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CGA

glycoprotein hormones, alpha polypeptide
General Information
Name glycoprotein hormones, alpha polypeptide
Alias
  • glycoprotein hormones alpha chain
  • FSH-alpha
  • LSH-alpha
  • TSH-alpha
  • anterior pituitary glycoprotein hormones common subunit alpha
  • choriogonadotropin alpha chain
  • chorionic gonadotrophin subunit alpha
  • chorionic gonadotropin, alpha polypeptide
  • follicle-stimulating hormone alpha chain
  • follicle-stimulating hormone alpha subunit
  • follitropin alpha chain
  • luteinizing hormone alpha chain
  • lutropin alpha chain
  • thyroid-stimulating hormone alpha chain
  • thyrotropin alpha chain
Gene_family Receptor ligands|Glycoprotein hormone subunits
organism Homo sapiens
entrez_id 1081
location 6q14.3
transcript_count 2
exon_count 5
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
    Stringdb Glycoprotein hormones, alpha polypeptide; Belongs to the glycoprotein hormones subunit alpha family
    nextProt Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
CGA BioGRID TRIO GeneID BioGRID Affinity Capture-MS
CGA BioGRID TRAPPC10 GeneID BioGRID Affinity Capture-MS
CGA BioGRID TRAPPC2 GeneID BioGRID Affinity Capture-MS
CGA BioGRID RNF166 GeneID BioGRID Affinity Capture-MS
CGA BioGRID OLFM2 GeneID BioGRID Affinity Capture-MS
CGA BioGRID TRAPPC9 GeneID BioGRID Affinity Capture-MS
CGA BioGRID ERO1B GeneID BioGRID Affinity Capture-MS
CGA BioGRID RNF114 GeneID BioGRID Affinity Capture-MS
CGA BioGRID RBM22 GeneID BioGRID Affinity Capture-MS
CGA BioGRID KLHL26 GeneID BioGRID Affinity Capture-MS
CGA BioGRID MTMR12 GeneID BioGRID Affinity Capture-MS
CGA BioGRID ERLEC1 GeneID BioGRID Affinity Capture-MS
CGA BioGRID EIF2AK3 GeneID BioGRID Affinity Capture-MS
CGA BioGRID PPT2 GeneID BioGRID Affinity Capture-MS
CGA BioGRID MTM1 GeneID BioGRID Affinity Capture-MS
CGA BioGRID SMAD2 GeneID BioGRID Affinity Capture-MS
CGA BioGRID LAMC1 GeneID BioGRID Affinity Capture-MS
CGA BioGRID FPGS GeneID BioGRID Affinity Capture-MS
CGA BioGRID FN1 GeneID BioGRID Affinity Capture-MS
CGA BioGRID BCKDHA GeneID BioGRID Affinity Capture-MS
CGA BioGRID ATP6V1G2 GeneID BioGRID Affinity Capture-MS
CGA BioGRID FSHR GeneID BioGRID Reconstituted Complex
CGA BioGRID PTPN12 GeneID BioGRID Two-hybrid
CGA Protein CGB5 GeneID HPRD
CGA Protein TSHB GeneID HPRD
CGA Protein PTPN12 GeneID HPRD
CGA Protein PTN GeneID HPRD
