCTGTTGCGCAGTAGAAGTTTATGGG
CGAGTTGTCCCTGAAACTGGAACCAGGTCTTTCTTGGCGCGATTACGCAAGAACCACCCGCAGCCCTGCGGGCTCCTGGC
AGGTCCTGCAACTGCACTTTGGATAGTCCCGTTGGGAAGCTAGCACTTTTTAATATAGAAGAACGAGGTTTGATAAGTGT
GCGAGCTTAAAGGTTGACACAGTGTCCACTATTACAGCTGCGTAGGTAGCTAGTGTTCAGGAAGTAATAGTGGAGTCATG
TAGTGTGAAAGTAAGATTGAAATGGGCGAGGAGGGTAGCAGCCGCCACAGCCACCAGAGAGAAACCTGACCTTGCAGGTG
CGTGGTGATGTCCATGAGCCAGGCTGGTGCCGCAACAGCAGCGGCGGGACCTTGAGCTCCGCACGGCCGCTGGGTTTGGA
CGCCCTCTGGTTCCTGGAAACTTTCACCTCCCCCTCAGCCTGAGGCCAGGTGGCCTGGGAAGGTGGAAGGAGTGTGGAGG
GGAGTGGGGGGGGGGGTCCACTGCCTGAGAATGAGAATTCTCTTCACATCTGGAAACTTCAGTTATCACGTGTGTCCTTT
ACCAATTTTTTTTCTTTTATTTTCTTTTTGATAGAGACGGCGGTCTCCCTATGTTACCCAGGCTAGTCTTGAACTCCTGT
GCTTAAGCGATCCTCCCACCTTGACTTCCCAAAGTGCTGGAATTACAGGCATGAGCCAATGCGCCCGGCTGCTTTACCAA
TTTTCTATGAATGAATTTGTACATACATCCCCTAGAGCAGGAAGTAATGTAAAACAGAATAATTAGTAATGCACATTTCC
TAATGTGGGATGTTGGTGGCCAAGAGATATTTGGTCTTTACTGGAACTCTTGATACTAACATGGAGTTTATAATAGTTGT
GGAGAGTGCAGACAAGGCTAGGATTTCTGTGACTAGAGAACTCTTAGTGCGTGAAGACCTAAGGAAAGCTGGATTGTTGA
TTTTTGTTAATAAATAAGATGTGAAAGATTGCATCACTGTAGCAGAAATCTCCTAGTTTTTTAAGCTAAATTCTATTAAA
GGTCATCATTGCTAAAGGAATTGTGCCCAGGATTTGGATAGCTGATGTCATTACTTAATATTAGATGATATCAACTAACC
ACATCTCATAGACTGGAATAAAGTGCTAGATTTTACCTGAAAGCTGCAAAAATGAATGGTTTAGATATATGTATGTATTT
ATTTTATATCAATTTCAAATATTTACTGTATTAACCTCCCTGGCCCCCTTTAATCAAGAATATAAAATCATCTACTTAAA
TTTTGCCACTTAAGTTTAGAACACTCTTAGAATCACACTATCTTAAAGAAGCCAGACTAGAATTAGAAGCAAGTTAAGTC
TGAAGATATAACAACCAGCAACAACATTTTTTTTTTTCAAATGAAAACTCTAATATGGGGTGGGTATGTTGTGTCACACC
TGTAATCCCAACACTTTGGGAGGCTGATGCAGGAGGATCACTTGAACACAGGAGTTCAAGACCAGCCTGGACAACATAGC
AAAACCCTGTCCCTACAAAAAATAAGAAAATTAGCTGGGCATGGTGTCACATGCCTGTAGTCCCAGCTACTCGGGAGGCT
GAGGTGAGAGGATTGATTGATCCCAGGAGGTTGAGGCTGCAGTGAGTCATGATCGCATGACTGCACTCCAACCTGAGGGA
CAGAGCAAGACCCTGACTCAAAAAAAAAAAACAAAAAAAAAAAAACCACCACCAAAACTCTAATATGGACATATTACTCT
CTCATGGGACTTGCACATTCTAAAAAGGGTCCTTTTCCCCAGTACTGGGAGAGTATGTGTTCAACTACGCAGCCAGCAAG
ACAGGCTAGTTTATATAGGGAGTGTGCTATTCACAAAAAGCCTCTCTTCTCTTTCTGGTATTGTACATGACACAATCATA
GCTGTACCTGAAGAGAAGTGCATTTTAAGGACCATCATCACCTAGAAACATGTATAAATTTCTATACCTAGTGCCACAGG
AATGACATTGCCTTGTACTATTCCTACCTCTGTCCAGAGGCCAGCTATGTGGTCTGTCTGCATGGTGCCTAGAACTTTTT
CCATCTGACCTAGGATGCTTCTGAAGCAGTCCCCCTGGGCAGCTGTCTGGTATTTAGGATATACCTGTGAGAAAAGTTTC
TTACAAACCTAATCTACTATGTTTATTCCTGAACTCAAAAAGTTCATTGACTGTTCAAATCCTGAAATTTTCTCTATTTC
