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CMBL

carboxymethylenebutenolidase homolog
General Information
Name carboxymethylenebutenolidase homolog
Alias
  • carboxymethylenebutenolidase homolog
  • carboxymethylenebutenolidase homolog (Pseudomonas)
  • carboxymethylenebutenolidase-like (Pseudomonas)
Gene_family
organism Homo sapiens
entrez_id 134147
location 5p15.2
transcript_count 6
exon_count 8
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez CMBL (EC 3.1.1.45) is a cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL preferentially cleaves cyclic esters, and it activates medoxomil-ester prodrugs in which the medoxomil moiety is linked to an oxygen atom (Ishizuka et al., 2010 [PubMed 20177059]).[supplied by OMIM, Apr 2010]
    Stringdb Carboxymethylenebutenolidase homolog; Cysteine hydrolase. Can convert the prodrug olmesartan medoxomil into its pharmacologically active metabolite olmerstatan, an angiotensin receptor blocker, in liver and intestine. May also activate beta-lactam antibiotics faropenem medoxomil and lenampicillin
    nextProt Cysteine hydrolase. Can convert the prodrug olmesartan medoxomil into its pharmacologically active metabolite olmerstatan, an angiotensin receptor blocker, in liver and intestine. May also activate beta-lactam antibiotics faropenem medoxomil and lenampicillin.
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
CMBL BioGRID SNCA GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
CMBL BioGRID TRIM67 GeneID BioGRID Affinity Capture-MS
CMBL BioGRID CCNF GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
CMBL BioGRID ZRANB1 GeneID BioGRID Affinity Capture-MS
CMBL BioGRID AR GeneID BioGRID Affinity Capture-MS
CMBL BioGRID PRKN GeneID BioGRID Affinity Capture-MS
CMBL BioGRID BROX GeneID BioGRID Co-fractionation
CMBL BioGRID MYDGF GeneID BioGRID Co-fractionation
CMBL BioGRID RFK GeneID BioGRID Co-fractionation
CMBL BioGRID PPIL1 GeneID BioGRID Co-fractionation
CMBL BioGRID LACTB2 GeneID BioGRID Co-fractionation
CMBL BioGRID PTGR1 GeneID BioGRID Co-fractionation
CMBL BioGRID SELENBP1 GeneID BioGRID Co-fractionation
CMBL BioGRID AKR1C3 GeneID BioGRID Co-fractionation
CMBL BioGRID TST GeneID BioGRID Co-fractionation
CMBL BioGRID SOD2 GeneID BioGRID Co-fractionation
CMBL BioGRID PGM1 GeneID BioGRID Co-fractionation
CMBL BioGRID MDH1 GeneID BioGRID Co-fractionation
CMBL BioGRID FKBP1A GeneID BioGRID Co-fractionation
CMBL BioGRID FHL1 GeneID BioGRID Co-fractionation
CMBL BioGRID FABP5 GeneID BioGRID Co-fractionation
CMBL BioGRID NQO1 GeneID BioGRID Co-fractionation
CMBL BioGRID CAPG GeneID BioGRID Co-fractionation
CMBL BioGRID ANXA11 GeneID BioGRID Co-fractionation
CMBL BioGRID ADH5 GeneID BioGRID Co-fractionation
CMBL BioGRID ACP2 GeneID BioGRID Co-fractionation
CMBL BioGRID ABAT GeneID BioGRID Co-fractionation
CMBL BioGRID TRAPPC13 GeneID BioGRID Affinity Capture-MS
CMBL BioGRID TRAPPC11 GeneID BioGRID Affinity Capture-MS
