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NQO1

NAD(P)H quinone dehydrogenase 1
General Information
Name NAD(P)H quinone dehydrogenase 1
Alias
  • NAD(P)H dehydrogenase [quinone] 1
  • DT-diaphorase
  • NAD(P)H dehydrogenase, quinone 1
  • NAD(P)H-quinone oxidoreductase
  • NAD(P)H:Quinone acceptor oxidoreductase type 1
  • NAD(P)H:menadione oxidoreductase 1
  • NAD(P)H:quinone oxidoreductase 1
  • NAD(P)H:quinone oxireductase
  • azoreductase
  • diaphorase (NADH/NADPH) (cytochrome b-5 reductase)
  • diaphorase-4
  • dioxin-inducible 1
  • menadione reductase
  • phylloquinone reductase
  • quinone reductase 1
Gene_family
organism Homo sapiens
entrez_id 1728
location 16q22.1
transcript_count 4
exon_count 6
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
    Stringdb NAD(P)H dehydrogenase [quinone] 1; The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis; Belongs to the NAD(P)H dehydrogenase (quinone) family
    nextProt Flavin-containing quinone reductase that catalyzes two-electron reduction of quinones to hydroquinones using either NADH or NADPH as electron donors. In a ping-pong kinetic mechanism, the electrons are sequentially transferred from NAD(P)H to flavin cofactor and then from reduced flavin to the quinone, bypassing the formation of semiquinone and reactive oxygen species (PubMed:8999809, PubMed:9271353) (By similarity). Regulates cellular redox state primarily through quinone detoxification. Reduces components of plasma membrane redox system such as coenzyme Q and vitamin quinones, producing antioxidant hydroquinone forms. In the process may function as superoxide scavenger to prevent hydroquinone oxidation and facilitate excretion (PubMed:8999809, PubMed:9271353, PubMed:15102952). Alternatively, can activate quinones and their derivatives by generating redox reactive hydroquinones with DNA cross-linking antitumor potential (PubMed:8999809). Acts as a gatekeeper of the core 20S proteasome known to degrade proteins with unstructured regions. Upon oxidative stress, interacts with tumor suppressors TP53 and TP73 in a NADH-dependent way and inhibits their ubiquitin-independent degradation by the 20S proteasome (PubMed:15687255, PubMed:28291250).
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
NQO1 BioGRID SNAI1 GeneID BioGRID Affinity Capture-Western
NQO1 BioGRID EZH2 GeneID BioGRID Affinity Capture-MS
NQO1 BioGRID RAF1 GeneID BioGRID Affinity Capture-MS
NQO1 BioGRID TRIM67 GeneID BioGRID Affinity Capture-MS
NQO1 BioGRID ZRANB1 GeneID BioGRID Affinity Capture-MS
NQO1 BioGRID BROX GeneID BioGRID Co-fractionation
NQO1 BioGRID CMBL GeneID BioGRID Co-fractionation
NQO1 BioGRID LYPLAL1 GeneID BioGRID Co-fractionation
NQO1 BioGRID NIT2 GeneID BioGRID Co-fractionation
NQO1 BioGRID TKFC GeneID BioGRID Co-fractionation
NQO1 BioGRID PTGR1 GeneID BioGRID Co-fractionation
NQO1 BioGRID PARK7 GeneID BioGRID Co-fractionation
NQO1 BioGRID PRDX6 GeneID BioGRID Co-fractionation
NQO1 BioGRID AKR1C3 GeneID BioGRID Co-fractionation
NQO1 BioGRID TST GeneID BioGRID Co-fractionation
NQO1 BioGRID TPI1 GeneID BioGRID Co-fractionation
NQO1 BioGRID PEBP1 GeneID BioGRID Co-fractionation
NQO1 BioGRID MB GeneID BioGRID Co-fractionation
NQO1 BioGRID GPI GeneID BioGRID Co-fractionation
NQO1 BioGRID GOT2 GeneID BioGRID Co-fractionation
NQO1 BioGRID CRYZ GeneID BioGRID Co-fractionation
NQO1 BioGRID CFL2 GeneID BioGRID Co-fractionation
NQO1 BioGRID ASS1 GeneID BioGRID Co-fractionation
NQO1 BioGRID ANXA11 GeneID BioGRID Co-fractionation
NQO1 BioGRID ADH5 GeneID BioGRID Co-fractionation
NQO1 BioGRID VCP GeneID BioGRID Affinity Capture-MS
NQO1 BioGRID SOX2 GeneID BioGRID Affinity Capture-MS
NQO1 BioGRID PIK3C2A GeneID BioGRID Affinity Capture-MS
NQO1 BioGRID INPPL1 GeneID BioGRID Affinity Capture-MS
NQO1 BioGRID MKRN1 GeneID BioGRID Affinity Capture-MS
NQO1 BioGRID TRIM26 GeneID BioGRID Affinity Capture-MS
NQO1 BioGRID TEK GeneID BioGRID Affinity Capture-MS
NQO1 BioGRID MID1 GeneID BioGRID Affinity Capture-MS
NQO1 BioGRID PRKN GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Co-localization
NQO1 BioGRID AKT1 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Co-localization
NQO1 BioGRID BRD4 GeneID BioGRID Affinity Capture-MS
NQO1 BioGRID CDC42 GeneID BioGRID Reconstituted Complex
NQO1 BioGRID PSMD2 GeneID BioGRID Affinity Capture-Western
NQO1 BioGRID SIRT6 GeneID BioGRID Affinity Capture-Western
NQO1 BioGRID GRB2 GeneID BioGRID Affinity Capture-MS
NQO1 BioGRID CAV1 GeneID BioGRID Affinity Capture-MS
NQO1 BioGRID SH2D3C GeneID BioGRID Affinity Capture-MS
NQO1 BioGRID GALT GeneID BioGRID Two-hybrid
NQO1 BioGRID AK4 GeneID BioGRID Co-fractionation
NQO1 BioGRID DCAF15 GeneID BioGRID Proximity Label-MS
NQO1 BioGRID TP73 GeneID BioGRID Co-crystal Structure
NQO1 BioGRID NQO1 GeneID BioGRID Co-crystal Structure; Co-purification; Reconstituted Complex
NQO1 BioGRID Psmb1 GeneID BioGRID Biochemical Activity; Reconstituted Complex
