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COL2A1

collagen type II alpha 1 chain
General Information
Name collagen type II alpha 1 chain
Alias
  • collagen alpha-1(II) chain
  • alpha-1 type II collagen
  • arthroophthalmopathy, progressive (Stickler syndrome)
  • cartilage collagen
  • chondrocalcin
  • collagen II, alpha-1 polypeptide
  • collagen, type II, alpha 1
Gene_family Collagens
organism Homo sapiens
entrez_id 1280
location 12q13.11
transcript_count 7
exon_count 57
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. [provided by RefSeq, Jul 2008]
    Stringdb Collagen alpha-1(II) chain; Type II collagen is specific for cartilaginous tissues. It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces
    nextProt Type II collagen is specific for cartilaginous tissues. It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces.
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
COL2A1 BioGRID USP48 GeneID BioGRID Affinity Capture-MS
COL2A1 BioGRID RAF1 GeneID BioGRID Affinity Capture-MS
COL2A1 BioGRID C1QTNF9B GeneID BioGRID Affinity Capture-MS
COL2A1 BioGRID C1QTNF9 GeneID BioGRID Affinity Capture-MS
COL2A1 BioGRID CHODL GeneID BioGRID Affinity Capture-MS
COL2A1 BioGRID OSCAR GeneID BioGRID Affinity Capture-MS
COL2A1 BioGRID C1QTNF2 GeneID BioGRID Affinity Capture-MS
COL2A1 BioGRID C1QTNF1 GeneID BioGRID Affinity Capture-MS
COL2A1 BioGRID COLGALT2 GeneID BioGRID Affinity Capture-MS
COL2A1 BioGRID FKBP9 GeneID BioGRID Affinity Capture-MS
COL2A1 BioGRID NXPH2 GeneID BioGRID Affinity Capture-MS
COL2A1 BioGRID CNPY2 GeneID BioGRID Affinity Capture-MS
COL2A1 BioGRID RPL36AL GeneID BioGRID Affinity Capture-MS
COL2A1 BioGRID PLOD1 GeneID BioGRID Affinity Capture-MS
COL2A1 BioGRID P4HA1 GeneID BioGRID Affinity Capture-MS
COL2A1 BioGRID MMP9 GeneID BioGRID Affinity Capture-MS
COL2A1 BioGRID MMP2 GeneID BioGRID Affinity Capture-MS
COL2A1 BioGRID LAIR2 GeneID BioGRID Affinity Capture-MS
COL2A1 BioGRID COL9A1 GeneID BioGRID Affinity Capture-MS; Reconstituted Complex
COL2A1 BioGRID COL8A2 GeneID BioGRID Affinity Capture-MS
COL2A1 BioGRID COL8A1 GeneID BioGRID Affinity Capture-MS
COL2A1 BioGRID C1QC GeneID BioGRID Affinity Capture-MS
COL2A1 BioGRID KEAP1 GeneID BioGRID Two-hybrid
COL2A1 BioGRID AGR2 GeneID BioGRID Proximity Label-MS
COL2A1 BioGRID PDGFB GeneID BioGRID Far Western; Reconstituted Complex
COL2A1 BioGRID PDGFA GeneID BioGRID Reconstituted Complex
COL2A1 BioGRID PDIA2 GeneID BioGRID Reconstituted Complex
COL2A1 BioGRID RELA GeneID BioGRID Two-hybrid
COL2A1 BioGRID HYAL1 GeneID BioGRID Two-hybrid
COL2A1 Protein SPARC GeneID HPRD
COL2A1 Protein LOXL4 GeneID HPRD
COL2A1 Protein ITGA2B GeneID HPRD
COL2A1 Protein TNFRSF10A GeneID HPRD
COL2A1 Protein HTRA1 GeneID HPRD
COL2A1 Protein CHAD GeneID HPRD
COL2A1 Protein PRELP GeneID HPRD
COL2A1 Protein TGFBI GeneID HPRD
COL2A1 Protein PKD1 GeneID HPRD
COL2A1 Protein DDR1 GeneID HPRD
COL2A1 Protein COMP GeneID HPRD
COL2A1 Protein PCOLCE GeneID HPRD
COL2A1 Protein MMP13 GeneID HPRD
COL2A1 Protein BGN GeneID HPRD
COL2A1 Protein TGFB1 GeneID HPRD
COL2A1 Protein THBS1 GeneID HPRD
COL2A1 Protein FGF7 GeneID HPRD
COL2A1 Protein FN1 GeneID HPRD
COL2A1 Protein ANXA5 GeneID HPRD
COL2A1 Protein C1QA GeneID HPRD
COL2A1 Protein MMP1 GeneID HPRD
COL2A1 Protein COL9A3 GeneID HPRD
COL2A1 Protein COL9A2 GeneID HPRD
COL2A1 Protein COL6A1 GeneID HPRD
COL2A1 Protein COL2A1 GeneID HPRD
COL2A1 Protein MATN1 GeneID HPRD
COL2A1 Protein BMP2 GeneID HPRD
COL2A1 Protein MAG GeneID HPRD
COL2A1 BioGRID PKD1 GeneID BioGRID Reconstituted Complex
COL2A1 BioGRID THBS1 GeneID BioGRID Reconstituted Complex
COL2A1 BioGRID TGFB1 GeneID BioGRID Reconstituted Complex
COL2A1 BioGRID PRELP GeneID BioGRID Reconstituted Complex
COL2A1 BioGRID MAG GeneID BioGRID Reconstituted Complex
COL2A1 BioGRID ITGA2B GeneID BioGRID Reconstituted Complex
COL2A1 BioGRID ANXA5 GeneID BioGRID Reconstituted Complex
COL2A1 BioGRID BMP2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
COL2A1 BioGRID Igfbp7 GeneID BioGRID Affinity Capture-Western
COL2A1 Protein None None BIND Col-2 interacts with alpha-2-beta-1 integrin. This interaction was modeled on a demonstrated interaction between chicken Col-2 and human alpha-2-beta-1 integrin.
StringDB
A B experiments database textmining combined score hadb nhadb
COL2A1 ISL1 0 0 208 220 1 1
COL2A1 POSTN 0 0 324 386 1 1
COL2A1 FZD4 0 0 134 292 1 1
COL2A1 HIF3A 0 0 136 160 1 1
COL2A1 DLX4 0 0 122 166 1 1
COL2A1 CXCL8 0 0 233 232 1 2
COL2A1 WNT7A 0 0 203 209 1 1
COL2A1 PAX2 0 0 112 159 1 1
COL2A1 CTNNB1 0 0 469 557 1 2
COL2A1 HRAS 0 0 125 185 1 2
COL2A1 MYF5 0 0 180 179 1 1
COL2A1 EGR1 0 0 213 226 1 2
COL2A1 WNT2B 0 0 162 219 1 1
COL2A1 DDR2 0 0 473 522 1 1
COL2A1 CXCR4 0 0 138 184 1 2
COL2A1 CYR61 0 0 150 199 1 1
COL2A1 MMP1 213 0 468 579 1 1
COL2A1 MTOR 0 0 123 156 1 2
COL2A1 MAN1B1 0 0 288 288 1 1
COL2A1 ACAN 0 0 879 448 1 1