CMBL BioGRID TRAPPC1 GeneID BioGRID Affinity Capture-MS
CMBL BioGRID TRAPPC2L GeneID BioGRID Affinity Capture-MS
CMBL BioGRID PPME1 GeneID BioGRID Affinity Capture-MS
CMBL BioGRID TRAPPC4 GeneID BioGRID Affinity Capture-MS
CMBL BioGRID TRAPPC12 GeneID BioGRID Affinity Capture-MS
CMBL BioGRID TRAPPC8 GeneID BioGRID Affinity Capture-MS
CMBL BioGRID PAGE4 GeneID BioGRID Affinity Capture-MS
CMBL BioGRID SMARCA2 GeneID BioGRID Affinity Capture-MS
CMBL BioGRID DDRGK1 GeneID BioGRID Affinity Capture-MS
CMBL BioGRID NAP1L5 GeneID BioGRID Affinity Capture-MS
CMBL BioGRID ZNF514 GeneID BioGRID Affinity Capture-MS
CMBL BioGRID QPCT GeneID BioGRID Affinity Capture-MS
CMBL BioGRID TSPYL4 GeneID BioGRID Affinity Capture-MS
CMBL BioGRID STK38L GeneID BioGRID Affinity Capture-MS
CMBL BioGRID PLPBP GeneID BioGRID Affinity Capture-MS
CMBL BioGRID CTCF GeneID BioGRID Affinity Capture-MS
CMBL BioGRID TRIM24 GeneID BioGRID Affinity Capture-MS
CMBL BioGRID TRA2B GeneID BioGRID Affinity Capture-MS
CMBL BioGRID SRSF1 GeneID BioGRID Affinity Capture-MS
CMBL BioGRID EMC4 GeneID BioGRID Affinity Capture-MS
CMBL BioGRID PLEKHA4 GeneID BioGRID Affinity Capture-MS
CMBL BioGRID USP14 GeneID BioGRID Affinity Capture-MS
CMBL BioGRID VIRMA GeneID BioGRID Affinity Capture-MS
CMBL BioGRID AGR2 GeneID BioGRID Proximity Label-MS
CMBL BioGRID MEPCE GeneID BioGRID Affinity Capture-MS
CMBL BioGRID LARP7 GeneID BioGRID Affinity Capture-MS
CMBL BioGRID HEXIM1 GeneID BioGRID Affinity Capture-MS
CMBL BioGRID EFTUD2 GeneID BioGRID Affinity Capture-MS
CMBL BioGRID PIH1D1 GeneID BioGRID Affinity Capture-MS
CMBL BioGRID AAR2 GeneID BioGRID Affinity Capture-MS
CMBL BioGRID UBE2M GeneID BioGRID Affinity Capture-MS
CMBL BioGRID ZNF598 GeneID BioGRID Affinity Capture-MS
CMBL BioGRID CRBN GeneID BioGRID Affinity Capture-MS
CMBL BioGRID Crocc GeneID BioGRID Affinity Capture-MS
CMBL BioGRID Chmp6 GeneID BioGRID Affinity Capture-MS
CMBL BioGRID KIF20B GeneID BioGRID Affinity Capture-MS
CMBL BioGRID SAP30 GeneID BioGRID Affinity Capture-MS
CMBL BioGRID SMS GeneID BioGRID Affinity Capture-MS
CMBL BioGRID BAG3 GeneID BioGRID Affinity Capture-Luminescence
CMBL BioGRID PAN2 GeneID BioGRID Affinity Capture-MS
CMBL BioGRID SMURF1 GeneID BioGRID Affinity Capture-MS
CMBL BioGRID H2AX GeneID BioGRID Affinity Capture-MS
CMBL BioGRID CD2BP2 GeneID BioGRID Affinity Capture-MS
CMBL BioGRID CUL2 GeneID BioGRID Affinity Capture-MS
CMBL BioGRID EIF4A2 GeneID BioGRID Affinity Capture-MS
CMBL BioGRID ATIC GeneID BioGRID Affinity Capture-MS
CMBL BioGRID ARRB1 GeneID BioGRID Affinity Capture-MS
StringDB
A B experiments database textmining combined score hadb nhadb
CMBL RRP7A 0 0 211 386 1 1
CMBL IL13 0 0 329 329 1 2
CMBL COMTD1 0 0 0 152 1 1
CMBL REN 0 0 67 259 1 1
CMBL SULT1C2 0 0 0 154 1 1
CMBL PPM1B 0 0 0 156 1 1
CMBL ANG 0 0 0 221 1 2
CMBL DPEP1 0 0 0 301 1 1
CMBL NME2 0 0 82 172 1 1
CMBL COX6A1 0 0 0 204 1 1
