CDK4

cyclin dependent kinase 4

General Information

Name	cyclin dependent kinase 4
Alias	cyclin-dependent kinase 4 cell division protein kinase 4
Gene_family	Cyclin dependent kinases\|MicroRNA protein coding host genes
organism	Homo sapiens
entrez_id	1019
location	12q14.1
transcript_count	1
exon_count	8

Cross References

Location

by NCBI GRCh38.p14

Summary

Entrez The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported. [provided by RefSeq, Jul 2008]

Stringdb Cyclin-dependent kinase 4; Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complexes and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. [...]

nextProt Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complexes and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also phosphorylates SMAD3 in a cell-cycle-dependent manner and represses its transcriptional activity. Component of the ternary complex, cyclin D/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.

Interactions

NCBI

A	A.Source	B	B.DB	B.Source	Description
CDK4	BioGRID	CLEC16A	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	CDK6	GeneID	BioGRID	Affinity Capture-MS; Co-fractionation; FRET; Negative Genetic
CDK4	BioGRID	CDK3	GeneID	BioGRID	Negative Genetic
CDK4	BioGRID	CDK2	GeneID	BioGRID	Co-fractionation; Negative Genetic
CDK4	BioGRID	CAPRIN1	GeneID	BioGRID	Affinity Capture-Western
CDK4	BioGRID	IKBIP	GeneID	BioGRID	Affinity Capture-Western
CDK4	BioGRID	HSP90AB1	GeneID	BioGRID	Affinity Capture-MS; Reconstituted Complex
CDK4	BioGRID	TRIM67	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	CCNF	GeneID	BioGRID	Affinity Capture-MS; Proximity Label-MS
CDK4	BioGRID	TIPARP	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	CDC37	GeneID	BioGRID	Affinity Capture-Luminescence; Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; PCA; Reconstituted Complex; Two-hybrid
CDK4	BioGRID	CDKN1B	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Co-localization; Reconstituted Complex
CDK4	BioGRID	CCND3	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Reconstituted Complex; Two-hybrid
CDK4	BioGRID	CDKN2D	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex; Two-hybrid
CDK4	BioGRID	CDKN2C	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; FRET; Reconstituted Complex; Two-hybrid
CDK4	BioGRID	CDKN2B	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; FRET; Reconstituted Complex; Two-hybrid
CDK4	BioGRID	CDKN2A	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; FRET; Protein-peptide; Reconstituted Complex; Two-hybrid
CDK4	BioGRID	HSP90AA1	GeneID	BioGRID	Affinity Capture-Luminescence; Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Reconstituted Complex
CDK4	BioGRID	GUSB	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	FKBP5	GeneID	BioGRID	Affinity Capture-Luminescence; Affinity Capture-MS
CDK4	BioGRID	PRKN	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	CDKN1A	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Co-fractionation; Reconstituted Complex
CDK4	BioGRID	CCND1	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Co-localization; Reconstituted Complex; Two-hybrid
CDK4	BioGRID	CUL3	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	PCNA	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Co-fractionation
CDK4	BioGRID	CDK1	GeneID	BioGRID	Co-fractionation
CDK4	BioGRID	CCNA2	GeneID	BioGRID	Affinity Capture-Western; Co-fractionation
CDK4	BioGRID	PTK2	GeneID	BioGRID	Affinity Capture-Western
CDK4	BioGRID	CDH1	GeneID	BioGRID	Affinity Capture-Western
CDK4	BioGRID	FARP2	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
CDK4	BioGRID	MYC	GeneID	BioGRID	Affinity Capture-MS; Biochemical Activity; FRET; Negative Genetic; Two-hybrid
CDK4	BioGRID	ANKRD52	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	RIT1	GeneID	BioGRID	Negative Genetic
CDK4	BioGRID	DSG1	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	RBL2	GeneID	BioGRID	Affinity Capture-MS; Biochemical Activity
CDK4	BioGRID	FKBP6	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	HSP90AA5P	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	HSP90AB4P	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	VSIG8	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	PRR14L	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	OGFRL1	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	HSP90AB3P	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	GFER	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	FGR	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	CDKN1C	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
CDK4	BioGRID	CCND2	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; FRET; Two-hybrid
CDK4	BioGRID	RCAN3	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	OGFR	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	DCAF6	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	NPAS1	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	UBQLN2	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	FBXO8	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
CDK4	BioGRID	RIGI	GeneID	BioGRID	Affinity Capture-RNA
CDK4	BioGRID	UFL1	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	TUBB	GeneID	BioGRID	Proximity Label-MS
CDK4	BioGRID	MAPK1	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	AK2	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	SSR1	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	SLC25A1	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	RIN3	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	MRPS34	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	ORF1ab	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	USP51	GeneID	BioGRID	Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
CDK4	BioGRID	RB1	GeneID	BioGRID	Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
CDK4	BioGRID	PRKAA1	GeneID	BioGRID	Affinity Capture-Western
CDK4	BioGRID	AGAP2	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
CDK4	BioGRID	CCAR2	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	E7	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	ZNF655	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
CDK4	BioGRID	APC	GeneID	BioGRID	Negative Genetic
CDK4	BioGRID	TP53	GeneID	BioGRID	Affinity Capture-Western; FRET; Negative Genetic
CDK4	BioGRID	FASN	GeneID	BioGRID	Positive Genetic
CDK4	BioGRID	PLK1	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	INCA1	GeneID	BioGRID	Two-hybrid
CDK4	BioGRID	HOOK1	GeneID	BioGRID	Two-hybrid
CDK4	BioGRID	IKZF3	GeneID	BioGRID	Two-hybrid
CDK4	BioGRID	TRIM28	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	OGDHL	GeneID	BioGRID	Two-hybrid
CDK4	BioGRID	PGRMC1	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	BIRC3	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	N	GeneID	BioGRID	Affinity Capture-Western
CDK4	BioGRID	LMBR1L	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	FBXL6	GeneID	BioGRID	Affinity Capture-Western
CDK4	BioGRID	H1-1	GeneID	BioGRID	Biochemical Activity
CDK4	BioGRID	CLUAP1	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	TEAD2	GeneID	BioGRID	FRET
CDK4	BioGRID	CUL4A	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	TSC1	GeneID	BioGRID	FRET
CDK4	BioGRID	TERT	GeneID	BioGRID	FRET
CDK4	BioGRID	STK11	GeneID	BioGRID	FRET
CDK4	BioGRID	RAF1	GeneID	BioGRID	FRET
CDK4	BioGRID	MAP2K5	GeneID	BioGRID	FRET
CDK4	BioGRID	MAP2K3	GeneID	BioGRID	FRET
CDK4	BioGRID	PDGFRA	GeneID	BioGRID	FRET
CDK4	BioGRID	NF2	GeneID	BioGRID	FRET
CDK4	BioGRID	MET	GeneID	BioGRID	FRET
CDK4	BioGRID	MAP3K5	GeneID	BioGRID	FRET
CDK4	BioGRID	MDM4	GeneID	BioGRID	FRET
CDK4	BioGRID	IGF1R	GeneID	BioGRID	FRET
CDK4	BioGRID	HIF1A	GeneID	BioGRID	FRET
CDK4	BioGRID	HGF	GeneID	BioGRID	FRET
CDK4	BioGRID	GRM1	GeneID	BioGRID	FRET
CDK4	BioGRID	FGFR4	GeneID	BioGRID	FRET
CDK4	BioGRID	ERBB2	GeneID	BioGRID	FRET; Negative Genetic
CDK4	BioGRID	EPHA2	GeneID	BioGRID	FRET
CDK4	BioGRID	MAPK14	GeneID	BioGRID	FRET
CDK4	BioGRID	ARNT	GeneID	BioGRID	FRET
CDK4	BioGRID	ARAF	GeneID	BioGRID	FRET
CDK4	BioGRID	AKT1	GeneID	BioGRID	FRET
CDK4	BioGRID	CDK4	GeneID	BioGRID	FRET
CDK4	BioGRID	CD44	GeneID	BioGRID	FRET
CDK4	BioGRID	CCNE1	GeneID	BioGRID	Affinity Capture-Western; FRET
CDK4	BioGRID	LATS2	GeneID	BioGRID	FRET
CDK4	BioGRID	RASSF1	GeneID	BioGRID	FRET
CDK4	BioGRID	KDELR2	GeneID	BioGRID	FRET
CDK4	BioGRID	BECN1	GeneID	BioGRID	FRET
CDK4	BioGRID	GLIS2	GeneID	BioGRID	FRET
CDK4	BioGRID	FZR1	GeneID	BioGRID	FRET
CDK4	BioGRID	BMH1	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	BMH2	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	IKBKG	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	HRAS	GeneID	BioGRID	Proximity Label-MS
CDK4	BioGRID	PHB1	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	STUB1	GeneID	BioGRID	Biochemical Activity
CDK4	BioGRID	CDC48	GeneID	BioGRID	Biochemical Activity
CDK4	BioGRID	CNTN2	GeneID	BioGRID	Reconstituted Complex
CDK4	BioGRID	RPA2	GeneID	BioGRID	Affinity Capture-Western
CDK4	BioGRID	RPA1	GeneID	BioGRID	Affinity Capture-Western
CDK4	BioGRID	SOX2	GeneID	BioGRID	Proximity Label-MS
CDK4	BioGRID	RECQL4	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	LARP7	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	HEXIM1	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	SPOP	GeneID	BioGRID	Affinity Capture-Western; Biochemical Activity
CDK4	BioGRID	LNX2	GeneID	BioGRID	Two-hybrid
CDK4	BioGRID	UBE3A	GeneID	BioGRID	Biochemical Activity
CDK4	BioGRID	PAQR4	GeneID	BioGRID	Affinity Capture-Western
CDK4	BioGRID	EGLN2	GeneID	BioGRID	Affinity Capture-Western
CDK4	BioGRID	CNOT7	GeneID	BioGRID	Affinity Capture-Western; Two-hybrid
CDK4	BioGRID	FBXO4	GeneID	BioGRID	Affinity Capture-Western
CDK4	BioGRID	PIAS1	GeneID	BioGRID	Two-hybrid
CDK4	BioGRID	SKP2	GeneID	BioGRID	Affinity Capture-Western
CDK4	BioGRID	EIF4EBP2	GeneID	BioGRID	Two-hybrid
CDK4	BioGRID	EGLN3	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	GATA2	GeneID	BioGRID	Affinity Capture-Western
CDK4	BioGRID	ATXN3	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	PSMD10	GeneID	BioGRID	Protein-peptide; Reconstituted Complex; Two-hybrid
CDK4	BioGRID	CEBPA	GeneID	BioGRID	Affinity Capture-Western; Co-fractionation; Reconstituted Complex
CDK4	BioGRID	E2F4	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	DNAJC9	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	PTPN1	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	PTPN21	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	VTN	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	FNIP1	GeneID	BioGRID	Affinity Capture-Western
CDK4	BioGRID	MTMR14	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	FNIP2	GeneID	BioGRID	Affinity Capture-Western
CDK4	BioGRID	JAK3	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	MTMR8	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	USP17L2	GeneID	BioGRID	Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
CDK4	BioGRID	YBX3	GeneID	BioGRID	Reconstituted Complex; Two-hybrid
CDK4	BioGRID	CHEK2	GeneID	BioGRID	Negative Genetic
CDK4	BioGRID	PTEN	GeneID	BioGRID	Positive Genetic
CDK4	BioGRID	PRKDC	GeneID	BioGRID	Negative Genetic
CDK4	BioGRID	HDAC1	GeneID	BioGRID	Negative Genetic
CDK4	BioGRID	VHL	GeneID	BioGRID	Negative Genetic
CDK4	BioGRID	TOP1	GeneID	BioGRID	Negative Genetic
CDK4	BioGRID	BCL2	GeneID	BioGRID	Negative Genetic
CDK4	BioGRID	UBXN10	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	GLI1	GeneID	BioGRID	Affinity Capture-MS; Biochemical Activity
CDK4	BioGRID	SMAD3	GeneID	BioGRID	Biochemical Activity; Co-localization
CDK4	BioGRID	SORBS1	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	CEP135	GeneID	BioGRID	Proximity Label-MS
CDK4	BioGRID	IQGAP1	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	CDK13	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	SMTN	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	ASPM	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	TMEM126A	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	ZC3H14	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	ZNFX1	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	NUP133	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	ANKRA2	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	NTRK1	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	EIF1AX	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	LIMK2	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	RELA	GeneID	BioGRID	Affinity Capture-Western
CDK4	BioGRID	TARDBP	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	CAMK1	GeneID	BioGRID	Biochemical Activity
CDK4	BioGRID	PTMA	GeneID	BioGRID	Co-purification
CDK4	BioGRID	HSPA8	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western
CDK4	BioGRID	KLHL32	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	TRAP1	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	UCHL1	GeneID	BioGRID	Affinity Capture-Western
CDK4	BioGRID	Rb1	GeneID	BioGRID	Biochemical Activity
CDK4	BioGRID	SKP1	GeneID	BioGRID	Two-hybrid
CDK4	BioGRID	SHOX2	GeneID	BioGRID	Biochemical Activity
CDK4	BioGRID	RBL1	GeneID	BioGRID	Biochemical Activity
CDK4	BioGRID	PGD	GeneID	BioGRID	Two-hybrid
CDK4	BioGRID	OTX2	GeneID	BioGRID	Biochemical Activity
CDK4	BioGRID	MCM2	GeneID	BioGRID	Reconstituted Complex
CDK4	BioGRID	IL15RA	GeneID	BioGRID	Two-hybrid
CDK4	BioGRID	FOXM1	GeneID	BioGRID	Biochemical Activity
CDK4	BioGRID	DUSP9	GeneID	BioGRID	Two-hybrid
CDK4	BioGRID	CDC6	GeneID	BioGRID	Biochemical Activity
CDK4	BioGRID	ZNF101	GeneID	BioGRID	Biochemical Activity
CDK4	BioGRID	ZNF335	GeneID	BioGRID	Biochemical Activity
CDK4	BioGRID	WDR33	GeneID	BioGRID	Biochemical Activity
CDK4	BioGRID	BCL11A	GeneID	BioGRID	Biochemical Activity
CDK4	BioGRID	ZNF219	GeneID	BioGRID	Biochemical Activity
CDK4	BioGRID	SENP3	GeneID	BioGRID	Biochemical Activity
CDK4	BioGRID	ANKRD12	GeneID	BioGRID	Biochemical Activity
CDK4	BioGRID	MAPRE2	GeneID	BioGRID	Two-hybrid
CDK4	BioGRID	CIB1	GeneID	BioGRID	Two-hybrid
CDK4	BioGRID	CDC7	GeneID	BioGRID	Reconstituted Complex
CDK4	BioGRID	SLBP	GeneID	BioGRID	Biochemical Activity
CDK4	BioGRID	MZF1	GeneID	BioGRID	Biochemical Activity
CDK4	BioGRID	VCP	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	SMAD2	GeneID	BioGRID	Biochemical Activity
CDK4	BioGRID	UBTF	GeneID	BioGRID	Biochemical Activity
CDK4	BioGRID	POLD1	GeneID	BioGRID	Biochemical Activity
CDK4	BioGRID	PPP1CA	GeneID	BioGRID	Affinity Capture-Western; Co-fractionation
CDK4	BioGRID	APP	GeneID	BioGRID	Reconstituted Complex
CDK4	BioGRID	BRCA1	GeneID	BioGRID	Biochemical Activity; Reconstituted Complex
CDK4	BioGRID	H1-0	GeneID	BioGRID	Biochemical Activity
CDK4	BioGRID	COPS5	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	COPS6	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	CUL1	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	CUL4B	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	RPL34	GeneID	BioGRID	Reconstituted Complex
CDK4	BioGRID	PSMA6	GeneID	BioGRID	Affinity Capture-Western
CDK4	BioGRID	MARCKS	GeneID	BioGRID	Biochemical Activity
CDK4	BioGRID	ARRB2	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	CDK5R1	GeneID	BioGRID	Affinity Capture-Western
CDK4	BioGRID	PSMD9	GeneID	BioGRID	Affinity Capture-Western
CDK4	BioGRID	H1-3	GeneID	BioGRID	Biochemical Activity
CDK4	BioGRID	LUC7L2	GeneID	BioGRID	Two-hybrid
CDK4	BioGRID	TRMT2A	GeneID	BioGRID	Two-hybrid
CDK4	BioGRID	DDAH2	GeneID	BioGRID	Two-hybrid
CDK4	BioGRID	HMGXB3	GeneID	BioGRID	Two-hybrid
CDK4	BioGRID	SETDB1	GeneID	BioGRID	Two-hybrid
CDK4	BioGRID	DAZAP2	GeneID	BioGRID	Two-hybrid
CDK4	BioGRID	ZBTB16	GeneID	BioGRID	Two-hybrid
CDK4	BioGRID	TK1	GeneID	BioGRID	Two-hybrid
CDK4	BioGRID	SNCA	GeneID	BioGRID	Two-hybrid
CDK4	BioGRID	QARS1	GeneID	BioGRID	Two-hybrid
CDK4	BioGRID	PKM	GeneID	BioGRID	Two-hybrid
CDK4	BioGRID	IRF8	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	ATP5F1B	GeneID	BioGRID	Two-hybrid
CDK4	BioGRID	ANXA7	GeneID	BioGRID	Two-hybrid
CDK4	BioGRID	APLP1	GeneID	BioGRID	Two-hybrid
CDK4	BioGRID	UHRF2	GeneID	BioGRID	Far Western
CDK4	BioGRID	PPP2R1B	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western
CDK4	BioGRID	PPP2R1A	GeneID	BioGRID	Affinity Capture-Western
CDK4	BioGRID	ARID4A	GeneID	BioGRID	Biochemical Activity
CDK4	BioGRID	WDR77	GeneID	BioGRID	Affinity Capture-Western
CDK4	BioGRID	PRMT5	GeneID	BioGRID	Affinity Capture-Western
CDK4	BioGRID	HSP82	GeneID	BioGRID	Affinity Capture-Western
CDK4	BioGRID	TSPYL2	GeneID	BioGRID	Biochemical Activity
CDK4	BioGRID	NCOA2	GeneID	BioGRID	Reconstituted Complex
CDK4	BioGRID	SAP25	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	CDT1	GeneID	BioGRID	Affinity Capture-Western
CDK4	BioGRID	SP1	GeneID	BioGRID	Affinity Capture-Western
CDK4	Protein	NOL12	GeneID	HPRD
CDK4	Protein	SERTAD1	GeneID	HPRD
CDK4	Protein	ZNF655	GeneID	HPRD
CDK4	Protein	CDC7	GeneID	HPRD
CDK4	Protein	VTA1	GeneID	HPRD
CDK4	Protein	CDC45	GeneID	HPRD
CDK4	Protein	NCOA2	GeneID	HPRD
CDK4	Protein	SETDB1	GeneID	HPRD
CDK4	Protein	CDC37	GeneID	HPRD
CDK4	Protein	ORC3	GeneID	HPRD
CDK4	Protein	CNOT7	GeneID	HPRD
CDK4	Protein	PSMD10	GeneID	HPRD
CDK4	Protein	CDKN2C	GeneID	HPRD
CDK4	Protein	BIRC5	GeneID	HPRD
CDK4	Protein	BMPR1B	GeneID	HPRD
CDK4	Protein	PPP2R1B	GeneID	HPRD
CDK4	Protein	SMAD3	GeneID	HPRD
CDK4	Protein	SMAD2	GeneID	HPRD
CDK4	Protein	CDKN2D	GeneID	HPRD
CDK4	Protein	CDKN1C	GeneID	HPRD
CDK4	Protein	CDKN1B	GeneID	HPRD
CDK4	Protein	CDKN2B	GeneID	HPRD
CDK4	Protein	CDKN2A	GeneID	HPRD
CDK4	Protein	IFI27	GeneID	HPRD
CDK4	Protein	TGFBR1	GeneID	HPRD
CDK4	Protein	PRKAR1A	GeneID	HPRD
CDK4	Protein	PTMA	GeneID	HPRD
CDK4	Protein	RB1	GeneID	HPRD
CDK4	Protein	CCND1	GeneID	HPRD
CDK4	Protein	MYOD1	GeneID	HPRD
CDK4	Protein	BAG6	GeneID	HPRD
CDK4	Protein	CCND3	GeneID	HPRD
CDK4	Protein	CCND2	GeneID	HPRD
CDK4	Protein	RBL1	GeneID	HPRD
CDK4	Protein	MCM2	GeneID	HPRD
CDK4	Protein	CDKN1A	GeneID	HPRD
CDK4	Protein	CEBPA	GeneID	HPRD
CDK4	Protein	CAPNS1	GeneID	HPRD
CDK4	Protein	BRCA1	GeneID	HPRD
CDK4	Protein	RFC1	GeneID	HPRD
CDK4	Protein	RFC4	GeneID	HPRD
CDK4	BioGRID	IME2	GeneID	BioGRID	Phenotypic Suppression
CDK4	BioGRID	MYOD1	GeneID	BioGRID	Reconstituted Complex; Two-hybrid
CDK4	BioGRID	BIRC5	GeneID	BioGRID	Affinity Capture-Western
CDK4	BioGRID	RFC1	GeneID	BioGRID	Affinity Capture-Western
CDK4	BioGRID	SERTAD1	GeneID	BioGRID	Reconstituted Complex
CDK4	BioGRID	BAG6	GeneID	BioGRID	Two-hybrid
CDK4	BioGRID	CAPNS1	GeneID	BioGRID	Two-hybrid
CDK4	BioGRID	ACTR3B	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	RPRM	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	UBXN1	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	GEMIN4	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	DBNL	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	SMC3	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	SMC1A	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	LYN	GeneID	BioGRID	Affinity Capture-MS
CDK4	BioGRID	VTA1	GeneID	BioGRID	Two-hybrid
CDK4	Protein	CDKN2C	GeneID	BIND	An unspecified isoform of p18 interacts with cdk4. This interaction was modeled on a demonstrated interaction between human p18 and cdk4 from an unspecified species.
CDK4	Protein	CDKN2A	GeneID	BIND	p16 interacts with cdk4. This interaction was modeled on a demonstrated interaction between human p16 and cdk4 from an unspecified species.
CDK4	Protein	CDKN1A	GeneID	BIND	Cdk4 interacts with p21.
CDK4	Protein	CDKN2A	GeneID	BIND	p16 interacts with cdk4.
CDK4	Protein	CDKN2A	GeneID	BIND	p16 interacts with CDK4. This interaction was modeled on a demonstrated interaction between human p16 and CDK4 from an unspecified species.
CDK4	Nucleotide	MYC	GeneID	BIND	MYC (c-Myc) interacts with CDK4 promoter.
CDK4	Protein	tax	GeneID	BIND	Tax interacts with CDK4.
CDK4	Protein	BRCA1	GeneID	BIND	BRCA1 associates with CDK4
CDK4	Protein	CCND1	GeneID	BIND	CCND1 (cyclin D1) interacts with CDK4.
CDK4	Protein	CDKN2A	GeneID	BIND	CDKN2A interacts with CDK4
CDK4	Protein	CCND1	GeneID	BIND	CDK4 interacts with Cyclin D1. This interaction was modelled on a demonstrated interaction between human CDK4 and Cyclin D1 from an unspecified species.
CDK4	Protein	CCND2	GeneID	BIND	CCND2 interacts with CDK4
CDK4	Protein	RB1	GeneID	BIND	CDK4 phosphorylates Rb carboxy-terminus. This interaction was modelled on a demonstrated interaction between human Rb and mouse CDK4.
CDK4	Protein	SMAD2	GeneID	BIND	CDK4 phosphorylates Smad2. This interaction was modelled on a demonstrated interaction between Smad2 from an unspecified species and mouse CDK4.
CDK4	Protein	SMAD3	GeneID	BIND	CDK4 phosphorylates Smad3 on Thr8, Thr179, Ser204, Ser208 and Ser213. This interaction was modelled on a demonstrated interaction between Smad3 from an unspecified species and mouse CDK4.