COL2A1 STAT1 0 0 124 376 1 2
COL2A1 COL27A1 0 360 460 473 1 1
COL2A1 COL24A1 0 300 325 391 1 1
COL2A1 CILP 0 0 391 390 1 1
COL2A1 SDHB 0 0 151 157 1 1
COL2A1 RSPO2 0 0 169 201 1 1
COL2A1 FRAS1 0 0 74 164 1 1
COL2A1 PANX3 0 0 113 183 1 1
COL2A1 CREBBP 0 0 137 197 1 1
COL2A1 CREB1 0 0 183 200 1 2
COL2A1 CTNND1 0 0 59 269 1 1
COL2A1 C1QTNF9B 0 0 46 163 1 1
COL2A1 COL25A1 0 300 217 428 1 1
COL2A1 SIRT2 0 0 274 282 1 2
COL2A1 WNT11 0 0 254 279 1 1
COL2A1 WIF1 0 0 140 197 1 1
COL2A1 MMP20 0 0 108 317 1 1
COL2A1 ITGA4 0 600 81 649 1 1
COL2A1 NFKB1 0 0 109 164 1 2
COL2A1 RELA 111 0 134 197 1 2
COL2A1 MFAP2 0 0 166 230 1 1
COL2A1 FGFR2 0 0 310 376 1 1
COL2A1 HEYL 0 0 139 157 1 1
COL2A1 GREM1 0 0 255 306 1 1
COL2A1 GAPDH 0 0 604 624 1 2
COL2A1 TCF7L2 0 0 59 191 1 1
COL2A1 ALPI 0 0 150 181 1 1
COL2A1 TMEM106C 0 0 150 235 1 1
COL2A1 MAP2K7 0 0 124 282 1 1
COL2A1 PLCL1 0 0 95 264 1 1
COL2A1 MATN2 0 0 213 318 1 1
COL2A1 SOX11 0 0 257 291 1 1
COL2A1 LAMA5 0 0 66 331 1 1
COL2A1 ILK 0 0 82 203 1 1
COL2A1 WNT5A 0 0 341 378 1 2
COL2A1 KIF21A 0 0 137 169 1 1
COL2A1 IBSP 0 0 557 593 1 1
COL2A1 P4HB 0 600 134 652 1 2
COL2A1 TBX5 0 0 163 194 1 1
COL2A1 DVL1 0 0 135 185 1 1
COL2A1 CELA1 0 0 389 388 1 1
COL2A1 ACP5 0 0 325 336 1 1
COL2A1 FLNA 0 0 157 199 1 1
COL2A1 LRP5 0 0 310 340 1 1
COL2A1 ITFG2 0 0 69 171 1 1
COL2A1 DLX2 0 0 169 308 1 1
COL2A1 SPARCL1 0 0 0 197 1 1
COL2A1 INHBA 0 0 120 174 1 1
COL2A1 TEX28 0 0 66 164 1 1
COL2A1 ACTA1 0 0 155 195 1 1
COL2A1 CYTL1 0 0 218 218 1 1
COL2A1 OGN 0 0 261 305 1 1
COL2A1 PITX1 0 0 155 202 1 1
COL2A1 PDGFB 297 0 89 332 1 2
COL2A1 PAX9 0 0 265 283 1 1
COL2A1 SEC24C 0 0 67 175 1 1
COL2A1 TOP2A 0 0 67 203 1 1
COL2A1 FZD2 0 0 134 195 1 1
COL2A1 TP53 0 0 261 261 1 2
COL2A1 HOXA13 0 0 182 227 1 1
COL2A1 DCN 0 0 491 539 1 2
COL2A1 MAOA 0 0 0 157 1 1
COL2A1 B4GALT7 0 0 184 211 1 1
COL2A1 INSIG1 0 0 81 223 1 1
COL2A1 SHOX 0 0 264 307 1 1
COL2A1 FLNB 0 0 164 206 1 1
COL2A1 SATB2 0 0 181 196 1 1
COL2A1 FGFR3 43 0 507 569 1 1
COL2A1 SLC2A1 0 0 138 176 1 2
COL2A1 EGFR 0 0 144 220 1 2
COL2A1 ECM1 0 0 171 171 1 1
COL2A1 CRYGB 0 0 48 154 1 1
COL2A1 LMX1B 0 0 73 186 1 1
COL2A1 COL23A1 0 300 244 404 1 1
COL2A1 ADAMTS1 0 0 265 441 1 1
COL2A1 HAND1 0 0 181 206 1 1
COL2A1 HDAC2 0 0 225 234 1 1
COL2A1 HNRNPA1L2 0 0 0 158 1 1
COL2A1 WNT4 0 0 248 290 1 1
COL2A1 TNFRSF11B 0 0 310 353 1 1
COL2A1 LAMA4 0 0 123 247 1 1
COL2A1 PAEP 0 0 155 154 1 1
COL2A1 CDH2 0 0 285 334 1 1
COL2A1 GNAT1 0 0 112 192 1 1
COL2A1 CALM3 0 0 325 336 1 1
COL2A1 CLU 0 0 139 157 1 2
COL2A1 CHST11 0 0 242 243 1 1
COL2A1 VIT 0 0 183 205 1 1
COL2A1 ITGA5 0 600 243 711 1 1
COL2A1 MMP15 0 0 154 339 1 1
COL2A1 KRT5 0 0 81 163 1 1
COL2A1 PRKAR2A 0 0 0 159 1 1
COL2A1 MYH6 0 0 159 211 1 1
COL2A1 SERPINH1 0 600 343 780 1 1
COL2A1 SOX4 0 0 155 203 1 1
COL2A1 PTN 0 0 181 199 1 1
COL2A1 ETNK1 0 0 389 388 1 1
COL2A1 ITGB8 0 600 83 633 1 1
COL2A1 SNAI2 0 0 219 247 1 1
COL2A1 CCL2 0 0 180 179 1 2
COL2A1 ALB 0 0 369 419 1 2
COL2A1 CAPN6 0 0 81 210 1 1
COL2A1 CLEC3A 0 0 185 208 1 1
COL2A1 ADAMTS6 0 0 113 206 1 1
COL2A1 LARP6 0 0 0 181 1 1
COL2A1 THBS4 0 0 321 349 1 1
COL2A1 LEF1 0 0 301 318 1 1
COL2A1 PRTG 0 0 108 270 1 1
COL2A1 PDGFRB 0 0 143 199 1 2
COL2A1 EP300 0 0 244 255 1 2
COL2A1 DPT 0 0 155 175 1 1
COL2A1 WNT9B 0 0 163 250 1 1
COL2A1 SMAD3 0 0 390 473 1 2
COL2A1 SOX15 0 0 124 156 1 1
COL2A1 SPARC 213 0 391 709 1 2
COL2A1 HOXA2 0 0 252 263 1 1
COL2A1 SERPINF1 0 0 180 350 1 1
COL2A1 ROCK1 0 0 85 179 1 2
COL2A1 KCNIP3 0 0 0 158 1 1
COL2A1 ACTC1 0 0 208 309 1 1
COL2A1 WNT16 0 0 245 271 1 1
COL2A1 COL20A1 0 300 175 351 1 1
COL2A1 BUB1B 0 0 49 160 1 1
COL2A1 PDGFRA 0 0 150 227 1 1
COL2A1 ALCAM 0 0 325 340 1 1
COL2A1 CDH1 0 0 142 155 1 2
COL2A1 IDH1 0 0 164 163 1 1
COL2A1 C21orf2 0 0 0 165 1 1
COL2A1 LOXL2 0 0 141 235 1 1
COL2A1 COPS3 0 0 49 194 1 1
COL2A1 ACVR2B 0 0 91 162 1 1
COL2A1 MRPS7 0 0 0 365 1 1
COL2A1 ROCK2 0 0 57 154 1 1
COL2A1 PAX6 0 0 246 324 1 1
COL2A1 WNT1 0 0 285 407 1 2
COL2A1 CHSY1 0 0 163 187 1 1
COL2A1 MMP16 0 0 169 333 1 1
COL2A1 EFEMP2 0 0 214 333 1 1
COL2A1 COL4A1 0 300 424 539 1 1
COL2A1 PTK2 0 600 96 654 1 2
COL2A1 FRZB 0 0 426 451 1 1
COL2A1 BMP1 0 900 294 930 1 1
COL2A1 PHOSPHO1 0 0 245 310 1 1
COL2A1 CALCA 0 0 117 203 1 1
COL2A1 FGF18 0 0 364 394 1 1
COL2A1 BOC 0 0 53 182 1 1
COL2A1 ITGA7 0 600 47 636 1 1
COL2A1 COLGALT1 0 600 0 600 1 1
COL2A1 GP6 0 600 48 602 1 1
COL2A1 VCAN 0 0 467 478 1 1
COL2A1 RAC3 0 0 0 182 1 2
COL2A1 CHAD 213 0 469 596 1 1
COL2A1 BMP2 270 0 611 786 1 1
COL2A1 UCMA 0 0 213 262 1 1
COL2A1 EGF 0 0 218 218 1 2
COL2A1 HAS1 0 0 210 210 1 1
COL2A1 OTOR 0 0 165 242 1 1
COL2A1 C1QTNF2 274 0 0 407 1 1
COL2A1 SLC26A2 0 0 420 420 1 1
COL2A1 GATA4 0 0 181 258 1 2
COL2A1 DICER1 0 0 166 182 1 1
COL2A1 LHX8 0 0 122 158 1 1
COL2A1 COL4A4 0 300 323 503 1 1
COL2A1 HSP90B1 0 0 119 163 1 1
COL2A1 TEK 0 0 125 222 1 1
COL2A1 LPL 0 0 246 246 1 1
COL2A1 CDH17 0 0 150 163 1 1
COL2A1 DOK4 0 0 46 186 1 1
