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RIPK3

receptor interacting serine/threonine kinase 3
General Information
Name receptor interacting serine/threonine kinase 3
Alias
  • receptor-interacting serine/threonine-protein kinase 3
  • RIP-3
  • RIP-like protein kinase 3
  • receptor interacting protein 3
Gene_family
organism Homo sapiens
entrez_id 11035
location 14q12
transcript_count 1
exon_count 10
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. [provided by RefSeq, Jul 2008]
    Stringdb Receptor-interacting serine/threonine-protein kinase 3; Essential for necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 and MLKL to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes may eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production
    nextProt (Microbial infection) In case of herpes simplex virus 1/HHV-1 infection, forms heteromeric amyloid structures with HHV-1 protein RIR1/ICP6 which may inhibit RIPK3-mediated necroptosis, thereby preventing host cell death pathway and allowing viral evasion.
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
RIPK3 BioGRID ZBP1 GeneID BioGRID Affinity Capture-Western
RIPK3 BioGRID ORF3a GeneID BioGRID Affinity Capture-Western; Co-localization
RIPK3 BioGRID LAMP1 GeneID BioGRID Co-localization
RIPK3 BioGRID TRIM34 GeneID BioGRID Affinity Capture-Western
RIPK3 BioGRID MLKL GeneID BioGRID Affinity Capture-Western
RIPK3 BioGRID TRIM28 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
RIPK3 BioGRID RIPK1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-localization; PCA; Two-hybrid
RIPK3 BioGRID TRIM25 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity
RIPK3 BioGRID LRATD2 GeneID BioGRID Affinity Capture-MS
RIPK3 BioGRID TCP11L1 GeneID BioGRID Affinity Capture-MS
RIPK3 BioGRID RLIM GeneID BioGRID Affinity Capture-MS
RIPK3 BioGRID ARFGEF1 GeneID BioGRID Affinity Capture-MS
RIPK3 BioGRID SLC1A1 GeneID BioGRID Affinity Capture-MS
RIPK3 BioGRID PCCA GeneID BioGRID Affinity Capture-MS
RIPK3 BioGRID GGT7 GeneID BioGRID Affinity Capture-MS
RIPK3 BioGRID EPHA4 GeneID BioGRID Affinity Capture-MS
RIPK3 BioGRID AMY1C GeneID BioGRID Affinity Capture-MS
RIPK3 BioGRID ZNG1C GeneID BioGRID Affinity Capture-MS
RIPK3 BioGRID TNF GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
RIPK3 BioGRID PRKN GeneID BioGRID Affinity Capture-Western; Co-localization
RIPK3 BioGRID FADD GeneID BioGRID Affinity Capture-Western
RIPK3 BioGRID CASP8 GeneID BioGRID Affinity Capture-Western
RIPK3 BioGRID HELQ GeneID BioGRID Reconstituted Complex
RIPK3 BioGRID TMEM44 GeneID BioGRID Reconstituted Complex
RIPK3 BioGRID TLE6 GeneID BioGRID Reconstituted Complex
RIPK3 BioGRID HSPBAP1 GeneID BioGRID Reconstituted Complex
RIPK3 BioGRID PELI1 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
RIPK3 BioGRID NME8 GeneID BioGRID Reconstituted Complex
RIPK3 BioGRID UTP11 GeneID BioGRID Reconstituted Complex
RIPK3 BioGRID IL24 GeneID BioGRID Reconstituted Complex
RIPK3 BioGRID ZSCAN20 GeneID BioGRID Reconstituted Complex
RIPK3 BioGRID H1-5 GeneID BioGRID Reconstituted Complex
RIPK3 BioGRID GBE1 GeneID BioGRID Reconstituted Complex
RIPK3 BioGRID BUB1B GeneID BioGRID Reconstituted Complex
RIPK3 BioGRID LMP-1 GeneID BioGRID Affinity Capture-Western; Co-localization
RIPK3 BioGRID RIPK3 GeneID BioGRID Biochemical Activity
RIPK3 BioGRID SRPK2 GeneID BioGRID Biochemical Activity
RIPK3 BioGRID ZG16B GeneID BioGRID Affinity Capture-MS
RIPK3 BioGRID PTPRK GeneID BioGRID Affinity Capture-MS
RIPK3 BioGRID DAXX GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
RIPK3 BioGRID BMH1 GeneID BioGRID Reconstituted Complex
RIPK3 BioGRID RFX6 GeneID BioGRID Two-hybrid
RIPK3 BioGRID INPP5K GeneID BioGRID Affinity Capture-MS
RIPK3 BioGRID CDC37 GeneID BioGRID Affinity Capture-MS
RIPK3 BioGRID STIP1 GeneID BioGRID Affinity Capture-MS
RIPK3 BioGRID PYGL GeneID BioGRID Affinity Capture-MS
RIPK3 BioGRID FKBP5 GeneID BioGRID Affinity Capture-MS
RIPK3 BioGRID FKBP4 GeneID BioGRID Affinity Capture-MS
RIPK3 BioGRID CTNND1 GeneID BioGRID Affinity Capture-MS
RIPK3 BioGRID XIAP GeneID BioGRID Reconstituted Complex
RIPK3 BioGRID BIRC3 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
RIPK3 BioGRID BIRC2 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
RIPK3 Protein TICAM1 GeneID HPRD
RIPK3 Protein RIPK1 GeneID HPRD
RIPK3 Protein TRAF2 GeneID HPRD
RIPK3 Protein TNFRSF1A GeneID HPRD
RIPK3 BioGRID TRAF2 GeneID BioGRID Affinity Capture-Western
RIPK3 BioGRID TNFRSF1A GeneID BioGRID Affinity Capture-Western
RIPK3 BioGRID TICAM1 GeneID BioGRID Affinity Capture-Western
StringDB
A B experiments database textmining combined score hadb nhadb
RIPK3 IFNGR1 0 0 66 160 1 1
RIPK3 CDK9 0 0 134 161 1 1
RIPK3 ARMC6 0 0 123 195 1 1
RIPK3 ASB2 0 0 0 159 1 1
RIPK3 FOXO1 0 0 91 163 1 2
RIPK3 FCRL6 0 0 0 154 1 1
RIPK3 BTRC 0 0 76 158 1 1
RIPK3 MYO3B 0 0 0 156 1 1
RIPK3 CAMK4 0 0 0 150 1 1
RIPK3 CASP14 0 0 123 161 1 1
RIPK3 HSPA5 106 0 170 334 1 2
RIPK3 FCER1A 0 0 0 195 1 1
RIPK3 PTPN11 0 0 68 154 1 1
RIPK3 IRAK3 0 0 112 176 1 1
RIPK3 GAB1 0 0 0 296 1 1
RIPK3 IRG1 0 0 181 198 1 1
RIPK3 LMO2 0 0 0 153 1 1
RIPK3 GNGT2 0 0 0 159 1 1
RIPK3 PSME2 0 0 112 152 1 1
RIPK3 FOS 0 0 134 160 1 2
RIPK3 YWHAZ 0 0 66 208 1 1
RIPK3 S100A8 0 0 0 183 1 2
RIPK3 PPM1N 0 0 0 198 1 1
RIPK3 MALRD1 0 0 0 190 1 1
RIPK3 GRID2 0 0 0 150 1 2
RIPK3 GNAI3 100 0 54 238 1 2
RIPK3 NOD1 0 0 243 274 1 2
RIPK3 UGP2 0 0 0 162 1 1
