HAdb 2.0 is available now!

CTSK

cathepsin K
General Information
Name cathepsin K
Alias
  • cathepsin K
  • cathepsin O
  • cathepsin O1
  • cathepsin O2
  • cathepsin X
Gene_family Cathepsins
organism Homo sapiens
entrez_id 1513
location 1q21.3
transcript_count 1
exon_count 8
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. [provided by RefSeq, Apr 2013]
    Stringdb Cathepsin K; Closely involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation; Cathepsins
    nextProt Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen (PubMed:11082042).
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
CTSK BioGRID NF1 GeneID BioGRID Negative Genetic
CTSK BioGRID S GeneID BioGRID Biochemical Activity
CTSK BioGRID POTEF GeneID BioGRID Affinity Capture-MS
CTSK BioGRID ARK2N GeneID BioGRID Affinity Capture-MS
CTSK BioGRID TINAGL1 GeneID BioGRID Affinity Capture-MS
CTSK BioGRID ERBIN GeneID BioGRID Affinity Capture-MS
CTSK BioGRID ARID4B GeneID BioGRID Affinity Capture-MS
CTSK BioGRID CTSV GeneID BioGRID Affinity Capture-MS
CTSK BioGRID CTSL GeneID BioGRID Affinity Capture-MS
CTSK BioGRID DDX39A GeneID BioGRID Affinity Capture-RNA
CTSK BioGRID CGAS GeneID BioGRID Affinity Capture-MS
CTSK BioGRID LIG4 GeneID BioGRID Two-hybrid
CTSK Protein SERPINB13 GeneID HPRD
CTSK Protein SERPINB3 GeneID HPRD
CTSK Protein KNG1 GeneID HPRD
CTSK Protein SPARC GeneID HPRD
CTSK Protein FGFR3 GeneID HPRD
CTSK BioGRID SERPINB3 GeneID BioGRID Reconstituted Complex
CTSK BioGRID FGFR3 GeneID BioGRID Two-hybrid
StringDB
A B experiments database textmining combined score hadb nhadb
CTSK UBE2M 0 0 0 160 1 1
CTSK FERMT3 0 0 151 169 1 1
CTSK KIT 0 0 274 302 1 2
CTSK TXNDC2 0 0 0 194 1 1
CTSK CORO1B 0 0 0 165 1 1
CTSK TNFRSF11A 0 0 662 668 1 1
CTSK SNTG1 0 0 155 154 1 1
CTSK FPR1 0 0 388 388 1 1
CTSK BMPR1A 0 0 184 216 1 1
CTSK GAPDHS 0 0 0 206 1 1
CTSK CD200 0 0 158 177 1 1
CTSK MMP11 0 0 82 371 1 1
CTSK NME8 0 0 0 222 1 1
CTSK NFATC1 0 0 870 892 1 2
CTSK FOSL2 0 0 398 413 1 1
CTSK IL10 0 0 340 340 1 2
CTSK FGFR4 0 0 66 163 1 1
CTSK IGF2 0 0 150 171 1 1
CTSK CCL3 0 0 271 271 1 1
CTSK CTSG 0 0 412 463 1 1
CTSK ENG 0 0 134 187 1 2
CTSK ELANE 0 0 324 323 1 1
CTSK PKN3 0 0 96 194 1 1
CTSK ATP6AP1 0 0 233 289 1 1
CTSK TBP 0 0 103 159 1 1
CTSK FN1 0 0 451 476 1 2
CTSK CTNNA2 0 0 67 233 1 1
CTSK NONO 0 0 234 234 1 1
CTSK MMP13 0 300 672 766 1 2
CTSK GDE1 0 0 66 159 1 1
CTSK TYRP1 0 0 306 306 1 1
CTSK MATN3 0 0 91 151 1 1
CTSK TIMP2 0 0 321 373 1 1
CTSK FAM20C 0 0 139 182 1 1
CTSK ERP27 0 0 0 178 1 1
CTSK UBC 0 0 82 198 1 2
CTSK SPHK1 0 0 204 277 1 2
CTSK EFNA2 0 0 142 164 1 1
CTSK NRTN 0 0 0 426 1 1
CTSK NEURL1 0 0 0 183 1 1
CTSK PPT1 0 0 66 233 1 1
CTSK KDELR2 0 0 46 162 1 1
CTSK PDIA5 0 0 0 178 1 1
CTSK ENSG00000241489 0 0 0 156 1 1
CTSK COX7A1 0 0 0 156 1 1
CTSK ATP4A 0 0 466 475 1 1
CTSK ELN 0 0 519 529 1 1
CTSK C1QA 0 0 108 227 1 1
CTSK KHK 0 0 0 252 1 1
CTSK ESR1 0 0 405 414 1 2
CTSK IFNB1 0 0 204 204 1 1
CTSK TXNDC5 0 0 0 178 1 1
CTSK JTB 0 0 0 231 1 1
CTSK ADAMTS14 0 0 134 196 1 1
CTSK FLT4 0 0 66 163 1 1
CTSK MAPK11 0 0 46 162 1 1
CTSK FGF23 0 0 392 403 1 1
CTSK DNAJC10 0 0 0 179 1 1
CTSK MAPT 0 0 54 160 1 2
CTSK AP1S1 0 0 66 210 1 1
CTSK HLA-DPA1 0 900 74 905 1 1
CTSK THBS1 0 0 209 248 1 1
CTSK IL2 0 0 169 169 1 1
CTSK ANXA1 0 0 82 225 1 1
CTSK ITGA2 0 0 154 153 1 1
CTSK VSIG4 0 0 81 173 1 1
CTSK DLX5 0 0 243 261 1 1
CTSK COL9A1 0 0 123 152 1 1
CTSK CSPG4 0 0 66 201 1 1
CTSK HLA-DRA 0 900 60 901 1 1
CTSK ITPKA 0 0 53 263 1 1
CTSK RARRES1 0 0 66 191 1 1
CTSK SAR1B 0 0 74 171 1 1
CTSK CAPG 0 0 0 199 1 1
CTSK MMP24 0 0 103 358 1 1
CTSK EDC3 0 0 0 165 1 1
CTSK COL12A1 0 0 151 221 1 1
CTSK CA1 0 0 93 193 1 1
CTSK PKN2 0 0 134 168 1 1
CTSK LILRB4 0 0 150 168 1 1
CTSK ITGB2 0 0 439 466 1 1
CTSK SVIL 0 0 0 499 1 1
CTSK PTH 0 0 681 702 1 1
CTSK CORO1C 0 0 108 223 1 1
CTSK TKT 0 0 0 213 1 1
CTSK LNX2 0 0 48 174 1 1
CTSK PGA4 0 0 0 267 1 1
CTSK PFN1 0 0 150 227 1 1
CTSK GUSB 0 0 166 225 1 1
CTSK CDKN2A 0 0 458 617 1 2
CTSK CXCL16 0 0 113 184 1 1
CTSK GSK3B 0 0 112 201 1 2
CTSK MRC1 0 0 142 192 1 1
CTSK KRT7 0 0 371 371 1 1
CTSK PDILT 0 0 0 178 1 1
CTSK TKTL2 0 0 0 213 1 1
CTSK PDIA4 0 0 0 211 1 1
CTSK TG 0 0 184 231 1 1
CTSK TWIST2 0 0 124 169 1 1
CTSK CEBPB 0 0 123 173 1 2
CTSK ATG16L1 0 0 122 182 1 2
CTSK ENPP1 0 0 134 184 1 1
CTSK CASP3 0 0 323 335 1 2
