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E2F1

E2F transcription factor 1
General Information
Name E2F transcription factor 1
Alias
  • transcription factor E2F1
  • PBR3
  • PRB-binding protein E2F-1
  • RBAP-1
  • RBBP-3
  • retinoblastoma-associated protein 1
  • retinoblastoma-binding protein 3
  • retinoblastoma-binding protein 3 (E2F-like)
Gene_family E2F transcription factors
organism Homo sapiens
entrez_id 1869
location 20q11.22
transcript_count 2
exon_count 7
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis. [provided by RefSeq, Jul 2008]
    Stringdb Transcription factor E2F1; Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC- 3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis. Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA bind [...]
    nextProt Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication (PubMed:10675335, PubMed:12717439, PubMed:17704056, PubMed:17050006, PubMed:18625225, PubMed:28992046). The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase (PubMed:10675335, PubMed:12717439, PubMed:17704056). E2F1 binds preferentially RB1 in a cell-cycle dependent manner (PubMed:10675335, PubMed:12717439, PubMed:17704056). It can mediate both cell proliferation and TP53/p53-dependent apoptosis (PubMed:8170954). Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA binding to its target gene promoters (PubMed:20176812). Directly activates transcription of PEG10 (PubMed:17050006, PubMed:18625225, PubMed:28992046). Positively regulates transcription of RRP1B (PubMed:20040599).
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
E2F1 BioGRID RB1 GeneID BioGRID Affinity Capture-Luminescence; Affinity Capture-MS; Affinity Capture-Western; Co-crystal Structure; Co-fractionation; Co-localization; Proximity Label-MS; Reconstituted Complex; Two-hybrid
E2F1 BioGRID KAT2A GeneID BioGRID Affinity Capture-Western; Proximity Label-MS
E2F1 BioGRID SZRD1P1 GeneID BioGRID Affinity Capture-RNA; Protein-RNA
E2F1 BioGRID BAP1 GeneID BioGRID Affinity Capture-Western; Proximity Label-MS
E2F1 BioGRID TOPBP1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
E2F1 BioGRID SGF29 GeneID BioGRID Proximity Label-MS
E2F1 BioGRID EPC1 GeneID BioGRID Proximity Label-MS
E2F1 BioGRID GATAD1 GeneID BioGRID Proximity Label-MS
E2F1 BioGRID PHF12 GeneID BioGRID Proximity Label-MS
E2F1 BioGRID KAT14 GeneID BioGRID Proximity Label-MS
E2F1 BioGRID EMSY GeneID BioGRID Proximity Label-MS
E2F1 BioGRID YEATS2 GeneID BioGRID Proximity Label-MS
E2F1 BioGRID MBIP GeneID BioGRID Proximity Label-MS
E2F1 BioGRID NOP16 GeneID BioGRID Proximity Label-MS
E2F1 BioGRID ZZZ3 GeneID BioGRID Proximity Label-MS
E2F1 BioGRID BRD4 GeneID BioGRID Co-crystal Structure
E2F1 BioGRID CCNA2 GeneID BioGRID Affinity Capture-Western; Proximity Label-MS; Reconstituted Complex
E2F1 BioGRID TADA3 GeneID BioGRID Proximity Label-MS
E2F1 BioGRID KAT2B GeneID BioGRID Affinity Capture-Western; Proximity Label-MS
E2F1 BioGRID TFDP2 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
E2F1 BioGRID TFDP1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-localization; Proximity Label-MS; Reconstituted Complex; Two-hybrid
E2F1 BioGRID TADA2A GeneID BioGRID Proximity Label-MS
E2F1 BioGRID RPL34 GeneID BioGRID Proximity Label-MS
E2F1 BioGRID E2F3 GeneID BioGRID Affinity Capture-MS; Co-localization; Proximity Label-MS
E2F1 BioGRID PTEN GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID USP11 GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID CDK7 GeneID BioGRID Affinity Capture-Western; Co-localization
E2F1 BioGRID CDC6 GeneID BioGRID Co-localization
E2F1 BioGRID PSMD14 GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID DDX5 GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID MDM2 GeneID BioGRID Affinity Capture-RNA; Affinity Capture-Western; Biochemical Activity
E2F1 BioGRID E2F2 GeneID BioGRID Affinity Capture-MS; Co-localization
E2F1 BioGRID PCGF6 GeneID BioGRID Affinity Capture-MS
E2F1 BioGRID E2F6 GeneID BioGRID Affinity Capture-MS
E2F1 BioGRID E2F5 GeneID BioGRID Affinity Capture-MS
E2F1 BioGRID E2F4 GeneID BioGRID Affinity Capture-MS
E2F1 BioGRID MKRN2 GeneID BioGRID Affinity Capture-RNA
E2F1 BioGRID ZBTB7A GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID MYC GeneID BioGRID Affinity Capture-MS
E2F1 BioGRID E7 GeneID BioGRID Affinity Capture-MS; Reconstituted Complex
E2F1 BioGRID MBTPS1 GeneID BioGRID Negative Genetic
E2F1 BioGRID PML GeneID BioGRID Positive Genetic
E2F1 BioGRID JAK1 GeneID BioGRID Negative Genetic
E2F1 BioGRID IL1R1 GeneID BioGRID Negative Genetic
E2F1 BioGRID BIN1 GeneID BioGRID Affinity Capture-Western; Co-localization; Reconstituted Complex
E2F1 BioGRID NBN GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID CCNF GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID DCAF4 GeneID BioGRID Affinity Capture-MS
E2F1 BioGRID EZH2 GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID BIRC2 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
E2F1 BioGRID MCPH1 GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID MCPH1 GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID DIABLO GeneID BioGRID Protein-peptide
E2F1 BioGRID UL123 GeneID BioGRID Biochemical Activity
E2F1 BioGRID L3MBTL3 GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID DCAF5 GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID TP53 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
E2F1 BioGRID RBL1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
E2F1 BioGRID E2F1 GeneID BioGRID Co-localization
E2F1 BioGRID CDKN2A GeneID BioGRID Affinity Capture-Western; Co-localization; Reconstituted Complex
E2F1 BioGRID CDKN1C GeneID BioGRID Affinity Capture-Western; Co-localization
E2F1 BioGRID CDK2 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
E2F1 BioGRID AHR GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID SMARCA2 GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID TRRAP GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID RBL2 GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID EP300 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
E2F1 BioGRID MTA1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
E2F1 BioGRID GABPB1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
E2F1 BioGRID PTPN11 GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID MAGEA11 GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID SKP2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
E2F1 BioGRID HIRA GeneID BioGRID Co-localization
E2F1 BioGRID UBN1 GeneID BioGRID Co-localization
E2F1 BioGRID ASF1A GeneID BioGRID Co-localization
E2F1 BioGRID RING1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
E2F1 BioGRID CUL2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
E2F1 BioGRID PURA GeneID BioGRID Reconstituted Complex
E2F1 BioGRID SV40gp6 GeneID BioGRID Affinity Capture-RNA
E2F1 BioGRID FZR1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
E2F1 BioGRID UBE3A GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
E2F1 BioGRID HDAC1 GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID UCHL5 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
E2F1 BioGRID RNF126 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
E2F1 BioGRID XIAP GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID BRMS1 GeneID BioGRID Two-hybrid
E2F1 BioGRID UBC GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID SIRT1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
E2F1 BioGRID CDH1 GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID CDC20 GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID CDC27 GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID MOV10 GeneID BioGRID Affinity Capture-RNA
E2F1 BioGRID CREBBP GeneID BioGRID Reconstituted Complex; Two-hybrid
E2F1 BioGRID ANAPC11 GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID ANAPC7 GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID ANAPC5 GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID NXF1 GeneID BioGRID Affinity Capture-RNA
E2F1 BioGRID BTRC GeneID BioGRID Biochemical Activity
E2F1 BioGRID KDM2A GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
E2F1 BioGRID LAMTOR5 GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID VHL GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
E2F1 BioGRID RARA GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
E2F1 BioGRID STAT1 GeneID BioGRID Reconstituted Complex
E2F1 BioGRID NCOR2 GeneID BioGRID Reconstituted Complex
E2F1 BioGRID STOML1 GeneID BioGRID Reconstituted Complex
E2F1 BioGRID UHRF2 GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID GTF2H1 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
E2F1 BioGRID ERCC3 GeneID BioGRID Reconstituted Complex
E2F1 BioGRID SPT15 GeneID BioGRID Reconstituted Complex
E2F1 BioGRID TFB1 GeneID BioGRID Reconstituted Complex
E2F1 BioGRID TBP GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
E2F1 BioGRID NCOA3 GeneID BioGRID Affinity Capture-Western; Co-localization; Reconstituted Complex
E2F1 BioGRID CEBPE GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
E2F1 BioGRID PARP1 GeneID BioGRID Co-localization; Reconstituted Complex
E2F1 BioGRID PRMT2 GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID CCNE1 GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID CEBPD GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID CDK1 GeneID BioGRID Biochemical Activity
E2F1 BioGRID DDB2 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
E2F1 BioGRID DDB1 GeneID BioGRID Affinity Capture-MS
E2F1 BioGRID BIRC3 GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID SETD7 GeneID BioGRID Biochemical Activity
E2F1 BioGRID TRIM28 GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID NRIP1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
E2F1 BioGRID ESR1 GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID BRCA1 GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID AR GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID TRIM16 GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID IGF1 GeneID BioGRID Two-hybrid
E2F1 BioGRID KDM1A GeneID BioGRID Biochemical Activity
E2F1 BioGRID CSNK1A1 GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID ATAD2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
E2F1 BioGRID ATR GeneID BioGRID Biochemical Activity
E2F1 BioGRID ATM GeneID BioGRID Biochemical Activity
E2F1 BioGRID PRDM2 GeneID BioGRID Reconstituted Complex
E2F1 BioGRID HCFC1 GeneID BioGRID Affinity Capture-Western; Two-hybrid
E2F1 BioGRID ASH2L GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID CUL1 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
E2F1 BioGRID LEF1 GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID SP1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
E2F1 BioGRID PHB1 GeneID BioGRID Affinity Capture-Western; Co-localization; Reconstituted Complex
E2F1 BioGRID KAT5 GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID CDKN1A GeneID BioGRID Co-localization
E2F1 BioGRID KLF6 GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID YWHAQ GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
E2F1 BioGRID BRD2 GeneID BioGRID Affinity Capture-Western; Co-purification
E2F1 BioGRID CCNA1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
E2F1 Protein SERTAD2 GeneID HPRD
E2F1 Protein CDK7 GeneID HPRD
E2F1 Protein NPDC1 GeneID HPRD
E2F1 Protein ARID3A GeneID HPRD
E2F1 Protein TOPBP1 GeneID HPRD
E2F1 Protein ATR GeneID HPRD
E2F1 Protein ATM GeneID HPRD
E2F1 Protein NCOA6 GeneID HPRD
E2F1 Protein TP53BP1 GeneID HPRD
E2F1 Protein CTDP1 GeneID HPRD
E2F1 Protein CHEK2 GeneID HPRD
E2F1 Protein CCNA1 GeneID HPRD
E2F1 Protein CUL1 GeneID HPRD
E2F1 Protein TRRAP GeneID HPRD
E2F1 Protein E2F6 GeneID HPRD
E2F1 Protein MDM4 GeneID HPRD
E2F1 Protein MNAT1 GeneID HPRD
E2F1 Protein TFDP2 GeneID HPRD
E2F1 Protein NDN GeneID HPRD
E2F1 Protein NCOA3 GeneID HPRD
E2F1 Protein SP3 GeneID HPRD
E2F1 Protein SP2 GeneID HPRD
E2F1 Protein BRD2 GeneID HPRD
E2F1 Protein SKP2 GeneID HPRD
E2F1 Protein KAT5 GeneID HPRD
E2F1 Protein DDB2 GeneID HPRD
E2F1 Protein CEBPE GeneID HPRD
E2F1 Protein SP4 GeneID HPRD
E2F1 Protein PURA GeneID HPRD
E2F1 Protein CDKN2A GeneID HPRD
E2F1 Protein CREBBP GeneID HPRD
E2F1 Protein TP53 GeneID HPRD
E2F1 Protein GTF2H1 GeneID HPRD
E2F1 Protein SP1 GeneID HPRD
E2F1 Protein TFDP1 GeneID HPRD
E2F1 Protein RB1 GeneID HPRD
E2F1 Protein PHB1 GeneID HPRD
E2F1 Protein PARP1 GeneID HPRD
E2F1 Protein NFKB1 GeneID HPRD
E2F1 Protein CCNA2 GeneID HPRD
E2F1 Protein CDK3 GeneID HPRD
E2F1 Protein CDK1 GeneID HPRD
E2F1 Protein BRCA1 GeneID HPRD
E2F1 BioGRID GSK3B GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID Sp1 GeneID BioGRID Reconstituted Complex
E2F1 BioGRID NDN GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
E2F1 BioGRID Nfkb1 GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID NPDC1 GeneID BioGRID Reconstituted Complex; Two-hybrid
E2F1 BioGRID RNF144A GeneID BioGRID Two-hybrid
E2F1 BioGRID SP4 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
E2F1 BioGRID SP3 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
E2F1 BioGRID SP2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
E2F1 BioGRID NFKB1 GeneID BioGRID Reconstituted Complex
E2F1 BioGRID FHL2 GeneID BioGRID Two-hybrid
E2F1 BioGRID ARID3A GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
E2F1 BioGRID MDM4 GeneID BioGRID Reconstituted Complex; Two-hybrid
E2F1 BioGRID TP53BP1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
E2F1 BioGRID RBBP4 GeneID BioGRID Affinity Capture-Western
E2F1 BioGRID DNMT1 GeneID BioGRID Co-fractionation
E2F1 BioGRID MGA GeneID BioGRID Two-hybrid
E2F1 BioGRID TEAD3 GeneID BioGRID Two-hybrid
E2F1 BioGRID SPIB GeneID BioGRID Two-hybrid
E2F1 BioGRID PKIB GeneID BioGRID Two-hybrid
E2F1 BioGRID MYBL2 GeneID BioGRID Two-hybrid
E2F1 BioGRID NSMCE3 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
E2F1 BioGRID NCOA6 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
E2F1 Protein RB1 GeneID BIND pRB interacts with E2F-1.