NQO1 BioGRID Psmb7 GeneID BioGRID Biochemical Activity; Reconstituted Complex
NQO1 BioGRID Psmb4 GeneID BioGRID Biochemical Activity; Reconstituted Complex
NQO1 BioGRID Psmb3 GeneID BioGRID Biochemical Activity; Reconstituted Complex
NQO1 BioGRID Psmb2 GeneID BioGRID Biochemical Activity; Reconstituted Complex
NQO1 BioGRID Psma7 GeneID BioGRID Biochemical Activity; Reconstituted Complex
NQO1 BioGRID Psma6 GeneID BioGRID Biochemical Activity; Reconstituted Complex
NQO1 BioGRID Psma5 GeneID BioGRID Biochemical Activity; Reconstituted Complex
NQO1 BioGRID Psma4 GeneID BioGRID Biochemical Activity; Reconstituted Complex
NQO1 BioGRID Psma3 GeneID BioGRID Biochemical Activity; Reconstituted Complex
NQO1 BioGRID Psma2 GeneID BioGRID Biochemical Activity; Reconstituted Complex
NQO1 BioGRID Psma1 GeneID BioGRID Biochemical Activity; Reconstituted Complex
NQO1 BioGRID Psmb6 GeneID BioGRID Biochemical Activity; Reconstituted Complex
NQO1 BioGRID Psmb5 GeneID BioGRID Biochemical Activity; Reconstituted Complex
NQO1 BioGRID TP53 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
NQO1 BioGRID AGR2 GeneID BioGRID Affinity Capture-MS
NQO1 BioGRID HIF1A GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
NQO1 BioGRID TNF GeneID BioGRID Affinity Capture-MS
NQO1 BioGRID STUB1 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
NQO1 BioGRID UBE2D1 GeneID BioGRID Biochemical Activity
NQO1 BioGRID TRIM25 GeneID BioGRID Affinity Capture-RNA
NQO1 BioGRID NDUFS7 GeneID BioGRID Affinity Capture-MS
NQO1 BioGRID DAZAP1 GeneID BioGRID Co-fractionation
NQO1 BioGRID FUBP3 GeneID BioGRID Co-fractionation
NQO1 BioGRID NME1 GeneID BioGRID Co-fractionation
NQO1 BioGRID GOT1 GeneID BioGRID Co-fractionation
NQO1 BioGRID ADK GeneID BioGRID Co-fractionation
NQO1 BioGRID NXF1 GeneID BioGRID Affinity Capture-RNA
NQO1 BioGRID MOV10 GeneID BioGRID Affinity Capture-RNA
NQO1 BioGRID FOS GeneID BioGRID Affinity Capture-Western; Co-fractionation; Co-localization
NQO1 BioGRID NFE2L2 GeneID BioGRID Affinity Capture-Western
NQO1 BioGRID PARP1 GeneID BioGRID Affinity Capture-Western
NQO1 BioGRID BAG3 GeneID BioGRID Affinity Capture-Luminescence; Affinity Capture-MS
NQO1 BioGRID ITGA4 GeneID BioGRID Affinity Capture-MS
NQO1 BioGRID FN1 GeneID BioGRID Affinity Capture-MS
NQO1 BioGRID RPS10P5 GeneID BioGRID Co-fractionation
NQO1 BioGRID POLDIP3 GeneID BioGRID Co-fractionation
NQO1 BioGRID YTHDF1 GeneID BioGRID Co-fractionation
NQO1 BioGRID RPS19 GeneID BioGRID Co-fractionation
NQO1 BioGRID LAMB1 GeneID BioGRID Co-fractionation
NQO1 BioGRID ING1 GeneID BioGRID Reconstituted Complex
NQO1 Protein DNAJB1 GeneID HPRD
NQO1 Protein TP53 GeneID HPRD
NQO1 Protein HSPA1A GeneID HPRD
NQO1 Protein NQO1 GeneID HPRD
NQO1 BioGRID HSPA4 GeneID BioGRID Affinity Capture-Western
StringDB
A B experiments database textmining combined score hadb nhadb
NQO1 CREB1 0 0 270 270 1 2
NQO1 CCL5 0 0 193 193 1 2
NQO1 AKR1B10 0 0 417 520 1 1
NQO1 AMER1 0 0 172 171 1 1
NQO1 GCSH 0 0 127 159 1 1
NQO1 IFNG 0 0 174 205 1 2
NQO1 NOX3 0 0 139 159 1 1
NQO1 CREBBP 0 0 156 171 1 1
NQO1 HSPA1L 0 0 83 277 1 1
NQO1 CYP17A1 0 0 187 187 1 1
NQO1 NFE2 0 0 631 631 1 1
NQO1 CALB2 0 0 415 414 1 1
NQO1 HAVCR1 0 0 181 181 1 1
NQO1 UGT2A3 0 0 96 452 1 1
NQO1 LONP1 0 0 66 166 1 1
NQO1 ESRRA 0 0 133 167 1 1
NQO1 SDHB 0 0 260 260 1 1
NQO1 PFKFB3 0 0 108 246 1 2
NQO1 HCAR2 0 0 184 183 1 1
NQO1 UGDH 0 0 335 382 1 1
NQO1 ETFA 0 0 0 159 1 1
NQO1 EPO 0 0 201 206 1 2
NQO1 GSTO2 0 0 181 181 1 1
NQO1 PRDX6 0 0 242 285 1 1
NQO1 PRDX5 0 0 263 263 1 1
NQO1 SIRT2 0 0 294 298 1 2
NQO1 RGS4 0 0 45 203 1 1
NQO1 ALDH3B2 0 0 61 175 1 1
NQO1 MGMT 0 0 212 271 1 2
NQO1 SULT2A1 0 0 244 243 1 1
NQO1 TAGLN 0 0 102 158 1 1
NQO1 FGF21 0 0 262 262 1 2
NQO1 CCNB1 0 0 215 253 1 1
NQO1 ANXA5 0 0 391 431 1 2
NQO1 UGT3A2 0 0 0 256 1 1
NQO1 TUBB4A 0 0 123 155 1 1
NQO1 BCL2L1 0 0 391 390 1 2
NQO1 RELA 0 0 231 230 1 2
NQO1 ALDOA 0 0 87 170 1 1
NQO1 PRODH 0 0 212 212 1 1
NQO1 DNMT3B 0 0 213 213 1 1
NQO1 SMOC2 0 0 0 208 1 1
NQO1 XPA 0 0 180 228 1 1
NQO1 NFKB1 0 0 172 171 1 2
NQO1 DNMT3A 0 0 233 232 1 2
NQO1 UHRF1 0 0 71 169 1 1
NQO1 DPEP2 0 0 0 249 1 1
NQO1 ME1 0 0 408 449 1 1
NQO1 GSTM3 0 0 519 571 1 1
NQO1 DPP3 0 0 270 270 1 1
NQO1 MAP2K7 0 0 235 235 1 1
NQO1 NOS2 0 0 286 286 1 2
NQO1 GABARAPL2 0 0 127 161 1 2
NQO1 HAMP 0 0 124 193 1 1
NQO1 GSTO1 0 0 330 335 1 1
NQO1 GAPDH 0 0 602 616 1 2
NQO1 CYP1A1 0 0 745 761 1 2
NQO1 TMBIM4 0 0 72 166 1 1
NQO1 AKR7A3 0 0 393 496 1 1
NQO1 CYP1A2 0 0 529 529 1 1
NQO1 TLR4 0 0 341 341 1 2
NQO1 CTSL 0 0 97 163 1 2
NQO1 KLK3 0 0 166 165 1 1
NQO1 MTPAP 0 0 81 241 1 1
NQO1 TTC31 0 0 0 194 1 1
NQO1 CCDC90B 0 0 82 223 1 1
NQO1 CXCL8 0 0 395 394 1 2
NQO1 NDRG1 0 0 62 163 1 1
NQO1 PIR 0 0 87 359 1 1
NQO1 IL1B 0 0 564 564 1 2
NQO1 CEP128 0 0 55 152 1 1
NQO1 PSMC2 0 0 108 163 1 1
NQO1 SLC22A8 0 0 134 157 1 1
NQO1 SIRT5 0 0 282 286 1 1
NQO1 MT1E 0 0 487 493 1 1
NQO1 HIF1A 283 0 594 697 1 2
NQO1 EDN1 0 0 171 171 1 1
