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EPAS1

endothelial PAS domain protein 1
General Information
Name endothelial PAS domain protein 1
Alias
  • endothelial PAS domain-containing protein 1
  • EPAS-1
  • HIF-1-alpha-like factor
  • HIF-1alpha-like factor
  • HIF-2-alpha
  • HIF2-alpha
  • PAS domain-containing protein 2
  • basic-helix-loop-helix-PAS protein MOP2
  • class E basic helix-loop-helix protein 73
  • hypoxia-inducible factor 2 alpha
  • member of PAS protein 2
Gene_family PAS domain containing|Basic helix-loop-helix proteins
organism Homo sapiens
entrez_id 2034
location 2p21
transcript_count 2
exon_count 17
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. [provided by RefSeq, Nov 2009]
    Stringdb Endothelial PAS domain-containing protein 1; Transcription factor involved in the induction of oxygen regulated genes. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression. Activation seems to require recruitment of [...]
    nextProt Transcription factor involved in the induction of oxygen regulated genes. Heterodimerizes with ARNT; heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters (By similarity). Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression. Activation requires recruitment of transcriptional coactivators such as CREBBP and probably EP300. Interaction with redox regulatory protein APEX1 seems to activate CTAD (By similarity).
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
EPAS1 BioGRID VHL GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex; Two-hybrid
EPAS1 BioGRID HSP90AA1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
EPAS1 BioGRID RACK1 GeneID BioGRID Affinity Capture-Western
EPAS1 BioGRID BMAL1 GeneID BioGRID Two-hybrid
EPAS1 BioGRID ARNT GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-crystal Structure; FRET; Reconstituted Complex; Two-hybrid
EPAS1 BioGRID USP33 GeneID BioGRID Affinity Capture-Western
EPAS1 BioGRID TRIM28 GeneID BioGRID Affinity Capture-Western; Co-localization
EPAS1 BioGRID XRCC6 GeneID BioGRID Affinity Capture-Western
EPAS1 BioGRID XRCC5 GeneID BioGRID Affinity Capture-Western
EPAS1 BioGRID PRKDC GeneID BioGRID Affinity Capture-Western; Co-localization
EPAS1 BioGRID JUP GeneID BioGRID Affinity Capture-Western; Co-localization; Reconstituted Complex
EPAS1 BioGRID HDAC2 GeneID BioGRID Affinity Capture-Western
EPAS1 BioGRID HDAC1 GeneID BioGRID Affinity Capture-Western; Co-localization
EPAS1 BioGRID CHD4 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
EPAS1 BioGRID USP37 GeneID BioGRID Affinity Capture-Western
EPAS1 BioGRID USP29 GeneID BioGRID Affinity Capture-Western
EPAS1 BioGRID OTUD7B GeneID BioGRID Affinity Capture-Western
EPAS1 BioGRID USP39 GeneID BioGRID Affinity Capture-Western
EPAS1 BioGRID DDX23 GeneID BioGRID Proximity Label-MS
EPAS1 BioGRID OR6K3 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID RPRD1B GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID CUL2 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID ELOB GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID ELOC GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID S100A9 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID S100A8 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID PRSS1 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID POLR2I GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID POLR2H GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID POLR2G GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID POLR2E GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID POLR2D GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID POLR2C GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID POLR2A GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID H2AC8 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID CSTA GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID EGLN1 GeneID BioGRID Affinity Capture-MS; Reconstituted Complex; Two-hybrid
EPAS1 BioGRID KIF23 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID G0S2 GeneID BioGRID Phenotypic Suppression
EPAS1 BioGRID HILPDA GeneID BioGRID Phenotypic Suppression
EPAS1 BioGRID ALOX15 GeneID BioGRID Phenotypic Suppression
EPAS1 BioGRID HIF1A GeneID BioGRID Affinity Capture-MS; Phenotypic Suppression
EPAS1 BioGRID BMAL2 GeneID BioGRID Two-hybrid
EPAS1 BioGRID USP20 GeneID BioGRID Two-hybrid
EPAS1 BioGRID VIRMA GeneID BioGRID Affinity Capture-RNA
EPAS1 BioGRID EP300 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
EPAS1 BioGRID CREBBP GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
EPAS1 BioGRID PTK6 GeneID BioGRID Co-localization
EPAS1 BioGRID WDR5 GeneID BioGRID Co-localization
EPAS1 BioGRID TET1 GeneID BioGRID Affinity Capture-Western; Co-localization
EPAS1 BioGRID JUN GeneID BioGRID Co-localization; FRET
EPAS1 BioGRID ICAM1 GeneID BioGRID Co-localization
EPAS1 BioGRID KLF6 GeneID BioGRID Co-localization
EPAS1 BioGRID ETV4 GeneID BioGRID FRET
EPAS1 BioGRID ELK1 GeneID BioGRID Affinity Capture-Western
EPAS1 BioGRID KPNA5 GeneID BioGRID Reconstituted Complex
EPAS1 BioGRID KPNA3 GeneID BioGRID Reconstituted Complex
EPAS1 BioGRID KPNB1 GeneID BioGRID Reconstituted Complex
EPAS1 BioGRID KPNA1 GeneID BioGRID Reconstituted Complex
EPAS1 BioGRID NR3C1 GeneID BioGRID Co-localization
EPAS1 BioGRID KPNA6 GeneID BioGRID Reconstituted Complex
EPAS1 BioGRID IKBKG GeneID BioGRID Affinity Capture-Western; Co-localization; FRET; Reconstituted Complex; Two-hybrid
EPAS1 BioGRID USF2 GeneID BioGRID Affinity Capture-Western
EPAS1 BioGRID CREB3L1 GeneID BioGRID Affinity Capture-Western
EPAS1 BioGRID ESR1 GeneID BioGRID Affinity Capture-Western; PCA; Reconstituted Complex
EPAS1 BioGRID MYBL2 GeneID BioGRID Affinity Capture-Western
EPAS1 BioGRID IKBKB GeneID BioGRID Affinity Capture-Western
EPAS1 BioGRID TRIM25 GeneID BioGRID Affinity Capture-RNA
EPAS1 BioGRID HIF3A GeneID BioGRID Affinity Capture-Western
EPAS1 BioGRID EGLN3 GeneID BioGRID Affinity Capture-MS; Reconstituted Complex; Two-hybrid
EPAS1 BioGRID EGLN2 GeneID BioGRID Affinity Capture-MS; Reconstituted Complex
EPAS1 BioGRID SMAD3 GeneID BioGRID Co-localization; Two-hybrid
EPAS1 BioGRID UBC GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID Crebbp GeneID BioGRID Affinity Capture-Western
EPAS1 BioGRID SIRT1 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
EPAS1 BioGRID MAP1LC3A GeneID BioGRID Affinity Capture-Western
EPAS1 BioGRID SQSTM1 GeneID BioGRID Affinity Capture-Western
EPAS1 BioGRID LAMP1 GeneID BioGRID Affinity Capture-Western
EPAS1 BioGRID BATF2 GeneID BioGRID FRET
EPAS1 BioGRID BATF3 GeneID BioGRID FRET
EPAS1 BioGRID BATF GeneID BioGRID FRET
EPAS1 BioGRID DDIT3 GeneID BioGRID FRET
EPAS1 BioGRID DBP GeneID BioGRID FRET
EPAS1 BioGRID NDN GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
EPAS1 BioGRID EPAS1 GeneID BioGRID Affinity Capture-MS; FRET
EPAS1 BioGRID NPM1 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID BBS4 GeneID BioGRID Two-hybrid
EPAS1 BioGRID BBS2 GeneID BioGRID Two-hybrid
EPAS1 BioGRID BBS1 GeneID BioGRID Two-hybrid
EPAS1 BioGRID Arnt GeneID BioGRID Affinity Capture-Western
EPAS1 BioGRID STAT5A GeneID BioGRID Two-hybrid
EPAS1 BioGRID EWSR1 GeneID BioGRID Two-hybrid
EPAS1 BioGRID MED11 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID MED8 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID PSMD1 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID PSMB1 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID MED1 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID PHB1 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID MITF GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
EPAS1 BioGRID EMD GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID CTNNB1 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID DPY30 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID MED10 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID MED25 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID ARID1B GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID WRNIP1 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID MED29 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID MED18 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID TRIM33 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID MED15 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID YTHDF2 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID CNOT7 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID MED4 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID AKAP8L GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID SIN3A GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID CNOT10 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID SSBP3 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID NCAPD3 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID KDM1A GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID CNOT1 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID PHB2 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID DNAJA2 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID DCAF7 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID MED16 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID MED12 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID ARNT2 GeneID BioGRID Affinity Capture-MS; Two-hybrid
EPAS1 BioGRID MED24 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID BAG2 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID MED20 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID MED7 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID MED27 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID MED26 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID MED17 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID MED23 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID GTF3C3 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID MED14 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID BCL7C GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID ELP1 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID XPO1 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID TFAP2A GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
EPAS1 BioGRID MED22 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID SOX10 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
EPAS1 BioGRID SMARCC2 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID SMARCC1 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID SMARCB1 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID SMARCA4 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID SMARCA2 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID DPF2 GeneID BioGRID Affinity Capture-MS
EPAS1 BioGRID ETS1 GeneID BioGRID Affinity Capture-Western
EPAS1 BioGRID KLHL20 GeneID BioGRID Affinity Capture-Western; Two-hybrid
EPAS1 BioGRID TERF2IP GeneID BioGRID Two-hybrid
EPAS1 BioGRID SPP1 GeneID BioGRID Two-hybrid
EPAS1 BioGRID SP1 GeneID BioGRID Affinity Capture-Western
EPAS1 BioGRID ELAVL1 GeneID BioGRID Affinity Capture-RNA
EPAS1 BioGRID STUB1 GeneID BioGRID Affinity Capture-Western
EPAS1 BioGRID HSPA4 GeneID BioGRID Affinity Capture-Western
EPAS1 BioGRID F12 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
EPAS1 BioGRID MCM7 GeneID BioGRID Affinity Capture-Western
EPAS1 BioGRID MCM3 GeneID BioGRID Affinity Capture-Western
EPAS1 BioGRID MAX GeneID BioGRID Affinity Capture-Western
EPAS1 BioGRID MEF2C GeneID BioGRID Two-hybrid
EPAS1 BioGRID APC GeneID BioGRID Two-hybrid
EPAS1 Protein BMAL2 GeneID HPRD
EPAS1 Protein EGLN3 GeneID HPRD
EPAS1 Protein EGLN1 GeneID HPRD
EPAS1 Protein EGLN2 GeneID HPRD
EPAS1 Protein PRKD1 GeneID HPRD
EPAS1 Protein SMAD3 GeneID HPRD
EPAS1 Protein EP300 GeneID HPRD
EPAS1 Protein BMAL1 GeneID HPRD
EPAS1 Protein EIF3E GeneID HPRD
EPAS1 Protein VHL GeneID HPRD
EPAS1 Protein MAX GeneID HPRD
EPAS1 Protein ARNT GeneID HPRD
EPAS1 BioGRID Ruvbl1 GeneID BioGRID Affinity Capture-Western
EPAS1 BioGRID PSMC3 GeneID BioGRID Affinity Capture-Western
EPAS1 Protein ARNT GeneID BIND HLF interacts with Arnt. This interaction was modeled on a demonstrated interaction between mouse HLF and human Arnt.