RIPK3 CLIC1 0 0 0 150 1 1
RIPK3 SHARPIN 0 0 560 577 1 1
RIPK3 WAS 0 0 0 236 1 1
RIPK3 CD86 0 0 142 302 1 1
RIPK3 LRRK2 0 0 149 264 1 2
RIPK3 GNAO1 0 0 0 177 1 1
RIPK3 MET 0 0 0 181 1 2
RIPK3 TRAF3 0 0 269 333 1 2
RIPK3 ANKRD45 0 0 0 175 1 1
RIPK3 PRKCH 0 0 0 163 1 1
RIPK3 PIM3 0 0 0 217 1 1
RIPK3 PMAIP1 0 0 241 257 1 2
RIPK3 TLR2 0 0 325 439 1 2
RIPK3 NFAM1 0 0 0 153 1 1
RIPK3 EIF4EBP2 0 0 0 278 1 1
RIPK3 OTUD7B 0 0 186 211 1 1
RIPK3 PNPLA8 0 0 0 163 1 1
RIPK3 ENTHD1 0 0 125 162 1 1
RIPK3 CD28 0 0 150 192 1 1
RIPK3 ATG12 0 0 234 248 1 2
RIPK3 ALOX5 0 0 74 247 1 1
RIPK3 ETV7 0 0 59 207 1 1
RIPK3 RAB4B 0 0 57 154 1 1
RIPK3 PSMB9 0 0 75 162 1 1
RIPK3 TNFRSF21 0 0 261 261 1 1
RIPK3 DAXX 270 0 95 372 1 1
RIPK3 GPA33 0 0 0 151 1 1
RIPK3 GNA15 0 0 48 251 1 1
RIPK3 PLEKHM1 0 0 92 162 1 1
RIPK3 LNX1 0 0 0 200 1 1
RIPK3 RPS6KC1 0 0 83 239 1 1
RIPK3 TRIB3 0 0 0 162 1 2
RIPK3 CXCL1 0 0 287 322 1 2
RIPK3 IL33 0 0 282 282 1 2
RIPK3 EGFLAM 0 0 56 169 1 1
RIPK3 CSF1 0 0 150 200 1 1
RIPK3 YWHAH 0 0 0 165 1 1
RIPK3 PHB2 0 0 194 223 1 1
RIPK3 PI4KA 0 0 0 157 1 1
RIPK3 HCK 0 0 0 227 1 1
RIPK3 S100A12 0 0 0 151 1 1
RIPK3 KLF2 0 0 0 174 1 1
RIPK3 CUL3 0 0 124 201 1 2
RIPK3 CHUK 0 900 391 915 1 1
RIPK3 WNT2 0 0 0 172 1 1
RIPK3 ITGAX 0 0 209 322 1 1
RIPK3 SLC11A1 0 0 0 212 1 1
RIPK3 SFN 0 0 0 165 1 2
RIPK3 EHBP1L1 0 0 0 167 1 1
RIPK3 CASP4 0 0 181 348 1 2
RIPK3 PLEKHG4B 0 0 0 184 1 1
RIPK3 ADPRH 0 0 0 151 1 1
RIPK3 TUBGCP2 0 0 0 157 1 1
RIPK3 NYNRIN 0 0 82 329 1 1
RIPK3 CTSD 0 0 181 237 1 2
RIPK3 AIF1L 105 0 0 162 1 1
RIPK3 ENSG00000267261 0 0 0 178 1 1
RIPK3 GNAI1 0 0 0 177 1 1
RIPK3 ACTG1 106 0 73 217 1 1
RIPK3 CMPK2 0 0 0 178 1 1
RIPK3 IKZF1 0 0 0 187 1 1
RIPK3 ATG7 0 0 390 425 1 2
RIPK3 TRAT1 0 0 112 155 1 1
RIPK3 CXCL2 0 0 154 193 1 1
RIPK3 PARVG 0 0 0 255 1 1
RIPK3 EFNB2 0 0 0 168 1 1
RIPK3 FMN1 0 0 0 175 1 1
RIPK3 GRK6 0 0 67 151 1 1
RIPK3 GFAP 0 0 150 230 1 2
RIPK3 PTEN 0 0 155 222 1 2
RIPK3 NEK7 0 0 165 174 1 1
RIPK3 STX11 0 0 0 216 1 1
RIPK3 STXBP5L 0 0 0 158 1 1
RIPK3 MAPK7 0 0 0 163 1 1
RIPK3 PRKAA2 0 0 0 247 1 2
RIPK3 VILL 0 0 0 225 1 1
RIPK3 FCER1G 0 0 0 166 1 1
RIPK3 RPS6KL1 0 0 0 155 1 1
RIPK3 SLC7A7 0 0 0 171 1 1
RIPK3 DNM1L 0 800 425 883 1 2
RIPK3 CASP5 0 0 287 479 1 1
RIPK3 TRAF7 0 0 108 231 1 1
RIPK3 PDZD3 0 0 0 169 1 1
RIPK3 RHOT2 0 0 45 163 1 1
RIPK3 SYK 0 0 167 217 1 2
RIPK3 NFKBIA 0 650 391 803 1 2
RIPK3 CLIC4 0 0 0 150 1 1
RIPK3 FHL1 0 0 94 168 1 1
RIPK3 ZC3H12A 0 0 72 163 1 1
RIPK3 ATAD2B 0 0 0 170 1 1
RIPK3 UBA52 0 900 0 901 1 1
RIPK3 MAPK10 0 0 88 230 1 2
RIPK3 ZP4 0 0 169 169 1 1
RIPK3 MEOX2 0 0 64 291 1 1
RIPK3 MAPK14 0 0 96 181 1 2
RIPK3 STK33 0 0 67 177 1 1
RIPK3 CSF3R 0 0 49 161 1 1
RIPK3 MCL1 0 0 295 321 1 2
RIPK3 ELF4 0 0 0 160 1 1
RIPK3 GMIP 0 0 0 160 1 1
RIPK3 CST7 0 0 0 207 1 1
RIPK3 DPM1 0 0 0 153 1 1
RIPK3 SPI1 0 0 74 363 1 1
RIPK3 NOX1 0 0 120 172 1 1
RIPK3 CTSB 0 0 211 241 1 2
RIPK3 MAPK6 0 0 0 164 1 1
RIPK3 IRF5 0 0 67 171 1 1
RIPK3 HMGB1 0 0 469 484 1 2
RIPK3 RAC1 0 0 0 153 1 2
RIPK3 PDIK1L 0 0 0 162 1 1
RIPK3 HOXB8 0 0 126 182 1 1
RIPK3 GNA11 0 0 63 178 1 1
RIPK3 RGS1 0 0 0 232 1 1
RIPK3 ITGAM 0 0 283 433 1 1
RIPK3 MAP3K5 0 0 293 284 1 1
RIPK3 TLR8 0 0 108 362 1 1
RIPK3 CAMK2G 0 0 86 159 1 1
RIPK3 WNT3A 0 0 66 178 1 2
RIPK3 LAPTM5 0 0 0 325 1 1
RIPK3 MAP2K6 0 0 0 158 1 1
RIPK3 ATG5 0 0 528 538 1 2
RIPK3 SASH3 0 0 0 326 1 1
RIPK3 TSPAN32 0 0 0 175 1 1
RIPK3 GBE1 270 0 0 297 1 1
RIPK3 STAT2 0 0 90 213 1 1
RIPK3 CEACAM4 0 0 0 214 1 1
RIPK3 ANO6 0 0 148 165 1 1
RIPK3 CMA1 0 0 66 189 1 1
RIPK3 HLA-F 0 0 0 152 1 1
RIPK3 ATG10 0 0 133 172 1 2
RIPK3 NFKBIB 0 650 53 682 1 1
RIPK3 AQP9 0 0 0 196 1 1
RIPK3 DFFB 0 0 220 220 1 1
RIPK3 MYO1F 0 0 0 173 1 1
RIPK3 MAMDC4 0 0 0 190 1 1
RIPK3 ISG15 0 0 90 164 1 2
RIPK3 WDFY4 0 0 0 382 1 1
RIPK3 TBX21 0 0 0 175 1 1
RIPK3 NEK2 0 0 0 212 1 1
RIPK3 MAP3K12 0 0 650 356 1 1
RIPK3 RPS6KA1 0 0 0 167 1 1
RIPK3 LILRB3 0 0 0 154 1 1
RIPK3 RABL3 0 0 0 189 1 1
RIPK3 SH3BP5L 0 0 103 161 1 1
RIPK3 IKBKG 0 900 521 952 1 1
RIPK3 CCR7 0 0 61 198 1 1
RIPK3 PARD6B 0 0 0 189 1 1
RIPK3 TNFAIP6 0 0 0 151 1 1
RIPK3 IFNAR1 0 0 448 482 1 1
RIPK3 PPTC7 0 0 0 198 1 1
RIPK3 CMKLR1 0 0 0 152 1 1
RIPK3 IREB2 0 0 194 229 1 1
RIPK3 BCAP31 0 0 134 152 1 1
RIPK3 RELB 0 0 243 287 1 2
RIPK3 BCL2A1 0 0 108 253 1 1
RIPK3 CDK17 0 0 0 165 1 1
RIPK3 TYMP 0 0 0 176 1 1
RIPK3 CCT2 98 0 0 209 1 1
RIPK3 GBP5 0 0 60 168 1 1
RIPK3 MAPK1 0 0 102 253 1 2
RIPK3 CSF1R 0 0 88 251 1 1
RIPK3 EFNA3 0 0 0 182 1 1
RIPK3 SLAMF8 0 0 0 179 1 1
RIPK3 SOCS1 0 0 125 221 1 1
RIPK3 BTK 0 0 64 192 1 1
RIPK3 SDK2 0 0 0 171 1 1
RIPK3 TANK 0 0 162 214 1 2
RIPK3 HLA-DMA 0 0 0 168 1 1
RIPK3 TIRAP 0 0 308 319 1 1
RIPK3 CD44 0 0 141 198 1 2
RIPK3 CASP2 0 0 390 403 1 1
RIPK3 GNAI2 0 0 0 198 1 1
RIPK3 TMEM71 0 0 0 155 1 1
RIPK3 ATP11C 0 0 152 187 1 1
RIPK3 CD300LF 0 0 0 299 1 1
RIPK3 ABI2 0 0 0 150 1 1
RIPK3 TBC1D10C 0 0 0 253 1 1
RIPK3 TSSK1B 0 0 0 226 1 1
RIPK3 APOBR 0 0 0 299 1 1
RIPK3 LPCAT3 0 0 163 187 1 1
RIPK3 DFFA 0 0 142 157 1 1
RIPK3 UAP1 0 0 0 169 1 1
RIPK3 EFNA1 0 0 0 168 1 1
RIPK3 RHEB 0 0 49 150 1 2
RIPK3 EVL 0 0 0 158 1 1
RIPK3 PHLPP2 0 0 0 162 1 1
RIPK3 MAP2K2 0 0 0 185 1 1
RIPK3 TXN 0 0 134 185 1 1
RIPK3 LCP1 0 0 0 209 1 1
RIPK3 INADL 0 0 0 159 1 1
RIPK3 GRIK5 0 0 0 150 1 1
RIPK3 PECAM1 0 0 103 201 1 1
RIPK3 UBB 0 900 0 906 1 1
RIPK3 TSSK2 0 0 0 227 1 1
RIPK3 CENPK 0 0 0 157 1 1
RIPK3 LY6D 0 0 95 251 1 1
RIPK3 YWHAQ 0 0 0 171 1 1
RIPK3 PPP2CA 0 0 0 151 1 1
RIPK3 PRKDC 106 0 0 191 1 2
RIPK3 IPMK 0 0 161 177 1 1