CTSK PDIA6 0 0 0 294 1 1
CTSK PTGS2 0 0 293 329 1 2
CTSK ADAM21 0 0 124 151 1 1
CTSK CTSZ 0 0 502 310 1 1
CTSK REL 0 0 147 159 1 2
CTSK COL6A2 0 0 167 259 1 1
CTSK CYBB 0 0 142 199 1 2
CTSK SACS 0 0 0 190 1 1
CTSK DNPH1 0 0 0 260 1 1
CTSK IHH 0 0 293 293 1 1
CTSK CTSS 0 300 561 476 1 1
CTSK ACE 0 0 263 272 1 1
CTSK ASAH1 0 0 52 218 1 1
CTSK IL13 0 0 212 212 1 2
CTSK REN 0 0 123 329 1 1
CTSK TMPRSS15 0 0 96 189 1 1
CTSK TSC2 0 0 154 153 1 2
CTSK MSX2 0 0 210 238 1 1
CTSK CLCN7 0 0 681 689 1 1
CTSK GLRX 0 0 0 161 1 1
CTSK AP1S3 0 0 0 207 1 1
CTSK HMOX1 0 0 279 318 1 2
CTSK SLC17A7 0 0 0 177 1 1
CTSK MMP12 0 300 458 634 1 1
CTSK ANPEP 0 0 113 219 1 1
CTSK MITF 0 0 565 586 1 2
CTSK NFATC2 0 0 285 290 1 1
CTSK IQGAP3 0 0 0 155 1 1
CTSK FLT1 0 0 141 174 1 1
CTSK NPNT 0 0 0 266 1 1
CTSK LGALS3 0 0 171 242 1 2
CTSK EIF2AK3 0 0 291 290 1 2
CTSK TREML1 0 0 67 160 1 1
CTSK PCSK9 0 0 0 222 1 1
CTSK DPY30 0 0 0 467 1 1
CTSK CD47 0 0 122 273 1 2
CTSK AP3M1 0 0 134 267 1 1
CTSK ADAM12 0 0 203 227 1 1
CTSK SRC 0 0 560 582 1 2
CTSK TLR9 0 0 330 332 1 2
CTSK ATP6V1A 0 0 166 206 1 1
CTSK IGF2R 0 0 181 190 1 1
CTSK IL6ST 0 0 136 173 1 1
CTSK GPRC6A 0 0 95 197 1 1
CTSK CTSC 0 0 469 193 1 1
CTSK TSPAN5 0 0 70 167 1 1
CTSK CR2 0 0 296 296 1 1
CTSK NOTCH2NL 0 0 0 217 1 1
CTSK AP1S2 0 0 0 189 1 1
CTSK ID2 0 0 76 168 1 1
CTSK IL11 0 0 367 367 1 1
CTSK NDUFB6 0 0 0 196 1 1
CTSK NID1 0 0 150 199 1 1
CTSK SPON1 0 0 167 185 1 1
CTSK MMP23B 0 0 112 216 1 1
CTSK CXCL10 0 0 181 201 1 2
CTSK COL1A2 0 0 457 555 1 1
CTSK RXFP1 0 0 57 163 1 1
CTSK IKBKB 0 0 261 284 1 2
CTSK COL6A1 0 0 206 323 1 1
CTSK KLF4 0 0 66 167 1 2
CTSK FGFR1 0 0 181 218 1 1
CTSK NEURL1B 0 0 0 183 1 1
CTSK XIAP 0 600 49 603 1 2
CTSK SERPINB6 0 0 0 234 1 1
CTSK RUNX2 0 0 681 714 1 2
CTSK FMOD 0 0 218 371 1 1
CTSK UBLCP1 0 0 0 150 1 1
CTSK AKT1 0 0 469 493 1 2
CTSK TGFB2 0 0 240 318 1 1
CTSK PPARG 0 0 348 372 1 2
CTSK RRM1 0 0 0 158 1 1
CTSK CD4 0 0 285 324 1 2
CTSK ATF4 0 0 195 229 1 2
CTSK PTHLH 0 0 556 572 1 1
CTSK UBA5 0 0 0 244 1 1
CTSK DIAPH3 0 0 108 163 1 1
CTSK ENAM 0 0 158 164 1 1
CTSK TNF 0 0 556 575 1 2
CTSK MSX1 0 0 112 172 1 1
CTSK WISP1 0 0 143 411 1 1
CTSK VDR 0 0 246 263 1 2
CTSK ZFP36L2 0 0 0 174 1 1
CTSK IL1RN 0 0 137 158 1 1
CTSK MMP3 0 300 505 677 1 1
CTSK DCT 0 0 326 325 1 1
CTSK SERPINB13 213 800 160 872 1 1
CTSK MMP25 0 0 155 328 1 1
CTSK ANKRD1 0 0 49 174 1 1
CTSK SLC4A2 0 0 218 218 1 1
CTSK IFNL1 0 0 306 306 1 1
CTSK LIPG 0 0 45 210 1 1
CTSK PLOD2 0 0 134 237 1 1
CTSK THBS2 0 0 210 287 1 1
CTSK FABP1 0 0 66 167 1 1
CTSK MEP1A 0 0 124 184 1 1
CTSK MMP27 0 0 0 312 1 1
CTSK NFKB2 0 0 183 213 1 1
CTSK IL34 0 0 192 212 1 1
CTSK ATG4B 0 0 150 236 1 2
CTSK ATP12A 0 0 483 487 1 1
CTSK IGFBP6 0 0 147 180 1 1
CTSK MMP8 0 0 426 465 1 1
CTSK GPNMB 0 0 391 466 1 1
CTSK SLC17A8 0 0 0 158 1 1
CTSK CD9 0 0 165 183 1 1
CTSK RAB7A 0 0 234 267 1 2
CTSK C18orf25 353 0 0 353 1 1
CTSK DVL2 0 0 186 206 1 2
CTSK HDAC7 0 0 112 152 1 1
CTSK LYL1 0 0 0 167 1 1
CTSK AHR 0 0 439 439 1 2
CTSK SERPINE1 0 0 218 272 1 1
CTSK IDUA 0 0 202 225 1 1
CTSK ECEL1 0 0 94 157 1 1
CTSK PGC 0 0 0 267 1 1
CTSK RPS6KB1 0 0 165 171 1 2
CTSK TSPAN10 0 0 62 277 1 1
CTSK HSPA9 0 0 0 258 1 1
CTSK CBL 0 0 218 218 1 1
CTSK UBL4A 0 0 0 163 1 1
CTSK MMP19 0 0 218 313 1 1
CTSK LOX 0 0 270 345 1 2
CTSK HMSD 0 0 0 234 1 1
CTSK EGFL7 0 0 0 160 1 1
CTSK MXRA5 0 0 87 182 1 1
CTSK HGF 0 0 171 202 1 2
CTSK ADAMTS3 0 0 324 353 1 1
CTSK RASA1 0 0 0 250 1 1
CTSK BMPR2 0 0 113 153 1 1
CTSK GLB1L 0 0 181 267 1 1
CTSK PCSK2 0 0 0 156 1 1
CTSK WNT10B 0 0 288 289 1 1
CTSK CTLA4 0 0 154 153 1 2
CTSK MLANA 0 0 517 517 1 1
CTSK OCSTAMP 0 0 685 771 1 1
CTSK BCL2 0 600 0 603 1 2
CTSK HPRT1 0 0 292 292 1 1
CTSK FBLN1 0 0 140 246 1 1
CTSK SERPINB11 0 0 53 408 1 1
CTSK MYLK 0 0 82 167 1 1
CTSK SERPINB1 0 0 81 418 1 1
CTSK LRRC47 0 0 0 158 1 1
CTSK SLC17A6 0 0 0 191 1 1
CTSK LGALS1 0 0 66 151 1 1
CTSK SVEP1 0 0 69 157 1 1
CTSK NOTCH3 0 0 69 168 1 1
CTSK OLFML2B 0 0 151 297 1 1
CTSK ITGB1 0 0 204 222 1 1
CTSK FAP 0 0 133 291 1 2
CTSK MFAP5 0 0 107 223 1 1
CTSK DSPP 0 0 181 181 1 1
CTSK LEPR 0 0 141 159 1 1
CTSK KNG1 213 0 195 339 1 1
CTSK CASP8 0 0 163 177 1 2
CTSK SPAST 0 0 0 181 1 1
CTSK IL1A 0 0 310 309 1 1
CTSK SPCS3 0 0 0 198 1 1
CTSK DCTN1 0 0 46 218 1 1
CTSK DPP4 0 0 229 274 1 1
CTSK BSG 0 0 158 157 1 1