COL2A1 XYLT1 0 0 294 403 1 1
COL2A1 COL16A1 0 300 346 652 1 1
COL2A1 JUN 0 0 243 295 1 2
COL2A1 ASF1A 0 0 308 337 1 1
COL2A1 PXDN 0 0 53 280 1 1
COL2A1 MKX 0 0 307 337 1 1
COL2A1 FZD1 0 0 184 217 1 1
COL2A1 RERE 0 0 306 306 1 1
COL2A1 DNTT 0 0 228 237 1 1
COL2A1 ARID5B 0 0 150 168 1 1
COL2A1 CCNA2 0 0 134 174 1 1
COL2A1 COL18A1 0 300 229 410 1 1
COL2A1 ERBB4 0 0 48 169 1 1
COL2A1 ZBTB16 0 0 66 177 1 1
COL2A1 SMAD1 0 0 75 318 1 2
COL2A1 CHST3 0 0 156 155 1 1
COL2A1 BMP6 0 0 424 501 1 1
COL2A1 NFATC3 0 0 90 254 1 1
COL2A1 KRT8 0 0 171 197 1 1
COL2A1 COL3A1 0 720 653 746 1 1
COL2A1 RUNX3 0 0 266 266 1 1
COL2A1 EYS 0 0 0 191 1 1
COL2A1 CREB3L2 0 0 190 240 1 1
COL2A1 ITGA10 0 900 244 924 1 1
COL2A1 FST 0 0 120 190 1 1
COL2A1 JAG1 0 0 226 293 1 1
COL2A1 ASB16 0 0 103 208 1 1
COL2A1 CHADL 0 0 193 222 1 1
COL2A1 SOX17 0 0 147 180 1 1
COL2A1 SULF1 0 0 159 178 1 1
COL2A1 COMP 213 0 638 752 1 1
COL2A1 SOST 0 0 324 378 1 1
COL2A1 PRG4 0 0 602 650 1 1
COL2A1 OMD 0 0 290 315 1 1
COL2A1 PTPRC 0 0 322 340 1 1
COL2A1 MIXL1 0 0 180 211 1 1
COL2A1 GDF3 0 0 150 207 1 1
COL2A1 ITGAV 0 900 171 920 1 1
COL2A1 CCNB2 0 0 124 185 1 1
COL2A1 SOX9 0 0 870 908 1 1
COL2A1 SOX8 0 0 391 456 1 1
COL2A1 SPP1 0 0 556 587 1 2
COL2A1 TIMP1 0 0 415 427 1 1
COL2A1 FGF1 0 0 211 304 1 1
COL2A1 EMR2 0 0 0 173 1 1
COL2A1 SLC11A2 0 0 0 163 1 1
COL2A1 MMP9 130 0 465 536 1 2
COL2A1 MAPK3 0 0 261 314 1 2
COL2A1 THY1 0 0 450 450 1 1
COL2A1 HDAC4 0 0 283 288 1 2
COL2A1 PRRX1 0 0 283 342 1 1
COL2A1 COL14A1 0 300 369 514 1 1
COL2A1 ABCA4 0 0 112 152 1 1
COL2A1 SOX2 0 0 339 394 1 2
COL2A1 CHRM1 0 0 0 161 1 1
COL2A1 ZNF789 0 0 91 350 1 1
COL2A1 KDR 0 0 141 203 1 2
COL2A1 DMP1 0 0 154 284 1 1
COL2A1 RAC2 0 0 0 158 1 1
COL2A1 ASPN 0 0 466 496 1 1
COL2A1 HYAL1 111 0 128 317 1 1
COL2A1 IRX6 0 0 97 173 1 1
COL2A1 TRPV4 0 0 267 275 1 1
COL2A1 CNN1 0 0 172 178 1 1
COL2A1 MMP10 0 0 202 352 1 1
COL2A1 LUM 0 720 415 859 1 1
COL2A1 KRT19 0 0 247 280 1 1
COL2A1 TGFB1 270 0 393 654 1 2
COL2A1 CDC42 0 0 123 236 1 2
COL2A1 TLL2 0 900 0 905 1 1
COL2A1 DKK1 0 0 294 315 1 1
COL2A1 ADAMTS17 0 0 151 255 1 1
COL2A1 PDGFRL 0 0 81 162 1 1
COL2A1 FOXO3 0 0 124 178 1 2
COL2A1 ITGA6 0 600 143 672 1 1
COL2A1 BGLAP 0 0 680 687 1 1
COL2A1 TNFSF11 0 0 383 444 1 2
COL2A1 PLOD3 0 600 64 677 1 1
COL2A1 TNPO2 0 0 0 213 1 1
COL2A1 ELTD1 0 0 66 160 1 1
COL2A1 HNF4A 0 0 229 239 1 1
COL2A1 ADAMTS18 0 0 92 238 1 1
COL2A1 DTD1 0 0 0 192 1 1
COL2A1 COL28A1 0 300 123 405 1 1
COL2A1 LPAR1 0 0 324 323 1 1
COL2A1 KRT18 0 0 181 198 1 1
COL2A1 MAG 270 0 0 348 1 1
COL2A1 EFEMP1 0 0 155 283 1 1
COL2A1 GJA1 0 0 150 170 1 1
COL2A1 ZNF449 0 0 108 151 1 1
COL2A1 BMP8B 0 0 63 157 1 1
COL2A1 NID2 0 0 150 366 1 1
COL2A1 AGO3 0 0 0 190 1 1
COL2A1 CD34 0 0 323 355 1 2
COL2A1 NGF 0 0 167 167 1 2
COL2A1 DDR1 213 0 436 580 1 1
COL2A1 FOXF1 0 0 282 283 1 1
COL2A1 FBN1 0 0 392 473 1 1
COL2A1 CRTAP 0 600 249 705 1 1
COL2A1 ZNF521 0 0 0 193 1 1
COL2A1 CYP2J2 0 0 0 214 1 1
COL2A1 TGFBI 213 0 223 417 1 1
COL2A1 AIFM1 0 0 96 161 1 1
COL2A1 VCAM1 0 0 213 222 1 1
COL2A1 MEPE 0 0 112 272 1 1
COL2A1 CLPP 0 0 61 160 1 1
COL2A1 FBN2 0 0 232 367 1 1
COL2A1 FBN3 0 0 74 257 1 1
COL2A1 COL4A3 0 300 208 417 1 1
COL2A1 PCOLCE2 0 900 67 904 1 1
COL2A1 GDF7 0 0 175 210 1 1
COL2A1 TGIF1 0 0 113 221 1 1
COL2A1 COL4A2 0 300 324 525 1 1
COL2A1 DKK3 0 0 155 154 1 1
COL2A1 TJP2 0 0 0 189 1 1
COL2A1 ADAMTS4 0 0 684 709 1 1
COL2A1 CD44 0 600 405 762 1 2
COL2A1 SIX1 0 0 167 173 1 1
COL2A1 COL8A1 0 300 391 461 1 1
COL2A1 NOV 0 0 166 165 1 1
COL2A1 ADAMTS9 0 0 142 247 1 1
COL2A1 CELF1 0 0 55 165 1 1
COL2A1 EYA1 0 0 384 397 1 1
COL2A1 OTOL1 0 0 0 201 1 1
COL2A1 IFT140 0 0 90 209 1 1
COL2A1 DDX3X 0 0 0 213 1 1
COL2A1 ACVR2A 0 0 134 164 1 1
COL2A1 MMP7 0 0 193 344 1 1
COL2A1 COL8A2 641 300 158 781 1 1
COL2A1 VCL 0 0 134 247 1 1
COL2A1 SFRP4 0 0 150 156 1 1
COL2A1 FGF2 0 0 459 479 1 2
COL2A1 CXCL3 0 0 181 181 1 1
COL2A1 COL26A1 0 300 166 390 1 1
COL2A1 AXIN2 0 0 263 279 1 1
COL2A1 PLXNB2 0 0 0 208 1 1
COL2A1 PTCH1 0 0 367 402 1 1
COL2A1 TNNT2 0 0 139 310 1 1
COL2A1 VWF 0 0 209 244 1 1
COL2A1 SOX5 0 0 689 755 1 1
COL2A1 IFNAR1 0 0 0 212 1 1
COL2A1 TNFAIP6 0 0 350 360 1 1
COL2A1 ITGA3 0 600 193 692 1 2
COL2A1 IGF1 0 0 501 501 1 2
COL2A1 TNMD 0 0 504 531 1 1
COL2A1 APOB 0 0 120 150 1 2
COL2A1 SHOX2 0 0 218 264 1 1
COL2A1 SDC4 0 600 155 651 1 1
COL2A1 SPAM1 0 0 81 281 1 1
COL2A1 HIVEP1 0 0 204 227 1 1
COL2A1 CRLF1 0 0 146 152 1 1
COL2A1 HEY1 0 0 202 207 1 1
COL2A1 PRRX2 0 0 97 224 1 1
COL2A1 ACTA2 0 0 242 304 1 1
COL2A1 LOXL1 0 0 232 301 1 1
COL2A1 FLI1 0 0 0 154 1 1
COL2A1 CCND1 0 0 250 250 1 2
COL2A1 FSHR 0 0 0 195 1 1
COL2A1 FGF5 0 0 81 151 1 1
COL2A1 WNT9A 0 0 294 367 1 1
COL2A1 ATP5F1 0 0 57 203 1 1
COL2A1 MYL2 0 0 97 173 1 1
COL2A1 PSPC1 0 0 277 277 1 1
COL2A1 NCF1 0 0 360 368 1 1
COL2A1 ALPL 0 0 595 626 1 1
COL2A1 MDK 0 0 45 181 1 1
COL2A1 SCX 0 0 325 448 1 1
COL2A1 RHEB 0 0 0 153 1 2
COL2A1 KIF23 0 0 0 165 1 1