CGA Protein LHCGR GeneID HPRD
CGA Protein LHB GeneID HPRD
CGA Protein FSHB GeneID HPRD
CGA Protein CGB3 GeneID HPRD
CGA Protein CGA GeneID HPRD
CGA BioGRID CGB3 GeneID BioGRID Co-crystal Structure
CGA BioGRID LHCGR GeneID BioGRID Affinity Capture-Western
CGA BioGRID FSHB GeneID BioGRID Co-crystal Structure
CGA BioGRID PTN GeneID BioGRID Two-hybrid
StringDB
A B experiments database textmining combined score hadb nhadb
CGA JDP2 0 0 0 213 1 1
CGA GGTLC3 0 0 806 806 1 1
CGA HARS2 0 0 643 643 1 1
CGA POU4F2 0 0 54 309 1 1
CGA POU4F1 0 0 0 173 1 1
CGA TCF20 0 0 65 226 1 1
CGA S100A6 0 0 398 398 1 1
CGA PIK3C3 0 0 0 183 1 2
CGA GPHB5 0 500 0 499 1 1
CGA DDX21 0 0 460 471 1 1
CGA CCT3 0 0 205 259 1 1
CGA OXT 0 0 134 370 1 1
CGA EED 0 0 42 303 1 1
CGA NOTCH1 0 0 134 152 1 2
CGA LRBA 0 0 0 418 1 1
CGA C1QTNF4 0 0 95 187 1 1
CGA GCA 0 0 663 750 1 1
CGA GPHA2 0 500 0 552 1 1
CGA GPR101 0 0 101 255 1 1
CGA GDA 0 0 0 155 1 1
CGA EGR1 0 0 114 205 1 2
CGA NPVF 0 0 113 236 1 1
CGA DUXA 0 0 0 205 1 1
CGA HRAS 0 0 248 248 1 2
CGA DIO2 0 0 234 234 1 1
CGA CTNNB1 0 0 166 165 1 2
CGA HYAL1 0 0 0 297 1 1
CGA CD2 0 0 307 307 1 1
CGA APOC2 0 0 387 386 1 1
CGA FSHB 973 900 681 999 1 1
CGA SLC18A1 0 0 164 191 1 1
CGA ID1 0 0 49 151 1 1
CGA IL1B 0 0 66 160 1 2
CGA ENSG00000267335 0 0 0 378 1 1
CGA CHST8 0 900 0 900 1 1
CGA ISL1 0 0 81 164 1 1
CGA TRPM7 0 0 0 157 1 1
CGA MITF 0 0 53 153 1 2
CGA NF1 0 0 195 195 1 1
CGA HYAL2 0 0 0 303 1 1
CGA CSHL1 0 0 0 505 1 1
CGA RPLP2 0 0 0 217 1 1
CGA VIP 0 500 0 551 1 1
CGA ACACB 0 0 0 177 1 1
CGA GGCT 0 0 392 392 1 1
CGA ALOX5AP 0 0 213 213 1 1
CGA CYSLTR2 0 0 213 213 1 1
CGA APOA1 0 0 103 178 1 1
CGA GAPDH 0 0 261 261 1 2
CGA KCNA10 0 0 0 209 1 1
CGA LHX3 0 0 124 726 1 1
CGA AKT1 0 0 148 232 1 2
CGA ERVFRD-1 0 0 188 188 1 1
CGA GLYAT 0 0 113 355 1 1
CGA GGT1 0 0 764 764 1 1
CGA MMAA 0 0 126 314 1 1
CGA LHX2 0 0 134 236 1 1
CGA PTHLH 0 500 0 499 1 1
CGA CALY 0 0 150 173 1 1
CGA ADCYAP1 0 500 106 606 1 1
CGA CPE 0 0 112 158 1 1
CGA SLC25A20 0 0 103 303 1 1
CGA KISS1 0 0 150 184 1 1
CGA CD4 0 0 112 180 1 2
CGA GNRHR 0 0 468 803 1 1
CGA MGAM 0 0 0 179 1 1
CGA CFP 0 0 91 434 1 1
CGA NR5A2 0 0 0 195 1 1
CGA GSTA2 0 0 122 172 1 1
CGA TANC1 0 0 170 205 1 1
CGA PLD5 0 0 161 161 1 1
CGA PITX3 0 0 48 167 1 1
CGA GABRR1 0 0 720 720 1 1
CGA ERBB2 0 0 171 171 1 2
CGA GGT2 0 0 805 805 1 1
CGA OR4L1 0 0 112 167 1 1
CGA PCDHGA6 0 0 162 161 1 1