RIPK3 IFT43 0 0 188 188 1 1
RIPK3 SPNS3 0 0 0 222 1 1
RIPK3 PIK3C2B 0 0 74 159 1 1
RIPK3 PTAFR 0 0 46 170 1 1
RIPK3 GRAMD4 0 0 181 213 1 1
RIPK3 IRAK2 0 0 359 185 1 1
RIPK3 BLNK 0 0 0 151 1 1
RIPK3 NCF1 0 0 72 204 1 1
RIPK3 VNN2 0 0 0 200 1 1
RIPK3 PTPRE 0 0 0 163 1 1
RIPK3 CD19 0 0 113 167 1 1
RIPK3 LOXL1 0 0 0 260 1 1
RIPK3 PRKAA1 0 0 62 166 1 2
RIPK3 PRSS53 0 0 95 152 1 1
RIPK3 TIMD4 0 0 160 184 1 1
RIPK3 LRGUK 0 0 0 161 1 1
RIPK3 FRAT1 0 0 0 183 1 1
RIPK3 VPS37B 0 0 181 181 1 1
RIPK3 PPM1K 0 0 0 198 1 1
RIPK3 FMNL1 0 0 0 180 1 1
RIPK3 FOXO3 0 0 123 193 1 2
RIPK3 IRF8 0 0 0 270 1 1
RIPK3 UAP1L1 0 0 0 169 1 1
RIPK3 CDC42 0 0 73 196 1 2
RIPK3 TLR3 0 600 710 885 1 2
RIPK3 BIRC6 0 0 95 210 1 1
RIPK3 CORO1A 0 0 52 270 1 1
RIPK3 ATG3 0 0 218 275 1 2
RIPK3 CAMK2D 0 800 0 804 1 1
RIPK3 RGS18 0 0 0 271 1 1
RIPK3 CD52 0 0 0 299 1 1
RIPK3 ARHGAP27 0 0 0 209 1 1
RIPK3 CD93 0 0 0 165 1 1
RIPK3 P2RY13 0 0 0 152 1 1
RIPK3 HLA-DOB 0 0 0 159 1 1
RIPK3 FOXP3 0 0 107 202 1 2
RIPK3 PTPN6 0 0 120 294 1 1
RIPK3 TBK1 0 0 276 167 1 2
RIPK3 CORO2A 0 0 0 162 1 1
RIPK3 CLEC5A 0 0 0 155 1 1
RIPK3 PARD6G 0 0 0 189 1 1
RIPK3 TPSAB1 0 0 0 165 1 1
RIPK3 RAC2 0 0 0 286 1 1
RIPK3 GLUL 0 800 253 849 1 1
RIPK3 TRIM29 0 0 63 220 1 1
RIPK3 ALG2 0 0 0 157 1 1
RIPK3 PPP2R3B 0 0 0 154 1 1
RIPK3 LRIT3 0 0 0 165 1 1
RIPK3 STAT5B 0 0 46 150 1 1
RIPK3 RAB7B 0 0 115 192 1 1
RIPK3 VDAC1 0 0 230 245 1 2
RIPK3 TGFB1 0 0 0 181 1 2
RIPK3 PARP10 0 0 0 175 1 1
RIPK3 ADCY4 0 0 0 222 1 1
RIPK3 NKX1-2 0 0 81 238 1 1
RIPK3 PRKCD 0 0 91 198 1 2
RIPK3 MAP3K6 0 0 0 161 1 1
RIPK3 CSF2 0 0 218 218 1 1
RIPK3 EFNB3 0 0 0 168 1 1
RIPK3 GRIK1 0 0 0 150 1 1
RIPK3 F13A1 0 0 0 168 1 1
RIPK3 CDK18 0 0 0 156 1 1
RIPK3 FAS 0 900 467 947 1 2
RIPK3 CIRBP 0 0 112 194 1 1
RIPK3 ATP2A3 0 0 52 157 1 1
RIPK3 WDTC1 0 0 0 164 1 1
RIPK3 MAP3K15 0 0 0 161 1 1
RIPK3 ATP7A 0 0 0 152 1 1
RIPK3 NLRC4 0 0 377 448 1 2
RIPK3 APOL3 0 0 0 214 1 1
RIPK3 NOX4 0 0 81 210 1 2
RIPK3 GPT 0 0 208 257 1 1
RIPK3 MYOF 0 0 289 304 1 1
RIPK3 UBQLN1 0 0 49 152 1 1
RIPK3 PINK1 0 0 251 282 1 2
RIPK3 HSP90AB1 106 800 0 847 1 2
RIPK3 GRIK4 0 0 0 150 1 1
RIPK3 CYLD 0 0 754 767 1 1
RIPK3 ADRM1 0 0 0 156 1 1
RIPK3 TNFSF8 0 0 70 294 1 1
RIPK3 MGAM 0 0 0 193 1 1
RIPK3 SQRDL 0 0 60 183 1 1
RIPK3 AIFM1 117 0 161 425 1 1
RIPK3 PIK3R6 0 0 0 278 1 1
RIPK3 GPR183 0 0 0 171 1 1
RIPK3 UBA7 0 0 0 302 1 1
RIPK3 PPM1E 0 0 0 198 1 1
RIPK3 DENR 0 0 232 260 1 1
RIPK3 ENSG00000270024 0 0 0 209 1 1
RIPK3 PPM1F 0 0 0 198 1 1
RIPK3 CLIP4 0 0 0 163 1 1
RIPK3 ZBTB7A 0 0 0 180 1 1
RIPK3 LSP1 0 0 69 248 1 1
RIPK3 MFN1 0 0 188 220 1 2
RIPK3 RAP2C 0 0 61 160 1 1
RIPK3 ANKRD44 0 0 0 157 1 1
RIPK3 SPTBN1 96 0 48 167 1 1
RIPK3 SOD1 0 0 181 224 1 2
RIPK3 LTA 0 0 94 283 1 1
RIPK3 PP2D1 0 0 0 198 1 1
RIPK3 ABI1 0 0 0 150 1 1
RIPK3 LRIT1 0 0 0 165 1 1
RIPK3 GRB2 0 0 49 177 1 1
RIPK3 NFKBIE 0 0 48 158 1 1
RIPK3 EYS 0 0 0 181 1 1
RIPK3 DAPK1 105 0 144 192 1 2
RIPK3 CLIC5 0 0 0 182 1 1
RIPK3 ETNK2 0 0 0 159 1 1
RIPK3 JUN 0 0 284 311 1 2
RIPK3 TRIO 0 0 0 167 1 1
RIPK3 DIDO1 0 0 0 182 1 1
RIPK3 ENSG00000173366 0 0 327 369 1 1
RIPK3 PYGB 0 800 0 809 1 1
RIPK3 S1PR4 0 0 0 221 1 1
RIPK3 CORO2B 0 0 0 162 1 1
RIPK3 GZMA 0 0 81 215 1 1
RIPK3 DAPP1 0 0 48 178 1 1
RIPK3 ITGAL 0 0 0 176 1 1
RIPK3 STXBP5 0 0 0 158 1 1
RIPK3 PADI4 0 0 167 187 1 1
RIPK3 PIK3CG 0 0 60 210 1 1
RIPK3 AIF1 0 0 181 340 1 2
RIPK3 ALG8 0 0 62 169 1 1
RIPK3 MYO3A 0 0 0 155 1 1
RIPK3 DNTT 0 0 243 242 1 1
RIPK3 PSD4 0 0 0 163 1 1
RIPK3 MMP9 0 0 142 205 1 2
RIPK3 MAPK3 0 0 161 276 1 2
RIPK3 HLA-DMB 0 0 0 198 1 1
RIPK3 SLC11A2 0 0 0 182 1 1
RIPK3 GIMAP4 0 0 0 252 1 1
RIPK3 BNIP3 0 0 193 196 1 2
RIPK3 SQSTM1 0 0 323 367 1 2
RIPK3 MFNG 0 0 0 167 1 1
RIPK3 SELP 0 0 0 169 1 1
RIPK3 GNA14 0 0 0 158 1 1
RIPK3 ATG13 0 0 173 173 1 2
RIPK3 LIMA1 98 0 0 155 1 1
RIPK3 EPRS 106 0 0 178 1 1
RIPK3 GRAP2 0 0 0 210 1 1
RIPK3 TLE6 270 0 0 285 1 1
RIPK3 SELL 0 0 107 280 1 1
RIPK3 LTB 0 0 0 203 1 1
RIPK3 BCL3 0 0 0 196 1 1
RIPK3 HSP90AA1 106 800 466 910 1 2
RIPK3 ZSCAN20 270 0 0 300 1 1
RIPK3 RNF8 0 0 0 239 1 1
RIPK3 IGDCC3 0 0 0 184 1 1
RIPK3 ICAM1 0 0 138 187 1 2
RIPK3 HUNK 0 0 0 158 1 1
RIPK3 SMDT1 0 0 176 175 1 1
RIPK3 BCL10 0 0 193 232 1 1
RIPK3 XKR8 0 0 216 227 1 1
RIPK3 PTPRC 0 0 272 439 1 1
RIPK3 AURKA 0 0 121 262 1 2
RIPK3 BAX 0 0 261 261 1 2
RIPK3 F10 0 0 51 165 1 1
RIPK3 GNA12 0 0 48 183 1 1
RIPK3 ENSG00000249884 0 0 54 158 1 1
RIPK3 BID 0 0 257 273 1 2
RIPK3 CD1C 0 0 0 151 1 1
RIPK3 FGL2 0 0 0 193 1 1
RIPK3 NCF4 0 0 0 333 1 1
RIPK3 MB21D1 0 0 253 252 1 1
RIPK3 BUB1B 270 0 61 316 1 1
RIPK3 VPS35 0 0 0 171 1 2
RIPK3 CDK16 0 0 0 157 1 1
RIPK3 DDX41 0 0 81 158 1 1
RIPK3 SGK494 0 0 0 194 1 1
RIPK3 FKBP4 157 0 0 180 1 1
RIPK3 AGER 0 0 166 214 1 2
RIPK3 EPHA4 280 0 0 292 1 1
RIPK3 PPP1CB 100 0 0 183 1 1
RIPK3 ALK 0 0 0 177 1 2
RIPK3 SIGLEC9 0 0 57 199 1 1
RIPK3 PIK3AP1 0 0 0 171 1 1
RIPK3 TRADD 0 900 918 992 1 1
RIPK3 SRGN 0 0 0 213 1 1
RIPK3 CASP7 0 0 391 418 1 1
RIPK3 CSNK1D 0 0 0 164 1 1
RIPK3 TYROBP 0 0 0 332 1 1
RIPK3 CDC37 222 600 228 771 1 1
RIPK3 CCL2 0 0 268 284 1 2
RIPK3 ALB 0 0 245 258 1 2
RIPK3 CD68 0 0 86 175 1 2
RIPK3 SGK2 0 0 0 211 1 1
RIPK3 CARD17 0 0 0 176 1 1
RIPK3 IL16 0 0 0 261 1 1
RIPK3 OTULIN 0 0 324 331 1 1
RIPK3 BPGM 0 0 0 181 1 1
RIPK3 ANXA8 0 0 170 169 1 1
RIPK3 BIRC3 270 900 455 968 1 1
RIPK3 IL4 0 0 170 169 1 1
RIPK3 NUMB 0 0 0 159 1 1
RIPK3 CHD1 0 0 0 171 1 1
RIPK3 PCSK1 0 0 804 828 1 1
RIPK3 NACC1 0 0 67 151 1 1
RIPK3 PELI1 270 800 173 874 1 1
