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EPO

erythropoietin
General Information
Name erythropoietin
Alias
  • erythropoietin
  • epoetin
Gene_family Receptor ligands
organism Homo sapiens
entrez_id 2056
location 7q22.1
transcript_count 1
exon_count 5
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez This gene encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The encoded protein is mainly synthesized in the kidney, secreted into the blood plasma, and binds to the erythropoietin receptor to promote red blood cell production, or erythropoiesis, in the bone marrow. Expression of this gene is upregulated under hypoxic conditions, in turn leading to increased erythropoiesis and enhanced oxygen-carrying capacity of the blood. Expression of this gene has also been observed in brain and in the eye, and elevated expression levels have been observed in diabetic retinopathy and ocular hypertension. Recombinant forms of the encoded protein exhibit neuroprotective activity against a variety of potential brain injuries, as well as antiapoptotic functions in several tissue types, and have been used in the treatment of anemia and to enhance the efficacy of cancer therapies. [provided by RefSeq, Aug 2017]
    Stringdb Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3; Endogenous ligands
    nextProt Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3.
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
EPO BioGRID S100P GeneID BioGRID Reconstituted Complex
EPO BioGRID S100A6 GeneID BioGRID Reconstituted Complex
EPO BioGRID S100A2 GeneID BioGRID Reconstituted Complex
EPO BioGRID Cish GeneID BioGRID Reconstituted Complex
EPO BioGRID KIAA0319L GeneID BioGRID Affinity Capture-MS
EPO BioGRID B4GALT5 GeneID BioGRID Affinity Capture-MS
EPO BioGRID B4GALT6 GeneID BioGRID Affinity Capture-MS
EPO BioGRID PTPRS GeneID BioGRID Affinity Capture-MS
EPO BioGRID MAN1A1 GeneID BioGRID Affinity Capture-MS
EPO BioGRID EPOR GeneID BioGRID Affinity Capture-Luminescence; Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex; Two-hybrid
EPO BioGRID HIF1A GeneID BioGRID Reconstituted Complex
EPO BioGRID USF2 GeneID BioGRID Co-localization
EPO BioGRID Epor GeneID BioGRID Reconstituted Complex
EPO BioGRID GINM1 GeneID BioGRID Affinity Capture-MS
EPO BioGRID EP300 GeneID BioGRID Two-hybrid
EPO Protein EPOR GeneID HPRD
EPO Nucleotide SIM2 GeneID BIND SIM2 interacts with the hypoxia-inducible enhancer of the EPO gene. This interaction was modeled on a demonstrated interaction between mouse SIM2 and the human EPO enhancer.
EPO Nucleotide None None BIND HLF/Arnt heterodimer interacts with the hypoxia-inducible enhancer of the Epo gene.
EPO Nucleotide None None BIND HIF1-alpha/Arnt heterodimer interacts with the hypoxia-inducible enhancer of the Epo gene.