CMBL PPME1 0 0 0 172 1 1
CMBL ACSM3 0 0 0 203 1 1
CMBL A1CF 0 0 0 238 1 1
CMBL GFPT1 0 0 0 236 1 1
CMBL LIX1 0 0 167 320 1 1
CMBL NLN 0 0 57 481 1 1
CMBL HAAO 0 0 0 323 1 1
CMBL RPE 0 0 0 218 1 1
CMBL SLC16A9 0 0 0 318 1 1
CMBL KAT8 0 0 81 176 1 1
CMBL MASP2 0 0 88 249 1 1
CMBL HADH 0 0 0 489 1 1
CMBL HIST3H3 0 0 154 153 1 1
CMBL TXNRD1 0 0 57 310 1 1
CMBL PGM3 0 0 0 187 1 1
CMBL SMPD1 0 0 0 201 1 1
CMBL ZADH2 0 0 0 188 1 1
CMBL TSPO 0 0 0 183 1 1
CMBL AK1 0 0 96 197 1 1
CMBL PDCD11 0 0 0 215 1 1
CMBL ETFB 0 0 0 194 1 1
CMBL GPI 0 0 67 193 1 2
CMBL TARBP1 0 0 189 291 1 1
CMBL CSTF2 0 0 0 185 1 1
CMBL UNC13B 0 0 75 235 1 1
CMBL PTGR2 0 0 0 188 1 1
CMBL STAMBPL1 0 0 0 189 1 1
CMBL SNRNP35 0 0 0 185 1 1
CMBL S100A12 0 0 44 155 1 1
CMBL HN1L 0 0 155 301 1 1
CMBL ENSG00000250644 0 0 0 239 1 1
CMBL STARD10 0 0 0 163 1 1
CMBL FTH1 0 0 0 288 1 1
CMBL PGA4 0 0 0 239 1 1
CMBL FKBP10 0 0 0 240 1 1
CMBL SNRPB 0 0 113 165 1 1
CMBL AKR1A1 0 0 112 293 1 1
CMBL PGM2 0 0 0 187 1 1
CMBL SMS 226 0 0 277 1 1
CMBL MECR 0 0 0 257 1 1
CMBL C14orf1 0 0 209 246 1 1
CMBL ASAH2 0 0 45 408 1 1
CMBL ACADSB 0 0 75 342 1 1
CMBL GAS7 0 0 103 254 1 1
CMBL AIFM3 0 0 0 265 1 1
CMBL ZNF598 270 0 0 270 1 1
CMBL CYP3A43 0 0 137 248 1 1
CMBL TRDMT1 0 0 90 230 1 1
CMBL PPM1N 0 0 0 156 1 1
CMBL CBX7 0 0 75 172 1 1
CMBL MAT1A 0 0 0 215 1 1
CMBL EDC3 0 0 0 198 1 1
CMBL SUCLG2 0 0 0 208 1 1
CMBL RPS11 0 0 0 242 1 1
CMBL DDAH1 0 0 0 352 1 1
CMBL PON1 0 0 155 181 1 1
CMBL OSBPL11 0 0 0 151 1 1
CMBL PKP4 0 0 0 150 1 1
CMBL SLC40A1 0 0 72 290 1 1
CMBL MASP1 0 0 75 333 1 1
CMBL CPOX 0 0 0 155 1 1
CMBL GSTM2 0 0 103 284 1 1
CMBL ACADVL 0 0 0 320 1 1
CMBL FKBP9 0 0 0 240 1 1
CMBL GRPEL2 0 0 0 163 1 1
CMBL SRSF5 0 0 0 185 1 1
CMBL EEF1G 0 0 0 194 1 1
CMBL STK38L 274 0 0 274 1 1
CMBL NAP1L4 274 0 0 274 1 1
CMBL CYB5R4 0 0 0 176 1 1
CMBL CCDC22 0 0 359 359 1 1
CMBL PPM1A 0 0 0 156 1 1
CMBL RPL23A 0 0 0 234 1 1
CMBL HMGB1 0 0 171 189 1 2
CMBL NAGS 0 0 140 179 1 1
CMBL BACE1 0 0 0 239 1 2
CMBL PGM2L1 0 0 0 187 1 1
CMBL ASAH2B 0 0 109 448 1 1
CMBL ACADS 0 0 0 340 1 1
CMBL PUM1 0 0 0 167 1 1
CMBL RPL23 0 0 0 219 1 1
CMBL RPP38 0 0 195 195 1 1
CMBL ILKAP 0 0 0 156 1 1
CMBL PXMP2 0 0 295 311 1 1
CMBL TIA1 0 0 0 185 1 1
CMBL FLJ22184 0 0 377 377 1 1
CMBL HTATIP2 0 0 108 362 1 1
CMBL AADAC 0 0 0 156 1 1
CMBL SARS 0 0 181 200 1 1
CMBL LRTOMT 0 0 0 152 1 1
CMBL ACSM4 0 0 0 167 1 1
CMBL CXorf36 0 0 0 394 1 1
CMBL HADHB 0 0 0 234 1 1
CMBL MGLL 0 0 0 168 1 1
CMBL CORT 0 0 0 208 1 1
CMBL MSL2 0 0 45 180 1 1
CMBL EPHX3 0 0 0 207 1 1
CMBL OSBPL9 0 0 0 182 1 1
CMBL ADK 0 0 0 155 1 1
CMBL CARKD 0 0 0 441 1 1
CMBL COQ3 0 0 0 202 1 1
CMBL TIAL1 0 0 0 185 1 1
CMBL COCH 0 0 53 182 1 1
CMBL HINT1 0 0 49 289 1 1
CMBL BAZ2B 0 0 0 163 1 1
CMBL LHCGR 0 0 537 537 1 1
CMBL TSPYL4 193 0 0 210 1 1
CMBL BPHL 0 0 64 166 1 1
CMBL SAMD12 0 0 69 323 1 1
CMBL PON2 0 0 193 210 1 1
CMBL IDH2 0 0 42 152 1 1
CMBL CTSD 0 0 0 239 1 2
CMBL PTGR1 0 0 0 204 1 1
