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VMA21

vacuolar ATPase assembly factor VMA21
General Information
Name vacuolar ATPase assembly factor VMA21
Alias
  • vacuolar ATPase assembly integral membrane protein VMA21
  • VMA21 vacuolar H+-ATPase homolog
  • VMA21, vacuolar ATPase assembly factor
  • myopathy with excessive autophagy protein
Gene_family
organism Homo sapiens
entrez_id 203547
location Xq28
transcript_count 2
exon_count 4
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez This gene encodes a chaperone for assembly of lysosomal vacuolar ATPase.[provided by RefSeq, Jul 2012]
    Stringdb Vacuolar ATPase assembly integral membrane protein VMA21; Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum
    nextProt Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
VMA21 BioGRID ORF7b GeneID BioGRID Proximity Label-MS
VMA21 BioGRID TGOLN2 GeneID BioGRID Proximity Label-MS
VMA21 BioGRID CANX GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID ATP6V0A2 GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID TMED10 GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID ATP6V1F GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID RAB7A GeneID BioGRID Proximity Label-MS
VMA21 BioGRID RAC2 GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID RHOG GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID RHOC GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID CLEC4D GeneID BioGRID Proximity Label-MS
VMA21 BioGRID TMPRSS11B GeneID BioGRID Proximity Label-MS
VMA21 BioGRID ECSCR GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID ATP6V0D2 GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID CERS3 GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID CMTM8 GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID TMEM199 GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID OR4D2 GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID KIAA2013 GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID PTPN5 GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID TMEM185A GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID ATP10D GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID SMIM11 GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID METTL9 GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID CLEC4A GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID ATP6V0A4 GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID PILRB GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID CTNNA3 GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID SLC43A3 GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID GJB6 GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID TCIRG1 GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID LHFPL2 GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID ATP6AP2 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
VMA21 BioGRID EDEM1 GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID ATP6V0D1 GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID TNFSF18 GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID ATP6V0E1 GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID GP5 GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID GLRB GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID KDSR GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID LPAR1 GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID EDA GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID C3AR1 GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID ATP6V0A1 GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID ATP6V0C GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID ARF5 GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID HSD3B7 GeneID BioGRID Proximity Label-MS