COL2A1 COLEC11 0 0 0 206 1 1
COL2A1 TRPS1 0 0 269 279 1 1
COL2A1 COL7A1 0 300 282 399 1 1
COL2A1 RUNX1 0 0 0 252 1 2
COL2A1 COL6A3 0 300 400 436 1 1
COL2A1 PECAM1 0 0 263 296 1 1
COL2A1 SPINK1 0 0 54 181 1 1
COL2A1 NKX2-5 0 0 150 219 1 1
COL2A1 PTK2B 0 0 74 197 1 1
COL2A1 THSD4 0 0 46 180 1 1
COL2A1 LRP6 0 0 161 185 1 1
COL2A1 BMP5 0 0 261 374 1 1
COL2A1 FSTL1 0 0 489 574 1 1
COL2A1 HAPLN1 0 0 556 561 1 1
COL2A1 EDIL3 0 0 57 157 1 1
COL2A1 COLEC10 0 0 0 211 1 1
COL2A1 MYOD1 0 0 269 308 1 1
COL2A1 HOXD9 0 0 97 210 1 1
COL2A1 PRELP 270 0 371 543 1 1
COL2A1 COL10A1 0 300 870 528 1 1
COL2A1 NFIA 0 0 70 281 1 1
COL2A1 VEGFA 0 0 391 390 1 2
COL2A1 PTEN 0 0 172 230 1 2
COL2A1 TIMP3 0 0 325 372 1 1
COL2A1 MEOX2 0 0 166 204 1 1
COL2A1 ENSG00000258947 0 0 151 204 1 1
COL2A1 WSB2 0 0 74 159 1 1
COL2A1 PTH1R 0 0 491 544 1 1
COL2A1 KERA 0 0 113 198 1 1
COL2A1 CD164 0 0 67 166 1 1
COL2A1 RIMS1 0 0 0 162 1 1
COL2A1 BMP4 0 0 468 615 1 1
COL2A1 LEP 0 0 195 202 1 1
COL2A1 NFKBIA 0 0 195 209 1 2
COL2A1 PRKG2 0 0 499 507 1 1
COL2A1 COL17A1 0 300 161 355 1 1
COL2A1 SEMA3E 0 0 0 183 1 1
COL2A1 AXIN1 0 0 146 180 1 1
COL2A1 RPL37 0 0 43 173 1 1
COL2A1 LEPREL1 0 600 218 694 1 1
COL2A1 ITGA2B 462 600 57 783 1 1
COL2A1 SMAD5 0 0 243 351 1 1
COL2A1 SFRP1 0 0 183 216 1 1
COL2A1 SDC3 0 0 150 191 1 1
COL2A1 RBPJ 0 0 212 289 1 1
COL2A1 COL1A1 43 720 827 743 1 2
COL2A1 ITGB4 0 600 66 639 1 1
COL2A1 PTK7 0 0 0 153 1 1
COL2A1 CDH11 0 0 183 239 1 1
COL2A1 TGFBR2 0 0 302 329 1 1
COL2A1 RECQL4 0 0 55 215 1 1
COL2A1 ACTG1 0 0 295 326 1 1
COL2A1 ITGB5 0 600 98 639 1 1
COL2A1 MCAM 0 0 289 327 1 1
COL2A1 CTHRC1 0 0 163 195 1 1
COL2A1 TGFBR1 0 0 334 349 1 1
COL2A1 ZFPM1 0 0 0 154 1 1
COL2A1 PXDNL 0 0 0 249 1 1
COL2A1 CLSTN2 0 0 391 404 1 1
COL2A1 LAMC3 0 0 134 348 1 1
COL2A1 WISP3 0 0 282 282 1 1
COL2A1 MGLL 0 0 0 227 1 1
COL2A1 COL22A1 0 300 218 435 1 1
COL2A1 GLI1 0 0 325 391 1 2
COL2A1 RARA 0 0 49 159 1 2
COL2A1 VTN 0 0 167 187 1 1
COL2A1 C1QC 0 0 48 174 1 1
COL2A1 AKT3 0 0 67 163 1 2
COL2A1 NCAM1 0 0 206 241 1 1
COL2A1 LOXL3 0 0 204 338 1 1
COL2A1 T 0 0 46 174 1 1
COL2A1 ITGAM 0 0 146 154 1 1
COL2A1 RAC1 0 0 66 152 1 2
COL2A1 CTSK 0 0 324 367 1 2
COL2A1 COL6A6 0 300 164 363 1 1
COL2A1 CTSB 0 0 134 169 1 2
COL2A1 SIRT1 0 0 231 290 1 2
COL2A1 DLK1 0 0 124 224 1 1
COL2A1 SOX6 0 0 686 744 1 1
COL2A1 PCNA 0 0 0 158 1 2
COL2A1 WNT3A 0 0 370 420 1 2
COL2A1 ITGB3 0 900 81 924 1 1
COL2A1 TIA1 0 0 123 210 1 1
COL2A1 HRH3 0 0 74 174 1 1
COL2A1 FRMD6 0 0 134 227 1 1
COL2A1 BGN 213 0 510 629 1 1
COL2A1 FKBP9 145 0 0 189 1 1
COL2A1 PTGES 0 0 160 232 1 1
COL2A1 SDC1 0 900 52 901 1 1
COL2A1 C2orf82 0 0 241 302 1 1
COL2A1 SFRP2 0 0 226 272 1 1
COL2A1 EPYC 0 0 194 268 1 1
COL2A1 TOP2B 0 0 0 232 1 1
COL2A1 TLN2 0 0 0 173 1 1
COL2A1 FKBP10 0 0 112 253 1 1
COL2A1 EPAS1 0 0 217 288 1 2
COL2A1 GON4L 0 0 67 161 1 1
COL2A1 SOD2 0 0 167 197 1 2
COL2A1 GDF6 0 0 321 358 1 1
COL2A1 FOS 0 0 218 219 1 2
COL2A1 HEY2 0 0 134 175 1 1
COL2A1 TWIST1 0 0 263 284 1 1
COL2A1 PTPN11 0 0 162 176 1 1
COL2A1 CHD8 0 0 0 151 1 1
COL2A1 KRT36 0 0 67 320 1 1
COL2A1 COL9A2 213 300 707 702 1 1
COL2A1 EGFLAM 0 0 0 181 1 1
COL2A1 TBX10 0 0 0 154 1 1
COL2A1 CSF1 0 0 149 200 1 1
COL2A1 HDAC1 0 0 193 203 1 2
COL2A1 FABP4 0 0 306 316 1 1
COL2A1 BMPR1B 0 0 263 359 1 1
COL2A1 ALX3 0 0 181 253 1 1
COL2A1 MGP 0 0 323 337 1 1
COL2A1 MYH1 0 0 96 152 1 1
COL2A1 BARX2 0 0 234 246 1 1
COL2A1 WNT2 0 0 128 289 1 1
COL2A1 COL5A3 0 720 364 755 1 1
COL2A1 ADAMTSL1 0 0 134 255 1 1
COL2A1 CHUK 0 0 112 154 1 1
COL2A1 FGFRL1 0 0 103 160 1 1
COL2A1 ALOX5 0 0 54 194 1 1
COL2A1 NOTCH2 0 0 181 252 1 1
COL2A1 DLX3 0 0 124 205 1 1
COL2A1 TET1 0 0 71 232 1 1
COL2A1 GDF11 0 0 126 185 1 1
COL2A1 OSR2 0 0 203 218 1 1
COL2A1 TNN 0 0 181 198 1 1
COL2A1 MMP14 0 0 233 299 1 1
COL2A1 PPIC 0 0 0 157 1 1
COL2A1 IL1RL1 0 0 358 358 1 1
COL2A1 DCHS2 0 0 120 288 1 1
COL2A1 AFP 0 0 90 152 1 2
COL2A1 KRT35 0 0 0 215 1 1
COL2A1 CYP26A1 0 0 95 167 1 1
COL2A1 WNT7B 0 0 184 201 1 1
COL2A1 SMAD9 0 0 245 348 1 1
COL2A1 HIF1A 0 0 377 415 1 2
COL2A1 SP1 0 0 170 183 1 2
COL2A1 CAPN5 0 0 58 220 1 1
COL2A1 MATN4 0 0 392 473 1 1
COL2A1 IL1B 0 0 556 556 1 2
COL2A1 ID1 0 0 147 192 1 1
COL2A1 ADAMTS20 0 0 61 226 1 1
COL2A1 OPTC 0 0 265 291 1 1
COL2A1 CDH20 0 0 113 157 1 1
COL2A1 OAF 0 0 150 174 1 1
COL2A1 FAM20B 0 0 81 175 1 1
COL2A1 PRKAR2B 0 0 0 159 1 1
COL2A1 BAAT 0 0 306 306 1 1
COL2A1 DR1 0 0 123 165 1 1
COL2A1 TMEM229A 0 0 181 181 1 1
COL2A1 FGF13 0 0 392 401 1 1
COL2A1 PRICKLE1 0 0 108 157 1 1
COL2A1 SCO2 0 0 94 219 1 1
COL2A1 NOTCH1 0 0 339 396 1 2
COL2A1 TM2D3 0 0 388 388 1 1
COL2A1 GCFC2 0 0 160 231 1 1
COL2A1 RPL13A 0 0 290 290 1 1
COL2A1 SEC24D 0 0 173 244 1 1
COL2A1 MYO1H 0 0 150 175 1 1
COL2A1 POTEF 0 0 286 344 1 1
COL2A1 ACOT2 0 0 0 207 1 1
COL2A1 SMO 0 0 60 246 1 1
COL2A1 BMP3 0 0 391 416 1 1
COL2A1 CALM1 0 0 324 335 1 1
COL2A1 ADAMTS16 0 0 0 159 1 1
COL2A1 IL6 0 0 392 392 1 2
COL2A1 TNFRSF1A 0 0 66 249 1 1