E2F1 Protein MDM4 GeneID BIND E2F-1 interacts with MDMX. This interaction was modeled on a demonstrated interaction between human E2F-1 and mouse MDMX.
E2F1 Protein CEBPD GeneID BIND C/EBP-delta interacts with E2F1.
E2F1 Nucleotide E2F4 GeneID BIND E2F4 interacts with the E2F1 promoter region.
E2F1 Protein EAPP GeneID BIND E2F1 interacts with EAPP.
E2F1 Protein None None BIND E2F-1 interacts with the E2F site. This interaction was modelled on a demonstrated interaction between E2F-1 and a synthetic dsDNA construct.
E2F1 Protein MYBL2 GeneID BIND E2F1 interacts with the B-myb promoter region.
E2F1 Nucleotide RBL2 GeneID BIND p130 interacts with the E2F1 promoter region.
E2F1 Protein MSH2 GeneID BIND The 5'MSH2 promoter region interacts with E2F1.
E2F1 Protein RB1 GeneID BIND pRb interacts with E2F1.
E2F1 Protein CEBPE GeneID BIND E2F-1 interacts with C/EBPepsilon.
E2F1 Protein BIRC5 GeneID BIND E2F1 (E2F-1) interacts with the BIRC5 (survivin) promoter.
E2F1 Protein MYC GeneID BIND E2F-1 interacts with the MYC gene P2 promoter region.
E2F1 Protein RBL2 GeneID BIND E2F-1 interacts with p130.
E2F1 Protein GAB2 GeneID BIND The Gab2 promoter region interacts with E2F1.
E2F1 Protein BRCA1 GeneID BIND BRCA1 associates with E2F-1
E2F1 Protein CDKN2A GeneID BIND p14ARF interacts with E2F-1.
E2F1 Protein TFDP1 GeneID BIND E2F1 interacts with DP1.
E2F1 Protein RB1 GeneID BIND pRB interacts with E2F1.
E2F1 Nucleotide E2F2 GeneID BIND E2F2 interacts with the E2F1 promoter region.
E2F1 Protein CDC6 GeneID BIND E2F1 interacts with the Cdc6 promoter region.
E2F1 Protein RBL1 GeneID BIND E2F1 interacts with the p107 promoter region.
E2F1 Protein CDK1 GeneID BIND E2F1 interacts with the Cdc2 promoter.
E2F1 Protein CDC25A GeneID BIND E2F1 interacts with the Cdc25A promoter region.
E2F1 Protein E2F1 GeneID BIND E2F1 interacts with the E2F1 promoter region.
E2F1 Protein UXT GeneID BIND E2F1 interacts with the UXT chromatin.
E2F1 Protein FHL2 GeneID BIND E2F1 interacts with a molecule expressed by Gene FHL2. The precise molecular variant of FHL2 involved in this interaction is not specified.
E2F1 Protein TP53INP1 GeneID BIND E2F1 interacts with the TP53INP1 promoter.
E2F1 Protein PPP1R13B GeneID BIND E2F1 interacts with the PPP1R13B (ASPP1) promoter.
E2F1 Protein TP53BP2 GeneID BIND E2F1 interacts with the TP53BP2 (ASPP2) promoter.
E2F1 Protein JMY GeneID BIND E2F1 interacts with the JMY promoter.
E2F1 Protein TP53BP2 GeneID BIND E2F1 (E2F-1) interacts with the TP53BP2 (ASPP2) promoter.
E2F1 Protein PPP1R13B GeneID BIND E2F1 (E2F-1) interacts with the PPP1R13B (ASPP1) promoter.
E2F1 Protein MFAP1 GeneID BIND E2F1 interacts with MFAP1 chromatin.
E2F1 Protein CBX5 GeneID BIND E2F1 interacts with HP1-alpha chromatin.
E2F1 Protein H4C14 GeneID BIND E2F1 interacts with the H4F2 chromatin.
E2F1 Protein RAD51 GeneID BIND E2F1 interacts with the RAD51 chromatin.
E2F1 Protein YBX3 GeneID BIND E2F1 interacts with the DBPA chromatin.
E2F1 Protein Z57695.1 Nucleotide BIND E2F1 interacts with the CpG18G8 chromatin.
E2F1 Protein Z55309.1 Nucleotide BIND E2F1 interacts with the CpG32C1 chromatin.
E2F1 Protein Z56578.1 Nucleotide BIND E2F1 interacts with the CpG12B10 chromatin.
E2F1 Protein RECQL GeneID BIND E2F1 interacts with the RECQL chromatin.
E2F1 Protein PRR11 GeneID BIND E2F1 interacts with the FLJ11029 chromatin.
E2F1 Protein GAS2L1 GeneID BIND E2F1 interacts with the GAR22 chromatin.
E2F1 Protein TRMT13 GeneID BIND E2F1 interacts with the FLJ10287 chromatin.
E2F1 Protein TYMS GeneID BIND E2F1 interacts with the TYMS chromatin.
E2F1 Protein H2BC11 GeneID BIND E2F1 interacts with the H2B chromatin.
E2F1 Protein H2AC11 GeneID BIND E2F1 interacts with the H2A chromatin.
E2F1 Protein TTK GeneID BIND E2F1 interacts with the TTK chromatin.
E2F1 Protein MT1G GeneID BIND E2F1 interacts with the MT1G promoter.
E2F1 Protein MSH2 GeneID BIND E2F1 interacts with the MSH2 promoter.
E2F1 Protein CHEK1 GeneID BIND E2F1 interacts with the Chk1 promoter.
E2F1 Protein BARD1 GeneID BIND E2F1 interacts with the BARD1 promoter.
E2F1 Protein MLH1 GeneID BIND E2F1 interacts with the MLH1 promoter.
E2F1 Protein RAD54L GeneID BIND E2F1 interacts with the RAD54 promoter.
E2F1 Protein MAD2L1 GeneID BIND E2F1 interacts with the MAD2 promoter.
E2F1 Protein RB1 GeneID BIND Rb interacts with E2F
E2F1 Protein RB1 GeneID BIND E2F1 (RBP3) interacts with pRB.
E2F1 Protein MAD2L1 GeneID BIND E2F interacts with the MAD2 promoter and 5-prime UTR.
E2F1 Protein CCNA2 GeneID BIND E2F interacts with the CycA promoter and 5-prime UTR.
E2F1 Protein NCOA3 GeneID BIND ACTR interacts with E2F1.
E2F1 Protein CCNA1 GeneID BIND cyclin A1 interacts with E2F-1.
E2F1 Protein RB1 GeneID BIND Rb interacts with E2F-1.