EPAS1 Protein VHL GeneID BIND The von Hippel-Lindau tumor suppressor protein (pVHL) interacts with Hypoxia inducible factor-2-alpha (HIF-2 alpha)
StringDB
A B experiments database textmining combined score hadb nhadb
EPAS1 SOX1 0 0 46 151 1 1
EPAS1 CEBPB 0 0 181 256 1 2
EPAS1 WTIP 0 600 0 605 1 1
EPAS1 DBP 271 0 0 281 1 2
EPAS1 TBX15 0 0 116 217 1 1
EPAS1 BCL6B 0 0 122 155 1 1
EPAS1 ACO1 0 0 374 766 1 1
EPAS1 POC1A 0 0 81 155 1 1
EPAS1 WNT3 0 0 140 205 1 1
EPAS1 LDHAL6B 0 0 0 163 1 1
EPAS1 ATP6V1E2 0 0 144 197 1 1
EPAS1 SALL4 0 650 74 697 1 1
EPAS1 GSK3B 0 0 108 236 1 2
EPAS1 ARRB1 0 0 402 402 1 1
EPAS1 GUSB 0 0 125 157 1 1
EPAS1 RPS27A 0 600 48 609 1 1
EPAS1 CDKN2A 0 0 291 290 1 2
EPAS1 COL4A5 0 0 86 194 1 1
EPAS1 INSRR 0 0 0 264 1 1
EPAS1 REN 0 0 157 179 1 1
EPAS1 TNFSF13B 0 0 0 512 1 1
EPAS1 IHH 0 0 148 235 1 1
EPAS1 TOX2 0 0 60 195 1 1
EPAS1 CTSS 0 0 46 278 1 1
EPAS1 ACE 0 0 210 234 1 1
EPAS1 CACNA2D3 0 0 62 163 1 1
EPAS1 GPR97 0 0 85 152 1 1
EPAS1 ENSG00000268643 0 0 0 165 1 1
EPAS1 TOM1L1 0 0 67 169 1 1
EPAS1 CYBB 0 0 66 196 1 2
EPAS1 HDAC11 0 0 0 195 1 1
EPAS1 NEK4 0 0 56 201 1 1
EPAS1 VEGFC 0 0 261 377 1 1
EPAS1 AGPAT9 0 0 43 190 1 1
EPAS1 CLEC14A 0 0 142 217 1 1
EPAS1 EGLN1 874 900 759 998 1 1
EPAS1 F3 0 0 83 179 1 1
EPAS1 CASP3 0 0 160 251 1 2
EPAS1 ERBB3 0 0 74 179 1 1
EPAS1 TGFBR3 0 0 150 198 1 1
EPAS1 PTGS2 0 0 209 305 1 2
EPAS1 DCAKD 0 0 122 322 1 1
EPAS1 ZBTB34 0 0 124 214 1 1
EPAS1 MYH7 0 0 74 202 1 1
EPAS1 USP20 118 0 55 198 1 1
EPAS1 ERRFI1 0 0 47 170 1 1
EPAS1 DNAH17 0 0 0 154 1 1
EPAS1 ZBTB47 0 0 0 173 1 1
EPAS1 FOXC1 0 0 147 246 1 1
EPAS1 CSPG4 0 0 108 239 1 1
EPAS1 SPINT1 0 0 81 183 1 1
EPAS1 CMYA5 0 0 76 307 1 1
EPAS1 IL2 0 0 100 161 1 1
EPAS1 COX4I2 0 0 108 175 1 1
EPAS1 NTN4 0 0 53 222 1 1
EPAS1 BECN1 0 0 72 165 1 2
EPAS1 SMARCD3 0 0 0 197 1 1
EPAS1 ABCB1 0 0 136 192 1 2
EPAS1 THBS1 0 0 141 229 1 1
EPAS1 CAMK2B 0 0 0 168 1 1
EPAS1 FLT4 0 0 219 283 1 1
EPAS1 MAPK11 0 0 0 229 1 1
EPAS1 NCCRP1 0 0 0 156 1 1
EPAS1 SLC45A2 0 0 152 244 1 1
EPAS1 RAB19 0 0 73 153 1 1
EPAS1 SFMBT1 0 0 66 154 1 1
EPAS1 SVIL 0 0 43 271 1 1
EPAS1 FOXD1 0 0 113 300 1 1
EPAS1 JMJD6 0 0 96 152 1 1
EPAS1 KRAS 0 0 155 285 1 2
EPAS1 TCEA3 0 0 55 285 1 1
EPAS1 THRB 0 0 210 567 1 1
EPAS1 COL12A1 0 0 57 247 1 1
EPAS1 MYO1C 0 0 0 165 1 1
EPAS1 STAT5A 111 0 127 248 1 1
EPAS1 TCEB1 848 900 414 992 1 1
EPAS1 RXRA 0 0 162 247 1 1
EPAS1 HMOX2 0 0 113 184 1 1
EPAS1 HAND2 0 0 181 187 1 1
EPAS1 SLC24A5 0 0 323 335 1 1
EPAS1 COL4A6 0 0 67 177 1 1
EPAS1 INHBC 0 0 57 156 1 1
EPAS1 FUT1 0 0 123 186 1 1
EPAS1 TIMP2 0 0 73 173 1 1
EPAS1 BTBD1 0 0 113 174 1 1
EPAS1 UBC 131 600 55 682 1 2
EPAS1 TET2 0 0 67 200 1 2
EPAS1 TERT 0 0 146 199 1 2
EPAS1 TYRP1 0 0 137 174 1 1
EPAS1 C3 0 0 53 210 1 2
EPAS1 NEURL3 0 0 226 226 1 1
EPAS1 MMP13 0 0 310 383 1 2
EPAS1 FN1 0 0 209 366 1 2
EPAS1 TBP 0 0 139 192 1 1
EPAS1 TM4SF1 0 0 0 213 1 1
EPAS1 CAMK2A 0 0 0 168 1 2
EPAS1 STXBP4 0 0 57 229 1 1
EPAS1 SETD2 0 0 213 260 1 1
EPAS1 CA12 0 0 385 402 1 1
EPAS1 ISM2 0 0 103 159 1 1
EPAS1 ACVRL1 0 0 113 181 1 1
EPAS1 PDE10A 0 0 95 159 1 1
EPAS1 ESR1 270 0 206 472 1 2
EPAS1 FMNL2 0 0 0 231 1 1
EPAS1 UBE2D2 0 900 54 903 1 1
EPAS1 SMAD7 0 0 82 150 1 1
EPAS1 PDK4 0 0 117 275 1 1
EPAS1 PCNXL2 0 0 67 194 1 1
EPAS1 CSRP1 0 0 95 171 1 1
EPAS1 MYOCD 0 0 126 173 1 1
EPAS1 PLIN2 0 0 167 209 1 2
EPAS1 PDZRN3 0 0 54 223 1 1
EPAS1 PRL 0 0 96 209 1 1
EPAS1 PLCD3 0 0 113 168 1 1
EPAS1 MYBL2 270 0 90 308 1 1
EPAS1 PLCD1 0 0 93 159 1 1
EPAS1 YAP1 0 0 125 193 1 2
EPAS1 LGR5 0 0 123 161 1 1
EPAS1 PRKD1 213 0 0 213 1 1
EPAS1 EDAR 0 0 210 335 1 1
EPAS1 FOXN2 0 0 61 205 1 1
EPAS1 HSF4 0 0 0 224 1 1
EPAS1 MAML3 0 0 284 284 1 1
EPAS1 NME8 0 0 398 398 1 1
EPAS1 PAPOLA 0 0 123 174 1 1
EPAS1 SCARA3 0 0 62 164 1 1
EPAS1 BHLHE41 0 0 273 460 1 1
EPAS1 POU2F3 0 0 74 192 1 1
EPAS1 FTL 0 0 86 181 1 1
EPAS1 OR52A1 0 0 217 252 1 1
EPAS1 SLC2A14 0 0 165 300 1 1
EPAS1 CDX2 0 0 95 223 1 1
EPAS1 E2F3 0 0 114 191 1 1
EPAS1 FBXL5 0 0 107 216 1 1
EPAS1 PSMC3 270 0 327 487 1 1
EPAS1 DOCK8 0 0 106 161 1 1
EPAS1 RORC 0 0 73 178 1 1
EPAS1 COMMD3-BMI1 0 0 134 200 1 1
EPAS1 KIT 0 0 181 255 1 2
EPAS1 NFE2L1 0 0 87 421 1 1
EPAS1 ANP32D 0 0 404 404 1 1
EPAS1 RARB 0 0 137 217 1 1
EPAS1 LDHA 0 0 309 537 1 2
EPAS1 ELL2 0 0 92 159 1 1
EPAS1 ENG 0 0 157 323 1 2
EPAS1 SOX10 131 0 107 285 1 1
EPAS1 EMILIN2 0 0 0 157 1 1
EPAS1 CRB2 0 0 0 206 1 1
EPAS1 NDUFS2 0 0 0 155 1 1
EPAS1 ATP7B 0 0 89 181 1 1
EPAS1 SLC4A4 0 0 52 255 1 1
EPAS1 DNER 0 0 53 156 1 1
EPAS1 IGF2 0 0 207 303 1 1
EPAS1 NPM1 270 0 0 279 1 1
EPAS1 HBB 0 0 320 390 1 1
EPAS1 IL10 0 0 134 225 1 2
EPAS1 SNAI1 0 0 161 389 1 1
EPAS1 RNF128 0 0 123 155 1 1
EPAS1 KDM4C 0 0 107 197 1 1
EPAS1 GDF15 0 0 112 205 1 1
EPAS1 FOSL2 0 0 150 318 1 1
EPAS1 FOSB 0 0 92 217 1 1
EPAS1 EDNRA 0 0 217 297 1 1
EPAS1 EPOR 0 0 374 449 1 1
EPAS1 HSPA9 0 0 0 160 1 1
EPAS1 SGK1 0 0 74 206 1 2
EPAS1 EGR2 0 0 150 201 1 1
EPAS1 LOX 0 0 327 466 1 2
EPAS1 RPS6KB1 0 0 115 251 1 2
EPAS1 ADAMTS12 0 0 98 208 1 1
EPAS1 AGTR1 0 0 170 222 1 1
EPAS1 REM1 0 0 0 218 1 1
EPAS1 SCRT1 0 0 0 180 1 1
EPAS1 TP53I13 0 0 194 194 1 1
EPAS1 PGR 0 0 134 333 1 1
EPAS1 VASH1 0 0 123 163 1 1
EPAS1 SERPINE1 0 0 358 442 1 1
EPAS1 AHR 0 0 362 320 1 2
EPAS1 HOXB7 0 0 57 170 1 1
EPAS1 HSF2 0 0 0 331 1 1
EPAS1 SREBF2 0 0 107 254 1 1
EPAS1 CD274 0 0 134 221 1 2
EPAS1 ALDOC 0 0 117 195 1 1
EPAS1 FAM129B 0 0 0 207 1 1
EPAS1 ANKRD37 0 0 184 212 1 1
EPAS1 COMMD7 0 600 0 600 1 1
EPAS1 PC 0 0 0 160 1 1
EPAS1 SERPINE2 0 0 81 242 1 1
EPAS1 POU1F1 0 0 0 164 1 1
EPAS1 FOXC2 0 0 95 181 1 1
EPAS1 PDLIM7 0 0 0 173 1 1
EPAS1 ABCG2 0 0 180 238 1 1
EPAS1 BCL2L2 0 0 0 200 1 1
EPAS1 DDIT4 0 0 235 313 1 2
EPAS1 DOCK5 0 0 65 164 1 1
EPAS1 SMAD6 0 0 108 167 1 1
EPAS1 FOXA2 0 0 82 336 1 1
EPAS1 LIN28A 0 650 67 665 1 1
EPAS1 CTLA4 0 0 112 152 1 2
EPAS1 PPP1R21 0 0 151 150 1 1
EPAS1 CAT 0 0 140 243 1 2
EPAS1 PLCH1 0 0 66 164 1 1
EPAS1 TAL1 0 0 143 166 1 1
EPAS1 EMP1 0 0 109 284 1 1
EPAS1 ADAMTS3 0 0 385 384 1 1
EPAS1 CAST 0 0 0 182 1 2