StringDB

A	B	experiments	database	textmining	combined score	hadb	nhadb
CDK4	HIST2H2AA3	0	0	184	251	1	1
CDK4	HDAC4	0	0	248	297	1	2
CDK4	E2F7	0	0	689	759	1	1
CDK4	PRRX1	0	0	66	182	1	1
CDK4	LSM2	0	0	0	174	1	1
CDK4	KIF27	0	0	0	201	1	1
CDK4	CTBP1	0	0	189	212	1	1
CDK4	HSP90AA1	870	0	989	999	1	2
CDK4	DDX4	0	0	0	207	1	1
CDK4	RFC4	213	0	157	455	1	1
CDK4	ATF2	0	0	134	152	1	1
CDK4	TP73	0	0	243	373	1	2
CDK4	RANGAP1	0	0	63	152	1	1
CDK4	SOX2	114	0	457	559	1	2
CDK4	SET	0	0	54	286	1	1
CDK4	HIST2H2AA	0	0	184	251	1	1
CDK4	GRAP2	0	0	297	297	1	1
CDK4	TES	0	0	95	256	1	1
CDK4	ARHGDIA	0	0	127	178	1	1
CDK4	FGF1	0	0	189	271	1	1
CDK4	HOXA5	0	0	140	165	1	1
CDK4	YEATS4	0	0	296	341	1	1
CDK4	RAD21L1	0	0	0	159	1	1
CDK4	GNA14	0	0	0	159	1	1
CDK4	NOBOX	0	0	0	160	1	1
CDK4	WHSC1L1	0	0	134	175	1	1
CDK4	NCAPG2	0	0	81	176	1	1
CDK4	USP17L2	270	0	169	374	1	1
CDK4	ENSG00000137843	0	0	81	196	1	1
CDK4	CRYZ	0	0	113	156	1	1
CDK4	JUNB	0	0	186	382	1	1
CDK4	NIPBL	0	0	87	158	1	1
CDK4	ANXA4	0	0	57	159	1	1
CDK4	KIFC2	0	0	0	244	1	1
CDK4	BNIP3	0	0	194	194	1	2
CDK4	SLC16A1	0	0	100	152	1	1
CDK4	SQSTM1	0	0	194	200	1	2
CDK4	TFDP1	0	900	320	944	1	1
CDK4	MMP9	0	0	518	537	1	2
CDK4	STK38	0	0	90	351	1	1
CDK4	RND1	0	0	70	168	1	1
CDK4	MAPK3	0	0	603	327	1	2
CDK4	LRRC9	0	0	0	185	1	1
CDK4	TSPYL2	270	0	435	605	1	1
CDK4	THY1	0	0	155	173	1	1
CDK4	CUL4A	44	0	232	355	1	1
CDK4	BID	0	0	131	150	1	2
CDK4	GNRH1	0	0	146	166	1	1
CDK4	CDCA7	0	0	93	204	1	1
CDK4	RAD51AP1	0	0	180	285	1	1
CDK4	GSN	0	0	103	189	1	1
CDK4	HIST1H3D	0	0	194	311	1	1
CDK4	AR	0	0	523	530	1	2
CDK4	CDKN1A	982	900	989	999	1	2
CDK4	SPP1	0	0	244	243	1	2
CDK4	ECT2	0	0	134	307	1	1
CDK4	BAX	0	0	374	383	1	2
CDK4	TIMP1	0	0	262	278	1	1
CDK4	LRRC46	0	0	0	185	1	1
CDK4	F10	0	0	322	321	1	1
CDK4	GNA12	0	0	0	213	1	1
CDK4	RCAN2	0	0	306	322	1	1
CDK4	ENSG00000251537	0	0	0	184	1	1
CDK4	CCNY	0	900	179	934	1	1
CDK4	DUSP16	0	0	45	196	1	1
CDK4	AURKA	0	0	508	508	1	2
CDK4	IFT122	0	0	0	248	1	1
CDK4	RASL12	0	0	0	154	1	1
CDK4	PTPRC	0	0	280	348	1	1
CDK4	BCL2L12	0	0	128	195	1	1
CDK4	BCR	0	0	147	209	1	2
CDK4	UMPS	0	0	66	185	1	1
CDK4	LMX1A	0	0	57	174	1	1
CDK4	DMC1	0	800	0	822	1	1
CDK4	ITGAV	0	0	136	154	1	1
CDK4	TOMM34	0	0	0	162	1	1
CDK4	BCL10	0	0	117	181	1	1
CDK4	KPNA5	0	0	0	210	1	1
CDK4	IGFBP2	0	0	210	210	1	1
CDK4	H2AFB1	0	900	0	909	1	1
CDK4	PTPRO	0	0	0	177	1	1
CDK4	CCNB2	0	900	467	977	1	1
CDK4	RALB	0	0	90	197	1	2
CDK4	ICAM1	0	0	223	223	1	2
CDK4	RNF8	0	0	66	170	1	1
CDK4	SOX9	0	0	286	296	1	1
CDK4	FOXA3	0	0	70	203	1	1
CDK4	NEUROG1	0	0	145	167	1	1
CDK4	MAX	0	0	172	205	1	2
CDK4	FYN	0	0	212	243	1	1
CDK4	GRB2	0	0	293	308	1	1
CDK4	H3F3C	0	0	0	180	1	1
CDK4	NFKBIE	0	0	108	203	1	1
CDK4	CREB3L2	0	0	280	280	1	1
CDK4	ARHGAP11A	0	0	0	152	1	1
CDK4	CDC14B	0	0	0	314	1	1
CDK4	JAG1	0	0	395	415	1	1
CDK4	ASIP	0	0	112	487	1	1
CDK4	CEP55	0	0	74	151	1	1
CDK4	SOD1	0	0	125	243	1	2
CDK4	KPNA2	0	0	113	334	1	1
CDK4	TBL1X	0	0	181	358	1	1
CDK4	CDC25C	0	0	563	776	1	2
CDK4	ARNT	178	0	456	545	1	2
CDK4	KIF3C	0	0	0	201	1	1
CDK4	SMC1A	65	0	150	378	1	1
CDK4	MNT	0	0	209	240	1	1
CDK4	CETN2	0	0	140	224	1	1
CDK4	SMC3	85	0	107	414	1	1
CDK4	BMI1	0	0	581	608	1	1
CDK4	NOP2	0	0	96	202	1	1
CDK4	ANKRD44	0	0	0	208	1	1
CDK4	ATAD3A	0	0	0	167	1	1
CDK4	CENPE	0	0	125	307	1	1
CDK4	LIN37	0	0	181	203	1	1
CDK4	ZBTB7A	0	0	100	158	1	1
CDK4	MOB2	0	0	0	214	1	1
CDK4	RAP2C	0	0	0	154	1	1
CDK4	HIST1H2BK	0	600	0	621	1	1
CDK4	COX18	0	0	0	158	1	1
CDK4	UCHL1	270	0	103	345	1	2
CDK4	SEPT4	0	0	122	196	1	1
CDK4	CLIP4	0	0	0	285	1	1
CDK4	IRS2	0	0	253	252	1	1
CDK4	NFATC3	0	0	192	192	1	1
CDK4	KRT8	0	0	208	226	1	1
CDK4	NEDD9	0	0	123	150	1	1
CDK4	CSNK1G2	0	0	0	173	1	1
CDK4	ENSG00000270024	0	0	150	292	1	1
CDK4	PRKACB	0	0	67	267	1	1
CDK4	NCOA3	0	0	273	279	1	1
CDK4	RUNX3	0	0	243	255	1	1
CDK4	SERTAD2	0	0	216	216	1	1
CDK4	NUP107	0	0	73	165	1	1
CDK4	DNTT	0	0	391	391	1	1
CDK4	EIF2AK1	0	0	0	152	1	1
CDK4	CCNA2	486	900	941	997	1	1
CDK4	TK1	0	0	263	407	1	1
CDK4	NCOA2	270	0	134	346	1	1
CDK4	HIC1	0	0	139	194	1	1
CDK4	AIF1	0	0	62	152	1	2
CDK4	SIK2	0	0	297	182	1	1
CDK4	ERBB4	0	0	394	197	1	1
CDK4	GSTA4	0	0	0	197	1	1
CDK4	KIF1B	0	0	57	215	1	1
CDK4	JAK3	375	0	304	512	1	1
CDK4	ZBTB16	63	0	96	174	1	1
CDK4	PIK3CG	0	0	310	376	1	1
CDK4	PTPN21	83	0	0	177	1	1
CDK4	DIS3L2	0	0	70	161	1	1
CDK4	CDH17	0	0	265	294	1	1
CDK4	TJP3	0	0	123	189	1	1
CDK4	RABEPK	0	0	0	152	1	1
CDK4	LRRC48	0	0	0	185	1	1
CDK4	SI	0	0	273	273	1	1
CDK4	CYP19A1	0	0	557	557	1	2
CDK4	ENSG00000173366	0	0	90	179	1	1
CDK4	GPSM2	0	0	60	155	1	1
CDK4	ASF1B	0	0	0	295	1	1
CDK4	JUN	0	0	599	708	1	2
CDK4	ASF1A	0	0	72	264	1	1
CDK4	SKA3	0	0	48	185	1	1
CDK4	CTDSP2	0	0	187	258	1	1
CDK4	CDCA3	0	0	113	248	1	1
CDK4	FBL	0	0	127	355	1	2
CDK4	TAF1	0	0	125	182	1	1
CDK4	DAPK1	0	0	259	174	1	2
CDK4	PITPNC1	0	0	48	215	1	1
CDK4	CCNJL	0	540	0	691	1	1
CDK4	CYP1B1	0	0	170	169	1	1
CDK4	LHX5	0	0	0	160	1	1
CDK4	GATA4	0	0	244	245	1	2
CDK4	ETV5	0	0	160	159	1	1
CDK4	SEPT9	0	0	101	169	1	1
CDK4	SMARCA2	0	650	194	744	1	1
CDK4	MC1R	0	0	566	566	1	1
CDK4	PDZD2	0	0	0	172	1	1
CDK4	POLR1E	0	0	114	193	1	1
CDK4	ZDHHC13	0	0	89	202	1	1
CDK4	HSPA4	0	0	678	711	1	1
CDK4	PLAUR	0	0	203	203	1	1
CDK4	LPIN3	0	0	0	311	1	1
CDK4	NRARP	0	0	0	151	1	1
CDK4	PTPRK	0	0	103	187	1	1
CDK4	PIK3R1	0	0	456	467	1	1
CDK4	DICER1	0	0	345	387	1	1
CDK4	VARS	0	0	0	206	1	1
CDK4	DDX1	0	0	113	279	1	1
CDK4	LHX8	0	0	0	160	1	1
CDK4	C1QL1	0	0	69	165	1	1
CDK4	HSPB3	0	0	298	298	1	1
CDK4	XPO5	0	0	204	282	1	1
CDK4	PDCD4	0	0	335	363	1	2
CDK4	HIST3H2A	0	0	0	153	1	1
CDK4	TUBD1	0	0	44	246	1	1
CDK4	KPNA7	0	0	0	210	1	1
CDK4	HSP90B1	0	0	325	557	1	1
CDK4	PPARA	0	0	266	278	1	2
CDK4	MRPL24	0	0	0	166	1	1
CDK4	PAICS	0	0	74	311	1	1
CDK4	TRAF6	0	0	150	181	1	2
CDK4	CLSPN	0	0	180	274	1	1
CDK4	FLCN	0	0	150	208	1	1
CDK4	RAC3	0	0	60	180	1	2
CDK4	NWD2	0	0	0	248	1	1
CDK4	CYCS	0	0	670	692	1	2
CDK4	DUSP12	0	0	139	275	1	1
CDK4	GADD45B	0	0	234	234	1	1
CDK4	RGL2	0	0	0	200	1	1
CDK4	CSNK1A1L	0	0	0	421	1	1
CDK4	CAMKK1	0	0	62	206	1	1
CDK4	BMP2	0	0	167	168	1	1
CDK4	EGF	0	0	565	573	1	2
CDK4	KIF6	0	0	0	217	1	1
CDK4	HNF1A	0	0	182	181	1	1
CDK4	PTPN3	0	0	56	153	1	1
CDK4	PLAU	0	0	210	210	1	1
CDK4	GNAZ	0	0	0	199	1	1
CDK4	HAS1	0	0	0	170	1	1
CDK4	NACC1	0	0	0	166	1	1
CDK4	CDC6	128	0	518	820	1	1
CDK4	GAK	0	0	75	254	1	1
CDK4	XRCC1	0	0	216	233	1	1
CDK4	HIST1H2AA	0	900	0	911	1	1
CDK4	RPRD1B	0	0	266	319	1	1
CDK4	CENPF	0	0	204	275	1	1
CDK4	PTK2	0	0	392	183	1	2
CDK4	NXT1	0	0	52	150	1	1
CDK4	FRZB	0	0	145	236	1	1
CDK4	ZNF217	0	0	267	314	1	1
CDK4	MAPK8	0	0	413	248	1	2
CDK4	MUT	0	0	306	318	1	1
CDK4	BRAF	0	0	407	222	1	2
CDK4	GLRX3	0	0	57	175	1	1
CDK4	TNS4	0	0	0	182	1	1
CDK4	MAP2K4	0	0	323	257	1	1
CDK4	MAGOHB	0	0	112	232	1	1
CDK4	CDK11A	0	0	301	217	1	1
CDK4	INCENP	0	0	161	318	1	1
CDK4	SSH1	0	0	0	193	1	1
CDK4	CHD5	0	0	60	246	1	1
CDK4	DIABLO	0	0	330	347	1	2
CDK4	ARHGEF3	0	0	0	192	1	1
CDK4	ANKRD30A	0	0	96	192	1	1
CDK4	KDM2A	0	0	83	184	1	1
CDK4	NUP133	198	0	43	218	1	1
CDK4	GDPD5	0	0	0	207	1	1
CDK4	PPP2R5B	0	0	0	176	1	1
CDK4	GDPD3	0	0	0	207	1	1
CDK4	NT5DC2	0	0	0	188	1	1
CDK4	PRNP	0	0	94	161	1	2
CDK4	CENPW	0	0	0	159	1	1
CDK4	PPP2CB	0	0	0	224	1	1
CDK4	CHKA	0	0	815	823	1	1
CDK4	GATA1	0	0	220	221	1	1
CDK4	DAAM1	0	0	62	245	1	1
CDK4	H3F3B	0	0	260	367	1	1
CDK4	CDK2AP1	0	0	188	287	1	1
CDK4	COPS3	0	0	167	167	1	1
CDK4	SMARCE1	0	650	95	681	1	1
CDK4	MAF	0	0	206	206	1	1
CDK4	XRCC4	0	0	151	150	1	1
CDK4	SSX2	0	0	233	232	1	1
CDK4	PSMB2	0	0	0	180	1	1
CDK4	MAGI3	0	0	74	211	1	1
CDK4	CRYGC	0	0	172	171	1	1
CDK4	PPP1CB	0	0	103	356	1	1
CDK4	ALK	0	0	520	267	1	2
CDK4	MRPS7	0	0	51	167	1	1
CDK4	PAX6	0	0	195	262	1	1
CDK4	ERCC4	0	0	91	240	1	1
CDK4	WNT1	0	0	291	400	1	2
CDK4	TRADD	0	0	205	222	1	1
CDK4	CYP3A4	0	0	247	246	1	1
CDK4	DGCR14	0	0	142	180	1	1
CDK4	HIST1H2BO	0	600	0	621	1	1
CDK4	DUT	0	0	73	304	1	1
CDK4	SIRT6	0	0	232	279	1	2
CDK4	SGK494	0	0	0	385	1	1
CDK4	DUSP8	0	0	62	211	1	1
CDK4	HSPA14	0	0	0	176	1	1
CDK4	FKBP4	0	0	181	236	1	1
CDK4	BUB1B	0	0	358	615	1	1
CDK4	PDGFRA	178	0	594	360	1	1
CDK4	CDK16	0	0	224	179	1	1
CDK4	CDH1	0	0	595	611	1	2
CDK4	NEUROG2	0	0	150	168	1	1
CDK4	IGF2BP1	0	0	123	182	1	1
CDK4	IDH1	0	0	503	526	1	1
CDK4	EPM2A	0	0	0	193	1	2
CDK4	DUSP10	0	0	66	214	1	1
CDK4	EML5	0	0	0	248	1	1
CDK4	LEF1	0	0	260	260	1	1
CDK4	TECR	0	0	113	167	1	1
CDK4	NUMB	0	0	161	199	1	1
CDK4	PDGFRB	0	0	460	204	1	2
CDK4	PRMT6	0	0	448	474	1	1
CDK4	EP300	0	0	393	432	1	2
CDK4	CDK5	0	900	727	920	1	2
CDK4	CHD1	0	0	108	211	1	1
CDK4	TNRC6C	0	650	0	659	1	1
CDK4	IL4	0	0	234	243	1	1
CDK4	WNT9B	0	0	96	222	1	1
CDK4	TPTE	0	0	0	193	1	1
CDK4	NPM3	0	0	57	203	1	1
CDK4	RAP1B	0	0	108	213	1	1
CDK4	SMAD3	634	900	546	982	1	2
CDK4	ANXA8	0	0	296	296	1	1
CDK4	BIRC3	0	0	334	362	1	1
CDK4	BRWD1	0	0	0	248	1	1
CDK4	NAA10	0	0	52	155	1	1
CDK4	RNF123	0	0	135	167	1	1
CDK4	NEU2	0	0	54	199	1	1
CDK4	REC8	0	0	0	159	1	1
CDK4	ROCK1	0	0	302	190	1	2
CDK4	SLBP	128	0	64	237	1	1
CDK4	IDO1	0	0	166	165	1	1
CDK4	EIF4A1	0	0	217	407	1	1
CDK4	SNAI2	0	0	450	459	1	1
CDK4	RPL19	0	0	66	189	1	1
CDK4	CDC37	978	0	907	998	1	1
CDK4	PPP2R1B	232	0	45	271	1	1
CDK4	CCL2	0	0	248	248	1	2
CDK4	CTR9	0	0	0	150	1	1
CDK4	ALB	0	0	464	500	1	2
CDK4	CDC23	0	0	169	524	1	1
CDK4	CD68	0	0	181	181	1	2
CDK4	SGK2	0	0	0	274	1	1
CDK4	HOOK1	649	0	0	673	1	1
CDK4	RCAN3	192	0	304	427	1	1
CDK4	DSCC1	0	0	0	153	1	1
CDK4	RAP2A	0	0	0	154	1	1
CDK4	DUSP9	111	0	90	298	1	1
CDK4	CASP7	0	0	460	518	1	1
CDK4	SYMPK	0	800	108	822	1	1
CDK4	MME	0	0	152	151	1	1
CDK4	CUL1	0	650	369	797	1	1
CDK4	CNTRL	0	0	0	185	1	1
CDK4	PITPNM1	0	0	0	210	1	1
CDK4	CSNK1D	0	0	57	455	1	1
CDK4	ELAVL1	0	0	438	451	1	2
CDK4	BBS10	0	0	0	346	1	1
CDK4	DUSP7	0	0	45	185	1	1
CDK4	LRRC6	0	0	0	185	1	1
CDK4	CENPA	0	0	150	319	1	1
CDK4	PTPRT	0	0	73	160	1	1
CDK4	IMPDH2	0	0	53	340	1	1
CDK4	FMN2	0	0	0	228	1	1
CDK4	PPP1R11	0	0	0	158	1	1
CDK4	ITGA5	0	0	140	172	1	1
CDK4	KRT5	0	0	241	240	1	1
CDK4	MYH6	0	0	171	196	1	1
CDK4	SOX4	0	0	241	257	1	1
CDK4	EIF2AK4	0	0	113	175	1	2
CDK4	DLGAP1	0	0	0	192	1	1
CDK4	RFC3	0	0	134	272	1	1
CDK4	PTPN22	0	0	54	188	1	1
CDK4	EFCAB8	0	0	0	184	1	1
CDK4	EML2	0	0	0	248	1	1
CDK4	RASGRP3	0	0	47	187	1	1
CDK4	GABPB2	0	0	0	160	1	1
CDK4	NCOA1	0	0	157	164	1	1
CDK4	HBEGF	0	0	181	224	1	1
CDK4	FANCC	0	0	181	181	1	1
CDK4	ZNF335	128	0	0	200	1	1
CDK4	EML6	0	0	0	248	1	1
CDK4	RAX2	0	0	0	160	1	1
CDK4	TP53RK	0	0	54	150	1	1
CDK4	JAK2	0	900	458	926	1	2
CDK4	HSPA12B	0	0	0	158	1	1
CDK4	KIAA1549	0	0	217	217	1	1
CDK4	HIST1H1B	0	0	47	266	1	1
CDK4	BRD7	0	0	101	159	1	1
CDK4	CDH2	0	0	500	519	1	1
CDK4	APAF1	0	0	458	479	1	2
CDK4	HDAC6	0	0	294	340	1	2
CDK4	GNAT1	0	0	0	210	1	1
CDK4	CCNI	0	540	89	701	1	1
CDK4	ZBTB10	0	0	97	155	1	1
CDK4	CLU	0	0	171	189	1	2
CDK4	HUWE1	0	0	134	177	1	1
CDK4	MELK	0	0	167	213	1	1
CDK4	BRD4	0	0	371	405	1	2
CDK4	CALM3	0	0	91	227	1	1
CDK4	MYBL1	0	0	209	348	1	1
CDK4	RAD9A	0	0	205	257	1	1
CDK4	TSPAN31	0	0	503	514	1	1
CDK4	KIF7	0	0	0	218	1	1
CDK4	KLF10	0	0	64	157	1	1
CDK4	CDH3	0	0	153	186	1	1
CDK4	APRT	0	0	0	172	1	1
CDK4	NR4A1	0	0	155	154	1	2
CDK4	PSMD10	462	0	982	991	1	1
CDK4	IRAK1	0	0	142	152	1	1
CDK4	CMTM6	0	0	142	164	1	1
CDK4	LMX1B	0	0	0	160	1	1
CDK4	NCOR2	0	0	142	212	1	1
CDK4	PDCD2	0	0	95	156	1	1
CDK4	ANKS1A	0	0	0	179	1	1
CDK4	RAF1	138	0	563	349	1	2
CDK4	RBL1	306	900	825	992	1	1
CDK4	CUL2	0	0	156	242	1	1
CDK4	RREB1	0	0	123	195	1	1
CDK4	VRK3	0	0	0	227	1	1
CDK4	MLIP	0	0	0	642	1	1
CDK4	HDAC2	0	0	362	458	1	1
CDK4	KPNA3	0	0	0	210	1	1
CDK4	TACC1	0	0	182	181	1	1
CDK4	PPP2R5D	0	0	67	199	1	1
CDK4	TNS3	0	0	0	208	1	1
CDK4	GUK1	0	0	0	160	1	1
CDK4	WNT4	0	0	148	213	1	1
CDK4	MAP1A	0	0	63	156	1	2
CDK4	NUP37	0	0	0	261	1	1
CDK4	NFKBIZ	0	0	67	166	1	1
CDK4	LAMA4	0	0	145	163	1	1
CDK4	MDM2	0	0	806	816	1	2
CDK4	TP53	491	0	856	936	1	2
CDK4	CTNNA1	0	0	124	182	1	1
CDK4	KIF5C	0	0	0	220	1	1
CDK4	SHOX	0	0	0	160	1	1
CDK4	RASGRP1	0	0	66	267	1	1
CDK4	MARS	0	0	48	215	1	1
CDK4	FGFR3	0	0	459	194	1	1
CDK4	ASB7	0	0	0	208	1	1
CDK4	LHX1	0	0	47	165	1	1
CDK4	NEDD8	0	0	129	194	1	2
CDK4	SLC2A1	0	0	260	276	1	2
CDK4	ATP2C1	0	0	278	297	1	1
CDK4	KANK1	0	0	45	205	1	1
CDK4	DLGAP5	0	0	102	288	1	1
CDK4	CFLAR	0	0	321	326	1	2
CDK4	EGFR	0	0	718	319	1	2
CDK4	PPP1CC	128	0	95	410	1	1
CDK4	NKX6-1	0	0	150	195	1	1
CDK4	CDC5L	0	0	161	294	1	1
CDK4	ALG11	0	0	0	180	1	1
CDK4	KIF20B	0	0	0	277	1	1
CDK4	RFC1	270	0	0	303	1	1
CDK4	LMBR1L	270	0	0	276	1	1
CDK4	SND1	0	0	445	494	1	1
CDK4	FRS2	0	0	294	294	1	1
CDK4	FBXO16	0	0	0	184	1	1
CDK4	GLTSCR1	0	0	306	321	1	1
CDK4	MBD2	0	0	77	229	1	1
CDK4	BRCA1	675	800	602	973	1	2
CDK4	PDGFB	0	0	260	260	1	2
CDK4	STK11	186	0	508	418	1	2
CDK4	SYNJ1	0	0	0	250	1	1
CDK4	ANKS1B	0	0	65	199	1	1
CDK4	SSR1	274	0	0	274	1	1
CDK4	AREG	0	0	213	213	1	1
CDK4	TCF3	0	0	167	214	1	1
CDK4	BOLA2	0	0	0	156	1	1
CDK4	TOP2A	0	0	373	530	1	1
CDK4	B4GALNT1	0	0	107	432	1	1
CDK4	FUT4	0	0	143	173	1	1
CDK4	CDKN2D	870	900	971	999	1	1
CDK4	MAP3K8	0	0	154	237	1	1
CDK4	FLNA	0	0	710	726	1	1
CDK4	MKNK2	0	0	56	187	1	1
CDK4	LRP5	0	0	139	246	1	1
CDK4	CHGA	0	0	141	159	1	1
CDK4	FBXO24	0	0	0	184	1	1
CDK4	PBK	0	0	181	308	1	1
CDK4	CCNT1	0	900	369	948	1	1
CDK4	MDC1	0	0	193	245	1	1
CDK4	LRP1B	0	0	181	202	1	1
CDK4	INHBA	0	0	100	156	1	1
CDK4	LRRC23	0	0	0	185	1	1
CDK4	CASP10	0	0	260	290	1	1
CDK4	DDX50	0	0	0	163	1	1
CDK4	HIST1H2BH	0	600	0	621	1	1
CDK4	DUSP4	0	0	150	288	1	1