RIPK3 RASAL3 0 0 0 316 1 1
RIPK3 GAK 0 0 0 152 1 1
RIPK3 TMEM176B 0 0 0 157 1 1
RIPK3 GNAZ 0 0 0 177 1 1
RIPK3 PDP1 0 0 0 201 1 1
RIPK3 RAC3 0 0 0 153 1 2
RIPK3 PPM1L 0 0 0 198 1 1
RIPK3 CYCS 0 0 459 459 1 2
RIPK3 TRAF6 0 0 247 313 1 2
RIPK3 COLGALT1 0 0 249 248 1 1
RIPK3 CXCL9 0 0 74 153 1 1
RIPK3 PPARA 0 0 117 150 1 2
RIPK3 CCR2 0 0 118 232 1 2
RIPK3 CLEC12A 0 0 0 226 1 1
RIPK3 CYP2E1 0 0 160 173 1 2
RIPK3 HSP90B1 0 0 60 264 1 1
RIPK3 PTPRK 128 0 0 181 1 1
RIPK3 PDZD2 0 0 0 190 1 1
RIPK3 HSPA4 0 0 170 252 1 1
RIPK3 CCR1 0 0 54 188 1 1
RIPK3 FSTL3 0 0 0 188 1 1
RIPK3 PPP2CB 0 0 0 151 1 1
RIPK3 CHKA 0 0 0 159 1 1
RIPK3 P2RX7 0 0 150 172 1 2
RIPK3 DIABLO 0 0 665 678 1 2
RIPK3 SPATA2 0 0 194 194 1 1
RIPK3 ARHGDIB 0 0 0 245 1 1
RIPK3 GPX4 0 0 427 444 1 2
RIPK3 CLIC2 0 0 0 150 1 1
RIPK3 LILRB2 0 0 0 306 1 1
RIPK3 SLA 0 0 0 196 1 1
RIPK3 GAB4 0 0 0 186 1 1
RIPK3 MAPK8 0 0 294 304 1 2
RIPK3 PHF8 0 0 0 237 1 1
RIPK3 RNF17 0 0 117 646 1 1
RIPK3 LY75 0 0 0 191 1 1
RIPK3 ANKRD7 0 0 104 177 1 1
RIPK3 CASP10 0 0 416 703 1 1
RIPK3 TFEC 0 0 0 227 1 1
RIPK3 CLEC4A 0 0 0 155 1 1
RIPK3 TNFRSF12A 0 0 166 179 1 1
RIPK3 FLNA 106 0 0 197 1 1
RIPK3 ST13 0 0 181 181 1 2
RIPK3 IFITM2 0 0 0 168 1 1
RIPK3 STK11 0 0 66 231 1 2
RIPK3 ALG11 0 0 0 157 1 1
RIPK3 RB1CC1 0 0 353 353 1 2
RIPK3 TAGAP 0 0 0 300 1 1
RIPK3 ABI3 0 0 0 252 1 1
RIPK3 APC2 0 0 0 151 1 1
RIPK3 PARK2 270 0 140 386 1 1
RIPK3 IFNA1 0 0 218 218 1 1
RIPK3 PPP5C 0 0 66 155 1 1
RIPK3 FCGR1B 0 0 0 167 1 1
RIPK3 CBLB 0 0 45 206 1 1
RIPK3 UCK2 0 0 0 171 1 1
RIPK3 ACP5 0 0 0 256 1 1
RIPK3 GNAQ 0 0 0 158 1 1
RIPK3 WDR64 0 0 0 176 1 1
RIPK3 MEFV 0 0 391 414 1 1
RIPK3 PIM1 0 0 0 176 1 1
RIPK3 NR4A1 0 0 123 154 1 2
RIPK3 MELK 0 0 0 158 1 1
RIPK3 BRD4 0 0 95 221 1 2
RIPK3 CALM3 106 0 0 163 1 1
RIPK3 APAF1 0 0 407 460 1 2
RIPK3 GNAT1 0 0 0 177 1 1
RIPK3 VAMP8 0 0 67 161 1 2
RIPK3 TP53RK 0 0 0 196 1 1
RIPK3 NLRC5 0 0 0 158 1 1
RIPK3 C19orf24 0 0 0 168 1 1
RIPK3 HIST1H1B 270 0 0 270 1 1
RIPK3 ETNK1 0 0 0 159 1 1
RIPK3 RASGRP3 0 0 0 154 1 1
RIPK3 RHBDL3 0 0 0 166 1 1
RIPK3 CD300C 0 0 125 283 1 1
RIPK3 PTPN22 0 0 45 169 1 1
RIPK3 MYO7B 0 0 0 155 1 1
RIPK3 FHOD3 0 0 0 163 1 1
RIPK3 MAP3K13 0 0 731 388 1 1
RIPK3 CFLAR 0 900 847 986 1 2
RIPK3 PPP1CC 98 0 0 187 1 1
RIPK3 TNFRSF4 0 0 48 239 1 1
RIPK3 LAMP1 0 0 182 211 1 2
RIPK3 TP53 0 0 324 349 1 2
RIPK3 PTPRCAP 0 0 0 162 1 1
RIPK3 LRIG1 0 0 60 155 1 1
RIPK3 TIMM50 106 0 0 179 1 1
RIPK3 EDA 0 0 0 295 1 1
RIPK3 ZBP1 270 800 927 991 1 1
RIPK3 MAP1A 0 0 97 155 1 2
RIPK3 NFKBIZ 0 0 0 152 1 1
RIPK3 MAP3K7 0 0 344 161 1 2
RIPK3 MYL6 118 0 0 173 1 1
RIPK3 APBB1IP 0 0 0 290 1 1
RIPK3 CARD9 0 0 158 208 1 1
RIPK3 DOK3 0 0 0 156 1 1
RIPK3 VRK3 0 0 47 169 1 1
RIPK3 FHOD1 0 0 0 163 1 1
RIPK3 LSM14A 0 0 49 182 1 1
RIPK3 PSTPIP2 0 0 180 213 1 1
RIPK3 GIMAP6 0 0 0 282 1 1
RIPK3 MTOR 0 0 193 270 1 2
RIPK3 TRIB2 0 0 0 162 1 1
RIPK3 GZMB 0 0 102 328 1 1
RIPK3 MYL6B 105 0 0 160 1 1
RIPK3 PLEK 0 0 90 323 1 1
RIPK3 ENDOG 0 0 235 235 1 1
RIPK3 STAT1 0 0 260 341 1 2
RIPK3 GNA13 0 0 0 177 1 1
RIPK3 DOK2 0 0 0 228 1 1
RIPK3 PIK3C3 0 0 233 372 1 2
RIPK3 POLR2C 0 0 45 157 1 1
RIPK3 FOLR2 0 0 0 166 1 1
RIPK3 ENSG00000268500 0 0 0 214 1 1
RIPK3 CXCL8 0 0 217 241 1 2
RIPK3 VRK1 0 0 0 164 1 1
RIPK3 PRRC2A 0 0 171 171 1 1
RIPK3 IKBKE 0 0 81 189 1 1
RIPK3 IGSF9B 0 0 0 156 1 1
RIPK3 WNT2B 0 0 0 172 1 1
RIPK3 PASK 0 0 0 162 1 1
RIPK3 ALG1 0 0 53 176 1 1
RIPK3 C3AR1 0 0 74 202 1 1
RIPK3 ARL8A 0 0 0 151 1 1
RIPK3 LRG1 0 0 53 214 1 1
RIPK3 MFN2 0 0 150 240 1 2
RIPK3 DCAF6 0 0 0 164 1 1
RIPK3 CTNNB1 0 0 139 256 1 2
RIPK3 HRAS 0 0 136 242 1 2
RIPK3 GIMAP5 0 0 0 237 1 1
RIPK3 RELA 0 650 244 733 1 2
RIPK3 NFKB1 0 650 90 716 1 2
RIPK3 NABP1 0 0 170 169 1 1
RIPK3 TLR10 0 0 90 227 1 1
RIPK3 STAT4 0 0 0 201 1 1
RIPK3 ARHGAP4 0 0 0 163 1 1
RIPK3 CASP6 0 0 260 303 1 1
RIPK3 DPEP2 0 0 0 183 1 1
RIPK3 TSSK3 0 0 0 239 1 1
RIPK3 MAP2K7 0 0 161 173 1 1
RIPK3 SPATA45 0 0 181 181 1 1
RIPK3 ALG1L 0 0 0 165 1 1
RIPK3 GAPDH 0 0 379 402 1 2
RIPK3 EFNB1 0 0 0 168 1 1
RIPK3 GSDMD 0 0 612 643 1 2
RIPK3 GSG2 0 0 96 156 1 1
RIPK3 GZMM 0 0 143 201 1 1
RIPK3 APC 0 0 0 151 1 1
RIPK3 PPID 0 0 280 292 1 1
RIPK3 KLHDC7B 0 0 0 168 1 1
RIPK3 ARHGAP30 0 0 0 214 1 1
RIPK3 ACCS 0 0 0 150 1 1
RIPK3 ESRRA 0 0 69 152 1 1
RIPK3 GRIK2 0 0 0 150 1 1
RIPK3 SIRT2 0 0 921 921 1 2
RIPK3 GRID2IP 0 0 0 260 1 1
RIPK3 ODF3B 0 0 0 185 1 1
RIPK3 CTNND1 157 0 0 190 1 1
RIPK3 MAP1LC3B2 0 0 0 159 1 1
RIPK3 TNFSF13 0 0 0 169 1 1
RIPK3 CD3E 0 0 49 156 1 1
RIPK3 TSSK4 0 0 0 232 1 1
RIPK3 HLA-B 0 0 0 168 1 1
RIPK3 CORO1C 100 0 0 214 1 1
RIPK3 ITGB2 0 0 53 362 1 1
RIPK3 KRAS 0 0 120 234 1 2
RIPK3 RAI14 100 0 0 174 1 1
RIPK3 PDHX 0 0 46 244 1 1
RIPK3 SLC2A9 0 0 0 201 1 1
RIPK3 KDM2B 0 0 95 180 1 1
RIPK3 KIAA1614 0 0 0 189 1 1
RIPK3 ARRDC5 0 0 0 179 1 1
RIPK3 TNIP2 0 0 136 161 1 1
RIPK3 RNASE6 0 0 0 254 1 1
RIPK3 TNIP1 0 0 166 220 1 1
RIPK3 STAT5A 0 0 85 267 1 1
RIPK3 BIRC7 0 0 126 218 1 1
RIPK3 SOCS3 0 0 90 173 1 1
RIPK3 MNDA 0 0 0 335 1 1
RIPK3 IGSF6 0 0 0 156 1 1
RIPK3 CCT7 98 0 0 191 1 1
RIPK3 FASLG 0 900 508 949 1 1
RIPK3 CARD11 0 0 172 251 1 1
RIPK3 HLA-DRA 0 0 0 213 1 1
RIPK3 BIN2 0 0 0 215 1 1
RIPK3 POTEH 0 0 112 156 1 1
RIPK3 ENSG00000251246 0 0 0 182 1 1
RIPK3 HSH2D 0 0 210 252 1 1
RIPK3 PPM1A 0 0 0 223 1 1
RIPK3 MAPK11 0 0 46 248 1 1
RIPK3 DUSP1 0 0 74 192 1 1
RIPK3 NCAPD2 0 0 0 177 1 1
RIPK3 DNAJC10 0 0 0 166 1 1
RIPK3 GYS1 0 0 0 157 1 1
RIPK3 TLR6 0 0 150 251 1 1
RIPK3 VSIG4 0 0 0 159 1 1
RIPK3 BECN1 0 0 392 412 1 2