EPAS1 BMPR2 0 0 108 224 1 1
EPAS1 FRMD4A 0 0 61 229 1 1
EPAS1 HGF 0 0 157 237 1 2
EPAS1 EGFL7 0 0 55 168 1 1
EPAS1 MCM7 270 0 45 273 1 1
EPAS1 POU5F1 0 650 299 832 1 2
EPAS1 NT5E 0 0 150 272 1 1
EPAS1 SIN3A 131 0 0 457 1 1
EPAS1 MEF2C 130 0 134 243 1 1
EPAS1 VDR 0 0 81 170 1 2
EPAS1 NOTO 0 0 96 168 1 1
EPAS1 NR4A2 0 0 139 220 1 1
EPAS1 KDM3A 0 0 216 251 1 1
EPAS1 PIAS2 270 0 0 270 1 1
EPAS1 MMP3 0 0 158 283 1 1
EPAS1 ANGPTL1 0 0 100 245 1 1
EPAS1 TNF 0 0 210 346 1 2
EPAS1 LCT 0 0 297 302 1 1
EPAS1 NBR1 0 900 64 903 1 2
EPAS1 SMOC1 0 0 0 173 1 1
EPAS1 NFAT5 0 0 0 161 1 1
EPAS1 TFAP2C 0 0 74 200 1 1
EPAS1 C2orf61 0 0 188 188 1 1
EPAS1 PDGFC 0 0 115 179 1 1
EPAS1 DNAH9 0 0 107 313 1 1
EPAS1 SDHAF1 0 0 241 240 1 1
EPAS1 HCRTR1 0 0 329 329 1 1
EPAS1 SNAI3 0 0 0 173 1 1
EPAS1 S100A9 195 0 0 201 1 1
EPAS1 AGT 0 0 150 279 1 1
EPAS1 TFRC 0 0 242 358 1 1
EPAS1 TFAP2A 131 0 103 323 1 1
EPAS1 TNFAIP3 0 0 81 179 1 2
EPAS1 PLOD2 0 0 81 213 1 1
EPAS1 THBS2 0 0 54 157 1 1
EPAS1 ARNTL 682 0 212 798 1 1
EPAS1 ATOX1 0 0 134 179 1 1
EPAS1 PFKFB4 0 0 150 210 1 1
EPAS1 PZP 0 0 0 190 1 1
EPAS1 CASK 0 0 0 216 1 1
EPAS1 AGTRAP 0 0 93 258 1 1
EPAS1 CDH5 0 0 244 379 1 1
EPAS1 FERMT1 0 0 0 164 1 1
EPAS1 GIMAP1 0 0 90 252 1 1
EPAS1 ATF3 0 0 184 309 1 2
EPAS1 P4HA1 0 0 89 247 1 1
EPAS1 FGF3 0 0 73 164 1 1
EPAS1 MYO1A 0 0 0 215 1 1
EPAS1 MAFG 0 0 89 229 1 1
EPAS1 EDNRB 0 0 217 276 1 1
EPAS1 RHOC 0 0 0 150 1 1
EPAS1 CCNG2 0 0 113 165 1 1
EPAS1 SLC7A2 0 0 180 318 1 1
EPAS1 GSK3A 0 0 0 165 1 1
EPAS1 ATOH1 0 0 113 192 1 1
EPAS1 LRRC3B 0 0 83 253 1 1
EPAS1 BIRC5 0 0 153 152 1 2
EPAS1 ARG2 0 0 139 490 1 1
EPAS1 ERBB2 0 0 161 291 1 2
EPAS1 FOXF2 0 0 125 241 1 1
EPAS1 NOTCH2NL 0 0 0 206 1 1
EPAS1 MAGEF1 0 0 143 174 1 1
EPAS1 HBA2 0 0 150 212 1 1
EPAS1 NR1I2 0 0 84 167 1 1
EPAS1 IL6ST 0 0 90 225 1 1
EPAS1 LAMB3 0 0 0 151 1 1
EPAS1 PTHLH 0 0 66 160 1 1
EPAS1 FOXA1 0 0 108 371 1 1
EPAS1 ATF4 0 0 94 247 1 2
EPAS1 CD4 0 0 134 207 1 2
EPAS1 SEMA7A 0 0 96 232 1 1
EPAS1 TGFB2 0 0 150 217 1 1
EPAS1 AKT1 0 0 324 566 1 2
EPAS1 PPARG 0 0 404 474 1 2
EPAS1 ENSG00000267173 0 0 0 162 1 1
EPAS1 MKI67 0 0 82 248 1 2
EPAS1 CFH 0 0 125 247 1 1
EPAS1 ESM1 0 0 134 165 1 1
EPAS1 S100A16 0 0 0 153 1 1
EPAS1 FMOD 0 0 64 162 1 1
EPAS1 LPHN3 0 0 0 225 1 1
EPAS1 RUNX2 0 0 213 293 1 2
EPAS1 FGFR1 0 0 137 190 1 1
EPAS1 IKBKB 270 0 90 389 1 2
EPAS1 LRCH1 0 0 434 442 1 1
EPAS1 ATF6 0 0 95 162 1 2
EPAS1 COL1A2 0 0 103 155 1 1
EPAS1 KLF4 0 650 262 756 1 2
EPAS1 SATB1 0 0 94 154 1 1
EPAS1 COL6A1 0 0 53 168 1 1
EPAS1 COX11 0 0 66 228 1 1
EPAS1 ELK4 0 0 134 224 1 1
EPAS1 COMMD3 0 600 0 604 1 1
EPAS1 LDHB 0 0 74 203 1 1
EPAS1 MMP12 0 0 112 169 1 1
EPAS1 TINAGL1 0 0 0 166 1 1
EPAS1 EIF2S1 0 0 60 174 1 2
EPAS1 MITF 131 0 223 533 1 2
EPAS1 H6PD 0 0 138 232 1 1
EPAS1 NDUFA4L2 0 0 94 234 1 1
EPAS1 KDM5A 0 0 87 191 1 1
EPAS1 ING4 0 0 306 321 1 1
EPAS1 HMOX1 0 0 170 224 1 2
EPAS1 HSD17B12 0 0 134 221 1 1
EPAS1 TCHP 0 0 290 290 1 1
EPAS1 VSIG10L 0 0 164 299 1 1
EPAS1 TTLL3 0 0 89 151 1 1
EPAS1 RB1 0 0 0 413 1 2
EPAS1 CTCF 0 0 143 158 1 1
EPAS1 GTF2B 0 0 57 153 1 1
EPAS1 LAMA3 0 0 75 166 1 1
EPAS1 BNIP3L 0 0 122 252 1 2
EPAS1 ADORA2B 0 0 96 152 1 1
EPAS1 NARFL 0 0 124 212 1 1
EPAS1 OR6K3 274 0 0 274 1 1
EPAS1 TSC2 0 0 142 238 1 2
EPAS1 RBX1 0 600 170 690 1 1
EPAS1 TRRAP 0 0 0 398 1 1
EPAS1 SIAH3 0 0 0 189 1 1
EPAS1 RBM14-RBM4 0 0 0 246 1 1
EPAS1 SRC 0 0 142 261 1 2
EPAS1 SCD 0 0 151 152 1 1
EPAS1 USP8 270 0 0 348 1 1
EPAS1 HSPA12A 0 0 66 165 1 1
EPAS1 MCM3 270 0 47 406 1 1
EPAS1 MB 0 0 134 225 1 2
EPAS1 COMMD10 0 600 0 600 1 1
EPAS1 LRRC2 0 0 82 258 1 1
EPAS1 LIFR 0 0 108 164 1 1
EPAS1 A2M 0 0 66 206 1 1
EPAS1 UGT2B4 0 0 67 160 1 1
EPAS1 ACLY 0 0 86 166 1 1
EPAS1 STAT6 0 0 144 210 1 1
EPAS1 TCF12 0 0 109 446 1 1
EPAS1 PLSCR1 0 0 73 152 1 1
EPAS1 RABGEF1 0 0 432 432 1 1
EPAS1 ALAS2 0 0 213 280 1 1
EPAS1 VHL 989 900 692 999 1 2
EPAS1 FLT1 0 0 419 490 1 1
EPAS1 LTBP2 0 0 0 188 1 1
EPAS1 SART1 0 0 170 525 1 1
EPAS1 DEPDC7 0 0 125 167 1 1
EPAS1 FEN1 0 0 43 168 1 1
EPAS1 HBE1 0 0 142 611 1 1
EPAS1 ESR2 0 0 75 179 1 1
EPAS1 COMMD2 0 600 0 600 1 1
EPAS1 SIRT7 0 0 118 254 1 2
EPAS1 MXI1 0 0 96 218 1 1
EPAS1 LOXL4 0 0 81 167 1 1
EPAS1 ZEB1 0 0 181 251 1 2
EPAS1 ENSG00000258724 0 0 71 188 1 1
EPAS1 EIF3E 270 0 74 420 1 1
EPAS1 ATRN 0 0 58 340 1 1
EPAS1 OCA2 0 0 123 177 1 1
EPAS1 POU3F4 0 0 0 165 1 1
EPAS1 PBX1 0 650 62 664 1 1
EPAS1 TCF7L1 0 0 84 193 1 1
EPAS1 INSR 0 0 46 268 1 1
EPAS1 ETV4 312 0 72 334 1 1
EPAS1 RHOA 0 0 93 165 1 2
EPAS1 EPCAM 0 0 120 153 1 2
EPAS1 CCHCR1 0 0 0 164 1 1
EPAS1 TPM1 0 0 57 177 1 1
EPAS1 KDM1A 131 0 81 182 1 2
EPAS1 CXCL12 0 0 181 210 1 2
EPAS1 ACTB 0 0 294 401 1 2
EPAS1 GAS6 0 0 57 154 1 1
EPAS1 CLDN5 0 0 108 170 1 1
EPAS1 INS 0 0 216 216 1 2
EPAS1 POLR2H 270 0 0 270 1 1
EPAS1 ADAMTS5 0 0 247 353 1 1
EPAS1 DNMT1 0 0 135 176 1 2
EPAS1 PARM1 0 0 124 193 1 1
EPAS1 STUB1 270 0 45 328 1 2
EPAS1 WNT6 0 0 160 160 1 1
EPAS1 B2M 0 0 122 206 1 1
EPAS1 KEAP1 0 0 82 195 1 2
EPAS1 GLO1 0 0 292 300 1 1
EPAS1 SIRT3 0 0 147 222 1 2
EPAS1 PROM1 0 0 233 368 1 2
EPAS1 ARL6 0 0 95 198 1 1
EPAS1 ENO3 0 0 113 355 1 1
EPAS1 ANGPT1 0 0 248 331 1 1
EPAS1 F12 270 0 0 270 1 1
EPAS1 HSFX2 0 0 0 174 1 1
EPAS1 DNAH11 0 0 0 154 1 1
EPAS1 FOSL1 0 0 112 252 1 1
EPAS1 TFEB 0 0 150 229 1 2
EPAS1 ALDOB 0 0 113 160 1 1
EPAS1 FBXW7 0 0 0 173 1 2
EPAS1 PRSS1 198 0 0 198 1 1
EPAS1 ACTN3 0 0 145 177 1 1
EPAS1 CEBPA 0 0 113 194 1 1
EPAS1 COQ7 0 0 0 190 1 1
EPAS1 PATZ1 0 0 0 157 1 1
EPAS1 ARNTL2 483 0 113 618 1 1
EPAS1 SERPINA1 0 0 0 233 1 2
EPAS1 NR2F2 0 0 174 329 1 1
EPAS1 SIGLEC1 0 0 59 189 1 1
EPAS1 DLL4 0 0 203 297 1 1
EPAS1 KPNA6 270 0 0 270 1 1
EPAS1 KPNB1 270 0 59 293 1 1
EPAS1 WDR5 273 0 61 288 1 1
EPAS1 RGCC 0 0 97 172 1 1
EPAS1 MAFB 0 0 145 181 1 1
EPAS1 HEPH 0 0 219 337 1 1
EPAS1 ITPR3 0 0 0 160 1 1
EPAS1 BATF 271 0 45 352 1 1
EPAS1 SLC22A18 0 0 51 220 1 1
EPAS1 TRIM49D2P 0 0 233 232 1 1
EPAS1 RHBDD2 0 0 96 231 1 1
EPAS1 TMPRSS6 0 0 139 232 1 1
EPAS1 SLC16A3 0 0 107 316 1 1
