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CDK5

cyclin dependent kinase 5
General Information
Name cyclin dependent kinase 5
Alias
  • cyclin-dependent kinase 5
  • TPKII catalytic subunit
  • cell division protein kinase 5
  • cyclin-dependent-like kinase 5
  • epididymis secretory sperm binding protein
  • protein kinase CDK5 splicing
  • serine/threonine-protein kinase PSSALRE
  • tau protein kinase II catalytic subunit
Gene_family Cyclin dependent kinases
organism Homo sapiens
entrez_id 1020
location 7q36.1
transcript_count 2
exon_count 12
Location
by NCBI GRCh38.p14
Summary
    Entrez This gene encodes a proline-directed serine/threonine kinase that is a member of the cyclin-dependent kinase family of proteins. Unlike other members of the family, the protein encoded by this gene does not directly control cell cycle regulation. Instead the protein, which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons, functions in diverse processes such as synaptic plasticity and neuronal migration through phosphorylation of proteins required for cytoskeletal organization, endocytosis and exocytosis, and apoptosis. In humans, an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]
    Stringdb Cyclin-dependent-like kinase 5; Proline-directed serine/threonine-protein kinase essential for neuronal cell cycle arrest and differentiation and may be involved in apoptotic cell death in neuronal diseases by triggering abortive cell cycle re-entry. Interacts with D1 and D3- type G1 cyclins. Phosphorylates SRC, NOS3, VIM/vimentin, p35/CDK5R1, MEF2A, SIPA1L1, SH3GLB1, PXN, PAK1, MCAM/MUC18, SEPT5, SYN1, DNM1, AMPH, SYNJ1, CDK16, RAC1, RHOA, CDC42, TONEBP/NFAT5, MAPT/TAU, MAP1B, histone H1, p53/TP53, HDAC1, APEX1, PTK2/FAK1, huntingtin/HTT, ATM, MAP2, NEFH and NEFM. Regulates several ne [...]
    nextProt Proline-directed serine/threonine-protein kinase essential for neuronal cell cycle arrest and differentiation and may be involved in apoptotic cell death in neuronal diseases by triggering abortive cell cycle re-entry. Interacts with D1 and D3-type G1 cyclins. Phosphorylates SRC, NOS3, VIM/vimentin, p35/CDK5R1, MEF2A, SIPA1L1, SH3GLB1, PXN, PAK1, MCAM/MUC18, SEPT5, SYN1, DNM1, AMPH, SYNJ1, CDK16, RAC1, RHOA, CDC42, TONEBP/NFAT5, MAPT/TAU, MAP1B, histone H1, p53/TP53, HDAC1, APEX1, PTK2/FAK1, huntingtin/HTT, ATM, MAP2, NEFH and NEFM. Regulates several neuronal development and physiological processes including neuronal survival, migration and differentiation, axonal and neurite growth, synaptogenesis, oligodendrocyte differentiation, synaptic plasticity and neurotransmission, by phosphorylating key proteins. Negatively regulates the CACNA1B/CAV2.2 -mediated Ca(2+) release probability at hippocampal neuronal soma and synaptic terminals (By similarity). Activated by interaction with CDK5R1 (p35) and CDK5R2 (p39), especially in postmitotic neurons, and promotes CDK5R1 (p35) expression in an autostimulation loop. Phosphorylates many downstream substrates such as Rho and Ras family small GTPases (e.g. PAK1, RAC1, RHOA, CDC42) or microtubule-binding proteins (e.g. MAPT/TAU, MAP2, MAP1B), and modulates actin dynamics to regulate neurite growth and/or spine morphogenesis. Phosphorylates also exocytosis associated proteins such as MCAM/MUC18, SEPT5, SYN1, and CDK16/PCTAIRE1 as well as endocytosis associated proteins such as DNM1, AMPH and SYNJ1 at synaptic terminals. In the mature central nervous system (CNS), regulates neurotransmitter movements by phosphorylating substrates associated with neurotransmitter release and synapse plasticity; synaptic vesicle exocytosis, vesicles fusion with the presynaptic membrane, and endocytosis. Promotes cell survival by activating anti-apoptotic proteins BCL2 and STAT3, and negatively regulating of JNK3/MAPK10 activity. Phosphorylation of p53/TP53 in response to genotoxic and oxidative stresses enhances its stabilization by preventing ubiquitin ligase-mediated proteasomal degradation, and induces transactivation of p53/TP53 target genes, thus regulating apoptosis. Phosphorylation of p35/CDK5R1 enhances its stabilization by preventing calpain-mediated proteolysis producing p25/CDK5R1 and avoiding ubiquitin ligase-mediated proteasomal degradation. During aberrant cell-cycle activity and DNA damage, p25/CDK5 activity elicits cell-cycle activity and double-strand DNA breaks that precedes neuronal death by deregulating HDAC1. DNA damage triggered phosphorylation of huntingtin/HTT in nuclei of neurons protects neurons against polyglutamine expansion as well as DNA damage mediated toxicity. Phosphorylation of PXN reduces its interaction with PTK2/FAK1 in matrix-cell focal adhesions (MCFA) during oligodendrocytes (OLs) differentiation. Negative regulator of Wnt/beta-catenin signaling pathway. Activator of the GAIT (IFN-gamma-activated inhibitor of translation) pathway, which suppresses expression of a post-transcriptional regulon of proinflammatory genes in myeloid cells; phosphorylates the linker domain of glutamyl-prolyl tRNA synthetase (EPRS) in a IFN-gamma-dependent manner, the initial event in assembly of the GAIT complex. Phosphorylation of SH3GLB1 is required for autophagy induction in starved neurons. Phosphorylation of TONEBP/NFAT5 in response to osmotic stress mediates its rapid nuclear localization. MEF2 is inactivated by phosphorylation in nucleus in response to neurotoxin, thus leading to neuronal apoptosis. APEX1 AP-endodeoxyribonuclease is repressed by phosphorylation, resulting in accumulation of DNA damage and contributing to neuronal death. NOS3 phosphorylation down regulates NOS3-derived nitrite (NO) levels. SRC phosphorylation mediates its ubiquitin-dependent degradation and thus leads to cytoskeletal reorganization. May regulate endothelial cell migration and angiogenesis via the modulation of lamellipodia formation. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. The complex p35/CDK5 participates in the regulation of the circadian clock by modulating the function of CLOCK protein: phosphorylates CLOCK at 'Thr-451' and 'Thr-461' and regulates the transcriptional activity of the CLOCK-BMAL1 heterodimer in association with altered stability and subcellular distribution.
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
CDK5 BioGRID AFF4 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID CCNI GeneID BioGRID Affinity Capture-MS; Two-hybrid
CDK5 BioGRID C2CD5 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID TMEM94 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID EIF5B GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID FIBP GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID CCNB2 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID CCNK GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID SKP2 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID MLLT1 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID HMGB2 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID COX5B GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID CKS2 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID CKS1B GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID CABLES1 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID CABLES2 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
CDK5 BioGRID CCNB1 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID CCNA2 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID Spdye4a GeneID BioGRID Affinity Capture-Western
CDK5 BioGRID SPDYE1 GeneID BioGRID Affinity Capture-Western
CDK5 BioGRID TRIM67 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID TIPARP GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID CDK7 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID CCNF GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID CDKN1B GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
CDK5 BioGRID CCND3 GeneID BioGRID Affinity Capture-MS; Two-hybrid
CDK5 BioGRID CDK6 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID CCND2 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Two-hybrid
CDK5 BioGRID AHSG GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID AGL GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID MAPK15 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID POF1B GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID ZRANB1 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID CCT8 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID CCT4 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID CCT7 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID DCLK3 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID CCT3 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID TCP1 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID PTK2 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID CDK16 GeneID BioGRID Affinity Capture-MS; Biochemical Activity