StringDB
A B experiments database textmining combined score hadb nhadb
E2F1 CDC34 0 0 108 196 1 1
E2F1 GSK3B 270 0 193 680 1 2
E2F1 ORC4 0 0 82 176 1 1
E2F1 ARRB1 0 0 695 703 1 1
E2F1 CCNG1 0 0 218 423 1 1
E2F1 CDKN2A 676 900 654 988 1 2
E2F1 MRPS18B 0 0 61 282 1 1
E2F1 QSOX2 0 0 0 228 1 1
E2F1 CEBPB 0 650 252 756 1 2
E2F1 SCRIB 0 0 45 154 1 1
E2F1 POC1A 0 0 0 267 1 1
E2F1 PHC3 0 0 144 199 1 1
E2F1 NCAPH 0 0 0 393 1 1
E2F1 NUF2 0 0 60 255 1 1
E2F1 REL 0 0 150 212 1 2
E2F1 HDAC9 0 0 95 184 1 1
E2F1 BRCA2 0 0 266 318 1 1
E2F1 CDCA2 0 0 75 272 1 1
E2F1 HNRNPL 0 0 66 161 1 1
E2F1 ARID3A 270 0 62 301 1 1
E2F1 ERBB3 0 0 150 205 1 1
E2F1 CASP3 0 0 401 414 1 2
E2F1 PTGS2 0 0 158 157 1 2
E2F1 CENPN 0 0 0 165 1 1
E2F1 TNFRSF10B 0 0 150 165 1 2
E2F1 TONSL 0 0 61 159 1 1
E2F1 C17orf64 0 0 0 153 1 1
E2F1 SMARCA1 0 0 66 225 1 1
E2F1 ENSG00000268643 0 0 0 269 1 1
E2F1 CDC20B 0 0 45 211 1 1
E2F1 RAD21 0 0 150 202 1 1
E2F1 HARS 0 0 0 417 1 1
E2F1 HDAC11 0 0 66 163 1 1
E2F1 NEK4 0 0 59 238 1 1
E2F1 SRSF5 0 0 92 165 1 1
E2F1 ASH2L 270 0 0 303 1 1
E2F1 ABCC1 0 0 108 208 1 1
E2F1 BECN1 0 0 184 224 1 2
E2F1 ABCB1 0 0 146 212 1 2
E2F1 THBS1 0 0 146 236 1 1
E2F1 FBXL19 0 0 0 171 1 1
E2F1 CDKN2C 270 0 421 603 1 1
E2F1 CHAF1A 0 0 171 427 1 1
E2F1 AMH 0 0 0 172 1 1
E2F1 NCAPD2 0 0 0 345 1 1
E2F1 CDC25A 0 900 517 967 1 1
E2F1 TMPO 0 0 107 154 1 1
E2F1 RBBP8 0 0 157 194 1 1
E2F1 RXRB 0 0 0 150 1 1
E2F1 CHD9 0 0 0 153 1 1
E2F1 WDR59 0 0 0 232 1 1
E2F1 KDM6B 0 0 184 201 1 1
E2F1 MTFR2 0 0 0 177 1 1
E2F1 FASLG 0 0 171 171 1 1
E2F1 THRB 0 0 95 164 1 1
E2F1 STAT5A 0 0 194 217 1 1
E2F1 MCM6 0 0 322 493 1 1
E2F1 RXRA 0 0 112 289 1 1
E2F1 LIN54 0 900 184 939 1 1
E2F1 FOXK1 0 0 92 173 1 1
E2F1 SFMBT1 0 0 0 152 1 1
E2F1 HOXC8 0 0 57 157 1 1
E2F1 FANCG 0 0 90 214 1 1
E2F1 UEVLD 0 0 0 157 1 1
E2F1 KRAS 0 0 294 369 1 2
E2F1 MPST 0 0 0 292 1 1
E2F1 RARS 0 0 419 419 1 1
E2F1 TBP 675 900 699 989 1 1
E2F1 FN1 0 0 162 161 1 2
E2F1 CDC25B 0 0 260 357 1 1
E2F1 PIGU 0 0 95 190 1 1
E2F1 PKN3 0 0 0 154 1 1
E2F1 ZBTB4 0 0 179 195 1 1
E2F1 CLK2 0 0 0 158 1 1
E2F1 TTK 0 0 170 388 1 1
E2F1 MAP1LC3B 0 0 123 177 1 2
E2F1 UBC 270 0 66 299 1 2
E2F1 TEAD4 0 0 75 263 1 1
E2F1 MCM2 0 0 392 678 1 1
E2F1 TERT 0 0 321 435 1 2
E2F1 HIGD2A 0 0 167 167 1 1
E2F1 AGL 0 0 0 236 1 1
E2F1 TFDP3 0 0 397 700 1 1
E2F1 DCAF15 0 0 0 163 1 1
E2F1 NECAB3 0 0 92 230 1 1
E2F1 CDC45 0 900 324 968 1 1
E2F1 NKX2-1 0 0 105 157 1 1
E2F1 IPO4 0 0 44 172 1 1
E2F1 TTF1 0 0 61 332 1 1
E2F1 MYBL2 192 0 465 842 1 1
E2F1 YAP1 0 0 165 213 1 2
E2F1 OTX2 0 0 46 194 1 1
E2F1 ENSG00000279765 0 0 0 153 1 1
E2F1 BRD8 0 0 70 210 1 1
E2F1 CTPS1 0 0 81 156 1 1
E2F1 NCL 0 0 125 163 1 2
E2F1 ESR1 270 0 406 564 1 2
E2F1 MSH2 0 0 181 249 1 1
E2F1 NSD1 0 0 83 223 1 1
E2F1 RBM38 0 0 139 181 1 1
E2F1 POLD1 0 0 95 374 1 1
E2F1 SENP3 0 0 0 174 1 1
E2F1 PDK4 0 0 171 189 1 1
E2F1 MAZ 0 0 134 214 1 1
E2F1 LMNB1 0 0 151 319 1 1
E2F1 HIST1H4K 0 0 285 307 1 1
E2F1 YARS2 0 0 181 181 1 1
E2F1 PRIM1 0 0 166 394 1 1
E2F1 NGFR 0 900 108 909 1 1
E2F1 E2F3 273 900 836 935 1 1
E2F1 TNFRSF9 0 0 57 155 1 1
E2F1 KAT5 270 0 233 777 1 1
E2F1 MASTL 0 0 107 204 1 1
E2F1 KIT 0 0 181 209 1 2
E2F1 COMMD3-BMI1 0 0 279 297 1 1
E2F1 ZBTB12 0 0 0 169 1 1
E2F1 CCNA1 486 900 685 987 1 1
E2F1 CHURC1-FNTB 0 0 113 249 1 1
E2F1 CHD2 0 0 0 153 1 1
E2F1 LDHA 0 0 103 234 1 2
E2F1 NFATC1 0 0 134 173 1 2
E2F1 E2F5 0 900 738 919 1 1
E2F1 AGO1 0 650 123 700 1 1
E2F1 NTRK3 0 0 42 247 1 1
E2F1 YARS 0 0 140 163 1 1
E2F1 PTTG1 0 0 268 419 1 1
E2F1 DAPK2 0 0 138 156 1 2
E2F1 TAF1L 0 0 139 250 1 1
E2F1 NPM1 0 0 194 218 1 1
E2F1 SRSF3 0 0 104 215 1 1
E2F1 UBE2S 0 0 454 566 1 1
E2F1 SNAI1 0 0 249 248 1 1
E2F1 PA2G4 270 0 0 301 1 1
E2F1 ASPM 0 0 90 292 1 1
E2F1 TRAIP 0 0 112 288 1 1
E2F1 DYRK1B 0 0 45 162 1 1
E2F1 FOSL2 0 0 92 213 1 1
E2F1 MARCKS 0 0 442 442 1 1
E2F1 MDM4 270 0 230 503 1 1
E2F1 ZNF609 0 0 46 437 1 1
E2F1 BRMS1 192 0 74 255 1 1
E2F1 UNG 0 0 85 194 1 1
E2F1 TEAD1 0 0 90 242 1 1
E2F1 MUC6 0 0 0 156 1 1
E2F1 CECR2 0 0 0 209 1 1
E2F1 IGF2 0 0 155 154 1 1
E2F1 DDB2 270 0 705 781 1 1
E2F1 HDAC7 0 0 0 154 1 1
E2F1 RCC1 0 0 218 377 1 1
E2F1 DPYD 0 0 90 159 1 1
E2F1 QSOX1 0 0 0 382 1 1
E2F1 ABCG2 0 0 162 183 1 1
E2F1 PRPF19 0 0 0 154 1 1
E2F1 BCL2L2 0 0 166 196 1 1
E2F1 ATR 270 0 258 479 1 2
E2F1 PAXIP1 0 0 0 209 1 1
E2F1 NTRK1 0 0 95 181 1 1
E2F1 UNC5D 0 0 90 152 1 1
E2F1 IRS1 0 0 161 180 1 2
E2F1 EGR2 0 0 173 189 1 1
E2F1 RPS6KB1 0 900 193 921 1 2
E2F1 NACC2 0 0 328 341 1 1
E2F1 REM1 0 0 0 248 1 1
E2F1 CDK1 463 900 557 983 1 2
E2F1 NCOR1 0 0 170 190 1 1
E2F1 PGR 0 0 218 254 1 1
E2F1 HIST1H4B 0 0 285 307 1 1
E2F1 AHR 270 0 119 433 1 2
E2F1 BARD1 0 0 234 318 1 1
E2F1 DDX5 0 0 162 216 1 1
E2F1 CAT 0 0 122 182 1 2
E2F1 DEK 0 0 150 174 1 1
E2F1 TAL1 0 0 124 176 1 1
E2F1 MRGBP 0 0 0 158 1 1
E2F1 HRK 0 0 405 405 1 1
E2F1 HGF 0 0 135 204 1 2
E2F1 KIF14 0 0 60 169 1 1
E2F1 MCM7 0 0 468 607 1 1
E2F1 POU5F1 0 0 203 252 1 2
E2F1 TOB2 0 0 70 152 1 1
E2F1 DDX46 0 0 0 164 1 1
E2F1 RAD54B 0 0 44 179 1 1
E2F1 KIF22 0 0 0 185 1 1
E2F1 BCL2 0 0 172 202 1 2
E2F1 MYB 0 0 269 490 1 1
E2F1 LIN28A 0 0 142 165 1 1
E2F1 BLM 0 0 54 158 1 2
E2F1 CTLA4 0 0 143 164 1 2
E2F1 CDK3 0 0 344 541 1 1
E2F1 RBBP7 0 0 120 410 1 1
E2F1 TPX2 0 0 150 420 1 1
E2F1 ERCC3 270 0 0 270 1 1
E2F1 LEO1 0 0 0 186 1 1
E2F1 DDX17 0 0 91 150 1 1
E2F1 EAPP 0 0 207 207 1 1
E2F1 SIN3A 0 0 96 171 1 1
E2F1 MEF2C 0 900 96 906 1 1
E2F1 VDR 0 0 123 168 1 2
E2F1 TDG 0 0 53 150 1 1
E2F1 TNF 0 0 218 231 1 2
E2F1 PRC1 0 0 0 224 1 1
E2F1 MAGED2 0 0 70 299 1 1
E2F1 C22orf29 0 0 307 307 1 1
E2F1 NCAPH2 0 0 0 187 1 1
E2F1 ULBP2 0 0 156 177 1 1
E2F1 ANKRD27 0 0 0 171 1 1
E2F1 PCGF2 0 0 148 190 1 1
E2F1 DP2 877 800 252 989 1 1
E2F1 ATF3 0 0 171 228 1 2
E2F1 DRAM1 0 0 155 225 1 2
E2F1 SNCG 0 0 64 157 1 1
E2F1 IFI16 270 0 53 310 1 1
E2F1 SRSF2 0 0 322 356 1 1
E2F1 SMC5 0 0 112 223 1 1
E2F1 CCND2 0 900 458 956 1 1
E2F1 MND1 0 0 53 211 1 1
E2F1 TFAP2A 0 0 181 210 1 1
E2F1 CDC7 0 0 252 314 1 1
E2F1 ERBB2 0 0 395 466 1 2
E2F1 HMGA2 0 0 260 276 1 1
E2F1 FOXF2 0 0 118 191 1 1
E2F1 MTL5 0 0 0 314 1 1
E2F1 FANCD2 0 0 181 260 1 1
E2F1 BBC3 0 900 161 914 1 2
E2F1 CCNE2 0 900 469 966 1 1
E2F1 CDK15 0 0 0 214 1 1
E2F1 TOP1MT 0 0 97 169 1 1
E2F1 SMC4 0 0 112 310 1 1
E2F1 WDHD1 0 0 96 256 1 1
E2F1 CCNG2 0 0 167 386 1 1
E2F1 ID2 0 0 149 164 1 1
E2F1 CDC16 0 0 118 190 1 1
E2F1 OIP5 0 0 60 247 1 1
E2F1 GSK3A 0 0 0 269 1 1
E2F1 SIRT4 0 0 146 164 1 1
E2F1 BIRC5 0 0 358 547 1 2
E2F1 MCM9 0 0 43 264 1 1
E2F1 PPP2R4 0 0 244 243 1 1
E2F1 XIAP 486 0 442 713 1 2
E2F1 ASNS 0 0 357 357 1 1
E2F1 RUNX2 0 0 201 210 1 2
E2F1 BRDT 0 0 94 360 1 1
E2F1 FGFR1 0 0 174 202 1 1
E2F1 HUS1 0 0 146 165 1 1
E2F1 IKBKB 0 0 122 171 1 2
E2F1 KLF4 0 0 211 325 1 2
E2F1 SATB1 0 0 67 269 1 1
E2F1 FOXA1 0 0 123 178 1 1
E2F1 KNTC1 0 0 60 238 1 1
E2F1 ATF4 0 0 304 304 1 2
E2F1 RRM1 0 0 193 352 1 1
E2F1 CD4 0 0 158 157 1 2
E2F1 ATF1 0 0 90 229 1 1
E2F1 AKT1 0 900 467 951 1 2
E2F1 PPARG 0 0 260 289 1 2
E2F1 UBE3A 270 0 276 454 1 1
E2F1 PPP1R13L 0 0 134 156 1 1
E2F1 PHF2 0 0 0 215 1 1