EPAS1 NNMT 0 0 66 174 1 1
EPAS1 HSPA1A 0 0 66 217 1 1
EPAS1 CAV1 0 0 167 272 1 2
EPAS1 GALK2 0 0 96 220 1 1
EPAS1 PCDH7 0 0 97 170 1 1
EPAS1 MNAT1 0 0 57 154 1 1
EPAS1 ADAM8 0 0 108 199 1 1
EPAS1 CAMK1D 0 0 45 150 1 1
EPAS1 IGFBP3 0 0 134 302 1 2
EPAS1 SOX13 0 0 0 157 1 1
EPAS1 MMP2 0 0 193 241 1 2
EPAS1 AGRN 0 0 0 150 1 1
EPAS1 TCF7 0 0 108 240 1 1
EPAS1 TFAM 0 0 0 235 1 2
EPAS1 ANGPT2 0 0 282 380 1 1
EPAS1 ASCL2 0 0 170 176 1 1
EPAS1 PSMD1 131 0 45 175 1 1
EPAS1 TET3 0 0 57 191 1 1
EPAS1 SHH 0 0 96 170 1 2
EPAS1 PNMT 0 0 241 240 1 1
EPAS1 DLEC1 0 0 63 274 1 1
EPAS1 ALLC 0 0 71 159 1 1
EPAS1 CSTA 153 0 0 152 1 1
EPAS1 SURF1 0 0 0 163 1 1
EPAS1 HIST2H3PS2 0 0 155 170 1 1
EPAS1 CDX1 0 0 120 168 1 1
EPAS1 KLF5 0 0 211 282 1 2
EPAS1 STOX2 0 0 0 179 1 1
EPAS1 NR3C1 273 600 211 775 1 1
EPAS1 RPS6KB2 0 0 0 189 1 2
EPAS1 CTGF 0 0 170 272 1 1
EPAS1 POLR2E 215 0 0 215 1 1
EPAS1 SKP2 0 0 48 150 1 2
EPAS1 BCL11A 0 0 123 161 1 1
EPAS1 CAMTA1 0 0 108 270 1 1
EPAS1 AMOT 0 0 74 171 1 1
EPAS1 ARG1 0 0 63 318 1 2
EPAS1 ADIPOQ 0 0 96 152 1 2
EPAS1 ABLIM3 0 0 0 298 1 1
EPAS1 PTGIS 0 0 156 174 1 1
EPAS1 TBX3 0 0 74 195 1 1
EPAS1 DPF2 131 0 0 207 1 1
EPAS1 ENO2 0 0 96 191 1 1
EPAS1 FOXP1 0 650 66 671 1 1
EPAS1 NRP1 0 0 138 248 1 1
EPAS1 ITPR1 0 0 95 193 1 2
EPAS1 CASP9 0 0 74 235 1 2
EPAS1 NANOG 0 900 241 933 1 2
EPAS1 ETS1 270 0 204 716 1 1
EPAS1 IL17A 0 0 73 265 1 2
EPAS1 POLR2D 215 0 0 215 1 1
EPAS1 TINAG 0 0 112 227 1 1
EPAS1 TYR 0 0 134 198 1 2
EPAS1 CCDC82 0 0 124 283 1 1
EPAS1 POTEJ 0 0 0 187 1 1
EPAS1 COL5A1 0 0 91 219 1 1
EPAS1 GNAS 0 0 438 438 1 1
EPAS1 HIF1AN 0 900 359 943 1 1
EPAS1 TIE1 0 0 164 257 1 1
EPAS1 CEBPD 0 0 66 162 1 1
EPAS1 NES 0 0 157 236 1 2
EPAS1 RPTOR 0 0 74 159 1 2
EPAS1 SDHA 0 0 518 521 1 1
EPAS1 SLC25A37 0 0 123 153 1 1
EPAS1 COMMD1 0 600 95 629 1 1
EPAS1 EIF4E2 270 0 412 832 1 1
EPAS1 DCAF7 131 0 0 154 1 1
EPAS1 RABEP1 0 0 537 537 1 1
EPAS1 PGK1 0 0 262 362 1 2
EPAS1 CDK19 0 0 71 221 1 1
EPAS1 NOTCH3 0 0 194 349 1 1
EPAS1 ENPP2 0 0 88 357 1 1
EPAS1 TUBB3 0 0 309 309 1 1
EPAS1 CDK11B 0 0 0 199 1 1
EPAS1 WSCD2 0 0 113 206 1 1
EPAS1 CP 0 0 95 184 1 1
EPAS1 GLI2 0 0 101 156 1 2
EPAS1 TPM4 0 0 0 207 1 1
EPAS1 PTPRJ 0 0 89 254 1 1
EPAS1 KLF12 0 0 160 301 1 1
EPAS1 ZEB2 0 0 212 250 1 1
EPAS1 FRK 0 0 0 152 1 1
EPAS1 STOX1 0 0 87 640 1 1
EPAS1 NR3C2 0 0 90 218 1 1
EPAS1 TCEB3 0 0 329 349 1 1
EPAS1 BDKRB2 0 0 0 218 1 1
EPAS1 TMEM61 0 0 203 222 1 1
EPAS1 RHOB 0 0 151 264 1 1
EPAS1 PCDHGA12 0 0 106 159 1 1
EPAS1 COL5A2 0 0 73 182 1 1
EPAS1 PRKCE 0 0 171 464 1 1
EPAS1 SLC26A7 0 0 71 243 1 1
EPAS1 HMBS 0 0 104 165 1 1
EPAS1 TFAP4 0 0 52 166 1 1
EPAS1 DCUN1D1 0 600 0 600 1 1
EPAS1 SLC9A3R2 0 0 0 151 1 1
EPAS1 SIAH2 0 0 308 307 1 1
EPAS1 FGF7 0 0 109 431 1 1
EPAS1 PLOD1 0 0 112 195 1 1
EPAS1 HK2 0 0 108 312 1 2
EPAS1 SERPINA4 0 0 0 214 1 1
EPAS1 LMNA 0 0 52 169 1 2
EPAS1 SLC2A2 0 0 0 190 1 1
EPAS1 XXYLT1 0 0 91 187 1 1
EPAS1 WHAMM 0 0 0 208 1 1
EPAS1 LAMB2 0 0 0 151 1 1
EPAS1 DDIT3 271 0 124 384 1 2
EPAS1 RBM3 0 0 0 200 1 1
EPAS1 HMCN1 0 0 0 166 1 1
EPAS1 COL2A1 0 0 217 288 1 2
EPAS1 TSC22D3 0 0 95 411 1 1
EPAS1 RBFOX2 0 0 0 152 1 1
EPAS1 IL20RB 0 0 67 226 1 1
EPAS1 MED23 131 0 44 506 1 1
EPAS1 CTBP2 0 0 119 159 1 1
EPAS1 PIN1 0 0 0 150 1 1
EPAS1 GATA3 0 0 184 195 1 1
EPAS1 NR2F1 0 0 108 230 1 1
EPAS1 TCF21 0 0 113 223 1 1
EPAS1 CYBRD1 0 0 265 481 1 1
EPAS1 EDN2 0 0 95 178 1 1
EPAS1 PLIN4 0 0 83 154 1 1
EPAS1 DEAF1 0 0 72 161 1 1
EPAS1 EZH2 0 0 141 208 1 2
EPAS1 STAT3 0 0 266 476 1 2
EPAS1 HTRA1 0 0 46 204 1 1
EPAS1 TGFA 0 0 195 322 1 1
EPAS1 POU5F1B 0 0 73 394 1 1
EPAS1 AGO2 0 0 119 170 1 2
EPAS1 STEAP3 0 0 151 224 1 1
EPAS1 ATP1B1 0 0 123 177 1 1
EPAS1 IL1R1 0 0 66 162 1 1
EPAS1 APEX1 0 900 54 901 1 1
EPAS1 MYC 0 0 375 637 1 2
EPAS1 PDK1 270 0 150 522 1 2
EPAS1 TBC1D24 0 0 107 168 1 1
EPAS1 VWC2 0 0 95 157 1 1
EPAS1 SDHAF2 0 0 566 566 1 1
EPAS1 UBE2D1 0 900 0 901 1 1
EPAS1 HES6 0 0 74 186 1 1
EPAS1 MTF1 0 0 75 254 1 1
EPAS1 USF1 0 0 427 472 1 1
EPAS1 SDHC 0 0 456 467 1 1
EPAS1 COL11A1 0 0 113 168 1 1
EPAS1 TPK1 0 0 0 173 1 1
EPAS1 IGF1R 0 0 122 327 1 2
EPAS1 MEN1 0 0 261 261 1 1
EPAS1 GLS 0 0 95 171 1 2
EPAS1 ARRDC2 0 0 0 213 1 1
EPAS1 NR4A3 0 0 74 549 1 1
EPAS1 TFAP2B 0 0 181 292 1 1
EPAS1 PARVA 0 0 0 177 1 1
EPAS1 HEG1 0 0 155 550 1 1
EPAS1 PIK3CA 0 0 117 169 1 2
EPAS1 TMEM127 0 0 705 705 1 1
EPAS1 ZSCAN10 0 650 0 656 1 1
EPAS1 EIF5B 0 0 651 651 1 1
EPAS1 SSX2B 0 0 261 261 1 1
EPAS1 SMAD4 0 650 123 705 1 2
EPAS1 MYCN 0 0 224 241 1 1
EPAS1 HDAC3 0 0 0 162 1 2
EPAS1 SUCO 0 0 442 454 1 1
EPAS1 FXN 0 0 113 188 1 1
EPAS1 TFR2 0 0 150 305 1 1
EPAS1 SYNPO 0 0 45 155 1 1
EPAS1 NUPR1 0 0 118 178 1 2
EPAS1 DSG2 0 0 94 192 1 1
EPAS1 AKT2 0 0 0 370 1 2
EPAS1 CTSV 0 0 66 161 1 1
EPAS1 NFE2L2 0 0 203 267 1 2
EPAS1 CRIPT 0 0 155 186 1 1
EPAS1 JHDM3C 0 0 107 197 1 1
EPAS1 POU3F2 0 0 73 192 1 1
EPAS1 IGFBP5 0 0 150 235 1 1
EPAS1 PFKL 0 0 126 168 1 1
EPAS1 NOTCH4 0 0 109 168 1 1
EPAS1 LONP1 0 0 95 181 1 1
EPAS1 EP400 0 0 55 151 1 1
EPAS1 DCUN1D5 0 600 0 600 1 1
EPAS1 TGFB3 0 0 161 197 1 1
EPAS1 GRTP1 0 0 201 226 1 1
EPAS1 MYH3 0 0 45 151 1 1
EPAS1 NDN 270 0 0 400 1 1
EPAS1 SSBP3 131 0 68 155 1 1
EPAS1 IFNG 0 0 108 206 1 2
EPAS1 TSTD1 0 0 160 159 1 1
EPAS1 AP3B1 0 0 96 187 1 1
EPAS1 HSPB6 0 0 0 175 1 1
EPAS1 FOXM1 0 0 150 287 1 1
EPAS1 NBL1 0 0 0 213 1 1
EPAS1 MGMT 0 0 141 181 1 2
EPAS1 ANXA5 0 0 125 223 1 2
EPAS1 FGF21 0 0 62 158 1 2
EPAS1 OSMR 0 0 52 166 1 1
EPAS1 EPO 0 900 556 965 1 2
EPAS1 TMEM213 0 0 211 211 1 1
EPAS1 P4HA2 0 0 0 203 1 1
EPAS1 ITPR2 0 0 211 245 1 1
EPAS1 PLVAP 0 0 92 153 1 1
EPAS1 SOX3 0 0 57 161 1 1
EPAS1 KITLG 0 0 140 285 1 1
EPAS1 ACSS2 0 0 95 201 1 1
EPAS1 BCL2L1 0 0 83 282 1 2
EPAS1 TRAF3IP1 0 0 398 398 1 1
EPAS1 EMCN 0 0 122 197 1 1
EPAS1 PELP1 0 800 0 800 1 2
EPAS1 BBS4 270 0 0 270 1 1
EPAS1 SMOC2 0 0 0 151 1 1
EPAS1 ALDOA 0 0 180 223 1 1
EPAS1 TLR4 0 0 113 212 1 2
EPAS1 CDK10 0 0 0 179 1 1
EPAS1 SMAD2 0 650 127 696 1 2
EPAS1 NMNAT1 0 0 62 164 1 1
EPAS1 LMOD1 0 0 81 191 1 1