EPO Nucleotide RB1 GeneID BIND RB1 (pRB) interacts with the EPO gene 3(prime) enhancer.
EPO Nucleotide HIF1A GeneID BIND HIF1A (HIF-1-alpha) interacts with the EPO gene 3(prime) enhancer.
EPO Protein EPOR GeneID BIND Interaction between EPOR (PDB ID: 1EER_B) and EPO (PDB ID: 1EER_A).
EPO Protein EPOR GeneID BIND Interaction between EPOR (PDB ID: 1EER_C) and EPO (PDB ID: 1EER_A).
StringDB
A B experiments database textmining combined score hadb nhadb
EPO NOS3 0 0 601 606 1 2
EPO FLT3LG 0 0 465 475 1 1
EPO SEMA3A 0 0 181 232 1 1
EPO EPHA1 0 0 601 614 1 1
EPO INS-IGF2 0 0 0 189 1 1
EPO CD274 0 0 161 161 1 2
EPO FSHR 0 0 0 221 1 1
EPO CSF2RB 0 600 587 827 1 1
EPO CCND1 0 0 328 328 1 2
EPO WDR77 0 0 162 193 1 1
EPO FGF5 0 0 0 212 1 1
EPO CD19 0 0 371 371 1 1
EPO FAM132B 0 0 709 719 1 1
EPO RGL3 0 0 0 163 1 1
EPO ABCG2 0 0 170 169 1 1
EPO EPHB1 0 0 391 392 1 1
EPO IRS1 0 0 209 209 1 2
EPO CBL 0 900 284 925 1 1
EPO LOX 0 0 294 294 1 2
EPO EPOR 897 900 990 999 1 1
EPO EDNRA 0 0 242 241 1 1
EPO HMGCR 0 0 136 167 1 1
EPO NTRK1 0 0 340 340 1 1
EPO KLF1 0 0 557 570 1 1
EPO ALAD 0 0 385 384 1 1
EPO PGR 0 0 171 171 1 1
EPO EIF4E 0 0 209 209 1 2
EPO SERPINE1 0 0 393 392 1 1
EPO AHR 0 0 284 284 1 2
EPO IDUA 0 0 135 153 1 1
EPO ETV6 0 0 204 204 1 1
EPO RPS6KB1 0 0 282 282 1 2
EPO OLIG2 0 0 170 169 1 1
EPO HBD 0 0 207 207 1 1
EPO REM1 0 0 0 248 1 1
EPO AGTR1 0 0 261 261 1 1
EPO FCGR1A 0 0 415 430 1 1
EPO RUNX1 0 0 122 155 1 2
EPO TAL1 0 0 391 418 1 1
EPO EMP1 0 0 310 309 1 1
EPO GFI1 0 0 184 185 1 1
EPO CAT 0 0 421 437 1 2
EPO PECAM1 0 0 494 498 1 1
EPO NKX2-5 0 0 181 181 1 1
EPO ENSG00000264813 0 0 684 684 1 1
EPO HGF 0 0 470 480 1 2
EPO POU5F1 0 0 267 304 1 2
EPO FH 0 0 181 181 1 1
EPO NPHS2 0 0 146 176 1 2
EPO TXN 0 0 249 248 1 1
EPO FGF16 0 0 108 343 1 1
EPO MDK 0 0 95 151 1 1
EPO MYB 0 0 370 385 1 1
EPO CD38 0 0 370 370 1 2
EPO DDIT4 0 0 246 245 1 2
EPO HPRT1 0 0 261 261 1 1
EPO CTLA4 0 0 260 260 1 2
EPO UROS 0 0 125 157 1 1
EPO F8 0 0 234 281 1 1
EPO EFNA1 0 0 501 507 1 1
EPO SYNM 0 0 0 212 1 1
EPO GBA 0 0 244 243 1 1
EPO PSMA7 0 0 170 169 1 1
EPO LDLR 0 0 150 183 1 2
EPO LIN28A 0 0 150 175 1 1
EPO PDGFC 0 0 156 155 1 1
EPO IGBP1 0 0 57 154 1 1
EPO RBFOX3 0 0 336 351 1 1
EPO IL23R 0 600 47 602 1 1
EPO ACVR2A 0 0 141 195 1 1
EPO MFHAS1 0 0 160 166 1 1
EPO TMSB4X 0 0 195 201 1 1
EPO ATXN2L 0 0 398 398 1 1
EPO GH1 0 800 282 850 1 1
EPO CASP2 0 0 145 163 1 1
EPO VDR 0 0 233 232 1 2
EPO WISP1 0 0 166 172 1 1
EPO ARNT2 0 0 180 203 1 1
EPO IL1RN 0 0 181 181 1 1
EPO MMP3 0 0 150 281 1 1
EPO IL7 0 0 499 501 1 1
EPO NT5E 0 0 335 344 1 1
EPO MEF2C 0 0 150 173 1 1
EPO CD44 0 0 358 358 1 2
EPO BDNF 0 0 595 632 1 2
EPO HSPA2 0 0 306 306 1 1
EPO TNF 0 0 635 657 1 2
EPO RHAG 0 0 181 216 1 1
EPO EPHB6 0 0 425 424 1 1
EPO EFNA3 0 0 154 153 1 1
EPO MERTK 0 0 123 165 1 1
EPO CCND3 0 0 129 183 1 1
EPO SOCS1 0 0 343 343 1 1