E2F1 MKI67 0 0 193 492 1 2
E2F1 TEAD2 0 0 181 314 1 1
E2F1 FKBPL 0 0 88 190 1 1
E2F1 RB1 998 900 988 999 1 2
E2F1 CTCF 0 0 180 211 1 1
E2F1 GTF2B 0 0 181 357 1 1
E2F1 CDKN1B 0 900 556 956 1 2
E2F1 KIF24 0 0 0 161 1 1
E2F1 CDCA8 0 0 329 573 1 1
E2F1 PPM1D 0 0 210 216 1 1
E2F1 TSC2 0 0 203 214 1 2
E2F1 TRRAP 675 0 167 755 1 1
E2F1 RBX1 0 0 137 190 1 1
E2F1 PHF19 0 0 0 161 1 1
E2F1 CBX2 0 0 60 260 1 1
E2F1 ELK4 0 0 123 258 1 1
E2F1 RASSF1 0 0 155 155 1 1
E2F1 USP1 0 0 134 188 1 1
E2F1 MITF 0 0 146 161 1 2
E2F1 JAK1 189 0 66 238 1 2
E2F1 RRP1B 295 0 0 333 1 1
E2F1 POLD3 0 0 138 164 1 1
E2F1 FBXL6 0 0 0 171 1 1
E2F1 KDM5A 0 0 137 155 1 1
E2F1 BIN1 486 0 44 503 1 1
E2F1 TCHP 0 0 744 744 1 1
E2F1 EIF2AK3 0 0 142 162 1 2
E2F1 TEN1-CDK3 213 0 344 614 1 1
E2F1 UBE2C 0 0 203 469 1 1
E2F1 STAT6 0 0 93 168 1 1
E2F1 RABGEF1 0 0 0 201 1 1
E2F1 CIB1 0 0 370 370 1 1
E2F1 IQGAP3 0 0 57 238 1 1
E2F1 VHL 270 0 95 311 1 2
E2F1 FLT1 0 0 124 155 1 1
E2F1 EED 0 900 134 915 1 1
E2F1 SRC 0 0 272 314 1 2
E2F1 RAET1E 0 0 163 163 1 1
E2F1 RCC2 0 0 0 150 1 1
E2F1 ATAD5 0 0 52 169 1 1
E2F1 CCNI2 0 0 0 293 1 1
E2F1 SMARCC1 0 0 67 174 1 1
E2F1 MCM3 0 0 391 622 1 1
E2F1 MEF2B 0 0 0 156 1 1
E2F1 KDM6A 0 0 167 185 1 1
E2F1 ETV4 0 0 108 265 1 1
E2F1 RHOA 0 0 151 152 1 2
E2F1 PARP1 486 0 435 728 1 2
E2F1 RSL24D1 0 0 308 307 1 1
E2F1 KDM1A 488 0 243 619 1 2
E2F1 ZNF622 0 0 92 352 1 1
E2F1 GTF2H1 486 0 456 708 1 2
E2F1 KLRK1 0 0 194 194 1 1
E2F1 PIWIL1 0 0 123 175 1 1
E2F1 SETMAR 0 0 0 197 1 1
E2F1 GABPB1 270 0 93 330 1 1
E2F1 FEN1 0 0 171 340 1 1
E2F1 EPC1 0 0 61 164 1 1
E2F1 ESR2 0 0 161 174 1 1
E2F1 SIRT7 0 0 131 151 1 2
E2F1 SCML4 0 0 0 152 1 1
E2F1 ZEB1 0 0 252 262 1 2
E2F1 CEBPE 270 0 53 331 1 1
E2F1 FOSL1 0 0 113 204 1 1
E2F1 SETDB1 0 0 72 170 1 1
E2F1 PAX8 270 0 63 331 1 1
E2F1 PTGDR 0 900 123 908 1 1
E2F1 NPAT 0 0 203 207 1 1
E2F1 HPGDS 0 0 241 241 1 1
E2F1 FBXW7 0 0 282 282 1 2
E2F1 HTRA2 0 0 51 214 1 1
E2F1 SETD1A 270 0 97 416 1 1
E2F1 CEBPA 0 600 253 740 1 1
E2F1 WRN 0 0 142 201 1 1
E2F1 SUV39H1 0 900 245 940 1 1
E2F1 ACTB 0 0 404 427 1 2
E2F1 INS 0 0 282 282 1 2
E2F1 CIT 0 0 0 191 1 1
E2F1 MXD3 0 0 49 282 1 1
E2F1 STUB1 0 0 211 265 1 2
E2F1 DNMT1 270 900 345 952 1 2
E2F1 GTSE1 0 0 55 235 1 1
E2F1 ANLN 0 0 67 220 1 1
E2F1 MCM5 0 0 342 576 1 1
E2F1 ANGPT1 0 0 0 214 1 1
E2F1 PROM1 0 0 143 175 1 2
E2F1 SIRT3 0 0 154 172 1 2
E2F1 GLI3 0 0 135 232 1 1
E2F1 HIST1H4J 0 0 285 307 1 1
E2F1 KHSRP 0 0 96 171 1 1
E2F1 DNAJC9 0 0 0 171 1 1
E2F1 CHEK1 0 0 467 603 1 2
E2F1 MTBP 0 0 134 224 1 1
E2F1 CDC20 486 0 341 832 1 1
E2F1 SRF 0 0 123 159 1 1
E2F1 RFC2 0 0 67 187 1 1
E2F1 ZFP36 0 0 113 176 1 1
E2F1 BRD3 0 0 123 394 1 1
E2F1 NR2F2 0 0 97 216 1 1
E2F1 TSC1 0 0 0 156 1 2
E2F1 HNRNPA1 0 0 125 157 1 1
E2F1 KIF11 0 0 144 312 1 1
E2F1 WDR5 0 0 104 221 1 1
E2F1 BCL2L11 0 0 404 404 1 2
E2F1 SAC3D1 0 0 0 158 1 1
E2F1 DCAF10 0 0 0 212 1 1
E2F1 NME4 0 0 56 183 1 1
E2F1 SNAPC4 0 0 0 273 1 1
E2F1 SMYD3 0 0 123 175 1 1
E2F1 SHH 0 0 208 227 1 2
E2F1 CSNK1A1 270 0 92 334 1 1
E2F1 ATAD2 270 0 450 662 1 1
E2F1 CABLES1 0 0 59 150 1 1
E2F1 MED12 0 0 91 156 1 1
E2F1 DNA2 0 0 54 160 1 1
E2F1 RPA2 0 0 134 159 1 1
E2F1 BIK 0 0 128 151 1 2
E2F1 SAE1 0 0 45 168 1 1
E2F1 CD8A 0 0 157 156 1 1
E2F1 MNAT1 213 0 0 213 1 1
E2F1 POLQ 0 0 60 187 1 1
E2F1 SHCBP1 0 0 52 200 1 1
E2F1 FANCA 0 0 143 322 1 1
E2F1 ARID1B 0 0 0 181 1 1
E2F1 FZR1 486 0 263 689 1 1
E2F1 ZBTB17 0 0 306 319 1 1
E2F1 MMP2 0 0 213 213 1 2
E2F1 UHRF2 270 0 53 309 1 1
E2F1 TFAM 0 0 150 223 1 2
E2F1 ETV1 0 0 91 157 1 1
E2F1 SKP2 874 0 623 956 1 2
E2F1 BTG3 270 0 137 422 1 1
E2F1 AURKB 0 0 308 509 1 1
E2F1 ANAPC1 0 0 181 243 1 1
E2F1 RUVBL1 0 0 94 150 1 1
E2F1 HIST1H2AI 0 0 0 166 1 1
E2F1 ADIPOQ 0 0 74 171 1 2
E2F1 E4F1 0 0 0 150 1 1
E2F1 IPO11 0 0 50 231 1 1
E2F1 HIST2H3PS2 0 0 418 439 1 1
E2F1 FOXI1 0 0 0 159 1 1
E2F1 FAM72A 0 0 0 150 1 1
E2F1 TNS1 0 0 166 213 1 1
E2F1 SMARCB1 0 0 113 207 1 1
E2F1 H2AFZ 0 0 86 232 1 1
E2F1 NR3C1 0 0 174 258 1 1
E2F1 RPS6KB2 0 0 419 460 1 2
E2F1 CTGF 0 0 138 168 1 1
E2F1 SCMH1 0 0 0 152 1 1
E2F1 CDKN1C 270 900 408 956 1 1
E2F1 CEP250 0 0 270 297 1 1
E2F1 TRIP13 0 0 0 244 1 1
E2F1 RAD17 0 0 145 241 1 1
E2F1 TRIB1 0 0 294 311 1 1
E2F1 BPTF 0 0 72 327 1 1
E2F1 MYCL 0 0 233 232 1 1
E2F1 CEBPD 270 0 103 366 1 1
E2F1 LIN52 0 900 144 935 1 1
E2F1 CHEK2 213 0 622 710 1 1
E2F1 PLK2 0 0 66 162 1 1
E2F1 CASP9 0 0 251 258 1 2
E2F1 NANOG 0 0 210 264 1 2
E2F1 ETS1 0 900 268 927 1 1
E2F1 FASN 0 0 134 244 1 2
E2F1 SETD7 675 0 144 721 1 1
E2F1 CACNB3 0 0 56 157 1 1
E2F1 SMARCA5 0 0 96 250 1 1
E2F1 HCFC1 487 0 245 658 1 1
E2F1 RIBC2 0 0 122 173 1 1
E2F1 TICRR 0 0 143 391 1 1
E2F1 CKAP2L 0 0 64 177 1 1
E2F1 CASP8 0 0 243 252 1 2
E2F1 MCM4 0 0 299 548 1 1
E2F1 PIWIL4 0 0 123 175 1 1
E2F1 KIAA0101 0 0 70 211 1 1
E2F1 CDK19 0 0 57 174 1 1
E2F1 KAT2A 675 0 468 875 1 1
E2F1 TNFAIP8L2 0 0 45 356 1 1
E2F1 ENSG00000269905 0 0 252 616 1 1
E2F1 FNDC3A 0 0 487 487 1 1
E2F1 LGALS4 0 0 204 204 1 1
E2F1 PIK3R5 0 0 0 422 1 1
E2F1 CUL5 0 0 95 164 1 1
E2F1 SCML1 0 0 0 152 1 1
E2F1 SUZ12 0 900 229 933 1 1
E2F1 CCNB3 0 0 140 366 1 1
E2F1 TEAD3 192 0 0 311 1 1
E2F1 KIF20A 0 0 167 413 1 1
E2F1 CUX1 0 0 150 170 1 1
E2F1 H2AFX 0 0 255 429 1 1
E2F1 LRFN4 0 0 0 153 1 1
E2F1 CDK6 0 900 726 976 1 2
E2F1 GLI2 0 0 96 196 1 2
E2F1 HIST1H4E 0 0 285 307 1 1
E2F1 TMEM201 0 0 0 153 1 1
E2F1 NDC1 0 0 0 158 1 1
E2F1 ZEB2 0 0 195 195 1 1
E2F1 BOP1 0 0 0 203 1 1
E2F1 HK2 0 0 108 226 1 2
E2F1 KIF15 0 0 81 287 1 1
E2F1 LMNA 0 0 180 208 1 2
E2F1 EXO1 0 0 142 433 1 1
E2F1 DDIT3 0 0 134 196 1 2
E2F1 DDX54 0 0 0 202 1 1
E2F1 CKS1B 0 0 211 413 1 1
E2F1 GART 0 0 93 208 1 1
E2F1 HIST1H4I 0 0 285 307 1 1
E2F1 CDK4 0 900 832 986 1 2
E2F1 METAP2 0 0 307 307 1 1
E2F1 EME1 0 0 0 188 1 1
E2F1 UCHL5 270 0 0 270 1 1
E2F1 RNASEH2A 0 0 67 181 1 1
E2F1 GATA3 0 0 120 193 1 1
E2F1 NF2 0 0 123 155 1 1
E2F1 NASP 0 0 101 165 1 1
E2F1 XRCC6 0 0 400 414 1 1
E2F1 EZH2 279 900 552 970 1 2
E2F1 UBE2T 0 0 43 238 1 1
E2F1 STAT3 0 650 358 779 1 2
E2F1 PPP1R12C 0 0 0 465 1 1
E2F1 HTRA1 0 0 54 164 1 1
E2F1 TGFA 0 0 98 150 1 1
E2F1 CDK14 0 0 0 214 1 1
E2F1 AGO2 0 0 181 229 1 2
E2F1 KDM7A 0 0 64 166 1 1
E2F1 KIF18B 0 0 81 250 1 1
E2F1 SETD8 0 0 113 181 1 1
E2F1 RNF126 270 0 52 321 1 1
E2F1 BAZ2A 0 0 0 192 1 1
E2F1 CTBP2 0 0 122 193 1 1
E2F1 KIF4A 0 0 71 338 1 1
E2F1 SRSF1 0 0 95 177 1 1
E2F1 RUVBL2 0 0 445 499 1 1
E2F1 ZBED1 0 0 0 179 1 1
E2F1 NDNL2 270 900 687 983 1 1
E2F1 PIK3CA 0 0 272 313 1 2
E2F1 KIF18A 0 0 49 159 1 1
E2F1 GSC 0 900 0 902 1 1
E2F1 APEX1 0 0 96 152 1 1
E2F1 IL1R1 189 0 0 189 1 1
E2F1 MYC 0 900 697 971 1 2
E2F1 CENPU 0 0 54 211 1 1
E2F1 ENSG00000279576 0 0 203 203 1 1
E2F1 H1F0 0 0 263 313 1 1
E2F1 KIF2C 0 0 113 452 1 1
E2F1 USF1 0 0 181 217 1 1
E2F1 SDHC 0 0 401 400 1 1
E2F1 IGF1R 0 0 235 262 1 2
E2F1 AKT2 0 0 138 217 1 2
E2F1 CDK20 0 0 0 160 1 1
E2F1 EHMT2 0 900 143 927 1 2
E2F1 NFE2L2 0 0 141 172 1 2
E2F1 ODC1 0 0 262 289 1 1
E2F1 CARD10 0 0 52 177 1 1
E2F1 EID1 0 0 229 228 1 1
E2F1 MAP2K1 0 0 171 192 1 1
E2F1 TADA2A 0 0 48 252 1 1
E2F1 SCML2 0 0 67 199 1 1
E2F1 BRD9 0 0 0 156 1 1