EPAS1 HYAL2 0 0 113 447 1 1
EPAS1 NF1 0 0 507 530 1 1
EPAS1 NOS2 0 0 233 270 1 2
EPAS1 ATRX 0 0 248 248 1 1
EPAS1 POTEE 0 0 0 187 1 1
EPAS1 JAG2 0 0 60 217 1 1
EPAS1 SP1 486 0 151 555 1 2
EPAS1 IL1B 0 0 213 296 1 2
EPAS1 OAS1 0 0 96 176 1 1
EPAS1 EDN1 0 0 294 419 1 1
EPAS1 HIF1A 309 800 721 868 1 2
EPAS1 KCNJ8 0 0 74 161 1 1
EPAS1 ID1 0 0 140 182 1 1
EPAS1 KIAA1429 270 0 0 270 1 1
EPAS1 EPHA2 0 0 74 178 1 1
EPAS1 HBA1 0 0 150 212 1 1
EPAS1 GJA4 0 0 108 168 1 1
EPAS1 AKR1C3 0 0 108 159 1 1
EPAS1 MAP1LC3A 270 0 48 322 1 2
EPAS1 CDK2 0 0 90 152 1 2
EPAS1 MSI1 0 0 166 265 1 1
EPAS1 ELK1 270 0 0 270 1 1
EPAS1 XPO1 131 0 67 243 1 1
EPAS1 HBG2 0 0 150 385 1 1
EPAS1 DMRTA2 0 0 0 169 1 1
EPAS1 LDHD 0 0 0 176 1 1
EPAS1 TM2D3 0 0 432 432 1 1
EPAS1 ENSG00000278882 0 0 0 206 1 1
EPAS1 NOTCH1 0 0 294 415 1 2
EPAS1 DENND2D 0 0 90 184 1 1
EPAS1 DR1 0 0 57 186 1 1
EPAS1 FGF13 0 0 173 173 1 1
EPAS1 POTEF 0 0 184 308 1 1
EPAS1 KPNA1 270 0 0 270 1 1
EPAS1 C4A 0 0 0 170 1 1
EPAS1 ATF7-NPFF 0 0 0 151 1 1
EPAS1 IL6 0 0 243 391 1 2
EPAS1 PPP1R12A 0 0 0 207 1 1
EPAS1 ACTN4 0 0 0 235 1 1
EPAS1 LDHAL6A 0 0 0 163 1 1
EPAS1 TBX2 0 0 108 225 1 1
EPAS1 ZFHX3 0 0 74 422 1 1
EPAS1 BATF2 271 0 0 368 1 1
EPAS1 PALM2AKAP2 0 0 122 174 1 1
EPAS1 PGM3 0 0 71 173 1 1
EPAS1 SSPN 0 0 0 396 1 1
EPAS1 DNAJA2 131 0 0 183 1 1
EPAS1 FBP1 270 0 0 396 1 1
EPAS1 ZFHX2 0 0 0 177 1 1
EPAS1 CSF1 0 0 75 222 1 1
EPAS1 PRDM1 0 0 95 268 1 1
EPAS1 HDAC1 0 0 107 191 1 2
EPAS1 HIGD1A 0 900 0 905 1 1
EPAS1 PHB2 131 0 48 185 1 1
EPAS1 CRYAB 0 0 0 159 1 2
EPAS1 PBRM1 0 0 241 322 1 1
EPAS1 ADM 0 0 203 310 1 2
EPAS1 SST 0 0 150 163 1 1
EPAS1 PDE3B 0 0 122 150 1 1
EPAS1 ANGPTL3 0 0 52 166 1 1
EPAS1 CHUK 0 0 57 168 1 1
EPAS1 KLF2 0 0 186 217 1 1
EPAS1 WNT2 0 0 134 293 1 1
EPAS1 RBL2 0 0 49 418 1 1
EPAS1 USF2 270 0 53 670 1 1
EPAS1 EHD2 0 0 0 153 1 1
EPAS1 ALOX5 0 0 95 169 1 1
EPAS1 FGFRL1 0 0 120 152 1 1
EPAS1 NOTCH2 0 0 69 229 1 1
EPAS1 EBF3 0 0 0 213 1 1
EPAS1 OSR2 0 0 96 357 1 1
EPAS1 KLHL20 270 0 438 572 1 1
EPAS1 BHLHA15 0 0 0 302 1 1
EPAS1 TET1 270 0 74 591 1 1
EPAS1 TMEM247 0 0 458 457 1 1
EPAS1 MMP14 0 0 150 272 1 1
EPAS1 MED26 131 0 0 452 1 1
EPAS1 HSPA1B 0 0 0 174 1 1
EPAS1 ESRRG 0 0 91 275 1 1
EPAS1 JADE1 0 0 113 192 1 1
EPAS1 FIGF 0 0 166 204 1 1
EPAS1 AFP 0 0 74 162 1 2
EPAS1 POU6F2 0 0 0 164 1 1
EPAS1 SLC40A1 0 0 294 391 1 1
EPAS1 BGN 0 0 0 182 1 1
EPAS1 MED11 131 0 0 198 1 1
EPAS1 MED1 131 0 0 445 1 1
EPAS1 VHLL 0 0 181 790 1 1
EPAS1 GLIS3 0 0 0 202 1 1
EPAS1 SOX7 0 0 95 209 1 1
EPAS1 ATP6V0A4 0 0 95 150 1 1
EPAS1 CFB 0 0 102 195 1 1
EPAS1 PGF 0 0 181 293 1 1
EPAS1 EIF4EBP2 0 0 0 190 1 1
EPAS1 SERPINA7 0 0 0 214 1 1
EPAS1 ALDH1A1 0 0 134 178 1 1
EPAS1 NR6A1 0 0 0 394 1 1
EPAS1 CCDC22 0 600 0 600 1 1
EPAS1 MET 0 0 193 314 1 2
EPAS1 PLXNA4 0 0 47 194 1 1
EPAS1 PRKCH 0 0 0 176 1 1
EPAS1 FTH1 0 0 73 294 1 1
EPAS1 HSPA5 0 0 48 158 1 2
EPAS1 TFE3 0 0 81 316 1 2
EPAS1 SOD2 0 0 147 278 1 2
EPAS1 FOXO1 0 0 213 263 1 2
EPAS1 MOBP 0 0 87 183 1 1
EPAS1 PTK6 273 900 61 928 1 2
EPAS1 APLP1 0 0 91 173 1 1
EPAS1 EXPH5 0 0 66 276 1 1
EPAS1 AMOTL2 0 0 44 158 1 1
EPAS1 HEY2 0 0 180 211 1 1
EPAS1 S100A8 215 0 0 215 1 2
EPAS1 TWIST1 0 0 167 343 1 1
EPAS1 FOS 0 0 230 547 1 2
EPAS1 SUCLG2 0 0 124 168 1 1
EPAS1 ANGPTL4 0 0 218 342 1 1
EPAS1 AJUBA 0 600 0 600 1 1
EPAS1 GTF2F2 0 0 138 174 1 1
EPAS1 LMO1 0 0 93 173 1 1
EPAS1 ADAM17 0 0 151 405 1 1
EPAS1 MCAM 0 0 81 163 1 1
EPAS1 HES4 0 0 136 175 1 1
EPAS1 GLI1 0 0 112 182 1 2
EPAS1 HSPB1 0 0 72 401 1 2
EPAS1 NPC1L1 0 0 63 162 1 1
EPAS1 AKT3 0 0 105 412 1 2
EPAS1 GPX1 0 0 306 306 1 1
EPAS1 RARA 0 0 127 235 1 2
EPAS1 IKBKG 651 0 392 911 1 1
EPAS1 KDM5B 0 0 150 272 1 1
EPAS1 DCUN1D2 0 600 0 600 1 1
EPAS1 POU2F2 0 0 0 164 1 1
EPAS1 SOD3 0 0 74 232 1 1
EPAS1 GATA2 0 0 407 437 1 1
EPAS1 ITGAM 0 0 95 255 1 1
EPAS1 SMARCD2 0 0 0 176 1 1
EPAS1 MPP2 0 0 0 164 1 1
EPAS1 PCDHGC3 0 0 143 193 1 1
EPAS1 MCL1 0 0 53 154 1 2
EPAS1 SMARCA4 131 0 112 220 1 1
EPAS1 SIRT1 270 900 266 956 1 2
EPAS1 IER2 0 0 112 288 1 1
EPAS1 CTSB 0 0 90 183 1 2
EPAS1 GATA6 0 0 170 266 1 1
EPAS1 PTPRZ1 0 0 108 246 1 1
EPAS1 COMMD4 0 600 0 600 1 1
EPAS1 XBP1 0 0 91 184 1 2
EPAS1 GBE1 0 0 95 186 1 1
EPAS1 TP63 0 0 45 178 1 2
EPAS1 STAT2 0 0 122 204 1 1
EPAS1 SOX6 0 0 86 221 1 1
EPAS1 PCCB 0 0 108 172 1 1
EPAS1 CAMTA2 0 0 0 176 1 1
EPAS1 CAMK2G 0 0 66 189 1 1
EPAS1 ATG5 0 0 55 151 1 2
EPAS1 POU6F1 0 0 54 175 1 1
EPAS1 COL10A1 0 0 329 341 1 1
EPAS1 RSF1 0 0 0 150 1 1
EPAS1 PRKAA2 0 0 81 340 1 2
EPAS1 ATOH8 0 0 57 161 1 1
EPAS1 PTEN 0 0 240 452 1 2
EPAS1 VEGFA 270 900 686 978 1 2
EPAS1 NFIA 0 0 90 270 1 1
EPAS1 KDM5C 0 0 137 262 1 1
EPAS1 SREBF1 0 0 134 294 1 1
EPAS1 UBA52 0 600 48 602 1 1
EPAS1 RANBP10 0 0 81 221 1 1
EPAS1 MAPK14 0 0 95 235 1 2
EPAS1 TIMP3 0 0 158 275 1 1
EPAS1 RORB 0 0 72 161 1 1
EPAS1 ENSG00000258947 0 0 176 175 1 1
EPAS1 HFE 0 0 134 228 1 1
EPAS1 LEP 0 0 150 237 1 1
EPAS1 ANGPTL2 0 0 82 160 1 1
EPAS1 PTRF 0 0 45 289 1 1
EPAS1 BMP4 0 0 218 253 1 1
EPAS1 TCF4 0 0 150 334 1 1
EPAS1 COMMD6 0 600 0 600 1 1
EPAS1 RET 0 0 505 514 1 1
EPAS1 FERMT2 0 0 0 152 1 1
EPAS1 GPR116 0 0 210 268 1 1
EPAS1 ATM 0 0 113 209 1 2
EPAS1 THBD 0 0 96 164 1 1
EPAS1 SMAD5 0 0 124 161 1 1
EPAS1 IDH2 0 0 156 214 1 1
EPAS1 CYGB 0 0 66 358 1 1
EPAS1 COL1A1 0 0 156 247 1 2
EPAS1 PLXNB3 0 0 0 157 1 1
EPAS1 RBPJ 0 0 95 166 1 1
EPAS1 PPARGC1B 0 0 150 173 1 1
EPAS1 NAMPT 0 0 141 228 1 2
EPAS1 EFNB2 0 0 129 195 1 1
EPAS1 TACC2 0 0 58 224 1 1
EPAS1 ACTG1 0 0 181 251 1 1
EPAS1 GPALPP1 0 0 173 264 1 1
EPAS1 GLIS1 0 0 66 152 1 1
EPAS1 CDH11 0 0 107 170 1 1
EPAS1 EGLN2 652 900 517 991 1 1
EPAS1 TGFBR2 0 0 108 231 1 1
EPAS1 TJP1 0 0 108 184 1 1
EPAS1 RXRG 0 0 82 253 1 1
EPAS1 ADRA1D 0 0 75 184 1 1
EPAS1 KLF1 0 0 113 165 1 1
EPAS1 HIVEP1 0 0 0 160 1 1
EPAS1 HEY1 0 0 260 322 1 1
EPAS1 EIF4E 0 0 91 243 1 2
EPAS1 GPR124 0 0 95 263 1 1
EPAS1 DCUN1D4 0 600 0 600 1 1
EPAS1 PRKAA1 0 0 270 476 1 2
EPAS1 CCND1 0 0 261 398 1 2
EPAS1 MEIS1 0 0 100 156 1 1
EPAS1 NOS3 0 0 231 363 1 2
EPAS1 ACTA2 0 0 0 172 1 1