CMBL STRADB 0 0 173 357 1 1
CMBL UPP2 0 0 0 553 1 1
CMBL UGT1A7 0 0 0 165 1 1
CMBL UGT1A5 0 0 0 165 1 1
CMBL IL10 0 0 270 270 1 2
CMBL KCNK4 0 0 114 187 1 1
CMBL GSTA5 0 0 0 235 1 1
CMBL BPNT1 0 0 0 304 1 1
CMBL NR1H4 0 0 0 217 1 1
CMBL RCL1 0 0 186 186 1 1
CMBL ZHX3 0 0 173 173 1 1
CMBL SIL1 0 0 0 221 1 1
CMBL NME8 0 0 0 168 1 1
CMBL FTL 0 0 0 155 1 1
CMBL PVRL1 0 0 203 203 1 1
CMBL GPD2 0 0 0 177 1 1
CMBL FKBP2 0 0 0 240 1 1
CMBL AKR7A2 0 0 0 173 1 1
CMBL NFKBIA 0 0 0 252 1 2
CMBL RTCB 0 0 0 177 1 1
CMBL UBE2M 270 0 0 270 1 1
CMBL RPL34 0 0 0 250 1 1
CMBL C12orf5 0 0 0 225 1 1
CMBL C21orf33 0 0 0 301 1 1
CMBL CLPB 0 0 0 298 1 1
CMBL TNRC6A 0 0 46 154 1 1
CMBL ACOT8 0 0 0 181 1 1
CMBL FDFT1 0 0 0 157 1 1
CMBL EEF1E1 0 0 0 194 1 1
CMBL GNB2L1 0 0 0 193 1 1
CMBL MRPL57 0 0 234 234 1 1
CMBL ADH6 0 0 0 382 1 1
CMBL DFFA 0 0 74 216 1 1
CMBL ARHGAP5 0 0 113 259 1 1
CMBL FAH 0 0 113 181 1 1
CMBL NADSYN1 0 0 0 211 1 1
CMBL HPGD 0 0 74 240 1 1
CMBL NDUFA10 0 0 0 157 1 1
CMBL HINT2 0 0 95 360 1 1
CMBL GSTT2B 0 0 119 260 1 1
CMBL FH 0 0 0 173 1 1
CMBL MEMO1 0 0 0 157 1 1
CMBL CFAP44 0 0 81 167 1 1
CMBL L2HGDH 0 0 0 280 1 1
CMBL OSBPL10 0 0 0 151 1 1
CMBL GSTA1 0 0 0 235 1 1
CMBL KIAA1462 0 0 74 170 1 1
CMBL PDF 0 0 0 155 1 1
CMBL PGC 0 0 0 239 1 1
CMBL AGTR1 0 0 415 421 1 1
CMBL TSPAN10 0 0 208 208 1 1
CMBL GAMT 0 0 0 156 1 1
CMBL CRBN 270 0 0 270 1 1
CMBL PDHB 0 0 0 192 1 1
CMBL AGXT 0 0 0 407 1 1
CMBL PPM1K 0 0 0 156 1 1
CMBL GATD3B 0 0 0 301 1 1
CMBL DPYD 0 0 0 167 1 1
CMBL GRAMD4 0 0 194 525 1 1
CMBL MEPCE 270 0 0 270 1 1
CMBL CELF6 0 0 179 218 1 1
CMBL FTCDNL1 0 0 0 254 1 1
CMBL STX2 0 0 51 192 1 1
CMBL PSTK 0 0 421 420 1 1
CMBL CCDC58 0 0 150 298 1 1
CMBL ADH5 0 0 0 382 1 1
CMBL ENSG00000257921 0 0 0 161 1 1
CMBL MTHFR 0 0 0 223 1 1
CMBL GLRX2 0 0 0 387 1 1
CMBL S100A9 0 0 0 163 1 1
CMBL ICMT 0 0 0 218 1 1
CMBL PLEKHA4 270 0 0 270 1 1
CMBL GMFB 0 0 0 240 1 1
CMBL FKBP1C 0 0 0 229 1 1
CMBL IL5 0 0 329 329 1 1
CMBL ACMSD 0 0 0 296 1 1
CMBL FAM173B 0 0 870 876 1 1
CMBL ERAP2 0 0 0 159 1 1
CMBL PPTC7 0 0 0 157 1 1
CMBL GSTP1 0 0 0 235 1 1
CMBL NFKB2 0 0 0 252 1 1
CMBL ACSBG2 0 0 54 282 1 1
CMBL APOB 0 0 0 196 1 2
CMBL TECRL 0 0 193 508 1 1
CMBL RHEBL1 0 0 170 395 1 1
CMBL FHIT 0 0 0 198 1 1
CMBL C1orf116 0 0 193 193 1 1
CMBL GSTM5 0 0 0 235 1 1
CMBL PGAM1 0 0 0 225 1 1
CMBL KRT14 0 0 490 489 1 1
CMBL ESRP2 0 0 120 193 1 1
CMBL FBXO18 0 0 0 158 1 1
CMBL UNC13A 0 0 0 207 1 1
CMBL TRAP1 0 0 0 185 1 2
CMBL PGM1 0 0 0 195 1 1
CMBL ZNF587B 0 0 194 194 1 1
CMBL QTRTD1 0 0 0 177 1 1
CMBL PM20D2 0 0 0 246 1 1
CMBL UGT1A4 0 0 0 165 1 1
CMBL RAVER1 0 0 0 185 1 1
CMBL CBSL 0 0 175 413 1 1
CMBL SRSF4 0 0 0 185 1 1
CMBL MED17 0 0 161 161 1 1
CMBL USP14 270 0 0 270 1 2
CMBL PGM5 0 0 0 195 1 1
CMBL ACADM 0 0 0 383 1 1
CMBL CES1 0 0 217 714 1 1
CMBL FTHL17 0 0 0 155 1 1
CMBL ENSG00000111780 0 0 0 204 1 1
CMBL UGT1A10 0 0 0 165 1 1
CMBL PEBP1 0 0 134 305 1 1
CMBL PON3 0 0 213 230 1 1