EPO FABP1 0 0 167 208 1 1
EPO BTK 0 900 163 915 1 1
EPO MAPK1 0 0 195 200 1 2
EPO IGF1 0 0 654 668 1 2
EPO ITIH4 0 0 181 181 1 1
EPO CSF1R 0 0 323 323 1 1
EPO APOB 0 0 203 261 1 2
EPO MMP27 0 0 0 189 1 1
EPO ACSBG2 0 0 0 248 1 1
EPO PLA2G3 0 0 0 190 1 1
EPO SOCS4 0 0 261 261 1 1
EPO NRN1 0 0 134 157 1 1
EPO CDH5 0 0 370 370 1 1
EPO RETN 0 0 160 159 1 1
EPO ITPA 0 0 327 327 1 1
EPO PKM 0 0 170 169 1 1
EPO CNR1 0 0 123 214 1 1
EPO EPHB4 297 0 579 692 1 1
EPO SLC35A1 0 0 113 202 1 1
EPO MMP8 0 0 87 158 1 1
EPO SRSF2 0 0 195 195 1 1
EPO PRLR 0 600 477 782 1 1
EPO ABCB10 0 0 134 171 1 1
EPO FGF2 0 0 566 580 1 2
EPO ENSG00000196136 0 0 90 151 1 1
EPO SOS1 0 900 71 904 1 1
EPO ATP12A 0 0 334 334 1 1
EPO SPN 0 0 193 193 1 1
EPO PIK3C2G 0 0 642 642 1 1
EPO GCG 0 0 376 376 1 1
EPO TNNT2 0 0 150 168 1 1
EPO IREB2 0 0 404 466 1 1
EPO VWF 0 0 470 470 1 1
EPO IL5 0 0 455 455 1 1
EPO PRDX2 0 0 294 294 1 1
EPO AGT 0 0 263 324 1 1
EPO TFRC 0 0 739 744 1 1
EPO FLVCR1 0 0 282 287 1 1
EPO IFNAR1 0 600 181 658 1 1
EPO CCND2 0 0 150 170 1 1
EPO KLK4 0 0 203 203 1 1
EPO SHBG 0 0 180 179 1 1
EPO RHD 0 0 241 240 1 1
EPO HBA2 0 0 293 293 1 1
EPO ACVR1B 0 0 144 197 1 1
EPO VEGFB 0 0 241 240 1 1
EPO TH 0 0 335 336 1 2
EPO NGF 0 0 470 506 1 2
EPO CD34 0 0 752 756 1 2
EPO ERBB2 0 0 373 373 1 2
EPO ARG2 0 0 202 202 1 1
EPO TLR9 0 0 155 154 1 2
EPO MGAM 0 0 193 193 1 1
EPO HAO1 0 0 74 170 1 1
EPO IL6ST 0 600 108 627 1 1
EPO EIF4EBP1 0 0 244 243 1 2
EPO EDNRB 0 0 171 171 1 1
EPO RTN4 0 0 245 254 1 1
EPO FGG 0 0 0 203 1 1
EPO CXCL10 0 0 241 240 1 2
EPO FGF3 0 0 0 302 1 1
EPO ALAS1 0 0 161 218 1 1
EPO P4HA1 0 0 123 195 1 1
EPO FOXO4 0 0 226 279 1 1
EPO ASPG 0 0 111 181 1 1
EPO IFNGR2 0 600 58 607 1 1
EPO TCEB2 0 0 382 382 1 1
EPO MAG 0 0 135 162 1 1
EPO SIRT4 0 0 229 228 1 1
EPO GJA1 0 0 235 235 1 1
EPO GPT 0 0 458 457 1 1
EPO IL11 0 0 602 602 1 1
EPO PDE5A 0 0 229 234 1 1
EPO XIAP 0 0 194 209 1 2
EPO GMFG 0 0 0 303 1 1
EPO CEBPG 0 0 43 191 1 1
EPO RUNX2 0 0 233 232 1 2
EPO IFNLR1 0 600 0 600 1 1
EPO NOX4 0 0 282 282 1 2
EPO CST3 0 0 394 394 1 1
EPO SDHD 0 0 145 164 1 1
EPO COL1A2 0 0 305 305 1 1
EPO ACE2 0 0 150 235 1 2
EPO BMX 0 0 108 174 1 1
EPO IKBKB 0 0 150 172 1 2
EPO KLF4 0 0 243 242 1 2
EPO DUOX1 0 0 167 167 1 1
EPO VIP 0 0 167 167 1 1
EPO FGFR1 0 0 245 244 1 1
EPO NTRK2 0 0 235 240 1 1
EPO ATP7A 0 0 122 152 1 1
EPO CA9 0 0 455 474 1 1
EPO ISCU 0 0 163 178 1 1
EPO CD4 0 0 503 503 1 2
EPO ATF4 0 0 171 171 1 2
EPO VCAM1 0 0 453 453 1 1
EPO PTHLH 0 0 218 218 1 1
EPO FAS 0 0 181 181 1 2
EPO CSF2 0 0 883 883 1 1
EPO IL12RB1 0 600 57 606 1 1
EPO EFNB3 0 0 322 322 1 1
EPO ACKR1 0 0 113 211 1 1
EPO CD48 0 0 235 236 1 1
EPO AKT1 0 0 664 673 1 2
EPO TGFB2 0 0 217 217 1 1
EPO PPARG 0 0 363 363 1 2
EPO CD2 0 0 170 169 1 1
EPO CDKN1B 0 0 174 175 1 2
EPO STAT5B 0 900 797 979 1 1
EPO RBX1 0 0 247 246 1 1