E2F1 HDAC5 0 0 73 168 1 1
E2F1 KIFC1 0 0 117 402 1 1
E2F1 MYCN 0 0 402 415 1 1
E2F1 SMAD4 0 0 218 237 1 2
E2F1 HIST1H4L 0 0 285 307 1 1
E2F1 HDAC3 0 900 113 920 1 2
E2F1 SPAG5 0 0 0 333 1 1
E2F1 ANAPC11 270 0 60 305 1 1
E2F1 AGO4 0 650 0 670 1 1
E2F1 FHL2 192 0 107 264 1 1
E2F1 FOXM1 0 0 457 647 1 1
E2F1 WHSC1 0 0 72 261 1 1
E2F1 CCNB1 0 900 502 968 1 1
E2F1 ANXA5 0 0 294 307 1 2
E2F1 SIAH1 0 0 151 150 1 1
E2F1 PLK1 0 0 401 557 1 2
E2F1 MAGEA8 0 0 0 177 1 1
E2F1 KCNJ11 0 0 139 160 1 1
E2F1 EP400 0 0 82 212 1 1
E2F1 POLE 0 0 0 220 1 1
E2F1 NDN 486 900 872 994 1 1
E2F1 DCLRE1B 0 0 0 180 1 1
E2F1 NSF 0 0 0 165 1 2
E2F1 BIRC2 675 0 447 820 1 1
E2F1 SLC25A10 0 0 0 200 1 1
E2F1 BCL9L 0 0 296 310 1 1
E2F1 CHD7 0 0 0 153 1 1
E2F1 ZSCAN21 0 0 74 157 1 1
E2F1 SMAD2 0 0 161 174 1 2
E2F1 NF1 0 0 155 264 1 1
E2F1 PAQR4 0 0 0 245 1 1
E2F1 ELF1 0 900 75 905 1 1
E2F1 ATRX 0 0 135 219 1 1
E2F1 WDR73 0 0 0 189 1 1
E2F1 C16orf59 0 0 0 181 1 1
E2F1 DHRS4 0 0 0 194 1 1
E2F1 BCL2L1 0 0 324 362 1 2
E2F1 ANAPC5 486 0 90 538 1 1
E2F1 MCPH1 675 0 697 904 1 1
E2F1 PELP1 0 0 134 165 1 2
E2F1 XPA 0 0 142 162 1 1
E2F1 PSRC1 0 0 0 163 1 1
E2F1 DNMT3A 0 0 217 267 1 2
E2F1 UHRF1 0 0 150 338 1 1
E2F1 L3MBTL3 486 0 0 552 1 1
E2F1 SAPCD2 0 0 46 215 1 1
E2F1 HMGB2 0 0 74 210 1 1
E2F1 DNMT3B 0 0 184 338 1 1
E2F1 CDK2 754 900 767 996 1 2
E2F1 H2AFV 0 0 0 163 1 1
E2F1 DDX18 0 0 306 351 1 1
E2F1 ELK1 0 0 113 194 1 1
E2F1 XPO1 0 0 142 181 1 1
E2F1 CDCA4 0 0 536 600 1 1
E2F1 SP1 766 600 730 974 1 2
E2F1 KREMEN2 0 0 0 177 1 1
E2F1 RAD54L 0 0 103 431 1 1
E2F1 SIRT5 0 0 181 198 1 1
E2F1 HIF1A 0 0 625 634 1 2
E2F1 CNTD2 0 0 0 293 1 1
E2F1 GABPA 0 0 144 210 1 1
E2F1 ID1 0 0 223 258 1 1
E2F1 CDCA5 0 0 95 582 1 1
E2F1 LATS2 0 0 240 247 1 1
E2F1 NFYB 0 0 122 180 1 1
E2F1 IL6 0 0 211 218 1 2
E2F1 WDR34 0 0 0 177 1 1
E2F1 MYSM1 0 0 0 176 1 1
E2F1 PPP1R12A 0 0 42 203 1 1
E2F1 SERTAD1 0 0 486 485 1 1
E2F1 MYOG 0 0 161 167 1 1
E2F1 CENPM 0 0 0 211 1 1
E2F1 CCNF 270 0 236 618 1 1
E2F1 TBX2 0 0 88 165 1 1
E2F1 E2F6 213 900 681 927 1 1
E2F1 ATRIP 0 0 165 214 1 1
E2F1 FOXO6 0 0 124 169 1 1
E2F1 BRD2 487 0 205 709 1 1
E2F1 CBX3 0 900 143 915 1 1
E2F1 CCNC 0 0 235 253 1 1
E2F1 NOTCH1 0 0 343 357 1 2
E2F1 PRMT1 0 0 140 191 1 1
E2F1 CD40LG 0 0 47 209 1 1
E2F1 TRAF4 0 0 67 467 1 1
E2F1 POTEF 0 0 134 168 1 1
E2F1 KAT7 0 0 75 202 1 1
E2F1 CHD6 0 0 0 153 1 1
E2F1 SORT1 0 900 0 900 1 1
E2F1 SMARCAD1 0 0 0 165 1 1
E2F1 XRCC5 0 0 242 241 1 1
E2F1 PBRM1 0 0 55 222 1 1
E2F1 CSTF2 0 0 134 188 1 1
E2F1 SFN 0 0 167 187 1 2
E2F1 ERCC1 0 0 162 161 1 1
E2F1 DTL 0 0 165 626 1 1
E2F1 HIST2H4A 0 0 285 307 1 1
E2F1 CUL3 0 0 145 239 1 2
E2F1 CHUK 0 0 155 184 1 1
E2F1 KLF2 0 0 155 236 1 1
E2F1 RBL2 486 900 628 988 1 1
E2F1 DHFR 0 900 459 953 1 1
E2F1 FBXO5 0 900 293 932 1 1
E2F1 RACGAP1 0 0 75 260 1 1
E2F1 CHD8 0 0 0 153 1 1
E2F1 HMGB3 0 0 134 187 1 1
E2F1 RRM2 0 900 393 958 1 1
E2F1 HDAC1 753 900 576 992 1 2
E2F1 POLA2 0 0 139 243 1 1
E2F1 KIAA1524 0 0 413 497 1 1
E2F1 DTYMK 0 0 90 236 1 1
E2F1 KAT8 0 0 90 215 1 1
E2F1 GAPVD1 0 0 0 152 1 1
E2F1 CDC27 270 0 109 373 1 1
E2F1 NCAPG 0 0 0 362 1 1
E2F1 PRMT2 270 0 96 327 1 1
E2F1 HEATR6 0 0 193 229 1 1
E2F1 USP11 0 0 59 172 1 2
E2F1 ISYNA1 0 0 358 377 1 1
E2F1 B4GALT2 0 0 0 179 1 1
E2F1 HELLS 0 0 261 422 1 1
E2F1 TIMELESS 0 0 67 265 1 1
E2F1 CD28 0 0 90 177 1 1
E2F1 MYT1 0 0 71 233 1 1
E2F1 ADCY10 0 0 139 159 1 1
E2F1 WEE1 0 0 391 444 1 1
E2F1 PHIP 0 0 0 226 1 1
E2F1 LRRK2 0 0 82 220 1 2
E2F1 PHB 753 0 140 786 1 1
E2F1 MET 0 0 216 243 1 2
E2F1 CDKN2B 0 0 466 482 1 1
E2F1 PMAIP1 0 900 292 930 1 2
E2F1 PARP2 0 0 122 170 1 1
E2F1 RFC5 0 0 123 224 1 1
E2F1 CDT1 0 900 391 964 1 1
E2F1 TWIST1 0 0 184 183 1 1
E2F1 CBX7 0 0 140 175 1 1
E2F1 S100A8 0 0 44 208 1 2
E2F1 FOS 0 0 306 361 1 2
E2F1 PTPN11 270 0 66 304 1 1
E2F1 BTRC 270 0 270 486 1 1
E2F1 NRAS 0 0 193 211 1 1
E2F1 CDK9 0 0 246 245 1 1
E2F1 FOXO1 0 0 323 396 1 2
E2F1 AKT3 0 0 81 154 1 2
E2F1 DDX11 0 0 81 208 1 1
E2F1 UNC5B 0 0 67 152 1 1
E2F1 RARA 270 0 112 334 1 2
E2F1 PSMD14 486 0 95 541 1 1
E2F1 KDM5B 0 0 151 169 1 1
E2F1 DHRS4L2 0 0 0 194 1 1
E2F1 HNRNPK 0 0 143 182 1 1
E2F1 NBN 486 0 245 606 1 1
E2F1 KLF16 0 0 67 174 1 1
E2F1 STMN1 0 0 165 205 1 1
E2F1 LIG1 0 0 0 303 1 1
E2F1 SOD3 0 0 262 262 1 1
E2F1 NEK2 0 0 187 292 1 1
E2F1 ARID1A 0 0 116 221 1 1
E2F1 CHD3 0 0 48 155 1 1
E2F1 ENSG00000255819 0 0 194 194 1 1
E2F1 GLI1 0 0 141 363 1 2
E2F1 DYRK1A 0 0 144 269 1 1
E2F1 RANBP1 0 0 66 185 1 1
E2F1 TGFBR1 0 0 97 176 1 1
E2F1 SP3 270 0 193 412 1 1
E2F1 TP63 0 0 150 243 1 2
E2F1 HIPK2 0 0 134 226 1 2
E2F1 PCNA 0 900 261 945 1 2
E2F1 WDR18 0 0 0 174 1 1
E2F1 POLE3 0 0 87 252 1 1
E2F1 PPP1CA 0 0 92 156 1 1
E2F1 RBBP4 270 900 259 953 1 1
E2F1 ORC2 0 0 43 291 1 1
E2F1 EHMT1 0 900 45 916 1 1
E2F1 COPS5 0 0 164 303 1 1
E2F1 GATA2 0 0 154 225 1 1
E2F1 EIF5A 0 0 0 158 1 2
E2F1 EYA4 0 0 0 159 1 1
E2F1 MAP3K5 0 0 181 181 1 1
E2F1 MCL1 0 0 323 347 1 2
E2F1 SMARCA4 0 0 361 505 1 1
E2F1 SIRT1 675 0 681 894 1 2
E2F1 SPI1 0 900 171 920 1 1
E2F1 TP53BP1 270 0 242 454 1 1
E2F1 ERCC6L 0 0 0 237 1 1
E2F1 SREBF1 0 0 144 169 1 1
E2F1 HIST1H4A 0 0 285 307 1 1
E2F1 TP53BP2 0 0 166 172 1 2
E2F1 MAPK14 0 0 90 198 1 2
E2F1 LMNB2 0 0 132 296 1 1
E2F1 TIMP3 0 0 160 159 1 1
E2F1 MGEA5 0 0 306 306 1 1
E2F1 NFKBIA 0 0 251 274 1 2
E2F1 WT1 0 0 150 405 1 1
E2F1 RDM1 0 0 0 152 1 1
E2F1 ATAD2B 0 0 74 172 1 1
E2F1 UBN1 273 0 0 289 1 1
E2F1 SRCAP 0 0 0 171 1 1
E2F1 MYOD1 0 0 306 327 1 1
E2F1 CYFIP2 0 0 107 159 1 1
E2F1 GINS2 0 0 0 232 1 1
E2F1 PTEN 0 0 490 525 1 2
E2F1 NCOA6 270 0 74 391 1 1
E2F1 VEGFA 0 0 322 321 1 2
E2F1 NFIA 0 0 156 167 1 1
E2F1 GMNN 0 0 294 392 1 1
E2F1 RBPJ 0 0 142 267 1 1
E2F1 RMI2 0 0 54 265 1 1
E2F1 CPT1C 0 0 0 190 1 1
E2F1 CDK7 864 0 286 911 1 1
E2F1 CHD4 0 0 90 209 1 1
E2F1 ORC5 0 0 53 304 1 1
E2F1 ACTG1 0 0 141 187 1 1
E2F1 RECQL4 0 0 107 461 1 1
E2F1 BTG2 0 0 212 282 1 1
E2F1 MCM8 0 0 77 216 1 1
E2F1 TGFBR2 0 0 181 210 1 1
E2F1 BAZ2B 0 0 0 192 1 1
E2F1 ENSG00000267261 0 0 0 212 1 1
E2F1 LIN9 0 900 161 943 1 1
E2F1 RET 0 0 134 163 1 1
E2F1 POLE2 0 0 167 306 1 1
E2F1 ATM 270 900 504 964 1 2
E2F1 TUBGCP2 0 0 61 175 1 1
E2F1 FLI1 0 0 91 167 1 1
E2F1 ANAPC7 270 0 53 284 1 1
E2F1 CCND1 0 900 661 973 1 2
E2F1 TACC3 0 0 74 272 1 1
E2F1 RRM2B 0 0 168 267 1 1
E2F1 GRAMD4 0 0 218 218 1 1
E2F1 VANGL1 0 0 0 184 1 1
E2F1 WDR77 0 0 93 168 1 1
E2F1 UBE2I 0 0 81 150 1 1
E2F1 GINS3 0 0 74 160 1 1
E2F1 MGA 192 900 59 922 1 1
E2F1 L3MBTL2 0 900 44 911 1 1
E2F1 TOPBP1 874 900 452 996 1 1
E2F1 CCDC86 0 0 91 164 1 1
E2F1 DMTF1 0 0 66 264 1 1
E2F1 PRRX2 0 0 0 160 1 1
E2F1 KAT2B 753 900 407 987 1 1
E2F1 MCMBP 0 0 66 198 1 1
E2F1 YWHAQ 270 0 48 275 1 1
E2F1 EIF4E 0 0 138 177 1 2
E2F1 HIST2H2BE 0 0 166 165 1 1
E2F1 ETV6 0 0 0 188 1 1
E2F1 PRKDC 0 0 210 300 1 2
E2F1 ARID4A 0 0 125 162 1 1
E2F1 NDC80 0 0 101 239 1 1
E2F1 CLK1 0 0 57 209 1 1
E2F1 RUNX1 0 0 90 182 1 2
E2F1 FANCI 0 0 66 222 1 1
E2F1 CCNE1 270 900 506 980 1 1
E2F1 MCM10 0 0 261 420 1 1
E2F1 TNRC6A 0 650 54 657 1 1
E2F1 KIF23 0 0 113 294 1 1
E2F1 HINFP 0 0 306 324 1 1