CTSK PLG 0 0 269 269 1 1
CTSK MXRA8 0 0 0 223 1 1
CTSK TPM4 0 0 54 190 1 1
CTSK BMP7 0 0 308 307 1 1
CTSK HYOU1 0 0 81 156 1 1
CTSK MATN1 0 0 108 219 1 1
CTSK GLI2 0 0 134 194 1 2
CTSK HLA-DQA1 0 900 93 905 1 1
CTSK ADAMTS2 0 0 155 223 1 1
CTSK ENO2 0 0 193 236 1 1
CTSK THNSL1 0 0 46 194 1 1
CTSK CPA3 0 0 62 197 1 1
CTSK RUVBL1 0 0 0 156 1 1
CTSK ADIPOQ 0 0 233 316 1 2
CTSK VIM 0 0 108 256 1 2
CTSK GNPTAB 0 0 323 598 1 1
CTSK CSK 0 0 287 300 1 1
CTSK LYG2 0 0 0 194 1 1
CTSK CTGF 0 0 261 277 1 1
CTSK NR3C1 0 0 107 175 1 1
CTSK PDGFA 0 0 181 181 1 1
CTSK PTGER4 0 0 150 171 1 1
CTSK SCIN 0 0 86 203 1 1
CTSK AMBN 0 0 229 238 1 1
CTSK PXN 0 0 181 181 1 1
CTSK HIST2H3PS2 0 0 159 172 1 1
CTSK RPTOR 0 0 96 186 1 2
CTSK NES 0 0 155 172 1 2
CTSK MRC2 0 0 278 371 1 1
CTSK ACVR1 0 0 96 172 1 1
CTSK COL5A1 0 0 202 243 1 1
CTSK IL12RB2 0 0 46 219 1 1
CTSK ENSG00000273554 0 0 0 162 1 1
CTSK TMX1 0 0 0 156 1 1
CTSK SETD7 0 0 0 426 1 1
CTSK IL17A 0 0 418 418 1 2
CTSK ETS1 0 0 92 154 1 1
CTSK POMC 0 0 113 157 1 1
CTSK CASP9 0 0 137 211 1 2
CTSK TLR7 0 900 155 914 1 2
CTSK IL13RA2 0 0 98 189 1 1
CTSK TAF8 0 0 154 153 1 1
CTSK PTDSS1 0 0 44 204 1 1
CTSK HLA-DRB1 0 900 57 903 1 1
CTSK ZFP36 0 0 0 194 1 1
CTSK TNFSF10 0 0 167 167 1 2
CTSK MAP2K3 0 0 95 157 1 1
CTSK PMM2 0 0 0 158 1 1
CTSK PLAT 0 0 128 213 1 1
CTSK CD74 0 900 328 931 1 1
CTSK SGSH 0 0 45 205 1 1
CTSK CASP1 0 0 218 269 1 2
CTSK MAFB 0 0 242 336 1 1
CTSK STMN3 0 0 49 196 1 1
CTSK BCL2L11 0 0 140 215 1 2
CTSK MAPK12 0 0 0 216 1 1
CTSK KL 0 0 161 161 1 2
CTSK SERPINA1 0 0 154 233 1 2
CTSK POLDIP3 0 0 0 169 1 1
CTSK CALB1 0 0 0 159 1 1
CTSK UBE2F 0 0 0 160 1 1
CTSK CABLES1 0 0 42 159 1 1
CTSK CSTA 0 0 249 286 1 1
CTSK CCR5 0 0 159 229 1 1
CTSK DCSTAMP 0 0 857 886 1 1
CTSK GRN 0 0 123 223 1 1
CTSK LAMP2 0 0 219 290 1 2
CTSK HIVEP3 0 0 112 220 1 1
CTSK LCK 0 0 102 276 1 1
CTSK ANGPT2 0 0 113 171 1 1
CTSK TCIRG1 0 0 561 606 1 1
CTSK MMP2 0 0 611 666 1 2
CTSK MAT2A 0 0 0 185 1 1
CTSK OSCAR 0 0 681 758 1 1
CTSK CALR 0 0 113 174 1 1
CTSK CD8A 0 0 216 225 1 1
CTSK ADAM8 0 0 210 227 1 1
CTSK GUCY1A3 0 0 61 156 1 1
CTSK CXCL12 0 0 406 464 1 2
CTSK TPM1 0 0 73 207 1 1
CTSK TLR5 0 0 127 198 1 1
CTSK UBE2L3 0 0 0 189 1 1
CTSK RHOA 0 0 210 233 1 2
CTSK CD248 0 0 0 152 1 1
CTSK ESR2 0 0 167 180 1 1
CTSK LTBP2 0 0 66 218 1 1
CTSK ALX4 0 0 70 183 1 1
CTSK CEBPA 0 0 181 201 1 1
CTSK SP7 0 0 653 748 1 1
CTSK HPGDS 0 0 112 215 1 1
CTSK BACE2 0 0 61 282 1 1
CTSK IL3 0 0 180 179 1 1
CTSK FOSL1 0 0 184 202 1 1
CTSK TFEB 0 0 580 592 1 2
CTSK PDIA2 0 0 0 211 1 1
CTSK PAX8 0 0 401 410 1 1
CTSK DPP7 0 0 125 166 1 1
CTSK GLI3 0 0 75 152 1 1
CTSK ARID4B 311 0 0 311 1 1
CTSK FCGR2B 0 0 130 194 1 1
CTSK PAX5 0 0 66 199 1 1
CTSK B2M 0 0 204 244 1 1
CTSK ANGPT1 0 0 201 201 1 1
CTSK CD40 0 0 181 249 1 2
CTSK CTTN 0 0 155 156 1 1
CTSK INS 0 0 294 294 1 2
CTSK ACP1 0 0 0 165 1 1
CTSK ACTB 0 0 518 551 1 2
CTSK ADAMTS5 0 0 370 414 1 1
CTSK PLA2G4A 0 0 101 262 1 1
CTSK ERBB2IP 360 0 42 400 1 1
CTSK FAM20B 0 0 57 173 1 1
CTSK CALD1 0 0 240 239 1 1
CTSK ID1 0 0 122 174 1 1
CTSK MAPK13 0 0 48 276 1 1
CTSK PIR 0 0 0 211 1 1
CTSK CRISP2 0 0 0 224 1 1
CTSK WNT7B 0 0 150 173 1 1
CTSK ATP6V1H 0 0 155 300 1 1
CTSK HIF1A 0 0 273 288 1 2
CTSK EDN1 0 0 193 193 1 1
CTSK CYP27B1 0 0 149 161 1 1
CTSK TRAF5 0 0 276 281 1 1
CTSK IL1B 0 0 519 531 1 2
CTSK MATN4 0 0 76 168 1 1
CTSK LGR4 0 0 120 191 1 1
CTSK TNFRSF1A 0 0 204 285 1 1
CTSK RPS6 0 0 62 202 1 2
CTSK LEPRE1 0 0 108 189 1 1
CTSK PRKG1 0 0 66 150 1 1
CTSK LYZ 0 0 112 255 1 1
CTSK IL6 0 0 556 568 1 2
CTSK SYT7 0 0 487 487 1 1
CTSK UPB1 0 0 0 185 1 1
CTSK TRPV6 0 0 137 156 1 1
CTSK POTEF 0 0 180 236 1 1
CTSK BMP3 0 0 194 194 1 1
CTSK TRAF4 0 0 235 240 1 1
CTSK APEX2 0 0 0 231 1 1
CTSK FGF13 0 0 210 210 1 1
CTSK NOTCH1 0 0 234 327 1 2
CTSK ENSG00000278882 0 0 0 217 1 1
CTSK FIGNL1 0 0 0 181 1 1
CTSK PTGS1 0 0 324 378 1 1
CTSK PHEX 0 0 403 475 1 1
CTSK ANXA5 0 0 184 221 1 2
CTSK LGALS9 0 0 74 164 1 1
CTSK TAGLN 0 0 107 163 1 1
CTSK PCSK6 0 0 70 172 1 1
CTSK IFNG 0 0 210 237 1 2
CTSK BIRC2 0 600 0 600 1 1
CTSK PLCG2 0 0 324 345 1 1
CTSK TGFB3 0 0 210 261 1 1
CTSK CCL5 0 0 207 207 1 2
CTSK TWSG1 0 0 108 220 1 1
CTSK SIRPB1 0 0 240 239 1 1
CTSK PRCP 0 0 91 409 1 1
CTSK PSMA1 0 0 112 303 1 1
CTSK CD14 0 0 46 177 1 1
CTSK APOA1 0 0 81 235 1 1
CTSK SMAD2 0 0 242 241 1 2