EPO PIK3C2A 0 0 170 169 1 1
EPO TSC2 0 0 186 186 1 2
EPO TGFB1 0 0 339 371 1 2
EPO GLUL 0 0 167 173 1 1
EPO ADORA2B 0 0 246 245 1 1
EPO BNIP3L 0 0 261 261 1 2
EPO MGAT5 0 0 76 175 1 1
EPO PF4 0 0 342 342 1 1
EPO ANPEP 0 0 298 298 1 1
EPO KDR 0 0 560 567 1 2
EPO JAK1 0 600 556 819 1 2
EPO CUBN 0 0 150 177 1 1
EPO RPL11 0 0 174 194 1 1
EPO TCHP 0 0 307 307 1 1
EPO PPBP 0 0 234 234 1 1
EPO SLC18A1 0 0 0 190 1 1
EPO DCX 0 0 244 245 1 1
EPO NRG1 0 0 147 173 1 2
EPO FGA 0 0 47 193 1 1
EPO EPB41 0 0 315 315 1 1
EPO FOXP3 0 0 234 234 1 2
EPO HMOX1 0 0 566 566 1 2
EPO PTPN6 0 900 219 918 1 1
EPO STAT6 0 0 247 371 1 1
EPO EIF2AK3 0 0 235 235 1 2
EPO SERPINB7 0 0 321 321 1 1
EPO HNF4A 0 0 244 243 1 1
EPO A2M 0 0 170 169 1 1
EPO TXNDC9 0 0 167 167 1 1
EPO VHL 0 0 610 628 1 2
EPO SIM1 0 0 74 215 1 1
EPO LDB2 0 0 264 270 1 1
EPO FLT1 0 0 456 456 1 1
EPO TLR3 0 0 155 154 1 2
EPO IL19 0 0 171 172 1 1
EPO RPE65 0 0 230 234 1 1
EPO ALAS2 0 0 588 591 1 1
EPO MIF 0 0 204 204 1 2
EPO LGALS3 0 0 181 181 1 2
EPO CDC42 0 0 193 193 1 2
EPO TIMM44 0 0 304 304 1 1
EPO SP2 0 0 46 252 1 1
EPO F2 0 0 454 530 1 1
EPO EPHB3 0 0 295 295 1 1
EPO TRIM58 0 0 124 167 1 1
EPO C1QBP 0 0 67 167 1 1
EPO DKK1 0 0 134 152 1 1
EPO SRC 0 0 469 469 1 2
EPO ADA 0 0 218 218 1 1
EPO HP 0 0 501 501 1 1
EPO PODXL 0 0 161 161 1 1
EPO APOE 0 0 284 284 1 2
EPO IL11RA 0 600 0 600 1 1
EPO SLC2A4 0 0 164 163 1 1
EPO KDM6A 0 0 66 164 1 1
EPO LIFR 0 600 161 650 1 1
EPO OXT 0 0 166 165 1 1
EPO FOXO3 0 0 390 390 1 2
EPO IL36B 0 0 0 179 1 1
EPO MB 0 0 456 456 1 2
EPO CD47 0 0 261 273 1 2
EPO BGLAP 0 0 260 289 1 1
EPO TNFSF11 0 0 220 220 1 2
EPO ADM 0 0 458 457 1 2
EPO GUSB 0 0 134 164 1 1
EPO EPHA3 0 0 292 292 1 1
EPO SOCS2 0 0 341 356 1 1
EPO SST 0 0 264 264 1 1
EPO CDKN2A 0 0 244 243 1 2
EPO TTR 0 0 391 390 1 1
EPO GSK3B 0 0 324 393 1 2
EPO ITGAX 0 0 193 203 1 1
EPO S100B 0 0 391 390 1 1
EPO SLC11A1 0 0 164 169 1 1
EPO FGF8 0 0 60 314 1 1
EPO GPX8 0 0 0 256 1 1
EPO CRLF3 0 0 471 482 1 1
EPO EPB42 0 0 170 169 1 1
EPO WNT2 0 0 124 266 1 1
EPO NTF3 0 0 324 367 1 1
EPO USF2 273 0 120 338 1 1
EPO EPHB2 0 0 390 390 1 2
EPO HPX 0 0 265 265 1 1
EPO GHR 0 600 308 711 1 1
EPO HCK 0 0 155 154 1 1
EPO PIK3CD 0 600 66 610 1 1
EPO IL13RA1 0 600 0 600 1 1
EPO FGF9 0 0 146 367 1 1
EPO CEBPB 0 0 181 181 1 2
EPO DHFR 0 0 166 181 1 1
EPO SLC4A1 0 0 226 307 1 1
EPO SLCO1C1 0 0 0 212 1 1
EPO FGF11 0 0 0 302 1 1
EPO AHSG 0 0 160 310 1 1
EPO CSF1 0 0 469 469 1 1
EPO HDAC1 0 0 157 156 1 2
EPO ACO1 0 0 427 487 1 1
EPO ENSG00000160201 0 0 166 165 1 1
EPO CXCL1 0 0 202 216 1 2
EPO EGLN1 0 0 665 669 1 1
EPO MMP14 0 0 160 171 1 1
EPO NLRP3 0 0 159 158 1 2
EPO REL 0 0 167 167 1 2
EPO FIGF 0 0 215 215 1 1
EPO AFP 0 0 323 392 1 2
EPO ERBB3 0 0 180 179 1 1
EPO CASP3 0 0 560 590 1 2
EPO NQO1 0 0 201 206 1 2
EPO F3 0 0 455 455 1 1
EPO CCL11 0 0 162 161 1 1