CDK5 BioGRID PRKN GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity
CDK5 BioGRID DIABLO GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID orf3 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID PIP5K1C GeneID BioGRID Biochemical Activity
CDK5 BioGRID RND2 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID RAC3 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID RAC2 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID RAC1 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID RHOQ GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID CDC42 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID RHOH GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID RHOG GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID RND3 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID RHOB GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID RHOA GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID RHOU GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID RHOJ GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID RHOF GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID RHOD GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID RND1 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID H1-1 GeneID BioGRID Biochemical Activity
CDK5 BioGRID CCNI2 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID GRM5 GeneID BioGRID Affinity Capture-Western
CDK5 BioGRID CDKN1A GeneID BioGRID Affinity Capture-MS; Reconstituted Complex
CDK5 BioGRID CDK3 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID CDK2 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID CCNE1 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID CCND1 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID MDGA1 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID RSPRY1 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID UNC119B GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID CNPPD1 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID HECTD1 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID CDK20 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID TUSC2 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID CDC37 GeneID BioGRID Affinity Capture-MS; Two-hybrid
CDK5 BioGRID CCNO GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID CDK5R1 GeneID BioGRID Affinity Capture-Luminescence; Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Co-crystal Structure; FRET; Reconstituted Complex
CDK5 BioGRID CDK14 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID PCNA GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
CDK5 BioGRID TULP3 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID PPARG GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
CDK5 BioGRID BRD4 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID E7 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID BRCC3 GeneID BioGRID Affinity Capture-Western
CDK5 BioGRID INS GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID FASN GeneID BioGRID Negative Genetic
CDK5 BioGRID HSCB GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID LZTS2 GeneID BioGRID Proximity Label-MS
CDK5 BioGRID ANKRD55 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID GAPDH GeneID BioGRID Proximity Label-MS
CDK5 BioGRID FKBP5 GeneID BioGRID Affinity Capture-Western
CDK5 BioGRID FKBP4 GeneID BioGRID Affinity Capture-Western
CDK5 BioGRID DNMT1 GeneID BioGRID Affinity Capture-Western
CDK5 BioGRID TRIM59 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
CDK5 BioGRID MIB1 GeneID BioGRID Proximity Label-MS
CDK5 BioGRID SPDYE4 GeneID BioGRID Two-hybrid
CDK5 BioGRID SPDYA GeneID BioGRID Two-hybrid
CDK5 BioGRID TRIM28 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID MEOX2 GeneID BioGRID Two-hybrid
CDK5 BioGRID PGRMC1 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID PLEKHA4 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID MAPT GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
CDK5 BioGRID Dppa3 GeneID BioGRID Proximity Label-MS
CDK5 BioGRID GSK3B GeneID BioGRID Affinity Capture-Western
CDK5 BioGRID LRRK2 GeneID BioGRID Affinity Capture-Western
CDK5 BioGRID AATK GeneID BioGRID Affinity Capture-Western; Biochemical Activity
CDK5 BioGRID NRAS GeneID BioGRID Proximity Label-MS
CDK5 BioGRID EGFR GeneID BioGRID Affinity Capture-MS; Positive Genetic
CDK5 BioGRID AKT2 GeneID BioGRID Positive Genetic
CDK5 BioGRID BRD2 GeneID BioGRID Negative Genetic
CDK5 BioGRID PIK3CA GeneID BioGRID Positive Genetic
CDK5 BioGRID IGF1R GeneID BioGRID Positive Genetic
CDK5 BioGRID HMGA1 GeneID BioGRID Negative Genetic
CDK5 BioGRID NDUFA4L2 GeneID BioGRID Positive Genetic
CDK5 BioGRID LARP7 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID HEXIM1 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID RPTOR GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID EGLN3 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID HIF1AN GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID HHV8GK18_gp82 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID UBE2A GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
CDK5 BioGRID PIKFYVE GeneID BioGRID Biochemical Activity
CDK5 BioGRID SARNP GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID SEPTIN11 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID SCYL2 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID SH3GLB1 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID CHORDC1 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID GORASP2 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID DIS3 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID COPZ1 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID SUB1 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID PRCC GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID SEPTIN7 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID DRG1 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID AURKC GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID YBX3 GeneID BioGRID Reconstituted Complex; Two-hybrid
CDK5 BioGRID CDC25C GeneID BioGRID Biochemical Activity
CDK5 BioGRID CDC25B GeneID BioGRID Affinity Capture-Western; Biochemical Activity
CDK5 BioGRID CDC25A GeneID BioGRID Biochemical Activity
CDK5 BioGRID FZR1 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
CDK5 BioGRID NF2 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID STUB1 GeneID BioGRID Affinity Capture-Western
CDK5 BioGRID CEP128 GeneID BioGRID Proximity Label-MS
CDK5 BioGRID NUBP2 GeneID BioGRID Co-fractionation
CDK5 BioGRID FBXW11 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID RPE GeneID BioGRID Co-fractionation
CDK5 BioGRID NTRK1 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID HTR6 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID CCT5 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID CCT2 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID CCT6A GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID CHFR GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID CDK5 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID STIP1 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID CDK18 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID HSP90AB1 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID HSP90AA1 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID H1-5 GeneID BioGRID Biochemical Activity
CDK5 BioGRID GLUD1 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID TRAP1 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID UCHL1 GeneID BioGRID Affinity Capture-Western
CDK5 BioGRID ECT2 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID PSEN1 GeneID BioGRID Two-hybrid
CDK5 BioGRID GBP1 GeneID BioGRID Co-fractionation
CDK5 BioGRID APP GeneID BioGRID Reconstituted Complex
CDK5 BioGRID RNF32 GeneID BioGRID Two-hybrid
CDK5 BioGRID MAST1 GeneID BioGRID Two-hybrid
CDK5 BioGRID HTRA2 GeneID BioGRID Biochemical Activity
CDK5 BioGRID MBP GeneID BioGRID Biochemical Activity
CDK5 BioGRID ODF1 GeneID BioGRID Affinity Capture-Western
CDK5 BioGRID AMPH GeneID BioGRID Biochemical Activity
CDK5 BioGRID KIF26B GeneID BioGRID Biochemical Activity
CDK5 BioGRID RPL34 GeneID BioGRID Reconstituted Complex; Two-hybrid
CDK5 BioGRID RB1 GeneID BioGRID Biochemical Activity
CDK5 BioGRID DNM1 GeneID BioGRID Biochemical Activity
CDK5 BioGRID DAB1 GeneID BioGRID Biochemical Activity
CDK5 BioGRID H1-0 GeneID BioGRID Biochemical Activity
CDK5 BioGRID Nedd4 GeneID BioGRID Biochemical Activity; Reconstituted Complex
CDK5 BioGRID NEDD4L GeneID BioGRID Biochemical Activity
CDK5 BioGRID NEDD4 GeneID BioGRID Biochemical Activity; Reconstituted Complex
CDK5 BioGRID ALAS1 GeneID BioGRID Two-hybrid
CDK5 BioGRID BAG6 GeneID BioGRID Two-hybrid
CDK5 BioGRID Cdk1 GeneID BioGRID Affinity Capture-MS
CDK5 BioGRID TLN1 GeneID BioGRID Biochemical Activity
CDK5 BioGRID NES GeneID BioGRID Affinity Capture-Western; Biochemical Activity