CGA POLE 0 0 174 173 1 1
CGA APOA2 0 0 0 152 1 1
CGA MAG 0 0 151 184 1 1
CGA DHRS2 0 0 0 151 1 1
CGA GUCA1A 0 0 369 369 1 1
CGA GATM 0 0 212 212 1 1
CGA GRIK4 0 0 0 189 1 1
CGA PEX6 0 0 134 316 1 1
CGA PFKFB3 0 0 54 152 1 2
CGA PMS2 0 0 56 153 1 1
CGA FGG 0 0 0 151 1 1
CGA BTC 0 0 486 485 1 1
CGA ODC1 0 0 0 179 1 1
CGA GTF3C3 0 0 59 227 1 1
CGA FZD2 0 0 0 219 1 1
CGA PITX1 0 0 67 301 1 1
CGA USP39 0 0 0 189 1 1
CGA NPY 0 0 103 357 1 1
CGA AREG 0 0 432 432 1 1
CGA PIP4K2A 0 0 76 153 1 1
CGA CDK5R2 0 0 0 263 1 1
CGA IGF1 0 0 75 243 1 2
CGA ANAPC2 0 0 329 329 1 1
CGA SHOX2 0 0 0 157 1 1
CGA MNX1 0 0 0 158 1 1
CGA FOXL2 0 0 144 399 1 1
CGA APOB 0 0 88 177 1 2
CGA GCM1 0 0 218 266 1 1
CGA MAP2K5 0 0 0 254 1 1
CGA AGT 0 0 0 254 1 1
CGA SPTSSB 0 0 0 167 1 1
CGA SCG5 0 0 297 297 1 1
CGA TFAP2A 0 900 0 902 1 1
CGA GCG 0 500 119 557 1 1
CGA GCDH 0 0 310 309 1 1
CGA CHGA 0 0 483 506 1 1
CGA INHBA 0 900 0 900 1 1
CGA ADM2 0 500 81 520 1 1
CGA PRLR 0 0 0 250 1 1
CGA PCP2 0 0 129 460 1 1
CGA GH1 0 0 46 508 1 1
CGA ACACA 0 0 259 458 1 1
CGA TCTA 0 0 248 295 1 1
CGA PIK3CA 0 0 283 282 1 2
CGA APOH 0 0 0 156 1 1
CGA NTS 0 0 0 351 1 1
CGA INSL3 0 500 0 534 1 1
CGA TFAP2C 0 900 0 900 1 1
CGA AMY2A 0 0 441 441 1 1
CGA SLC16A2 0 0 147 181 1 1
CGA GLS 0 0 502 502 1 2
CGA OFD1 0 0 0 284 1 2
CGA MSX1 0 0 307 307 1 1
CGA RAB3B 0 0 66 169 1 1
CGA EYA3 0 0 120 287 1 1
CGA GTF3C5 0 0 161 602 1 1
CGA RHAG 0 0 0 185 1 1
CGA CSH2 0 0 535 760 1 1
CGA LHX9 0 0 66 183 1 1
CGA BTBD9 0 0 0 190 1 1
CGA SDHC 0 0 189 204 1 1
CGA MC3R 0 0 139 191 1 1
CGA RXFP2 0 0 75 282 1 1
CGA DCT 0 0 0 157 1 1
CGA CGB1 0 0 630 760 1 1
CGA GTF3C4 0 0 46 292 1 1
CGA PCDHGA3 0 0 166 165 1 1
CGA IL15 0 0 0 208 1 1
CGA MYC 0 0 210 210 1 2
CGA KISS1R 0 0 0 303 1 1
CGA TSHR 0 500 140 579 1 1
CGA POU5F1B 0 0 0 204 1 1
CGA POU5F1 0 0 125 274 1 2
CGA GCAT 0 0 134 186 1 1
CGA IGSF1 0 0 0 220 1 1
CGA GIP 0 500 0 499 1 1
CGA TBX1 0 0 257 277 1 1
CGA NPFFR2 0 0 0 211 1 1
CGA GALR1 0 0 0 296 1 1
CGA CHGB 0 0 155 173 1 1
CGA NPFFR1 0 0 0 211 1 1
CGA GBA 0 0 385 384 1 1
CGA NT5DC3 0 0 182 181 1 1
CGA BUD13 0 0 181 181 1 1
CGA RPA1 0 0 72 168 1 1
CGA MLANA 0 0 123 187 1 1
CGA EMX2 0 0 74 174 1 1
CGA GH2 0 0 0 505 1 1
CGA POU1F1 0 0 218 786 1 1
CGA PSIP1 0 0 63 232 1 1
CGA GCM2 0 0 182 233 1 1
CGA TRH 0 0 243 540 1 1
CGA EMX1 0 0 49 150 1 1
CGA SKOR1 0 0 108 586 1 1
CGA FSHR 847 500 504 963 1 1
CGA SSTR4 0 0 0 156 1 1
CGA MEIS1 0 0 74 224 1 1