NQO1 MT4 0 0 306 329 1 1
NQO1 CYP27B1 0 0 172 171 1 1
NQO1 CYP4F2 0 0 252 252 1 1
NQO1 BAG3 270 0 81 420 1 2
NQO1 AK4 115 0 0 212 1 1
NQO1 XPO1 0 0 125 277 1 1
NQO1 MSI1 0 0 0 190 1 1
NQO1 CYP4B1 0 0 206 217 1 1
NQO1 COQ9 0 0 151 160 1 1
NQO1 WIPF3 0 0 60 302 1 1
NQO1 PSAT1 0 0 155 212 1 1
NQO1 KCTD5 0 0 60 215 1 1
NQO1 CLEC18A 0 0 81 184 1 1
NQO1 EGR1 0 0 181 181 1 2
NQO1 SHMT2 0 0 75 174 1 1
NQO1 APP 0 0 232 231 1 2
NQO1 MFN2 0 0 150 171 1 2
NQO1 CDK2 0 0 220 256 1 2
NQO1 DPEP3 0 0 0 249 1 1
NQO1 HRAS 0 0 342 352 1 2
NQO1 AKR1C3 0 0 460 552 1 1
NQO1 MAP1LC3A 0 0 125 187 1 2
NQO1 CTNNB1 0 0 282 282 1 2
NQO1 SULT1B1 0 0 193 193 1 1
NQO1 CHD6 0 0 210 214 1 1
NQO1 POTEF 0 0 240 317 1 1
NQO1 RAD51 0 0 180 179 1 2
NQO1 PDCD5 0 0 66 192 1 1
NQO1 SULT1A2 0 0 235 235 1 1
NQO1 MTOR 0 0 282 282 1 2
NQO1 PTGS1 0 0 170 169 1 1
NQO1 SULT1A1 0 0 459 459 1 1
NQO1 MMP1 0 0 211 249 1 1
NQO1 NOTCH1 0 0 212 212 1 2
NQO1 SMOX 0 0 150 169 1 1
NQO1 HLA-G 0 0 292 292 1 1
NQO1 FMO1 0 0 247 316 1 1
NQO1 ABCB11 0 0 210 219 1 1
NQO1 OCLN 0 0 256 265 1 1
NQO1 CYP2F1 0 0 209 209 1 1
NQO1 SHMT1 0 0 134 191 1 1
NQO1 ALDH3B1 0 0 90 184 1 1
NQO1 CYP2C18 0 0 286 286 1 1
NQO1 RAD51C 0 0 307 307 1 1
NQO1 DNAJB4 0 0 81 260 1 1
NQO1 STAT1 0 0 166 171 1 2
NQO1 IL6 0 0 562 570 1 2
NQO1 CTRL 0 0 194 194 1 2
NQO1 VAT1 0 0 0 160 1 1
NQO1 EPHX2 0 0 140 252 1 1
NQO1 MPO 0 0 505 505 1 2
NQO1 PALB2 0 0 307 307 1 1
NQO1 UCP2 0 0 279 279 1 2
NQO1 MYD88 0 0 165 165 1 2
NQO1 CDK4 0 0 254 272 1 2
NQO1 EGFR 0 0 323 355 1 2
NQO1 NEDD8 0 0 117 167 1 2
NQO1 SLC2A1 0 0 228 280 1 2
NQO1 TALDO1 0 0 289 319 1 1
NQO1 AASS 0 0 141 280 1 1
NQO1 ERCC2 0 0 283 282 1 1
NQO1 GART 0 0 73 251 1 1
NQO1 ALOX15 0 0 141 171 1 1
NQO1 TRIM16 0 0 235 271 1 2
NQO1 MAOA 0 0 180 236 1 1
NQO1 MDM2 0 0 471 471 1 2
NQO1 RHOXF2 0 0 60 154 1 1
NQO1 TP53 835 0 978 996 1 2
NQO1 LCN2 0 0 203 203 1 1
NQO1 ADAM33 0 0 359 359 1 1
NQO1 MYL6 0 0 81 202 1 1
NQO1 SLC7A5 0 0 134 185 1 1
NQO1 DDIT3 0 0 335 344 1 2
NQO1 HDAC2 0 0 202 202 1 1
NQO1 NTSR1 0 0 171 171 1 1
NQO1 RNF115 0 0 0 208 1 1
NQO1 HK2 0 0 170 186 1 2
NQO1 GOLIM4 0 0 0 183 1 1
NQO1 CRTAC1 0 0 83 203 1 1
NQO1 ADH1A 0 0 171 186 1 1
NQO1 RAF1 0 0 150 165 1 2
NQO1 VKORC1L1 0 900 60 901 1 1
NQO1 SLC2A2 0 0 97 151 1 1
NQO1 LMNA 0 0 206 304 1 2
NQO1 AGR2 270 0 53 306 1 1
NQO1 APRT 0 0 629 629 1 1
NQO1 ENC1 0 0 138 151 1 1
NQO1 CYBA 0 0 443 443 1 1
NQO1 CCL26 0 0 306 322 1 1
NQO1 MAFF 0 0 403 403 1 1
NQO1 UGT2B28 0 0 49 193 1 1
NQO1 GSTK1 0 0 264 264 1 1
NQO1 TPMT 0 0 271 271 1 1
NQO1 APAF1 0 0 225 224 1 2
NQO1 HDAC6 0 0 212 212 1 2
NQO1 ADH1C 0 0 202 216 1 1
NQO1 HSPA12B 0 0 0 152 1 1
NQO1 RNF126 0 0 46 363 1 1
NQO1 VDAC2 0 0 122 194 1 1
NQO1 PHLDA2 0 0 82 191 1 1
NQO1 STAT3 0 0 325 325 1 2
NQO1 AKR1C4 0 0 96 227 1 1
NQO1 GCLM 0 0 857 895 1 1
NQO1 SERPINH1 0 0 76 180 1 1
NQO1 AKR1B15 0 0 95 226 1 1
NQO1 MSRB3 0 0 112 152 1 1
NQO1 NDUFS1 0 0 134 242 1 1
NQO1 UGT2B10 0 0 124 256 1 1
NQO1 SFPQ 0 0 329 329 1 1
NQO1 MGST2 0 0 170 169 1 1
NQO1 ERN1 0 0 218 218 1 2
NQO1 GGCX 0 900 203 916 1 1
NQO1 XRCC6 0 0 140 174 1 1
NQO1 UBE2D1 270 0 60 300 1 1
NQO1 JMJD7 0 0 0 421 1 1
NQO1 SLC18A2 0 0 160 174 1 1
NQO1 PPARGC1A 0 0 709 709 1 2
NQO1 SDHC 0 0 284 284 1 1
NQO1 PLTP 0 0 0 210 1 1
NQO1 IGF1R 0 0 141 164 1 2
NQO1 MTF1 0 0 164 163 1 1
NQO1 ABCC2 0 0 370 385 1 1
NQO1 IL18 0 0 195 195 1 2
NQO1 STEAP3 0 0 94 155 1 1
NQO1 PARK2 0 0 217 217 1 1
NQO1 UGT2A2 0 0 47 194 1 1
NQO1 PDK1 0 0 141 203 1 2
NQO1 MYC 0 0 391 406 1 2
NQO1 PPIG 0 0 502 502 1 1
NQO1 APEX1 0 0 286 364 1 1
NQO1 ACACA 0 0 174 173 1 1
NQO1 TOP1 0 0 229 260 1 1
NQO1 NR1I3 0 0 335 335 1 1
NQO1 MSRA 0 0 167 172 1 1
NQO1 GPX7 0 0 282 583 1 1
NQO1 P4HB 0 0 162 206 1 2
NQO1 G6PC 0 0 166 165 1 1
NQO1 PARK7 0 0 434 552 1 2
NQO1 XRCC3 0 0 318 317 1 1
NQO1 SOX14 0 0 0 209 1 1
NQO1 NDUFS3 0 0 94 213 1 1
NQO1 FXN 0 0 187 187 1 1
NQO1 TAAR6 0 0 66 164 1 1
NQO1 UBA1 0 0 77 274 1 1
NQO1 UGT3A1 0 0 0 256 1 1
NQO1 SPARCL1 0 0 218 354 1 1
NQO1 SLC2A3 0 0 96 150 1 1
NQO1 SLC6A1 0 0 0 260 1 1
NQO1 TNFRSF12A 0 0 53 153 1 1
NQO1 TOP2A 0 0 143 195 1 1
NQO1 BACH1 0 0 284 298 1 1
NQO1 MAP2K1 0 0 186 186 1 1
NQO1 POR 0 0 469 469 1 2
NQO1 ODC1 0 800 475 890 1 1
NQO1 AREG 0 0 112 186 1 1
NQO1 STK11 0 0 234 234 1 2
NQO1 CYB5A 0 0 363 377 1 1
NQO1 BRCA1 0 0 271 271 1 2
NQO1 CYP3A7 0 0 182 181 1 1
NQO1 RPS19 271 0 43 272 1 1
NQO1 IYD 0 0 0 382 1 1
NQO1 RB1CC1 0 0 325 325 1 2
NQO1 TMCO3 0 0 0 528 1 1
NQO1 NFE2L2 270 0 870 905 1 2
NQO1 BACH2 0 0 213 267 1 1
NQO1 PGAM5 0 0 163 196 1 1
NQO1 VPS52 0 0 278 293 1 1
NQO1 NR3C1 0 0 181 181 1 1
NQO1 HNMT 0 0 387 386 1 1
NQO1 CTGF 0 0 265 293 1 1
NQO1 CYP2B6 0 0 401 400 1 1
NQO1 STX1B 0 0 54 226 1 1
NQO1 SESN2 0 0 241 240 1 2
NQO1 NDUFS7 710 0 81 753 1 1
NQO1 CYP3A5 0 0 294 294 1 1
NQO1 MTR 0 0 146 257 1 1
NQO1 HIST2H3PS2 0 0 314 313 1 1
NQO1 DIABLO 0 0 159 174 1 2
NQO1 HSPA6 0 0 49 160 1 1
NQO1 TFF1 0 0 123 166 1 1
NQO1 BLVRA 0 0 181 181 1 1
NQO1 GPX4 0 0 459 583 1 2