VMA21 BioGRID RPN2 GeneID BioGRID Proximity Label-MS
VMA21 BioGRID ACACA GeneID BioGRID Negative Genetic
VMA21 BioGRID SLC25A46 GeneID BioGRID Proximity Label-MS; Two-hybrid
VMA21 BioGRID RHOT2 GeneID BioGRID Proximity Label-MS
VMA21 BioGRID RMDN3 GeneID BioGRID Proximity Label-MS
VMA21 BioGRID FIS1 GeneID BioGRID Proximity Label-MS
VMA21 BioGRID FKBP8 GeneID BioGRID Proximity Label-MS
VMA21 BioGRID ST7 GeneID BioGRID Proximity Label-MS
VMA21 BioGRID PTPN1 GeneID BioGRID Proximity Label-MS
VMA21 BioGRID YIPF1 GeneID BioGRID Two-hybrid
VMA21 BioGRID INSIG2 GeneID BioGRID Two-hybrid
VMA21 BioGRID PLLP GeneID BioGRID Two-hybrid
VMA21 BioGRID ARL6IP1 GeneID BioGRID Two-hybrid
VMA21 BioGRID YIF1A GeneID BioGRID Two-hybrid
VMA21 BioGRID CDIPT GeneID BioGRID Two-hybrid
VMA21 BioGRID TECR GeneID BioGRID Two-hybrid
VMA21 BioGRID ABHD16A GeneID BioGRID Two-hybrid
VMA21 BioGRID VAMP2 GeneID BioGRID Two-hybrid
VMA21 BioGRID SCD GeneID BioGRID Two-hybrid
VMA21 BioGRID NINJ2 GeneID BioGRID Two-hybrid
VMA21 BioGRID HMOX2 GeneID BioGRID Two-hybrid
VMA21 BioGRID DAGLA GeneID BioGRID Two-hybrid
VMA21 BioGRID BNIP1 GeneID BioGRID Two-hybrid
VMA21 BioGRID ATP6V0B GeneID BioGRID Two-hybrid
VMA21 BioGRID AQP6 GeneID BioGRID Two-hybrid
VMA21 BioGRID CLEC12B GeneID BioGRID Two-hybrid
VMA21 BioGRID RTP2 GeneID BioGRID Two-hybrid
VMA21 BioGRID SLC35E4 GeneID BioGRID Two-hybrid
VMA21 BioGRID LHFPL5 GeneID BioGRID Two-hybrid
VMA21 BioGRID THSD7A GeneID BioGRID Two-hybrid
VMA21 BioGRID LYPD6B GeneID BioGRID Two-hybrid
VMA21 BioGRID ORMDL1 GeneID BioGRID Two-hybrid
VMA21 BioGRID TMEM60 GeneID BioGRID Two-hybrid
VMA21 BioGRID TMEM107 GeneID BioGRID Two-hybrid
VMA21 BioGRID ADAM33 GeneID BioGRID Two-hybrid
VMA21 BioGRID NIPAL3 GeneID BioGRID Two-hybrid
VMA21 BioGRID ATP13A1 GeneID BioGRID Two-hybrid
VMA21 BioGRID OTULINL GeneID BioGRID Proximity Label-MS
VMA21 BioGRID CA9 GeneID BioGRID Proximity Label-MS
VMA21 BioGRID RNF4 GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID EVC2 GeneID BioGRID Proximity Label-MS
VMA21 BioGRID TMEM67 GeneID BioGRID Proximity Label-MS
VMA21 BioGRID TCTN2 GeneID BioGRID Proximity Label-MS
VMA21 BioGRID TMEM216 GeneID BioGRID Proximity Label-MS
VMA21 BioGRID TCTN3 GeneID BioGRID Proximity Label-MS
VMA21 BioGRID TMEM17 GeneID BioGRID Proximity Label-MS
VMA21 BioGRID K3 GeneID BioGRID Affinity Capture-MS
VMA21 BioGRID TMEM9 GeneID BioGRID Co-fractionation
VMA21 BioGRID COA7 GeneID BioGRID Co-fractionation
VMA21 BioGRID SCAF4 GeneID BioGRID Co-fractionation
VMA21 BioGRID NPTN GeneID BioGRID Co-fractionation
VMA21 BioGRID SEPTIN9 GeneID BioGRID Co-fractionation
VMA21 BioGRID PLIN3 GeneID BioGRID Co-fractionation
VMA21 BioGRID SELENBP1 GeneID BioGRID Co-fractionation
VMA21 BioGRID PLAUR GeneID BioGRID Co-fractionation
VMA21 BioGRID OXCT1 GeneID BioGRID Co-fractionation
VMA21 BioGRID ECE1 GeneID BioGRID Co-fractionation
VMA21 BioGRID ELAVL1 GeneID BioGRID Affinity Capture-RNA
StringDB
A B experiments database textmining combined score hadb nhadb
VMA21 NPTN 271 0 0 271 1 1
VMA21 TOMM7 0 0 0 179 1 1
VMA21 MMAA 0 0 0 171 1 1
VMA21 MTNR1B 0 0 0 454 1 1
VMA21 SLC36A1 0 0 0 642 1 1
VMA21 TIMM22 0 0 0 183 1 1
VMA21 ST7 226 0 0 225 1 1
VMA21 LSM7 0 0 0 165 1 1
VMA21 PROKR1 0 0 0 254 1 1
VMA21 TMEM199 684 0 0 820 1 1