CDK5 BioGRID Suds3 GeneID BioGRID Biochemical Activity
CDK5 BioGRID HDAC4 GeneID BioGRID Affinity Capture-Western
CDK5 Protein FSD1 GeneID HPRD
CDK5 Protein CABLES1 GeneID HPRD
CDK5 Protein CABLES2 GeneID HPRD
CDK5 Protein CDK5RAP1 GeneID HPRD
CDK5 Protein MIR9-1HG GeneID HPRD
CDK5 Protein SYNJ1 GeneID HPRD
CDK5 Protein SET GeneID HPRD
CDK5 Protein NES GeneID HPRD
CDK5 Protein PTPN2 GeneID HPRD
CDK5 Protein NDEL1 GeneID HPRD
CDK5 Protein PIP5K1C GeneID HPRD
CDK5 Protein CDC37 GeneID HPRD
CDK5 Protein WASF1 GeneID HPRD
CDK5 Protein GSK3B GeneID HPRD
CDK5 Protein PPP1R1B GeneID HPRD
CDK5 Protein CDK5R2 GeneID HPRD
CDK5 Protein CDK5R1 GeneID HPRD
CDK5 Protein DAB1 GeneID HPRD
CDK5 Protein STXBP1 GeneID HPRD
CDK5 Protein MAPK10 GeneID HPRD
CDK5 Protein PAK1 GeneID HPRD
CDK5 Protein DNM1 GeneID HPRD
CDK5 Protein GAK GeneID HPRD
CDK5 Protein PPP1R2 GeneID HPRD
CDK5 Protein CCNG1 GeneID HPRD
CDK5 Protein CSNK1D GeneID HPRD
CDK5 Protein CDKN1B GeneID HPRD
CDK5 Protein MEF2A GeneID HPRD
CDK5 Protein PURA GeneID HPRD
CDK5 Protein AMPH GeneID HPRD
CDK5 Protein SYN1 GeneID HPRD
CDK5 Protein CDK16 GeneID HPRD
CDK5 Protein DCX GeneID HPRD
CDK5 Protein TP53 GeneID HPRD
CDK5 Protein ERBB3 GeneID HPRD
CDK5 Protein SRC GeneID HPRD
CDK5 Protein ABL1 GeneID HPRD
CDK5 Protein STX1A GeneID HPRD
CDK5 Protein MAP2K1 GeneID HPRD
CDK5 Protein PCNA GeneID HPRD
CDK5 Protein MAPT GeneID HPRD
CDK5 Protein MAPT GeneID HPRD
CDK5 Protein MAPT GeneID HPRD
CDK5 Protein GRIN2A GeneID HPRD
CDK5 Protein FYN GeneID HPRD
CDK5 Protein EZR GeneID HPRD
CDK5 Protein CCND2 GeneID HPRD
CDK5 Protein CDK5 GeneID HPRD
CDK5 Protein CHN1 GeneID HPRD
CDK5 Protein APP GeneID HPRD
CDK5 Protein PSEN1 GeneID HPRD
CDK5 Protein ACTN1 GeneID HPRD
CDK5 BioGRID TP53 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
CDK5 BioGRID STX1A GeneID BioGRID Reconstituted Complex
CDK5 BioGRID CDK5RAP2 GeneID BioGRID Reconstituted Complex
CDK5 BioGRID STXBP1 GeneID BioGRID Affinity Capture-Western
CDK5 BioGRID PAK1 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
CDK5 BioGRID GAK GeneID BioGRID Affinity Capture-Western
CDK5 BioGRID NDEL1 GeneID BioGRID Biochemical Activity; Co-localization
CDK5 BioGRID LMTK2 GeneID BioGRID Reconstituted Complex; Two-hybrid
CDK5 Protein CDK5R1 GeneID BIND p35 interacts with Cdk5. This interaction was modeled on a demonstrated interaction between bovine p35 and human Cdk5.
CDK5 Protein CDK5R1 GeneID BIND Cdk5 interacts with p35.
StringDB
A B experiments database textmining combined score hadb nhadb
CDK5 RDX 0 0 184 207 1 1
CDK5 GPHN 0 0 283 282 1 1
CDK5 PIK3R1 0 0 111 164 1 1
CDK5 CX3CR1 0 0 150 168 1 1
CDK5 PGRMC1 270 0 0 382 1 1
CDK5 CRHR1 0 0 157 175 1 1
CDK5 CDKN1C 0 0 439 449 1 1
CDK5 CFD 0 0 280 280 1 1
CDK5 STK16 0 0 102 192 1 1
CDK5 GSKIP 0 0 106 190 1 1
CDK5 ZDHHC13 0 0 91 171 1 1
CDK5 HSPA4 0 0 325 355 1 1
CDK5 MIEF1 0 0 145 164 1 1
CDK5 ACHE 0 0 384 413 1 2
CDK5 PPARA 0 0 335 338 1 2
CDK5 ARHGEF9 0 0 381 398 1 1
CDK5 DLG5 0 0 0 238 1 1
CDK5 RPTOR 59 0 149 191 1 2
CDK5 HSPB3 0 0 174 173 1 1
CDK5 NES 678 0 983 994 1 2
CDK5 CHAT 0 0 321 352 1 1
CDK5 TUBD1 0 0 0 156 1 1
CDK5 HSP90B1 0 0 113 244 1 1
CDK5 RAC3 0 0 157 244 1 2
CDK5 MAPK9 0 0 294 158 1 2
CDK5 PPM1L 0 0 0 187 1 1
CDK5 PLK2 0 0 745 304 1 1
CDK5 OGG1 0 0 89 155 1 1
CDK5 CYCS 0 0 329 333 1 2
CDK5 NRP1 0 600 230 692 1 1
CDK5 PSKH2 0 0 0 163 1 1
CDK5 CSNK1A1L 0 0 0 171 1 1
CDK5 CHEK2 0 0 271 215 1 1
CDK5 POMC 0 0 181 181 1 1
CDK5 SLC1A2 0 0 177 177 1 1
CDK5 HTR6 270 0 862 899 1 1
CDK5 CASP9 0 0 261 266 1 2
CDK5 ITPR1 0 0 270 275 1 2
CDK5 FASN 62 0 138 156 1 2
CDK5 TIAM2 0 0 141 313 1 1
CDK5 ARFRP1 0 0 57 358 1 1
CDK5 GAK 270 0 891 569 1 1
CDK5 ADD2 0 0 170 188 1 1
CDK5 SH3GLB1 265 0 439 620 1 2
CDK5 SLIT1 0 0 103 161 1 1
CDK5 EGF 0 0 342 342 1 2
CDK5 NRXN2 0 0 181 181 1 1
CDK5 PPFIA3 0 0 283 457 1 1
CDK5 RNF19A 0 0 261 261 1 1
CDK5 FARP2 0 0 144 276 1 1
CDK5 SENP1 0 0 113 153 1 1
CDK5 SKP2 0 0 194 195 1 2
CDK5 AURKB 0 0 283 226 1 1
CDK5 MAPK8 0 0 391 168 1 2
CDK5 NISCH 0 0 147 166 1 1
CDK5 PTK2 0 0 335 150 1 2
CDK5 ADIPOQ 0 0 329 330 1 2
CDK5 ENO2 0 0 170 206 1 1
CDK5 MAP2K4 0 0 124 163 1 1
CDK5 PABPN1 0 0 0 157 1 1
CDK5 ACTN2 0 0 124 156 1 1
CDK5 SLA 0 0 90 159 1 1
CDK5 PAK2 0 0 101 179 1 1
CDK5 PRKAR1B 0 0 74 190 1 1
CDK5 CALCA 0 0 140 160 1 1
CDK5 RAPGEF1 0 0 283 325 1 1
CDK5 PXN 0 0 411 411 1 1
CDK5 HIST2H3PS2 0 0 370 382 1 1
CDK5 CDK5RAP3 0 0 604 638 1 1
CDK5 SESN2 0 0 0 207 1 2
CDK5 GRM3 0 0 113 168 1 1
CDK5 TNS1 0 0 432 453 1 1
CDK5 VR1 0 0 338 367 1 1
CDK5 MAPRE3 0 0 324 354 1 1
CDK5 PRNP 0 0 298 325 1 2
CDK5 DAPK3 0 0 181 207 1 2
CDK5 NR3C1 0 900 485 946 1 1
CDK5 GLUD1 217 0 0 217 1 1
CDK5 CHKA 0 0 338 338 1 1
CDK5 KCTD20 0 0 81 178 1 1
CDK5 RPS6KB2 0 0 0 180 1 2
CDK5 NEUROD6 0 0 135 163 1 1
CDK5 POLR2E 0 0 0 292 1 1
CDK5 HES5 0 0 297 297 1 1
CDK5 PPP1R10 0 0 134 173 1 1
CDK5 PDE4A 0 0 211 211 1 1
CDK5 FSD1 213 0 439 587 1 1
CDK5 HTR7 0 0 181 213 1 1
CDK5 LGALS4 0 0 444 444 1 1
CDK5 STK32A 0 0 0 175 1 1
CDK5 ZNF365 0 0 125 187 1 1
CDK5 MIEF2 0 0 160 159 1 1
CDK5 FKBP5 270 0 236 462 1 1
CDK5 NR3C2 0 0 91 294 1 1
CDK5 BCHE 0 0 310 343 1 1
CDK5 DRD2 0 0 327 421 1 1
CDK5 BSG 0 0 63 198 1 1
CDK5 PPP1CB 0 0 188 271 1 1
CDK5 ABCA1 0 0 195 195 1 2
CDK5 ALK 0 0 124 150 1 2
CDK5 ROCK2 0 0 284 190 1 1
CDK5 DCTN1 0 0 160 199 1 1
CDK5 IAPP 0 0 202 202 1 2
CDK5 CCNB3 0 0 136 187 1 1
CDK5 PAX6 0 0 201 221 1 1
CDK5 WNT1 0 0 107 196 1 2
CDK5 GBP1 271 0 0 271 1 1
CDK5 HTR1A 0 0 181 212 1 1
CDK5 SPAST 0 0 150 151 1 1
CDK5 RHOB 0 0 171 322 1 1
CDK5 MAP1B 0 0 530 540 1 2
CDK5 KIF20A 0 0 74 168 1 1
CDK5 CUX1 0 0 155 161 1 1
CDK5 H2AFX 0 0 182 200 1 1
CDK5 DNM2 0 0 193 374 1 1
CDK5 MAGI3 0 0 46 183 1 1
CDK5 SIRT6 0 0 294 306 1 2
CDK5 NEFL 0 0 436 505 1 1
CDK5 SGK494 0 0 74 154 1 1
CDK5 HDAC8 0 0 142 172 1 1
CDK5 FKBP4 270 0 630 735 1 1
CDK5 CDK6 0 900 560 917 1 2
CDK5 AGER 0 0 211 211 1 2
CDK5 HYOU1 0 0 95 152 1 1
CDK5 HIST1H4E 0 0 210 210 1 1
CDK5 YWHAG 0 0 173 207 1 1
CDK5 SLC24A2 0 0 94 156 1 1
CDK5 CNTNAP1 0 0 163 237 1 1
CDK5 KCNIP3 0 0 108 163 1 1
CDK5 EPHA4 0 900 704 928 1 1
CDK5 MAPKAPK2 0 0 154 257 1 1
CDK5 NRAP 0 0 57 159 1 1
CDK5 CDH1 0 0 241 240 1 2
CDK5 EFCAB1 0 0 81 181 1 1
CDK5 NEUROG2 0 0 281 281 1 1
CDK5 RMDN1 0 0 0 164 1 1
CDK5 ARPP21 0 0 120 361 1 1
CDK5 DDX55 0 0 0 189 1 1
CDK5 BUB1B 0 0 166 167 1 1
CDK5 CEP152 0 0 177 232 1 1
CDK5 VPS35 0 0 166 222 1 2
CDK5 CDK16 270 0 701 338 1 1
CDK5 FRK 0 0 158 173 1 1
CDK5 MACF1 0 0 134 515 1 1
CDK5 IL4 0 0 135 154 1 1
CDK5 CSNK2A2 0 0 213 191 1 1
CDK5 ANKRD55 270 0 45 321 1 1
CDK5 RAP1B 0 0 77 178 1 1
CDK5 SLC12A2 0 0 134 168 1 1
CDK5 SS18L1 0 0 54 159 1 1
CDK5 NUMB 0 0 246 280 1 1
CDK5 PGRMC2 0 0 0 189 1 1
CDK5 ADCY5 0 0 165 165 1 1
CDK5 EP300 0 0 283 297 1 2
CDK5 ABHD3 0 0 60 254 1 1
CDK5 MLLT4 0 0 108 169 1 1
CDK5 CNTF 0 0 167 179 1 1
CDK5 PIP5K1C 213 0 167 352 1 1
CDK5 TUBB3 0 0 212 396 1 1
CDK5 ROCK1 0 0 255 156 1 2
CDK5 VAMP2 0 0 309 331 1 1
CDK5 SNCAIP 0 0 195 248 1 2
CDK5 SMAD3 0 0 208 225 1 2
CDK5 DBN1 270 0 395 549 1 1
CDK5 CDC37 213 0 47 251 1 1
CDK5 CCL2 0 0 193 193 1 2
CDK5 ALB 0 0 373 457 1 2
CDK5 KIF16B 0 0 0 185 1 1
CDK5 CASP8 0 0 216 221 1 2
CDK5 SGK2 0 0 0 197 1 1
CDK5 OSBPL2 0 0 0 210 1 1
CDK5 KIF17 0 0 193 207 1 1
CDK5 CASP7 0 0 150 292 1 1
CDK5 STMN2 0 0 184 183 1 1
CDK5 CUL1 0 0 141 179 1 1
CDK5 MME 0 0 294 359 1 1
CDK5 UBXN2B 0 0 74 390 1 1
CDK5 CSNK1D 213 900 235 953 1 1
CDK5 ELAVL1 0 0 200 205 1 2
CDK5 NPAS1 0 0 74 274 1 1
CDK5 SNPH 0 0 113 154 1 1
CDK5 HOOK1 274 0 56 285 1 1
CDK5 SPTBN4 0 0 154 272 1 1
CDK5 PVALB 0 0 278 318 1 1
CDK5 ITGB1 0 0 125 178 1 1
CDK5 RAP2A 0 0 162 180 1 1
CDK5 SORBS3 0 0 90 187 1 1
CDK5 KAT2A 0 0 150 169 1 1
CDK5 FOSL1 0 0 150 173 1 1
CDK5 TFEB 0 0 123 165 1 2
CDK5 SPAG9 0 0 134 227 1 1
CDK5 KIF5A 0 0 102 183 1 1
CDK5 HSP90AA1 177 0 594 713 1 2
CDK5 PTGDR 0 0 157 189 1 1
CDK5 OPN4 0 0 0 239 1 1
CDK5 NENF 0 0 74 567 1 1
CDK5 HDAC4 270 0 261 487 1 2
CDK5 E2F7 0 0 184 189 1 1
CDK5 HPGDS 0 0 572 572 1 1
CDK5 TMTC1 0 0 156 170 1 1
CDK5 BACE2 0 0 327 327 1 1
CDK5 FRMPD3 0 0 0 321 1 1
CDK5 FBXW7 0 0 166 165 1 2
CDK5 SOX2 0 0 184 183 1 2
CDK5 NEUROD1 0 0 292 292 1 1
CDK5 ESYT1 0 0 75 211 1 1
CDK5 SFI1 0 0 51 303 1 1
CDK5 EPHA7 0 900 150 906 1 1
CDK5 SET 213 0 260 401 1 1
CDK5 RHOV 0 0 157 156 1 1
CDK5 KIF13A 0 0 47 294 1 1
CDK5 HTRA2 270 0 134 381 1 1
CDK5 CEBPA 0 0 181 181 1 1
CDK5 AATK 270 0 663 755 1 1
CDK5 SYT1 0 0 290 426 1 1
CDK5 PSEN1 213 0 661 763 1 2
CDK5 SPDYA 238 0 93 284 1 1
CDK5 PDCD10 0 0 258 258 1 1
CDK5 WDR13 0 0 95 170 1 1
CDK5 MUL1 0 0 91 273 1 2
CDK5 GPRIN1 0 0 157 330 1 1
CDK5 INS 0 0 517 517 1 2
CDK5 ACTB 0 0 502 548 1 2
CDK5 UBE2E1 0 0 107 159 1 1
CDK5 FOXG1 0 0 136 196 1 1
CDK5 NEFH 0 0 529 792 1 1
CDK5 MSN 0 0 231 230 1 1
CDK5 ENSG00000258555 0 0 150 182 1 1
CDK5 CAV2 0 0 134 151 1 1
CDK5 EPRS 270 0 150 371 1 1
CDK5 ARHGDIA 0 0 182 187 1 1
CDK5 TES 0 0 122 153 1 1
CDK5 CTTN 0 0 583 595 1 1
CDK5 STUB1 270 0 292 553 1 2
CDK5 DNMT1 270 0 829 870 1 2
CDK5 RANBP9 0 0 164 299 1 1
CDK5 SUB1 256 0 0 256 1 1