COL2A1 MYOG 0 0 181 217 1 1
COL2A1 LEPRE1 0 600 218 688 1 1
COL2A1 TBX2 0 0 86 161 1 1
COL2A1 TECTA 0 0 136 240 1 1
COL2A1 IGFBP5 0 0 194 224 1 1
COL2A1 ACOT4 0 0 0 207 1 1
COL2A1 TGFB3 0 0 634 657 1 1
COL2A1 ELOVL2 0 0 0 292 1 1
COL2A1 MYH3 0 0 127 218 1 1
COL2A1 ANXA5 270 0 211 399 1 2
COL2A1 CCNB1 0 0 107 211 1 1
COL2A1 SPECC1L 0 0 90 203 1 1
COL2A1 TAGLN 0 0 218 224 1 1
COL2A1 PCSK6 0 0 112 182 1 1
COL2A1 PHEX 0 0 321 321 1 1
COL2A1 GPD1 0 0 155 173 1 1
COL2A1 COL11A2 0 900 764 921 1 1
COL2A1 GJB2 0 0 149 202 1 1
COL2A1 ALDH1A2 0 0 150 168 1 1
COL2A1 SOX3 0 0 136 243 1 1
COL2A1 CALCR 0 0 155 156 1 1
COL2A1 LECT1 0 0 395 517 1 1
COL2A1 P4HA2 0 900 181 921 1 1
COL2A1 TLL1 0 900 81 909 1 1
COL2A1 SOX12 0 0 134 217 1 1
COL2A1 GJB1 0 0 124 156 1 1
COL2A1 ANAPC5 0 0 410 422 1 1
COL2A1 EMCN 0 0 108 159 1 1
COL2A1 SMAD2 0 0 373 460 1 2
COL2A1 EMR1 0 0 0 173 1 1
COL2A1 TSPAN12 0 0 144 235 1 1
COL2A1 ZNF579 0 0 150 164 1 1
COL2A1 JAG2 0 0 70 150 1 1
COL2A1 PGAM4 0 0 0 256 1 1
COL2A1 NF1 0 0 108 151 1 1
COL2A1 HYAL2 0 0 45 253 1 1
COL2A1 MYC 0 0 234 234 1 2
COL2A1 PAX7 0 0 203 232 1 1
COL2A1 RXFP2 0 0 59 150 1 1
COL2A1 IGF1R 0 0 218 247 1 2
COL2A1 COL11A1 0 900 766 959 1 1
COL2A1 SDHC 0 0 209 209 1 1
COL2A1 FGF10 0 0 202 246 1 1
COL2A1 NOG 0 0 325 353 1 1
COL2A1 IRX5 0 0 124 196 1 1
COL2A1 SPTBN2 0 0 306 311 1 1
COL2A1 MYH10 0 0 0 163 1 1
COL2A1 HYAL4 0 0 0 250 1 1
COL2A1 RARG 0 0 49 159 1 1
COL2A1 DCHS1 0 0 0 172 1 1
COL2A1 MMP17 0 0 95 345 1 1
COL2A1 SMAD4 0 0 288 395 1 2
COL2A1 AKT2 0 0 67 163 1 2
COL2A1 C12orf4 0 0 103 202 1 1
COL2A1 FKBP7 0 0 0 243 1 1
COL2A1 OSM 0 0 171 171 1 1
COL2A1 MAP2K1 0 0 134 180 1 1
COL2A1 COL9A3 213 300 697 732 1 1
COL2A1 FBLN2 0 0 100 222 1 1
COL2A1 DHH 0 0 213 280 1 1
COL2A1 PCOLCE 213 900 95 936 1 1
COL2A1 S100A1 0 0 150 188 1 1
COL2A1 COL5A2 0 720 538 736 1 1
COL2A1 PITX2 0 0 122 179 1 1
COL2A1 LMNA 0 0 90 150 1 2
COL2A1 TCOF1 0 0 242 319 1 1
COL2A1 CRTAC1 0 0 203 218 1 1
COL2A1 FGF7 213 0 81 285 1 1
COL2A1 GNL3 0 0 150 191 1 1
COL2A1 PLOD1 130 600 174 741 1 1
COL2A1 NME3 0 0 0 211 1 1
COL2A1 C7orf49 0 0 489 489 1 1
COL2A1 LCP2 0 0 0 213 1 1
COL2A1 ADAMTS15 0 0 119 175 1 1
COL2A1 LAMB2 0 0 0 187 1 1
COL2A1 SETD8 0 0 0 162 1 1
COL2A1 WNT5B 0 0 242 300 1 1
COL2A1 MED23 0 0 66 160 1 1
COL2A1 CTBP2 0 0 76 158 1 1
COL2A1 RPGR 0 0 150 241 1 1
COL2A1 CACNA1F 0 0 142 251 1 1
COL2A1 C1QTNF7 0 0 0 188 1 1
COL2A1 MSRB3 0 0 77 175 1 1
COL2A1 EXT1 0 0 138 197 1 1
COL2A1 ANKH 0 0 112 151 1 1
COL2A1 HOXD13 0 0 242 293 1 1
COL2A1 CMSS1 0 0 134 238 1 1
COL2A1 STAT3 0 0 140 159 1 2
COL2A1 EZH2 0 0 150 174 1 2
COL2A1 HTRA1 213 0 86 273 1 1
COL2A1 DKK2 0 0 184 183 1 1
COL2A1 LEPR 0 0 66 160 1 1
COL2A1 CASP8 0 900 104 906 1 2
COL2A1 ITGB1 0 900 510 960 1 1
COL2A1 PGK1 0 0 141 174 1 2
COL2A1 NYX 0 0 124 287 1 1
COL2A1 HSPG2 0 0 391 601 1 1
COL2A1 DSPP 0 0 142 192 1 1
COL2A1 FAM161A 0 0 52 155 1 1
COL2A1 GPX5 0 0 49 237 1 1
COL2A1 NOTCH3 0 0 75 181 1 1
COL2A1 KCNJ13 0 0 398 398 1 1
COL2A1 FBLN1 0 0 204 332 1 1
COL2A1 TNXB 0 0 193 193 1 1
COL2A1 MYLK 0 0 91 197 1 1
COL2A1 TNFRSF10A 213 0 0 213 1 1
COL2A1 TUBB3 0 0 150 203 1 1
COL2A1 PLCL2 0 0 82 195 1 1
COL2A1 MATN1 213 0 631 719 1 1
COL2A1 GLI2 0 0 283 358 1 2
COL2A1 ADAMTSL4 0 0 108 234 1 1
COL2A1 PRPH2 0 0 94 190 1 1
COL2A1 ADAMTS10 0 0 182 214 1 1
COL2A1 BMP7 0 0 459 549 1 1
COL2A1 DLL3 0 0 120 175 1 1
COL2A1 LGALS4 0 0 127 188 1 1
COL2A1 RHOB 0 0 46 162 1 1
COL2A1 COL21A1 0 300 323 454 1 1
COL2A1 KIF20A 0 0 49 177 1 1
COL2A1 IL1A 0 0 253 252 1 1
COL2A1 SDCCAG8 0 0 0 173 1 1
COL2A1 HIST2H3PS2 0 0 180 195 1 1
COL2A1 PXN 0 0 67 151 1 1
COL2A1 CDH7 0 0 193 219 1 1
COL2A1 FLG 0 0 0 202 1 1
COL2A1 CTGF 0 0 418 443 1 1
COL2A1 COL13A1 0 300 246 421 1 1
COL2A1 NR3C1 0 0 113 221 1 1
COL2A1 PDGFA 270 0 122 331 1 1
COL2A1 ADIPOQ 0 0 207 252 1 2
COL2A1 LTBP1 0 0 134 186 1 1
COL2A1 VIM 0 0 171 219 1 2
COL2A1 MRPS25 0 0 73 242 1 1
COL2A1 ADAMTS2 0 900 391 945 1 1
COL2A1 TBX3 0 0 75 150 1 1
COL2A1 ITGA8 0 600 95 654 1 1
COL2A1 GDF2 0 0 205 238 1 1
COL2A1 NANOG 0 0 324 339 1 2
COL2A1 ZNF219 0 0 180 338 1 1
COL2A1 IMMT 0 0 109 190 1 1
COL2A1 SLIT1 0 0 74 183 1 1
COL2A1 CRABP1 0 0 107 160 1 1
COL2A1 IL17A 0 0 145 165 1 2
COL2A1 ETS1 0 0 181 225 1 1
COL2A1 CFD 0 0 172 171 1 1
COL2A1 STK16 0 0 54 241 1 1
COL2A1 COL5A1 0 720 561 831 1 1
COL2A1 ACVR1 0 0 265 282 1 1
COL2A1 SEC23A 0 0 150 219 1 2
COL2A1 CDKN1C 0 0 200 217 1 1
COL2A1 PPIB 0 600 117 631 1 1
COL2A1 NES 0 0 398 434 1 2
COL2A1 ITGA1 0 900 181 914 1 1
COL2A1 KIF11 0 0 81 173 1 1
COL2A1 HNRNPA1 0 0 54 170 1 1
COL2A1 NR2F2 0 0 248 261 1 1
COL2A1 CALB1 0 0 306 316 1 1
COL2A1 ARID5A 0 0 167 167 1 1
COL2A1 ITPR3 0 0 0 163 1 1
COL2A1 DVL3 0 0 0 229 1 1
COL2A1 CXCL6 0 0 181 181 1 1
COL2A1 DTX1 0 0 170 169 1 1
COL2A1 COLQ 0 0 0 160 1 1
COL2A1 ARID1B 0 0 293 293 1 1
COL2A1 DLL1 0 0 162 193 1 1
COL2A1 IGFBP3 0 0 181 181 1 2
COL2A1 XYLT2 0 0 108 165 1 1
COL2A1 ADAMTS19 0 0 81 159 1 1