EPAS1 JUND 0 0 139 156 1 1
EPAS1 VNN2 0 0 74 154 1 1
EPAS1 WNT9A 0 0 74 234 1 1
EPAS1 FAM132B 0 0 96 260 1 1
EPAS1 RHEB 0 0 0 221 1 2
EPAS1 ATF7 0 0 0 151 1 1
EPAS1 HINFP 0 0 0 179 1 1
EPAS1 KIF23 270 0 0 279 1 1
EPAS1 POLR2I 191 0 0 234 1 1
EPAS1 NR1D1 0 0 157 236 1 2
EPAS1 GNB2L1 0 0 246 379 1 1
EPAS1 E2F8 0 0 103 155 1 1
EPAS1 COL7A1 0 0 0 180 1 1
EPAS1 KLF9 0 0 112 210 1 1
EPAS1 MYO1B 0 0 54 198 1 1
EPAS1 MSI2 0 0 137 256 1 1
EPAS1 EFNA1 0 0 90 224 1 1
EPAS1 UBB 0 600 57 650 1 1
EPAS1 PECAM1 0 0 284 396 1 1
EPAS1 FH 0 0 394 407 1 1
EPAS1 TXN 0 0 108 163 1 1
EPAS1 YPEL1 0 0 0 162 1 1
EPAS1 EXD2 0 0 96 161 1 1
EPAS1 ENSG00000264813 0 0 194 200 1 1
EPAS1 HERC2 0 0 75 216 1 1
EPAS1 ADAMTS4 0 0 322 334 1 1
EPAS1 STARD13 0 0 0 188 1 1
EPAS1 BDNF 0 0 134 167 1 2
EPAS1 SLC1A5 0 0 97 153 1 1
EPAS1 CD44 0 0 195 392 1 2
EPAS1 TNNC2 0 0 0 207 1 1
EPAS1 DKK3 0 0 45 158 1 1
EPAS1 ARNT2 158 800 459 963 1 1
EPAS1 LMCD1 0 0 74 157 1 1
EPAS1 SMARCD1 0 0 0 176 1 1
EPAS1 CDK12 0 0 0 165 1 1
EPAS1 SIX1 0 0 81 289 1 1
EPAS1 SEMA4D 0 0 47 188 1 1
EPAS1 PMP22 0 0 0 159 1 1
EPAS1 MT2A 0 0 124 166 1 1
EPAS1 MPZL3 0 0 90 152 1 1
EPAS1 ACVR2A 0 0 56 566 1 1
EPAS1 SLCO2A1 0 0 67 153 1 1
EPAS1 POU2F1 0 0 53 174 1 1
EPAS1 SCGB3A2 0 0 73 325 1 1
EPAS1 FGF2 0 0 259 368 1 2
EPAS1 ENSG00000196136 0 0 91 516 1 1
EPAS1 TYMP 0 0 141 171 1 1
EPAS1 SOX5 0 0 72 187 1 1
EPAS1 VWF 0 0 141 293 1 1
EPAS1 TNFAIP6 0 0 411 410 1 1
EPAS1 IREB2 0 0 339 582 1 1
EPAS1 POTEI 0 0 0 187 1 1
EPAS1 PGAP1 0 0 61 160 1 1
EPAS1 BYSL 0 0 0 252 1 1
EPAS1 IGF1 0 0 232 285 1 2
EPAS1 SHROOM1 0 0 89 311 1 1
EPAS1 MAPK1 0 0 136 223 1 2
EPAS1 TNMD 0 0 71 214 1 1
EPAS1 ZFHX4 0 0 0 278 1 1
EPAS1 CSF1R 0 0 96 186 1 1
EPAS1 IMPG2 0 0 57 266 1 1
EPAS1 PKM 270 0 334 561 1 1
EPAS1 ESRRB 0 0 95 278 1 1
EPAS1 EPHB4 0 0 117 274 1 1
EPAS1 NOL8 0 0 89 186 1 1
EPAS1 SDC4 0 0 108 192 1 1
EPAS1 CRB1 0 0 0 206 1 1
EPAS1 HSP90AB1 0 0 0 365 1 2
EPAS1 FOXO4 0 0 153 223 1 1
EPAS1 AXL 0 0 107 187 1 2
EPAS1 EIF4EBP1 0 0 108 201 1 2
EPAS1 CYYR1 0 0 154 153 1 1
EPAS1 GPT 0 0 54 191 1 1
EPAS1 MYOF 0 0 0 188 1 1
EPAS1 TCEB2 873 900 384 992 1 1
EPAS1 FOXH1 0 0 74 150 1 1
EPAS1 PINK1 0 0 81 255 1 2
EPAS1 EFEMP1 0 0 95 222 1 1
EPAS1 CCDC39 0 0 75 172 1 1
EPAS1 GJA5 0 0 96 159 1 1
EPAS1 CD34 0 0 211 265 1 2
EPAS1 ECE1 0 0 96 266 1 1
EPAS1 FOXF1 0 0 154 261 1 1
EPAS1 YES1 0 0 48 159 1 1
EPAS1 TH 0 0 154 168 1 2
EPAS1 VEGFB 0 0 229 280 1 1
EPAS1 NID2 0 0 74 222 1 1
EPAS1 TGFBI 0 0 66 192 1 1
EPAS1 SQRDL 0 0 49 177 1 1
EPAS1 AKAP2 0 0 115 162 1 1
EPAS1 FBN1 0 0 82 186 1 1
EPAS1 STC2 0 0 181 204 1 1
EPAS1 CREM 0 0 74 331 1 1
EPAS1 SUMO1 270 0 94 333 1 1
EPAS1 MXD1 0 0 134 255 1 1
EPAS1 ISCU 0 0 166 225 1 1
EPAS1 CA9 0 900 460 960 1 1
EPAS1 UQCRFS1 0 0 0 388 1 1
EPAS1 VCAM1 0 0 125 221 1 1
EPAS1 E2F4 0 0 69 158 1 1
EPAS1 DROSHA 270 0 54 307 1 1
EPAS1 SDHD 0 0 601 625 1 1
EPAS1 CST3 0 0 97 203 1 1
EPAS1 NOX4 0 0 150 284 1 2
EPAS1 ATP13A3 0 0 63 159 1 1
EPAS1 KMT2D 0 0 151 165 1 1
EPAS1 COL4A2 0 0 95 280 1 1
EPAS1 CDK8 0 0 112 255 1 1
EPAS1 ATP7A 0 0 73 228 1 1
EPAS1 CLDN1 0 0 46 162 1 1
EPAS1 SLC2A5 0 0 66 211 1 1
EPAS1 TRIM49D1 0 0 233 232 1 1
EPAS1 NKX3-1 0 0 47 150 1 1
EPAS1 ABCC9 0 0 112 151 1 1
EPAS1 YY1 0 0 113 171 1 1
EPAS1 PXDC1 0 0 0 215 1 1
EPAS1 KDR 0 0 378 500 1 2
EPAS1 MDH2 0 0 459 482 1 1
EPAS1 MGST1 0 0 93 154 1 1
EPAS1 FOXP3 0 0 95 178 1 2
EPAS1 ZNF112 0 0 125 235 1 1
EPAS1 ZNF488 0 0 91 202 1 1
EPAS1 MAP3K6 0 0 0 159 1 1
EPAS1 ARID3B 0 0 67 167 1 1
EPAS1 LUM 0 0 42 157 1 1
EPAS1 STAT5B 0 0 139 175 1 1
EPAS1 TGFB1 0 0 193 269 1 2
EPAS1 RAD54L2 0 0 0 169 1 1
EPAS1 WARS2 0 0 107 261 1 1
EPAS1 SIN3B 0 0 0 188 1 1
EPAS1 MRPL4 0 0 0 213 1 1
EPAS1 CRY1 0 0 113 180 1 1
EPAS1 GATA5 0 0 74 151 1 1
EPAS1 FOXO3 0 0 180 552 1 2
EPAS1 SLC2A4 0 0 136 286 1 1
EPAS1 HNF4A 0 0 143 253 1 1
EPAS1 RNF139 0 0 324 324 1 1
EPAS1 ADRA1B 0 0 170 228 1 1
EPAS1 TERF2IP 295 0 0 295 1 1
EPAS1 FMO2 0 0 61 198 1 1
EPAS1 EWSR1 111 0 103 168 1 1
EPAS1 ELTD1 0 0 113 156 1 1
EPAS1 JMJD4 0 0 103 180 1 1
EPAS1 JDP2 0 0 112 228 1 1
EPAS1 CAMK2D 0 0 96 216 1 1
EPAS1 LPAR1 0 0 397 451 1 1
EPAS1 LDB2 0 0 167 214 1 1
EPAS1 ATRNL1 0 0 0 216 1 1
EPAS1 KPNA5 270 0 0 270 1 1
EPAS1 PTPRC 0 0 101 178 1 1
EPAS1 BCL2L12 0 0 244 243 1 1
EPAS1 FOXA3 0 0 71 208 1 1
EPAS1 SOX9 0 0 264 393 1 1
EPAS1 ICAM1 273 0 81 365 1 2
EPAS1 SPP1 192 0 174 446 1 2
EPAS1 CDKN1A 0 0 150 241 1 2
EPAS1 AR 0 0 155 243 1 2
EPAS1 SOX8 0 0 0 170 1 1
EPAS1 RCAN2 0 0 0 187 1 1
EPAS1 CITED2 0 900 314 933 1 1
EPAS1 TIMP1 0 0 118 205 1 1
EPAS1 LIMS2 0 0 115 168 1 1
EPAS1 MAT2B 0 0 52 157 1 1
EPAS1 POU3F1 0 0 0 165 1 1
EPAS1 ALDH3A1 0 0 113 229 1 1
EPAS1 SERPINA12 0 0 0 214 1 1
EPAS1 EPRS 0 0 43 234 1 1
EPAS1 PRDM14 0 650 57 669 1 1
EPAS1 FGF1 0 0 113 225 1 1
EPAS1 MAPK3 0 0 163 247 1 2
EPAS1 KLF15 0 0 74 200 1 1
EPAS1 MMP9 0 0 216 334 1 2
EPAS1 THY1 0 0 147 181 1 1
EPAS1 SLC11A2 0 0 364 473 1 1
EPAS1 PCK2 0 0 93 156 1 1
EPAS1 BNIP3 0 0 327 511 1 2
EPAS1 SQSTM1 270 0 118 376 1 2
EPAS1 HSP90AA1 270 0 125 488 1 2
EPAS1 CREB3L1 270 0 0 292 1 1
EPAS1 S100A11 0 0 108 154 1 1
EPAS1 PRRX1 0 0 102 174 1 1
EPAS1 RBM4 270 0 819 892 1 1
EPAS1 SOX2 0 900 262 941 1 2
EPAS1 TP73 0 0 0 175 1 2
EPAS1 ELF2 0 0 150 273 1 1
EPAS1 ATF2 0 0 0 172 1 1
EPAS1 COL14A1 0 0 101 178 1 1
EPAS1 DNAJA4 0 0 0 165 1 1
EPAS1 PARD3B 0 0 66 298 1 1
EPAS1 ITGAL 0 0 46 210 1 1
EPAS1 MKX 0 0 46 448 1 1
EPAS1 FZD1 0 0 113 177 1 1
EPAS1 JUN 497 0 233 652 1 2
EPAS1 COL16A1 0 0 45 160 1 1
EPAS1 NCOA2 0 0 113 285 1 1
EPAS1 ZBTB16 0 0 104 300 1 1
EPAS1 BOK 0 0 90 168 1 1
EPAS1 COL18A1 0 0 144 201 1 1
EPAS1 KIF1B 0 0 504 504 1 1
EPAS1 SEMA3G 0 0 56 165 1 1
EPAS1 IRS2 0 0 95 157 1 1
EPAS1 BMP6 0 0 95 195 1 1
EPAS1 KRT34 0 0 67 162 1 1
EPAS1 NCOA3 0 0 61 268 1 1
EPAS1 KLHDC3 0 0 89 297 1 1
EPAS1 PRKACB 0 0 66 192 1 1
EPAS1 COMMD5 0 600 0 600 1 1
EPAS1 MON1B 0 0 180 262 1 1
EPAS1 COL3A1 0 0 108 244 1 1
EPAS1 ASIP 0 0 81 177 1 1
EPAS1 JAG1 0 0 234 354 1 1
EPAS1 FYN 0 0 0 152 1 1
EPAS1 MAX 270 0 464 616 1 2