CTSK CCDC50 0 0 51 185 1 1
CTSK EMR1 0 0 103 183 1 1
CTSK TLR4 0 0 323 359 1 2
CTSK C1R 0 0 85 194 1 1
CTSK SMOC2 0 0 0 155 1 1
CTSK BCL2L1 0 600 134 641 1 2
CTSK ANAPC5 0 0 96 175 1 1
CTSK EMCN 0 0 194 258 1 1
CTSK KITLG 0 0 244 243 1 1
CTSK CALCR 0 0 840 870 1 1
CTSK YJEFN3 0 0 0 165 1 1
CTSK MMP17 0 0 0 313 1 1
CTSK NAPSA 0 0 52 277 1 1
CTSK AP4S1 0 0 57 202 1 1
CTSK SPTBN2 0 0 0 270 1 1
CTSK TRAF2 0 0 226 231 1 2
CTSK TAB1 0 0 123 159 1 1
CTSK NOG 0 0 208 208 1 1
CTSK MX1 0 0 150 188 1 1
CTSK APOA1BP 0 0 0 165 1 1
CTSK GLDC 0 0 0 154 1 1
CTSK TAB2 0 0 180 179 1 2
CTSK HLA-DRB5 0 900 0 902 1 1
CTSK IGF1R 0 0 142 177 1 2
CTSK COL11A1 0 0 161 211 1 1
CTSK CPQ 0 0 96 150 1 1
CTSK TREM1 0 0 81 157 1 1
CTSK CORO6 0 0 0 165 1 1
CTSK APEX1 0 0 0 231 1 1
CTSK IL1R1 0 0 181 221 1 1
CTSK MYC 0 0 202 202 1 2
CTSK IL18 0 0 251 269 1 2
CTSK CD80 0 0 141 162 1 2
CTSK FURIN 0 0 123 219 1 1
CTSK UBBP4 0 0 0 163 1 1
CTSK OSM 0 0 219 219 1 1
CTSK TLR1 0 0 97 164 1 1
CTSK NHLRC2 0 0 74 226 1 1
CTSK PRSS3P2 0 0 142 180 1 1
CTSK ENSG00000272772 0 0 0 189 1 1
CTSK CTSV 645 0 528 664 1 1
CTSK ZNF423 0 0 211 260 1 1
CTSK CHI3L1 0 0 161 175 1 1
CTSK UBD 0 0 73 190 1 1
CTSK HDAC3 0 0 291 290 1 2
CTSK SMAD4 0 0 166 165 1 2
CTSK S1PR2 0 0 98 154 1 1
CTSK KDELR1 0 0 0 157 1 1
CTSK LCP2 0 0 104 270 1 1
CTSK LAMB2 0 0 0 154 1 1
CTSK CSF3 0 0 260 260 1 1
CTSK LMNA 0 0 108 178 1 2
CTSK HLA-DQB2 0 900 54 903 1 1
CTSK GZMH 0 0 0 258 1 1
CTSK CST2 0 0 193 268 1 1
CTSK PLOD1 0 0 91 151 1 1
CTSK TRAF1 0 0 218 243 1 1
CTSK PSTPIP1 0 0 92 167 1 1
CTSK MYD88 0 0 218 261 1 2
CTSK URM1 0 0 0 156 1 1
CTSK METAP2 0 0 49 161 1 1
CTSK COL9A3 0 0 150 203 1 1
CTSK FBLN2 0 0 75 251 1 1
CTSK PCOLCE 0 0 162 274 1 1
CTSK S100A1 0 0 112 189 1 1
CTSK HMBS 0 0 140 238 1 1
CTSK COL5A2 0 0 260 381 1 1
CTSK STAT3 0 0 282 297 1 2
CTSK DKK2 0 0 140 169 1 1
CTSK HTRA1 0 0 85 196 1 1
CTSK ATP6V0D1 0 0 125 218 1 1
CTSK SLC9B2 0 0 321 338 1 1
CTSK MTAP 0 0 67 181 1 1
CTSK TXNDC8 0 0 0 194 1 1
CTSK GATA3 0 0 95 152 1 1
CTSK RBP2 0 0 43 233 1 1
CTSK LY86 0 0 91 165 1 1
CTSK RPGR 0 0 0 177 1 1
CTSK WNT5B 0 0 123 158 1 1
CTSK COL2A1 0 0 324 367 1 2
CTSK HSCB 0 0 0 153 1 1
CTSK ZFAND4 0 0 0 169 1 1
CTSK HLA-DQB1 0 900 0 902 1 1
CTSK FNTA 0 0 61 173 1 1
CTSK WT1 0 0 113 168 1 1
CTSK PTRF 0 0 47 175 1 1
CTSK BMP4 0 0 323 476 1 1
CTSK LEP 0 0 266 310 1 1
CTSK SYK 0 0 323 335 1 2
CTSK NFKBIA 0 0 469 505 1 2
CTSK ANGPTL2 0 0 142 202 1 1
CTSK ONECUT2 0 0 484 483 1 1
CTSK TIMP3 0 0 264 301 1 1
CTSK MAPK14 0 0 218 337 1 2
CTSK LPXN 0 0 143 173 1 1
CTSK EIF4E1B 0 0 0 159 1 1
CTSK PTH1R 0 0 323 385 1 1
CTSK TXN2 0 0 0 156 1 1
CTSK MAPK7 0 0 89 164 1 1
CTSK NFIA 0 0 155 154 1 1
CTSK VEGFA 0 0 403 409 1 2
CTSK FCER1G 0 0 81 195 1 1
CTSK PI4KB 0 0 0 165 1 1
CTSK TRAF7 0 0 261 274 1 1
CTSK COL10A1 0 0 297 417 1 1
CTSK CDH11 0 0 323 436 1 1
CTSK ATG7 0 0 206 288 1 2
CTSK TGFBR2 0 0 155 369 1 1
CTSK ACTG1 0 0 183 206 1 1
CTSK RPL38 0 0 108 163 1 1
CTSK ITGB5 0 0 156 188 1 1
CTSK EFNB2 0 0 261 261 1 1
CTSK ATP6V0A1 0 0 91 280 1 1
CTSK RBPJ 0 0 157 176 1 1
CTSK CXCL2 0 0 161 161 1 1
CTSK COL1A1 0 0 517 638 1 2
CTSK PPARGC1B 0 0 147 170 1 1
CTSK CTSD 0 500 556 827 1 2
CTSK S1PR5 0 0 55 196 1 1
CTSK TMEM64 0 0 182 199 1 1
CTSK SMAD5 0 0 216 225 1 1
CTSK SFRP1 0 0 218 218 1 1
CTSK GNPTG 0 0 122 176 1 1
CTSK IKBKG 0 0 171 222 1 1
CTSK CASR 0 0 325 325 1 2
CTSK VTN 0 0 335 335 1 1
CTSK C1QC 0 0 76 186 1 1
CTSK ANO5 0 0 74 173 1 1
CTSK CTHRC1 0 0 218 284 1 1
CTSK CST4 0 0 390 447 1 1
CTSK TGFBR1 0 0 181 196 1 1
CTSK GALC 0 0 0 189 1 1
CTSK S100A4 0 0 226 297 1 1
CTSK CMA1 0 0 249 293 1 1
CTSK GLI1 0 0 115 172 1 2
CTSK ISG15 0 0 0 163 1 2
CTSK MCAM 0 0 161 161 1 1
CTSK CALCRL 0 0 122 257 1 1
CTSK ADAM17 0 0 174 254 1 1
CTSK SERPINB9 0 0 44 163 1 1
CTSK GUCY1B3 0 0 123 160 1 1
CTSK NFKBIB 0 0 60 172 1 1
CTSK WNT3A 0 0 262 275 1 2
CTSK LAPTM5 0 0 141 194 1 1
CTSK MAP2K6 0 0 134 193 1 1
CTSK ATG5 0 0 181 227 1 2
CTSK ITGB3 0 0 563 595 1 1
CTSK TLR8 0 0 328 344 1 1
CTSK SOX6 0 0 120 153 1 1
CTSK CST7 0 0 180 213 1 1
CTSK SPI1 0 0 503 568 1 1
CTSK NOX1 0 0 141 183 1 1
CTSK CTSB 0 300 701 535 1 2
CTSK MCL1 0 0 92 191 1 2
CTSK RBM10 0 0 223 223 1 1
CTSK DLK1 0 0 49 160 1 1
CTSK GNA11 0 0 457 457 1 1
CTSK BACE1 0 0 112 341 1 2
CTSK RGS1 0 0 46 193 1 1
CTSK ITGAM 0 0 370 383 1 1
CTSK HMGB1 0 0 125 212 1 2