CDK4	ACTA1	0	0	81	173	1	1
CDK4	LAG3	0	0	165	165	1	1
CDK4	ANO1	0	0	181	181	1	1
CDK4	DDX39A	0	0	0	284	1	1
CDK4	XRCC3	0	0	156	309	1	1
CDK4	FLII	0	0	95	150	1	1
CDK4	DBF4B	0	0	0	249	1	1
CDK4	EFTUD2	0	0	0	151	1	1
CDK4	RICTOR	0	0	325	339	1	2
CDK4	PIM1	0	0	124	275	1	1
CDK4	ENSG00000261832	0	0	103	198	1	1
CDK4	TEX15	0	900	0	900	1	1
CDK4	ARHGEF28	0	0	0	192	1	1
CDK4	GNAQ	0	0	342	423	1	1
CDK4	CEACAM5	0	0	181	181	1	1
CDK4	RAD18	0	0	57	173	1	1
CDK4	TOP1	180	0	346	474	1	1
CDK4	WWTR1	0	0	142	163	1	1
CDK4	ARHGAP19	0	0	70	168	1	1
CDK4	TUBA3D	0	0	0	236	1	1
CDK4	UBXN7	0	0	0	317	1	1
CDK4	ACP5	0	0	306	321	1	1
CDK4	POLR2G	0	0	0	156	1	1
CDK4	PPP5C	0	0	291	401	1	1
CDK4	FCGR1B	0	0	258	258	1	1
CDK4	FOXN3	0	0	54	189	1	1
CDK4	PPP1R7	0	0	0	185	1	1
CDK4	PPRC1	0	0	112	181	1	1
CDK4	RALGDS	0	0	234	234	1	1
CDK4	RPL35A	0	0	45	156	1	1
CDK4	LGMN	0	0	321	338	1	1
CDK4	MAD2L1	0	0	285	611	1	1
CDK4	LMO3	0	0	0	160	1	1
CDK4	PARK2	0	0	202	202	1	1
CDK4	IFNA1	0	0	218	218	1	1
CDK4	CCNH	0	900	600	974	1	1
CDK4	WNT5A	0	0	252	309	1	2
CDK4	PPP1R16A	0	0	0	151	1	1
CDK4	ILK	0	0	211	312	1	1
CDK4	PURA	0	0	0	181	1	1
CDK4	DDX49	0	0	0	210	1	1
CDK4	CKS2	0	540	234	831	1	1
CDK4	KIF21A	0	0	0	201	1	1
CDK4	PPARGC1A	0	0	234	241	1	2
CDK4	LARP7	270	0	43	284	1	1
CDK4	FOXR2	0	0	86	217	1	1
CDK4	KIF21B	0	0	0	201	1	1
CDK4	HLTF	0	0	0	188	1	1
CDK4	GDPD1	0	0	0	207	1	1
CDK4	CDC14A	0	0	165	403	1	1
CDK4	STK19	0	0	166	184	1	1
CDK4	FGFR2	0	0	423	179	1	1
CDK4	ENO1	0	0	142	270	1	1
CDK4	CYP1A1	0	0	228	227	1	2
CDK4	HDGF	0	0	173	223	1	1
CDK4	ESPL1	0	0	181	493	1	1
CDK4	GREM1	0	0	171	171	1	1
CDK4	ALG1L	0	0	0	180	1	1
CDK4	USP47	0	0	56	203	1	1
CDK4	GAPDH	0	0	662	699	1	2
CDK4	DUSP5	0	0	108	260	1	1
CDK4	TCF7L2	0	0	166	218	1	1
CDK4	HDAC10	0	0	134	190	1	1
CDK4	SMG1	0	0	69	159	1	1
CDK4	FKBP8	0	0	72	157	1	1
CDK4	ABL1	0	900	459	922	1	1
CDK4	POLD2	0	0	76	283	1	1
CDK4	HIST4H4	0	0	274	378	1	1
CDK4	PTBP1	0	0	137	207	1	2
CDK4	TSSK3	0	0	0	254	1	1
CDK4	MAP2K7	0	0	695	379	1	1
CDK4	WIF1	0	0	193	193	1	1
CDK4	PTPN14	0	0	112	203	1	1
CDK4	LRRCC1	0	0	0	185	1	1
CDK4	CCNJ	0	540	71	554	1	1
CDK4	BUB1	0	0	358	625	1	1
CDK4	CIAPIN1	0	0	174	241	1	1
CDK4	FOXB2	0	0	0	178	1	1
CDK4	STAT4	0	0	90	218	1	1
CDK4	ZIC1	0	0	95	153	1	1
CDK4	CASP6	0	0	266	266	1	1
CDK4	TNRC6B	0	650	47	652	1	1
CDK4	KLF6	0	0	211	262	1	1
CDK4	NFKB1	0	0	219	302	1	2
CDK4	KAT6A	0	0	141	182	1	1
CDK4	PLK4	0	0	248	357	1	1
CDK4	DUPD1	0	0	0	193	1	1
CDK4	RELA	270	0	505	623	1	2
CDK4	CDH13	0	0	161	194	1	1
CDK4	CARM1	0	0	144	177	1	2
CDK4	PPP1R12B	0	0	0	151	1	1
CDK4	TPCN1	0	0	150	189	1	1
CDK4	ZDHHC17	0	0	44	389	1	1
CDK4	RPA3	0	600	152	678	1	1
CDK4	CRISP3	0	0	46	164	1	1
CDK4	ZFC3H1	0	0	61	434	1	1
CDK4	RHOJ	0	0	66	164	1	1
CDK4	POLR2A	0	0	113	363	1	1
CDK4	HOPX	0	0	70	186	1	1
CDK4	SIRT2	0	0	261	293	1	2
CDK4	TTC4	0	0	55	183	1	1
CDK4	GRID2IP	0	0	0	260	1	1
CDK4	TRIP12	0	0	70	309	1	1
CDK4	MINPP1	0	0	0	173	1	1
CDK4	IL1RAPL1	0	0	171	301	1	1
CDK4	HSF1	0	0	103	251	1	2
CDK4	IQGAP1	128	0	150	295	1	1
CDK4	AGAP2	0	0	408	426	1	1
CDK4	RECK	0	0	217	217	1	1
CDK4	PFKFB3	0	0	555	572	1	2
CDK4	KIF2B	0	0	0	201	1	1
CDK4	SDHB	0	0	230	229	1	1
CDK4	UBE2D3	0	0	56	151	1	1
CDK4	SRM	0	0	0	173	1	1
CDK4	CLUAP1	270	0	0	270	1	1
CDK4	BIVM-ERCC5	0	0	0	281	1	1
CDK4	CKAP5	0	0	54	272	1	1
CDK4	RHOBTB2	0	0	56	155	1	1
CDK4	CREBBP	0	0	261	319	1	1
CDK4	FOXD4L1	0	0	0	178	1	1
CDK4	MOV10	0	650	45	672	1	1
CDK4	PTGES3L-AARSD1	0	0	0	192	1	1
CDK4	DGCR8	0	0	233	249	1	1
CDK4	APC	189	0	244	374	1	1
CDK4	DBF4	0	0	203	445	1	1
CDK4	HIST2H2AC	0	900	184	921	1	1
CDK4	DHX9	0	0	139	171	1	1
CDK4	ZNFX1	128	0	0	181	1	1
CDK4	CREB1	0	0	375	412	1	2
CDK4	HSFX1	0	0	0	169	1	1
CDK4	MAP3K2	0	0	120	152	1	1
CDK4	MAPRE1	0	0	0	164	1	1
CDK4	PPP4C	0	0	47	273	1	1
CDK4	ACAN	0	0	86	246	1	1
CDK4	ETS2	0	0	215	229	1	1
CDK4	PIK3C3	0	0	141	224	1	2
CDK4	BRWD3	0	0	0	248	1	1
CDK4	CTRL	0	0	275	275	1	2
CDK4	TBL1XR1	0	0	60	263	1	1
CDK4	IGFBP7	0	0	167	167	1	1
CDK4	GNA13	0	0	47	224	1	1
CDK4	SNRPA	0	0	83	240	1	1
CDK4	SRSF9	0	0	60	176	1	1
CDK4	ANKAR	0	0	0	208	1	1
CDK4	CHD1L	0	0	66	180	1	1
CDK4	MPP5	0	0	60	188	1	1
CDK4	ENDOG	0	0	166	185	1	1
CDK4	STAT1	0	0	337	415	1	2
CDK4	SRRM2	0	0	0	374	1	1
CDK4	BCL2L2-PABPN1	0	0	310	344	1	1
CDK4	ELAVL3	0	0	182	190	1	1
CDK4	RAD51C	0	900	369	943	1	1
CDK4	RPP25L	0	0	0	238	1	1
CDK4	PDS5B	0	0	0	164	1	1
CDK4	ENSG00000115239	0	0	75	218	1	1
CDK4	RPL32	0	0	74	150	1	1
CDK4	OCLN	0	0	182	181	1	1
CDK4	PLEK	0	0	181	181	1	1
CDK4	RRAS	0	0	112	217	1	1
CDK4	CYR61	0	0	150	173	1	1
CDK4	CXCR4	0	0	321	321	1	2
CDK4	HIST1H4F	0	0	274	378	1	1
CDK4	MMP1	0	0	218	218	1	1
CDK4	ARAF	187	0	402	340	1	1
CDK4	MTOR	0	0	601	639	1	2
CDK4	MAPKAP1	0	0	154	173	1	1
CDK4	SGOL1	0	0	90	154	1	1
CDK4	RAD51	0	800	368	895	1	2
CDK4	TRIB2	0	0	68	318	1	1
CDK4	E2F2	0	900	746	980	1	1
CDK4	JARID2	0	0	327	332	1	1
CDK4	PSMC6	0	0	166	217	1	1
CDK4	HIST1H1T	0	0	0	252	1	1
CDK4	MSH6	0	0	401	470	1	1
CDK4	CTNNB1	0	0	661	707	1	2
CDK4	ATP6V1B1	0	0	0	154	1	1
CDK4	MYF5	0	0	216	228	1	1
CDK4	HRAS	128	0	952	964	1	2
CDK4	APP	0	0	171	171	1	2
CDK4	MFN2	0	0	108	154	1	2
CDK4	DCAF6	0	0	0	169	1	1
CDK4	EGR1	0	0	310	354	1	2
CDK4	EIF3I	0	0	0	185	1	1
CDK4	MRPL12	0	0	60	201	1	1
CDK4	APOBEC3B	270	0	445	593	1	1
CDK4	KIF3B	0	0	0	201	1	1
CDK4	RHOBTB1	0	0	64	162	1	1
CDK4	ORC1	0	0	88	507	1	1
CDK4	WNT2B	0	0	125	192	1	1
CDK4	PASK	0	0	0	202	1	1
CDK4	ALG1	0	0	0	180	1	1
CDK4	NUSAP1	0	0	67	204	1	1
CDK4	SMC2	0	0	74	287	1	1
CDK4	BAG3	0	0	112	165	1	2
CDK4	ISL1	0	0	112	222	1	1
CDK4	CNOT2	0	0	71	152	1	1
CDK4	NEDD4	0	0	339	355	1	2
CDK4	ORC3	626	0	112	683	1	1
CDK4	FBXL12	0	0	122	254	1	1
CDK4	H1FOO	0	0	0	252	1	1
CDK4	VRK1	0	0	125	312	1	1
CDK4	SUMO2	0	0	112	219	1	1
CDK4	DDX28	0	0	0	175	1	1
CDK4	METTL1	0	0	274	514	1	1
CDK4	NDRG1	0	0	150	174	1	1
CDK4	CXCL8	0	0	335	335	1	2
CDK4	UBE2G1	0	0	0	201	1	1
CDK4	POLR2C	0	0	0	209	1	1
CDK4	KLK3	0	0	338	338	1	1
CDK4	ARF3	0	0	101	245	1	1
CDK4	IL6R	0	0	157	156	1	1
CDK4	KIAA1524	0	0	150	199	1	1
CDK4	TRIB3	0	0	124	237	1	2
CDK4	ENSG00000160201	0	0	166	185	1	1
CDK4	DTYMK	0	0	47	345	1	1
CDK4	CXCL1	0	0	171	171	1	2
CDK4	DMBX1	0	0	0	160	1	1
CDK4	CPSF1	0	0	0	151	1	1
CDK4	MMP14	0	0	211	216	1	1
CDK4	POLA2	0	0	137	298	1	1
CDK4	GNA15	0	0	82	195	1	1
CDK4	POT1	0	0	252	299	1	1
CDK4	PITPNM3	0	0	0	210	1	1
CDK4	HSPA1B	0	0	112	297	1	1
CDK4	PCED1A	0	0	0	158	1	1
CDK4	OS9	0	0	284	328	1	1
CDK4	ATP6V1B2	0	0	0	154	1	1
CDK4	LIMK1	0	0	249	165	1	1
CDK4	KCNH4	0	0	234	234	1	1
CDK4	NFIB	0	0	141	162	1	1
CDK4	DAXX	0	0	247	265	1	1
CDK4	CDC27	0	0	284	567	1	1
CDK4	AFP	0	0	287	306	1	2
CDK4	TUBE1	0	0	0	228	1	1
CDK4	RPSA	0	0	134	183	1	1
CDK4	NQO1	0	0	254	272	1	2
CDK4	EEF1A1	0	0	95	172	1	1
CDK4	VPS29	0	0	0	150	1	1
CDK4	FGF19	0	0	205	205	1	1
CDK4	KAT8	0	0	101	173	1	1
CDK4	GAPVD1	0	0	0	157	1	1
CDK4	QKI	0	0	150	161	1	1
CDK4	KIF2A	0	0	55	213	1	1
CDK4	ALOX5	0	0	125	156	1	1
CDK4	PTPN5	0	0	0	168	1	1
CDK4	PSMA5	0	0	44	197	1	1
CDK4	NOTCH2	0	0	325	362	1	1
CDK4	NCAPG	0	0	76	277	1	1
CDK4	PRMT2	0	0	98	158	1	1
CDK4	CD5	0	0	167	167	1	1
CDK4	CD28	0	0	167	185	1	1
CDK4	COQ5	0	0	0	159	1	1
CDK4	PSMC4	0	0	127	226	1	1
CDK4	GRM1	178	0	74	206	1	1
CDK4	PPIA	0	0	148	208	1	1
CDK4	HELLS	0	0	86	221	1	1
CDK4	TIMELESS	0	0	113	283	1	1
CDK4	COPRS	0	600	49	603	1	1
CDK4	DIRAS3	0	0	166	264	1	2
CDK4	PRCC	0	0	134	205	1	1
CDK4	SFN	0	900	336	935	1	2
CDK4	FABP4	0	900	141	910	1	1
CDK4	BMPR1B	129	0	76	186	1	1
CDK4	CALM2	0	0	56	197	1	1
CDK4	SST	0	0	171	177	1	1
CDK4	PTPN12	0	0	74	197	1	1
CDK4	ALX3	0	0	0	160	1	1
CDK4	ERCC1	0	0	209	239	1	1
CDK4	XRCC5	0	0	242	439	1	1
CDK4	PBRM1	0	650	180	716	1	1
CDK4	ADCK1	0	0	76	176	1	1
CDK4	BLK	0	0	72	197	1	1
CDK4	MEIOB	0	0	0	228	1	1
CDK4	WNT2	0	0	150	215	1	1
CDK4	ENSG00000131152	0	0	0	209	1	1
CDK4	NDUFS8	0	0	0	173	1	1
CDK4	RBL2	128	900	510	974	1	1
CDK4	HIST1H3I	0	0	183	301	1	1
CDK4	DTL	0	0	166	345	1	1
CDK4	KLF2	0	0	201	252	1	1
CDK4	KIF1C	0	0	0	201	1	1
CDK4	HIST2H4A	0	0	274	378	1	1
CDK4	CHUK	0	0	315	212	1	1
CDK4	CUL3	44	0	212	296	1	2
CDK4	PI4KA	0	0	0	197	1	1
CDK4	STK24	0	0	62	189	1	1
CDK4	CHD8	0	0	309	389	1	1
CDK4	HMGB3	0	0	120	186	1	1
CDK4	HCK	0	0	188	243	1	1
CDK4	HIST3H3	0	600	0	658	1	1
CDK4	MEF2A	0	0	140	215	1	1
CDK4	RACGAP1	0	0	96	220	1	1
CDK4	ZRANB3	0	0	0	151	1	1
CDK4	DHFR	0	0	366	419	1	1
CDK4	FBXO5	0	0	248	293	1	1
CDK4	TMEM115	0	0	261	277	1	1
CDK4	NDRG2	0	0	151	150	1	1
CDK4	POLR1A	0	0	47	224	1	1
CDK4	PHB2	0	0	108	232	1	1
CDK4	RRM2	0	0	265	431	1	1
CDK4	PSMD3	0	0	95	167	1	1
CDK4	CSF1	0	0	190	190	1	1
CDK4	HDAC1	217	900	525	965	1	2
CDK4	PRDM1	0	0	193	193	1	1
CDK4	FOS	0	0	468	468	1	2
CDK4	TWIST1	0	0	294	294	1	1
CDK4	YWHAZ	0	0	157	215	1	1
CDK4	DDX24	0	0	0	174	1	1
CDK4	GSC2	0	0	48	166	1	1
CDK4	U2AFBP	0	0	166	185	1	1
CDK4	PTK6	0	600	180	670	1	2
CDK4	ANGPTL4	0	0	102	158	1	1
CDK4	HIST1H2AH	0	900	0	911	1	1
CDK4	DDX31	0	0	0	176	1	1
CDK4	LMO1	0	0	90	203	1	1
CDK4	LMO2	0	0	95	226	1	1
CDK4	MSTN	0	0	142	157	1	1
CDK4	CRKL	0	0	206	216	1	1
CDK4	PDX1	0	0	139	196	1	1
CDK4	RAD1	0	0	95	195	1	1
CDK4	COPS6	53	0	67	221	1	1
CDK4	PTPN11	0	0	299	365	1	1
CDK4	GDPD2	0	0	0	207	1	1
CDK4	NRAS	0	0	631	699	1	1
CDK4	TOP2B	0	0	134	278	1	1
CDK4	E2F1	0	900	832	986	1	2
CDK4	FOXP2	0	0	57	192	1	1
CDK4	HSPA5	0	0	296	372	1	2
CDK4	HIST1H3J	0	0	184	302	1	1
CDK4	SAP25	270	0	0	270	1	1
CDK4	BTRC	0	0	270	282	1	1
CDK4	EIF4A2	0	0	203	316	1	1
CDK4	CAMK4	0	0	61	195	1	1
CDK4	SMYD2	0	0	122	164	1	1
CDK4	DUSP3	0	0	0	193	1	1
CDK4	PGD	111	0	0	154	1	1
CDK4	FOXO1	0	0	463	540	1	2
CDK4	TPTE2	0	0	0	193	1	1
CDK4	SOD2	0	0	183	188	1	2
CDK4	CDK9	0	900	633	918	1	1
CDK4	GALNT1	0	0	75	239	1	1
CDK4	STK38L	0	0	0	335	1	1
CDK4	SDC1	0	0	207	235	1	1
CDK4	FOXI2	0	0	0	178	1	1
CDK4	WEE1	0	0	601	560	1	1
CDK4	PHIP	0	0	0	248	1	1
CDK4	ADCY10	0	0	142	180	1	1
CDK4	SUFU	0	0	202	233	1	1
CDK4	ALDH1A1	0	0	260	260	1	1
CDK4	SFRP2	0	0	150	168	1	1
CDK4	EIF4EBP2	204	0	95	286	1	1
CDK4	RASL11A	0	0	45	158	1	1
CDK4	PIM3	0	0	124	264	1	1
CDK4	PMAIP1	0	0	407	421	1	2
CDK4	PIK3CB	0	0	317	383	1	1
CDK4	CDKN2B	879	900	988	999	1	1
CDK4	LRRK2	270	0	82	390	1	2
CDK4	SKA1	0	0	108	176	1	1
CDK4	GNAO1	0	0	0	210	1	1
CDK4	MET	179	0	519	370	1	2
CDK4	PHB	270	0	150	442	1	1
CDK4	TRAF3	0	0	181	201	1	2
CDK4	PARP2	0	0	125	203	1	1
CDK4	RASL10B	0	0	0	154	1	1
CDK4	DDX43	0	0	0	170	1	1
CDK4	NHP2	0	0	0	276	1	1
CDK4	EIF1AX	128	0	107	206	1	1
CDK4	PSMD9	270	0	0	285	1	1
CDK4	NAB2	0	0	151	150	1	1
CDK4	STK17A	0	0	0	203	1	1
CDK4	CDK5R1	270	0	193	428	1	1
CDK4	CDT1	270	0	509	767	1	1
CDK4	HNRNPAB	0	0	0	211	1	1
CDK4	POLR3K	0	0	0	152	1	1
CDK4	SPC25	0	0	53	152	1	1
CDK4	GNAI3	0	0	0	210	1	2
CDK4	ENSG00000267618	0	0	391	496	1	1
CDK4	TFG	0	0	140	159	1	1
CDK4	RFC5	0	0	74	264	1	1
CDK4	XBP1	0	0	193	193	1	2
CDK4	ASB3	0	0	75	218	1	1
CDK4	SMC1B	0	0	0	265	1	1
CDK4	STAT2	0	0	141	266	1	1
CDK4	SP3	0	0	113	170	1	1
CDK4	TP63	0	0	261	388	1	2
CDK4	SPAG6	0	0	0	210	1	1
CDK4	PCNA	675	900	492	999	1	2
CDK4	GATA6	0	0	182	183	1	1
CDK4	PRKAG2	0	0	0	173	1	1
CDK4	PTPRZ1	0	0	0	168	1	1
CDK4	RAD51D	0	0	391	496	1	1
CDK4	PTPN1	83	0	179	319	1	1
CDK4	FUS	0	0	286	286	1	2
CDK4	CAMK2G	0	0	0	159	1	1
CDK4	PPP5D1	0	0	0	191	1	1
CDK4	PPP2R2C	0	0	0	232	1	1
CDK4	WNT3A	0	0	231	290	1	2
CDK4	DUSP21	0	0	46	186	1	1
CDK4	KCTD19	0	0	0	174	1	1
CDK4	MAP2K6	0	0	171	230	1	1
CDK4	KSR1	270	0	161	399	1	1
CDK4	ATG5	0	0	233	245	1	2
CDK4	ERCC6	0	0	54	161	1	1
CDK4	KCMF1	0	0	0	346	1	1
CDK4	WDR18	0	0	60	299	1	1
CDK4	MAGEA1	0	0	181	181	1	1
CDK4	GNA11	0	0	380	456	1	1
CDK4	SMARCD2	0	650	0	666	1	1
CDK4	TUBB	0	0	123	388	1	1
CDK4	ZNF655	278	0	48	329	1	1
CDK4	ITGAM	0	0	218	218	1	1
CDK4	EIF5A	0	0	54	163	1	2
CDK4	GATA2	270	0	261	438	1	1
CDK4	MAP3K5	178	0	301	257	1	1
CDK4	PSMC5	0	0	53	218	1	1
CDK4	MAPK6	0	0	145	200	1	1
CDK4	PPP1CA	382	0	147	643	1	1
CDK4	RBBP4	0	0	173	313	1	1
CDK4	HMGB1	0	0	107	200	1	2
CDK4	RAC1	0	0	140	230	1	2
CDK4	LYN	131	900	180	927	1	1
CDK4	COPS5	0	0	212	275	1	1
CDK4	GPR149	0	0	0	163	1	1
CDK4	ORC2	0	0	107	488	1	1
CDK4	PDIK1L	0	0	0	220	1	1
CDK4	ACTL6B	0	650	0	671	1	1
CDK4	EHMT1	0	0	0	237	1	1
CDK4	BCOR	0	0	208	208	1	1
CDK4	UBTF	270	0	441	591	1	1
CDK4	TP53BP1	0	0	319	540	1	1
CDK4	SPI1	0	0	165	165	1	1
CDK4	SPAG1	0	0	0	162	1	1
CDK4	CTSB	0	0	145	170	1	2
CDK4	AURKAIP1	0	0	59	244	1	1
CDK4	MCL1	0	0	598	604	1	2
CDK4	HIST1H2AD	0	900	0	908	1	1
CDK4	KIF13B	0	0	0	210	1	1
CDK4	SIRT1	0	0	580	629	1	2
CDK4	SMARCA4	0	650	507	849	1	1
CDK4	RBM10	0	0	127	157	1	1
CDK4	IKBKG	128	0	182	256	1	1
CDK4	RARA	0	0	193	206	1	2
CDK4	GPX1	0	0	117	178	1	1
CDK4	FNIP1	270	0	0	270	1	1
CDK4	KDM5B	0	0	210	216	1	1
CDK4	VTN	129	0	112	193	1	1
CDK4	PSMD14	0	0	124	284	1	1
CDK4	TIAL1	0	0	123	157	1	1
CDK4	RALA	0	0	218	310	1	1
CDK4	AKT3	0	0	466	372	1	2
CDK4	DDX11	0	0	113	182	1	1
CDK4	NEK2	0	0	316	293	1	1
CDK4	LIG1	0	0	122	327	1	1
CDK4	STMN1	0	0	260	295	1	1
CDK4	RPS6KA1	0	0	467	198	1	1
CDK4	STK39	0	0	0	175	1	1
CDK4	LATS1	0	0	234	150	1	1
CDK4	HNRNPK	0	0	138	174	1	1
CDK4	NCAM1	0	0	184	183	1	1
CDK4	NBN	0	0	145	291	1	1
CDK4	RASL10A	0	0	0	154	1	1
CDK4	DACH1	0	0	123	173	1	1
CDK4	PTPRR	0	0	60	184	1	1
CDK4	CHD3	0	0	61	246	1	1
CDK4	MCAM	0	0	95	151	1	1
CDK4	ARID1A	0	650	400	784	1	1
CDK4	DUSP14	0	0	0	198	1	1
CDK4	PTPRH	0	0	0	177	1	1
CDK4	SMG6	0	0	0	164	1	1
CDK4	NFKBIB	0	0	92	222	1	1
CDK4	FOXB1	0	0	0	178	1	1
CDK4	RLBP1	0	0	45	163	1	1
CDK4	DMWD	0	0	0	248	1	1
CDK4	TGFBR1	0	0	293	199	1	1