NQO1 TRIM16L 0 0 162 183 1 1
NQO1 ZNF217 0 0 328 328 1 1
NQO1 MAPK8 0 0 294 294 1 2
NQO1 ARG1 0 0 123 152 1 2
NQO1 GCLC 0 0 870 895 1 1
NQO1 BTG3 0 0 74 216 1 1
NQO1 ADIPOQ 0 0 205 205 1 2
NQO1 CENPF 0 0 72 453 1 1
NQO1 KCNS3 0 0 400 400 1 1
NQO1 XRCC1 0 0 468 468 1 1
NQO1 CYP4F11 0 0 180 179 1 1
NQO1 FASN 0 0 180 180 1 2
NQO1 PLAU 0 0 107 484 1 1
NQO1 IL17A 0 0 154 153 1 2
NQO1 OLFM4 0 0 0 214 1 1
NQO1 AKR1B1 0 0 282 386 1 1
NQO1 EGF 0 0 261 261 1 2
NQO1 GADD45B 0 0 151 213 1 1
NQO1 CHEK2 0 0 181 181 1 1
NQO1 CYCS 0 0 467 467 1 2
NQO1 OGG1 0 0 422 422 1 1
NQO1 CASP9 0 0 391 390 1 2
NQO1 PPARA 0 0 376 376 1 2
NQO1 RBM47 0 0 0 212 1 1
NQO1 CBR1 0 0 451 468 1 1
NQO1 LPL 0 0 165 167 1 1
NQO1 ACHE 0 0 166 167 1 2
NQO1 IER3 0 0 167 197 1 1
NQO1 PIF1 0 0 0 260 1 1
NQO1 CHAT 0 0 60 151 1 1
NQO1 HSP90B1 0 0 164 184 1 1
NQO1 HSPB3 0 0 282 282 1 1
NQO1 CYP2E1 0 0 608 608 1 2
NQO1 PDCD4 0 0 96 152 1 2
NQO1 TYR 0 0 161 181 1 2
NQO1 B3GAT2 0 0 338 407 1 1
NQO1 HSPA4 270 0 476 627 1 1
NQO1 CYP1B1 0 0 683 690 1 1
NQO1 CASP7 0 0 160 159 1 1
NQO1 CUL1 0 0 202 202 1 1
NQO1 PHF11 0 0 387 386 1 1
NQO1 DNAJC18 0 0 0 161 1 1
NQO1 CD68 0 0 181 181 1 2
NQO1 CASP8 0 0 282 282 1 2
NQO1 GADD45GIP1 0 0 183 183 1 1
NQO1 ALB 0 0 503 521 1 2
NQO1 CCL2 0 0 394 394 1 2
NQO1 CDC37 0 0 126 278 1 1
NQO1 ABCC3 0 0 416 454 1 1
NQO1 SDHA 0 0 174 175 1 1
NQO1 PMF1 0 0 398 398 1 1
NQO1 CD276 0 0 0 238 1 1
NQO1 TMEM14A 0 0 62 440 1 1
NQO1 IL16 0 0 61 224 1 1
NQO1 ERO1L 0 0 187 187 1 1
NQO1 BLVRB 0 0 150 297 1 1
NQO1 SPARC 0 0 241 302 1 2
NQO1 SMAD3 0 0 194 194 1 2
NQO1 ABCC4 0 0 372 394 1 1
NQO1 CRY2 0 0 61 295 1 1
NQO1 ABCB6 0 0 242 294 1 1
NQO1 IL4 0 0 203 203 1 1
NQO1 AGMAT 0 0 62 308 1 1
NQO1 GPX5 0 0 134 546 1 1
NQO1 EP300 0 0 182 181 1 2
NQO1 PTPRJ 0 0 67 280 1 1
NQO1 IDH1 0 0 205 239 1 1
NQO1 CDH1 0 0 219 219 1 2
NQO1 ALCAM 0 0 63 194 1 1
NQO1 OSGIN1 0 0 282 341 1 1
NQO1 CBR3 0 0 468 501 1 1
NQO1 CDK6 0 0 114 193 1 2
NQO1 ALDH3A2 0 0 150 238 1 1
NQO1 AKR1D1 0 0 81 214 1 1
NQO1 HSPA14 0 0 0 152 1 1
NQO1 CTH 0 0 143 179 1 1
NQO1 SIRT6 270 0 321 486 1 2
NQO1 AKR1E2 0 0 0 180 1 1
NQO1 HYOU1 0 0 91 150 1 1
NQO1 MT1B 0 0 500 499 1 1
NQO1 FECH 0 0 181 181 1 1
NQO1 DGCR14 0 0 0 336 1 1
NQO1 CYP3A4 0 0 454 454 1 1
NQO1 ERCC4 0 0 112 151 1 1
NQO1 MRPS7 0 0 421 420 1 1
NQO1 H2AFX 0 0 212 212 1 1
NQO1 PSMB2 0 0 102 196 1 1
NQO1 IL1A 0 0 233 232 1 1
NQO1 AVP 0 0 150 183 1 1
NQO1 MAF 0 0 654 659 1 1
NQO1 KLHL1 0 0 94 156 1 1
NQO1 ZBTB1 0 0 60 217 1 1
NQO1 SLC3A2 0 0 170 337 1 1
NQO1 FKBP5 0 0 74 175 1 1
NQO1 TSC22D1 0 0 82 280 1 1
NQO1 SIRT7 0 0 275 279 1 2
NQO1 GABARAPL1 0 0 148 241 1 2
NQO1 ICAM1 0 0 342 357 1 2
NQO1 ADH1B 0 0 245 259 1 1
NQO1 HBE1 0 0 156 177 1 1
NQO1 ESR2 0 0 283 282 1 1
NQO1 PTPRC 0 0 119 206 1 1
NQO1 ADH7 0 0 218 249 1 1
NQO1 PLA2G1B 0 0 116 171 1 1
NQO1 AURKA 0 0 90 270 1 2
NQO1 CXCL12 0 0 150 162 1 2
NQO1 TIMP1 0 0 223 255 1 1
NQO1 KIAA1324 0 0 102 161 1 1
NQO1 BAX 0 0 322 321 1 2
NQO1 OAT 0 0 0 181 1 1
NQO1 CHST10 0 0 118 244 1 1
NQO1 NKRF 0 0 505 505 1 1
NQO1 CDKN1A 0 0 324 323 1 2
NQO1 SPP1 0 0 157 175 1 2
NQO1 ERP44 0 0 0 219 1 1
NQO1 TCF7L1 0 0 431 431 1 1
NQO1 NMRAL1 0 0 57 165 1 1
NQO1 PARP1 270 0 391 536 1 2
NQO1 AR 0 0 217 217 1 2
NQO1 GSR 0 0 718 736 1 1
NQO1 INSR 0 0 95 157 1 1
NQO1 HSPA8 0 0 167 316 1 2
NQO1 GLO1 0 0 206 261 1 1
NQO1 SIRT3 0 0 374 377 1 2
NQO1 MAPK3 0 0 341 345 1 2
NQO1 TKTL1 0 0 0 179 1 1
NQO1 KEAP1 0 0 873 892 1 2
NQO1 MMP9 0 0 391 390 1 2
NQO1 B2M 0 0 212 212 1 1
NQO1 DAZAP1 272 0 0 303 1 1
NQO1 F2RL2 0 0 65 207 1 1
NQO1 BNIP3 0 0 211 244 1 2
NQO1 SQSTM1 0 0 520 539 1 2
NQO1 CRYZ 0 0 870 882 1 1
NQO1 DDIAS 0 0 73 218 1 1
NQO1 SLC11A2 0 0 164 170 1 1
NQO1 ALDH3A1 0 0 595 610 1 1
NQO1 ACTB 0 0 654 689 1 2
NQO1 INS 0 0 400 400 1 2
NQO1 DNAJB5 0 0 0 228 1 1
NQO1 STUB1 487 0 194 568 1 2
NQO1 GOT1 272 0 54 354 1 1
NQO1 DNMT1 0 0 265 265 1 2
NQO1 PTGDR2 0 0 385 384 1 1
NQO1 CEBPA 0 0 347 347 1 1
NQO1 UGT1A3 0 0 323 406 1 1
NQO1 COX4I1 0 0 218 218 1 1
NQO1 CRP 0 0 193 200 1 2
NQO1 TP73 653 0 0 653 1 2
NQO1 PSEN1 0 0 162 224 1 2
NQO1 SPDYA 0 0 59 221 1 1
NQO1 HSP90AA1 0 0 468 468 1 2
NQO1 TFEB 0 0 112 200 1 2
NQO1 FOSL1 0 0 245 293 1 1
NQO1 HPGDS 0 0 757 757 1 1
NQO1 ATP8B1 0 0 74 153 1 1
NQO1 GOLGB1 0 0 0 536 1 1
NQO1 MAFB 0 0 81 172 1 1
NQO1 CTDSP2 0 0 0 394 1 1
NQO1 ASF1A 0 0 66 152 1 1
NQO1 JUN 0 0 517 517 1 2
NQO1 ASF1B 0 0 0 151 1 1
NQO1 SLC22A18 0 0 294 326 1 1
NQO1 CORO2B 0 0 53 158 1 1
NQO1 CALB1 0 0 358 358 1 1
NQO1 NRF1 0 0 216 244 1 2
NQO1 MTHFD2 0 0 164 219 1 1
NQO1 FMO4 0 0 146 204 1 1
NQO1 MGST3 0 0 321 335 1 1
NQO1 CCL24 0 0 307 307 1 1
NQO1 POLDIP3 271 0 0 271 1 1
NQO1 CYP19A1 0 0 325 325 1 2
NQO1 BCL2L11 0 0 193 193 1 2
NQO1 ARL14EPL 0 0 122 172 1 1
NQO1 SERPINB2 0 0 92 445 1 1
NQO1 UBA6 0 0 0 179 1 1
NQO1 ABCC5 0 0 261 271 1 1
NQO1 CDC20 0 0 113 155 1 1
NQO1 CAV1 117 0 213 343 1 2
NQO1 GSTA4 0 0 505 542 1 1
NQO1 AIF1 0 0 240 239 1 2
NQO1 HSPA1A 213 0 442 644 1 1
NQO1 COL18A1 0 0 74 199 1 1