CDK5 KEAP1 0 0 142 235 1 2
CDK5 MMP9 0 0 194 194 1 2
CDK5 RND1 0 0 193 193 1 1
CDK5 MAPK3 0 0 556 179 1 2
CDK5 THY1 0 0 146 203 1 1
CDK5 CSNK1E 0 0 96 379 1 1
CDK5 SIRT3 0 0 283 311 1 2
CDK5 HIST1H4J 0 0 210 210 1 1
CDK5 SLC9A9 0 0 0 207 1 1
CDK5 GRASP 0 0 150 325 1 1
CDK5 SQSTM1 0 0 161 339 1 2
CDK5 CDKN1A 815 0 369 880 1 2
CDK5 SLC32A1 0 0 166 165 1 1
CDK5 ECT2 0 0 422 422 1 1
CDK5 GSR 0 0 170 169 1 1
CDK5 PLXNA3 0 600 150 683 1 1
CDK5 HSPA8 0 0 412 432 1 2
CDK5 GSN 0 0 164 164 1 1
CDK5 RHOA 0 0 457 581 1 2
CDK5 NUP93 0 0 0 212 1 1
CDK5 PARP1 0 0 216 226 1 2
CDK5 AR 0 0 520 523 1 2
CDK5 STX1A 270 0 479 626 1 1
CDK5 CRLF2 0 0 0 207 1 1
CDK5 TOMM40 0 0 135 153 1 1
CDK5 CCNY 0 0 336 636 1 1
CDK5 STX4 0 0 150 185 1 1
CDK5 AURKA 0 0 292 215 1 2
CDK5 TARDBP 0 0 244 267 1 2
CDK5 SYN1 213 0 564 744 1 1
CDK5 UBE2N 0 0 72 151 1 1
CDK5 PLXNA1 0 600 181 695 1 1
CDK5 CLASP2 0 0 244 268 1 1
CDK5 RHOQ 0 0 181 181 1 1
CDK5 NCKAP5L 0 0 86 398 1 1
CDK5 RHOG 0 0 165 165 1 1
CDK5 NIM1K 0 0 90 194 1 1
CDK5 RAB1A 0 0 107 156 1 1
CDK5 SEMA4A 0 0 301 301 1 1
CDK5 R3HDM1 0 0 0 188 1 1
CDK5 ESR2 0 0 167 171 1 1
CDK5 MS4A1 0 0 456 456 1 1
CDK5 SEMA4B 0 0 322 321 1 1
CDK5 CCT4 271 0 46 470 1 1
CDK5 SIRT7 0 0 285 297 1 2
CDK5 NEUROG1 0 0 144 207 1 1
CDK5 CCNB2 0 900 171 934 1 1
CDK5 IGDCC3 0 0 181 198 1 1
CDK5 ADORA2A 0 0 166 198 1 1
CDK5 RALB 0 0 156 157 1 2
CDK5 ROBO1 0 0 150 190 1 1
CDK5 GABARAPL1 0 0 96 287 1 2
CDK5 TUBA1B 0 0 0 225 1 1
CDK5 YWHAE 0 900 493 949 1 1
CDK5 CAPN2 0 650 323 777 1 2
CDK5 VCP 0 0 142 164 1 2
CDK5 ABI1 0 0 134 224 1 1
CDK5 GRIN2A 213 0 624 706 1 1
CDK5 FYN 213 800 677 890 1 1
CDK5 GOLGA2 0 900 246 921 1 1
CDK5 GRB2 0 0 261 286 1 1
CDK5 ANK1 0 0 345 393 1 1
CDK5 SHH 0 0 213 213 1 2
CDK5 CSNK1A1 0 0 210 325 1 1
CDK5 NCK2 0 0 143 162 1 1
CDK5 PRDX1 0 900 125 910 1 1
CDK5 SPTBN1 0 0 0 175 1 1
CDK5 MIB2 0 0 0 328 1 1
CDK5 BSN 0 0 267 267 1 2
CDK5 SOD1 0 0 391 489 1 2
CDK5 CABLES1 870 600 703 984 1 1
CDK5 FRMPD1 0 0 0 215 1 1
CDK5 CDC25C 270 900 218 943 1 2
CDK5 TBL1X 0 0 200 200 1 1
CDK5 CENPJ 0 0 282 294 1 1
CDK5 ARNT 0 0 55 150 1 2
CDK5 CETN2 0 0 103 154 1 1
CDK5 APBB1 0 0 325 339 1 1
CDK5 SEMA3G 0 0 321 321 1 1
CDK5 UCHL1 270 0 209 412 1 2
CDK5 GAP43 0 0 213 230 1 1
CDK5 SEPT4 0 0 67 212 1 1
CDK5 CLIP4 0 0 0 208 1 1
CDK5 IRS2 0 0 218 218 1 1
CDK5 CAMK1D 0 0 241 231 1 1
CDK5 ARHGEF2 0 0 66 279 1 1
CDK5 DLL1 0 0 267 267 1 1
CDK5 MFN1 0 0 261 309 1 2
CDK5 FRMPD4 0 0 0 649 1 1
CDK5 IGFBP3 0 0 92 180 1 2
CDK5 KCNK17 0 0 48 215 1 1
CDK5 ENSG00000270024 0 0 43 181 1 1
CDK5 TREM2 0 0 233 232 1 1
CDK5 PRKACB 0 0 82 232 1 1
CDK5 AGAP3 0 0 66 163 1 1
CDK5 ESYT2 0 0 48 161 1 1
CDK5 NCOA3 0 0 167 167 1 1
CDK5 PNCK 0 0 0 187 1 1
CDK5 AGRN 0 0 268 268 1 1
CDK5 SEPT5 0 0 265 422 1 1
CDK5 FZR1 675 0 108 705 1 1
CDK5 SERTAD2 0 0 101 236 1 1
CDK5 CRK 0 0 282 310 1 1
CDK5 TRIM3 0 0 150 264 1 1
CDK5 RIPK2 0 0 124 150 1 2
CDK5 NCKIPSD 0 0 108 427 1 1
CDK5 NEDD9 0 0 142 161 1 1
CDK5 INA 0 0 261 397 1 1
CDK5 GORASP2 129 0 158 248 1 1
CDK5 RTN4R 0 0 134 167 1 1
CDK5 HOOK2 0 0 310 309 1 1
CDK5 CCNA2 376 0 562 731 1 1
CDK5 NOS1 0 0 421 433 1 1
CDK5 CASP1 0 0 164 170 1 2
CDK5 MPZL1 0 0 60 204 1 1
CDK5 NCOA2 0 0 136 159 1 1
CDK5 PLAT 0 0 124 162 1 1
CDK5 SNCA 0 0 520 541 1 2
CDK5 NUP107 0 0 0 207 1 1
CDK5 CHEK1 0 0 293 176 1 2
CDK5 MAP2K3 0 0 113 185 1 1
CDK5 CDC20 0 0 235 282 1 1
CDK5 PLK5 0 0 0 189 1 1
CDK5 STXBP5 0 0 216 216 1 1
CDK5 HPCAL1 0 0 45 172 1 1
CDK5 PER2 0 0 67 204 1 1
CDK5 HSPA1A 0 0 95 158 1 1
CDK5 ICAM5 0 0 307 307 1 1
CDK5 AIF1 0 0 323 361 1 2
CDK5 ECE2 0 0 57 153 1 1
CDK5 FAM69B 0 0 95 191 1 1
CDK5 MST4 0 0 123 177 1 1
CDK5 CAV1 0 0 317 364 1 2
CDK5 KIF1B 0 0 90 243 1 1
CDK5 DPYSL2 0 800 799 963 1 1
CDK5 PHF13 0 0 502 587 1 1
CDK5 EARS2 0 0 136 159 1 1
CDK5 SLC8A2 0 0 142 190 1 1
CDK5 ARFGEF2 0 0 161 170 1 1
CDK5 CALB1 0 0 233 276 1 1
CDK5 KCNB2 0 0 134 197 1 1
CDK5 GRIN2C 0 0 155 193 1 1
CDK5 TNKS 0 0 96 312 1 1
CDK5 CDH17 0 0 447 447 1 1
CDK5 KIF11 0 0 187 201 1 1
CDK5 ACTR3 117 0 0 179 1 1
CDK5 BCL2L11 0 0 268 268 1 2
CDK5 TSEN2 0 0 61 162 1 1
CDK5 MAPK8IP2 0 0 66 248 1 1
CDK5 DAPK1 0 0 232 164 1 2
CDK5 STMN3 0 0 150 184 1 1
CDK5 PLCG1 0 0 178 228 1 1
CDK5 RHOT1 0 0 151 151 1 1
CDK5 AURKC 130 0 108 261 1 1
CDK5 CCT8 271 0 72 377 1 1
CDK5 JUN 0 900 732 972 1 2
CDK5 ITPR3 0 0 241 246 1 1
CDK5 GAPDH 94 0 464 515 1 2
CDK5 SMAD2 0 0 154 172 1 2
CDK5 TLR4 0 0 150 181 1 2
CDK5 TOPORS 0 0 66 158 1 1
CDK5 ENO1 0 0 107 156 1 1
CDK5 ABL1 213 900 694 938 1 1
CDK5 R3HDM2 0 0 0 188 1 1
CDK5 MAP6 0 0 125 236 1 1
CDK5 NF1 0 0 172 173 1 1
CDK5 HIST4H4 0 0 210 210 1 1
CDK5 NOS2 0 0 134 176 1 2
CDK5 KIF1A 0 0 293 412 1 1
CDK5 TSSK3 0 0 203 192 1 1
CDK5 MAP2K7 0 0 369 251 1 1
CDK5 TCF7L2 0 0 279 279 1 1
CDK5 TRAK1 0 0 108 189 1 1
CDK5 HDAC10 0 0 70 246 1 1
CDK5 KCNB1 0 0 241 245 1 2
CDK5 NEFM 0 0 421 457 1 1
CDK5 RD3 0 0 115 252 1 1
CDK5 JAG2 0 0 162 173 1 1
CDK5 RAP1A 0 0 95 157 1 1
CDK5 GABARAPL2 0 0 95 241 1 2
CDK5 TPO 0 0 243 243 1 1
CDK5 CASP6 0 0 218 223 1 1
CDK5 DPP3 0 0 57 189 1 1
CDK5 CACNA1G 0 0 108 262 1 1
CDK5 SLC9A1 0 0 96 193 1 1
CDK5 LRRCC1 0 0 90 242 1 1
CDK5 IGF2BP2 0 0 292 292 1 1
CDK5 CCNJ 0 0 57 203 1 1
CDK5 BUB1 0 0 192 197 1 1
CDK5 RELA 0 0 134 157 1 2
CDK5 BCL2L1 0 0 465 465 1 2
CDK5 TUBB4A 0 0 102 299 1 1
CDK5 MCPH1 0 0 246 251 1 1
CDK5 RNPS1 0 0 51 258 1 1
CDK5 DNMT3A 0 0 195 195 1 2
CDK5 NFKB1 0 0 106 172 1 2
CDK5 DNMT3B 0 0 147 180 1 1
CDK5 MAPK8IP1 0 0 232 454 1 1
CDK5 ALDOA 0 0 70 187 1 1
CDK5 FOXM1 0 0 143 175 1 1
CDK5 SH3GLB2 0 0 0 151 1 1
CDK5 NPEPPS 0 0 893 904 1 1
CDK5 CTNND1 0 0 154 153 1 1
CDK5 RAPGEF4 0 0 155 154 1 1
CDK5 ANXA5 0 0 241 240 1 2
CDK5 ZDHHC17 0 0 119 152 1 1
CDK5 CCNB1 676 900 393 983 1 1
CDK5 WASL 0 0 282 299 1 1
CDK5 GRIA2 0 0 370 442 1 1
CDK5 FGF21 0 0 157 156 1 2
CDK5 COMMD9 0 0 0 157 1 1
CDK5 FTO 0 0 205 205 1 2
CDK5 GRIA4 0 0 208 315 1 1
CDK5 SIAH1 0 0 123 176 1 1
CDK5 PLK1 0 0 377 217 1 2
CDK5 RELN 0 0 556 586 1 1
CDK5 FAM13A 0 0 0 187 1 1
CDK5 IQGAP1 0 0 132 163 1 1
CDK5 AGAP2 0 0 150 281 1 1
CDK5 SYNGR1 0 0 70 164 1 1
CDK5 PLEC 0 0 71 403 1 1
CDK5 COL25A1 0 0 504 504 1 1
CDK5 GRIK2 0 0 183 234 1 1
CDK5 OSBPL1A 0 0 49 308 1 1
CDK5 SIRT2 0 0 390 413 1 2
CDK5 CKAP5 0 0 74 654 1 1
CDK5 POU3F2 0 0 160 159 1 1
CDK5 RHOBTB2 0 0 193 277 1 1
CDK5 FIG4 0 0 112 204 1 1
CDK5 CREBBP 0 0 246 261 1 1
CDK5 CLIP1 0 0 180 179 1 1
CDK5 PPFIA1 0 0 243 411 1 1
CDK5 ARHGEF6 0 0 74 155 1 1
CDK5 BCL11B 0 0 180 179 1 1
CDK5 UBE2D3 0 0 54 246 1 1
CDK5 GRB10 0 0 74 174 1 1
CDK5 PDXK 0 0 212 294 1 1
CDK5 PRKACA 0 0 66 236 1 1
CDK5 CALB2 0 0 181 244 1 1
CDK5 KCNJ11 0 0 205 205 1 1
CDK5 SYT12 0 0 151 166 1 1
CDK5 EFNB1 0 0 126 161 1 1
CDK5 PIN4 0 0 66 164 1 1
CDK5 GSG2 0 0 136 155 1 1
CDK5 CREB1 0 0 563 608 1 2
CDK5 IFNG 0 0 141 194 1 2
CDK5 TUBB1 0 0 0 204 1 1
CDK5 NSF 0 0 141 195 1 2
CDK5 SH3KBP1 0 0 327 327 1 1
CDK5 GRM7 0 0 108 198 1 1
CDK5 IL6 0 0 334 343 1 2
CDK5 MPP5 0 0 0 225 1 1
CDK5 PPP1R12A 0 0 246 301 1 1
CDK5 PPP4C 0 0 181 347 1 1
CDK5 SEPT6 0 0 122 206 1 1
CDK5 PIK3C3 0 0 194 194 1 2
CDK5 SMN1 0 0 142 194 1 1
CDK5 CCNF 0 0 120 232 1 1
CDK5 E2F6 0 0 195 200 1 1
CDK5 PPFIA2 0 0 56 266 1 1
CDK5 UBE2A 270 0 0 272 1 1
CDK5 PLEK 0 0 193 248 1 1
CDK5 KCNMA1 0 0 150 200 1 1
CDK5 ENDOG 0 0 108 205 1 1
CDK5 STAT1 0 0 167 167 1 2
CDK5 BCL2L2-PABPN1 0 0 157 235 1 1
CDK5 ELAVL3 0 0 182 181 1 1
CDK5 GRM8 0 0 81 230 1 1
CDK5 ACTR2 0 0 132 155 1 1
CDK5 CCNC 129 0 325 530 1 1
CDK5 NOTCH1 0 0 371 382 1 2
CDK5 GRIP1 0 0 232 233 1 1
CDK5 TRAF4 0 0 70 231 1 1
CDK5 CRELD2 67 0 0 275 1 1
CDK5 NRP2 0 0 113 416 1 1
CDK5 PIDD1 0 0 54 170 1 1
CDK5 KAZN 0 0 56 203 1 1
CDK5 PSEN2 0 0 455 536 1 1
CDK5 CXCR4 0 0 170 202 1 2
CDK5 HIST1H4F 0 0 210 210 1 1
CDK5 E2F2 0 0 210 216 1 1
CDK5 POTEF 0 0 140 220 1 1
CDK5 DCTN2 0 0 247 265 1 1
CDK5 CALM1 0 0 181 421 1 1
CDK5 MTOR 0 0 515 515 1 2
CDK5 SYT7 0 0 184 251 1 1
CDK5 C14orf79 0 0 134 196 1 1
CDK5 TRIM59 270 0 0 281 1 1
CDK5 MYO5A 0 0 182 181 1 1
CDK5 TBR1 0 0 262 267 1 1
CDK5 TRIB2 0 0 0 202 1 1
CDK5 PSMB4 0 0 0 182 1 1
CDK5 APP 273 0 709 831 1 2
CDK5 MFN2 0 0 219 270 1 2
CDK5 EGR1 0 650 422 800 1 2
CDK5 DCAF6 0 0 0 245 1 1
CDK5 TRIM13 0 0 323 333 1 1
CDK5 CDC73 0 0 0 160 1 1
CDK5 LMTK2 270 0 421 559 1 1
CDK5 SCN1A 0 0 147 167 1 1
CDK5 TRPV1 0 0 338 367 1 2
CDK5 CTNNB1 0 0 646 672 1 2
CDK5 HRAS 0 0 362 407 1 2
CDK5 MAP1LC3A 0 0 60 155 1 2
CDK5 ASTN1 0 0 181 198 1 1
CDK5 CDK2 0 900 781 907 1 2
CDK5 DDX18 0 0 0 482 1 1
CDK5 IPO13 0 0 66 171 1 1
CDK5 KLC3 0 0 243 286 1 1
CDK5 CACNA1C 0 0 180 179 1 1
CDK5 XPO1 0 0 433 470 1 1
CDK5 CALD1 0 0 175 175 1 1
CDK5 DNM3 0 0 67 271 1 1
CDK5 ARC 0 0 336 340 1 2
CDK5 PLA2G4A 0 0 145 252 1 1
CDK5 RHO 0 0 140 204 1 2
CDK5 RHOBTB1 0 0 170 257 1 1
CDK5 DCLK3 289 0 451 374 1 1
CDK5 RUNDC3B 0 0 56 174 1 1
CDK5 SP1 0 0 174 173 1 2
CDK5 DLG2 0 0 288 460 1 1
CDK5 MAPKAPK5 0 0 120 202 1 1
CDK5 CCT5 271 0 57 325 1 1
CDK5 POLR1B 0 0 0 256 1 1
CDK5 RAB5A 0 0 228 288 1 2
CDK5 IL1B 0 0 335 335 1 2
CDK5 VRK1 0 0 150 202 1 1
CDK5 ISL1 0 0 150 183 1 1
CDK5 HIF1A 0 0 452 459 1 2