CDK4	RANBP1	0	0	82	310	1	1
CDK4	ZC3H14	128	0	0	180	1	1
CDK4	S100A4	0	0	170	188	1	1
CDK4	HSPB2	0	0	294	294	1	1
CDK4	ANXA6	0	0	54	197	1	1
CDK4	URGCP	0	0	181	181	1	1
CDK4	HSPB1	0	0	295	295	1	2
CDK4	GLI1	418	0	406	698	1	2
CDK4	ZHX2	0	0	47	194	1	1
CDK4	MTDH	0	0	155	245	1	2
CDK4	CDK7	270	900	838	955	1	1
CDK4	FMN1	0	0	0	247	1	1
CDK4	CHD4	0	0	94	236	1	1
CDK4	GFAP	0	0	234	234	1	2
CDK4	RBPJ	0	0	212	305	1	1
CDK4	COL1A1	0	0	193	210	1	2
CDK4	GMNN	0	0	323	474	1	1
CDK4	GRWD1	0	0	0	150	1	1
CDK4	CDH11	0	0	113	175	1	1
CDK4	ATG7	0	0	233	284	1	2
CDK4	MCM8	0	0	170	364	1	1
CDK4	TJP1	0	0	261	307	1	1
CDK4	TGFBR2	0	0	323	363	1	1
CDK4	EGLN2	270	0	112	362	1	1
CDK4	ACTG1	0	0	288	370	1	1
CDK4	PDS5A	0	0	44	167	1	1
CDK4	RECQL4	270	0	218	543	1	1
CDK4	ORC5	0	0	107	335	1	1
CDK4	BTG2	0	0	252	303	1	1
CDK4	IKZF1	0	0	162	216	1	1
CDK4	LIN9	0	0	253	437	1	1
CDK4	EIF3D	0	0	0	168	1	1
CDK4	G6PD	0	0	135	175	1	1
CDK4	RAD23B	0	0	164	211	1	1
CDK4	MRPL49	0	0	0	180	1	1
CDK4	RET	0	0	458	212	1	1
CDK4	FOXN4	0	0	60	195	1	1
CDK4	POLI	0	0	207	240	1	1
CDK4	ICT1	0	0	66	157	1	1
CDK4	GNAI1	0	0	0	210	1	1
CDK4	CTSD	0	0	134	158	1	2
CDK4	AXIN1	0	0	310	327	1	1
CDK4	BAMBI	0	0	82	192	1	1
CDK4	IDH2	0	0	369	382	1	1
CDK4	EIF3F	0	0	75	177	1	1
CDK4	MRE11A	0	0	288	387	1	1
CDK4	ANKRD61	0	0	0	208	1	1
CDK4	PRKAG3	0	0	0	173	1	1
CDK4	TUBGCP2	0	0	55	169	1	1
CDK4	HIST1H1C	0	0	68	274	1	1
CDK4	SMAD5	0	0	178	207	1	1
CDK4	SHC1	0	0	263	263	1	1
CDK4	POLE2	0	0	108	299	1	1
CDK4	ATM	0	800	635	942	1	2
CDK4	SFRP1	0	0	210	227	1	1
CDK4	ENSG00000258947	0	0	454	560	1	1
CDK4	LMNB2	0	0	174	282	1	1
CDK4	TIMP3	0	0	241	240	1	1
CDK4	MAPK14	129	0	325	362	1	2
CDK4	STK33	0	0	276	269	1	1
CDK4	CFL1	0	0	213	265	1	1
CDK4	NDUFA9	0	0	0	252	1	1
CDK4	RCHY1	0	0	181	254	1	1
CDK4	SREBF1	0	0	202	325	1	1
CDK4	ERCC6L	0	0	0	180	1	1
CDK4	TP53BP2	0	0	128	182	1	2
CDK4	MAPK10	0	0	155	190	1	2
CDK4	HIST1H4A	0	0	276	379	1	1
CDK4	WT1	0	0	298	343	1	1
CDK4	HIST1H3C	0	0	194	311	1	1
CDK4	PTPRG	0	0	0	181	1	1
CDK4	ZBTB33	0	0	57	207	1	1
CDK4	TCF4	0	0	181	181	1	1
CDK4	BMP4	0	0	245	246	1	1
CDK4	COX8A	0	0	143	166	1	1
CDK4	ATAD2B	0	0	0	236	1	1
CDK4	LEP	0	0	190	190	1	1
CDK4	SYK	0	0	245	167	1	2
CDK4	NFKBIA	0	0	396	460	1	2
CDK4	HFE	0	0	0	180	1	1
CDK4	AIMP2	0	0	0	195	1	1
CDK4	PRAME	0	0	181	201	1	1
CDK4	MSH3	0	0	171	222	1	1
CDK4	PI4KB	0	0	60	163	1	1
CDK4	MYOD1	486	0	690	839	1	1
CDK4	TRAF7	0	0	76	259	1	1
CDK4	SRCAP	0	0	0	200	1	1
CDK4	RPS20	0	0	82	184	1	1
CDK4	PRKAA2	0	0	60	236	1	2
CDK4	RSF1	0	0	82	441	1	1
CDK4	HIST1H3A	0	0	187	305	1	1
CDK4	GLIPR1	0	0	67	433	1	1
CDK4	MAPK7	0	0	234	210	1	1
CDK4	IRF4	0	0	207	349	1	1
CDK4	ARID2	0	650	310	753	1	1
CDK4	VEGFA	0	0	565	616	1	2
CDK4	GINS2	0	0	216	369	1	1
CDK4	PTEN	165	0	706	828	1	2
CDK4	NEK7	0	0	57	232	1	1
CDK4	ID3	0	0	171	190	1	1
CDK4	MBP	0	0	134	152	1	2
CDK4	RUNX1	0	0	108	200	1	2
CDK4	TSSK2	0	0	0	261	1	1
CDK4	HINT2	0	0	0	161	1	1
CDK4	CENPK	0	0	0	180	1	1
CDK4	SAV1	0	0	154	153	1	1
CDK4	CYC1	0	0	0	160	1	1
CDK4	INF2	0	0	0	228	1	1
CDK4	FANCI	0	0	141	230	1	1
CDK4	PECAM1	0	0	366	366	1	1
CDK4	CCNK	0	720	454	886	1	1
CDK4	ANK2	0	0	0	208	1	1
CDK4	ARID4A	270	0	81	398	1	1
CDK4	UBB	0	0	123	173	1	1
CDK4	NDC80	0	0	200	394	1	1
CDK4	NKX2-5	0	0	107	156	1	1
CDK4	INADL	0	0	75	251	1	1
CDK4	LRP6	0	0	142	229	1	1
CDK4	DNAJB7	0	0	170	189	1	1
CDK4	MCM10	0	0	166	385	1	1
CDK4	SNRPA1	0	0	0	166	1	1
CDK4	CCNE1	442	900	753	995	1	1
CDK4	FOXP4	0	0	0	178	1	1
CDK4	ERH	0	0	112	187	1	1
CDK4	TXN	0	0	170	218	1	1
CDK4	CFAP44	0	0	0	248	1	1
CDK4	PHLPP2	0	0	155	260	1	1
CDK4	ANXA7	47	0	44	161	1	1
CDK4	MDK	0	0	95	476	1	1
CDK4	HIST2H4B	0	0	275	378	1	1
CDK4	PPP2R5E	0	0	54	187	1	1
CDK4	MAP2K2	0	0	359	336	1	1
CDK4	PITPNM2	0	0	0	210	1	1
CDK4	CD38	0	0	166	165	1	2
CDK4	CDX4	0	0	0	176	1	1
CDK4	TNRC6A	0	650	48	652	1	1
CDK4	RHEB	0	0	251	347	1	2
CDK4	KIF23	0	0	75	317	1	1
CDK4	AHCY	0	0	93	210	1	1
CDK4	HINFP	0	0	90	171	1	1
CDK4	KIAA1875	0	0	0	158	1	1
CDK4	DLGAP3	0	0	0	192	1	1
CDK4	EML1	0	0	46	252	1	1
CDK4	EFNA1	0	0	81	222	1	1
CDK4	NADSYN1	0	0	66	567	1	1
CDK4	CAPRIN1	0	0	66	206	1	1
CDK4	E2F8	0	0	702	764	1	1
CDK4	SNRPC	0	0	0	171	1	1
CDK4	SNRPF	0	0	53	200	1	1
CDK4	GNB2L1	0	0	108	218	1	1
CDK4	PTPLAD2	0	0	66	157	1	1
CDK4	DFFA	0	0	165	186	1	1
CDK4	TUBA1A	0	0	81	268	1	1
CDK4	TACC3	0	0	261	323	1	1
CDK4	ACTA2	0	0	74	176	1	1
CDK4	NOS3	0	0	205	222	1	2
CDK4	PPIP5K2	0	0	0	254	1	1
CDK4	RRM2B	0	0	134	266	1	1
CDK4	JUND	0	0	430	568	1	1
CDK4	PRKAA1	0	0	90	239	1	2
CDK4	LRGUK	0	0	0	283	1	1
CDK4	FLI1	0	0	124	157	1	1
CDK4	RPRM	105	0	181	235	1	1
CDK4	MEIS1	0	0	166	191	1	1
CDK4	CCND1	998	900	990	999	1	2
CDK4	ZNF101	128	0	0	184	1	1
CDK4	UBE2I	0	0	108	250	1	1
CDK4	SORBS1	151	0	46	173	1	1
CDK4	WDR77	270	600	237	820	1	1
CDK4	WNT9A	0	0	134	255	1	1
CDK4	CD19	0	0	218	235	1	1
CDK4	IFIT2	0	0	70	165	1	1
CDK4	MED13L	0	0	0	157	1	1
CDK4	ANXA2	0	0	142	221	1	1
CDK4	NCF1	0	0	96	194	1	1
CDK4	TOPBP1	0	0	150	299	1	1
CDK4	DDX23	0	0	0	174	1	1
CDK4	PIK3C2B	0	0	256	328	1	1
CDK4	STYXL1	0	0	0	193	1	1
CDK4	RRAD	0	0	72	200	1	1
CDK4	GINS3	0	0	60	362	1	1
CDK4	WDR37	0	0	0	248	1	1
CDK4	WDR86	0	0	0	184	1	1
CDK4	PAK6	0	0	81	196	1	1
CDK4	EIF4E	0	0	344	358	1	2
CDK4	PPP2CA	0	0	150	313	1	1
CDK4	PRKDC	129	0	324	461	1	2
CDK4	HIST2H2BE	0	600	194	681	1	1
CDK4	ETV6	0	0	194	194	1	1
CDK4	BAD	0	0	135	181	1	2
CDK4	RFWD2	0	0	0	248	1	1
CDK4	OLIG2	0	0	258	258	1	1
CDK4	MCMBP	0	0	70	155	1	1
CDK4	YWHAQ	0	0	70	177	1	1
CDK4	HEY1	0	0	194	212	1	1
CDK4	PRRX2	0	0	0	160	1	1
CDK4	DMTF1	0	0	487	568	1	1
CDK4	KAT2B	0	0	285	336	1	1
CDK4	MOB1B	0	0	0	214	1	1
CDK4	CCDC132	0	0	0	339	1	1
CDK4	CCND3	981	900	989	999	1	1
CDK4	RFXANK	0	0	0	183	1	1
CDK4	SOCS1	0	0	211	247	1	1
CDK4	KNSTRN	0	0	160	206	1	1
CDK4	BTK	0	0	325	202	1	1
CDK4	MAPK1	274	0	401	465	1	2
CDK4	CSNK1G3	0	0	0	173	1	1
CDK4	ANAPC2	0	0	249	365	1	1
CDK4	HIST1H3H	0	0	184	302	1	1
CDK4	PPP2R1A	232	0	180	375	1	1
CDK4	UBE2Z	0	0	0	150	1	1
CDK4	IGF1	0	0	468	468	1	2
CDK4	SHOX2	128	0	54	247	1	1
CDK4	MUS81	0	0	52	304	1	1
CDK4	PPP2R5C	0	0	112	237	1	1
CDK4	TUBGCP6	0	0	0	181	1	1
CDK4	ESRRB	0	0	139	156	1	1
CDK4	PKM	45	0	246	324	1	1
CDK4	LRRC10	0	0	55	294	1	1
CDK4	GADD45A	0	900	469	945	1	1
CDK4	CCT2	0	0	106	495	1	1
CDK4	CDK17	0	0	228	174	1	1
CDK4	BCL2A1	0	0	243	254	1	1
CDK4	KIFC3	0	0	0	244	1	1
CDK4	GINS4	0	0	0	169	1	1
CDK4	KMT2A	0	0	146	201	1	1
CDK4	FGF2	0	0	459	459	1	2
CDK4	PRDX4	0	0	73	175	1	1
CDK4	GEN1	0	0	54	260	1	1
CDK4	LRRC61	0	0	0	185	1	1
CDK4	PPEF2	0	0	0	172	1	1
CDK4	RELB	0	0	228	227	1	2
CDK4	FOXK2	0	0	108	236	1	1
CDK4	ITSN2	0	0	0	199	1	1
CDK4	PPTC7	0	0	0	175	1	1
CDK4	SOS1	0	0	193	298	1	1
CDK4	BYSL	0	0	0	161	1	1
CDK4	AXIN2	0	0	255	272	1	1
CDK4	ENTHD2	0	0	0	151	1	1
CDK4	POTEI	0	0	0	174	1	1
CDK4	PTCH1	0	0	342	342	1	1
CDK4	PEX10	0	0	0	184	1	1
CDK4	CUL4B	43	0	143	279	1	1
CDK4	SPRY2	0	0	141	175	1	1
CDK4	HIST1H4H	0	0	275	378	1	1
CDK4	CCNT2	0	900	82	925	1	1
CDK4	RPLP0	0	0	150	260	1	1
CDK4	DDX3X	0	0	150	297	1	1
CDK4	C11orf30	0	0	147	206	1	1
CDK4	ACVR2A	0	0	134	185	1	1
CDK4	TSSK1B	0	0	0	266	1	1
CDK4	TRNP1	0	0	212	295	1	1
CDK4	ATP11B	0	0	112	154	1	1
CDK4	GLS2	0	0	134	153	1	1
CDK4	SHPRH	0	0	47	155	1	1
CDK4	MMP7	0	0	264	269	1	1
CDK4	FOXR1	0	0	54	189	1	1
CDK4	MUTYH	0	0	342	358	1	1
CDK4	NME1	0	0	206	437	1	1
CDK4	VCL	0	0	215	233	1	1
CDK4	OGFRL1	375	0	0	375	1	1
CDK4	DUSP26	0	0	0	193	1	1
CDK4	CASP2	0	0	261	297	1	1
CDK4	GNAI2	0	0	48	216	1	1
CDK4	DAAM2	0	0	0	228	1	1
CDK4	MYBBP1A	0	0	0	164	1	1
CDK4	DDX51	0	0	0	198	1	1
CDK4	IL7	0	0	155	154	1	1
CDK4	TJP2	0	0	137	186	1	1
CDK4	POLR1C	0	0	0	280	1	1
CDK4	CD44	178	0	401	497	1	2
CDK4	SLC1A5	0	0	134	185	1	1
CDK4	BDNF	0	0	149	167	1	2
CDK4	LIG4	0	0	90	252	1	1
CDK4	HSPA13	0	0	0	158	1	1
CDK4	TUBB4B	0	0	0	253	1	1
CDK4	HSPA2	0	0	55	176	1	1
CDK4	MYF6	0	0	186	198	1	1
CDK4	TIPIN	0	0	106	266	1	1
CDK4	NUCKS1	0	0	102	256	1	1
CDK4	RHAG	0	0	155	154	1	1
CDK4	CDK12	0	720	369	779	1	1
CDK4	LHX9	0	0	0	163	1	1
CDK4	PRDM5	0	0	55	177	1	1
CDK4	CELF1	0	0	321	335	1	1
CDK4	HNRNPD	0	0	149	208	1	1
CDK4	YBX1	0	0	223	308	1	1
CDK4	SMARCD1	0	650	0	657	1	1
CDK4	EDF1	0	0	0	151	1	1
CDK4	MRPS34	274	0	0	340	1	1
CDK4	KMT2D	0	0	302	337	1	1
CDK4	PSMD5	0	0	150	188	1	1
CDK4	E2F4	169	900	769	986	1	1
CDK4	FBXL14	0	0	107	197	1	1
CDK4	ARF4	0	0	58	152	1	1
CDK4	ING1	0	0	181	242	1	1
CDK4	NOX4	0	0	162	172	1	2
CDK4	SPATA5L1	0	0	0	164	1	1
CDK4	DROSHA	0	0	288	329	1	1
CDK4	TNKS2	0	0	54	219	1	1
CDK4	CLDN1	0	0	148	171	1	1
CDK4	SSH2	0	0	0	193	1	1
CDK4	PHKG1	0	0	72	219	1	1
CDK4	CD247	0	0	156	155	1	1
CDK4	AARS2	0	0	0	276	1	1
CDK4	MZF1	128	0	73	211	1	1
CDK4	CDK8	0	900	468	922	1	1
CDK4	PSMD8	0	0	51	253	1	1
CDK4	WDTC1	0	0	0	199	1	1
CDK4	FAN1	0	0	0	156	1	1
CDK4	IFIT3	0	0	75	169	1	1
CDK4	VCAM1	0	0	155	154	1	1
CDK4	UQCRFS1	0	0	0	212	1	1
CDK4	CDK18	0	0	292	181	1	1
CDK4	SUMO1	0	0	174	258	1	1
CDK4	FAS	0	0	269	269	1	2
CDK4	CSF2	0	0	252	252	1	1
CDK4	DRGX	0	0	0	160	1	1
CDK4	PREX2	0	0	136	190	1	1
CDK4	CTDP1	0	0	46	193	1	1
CDK4	WEE2	0	0	53	509	1	1
CDK4	DDX10	0	0	0	166	1	1
CDK4	DYSF	0	0	81	152	1	1
CDK4	WDR20	0	0	0	248	1	1
CDK4	HIST1H4C	0	0	274	378	1	1
CDK4	RASD2	0	0	0	154	1	1
CDK4	DNAL1	0	0	0	185	1	1
CDK4	RHD	0	0	275	276	1	1
CDK4	DENR	0	0	0	195	1	1
CDK4	ACVR1B	0	0	155	241	1	1
CDK4	FUBP1	0	0	202	241	1	1
CDK4	AGO3	0	650	0	664	1	1
CDK4	NGF	0	0	267	267	1	2
CDK4	CSNK2A3	0	0	0	179	1	1
CDK4	CD34	0	0	420	420	1	2
CDK4	TUBAL3	0	0	0	236	1	1
CDK4	DNAAF1	0	0	0	185	1	1
CDK4	FOXJ1	0	0	75	207	1	1
CDK4	SBK2	0	0	0	286	1	1
CDK4	FOXF1	0	0	81	213	1	1
CDK4	STC2	0	0	73	202	1	1
CDK4	CHTF18	0	0	0	207	1	1
CDK4	HIST1H2BN	0	600	0	621	1	1
CDK4	FOXQ1	0	0	125	250	1	1
CDK4	ANKRA2	270	0	0	362	1	1
CDK4	SMC6	0	0	72	289	1	1
CDK4	MGAM	0	0	270	270	1	1
CDK4	AIFM1	0	0	73	178	1	1
CDK4	MRPL9	0	0	0	157	1	1
CDK4	PMS2	0	0	391	433	1	1
CDK4	KRT18	0	0	208	236	1	1
CDK4	XAB2	0	0	74	150	1	1
CDK4	EIF4EBP1	0	0	467	510	1	2
CDK4	ANKRD65	0	0	0	208	1	1
CDK4	POLA1	0	0	185	433	1	1
CDK4	TYMS	0	0	334	484	1	1
CDK4	GP2	0	0	57	151	1	1
CDK4	DDX56	0	0	74	232	1	1
CDK4	PTPN23	0	0	0	199	1	1
CDK4	AXL	0	0	362	207	1	2
CDK4	FOXO4	0	0	260	366	1	1
CDK4	EP400NL	0	0	0	236	1	1
CDK4	HSP90AB1	892	0	123	971	1	2
CDK4	CEP63	0	0	0	207	1	1
CDK4	BCL6	0	0	257	305	1	1
CDK4	FOXH1	0	0	47	183	1	1
CDK4	PPP3CA	0	0	351	457	1	1
CDK4	GJA1	0	0	209	209	1	1
CDK4	GPT	0	0	193	219	1	1
CDK4	INO80	0	0	0	157	1	1
CDK4	SSRP1	0	0	0	258	1	1
CDK4	PHGDH	0	0	202	271	1	1
CDK4	SSR2	0	0	60	184	1	1
CDK4	HMGA1	0	0	126	177	1	1
CDK4	EWSR1	0	0	387	400	1	1
CDK4	TP53INP1	0	0	195	195	1	2
CDK4	RNF139	0	0	66	174	1	1
CDK4	HNF4A	0	0	520	520	1	1
CDK4	CASKIN1	0	0	0	166	1	1
CDK4	TERF2IP	0	0	407	407	1	1
CDK4	MCRS1	0	0	124	178	1	1
CDK4	ARHGAP27	0	0	0	230	1	1
CDK4	PSMD7	0	0	0	155	1	1
CDK4	EID2	0	0	357	357	1	1
CDK4	CDKN3	0	0	969	975	1	1
CDK4	BIRC6	0	0	127	252	1	1
CDK4	TRIM28	270	0	100	459	1	2
CDK4	GMPS	0	0	0	160	1	1
CDK4	ANKRD17	0	0	62	165	1	1
CDK4	CORO1A	0	0	0	322	1	1
CDK4	RPE65	0	0	0	160	1	1
CDK4	ORC6	0	0	166	221	1	1
CDK4	HARS2	0	0	0	175	1	1
CDK4	FBXW9	0	0	0	204	1	1
CDK4	ATG3	0	0	96	171	1	2
CDK4	DNAJB1	0	0	231	244	1	2
CDK4	MIF	0	0	106	216	1	2
CDK4	CAMK2D	0	0	49	160	1	1
CDK4	SIN3B	270	0	108	412	1	1
CDK4	CDC42	0	0	341	418	1	2
CDK4	EIF6	0	0	0	152	1	1
CDK4	C1QBP	0	0	54	203	1	1
CDK4	DKC1	0	0	88	154	1	1
CDK4	DKK1	0	0	212	212	1	1
CDK4	MPHOSPH8	0	0	0	176	1	1
CDK4	IRF8	157	0	74	186	1	1
CDK4	CCNO	0	540	0	685	1	1
CDK4	PKMYT1	0	0	194	539	1	1
CDK4	FMNL1	0	0	0	232	1	1
CDK4	CBFB	0	900	62	904	1	1
CDK4	SLC2A4	0	0	171	189	1	1
CDK4	VDAC3	0	0	57	157	1	1
CDK4	FOXO3	0	0	468	557	1	2
CDK4	ITGA6	0	0	193	193	1	1
CDK4	BGLAP	0	0	180	179	1	1
CDK4	XRCC6BP1	0	0	234	331	1	1
CDK4	CCT3	0	0	45	344	1	1
CDK4	TNFSF11	0	0	184	183	1	2
CDK4	POLB	0	0	134	166	1	1
CDK4	TEP1	0	0	0	285	1	1
CDK4	PITPNB	0	0	0	210	1	1
CDK4	USP7	0	0	154	179	1	1
CDK4	PRKCD	0	0	265	160	1	2
CDK4	ZWINT	0	0	0	170	1	1
CDK4	FOXD2	0	0	0	178	1	1
CDK4	MRPS2	0	0	0	158	1	1
CDK4	RIPK3	0	0	46	189	1	2
CDK4	ZCCHC13	0	0	103	159	1	1
CDK4	ENSG00000259316	0	0	0	173	1	1
CDK4	STAT5B	0	0	370	520	1	1
CDK4	RASGRF2	0	0	0	165	1	1
CDK4	DDX59	0	0	0	163	1	1
CDK4	PIK3C2A	0	0	105	191	1	1
CDK4	DDB1	0	0	185	291	1	1
CDK4	RAX	0	0	0	160	1	1
CDK4	MRPL16	0	0	59	192	1	1
CDK4	DIS3	0	0	66	155	1	1
CDK4	VDAC1	0	0	102	196	1	2
CDK4	KRT19	0	0	201	201	1	1
CDK4	GADD45G	0	0	154	153	1	1
CDK4	TGFB1	0	0	290	321	1	2
CDK4	RASSF5	0	0	96	211	1	1
CDK4	DDX20	0	0	54	182	1	1
CDK4	TIAM1	0	0	130	184	1	1
CDK4	TAF5L	0	0	0	248	1	1
CDK4	ALG2	0	0	0	180	1	1
CDK4	MAGOH	0	0	112	246	1	1
CDK4	ISX	0	0	0	160	1	1
CDK4	TDRD12	0	0	0	163	1	1
CDK4	HIST1H2BJ	0	600	0	621	1	1
CDK4	PRMT5	270	600	304	873	1	1
CDK4	SKP1	187	650	370	821	1	2
CDK4	KDR	0	0	455	208	1	2
CDK4	RNF2	0	0	134	169	1	1
CDK4	HMMR	0	0	150	218	1	1
CDK4	YY1	0	0	293	338	1	1
CDK4	RAC2	0	0	134	225	1	1
CDK4	NKX3-1	0	0	150	178	1	1
CDK4	RPL11	0	0	97	154	1	1
CDK4	DDX39B	0	0	49	197	1	1
CDK4	TUBB2A	0	0	113	287	1	1
CDK4	HIST1H4D	0	0	274	378	1	1
CDK4	FOXP3	0	0	212	330	1	2
CDK4	PTPN6	0	0	92	178	1	1
CDK4	MGST1	0	0	0	536	1	1
CDK4	PRIM2	0	0	57	192	1	1
CDK4	H2AFJ	0	900	0	911	1	1
CDK4	MTFP1	118	0	0	167	1	1
CDK4	SP7	0	0	108	184	1	1
CDK4	MYO9A	0	0	0	155	1	1
CDK4	NPAT	0	0	181	181	1	1
CDK4	HPGDS	0	0	282	291	1	1
CDK4	FBXW7	0	0	456	537	1	2
CDK4	IL3	0	0	219	219	1	1
CDK4	FOSL1	0	0	310	330	1	1
CDK4	KIF5A	0	0	66	241	1	1
CDK4	SETDB1	62	0	142	201	1	1
CDK4	PAX8	0	0	161	175	1	1
CDK4	TBL2	0	0	0	248	1	1