CGA NR5A1 0 0 150 431 1 1
CGA GABRR2 0 0 769 769 1 1
CGA CALCB 0 500 0 499 1 1
CGA STAR 0 0 0 163 1 1
CGA PITX2 0 0 0 160 1 1
CGA PGC 0 0 275 293 1 1
CGA EGFR 0 0 183 183 1 2
CGA SLC9C1 0 0 103 425 1 1
CGA SCG3 0 0 385 384 1 1
CGA SPAM1 0 0 0 303 1 1
CGA SHOX 0 0 97 207 1 1
CGA GAA 0 0 103 592 1 2
CGA HMBS 0 0 81 204 1 1
CGA LHB 213 800 616 957 1 1
CGA PEX26 0 0 92 294 1 1
CGA MDM2 0 0 131 150 1 2
CGA TP53 0 0 294 294 1 2
CGA LEPROT 0 0 122 592 1 1
CGA CCRN4L 0 0 0 189 1 1
CGA IAPP 0 500 108 583 1 2
CGA MPG 0 0 228 227 1 2
CGA SKOR2 0 0 0 359 1 1
CGA PAX6 0 0 82 154 1 1
CGA FETUB 0 0 465 465 1 1
CGA GDF5 0 0 0 403 1 1
CGA AVP 0 500 0 540 1 1
CGA CSH1 0 0 431 706 1 1
CGA GTF3C2 0 0 42 289 1 1
CGA MAF 0 0 166 165 1 1
CGA LGALS4 0 0 150 172 1 1
CGA NODAL 0 0 321 321 1 1
CGA EREG 0 0 398 398 1 1
CGA CBLN2 0 0 0 390 1 1
CGA DRD2 0 0 46 163 1 1
CGA SCG2 0 0 150 190 1 1
CGA TRHR 0 0 294 320 1 1
CGA BMP7 0 0 0 214 1 1
CGA FCF1 0 0 44 292 1 1
CGA LOC93432 0 0 0 179 1 1
CGA NPTX1 0 0 0 153 1 1
CGA LHCGR 270 500 218 717 1 1
CGA AGRP 0 0 107 206 1 1
CGA ACTC1 0 0 141 151 1 1
CGA LEP 0 0 74 230 1 1
CGA OPRL1 0 0 0 189 1 1
CGA SCT 0 500 0 513 1 1
CGA AMBP 0 0 47 168 1 1
CGA AVPR1B 0 0 75 547 1 1
CGA CLPB 0 0 66 162 1 1
CGA GABRQ 0 0 0 258 1 1
CGA ZC3H12A 0 0 0 190 1 1
CGA CDX2 0 0 179 179 1 1
CGA ANKRD55 0 0 0 239 1 1
CGA POU4F3 0 0 0 173 1 1
CGA RFX6 0 0 0 512 1 1
CGA GSG1L 0 0 46 163 1 1
CGA ATP1A4 0 0 438 438 1 1
CGA NBEAL2 0 0 0 190 1 1
CGA NBEAL1 0 0 0 190 1 1
CGA PTEN 0 0 193 193 1 2
CGA ACSL4 0 0 48 197 1 1
CGA RFX4 0 0 0 167 1 1
CGA ALB 0 0 150 223 1 2
CGA DNAAF2 0 0 0 302 1 1
CGA AP4B1 0 0 0 302 1 1
CGA HESX1 0 0 0 318 1 1
CGA CRH 0 500 0 698 1 1
CGA SYP 0 0 204 204 1 1
CGA GNAS 0 0 95 151 1 1
CGA INHA 0 900 0 902 1 1
CGA TACR3 0 0 0 216 1 1
CGA KCNH8 0 0 0 154 1 1
CGA TYR 0 0 46 248 1 2
CGA PROCR 0 0 391 390 1 1
CGA GTF3C6 0 0 67 235 1 1
CGA PIK3R1 0 0 139 192 1 1
CGA CRHR1 0 0 0 161 1 1
CGA GHRHR 0 0 204 637 1 1
CGA GGACT 0 0 252 252 1 1
CGA PMEL 0 0 0 151 1 1
CGA TBX19 0 0 134 732 1 1
CGA EOMES 0 0 108 172 1 1
CGA DOCK11 0 0 265 335 1 1
CGA IGFBP1 0 0 0 213 1 1
CGA PRL 0 0 155 640 1 1
CGA CRABP1 0 0 0 226 1 1
CGA ESR1 0 0 171 209 1 2
CGA PSG3 0 0 212 212 1 1
CGA B3GALT2 0 0 128 158 1 1
CGA POMC 0 500 241 916 1 1
CGA SEZ6L2 0 0 74 224 1 1
CGA GATA2 0 0 127 279 1 1
CGA PCDHB8 0 0 134 153 1 1
CGA NANOG 0 0 75 171 1 2
CGA TCEAL5 0 0 192 192 1 1