EPAS1 IGFBP4 0 0 0 162 1 1
EPAS1 RBM4B 0 0 0 536 1 1
EPAS1 SOX17 0 0 174 303 1 1
EPAS1 TBC1D4 0 0 0 207 1 1
EPAS1 SOD1 0 0 111 201 1 2
EPAS1 BMI1 0 0 141 206 1 1
EPAS1 ARNT 990 900 971 999 1 2
EPAS1 LRIF1 0 0 97 236 1 1
EPAS1 SESN2 0 0 386 386 1 2
EPAS1 TPM2 0 0 0 167 1 1
EPAS1 HBZ 0 0 59 176 1 1
EPAS1 CDK11A 0 0 0 199 1 1
EPAS1 BATF3 271 0 57 360 1 1
EPAS1 FSTL3 0 0 157 242 1 1
EPAS1 PRNP 0 0 95 182 1 2
EPAS1 ISM1 0 0 66 227 1 1
EPAS1 COL4A1 0 0 96 261 1 1
EPAS1 P2RX7 0 0 45 209 1 2
EPAS1 HSF5 0 0 114 271 1 1
EPAS1 FRZB 0 0 398 398 1 1
EPAS1 SCRT2 0 0 0 180 1 1
EPAS1 MAPK8 0 0 67 150 1 2
EPAS1 HBG1 0 0 143 380 1 1
EPAS1 RPRD1B 195 0 74 222 1 1
EPAS1 TCHHL1 0 0 108 308 1 1
EPAS1 BHLHE40 0 0 282 345 1 1
EPAS1 GGA1 0 0 297 297 1 1
EPAS1 FLCN 0 0 107 249 1 1
EPAS1 TMEM207 0 0 135 153 1 1
EPAS1 EGF 0 0 205 291 1 2
EPAS1 SENP1 0 0 163 306 1 1
EPAS1 PLAU 0 0 91 175 1 1
EPAS1 IGFBP1 0 0 175 221 1 1
EPAS1 DICER1 0 0 122 183 1 1
EPAS1 TFAP2E 0 0 67 194 1 1
EPAS1 CCNJL 0 0 141 158 1 1
EPAS1 IRF2 0 0 95 191 1 1
EPAS1 HSPA4 270 0 82 419 1 1
EPAS1 ETV5 0 0 86 289 1 1
EPAS1 IER3 0 0 112 171 1 1
EPAS1 TEK 0 0 249 424 1 1
EPAS1 PPARA 0 0 374 449 1 2
EPAS1 COL4A4 0 0 84 192 1 1
EPAS1 HSP90B1 0 0 47 300 1 1
EPAS1 NGB 0 0 123 177 1 1
EPAS1 CSDE1 0 0 362 362 1 1
EPAS1 CCL2 0 0 165 227 1 2
EPAS1 SGK2 0 0 0 157 1 1
EPAS1 ALB 0 0 142 284 1 2
EPAS1 SNAI2 0 0 112 367 1 1
EPAS1 EIF4A1 270 0 68 306 1 1
EPAS1 SCARB1 0 0 450 450 1 1
EPAS1 IL4 0 0 107 191 1 1
EPAS1 WNT9B 0 0 57 203 1 1
EPAS1 PKLR 0 0 167 281 1 1
EPAS1 PDGFRB 0 0 233 335 1 2
EPAS1 NUMB 0 0 94 150 1 1
EPAS1 LEF1 0 0 141 287 1 1
EPAS1 EP300 744 900 293 990 1 2
EPAS1 DAG1 0 0 59 243 1 1
EPAS1 SMAD3 628 0 161 703 1 2
EPAS1 SOX15 0 0 0 162 1 1
EPAS1 BPGM 0 0 270 270 1 1
EPAS1 PPAPDC1B 0 0 0 190 1 1
EPAS1 CRY2 0 0 62 222 1 1
EPAS1 SIRT6 0 0 108 169 1 2
EPAS1 PDE4D 0 0 94 191 1 1
EPAS1 KCNIP3 0 0 43 194 1 1
EPAS1 CDH1 0 0 171 297 1 2
EPAS1 BAI2 0 0 203 267 1 1
EPAS1 IDH1 0 0 242 258 1 1
EPAS1 ALCAM 0 0 64 237 1 1
EPAS1 PDGFRA 0 0 114 171 1 1
EPAS1 MAF 0 0 141 160 1 1
EPAS1 GATA1 0 0 140 162 1 1
EPAS1 MS4A8 0 0 101 165 1 1
EPAS1 LOXL2 0 0 152 240 1 1
EPAS1 WNT1 0 0 95 270 1 2
EPAS1 AQP2 0 0 122 182 1 1
EPAS1 ACVR2B 0 0 0 324 1 1
EPAS1 COMMD8 0 600 0 600 1 1
EPAS1 SOX18 0 0 204 344 1 1
EPAS1 MPP6 0 0 0 164 1 1
EPAS1 TP53 0 0 333 454 1 2
EPAS1 MDM2 0 0 142 308 1 2
EPAS1 TGM2 0 0 57 220 1 2
EPAS1 ALOX15 209 0 0 209 1 1
EPAS1 MYH14 0 0 0 246 1 1
EPAS1 ECM1 0 0 60 158 1 1
EPAS1 EGFR 0 0 307 529 1 2
EPAS1 MRPL48 0 0 144 277 1 1
EPAS1 SLC2A1 0 0 432 520 1 2
EPAS1 NEDD8 0 600 48 622 1 2
EPAS1 LAMP1 270 0 0 301 1 2
EPAS1 CUL2 274 600 270 827 1 1
EPAS1 MED8 131 0 0 219 1 1
EPAS1 RBL1 0 0 0 283 1 1
EPAS1 RREB1 0 0 0 156 1 1
EPAS1 ADAMTS1 0 0 73 178 1 1
EPAS1 LAMA4 0 0 124 177 1 1
EPAS1 GIG25 0 0 91 464 1 1
EPAS1 DNAJA1 0 0 0 214 1 1
EPAS1 KPNA3 270 0 0 270 1 1
EPAS1 HDAC2 0 0 74 155 1 1
EPAS1 WNT4 0 0 87 156 1 1
EPAS1 SLC7A5 0 0 85 165 1 1
EPAS1 CDH2 0 0 70 164 1 1
EPAS1 SLC5A1 0 0 91 170 1 1
EPAS1 JAK2 0 0 210 270 1 2
EPAS1 SEMA3C 0 0 97 165 1 1
EPAS1 NR4A1 0 0 140 221 1 2
EPAS1 PPARD 0 0 122 236 1 1
EPAS1 LIMD1 0 600 55 613 1 1
EPAS1 BRD4 0 0 66 165 1 2
EPAS1 CLU 0 0 100 156 1 2
EPAS1 TMEM100 0 0 112 164 1 1
EPAS1 ZNF532 0 0 172 186 1 1
EPAS1 MMP15 0 0 48 161 1 1
EPAS1 SOX4 0 0 143 255 1 1
EPAS1 MYH6 0 0 123 244 1 1
EPAS1 HBEGF 0 0 66 191 1 1
EPAS1 TRIM8 0 0 156 181 1 1
EPAS1 NCOA1 0 0 90 278 1 1
EPAS1 EIF2AK4 0 0 0 200 1 2
EPAS1 SOX11 0 0 57 176 1 1
EPAS1 DIRC2 0 0 329 544 1 1
EPAS1 WNT5A 0 0 90 200 1 2
EPAS1 CLOCK 0 0 161 297 1 2
EPAS1 PARK2 0 0 0 179 1 1
EPAS1 NR0B2 0 0 84 164 1 1
EPAS1 POLR2G 191 0 48 196 1 1
EPAS1 RAB11FIP5 0 0 0 151 1 1
EPAS1 PPRC1 0 0 42 259 1 1
EPAS1 PCK1 0 0 54 168 1 1
EPAS1 PPARGC1A 0 0 193 296 1 2
EPAS1 CDC14A 0 0 97 196 1 1
EPAS1 ROBO4 0 0 142 247 1 1
EPAS1 ABI3 0 0 102 192 1 1
EPAS1 TEX15 0 0 61 269 1 1
EPAS1 PPP1R3C 0 0 58 176 1 1
EPAS1 EGLN3 675 900 517 992 1 1
EPAS1 TBX5 0 0 137 152 1 1
EPAS1 VASN 0 0 57 225 1 1
EPAS1 GPT2 0 0 0 155 1 1
EPAS1 YTHDF2 131 0 49 202 1 1
EPAS1 UBXN7 0 900 0 900 1 1
EPAS1 MICU1 0 0 218 297 1 1
EPAS1 HNF4G 0 0 0 164 1 1
EPAS1 SERPINA5 0 0 60 151 1 1
EPAS1 CHGA 0 0 233 232 1 1
EPAS1 TMEM45A 0 0 134 167 1 1
EPAS1 INHBA 0 0 155 176 1 1
EPAS1 LRP5 0 0 91 158 1 1
EPAS1 PDZRN4 0 0 0 183 1 1
EPAS1 SLC2A3 0 0 233 357 1 1
EPAS1 HSD17B6 0 0 106 200 1 1
EPAS1 SPARCL1 0 0 64 159 1 1
EPAS1 EBF2 0 0 90 214 1 1
EPAS1 BBS2 192 0 0 192 1 1
EPAS1 MTMR2 0 0 49 195 1 1
EPAS1 NFIX 0 0 0 183 1 1
EPAS1 DAB2IP 0 0 54 156 1 2
EPAS1 SPAG17 0 0 89 186 1 1
EPAS1 TCF3 0 0 60 218 1 1
EPAS1 AQP1 0 0 134 243 1 1
EPAS1 PLXNA2 0 0 0 152 1 1
EPAS1 STK11 0 0 81 156 1 2
EPAS1 PDGFB 0 0 194 358 1 2
EPAS1 BRCA1 0 0 134 216 1 2
EPAS1 AREG 0 0 165 176 1 1
EPAS1 HIST1H2AE 205 0 0 205 1 1
EPAS1 POU3F3 0 0 54 226 1 1
EPAS1 RYR2 0 0 108 263 1 1
EPAS1 CREBBP 413 900 150 984 1 1
EPAS1 PFKFB3 0 0 180 265 1 2
EPAS1 ACO2 0 0 113 173 1 1
EPAS1 NFE2 0 0 73 234 1 1
EPAS1 UBE2D3 0 900 82 905 1 1
EPAS1 ADAM32 0 0 90 227 1 1
EPAS1 SDHB 0 0 557 596 1 1
EPAS1 ESRRA 0 0 112 333 1 1
EPAS1 CREB1 0 0 210 258 1 2
EPAS1 G0S2 209 0 47 236 1 1
EPAS1 APC 66 0 0 156 1 1
EPAS1 HSD11B1 0 0 74 214 1 1
EPAS1 RHOJ 0 0 0 225 1 1
EPAS1 EFHD1 0 0 75 150 1 1
EPAS1 HOPX 0 0 205 221 1 1
EPAS1 POLR2A 275 0 91 335 1 1
EPAS1 COMMD9 0 600 0 600 1 1
EPAS1 PPAPDC1A 0 0 0 190 1 1
EPAS1 HSF1 0 0 0 463 1 2
EPAS1 ZNF385A 0 0 108 302 1 1
EPAS1 SIRT2 0 0 123 155 1 2
EPAS1 PDE3A 0 0 108 150 1 1
EPAS1 ELF5 0 0 91 183 1 1
EPAS1 CDH13 0 0 112 201 1 1
EPAS1 RELA 0 0 154 228 1 2
EPAS1 RORA 0 0 162 217 1 1
EPAS1 NFKB1 0 0 193 224 1 2
EPAS1 KLF6 273 0 144 379 1 1
EPAS1 BNC2 0 0 217 252 1 1
EPAS1 C19orf40 0 0 57 151 1 1
EPAS1 ZMAT4 0 0 94 167 1 1
EPAS1 SLC2A7 0 0 0 167 1 1
EPAS1 CYP1A1 0 0 167 169 1 2
EPAS1 SPSB1 0 0 0 159 1 1
EPAS1 GAPDH 0 0 294 316 1 2
EPAS1 ENO1 0 0 138 233 1 1
EPAS1 FGFR2 0 0 142 341 1 1
EPAS1 CRIM1 0 0 90 173 1 1
EPAS1 EBF1 0 0 150 302 1 1
EPAS1 HAMP 0 0 305 460 1 1