CMBL GNL1 0 0 167 492 1 1
CMBL FOXA1 0 0 155 173 1 1
CMBL FEZ2 0 0 193 193 1 1
CMBL TMEM88B 0 0 308 307 1 1
CMBL RBKS 0 0 0 192 1 1
CMBL SLC25A45 0 0 0 159 1 1
CMBL MARCH6 0 0 108 587 1 1
CMBL CSF2 0 0 286 286 1 1
CMBL UGT1A1 0 0 0 165 1 1
CMBL ECHS1 0 0 0 153 1 1
CMBL CES5A 0 0 0 473 1 1
CMBL ROPN1L 0 0 210 523 1 1
CMBL GMFG 0 0 0 240 1 1
CMBL EDF1 0 0 0 252 1 1
CMBL TRHDE 0 0 0 159 1 1
CMBL ABHD15 0 0 287 401 1 1
CMBL AQPEP 0 0 0 159 1 1
CMBL DGKG 0 0 142 330 1 1
CMBL BRDT 0 0 0 175 1 1
CMBL KCNAB2 0 0 0 191 1 1
CMBL PSMD8 0 0 113 202 1 1
CMBL ENSG00000144785 0 0 0 167 1 1
CMBL CACNG8 0 0 203 381 1 1
CMBL GSTM1 0 0 0 235 1 1
CMBL OSGEP 209 0 0 390 1 1
CMBL KCNAB1 0 0 0 191 1 1
CMBL GATM 0 0 0 353 1 1
CMBL HSP90AB1 0 0 0 185 1 2
CMBL RBBP5 0 0 81 179 1 1
CMBL TYMS 0 0 0 220 1 1
CMBL UGT1A9 0 0 0 165 1 1
CMBL SEPP1 0 0 150 605 1 1
CMBL PKHD1L1 0 0 189 189 1 1
CMBL ADH4 0 0 0 382 1 1
CMBL OPN3 0 0 140 296 1 1
CMBL DHODH 0 0 0 154 1 1
CMBL PSMC1 0 0 0 186 1 1
CMBL ENSG00000274276 0 0 174 413 1 1
CMBL PPM1E 0 0 0 156 1 1
CMBL CPA1 0 0 100 345 1 1
CMBL PLEKHF1 0 0 166 309 1 1
CMBL LTB4R 0 0 71 212 1 1
CMBL AHSA1 0 0 0 183 1 1
CMBL GSTA2 0 0 0 235 1 1
CMBL SQRDL 0 0 119 181 1 1
CMBL NOP16 264 0 0 264 1 1
CMBL UGT1A6 0 0 0 165 1 1
CMBL GFPT2 0 0 0 236 1 1
CMBL NME1-NME2 0 0 86 175 1 1
CMBL RNASE4 0 0 0 185 1 1
CMBL TACO1 0 0 218 403 1 1
CMBL STAMBP 0 0 95 342 1 1
CMBL SARS2 0 0 162 182 1 2
CMBL CRY1 0 0 54 389 1 1
CMBL RAPGEF2 0 0 0 303 1 1
CMBL FSIP2 0 0 209 209 1 1
CMBL VDAC3 0 0 0 158 1 1
CMBL COMT 0 0 0 152 1 1
CMBL ENAH 0 0 107 264 1 1
CMBL HFM1 0 0 0 165 1 1
CMBL MED20 0 0 170 169 1 1
CMBL ING2 0 0 107 161 1 1
CMBL SRXN1 0 0 0 183 1 1
CMBL ALDH6A1 0 0 0 267 1 1
CMBL GTPBP3 0 0 0 299 1 1
CMBL SUOX 0 0 0 276 1 1
CMBL ECH1 178 0 0 259 1 1
CMBL FIBIN 0 0 186 536 1 1
CMBL COQ6 0 0 0 201 1 1
CMBL DAO 0 0 0 164 1 2
CMBL CPA2 0 0 0 163 1 1
CMBL CHML 0 0 112 218 1 1
CMBL TRIT1 0 0 49 213 1 1
CMBL ANPEP 0 0 0 180 1 1
CMBL HIST1H2BJ 154 0 0 153 1 1
CMBL H6PD 0 0 55 206 1 1
CMBL MDH2 0 0 0 178 1 1
CMBL MGST1 0 0 95 297 1 1
CMBL C11orf73 0 0 0 225 1 1
CMBL ASPN 0 0 95 304 1 1
CMBL GLRX 0 0 138 367 1 1
CMBL ATP5H 0 0 0 158 1 1
CMBL MYBPC1 0 0 141 501 1 1
CMBL HEXIM1 270 0 0 270 1 1
CMBL PUS3 0 0 188 255 1 1
CMBL DCP2 0 0 0 184 1 1
CMBL PIP4K2B 0 0 0 238 1 1
CMBL ENSG00000258674 0 0 0 198 1 1
CMBL PGA3 0 0 0 239 1 1
CMBL GSTA3 0 0 0 235 1 1
CMBL ZFYVE1 0 0 170 169 1 2
CMBL HINT3 0 0 0 198 1 1
CMBL CTCF 209 0 0 209 1 1
CMBL GSTM4 0 0 0 235 1 1
CMBL FKBP6 0 0 0 271 1 1
CMBL GSTZ1 0 0 124 270 1 1
CMBL JPH1 0 0 268 268 1 1
CMBL CPA5 0 0 0 163 1 1
CMBL TDRD12 0 0 204 252 1 1
CMBL AKNAD1 0 0 295 424 1 1
CMBL SLC25A13 0 0 0 206 1 1
CMBL LOC388210 0 0 0 179 1 1
CMBL PPM1D 0 0 0 156 1 1
CMBL VDAC1 0 0 46 171 1 2
CMBL GMPR2 0 0 0 362 1 1
CMBL TMOD3 0 0 0 175 1 1
CMBL PARN 0 0 0 197 1 1
CMBL LSM6 0 0 170 243 1 1
CMBL NEU1 0 0 0 256 1 1
CMBL FTCD 0 0 0 508 1 1
CMBL PARM1 0 0 165 318 1 1