EPO PTGS2 0 0 341 354 1 2
EPO FGF19 0 0 0 302 1 1
EPO EPHA5 0 0 183 183 1 1
EPO TGM6 0 0 507 507 1 1
EPO IHH 0 0 103 164 1 1
EPO ACE 0 0 683 683 1 1
EPO FGF22 0 0 0 302 1 1
EPO ANG 0 0 267 283 1 2
EPO IL13 0 0 319 319 1 2
EPO REN 0 0 681 681 1 1
EPO CD28 0 0 209 209 1 1
EPO CD5 0 0 206 206 1 1
EPO CYBB 0 0 248 248 1 2
EPO VEGFC 0 0 263 286 1 1
EPO GDF11 0 0 273 273 1 1
EPO PTS 0 0 203 203 1 1
EPO MAPT 0 0 160 189 1 2
EPO BECN1 0 0 201 201 1 2
EPO MAOB 0 0 113 153 1 1
EPO THBS1 0 0 274 274 1 1
EPO ABCB1 0 0 138 170 1 2
EPO SDC1 0 0 124 314 1 1
EPO GYS1 0 0 74 150 1 1
EPO IL2 0 0 556 556 1 1
EPO LRP1 0 0 167 167 1 1
EPO SERPINA7 0 0 57 255 1 1
EPO SFRP2 0 0 120 156 1 1
EPO FLT4 0 0 254 254 1 1
EPO DUSP1 0 0 138 157 1 1
EPO FGF23 0 0 518 518 1 1
EPO SLC5A2 0 0 419 418 1 1
EPO LRP2 0 0 215 215 1 1
EPO PMAIP1 0 0 180 179 1 2
EPO PIK3CB 0 600 64 609 1 1
EPO SLC25A28 0 0 166 393 1 1
EPO TLR2 0 0 243 242 1 2
EPO AMH 0 0 72 298 1 1
EPO PICK1 0 0 112 162 1 1
EPO MET 0 0 283 300 1 2
EPO CPOX 0 0 115 168 1 1
EPO ENSG00000251246 0 0 162 161 1 1
EPO CD86 0 0 183 188 1 1
EPO SLC40A1 0 0 463 475 1 1
EPO PGF 0 0 470 470 1 1
EPO VHLL 0 0 124 165 1 1
EPO FASLG 0 0 293 293 1 1
EPO FOS 0 0 324 323 1 2
EPO THRB 0 0 61 165 1 1
EPO CA1 0 0 175 175 1 1
EPO SOCS3 0 900 392 936 1 1
EPO U2AFBP 0 0 166 165 1 1
EPO MATK 0 0 391 390 1 1
EPO AQP4 0 0 294 294 1 1
EPO ANGPTL4 0 0 181 200 1 1
EPO STAT5A 0 900 710 970 1 1
EPO GAB1 0 900 124 909 1 1
EPO TCEB1 0 0 370 370 1 1
EPO LMO2 0 0 324 335 1 1
EPO MSTN 0 0 217 217 1 1
EPO CRKL 0 900 321 929 1 1
EPO IFNL3 0 0 314 313 1 1
EPO DDAH1 0 0 193 193 1 1
EPO PTPN11 0 0 340 340 1 1
EPO FGF20 0 0 45 253 1 1
EPO NRAS 0 900 167 915 1 1
EPO HSPA5 0 0 171 171 1 2
EPO FTH1 0 0 217 224 1 1
EPO EPAS1 0 900 556 965 1 2
EPO FOXO1 0 0 260 260 1 2
EPO RPS14 0 0 181 198 1 1
EPO KRAS 0 900 175 926 1 2
EPO CD3E 0 0 175 181 1 1
EPO SOD2 0 0 184 196 1 2
EPO IFNGR1 0 600 150 645 1 1
EPO JMJD6 0 0 157 156 1 1
EPO PTH 0 0 710 710 1 1
EPO GPX2 0 0 0 165 1 1
EPO FOXD1 0 0 252 252 1 1
EPO RARA 0 0 134 157 1 2
EPO RARS 0 0 362 387 1 1
EPO RNLS 0 0 181 181 1 1
EPO GPX1 0 0 139 253 1 1
EPO CASR 0 0 170 169 1 2
EPO VTN 0 0 167 201 1 1
EPO FN1 0 0 469 470 1 2
EPO PCBP1 0 0 243 242 1 1
EPO C3 0 0 194 194 1 2
EPO IL5RA 0 600 72 612 1 1
EPO RPL5 0 0 141 178 1 1
EPO PRKCA 0 0 182 181 1 1
EPO ELANE 0 0 162 161 1 1
EPO THPO 0 800 898 979 1 1
EPO NCAM1 0 0 279 279 1 1
EPO SETD2 0 0 152 151 1 1
EPO TIMP2 0 0 180 179 1 1
EPO UBC 0 0 154 183 1 2
EPO MCAM 0 0 226 225 1 1
EPO LDB1 0 0 281 289 1 1
EPO ADAM17 0 0 128 151 1 1
EPO HMOX2 0 0 210 238 1 1
EPO EFNA2 0 0 155 174 1 1
EPO TGFBR1 0 0 134 211 1 1
EPO MST1R 0 0 113 274 1 1
EPO SOCS6 0 0 245 244 1 1
EPO IL22RA1 0 600 0 600 1 1
EPO ZFPM1 0 0 404 415 1 1
EPO TERT 0 0 193 213 1 2
EPO HSPB2 0 0 156 155 1 1
EPO TET2 0 0 347 347 1 2
EPO VAV1 0 600 242 684 1 1