EPAS1 GPR171 0 0 66 209 1 1
EPAS1 FMNL3 0 0 0 152 1 1
EPAS1 TCF7L2 0 0 112 525 1 1
EPAS1 ERG 0 0 70 277 1 1
EPAS1 FKBP8 0 0 88 163 1 1
EPAS1 HIF3A 270 300 731 518 1 1
EPAS1 NR1H3 0 0 72 170 1 1
EPAS1 VAV3 0 0 182 269 1 1
EPAS1 RAB5A 0 0 410 422 1 2
EPAS1 BBS1 192 0 0 192 1 1
EPAS1 TDRD6 0 0 62 270 1 1
EPAS1 POSTN 0 0 142 220 1 1
EPAS1 FZD4 0 0 142 200 1 1
EPAS1 POLR2C 191 0 0 191 1 1
EPAS1 CTSL 0 0 112 210 1 2
EPAS1 ATXN1 0 0 0 187 1 1
EPAS1 CXCL8 0 0 205 251 1 2
EPAS1 NDRG1 0 0 170 361 1 1
EPAS1 EGR1 0 0 259 277 1 2
EPAS1 APP 0 0 74 183 1 2
EPAS1 LURAP1L 0 0 0 159 1 1
EPAS1 ENSG00000258989 0 0 0 176 1 1
EPAS1 HRAS 0 0 301 334 1 2
EPAS1 CTNNB1 131 0 240 735 1 2
EPAS1 COQ9 0 0 97 187 1 1
EPAS1 DDR2 0 0 45 150 1 1
EPAS1 PASK 0 0 133 423 1 1
EPAS1 MMP1 0 0 113 232 1 1
EPAS1 POU5F2 0 0 0 164 1 1
EPAS1 OR5R1 0 0 161 161 1 1
EPAS1 CXCR4 0 0 247 363 1 2
EPAS1 DOHH 0 0 66 208 1 1
EPAS1 CYR61 0 0 160 241 1 1
EPAS1 E2F2 0 0 74 154 1 1
EPAS1 DGKK 0 0 0 286 1 1
EPAS1 MED15 131 0 0 165 1 1
EPAS1 ADAR 0 0 54 157 1 1
EPAS1 MTOR 0 0 261 407 1 2
EPAS1 HILPDA 209 0 150 330 1 1
EPAS1 NPAS2 0 0 123 313 1 1
EPAS1 HSFX1 0 0 0 174 1 1
EPAS1 ACAN 0 0 262 315 1 1
EPAS1 HFE2 0 0 116 243 1 1
EPAS1 OCLN 0 0 104 166 1 1
EPAS1 THRA 0 0 60 304 1 1
EPAS1 SOCS5 0 0 66 239 1 1
EPAS1 STAT1 0 0 167 201 1 2
Ontologies
ID Category Term Effect Evidence PubMed
GO:0001228 Molecular Function DNA-binding transcription activator activity, RNA polymerase II-specific enables IEA
GO:0000981 Molecular Function DNA-binding transcription factor activity, RNA polymerase II-specific enables IBA
GO:0000981 Molecular Function DNA-binding transcription factor activity, RNA polymerase II-specific enables ISA
GO:0000978 Molecular Function RNA polymerase II cis-regulatory region sequence-specific DNA binding enables IEA
GO:0000977 Molecular Function RNA polymerase II transcription regulatory region sequence-specific DNA binding enables IBA
GO:0061629 Molecular Function RNA polymerase II-specific DNA-binding transcription factor binding enables IPI
GO:0005515 Molecular Function protein binding enables IPI
GO:0046982 Molecular Function protein heterodimerization activity enables IDA
GO:0046982 Molecular Function protein heterodimerization activity enables IPI
GO:0043565 Molecular Function sequence-specific DNA binding contributes_to IDA
GO:0001223 Molecular Function transcription coactivator binding enables IPI
GO:0001525 Biological Process angiogenesis involved_in IEA
GO:0001974 Biological Process blood vessel remodeling involved_in IEA
GO:0071456 Biological Process cellular response to hypoxia involved_in IBA
GO:0071456 Biological Process cellular response to hypoxia involved_in IDA
GO:0001892 Biological Process embryonic placenta development involved_in IEA
GO:0002070 Biological Process epithelial cell maturation involved_in IEA
GO:0030218 Biological Process erythrocyte differentiation involved_in IEA
GO:0030324 Biological Process lung development involved_in IEA
GO:0042789 Biological Process mRNA transcription by RNA polymerase II involved_in IEA
GO:0007005 Biological Process mitochondrion organization involved_in IEA
GO:0060586 Biological Process multicellular organismal-level iron ion homeostasis involved_in IEA
GO:0048625 Biological Process myoblast fate commitment involved_in ISS
GO:0042415 Biological Process norepinephrine metabolic process involved_in IEA
GO:0120162 Biological Process positive regulation of cold-induced thermogenesis involved_in ISS
GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II involved_in IDA
GO:0002027 Biological Process regulation of heart rate involved_in IEA
GO:2000434 Biological Process regulation of protein neddylation involved_in IMP
GO:0006357 Biological Process regulation of transcription by RNA polymerase II involved_in IBA
GO:0043619 Biological Process regulation of transcription from RNA polymerase II promoter in response to oxidative stress involved_in IEA
GO:0001666 Biological Process response to hypoxia acts_upstream_of_or_within IDA
GO:0007165 Biological Process signal transduction involved_in TAS
GO:0043129 Biological Process surfactant homeostasis involved_in IEA
GO:0007601 Biological Process visual perception involved_in IEA
GO:0000785 Cellular Component chromatin part_of ISA
GO:0005829 Cellular Component cytosol located_in TAS
GO:0016607 Cellular Component nuclear speck located_in IEA
GO:0005654 Cellular Component nucleoplasm located_in TAS
GO:0005667 Cellular Component transcription regulator complex part_of IDA
Pathways
Name DB ID
Regulation of gene expression by Hypoxia-inducible Factor Reactome R-HSA-1234158
Cellular response to hypoxia Reactome R-HSA-1234174
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha Reactome R-HSA-1234176
Developmental Biology Reactome R-HSA-1266738
Signal Transduction Reactome R-HSA-162582
Macroautophagy Reactome R-HSA-1632852
Cellular responses to stress Reactome R-HSA-2262752
Metabolism of proteins Reactome R-HSA-392499
Transcriptional regulation of pluripotent stem cells Reactome R-HSA-452723
Post-translational protein modification Reactome R-HSA-597592
Signaling by PTK6 Reactome R-HSA-8848021
PTK6 Expression Reactome R-HSA-8849473
Neddylation Reactome R-HSA-8951664
Cellular responses to stimuli Reactome R-HSA-8953897
Signaling by Non-Receptor Tyrosine Kinases Reactome R-HSA-9006927
Autophagy Reactome R-HSA-9612973
Selective autophagy Reactome R-HSA-9663891
Pexophagy Reactome R-HSA-9664873
Adipogenesis (WP236) WikiPathways WP236_r105873
Amplification and expansion of oncogenic pathways as metastatic traits (WP3678) WikiPathways WP3678_r117647
Focal adhesion: PI3K-Akt-mTOR-signaling pathway (WP3932) WikiPathways WP3932_r124527
Type 2 papillary renal cell carcinoma (WP4241) WikiPathways WP4241_r123413
Transcripts
Accession Version MolecularType Name NCBI Comments
NM_001430 5 mRNA None NC_000002 Reference
XM_011532698 3 mRNA transcript variant X1 NC_000002 Reference