CMBL MCEE 0 0 0 203 1 1
CMBL HSPE1 0 0 0 312 1 1
CMBL GLO1 0 0 0 203 1 1
CMBL SLC30A9 0 0 0 247 1 1
CMBL ZBTB8OS 0 0 0 210 1 1
CMBL PCK2 0 0 0 235 1 1
CMBL CRYZ 0 0 73 160 1 1
CMBL HSP90AA1 0 0 0 185 1 2
CMBL ZNF514 209 0 0 209 1 1
CMBL RPEL1 0 0 0 218 1 1
CMBL HPGDS 0 0 42 236 1 1
CMBL MBL2 0 0 167 220 1 1
CMBL ANKRD2 0 0 165 292 1 1
CMBL ACAA2 0 0 0 387 1 1
CMBL BACE2 0 0 0 239 1 1
CMBL CELA3B 0 0 123 151 1 1
CMBL ACSBG1 0 0 0 317 1 1
CMBL FTMT 0 0 0 155 1 1
CMBL UGT1A3 0 0 0 165 1 1
CMBL LOC728763 0 0 0 212 1 1
CMBL ADH1B 0 0 95 416 1 1
CMBL DMC1 0 0 0 189 1 1
CMBL ADH7 0 0 0 382 1 1
CMBL ACAD8 0 0 0 209 1 1
CMBL TRIM31 0 0 162 181 1 1
CMBL ADAD1 0 0 150 235 1 1
CMBL ACSM5 0 0 0 167 1 1
CMBL SPR 0 0 0 283 1 1
CMBL NDUFAF6 0 0 0 157 1 1
CMBL MOCS2 0 0 0 231 1 1
CMBL F13B 0 0 0 286 1 1
CMBL HNRNPM 0 0 0 185 1 1
CMBL SLC25A48 0 0 0 159 1 1
CMBL PGAM2 0 0 107 278 1 1
CMBL TMEM241 0 0 274 274 1 1
CMBL SORD 0 0 180 197 1 1
CMBL FKBP14 0 0 167 340 1 1
CMBL EIF3K 0 0 0 258 1 1
CMBL UGT1A8 0 0 0 165 1 1
CMBL MOB2 398 0 0 411 1 1
CMBL PUM2 0 0 0 167 1 1
CMBL CSTF3 0 0 0 523 1 1
CMBL CYB5B 0 0 150 305 1 1
CMBL MAT2A 0 0 58 229 1 1
CMBL NINJ2 0 0 160 159 1 1
CMBL PPM1F 0 0 0 156 1 1
CMBL PDXDC1 0 0 211 211 1 1
CMBL SPATS2L 0 0 181 181 1 1
CMBL PP2D1 0 0 0 156 1 1
CMBL FKBP3 0 0 0 229 1 1
CMBL APOL6 0 0 155 203 1 1
CMBL PAF1 0 0 156 155 1 1
CMBL COX17 0 0 0 185 1 1
CMBL WDR31 0 0 0 193 1 1
CMBL BRD3 0 0 0 175 1 1
CMBL TMEM14B 0 0 0 186 1 1
CMBL NR2F2 0 0 49 184 1 1
CMBL MGST3 0 0 90 309 1 1
CMBL SEPSECS 0 0 369 382 1 1
CMBL SLC22A18 0 0 0 169 1 1
CMBL MALSU1 0 0 0 259 1 1
CMBL COX15 0 0 0 241 1 1
CMBL ARSI 0 0 74 244 1 1
CMBL SNCA 246 0 0 245 1 2
CMBL CHEK1 0 0 0 238 1 2
CMBL KMO 0 0 120 444 1 1
CMBL ILDR1 0 0 160 159 1 1
CMBL SRF 0 0 47 247 1 1
CMBL HAO2 0 0 0 196 1 1
CMBL GSTA4 0 0 0 343 1 1
CMBL HLA-DRB1 0 0 158 157 1 1
CMBL SPSB4 0 0 193 193 1 1
CMBL PPM1L 0 0 0 156 1 1
CMBL PDP1 0 0 0 168 1 1
CMBL RBMS2 0 0 0 185 1 1
CMBL CSNK1A1L 0 0 245 244 1 1
CMBL SQLE 0 0 0 201 1 1
CMBL LIX1L 0 0 0 190 1 1
CMBL AIFM2 0 0 0 265 1 1
CMBL PAICS 0 0 0 189 1 1
CMBL TREH 0 0 134 313 1 1
CMBL ENSG00000274068 0 0 0 217 1 1
CMBL AKR1B1 0 0 193 243 1 1
CMBL GPHN 0 0 0 159 1 1
CMBL ENSG00000266953 0 0 0 170 1 1
CMBL DICER1 0 0 81 173 1 1
CMBL ACAD10 0 0 0 237 1 1
CMBL ACSF3 0 0 66 404 1 1
CMBL NDST4 0 0 161 345 1 1
CMBL PCBP2 0 0 103 164 1 1
CMBL RBM47 0 0 142 275 1 1
CMBL HPCAL4 0 0 234 400 1 1
CMBL NAP1L5 209 0 0 209 1 1
CMBL HSPE1-MOB4 0 0 0 312 1 1
CMBL PPP4R2 0 0 171 414 1 1
CMBL VARS 0 0 46 222 1 1
CMBL NDUFAB1 0 0 96 221 1 1
CMBL HSP90B1 0 0 0 185 1 1
CMBL TRA2B 0 0 95 153 1 1
CMBL SNRNP70 0 0 0 185 1 1
CMBL CYP3A5 0 0 60 181 1 1
CMBL GMPR 0 0 0 362 1 1
CMBL MEST 0 0 0 207 1 1
CMBL OTUB1 0 0 134 152 1 1
CMBL ACP6 0 0 181 199 1 1
CMBL GPX4 0 0 81 155 1 2
CMBL KIAA2022 0 0 232 231 1 1
CMBL FKBP1A 0 0 0 229 1 2
CMBL GDPD3 0 0 0 160 1 1
CMBL PPIL6 0 0 0 158 1 1
CMBL XPNPEP2 0 0 0 152 1 1