CDK4	SPDYA	0	0	125	171	1	1
CDK4	CCP110	0	0	124	205	1	1
CDK4	COX4I1	0	0	150	168	1	1
CDK4	SUV39H1	0	900	206	924	1	1
CDK4	RPL22	0	0	135	182	1	1
CDK4	DCTPP1	0	0	0	233	1	1
CDK4	NEUROD1	0	0	219	219	1	1
CDK4	ALX4	0	0	0	160	1	1
CDK4	SFI1	0	0	0	254	1	1
CDK4	WRN	0	0	216	428	1	1
CDK4	KIF13A	0	0	0	210	1	1
CDK4	PATZ1	0	0	71	162	1	1
CDK4	HTRA2	0	0	123	150	1	1
CDK4	CEBPA	675	800	819	990	1	1
CDK4	SETD1A	0	0	107	202	1	1
CDK4	TCEAL1	0	0	90	159	1	1
CDK4	CD40	0	0	210	221	1	2
CDK4	CTTN	0	0	165	183	1	1
CDK4	STUB1	429	0	282	599	1	2
CDK4	DPRX	0	0	0	160	1	1
CDK4	DNMT1	0	0	452	494	1	2
CDK4	GTSE1	0	0	137	189	1	1
CDK4	INS	0	0	510	514	1	2
CDK4	GAS6	0	0	158	157	1	1
CDK4	FOXJ3	0	0	0	178	1	1
CDK4	AK2	274	0	0	360	1	1
CDK4	ACTB	0	0	681	731	1	2
CDK4	TUBGCP3	0	0	0	181	1	1
CDK4	ZCCHC11	0	0	107	171	1	1
CDK4	FOXG1	0	0	91	231	1	1
CDK4	POLR2H	0	0	0	177	1	1
CDK4	HIST1H4J	0	0	275	378	1	1
CDK4	GLI3	0	0	204	333	1	1
CDK4	FAT3	0	0	145	172	1	1
CDK4	HSFX2	0	0	0	169	1	1
CDK4	LRRIQ1	0	0	0	185	1	1
CDK4	MPND	0	0	0	164	1	1
CDK4	ARID4B	0	0	0	175	1	1
CDK4	LRRIQ3	0	0	0	185	1	1
CDK4	KEAP1	0	0	294	294	1	2
CDK4	PAX5	0	0	218	231	1	1
CDK4	HSPE1	0	0	66	152	1	1
CDK4	B2M	0	0	235	235	1	1
CDK4	ROS1	0	0	392	215	1	1
CDK4	ANLN	0	0	92	180	1	1
CDK4	ANGPT1	0	0	162	161	1	1
CDK4	KMT2C	0	0	262	299	1	1
CDK4	PROM1	0	0	359	363	1	2
CDK4	SETSIP	0	0	0	228	1	1
CDK4	CSNK1E	0	0	83	417	1	1
CDK4	SIRT3	0	0	213	247	1	2
CDK4	BRCC3	0	0	0	164	1	1
CDK4	MCM5	0	0	341	650	1	1
CDK4	GSR	0	0	123	155	1	1
CDK4	ETV4	0	0	205	243	1	1
CDK4	SPO11	0	650	0	739	1	1
CDK4	HSPA8	270	0	593	744	1	2
CDK4	EIF4G1	0	0	203	276	1	2
CDK4	EPCAM	0	0	322	336	1	2
CDK4	MBD3	0	0	47	225	1	1
CDK4	RHOA	0	0	373	466	1	2
CDK4	ABTB1	0	0	0	150	1	1
CDK4	PARP1	0	0	372	546	1	2
CDK4	NKRF	0	0	113	170	1	1
CDK4	ERAS	0	0	53	165	1	1
CDK4	GTF3A	0	0	0	175	1	1
CDK4	GABPB1	0	0	67	183	1	1
CDK4	UBE2N	0	0	70	195	1	1
CDK4	FGF4	0	0	228	227	1	1
CDK4	RHOQ	0	0	81	178	1	1
CDK4	HIST1H1D	270	0	0	431	1	1
CDK4	RNF43	0	0	193	210	1	1
CDK4	CXCL12	0	0	271	271	1	2
CDK4	TPM1	0	0	141	158	1	1
CDK4	TOMM40	0	0	0	159	1	1
CDK4	HIST1H2BL	0	600	0	621	1	1
CDK4	KDM1A	0	0	284	336	1	2
CDK4	GTF2H1	0	0	123	153	1	2
CDK4	PIWIL1	0	0	171	177	1	1
CDK4	TARDBP	270	0	0	325	1	2
CDK4	FEN1	0	0	195	448	1	1
CDK4	ESR2	0	0	341	351	1	1
CDK4	STK4	0	0	74	261	1	1
CDK4	RHOG	0	0	61	160	1	1
CDK4	NIM1K	0	0	46	259	1	1
CDK4	CLNS1A	0	0	0	153	1	1
CDK4	LRRC56	0	0	0	185	1	1
CDK4	CYP2R1	0	0	49	348	1	1
CDK4	FOXD3	0	0	108	236	1	1
CDK4	PBX1	0	0	142	160	1	1
CDK4	PDK2	0	0	66	155	1	1
CDK4	NOP56	0	0	0	209	1	1
CDK4	WDR38	0	0	0	277	1	1
CDK4	TUBA1B	0	0	73	315	1	1
CDK4	OCA2	0	0	181	361	1	1
CDK4	CCT4	0	0	0	202	1	1
CDK4	ADSL	0	0	0	193	1	1
CDK4	SIRT7	0	0	193	242	1	2
CDK4	ZEB1	0	0	427	426	1	2
CDK4	CD24	0	0	234	255	1	2
CDK4	CTAG1B	0	0	232	231	1	1
CDK4	MXI1	0	0	143	205	1	1
CDK4	H1FX	0	0	57	265	1	1
CDK4	ELP3	0	0	0	164	1	1
CDK4	BORCS8-MEF2B	0	0	97	176	1	1
CDK4	GRN	0	0	107	171	1	1
CDK4	ZBTB38	0	0	0	195	1	1
CDK4	ANK1	0	0	49	215	1	1
CDK4	NKX2-2	0	0	142	156	1	1
CDK4	STOML2	0	0	0	210	1	1
CDK4	WDFY2	0	0	94	326	1	1
CDK4	SPOP	270	0	310	486	1	1
CDK4	YWHAE	0	0	125	185	1	1
CDK4	SNAPC4	0	0	0	194	1	1
CDK4	VCP	113	0	66	266	1	2
CDK4	LCK	0	0	261	270	1	1
CDK4	CD69	0	0	140	193	1	1
CDK4	MIB2	0	0	0	150	1	1
CDK4	DNA2	0	0	66	275	1	1
CDK4	GTPBP4	0	0	100	292	1	1
CDK4	CABLES1	0	0	74	185	1	1
CDK4	MED12	0	0	218	253	1	1
CDK4	DUSP22	0	0	0	193	1	1
CDK4	ATAD2	0	0	89	176	1	1
CDK4	SMYD3	0	0	107	150	1	1
CDK4	SHH	0	0	503	556	1	2
CDK4	CSNK1A1	0	0	210	371	1	1
CDK4	ALX1	0	0	45	164	1	1
CDK4	PRDX1	0	0	76	169	1	1
CDK4	EIF1	0	0	53	216	1	1
CDK4	STYX	0	0	0	193	1	1
CDK4	CAMK1D	0	0	112	246	1	1
CDK4	HAVCR2	0	0	167	167	1	1
CDK4	FANCA	0	0	208	231	1	1
CDK4	ARID1B	0	650	213	716	1	1
CDK4	DLL1	0	0	212	212	1	1
CDK4	CSTF3	105	0	0	172	1	1
CDK4	TM2D2	0	0	61	160	1	1
CDK4	IGFBP3	0	0	275	275	1	2
CDK4	BIK	0	0	134	152	1	2
CDK4	CALR	0	0	180	228	1	1
CDK4	GALK2	0	0	0	170	1	1
CDK4	ISL2	0	0	0	160	1	1
CDK4	RPA2	270	600	81	791	1	1
CDK4	CD8A	0	0	370	370	1	1
CDK4	MNAT1	0	900	139	925	1	1
CDK4	WDFY1	0	0	0	248	1	1
CDK4	SAE1	0	0	82	262	1	1
CDK4	CRK	0	0	134	151	1	1
CDK4	ETV1	0	0	204	204	1	1
CDK4	IL1RAPL2	0	0	0	192	1	1
CDK4	TFAM	0	0	113	184	1	2
CDK4	LIMK2	135	0	134	207	1	1
CDK4	UHRF2	128	0	58	172	1	1
CDK4	TOB1	0	0	123	155	1	1
CDK4	RASD1	0	0	94	201	1	1
CDK4	ATP5B	70	0	74	172	1	1
CDK4	NEK3	0	0	48	156	1	1
CDK4	PNCK	0	0	66	237	1	1
CDK4	MMP2	0	0	503	503	1	2
CDK4	FZR1	129	0	260	637	1	1
CDK4	HIST2H3C	0	0	0	180	1	1
CDK4	IGF2BP3	0	0	94	154	1	1
CDK4	SS18	0	0	182	199	1	1
CDK4	ZBTB17	0	0	95	153	1	1
CDK4	ECT2L	0	0	0	271	1	1
CDK4	DNAJC9	171	0	59	354	1	1
CDK4	CHEK1	0	0	603	528	1	2
CDK4	MTBP	0	0	74	163	1	1
CDK4	CASP1	0	0	166	165	1	2
CDK4	AKT1S1	0	0	245	244	1	1
CDK4	DEDD	0	0	134	225	1	1
CDK4	HSPA1A	0	0	235	394	1	1
CDK4	RFC2	0	0	150	264	1	1
CDK4	SRF	0	0	164	295	1	1
CDK4	MST4	0	0	45	189	1	1
CDK4	CAV1	0	0	267	267	1	2
CDK4	TNFSF10	0	0	275	275	1	2
CDK4	PROP1	0	0	0	160	1	1
CDK4	MAP2K3	145	0	411	378	1	1
CDK4	ENSG00000268434	0	0	0	323	1	1
CDK4	CDC20	0	0	459	706	1	1
CDK4	PLK5	0	0	57	330	1	1
CDK4	APPBP2	0	0	0	164	1	1
CDK4	VRK2	0	0	0	227	1	1
CDK4	ARL17B	0	0	0	194	1	1
CDK4	HNRNPA1	0	0	139	219	1	1
CDK4	KPNB1	0	0	73	173	1	1
CDK4	TNKS	0	0	107	262	1	1
CDK4	KIF11	0	0	218	504	1	1
CDK4	CEP135	71	0	274	341	1	1
CDK4	KPNA6	0	0	0	210	1	1
CDK4	FBXO4	270	0	510	627	1	1
CDK4	TSC1	129	0	166	263	1	2
CDK4	BCL2L11	0	0	519	523	1	2
CDK4	PPP1R16B	0	0	0	151	1	1
CDK4	FSCN1	0	0	134	152	1	1
CDK4	WDR33	128	0	0	316	1	1
CDK4	WDR5	0	0	155	235	1	1
CDK4	MAPK12	0	0	150	267	1	1
CDK4	BRD3	0	0	143	199	1	1
CDK4	MPP4	0	0	0	159	1	1
CDK4	NR2F2	0	0	161	174	1	1
CDK4	PLCG1	0	0	207	224	1	1
CDK4	DCAF10	0	0	0	227	1	1
CDK4	AURKC	0	0	167	399	1	1
CDK4	RPL7	0	0	82	159	1	1
CDK4	SAC3D1	0	0	96	189	1	1
CDK4	CSE1L	0	0	57	205	1	1
CDK4	TRIP13	0	0	0	188	1	1
CDK4	LIF	0	0	157	156	1	2
CDK4	STK16	0	0	0	176	1	1
CDK4	PMEL	0	0	298	315	1	1
CDK4	TYR	0	0	420	420	1	2
CDK4	POTEJ	0	0	0	174	1	1
CDK4	PGRMC1	270	0	47	274	1	1
CDK4	PPIB	0	0	46	160	1	1
CDK4	SNRPD2	0	0	0	218	1	1
CDK4	CDKN1C	486	600	710	950	1	1
CDK4	RABL6	0	0	125	173	1	1
CDK4	DAB2	0	0	122	154	1	1
CDK4	DLG5	0	0	0	172	1	1
CDK4	RPTOR	0	0	320	339	1	2
CDK4	NES	0	0	323	324	1	2
CDK4	MYCL	0	0	341	341	1	1
CDK4	CEBPD	0	0	162	187	1	1
CDK4	RAD17	0	0	182	261	1	1
CDK4	ZNF16	0	0	46	169	1	1
CDK4	MRPL11	0	0	0	182	1	1
CDK4	CDK2AP2	0	0	164	226	1	1
CDK4	FBXO7	0	0	119	200	1	1
CDK4	GNAS	0	0	321	404	1	1
CDK4	CNOT7	460	0	0	459	1	1
CDK4	POMC	0	0	163	163	1	1
CDK4	ANXA13	0	0	0	190	1	1
CDK4	NANOG	0	0	379	379	1	2
CDK4	CASP9	0	0	620	635	1	2
CDK4	ZNF219	128	0	0	184	1	1
CDK4	IMMT	0	0	67	152	1	1
CDK4	MAPK9	0	0	241	212	1	2
CDK4	OGG1	0	0	181	181	1	1
CDK4	PLK2	0	0	171	326	1	1
CDK4	PSKH2	0	0	0	244	1	1
CDK4	LIN52	0	0	234	287	1	1
CDK4	CHEK2	234	0	602	588	1	1
CDK4	FIP1L1	0	0	108	163	1	1
CDK4	SETD7	0	0	117	210	1	1
CDK4	SMARCA5	0	0	101	207	1	1
CDK4	POLR2D	0	0	134	191	1	1
CDK4	FASN	62	0	201	236	1	2
CDK4	ETS1	0	0	298	311	1	1
CDK4	ESCO2	0	0	0	312	1	1
CDK4	EIF4A3	0	0	81	310	1	1
CDK4	CCNDBP1	0	0	536	536	1	1
CDK4	SOS2	0	0	76	196	1	1
CDK4	ARL11	0	0	108	176	1	1
CDK4	PMS1	0	0	160	218	1	1
CDK4	RUVBL1	0	0	107	362	1	1
CDK4	ADIPOQ	0	0	148	171	1	2
CDK4	IGHV4-38-2	0	0	284	284	1	1
CDK4	VIM	0	0	210	238	1	2
CDK4	MAGEA3	0	0	184	183	1	2
CDK4	MOB1A	0	0	45	218	1	1
CDK4	FAM60A	0	0	67	160	1	1
CDK4	BCL11A	128	0	81	218	1	1
CDK4	PRKAB1	0	0	96	181	1	2
CDK4	SKP2	270	650	606	923	1	2
CDK4	GCLC	0	0	75	189	1	1
CDK4	BTG3	0	0	157	158	1	1
CDK4	MEIS2	0	0	72	152	1	1
CDK4	ANAPC1	0	0	127	390	1	1
CDK4	ARG1	0	0	180	189	1	2
CDK4	AURKB	0	0	503	529	1	1
CDK4	NISCH	0	0	57	157	1	1
CDK4	BCKDK	0	0	0	176	1	1
CDK4	TRIM16L	0	0	0	184	1	1
CDK4	FOXP1	0	0	181	298	1	1
CDK4	RAPGEF1	0	0	0	165	1	1
CDK4	ENO2	0	0	142	170	1	1
CDK4	E4F1	0	0	77	181	1	1
CDK4	TBX3	0	0	150	165	1	1
CDK4	BEST3	0	0	53	362	1	1
CDK4	PAK2	0	0	0	257	1	1
CDK4	TNS1	0	0	329	445	1	1
CDK4	KLF5	0	0	194	246	1	2
CDK4	PAK3	0	0	91	256	1	1
CDK4	TFF1	0	0	185	185	1	1
CDK4	PXN	0	0	213	243	1	1
CDK4	HIST2H3PS2	0	0	505	576	1	1
CDK4	HSPA6	0	0	60	174	1	1
CDK4	RPS5	0	0	74	182	1	1
CDK4	FOXI1	0	0	0	178	1	1
CDK4	CSK	0	0	114	230	1	1
CDK4	RPS6KB2	0	0	112	288	1	2
CDK4	HNRNPA2B1	0	0	108	156	1	1
CDK4	POLR2E	0	0	63	270	1	1
CDK4	HES5	0	0	158	157	1	1
CDK4	PPP1R10	0	0	108	158	1	1
CDK4	CTGF	0	0	283	282	1	1
CDK4	H2AFZ	0	900	113	926	1	1
CDK4	CCDC6	0	0	135	193	1	1
CDK4	DAPK3	0	0	75	230	1	2
CDK4	SMARCB1	0	650	393	834	1	1
CDK4	MX2	0	0	95	262	1	1
CDK4	FKBP1A	0	0	218	255	1	2
CDK4	NR3C1	0	0	323	335	1	1
CDK4	PDGFA	0	0	234	234	1	1
CDK4	CISH	0	0	173	173	1	1
CDK4	DLL3	0	0	155	154	1	1
CDK4	FKBP5	272	0	678	760	1	1
CDK4	GDPD4	0	0	0	207	1	1
CDK4	DPP4	0	0	90	171	1	1
CDK4	FANCM	0	0	99	270	1	1
CDK4	PFDN5	0	0	65	173	1	1
CDK4	PPP2R5A	0	0	95	223	1	1
CDK4	FOXI3	0	0	0	178	1	1
CDK4	LGALS4	0	0	361	361	1	1
CDK4	STK32A	0	0	0	258	1	1
CDK4	BOLA2B	0	0	0	166	1	1
CDK4	RHOB	0	0	160	258	1	1
CDK4	IL1A	0	0	181	181	1	1
CDK4	KIF20A	0	0	96	369	1	1
CDK4	CALML6	0	0	66	155	1	1
CDK4	H2AFX	0	600	392	783	1	1
CDK4	HIST1H2AB	0	0	60	157	1	1
CDK4	CUL5	0	0	134	228	1	1
CDK4	CCNB3	0	540	207	779	1	1
CDK4	SUZ12	0	0	323	323	1	1
CDK4	HIST1H4E	0	0	274	378	1	1
CDK4	YWHAG	0	0	95	157	1	1
CDK4	GLI2	0	0	204	333	1	2
CDK4	MAPKAPK2	0	0	124	272	1	1
CDK4	NEUROG3	0	0	195	195	1	1
CDK4	HDAC8	0	0	161	231	1	1
CDK4	CDK6	410	900	990	942	1	2
CDK4	KMT2B	0	0	234	284	1	1
CDK4	PLG	0	0	184	183	1	1
CDK4	GLIS2	129	0	42	186	1	1
CDK4	RPL6	0	0	68	152	1	1
CDK4	RERG	0	0	45	165	1	1
CDK4	FRK	0	0	69	204	1	1
CDK4	ZEB2	0	0	299	299	1	1
CDK4	RAP2B	0	0	90	197	1	1
CDK4	BCL2L10	0	0	134	162	1	1
CDK4	DDX55	0	0	0	289	1	1
CDK4	PTPRJ	0	0	97	254	1	1
CDK4	BMP7	0	0	170	169	1	1
CDK4	LIG3	0	0	74	201	1	1
CDK4	PIK3IP1	0	0	137	169	1	1
CDK4	NOTCH3	0	0	252	293	1	1
CDK4	HCFC1	0	0	122	154	1	1
CDK4	CSNK2A2	0	0	243	236	1	1
CDK4	ENSG00000272822	0	0	66	215	1	1
CDK4	HIST2H3D	0	0	0	180	1	1
CDK4	ARL17A	0	0	0	194	1	1
CDK4	CDK11B	0	0	293	217	1	1
CDK4	TICRR	0	0	71	199	1	1
CDK4	KIF4B	0	0	0	201	1	1
CDK4	PPEF1	0	0	0	172	1	1
CDK4	TNFRSF10A	0	0	292	304	1	1
CDK4	TUBB3	0	0	123	294	1	1
CDK4	KIF17	0	0	0	244	1	1
CDK4	HEPACAM2	0	0	0	191	1	1
CDK4	MCM4	0	0	343	578	1	1
CDK4	ALG1L2	0	0	0	180	1	1
CDK4	HESX1	0	0	0	160	1	1
CDK4	CLPTM1L	0	0	183	221	1	1
CDK4	CD276	0	0	134	159	1	1
CDK4	SDHA	0	0	161	179	1	1
CDK4	PPM1G	0	0	0	239	1	1
CDK4	CASP8	0	0	561	578	1	2
CDK4	KIF16B	0	0	0	213	1	1
CDK4	GADD45GIP1	0	0	101	196	1	1
CDK4	ITGB1	0	0	242	258	1	1
CDK4	PSMG2	0	0	96	150	1	1
CDK4	ENSG00000269905	0	0	165	302	1	1
CDK4	UBE2U	0	0	0	215	1	1
CDK4	BCL9	0	0	150	193	1	1
CDK4	KAT2A	270	0	218	448	1	1
CDK4	CDK19	0	0	292	233	1	1
CDK4	PGK1	0	0	123	216	1	2
CDK4	SGTA	0	0	57	150	1	1
CDK4	RALGPS1	0	0	0	165	1	1
CDK4	KIAA0101	0	0	66	160	1	1
CDK4	PIWIL4	0	0	165	171	1	1
CDK4	XRCC6	0	0	247	452	1	1
CDK4	NET1	0	0	47	197	1	1
CDK4	SIVA1	0	0	48	197	1	1
CDK4	GAS1	0	0	171	171	1	1
CDK4	MTAP	0	0	423	449	1	1
CDK4	TM4SF5	0	0	91	223	1	1
CDK4	NR2F1	0	0	153	167	1	1
CDK4	NF2	129	0	370	439	1	1
CDK4	ELAVL2	0	0	150	158	1	1
CDK4	GATA3	0	0	270	271	1	1
CDK4	NASP	0	0	0	256	1	1
CDK4	PYCR1	0	0	54	177	1	1
CDK4	TGFA	0	0	167	167	1	1
CDK4	CDK14	0	900	186	912	1	1
CDK4	AGO2	0	0	263	294	1	2
CDK4	PPP1R12C	0	0	49	158	1	1
CDK4	STAT3	0	0	676	723	1	2
CDK4	EZH2	0	0	556	599	1	2
CDK4	ADAM9	0	0	122	156	1	1
CDK4	UBE2T	0	0	81	257	1	1
CDK4	VDAC2	0	0	73	160	1	1
CDK4	LRRC49	0	0	0	185	1	1
CDK4	SETD8	0	0	150	228	1	1
CDK4	WNT5B	0	0	134	200	1	1
CDK4	POLR3B	0	0	0	171	1	1
CDK4	KARS	0	0	0	191	1	1
CDK4	DIRAS1	0	0	0	154	1	1
CDK4	PAK1	0	0	139	278	1	2
CDK4	KIF18B	0	0	53	252	1	1
CDK4	PSME3	0	0	108	191	1	1
CDK4	HSPB11	0	0	0	238	1	1
CDK4	CAMKK2	0	0	113	218	1	2
CDK4	KIF4A	0	0	73	284	1	1
CDK4	IMPACT	0	0	0	155	1	1
CDK4	PIN1	0	0	124	224	1	1
CDK4	FOXE3	0	0	0	178	1	1
CDK4	SRSF1	0	0	134	222	1	1
CDK4	OXSR1	0	0	0	183	1	1
CDK4	SNRPD1	0	0	48	167	1	2
CDK4	RALBP1	0	0	164	196	1	1
CDK4	ANKRD42	0	0	0	162	1	1
CDK4	CSF3	0	0	193	193	1	1
CDK4	PTPRD	0	0	280	348	1	1
CDK4	KIF15	0	0	124	306	1	1
CDK4	EXO1	0	0	128	412	1	1
CDK4	SLC2A2	0	0	228	244	1	1
CDK4	LMNA	0	0	276	307	1	2
CDK4	BRSK1	0	0	0	296	1	1
CDK4	MMRN1	0	0	0	164	1	1
CDK4	FGF7	0	0	143	179	1	1
CDK4	BOP1	0	0	122	273	1	1
CDK4	GNL3	0	0	128	180	1	1
CDK4	PPP1R27	0	0	0	151	1	1
CDK4	HK2	0	0	184	209	1	2
CDK4	DDIT3	0	0	450	466	1	2
CDK4	MED13	0	0	91	234	1	1
CDK4	RASGRP2	0	0	0	165	1	1
CDK4	PRKACG	0	0	0	267	1	1
CDK4	ARF5	0	0	66	160	1	1
CDK4	PRKX	0	0	0	251	1	1
CDK4	KLHL32	270	0	0	286	1	1
CDK4	MRPL13	0	0	0	163	1	1
CDK4	RHOXF2	0	0	0	160	1	1
CDK4	GART	0	0	45	173	1	1
CDK4	ERCC2	0	0	172	257	1	1
CDK4	TUBA4A	0	0	50	243	1	1
CDK4	DHH	0	0	95	192	1	1
CDK4	CKS1B	0	650	322	889	1	1
CDK4	TRIM24	0	0	170	188	1	1
CDK4	CFTR	0	0	142	173	1	2
CDK4	DDX54	0	0	0	201	1	1
CDK4	TTBK2	0	0	0	176	1	1
CDK4	KPNA4	0	0	0	210	1	1
CDK4	FOXS1	0	0	0	178	1	1
CDK4	RNASEH2A	0	0	63	267	1	1
CDK4	ESX1	0	0	0	160	1	1
CDK4	EME1	0	0	57	175	1	1
CDK4	FADD	0	0	324	342	1	2
CDK4	HIST1H4I	0	0	275	378	1	1
CDK4	METAP2	0	0	89	164	1	1
CDK4	PAK7	0	0	96	202	1	1
CDK4	EHMT2	0	0	172	341	1	2
CDK4	NFE2L2	0	0	266	266	1	2
CDK4	WDR62	0	0	0	158	1	1
CDK4	MAP2K5	179	0	74	368	1	1
CDK4	POLR2F	0	0	0	203	1	1
CDK4	GINS1	0	0	66	377	1	1
CDK4	FBXW8	0	0	141	269	1	1
CDK4	OGDHL	241	0	0	273	1	1
CDK4	AKT2	0	0	450	379	1	2
CDK4	PPP1R13B	0	0	143	196	1	1
CDK4	ENSG00000272772	0	0	0	283	1	1