NQO1 CGRRF1 0 0 66 227 1 1
NQO1 CASP1 0 0 267 268 1 2
NQO1 NOS1 0 0 167 167 1 1
NQO1 CCNA2 0 0 181 204 1 1
NQO1 DNTT 0 0 294 294 1 1
NQO1 CHEK1 0 0 207 207 1 2
NQO1 NNMT 0 0 113 184 1 1
NQO1 CYP7A1 0 0 220 225 1 1
NQO1 SNCA 0 0 325 325 1 2
NQO1 GIPC3 0 0 57 300 1 1
NQO1 NEIL2 0 0 521 531 1 1
NQO1 SLC47A1 0 0 81 178 1 1
NQO1 CREB3 0 0 216 216 1 1
NQO1 MMP2 0 0 261 283 1 2
NQO1 TLK1 0 0 82 224 1 1
NQO1 PLA2G15 0 0 0 207 1 1
NQO1 TFAM 0 0 295 295 1 2
NQO1 SAT1 0 0 412 415 1 1
NQO1 UCHL1 0 0 142 185 1 2
NQO1 KCNMB1 0 0 330 330 1 1
NQO1 RSAD1 0 0 0 188 1 1
NQO1 MFN1 0 0 123 152 1 2
NQO1 IGFBP3 0 0 151 181 1 2
NQO1 PSMB8 0 0 123 183 1 1
NQO1 UGT1A8 0 0 601 650 1 1
NQO1 PRDX1 0 0 563 610 1 1
NQO1 AIP 0 0 118 175 1 1
NQO1 AKR1C2 0 0 404 509 1 1
NQO1 DNAJC3 0 0 202 266 1 1
NQO1 ARNT 0 0 270 320 1 2
NQO1 LTA 0 0 81 174 1 1
NQO1 SOD1 0 0 632 646 1 2
NQO1 LAMB1 271 0 0 312 1 1
NQO1 VCP 0 0 73 503 1 2
NQO1 NEIL1 0 0 0 189 1 1
NQO1 UGT2B17 0 0 67 208 1 1
NQO1 FST 0 0 86 179 1 1
NQO1 FYN 0 0 277 277 1 1
NQO1 PHGDH 0 0 139 162 1 1
NQO1 MYOF 0 0 123 200 1 1
NQO1 SEPP1 0 0 136 156 1 1
NQO1 GPT 0 0 451 451 1 1
NQO1 WWOX 0 0 268 274 1 1
NQO1 SIRT4 0 0 279 283 1 1
NQO1 PINK1 0 0 246 245 1 2
NQO1 HSP90AB1 0 0 120 309 1 2
NQO1 ALAS1 0 0 124 172 1 1
NQO1 DLD 0 0 181 216 1 2
NQO1 UGT1A9 0 0 390 465 1 1
NQO1 TYMS 0 0 262 276 1 1
NQO1 CXCL10 0 0 155 154 1 2
NQO1 MAFG 0 0 556 556 1 1
NQO1 KRT18 0 0 90 194 1 1
NQO1 EIF4EBP1 0 0 120 152 1 2
NQO1 AIFM1 0 0 94 169 1 1
NQO1 AHSA1 0 0 193 243 1 1
NQO1 GSTA2 0 0 603 615 1 1
NQO1 MAFK 0 0 470 490 1 1
NQO1 NR1I2 0 0 369 369 1 1
NQO1 UGT1A6 0 0 650 693 1 1
NQO1 FOXJ1 0 0 0 165 1 1
NQO1 AHRR 0 0 113 160 1 1
NQO1 ERBB2 0 0 293 310 1 2
NQO1 PMF1-BGLAP 0 0 398 398 1 1
NQO1 NGF 0 0 171 189 1 2
NQO1 PRDX3 0 0 262 305 1 1
NQO1 CD34 0 0 156 155 1 2
NQO1 TH 0 0 212 212 1 2
NQO1 CYP2C19 0 0 284 284 1 1
NQO1 PPARG 0 0 406 419 1 2
NQO1 BHMT 0 0 61 382 1 1
NQO1 AKT1 0 0 560 569 1 2
NQO1 CPT1A 0 0 202 219 1 1
NQO1 GIPC1 0 0 0 159 1 1
NQO1 UGT1A1 0 0 601 650 1 1
NQO1 ERP29 0 0 0 537 1 1
NQO1 IRAK1BP1 0 0 54 246 1 1
NQO1 NDUFA5 0 0 141 194 1 1
NQO1 UBLCP1 0 0 0 364 1 1
NQO1 GGT1 0 0 230 248 1 1
NQO1 CSF2 0 0 155 154 1 1
NQO1 DUSP23 0 0 61 161 1 1
NQO1 CYP8B1 0 0 142 160 1 1
NQO1 SEPW1 0 0 124 163 1 1
NQO1 VCAM1 43 0 321 322 1 1
NQO1 ATF4 0 0 357 357 1 2
NQO1 BHMT2 0 0 46 170 1 1
NQO1 HSPH1 0 0 88 167 1 1
NQO1 ISCU 0 0 0 170 1 1
NQO1 CD4 0 0 181 181 1 2
NQO1 ATP7A 0 0 329 344 1 1
NQO1 SCGB2A1 0 0 398 398 1 1
NQO1 SPATA5 0 0 0 191 1 1
NQO1 DUOX1 0 0 249 248 1 1
NQO1 DNAJB14 0 0 61 179 1 1
NQO1 SLC10A1 0 0 160 165 1 1
NQO1 GSTM1 0 0 735 740 1 1
NQO1 IKBKB 0 0 260 260 1 2
NQO1 FRMD8 0 0 64 163 1 1
NQO1 EPGN 0 0 146 199 1 1
NQO1 ATF6 0 0 261 261 1 2
NQO1 ING1 270 0 214 401 1 1
NQO1 S100A16 0 0 0 151 1 1
NQO1 SPATA5L1 0 0 0 191 1 1
NQO1 NOX4 0 0 459 462 1 2
NQO1 CCDC60 0 0 103 218 1 1
NQO1 RUNX2 0 0 112 306 1 2
NQO1 ASNS 0 0 181 181 1 1
NQO1 XIAP 0 0 178 177 1 2
NQO1 MGST1 0 0 370 400 1 1
NQO1 HMOX1 0 0 912 916 1 2
NQO1 GLRX 0 0 360 364 1 1
NQO1 TAAR9 0 0 48 213 1 1
NQO1 TCHP 0 0 430 430 1 1
NQO1 CYP2C9 0 0 378 378 1 1
NQO1 DNAJC21 0 0 0 161 1 1
NQO1 TOMM20 0 0 155 154 1 2
NQO1 HMMR 0 0 385 404 1 1
NQO1 UGT2B11 0 0 97 233 1 1
NQO1 IL4I1 0 0 74 565 1 1
NQO1 SKP1 0 0 150 172 1 2
NQO1 CLDN4 0 0 126 157 1 1
NQO1 EIF2S1 0 0 194 214 1 2
NQO1 SCGB1A1 0 0 306 306 1 1
NQO1 GLUL 0 0 141 196 1 1
NQO1 TGFB1 0 0 166 218 1 2
NQO1 VDAC1 0 0 201 222 1 2
NQO1 KRT19 0 0 101 161 1 1
NQO1 PPM1D 0 0 243 242 1 1
NQO1 STAT5B 0 0 60 243 1 1
NQO1 RBX1 0 0 455 458 1 1
NQO1 GSTA3 0 0 494 510 1 1
NQO1 HSD17B2 0 0 166 165 1 1
NQO1 OXCT1 0 0 66 175 1 1
NQO1 CYP2D6 0 0 395 394 1 1
NQO1 CDKN1B 0 0 148 171 1 2
NQO1 PGP 0 0 432 443 1 1
NQO1 PRKCD 0 0 282 282 1 2
NQO1 GSTZ1 0 0 289 288 1 1
NQO1 DHCR24 0 0 150 189 1 1
NQO1 GSTM4 0 0 325 614 1 1
NQO1 GALT 299 0 0 299 1 1
NQO1 CRY1 0 0 108 331 1 1
NQO1 FOXO3 0 0 294 299 1 2
NQO1 SLC2A4 0 0 170 220 1 1
NQO1 APOE 0 0 261 261 1 2
NQO1 SCD 0 0 248 275 1 1
NQO1 TTC12 0 0 0 194 1 1
NQO1 SRC 0 0 260 260 1 2
NQO1 DKK1 0 0 66 165 1 1
NQO1 HSPA12A 0 0 0 152 1 1
NQO1 GPX6 0 0 205 469 1 1
NQO1 ATG3 0 0 143 196 1 2
NQO1 DNAJB1 213 0 210 567 1 2
NQO1 JDP2 0 0 150 188 1 1
NQO1 CDKN3 0 0 153 191 1 1
NQO1 SUOX 0 0 45 164 1 1
NQO1 PSMD7 0 0 46 397 1 1
NQO1 PSMB5 0 0 233 264 1 1
NQO1 UGT2B15 0 0 233 349 1 1
NQO1 UGT2B7 0 0 283 391 1 1
NQO1 UGT2B4 0 0 95 232 1 1
NQO1 COMT 0 0 456 456 1 1
NQO1 HNF4A 0 0 181 181 1 1
NQO1 EIF2AK3 0 0 391 390 1 2
NQO1 TP53INP1 0 0 137 163 1 2
NQO1 JMJD7-PLA2G4B 0 0 0 421 1 1
NQO1 FMO2 0 0 150 344 1 1
NQO1 NAT1 0 0 235 235 1 1
NQO1 S100A6 0 0 47 219 1 1
NQO1 ACLY 0 0 157 158 1 1
NQO1 SRXN1 0 0 681 703 1 1
NQO1 RPS6KB1 0 0 202 202 1 2
NQO1 RPS9 0 0 76 177 1 1
NQO1 AHR 0 0 681 688 1 2
NQO1 SERPINE1 0 0 269 312 1 1
NQO1 EIF4E 0 0 95 186 1 2
NQO1 CDK1 0 0 180 209 1 2
NQO1 PGR 0 0 142 160 1 1
NQO1 NOX5 0 0 157 156 1 1
NQO1 GSTA1 0 0 686 696 1 1
NQO1 SESN1 0 0 218 218 1 1
NQO1 HMGCR 0 0 142 161 1 1
NQO1 LOX 0 0 242 275 1 2