CMBL COX6A2 0 0 0 204 1 1
CMBL UPP1 0 0 0 553 1 1
CMBL KCTD9 0 0 0 154 1 1
CMBL IMPDH1 0 0 0 362 1 1
CMBL HMGCS2 0 0 0 151 1 1
CMBL BLMH 0 0 48 612 1 1
CMBL EXOC3L4 0 0 0 237 1 1
CMBL FKBP4 0 0 46 338 1 1
CMBL OLAH 0 0 0 284 1 1
CMBL BMP7 0 0 193 193 1 1
CMBL IDH1 0 0 0 151 1 1
CMBL RPL6 248 0 0 260 1 1
CMBL BOLA2B 0 0 0 207 1 1
CMBL NFIL3 0 0 61 317 1 1
CMBL FKBP5 0 0 90 467 1 1
CMBL EREG 0 0 539 539 1 1
CMBL PFDN5 0 0 0 426 1 1
CMBL CYP3A4 0 0 0 165 1 1
CMBL GTPBP8 0 0 0 233 1 1
CMBL ACAA1 0 0 0 338 1 1
CMBL H2AFX 270 0 391 536 1 1
CMBL PPM1G 0 0 0 156 1 1
CMBL ALB 0 0 134 155 1 2
CMBL ENPEP 0 0 0 159 1 1
CMBL TMEM14A 0 0 0 186 1 1
CMBL IL4 0 0 270 270 1 1
CMBL TECR 0 0 0 415 1 1
CMBL BPGM 0 0 0 225 1 1
CMBL CRY2 0 0 60 396 1 1
CMBL ZNF445 0 0 261 261 1 1
CMBL CELA2A 0 0 57 211 1 1
CMBL MBLAC2 209 0 0 268 1 1
CMBL ADH1C 0 0 0 382 1 1
CMBL RBMS3 0 0 0 185 1 1
CMBL CRYL1 0 0 0 293 1 1
CMBL AGR2 114 0 211 271 1 1
CMBL BRD4 0 0 0 175 1 2
CMBL SRSF1 0 0 0 185 1 1
CMBL PYROXD2 0 0 0 180 1 1
CMBL ELAVL2 0 0 122 154 1 1
CMBL NR2F1 0 0 56 171 1 1
CMBL LRRC17 0 0 184 183 1 1
CMBL IMPDH2 0 0 0 362 1 1
CMBL RBMS1 0 0 0 185 1 1
CMBL SRSF6 0 0 0 185 1 1
CMBL DDAH2 0 0 0 336 1 1
CMBL VDAC2 0 0 0 158 1 1
CMBL CES2 0 0 107 510 1 1
CMBL MYEF2 0 0 0 185 1 1
CMBL TRIM24 209 0 0 227 1 1
CMBL MSL3 0 0 160 159 1 1
CMBL MRPL13 0 0 0 181 1 1
CMBL GART 0 0 0 388 1 1
CMBL OPLAH 0 0 0 286 1 1
CMBL CSTF2T 0 0 0 185 1 1
CMBL MARS 0 0 0 194 1 1
CMBL AHSA2 0 0 0 183 1 1
CMBL OSGEPL1 0 0 0 468 1 1
CMBL ADH1A 0 0 0 382 1 1
CMBL CPB2 0 0 0 167 1 1
CMBL QPCT 193 0 0 193 1 1
CMBL SLC2A2 0 0 0 170 1 1
CMBL EXO1 0 0 103 195 1 1
CMBL HSPBP1 0 0 0 221 1 1
CMBL CTSE 0 0 0 239 1 1
CMBL QTRT1 0 0 0 177 1 1
CMBL PARK7 0 0 61 247 1 2
CMBL AMMECR1L 0 0 0 218 1 1
CMBL ACAD9 0 0 45 318 1 1
CMBL CTNND2 0 0 171 348 1 1
CMBL KIF20B 151 0 0 157 1 1
CMBL FKBP11 0 0 0 240 1 1
CMBL CYP3A7 0 0 90 207 1 1
CMBL UNC13D 0 0 95 292 1 1
CMBL LNPEP 0 0 0 159 1 1
CMBL IYD 0 0 0 186 1 1
CMBL CEL 0 0 87 163 1 1
CMBL BTC 0 0 641 641 1 1
CMBL BOLA2 0 0 0 207 1 1
CMBL AMMECR1 0 0 0 218 1 1
CMBL SMPDL3A 0 0 165 695 1 1
CMBL LSG1 0 0 0 152 1 1
CMBL ALDH8A1 0 0 0 189 1 1
CMBL FKBP7 0 0 0 240 1 1
CMBL AREG 0 0 609 609 1 1
CMBL SSR1 0 0 0 213 1 1
CMBL PIP4K2A 0 0 218 542 1 1
CMBL RALGDS 0 0 210 224 1 1
CMBL PGA5 0 0 0 239 1 1
CMBL C9orf114 0 0 243 242 1 1
CMBL PPIG 0 0 0 163 1 1
CMBL PCK1 0 0 0 216 1 1
CMBL LARP7 270 0 0 296 1 1
CMBL GDPD1 0 0 280 432 1 1
CMBL LHFPL5 0 0 166 165 1 1
CMBL SMPDL3B 0 0 60 456 1 1
CMBL HGD 0 0 0 165 1 1
CMBL APOA1BP 0 0 0 198 1 1
CMBL CELA1 0 0 0 202 1 1
CMBL FKBP1B 0 0 0 229 1 1
CMBL TAB1 0 0 0 156 1 1
CMBL MTFMT 0 0 0 177 1 1
CMBL MOB4 0 0 179 179 1 1
CMBL TRNT1 0 0 236 236 1 1
CMBL NAPSA 0 0 0 239 1 1
CMBL YJEFN3 0 0 0 198 1 1
CMBL EMC4 270 0 0 270 1 1
CMBL TSFM 0 0 45 184 1 1
CMBL TMEM14E 0 0 0 186 1 1
CMBL SLC25A20 0 0 0 159 1 1
CMBL DPEP2 0 0 203 419 1 1
CMBL PHLPP1 0 0 95 186 1 2