CDK4	EML4	0	0	315	463	1	1
CDK4	UBE2K	0	0	184	273	1	1
CDK4	CDK20	0	0	268	391	1	1
CDK4	RPS19	0	0	70	270	1	1
CDK4	PSMA6	270	0	107	348	1	1
CDK4	CD80	0	0	170	169	1	2
CDK4	RSG1	0	0	0	154	1	1
CDK4	BRD9	0	0	81	168	1	1
CDK4	IKZF3	87	0	134	277	1	1
CDK4	ODC1	0	0	324	374	1	1
CDK4	MAP2K1	0	0	610	401	1	1
CDK4	HIST1H2BM	0	600	0	621	1	1
CDK4	CARD10	0	0	120	239	1	1
CDK4	EID1	0	0	329	329	1	1
CDK4	HIST1H4L	0	0	274	378	1	1
CDK4	HDAC3	0	0	92	176	1	2
CDK4	KIFC1	0	0	134	360	1	1
CDK4	PPP3CC	0	0	52	207	1	1
CDK4	MYCN	0	0	562	629	1	1
CDK4	SMAD4	0	900	586	957	1	2
CDK4	MEF2D	0	0	137	214	1	2
CDK4	SPAG5	0	0	89	184	1	1
CDK4	SEBOX	0	0	0	160	1	1
CDK4	MAU2	0	0	181	181	1	1
CDK4	HDAC5	0	0	108	203	1	1
CDK4	UBA1	0	0	122	190	1	1
CDK4	DMBT1	0	0	193	193	1	1
CDK4	HIST1H1A	756	0	0	812	1	1
CDK4	NUPR1	0	0	161	161	1	2
CDK4	FHL2	0	0	90	156	1	1
CDK4	METTL21B	0	0	181	181	1	1
CDK4	CEP97	0	0	0	185	1	1
CDK4	FHDC1	0	0	0	228	1	1
CDK4	ANAPC11	0	0	92	349	1	1
CDK4	LRFN3	0	0	67	153	1	1
CDK4	AGO4	0	650	0	664	1	1
CDK4	PARK7	0	0	91	154	1	2
CDK4	MYLK4	0	0	0	233	1	1
CDK4	BDP1	0	0	399	412	1	1
CDK4	GLS	0	0	150	176	1	2
CDK4	NOG	0	0	156	155	1	1
CDK4	GNAT3	0	0	0	210	1	1
CDK4	MEN1	0	0	413	425	1	1
CDK4	MX1	0	0	123	224	1	1
CDK4	STRN4	0	0	53	151	1	1
CDK4	TUBA3E	0	0	0	236	1	1
CDK4	KIF9	0	0	0	201	1	1
CDK4	PPP3CB	0	0	45	201	1	1
CDK4	NPC1	0	0	46	193	1	2
CDK4	MLH3	0	650	101	696	1	1
CDK4	RUVBL2	0	0	107	286	1	1
CDK4	TSFM	0	0	232	326	1	1
CDK4	TOP3A	0	800	49	818	1	1
CDK4	GNAT2	0	0	0	210	1	1
CDK4	PIK3CA	0	0	661	693	1	2
CDK4	APEX1	0	0	225	438	1	1
CDK4	PPIG	0	0	183	183	1	1
CDK4	WDR12	0	0	54	191	1	1
CDK4	STK32B	0	0	0	246	1	1
CDK4	GSC	0	0	0	160	1	1
CDK4	FABP7	0	0	306	306	1	1
CDK4	RARRES3	0	0	170	169	1	1
CDK4	PDK1	0	0	141	222	1	2
CDK4	MYC	679	0	752	927	1	2
CDK4	PAX7	0	0	264	280	1	1
CDK4	KIF18A	0	0	112	293	1	1
CDK4	DDX27	0	0	0	174	1	1
CDK4	PPIP5K1	0	0	0	254	1	1
CDK4	CDRT1	0	0	0	184	1	1
CDK4	DDX47	0	0	0	215	1	1
CDK4	HOXA9	0	0	218	218	1	1
CDK4	KIF2C	0	0	170	378	1	1
CDK4	USF1	0	0	113	160	1	1
CDK4	IGF1R	129	0	560	349	1	2
CDK4	SDHC	0	0	394	408	1	1
CDK4	SDHAF2	0	0	204	281	1	1
CDK4	FGF10	0	0	125	157	1	1
CDK4	RIT1	0	0	0	154	1	1
CDK4	HIST1H2BD	0	600	48	624	1	1
CDK4	H1F0	270	0	504	708	1	1
CDK4	HES6	0	0	95	158	1	1
CDK4	ENSG00000279576	0	0	202	202	1	1
CDK4	SNRPE	0	0	81	156	1	2
CDK4	PI3	0	0	170	169	1	2
CDK4	UBE2D1	0	0	96	187	1	1
CDK4	SMAD2	270	0	405	555	1	2
CDK4	KSR2	0	0	124	175	1	1
CDK4	CDK10	0	0	267	251	1	1
CDK4	TLR4	0	0	171	215	1	2
CDK4	GP9	0	0	0	170	1	1
CDK4	SLC20A1	0	0	0	165	1	1
CDK4	RIT2	0	0	0	154	1	1
CDK4	SVOPL	0	0	0	212	1	1
CDK4	PTPN9	0	0	112	226	1	1
CDK4	ATIC	0	0	48	269	1	2
CDK4	CHD7	0	0	73	180	1	1
CDK4	BRSK2	0	0	60	300	1	1
CDK4	POTEE	0	0	0	174	1	1
CDK4	GGCT	0	0	70	177	1	1
CDK4	ATRX	0	0	419	485	1	1
CDK4	SLC20A2	0	0	0	165	1	1
CDK4	JAG2	0	0	233	258	1	1
CDK4	RHOXF2B	0	0	0	160	1	1
CDK4	RAP1A	0	0	92	199	1	1
CDK4	NF1	0	0	604	639	1	1
CDK4	PAQR4	270	0	134	350	1	1
CDK4	HIST1H2AC	0	900	0	911	1	1
CDK4	KIF1A	0	0	0	201	1	1
CDK4	BCCIP	0	900	139	917	1	1
CDK4	OGFR	416	0	0	416	1	1
CDK4	MAPRE2	111	0	0	201	1	1
CDK4	KITLG	0	0	292	292	1	1
CDK4	SMARCAL1	0	0	0	151	1	1
CDK4	CALCR	0	0	73	170	1	1
CDK4	LONRF2	0	0	0	260	1	1
CDK4	FOXD4L5	0	0	0	178	1	1
CDK4	RAN	0	0	122	276	1	2
CDK4	PHLPP1	0	0	137	214	1	2
CDK4	LANCL2	0	0	113	186	1	1
CDK4	TRMT112	0	0	0	170	1	1
CDK4	WDR73	0	0	0	204	1	1
CDK4	UHRF1	0	0	133	207	1	1
CDK4	SOX12	0	0	44	161	1	1
CDK4	XPA	0	0	165	232	1	1
CDK4	DNMT3A	0	650	360	766	1	2
CDK4	DNMT3B	0	0	306	338	1	1
CDK4	RECQL	0	0	66	221	1	1
CDK4	BCL2L1	0	0	653	665	1	2
CDK4	ANAPC5	0	0	90	218	1	1
CDK4	TUBB4A	0	0	166	330	1	1
CDK4	PELP1	0	0	478	490	1	2
CDK4	WNT8A	0	0	112	206	1	1
CDK4	ANXA5	0	0	653	665	1	2
CDK4	CLPTM1	0	0	96	178	1	1
CDK4	PLAGL1	0	0	96	154	1	1
CDK4	CCNB1	0	900	825	992	1	1
CDK4	STARD9	0	0	0	201	1	1
CDK4	GALK1	0	0	0	231	1	1
CDK4	FOXM1	128	900	649	973	1	1
CDK4	WHSC1	0	0	157	197	1	1
CDK4	HES1	0	0	308	307	1	2
CDK4	RPS3	0	0	81	162	1	1
CDK4	MGMT	0	0	422	422	1	2
CDK4	PERP	0	0	182	188	1	1
CDK4	HSPD1	0	0	66	237	1	1
CDK4	EIF1B	0	0	45	209	1	1
CDK4	PPP2R2A	0	0	155	323	1	1
CDK4	RER1	0	0	0	209	1	1
CDK4	U2AF1L4	0	0	170	189	1	1
CDK4	KIF19	0	0	0	211	1	1
CDK4	PLK1	270	0	556	588	1	2
CDK4	RBM43	0	0	0	252	1	1
CDK4	EPO	0	0	180	179	1	2
CDK4	UBE2B	0	0	61	231	1	1
CDK4	TENC1	0	0	46	212	1	1
CDK4	MAPK4	0	0	88	192	1	1
CDK4	NOTCH4	0	0	193	193	1	1
CDK4	EP400	0	0	73	262	1	1
CDK4	DUSP15	0	0	0	193	1	1
CDK4	PRKACA	0	0	0	267	1	1
CDK4	CALB2	0	0	96	182	1	1
CDK4	KCNJ11	0	0	181	181	1	1
CDK4	IGFBP5	0	0	188	188	1	1
CDK4	POU3F2	0	0	155	211	1	1
CDK4	ARF1	0	0	46	297	1	1
CDK4	HSPA1L	0	0	0	216	1	1
CDK4	PSMA1	0	0	0	156	1	1
CDK4	BIRC2	0	0	323	348	1	1
CDK4	IFNG	0	0	218	252	1	2
CDK4	TUBB1	0	0	48	234	1	1
CDK4	NSF	0	0	0	171	1	2
CDK4	MTRNR2L6	0	0	204	204	1	1
CDK4	BAP1	0	0	257	275	1	1
CDK4	POLE	0	0	347	493	1	1
CDK4	TNFRSF17	0	0	90	164	1	1
CDK4	TGFB3	0	0	164	163	1	1
CDK4	CCL5	0	0	173	173	1	2
CDK4	STAG2	0	0	193	228	1	1
CDK4	TWSG1	0	0	183	183	1	1
CDK4	PPP1R12A	0	0	64	172	1	1
CDK4	RAB12	0	0	0	184	1	2
CDK4	MYSM1	0	0	0	175	1	1
CDK4	PALB2	0	0	404	404	1	1
CDK4	SERTAD1	486	0	966	981	1	1
CDK4	IL6	0	0	458	457	1	2
CDK4	RNASE1	0	0	213	213	1	1
CDK4	H3F3A	0	0	261	368	1	1
CDK4	BRD2	0	0	207	250	1	1
CDK4	CBX3	0	0	194	242	1	1
CDK4	RTF1	0	0	0	188	1	1
CDK4	FOXO6	0	0	112	239	1	1
CDK4	TNFRSF1A	0	0	249	248	1	1
CDK4	RPS6	0	0	310	363	1	2
CDK4	MYOG	0	0	383	392	1	1
CDK4	ACTN4	0	0	112	176	1	1
CDK4	CCNF	0	540	310	786	1	1
CDK4	ATRIP	0	0	151	150	1	1
CDK4	LSM4	0	0	0	176	1	1
CDK4	E2F6	0	0	688	744	1	1
CDK4	TBX2	0	0	166	180	1	1
CDK4	UBE2A	0	0	0	215	1	1
CDK4	SLC25A1	274	0	0	315	1	1
CDK4	TRAF4	0	0	112	177	1	1
CDK4	PIDD1	0	0	113	294	1	1
CDK4	CTAG1A	0	0	222	222	1	1
CDK4	FGF13	0	0	323	323	1	1
CDK4	PTPN13	0	0	67	167	1	1
CDK4	CCNC	0	0	458	648	1	1
CDK4	NOTCH1	0	0	561	585	1	2
CDK4	MAST1	0	0	0	296	1	1
CDK4	MSH5	0	600	57	649	1	1
CDK4	CD40LG	0	0	155	154	1	1
CDK4	PRMT1	0	0	204	381	1	1
CDK4	FKBP15	0	0	422	454	1	1
CDK4	RHOU	0	0	90	186	1	1
CDK4	RPL13A	0	0	95	161	1	1
CDK4	MYO9B	0	0	0	155	1	1
CDK4	DDX21	0	0	72	219	1	1
CDK4	KPNA1	0	0	45	213	1	1
CDK4	POTEF	0	0	286	385	1	1
CDK4	CALM1	0	0	108	286	1	1
CDK4	CHD6	0	0	46	157	1	1
CDK4	MAP1LC3A	0	0	135	203	1	2
CDK4	H2AFV	0	900	60	916	1	1
CDK4	CDK2	0	900	990	922	1	2
CDK4	SHMT2	0	0	125	392	1	1
CDK4	MCMDC2	0	0	150	349	1	1
CDK4	EPHA2	129	0	201	227	1	1
CDK4	UPK2	0	0	0	178	1	1
CDK4	EXOC8	0	0	0	276	1	1
CDK4	CDC73	0	0	150	210	1	1
CDK4	PSAT1	0	0	129	192	1	1
CDK4	CXCR2	0	0	166	165	1	1
CDK4	CSNK1G1	0	0	0	173	1	1
CDK4	DDX18	0	0	0	187	1	1
CDK4	FOXD4L4	0	0	70	203	1	1
CDK4	CDCA4	0	0	57	227	1	1
CDK4	PRKAG1	0	0	0	173	1	1
CDK4	XPO1	0	0	349	390	1	1
CDK4	CALD1	0	0	294	294	1	1
CDK4	HIF1A	178	0	517	599	1	2
CDK4	EDN1	0	0	192	192	1	1
CDK4	CYP27B1	0	0	212	231	1	1
CDK4	SMAD9	0	0	181	196	1	1
CDK4	GCK	0	0	181	181	1	1
CDK4	SIRT5	0	0	187	239	1	1
CDK4	DLG2	0	0	49	177	1	1
CDK4	SP1	270	0	507	649	1	2
CDK4	NKX6-2	0	0	150	195	1	1
CDK4	MAPKAPK5	0	0	0	168	1	1
CDK4	CCT5	0	0	0	238	1	1
CDK4	NAE1	0	0	74	172	1	1
CDK4	POLR1B	0	0	51	211	1	1
CDK4	RAD54L	0	0	148	362	1	1
CDK4	FAT1	0	0	251	275	1	1
CDK4	IL1B	0	0	294	310	1	2
CDK4	RPMS17	0	0	0	151	1	1
CDK4	CDCA5	0	0	88	209	1	1
CDK4	ID1	0	0	282	296	1	1
CDK4	LATS2	129	0	294	251	1	1
CDK4	UBE2R2	0	0	0	201	1	1
CDK4	MAPK13	0	0	143	266	1	1
CDK4	CRISP2	0	0	45	219	1	1
CDK4	CLN3	0	0	96	192	1	2
CDK4	PPP2R2D	0	0	45	235	1	1
CDK4	CNTD2	0	540	45	686	1	1
CDK4	PSMG1	0	0	0	172	1	1
CDK4	CDCA2	0	0	74	176	1	1
CDK4	MARCH9	0	0	166	179	1	1
CDK4	NUF2	0	0	96	275	1	1
CDK4	NCAPH	0	0	57	344	1	1
CDK4	HDAC9	0	0	166	220	1	1
CDK4	BRCA2	0	800	561	918	1	1
CDK4	REL	0	0	264	273	1	2
CDK4	EIF4B	0	0	155	202	1	1
CDK4	MLLT3	0	0	209	240	1	1
CDK4	KIF25	0	0	0	244	1	1
CDK4	TUBB6	0	0	57	268	1	1
CDK4	ERBB3	0	0	504	538	1	1
CDK4	RASGRP4	0	0	0	165	1	1
CDK4	CASP3	0	0	860	865	1	2
CDK4	SLC45A3	0	0	81	178	1	1
CDK4	PTGS2	0	0	392	392	1	2
CDK4	ZFAND3	0	0	0	189	1	1
CDK4	DDX6	0	0	67	281	1	1
CDK4	TGFBR3	0	0	133	195	1	1
CDK4	TUBB2B	0	0	0	230	1	1
CDK4	SLC25A16	0	0	151	158	1	1
CDK4	SMURF1	0	0	155	176	1	1
CDK4	UBA2	0	0	95	231	1	1
CDK4	IHH	0	0	170	259	1	1
CDK4	TNFSF13B	0	0	125	159	1	1
CDK4	POLR3A	0	0	0	230	1	1
CDK4	TNFRSF10B	0	0	391	401	1	2
CDK4	TONSL	0	0	0	174	1	1
CDK4	RASGRF1	0	0	44	168	1	1
CDK4	STK17B	0	0	0	241	1	1
CDK4	HP1BP3	0	0	0	252	1	1
CDK4	SEPT7	0	0	96	172	1	1
CDK4	CDC20B	0	0	0	403	1	1
CDK4	RAD21	0	0	161	270	1	1
CDK4	VEGFC	0	0	194	222	1	1
CDK4	HDAC11	0	0	149	203	1	1
CDK4	HARS	0	0	0	175	1	1
CDK4	DLG3	0	0	0	171	1	1
CDK4	HIST1H1E	0	0	0	253	1	1
CDK4	C17orf64	0	0	0	152	1	1
CDK4	MAPK15	0	0	150	241	1	1
CDK4	NME2	0	0	90	201	1	1
CDK4	INSM1	0	0	136	155	1	1
CDK4	SMARCA1	0	0	84	192	1	1
CDK4	RPS27A	0	0	96	155	1	1
CDK4	GUSB	272	0	114	343	1	1
CDK4	CDKN2A	913	900	989	999	1	2
CDK4	PPP6C	0	0	235	403	1	1
CDK4	GSK3B	0	900	392	923	1	2
CDK4	KRT7	0	0	188	188	1	1
CDK4	CDC34	0	0	212	343	1	1
CDK4	S100B	0	0	139	178	1	1
CDK4	MOK	0	0	151	189	1	1
CDK4	DDX42	0	0	0	174	1	1
CDK4	ORC4	0	0	95	154	1	1
CDK4	LHX6	0	0	0	160	1	1
CDK4	TUBG1	0	0	0	288	1	1
CDK4	CCNG1	0	540	320	782	1	1
CDK4	PLCZ1	0	0	53	225	1	1
CDK4	PFN1	0	0	0	174	1	1
CDK4	DUSP2	0	0	58	208	1	1
CDK4	ELSPBP1	0	0	459	468	1	1
CDK4	PTPRB	0	0	66	198	1	1
CDK4	BANF1	0	0	157	467	1	1
CDK4	ENSG00000258838	0	0	51	158	1	1
CDK4	KIDINS220	0	0	93	221	1	1
CDK4	PIK3CD	0	0	182	261	1	1
CDK4	INPP4B	0	0	164	163	1	1
CDK4	FGF9	0	0	137	169	1	1
CDK4	CEBPB	0	0	329	414	1	2
CDK4	ABCD4	0	0	262	278	1	1
CDK4	POC1A	0	0	0	204	1	1
CDK4	ERCC5	0	0	120	340	1	1
CDK4	WNT3	0	0	139	205	1	1
CDK4	PHC3	0	0	234	234	1	1
CDK4	CBX8	0	0	123	201	1	1
CDK4	TUBA8	0	0	0	236	1	1
CDK4	RIPK1	0	0	124	165	1	2
CDK4	PTGES3	0	0	261	384	1	1
CDK4	CCT7	0	0	0	386	1	1
CDK4	KDM6B	0	0	243	320	1	1
CDK4	FASLG	0	0	324	323	1	1
CDK4	SOCS3	0	0	173	191	1	1
CDK4	EIF3B	0	0	0	195	1	1
CDK4	DUSP27	0	0	0	193	1	1
CDK4	GAS7	0	0	0	162	1	1
CDK4	NUP155	128	0	57	199	1	1
CDK4	PRKAR1A	213	0	181	395	1	2
CDK4	WDR59	0	0	0	391	1	1
CDK4	ANKRD32	0	0	0	283	1	1
CDK4	RHOD	0	0	91	186	1	1
CDK4	NKPD1	0	0	0	162	1	1
CDK4	MCM6	0	0	341	551	1	1
CDK4	STAT5A	0	0	430	566	1	1
CDK4	PTPN18	0	0	0	168	1	1
CDK4	CLDN2	0	0	345	345	1	1
CDK4	RXRA	0	0	108	155	1	1
CDK4	BIRC7	0	0	182	213	1	1
CDK4	POC1B	0	0	0	219	1	1
CDK4	FOXN1	0	0	112	239	1	1
CDK4	FAF1	0	0	150	191	1	1
CDK4	SNRPB	0	0	0	266	1	1
CDK4	ANKRD53	0	0	0	208	1	1
CDK4	UPF1	0	0	54	154	1	1
CDK4	FOXK1	0	0	62	196	1	1
CDK4	ASCL1	0	0	193	193	1	1
CDK4	LIN54	0	0	181	370	1	1
CDK4	RAI14	0	0	0	164	1	1
CDK4	WDR17	0	0	0	248	1	1
CDK4	KDM2B	0	0	95	195	1	1
CDK4	HIST1H3E	0	0	194	311	1	1
CDK4	MLST8	0	0	150	157	1	1
CDK4	ANKEF1	0	0	0	208	1	1
CDK4	HNRNPC	0	0	134	203	1	1
CDK4	FANCG	0	0	155	205	1	1
CDK4	RPS14	0	0	107	169	1	1
CDK4	KRAS	0	0	613	842	1	2
CDK4	TSSK4	0	0	0	471	1	1
CDK4	RND2	0	0	64	162	1	1
CDK4	LRRC43	0	0	0	185	1	1
CDK4	FBXW10	0	0	0	184	1	1
CDK4	FOXD1	0	0	74	225	1	1
CDK4	ANAPC10	0	0	81	270	1	1
CDK4	BECN1	178	0	310	417	1	2
CDK4	MAPT	0	0	281	281	1	2
CDK4	EEF1G	0	0	56	277	1	1
CDK4	THBS1	0	0	260	260	1	1
CDK4	ABCB1	0	0	293	317	1	2
CDK4	FBXL19	0	0	0	171	1	1
CDK4	NUAK2	0	0	0	172	1	1
CDK4	SMARCD3	0	650	0	657	1	1
CDK4	SEPT14	0	0	113	180	1	1
CDK4	GYS1	0	0	55	270	1	1
CDK4	ASH2L	0	0	91	154	1	1
CDK4	IL2	0	0	358	359	1	1
CDK4	ABCC1	0	0	160	176	1	1
CDK4	MUC4	0	0	203	203	1	1
CDK4	HIST1H2BB	0	600	0	621	1	1
CDK4	MAPK11	0	0	107	261	1	1
CDK4	DUSP1	0	0	203	329	1	1
CDK4	SNRNP25	0	0	94	157	1	1
CDK4	NCAPD2	0	0	72	266	1	1
CDK4	SLC45A2	0	0	157	313	1	1
CDK4	PIAS1	204	0	67	252	1	1
CDK4	CDKN2C	882	900	979	999	1	1
CDK4	CAD	0	0	61	189	1	2
CDK4	HIST1H4G	0	0	0	178	1	1
CDK4	CHAF1A	0	0	74	172	1	1
CDK4	MLH1	0	650	455	823	1	1
CDK4	MSH4	0	600	67	642	1	1
CDK4	TUBG2	0	0	0	243	1	1
CDK4	FHAD1	0	0	47	197	1	1
CDK4	REM2	0	0	0	154	1	1
CDK4	PAK4	0	0	217	327	1	1
CDK4	CDC25A	0	900	681	984	1	1
CDK4	CAPN9	0	0	96	171	1	1
CDK4	PSMD2	0	0	73	348	1	1
CDK4	RBBP8	0	0	195	233	1	1
CDK4	CHD9	0	0	0	152	1	1
CDK4	CARD11	0	0	81	191	1	1
CDK4	FOXC1	0	0	115	242	1	1
CDK4	LPIN1	0	0	0	311	1	2
CDK4	BAGE5	0	0	235	235	1	1
CDK4	RHOXF1	0	0	0	160	1	1
CDK4	KDELR2	178	0	0	207	1	1
CDK4	YAP1	0	0	437	471	1	2
CDK4	OBFC1	0	0	82	318	1	1
CDK4	OTX2	128	0	81	164	1	1
CDK4	TNFAIP2	0	0	56	156	1	1
CDK4	MIB1	0	0	57	164	1	1
CDK4	IRF1	0	0	231	248	1	2
CDK4	GNB1L	0	0	0	248	1	1
CDK4	MYBL2	0	0	392	551	1	1
CDK4	TTF1	0	0	0	194	1	1
CDK4	HSF4	0	0	0	169	1	1
CDK4	FOXN2	0	0	0	178	1	1
CDK4	HIST2H3A	0	0	0	180	1	1
CDK4	CAMK1	270	0	96	426	1	1
CDK4	LGR5	0	0	213	253	1	1
CDK4	ENSG00000279765	0	0	0	152	1	1
CDK4	CTPS1	0	0	95	213	1	1
CDK4	SYP	0	0	167	191	1	1
CDK4	PPIL1	0	0	0	178	1	1
CDK4	POLD1	270	0	293	627	1	1
CDK4	PDK4	0	0	92	178	1	1
CDK4	H2AFY	0	0	107	181	1	1
CDK4	SENP3	128	0	52	193	1	1
CDK4	SMAD7	0	0	293	293	1	1
CDK4	PDCD1	0	0	284	284	1	2
CDK4	MAZ	0	0	43	159	1	1
CDK4	PIM2	0	0	203	307	1	1
CDK4	ESR1	0	0	681	686	1	2
CDK4	MSH2	0	0	424	489	1	1
CDK4	IFNB1	0	0	175	181	1	1
CDK4	NCL	0	0	218	286	1	2
CDK4	NSD1	0	0	112	154	1	1
CDK4	UBE2D2	0	0	60	155	1	1
CDK4	PPA1	0	0	82	211	1	1
CDK4	KIF3A	0	0	46	205	1	1
CDK4	LMNB1	0	0	292	347	1	1
CDK4	PRL	0	0	218	277	1	1
CDK4	EOMES	0	0	142	244	1	1
CDK4	IFT80	0	0	0	248	1	1
CDK4	NUAK1	0	0	211	219	1	1
CDK4	RARS	0	0	108	181	1	1
CDK4	FBXO31	0	0	45	212	1	1
CDK4	RAD51B	0	0	175	317	1	1
CDK4	TBP	0	0	219	262	1	1
CDK4	FN1	0	0	399	412	1	2
CDK4	GALNT13	0	0	0	212	1	1
CDK4	RASL11B	0	0	0	154	1	1