CGA GUCY2C 0 0 242 241 1 1
CGA ENO2 0 0 193 193 1 1
CGA CALCA 0 500 79 527 1 1
CGA GALP 0 0 0 175 1 1
CGA GCLC 0 0 141 194 1 1
CGA PTH2 0 500 0 499 1 1
CGA NPS 0 500 0 499 1 1
CGA PMS1 0 0 0 302 1 1
CGA SSTR1 0 0 0 160 1 1
CGA BPIFB6 0 0 0 511 1 1
CGA TERT 0 0 157 249 1 2
CGA APBB3 0 0 0 186 1 1
CGA SEC14L3 0 0 150 171 1 1
CGA DPPA4 0 0 0 151 1 1
CGA ARID1A 0 0 181 181 1 1
CGA INHBC 0 900 0 900 1 1
CGA HBZ 0 0 0 164 1 1
CGA EIF2A 0 0 113 168 1 2
CGA ARHGEF16 0 0 0 205 1 1
CGA TRPM6 0 0 0 157 1 1
CGA TTC3 0 0 218 227 1 1
CGA INHBB 0 900 57 901 1 1
CGA FST 0 0 103 246 1 1
CGA SSTR5 0 0 95 253 1 1
CGA GHRH 0 500 141 734 1 1
CGA RPL4 0 0 74 216 1 1
CGA CYSLTR1 0 0 261 261 1 1
CGA S100A8 0 0 260 260 1 2
CGA FOS 0 0 90 152 1 2
CGA GHSR 0 0 0 189 1 1
CGA THRB 0 0 150 169 1 1
CGA TNC 0 0 536 536 1 1
CGA ZNF800 0 0 95 292 1 1
CGA SSTR3 0 0 60 221 1 1
CGA LHX4 0 0 92 605 1 1
CGA PTH 0 500 81 520 1 1
CGA ETV1 0 0 48 167 1 1
CGA KRAS 0 0 166 165 1 2
CGA NDUFB2 0 0 468 479 1 1
CGA TSHB 213 800 601 976 1 1
CGA DCC 0 0 74 215 1 1
CGA NRAS 0 0 388 388 1 1
CGA LTC4S 0 0 286 286 1 1
CGA PROP1 0 0 81 433 1 1
CGA ADCY10 0 0 181 181 1 1
CGA CGB2 0 0 0 378 1 1
CGA SEZ6L 0 0 0 197 1 1
CGA LEPROTL1 0 0 0 261 1 1
CGA SERPINA7 0 0 0 153 1 1
CGA VMO1 0 0 145 159 1 1
CGA CYP11A1 0 0 95 189 1 1
CGA CGB 927 0 517 976 1 1
CGA DSCR8 0 0 0 161 1 1
CGA TMEM130 0 0 143 174 1 1
CGA CDK5R1 0 0 0 269 1 1
CGA TAPBP 0 0 92 154 1 1
CGA SI 0 0 0 179 1 1
CGA CYP19A1 0 0 86 183 1 2
CGA TRIO 0 0 218 218 1 1
CGA AMY2B 0 0 500 499 1 1
CGA PCCA 0 0 90 185 1 1
CGA ATP1A1 0 0 440 440 1 1
CGA NEUROD1 0 0 0 297 1 1
CGA CFC1 0 0 304 304 1 1
CGA SLC25A16 0 0 288 288 1 1
CGA KCNH4 0 0 0 154 1 1
CGA PKNOX2 0 0 147 157 1 1
CGA AFP 0 0 82 216 1 2
CGA SSTR2 0 0 142 596 1 1
CGA ACSM3 0 0 94 153 1 1
CGA NBEA 0 0 0 256 1 1
CGA HCRT 0 0 46 163 1 1
CGA DMBX1 0 0 128 422 1 1
CGA MRPS10 0 0 52 310 1 1
CGA FAR1 0 0 0 199 1 1
CGA INHBE 0 900 0 900 1 1
CGA KMT2C 0 0 164 163 1 1
CGA CRYM 0 0 0 293 1 1
CGA DNAH11 0 0 74 155 1 1
CGA NRSN1 0 0 134 332 1 1
CGA HARS 0 0 643 643 1 1
CGA SLC16A1 0 0 0 261 1 1
CGA ACTB 0 0 282 285 1 2
CGA INS 0 0 162 161 1 2
CGA KCNH3 0 0 0 154 1 1
CGA SLC7A3 0 0 167 187 1 1
CGA ALOX5 0 0 235 235 1 1
CGA BAIAP2 0 0 0 293 1 1
CGA CGB7 784 0 469 922 1 1
CGA S100A12 0 0 284 289 1 1
CGA CARTPT 0 0 84 184 1 1
CGA MEIOB 0 0 0 198 1 1
CGA RLN3 0 500 0 499 1 1
CGA KRT7 0 0 166 165 1 1
CGA TTR 0 0 102 299 1 1