CDK5 NEDD4 0 0 181 191 1 2
CDK5 SIRT5 0 0 292 355 1 1
CDK5 KIAA0195 646 0 325 768 1 1
CDK5 POLR2C 0 0 0 213 1 1
CDK5 PHACTR3 0 0 95 157 1 1
CDK5 ATXN1 0 0 211 265 1 1
CDK5 SUMO2 0 0 193 248 1 1
CDK5 KCNQ1 0 0 163 163 1 1
CDK5 DOK7 0 0 231 248 1 1
CDK5 CXCL8 0 0 165 165 1 2
CDK5 ELAVL2 0 0 166 165 1 1
CDK5 KRT5 0 0 55 153 1 1
CDK5 DYNLL1 0 0 89 165 1 1
CDK5 TCF21 0 0 0 256 1 1
CDK5 GDNF 0 0 297 297 1 2
CDK5 STAT3 0 0 457 457 1 2
CDK5 ADAM9 0 0 180 191 1 1
CDK5 EZH2 0 0 194 214 1 2
CDK5 NCOA1 0 0 183 183 1 1
CDK5 ATP6V0D1 0 0 0 179 1 1
CDK5 DLGAP1 0 0 215 284 1 1
CDK5 CDK14 273 0 402 317 1 1
CDK5 SEMA3B 0 0 297 297 1 1
CDK5 HSCB 270 0 0 270 1 1
CDK5 CDH2 0 0 324 328 1 1
CDK5 CHN1 213 0 0 369 1 1
CDK5 HDAC6 0 0 324 452 1 2
CDK5 APAF1 0 0 181 181 1 2
CDK5 CCNI 270 0 962 973 1 1
CDK5 GPR156 0 0 82 165 1 1
CDK5 SEMA3C 0 0 310 309 1 1
CDK5 POLR3B 0 0 0 200 1 1
CDK5 HIST1H1B 270 0 69 327 1 1
CDK5 WASF3 0 0 167 218 1 1
CDK5 PAK1 270 900 305 937 1 2
CDK5 KARS 0 0 113 181 1 1
CDK5 NR4A1 0 0 193 198 1 2
CDK5 RPGR 0 0 53 226 1 1
CDK5 ADCY1 0 0 142 161 1 1
CDK5 CLU 0 0 230 229 1 2
CDK5 SEMA3D 0 0 310 309 1 1
CDK5 CALM3 0 0 151 413 1 1
CDK5 PCYT2 0 0 54 177 1 1
CDK5 BAG6 66 0 0 165 1 1
CDK5 PIN1 0 0 143 307 1 1
CDK5 NLGN1 0 0 150 178 1 1
CDK5 MPP7 0 0 0 226 1 1
CDK5 RBL1 0 0 215 215 1 1
CDK5 OSGEPL1 0 0 84 243 1 1
CDK5 KLC4 0 0 48 178 1 1
CDK5 VRK3 0 0 113 168 1 1
CDK5 NRXN3 0 0 181 181 1 1
CDK5 NTSR1 0 0 66 196 1 1
CDK5 NCOR2 0 0 156 191 1 1
CDK5 LMNA 0 900 181 915 1 2
CDK5 ARPC2 0 0 75 170 1 1
CDK5 PLP1 0 0 143 220 1 1
CDK5 ARF5 0 0 57 151 1 1
CDK5 PRKACG 0 0 0 220 1 1
CDK5 PRKX 0 0 108 191 1 1
CDK5 HDAC2 0 0 324 376 1 1
CDK5 EMX1 0 0 228 227 1 1
CDK5 PPP2R5D 0 0 308 323 1 1
CDK5 CAPNS2 0 650 0 650 1 1
CDK5 NGEF 0 0 577 589 1 1
CDK5 GUK1 0 0 74 173 1 1
CDK5 CKS1B 0 0 267 267 1 1
CDK5 SATB2 0 0 135 201 1 1
CDK5 EPS15 0 0 210 245 1 1
CDK5 SLC12A5 0 0 181 213 1 1
CDK5 MDM2 0 0 310 309 1 2
CDK5 LCN2 0 0 0 516 1 1
CDK5 TP53 462 900 508 971 1 2
CDK5 SOX18 0 0 47 180 1 1
CDK5 KIF5C 0 0 149 225 1 1
CDK5 ZNF17 0 0 107 196 1 1
CDK5 TUBA4A 0 0 144 305 1 1
CDK5 HIST1H4I 0 0 210 210 1 1
CDK5 EGFR 129 0 490 288 1 2
CDK5 CDK4 0 900 727 920 1 2
CDK5 CCS 0 0 297 297 1 2
CDK5 HTT 0 0 629 714 1 2
CDK5 PPP1CC 0 0 295 420 1 1
CDK5 METAP2 0 0 46 181 1 1
CDK5 EME1 0 0 146 207 1 1
CDK5 HOMER2 0 0 150 242 1 1
CDK5 NEDD8 0 0 100 154 1 2
CDK5 PPP1R1B 213 900 683 975 1 1
CDK5 RFC1 0 0 0 418 1 1
CDK5 AKT2 105 0 202 301 1 2
CDK5 CTNND2 0 0 213 213 1 1
CDK5 CDK20 284 0 418 355 1 1
CDK5 EHMT2 0 0 263 293 1 2
CDK5 NFE2L2 0 0 216 216 1 2
CDK5 PGAM5 0 0 64 168 1 1
CDK5 WDR62 0 0 212 261 1 1
CDK5 MICAL1 0 0 160 175 1 1
CDK5 MAP2K5 0 0 166 185 1 1
CDK5 MECP2 0 0 321 337 1 1
CDK5 VPS72 0 0 91 155 1 1
CDK5 MFF 0 0 143 154 1 1
CDK5 VASP 0 0 123 158 1 1
CDK5 ST13 0 0 241 246 1 2
CDK5 PLXNA2 0 600 456 824 1 1
CDK5 MAP2K1 213 900 413 936 1 1
CDK5 CHN2 0 0 0 150 1 1
CDK5 CDKN2D 0 0 286 348 1 1
CDK5 PPIF 0 0 138 156 1 1
CDK5 MAP3K8 0 0 0 156 1 1
CDK5 PCNT 0 0 162 168 1 1
CDK5 OPA1 0 0 158 202 1 2
CDK5 BRCA1 0 0 267 267 1 2
CDK5 FKBP7 0 0 218 224 1 1
CDK5 STK11 0 0 284 174 1 2
CDK5 SYNJ1 213 0 286 577 1 1
CDK5 DSP 0 0 0 302 1 1
CDK5 GRIN3B 0 0 64 167 1 1
CDK5 SYT13 0 0 134 150 1 1
CDK5 NPY 0 0 244 245 1 1
CDK5 CCNT1 0 0 324 391 1 1
CDK5 TRAK2 0 0 109 190 1 1
CDK5 HDAC5 0 0 294 363 1 1
CDK5 UBA1 0 0 113 199 1 1
CDK5 ANP32A 0 0 207 207 1 1
CDK5 FLNA 0 0 218 218 1 1
CDK5 HIST1H4L 0 0 210 210 1 1
CDK5 HDAC3 0 0 126 215 1 2
CDK5 MYCN 0 0 166 165 1 1
CDK5 PPP3CC 0 0 150 243 1 1
CDK5 MEF2D 0 0 418 442 1 2
CDK5 C9orf72 0 0 159 158 1 2
CDK5 ACTA1 0 0 73 159 1 1
CDK5 SHANK1 0 0 155 228 1 1
CDK5 PARK7 0 0 293 355 1 2
CDK5 EFNA5 0 900 180 915 1 1
CDK5 SEMA4C 0 0 322 321 1 1
CDK5 PARD3 0 0 123 154 1 1
CDK5 HIST1H1A 270 0 0 371 1 1
CDK5 CYFIP1 0 0 124 164 1 1
CDK5 SCN2A 0 0 162 182 1 1
CDK5 PPP3CB 0 0 193 281 1 1
CDK5 TUBA3E 0 0 0 222 1 1
CDK5 ARHGEF28 0 0 134 240 1 1
CDK5 DVL1 0 0 135 160 1 1
CDK5 SEMA6A 0 0 318 332 1 1
CDK5 NPC1 0 0 142 183 1 2
CDK5 GNAQ 0 0 144 170 1 1
CDK5 ADORA1 0 0 143 190 1 1
CDK5 MYLK4 0 0 0 158 1 1
CDK5 PIM1 0 0 73 172 1 1
CDK5 SPTBN2 0 0 71 200 1 1
CDK5 MAP2 0 0 455 715 1 2
CDK5 TUBA3D 0 0 0 222 1 1
CDK5 NR4A3 0 0 90 221 1 1
CDK5 TBC1D31 0 0 0 270 1 1
CDK5 ARHGAP1 0 0 134 189 1 1
CDK5 SYT11 0 0 156 276 1 1
CDK5 TOP1 0 0 243 259 1 1
CDK5 PIK3CA 105 0 138 195 1 2
CDK5 RALGDS 0 0 167 189 1 1
CDK5 NCSTN 0 0 391 640 1 1
CDK5 HTR1B 0 0 138 190 1 1
CDK5 PGA5 0 0 142 172 1 1
CDK5 PARK2 294 0 402 634 1 1
CDK5 CCNH 0 0 504 665 1 1
CDK5 CLOCK 0 0 113 209 1 2
CDK5 PURA 213 0 491 715 1 1
CDK5 ILK 0 0 232 316 1 1
CDK5 WNT5A 0 0 105 160 1 2
CDK5 SLC6A4 0 0 134 171 1 1
CDK5 LAMA5 0 0 48 177 1 1
CDK5 PPP5C 0 0 57 196 1 1
CDK5 APEX1 0 0 620 620 1 1
CDK5 STK32B 0 0 0 162 1 1
CDK5 TLN1 270 0 180 483 1 1
CDK5 SLC1A3 0 0 172 190 1 1
CDK5 MYC 0 0 413 412 1 2
CDK5 RAB3B 0 0 49 219 1 1
CDK5 PPARGC1A 0 0 365 369 1 2
CDK5 LARP7 270 0 0 271 1 1
CDK5 ADNP 0 0 134 168 1 1
CDK5 H1F0 270 0 602 753 1 1
CDK5 ADAM10 0 0 375 432 1 1
CDK5 UBE2D1 0 0 57 157 1 1
CDK5 TCERG1 0 0 123 214 1 1
CDK5 CAPN3 0 0 106 195 1 1
CDK5 KALRN 0 0 559 567 1 1
CDK5 IGF1R 105 0 212 185 1 2
CDK5 NLGN2 0 0 112 160 1 1
CDK5 MIB1 114 0 123 548 1 1
CDK5 IRF2BP2 0 0 177 177 1 1
CDK5 BICD2 0 0 181 222 1 1
CDK5 SEMA6C 0 0 323 337 1 1
CDK5 MANF 0 0 45 185 1 1
CDK5 PTPN1 0 0 161 193 1 1
CDK5 SLC6A3 0 0 294 294 1 1
CDK5 FUS 0 0 186 186 1 2
CDK5 GRM2 0 0 184 206 1 1
CDK5 CAPNS1 0 650 138 697 1 2
CDK5 XBP1 0 0 165 175 1 2
CDK5 TPPP 0 0 305 428 1 1
CDK5 MCF2 0 0 132 191 1 1
CDK5 GIT1 0 0 160 200 1 1
CDK5 PCNA 678 0 0 980 1 2
CDK5 CAMK1 0 0 269 238 1 1
CDK5 CRH 0 0 217 217 1 1
CDK5 GRIN1 0 0 240 487 1 1
CDK5 SYP 0 0 504 534 1 1
CDK5 DPYSL3 0 600 451 796 1 1
CDK5 CAMK2G 0 0 136 286 1 1
CDK5 PPP5D1 0 0 0 183 1 1
CDK5 APBA3 0 0 0 202 1 1
CDK5 WNT3A 0 0 129 183 1 2
CDK5 DYNC1H1 0 0 357 454 1 1
CDK5 KCTD19 0 0 0 296 1 1
CDK5 MAP2K6 0 0 134 190 1 1
CDK5 ATG5 0 0 171 267 1 2
CDK5 PIM2 0 0 108 209 1 1
CDK5 ESR1 0 0 315 318 1 2
CDK5 PDE10A 0 0 137 294 1 1
CDK5 PPP1CA 270 0 282 541 1 1
CDK5 RAC1 0 900 268 928 1 2
CDK5 ADCY8 0 0 149 224 1 1
CDK5 LYN 0 0 243 191 1 1
CDK5 UBE2D2 0 0 90 275 1 1
CDK5 PPA1 0 0 142 195 1 1
CDK5 COPS5 0 0 108 158 1 1
CDK5 PDIK1L 0 0 0 209 1 1
CDK5 PURB 0 0 0 226 1 1
CDK5 BACE1 0 0 698 698 1 2
CDK5 TUBB 0 0 134 312 1 1
CDK5 MAP3K4 0 0 83 211 1 1
CDK5 HOMER1 0 0 391 390 1 1
CDK5 TRPA1 0 0 160 213 1 1
CDK5 NPAS3 0 0 66 167 1 1
CDK5 EOMES 0 0 150 171 1 1
CDK5 MCL1 0 0 370 370 1 2
CDK5 KIF13B 0 0 287 560 1 1
CDK5 SMARCA4 0 0 170 169 1 1
CDK5 ELF4 0 0 52 195 1 1
CDK5 SIRT1 0 0 457 522 1 2
CDK5 KIF3A 0 0 148 189 1 1
CDK5 UBTF 0 0 59 205 1 1
CDK5 NOX1 0 0 321 321 1 1
CDK5 LMNB1 0 900 208 918 1 1
CDK5 CTSB 0 0 218 218 1 2
CDK5 PJA2 0 0 0 211 1 1
CDK5 MAPK8IP3 0 0 281 367 1 1
CDK5 AKT3 0 0 108 232 1 2
CDK5 DPYSL4 0 600 242 706 1 1
CDK5 ODF1 270 0 447 579 1 1
CDK5 CTNNA2 0 0 178 192 1 1
CDK5 DYNLL2 0 0 46 271 1 1
CDK5 BBS9 0 0 74 170 1 1
CDK5 RARS 0 0 99 350 1 1
CDK5 MUSK 0 0 243 225 1 1
CDK5 TBP 306 0 122 374 1 1
CDK5 FN1 0 0 254 254 1 2
CDK5 AP2S1 0 0 0 176 1 1
CDK5 RALA 0 0 282 283 1 1
CDK5 PKN1 0 0 262 153 1 1
CDK5 CAMK2A 0 0 367 368 1 2
CDK5 NUDC 0 0 103 305 1 1
CDK5 MAP4 0 0 107 234 1 1
CDK5 CDC25B 487 900 216 958 1 1
CDK5 NR2E3 0 0 53 157 1 1
CDK5 NEK2 0 0 181 169 1 1
CDK5 DST 0 0 53 541 1 2
CDK5 STMN1 0 0 325 325 1 1
CDK5 RPS6KA1 0 0 324 169 1 1
CDK5 MAPKAPK3 0 0 89 244 1 1
CDK5 CCNL2 0 0 134 216 1 1
CDK5 ADAM17 0 0 194 250 1 1
CDK5 PLXNB1 0 0 137 156 1 1
CDK5 MAP1LC3B 0 0 134 235 1 2
CDK5 KPTN 0 0 0 207 1 1
CDK5 SNAP91 0 0 293 377 1 1
CDK5 HOMER3 0 0 112 354 1 1
CDK5 CDK5RAP1 213 0 720 783 1 1
CDK5 YBX3 270 0 57 282 1 1
CDK5 HSPB2 0 0 181 202 1 1
CDK5 RAB3A 0 0 158 340 1 1
CDK5 ARL13B 0 0 48 151 1 1
CDK5 DYRK1A 0 0 652 225 1 1
CDK5 HSPB1 0 0 217 321 1 2
CDK5 PSKH1 0 0 55 153 1 1
CDK5 NDUFA8 0 0 0 211 1 1
CDK5 TGFBR1 0 0 101 228 1 1
CDK5 ZC3H14 0 0 357 360 1 1
CDK5 CNTLN 0 0 193 193 1 1
CDK5 IRAK4 0 0 46 199 1 1
CDK5 PLXNB3 0 0 123 217 1 1
CDK5 DAPK2 0 0 123 177 1 2
CDK5 ITGB4 0 0 73 154 1 1
CDK5 CABLES2 692 600 512 941 1 1
CDK5 PPARGC1B 0 0 85 180 1 1
CDK5 EFNB2 0 0 97 167 1 1
CDK5 IL10 0 0 173 173 1 2
CDK5 CDK7 270 900 681 934 1 1
CDK5 FMN1 0 0 95 186 1 1
CDK5 ASPM 0 0 231 236 1 1
CDK5 SEMA6B 0 0 323 323 1 1
CDK5 HHEX 0 0 233 232 1 1
CDK5 GFRA1 0 0 142 227 1 1
CDK5 NCK1 0 0 160 166 1 1
CDK5 GFAP 0 0 392 455 1 2
CDK5 ACTG1 0 0 181 257 1 1
CDK5 MICALL2 0 0 0 175 1 1
CDK5 DLG4 0 800 630 943 1 2
CDK5 PREX1 0 0 122 182 1 1
CDK5 DYRK1B 0 0 263 182 1 1
CDK5 SYT2 0 0 134 290 1 1
CDK5 ATG7 0 0 172 178 1 2
CDK5 FOSB 0 900 507 952 1 1
CDK5 TAC1 0 0 171 171 1 1
CDK5 MARCKS 0 0 200 200 1 1
CDK5 OGT 0 0 135 223 1 2
CDK5 MDM4 0 0 109 174 1 1
CDK5 SEMA3E 0 0 323 323 1 1
CDK5 NRGN 0 0 172 190 1 1
CDK5 EPHA6 0 900 0 902 1 1
CDK5 NRXN1 0 0 181 181 1 1
CDK5 TSEN34 0 0 57 169 1 1
CDK5 DRD5 0 0 0 221 1 1
CDK5 NTF4 0 0 203 203 1 1
CDK5 GAD2 0 0 161 179 1 1
CDK5 APMAP 0 0 66 209 1 1
CDK5 EZR 213 0 235 372 1 1
CDK5 SHC1 0 0 206 206 1 1
CDK5 KCNA2 0 0 145 164 1 1