EPO HSPB1 0 0 163 169 1 2
EPO XBP1 0 0 118 154 1 2
EPO GYPA 0 0 681 681 1 1
EPO SOX6 0 0 195 195 1 1
EPO STAT2 0 0 218 356 1 1
EPO HEMGN 0 0 140 163 1 1
EPO APOA5 0 0 0 152 1 1
EPO ATP4A 0 0 335 335 1 1
EPO PRKAG2 0 0 49 150 1 1
EPO F9 0 0 427 456 1 1
EPO ELN 0 0 243 242 1 1
EPO PTPN1 0 0 232 231 1 1
EPO MPL 0 600 814 942 1 1
EPO WNT3A 0 0 203 212 1 2
EPO LGR5 0 0 85 151 1 1
EPO ITGB3 0 0 310 309 1 1
EPO SYP 0 0 215 228 1 1
EPO BACE1 0 0 134 157 1 2
EPO SMAD7 0 0 202 202 1 1
EPO ITGAM 0 0 414 421 1 1
EPO GATA2 0 0 517 527 1 1
EPO ESR1 0 0 321 321 1 2
EPO IFNB1 0 0 379 379 1 1
EPO HMGB1 0 0 224 224 1 2
EPO LYN 0 900 323 929 1 1
EPO COPS5 0 900 60 901 1 1
EPO PCBP3 0 0 74 150 1 1
EPO CTF1 0 0 269 269 1 1
EPO SPI1 0 0 414 418 1 1
EPO NOX1 0 0 212 212 1 1
EPO ICAM4 0 0 226 225 1 1
EPO PRL 0 800 530 901 1 1
EPO ERVW-1 0 0 418 418 1 1
EPO MCL1 0 0 260 260 1 2
EPO SIRT1 0 0 377 377 1 2
EPO IL10RB 0 600 0 600 1 1
EPO TIMP3 0 0 123 154 1 1
EPO FBXL5 0 0 194 195 1 1
EPO MAPK14 0 900 204 922 1 2
EPO CSF3R 0 600 414 755 1 1
EPO ABCB7 0 0 160 177 1 1
EPO IL21R 0 600 0 600 1 1
EPO MGEA5 0 0 232 231 1 1
EPO RPS24 0 0 158 176 1 1
EPO FCGR2A 0 0 172 177 1 1
EPO SARNP 0 0 297 297 1 1
EPO NGFR 0 0 203 203 1 1
EPO WT1 0 0 266 266 1 1
EPO LDHA 0 0 418 435 1 2
EPO TCF4 0 0 120 159 1 1
EPO BMP4 0 0 405 418 1 1
EPO LEP 0 800 648 928 1 1
EPO KIT 0 900 693 968 1 2
EPO NFKBIA 0 0 210 210 1 2
EPO COMMD3-BMI1 0 0 150 165 1 1
EPO HFE 0 0 518 518 1 1
EPO ANP32D 0 0 178 177 1 1
EPO ADAMTS13 0 0 171 171 1 1
EPO SLC39A14 0 0 170 178 1 1
EPO SLC2A14 0 0 325 326 1 1
EPO TXN2 0 0 294 294 1 1
EPO VEGFA 0 0 803 807 1 2
EPO SERPINF2 0 0 142 227 1 1
EPO PTEN 0 0 323 324 1 2
EPO MAEA 0 0 181 182 1 1
EPO FTL 0 0 151 166 1 1
EPO MBP 0 0 362 389 1 2
EPO BMPR1A 0 0 141 186 1 1
EPO EFNB2 417 0 463 681 1 1
EPO IL10 0 0 576 576 1 2
EPO SNAI1 0 0 181 181 1 1
EPO HBB 0 0 468 468 1 1
EPO B4GALT1 0 0 81 173 1 1
EPO GFAP 0 0 324 342 1 2
EPO RBPJ 0 0 147 165 1 1
EPO NAMPT 0 0 147 165 1 2
EPO FLT3 0 0 602 626 1 2
EPO TMEM183A 0 0 108 263 1 1
EPO SELE 0 0 325 325 1 1
EPO TJP1 0 0 240 239 1 1
EPO DMD 0 0 120 175 1 2
EPO EGLN2 0 0 601 606 1 1
EPO TAC1 0 0 257 256 1 1
EPO ACTG1 0 0 147 172 1 1
EPO DLG4 0 0 134 205 1 2
EPO IKZF1 0 0 194 194 1 1
EPO GDF15 0 0 505 516 1 1
EPO EPHA6 0 0 114 150 1 1
EPO G6PD 0 0 230 229 1 1
EPO RET 0 0 269 269 1 1
EPO FGF12 0 0 0 290 1 1
EPO ENG 0 0 391 390 1 2
EPO CCL3 0 0 294 294 1 1
EPO FCGR3B 0 0 260 260 1 1
EPO IDH2 0 0 244 243 1 1
EPO SERPINC1 0 0 405 448 1 1
EPO IGF2 0 0 402 430 1 1
EPO CYGB 0 0 710 710 1 1
EPO ITGA2B 0 0 519 522 1 1
EPO NTF4 0 0 241 270 1 1
EPO EZR 0 0 165 165 1 1
EPO SMAD5 0 0 202 202 1 1
EPO SHC1 0 900 459 943 1 1
EPO THBD 0 0 277 277 1 1
EPO ATM 0 0 181 181 1 2
EPO CSF3 0 800 848 968 1 1
EPO ANKS1A 0 0 295 295 1 1
EPO SERPINA4 0 0 87 214 1 1
EPO RAF1 0 0 180 179 1 2