COL2A1 AGRN 0 0 181 295 1 1
COL2A1 MMP2 130 0 341 518 1 2
COL2A1 SOX13 0 0 91 201 1 1
COL2A1 MIA 0 0 402 460 1 2
COL2A1 LAMB1 0 0 235 352 1 1
COL2A1 MED12 0 0 162 161 1 1
COL2A1 DLEC1 0 0 0 162 1 1
COL2A1 ALX1 0 0 181 285 1 1
COL2A1 SHH 0 0 359 413 1 2
COL2A1 LTBP2 0 0 167 197 1 1
COL2A1 FOXD3 0 0 170 274 1 1
COL2A1 LOXL4 213 0 150 422 1 1
COL2A1 ETV4 0 0 155 210 1 1
COL2A1 CRTC2 0 0 309 309 1 1
COL2A1 GDF10 0 0 254 285 1 1
COL2A1 RHOA 0 0 181 293 1 2
COL2A1 ITGA11 0 600 170 669 1 1
COL2A1 FGF4 0 0 157 249 1 1
COL2A1 CXCL12 0 0 253 252 1 2
COL2A1 TPM1 0 0 134 210 1 1
COL2A1 CARTPT 0 0 54 155 1 1
COL2A1 PGAM2 0 0 54 440 1 1
COL2A1 RBM14 0 0 262 262 1 1
COL2A1 ITGB7 0 600 0 669 1 1
COL2A1 WNT6 0 0 150 151 1 1
COL2A1 DNMT1 0 0 124 163 1 2
COL2A1 INS 0 0 390 428 1 2
COL2A1 ACTB 0 0 502 542 1 2
COL2A1 ADAMTS5 0 0 738 759 1 1
COL2A1 C3orf49 0 0 244 243 1 1
COL2A1 FAT3 0 0 75 157 1 1
COL2A1 GLI3 0 0 234 318 1 1
COL2A1 B2M 0 0 233 232 1 1
COL2A1 KEAP1 232 0 0 249 1 2
COL2A1 PROM1 0 0 134 177 1 2
COL2A1 SP7 0 0 604 701 1 1
COL2A1 FOSL1 0 0 96 259 1 1
COL2A1 PDIA2 270 0 75 382 1 1
COL2A1 PTCH2 0 0 54 150 1 1
COL2A1 HAPLN3 0 0 170 170 1 1
COL2A1 ALX4 0 0 116 255 1 1
COL2A1 CEBPA 0 0 208 216 1 1
COL2A1 MMP12 0 0 210 226 1 1
COL2A1 ANPEP 0 0 143 181 1 1
COL2A1 NTN1 0 0 59 171 1 1
COL2A1 MITF 0 0 112 173 1 2
COL2A1 HAS2 0 0 325 339 1 1
COL2A1 NFATC2 0 0 203 212 1 1
COL2A1 TBX4 0 0 145 210 1 1
COL2A1 SEC13 0 0 60 158 1 1
COL2A1 APLP2 0 0 52 177 1 1
COL2A1 DUSP13 0 0 71 331 1 1
COL2A1 LAMA3 0 0 144 387 1 1
COL2A1 GPC3 0 0 156 281 1 1
COL2A1 TRIP11 0 0 510 510 1 1
COL2A1 MYBPC1 0 0 54 210 1 1
COL2A1 GRM6 0 0 66 167 1 1
COL2A1 MSX2 0 0 349 375 1 1
COL2A1 C1QB 0 0 0 183 1 1
COL2A1 SMURF2 0 0 206 217 1 1
COL2A1 ADAM12 0 0 150 169 1 1
COL2A1 SRC 0 0 143 209 1 2
COL2A1 MEOX1 0 0 183 195 1 1
COL2A1 WWP2 0 0 324 338 1 1
COL2A1 A2M 0 0 113 157 1 1
COL2A1 PKD1 270 0 52 300 1 1
COL2A1 RPP40 0 0 61 154 1 1
COL2A1 RHOC 0 0 0 172 1 1
COL2A1 SPON1 0 0 0 165 1 1
COL2A1 MMP23B 0 0 107 275 1 1
COL2A1 P4HA3 0 900 125 911 1 1
COL2A1 USH2A 0 0 0 215 1 1
COL2A1 FGF3 0 0 171 198 1 1
COL2A1 P4HA1 0 900 195 919 1 1
COL2A1 CHRD 0 0 266 490 1 1
COL2A1 ITGB6 0 600 96 688 1 1
COL2A1 NID1 0 0 141 372 1 1
COL2A1 FOXF2 0 0 242 241 1 1
COL2A1 HMGA2 0 0 136 190 1 1
COL2A1 ERBB2 0 0 81 162 1 2
COL2A1 DSTN 0 0 0 155 1 1
COL2A1 SLIT3 0 0 66 176 1 1
COL2A1 ATF4 0 0 210 214 1 2
COL2A1 COL19A1 0 300 142 395 1 1
COL2A1 PRDM16 0 0 91 158 1 1
COL2A1 LAMB3 0 0 184 216 1 1
COL2A1 PTHLH 0 0 563 630 1 1
COL2A1 MKI67 0 0 75 197 1 2
COL2A1 AKT1 0 0 292 365 1 2
COL2A1 TGFB2 0 0 368 408 1 1
COL2A1 CAPN1 0 0 45 176 1 2
COL2A1 PPARG 0 0 419 441 1 2
COL2A1 SLIT2 0 0 0 175 1 1
COL2A1 KIF26A 0 0 0 182 1 1
COL2A1 RUNX2 0 0 747 822 1 2
COL2A1 FMOD 0 0 587 611 1 1
COL2A1 AVL9 0 0 0 159 1 1
COL2A1 ACE2 0 0 0 179 1 2
COL2A1 LRCH1 0 0 390 412 1 1
COL2A1 COL1A2 0 720 686 799 1 1
COL2A1 IKBKB 0 0 108 150 1 2
COL2A1 SLC10A1 0 0 0 229 1 1
COL2A1 COL6A1 213 300 503 572 1 1
COL2A1 KLF4 0 0 193 206 1 2
COL2A1 FGFR1 0 0 257 341 1 1
COL2A1 COLGALT2 408 600 0 753 1 1
COL2A1 WISP1 0 0 157 206 1 1
COL2A1 VDR 0 0 297 338 1 2
COL2A1 IL1RN 0 0 160 159 1 1
COL2A1 PTGFR 0 0 137 162 1 1
COL2A1 TDG 0 0 398 398 1 1
COL2A1 MMP3 0 0 635 657 1 1
COL2A1 DCT 0 0 107 227 1 1
COL2A1 NT5E 0 0 394 431 1 1
COL2A1 ITGA9 0 600 95 654 1 1
COL2A1 MEF2C 0 0 296 319 1 1
COL2A1 MMP25 0 0 107 355 1 1
COL2A1 CHRNA1 0 0 95 159 1 1
COL2A1 PIH1D1 0 0 0 167 1 1
COL2A1 TNF 0 0 391 419 1 2
COL2A1 MSX1 0 0 358 385 1 1
COL2A1 PAX3 0 0 210 256 1 1
COL2A1 MYO18B 0 0 108 169 1 1
COL2A1 ENAM 0 0 134 476 1 1
COL2A1 NFAT5 0 0 123 177 1 1
COL2A1 MMP8 0 0 248 375 1 1
COL2A1 SLC35D1 0 0 187 217 1 1
COL2A1 CD9 0 0 134 167 1 1
COL2A1 C1QTNF9 665 0 0 706 1 1
COL2A1 AGT 0 0 0 224 1 1
COL2A1 LAMC1 0 0 123 340 1 1
COL2A1 TFAP2A 0 0 171 218 1 1
COL2A1 PLOD2 0 600 147 706 1 1
COL2A1 ARNTL 0 0 144 162 1 1
COL2A1 THBS2 0 0 258 286 1 1
COL2A1 MMP27 0 0 0 305 1 1
COL2A1 PGAM1 0 0 49 263 1 1
COL2A1 CDH5 0 0 143 226 1 1
COL2A1 ATF3 0 0 142 215 1 2
COL2A1 PARD6A 0 0 146 161 1 1
COL2A1 KIF26B 0 0 61 195 1 1
COL2A1 LOX 0 0 269 303 1 2
COL2A1 MMP19 0 0 96 174 1 1
COL2A1 SERPINE1 0 0 166 181 1 1
COL2A1 LEPREL2 0 600 0 623 1 1
COL2A1 ADAMTS12 0 0 193 292 1 1
COL2A1 HDAC7 0 0 150 169 1 1
COL2A1 SREBF2 0 0 64 175 1 1
COL2A1 DLX6 0 0 123 188 1 1
COL2A1 POU1F1 0 0 48 161 1 1
COL2A1 QSOX1 0 0 45 332 1 1
COL2A1 FOXA2 0 0 181 198 1 1
COL2A1 SMAD6 0 0 249 300 1 1
COL2A1 HPRT1 0 0 204 209 1 1
COL2A1 CD97 0 0 0 173 1 1
COL2A1 LIN28A 0 0 164 195 1 1
COL2A1 COL6A5 0 300 74 314 1 1
COL2A1 TBX1 0 0 95 202 1 1
COL2A1 DUSP6 0 0 125 151 1 1
COL2A1 WNT10B 0 0 181 215 1 1
COL2A1 SFTPD 0 0 0 173 1 1
COL2A1 HGF 0 0 143 201 1 2
COL2A1 POU5F1 0 0 322 334 1 2
COL2A1 SLC39A8 0 0 171 171 1 1
COL2A1 ADAMTS3 0 900 681 971 1 1
COL2A1 BMPR2 0 0 281 307 1 1
COL2A1 MECOM 0 0 49 163 1 1
COL2A1 GAPDHS 0 0 0 229 1 1
COL2A1 MMP11 0 0 90 341 1 1