VMA21 VTI1A 0 0 0 238 1 1
VMA21 ECE1 271 0 0 271 1 1
VMA21 CLEC12B 208 0 0 208 1 1
VMA21 COMMD10 0 0 0 173 1 1
VMA21 PRG2 0 0 465 465 1 1
VMA21 TBL1XR1 0 0 181 181 1 1
VMA21 HEXA 0 0 0 187 1 1
VMA21 SCAF4 624 0 0 624 1 1
VMA21 RPL12 0 0 468 521 1 1
VMA21 FAT1 0 0 0 426 1 1
VMA21 C11orf73 0 0 0 153 1 1
VMA21 SELENBP1 623 0 0 623 1 1
VMA21 MTNR1A 0 0 0 302 1 1
VMA21 CYP4V2 0 0 0 551 1 1
VMA21 ATP6V1B1 0 0 0 190 1 1
VMA21 LYPD6B 235 0 0 235 1 1
VMA21 OXCT1 613 0 0 613 1 1
VMA21 BAK1 0 0 0 272 1 2
VMA21 TMEM230 0 0 0 155 1 1
VMA21 MCUR1 0 0 0 213 1 1
VMA21 ATP6V0D1 477 0 0 592 1 1
VMA21 GAA 0 0 0 167 1 2
VMA21 ATP6V0C 676 0 0 686 1 1
VMA21 PDF 0 0 0 157 1 1
VMA21 NME3 0 0 0 159 1 1
VMA21 GUK1 0 0 0 171 1 1
VMA21 EDA 195 0 0 195 1 1
VMA21 ATP6V1F 0 0 0 242 1 1
VMA21 DGUOK 0 0 0 165 1 1
VMA21 KRTCAP2 0 0 0 183 1 1
VMA21 FAT2 0 0 0 610 1 1
VMA21 TMEM9 655 0 0 655 1 1
VMA21 AGO4 0 0 193 193 1 1
VMA21 RPS17 0 0 213 348 1 1
VMA21 MRPS24 0 0 0 183 1 1
VMA21 TRAPPC9 0 0 0 183 1 1
VMA21 RNF4 270 0 0 270 1 1
VMA21 LSM5 0 0 0 151 1 1
VMA21 EMC4 0 0 0 179 1 1
VMA21 EMC7 0 0 0 157 1 1
VMA21 FUNDC2 0 0 0 165 1 1
VMA21 RCN1 0 0 323 323 1 1
VMA21 SEPT9 271 0 0 305 1 1
VMA21 PLAUR 619 0 0 619 1 1
VMA21 ATP6AP2 687 0 0 833 1 1
VMA21 EMC3 0 0 0 153 1 1
VMA21 TRAPPC11 0 0 0 190 1 1
VMA21 ZNF467 0 0 342 443 1 1
VMA21 AGL 0 0 230 234 1 1
VMA21 SEC61G 0 0 0 211 1 1
VMA21 COQ3 0 0 0 229 1 1
VMA21 ATP6V0D2 676 0 0 779 1 1
VMA21 ATP6V0A2 458 0 218 623 1 1
VMA21 ATP6AP1 0 0 0 311 1 1
VMA21 CP 0 0 0 364 1 1
VMA21 COA7 619 0 0 619 1 1
VMA21 DRD2 0 0 0 190 1 1
VMA21 PFDN5 0 0 0 172 1 1
VMA21 ATP6V0A1 0 0 0 222 1 1
VMA21 CRYBA1 0 0 0 250 1 1
VMA21 HOOK1 0 0 270 270 1 1
VMA21 KLHL40 0 0 0 183 1 1
VMA21 ELAVL1 42 0 92 164 1 2
VMA21 CCDC115 0 0 0 168 1 1
VMA21 SLC36A4 0 0 0 403 1 1
VMA21 OLFM1 0 0 252 252 1 1
VMA21 CDHR4 0 0 0 187 1 1
VMA21 ATP6AP1L 0 0 0 234 1 1
VMA21 ZBTB8OS 0 0 0 171 1 1
VMA21 FAT3 0 0 0 241 1 1
VMA21 MRPS10 0 0 0 171 1 1
VMA21 PLIN3 271 0 0 274 1 1
VMA21 HEPHL1 0 0 0 364 1 1
VMA21 DCHS2 0 0 0 187 1 1
VMA21 TOR1B 0 0 0 171 1 1
VMA21 COQ7 0 0 0 183 1 1
VMA21 BLOC1S5 0 0 0 155 1 1
VMA21 PROKR2 0 0 0 154 1 1
VMA21 IER3IP1 0 0 0 155 1 1
VMA21 CSTF2 0 0 234 302 1 1
VMA21 MTUS1 0 0 260 260 1 1
VMA21 SLC36A2 0 0 0 302 1 1
VMA21 TCIRG1 0 0 0 225 1 1
VMA21 NUDT21 0 0 504 508 1 1
VMA21 CPSF6 0 0 217 260 1 1
VMA21 WDR59 0 0 0 183 1 1
VMA21 GFM2 0 0 0 183 1 1
VMA21 HEPH 0 0 0 364 1 1
VMA21 ATP6V0A4 0 0 0 270 1 1
VMA21 LOH12CR1 0 0 0 169 1 1
VMA21 SLC36A3 0 0 0 250 1 1
VMA21 PEX16 0 0 0 183 1 1
VMA21 ATP6V0E1 623 0 0 623 1 1
VMA21 SNAPIN 0 0 0 153 1 1
VMA21 KIAA2013 603 0 0 662 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0005515 Molecular Function protein binding enables IPI
GO:0043462 Biological Process regulation of ATP-dependent activity involved_in TAS
GO:0070072 Biological Process vacuolar proton-transporting V-type ATPase complex assembly involved_in IBA
GO:0070072 Biological Process vacuolar proton-transporting V-type ATPase complex assembly involved_in TAS
GO:0012507 Cellular Component ER to Golgi transport vesicle membrane located_in IEA
GO:0005789 Cellular Component endoplasmic reticulum membrane is_active_in IBA
GO:0033116 Cellular Component endoplasmic reticulum-Golgi intermediate compartment membrane located_in IEA
GO:0005764 Cellular Component lysosome located_in IDA
Pathways
Name DB ID
Transcripts
Accession Version MolecularType Name NCBI Comments
NM_001363810 1 mRNA transcript variant 2 NC_000023 Reference
NM_001017980 4 mRNA transcript variant 1 NC_000023 Reference