CMBL GSTM3 0 0 0 235 1 1
CMBL WRNIP1 0 0 0 227 1 1
CMBL DERA 0 0 322 321 1 1
CMBL PHYH 0 0 113 159 1 1
CMBL RAB18 0 0 134 227 1 1
CMBL ATIC 71 0 0 245 1 2
CMBL GAPDH 0 0 142 161 1 2
CMBL AKR7A3 0 0 0 173 1 1
CMBL APTX 0 0 0 256 1 1
CMBL ENO1 0 0 136 178 1 1
CMBL HYAL2 0 0 0 186 1 1
CMBL CPA4 0 0 0 163 1 1
CMBL KHDRBS2 0 0 125 185 1 1
CMBL PGAM4 0 0 0 225 1 1
CMBL FKBP8 0 0 0 271 1 1
CMBL GRHPR 0 0 0 155 1 1
CMBL PPID 0 0 97 250 1 1
CMBL UROD 0 0 0 238 1 1
CMBL DDO 0 0 0 164 1 1
CMBL PDXK 0 0 0 189 1 1
CMBL TMOD2 0 0 161 379 1 1
CMBL PCTP 0 0 0 162 1 1
CMBL AKR1B10 0 0 95 151 1 1
CMBL BRINP1 0 0 54 539 1 1
CMBL APOA4 0 0 0 165 1 1
CMBL HSD11B1 0 0 0 156 1 1
CMBL NPEPPS 0 0 0 159 1 1
CMBL GLOD4 0 0 0 191 1 1
CMBL MGMT 0 0 0 171 1 2
CMBL CS 0 0 0 169 1 1
CMBL NKTR 0 0 45 166 1 1
CMBL GRPEL1 0 0 0 163 1 1
CMBL UNC13C 0 0 154 523 1 1
CMBL MCCC2 274 0 0 274 1 1
CMBL KCNAB3 0 0 0 191 1 1
CMBL ABAT 0 0 57 331 1 1
CMBL ETFA 0 0 0 175 1 1
CMBL PDP2 0 0 0 168 1 1
CMBL CSDC2 0 0 280 559 1 1
CMBL STARD7 0 0 60 331 1 1
CMBL EPHX4 0 0 0 207 1 1
CMBL FKBP15 0 0 0 239 1 1
CMBL OPA3 0 0 156 155 1 1
CMBL ANXA11 0 0 67 228 1 1
CMBL CELA2B 0 0 95 243 1 1
CMBL PIPOX 0 0 0 193 1 1
CMBL SPATA20 0 0 0 281 1 1
CMBL RPL13A 0 0 0 181 1 1
CMBL EPHX2 0 0 0 411 1 1
CMBL VAT1 0 0 0 159 1 1
CMBL SRSF9 0 0 0 185 1 1
CMBL TMEM254 0 0 125 179 1 1
CMBL SPRR4 0 0 230 229 1 1
CMBL RAD51C 0 0 0 189 1 1
CMBL BRD2 0 0 0 175 1 1
CMBL NAP1L1 264 0 0 264 1 1
CMBL HHATL 0 0 262 330 1 1
CMBL FOLR1 0 0 151 150 1 1
CMBL TRA2A 274 0 0 302 1 1
CMBL CCT5 0 0 112 288 1 1
CMBL BAG3 270 0 0 315 1 2
CMBL SIRT5 0 0 67 193 1 1
CMBL NDST3 0 0 0 252 1 1
CMBL BOLA3 0 0 0 414 1 1
CMBL SELENBP1 0 0 108 278 1 1
CMBL CHM 0 0 0 155 1 2
CMBL KIAA1429 270 0 0 270 1 1
CMBL TSPO2 0 0 0 183 1 1
CMBL RETSAT 0 0 0 180 1 1
CMBL ZHX1 0 0 194 194 1 1
CMBL C7 0 0 54 237 1 1
CMBL DPEP3 0 0 0 301 1 1
CMBL THOP1 0 0 150 398 1 1
CMBL LYPD6B 0 0 220 220 1 1
CMBL TMEM14C 0 0 0 186 1 1
CMBL CCBE1 0 0 126 260 1 1
CMBL ACSL5 0 0 113 241 1 1
CMBL ERAP1 0 0 0 159 1 1
CMBL MCCC1 274 0 0 274 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0016787 Molecular Function hydrolase activity enables TAS
GO:0006805 Biological Process xenobiotic metabolic process involved_in TAS
GO:0005829 Cellular Component cytosol located_in TAS
GO:0070062 Cellular Component extracellular exosome located_in HDA
Pathways
Name DB ID
Metabolism Reactome R-HSA-1430728
Biological oxidations Reactome R-HSA-211859
Phase I - Functionalization of compounds Reactome R-HSA-211945
Transcripts
Accession Version MolecularType Name NCBI Comments
NM_138809 4 mRNA None NC_000005 Reference
XM_047416714 1 mRNA transcript variant X1 NC_000005 Reference
XM_047416716 1 mRNA transcript variant X3 NC_000005 Reference
XM_047416717 1 mRNA transcript variant X4 NC_000005 Reference
XM_047416715 1 mRNA transcript variant X2 NC_000005 Reference
XM_047416718 1 mRNA transcript variant X5 NC_000005 Reference