RIPK3 EEF1G 0 0 0 195 1 1
RIPK3 HLA-DPA1 0 0 0 207 1 1
RIPK3 CAMK2B 0 800 53 805 1 1
RIPK3 FBXL19 0 0 0 194 1 1
RIPK3 NUAK2 0 0 0 164 1 1
RIPK3 KANK2 0 0 310 366 1 1
RIPK3 MAPK15 0 0 0 163 1 1
RIPK3 TRIM22 0 0 0 150 1 1
RIPK3 RAB20 0 0 72 198 1 1
RIPK3 CYBB 0 800 181 859 1 2
RIPK3 FPR3 0 0 0 154 1 1
RIPK3 GPR65 0 0 43 203 1 1
RIPK3 RNASE2 0 0 0 151 1 1
RIPK3 TNFRSF10B 0 900 325 930 1 2
RIPK3 STK17B 0 0 0 215 1 1
RIPK3 CTSS 0 0 83 275 1 1
RIPK3 PPM1B 0 0 390 537 1 1
RIPK3 RASGRP4 0 0 0 153 1 1
RIPK3 CASP3 0 0 629 645 1 2
RIPK3 NKG7 0 0 0 214 1 1
RIPK3 PTGS2 0 0 97 162 1 2
RIPK3 LTK 0 0 0 208 1 1
RIPK3 CARD16 0 0 0 286 1 1
RIPK3 NCAPH 0 0 0 178 1 1
RIPK3 CD53 0 0 0 294 1 1
RIPK3 NLRP3 0 0 655 686 1 2
RIPK3 REL 0 0 194 260 1 2
RIPK3 UTP11L 270 0 0 287 1 1
RIPK3 CTSZ 0 0 0 156 1 1
RIPK3 RIPK1 981 800 990 997 1 2
RIPK3 PIK3CD 0 0 0 162 1 1
RIPK3 SMPD1 0 0 172 184 1 1
RIPK3 ATG16L1 0 0 252 257 1 2
RIPK3 NOD2 0 0 321 448 1 2
RIPK3 NRROS 0 0 0 178 1 1
RIPK3 DUSP2 0 0 64 195 1 1
RIPK3 INSRR 0 0 0 186 1 1
RIPK3 MRC1 0 0 122 180 1 1
RIPK3 EPSTI1 0 0 0 154 1 1
RIPK3 RPS27A 106 900 0 913 1 1
RIPK3 CNOT3 0 0 120 165 1 1
RIPK3 CDKN2A 0 0 93 167 1 2
RIPK3 FGD3 0 0 0 204 1 1
RIPK3 PPP6C 0 0 82 184 1 1
RIPK3 IL18RAP 0 0 0 181 1 1
RIPK3 ATP7B 0 0 0 152 1 1
RIPK3 TNFRSF10C 0 0 97 152 1 1
RIPK3 MPLKIP 0 0 134 178 1 1
RIPK3 OGT 0 900 82 910 1 2
RIPK3 CTSG 0 0 95 355 1 1
RIPK3 CCL3 0 0 137 228 1 1
RIPK3 FCGR3B 0 0 57 186 1 1
RIPK3 ZG16B 130 0 0 150 1 1
RIPK3 GIMAP7 0 0 0 213 1 1
RIPK3 GDF15 0 0 0 173 1 1
RIPK3 IRAK4 0 0 207 207 1 1
RIPK3 OXER1 0 0 0 155 1 1
RIPK3 FLT3 0 0 97 176 1 2
RIPK3 IL10 0 0 225 240 1 2
RIPK3 UBASH3A 0 0 107 194 1 1
RIPK3 SLC9C2 0 0 0 175 1 1
RIPK3 DSTYK 0 0 260 162 1 1
RIPK3 MCEMP1 0 0 0 151 1 1
RIPK3 BST2 0 0 481 496 1 1
RIPK3 ACSL4 0 0 204 235 1 1
RIPK3 STK40 0 0 75 210 1 1
RIPK3 NLRP6 0 0 116 206 1 1
RIPK3 FPR1 0 0 112 179 1 1
RIPK3 LTA4H 0 0 112 193 1 1
RIPK3 TTC32 0 0 141 196 1 1
RIPK3 NME8 270 0 0 430 1 1
RIPK3 AASDHPPT 0 0 208 208 1 1
RIPK3 CEACAM3 0 0 0 151 1 1
RIPK3 CYTIP 0 0 0 322 1 1
RIPK3 FERMT3 0 0 0 242 1 1
RIPK3 TSSK6 0 0 0 228 1 1
RIPK3 CORO1B 0 0 0 162 1 1
RIPK3 CD79A 0 0 0 198 1 1
RIPK3 CLEC4E 0 0 218 267 1 1
RIPK3 DOCK8 0 0 0 162 1 1
RIPK3 NUAK1 0 0 0 168 1 1
RIPK3 PIM2 0 0 0 248 1 1
RIPK3 IFNB1 0 0 620 620 1 1
RIPK3 CHKB 0 0 0 179 1 1
RIPK3 DFNA5 0 0 391 390 1 1
RIPK3 PDK4 0 0 0 197 1 1
RIPK3 PDCD1 0 0 97 162 1 2
RIPK3 OPTN 0 0 340 367 1 2
RIPK3 INPP5K 157 0 0 170 1 1
RIPK3 CAMK1 0 0 0 174 1 1
RIPK3 ILKAP 0 0 0 198 1 1
RIPK3 ANKRD22 0 0 0 173 1 1
RIPK3 CALCOCO2 0 0 164 163 1 2
RIPK3 MIB1 0 0 0 188 1 1
RIPK3 IRF1 0 0 203 289 1 2
RIPK3 C1QA 0 0 0 157 1 1
RIPK3 CXCR3 0 0 45 168 1 1
RIPK3 TIFAB 0 0 0 196 1 1
RIPK3 VAV1 0 0 197 257 1 1
RIPK3 PSKH1 0 0 0 160 1 1
RIPK3 NCF2 0 0 0 311 1 1
RIPK3 MST1R 0 0 0 181 1 1
RIPK3 SPHK1 0 0 387 396 1 2
RIPK3 SLC15A3 0 0 62 237 1 1
RIPK3 EFNA2 0 0 0 168 1 1
RIPK3 MAP1LC3B 0 0 282 370 1 2
RIPK3 RIN3 0 0 0 165 1 1
RIPK3 PIGA 0 0 0 157 1 1
RIPK3 UBC 0 900 0 906 1 2
RIPK3 CAMK2A 0 800 45 806 1 2
RIPK3 RIPK4 0 0 335 260 1 1
RIPK3 CD300LB 0 0 0 282 1 1
RIPK3 MAPKAPK3 0 0 134 243 1 1
RIPK3 ELANE 0 0 138 221 1 1
RIPK3 SPRED2 0 0 0 158 1 2
RIPK3 IL1R2 0 0 66 252 1 1
RIPK3 NFKB2 0 650 141 725 1 1
RIPK3 TNFAIP3 0 800 321 870 1 2
RIPK3 RAB7A 0 0 113 167 1 2
RIPK3 ZMPSTE24 0 0 0 174 1 1
RIPK3 SLC17A9 0 0 57 177 1 1
RIPK3 S100A9 0 0 0 213 1 1
RIPK3 IFI16 0 0 151 194 1 1
RIPK3 BMF 0 0 218 246 1 1
RIPK3 RUFY4 0 0 0 178 1 1
RIPK3 FBXW2 0 0 54 151 1 1
RIPK3 MS4A14 0 0 0 262 1 1
RIPK3 PARD6A 0 0 0 189 1 1
RIPK3 IRF7 0 0 232 321 1 1
RIPK3 ARHGAP9 0 0 0 220 1 1
RIPK3 TLDC2 0 0 0 155 1 1
RIPK3 TNF 0 0 720 764 1 2
RIPK3 NBR1 0 0 107 201 1 2
RIPK3 IFITM1 0 0 81 251 1 1
RIPK3 STK32C 0 0 0 196 1 1
RIPK3 C22orf29 0 0 261 261 1 1
RIPK3 TRAP1 0 0 0 174 1 2
RIPK3 IL1RN 0 0 75 216 1 1
RIPK3 ANKLE1 0 0 63 201 1 1
RIPK3 FIS1 0 0 151 184 1 2
RIPK3 NAIP 0 0 162 244 1 1
RIPK3 CLEC10A 0 0 0 226 1 1
RIPK3 CDK3 0 0 0 190 1 1
RIPK3 RBFOX3 0 0 166 179 1 1
RIPK3 SLC7A11 0 0 182 210 1 2
RIPK3 STIP1 157 0 0 193 1 1
RIPK3 CRIP1 0 0 0 181 1 1
RIPK3 FUT7 0 0 0 169 1 1
RIPK3 PPP2R3A 0 0 45 192 1 1
RIPK3 CTLA4 0 0 170 214 1 2
RIPK3 GRID1 0 0 0 150 1 2
RIPK3 IFI44 0 0 66 209 1 1
RIPK3 SSH3 0 0 0 165 1 1
RIPK3 RNASEL 0 0 73 188 1 1
RIPK3 BAK1 0 0 242 258 1 2
RIPK3 ZNF831 0 0 0 159 1 1
RIPK3 NUMBL 0 0 0 159 1 1
RIPK3 CAT 0 0 153 215 1 2
RIPK3 ARHGAP25 0 0 0 154 1 1
RIPK3 PDPK1 0 0 0 164 1 2
RIPK3 TTBK1 0 0 0 164 1 1
RIPK3 RPS6KB1 0 0 81 220 1 2
RIPK3 FCGR1A 0 0 84 201 1 1
RIPK3 P2RY10 0 0 0 160 1 1
RIPK3 HSPA9 106 0 66 240 1 1
RIPK3 CBL 0 0 57 216 1 1
RIPK3 SNX20 0 0 0 185 1 1
RIPK3 GNLY 0 0 55 153 1 1
RIPK3 HK3 0 0 0 294 1 1
RIPK3 BCL2L2 0 0 120 157 1 1
RIPK3 DVL2 0 0 57 159 1 2
RIPK3 RAB44 0 0 0 185 1 1
RIPK3 ALDH2 0 0 134 184 1 2
RIPK3 CD274 0 0 134 191 1 2
RIPK3 CSF2RB 0 0 0 353 1 1
RIPK3 HLA-E 0 0 0 175 1 1
RIPK3 CLIC3 0 0 0 150 1 1
RIPK3 MCU 0 0 150 169 1 2
RIPK3 STAP1 0 0 71 184 1 1
RIPK3 YWHAB 0 0 0 171 1 1
RIPK3 SPRED1 0 0 0 158 1 1
RIPK3 SAMD9L 0 0 0 183 1 1
RIPK3 GPN2 0 0 0 158 1 1
RIPK3 GRAP 0 0 0 292 1 1
RIPK3 DOCK2 0 0 0 190 1 1
RIPK3 RABGEF1 0 0 0 168 1 1
RIPK3 SLC25A5 106 0 60 154 1 1
RIPK3 FRMPD2 0 0 0 193 1 1
RIPK3 FLT1 0 0 242 202 1 1
RIPK3 EIF2AK3 0 0 165 194 1 2
RIPK3 ENAH 0 0 0 158 1 1
RIPK3 STK25 0 0 0 168 1 1
RIPK3 TEN1-CDK3 0 0 0 173 1 1
RIPK3 STAT6 0 0 0 208 1 1
RIPK3 TNFSF12 0 0 193 252 1 1
RIPK3 GLTP 0 0 181 279 1 1
RIPK3 HMOX1 0 0 207 242 1 2
RIPK3 TICAM2 0 600 0 635 1 1