EPO FGF7 0 0 283 357 1 1
EPO TLX1 0 0 74 185 1 1
EPO CUL2 0 0 390 390 1 1
EPO HK2 0 0 181 181 1 2
EPO EDN3 0 0 146 165 1 1
EPO DDIT3 0 0 150 173 1 2
EPO WNT4 0 0 138 156 1 1
EPO GH2 0 800 252 844 1 1
EPO GIG25 0 0 90 151 1 1
EPO LINGO1 0 0 143 201 1 1
EPO TNFRSF11B 0 0 205 205 1 1
EPO MDM2 0 0 222 222 1 2
EPO TP53 0 0 496 500 1 2
EPO LCN2 0 0 370 370 1 1
EPO TGM2 0 0 143 162 1 2
EPO IL20RA 0 600 0 600 1 1
EPO HMBS 0 0 155 154 1 1
EPO C15orf41 0 0 143 161 1 1
EPO HOXB4 0 0 233 232 1 1
EPO SLC2A1 0 0 559 559 1 2
EPO CDK4 0 0 180 179 1 2
EPO EGFR 0 600 410 753 1 2
EPO FES 0 0 180 179 1 1
EPO MYD88 0 0 172 173 1 2
EPO ADORA3 0 0 261 261 1 1
EPO CYBRD1 0 0 458 461 1 1
EPO PCSK5 0 0 122 213 1 1
EPO TCF21 0 0 170 169 1 1
EPO CLCNKB 0 0 306 306 1 1
EPO MMP15 0 0 0 188 1 1
EPO GLRX5 0 0 123 212 1 1
EPO GATA3 0 0 183 188 1 1
EPO SERPINA11 0 0 0 183 1 1
EPO CD55 0 0 256 256 1 1
EPO TGFA 0 0 361 361 1 1
EPO PTN 0 0 193 193 1 1
EPO SEMA3B 0 0 166 165 1 1
EPO GDNF 0 0 469 496 1 2
EPO STAT3 0 0 595 603 1 2
EPO RBMS1 0 0 183 183 1 1
EPO EZH2 0 0 243 242 1 2
EPO IFNA2 0 0 294 294 1 1
EPO MST1 0 0 151 171 1 2
EPO DDAH2 0 0 195 195 1 1
EPO HBEGF 0 0 181 181 1 1
EPO JAK2 0 900 823 983 1 2
EPO GHRL 0 0 282 282 1 1
EPO CDH2 0 0 201 201 1 1
EPO PTX3 0 0 161 161 1 1
EPO APAF1 0 0 194 194 1 2
EPO SLC5A1 0 0 150 168 1 1
EPO RBM3 0 0 68 162 1 1
EPO CYBA 0 0 152 151 1 1
EPO IL20RB 0 600 0 600 1 1
EPO VGF 0 0 113 153 1 1
EPO RICTOR 0 0 149 168 1 2
EPO NOG 0 0 227 226 1 1
EPO MAP2 0 0 214 214 1 2
EPO GPX7 0 0 0 286 1 1
EPO MX1 0 0 181 181 1 1
EPO APOH 0 0 76 161 1 1
EPO SEMA6A 0 0 157 156 1 1
EPO EGLN3 0 0 557 569 1 1
EPO ADORA1 0 0 297 297 1 1
EPO CEACAM5 0 0 235 235 1 1
EPO GAB2 0 0 246 245 1 1
EPO IL27RA 0 600 0 600 1 1
EPO TOP1 0 0 162 161 1 1
EPO PIK3CA 0 600 129 636 1 2
EPO SERPINA5 0 0 82 160 1 1
EPO IL2RA 0 600 184 659 1 1
EPO MMP17 0 0 0 189 1 1
EPO EFNA4 0 0 193 193 1 1
EPO ACP5 0 0 142 184 1 1
EPO PPIG 0 0 252 252 1 1
EPO SLC1A3 0 0 166 166 1 1
EPO IL15 0 0 374 374 1 1
EPO PDK1 0 0 324 323 1 2
EPO MYC 0 0 455 455 1 2
EPO RPL35A 0 0 134 196 1 1
EPO DIRC2 0 0 204 253 1 1
EPO RPS26 0 0 139 161 1 1
EPO IFNA1 0 0 459 459 1 1
EPO WNT5A 0 0 167 176 1 2
EPO ILK 0 0 146 168 1 1
EPO IL18 0 0 335 344 1 2
EPO STEAP3 0 0 220 245 1 1
EPO NR2C1 0 0 92 155 1 1
EPO MPP3 0 0 91 202 1 1
EPO IGF1R 0 0 253 252 1 2
EPO SDHC 0 0 265 265 1 1
EPO PPARGC1A 0 0 304 304 1 2
EPO SDHAF2 0 0 155 154 1 1
EPO FGF10 0 0 54 221 1 1
EPO CSH2 0 800 217 836 1 1
EPO PI3 0 0 160 159 1 2
EPO NFE2L2 0 0 292 292 1 2
EPO AKT2 0 0 155 161 1 2
EPO SLC30A10 0 0 156 174 1 1
EPO RPS19 0 0 257 274 1 1
EPO PDGFB 0 0 325 325 1 2
EPO PFKM 0 0 95 181 1 1
EPO CD80 0 0 170 169 1 2
EPO FURIN 0 0 217 224 1 1
EPO RPS17 0 0 134 167 1 1
EPO NPY 0 0 241 240 1 1
EPO OSM 0 0 341 341 1 1
EPO TCF3 0 0 180 179 1 1
EPO AQP1 0 0 230 231 1 1
EPO MAP2K1 0 0 244 243 1 1