NQO1 IRS1 0 0 195 195 1 2
NQO1 HSPA9 0 0 95 190 1 1
NQO1 NCF1 0 0 246 245 1 1
NQO1 ABCG2 0 0 317 332 1 1
NQO1 C8A 0 0 48 253 1 1
NQO1 ANXA2 0 0 60 156 1 1
NQO1 ADH5 0 0 122 174 1 1
NQO1 MTHFR 0 0 454 462 1 1
NQO1 GGTLC1 0 0 143 163 1 1
NQO1 SLC35A2 0 0 505 505 1 1
NQO1 CCND1 0 0 392 450 1 2
NQO1 ALDOC 0 0 74 150 1 1
NQO1 ALDH2 0 0 298 314 1 2
NQO1 DPYD 0 0 202 202 1 1
NQO1 AHNAK 0 0 0 454 1 1
NQO1 JUND 0 0 402 402 1 1
NQO1 NOS3 0 0 391 390 1 2
NQO1 MT1A 0 0 435 435 1 1
NQO1 ACTA2 0 0 89 177 1 1
NQO1 SLCO1B1 0 0 144 197 1 1
NQO1 LDLR 0 0 134 155 1 2
NQO1 TP53I3 0 0 83 193 1 1
NQO1 ACOT13 0 0 0 262 1 1
NQO1 DNAJB12 0 0 48 168 1 1
NQO1 KLF9 0 0 182 200 1 1
NQO1 DNAJB2 0 0 57 175 1 1
NQO1 HPRT1 0 0 240 239 1 1
NQO1 UBFD1 0 0 0 215 1 1
NQO1 HSD17B1 0 0 162 169 1 1
NQO1 AKR1C1 0 0 606 673 1 1
NQO1 BAK1 0 0 61 205 1 2
NQO1 TIMM10B 0 0 74 195 1 1
NQO1 L2HGDH 0 0 66 184 1 1
NQO1 TXN 0 0 654 682 1 1
NQO1 FH 0 0 173 326 1 1
NQO1 DNAJB7 0 0 0 161 1 1
NQO1 FADS1 0 0 122 157 1 1
NQO1 AOX1 0 0 335 350 1 1
NQO1 ENSG00000264813 0 0 172 171 1 1
NQO1 MT1F 0 0 484 483 1 1
NQO1 CAT 0 0 739 760 1 2
NQO1 PECAM1 0 0 161 167 1 1
NQO1 GSTT2B 0 0 405 405 1 1
NQO1 PSMA3 0 0 138 213 1 1
NQO1 SLC19A1 0 0 246 266 1 1
NQO1 NBR1 0 0 107 200 1 2
NQO1 PLA2G2A 0 0 265 265 1 1
NQO1 TNF 114 0 557 609 1 2
NQO1 UGT1A4 0 0 341 422 1 1
NQO1 HSPA2 0 0 0 181 1 1
NQO1 PTMA 0 0 134 218 1 1
NQO1 XDH 0 0 292 341 1 1
NQO1 HSPA13 0 0 50 164 1 1
NQO1 PM20D2 0 0 0 165 1 1
NQO1 BDNF 0 0 259 258 1 2
NQO1 MT1X 0 0 500 506 1 1
NQO1 CD44 0 0 171 171 1 2
NQO1 PLA2G12A 0 0 155 207 1 1
NQO1 PIAS2 0 0 325 325 1 1
NQO1 MMP3 0 0 181 204 1 1
NQO1 PLBD2 0 0 0 179 1 1
NQO1 NME1 681 0 0 699 1 1
NQO1 CES1 0 0 112 155 1 1
NQO1 SCGB3A2 0 0 398 398 1 1
NQO1 HRSP12 0 0 0 181 1 1
NQO1 GLS2 0 0 162 161 1 1
NQO1 RTL1 0 0 0 439 1 1
NQO1 UGT1A10 0 0 390 465 1 1
NQO1 MUC7 0 0 397 396 1 1
NQO1 SLC7A11 0 0 601 627 1 2
NQO1 STIP1 0 0 71 569 1 1
NQO1 MT2A 0 0 398 423 1 1
NQO1 USP14 0 0 49 540 1 2
NQO1 PPP1R15A 0 0 218 218 1 2
NQO1 RPLP0 0 0 161 180 1 1
NQO1 INMT 0 0 225 283 1 1
NQO1 ACMSD 0 0 0 197 1 1
NQO1 CYB5R3 0 0 323 323 1 1
NQO1 TFRC 0 0 170 191 1 1
NQO1 PRDX2 0 0 181 404 1 1
NQO1 IREB2 0 0 161 161 1 1
NQO1 ATP12A 0 0 203 203 1 1
NQO1 GSTP1 0 0 710 721 1 1
NQO1 EDEM1 0 0 135 161 1 2
NQO1 BCAP31 0 0 0 317 1 1
NQO1 GLRX2 0 0 181 186 1 1
NQO1 NFE2L3 0 0 501 502 1 1
NQO1 ABCB10 0 0 0 288 1 1
NQO1 CYP2A6 0 0 323 323 1 1
NQO1 SPOCK1 0 0 180 179 1 1
NQO1 FGF2 0 0 164 163 1 2
NQO1 PRDX4 0 0 184 239 1 1
NQO1 TXNIP 0 0 273 299 1 2
NQO1 ABCC6 0 0 137 197 1 1
NQO1 BCL2A1 0 0 97 292 1 1
NQO1 GSTM5 0 0 261 275 1 1
NQO1 GADD45A 0 0 270 320 1 1
NQO1 ESRRB 0 0 74 196 1 1
NQO1 PKM 0 0 149 180 1 1
NQO1 VKORC1 0 900 431 942 1 1
NQO1 ATF3 0 0 284 284 1 2
NQO1 IGF1 0 0 283 282 1 2
NQO1 ITGA3 0 0 0 176 1 2
NQO1 DNAJC7 0 0 0 222 1 1
NQO1 ANAPC2 0 0 0 190 1 1
NQO1 FABP1 0 0 96 152 1 1
NQO1 THBS2 0 0 52 154 1 1
NQO1 ARNTL 0 0 156 155 1 1
NQO1 HSPB1 0 0 294 328 1 2
NQO1 NCF2 0 0 279 279 1 1
NQO1 TERT 0 0 189 189 1 2
NQO1 HSPB2 0 0 274 274 1 1
NQO1 IPO4 0 0 0 163 1 1
NQO1 ESPN 0 0 0 215 1 1
NQO1 CDC45 0 0 44 168 1 1
NQO1 SUGT1 0 0 0 252 1 1
NQO1 LOR 0 0 161 161 1 1
NQO1 HMOX2 0 0 325 509 1 1
NQO1 CYP2C8 0 0 212 212 1 1
NQO1 SERPINB5 0 0 150 177 1 1
NQO1 ACSM4 0 0 112 192 1 1
NQO1 MAP1LC3B 0 0 280 292 1 2
NQO1 DNAJB8 0 0 0 161 1 1
NQO1 ELANE 0 0 143 235 1 1
NQO1 GPX3 0 0 422 520 1 1
NQO1 PRKCA 0 0 144 161 1 1
NQO1 SOD3 0 0 342 347 1 1
NQO1 NONO 0 0 304 304 1 1
NQO1 ADK 679 0 575 857 1 1
NQO1 TBP 0 0 244 243 1 1
NQO1 FN1 74 0 261 321 1 2
NQO1 GPX1 0 0 661 684 1 1
NQO1 SIRT1 0 0 499 502 1 2
NQO1 MCL1 0 0 167 167 1 2
NQO1 CTSB 0 0 154 153 1 2
NQO1 SULT1E1 0 0 166 195 1 1
NQO1 ACOX1 0 0 138 163 1 1
NQO1 LMNB1 0 0 365 431 1 1
NQO1 NOX1 0 0 408 409 1 1
NQO1 COPS5 0 0 58 404 1 1
NQO1 LIMCH1 0 0 0 300 1 1
NQO1 DUOX2 0 0 235 235 1 1
NQO1 HMGB1 0 0 181 181 1 2
NQO1 ESR1 0 0 486 486 1 2
NQO1 DKK4 0 0 0 190 1 1
NQO1 MAP3K5 0 0 235 235 1 1
NQO1 ITGAM 0 0 188 199 1 1
NQO1 PDK4 0 0 156 217 1 1
NQO1 PAPSS2 0 0 74 231 1 1
NQO1 ERCC6 0 0 113 164 1 1
NQO1 ATG5 0 0 260 260 1 2
NQO1 HTATIP2 0 0 106 185 1 1
NQO1 MT-ND1 0 0 195 230 1 1
NQO1 SLC6A3 0 0 154 153 1 1
NQO1 PTPN1 0 0 150 157 1 1
NQO1 FUBP3 679 0 0 679 1 1
NQO1 MT1G 0 0 491 491 1 1
NQO1 ATP4A 0 0 202 202 1 1
NQO1 SRD5A2 0 0 140 226 1 1
NQO1 TNFAIP2 0 0 107 203 1 1
NQO1 EPHX1 0 0 681 696 1 1
NQO1 KIAA0368 0 0 74 172 1 1
NQO1 TP63 0 900 97 905 1 2
NQO1 XBP1 0 0 252 257 1 2
NQO1 PTEN 0 0 323 323 1 2
NQO1 RPL10A 0 0 51 201 1 1
NQO1 FTL 0 0 395 428 1 1
NQO1 MAGEA4 0 0 0 177 1 1
NQO1 VEGFA 0 0 325 325 1 2
NQO1 ACSL4 0 0 157 156 1 1
NQO1 PLBD1 0 0 52 297 1 1
NQO1 TXN2 0 0 294 306 1 1
NQO1 SLC22A16 0 0 201 201 1 1
NQO1 AASDHPPT 0 0 0 165 1 1
NQO1 FMO3 0 0 282 294 1 1
NQO1 NUDT1 0 0 171 190 1 1
NQO1 NUDT7 0 0 57 154 1 1
NQO1 C12orf5 0 0 181 181 1 1
NQO1 NFE2L1 0 0 372 548 1 1
NQO1 AIMP2 0 0 49 163 1 1
NQO1 NFKBIA 0 0 422 432 1 2
NQO1 HFE 0 0 146 199 1 1
NQO1 LEP 0 0 212 212 1 1