RIPK3 RHOH 0 0 0 158 1 1
RIPK3 PTPN7 0 0 0 151 1 1
RIPK3 TOMM20 0 0 193 210 1 2
RIPK3 P2RX1 0 0 0 237 1 1
RIPK3 STX17 0 0 135 211 1 2
RIPK3 PTPRQ 0 0 0 181 1 1
RIPK3 ERAL1 0 0 0 156 1 1
RIPK3 BNIP3L 0 0 159 158 1 2
RIPK3 C1QB 0 0 0 167 1 1
RIPK3 OR6K3 0 0 165 165 1 1
RIPK3 HACE1 0 0 74 216 1 1
RIPK3 PPM1D 0 0 63 216 1 1
RIPK3 HCAR3 0 0 0 151 1 1
RIPK3 CAMK1G 0 0 0 159 1 1
RIPK3 POLRMT 0 0 0 165 1 1
RIPK3 STK3 0 0 0 155 1 1
RIPK3 CD2 0 0 0 214 1 1
RIPK3 CYTH4 0 0 0 214 1 1
RIPK3 AKT1 0 0 290 230 1 2
RIPK3 GBP2 0 0 166 314 1 1
RIPK3 CAPN1 0 0 82 152 1 2
RIPK3 PHF2 0 0 0 193 1 1
RIPK3 LY96 0 600 92 660 1 1
RIPK3 SP140 0 0 0 173 1 1
RIPK3 CD48 0 0 0 214 1 1
RIPK3 SGK3 0 0 0 209 1 1
RIPK3 CD4 0 0 294 404 1 2
RIPK3 GNAL 0 0 0 158 1 1
RIPK3 UCKL1 0 0 0 171 1 1
RIPK3 BRDT 0 0 0 155 1 1
RIPK3 ATF6 0 0 134 172 1 2
RIPK3 IKBKB 0 900 376 915 1 2
RIPK3 ALOX5AP 0 0 0 210 1 1
RIPK3 PANX1 0 0 207 207 1 1
RIPK3 PHKG2 0 0 60 161 1 1
RIPK3 PDK3 0 0 0 197 1 1
RIPK3 XIAP 270 900 519 966 1 2
RIPK3 GMFG 0 0 0 151 1 1
RIPK3 ARPIN 0 0 124 419 1 1
RIPK3 IL24 270 0 53 321 1 2
RIPK3 BIRC5 0 0 66 159 1 2
RIPK3 ITPK1 0 0 195 223 1 1
RIPK3 BIRC8 0 0 113 212 1 1
RIPK3 MALT1 0 0 194 225 1 1
RIPK3 CXCL10 0 0 210 284 1 2
RIPK3 PYCARD 0 0 343 418 1 2
RIPK3 TLR9 0 0 327 398 1 2
RIPK3 SDR39U1 0 0 134 511 1 1
RIPK3 GYS2 0 0 0 157 1 1
RIPK3 IRF3 0 0 391 400 1 2
RIPK3 BBC3 0 0 182 181 1 2
RIPK3 SLAMF1 0 0 0 242 1 1
RIPK3 TCIRG1 0 0 0 223 1 1
RIPK3 RIPK2 0 0 470 221 1 2
RIPK3 FUNDC1 0 0 278 278 1 2
RIPK3 CALR 0 0 167 191 1 1
RIPK3 CD8A 0 0 325 359 1 1
RIPK3 ADAM8 0 0 0 194 1 1
RIPK3 SIGLEC7 0 0 0 179 1 1
RIPK3 PSMB8 0 0 0 156 1 1
RIPK3 CSNK1A1 0 0 96 174 1 1
RIPK3 CD69 0 0 90 173 1 1
RIPK3 MIB2 0 0 91 239 1 1
RIPK3 RTP4 0 0 0 181 1 1
RIPK3 CCR5 0 0 72 251 1 1
RIPK3 IL17RA 0 0 104 296 1 1
RIPK3 LAMP2 0 0 82 170 1 2
RIPK3 CCRL2 0 0 60 239 1 1
RIPK3 YWHAE 96 0 0 223 1 1
RIPK3 TICAM1 270 800 580 938 1 2
RIPK3 TMEM173 0 0 125 247 1 1
RIPK3 TNIP3 0 0 122 262 1 1
RIPK3 RHOT1 0 0 113 211 1 1
RIPK3 NAALADL1 0 0 0 176 1 1
RIPK3 AURKC 0 0 0 178 1 1
RIPK3 BATF 0 0 0 199 1 1
RIPK3 MAPK12 0 0 0 256 1 1
RIPK3 BRD3 0 0 0 189 1 1
RIPK3 SIGLEC1 0 0 0 217 1 1
RIPK3 IL10RA 0 0 0 271 1 1
RIPK3 BCL2L11 0 0 310 321 1 2
RIPK3 PPP1R16B 0 0 0 152 1 1
RIPK3 MAP2K3 0 0 72 177 1 1
RIPK3 VRK2 0 0 0 164 1 1
RIPK3 HSPA1A 106 0 82 228 1 1
RIPK3 ZFP36 0 0 0 163 1 1
RIPK3 MST4 0 0 0 161 1 1
RIPK3 HLA-DRB1 0 0 0 181 1 1
RIPK3 TNFSF10 0 900 460 950 1 2
RIPK3 EVI2B 0 0 0 213 1 1
RIPK3 CASP1 0 0 632 760 1 2
RIPK3 CD74 0 0 0 235 1 1
RIPK3 CHEK1 0 0 54 205 1 2
RIPK3 KEAP1 0 0 172 228 1 2
RIPK3 B2M 0 0 46 154 1 1
RIPK3 ROS1 0 0 0 177 1 1
RIPK3 CSNK1E 0 0 0 164 1 1
RIPK3 FCGR2B 0 0 96 228 1 1
RIPK3 ACTB 0 0 424 464 1 2
RIPK3 THEMIS2 0 0 0 171 1 1
RIPK3 CD40 0 0 144 306 1 2
RIPK3 STUB1 0 600 241 704 1 2
RIPK3 HTRA2 0 0 234 262 1 1
RIPK3 MYO1G 0 0 0 177 1 1
RIPK3 TFEB 0 0 180 289 1 2
RIPK3 MS4A1 0 0 0 153 1 1
RIPK3 GPR84 0 0 95 201 1 1
RIPK3 PDK2 0 0 0 197 1 1
RIPK3 GABARAPL1 0 0 144 199 1 2
RIPK3 RHOG 0 0 0 172 1 1
RIPK3 NIM1K 0 0 0 255 1 1
RIPK3 CBLC 0 0 0 203 1 1
RIPK3 MLKL 870 800 990 989 1 2
RIPK3 SEMA4A 0 0 0 157 1 1
RIPK3 FYB 0 0 0 207 1 1
RIPK3 TLR5 0 0 127 207 1 1
RIPK3 LLGL2 0 0 0 158 1 1
RIPK3 JUP 0 0 0 171 1 1
RIPK3 TNFRSF14 0 0 0 281 1 1
RIPK3 HSPA8 106 0 48 200 1 2
RIPK3 RHOA 0 0 109 200 1 2
RIPK3 ABTB1 0 0 0 190 1 1
RIPK3 PARP1 0 0 391 423 1 2
RIPK3 SNX15 0 0 0 204 1 1
RIPK3 DDX58 0 0 383 407 1 1
RIPK3 AIM2 0 0 378 397 1 2
RIPK3 CDK6 0 0 0 161 1 2
RIPK3 YWHAG 0 0 0 165 1 1
RIPK3 MAPKAPK2 0 0 140 444 1 1
RIPK3 CHMP3 0 0 54 158 1 1
RIPK3 CCL4 0 0 103 229 1 1
RIPK3 IL1A 0 0 367 367 1 1
RIPK3 MAVS 0 0 529 547 1 2
RIPK3 LLGL1 0 0 0 158 1 1
RIPK3 RNF31 0 0 507 514 1 1
RIPK3 STK32A 0 0 0 190 1 1
RIPK3 PIK3R5 0 0 0 213 1 1
RIPK3 FKBP5 157 0 0 180 1 1
RIPK3 PIWIL4 0 0 0 162 1 1
RIPK3 AOAH 0 0 0 175 1 1
RIPK3 TNFAIP8L2 0 0 0 238 1 1
RIPK3 LRRFIP1 0 0 90 163 1 1
RIPK3 PPM1G 0 0 0 198 1 1
RIPK3 CASP8 875 900 988 999 1 2
RIPK3 IGLL5 0 0 0 151 1 1
RIPK3 ALG1L2 0 0 0 165 1 1
RIPK3 CD276 0 0 67 179 1 1
RIPK3 TNFRSF10A 0 900 393 937 1 1
RIPK3 DBN1 98 0 54 157 1 1
RIPK3 B3GNT8 0 0 0 175 1 1
RIPK3 SVEP1 0 0 60 176 1 1
RIPK3 ARL11 0 0 0 166 1 1
RIPK3 GLUD2 0 800 0 806 1 1
RIPK3 SETD7 0 0 0 171 1 1
RIPK3 MS4A7 0 0 0 159 1 1
RIPK3 IL17A 0 0 170 169 1 2
RIPK3 IMMT 0 0 63 157 1 1
RIPK3 TLR7 0 0 397 455 1 2
RIPK3 MAPK9 0 0 174 274 1 2
RIPK3 ZNF7 0 0 219 251 1 1
RIPK3 PSKH2 0 0 51 175 1 1
RIPK3 MYL12A 118 0 0 173 1 1
RIPK3 HK1 0 0 95 151 1 1
RIPK3 CASP9 0 0 459 471 1 2
RIPK3 RPS6KA4 0 0 45 158 1 1
RIPK3 LRMP 0 0 0 175 1 1
RIPK3 TRIB1 0 0 0 162 1 1
RIPK3 GNAS 0 0 0 158 1 1
RIPK3 BPTF 0 0 0 276 1 1
RIPK3 DLG5 0 0 0 159 1 1
RIPK3 IL12RB2 0 0 0 221 1 1
RIPK3 CFD 0 0 0 174 1 1
RIPK3 DAPK3 0 0 74 185 1 2
RIPK3 KLRF1 0 0 0 152 1 1
RIPK3 FKBP1A 0 0 118 167 1 2
RIPK3 UBQLNL 0 0 0 152 1 1
RIPK3 PRF1 0 0 122 213 1 1
RIPK3 GLUD1 0 800 338 866 1 1
RIPK3 IL2RG 0 0 0 202 1 1
RIPK3 CD244 0 0 0 299 1 1
RIPK3 CISH 0 0 75 177 1 1
RIPK3 PTGER4 0 0 0 153 1 1
RIPK3 RPS6KB2 0 0 0 211 1 2
RIPK3 HSPA6 0 0 0 190 1 1
RIPK3 MFSD7 0 0 0 163 1 1
RIPK3 SPRED3 0 0 0 158 1 1
RIPK3 IFIH1 0 0 241 321 1 1
RIPK3 PAK2 0 0 0 156 1 1
RIPK3 CD79B 0 0 0 178 1 1
RIPK3 BCKDK 0 0 0 197 1 1
RIPK3 GRAPL 0 0 0 217 1 1
RIPK3 PYGM 0 800 0 809 1 1
RIPK3 ARG1 0 0 142 180 1 2
RIPK3 AURKB 0 0 58 196 1 1
RIPK3 SHANK2 0 0 0 161 1 1
RIPK3 TAX1BP1 0 0 143 173 1 2
RIPK3 UBD 0 0 96 172 1 1
RIPK3 SHANK1 0 0 0 161 1 1
RIPK3 STXBP6 0 0 81 496 1 1