COL2A1 NME8 0 0 330 356 1 1
COL2A1 NFATC1 0 0 217 217 1 2
COL2A1 HOXD12 0 0 150 254 1 1
COL2A1 FZD9 0 0 143 228 1 1
COL2A1 BMPR1A 0 0 284 382 1 1
COL2A1 PTH2R 0 0 141 213 1 1
COL2A1 ARTN 0 0 48 463 1 1
COL2A1 KAT5 0 0 150 180 1 1
COL2A1 PAX1 0 0 420 446 1 1
COL2A1 HOXD11 0 0 150 196 1 1
COL2A1 NPPC 0 0 486 485 1 1
COL2A1 NGFR 0 0 181 205 1 1
COL2A1 CDX2 0 0 329 340 1 1
COL2A1 ADAMTS7 0 0 264 378 1 1
COL2A1 RARB 0 0 114 323 1 1
COL2A1 KIT 0 0 134 208 1 2
COL2A1 SOX10 0 0 397 778 1 1
COL2A1 ENG 0 0 465 472 1 2
COL2A1 GUCY2D 0 0 95 193 1 1
COL2A1 MARCO 0 540 0 599 1 1
COL2A1 IGF2 0 0 234 270 1 1
COL2A1 CRB2 0 0 0 150 1 1
COL2A1 IL10 0 0 146 167 1 2
COL2A1 SNAI1 0 0 181 187 1 1
COL2A1 FGFR4 0 0 124 208 1 1
COL2A1 ARVCF 0 0 0 158 1 1
COL2A1 GFRA1 0 0 47 216 1 1
COL2A1 TNPO1 0 0 0 213 1 1
COL2A1 GDF5 0 0 615 668 1 1
COL2A1 PAPLN 0 0 0 322 1 1
COL2A1 WNT10A 0 0 134 170 1 1
COL2A1 NR1H4 0 0 0 157 1 1
COL2A1 TIMP2 0 0 270 279 1 1
COL2A1 SDC2 0 0 181 218 1 1
COL2A1 ITM2A 0 0 124 209 1 1
COL2A1 MATN3 0 0 556 600 1 1
COL2A1 LAMA1 0 0 181 313 1 1
COL2A1 HAND2 0 0 230 254 1 1
COL2A1 TTK 0 0 0 168 1 1
COL2A1 COL4A6 0 300 265 557 1 1
COL2A1 BARX1 0 0 232 396 1 1
COL2A1 TERT 0 0 181 201 1 2
COL2A1 SURF4 0 0 48 360 1 1
COL2A1 FN1 213 0 465 585 1 2
COL2A1 TBP 0 0 186 192 1 1
COL2A1 MMP13 213 0 803 865 1 2
COL2A1 NONO 0 0 171 259 1 1
COL2A1 CA12 0 0 261 281 1 1
COL2A1 ACVRL1 0 0 183 201 1 1
COL2A1 COCH 417 0 438 667 1 1
COL2A1 PLK3 0 0 0 165 1 1
COL2A1 SMAD7 0 0 218 268 1 1
COL2A1 ESR1 0 0 208 220 1 2
COL2A1 WLS 0 0 193 207 1 1
COL2A1 DFNA5 0 0 63 163 1 1
COL2A1 ADAMTS14 0 900 215 929 1 1
COL2A1 CPNE8 0 0 66 169 1 1
COL2A1 KIF3A 0 0 108 173 1 1
COL2A1 ELN 0 0 408 421 1 1
COL2A1 C1QA 213 0 0 299 1 1
COL2A1 BMP8A 0 0 81 173 1 1
COL2A1 PAPSS2 0 0 228 276 1 1
COL2A1 CILP2 0 0 218 246 1 1
COL2A1 HES3 0 0 71 258 1 1
COL2A1 DLX5 0 0 322 332 1 1
COL2A1 MYH11 0 0 170 221 1 1
COL2A1 COL9A1 656 300 763 857 1 1
COL2A1 THBS3 0 0 183 237 1 1
COL2A1 CSPG4 0 0 166 201 1 1
COL2A1 FOXC1 0 0 156 155 1 1
COL2A1 WBP2 0 0 47 165 1 1
COL2A1 HLA-DRA 800 0 0 800 1 1
COL2A1 ZNF644 0 0 113 217 1 1
COL2A1 BECN1 0 0 119 152 1 2
COL2A1 HLA-DPA1 0 0 297 297 1 1
COL2A1 THBS1 270 0 218 427 1 1
COL2A1 ITGA2 0 900 182 914 1 1
COL2A1 TECTB 0 0 434 434 1 1
COL2A1 EVC2 0 0 168 193 1 1
COL2A1 FGF23 0 0 108 194 1 1
COL2A1 PIAS1 0 0 70 276 1 1
COL2A1 BCAN 0 0 150 182 1 1
COL2A1 TRIP10 0 0 62 207 1 1
COL2A1 AMH 0 0 143 200 1 1
COL2A1 EMR3 0 0 0 173 1 1
COL2A1 EMID1 0 0 0 204 1 1
COL2A1 ITGB2 0 0 95 291 1 1
COL2A1 HOXC8 0 0 134 233 1 1
COL2A1 DTX2 0 0 138 180 1 1
COL2A1 NKX3-2 0 0 504 544 1 1
COL2A1 PTH 0 0 374 436 1 1
COL2A1 COL12A1 0 300 421 515 1 1
COL2A1 KDM6B 0 0 135 160 1 1
COL2A1 MMP24 0 0 120 326 1 1
COL2A1 GUCA2A 0 0 390 390 1 1
COL2A1 COL15A1 0 300 230 403 1 1
COL2A1 LAMA2 0 0 211 297 1 1
COL2A1 PDIA4 0 0 108 275 1 1
COL2A1 TWIST2 0 0 284 317 1 1
COL2A1 ACOT1 0 0 0 207 1 1
COL2A1 GPR126 0 0 108 161 1 1
COL2A1 SOX1 0 0 206 235 1 1
COL2A1 FGF9 0 0 165 210 1 1
COL2A1 LAMB4 0 0 139 185 1 1
COL2A1 CEBPB 0 0 203 207 1 2
COL2A1 WNT3 0 0 166 212 1 1
COL2A1 GUSB 0 0 117 177 1 1
COL2A1 ARRB2 0 0 0 215 1 1
COL2A1 CDKN2A 0 0 217 230 1 2
COL2A1 GSK3B 0 0 125 208 1 2
COL2A1 S100B 0 0 132 159 1 1
COL2A1 FGF8 0 0 211 241 1 1
COL2A1 QSOX2 0 0 0 189 1 1
COL2A1 COL4A5 0 300 243 493 1 1
COL2A1 ACOT6 0 0 91 231 1 1
COL2A1 LTBP3 0 0 154 202 1 1
COL2A1 IHH 0 0 683 710 1 1
COL2A1 COL6A2 0 300 391 516 1 1
COL2A1 HARS 0 0 57 166 1 1
COL2A1 CYP26B1 0 0 100 206 1 1
COL2A1 EGLN1 0 0 94 150 1 1
COL2A1 ENPP1 0 0 242 241 1 1
COL2A1 ERBB3 0 0 57 177 1 1
COL2A1 CASP3 0 0 296 296 1 2
COL2A1 PTGS2 0 0 335 369 1 2
COL2A1 TGFBR3 0 0 190 195 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0042289 Molecular Function MHC class II protein binding enables IPI
GO:0030020 Molecular Function extracellular matrix structural constituent conferring tensile strength enables HDA
GO:0030020 Molecular Function extracellular matrix structural constituent conferring tensile strength enables IBA
GO:0030020 Molecular Function extracellular matrix structural constituent conferring tensile strength enables IC
GO:0030020 Molecular Function extracellular matrix structural constituent conferring tensile strength enables RCA
GO:0046872 Molecular Function metal ion binding enables IEA
GO:0048407 Molecular Function platelet-derived growth factor binding enables IDA
GO:0042803 Molecular Function protein homodimerization activity enables IPI
GO:0043394 Molecular Function proteoglycan binding enables IDA
GO:0097065 Biological Process anterior head development involved_in IEA
GO:0001502 Biological Process cartilage condensation involved_in IEA
GO:0051216 Biological Process cartilage development involved_in TAS
GO:0060351 Biological Process cartilage development involved in endochondral bone morphogenesis involved_in IEA
GO:0071773 Biological Process cellular response to BMP stimulus involved_in IEA