E2F1 AHCY 0 0 81 179 1 1
E2F1 MDK 0 0 0 208 1 1
E2F1 HIST2H4B 0 0 285 307 1 1
E2F1 E2F8 270 900 499 951 1 1
E2F1 CROCC 0 0 294 294 1 1
E2F1 SFMBT2 0 0 0 152 1 1
E2F1 CENPH 0 0 0 161 1 1
E2F1 DDX3X 0 0 63 321 1 1
E2F1 RP1 0 0 0 167 1 1
E2F1 NRIP1 500 0 210 588 1 1
E2F1 BAHD1 0 0 134 213 1 1
E2F1 SHPRH 0 0 46 204 1 1
E2F1 CD44 0 0 143 182 1 2
E2F1 SLC1A5 0 0 94 185 1 1
E2F1 CASP2 0 0 171 196 1 1
E2F1 LMCD1 0 0 428 428 1 1
E2F1 TIPIN 0 0 109 191 1 1
E2F1 EYA1 0 0 82 275 1 1
E2F1 YBX1 0 0 163 204 1 1
E2F1 RHAG 0 0 262 262 1 1
E2F1 SLC19A1 0 0 0 159 1 1
E2F1 IGF1 192 0 246 381 1 2
E2F1 ANAPC2 0 0 122 195 1 1
E2F1 MAPK1 0 0 161 191 1 2
E2F1 SUV39H2 0 0 0 217 1 1
E2F1 CCND3 0 900 459 956 1 1
E2F1 DCAF5 270 0 0 338 1 1
E2F1 PKM 0 0 134 201 1 1
E2F1 ESRRB 0 0 52 161 1 1
E2F1 RPS19BP1 0 0 155 198 1 1
E2F1 GADD45A 0 0 305 309 1 1
E2F1 ABCB10 0 0 0 152 1 1
E2F1 FGF2 0 0 217 217 1 2
E2F1 RELB 0 0 141 174 1 2
E2F1 FOXK2 0 0 143 291 1 1
E2F1 CDK17 0 0 0 214 1 1
E2F1 TYMP 0 0 66 317 1 1
E2F1 GINS4 0 0 105 174 1 1
E2F1 HIST1H4H 0 0 285 307 1 1
E2F1 CUL4B 76 0 103 223 1 1
E2F1 PTCH1 0 0 134 188 1 1
E2F1 NGF 0 900 134 909 1 2
E2F1 ACTL10 0 0 125 412 1 1
E2F1 NCAPD3 0 0 81 270 1 1
E2F1 AGO3 0 650 0 670 1 1
E2F1 NEIL3 0 0 0 179 1 1
E2F1 SMC6 0 0 73 211 1 1
E2F1 CHTF18 0 0 0 294 1 1
E2F1 DDX56 0 0 0 157 1 1
E2F1 EP400NL 0 0 0 177 1 1
E2F1 FOXO4 0 0 260 276 1 1
E2F1 HNRNPUL2 0 0 113 173 1 1
E2F1 EIF4EBP1 0 0 138 189 1 2
E2F1 POLA1 0 900 103 922 1 1
E2F1 TYMS 0 900 408 952 1 1
E2F1 INO80 0 0 0 222 1 1
E2F1 HMGA1 0 0 112 267 1 1
E2F1 PHGDH 0 0 181 231 1 1
E2F1 SSRP1 0 0 48 194 1 1
E2F1 BCL6 0 0 140 188 1 1
E2F1 E2F4 270 900 801 944 1 1
E2F1 DROSHA 0 0 224 263 1 1
E2F1 MZF1 0 0 150 166 1 1
E2F1 CDK8 270 0 500 667 1 1
E2F1 NTRK2 0 0 48 173 1 1
E2F1 RBAK 0 0 160 195 1 1
E2F1 CDK18 0 0 63 265 1 1
E2F1 SUMO1 0 0 92 153 1 1
E2F1 MXD1 0 0 124 153 1 1
E2F1 CA9 0 0 93 207 1 1
E2F1 MBTPS1 189 0 0 210 1 1
E2F1 SPIB 192 0 61 208 1 1
E2F1 CTDP1 213 0 0 253 1 1
E2F1 HIST1H4C 0 0 285 333 1 1
E2F1 NPDC1 462 0 838 909 1 1
E2F1 RNF144A 192 0 0 210 1 1
E2F1 ZWINT 0 0 0 321 1 1
E2F1 USP7 0 0 150 280 1 1
E2F1 CLK4 0 0 0 157 1 1
E2F1 DDX20 0 0 66 179 1 1
E2F1 ISX 0 0 108 158 1 1
E2F1 DDB1 270 0 213 442 1 1
E2F1 STAT5B 0 0 181 204 1 1
E2F1 GADD45G 0 0 95 259 1 1
E2F1 TGFB1 0 0 126 276 1 2
E2F1 HMMR 0 0 89 277 1 1
E2F1 NKX3-1 0 0 150 204 1 1
E2F1 RPL11 0 0 103 158 1 1
E2F1 YY1 0 0 333 381 1 1
E2F1 SKP1 0 0 261 261 1 2
E2F1 PRMT5 270 0 210 428 1 1
E2F1 HIAT1 0 0 0 177 1 1
E2F1 RNF2 0 900 116 910 1 1
E2F1 GLCE 0 0 242 241 1 1
E2F1 KDR 0 0 127 179 1 2
E2F1 DMP1 0 0 0 167 1 1
E2F1 TLX3 0 0 45 191 1 1
E2F1 HIST1H4D 0 0 285 307 1 1
E2F1 PRIM2 0 0 67 221 1 1
E2F1 PRDM2 270 0 68 295 1 1
E2F1 HNF4A 0 0 235 254 1 1
E2F1 EWSR1 0 0 150 171 1 1
E2F1 CORO1A 0 0 0 170 1 1
E2F1 CDKN3 0 0 458 533 1 1
E2F1 TRIM28 486 900 453 973 1 2
E2F1 BIRC6 0 0 61 171 1 1
E2F1 ORC6 0 0 195 322 1 1
E2F1 HARS2 0 0 0 417 1 1
E2F1 DKC1 0 0 123 208 1 1
E2F1 PKMYT1 0 0 183 635 1 1
E2F1 CCNO 0 0 0 318 1 1
E2F1 SIN3B 0 0 112 155 1 1
E2F1 SP2 270 0 0 313 1 1
E2F1 ACIN1 0 0 134 193 1 1
E2F1 FOXO3 0 0 540 652 1 2
E2F1 SLC2A4 0 0 70 231 1 1
E2F1 NEK1 0 0 0 158 1 1
E2F1 CDKN1A 273 900 609 974 1 2
E2F1 ECT2 0 0 146 266 1 1
E2F1 BID 0 0 124 205 1 2
E2F1 AR 270 0 348 563 1 2
E2F1 CDCA7 0 0 235 386 1 1
E2F1 RAD51AP1 0 0 57 227 1 1
E2F1 PTTG2 0 0 113 183 1 1
E2F1 AURKA 0 0 265 454 1 2
E2F1 RPL24 0 0 307 307 1 1
E2F1 BAX 0 0 141 196 1 2
E2F1 PCGF6 0 900 0 902 1 1
E2F1 TST 0 0 0 414 1 1
E2F1 NELFE 0 0 0 229 1 1
E2F1 BCL2L12 0 0 76 193 1 1
E2F1 CCNB2 0 0 322 594 1 1
E2F1 ZNF711 0 0 0 263 1 1
E2F1 DEPDC1B 0 0 83 208 1 1
E2F1 DDX4 0 0 49 311 1 1
E2F1 HSP90AA1 0 0 225 236 1 2
E2F1 CTBP1 0 0 183 249 1 1
E2F1 E2F7 270 900 502 953 1 1
E2F1 HIST2H2AA3 0 0 181 222 1 1
E2F1 HDAC4 0 0 117 204 1 2
E2F1 SOX2 0 0 258 292 1 2
E2F1 ATF2 0 0 95 157 1 1
E2F1 TP73 486 0 177 700 1 2
E2F1 RFC4 0 0 261 359 1 1
E2F1 ASS1 0 0 0 190 1 1
E2F1 WHSC1L1 0 0 0 188 1 1
E2F1 NCAPG2 0 0 46 291 1 1
E2F1 HIST2H2AA 0 0 181 222 1 1
E2F1 ARHGDIA 0 0 81 157 1 1
E2F1 MAPK3 0 0 281 298 1 2
E2F1 GTF2I 0 0 454 454 1 1
E2F1 MMP9 0 0 218 242 1 2
E2F1 CUL4A 0 0 194 276 1 1
E2F1 JUNB 0 0 122 182 1 1
E2F1 NIPBL 0 0 66 169 1 1
E2F1 BNIP3 0 0 181 181 1 2
E2F1 TFDP1 982 900 451 999 1 1
E2F1 MICB 0 0 162 161 1 1
E2F1 CCNA2 875 900 858 998 1 1
E2F1 EIF2AK1 0 0 0 265 1 1
E2F1 NCOA2 0 0 103 180 1 1
E2F1 TK1 270 900 370 976 1 1
E2F1 DNTT 0 0 131 173 1 1
E2F1 GAS2L1 0 0 67 277 1 1
E2F1 HMG20B 0 0 70 154 1 1
E2F1 HIC1 0 0 193 223 1 1
E2F1 COL18A1 0 0 71 151 1 1
E2F1 ERBB4 0 0 135 187 1 1
E2F1 CYP19A1 0 0 193 193 1 2
E2F1 SKA3 0 0 0 267 1 1
E2F1 CDCA3 0 0 171 338 1 1
E2F1 TAF1 0 0 133 245 1 1
E2F1 DAPK1 0 0 113 192 1 2
E2F1 FAM72C 0 0 0 170 1 1
E2F1 GAS2L2 0 0 0 177 1 1
E2F1 JUN 0 0 390 403 1 2
E2F1 ASF1A 273 0 161 407 1 1
E2F1 ASF1B 0 0 190 475 1 1
E2F1 ARHGAP11A 0 0 92 217 1 1
E2F1 DCAF4 44 0 173 175 1 1
E2F1 CEP55 0 0 59 259 1 1
E2F1 MAX 0 900 243 933 1 2
E2F1 ZBED4 0 0 89 269 1 1
E2F1 ATAD3A 0 0 0 208 1 1
E2F1 CENPE 0 0 150 257 1 1
E2F1 KPNA2 0 0 167 285 1 1
E2F1 CDC25C 0 0 325 491 1 2
E2F1 TBL1X 0 0 138 179 1 1
E2F1 ELOVL6 0 0 81 240 1 1
E2F1 SMC1A 0 0 108 220 1 1
E2F1 SMC3 0 0 75 207 1 1
E2F1 BMI1 0 0 284 302 1 1
E2F1 ARNT 0 0 141 180 1 2
E2F1 SMAD1 0 0 71 151 1 2
E2F1 RING1 389 900 102 943 1 1
E2F1 BTG1 0 0 74 156 1 1
E2F1 LIN37 0 900 135 924 1 1
E2F1 NCOA3 676 0 263 753 1 1
E2F1 COMMD5 0 0 75 162 1 1
E2F1 SERTAD2 213 0 138 292 1 1
E2F1 MAPK8 0 0 149 150 1 2
E2F1 CENPF 0 0 181 312 1 1
E2F1 PTK2 0 0 278 278 1 2
E2F1 XRCC1 0 0 161 185 1 1
E2F1 PHF8 270 0 134 460 1 1
E2F1 SAMD1 0 0 0 152 1 1
E2F1 MBTD1 0 0 54 164 1 1
E2F1 API5 0 0 270 363 1 1
E2F1 MUT 0 0 204 204 1 1
E2F1 BRAF 0 0 97 216 1 2
E2F1 DIABLO 270 0 156 357 1 2
E2F1 KDM2A 270 0 49 352 1 1
E2F1 HBZ 0 0 397 420 1 1
E2F1 INCENP 0 0 47 235 1 1
E2F1 CHD5 0 0 0 174 1 1
E2F1 CENPW 0 0 0 164 1 1
E2F1 CHKA 0 0 334 334 1 1
E2F1 NT5DC2 0 0 0 151 1 1
E2F1 BAZ1B 0 0 95 240 1 1
E2F1 DICER1 0 0 249 281 1 1
E2F1 DYRK3 0 0 0 150 1 1
E2F1 CCNJL 0 0 0 324 1 1
E2F1 POM121 0 0 90 152 1 1
E2F1 HSPA4 0 0 160 183 1 1
E2F1 PXMP4 0 0 107 244 1 1
E2F1 ETV5 0 0 46 183 1 1
E2F1 GATA4 0 0 113 216 1 2
E2F1 SMARCA2 270 0 140 477 1 1
E2F1 NFYA 0 0 218 225 1 1
E2F1 TDP1 0 0 0 186 1 1
E2F1 PPARA 0 0 171 183 1 2
E2F1 VARS 0 0 0 191 1 1
E2F1 LHX8 0 0 0 159 1 1
E2F1 XPO5 0 0 182 231 1 1
E2F1 PDCD4 0 0 244 243 1 2
E2F1 SRRT 0 0 0 164 1 1
E2F1 RAC3 0 0 0 155 1 2
E2F1 CYCS 0 0 274 274 1 2
E2F1 CLSPN 0 0 162 259 1 1
E2F1 FAM83D 0 0 0 248 1 1
E2F1 TRAF6 0 0 112 156 1 2
E2F1 NACC1 0 0 0 317 1 1
E2F1 CDC6 464 900 558 986 1 1
E2F1 EGF 0 0 310 315 1 2
E2F1 SP4 270 0 45 300 1 1
E2F1 PAWR 270 0 0 320 1 1
E2F1 DEPDC1 0 0 0 214 1 1
E2F1 HNF1A 0 0 140 179 1 1
E2F1 TNRC6C 0 650 0 665 1 1
E2F1 TCF19 0 0 81 420 1 1
E2F1 PDGFRB 0 0 124 153 1 2
E2F1 LEF1 270 0 454 605 1 1
E2F1 CDK5 0 0 253 312 1 2
E2F1 CHD1 0 0 0 153 1 1
E2F1 EP300 835 0 496 928 1 2
E2F1 BRWD1 0 0 0 226 1 1
E2F1 RNF123 0 0 74 174 1 1
E2F1 SLBP 0 0 75 150 1 1
E2F1 TARBP2 0 0 81 208 1 1
E2F1 DAG1 0 0 0 158 1 1