RIPK3 EFNA5 0 0 0 168 1 1
RIPK3 MPEG1 0 0 0 286 1 1
RIPK3 ADAMDEC1 0 0 0 157 1 1
RIPK3 NCKAP1L 0 0 0 209 1 1
RIPK3 PPP3CC 0 0 0 158 1 1
RIPK3 DHX58 0 0 100 217 1 1
RIPK3 OSM 0 0 0 195 1 1
RIPK3 MFF 0 0 293 293 1 1
RIPK3 VASP 0 0 0 182 1 1
RIPK3 MAP2K1 0 0 66 193 1 1
RIPK3 PPIF 0 0 530 546 1 1
RIPK3 CD80 0 0 103 173 1 2
RIPK3 RBCK1 0 0 467 486 1 1
RIPK3 ENSG00000272772 0 0 0 196 1 1
RIPK3 UCK1 0 0 0 171 1 1
RIPK3 TLR1 0 0 157 355 1 1
RIPK3 NFE2L2 0 0 74 150 1 2
RIPK3 PGAM5 270 0 837 882 1 1
RIPK3 WDR62 0 0 0 185 1 1
RIPK3 MAP2K5 0 0 57 247 1 1
RIPK3 LILRA1 0 0 0 277 1 1
RIPK3 TREM1 0 0 0 185 1 1
RIPK3 CORO6 0 0 0 162 1 1
RIPK3 TAB2 0 0 425 470 1 2
RIPK3 GPSM3 0 0 66 268 1 1
RIPK3 IL18 0 0 457 472 1 2
RIPK3 IL1R1 0 0 204 243 1 1
RIPK3 RARRES3 0 0 57 178 1 1
RIPK3 CLECL1 0 0 0 168 1 1
RIPK3 IFITM3 0 0 66 165 1 1
RIPK3 ARL8B 0 0 0 151 1 1
RIPK3 PDK1 0 0 0 197 1 2
RIPK3 MYC 0 0 181 211 1 2
RIPK3 DGAT2L6 0 0 134 194 1 1
RIPK3 EFNA4 0 0 57 182 1 1
RIPK3 HSPBAP1 270 0 0 270 1 1
RIPK3 AMY1B 294 0 0 299 1 1
RIPK3 GNAT2 0 0 0 177 1 1
RIPK3 PLCB2 0 0 0 261 1 1
RIPK3 FBP2 0 0 172 178 1 1
RIPK3 PPP3CB 0 0 62 165 1 1
RIPK3 CD300A 0 0 0 242 1 1
RIPK3 DHX33 0 0 95 158 1 1
RIPK3 DENND1C 0 0 0 175 1 1
RIPK3 MYLK4 0 0 0 213 1 1
RIPK3 TRAF2 270 900 459 961 1 2
RIPK3 STOML1 0 0 72 481 1 1
RIPK3 TAB1 0 0 213 342 1 1
RIPK3 GNAT3 0 0 0 177 1 1
RIPK3 MX1 0 0 108 172 1 1
RIPK3 LY86 0 0 0 244 1 1
RIPK3 RPGR 0 0 0 159 1 1
RIPK3 SH3BP5 0 0 171 225 1 1
RIPK3 OXSR1 0 0 0 154 1 1
RIPK3 FGR 0 0 0 328 1 1
RIPK3 KDM7A 0 0 0 227 1 1
RIPK3 FCER2 0 0 0 161 1 1
RIPK3 RNF126 0 0 0 228 1 1
RIPK3 STAT3 0 0 193 297 1 2
RIPK3 TRIM23 0 0 47 174 1 1
RIPK3 CDK4 0 0 46 189 1 2
RIPK3 PSTPIP1 0 0 0 160 1 1
RIPK3 FES 0 0 0 187 1 1
RIPK3 MYD88 0 0 412 512 1 2
RIPK3 ADORA3 0 0 49 157 1 1
RIPK3 SARM1 0 0 500 499 1 1
RIPK3 ESX1 0 0 109 180 1 1
RIPK3 FADD 870 900 988 999 1 2
RIPK3 TTBK2 0 0 0 164 1 1
RIPK3 IRF9 0 0 125 183 1 1
RIPK3 LCP2 0 0 0 242 1 1
RIPK3 RASGRP2 0 0 0 203 1 1
RIPK3 PRKACG 0 0 0 200 1 1
RIPK3 PRKX 0 0 49 228 1 1
RIPK3 HSPBP1 0 0 139 174 1 1
RIPK3 SLMAP 0 0 0 239 1 1
RIPK3 DDIT3 0 0 156 176 1 2
RIPK3 SELPLG 0 0 66 233 1 1
RIPK3 RNF115 0 0 0 177 1 1
RIPK3 TRAF1 0 0 431 534 1 1
RIPK3 GZMH 0 0 48 295 1 1
RIPK3 GIMAP8 0 0 0 293 1 1
RIPK3 APOBEC3G 0 0 357 390 1 1
RIPK3 NLRP1 0 0 241 268 1 1
RIPK3 PTPN13 0 0 96 203 1 1
RIPK3 DENND2D 0 0 0 165 1 1
RIPK3 PTGS1 0 0 45 170 1 1
RIPK3 CD40LG 0 0 95 152 1 1
RIPK3 TRAF4 0 0 74 155 1 1
RIPK3 PIDD1 0 0 74 227 1 1
RIPK3 HELQ 270 0 0 286 1 1
RIPK3 TNFRSF1A 270 0 758 832 1 1
RIPK3 ACTN4 100 0 0 157 1 1
RIPK3 VPS4A 0 0 166 179 1 1
RIPK3 SECTM1 0 0 0 175 1 1
RIPK3 BRD2 0 0 45 226 1 1
RIPK3 LYZ 0 0 0 172 1 1
RIPK3 FRAT2 0 0 0 151 1 1
RIPK3 IL6 0 0 392 405 1 2
RIPK3 PPP1R12A 100 0 0 174 1 1
RIPK3 RAB12 0 0 66 203 1 2
RIPK3 MYSM1 0 0 72 170 1 1
RIPK3 MPO 0 0 207 282 1 2
RIPK3 GRIK3 0 0 0 150 1 1
RIPK3 STAB1 0 0 0 201 1 1
RIPK3 RNF11 0 0 107 203 1 1
RIPK3 KCNQ1 0 0 0 183 1 1
RIPK3 MAPK13 0 0 67 278 1 1
RIPK3 DOK7 0 0 0 175 1 1
RIPK3 CCT5 94 0 0 188 1 1
RIPK3 IL1B 0 0 556 663 1 2
RIPK3 TRPM7 0 0 336 336 1 1
RIPK3 HIF1A 0 0 184 208 1 2
RIPK3 OAS1 0 0 96 160 1 1
RIPK3 HCLS1 0 0 0 302 1 1
RIPK3 PYGL 157 800 436 901 1 1
RIPK3 TRAF5 0 0 403 546 1 1
RIPK3 TNFRSF1B 0 0 150 289 1 1
RIPK3 MS4A4A 0 0 0 181 1 1
RIPK3 ACSL5 0 0 0 215 1 1
RIPK3 SAMSN1 0 0 0 165 1 1
RIPK3 CXCR2 0 0 112 157 1 1
RIPK3 CSNK1G1 0 0 71 151 1 1
RIPK3 TMEM44 270 0 0 270 1 1
RIPK3 FCGR3A 0 0 66 245 1 1
RIPK3 MAP1LC3A 0 0 150 289 1 2
RIPK3 CDK2 0 0 82 187 1 2
RIPK3 MYO1D 118 0 0 160 1 1
RIPK3 BCL2L1 0 0 446 454 1 2
RIPK3 LONRF2 0 0 0 200 1 1
RIPK3 CLEC7A 0 0 170 215 1 1
RIPK3 TAB3 0 0 297 395 1 1
RIPK3 PIK3R4 0 0 108 176 1 2
RIPK3 NF1 0 0 47 160 1 1
RIPK3 CLIC6 0 0 0 150 1 1
RIPK3 CD14 0 600 0 670 1 1
RIPK3 GAPT 0 0 0 207 1 1
RIPK3 GABARAPL2 0 0 150 204 1 2
RIPK3 ATG14 0 0 181 201 1 2
RIPK3 TNFRSF25 0 0 235 252 1 1
RIPK3 CDK10 0 0 0 154 1 1
RIPK3 TLR4 0 600 508 831 1 2
RIPK3 CCL5 0 0 181 236 1 2
RIPK3 HCST 0 0 0 214 1 1
RIPK3 BIRC2 270 900 663 976 1 1
RIPK3 IFNG 0 0 134 216 1 2
RIPK3 HSPA1L 106 0 0 194 1 1
RIPK3 MAPK4 0 0 0 164 1 1
RIPK3 PRKACA 0 0 0 193 1 1
RIPK3 HAVCR1 0 0 143 153 1 1
RIPK3 GSDMA 0 0 404 404 1 1
RIPK3 MAPKBP1 0 0 0 185 1 1
RIPK3 PDP2 0 0 0 201 1 1
RIPK3 LGALS9 0 0 0 316 1 1
RIPK3 SPECC1L 105 0 0 161 1 1
RIPK3 CACNA2D4 0 0 0 161 1 1
RIPK3 ANXA5 0 0 456 466 1 2
Ontologies
ID Category Term Effect Evidence PubMed
GO:0005524 Molecular Function ATP binding enables IEA
GO:0042802 Molecular Function identical protein binding enables IPI
GO:0005515 Molecular Function protein binding enables IPI
GO:0004672 Molecular Function protein kinase activity enables IBA
GO:0004672 Molecular Function protein kinase activity enables IDA
GO:0004672 Molecular Function protein kinase activity enables IMP
GO:0106310 Molecular Function protein serine kinase activity enables IEA
GO:0004674 Molecular Function protein serine/threonine kinase activity enables IDA
GO:0004674 Molecular Function protein serine/threonine kinase activity enables ISS
GO:0004674 Molecular Function protein serine/threonine kinase activity enables TAS
GO:0044877 Molecular Function protein-containing complex binding enables IMP
GO:0003713 Molecular Function transcription coactivator activity enables TAS
GO:0033077 Biological Process T cell differentiation in thymus involved_in ISS
GO:0043029 Biological Process T cell homeostasis involved_in ISS