GO:0007417 Biological Process central nervous system development involved_in IEA
GO:0002062 Biological Process chondrocyte differentiation involved_in IEA
GO:0030199 Biological Process collagen fibril organization involved_in IBA
GO:0030199 Biological Process collagen fibril organization involved_in IMP
GO:0060272 Biological Process embryonic skeletal joint morphogenesis involved_in IMP
GO:0001958 Biological Process endochondral ossification involved_in IEA
GO:0097192 Biological Process extrinsic apoptotic signaling pathway in absence of ligand involved_in IEA
GO:0003007 Biological Process heart morphogenesis involved_in IEA
GO:0042472 Biological Process inner ear morphogenesis involved_in IEA
GO:0060174 Biological Process limb bud formation involved_in IEA
GO:2001240 Biological Process negative regulation of extrinsic apoptotic signaling pathway in absence of ligand involved_in IEA
GO:0030903 Biological Process notochord development involved_in IBA
GO:0071599 Biological Process otic vesicle development involved_in IEA
GO:0006029 Biological Process proteoglycan metabolic process involved_in IEA
GO:0010468 Biological Process regulation of gene expression involved_in IEA
GO:0060021 Biological Process roof of mouth development involved_in IEA
GO:0007605 Biological Process sensory perception of sound involved_in IMP
GO:0001501 Biological Process skeletal system development involved_in IBA
GO:0001501 Biological Process skeletal system development involved_in IMP
GO:0001894 Biological Process tissue homeostasis involved_in IEA
GO:0007601 Biological Process visual perception involved_in IMP
GO:0005604 Cellular Component basement membrane located_in IEA
GO:0005585 Cellular Component collagen type II trimer part_of IBA
GO:0005585 Cellular Component collagen type II trimer part_of IDA
GO:0005592 Cellular Component collagen type XI trimer part_of NAS
GO:0062023 Cellular Component collagen-containing extracellular matrix located_in HDA
GO:0062023 Cellular Component collagen-containing extracellular matrix is_active_in IBA
GO:0062023 Cellular Component collagen-containing extracellular matrix located_in NAS
GO:0005788 Cellular Component endoplasmic reticulum lumen located_in TAS
GO:0005576 Cellular Component extracellular region located_in HDA
GO:0005576 Cellular Component extracellular region located_in TAS
GO:0005615 Cellular Component extracellular space is_active_in IBA
GO:0005615 Cellular Component extracellular space located_in IMP
Pathways
Name DB ID
Developmental Biology Reactome R-HSA-1266738
Adaptive Immune System Reactome R-HSA-1280218
Collagen degradation Reactome R-HSA-1442490
Degradation of the extracellular matrix Reactome R-HSA-1474228
Extracellular matrix organization Reactome R-HSA-1474244
Collagen formation Reactome R-HSA-1474290
Signal Transduction Reactome R-HSA-162582
Collagen biosynthesis and modifying enzymes Reactome R-HSA-1650814
Immune System Reactome R-HSA-168256
Signaling by PDGF Reactome R-HSA-186797
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Reactome R-HSA-198933
Assembly of collagen fibrils and other multimeric structures Reactome R-HSA-2022090
Integrin cell surface interactions Reactome R-HSA-216083
Non-integrin membrane-ECM interactions Reactome R-HSA-3000171
ECM proteoglycans Reactome R-HSA-3000178
NCAM signaling for neurite out-growth Reactome R-HSA-375165
NCAM1 interactions Reactome R-HSA-419037
Axon guidance Reactome R-HSA-422475
Signaling by MET Reactome R-HSA-6806834
MET activates PTK2 signaling Reactome R-HSA-8874081
MET promotes cell motility Reactome R-HSA-8875878
Collagen chain trimerization Reactome R-HSA-8948216
Signaling by Receptor Tyrosine Kinases Reactome R-HSA-9006934
Nervous system development Reactome R-HSA-9675108
Neural crest differentiation (WP2064) WikiPathways WP2064_r117162
Focal adhesion (WP306) WikiPathways WP306_r116784
2q11.2 copy number variation syndrome (WP5221) WikiPathways WP5221_r122738
Interactions between LOXL4 and oxidative stress pathway (WP3670) WikiPathways WP3670_r117829
Endochondral ossification with skeletal dysplasias (WP4808) WikiPathways WP4808_r117708
Focal adhesion: PI3K-Akt-mTOR-signaling pathway (WP3932) WikiPathways WP3932_r124527
Spinal cord injury (WP2431) WikiPathways WP2431_r120812
Endochondral ossification (WP474) WikiPathways WP474_r117098
PI3K-Akt signaling pathway (WP4172) WikiPathways WP4172_r122580
Transcripts
Accession Version MolecularType Name NCBI Comments
XM_017018830 1 mRNA transcript variant X3 NC_000012 Reference
XM_017018829 1 mRNA transcript variant X2 NC_000012 Reference
XM_017018828 1 mRNA transcript variant X1 NC_000012 Reference
XM_047428315 1 mRNA transcript variant X5 NC_000012 Reference
NM_033150 3 mRNA transcript variant 2 NC_000012 Reference
NM_001844 5 mRNA transcript variant 1 NC_000012 Reference
XM_017018831 3 mRNA transcript variant X4 NC_000012 Reference