CDK4	CSNK2B	0	0	74	185	1	1
CDK4	ESRP1	0	0	81	162	1	1
CDK4	NONO	0	0	107	161	1	1
CDK4	GEM	0	0	0	154	1	1
CDK4	MMP13	0	0	143	175	1	2
CDK4	EML3	0	0	0	248	1	1
CDK4	RPL5	0	0	101	159	1	1
CDK4	PRKCA	0	0	322	151	1	1
CDK4	MAPKAPK3	0	0	76	268	1	1
CDK4	CCNL2	0	0	141	349	1	1
CDK4	PLK3	0	0	163	309	1	1
CDK4	CAMK2A	0	0	75	171	1	2
CDK4	SSX1	0	0	178	177	1	1
CDK4	RAD52	0	0	124	276	1	1
CDK4	RIPK4	0	0	48	197	1	1
CDK4	HINT1	0	0	52	187	1	1
CDK4	SETD2	0	0	270	338	1	1
CDK4	CDC25B	0	0	469	731	1	1
CDK4	MAP1LC3B	0	0	323	350	1	2
CDK4	TIMP2	0	0	248	248	1	1
CDK4	PIGA	0	0	0	191	1	1
CDK4	SPHK2	0	0	135	163	1	1
CDK4	SASS6	0	0	278	307	1	1
CDK4	TEAD4	0	0	108	204	1	1
CDK4	SERPINB5	0	0	193	193	1	1
CDK4	PSMC3IP	0	900	0	904	1	1
CDK4	SPHK1	0	0	184	205	1	2
CDK4	TTK	0	0	243	335	1	1
CDK4	SNX13	0	0	44	214	1	1
CDK4	CDC45	673	0	285	843	1	1
CDK4	NKX2-1	0	0	247	259	1	1
CDK4	ESPN	0	0	63	163	1	1
CDK4	TERT	129	0	634	704	1	2
CDK4	YBX3	270	800	913	986	1	1
CDK4	GDE1	0	0	0	207	1	1
CDK4	MCM2	684	0	420	889	1	1
CDK4	TET2	0	0	209	209	1	2
CDK4	TFDP3	0	0	98	263	1	1
CDK4	TYRP1	0	0	294	294	1	1
CDK4	VAV1	0	0	134	164	1	1
CDK4	PSKH1	0	0	0	235	1	1
CDK4	INCA1	75	0	134	164	1	1
CDK4	IL10	0	0	253	252	1	2
CDK4	SNAI1	0	0	464	464	1	1
CDK4	PPP3R1	0	0	124	162	1	1
CDK4	UBE2S	0	0	203	364	1	1
CDK4	FGFR4	129	0	321	226	1	1
CDK4	ASPM	192	0	125	402	1	1
CDK4	MRAS	0	0	72	181	1	1
CDK4	PA2G4	0	0	73	282	1	1
CDK4	IRAK4	0	0	52	241	1	1
CDK4	DAPK2	0	0	49	224	1	2
CDK4	NPM1	0	0	401	463	1	1
CDK4	TAF1L	0	0	134	190	1	1
CDK4	FLT3	0	0	417	188	1	2
CDK4	PTPRF	0	0	72	159	1	1
CDK4	SMARCC2	0	650	102	685	1	1
CDK4	FOXD4L6	0	0	0	178	1	1
CDK4	MARCKS	270	0	92	308	1	1
CDK4	FAM57A	0	0	150	181	1	1
CDK4	CCNL1	0	0	0	273	1	1
CDK4	DLG4	0	0	66	188	1	2
CDK4	CNPY2	0	0	0	179	1	1
CDK4	GDF15	0	0	181	187	1	1
CDK4	SOX10	0	0	242	241	1	1
CDK4	UBE2O	0	0	0	150	1	1
CDK4	DIRAS2	0	0	0	154	1	1
CDK4	OGT	0	0	96	195	1	2
CDK4	ANKDD1A	0	0	0	208	1	1
CDK4	MDM4	180	0	560	626	1	1
CDK4	GOT2	0	0	112	198	1	1
CDK4	ENG	0	0	170	169	1	2
CDK4	HMP19	0	0	327	341	1	1
CDK4	IGF2	0	0	372	372	1	1
CDK4	TEAD1	0	0	150	203	1	1
CDK4	PTPN20A	0	0	0	168	1	1
CDK4	UNG	0	0	108	226	1	1
CDK4	CASKIN2	0	0	0	166	1	1
CDK4	REV3L	0	0	0	210	1	1
CDK4	RFWD3	0	0	64	192	1	1
CDK4	CNTN2	270	0	57	282	1	1
CDK4	TNFRSF9	0	0	157	156	1	1
CDK4	PSMC3	0	0	57	215	1	1
CDK4	KAT5	0	0	168	191	1	1
CDK4	TSSK6	0	0	0	248	1	1
CDK4	HIST1H4K	0	0	275	378	1	1
CDK4	NGFR	0	0	171	171	1	1
CDK4	E2F3	0	900	839	987	1	1
CDK4	BUB3	0	0	269	580	1	1
CDK4	CDX2	0	0	170	213	1	1
CDK4	PRIM1	0	0	206	415	1	1
CDK4	H2BFS	0	600	0	621	1	1
CDK4	HIST1H3B	0	0	186	304	1	1
CDK4	CHURC1-FNTB	0	0	61	175	1	1
CDK4	RARB	0	0	183	196	1	1
CDK4	CHD2	0	0	0	152	1	1
CDK4	LDHA	0	0	299	336	1	2
CDK4	RPL34	270	0	81	315	1	1
CDK4	KIT	0	0	565	253	1	2
CDK4	COMMD3-BMI1	0	0	517	548	1	1
CDK4	CCNA1	0	900	558	969	1	1
CDK4	NTRK3	0	0	208	151	1	1
CDK4	DUSP28	0	0	0	182	1	1
CDK4	NUDT1	0	0	113	197	1	1
CDK4	GAPDHS	0	0	0	225	1	1
CDK4	BHLHE41	0	0	162	161	1	1
CDK4	PDCD1LG2	0	0	213	213	1	1
CDK4	RECQL5	0	0	0	200	1	1
CDK4	NFATC1	0	0	309	309	1	2
CDK4	E2F5	0	900	710	980	1	1
CDK4	AGO1	0	650	122	693	1	1
CDK4	TERF1	0	0	194	211	1	1
CDK4	NUTF2	0	0	66	153	1	1
CDK4	PCDHA9	0	0	122	156	1	1
CDK4	PTTG1	0	0	321	436	1	1
CDK4	FOXL1	0	0	49	185	1	1
CDK4	BMPR1A	0	0	321	199	1	1
CDK4	NEK6	0	0	127	250	1	1
CDK4	HELZ2	0	0	0	157	1	1
CDK4	DUSP6	0	0	184	304	1	1
CDK4	GSTT2B	0	0	0	173	1	1
CDK4	PDPK1	0	0	233	262	1	2
CDK4	AVIL	0	0	180	207	1	1
CDK4	DDX5	0	0	122	233	1	1
CDK4	CAT	0	0	294	294	1	2
CDK4	GFI1	0	0	108	165	1	1
CDK4	WNT10B	0	0	172	171	1	1
CDK4	BARD1	0	0	390	479	1	1
CDK4	DEK	0	0	164	202	1	1
CDK4	MDM1	0	0	321	321	1	1
CDK4	HGF	178	0	392	491	1	2
CDK4	KIF14	0	0	81	266	1	1
CDK4	NUMBL	0	0	90	157	1	1
CDK4	POU5F1	0	0	469	513	1	2
CDK4	MCM7	0	0	598	750	1	1
CDK4	PCED1B	0	0	0	158	1	1
CDK4	HRK	0	0	157	156	1	1
CDK4	RASA1	0	0	150	181	1	1
CDK4	MECOM	0	0	166	220	1	1
CDK4	CANX	0	0	141	162	1	2
CDK4	HIST1H3F	0	0	183	301	1	1
CDK4	CCT6A	0	0	0	209	1	1
CDK4	MLANA	0	0	376	376	1	1
CDK4	RAD54B	0	0	66	283	1	1
CDK4	BAK1	0	0	218	275	1	2
CDK4	PTPN2	0	0	87	208	1	2
CDK4	RPA1	270	600	161	796	1	1
CDK4	MYB	0	0	292	416	1	1
CDK4	BCL2	217	0	218	397	1	2
CDK4	KIF22	0	0	48	264	1	1
CDK4	PITPNA	0	0	0	210	1	1
CDK4	SMAD6	0	0	158	157	1	1
CDK4	FOXA2	0	0	154	278	1	1
CDK4	EEF1E1	0	0	46	196	1	1
CDK4	ITSN1	0	0	0	199	1	1
CDK4	DDIT4	0	0	150	182	1	2
CDK4	AARS	0	0	0	311	1	1
CDK4	DDX46	0	0	0	174	1	1
CDK4	SSH3	0	0	0	193	1	1
CDK4	RNASEL	0	0	0	225	1	1
CDK4	HPRT1	0	0	167	185	1	1
CDK4	HOXB13	0	0	143	174	1	1
CDK4	FBXL18	0	0	0	189	1	1
CDK4	CTLA4	0	0	391	390	1	2
CDK4	MTRF1L	0	0	0	161	1	1
CDK4	RRAS2	0	0	91	259	1	1
CDK4	MAD2L2	0	0	108	152	1	1
CDK4	KIF12	0	0	0	201	1	1
CDK4	TP53I3	0	0	182	200	1	1
CDK4	BLM	0	800	56	845	1	2
CDK4	LIN28A	0	0	260	266	1	1
CDK4	HDAC7	0	0	95	154	1	1
CDK4	RCC1	0	0	588	631	1	1
CDK4	UNCX	0	0	0	160	1	1
CDK4	DUSP18	0	0	0	182	1	1
CDK4	ULK3	0	0	66	217	1	2
CDK4	ANKDD1B	0	0	0	208	1	1
CDK4	DDB2	0	0	181	181	1	1
CDK4	CD274	0	0	469	469	1	2
CDK4	SREBF2	0	0	57	202	1	1
CDK4	HSF2	0	0	0	169	1	1
CDK4	BCL2L2	0	0	324	334	1	1
CDK4	ATR	0	0	289	506	1	2
CDK4	FAM58A	0	0	73	275	1	1
CDK4	TMEM97	0	0	122	176	1	1
CDK4	FOXC2	0	0	117	243	1	1
CDK4	ABCG2	0	0	310	320	1	1
CDK4	ABCB5	0	0	306	317	1	1
CDK4	PDLIM7	0	0	113	165	1	1
CDK4	RERGL	0	0	0	154	1	1
CDK4	RALGPS2	0	0	0	165	1	1
CDK4	IRS1	0	0	286	305	1	2
CDK4	SGK1	0	0	181	296	1	2
CDK4	HSPA9	0	0	134	264	1	1
CDK4	LOX	0	0	251	268	1	2
CDK4	EGR2	0	0	139	194	1	1
CDK4	SMTN	151	0	57	201	1	1
CDK4	FOXD4	0	0	0	178	1	1
CDK4	NTRK1	63	0	391	233	1	1
CDK4	PGR	0	0	468	476	1	1
CDK4	HIST1H4B	0	0	274	378	1	1
CDK4	MUC1	0	0	243	261	1	1
CDK4	NCOR1	0	0	214	250	1	1
CDK4	CDK1	0	900	816	933	1	2
CDK4	DOT1L	0	0	140	201	1	1
CDK4	LEPREL2	0	0	180	179	1	1
CDK4	SERPINE1	0	0	250	250	1	1
CDK4	AHR	0	0	267	326	1	2
CDK4	ZBTB32	0	0	0	159	1	1
CDK4	CRBN	0	0	184	360	1	1
CDK4	TTBK1	0	0	0	227	1	1
CDK4	RPS6KB1	0	0	556	402	1	2
CDK4	REM1	0	0	0	517	1	1
CDK4	LMO4	0	0	0	160	1	1
CDK4	FCGR1A	0	0	167	167	1	1
CDK4	RHEBL1	0	0	0	154	1	1
CDK4	EZH1	0	0	113	158	1	1
CDK4	ANKRD60	0	0	0	208	1	1
CDK4	ARNTL	0	0	150	163	1	1
CDK4	EPB41L1	0	0	330	330	1	1
CDK4	TAF5	0	0	0	248	1	1
CDK4	FHIT	0	0	294	340	1	1
CDK4	ESCO1	0	0	0	312	1	1
CDK4	FOXL2	0	0	156	277	1	1
CDK4	PPP2R2B	0	0	62	249	1	1
CDK4	DDX53	0	0	199	307	1	1
CDK4	HIST1H2AJ	0	900	0	908	1	1
CDK4	CDH5	0	0	138	217	1	1
CDK4	CASK	0	0	53	167	1	1
CDK4	ATF3	0	0	228	227	1	2
CDK4	FBXW2	0	0	0	204	1	1
CDK4	ENSG00000142539	0	0	0	284	1	1
CDK4	ANKRD27	0	0	0	157	1	1
CDK4	PCGF2	0	0	113	164	1	1
CDK4	KIF26B	0	0	0	201	1	1
CDK4	DP2	0	0	165	302	1	1
CDK4	RPA4	0	0	0	287	1	1
CDK4	CSNK2A1	0	0	222	223	1	1
CDK4	SUPT5H	0	0	64	174	1	1
CDK4	PTGES3L	0	0	0	192	1	1
CDK4	TXNIP	0	0	171	192	1	2
CDK4	SRSF2	0	0	125	181	1	1
CDK4	BMF	0	0	167	167	1	1
CDK4	SMC5	0	0	55	280	1	1
CDK4	OXA1L	0	0	0	158	1	1
CDK4	SSU72	0	0	0	251	1	1
CDK4	NFKB2	0	0	212	296	1	1
CDK4	GSTP1	0	0	228	238	1	1
CDK4	RND3	0	0	122	214	1	1
CDK4	TCP1	0	0	77	191	1	1
CDK4	ARX	0	0	0	160	1	1
CDK4	TMPRSS2	0	0	241	240	1	1
CDK4	PIK3C2G	0	0	95	182	1	1
CDK4	MRTO4	0	0	0	173	1	1
CDK4	GCG	0	0	218	218	1	1
CDK4	CDC7	686	0	391	877	1	1
CDK4	TNFAIP3	0	0	166	165	1	2
CDK4	PPP1R14B	0	0	0	171	1	1
CDK4	MAP3K14	0	0	82	151	1	1
CDK4	TFAP2A	0	0	141	159	1	1
CDK4	MND1	0	900	0	907	1	1
CDK4	CDK13	462	720	242	873	1	1
CDK4	TFRC	0	0	166	202	1	1
CDK4	CCND2	897	900	989	999	1	1
CDK4	PDGFC	0	0	95	160	1	1
CDK4	RBBP7	0	0	124	312	1	1
CDK4	TPX2	0	0	211	355	1	1
CDK4	PAX3	0	0	317	332	1	1
CDK4	PGM5	0	0	0	179	1	1
CDK4	PLAG1	0	0	143	207	1	1
CDK4	FNIP2	270	0	0	270	1	1
CDK4	EEF2	0	0	195	215	1	2
CDK4	CDK3	0	0	620	185	1	1
CDK4	SLC7A11	0	0	271	296	1	2
CDK4	STIP1	0	0	174	299	1	1
CDK4	PEBP1	0	0	164	210	1	1
CDK4	ERCC3	0	0	171	228	1	1
CDK4	IFI27	213	0	0	213	1	1
CDK4	RCAN1	0	0	306	322	1	2
CDK4	NAIP	0	0	128	161	1	1
CDK4	DDX17	0	0	90	205	1	1
CDK4	PGM1	0	0	0	179	1	1
CDK4	LPIN2	0	0	0	311	1	1
CDK4	DLGAP2	0	0	0	192	1	1
CDK4	TRAP1	177	0	63	429	1	2
CDK4	VDR	0	0	244	256	1	2
CDK4	FBXO18	0	0	0	279	1	1
CDK4	PIK3R2	0	0	150	176	1	1
CDK4	ANKLE1	0	0	49	215	1	1
CDK4	MMP3	0	0	210	215	1	1
CDK4	GFER	207	0	0	224	1	1
CDK4	KRT14	0	0	243	242	1	1
CDK4	MEF2C	0	0	156	230	1	1
CDK4	ANKRD1	0	0	62	181	1	1
CDK4	SIN3A	0	0	123	241	1	1
CDK4	CNPPD1	0	540	0	783	1	1
CDK4	PTMA	270	0	115	369	1	1
CDK4	LAPTM4A	0	0	0	188	1	1
CDK4	C22orf29	0	0	212	212	1	1
CDK4	TNF	0	0	423	443	1	2
CDK4	MSX1	0	0	124	156	1	1
CDK4	BCAS2	0	0	161	180	1	1
CDK4	DNAJC6	0	0	0	206	1	1
CDK4	PRC1	0	0	61	405	1	1
CDK4	STK32C	0	0	0	246	1	1
CDK4	XIAP	0	0	517	541	1	2
CDK4	KIF26A	0	0	0	201	1	1
CDK4	PPP2R4	0	0	323	348	1	1
CDK4	HIST2H2AB	0	0	0	153	1	1
CDK4	DLG1	0	0	72	197	1	1
CDK4	RUNX2	0	900	321	931	1	2
CDK4	PSPH	0	0	120	195	1	1
CDK4	KATNA1	0	0	0	190	1	1
CDK4	SLC25A3	0	0	60	183	1	1
CDK4	PHKG2	0	0	0	194	1	1
CDK4	ATF6	0	0	181	181	1	2
CDK4	IKBKB	0	0	324	183	1	2
CDK4	GSTM1	0	0	144	177	1	1
CDK4	HAS3	0	0	0	217	1	1
CDK4	KLF4	0	0	324	367	1	2
CDK4	SPATA5	0	0	0	223	1	1
CDK4	FGFR1	0	0	520	216	1	1
CDK4	WDR78	0	0	0	248	1	1
CDK4	HUS1	0	0	164	233	1	1
CDK4	HIST1H2BA	0	600	0	621	1	1
CDK4	RRM1	0	0	181	440	1	1
CDK4	CD4	0	0	341	341	1	2
CDK4	ATF4	0	0	162	180	1	2
CDK4	CCNYL1	0	0	0	266	1	1
CDK4	USO1	0	0	0	154	1	1
CDK4	GNAL	0	0	0	159	1	1
CDK4	HOXA10	0	0	195	195	1	1
CDK4	SGK3	0	0	144	291	1	1
CDK4	TUBA3C	0	0	0	236	1	1
CDK4	PRDM16	0	0	97	155	1	1
CDK4	CARD14	0	0	0	156	1	1
CDK4	SYNJ2	0	0	0	205	1	1
CDK4	PTHLH	0	0	176	177	1	1
CDK4	KNTC1	0	0	123	211	1	1
CDK4	FOXA1	0	0	287	392	1	1
CDK4	DUSP23	0	0	0	182	1	1
CDK4	TEAD2	129	0	70	228	1	1
CDK4	LHX2	0	0	96	229	1	1
CDK4	MKI67	0	0	326	600	1	2
CDK4	AKT1	138	0	879	548	1	2
CDK4	PTP4A3	0	0	120	176	1	1
CDK4	TGFB2	0	0	294	294	1	1
CDK4	CAPN1	0	0	107	191	1	2
CDK4	PPP1R13L	0	0	204	204	1	1
CDK4	PPARG	0	0	414	423	1	2
CDK4	UBE3A	270	0	141	371	1	1
CDK4	BBC3	0	0	248	248	1	2
CDK4	FOXD4L3	0	0	0	178	1	1
CDK4	FANCD2	0	0	222	262	1	1
CDK4	FOXF2	0	0	55	190	1	1
CDK4	GYS2	0	0	0	259	1	1
CDK4	ERBB2	273	0	737	503	1	2
CDK4	HMGA2	0	0	556	573	1	1
CDK4	HIST1H3G	0	0	183	301	1	1
CDK4	UBXN10	270	0	0	270	1	1
CDK4	ILF2	0	0	45	247	1	1
CDK4	CDK15	0	0	181	178	1	1
CDK4	ATP6V1A	0	0	0	210	1	1
CDK4	ANAPC4	0	0	108	182	1	1
CDK4	TOP1MT	0	0	0	166	1	1
CDK4	IGF2R	0	0	134	164	1	1
CDK4	CCNE2	0	900	731	985	1	1
CDK4	ENSA	0	0	48	221	1	1
CDK4	MAP3K1	0	0	323	202	1	1
CDK4	AHSA1	0	0	395	448	1	1
CDK4	RHOC	0	0	213	327	1	1
CDK4	RNF7	0	0	70	167	1	1
CDK4	WDHD1	0	0	73	283	1	1
CDK4	SMC4	0	0	46	455	1	1
CDK4	FGF3	0	0	260	260	1	1
CDK4	ANK3	0	0	0	208	1	1
CDK4	ING5	0	0	167	212	1	1
CDK4	OIP5	0	0	107	184	1	1
CDK4	MCM9	0	0	126	368	1	1
CDK4	CSMD3	0	0	95	162	1	1
CDK4	SIRT4	0	0	181	216	1	1
CDK4	USP3	0	0	57	174	1	1
CDK4	CEP57	0	0	0	199	1	1
CDK4	BIRC5	270	0	450	626	1	2
CDK4	ID2	0	0	184	185	1	1
CDK4	WWOX	0	0	164	170	1	1
CDK4	EMD	0	0	155	213	1	1
CDK4	CCNG2	0	540	369	798	1	1
CDK4	IL11	0	0	150	203	1	1
CDK4	FOXE1	0	0	58	193	1	1
CDK4	CDC16	0	0	261	519	1	1
CDK4	STAT6	0	0	265	351	1	1
CDK4	UBE2C	0	0	211	410	1	1
CDK4	TUBB8B	0	0	0	230	1	1
CDK4	EIF2AK3	0	0	466	239	1	2
CDK4	FOXJ2	0	0	0	178	1	1
CDK4	STK25	0	0	46	179	1	1
CDK4	TEN1-CDK3	0	0	619	185	1	1
CDK4	TASP1	0	0	75	216	1	1
CDK4	PSMB5	0	0	125	246	1	1
CDK4	VHL	128	0	123	203	1	2
CDK4	CADM1	0	0	212	212	1	1
CDK4	IQGAP3	0	0	74	191	1	1
CDK4	TUBB8	0	0	0	230	1	1
CDK4	RABGEF1	0	0	0	174	1	1
CDK4	ARPP19	0	0	0	215	1	1
CDK4	CIB1	111	0	638	679	1	1
CDK4	FRMPD2	0	0	0	175	1	1
CDK4	SERTAD4	0	0	0	177	1	1
CDK4	SMURF2	0	0	135	156	1	1
CDK4	CCNI2	0	540	82	698	1	1
CDK4	KATNAL1	0	0	0	190	1	1
CDK4	TUBA1C	0	0	63	330	1	1
CDK4	MCM3	0	0	390	711	1	1
CDK4	SMARCC1	0	650	111	700	1	1
CDK4	HSPA12A	0	0	0	158	1	1
CDK4	XRCC2	0	0	166	165	1	1
CDK4	SRC	0	900	593	935	1	2
CDK4	DLGAP4	0	0	0	192	1	1
CDK4	EED	0	0	154	244	1	1
CDK4	RASGEF1B	0	0	0	165	1	1
CDK4	RCC2	0	0	77	237	1	1
CDK4	ACTL6A	0	650	84	726	1	1
CDK4	KIF5B	0	0	150	309	1	1
CDK4	CDC37L1	0	0	92	273	1	1
CDK4	YWHAB	0	0	143	202	1	1
CDK4	PCSK9	0	0	242	270	1	1
CDK4	C17orf49	0	0	102	164	1	1
CDK4	DUSP19	0	0	0	193	1	1
CDK4	KDM6A	0	0	246	323	1	1
CDK4	MEF2B	0	0	96	175	1	1
CDK4	GTF2B	0	0	123	177	1	1
CDK4	CTCF	0	0	183	236	1	1
CDK4	STK3	0	0	0	244	1	1
CDK4	CDCA8	0	0	297	401	1	1
CDK4	DUSP13	0	0	0	193	1	1
CDK4	GPC3	0	0	133	215	1	1
CDK4	CDKN1B	981	800	989	999	1	2
CDK4	KIF24	0	0	0	219	1	1
CDK4	RB1	992	900	919	999	1	2
CDK4	FKBPL	0	0	108	323	1	1
CDK4	HEXIM1	270	0	202	392	1	1
CDK4	IFIT1	0	0	68	163	1	1
CDK4	DUXA	0	0	0	160	1	1
CDK4	CAMK1G	0	0	0	230	1	1
CDK4	TRRAP	0	0	194	307	1	1
CDK4	HACE1	0	0	0	214	1	1
CDK4	RBX1	0	0	181	282	1	1
CDK4	PPM1D	0	0	328	371	1	1
CDK4	TSC2	270	0	560	749	1	2
CDK4	POLR2B	0	0	0	172	1	1
CDK4	PTPDC1	0	0	0	182	1	1
CDK4	IFT88	0	0	0	202	1	1
CDK4	OTP	0	0	0	160	1	1
CDK4	PTPRQ	0	0	0	177	1	1
CDK4	EIF2S1	0	0	184	208	1	2
CDK4	NWD1	0	0	0	256	1	1
CDK4	LDHB	0	0	116	189	1	1
CDK4	RASSF1	142	0	369	501	1	1
CDK4	MITF	0	0	529	529	1	2
CDK4	MOS	0	0	0	236	1	1
CDK4	JAK1	0	0	423	270	1	2
CDK4	PTPN7	0	0	0	168	1	1
CDK4	HAS2	0	0	81	467	1	1
CDK4	NFATC2	0	0	323	323	1	1
CDK4	TCHP	0	0	948	948	1	1
CDK4	MCTS1	0	0	44	163	1	1
CDK4	LRRK1	0	0	0	166	1	1
CDK4	GPCPD1	0	0	0	365	1	1
CDK4	RHOH	0	0	64	162	1	1
CDK4	LIN28B	0	0	195	414	1	1
CDK4	NRG1	0	0	163	169	1	2
CDK4	POLD3	0	0	134	184	1	1
CDK4	FBXL6	270	0	450	624	1	1
CDK4	HMOX1	0	0	299	315	1	2
CDK4	ING4	0	0	143	189	1	1
CDK4	KDM5A	0	0	204	210	1	1