E2F1 SMAD3 0 0 254 266 1 2
E2F1 BIRC3 270 0 135 381 1 1
E2F1 ALB 0 0 225 241 1 2
E2F1 CDC23 0 0 106 161 1 1
E2F1 SNAI2 0 0 164 163 1 1
E2F1 YAF2 0 900 0 901 1 1
E2F1 EIF4A1 0 0 75 179 1 1
E2F1 CASP7 486 0 229 590 1 1
E2F1 CUL1 270 0 246 489 1 1
E2F1 C20orf144 0 0 213 213 1 1
E2F1 ELAVL1 0 0 213 251 1 2
E2F1 DSCC1 0 0 96 310 1 1
E2F1 RFX4 0 0 0 237 1 1
E2F1 TAP2 0 0 0 155 1 1
E2F1 GATA1 0 0 202 279 1 1
E2F1 CDK2AP1 0 0 90 183 1 1
E2F1 ALK 0 0 113 163 1 2
E2F1 TADA2B 0 0 0 243 1 1
E2F1 SIRT6 0 0 158 208 1 2
E2F1 DUT 0 0 123 291 1 1
E2F1 ZMYND19 0 0 0 181 1 1
E2F1 CDH1 270 0 323 490 1 2
E2F1 IGF2BP1 0 0 356 422 1 1
E2F1 BUB1B 0 0 216 464 1 1
E2F1 CDK16 0 0 0 243 1 1
E2F1 CUL2 270 0 234 459 1 1
E2F1 RBL1 893 900 862 999 1 1
E2F1 MLIP 0 0 0 208 1 1
E2F1 HAND1 0 0 108 198 1 1
E2F1 IRAK1 0 0 63 153 1 1
E2F1 NCOR2 71 0 145 206 1 1
E2F1 RAF1 0 0 383 405 1 2
E2F1 TDRD1 800 0 0 801 1 1
E2F1 HDAC2 0 0 213 366 1 1
E2F1 CHAF1B 0 0 111 261 1 1
E2F1 SLC7A5 0 0 75 169 1 1
E2F1 NR1H2 0 0 45 260 1 1
E2F1 FAM64A 0 0 59 214 1 1
E2F1 MDM2 486 900 719 984 1 2
E2F1 TP53 678 0 912 975 1 2
E2F1 TGM2 0 0 76 155 1 2
E2F1 TRIM16 270 0 0 270 1 2
E2F1 EGFR 0 0 391 509 1 2
E2F1 CFLAR 0 0 148 201 1 2
E2F1 DLGAP5 0 0 108 299 1 1
E2F1 HTT 0 0 108 192 1 2
E2F1 AMHR2 0 0 108 334 1 1
E2F1 NEDD8 0 0 134 152 1 2
E2F1 SLC2A1 0 0 91 161 1 2
E2F1 ZNF618 0 0 0 185 1 1
E2F1 MYH6 0 0 140 158 1 1
E2F1 CENPA 0 0 165 364 1 1
E2F1 MICA 0 0 171 171 1 1
E2F1 HJURP 0 0 59 253 1 1
E2F1 AATF 0 900 73 909 1 1
E2F1 EIF2AK4 0 0 0 247 1 2
E2F1 RFC3 0 0 150 301 1 1
E2F1 DPCR1 0 0 0 167 1 1
E2F1 CDH2 0 0 160 159 1 1
E2F1 HDAC6 0 0 107 203 1 2
E2F1 APAF1 0 900 367 943 1 2
E2F1 CCNI 0 0 0 293 1 1
E2F1 JAK2 0 0 166 195 1 2
E2F1 CDH3 0 0 272 272 1 1
E2F1 PSMD10 0 0 232 261 1 1
E2F1 MYBL1 0 0 135 438 1 1
E2F1 RAD9A 0 0 268 297 1 1
E2F1 MELK 0 0 235 411 1 1
E2F1 BRD4 0 0 582 873 1 2
E2F1 IBSP 0 0 0 167 1 1
E2F1 IL2RA 0 900 0 900 1 1
E2F1 TOP1 0 0 181 198 1 1
E2F1 RAD18 0 0 57 187 1 1
E2F1 CBX4 0 0 98 159 1 1
E2F1 MAD2L1 0 0 93 299 1 1
E2F1 PURA 486 0 46 549 1 1
E2F1 DSN1 0 0 0 158 1 1
E2F1 CCNH 0 900 285 932 1 1
E2F1 ZBED6 0 0 0 179 1 1
E2F1 PPRC1 0 0 140 181 1 1
E2F1 PPARGC1A 0 0 202 202 1 2
E2F1 HLTF 0 0 0 183 1 1
E2F1 CKS2 0 0 112 328 1 1
E2F1 KIF20B 0 0 44 187 1 1
E2F1 RFC1 0 0 306 364 1 1
E2F1 PRR11 0 0 74 164 1 1
E2F1 RB1CC1 0 0 244 243 1 2
E2F1 CDC5L 0 0 74 271 1 1
E2F1 SLC29A1 0 0 90 197 1 1
E2F1 TCF3 0 0 185 362 1 1
E2F1 CDKN2D 0 0 456 472 1 1
E2F1 TOP2A 0 0 232 436 1 1
E2F1 ZNF367 0 0 0 275 1 1
E2F1 BRCA1 617 0 459 813 1 2
E2F1 PDGFB 0 0 96 185 1 2
E2F1 PBK 0 0 128 412 1 1
E2F1 MDC1 0 0 181 231 1 1
E2F1 L3MBTL4 0 0 0 152 1 1
E2F1 MAGEA11 486 0 108 594 1 1
E2F1 MTA1 270 0 123 379 1 1
E2F1 DDX39A 0 0 0 187 1 1
E2F1 XRCC3 0 0 47 225 1 1
E2F1 POLR2A 0 0 134 161 1 1
E2F1 LAMTOR5 270 0 210 398 1 1
E2F1 FAM72B 0 0 0 158 1 1
E2F1 ZFX 0 0 96 262 1 1
E2F1 SIRT2 0 0 170 188 1 2
E2F1 FNTB 0 0 108 292 1 1
E2F1 DGCR8 0 0 166 185 1 1
E2F1 CREBBP 500 0 193 740 1 1
E2F1 MOV10 0 650 0 656 1 1
E2F1 RUNX1T1 0 0 73 166 1 1
E2F1 SRM 0 0 0 162 1 1
E2F1 ESRRA 0 0 120 180 1 1
E2F1 GSG2 0 0 0 222 1 1
E2F1 CREB1 0 0 294 306 1 2
E2F1 DBF4 0 0 167 212 1 1
E2F1 HIST2H2AC 0 0 181 222 1 1
E2F1 ESPL1 0 0 154 415 1 1
E2F1 GAPDH 0 0 422 450 1 2
E2F1 PML 189 0 138 280 1 2
E2F1 FGFR2 0 0 143 199 1 1
E2F1 POLD2 0 0 82 191 1 1
E2F1 HIST4H4 0 0 285 307 1 1
E2F1 PTBP1 0 0 96 214 1 2
E2F1 ABL1 0 900 193 934 1 1
E2F1 MAP2K7 0 0 324 323 1 1
E2F1 HDAC10 0 0 74 189 1 1
E2F1 BUB1 0 0 229 473 1 1
E2F1 RELA 0 0 321 355 1 2
E2F1 PPP1R12B 0 0 0 202 1 1
E2F1 CARM1 270 0 156 395 1 2
E2F1 NFKB1 385 0 163 498 1 2
E2F1 TNRC6B 0 650 0 657 1 1
E2F1 KLF6 270 0 135 355 1 1
E2F1 PLK4 0 0 218 422 1 1
E2F1 KAT6A 0 0 66 194 1 1
E2F1 HIRA 273 0 0 321 1 1
E2F1 EGR1 0 0 235 278 1 2
E2F1 APP 63 0 117 268 1 2
E2F1 HRAS 0 0 377 449 1 2
E2F1 LRRC45 0 0 0 170 1 1
E2F1 CTNNB1 0 0 416 445 1 2
E2F1 MSH6 0 0 134 236 1 1
E2F1 DESI2 0 0 0 173 1 1
E2F1 BAZ1A 0 0 0 192 1 1
E2F1 NUSAP1 0 0 136 294 1 1
E2F1 ORC1 0 900 82 939 1 1
E2F1 NR1H3 0 0 66 177 1 1
E2F1 NEDD4 0 0 74 162 1 2
E2F1 ORC3 0 0 155 296 1 1
E2F1 MAGEC2 0 0 66 159 1 1
E2F1 KLK3 0 0 158 157 1 1
E2F1 PKIB 192 0 0 192 1 1
E2F1 L3MBTL1 0 0 0 152 1 1
E2F1 CHD1L 0 0 66 247 1 1
E2F1 BRWD3 0 0 0 226 1 1
E2F1 ETS2 0 900 194 919 1 1
E2F1 TROAP 0 0 71 334 1 1
E2F1 BCL2L2-PABPN1 0 0 161 193 1 1
E2F1 STAT1 68 0 213 257 1 2
E2F1 PPP1R26 0 0 328 343 1 1
E2F1 KAT6B 0 0 52 182 1 1
E2F1 NRP2 0 0 0 258 1 1
E2F1 FAM72D 0 0 60 176 1 1
E2F1 HIST1H4F 0 0 285 307 1 1
E2F1 ANKRD52 0 0 74 188 1 1
E2F1 E2F2 393 900 662 946 1 1
E2F1 MTOR 0 0 407 469 1 2
E2F1 SGOL1 0 0 95 189 1 1
E2F1 RAD51 0 900 373 955 1 2
Ontologies
ID Category Term Effect Evidence PubMed
GO:0003677 Molecular Function DNA binding enables IDA
GO:0003677 Molecular Function DNA binding enables IMP
GO:0001216 Molecular Function DNA-binding transcription activator activity enables IDA
GO:0003700 Molecular Function DNA-binding transcription factor activity enables IDA
GO:0003700 Molecular Function DNA-binding transcription factor activity enables TAS
GO:0000981 Molecular Function DNA-binding transcription factor activity, RNA polymerase II-specific enables IBA
GO:0000981 Molecular Function DNA-binding transcription factor activity, RNA polymerase II-specific enables IMP
GO:0000981 Molecular Function DNA-binding transcription factor activity, RNA polymerase II-specific enables ISA
GO:0140297 Molecular Function DNA-binding transcription factor binding enables IPI
GO:0000978 Molecular Function RNA polymerase II cis-regulatory region sequence-specific DNA binding enables IBA
GO:0000987 Molecular Function cis-regulatory region sequence-specific DNA binding enables IDA
GO:0060090 Molecular Function molecular adaptor activity enables EXP
GO:0005515 Molecular Function protein binding enables IPI
GO:0046983 Molecular Function protein dimerization activity enables IEA
GO:0043565 Molecular Function sequence-specific DNA binding enables IDA
GO:0043565 Molecular Function sequence-specific DNA binding enables ISS
GO:1990837 Molecular Function sequence-specific double-stranded DNA binding enables IDA
GO:0000077 Biological Process DNA damage checkpoint signaling involved_in IMP
GO:0006351 Biological Process DNA-templated transcription involved_in ISS
GO:0000082 Biological Process G1/S transition of mitotic cell cycle involved_in IBA
GO:0043276 Biological Process anoikis involved_in IEA
GO:0071466 Biological Process cellular response to xenobiotic stimulus involved_in IEA
GO:0030900 Biological Process forebrain development involved_in IEA
GO:0072332 Biological Process intrinsic apoptotic signaling pathway by p53 class mediator involved_in IEA
GO:0008630 Biological Process intrinsic apoptotic signaling pathway in response to DNA damage involved_in IMP
GO:1990086 Biological Process lens fiber cell apoptotic process involved_in IEA
GO:0048255 Biological Process mRNA stabilization involved_in IDA
GO:0043392 Biological Process negative regulation of DNA binding involved_in IDA