NQO1 ATAD2B 0 0 0 193 1 1
NQO1 LDHA 0 0 242 280 1 2
NQO1 AKR7A2 0 0 274 436 1 1
NQO1 SREBF1 0 0 310 309 1 1
NQO1 UCP1 0 0 135 158 1 2
NQO1 PAPSS1 0 0 0 163 1 1
NQO1 NDUFA9 0 0 123 237 1 1
NQO1 CYP2S1 0 0 202 202 1 1
NQO1 MAPK14 0 0 182 268 1 2
NQO1 ENSG00000258947 0 0 75 162 1 1
NQO1 LMNB2 0 0 127 153 1 1
NQO1 ATM 0 0 254 254 1 2
NQO1 MTRR 0 0 195 195 1 1
NQO1 SULT2B1 0 0 252 252 1 1
NQO1 CYGB 0 0 181 186 1 1
NQO1 CTSD 0 0 115 180 1 2
NQO1 TTC28 0 0 0 194 1 1
NQO1 GOT2 0 0 306 306 1 1
NQO1 BCAP29 0 0 0 187 1 1
NQO1 RAD23B 0 0 88 185 1 1
NQO1 G6PD 0 0 503 548 1 1
NQO1 TXNDC17 0 0 0 160 1 1
NQO1 DNAJB13 0 0 0 228 1 1
NQO1 ENSG00000270386 0 0 48 194 1 1
NQO1 LCAT 0 0 55 402 1 1
NQO1 OR2AK2 0 0 0 188 1 1
NQO1 GDF15 0 0 181 299 1 1
NQO1 NR1H4 0 0 245 244 1 1
NQO1 ACTG1 0 0 237 284 1 1
NQO1 TJP1 0 0 219 252 1 1
NQO1 SELE 0 0 167 167 1 1
NQO1 FOSB 0 0 123 152 1 1
NQO1 ATG7 0 0 322 321 1 2
NQO1 RPS3A 0 0 70 282 1 1
NQO1 NAMPT 0 0 202 202 1 2
NQO1 PPARGC1B 0 0 164 176 1 1
NQO1 COL1A1 0 0 182 211 1 2
NQO1 CXCL2 0 0 171 183 1 1
NQO1 OAZ2 0 0 142 195 1 1
NQO1 PTGR1 0 0 356 458 1 1
NQO1 GSTA5 0 0 321 342 1 1
NQO1 GFAP 0 0 238 237 1 2
NQO1 MT-ND4 0 0 74 215 1 1
NQO1 UBE2S 0 0 96 152 1 1
NQO1 UGT1A5 0 0 381 457 1 1
NQO1 UGT1A7 0 0 374 451 1 1
NQO1 IL10 0 0 334 343 1 2
NQO1 ACO1 0 0 135 156 1 1
NQO1 HDAC1 0 0 226 225 1 2
NQO1 RRM2 0 0 122 165 1 1
NQO1 TXNRD2 0 0 234 267 1 1
NQO1 ETFB 0 0 0 161 1 1
NQO1 DHFR 0 0 182 181 1 1
NQO1 TXNRD1 0 0 710 761 1 1
NQO1 CEBPB 0 0 180 179 1 2
NQO1 ZADH2 0 0 0 163 1 1
NQO1 PDIA4 0 0 134 187 1 1
NQO1 PI4KA 0 0 57 152 1 1
NQO1 CUL3 0 0 681 688 1 2
NQO1 CHUK 0 0 231 230 1 1
NQO1 NDUFS8 0 0 102 167 1 1
NQO1 CCNG1 0 0 149 213 1 1
NQO1 GPX8 0 0 180 581 1 1
NQO1 GSK3B 0 0 235 306 1 2
NQO1 CDKN2A 0 0 266 267 1 2
NQO1 ERCC1 0 0 193 248 1 1
NQO1 SPRR2D 0 0 244 243 1 1
NQO1 GUSB 0 0 325 341 1 1
NQO1 FABP4 0 0 194 194 1 1
NQO1 PTGR2 0 0 0 163 1 1
NQO1 UGT2A1 0 0 0 189 1 1
NQO1 TIPARP 0 0 325 396 1 1
NQO1 DPEP1 0 0 45 397 1 1
NQO1 MT1H 0 0 500 499 1 1
NQO1 CYBB 0 0 458 462 1 2
NQO1 CRYM 0 0 0 186 1 1
NQO1 NDE1 0 0 71 170 1 1
NQO1 REN 0 0 167 167 1 1
NQO1 IL13 0 0 143 162 1 2
NQO1 ACE 0 0 184 183 1 1
NQO1 ALOX5 0 0 212 212 1 1
NQO1 HSPA4L 0 0 95 178 1 1
NQO1 PTGS2 0 0 506 506 1 2
NQO1 PSMB9 0 0 66 160 1 1
NQO1 TEX9 0 0 88 228 1 1
NQO1 CASP3 0 0 595 596 1 2
NQO1 AFP 0 0 123 169 1 2
NQO1 CDC27 0 0 453 457 1 1
NQO1 DNAJC22 0 0 0 161 1 1
NQO1 DAXX 0 0 72 168 1 1
NQO1 RGN 0 0 137 171 1 1
NQO1 LMO7 0 0 0 454 1 1
NQO1 NLRP3 0 0 317 317 1 2
NQO1 REL 0 0 156 155 1 2
NQO1 BRCA2 0 0 157 156 1 1
NQO1 HSPA1B 0 0 57 266 1 1
NQO1 PSMB6 0 0 181 308 1 1
NQO1 PLA2G7 0 0 398 398 1 1
NQO1 DTYMK 0 0 60 185 1 1
NQO1 CXCL1 0 0 193 204 1 2
NQO1 ESRRG 0 0 94 156 1 1
NQO1 TRIB3 0 0 171 195 1 2
NQO1 PDIA3 0 0 92 181 1 1
NQO1 GSS 0 0 95 155 1 1
NQO1 LPIN1 0 0 122 156 1 2
NQO1 DNAJB9 0 0 123 233 1 2
NQO1 PSMD2 270 0 0 287 1 1
NQO1 SLC40A1 0 0 194 211 1 1
NQO1 ENOX1 0 0 143 175 1 1
NQO1 SRD5A1 0 0 124 172 1 1
NQO1 GSTM2 0 0 561 605 1 1
NQO1 MET 0 0 113 176 1 2
NQO1 TLR2 0 0 173 173 1 2
NQO1 DNAJC10 0 0 0 150 1 1
NQO1 PMAIP1 0 0 193 193 1 2
NQO1 ABCC1 0 0 346 392 1 1
NQO1 ALDH1A1 0 0 260 277 1 1
NQO1 FMO5 0 0 123 177 1 1
NQO1 IL2 0 0 148 166 1 1
NQO1 DNAJB6 0 0 57 175 1 1
NQO1 TUT1 0 0 124 213 1 1
NQO1 PTGES 0 0 134 154 1 1
NQO1 THBS1 0 0 66 196 1 1
NQO1 ABCB1 0 0 378 378 1 2
NQO1 DSCR3 0 0 53 150 1 1
NQO1 MAOB 0 0 261 312 1 1
NQO1 MYO16 0 0 51 255 1 1
NQO1 BECN1 0 0 287 286 1 2
NQO1 MAPT 0 0 180 179 1 2
NQO1 TKT 0 0 268 307 1 1
NQO1 GPX2 0 0 651 686 1 1
NQO1 CYP2A13 0 0 204 204 1 1
NQO1 YTHDF1 271 0 0 275 1 1
NQO1 SOD2 0 0 633 647 1 2
NQO1 FOXO1 0 0 244 243 1 2
NQO1 PGD 0 0 261 283 1 1
NQO1 KRAS 0 0 325 339 1 2
NQO1 BTRC 0 0 283 282 1 1
NQO1 FTH1 0 0 502 538 1 1
NQO1 HSPA5 0 0 360 417 1 2
NQO1 AKR1A1 0 0 337 433 1 1
NQO1 QPRT 0 0 134 165 1 1
NQO1 AJUBA 0 0 0 229 1 1
NQO1 RXRA 0 0 112 153 1 1
NQO1 STAT5A 0 0 52 152 1 1
NQO1 PON1 0 0 324 323 1 1
NQO1 HNRNPA0 0 0 47 154 1 1
NQO1 NAT2 0 0 277 277 1 1
NQO1 FOS 270 0 391 536 1 2
NQO1 CYP3A43 0 0 167 167 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0003955 Molecular Function NAD(P)H dehydrogenase (quinone) activity enables IBA
GO:0050136 Molecular Function NADH dehydrogenase (quinone) activity enables IDA
GO:0008753 Molecular Function NADPH dehydrogenase (quinone) activity enables IEA
GO:0003723 Molecular Function RNA binding enables HDA
GO:0004128 Molecular Function cytochrome-b5 reductase activity, acting on NAD(P)H enables TAS
GO:0042802 Molecular Function identical protein binding enables IPI
GO:0005515 Molecular Function protein binding enables IPI
GO:0004784 Molecular Function superoxide dismutase activity enables IEA
GO:0006116 Biological Process NADH oxidation involved_in IEA
GO:0070995 Biological Process NADPH oxidation involved_in IEA
GO:0045454 Biological Process cell redox homeostasis involved_in IEP
GO:0070301 Biological Process cellular response to hydrogen peroxide involved_in IEA