CGA CRYGD 0 0 298 298 1 1
CGA GNRH1 0 0 395 562 1 1
CGA ADM 0 500 0 499 1 2
CGA CGB8 800 0 503 932 1 1
CGA INSR 0 0 270 270 1 1
CGA CDKN2A 0 0 214 231 1 2
CGA SST 0 0 108 399 1 1
CGA RLN2 0 500 0 499 1 1
CGA CGB5 944 0 0 963 1 1
CGA PBX1 0 0 67 201 1 1
CGA AHSG 0 0 0 158 1 1
CGA PEPD 0 0 398 398 1 1
CGA PDIA4 0 0 0 161 1 1
CGA GHR 0 0 55 160 1 1
CGA GDF3 0 0 0 154 1 1
CGA HBE1 0 0 0 273 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0016913 Molecular Function follicle-stimulating hormone activity enables IBA
GO:0016913 Molecular Function follicle-stimulating hormone activity enables IDA
GO:0005179 Molecular Function hormone activity enables IMP
GO:0005515 Molecular Function protein binding enables IPI
GO:0007186 Biological Process G protein-coupled receptor signaling pathway involved_in IDA
GO:0046884 Biological Process follicle-stimulating hormone secretion involved_in IEA
GO:0042699 Biological Process follicle-stimulating hormone signaling pathway involved_in NAS
GO:0009755 Biological Process hormone-mediated signaling pathway involved_in NAS
GO:0032275 Biological Process luteinizing hormone secretion involved_in IEA
GO:0046621 Biological Process negative regulation of organ growth involved_in IEA
GO:0035265 Biological Process organ growth involved_in IEA
GO:0030335 Biological Process positive regulation of cell migration involved_in NAS
GO:0008284 Biological Process positive regulation of cell population proliferation involved_in NAS
GO:0010893 Biological Process positive regulation of steroid biosynthetic process involved_in IBA
GO:0010893 Biological Process positive regulation of steroid biosynthetic process involved_in IDA
GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II involved_in NAS
GO:0010469 Biological Process regulation of signaling receptor activity involved_in IDA
GO:0030878 Biological Process thyroid gland development involved_in IEA
GO:0006590 Biological Process thyroid hormone generation involved_in IBA
GO:0005796 Cellular Component Golgi lumen located_in TAS
GO:0005576 Cellular Component extracellular region located_in TAS
GO:0005615 Cellular Component extracellular space is_active_in IBA
GO:0005615 Cellular Component extracellular space located_in IDA
GO:0016914 Cellular Component follicle-stimulating hormone complex part_of IBA
GO:0016914 Cellular Component follicle-stimulating hormone complex part_of IDA