CATAAGGCTGAATTAAAAGTACTTTGTTAAAGGTAGTAGCCATGGCAAAAGAAAAACCACTGTTCTGTAGAAAAACTCAT
TCAATATTTACAATCTTTTCTAATCAGAGATTAGATCCTGAAGAGAAAGGTTCATATATATATATATATATATATATATA
TATATATTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTACTCCACTGTCATTGTGACTAAGGATTCATGAACTAAGACCCC
TCCCTCAGCTCTTGGTGGCACATGGTGACAGCATGCTCAGAGCAAAGGTGCTCCCCATGCCTCTTCTGGGGCTGCACTGA
CTGCAGGTACCTCCCCTCTCTACATCCCACACCACTGATACCAAAAACCCCCTCCTTTCTCCTGTACTGATGACTCTGTA
GCTTTAACCAGGGCGGCGGTGTCACTCTAAATGTCACCTTGGCATTCAGCCCCATAGAGTGGGGAAAATTCCCTCACCTG
TTTCTCTTTGACTGTTCAGTCCTCTTCAATTAAAATCTTAATTTTACAAGCGAGGAAATGAGAGTGTTTCTTGTAGGGGT
GTAGTGAGAATTTAATAAAACAGTTTAAGGAAAGAAAACAAAAGGTAGTATTGCTGCACTTTCTAGATGGTAAAAAGCAA
ACCACCATGTCTGTTTAATATATATCACCTGCTGGTCCCTCGGTCTAGCAGGCTGAACTGTGTGCCTGGGAATTTTCTTC
TCGCTGTGTGCACCCCTTTACGTCACAGGGTGGACTCTCTTCAGAGTCCTAGTGGAGCAGCTGGCCAGGCTGACATGATC
TGACAACATTGTAGGTTACCACTACCATCTCTCACCGTCTCACTTTCTTCCTAGGGGTCTCCTGCTGCCAGCTAAGTGTG
GGAGAACTTGTGCACGTATCTCCCCTCCGAATCCCAACGATGGGTAACGCCAGCTTTGGCTCCAAGGAACAGAAGCTGCT
GAAGCGGTTGCGGCTTCTGCCCGCCCTGCTTATCCTCCGCGCCTTCAAGCCCCACAGGAAGATCAGAGATTACCGCGTCG
TGGTAGTCGGCACCGCTGGTGTGGGGAAAAGTACGCTGCTGCACAAGTGGGCGAGCGGCAACTTCCGTCATGAGTACCTG
CCGACCATTGAAAATACCTACTGCCAGTTGCTGGGCTGCAGCCACGGTGTGCTTTCCCTGCACATCACCGACAGCAAGAG
TGGCGACGGCAACCGCGCTCTGCAGCGCCACGTTATAGCCCGGGGCCACGCCTTCGTCCTGGTCTACTCAGTCACCAAGA
AGGAAACCCTGGAAGAGCTGAAGGCCTTCTATGAGCTGATCTGCAAGATCAAAGGTAACAACCTGCATAAGTTCCCCATC
GTGCTGGTGGGCAATAAAAGTGATGACACCCACCGGGAGGTGGCCCTGAATGATGGTGCCACCTGTGCGATGGAGTGGAA
TTGCGCCTTCATGGAGATTTCAGCCAAGACCGATGTGAATGTGCAGGAGCTGTTCCACATGCTGCTGAATTACAAGAAAA
AGCCCACCACCGGCCTCCAGGAGCCCGAGAAGAAATCCCAGATGCCCAACACCACTGAGAAGCTGCTTGACAAGTGCATA
ATCATGTGAGCCCTGGGCCTTAAGAGCCAGCTCTTCCTATCCTGTAGCGTGTAGAAAACGTGGACTCATTTCACTATGTT
ACATGTACATGGTTGATTTTGTGCTGTTGTTTGGACTGTAACATCCATGTTGTCAATACGTATACCTTGTAAGTGGATAA
CTTTTCTTTTTCCCAGGCCAGAGAATTCAAATTGTTAAAACATTGGCATTTGAAGAGGAGAACAAAATGTAGCATGATGT
ATTTAAAGTAAGGCCTTTAGTAATGAATGTAATGAGAGAAAATGTTTTGAAAAGAACAAAACATCAAAATGAATAGAAAG
AAAAATTGGAAGGCGTCCTTTTGGTAACCCGATTATTGTGTATTACCTTTAAATATTTCACATCCTGTAAGTGCTTAATC
ATATCTTTTAATTGTGTATTTAAGAAAAGTGTTTTCACAACAAAAGCTTTTGATAAATTGCTGCGTGACATATACTAAAT
AAAAAAATGAATATGTTGATCATTAGGGGTGTGGGAGCAGAGAAAATTGTGAAAGTGACTCTCACTAAAGATGTTAGTAG
TTTCTCATGTCATTTAAAAATGTTTGAGTATTCTGCATAGCAGTTTGTAAAAGTGTAACAGCTTATTGACTTAATAAAGC
TTTTCCTGCATGCAAT