CDK5 ATM 0 0 702 724 1 2
CDK5 CTSD 0 0 235 250 1 2
CDK5 AXIN1 0 0 284 328 1 1
CDK5 RAP1GAP 0 0 278 280 1 1
CDK5 NUB1 0 0 95 194 1 1
CDK5 AMPH 463 0 602 795 1 1
CDK5 IGF2 0 0 211 211 1 1
CDK5 AP2A1 0 0 72 183 1 1
CDK5 UCP1 0 0 141 162 1 2
CDK5 TSSK6 0 0 142 205 1 1
CDK5 HIST1H4K 0 0 210 210 1 1
CDK5 NGFR 0 0 234 235 1 1
CDK5 SARNP 256 0 0 256 1 1
CDK5 E2F3 0 0 232 238 1 1
CDK5 MARK2 0 0 423 169 1 1
CDK5 CHFR 270 0 0 285 1 1
CDK5 MAPK10 213 0 424 333 1 2
CDK5 HIST1H4A 0 0 210 210 1 1
CDK5 ENSG00000258947 0 0 194 429 1 1
CDK5 LMNB2 0 0 168 174 1 1
CDK5 MAPK14 0 0 341 185 1 2
CDK5 CFL1 0 0 459 488 1 1
CDK5 CNTN2 0 0 219 219 1 1
CDK5 KAT5 0 0 186 259 1 1
CDK5 LEP 0 0 240 239 1 1
CDK5 SYT5 0 0 150 376 1 1
CDK5 RPL34 270 0 113 328 1 1
CDK5 NFKBIA 0 0 143 200 1 2
CDK5 CCNA1 0 0 204 251 1 1
CDK5 ASTN2 0 0 82 180 1 1
CDK5 C12orf5 0 0 134 159 1 1
CDK5 MKLN1 0 0 228 228 1 1
CDK5 PPP1R9A 0 0 253 270 1 1
CDK5 CLIC4 0 0 329 329 1 1
CDK5 RIMS1 0 0 204 218 1 1
CDK5 EFHD2 0 0 219 236 1 1
CDK5 ISOC1 0 0 91 214 1 1
CDK5 PRKAA2 0 0 81 157 1 2
CDK5 E2F5 0 0 217 228 1 1
CDK5 DRD3 0 0 96 172 1 1
CDK5 NTRK3 0 0 142 215 1 1
CDK5 RUNDC3A 0 0 58 154 1 1
CDK5 MYOD1 0 0 154 153 1 1
CDK5 DNM1L 0 0 458 536 1 2
CDK5 CYFIP2 0 0 113 153 1 1
CDK5 PTEN 0 0 391 438 1 2
CDK5 ABHD1 0 0 67 169 1 1
CDK5 MBP 270 0 295 475 1 2
CDK5 GABARAP 0 0 123 308 1 2
CDK5 CHL1 0 0 181 181 1 1
CDK5 FSD1L 0 0 439 488 1 1
CDK5 MMEL1 0 0 0 176 1 1
CDK5 VEGFA 0 0 283 282 1 2
CDK5 HDAC9 0 0 203 274 1 1
CDK5 BRCA2 0 0 158 171 1 1
CDK5 KLC1 0 0 203 311 1 1
CDK5 PLD2 0 0 170 200 1 1
CDK5 SEPT2 0 0 95 251 1 1
CDK5 P2RX3 0 0 180 179 1 1
CDK5 UFL1 0 0 457 457 1 1
CDK5 RPE 272 0 0 304 1 1
CDK5 TUBE1 0 0 0 204 1 1
CDK5 ERBB3 213 0 180 263 1 1
CDK5 CASP3 0 0 608 615 1 2
CDK5 WASF2 0 0 320 382 1 1
CDK5 PTGS2 0 0 233 233 1 2
CDK5 EPHA5 0 900 108 904 1 1
CDK5 TUBB2B 0 0 113 292 1 1
CDK5 SMURF1 0 0 177 177 1 1
CDK5 TNFRSF21 0 0 164 163 1 1
CDK5 LIMK1 0 0 341 161 1 1
CDK5 TUBB6 0 0 74 231 1 1
CDK5 SH3GL2 0 0 185 206 1 1
CDK5 TNFRSF10B 0 0 90 157 1 2
CDK5 ZNF142 0 0 74 275 1 1
CDK5 NDE1 0 0 427 505 1 1
CDK5 RASGRF1 0 0 187 454 1 1
CDK5 ATG12 0 0 112 175 1 2
CDK5 STK17B 0 0 103 180 1 1
CDK5 BCAR1 0 0 181 181 1 1
CDK5 KIF2A 0 0 241 273 1 1
CDK5 ALOX5 0 0 262 278 1 1
CDK5 ABCA7 0 0 170 169 1 1
CDK5 PTPN5 0 0 224 236 1 1
CDK5 PSMA5 0 0 89 155 1 1
CDK5 BAIAP2 0 0 128 171 1 1
CDK5 GRM1 0 0 248 268 1 1
CDK5 ENSG00000268643 0 0 0 154 1 1
CDK5 PPME1 0 0 107 193 1 1
CDK5 SEPT7 265 0 164 410 1 1
CDK5 CYBB 0 0 296 296 1 2
CDK5 MYT1 0 0 71 156 1 1
CDK5 HDAC11 0 0 140 178 1 1
CDK5 DLG3 0 0 218 393 1 1
CDK5 TTR 0 0 134 151 1 1
CDK5 GSK3B 462 900 654 955 1 2
CDK5 GRIN3A 0 0 113 351 1 1
CDK5 BLK 0 0 112 167 1 1
CDK5 S100B 0 0 246 262 1 1
CDK5 PLXND1 0 0 155 174 1 1
CDK5 CCNG1 213 0 847 882 1 1
CDK5 TUBG1 0 0 164 297 1 1
CDK5 NUDT9 0 0 46 201 1 1
CDK5 PRCC 265 0 0 265 1 1
CDK5 VAT1L 0 0 108 197 1 1
CDK5 SFN 0 900 81 905 1 2
CDK5 FABP4 0 0 158 157 1 1
CDK5 GUSB 0 0 113 205 1 1
CDK5 UNC13B 0 0 150 158 1 1
CDK5 EPHA3 0 900 97 904 1 1
CDK5 CALM2 0 0 141 406 1 1
CDK5 CAPN10 0 0 157 175 1 2
CDK5 SST 0 0 161 179 1 1
CDK5 CDKN2A 0 0 378 419 1 2
CDK5 PPP6C 0 0 181 195 1 1
CDK5 KCNQ2 0 0 150 171 1 1
CDK5 SPAG16 0 0 0 270 1 1
CDK5 HIST2H4A 0 0 210 210 1 1
CDK5 KIF1C 0 0 0 185 1 1
CDK5 CUL3 0 0 165 245 1 2
CDK5 CACNA1H 0 0 124 211 1 1
CDK5 DAB1 463 0 95 592 1 1
CDK5 WNT2 0 0 100 238 1 1
CDK5 APBB2 0 0 203 220 1 1
CDK5 NTF3 0 0 260 265 1 1
CDK5 KIFAP3 0 0 390 390 1 1
CDK5 MEF2A 213 0 321 466 1 1
CDK5 CEBPB 0 0 167 167 1 2
CDK5 STK24 0 0 217 198 1 1
CDK5 NPAS4 0 0 242 241 1 1
CDK5 HCK 0 0 146 162 1 1
CDK5 TUBA8 0 0 117 274 1 1
CDK5 CDC123 0 0 181 181 1 1
CDK5 HDAC1 0 0 370 418 1 2
CDK5 PTGES3 0 0 153 160 1 1
CDK5 ABCB4 0 0 0 206 1 1
CDK5 YWHAH 0 0 173 191 1 1
CDK5 WNT3 0 0 103 159 1 1
CDK5 PHF1 0 0 617 640 1 1
CDK5 PRKAR1A 0 0 107 157 1 2
CDK5 APLP1 0 0 292 377 1 1
CDK5 RHOD 0 0 215 215 1 1
CDK5 CCT7 271 0 45 342 1 1
CDK5 FOS 0 0 470 496 1 2
CDK5 SV2A 0 0 182 199 1 1
CDK5 BIN3 0 0 0 152 1 1
CDK5 YWHAZ 0 0 166 197 1 1
CDK5 CRKL 0 0 159 191 1 1
CDK5 FRMD7 0 0 122 160 1 1
CDK5 PTPN11 0 0 181 194 1 1
CDK5 PPP1R1A 0 0 261 287 1 1
CDK5 MCM6 0 0 117 230 1 1
CDK5 DDX31 0 0 0 482 1 1
CDK5 RXRA 0 0 103 163 1 1
CDK5 ASCL1 0 0 206 206 1 1
CDK5 ARHGEF1 0 0 88 246 1 1
CDK5 TLN2 0 0 150 282 1 1
CDK5 PICALM 0 0 229 321 1 1
CDK5 DCC 0 0 161 168 1 1
CDK5 CAMK4 0 0 266 217 1 1
CDK5 LZTS2 297 0 0 297 1 1
CDK5 NRAS 128 0 108 221 1 1
CDK5 DNM1 463 0 581 820 1 1
CDK5 PDYN 0 0 334 334 1 1
CDK5 E2F1 0 0 253 312 1 2
CDK5 HSPA5 0 0 194 251 1 2
CDK5 TSSK4 0 0 0 156 1 1
CDK5 RND2 0 0 206 223 1 1
CDK5 SOD2 0 0 134 169 1 2
CDK5 CDK9 0 0 682 162 1 1
CDK5 CAPN8 0 0 57 151 1 1
CDK5 CACNA1I 0 0 84 175 1 1
CDK5 FOXO1 0 0 282 282 1 2
CDK5 KRAS 0 0 183 325 1 2
CDK5 WEE1 0 0 334 155 1 1
CDK5 PSENEN 0 0 369 400 1 1
CDK5 STXBP1 270 0 478 650 1 1
CDK5 LRP1 0 0 159 158 1 1
CDK5 ARF6 0 0 153 175 1 1
CDK5 MAPT 897 900 739 997 1 2
CDK5 BECN1 0 0 462 498 1 2
CDK5 MAOB 0 0 212 212 1 1
CDK5 CAMK2B 0 0 160 222 1 1
CDK5 ABCB1 0 0 124 218 1 2
CDK5 LRRK2 486 0 596 630 1 2
CDK5 ATXN3 0 0 210 210 1 2
CDK5 CDKN2C 0 0 241 291 1 1
CDK5 PICK1 0 0 248 263 1 1
CDK5 CHAF1A 0 0 0 189 1 1
CDK5 ELAVL4 0 0 168 186 1 1
CDK5 GRIN2B 0 0 902 907 1 1
CDK5 PLXNA4 0 600 129 675 1 1
CDK5 CCDC88A 0 0 233 246 1 1
CDK5 NTSR2 0 0 73 202 1 1
CDK5 MAPK11 0 0 136 153 1 1
CDK5 DUSP1 0 0 113 173 1 1
CDK5 PIM3 0 0 94 164 1 1
CDK5 PMAIP1 0 0 259 258 1 2
CDK5 CDKN2B 0 0 283 330 1 1
CDK5 APH1A 0 0 373 421 1 1
CDK5 TRIP10 0 0 122 187 1 1
CDK5 PAK4 0 0 157 175 1 1
CDK5 RAB3D 0 0 61 229 1 1
CDK5 CDC25A 270 900 257 946 1 1
CDK5 NAB2 0 650 101 677 1 1
CDK5 CNP 0 0 170 194 1 1
CDK5 ENSG00000251246 0 0 182 211 1 1
CDK5 TUBG2 0 0 0 184 1 1
CDK5 WAS 0 0 335 351 1 1
CDK5 GABBR1 0 0 143 161 1 1
CDK5 SIGMAR1 0 0 163 182 1 1
CDK5 UGP2 0 0 53 158 1 1
CDK5 ARHGAP35 0 0 203 208 1 1
CDK5 SEMA5A 0 0 310 327 1 1
CDK5 CDK5R1 981 900 985 999 1 1
CDK5 SCN8A 0 0 150 169 1 1
CDK5 APBA2 0 0 74 283 1 1
CDK5 DISC1 0 0 700 704 1 1
CDK5 E2F4 0 0 251 261 1 1
CDK5 MTNR1B 0 0 166 198 1 1
CDK5 PHKG2 0 0 45 185 1 1
CDK5 XIAP 0 0 229 235 1 2
CDK5 PPP2R4 0 0 562 571 1 1
CDK5 TMED10 0 0 323 323 1 1
CDK5 DLG1 0 0 142 334 1 1
CDK5 SPTB 0 0 0 175 1 1
CDK5 KATNA1 0 0 518 518 1 1
CDK5 SEMA6D 0 0 318 332 1 1
CDK5 KCNAB2 0 0 225 253 1 1
CDK5 NTRK2 0 600 466 733 1 1
CDK5 PPFIA4 0 0 0 254 1 1
CDK5 CDK8 0 900 466 905 1 1
CDK5 THRAP3 0 0 445 445 1 1
CDK5 ATF6 0 0 151 150 1 2
CDK5 PHKG1 0 0 0 185 1 1
CDK5 SGK3 0 0 53 184 1 1
CDK5 TUBA3C 0 0 0 222 1 1
CDK5 SYNJ2 0 0 0 234 1 1
CDK5 CDK18 274 0 506 323 1 1
CDK5 SUMO1 0 0 212 240 1 1
CDK5 WDTC1 0 0 0 245 1 1
CDK5 CD4 0 0 160 159 1 2
CDK5 ATF4 0 0 139 160 1 2
CDK5 SYT4 0 0 142 256 1 1
CDK5 CCNYL1 0 0 123 519 1 1
CDK5 SEMA7A 0 0 300 300 1 1
CDK5 SCN9A 0 0 189 199 1 1
CDK5 AKT1 0 0 674 381 1 2
CDK5 DDX10 0 0 0 482 1 1
CDK5 PPP1R9B 0 0 406 419 1 1
CDK5 CAPN1 0 650 470 825 1 2
CDK5 FIBP 872 0 350 932 1 1
CDK5 HIST1H4C 0 0 210 210 1 1
CDK5 PPARG 675 0 927 975 1 2
CDK5 UBE3A 0 0 141 181 1 1
CDK5 EFNB3 0 0 160 159 1 1
CDK5 GRIK1 0 0 108 163 1 1
CDK5 FBN2 0 0 148 154 1 1
CDK5 CES5A 0 0 0 206 1 1
CDK5 LHX2 0 0 107 198 1 1
CDK5 NGF 0 0 517 550 1 2
CDK5 NDOR1 0 0 0 151 1 1
CDK5 ENSG00000274276 0 0 181 211 1 1
CDK5 TUBAL3 0 0 0 211 1 1
CDK5 HMGA2 0 0 73 209 1 1
CDK5 TRIM2 0 0 0 195 1 1
CDK5 YES1 0 0 107 153 1 1
CDK5 DENR 0 0 186 192 1 1
CDK5 C2CD5 765 0 757 940 1 1
CDK5 TH 0 0 360 400 1 2
CDK5 ITM2B 0 0 0 175 1 1
CDK5 IGF2R 0 0 104 177 1 1
CDK5 VLDLR 0 0 324 323 1 1
CDK5 NR1I2 0 0 138 171 1 1
CDK5 CCNE2 0 0 213 474 1 1
CDK5 ENSA 0 0 86 202 1 1
CDK5 TSN 0 0 0 205 1 1
CDK5 PAFAH1B2 0 0 306 306 1 1
CDK5 SYNGAP1 0 0 265 293 1 1
CDK5 DSTN 0 0 46 152 1 1
CDK5 CREM 0 0 113 174 1 1
CDK5 GATM 0 0 0 297 1 1
CDK5 ANK3 0 0 404 457 1 1
CDK5 CRELD1 0 0 0 175 1 1
CDK5 HSP90AB1 177 0 54 356 1 2
CDK5 RHOC 0 0 167 358 1 1
CDK5 SPON1 0 0 140 159 1 1
CDK5 PIKFYVE 270 0 61 285 1 2
CDK5 RTN4 0 0 162 168 1 1
CDK5 ZNHIT2 0 0 69 416 1 1
CDK5 ARHGEF15 0 0 181 191 1 1
CDK5 CCNG2 0 0 95 326 1 1
CDK5 PHGDH 0 0 218 218 1 1
CDK5 CEP63 0 0 103 158 1 1
CDK5 GRM5 0 0 320 352 1 1
CDK5 PINK1 0 0 335 489 1 2
CDK5 NFATC4 0 0 136 227 1 1
CDK5 FAAH 0 0 66 321 1 1
CDK5 GSK3A 0 0 323 163 1 1
CDK5 MAG 0 0 245 261 1 1
CDK5 PPP3CA 0 0 170 260 1 1
CDK5 SIRT4 0 0 284 296 1 1
CDK5 GJA1 0 0 181 181 1 1
CDK5 PPA2 0 0 194 230 1 1
CDK5 HNF4A 0 0 193 193 1 1
CDK5 ENAH 0 0 59 171 1 1
CDK5 COMT 0 0 140 165 1 1
CDK5 TEN1-CDK3 610 0 601 635 1 1
CDK5 STK25 0 0 207 188 1 1
CDK5 DPYS 0 0 122 219 1 1
CDK5 A2M 0 0 145 164 1 1
CDK5 HTR2A 0 0 137 192 1 1
CDK5 LRPAP1 0 0 204 207 1 1
CDK5 UBE2C 0 0 89 151 1 1
CDK5 GAD1 0 0 442 454 1 1
CDK5 TUBB8B 0 0 0 243 1 1
CDK5 TRUB1 0 0 74 160 1 1
CDK5 SEMA4F 0 0 322 321 1 1
CDK5 TUBB8 0 0 0 257 1 1
CDK5 DIXDC1 0 0 267 297 1 1
CDK5 CDKN3 0 0 252 264 1 1
CDK5 TRIM28 270 0 69 302 1 2
CDK5 ARPP19 0 0 150 314 1 1
CDK5 CIB1 0 0 181 212 1 1
CDK5 DNAJB1 0 0 146 152 1 2
CDK5 SLC30A8 0 0 266 266 1 1
CDK5 CAMK2D 0 0 81 272 1 1
CDK5 TXNDC9 0 0 213 213 1 1
CDK5 CADM1 0 0 132 154 1 1