CTSK ZFP36L1 0 0 0 174 1 1
CTSK IQCA1P1 0 0 0 181 1 1
CTSK PIK3CB 0 0 73 154 1 1
CTSK TLR2 0 0 275 297 1 2
CTSK CDKN2B 0 0 0 165 1 1
CTSK CST5 0 0 171 301 1 1
CTSK TRAF3 0 0 234 250 1 2
CTSK CCL7 0 0 170 213 1 1
CTSK TMX4 0 0 0 156 1 1
CTSK ENSG00000259040 0 0 0 178 1 1
CTSK ARL4C 0 0 539 552 1 1
CTSK SFRP2 0 0 189 240 1 1
CTSK SERPINB4 0 0 97 322 1 1
CTSK PDIA3 0 0 0 211 1 1
CTSK SLC40A1 0 0 134 183 1 1
CTSK RAB3D 0 0 171 225 1 1
CTSK AMACR 0 0 391 390 1 1
CTSK BGN 0 0 379 416 1 1
CTSK ANGPTL4 0 0 162 214 1 1
CTSK PITRM1 0 0 52 160 1 1
CTSK MSTN 0 0 137 224 1 1
CTSK PTPN11 0 0 116 228 1 1
CTSK MAT1A 0 0 0 185 1 1
CTSK FOS 0 0 708 726 1 2
CTSK TWIST1 0 0 202 235 1 1
CTSK MATK 0 0 103 180 1 1
CTSK ASPSCR1 0 0 469 469 1 1
CTSK SIGLEC15 0 0 157 175 1 1
CTSK TFE3 0 0 652 670 1 2
CTSK FTH1 0 0 66 180 1 1
CTSK SERPINB12 0 0 0 271 1 1
CTSK CAMK4 0 0 124 158 1 1
CTSK WNT2 0 0 113 344 1 1
CTSK ENSG00000250644 0 0 0 268 1 1
CTSK ATP6V1C1 0 0 211 238 1 1
CTSK COL5A3 0 0 167 214 1 1
CTSK KLF2 0 0 66 189 1 1
CTSK NME9 0 0 0 194 1 1
CTSK CHUK 0 0 232 276 1 1
CTSK PRCC 0 0 427 426 1 1
CTSK FABP4 0 0 181 307 1 1
CTSK EHBP1L1 0 0 0 175 1 1
CTSK BMPR1B 0 0 128 164 1 1
CTSK MGP 0 0 212 279 1 1
CTSK ITGAX 0 0 178 196 1 1
CTSK PABPC4L 0 0 181 259 1 1
CTSK AHSG 0 0 177 177 1 1
CTSK TRPV5 0 0 156 162 1 1
CTSK CSF1 0 0 681 729 1 1
CTSK PRDM1 0 0 145 187 1 1
CTSK AP1M2 0 0 64 230 1 1
CTSK IDS 0 0 46 160 1 1
CTSK ATP6V1B2 0 0 138 258 1 1
CTSK CXCL1 0 0 161 185 1 2
CTSK IL33 0 0 185 205 1 2
CTSK MMP14 0 0 403 487 1 1
CTSK SRPX2 0 0 90 165 1 1
CTSK PLEKHM1 0 0 322 448 1 1
CTSK OSR2 0 0 81 188 1 1
CTSK CSTB 0 0 359 389 1 1
CTSK ALOX5 0 0 152 153 1 1
CTSK NOTCH2 0 0 181 331 1 1
CTSK LUM 0 0 294 398 1 1
CTSK RAB7B 0 0 241 309 1 1
CTSK TGFB1 0 0 202 273 1 2
CTSK TM4SF19 0 0 92 159 1 1
CTSK MGAT5 0 0 56 169 1 1
CTSK VAMP7 0 0 46 167 1 2
CTSK ITGBL1 0 0 136 220 1 1
CTSK MRPS2 0 0 218 392 1 1
CTSK MMP10 0 0 261 391 1 1
CTSK PGA3 0 0 0 267 1 1
CTSK ENSG00000258674 0 0 0 165 1 1
CTSK ASPN 0 0 241 479 1 1
CTSK EGFL6 0 0 75 211 1 1
CTSK CORO2A 0 0 0 165 1 1
CTSK CLEC5A 0 0 180 179 1 1
CTSK PNP 0 0 58 218 1 1
CTSK AMT 0 0 0 545 1 1
CTSK FOXP3 0 0 166 180 1 2
CTSK RARRES2 0 0 172 171 1 1
CTSK KDR 0 0 173 204 1 2
CTSK DMP1 0 0 233 328 1 1
CTSK RAC2 0 0 145 217 1 1
CTSK TPSAB1 0 0 89 162 1 1
CTSK DDX39B 0 0 0 170 1 1
CTSK TXNDC9 0 0 0 156 1 1
CTSK CD93 0 0 150 186 1 1
CTSK TLR3 0 0 171 273 1 2
CTSK CORO1A 0 0 61 182 1 1
CTSK GTPBP3 0 0 0 263 1 1
CTSK JDP2 0 0 606 614 1 1
CTSK PLOD3 0 0 147 249 1 1
CTSK SERPINB3 270 0 170 447 1 1
CTSK SERPINB7 0 0 0 271 1 1
CTSK ALYREF 0 0 0 169 1 1
CTSK APOE 0 0 224 255 1 2
CTSK TRPV2 0 0 60 163 1 1
CTSK CBFB 0 650 108 674 1 1
CTSK BGLAP 0 0 735 746 1 1
CTSK CCT3 0 0 112 223 1 1
CTSK TNFSF11 0 0 900 911 1 2
CTSK CDC42 0 0 180 221 1 2
CTSK TMEM204 0 0 0 179 1 1
CTSK DKK1 0 0 509 513 1 1
CTSK IRF8 0 0 370 392 1 1
CTSK PDGFRL 0 0 52 174 1 1
CTSK FBN1 0 0 231 352 1 1
CTSK CRTAP 0 0 157 259 1 1
CTSK TPM3 0 0 76 209 1 1
CTSK TGFBI 0 0 124 253 1 1
CTSK KLK4 0 0 188 188 1 1
CTSK NID2 0 0 117 167 1 1
CTSK NGF 0 0 150 187 1 2
CTSK CD34 0 0 209 274 1 2
CTSK CTSO 0 0 134 346 1 1
CTSK BCL6 0 0 212 300 1 1
CTSK EFEMP1 0 0 55 187 1 1
CTSK CTRC 0 0 93 155 1 1
CTSK GJA1 0 0 234 234 1 1
CTSK ITPKC 0 0 0 161 1 1
CTSK CST6 0 0 51 172 1 1
CTSK ISLR 0 0 90 226 1 1
CTSK ENSG00000279392 0 0 0 189 1 1
CTSK TGIF2 0 0 112 216 1 1
CTSK NLRC4 0 0 306 319 1 2
CTSK COL4A2 0 0 151 216 1 1
CTSK LCN6 0 0 154 168 1 1
CTSK ZNF836 0 0 141 194 1 1
CTSK PCOLCE2 0 0 180 204 1 1
CTSK NOX4 0 0 123 210 1 2
CTSK CST3 0 0 507 584 1 1
CTSK CSF2 0 0 289 288 1 1
CTSK FBN2 0 0 125 252 1 1
CTSK CA9 0 0 342 342 1 1
CTSK MBTPS1 0 0 0 160 1 1
CTSK WDTC1 0 0 0 152 1 1
CTSK VCAM1 0 0 262 305 1 1
CTSK MEPE 0 0 378 378 1 1
CTSK F13A1 0 0 66 204 1 1
CTSK IFI30 0 0 144 166 1 1
CTSK COL8A2 0 0 112 238 1 1
CTSK MMP7 0 300 335 579 1 1
CTSK HRSP12 0 0 0 271 1 1
CTSK BAG4 0 0 83 176 1 1
CTSK VCL 0 0 218 239 1 1
CTSK RPLP0 0 0 454 482 1 1
CTSK SEMA4D 0 0 181 195 1 1
CTSK TIRAP 0 0 54 202 1 1
CTSK COL8A1 0 0 166 208 1 1
CTSK TSHR 0 0 118 180 1 1
CTSK LUC7L3 0 0 225 224 1 1
CTSK IL7 0 0 193 193 1 1
CTSK ADAMTS4 0 0 364 392 1 1
CTSK CD44 0 0 322 356 1 2
CTSK EPHB4 0 0 274 317 1 1
CTSK BTK 0 0 193 208 1 1
CTSK MAPK1 0 0 147 218 1 2
CTSK ITGA3 0 0 150 177 1 2
CTSK IGF1 0 0 393 420 1 2