GO:0071248 Biological Process cellular response to metal ion involved_in IEA
GO:0034599 Biological Process cellular response to oxidative stress involved_in IDA
GO:0045087 Biological Process innate immune response involved_in IEA
GO:0043066 Biological Process negative regulation of apoptotic process involved_in IEA
GO:0042177 Biological Process negative regulation of protein catabolic process involved_in IDA
GO:0006809 Biological Process nitric oxide biosynthetic process involved_in TAS
GO:0043525 Biological Process positive regulation of neuron apoptotic process involved_in IEA
GO:0030163 Biological Process protein catabolic process involved_in IEA
GO:0000209 Biological Process protein polyubiquitination involved_in IEA
GO:0019430 Biological Process removal of superoxide radicals involved_in IDA
GO:1904844 Biological Process response to L-glutamine involved_in IEA
GO:0043279 Biological Process response to alkaloid involved_in IEA
GO:0014075 Biological Process response to amine involved_in IEA
GO:0009743 Biological Process response to carbohydrate involved_in IEA
GO:0051602 Biological Process response to electrical stimulus involved_in IEA
GO:0032355 Biological Process response to estradiol involved_in IEA
GO:0045471 Biological Process response to ethanol involved_in IEA
GO:1905395 Biological Process response to flavonoid involved_in IEA
GO:0009725 Biological Process response to hormone involved_in IEA
GO:1904880 Biological Process response to hydrogen sulfide involved_in IEA
GO:0002931 Biological Process response to ischemia involved_in IEA
GO:0032496 Biological Process response to lipopolysaccharide involved_in IEA
GO:0007584 Biological Process response to nutrient involved_in IEA
GO:0006979 Biological Process response to oxidative stress involved_in IEP
GO:0033574 Biological Process response to testosterone involved_in IEA
GO:1904772 Biological Process response to tetrachloromethane involved_in IEA
GO:0009636 Biological Process response to toxic substance involved_in TAS
GO:0007271 Biological Process synaptic transmission, cholinergic involved_in TAS
GO:0006743 Biological Process ubiquinone metabolic process involved_in IDA
GO:0042360 Biological Process vitamin E metabolic process involved_in IDA
GO:0042373 Biological Process vitamin K metabolic process involved_in IDA
GO:0006805 Biological Process xenobiotic metabolic process involved_in TAS
GO:0005737 Cellular Component cytoplasm located_in TAS
GO:0005829 Cellular Component cytosol is_active_in IBA
GO:0005829 Cellular Component cytosol located_in IDA
GO:0005829 Cellular Component cytosol located_in TAS
GO:0030425 Cellular Component dendrite located_in IEA
GO:0043025 Cellular Component neuronal cell body located_in IEA
GO:0005634 Cellular Component nucleus located_in IEA
GO:0045202 Cellular Component synapse located_in IEA
Pathways
Name DB ID
Metabolism Reactome R-HSA-1430728
Cellular responses to stress Reactome R-HSA-2262752
Regulation of ornithine decarboxylase (ODC) Reactome R-HSA-350562
Metabolism of polyamines Reactome R-HSA-351202
Metabolism of amino acids and derivatives Reactome R-HSA-71291
Cellular responses to stimuli Reactome R-HSA-8953897
Cellular response to chemical stress Reactome R-HSA-9711123
KEAP1-NFE2L2 pathway Reactome R-HSA-9755511
Nuclear events mediated by NFE2L2 Reactome R-HSA-9759194
NFE2L2 regulating anti-oxidant/detoxification enzymes Reactome R-HSA-9818027
Transcriptional activation by NRF2 in response to phytochemicals (WP3) WikiPathways WP3_r120028
NRF2-ARE regulation (WP4357) WikiPathways WP4357_r98705
Apoptosis-related network due to altered Notch3 in ovarian cancer (WP2864) WikiPathways WP2864_r108133
Vitamin K metabolism and activation of dependent proteins (WP5186) WikiPathways WP5186_r123700
Dopamine metabolism (WP2436) WikiPathways WP2436_r107129
Interactions between LOXL4 and oxidative stress pathway (WP3670) WikiPathways WP3670_r117829
Oxidative stress response (WP408) WikiPathways WP408_r116900
Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling (WP3612) WikiPathways WP3612_r106540
Aryl hydrocarbon receptor pathway (WP2586) WikiPathways WP2586_r121728
Nuclear receptors meta-pathway (WP2882) WikiPathways WP2882_r120815
Aryl hydrocarbon receptor pathway (WP2873) WikiPathways WP2873_r123110
NRF2 pathway (WP2884) WikiPathways WP2884_r106658
Antiviral and anti-inflammatory effects of Nrf2 on SARS-CoV-2 pathway (WP5113) WikiPathways WP5113_r124660
Estrogen metabolism (WP697) WikiPathways WP697_r106826
Male infertility (WP4673) WikiPathways WP4673_r119920
Benzene metabolism (WP3891) WikiPathways WP3891_r106161
Transcripts
Accession Version MolecularType Name NCBI Comments
NM_001286137 2 mRNA transcript variant 4 NC_000016 Reference
NM_001025434 2 mRNA transcript variant 3 NC_000016 Reference
NM_001025433 2 mRNA transcript variant 2 NC_000016 Reference
NM_000903 3 mRNA transcript variant 1 NC_000016 Reference