GO:0032147 Biological Process activation of protein kinase activity involved_in IMP
GO:1990000 Biological Process amyloid fibril formation involved_in IMP
GO:0097190 Biological Process apoptotic signaling pathway involved_in TAS
GO:0007249 Biological Process canonical NF-kappaB signal transduction involved_in IEA
GO:0070301 Biological Process cellular response to hydrogen peroxide involved_in ISS
GO:0051607 Biological Process defense response to virus involved_in ISS
GO:0097528 Biological Process execution phase of necroptosis involved_in ISS
GO:0048535 Biological Process lymph node development involved_in ISS
GO:0070266 Biological Process necroptotic process involved_in IMP
GO:0070266 Biological Process necroptotic process involved_in TAS
GO:0097527 Biological Process necroptotic signaling pathway involved_in IDA
GO:0097527 Biological Process necroptotic signaling pathway involved_in IMP
GO:0045893 Biological Process positive regulation of DNA-templated transcription involved_in IEA
GO:0051092 Biological Process positive regulation of NF-kappaB transcription factor activity involved_in IDA
GO:0043123 Biological Process positive regulation of canonical NF-kappaB signal transduction involved_in IEA
GO:2001244 Biological Process positive regulation of intrinsic apoptotic signaling pathway involved_in IEA
GO:0060545 Biological Process positive regulation of necroptotic process involved_in IDA
GO:0060545 Biological Process positive regulation of necroptotic process involved_in IMP
GO:0010922 Biological Process positive regulation of phosphatase activity involved_in IMP
GO:2000379 Biological Process positive regulation of reactive oxygen species metabolic process involved_in IEA
GO:0097300 Biological Process programmed necrotic cell death involved_in ISS
GO:0046777 Biological Process protein autophosphorylation involved_in IDA
GO:0036211 Biological Process protein modification process involved_in TAS
GO:0072593 Biological Process reactive oxygen species metabolic process involved_in IEA
GO:2000452 Biological Process regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation involved_in ISS
GO:0001914 Biological Process regulation of T cell mediated cytotoxicity involved_in ISS
GO:0046006 Biological Process regulation of activated T cell proliferation involved_in ISS
GO:0070235 Biological Process regulation of activation-induced cell death of T cells involved_in ISS
GO:0002819 Biological Process regulation of adaptive immune response involved_in ISS
GO:0042981 Biological Process regulation of apoptotic process involved_in ISS
GO:0032649 Biological Process regulation of type II interferon production involved_in ISS
GO:0007165 Biological Process signal transduction involved_in IBA
GO:0048536 Biological Process spleen development involved_in ISS
GO:0048538 Biological Process thymus development involved_in ISS
GO:0005737 Cellular Component cytoplasm is_active_in IBA
GO:0005829 Cellular Component cytosol located_in IDA
GO:0005829 Cellular Component cytosol located_in TAS
GO:0005634 Cellular Component nucleus is_active_in IDA
GO:0005634 Cellular Component nucleus located_in ISS
GO:0032991 Cellular Component protein-containing complex part_of IDA
Pathways
Name DB ID
ZBP1(DAI) mediated induction of type I IFNs Reactome R-HSA-1606322
Disease Reactome R-HSA-1643685
Toll Like Receptor 4 (TLR4) Cascade Reactome R-HSA-166016
MyD88-independent TLR4 cascade Reactome R-HSA-166166
Toll Like Receptor 3 (TLR3) Cascade Reactome R-HSA-168164
Innate Immune System Reactome R-HSA-168249
Immune System Reactome R-HSA-168256
Toll-like Receptor Cascades Reactome R-HSA-168898
TICAM1, RIP1-mediated IKK complex recruitment Reactome R-HSA-168927
RIP-mediated NFkB activation via ZBP1 Reactome R-HSA-1810476
Cytosolic sensors of pathogen-associated DNA Reactome R-HSA-1834949
TRIF-mediated programmed cell death Reactome R-HSA-2562578
Stimuli-sensing channels Reactome R-HSA-2672351
TRP channels Reactome R-HSA-3295583
Transport of small molecules Reactome R-HSA-382551
RIPK1-mediated regulated necrosis Reactome R-HSA-5213460
Regulated Necrosis Reactome R-HSA-5218859
Programmed Cell Death Reactome R-HSA-5357801
Infectious disease Reactome R-HSA-5663205
Regulation of necroptotic cell death Reactome R-HSA-5675482
TLR3-mediated TICAM1-dependent programmed cell death Reactome R-HSA-9013957
IKK complex recruitment mediated by RIP1 Reactome R-HSA-937041
TRIF(TICAM1)-mediated TLR4 signaling Reactome R-HSA-937061
Diseases of programmed cell death Reactome R-HSA-9645723
SARS-CoV-1 Infection Reactome R-HSA-9678108
SARS-CoV Infections Reactome R-HSA-9679506
Microbial modulation of RIPK1-mediated regulated necrosis Reactome R-HSA-9686347
SARS-CoV-1-mediated effects on programmed cell death Reactome R-HSA-9692913
SARS-CoV-1-host interactions Reactome R-HSA-9692914
SARS-CoV-1 activates/modulates innate immune responses Reactome R-HSA-9692916
Defective RIPK1-mediated regulated necrosis Reactome R-HSA-9693928
Viral Infection Pathways Reactome R-HSA-9824446
Ion channel transport Reactome R-HSA-983712
Pro-survival signaling of neuroprotectin D1 (WP5182) WikiPathways WP5182_r122168
Cytosolic DNA-sensing pathway (WP4655) WikiPathways WP4655_r123496
TNF-alpha signaling pathway (WP231) WikiPathways WP231_r124583
Nanoparticle triggered regulated necrosis (WP2513) WikiPathways WP2513_r119820
Transcripts
Accession Version MolecularType Name NCBI Comments
NM_006871 4 mRNA None NC_000014 Reference