CTSK CSF1R 0 0 562 645 1 1
CTSK TNMD 0 0 135 190 1 1
CTSK MYL4 0 0 47 151 1 1
CTSK AXIN2 0 0 125 177 1 1
CTSK VWF 0 0 143 244 1 1
CTSK TNFAIP6 0 0 117 182 1 1
CTSK IFNAR1 0 0 54 202 1 1
CTSK IQGAP2 0 0 0 155 1 1
CTSK SFRP4 0 0 218 365 1 1
CTSK FGF2 0 0 263 279 1 2
CTSK THNSL2 0 0 147 211 1 1
CTSK RELB 0 0 194 228 1 2
CTSK TXNDC11 0 0 0 211 1 1
CTSK ACTN1 0 0 120 214 1 1
CTSK TMX3 0 0 0 166 1 1
CTSK FAU 0 0 0 163 1 2
CTSK ANXA2 0 0 206 241 1 1
CTSK IRAK2 0 0 55 168 1 1
CTSK ACTA2 0 0 90 187 1 1
CTSK NOS3 0 0 122 175 1 2
CTSK SEMA3A 0 0 156 155 1 1
CTSK JUND 0 0 324 323 1 1
CTSK LOXL1 0 0 134 178 1 1
CTSK GPR143 0 0 398 406 1 1
CTSK FARSB 0 0 0 158 1 1
CTSK FSHR 0 0 85 248 1 1
CTSK CCND1 0 0 170 169 1 2
CTSK EIF4E 0 0 0 159 1 2
CTSK LECT2 0 0 60 546 1 1
CTSK KRT20 0 0 61 225 1 1
CTSK ENSG00000264813 0 0 252 262 1 1
CTSK LRP6 0 0 234 243 1 1
CTSK BMP5 0 0 134 164 1 1
CTSK S100A10 0 0 74 216 1 1
CTSK TXN 0 0 49 200 1 1
CTSK LCP1 0 0 62 195 1 1
CTSK RUNX1 0 650 0 671 1 2
CTSK COL6A3 0 0 181 357 1 1
CTSK PECAM1 0 0 254 254 1 1
CTSK IKZF5 0 0 122 176 1 1
CTSK UBB 0 0 0 163 1 1
CTSK PTK2B 0 0 281 298 1 1
CTSK XPR1 0 0 92 199 1 1
CTSK KLF9 0 0 62 180 1 1
CTSK PSMA7 0 0 144 197 1 1
CTSK CHIT1 0 0 194 208 1 1
CTSK GNB2L1 0 0 0 153 1 1
CTSK LDLR 0 0 160 161 1 2
CTSK COL7A1 0 0 149 179 1 1
CTSK ALPL 0 0 419 456 1 1
CTSK SMAD3 0 0 183 183 1 2
CTSK SPARC 213 0 518 663 1 2
CTSK PLS3 0 0 67 159 1 1
CTSK ANXA8 0 0 113 152 1 1
CTSK BIRC3 0 600 62 608 1 1
CTSK SERPINF1 0 0 177 272 1 1
CTSK ROCK1 0 0 67 158 1 2
CTSK HNF1B 0 0 103 156 1 1
CTSK NUMB 0 0 90 181 1 1
CTSK PDGFRB 0 0 113 250 1 2
CTSK SIRPA 0 0 187 210 1 1
CTSK DPT 0 0 47 179 1 1
CTSK IL4 0 0 321 321 1 1
CTSK DUX4L3 0 0 193 207 1 1
CTSK AP1M1 0 0 54 222 1 1
CTSK PVALB 0 0 69 183 1 1
CTSK ANXA3 0 0 66 196 1 1
CTSK MME 0 0 324 386 1 1
CTSK THBS4 0 0 142 160 1 1
CTSK PMP2 0 0 0 152 1 1
CTSK TYROBP 0 0 391 436 1 1
CTSK ARPC1B 0 0 0 459 1 1
CTSK IL16 0 0 75 204 1 1
CTSK TXNDC16 0 0 0 178 1 1
CTSK CCL2 0 0 369 414 1 2
CTSK ALB 0 0 342 376 1 2
CTSK CD68 0 0 466 524 1 2
CTSK CPXM2 0 0 0 160 1 1
CTSK FNDC1 0 0 0 158 1 1
CTSK SRGN 0 0 96 192 1 1
CTSK PSMB2 0 0 72 271 1 1
CTSK ROCK2 0 0 77 180 1 1
CTSK WNT1 0 0 213 213 1 2
CTSK MAF 0 0 134 153 1 1
CTSK PDGFRA 0 0 95 191 1 1
CTSK CDH1 0 0 260 272 1 2
CTSK PTGFRN 0 0 46 150 1 1
CTSK WNT16 0 0 241 252 1 1
CTSK CALCA 0 0 505 505 1 1
CTSK FGF18 0 0 149 171 1 1
CTSK ATP6V0D2 0 0 737 812 1 1
CTSK ITGA7 0 0 134 220 1 1
CTSK PTK2 0 0 166 190 1 2
CTSK FRZB 0 0 188 239 1 1
CTSK BMP1 0 0 211 247 1 1
CTSK MAPK8 0 0 288 288 1 2
CTSK COL4A1 0 0 195 218 1 1
CTSK CCR1 0 0 206 257 1 1
CTSK MMP16 0 0 161 335 1 1
CTSK VR1 0 0 139 170 1 1
CTSK MAPRE3 0 0 0 240 1 1
CTSK EFEMP2 0 0 55 222 1 1
CTSK TPM2 0 0 53 213 1 1
CTSK CCR2 0 0 210 253 1 2
CTSK DNPEP 0 0 0 194 1 1
CTSK PDCD4 0 0 112 154 1 2
CTSK HSP90B1 0 0 53 175 1 1
CTSK TEK 0 0 138 189 1 1
CTSK CXCL9 0 0 140 200 1 1
CTSK FIGN 0 0 0 181 1 1
CTSK HSPA4 0 0 108 196 1 1
CTSK CTSH 0 0 509 164 1 1
CTSK PLAUR 0 0 231 253 1 1
CTSK CLTC 0 0 150 182 1 1
CTSK DICER1 0 0 112 163 1 1
CTSK BMP2 0 0 518 779 1 1
CTSK CYP27A1 0 0 288 324 1 1
CTSK EGF 0 0 232 233 1 2
CTSK PRTN3 0 0 164 163 1 1
CTSK FBLN5 0 0 74 307 1 1
CTSK PLAU 0 0 261 282 1 1
CTSK SLC6A8 0 0 0 162 1 1
CTSK TRAF6 0 0 631 687 1 2
CTSK ACP2 0 0 122 154 1 1
CTSK VCAN 0 0 254 270 1 1
CTSK COL18A1 0 900 142 913 1 1
CTSK ZNF528 0 0 101 157 1 1
CTSK PAPL 0 0 0 225 1 1
CTSK COL16A1 0 0 166 281 1 1
CTSK JUN 0 0 468 477 1 2
CTSK CDH17 0 0 160 174 1 1
CTSK SERPINB2 0 0 125 335 1 1
CTSK TPP1 0 0 124 152 1 1
CTSK DUX4L2 0 0 244 257 1 1
CTSK WDR31 0 0 0 153 1 1
CTSK ENSG00000173366 0 0 306 307 1 1
CTSK CYP19A1 0 0 151 172 1 2
CTSK S1PR4 0 0 50 211 1 1
CTSK CORO2B 0 0 0 165 1 1
CTSK PARP14 0 0 140 193 1 1
CTSK COMP 0 0 276 352 1 1
CTSK SULF1 0 0 87 233 1 1
CTSK TPP2 0 0 0 213 1 1
CTSK FDPS 0 0 267 299 1 1
CTSK GRB2 0 0 122 296 1 1
CTSK CTSF 0 0 503 247 1 1
CTSK FST 0 0 164 194 1 1
CTSK JAG1 0 0 220 301 1 1
CTSK ARSA 0 0 416 429 1 2
CTSK COL3A1 0 0 309 522 1 1
CTSK TREM2 0 0 325 364 1 1
CTSK TBXAS1 0 0 148 186 1 1
CTSK RAB27A 0 0 143 201 1 1
CTSK SMAD1 0 0 90 178 1 2
CTSK CHST3 0 0 143 330 1 1
CTSK BMP6 0 0 314 313 1 1
CTSK TIMP1 0 0 400 431 1 1
CTSK CCL18 0 0 155 226 1 1
CTSK MYL1 0 0 53 156 1 1
CTSK FABP5 0 0 0 154 1 1
CTSK BID 0 600 66 610 1 2
CTSK GSN 0 0 137 192 1 1