GO:0016914 Cellular Component follicle-stimulating hormone complex part_of IPI
GO:0061696 Cellular Component pituitary gonadotropin complex part_of IPI
GO:0061696 Cellular Component pituitary gonadotropin complex part_of NAS
Pathways
Name DB ID
Metabolism Reactome R-HSA-1430728
Signal Transduction Reactome R-HSA-162582
Androgen biosynthesis Reactome R-HSA-193048
Mineralocorticoid biosynthesis Reactome R-HSA-193993
Metabolism of steroid hormones Reactome R-HSA-196071
Metabolism of amine-derived hormones Reactome R-HSA-209776
Glycoprotein hormones Reactome R-HSA-209822
Peptide hormone biosynthesis Reactome R-HSA-209952
Thyroxine biosynthesis Reactome R-HSA-209968
Generic Transcription Pathway Reactome R-HSA-212436
Peptide hormone metabolism Reactome R-HSA-2980736
Signaling by GPCR Reactome R-HSA-372790
Class A/1 (Rhodopsin-like receptors) Reactome R-HSA-373076
Hormone ligand-binding receptors Reactome R-HSA-375281
GPCR downstream signalling Reactome R-HSA-388396
Metabolism of proteins Reactome R-HSA-392499
G alpha (s) signalling events Reactome R-HSA-418555
Asparagine N-linked glycosylation Reactome R-HSA-446203
GPCR ligand binding Reactome R-HSA-500792
Metabolism of lipids Reactome R-HSA-556833
Post-translational protein modification Reactome R-HSA-597592
Metabolism of amino acids and derivatives Reactome R-HSA-71291
RNA Polymerase II Transcription Reactome R-HSA-73857
Gene expression (Transcription) Reactome R-HSA-74160
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors Reactome R-HSA-8864260
TFAP2 (AP-2) family regulates transcription of growth factors and their receptors Reactome R-HSA-8866910
Metabolism of steroids Reactome R-HSA-8957322
Transport to the Golgi and subsequent modification Reactome R-HSA-948021
N-glycan antennae elongation in the medial/trans-Golgi Reactome R-HSA-975576
Reactions specific to the complex N-glycan synthesis pathway Reactome R-HSA-975578
Thyroid stimulating hormone (TSH) signaling pathway (WP2032) WikiPathways WP2032_r122774
Prader-Willi and Angelman syndrome (WP3998) WikiPathways WP3998_r123316
Follicle stimulating hormone (FSH) signaling pathway (WP2035) WikiPathways WP2035_r120721
Thyroxine (thyroid hormone) production (WP1981) WikiPathways WP1981_r122822
Transcripts
Accession Version MolecularType Name NCBI Comments
NM_000735 4 mRNA transcript variant 2 NC_000006 Reference
NM_001252383 2 mRNA transcript variant 1 NC_000006 Reference