Ontologies

ID	Category	Term	Effect	Evidence
GO:0005524	Molecular Function	ATP binding	enables	IEA
GO:0030332	Molecular Function	cyclin binding	enables	IBA
GO:0030332	Molecular Function	cyclin binding	enables	IPI
GO:0004693	Molecular Function	cyclin-dependent protein serine/threonine kinase activity	enables	IBA
GO:0004693	Molecular Function	cyclin-dependent protein serine/threonine kinase activity	enables	IDA
GO:0004693	Molecular Function	cyclin-dependent protein serine/threonine kinase activity	enables	TAS
GO:0016538	Molecular Function	cyclin-dependent protein serine/threonine kinase regulator activity	enables	TAS
GO:0005515	Molecular Function	protein binding	enables	IPI
GO:0106310	Molecular Function	protein serine kinase activity	enables	IEA
GO:0000082	Biological Process	G1/S transition of mitotic cell cycle	involved_in	IBA
GO:0000082	Biological Process	G1/S transition of mitotic cell cycle	involved_in	IDA
GO:0000082	Biological Process	G1/S transition of mitotic cell cycle	involved_in	IMP
GO:0000082	Biological Process	G1/S transition of mitotic cell cycle	involved_in	NAS
GO:0051301	Biological Process	cell division	involved_in	IEA
GO:0071353	Biological Process	cellular response to interleukin-4	involved_in	IEA
GO:1904637	Biological Process	cellular response to ionomycin	involved_in	IEA
GO:0071222	Biological Process	cellular response to lipopolysaccharide	involved_in	IEA
GO:1904628	Biological Process	cellular response to phorbol 13-acetate 12-myristate	involved_in	IEA
GO:0010971	Biological Process	positive regulation of G2/M transition of mitotic cell cycle	involved_in	IDA
GO:0008284	Biological Process	positive regulation of cell population proliferation	involved_in	IMP
GO:0048146	Biological Process	positive regulation of fibroblast proliferation	involved_in	IMP
GO:0006468	Biological Process	protein phosphorylation	involved_in	IBA
GO:0006468	Biological Process	protein phosphorylation	involved_in	IDA
GO:0010389	Biological Process	regulation of G2/M transition of mitotic cell cycle	involved_in	IBA
GO:0051726	Biological Process	regulation of cell cycle	involved_in	IDA
GO:0010468	Biological Process	regulation of gene expression	involved_in	IBA
GO:0010468	Biological Process	regulation of gene expression	involved_in	IMP
GO:0060260	Biological Process	regulation of transcription initiation by RNA polymerase II	involved_in	TAS
GO:0061469	Biological Process	regulation of type B pancreatic cell proliferation	involved_in	IEA
GO:0010033	Biological Process	response to organic substance	involved_in	IBA
GO:0009410	Biological Process	response to xenobiotic stimulus	involved_in	IEP
GO:0007165	Biological Process	signal transduction	involved_in	IBA
GO:0005923	Cellular Component	bicellular tight junction	located_in	IEA
GO:0000785	Cellular Component	chromatin	part_of	IDA
GO:0097128	Cellular Component	cyclin D1-CDK4 complex	part_of	IPI
GO:0097129	Cellular Component	cyclin D2-CDK4 complex	part_of	IPI
GO:0097130	Cellular Component	cyclin D3-CDK4 complex	part_of	IPI
GO:0000307	Cellular Component	cyclin-dependent protein kinase holoenzyme complex	part_of	IBA
GO:0000307	Cellular Component	cyclin-dependent protein kinase holoenzyme complex	part_of	IDA
GO:0005737	Cellular Component	cytoplasm	is_active_in	IBA
GO:0005829	Cellular Component	cytosol	located_in	IDA
GO:0005829	Cellular Component	cytosol	located_in	TAS
GO:0031965	Cellular Component	nuclear membrane	located_in	IDA
GO:0005730	Cellular Component	nucleolus	located_in	IDA
GO:0005654	Cellular Component	nucleoplasm	located_in	IDA
GO:0005654	Cellular Component	nucleoplasm	located_in	TAS
GO:0005634	Cellular Component	nucleus	is_active_in	IBA
GO:0005634	Cellular Component	nucleus	located_in	IDA
GO:0005667	Cellular Component	transcription regulator complex	part_of	IEA

Pathways

Name	DB	ID
Developmental Biology	Reactome	R-HSA-1266738
Reproduction	Reactome	R-HSA-1474165
Meiosis	Reactome	R-HSA-1500620
Signal Transduction	Reactome	R-HSA-162582
Cell Cycle	Reactome	R-HSA-1640170
Disease	Reactome	R-HSA-1643685
SCF(Skp2)-mediated degradation of p27/p21	Reactome	R-HSA-187577
Generic Transcription Pathway	Reactome	R-HSA-212436
Cellular responses to stress	Reactome	R-HSA-2262752
Oxidative Stress Induced Senescence	Reactome	R-HSA-2559580
Senescence-Associated Secretory Phenotype (SASP)	Reactome	R-HSA-2559582
Cellular Senescence	Reactome	R-HSA-2559583
Oncogene Induced Senescence	Reactome	R-HSA-2559585
RMTs methylate histone arginines	Reactome	R-HSA-3214858
Chromatin modifying enzymes	Reactome	R-HSA-3247509
Transcriptional regulation of white adipocyte differentiation	Reactome	R-HSA-381340
Mitotic G1 phase and G1/S transition	Reactome	R-HSA-453279
Chromatin organization	Reactome	R-HSA-4839726
Cyclin E associated events during G1/S transition	Reactome	R-HSA-69202
G1/S Transition	Reactome	R-HSA-69206
Cyclin D associated events in G1	Reactome	R-HSA-69231
G1 Phase	Reactome	R-HSA-69236
S Phase	Reactome	R-HSA-69242
Cell Cycle, Mitotic	Reactome	R-HSA-69278
Cyclin A:Cdk2-associated events at S phase entry	Reactome	R-HSA-69656
RNA Polymerase II Transcription	Reactome	R-HSA-73857
Gene expression (Transcription)	Reactome	R-HSA-74160
Ubiquitin-dependent degradation of Cyclin D	Reactome	R-HSA-75815
Signaling by PTK6	Reactome	R-HSA-8848021
PTK6 Regulates Cell Cycle	Reactome	R-HSA-8849470
Transcriptional regulation by RUNX2	Reactome	R-HSA-8878166
Cellular responses to stimuli	Reactome	R-HSA-8953897
Signaling by Non-Receptor Tyrosine Kinases	Reactome	R-HSA-9006927
Meiotic recombination	Reactome	R-HSA-912446
Transcriptional regulation of granulopoiesis	Reactome	R-HSA-9616222
Diseases of Cellular Senescence	Reactome	R-HSA-9630747
Evasion of Oncogene Induced Senescence Due to p16INK4A Defects	Reactome	R-HSA-9630750
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4	Reactome	R-HSA-9630791
Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6	Reactome	R-HSA-9630794
Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects	Reactome	R-HSA-9632693
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4	Reactome	R-HSA-9632697
Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6	Reactome	R-HSA-9632700
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects	Reactome	R-HSA-9659787
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)	Reactome	R-HSA-9661069
Diseases of mitotic cell cycle	Reactome	R-HSA-9675126
Diseases of cellular response to stress	Reactome	R-HSA-9675132
Aberrant regulation of mitotic cell cycle due to RB1 defects	Reactome	R-HSA-9687139
Drug-mediated inhibition of CDK4/CDK6 activity	Reactome	R-HSA-9754119
Sphingolipid metabolism in senescence (WP5121)	WikiPathways	WP5121_r119472
Integrated cancer pathway (WP1971)	WikiPathways	WP1971_r117762
Tumor suppressor activity of SMARCB1 (WP4204)	WikiPathways	WP4204_r123410
Measles virus infection (WP4630)	WikiPathways	WP4630_r123414
Breast cancer pathway (WP4262)	WikiPathways	WP4262_r123349
Thyroid stimulating hormone (TSH) signaling pathway (WP2032)	WikiPathways	WP2032_r122774
Bladder cancer (WP2828)	WikiPathways	WP2828_r119245
Melanoma (WP4685)	WikiPathways	WP4685_r123437
Glioblastoma signaling pathways (WP2261)	WikiPathways	WP2261_r123065
PPAR-alpha pathway (WP2878)	WikiPathways	WP2878_r116507
Cell cycle (WP179)	WikiPathways	WP179_r122978
Prader-Willi and Angelman syndrome (WP3998)	WikiPathways	WP3998_r123316
Nuclear receptors meta-pathway (WP2882)	WikiPathways	WP2882_r120815
DYRK1A (WP5180)	WikiPathways	WP5180_r122423
Retinoblastoma gene in cancer (WP2446)	WikiPathways	WP2446_r116593
Ovarian infertility (WP34)	WikiPathways	WP34_r124177
T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection (WP3863)	WikiPathways	WP3863_r121717
Circadian rhythm genes (WP3594)	WikiPathways	WP3594_r117682
Overlap between signal transduction pathways contributing to LMNA laminopathies (WP4879)	WikiPathways	WP4879_r123415
Small cell lung cancer (WP4658)	WikiPathways	WP4658_r124606
Spinal cord injury (WP2431)	WikiPathways	WP2431_r120812
DNA damage response (WP707)	WikiPathways	WP707_r124174
G1 to S cell cycle control (WP45)	WikiPathways	WP45_r123406
Pancreatic adenocarcinoma pathway (WP4263)	WikiPathways	WP4263_r123405
Head and neck squamous cell carcinoma (WP4674)	WikiPathways	WP4674_r123494
H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity (WP3969)	WikiPathways	WP3969_r123402
Non-small cell lung cancer (WP4255)	WikiPathways	WP4255_r123348
miRNA regulation of DNA damage response (WP1530)	WikiPathways	WP1530_r124175
Malignant pleural mesothelioma (WP5087)	WikiPathways	WP5087_r122659
PI3K-Akt signaling pathway (WP4172)	WikiPathways	WP4172_r122580

Transcripts

Accession	Version	MolecularType	Name	NCBI	Comments
NM_000075	4	mRNA	None	NC_000012	Reference