CTSK ERP44 0 0 0 168 1 1
CTSK SPP1 0 0 689 696 1 2
CTSK ICAM1 0 0 261 279 1 2
CTSK SOX9 0 0 323 323 1 1
CTSK SOST 0 0 710 716 1 1
CTSK PRG4 0 0 162 175 1 1
CTSK OMD 0 0 207 249 1 1
CTSK PTPRC 0 0 251 269 1 1
CTSK ATP6V0B 0 0 47 167 1 1
CTSK ITGAV 0 0 507 517 1 1
CTSK IGFBP2 0 0 160 159 1 1
CTSK COL14A1 0 0 245 285 1 1
CTSK CRP 0 0 252 252 1 2
CTSK SYT1 0 0 307 307 1 1
CTSK PRRX1 0 0 162 286 1 1
CTSK LASP1 0 0 53 167 1 1
CTSK HSP90AA1 0 0 137 187 1 2
CTSK BNIP3 0 0 81 193 1 2
CTSK SPINT4 0 0 100 152 1 1
CTSK MMP9 0 300 753 857 1 2
CTSK TKTL1 0 0 0 213 1 1
CTSK MAPK3 0 0 289 348 1 2
CTSK THY1 0 0 134 157 1 1
CTSK EPRS 0 0 82 164 1 1
CTSK RPS2 0 0 122 161 1 1
CTSK SNX10 0 0 324 427 1 2
CTSK MTSS1 0 0 103 192 1 1
CTSK PMM1 0 0 66 250 1 1
CTSK WNT2B 0 0 124 218 1 1
CTSK DDR2 0 0 90 155 1 1
CTSK C3AR1 0 0 125 184 1 1
CTSK IGSF23 0 0 150 504 1 1
CTSK CTNNB1 0 0 414 429 1 2
CTSK OSTM1 0 0 518 547 1 1
CTSK ATP6V1B1 0 0 0 207 1 1
CTSK HRAS 0 0 112 168 1 2
CTSK EGR1 0 0 96 183 1 2
CTSK DCAF6 0 0 0 152 1 1
CTSK S1PR3 0 0 95 159 1 1
CTSK DLK2 0 0 0 160 1 1
CTSK TRPV1 0 0 139 170 1 2
CTSK DLX4 0 0 0 201 1 1
CTSK CXCL8 0 0 367 367 1 2
CTSK FOLR2 0 0 72 156 1 1
CTSK CTSL 603 500 733 811 1 2
CTSK PAX2 0 0 95 173 1 1
CTSK POSTN 0 0 372 513 1 1
CTSK VAV3 0 0 283 282 1 1
CTSK STAT1 0 0 180 262 1 2
CTSK SCPEP1 0 0 55 259 1 1
CTSK GZMB 0 0 95 300 1 1
CTSK CILP 0 0 73 232 1 1
CTSK OCLN 0 0 66 160 1 1
CTSK HFE2 0 0 0 302 1 1
CTSK B4GALNT3 0 0 63 184 1 1
CTSK ACAN 0 0 464 476 1 1
CTSK ETS2 0 0 70 228 1 1
CTSK CTRL 0 0 156 242 1 2
CTSK IGFBP7 0 0 94 194 1 1
CTSK MTOR 0 0 243 264 1 2
CTSK UBL4B 0 0 0 163 1 1
CTSK PSMB4 0 0 0 164 1 1
CTSK TIMP4 0 0 213 230 1 1
CTSK CD163 0 0 171 267 1 1
CTSK ZNF12 0 0 70 233 1 1
CTSK CYR61 0 0 100 194 1 1
CTSK CXCR4 0 0 325 333 1 2
CTSK MMP1 0 0 469 506 1 1
CTSK SH3BP2 0 0 278 323 1 1
CTSK DIAPH1 0 0 386 386 1 1
CTSK SERPINI2 0 0 53 164 1 1
CTSK SERPINI1 0 0 0 151 1 1
CTSK EPHX4 0 0 66 228 1 1
CTSK GRID2IP 0 0 0 196 1 1
CTSK CA2 0 0 683 705 1 1
CTSK IQGAP1 0 0 45 159 1 1
CTSK CRISP3 0 0 0 224 1 1
CTSK HSD11B1 0 0 72 189 1 1
CTSK HLA-DQA2 0 900 48 900 1 1
CTSK G0S2 0 0 45 167 1 1
CTSK CREB1 0 0 204 214 1 2
CTSK CCL13 0 0 74 162 1 1
CTSK ESRRA 0 0 136 182 1 1
CTSK SDHB 0 0 150 157 1 1
CTSK HLA-DPB1 0 900 57 905 1 1
CTSK MAP2K7 0 0 150 169 1 1
CTSK FGFR2 0 0 123 176 1 1
CTSK ENO1 0 0 113 161 1 1
CTSK GREM1 0 0 167 198 1 1
CTSK GAPDH 0 0 556 577 1 2
CTSK NFKB1 0 0 125 221 1 2
CTSK RELA 0 0 246 245 1 2
CTSK MMP20 0 300 202 518 1 1
CTSK ITGA4 0 0 107 152 1 1
CTSK GAB2 0 0 241 240 1 1
CTSK ACP5 0 0 911 919 1 1
CTSK RICTOR 0 0 75 241 1 2
CTSK P4HB 0 0 55 222 1 2
CTSK ATP6V1G1 0 0 150 240 1 1
CTSK IBSP 0 0 563 575 1 1
CTSK RGS10 0 0 124 210 1 1
CTSK JMJD7 0 0 134 153 1 1
CTSK ADAM10 0 0 154 236 1 1
CTSK MATN2 0 0 81 173 1 1
CTSK IL15 0 0 145 173 1 1
CTSK LGMN 0 500 335 669 1 1
CTSK PGA5 0 0 0 267 1 1
CTSK WNT5A 0 0 247 282 1 2
CTSK OASL 0 0 0 163 1 1
CTSK AREG 0 0 124 178 1 1
CTSK AQP1 0 0 72 178 1 1
CTSK CHN2 0 0 156 155 1 1
CTSK MYL9 0 0 45 158 1 1
CTSK OGN 0 0 193 269 1 1
CTSK SCUBE3 0 0 93 187 1 1
CTSK GLT8D2 0 0 210 295 1 1
CTSK DDX39A 0 0 0 170 1 1
CTSK LRP5 0 0 459 482 1 1
CTSK TFEC 0 0 610 637 1 1
CTSK CTSE 0 0 310 472 1 1
CTSK MAP3K7 0 0 170 185 1 2
CTSK WNT4 0 0 144 160 1 1
CTSK CTSA 0 0 292 437 1 1
CTSK TNFRSF11B 0 0 759 787 1 1
CTSK LAMA4 0 0 117 188 1 1
CTSK PSTPIP2 0 0 103 270 1 1
CTSK ADAMTS1 0 0 200 238 1 1
CTSK FGFR3 72 0 157 225 1 1
CTSK LAMP1 0 0 211 269 1 2
CTSK EGFR 0 0 161 161 1 2
CTSK ECM1 0 0 445 486 1 1
CTSK SLC26A4 0 0 142 152 1 1
CTSK LCN2 0 0 142 160 1 1
CTSK TP53 0 0 211 211 1 2
CTSK DCN 0 0 325 508 1 2
CTSK CTNNA1 0 0 0 159 1 1
CTSK ZCCHC8 0 0 0 234 1 1
CTSK ARSB 0 0 145 266 1 2
CTSK GPR85 0 0 166 171 1 1
CTSK CPVL 0 0 0 237 1 1
CTSK RHBDL3 0 0 0 174 1 1
CTSK HBEGF 0 0 125 179 1 1
CTSK PCSK5 0 0 62 165 1 1
CTSK ITGA5 0 0 184 243 1 1
CTSK SFPQ 0 0 232 231 1 1
CTSK MMP15 0 0 113 361 1 1
CTSK SERPINH1 0 0 245 282 1 1
CTSK CLU 0 0 625 625 1 2
CTSK CTSW 0 0 391 328 1 1
CTSK CHST11 0 0 95 151 1 1
CTSK HSPA12B 0 0 0 163 1 1
CTSK CDH2 0 0 193 206 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0005518 Molecular Function collagen binding enables IDA
GO:0008656 Molecular Function cysteine-type endopeptidase activator activity involved in apoptotic process enables IBA