GO:0045892 Biological Process negative regulation of DNA-templated transcription involved_in IDA
GO:0045599 Biological Process negative regulation of fat cell differentiation involved_in ISS
GO:0070345 Biological Process negative regulation of fat cell proliferation involved_in ISS
GO:0000122 Biological Process negative regulation of transcription by RNA polymerase II involved_in IMP
GO:0045893 Biological Process positive regulation of DNA-templated transcription involved_in IDA
GO:0045893 Biological Process positive regulation of DNA-templated transcription involved_in IMP
GO:0043065 Biological Process positive regulation of apoptotic process involved_in IDA
GO:0048146 Biological Process positive regulation of fibroblast proliferation involved_in IMP
GO:0010628 Biological Process positive regulation of gene expression involved_in IDA
GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II involved_in IDA
GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II involved_in IMP
GO:0006355 Biological Process regulation of DNA-templated transcription involved_in IDA
GO:2000045 Biological Process regulation of G1/S transition of mitotic cell cycle acts_upstream_of IMP
GO:0006357 Biological Process regulation of transcription by RNA polymerase II involved_in IBA
GO:0090575 Cellular Component RNA polymerase II transcription regulator complex part_of IPI
GO:0035189 Cellular Component Rb-E2F complex part_of IBA
GO:0035189 Cellular Component Rb-E2F complex part_of IDA
GO:0035189 Cellular Component Rb-E2F complex part_of IPI
GO:0005813 Cellular Component centrosome located_in IDA
GO:0000785 Cellular Component chromatin part_of IDA
GO:0000785 Cellular Component chromatin part_of ISA
GO:0005737 Cellular Component cytoplasm located_in IEA
GO:0005654 Cellular Component nucleoplasm located_in IDA
GO:0005654 Cellular Component nucleoplasm located_in TAS
GO:0005634 Cellular Component nucleus is_active_in IDA
GO:0005634 Cellular Component nucleus located_in IDA
GO:0032991 Cellular Component protein-containing complex part_of IDA
Pathways
Name DB ID
Apoptosis Reactome R-HSA-109581
Intrinsic Pathway for Apoptosis Reactome R-HSA-109606
Activation of NOXA and translocation to mitochondria Reactome R-HSA-111448
Inhibition of replication initiation of damaged DNA by RB1/E2F1 Reactome R-HSA-113501
E2F mediated regulation of DNA replication Reactome R-HSA-113510
Activation of BH3-only proteins Reactome R-HSA-114452
Developmental Biology Reactome R-HSA-1266738
Transcription of E2F targets under negative control by DREAM complex Reactome R-HSA-1362277
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 Reactome R-HSA-1362300
Activation of PUMA and translocation to mitochondria Reactome R-HSA-139915
G0 and Early G1 Reactome R-HSA-1538133
Signaling by NOTCH Reactome R-HSA-157118
Signal Transduction Reactome R-HSA-162582
Cell Cycle Reactome R-HSA-1640170
Disease Reactome R-HSA-1643685
Pre-NOTCH Transcription and Translation Reactome R-HSA-1912408
Pre-NOTCH Expression and Processing Reactome R-HSA-1912422
Generic Transcription Pathway Reactome R-HSA-212436
Cellular responses to stress Reactome R-HSA-2262752
Oxidative Stress Induced Senescence Reactome R-HSA-2559580
Cellular Senescence Reactome R-HSA-2559583
Oncogene Induced Senescence Reactome R-HSA-2559585
Transcriptional Regulation by TP53 Reactome R-HSA-3700989
Mitotic G2-G2/M phases Reactome R-HSA-453274
Mitotic G1 phase and G1/S transition Reactome R-HSA-453279
Programmed Cell Death Reactome R-HSA-5357801
TP53 Regulates Transcription of Cell Cycle Genes Reactome R-HSA-6791312
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest Reactome R-HSA-6804116
G2 Phase Reactome R-HSA-68911
Cyclin E associated events during G1/S transition Reactome R-HSA-69202
G1/S-Specific Transcription Reactome R-HSA-69205
G1/S Transition Reactome R-HSA-69206
Cyclin D associated events in G1 Reactome R-HSA-69231
G1 Phase Reactome R-HSA-69236
S Phase Reactome R-HSA-69242
Cell Cycle, Mitotic Reactome R-HSA-69278
Cyclin A:Cdk2-associated events at S phase entry Reactome R-HSA-69656
RNA Polymerase II Transcription Reactome R-HSA-73857
Gene expression (Transcription) Reactome R-HSA-74160
Transcriptional Regulation by E2F6 Reactome R-HSA-8953750
Cellular responses to stimuli Reactome R-HSA-8953897
Transcriptional regulation of granulopoiesis Reactome R-HSA-9616222
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects Reactome R-HSA-9659787
Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) Reactome R-HSA-9661069
Diseases of mitotic cell cycle Reactome R-HSA-9675126
Aberrant regulation of mitotic cell cycle due to RB1 defects Reactome R-HSA-9687139
Sphingolipid metabolism in senescence (WP5121) WikiPathways WP5121_r119472
DNA IR-double strand breaks and cellular response via ATM (WP3959) WikiPathways WP3959_r118468
Integrated cancer pathway (WP1971) WikiPathways WP1971_r117762
MECP2 and associated Rett syndrome (WP3584) WikiPathways WP3584_r123274
Breast cancer pathway (WP4262) WikiPathways WP4262_r123349
Thyroid stimulating hormone (TSH) signaling pathway (WP2032) WikiPathways WP2032_r122774
Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome (WP4320) WikiPathways WP4320_r123412
Bladder cancer (WP2828) WikiPathways WP2828_r119245
Melanoma (WP4685) WikiPathways WP4685_r123437
Glioblastoma signaling pathways (WP2261) WikiPathways WP2261_r123065
Cell cycle (WP179) WikiPathways WP179_r122978
Adipogenesis (WP236) WikiPathways WP236_r105873
Aryl hydrocarbon receptor pathway (WP2586) WikiPathways WP2586_r121728
Prader-Willi and Angelman syndrome (WP3998) WikiPathways WP3998_r123316
Retinoblastoma gene in cancer (WP2446) WikiPathways WP2446_r116593
DNA IR-damage and cellular response via ATR (WP4016) WikiPathways WP4016_r120667
Overlap between signal transduction pathways contributing to LMNA laminopathies (WP4879) WikiPathways WP4879_r123415
Small cell lung cancer (WP4658) WikiPathways WP4658_r124606
EGF/EGFR signaling pathway (WP437) WikiPathways WP437_r120689
Spinal cord injury (WP2431) WikiPathways WP2431_r120812
DNA damage response (WP707) WikiPathways WP707_r124174
miRNAs involved in DNA damage response (WP1545) WikiPathways WP1545_r118363
Mammary gland development pathway - Involution (Stage 4 of 4) (WP2815) WikiPathways WP2815_r102408
G1 to S cell cycle control (WP45) WikiPathways WP45_r123406
Pancreatic adenocarcinoma pathway (WP4263) WikiPathways WP4263_r123405
Head and neck squamous cell carcinoma (WP4674) WikiPathways WP4674_r123494
H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity (WP3969) WikiPathways WP3969_r123402
Non-small cell lung cancer (WP4255) WikiPathways WP4255_r123348
miRNA regulation of DNA damage response (WP1530) WikiPathways WP1530_r124175
Malignant pleural mesothelioma (WP5087) WikiPathways WP5087_r122659
Transcripts
Accession Version MolecularType Name NCBI Comments
NM_005225 3 mRNA None NC_000020 Reference
XM_047439961 1 mRNA transcript variant X1 NC_000020 Reference