CDK5 SRC 213 0 556 411 1 2
CDK5 PRSS50 0 0 193 210 1 1
CDK5 SORL1 0 0 284 284 1 1
CDK5 STIL 0 0 181 212 1 1
CDK5 CDC42 0 0 585 660 1 2
CDK5 ATAD5 0 0 0 207 1 1
CDK5 CCNI2 270 0 347 532 1 1
CDK5 TUBA1C 0 0 75 266 1 1
CDK5 CRTC1 0 0 124 164 1 2
CDK5 LRP8 0 0 391 390 1 1
CDK5 MKL1 0 0 210 210 1 1
CDK5 CCT3 271 0 46 331 1 1
CDK5 ACTG2 0 0 63 150 1 1
CDK5 CRIP2 0 0 0 223 1 1
CDK5 SPTAN1 0 0 256 256 1 1
CDK5 APOE 0 0 504 504 1 2
CDK5 RAPGEF2 0 0 266 293 1 1
CDK5 YWHAB 0 0 181 234 1 1
CDK5 KIF5B 0 0 122 191 1 1
CDK5 ATXN2 0 0 103 169 1 1
CDK5 SLC2A4 0 0 277 277 1 1
CDK5 NEXN 0 0 210 210 1 1
CDK5 FOXO3 0 900 244 927 1 2
CDK5 CUX2 0 0 113 174 1 1
CDK5 TRMT5 0 0 123 295 1 1
CDK5 RB1 270 0 171 368 1 2
CDK5 HEXIM1 270 0 71 292 1 1
CDK5 PURG 0 0 0 213 1 1
CDK5 CAMK1G 0 0 45 180 1 1
CDK5 CRMP1 0 600 503 819 1 1
CDK5 APLP2 0 0 261 423 1 1
CDK5 IRX6 0 0 52 151 1 1
CDK5 LAMA3 0 0 0 294 1 1
CDK5 HAP1 0 0 113 185 1 1
CDK5 CDKN1B 870 0 859 981 1 2
CDK5 GLUL 0 0 151 165 1 1
CDK5 TIAM1 0 650 254 782 1 1
CDK5 ADORA2B 0 0 136 169 1 1
CDK5 TPRA1 0 0 120 154 1 1
CDK5 DLC1 0 0 141 175 1 2
CDK5 RAB7B 0 0 117 163 1 1
CDK5 RASGRF2 0 0 248 361 1 1
CDK5 TSC2 0 0 166 184 1 2
CDK5 GORASP1 0 0 360 371 1 1
CDK5 CDKAL1 0 0 675 691 1 1
CDK5 DIS3 261 0 0 261 1 1
CDK5 VDAC1 0 0 195 195 1 2
CDK5 POLR2B 0 0 0 200 1 1
CDK5 TGFB1 0 0 123 165 1 2
CDK5 TRIT1 0 0 122 216 1 1
CDK5 PACSIN1 0 0 224 240 1 1
CDK5 MARCH5 0 0 155 154 1 1
CDK5 RAB11A 0 0 234 250 1 2
CDK5 RAC2 0 0 174 237 1 1
CDK5 SEMA3F 0 0 310 309 1 1
CDK5 WASF1 213 0 648 741 1 1
CDK5 LCOR 0 0 0 163 1 1
CDK5 EIF2S1 0 0 161 184 1 2
CDK5 NTN1 0 0 245 252 1 1
CDK5 SKP1 0 0 150 163 1 2
CDK5 RASSF1 0 0 47 154 1 1
CDK5 MOS 0 0 0 185 1 1
CDK5 EPB41 0 0 181 181 1 1
CDK5 CACNA1A 0 0 346 346 1 1
CDK5 HIST1H4D 0 0 210 210 1 1
CDK5 HMOX1 0 0 162 161 1 2
CDK5 SLC17A7 0 0 235 251 1 1
CDK5 TCHP 0 0 294 294 1 1
CDK5 CEND1 0 0 124 178 1 1
CDK5 BIN1 0 0 682 724 1 1
CDK5 TUBB2A 0 0 123 315 1 1
CDK5 LRRK1 0 0 0 158 1 1
CDK5 DCX 213 0 503 593 1 1
CDK5 NRG1 0 0 218 218 1 2
CDK5 CAT 0 0 181 186 1 2
CDK5 CCNK 0 0 256 359 1 1
CDK5 ANK2 0 0 123 201 1 1
CDK5 IDE 0 0 468 497 1 1
CDK5 PTK2B 0 0 261 154 1 1
CDK5 KLC2 0 0 253 314 1 1
CDK5 TSSK2 0 0 0 172 1 1
CDK5 PDPK1 0 0 170 173 1 2
CDK5 NUBP2 272 0 56 283 1 1
CDK5 S100A10 0 0 45 216 1 1
CDK5 CCNE1 682 0 627 954 1 1
CDK5 CAST 0 650 451 803 1 2
CDK5 NDUFA13 0 0 56 166 1 1
CDK5 RASA1 0 0 134 225 1 1
CDK5 OPRM1 0 0 338 364 1 1
CDK5 MECOM 0 0 167 173 1 1
CDK5 STAU2 0 0 125 231 1 1
CDK5 TXN 0 0 180 186 1 1
CDK5 GRIA1 0 0 520 584 1 1
CDK5 CCT6A 271 0 53 322 1 1
CDK5 GRIK5 0 0 93 167 1 1
CDK5 MAGI2 0 0 123 195 1 1
CDK5 STXBP3 0 0 155 187 1 1
CDK5 AP2B1 0 0 170 171 1 1
CDK5 NUMBL 274 0 66 325 1 1
CDK5 MCM7 0 0 151 157 1 1
CDK5 ITSN1 0 0 194 349 1 1
CDK5 SMN2 0 0 134 187 1 1
CDK5 HPCA 0 0 74 171 1 1
CDK5 PTPN2 213 0 46 269 1 2
CDK5 HIST2H4B 0 0 210 210 1 1
CDK5 BCL2 0 0 72 216 1 2
CDK5 SEMA5B 0 0 323 340 1 1
CDK5 MAP2K2 0 0 162 193 1 1
CDK5 E2F8 0 0 210 215 1 1
CDK5 CHORDC1 261 0 45 264 1 1
CDK5 DCLK2 0 0 170 152 1 1
CDK5 PPP2R3A 0 0 209 209 1 1
CDK5 GNB2L1 0 0 190 208 1 1
CDK5 TUBA1A 0 0 155 314 1 1
CDK5 NDEL1 463 900 567 978 1 1
CDK5 SEMA4G 0 0 323 323 1 1
CDK5 PACS1 0 0 57 157 1 1
CDK5 NUP88 0 0 0 207 1 1
CDK5 KLF9 0 0 143 166 1 1
CDK5 VPRBP 0 0 0 181 1 1
CDK5 EFNA1 0 0 268 268 1 1
CDK5 SYNM 0 0 171 215 1 1
CDK5 SFMBT2 0 0 0 222 1 1
CDK5 ARHGEF7 0 0 134 208 1 1
CDK5 LRGUK 0 0 0 151 1 1
CDK5 CACNA1B 0 0 393 392 1 1
CDK5 ALDOC 0 0 54 216 1 1
CDK5 MTF2 0 0 174 190 1 1
CDK5 CD274 0 0 195 195 1 2
CDK5 BRK1 0 0 164 176 1 1
CDK5 CCND1 391 0 939 964 1 2
CDK5 RCC1 0 0 144 176 1 1
CDK5 HDAC7 0 0 124 269 1 1
CDK5 NOS3 0 0 207 224 1 2
CDK5 ACOT7 0 0 75 179 1 1
CDK5 ULK3 0 0 94 178 1 2
CDK5 SEMA3A 0 600 506 793 1 1
CDK5 CDK5RAP2 270 0 515 721 1 1
CDK5 JUND 0 900 165 913 1 1
CDK5 ACTN1 213 0 872 895 1 1
CDK5 FOXC2 0 0 466 466 1 1
CDK5 AKAP5 0 0 171 191 1 1
CDK5 UBE2I 0 0 170 194 1 1
CDK5 DPYSL5 0 600 246 707 1 1
CDK5 WNT9A 0 0 74 153 1 1
CDK5 BCL2L2 0 0 170 169 1 1
CDK5 SPTBN5 0 0 0 175 1 1
CDK5 FAM58A 0 0 75 191 1 1
CDK5 NTRK1 63 0 324 284 1 1
CDK5 KCNA1 0 0 161 185 1 1
CDK5 IRS1 0 0 247 246 1 2
CDK5 SYN3 0 0 308 479 1 1
CDK5 SGK1 0 0 266 251 1 2
CDK5 HSPA9 0 0 136 205 1 1
CDK5 DRD1 0 0 335 459 1 1
CDK5 ACTR10 0 0 46 213 1 1
CDK5 BAD 0 0 58 161 1 2
CDK5 TTBK1 0 0 421 425 1 1
CDK5 RPS6KB1 0 0 325 262 1 2
CDK5 OLIG2 0 0 203 203 1 1
CDK5 YWHAQ 0 0 563 576 1 1
CDK5 REM1 0 0 0 208 1 1
CDK5 KAT2B 0 0 451 451 1 1
CDK5 HIST1H4B 0 0 210 210 1 1
CDK5 NCOR1 0 0 293 293 1 1
CDK5 CDK1 0 900 739 907 1 2
CDK5 PPP2CA 0 0 362 376 1 1
CDK5 PER1 0 0 0 154 1 1
CDK5 AHR 0 0 106 250 1 2
CDK5 HIST2H2BE 0 0 161 173 1 1
CDK5 MAPK1 0 0 468 166 1 2
CDK5 PPP2R1A 0 0 113 188 1 1
CDK5 ITIH4 0 0 212 212 1 1
CDK5 IGF1 0 0 341 343 1 2
CDK5 UVRAG 0 0 162 208 1 2
CDK5 SEPT11 234 0 0 308 1 1
CDK5 EFNA3 0 0 167 216 1 1
CDK5 CCND3 787 0 328 878 1 1
CDK5 GRIA3 0 0 162 258 1 1
CDK5 SYNE1 0 0 66 161 1 1
CDK5 ARNTL 0 0 112 167 1 1
CDK5 KIF26B 270 0 74 307 1 1
CDK5 CNR1 0 0 216 246 1 1
CDK5 CCT2 271 0 74 339 1 1
CDK5 APBA1 0 0 261 427 1 1
CDK5 CASK 0 0 187 216 1 1
CDK5 ATF3 0 0 150 157 1 2
CDK5 CDK5R2 213 900 736 988 1 1
CDK5 PARD6A 0 0 150 173 1 1
CDK5 RAB3C 0 0 0 215 1 1
CDK5 FGF2 0 0 262 262 1 2
CDK5 REST 0 0 170 193 1 2
CDK5 RAB7A 0 0 122 210 1 2
CDK5 ITSN2 0 0 52 235 1 1
CDK5 FNBP1L 0 0 113 168 1 1
CDK5 CSNK2A1 0 0 394 194 1 1
CDK5 FKBP1C 0 0 219 225 1 1
CDK5 GPS2 0 0 160 159 1 1
CDK5 PLEKHA4 270 0 0 270 1 1
CDK5 RAPSN 0 0 261 337 1 1
CDK5 PRDX2 0 900 312 930 1 1
CDK5 IGFBP6 0 0 74 239 1 1
CDK5 TFAP2A 192 0 123 261 1 1
CDK5 CACNG2 0 0 195 209 1 1
CDK5 RHOF 0 0 156 155 1 1
CDK5 HIST1H4H 0 0 210 210 1 1
CDK5 CCND2 870 0 293 921 1 1
CDK5 GSTP1 0 0 264 264 1 1
CDK5 TCP1 217 0 55 273 1 1
CDK5 RND3 0 0 190 207 1 1
CDK5 ARX 0 0 74 167 1 1
CDK5 ARHGAP24 0 0 52 194 1 1
CDK5 AP2A2 0 0 0 155 1 1
CDK5 PLXNB2 0 0 134 164 1 1
CDK5 GCG 0 0 156 155 1 1
CDK5 FMR1 0 0 242 262 1 1
CDK5 CBSL 0 0 181 211 1 1
CDK5 RBFOX3 0 0 391 441 1 1
CDK5 STIP1 289 0 62 388 1 1
CDK5 TSSK1B 0 0 0 175 1 1
CDK5 NFAT5 0 0 108 281 1 1
CDK5 RBM8A 0 0 107 174 1 1
CDK5 CCNT2 0 0 134 220 1 1
CDK5 PPP1R2 213 0 134 386 1 1
CDK5 EEF2 0 0 134 168 1 2
CDK5 TTL 0 0 108 199 1 1
CDK5 FIS1 0 0 243 290 1 2
CDK5 RCAN1 0 0 165 165 1 2
CDK5 APH1B 0 0 108 300 1 1
CDK5 ATP13A2 0 0 134 166 1 1
CDK5 ABI2 0 0 231 301 1 1
CDK5 VCL 0 0 170 182 1 1
CDK5 SYN2 0 0 318 497 1 1
CDK5 ALDH7A1 0 0 156 155 1 1
CDK5 PEBP1 0 0 438 454 1 1
CDK5 COA8 0 0 194 306 1 1
CDK5 POLR1C 0 0 0 259 1 1
CDK5 MEF2C 0 0 208 241 1 1
CDK5 GSAP 0 0 150 170 1 1
CDK5 BDNF 61 600 651 867 1 2
CDK5 UNC13A 0 0 117 151 1 1
CDK5 NR4A2 0 0 171 177 1 1
CDK5 TRAP1 177 0 57 277 1 2
CDK5 HTR2C 0 0 112 180 1 1
CDK5 CASP2 0 0 150 203 1 1
CDK5 ECHDC2 0 0 49 168 1 1
CDK5 TNF 0 0 325 339 1 2
CDK5 SNAP25 0 0 324 350 1 1
CDK5 NBR1 0 0 48 250 1 2
CDK5 C1orf61 213 0 59 227 1 1
CDK5 DNAJC6 0 0 181 241 1 1
CDK5 STK32C 0 0 0 178 1 1
CDK5 SEMA4D 0 0 305 305 1 1
CDK5 ELP2 0 0 55 157 1 1
CDK5 TUBB4B 0 0 47 269 1 1
CDK5 C22orf29 0 0 171 171 1 1
CDK5 PAFAH1B1 0 0 824 917 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0005524 Molecular Function ATP binding enables IEA
GO:0005176 Molecular Function ErbB-2 class receptor binding enables ISS
GO:0043125 Molecular Function ErbB-3 class receptor binding enables ISS
GO:0051879 Molecular Function Hsp90 protein binding enables IEA
GO:0030549 Molecular Function acetylcholine receptor activator activity enables ISS
GO:0004693 Molecular Function cyclin-dependent protein serine/threonine kinase activity enables IBA
GO:0004693 Molecular Function cyclin-dependent protein serine/threonine kinase activity enables TAS
GO:0016301 Molecular Function kinase activity enables ISS
GO:0008017 Molecular Function microtubule binding NOT enables TAS
GO:0002039 Molecular Function p53 binding enables IEA
GO:0005515 Molecular Function protein binding enables IPI
GO:0004672 Molecular Function protein kinase activity enables TAS
GO:0106310 Molecular Function protein serine kinase activity enables IEA
GO:0004674 Molecular Function protein serine/threonine kinase activity enables IDA
GO:0004674 Molecular Function protein serine/threonine kinase activity enables ISS
GO:0004674 Molecular Function protein serine/threonine kinase activity enables NAS
GO:0004674 Molecular Function protein serine/threonine kinase activity enables TAS
GO:0048156 Molecular Function tau protein binding enables NAS
GO:0050321 Molecular Function tau-protein kinase activity enables ISS
GO:0050321 Molecular Function tau-protein kinase activity enables NAS
GO:0014044 Biological Process Schwann cell development involved_in IEA
GO:0048675 Biological Process axon extension involved_in TAS
GO:0007409 Biological Process axonogenesis involved_in IBA
GO:0048148 Biological Process behavioral response to cocaine involved_in IEA
GO:0070509 Biological Process calcium ion import involved_in IEA
GO:0051301 Biological Process cell division involved_in IEA
GO:0007160 Biological Process cell-matrix adhesion involved_in IEA