GO:0004197 Molecular Function cysteine-type endopeptidase activity enables IBA
GO:0004197 Molecular Function cysteine-type endopeptidase activity enables IDA
GO:0008234 Molecular Function cysteine-type peptidase activity enables IDA
GO:0001968 Molecular Function fibronectin binding enables IPI
GO:0005515 Molecular Function protein binding enables IPI
GO:0043394 Molecular Function proteoglycan binding enables IPI
GO:0004252 Molecular Function serine-type endopeptidase activity enables TAS
GO:0006915 Biological Process apoptotic process involved_in IEA
GO:0000422 Biological Process autophagy of mitochondrion involved_in HMP
GO:0045453 Biological Process bone resorption involved_in IEA
GO:0071560 Biological Process cellular response to transforming growth factor beta stimulus involved_in IEA
GO:0071356 Biological Process cellular response to tumor necrosis factor involved_in IEA
GO:0034224 Biological Process cellular response to zinc ion starvation involved_in IEA
GO:0030574 Biological Process collagen catabolic process acts_upstream_of_or_within IDA
GO:0030574 Biological Process collagen catabolic process involved_in IDA
GO:0022617 Biological Process extracellular matrix disassembly involved_in TAS
GO:0006955 Biological Process immune response involved_in IBA
GO:0001957 Biological Process intramembranous ossification involved_in IEA
GO:1903131 Biological Process mononuclear cell differentiation involved_in IEA
GO:0061037 Biological Process negative regulation of cartilage development involved_in IEA
GO:2001235 Biological Process positive regulation of apoptotic signaling pathway involved_in IBA
GO:0010952 Biological Process positive regulation of peptidase activity involved_in IBA
GO:0006508 Biological Process proteolysis involved_in TAS
GO:0051603 Biological Process proteolysis involved in protein catabolic process involved_in IBA
GO:0051603 Biological Process proteolysis involved in protein catabolic process involved_in IDA
GO:0045471 Biological Process response to ethanol involved_in IEA
GO:0032868 Biological Process response to insulin involved_in IEA
GO:0014070 Biological Process response to organic cyclic compound involved_in IEA
GO:0006590 Biological Process thyroid hormone generation involved_in IDA
GO:0016324 Cellular Component apical plasma membrane located_in IEA
GO:0036021 Cellular Component endolysosome lumen located_in TAS
GO:0009897 Cellular Component external side of plasma membrane located_in IEA
GO:0005576 Cellular Component extracellular region located_in TAS
GO:0005615 Cellular Component extracellular space is_active_in IBA
GO:0005615 Cellular Component extracellular space located_in IDA
GO:0043231 Cellular Component intracellular membrane-bounded organelle located_in IDA
GO:0043202 Cellular Component lysosomal lumen located_in TAS
GO:0005764 Cellular Component lysosome is_active_in IBA
GO:0005764 Cellular Component lysosome located_in IDA
GO:0005654 Cellular Component nucleoplasm located_in IDA
Pathways
Name DB ID
Adaptive Immune System Reactome R-HSA-1280218
Collagen degradation Reactome R-HSA-1442490
Degradation of the extracellular matrix Reactome R-HSA-1474228
Extracellular matrix organization Reactome R-HSA-1474244
Activation of Matrix Metalloproteinases Reactome R-HSA-1592389
Trafficking and processing of endosomal TLR Reactome R-HSA-1679131
Innate Immune System Reactome R-HSA-168249
Immune System Reactome R-HSA-168256
Toll-like Receptor Cascades Reactome R-HSA-168898
Generic Transcription Pathway Reactome R-HSA-212436
MHC class II antigen presentation Reactome R-HSA-2132295
RNA Polymerase II Transcription Reactome R-HSA-73857
Gene expression (Transcription) Reactome R-HSA-74160
Transcriptional regulation by RUNX1 Reactome R-HSA-8878171
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes Reactome R-HSA-8939242
Osteoclast signaling (WP12) WikiPathways WP12_r116896
Clock-controlled autophagy in bone metabolism (WP5205) WikiPathways WP5205_r122560
Overlap between signal transduction pathways contributing to LMNA laminopathies (WP4879) WikiPathways WP4879_r123415
Type 2 papillary renal cell carcinoma (WP4241) WikiPathways WP4241_r123413
RANKL/RANK signaling pathway (WP2018) WikiPathways WP2018_r120672
Transcripts
Accession Version MolecularType Name NCBI Comments
NM_000396 4 mRNA None NC_000001 Reference