GO:1904646 Biological Process cellular response to amyloid-beta involved_in ISS
GO:0021954 Biological Process central nervous system neuron development involved_in IEA
GO:0021697 Biological Process cerebellar cortex formation involved_in IEA
GO:0007268 Biological Process chemical synaptic transmission involved_in TAS
GO:0022038 Biological Process corpus callosum development involved_in IEA
GO:0048813 Biological Process dendrite morphogenesis involved_in IEA
GO:0060079 Biological Process excitatory postsynaptic potential involved_in IEA
GO:0021766 Biological Process hippocampus development involved_in IEA
GO:0006886 Biological Process intracellular protein transport involved_in IEA
GO:0021819 Biological Process layer formation in cerebral cortex involved_in IEA
GO:0000226 Biological Process microtubule cytoskeleton organization involved_in TAS
GO:0008045 Biological Process motor neuron axon guidance involved_in IEA
GO:0045892 Biological Process negative regulation of DNA-templated transcription involved_in IMP
GO:0030517 Biological Process negative regulation of axon extension involved_in IEA
GO:0045786 Biological Process negative regulation of cell cycle involved_in IEA
GO:0046826 Biological Process negative regulation of protein export from nucleus involved_in IEA
GO:0031397 Biological Process negative regulation of protein ubiquitination involved_in IEA
GO:0045861 Biological Process negative regulation of proteolysis involved_in IMP
GO:0031914 Biological Process negative regulation of synaptic plasticity involved_in IEA
GO:0051402 Biological Process neuron apoptotic process involved_in IBA
GO:0051402 Biological Process neuron apoptotic process involved_in TAS
GO:0030182 Biological Process neuron differentiation involved_in ISS
GO:0030182 Biological Process neuron differentiation involved_in TAS
GO:0001764 Biological Process neuron migration involved_in TAS
GO:0031175 Biological Process neuron projection development involved_in ISS
GO:0031175 Biological Process neuron projection development involved_in TAS
GO:0048709 Biological Process oligodendrocyte differentiation involved_in IDA
GO:0018105 Biological Process peptidyl-serine phosphorylation involved_in IDA
GO:0018105 Biological Process peptidyl-serine phosphorylation involved_in ISS
GO:0018107 Biological Process peptidyl-threonine phosphorylation involved_in ISS
GO:0016310 Biological Process phosphorylation involved_in IDA
GO:0045956 Biological Process positive regulation of calcium ion-dependent exocytosis involved_in IEA
GO:0043525 Biological Process positive regulation of neuron apoptotic process involved_in ISS
GO:0090314 Biological Process positive regulation of protein targeting to membrane involved_in IEA
GO:0035418 Biological Process protein localization to synapse involved_in IEA
GO:0006468 Biological Process protein phosphorylation involved_in IBA
GO:0006468 Biological Process protein phosphorylation involved_in TAS
GO:0032801 Biological Process receptor catabolic process involved_in IEA
GO:0043113 Biological Process receptor clustering involved_in IEA
GO:0042981 Biological Process regulation of apoptotic process involved_in TAS
GO:0051726 Biological Process regulation of cell cycle involved_in TAS
GO:0030334 Biological Process regulation of cell migration involved_in IEA
GO:0061001 Biological Process regulation of dendritic spine morphogenesis involved_in ISS
GO:0016241 Biological Process regulation of macroautophagy involved_in TAS
GO:1903076 Biological Process regulation of protein localization to plasma membrane involved_in ISS
GO:0048167 Biological Process regulation of synaptic plasticity involved_in ISS
GO:0048167 Biological Process regulation of synaptic plasticity involved_in TAS
GO:0051966 Biological Process regulation of synaptic transmission, glutamatergic involved_in ISS
GO:1903421 Biological Process regulation of synaptic vesicle recycling involved_in NAS
GO:0048511 Biological Process rhythmic process involved_in IEA
GO:0019233 Biological Process sensory perception of pain involved_in IEA
GO:0007519 Biological Process skeletal muscle tissue development involved_in IEA
GO:0007416 Biological Process synapse assembly involved_in TAS
GO:0001963 Biological Process synaptic transmission, dopaminergic involved_in IEA
GO:0035249 Biological Process synaptic transmission, glutamatergic involved_in IEA
GO:0048488 Biological Process synaptic vesicle endocytosis involved_in TAS
GO:0016079 Biological Process synaptic vesicle exocytosis involved_in TAS
GO:0048489 Biological Process synaptic vesicle transport involved_in IBA
GO:0008542 Biological Process visual learning involved_in IEA
GO:0030424 Cellular Component axon located_in ISS
GO:0030054 Cellular Component cell junction located_in IDA
GO:0000307 Cellular Component cyclin-dependent protein kinase holoenzyme complex part_of IPI
GO:0000307 Cellular Component cyclin-dependent protein kinase holoenzyme complex part_of ISS
GO:0005737 Cellular Component cytoplasm is_active_in IBA
GO:0005737 Cellular Component cytoplasm located_in ISS
GO:0005829 Cellular Component cytosol located_in TAS
GO:0030425 Cellular Component dendrite located_in ISS
GO:0030175 Cellular Component filopodium located_in IEA
GO:0030426 Cellular Component growth cone located_in ISS
GO:0030027 Cellular Component lamellipodium located_in IEA
GO:0016020 Cellular Component membrane located_in ISS
GO:0005874 Cellular Component microtubule colocalizes_with ISS
GO:0031594 Cellular Component neuromuscular junction located_in ISS
GO:0043005 Cellular Component neuron projection located_in ISS
GO:0043025 Cellular Component neuronal cell body located_in ISS
GO:0005654 Cellular Component nucleoplasm located_in IDA
GO:0005654 Cellular Component nucleoplasm located_in TAS
GO:0005634 Cellular Component nucleus is_active_in IBA
GO:0005634 Cellular Component nucleus located_in ISS
GO:0043204 Cellular Component perikaryon located_in IEA
GO:0005886 Cellular Component plasma membrane located_in IDA
GO:0014069 Cellular Component postsynaptic density located_in ISS
GO:0098793 Cellular Component presynapse located_in IEA
GO:0016533 Cellular Component protein kinase 5 complex part_of IPI
GO:0016533 Cellular Component protein kinase 5 complex part_of ISS
Pathways
Name DB ID
Hemostasis Reactome R-HSA-109582
Opioid Signalling Reactome R-HSA-111885
Developmental Biology Reactome R-HSA-1266738
Signal Transduction Reactome R-HSA-162582
Disease Reactome R-HSA-1643685
Signaling by NTRKs Reactome R-HSA-166520
DARPP-32 events Reactome R-HSA-180024
Signaling by NTRK1 (TRKA) Reactome R-HSA-187037
Nuclear Events (kinase and transcription factor activation) Reactome R-HSA-198725
Generic Transcription Pathway Reactome R-HSA-212436
Transcriptional Regulation by TP53 Reactome R-HSA-3700989
Signaling by GPCR Reactome R-HSA-372790
Semaphorin interactions Reactome R-HSA-373755
GPCR downstream signalling Reactome R-HSA-388396
CRMPs in Sema3A signaling Reactome R-HSA-399956
G alpha (i) signalling events Reactome R-HSA-418594
Axon guidance Reactome R-HSA-422475
Regulation of TP53 Activity Reactome R-HSA-5633007
Regulation of TP53 Activity through Phosphorylation Reactome R-HSA-6804756
RNA Polymerase II Transcription Reactome R-HSA-73857
Gene expression (Transcription) Reactome R-HSA-74160
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models Reactome R-HSA-8862803
Neurodegenerative Diseases Reactome R-HSA-8863678
Signaling by NTRK2 (TRKB) Reactome R-HSA-9006115
Signaling by Receptor Tyrosine Kinases Reactome R-HSA-9006934
NGF-stimulated transcription Reactome R-HSA-9031628
Activated NTRK2 signals through CDK5 Reactome R-HSA-9032845
Transcriptional Regulation by NPAS4 Reactome R-HSA-9634815
Diseases of programmed cell death Reactome R-HSA-9645723
Nervous system development Reactome R-HSA-9675108
Defective Intrinsic Pathway for Apoptosis Reactome R-HSA-9734009
NPAS4 regulates expression of target genes Reactome R-HSA-9768919
Factors involved in megakaryocyte development and platelet production Reactome R-HSA-983231
DNA IR-double strand breaks and cellular response via ATM (WP3959) WikiPathways WP3959_r118468
Alzheimer's disease (WP5124) WikiPathways WP5124_r123917
Alzheimer's disease and miRNA effects (WP2059) WikiPathways WP2059_r119468
Neurogenesis regulation in the olfactory epithelium (WP5265) WikiPathways WP5265_r123524
Brain-derived neurotrophic factor (BDNF) signaling pathway (WP2380) WikiPathways WP2380_r120727
ATM signaling in development and disease (WP3878) WikiPathways WP3878_r123399
Nicotine effect on dopaminergic neurons (WP1602) WikiPathways WP1602_r117165
DNA damage response (WP707) WikiPathways WP707_r124174
miRNA regulation of DNA damage response (WP1530) WikiPathways WP1530_r124175
Transcripts
Accession Version MolecularType Name NCBI Comments
NM_001164410 3 mRNA transcript variant 2 NC_000007 Reference
NM_004935 4 mRNA transcript variant 1 NC_000007 Reference