EPO FUT4 0 0 298 298 1 1
EPO PPIF 0 0 154 169 1 1
EPO SMAD4 0 0 261 261 1 2
EPO SLC2A3 0 0 324 325 1 1
EPO PBK 0 0 0 175 1 1
EPO EIF5B 0 0 637 637 1 1
EPO HDAC5 0 0 86 182 1 1
EPO FXN 0 0 459 490 1 1
EPO SYNPO 0 0 155 154 1 1
EPO TFR2 0 0 676 682 1 1
EPO EFNA5 0 0 265 284 1 1
EPO DDX39A 0 0 430 430 1 1
EPO ANXA5 0 0 428 448 1 2
EPO NPPA 0 0 125 187 1 1
EPO OSMR 0 600 57 606 1 1
EPO FGF21 0 0 122 360 1 2
EPO RYR3 0 0 0 175 1 1
EPO AHSP 0 0 325 325 1 1
EPO SIRT2 0 0 232 231 1 2
EPO IL4R 0 600 107 627 1 1
EPO U2AF1L4 0 0 167 167 1 1
EPO PTGER1 0 0 179 179 1 1
EPO SDHB 0 0 170 169 1 1
EPO HAVCR1 0 0 290 334 1 1
EPO NFE2 0 0 391 403 1 1
EPO ACO2 0 0 175 197 1 1
EPO RYR2 0 0 0 250 1 1
EPO UROD 0 0 136 167 1 1
EPO PFKL 0 0 125 208 1 1
EPO CREBBP 0 900 260 928 1 1
EPO IFNG 0 0 505 513 1 2
EPO IL2RB 0 600 81 623 1 1
EPO GAST 0 0 181 181 1 1
EPO PLCG2 0 600 72 612 1 1
EPO FGF14 0 0 0 250 1 1
EPO EFNB1 0 0 370 370 1 1
EPO TGFB3 0 0 170 169 1 1
EPO CCL5 0 0 319 320 1 2
EPO CREB1 0 900 325 929 1 2
EPO TWSG1 0 0 325 372 1 1
EPO SMAD2 0 0 261 261 1 2
EPO TLR4 0 0 325 340 1 2
EPO IL9R 0 600 45 601 1 1
EPO GP9 0 0 127 209 1 1
EPO FGFR2 0 0 129 153 1 1
EPO SH2B3 0 900 416 939 1 1
EPO ENO1 0 0 260 260 1 1
EPO TRPC3 0 0 153 152 1 1
EPO GAPDH 0 0 465 471 1 2
EPO HAMP 0 0 845 845 1 1
EPO APOA1 0 0 233 301 1 1
EPO RAP1A 0 900 56 901 1 1
EPO ABL1 0 0 451 451 1 1
EPO NOS2 0 0 278 294 1 2
EPO CX3CL1 0 0 185 187 1 1
EPO MAP2K7 0 0 370 370 1 1
EPO KITLG 0 900 948 994 1 1
EPO SLC9A1 0 0 125 185 1 1
EPO UMOD 0 0 291 290 1 1
EPO MMP20 0 0 0 189 1 1
EPO RHCE 0 0 270 270 1 1
EPO ITGA4 0 0 171 171 1 1
EPO STAT4 0 0 143 376 1 1
EPO NPTN 0 0 707 707 1 1
EPO EPHA8 0 0 232 232 1 1
EPO CD7 0 0 194 194 1 1
EPO KLF6 0 0 69 170 1 1
EPO NFKB1 0 900 105 907 1 2
EPO DNMT3A 0 0 246 245 1 2
EPO SLC5A4 0 0 408 408 1 1
EPO TEC 0 900 0 902 1 1
EPO DNMT3B 0 0 103 152 1 1
EPO ALDOA 0 0 180 191 1 1
EPO RELA 0 0 145 169 1 2
EPO BCL2L1 0 0 562 565 1 2
EPO CCL4L1 0 0 183 183 1 1
EPO CTNNB1 0 0 341 350 1 2
EPO FCGR3A 0 0 261 261 1 1
EPO DMTN 0 0 144 176 1 1
EPO HRAS 0 900 260 930 1 2
EPO CDK2 0 0 193 193 1 2
EPO SOCS7 0 0 234 234 1 1
EPO APP 0 0 262 262 1 2
EPO HBA1 0 0 293 293 1 1
EPO SHMT2 0 0 289 288 1 1
EPO EPHA2 0 0 566 566 1 1
EPO EGR1 0 0 290 291 1 2
EPO RHO 0 0 181 210 1 2
EPO HBG2 0 0 249 351 1 1
EPO NEO1 0 0 150 172 1 1
EPO CXCR2 0 0 164 163 1 1
EPO WNT2B 0 0 95 178 1 1
EPO MYOM2 0 0 164 163 1 1
EPO TNFRSF1B 0 0 218 218 1 1
EPO SH2B2 0 0 134 156 1 1
EPO HIF1A 486 900 802 989 1 2
EPO EDN1 0 0 561 568 1 1
EPO CYP27B1 0 0 150 169 1 1
EPO SMAD9 0 0 142 195 1 1
EPO SIRT5 0 0 218 218 1 1
EPO HIF3A 0 900 322 929 1 1
EPO SP1 0 0 193 193 1 2
EPO IL1B 0 0 562 562 1 2
EPO DLX4 0 0 353 367 1 1
EPO ID1 0 0 157 156 1 1
EPO CXCL8 0 0 495 495 1 2
EPO RQCD1 0 0 90 333 1 1
EPO NDST3 0 0 0 187 1 1
EPO KLK3 0 0 184 183 1 1
EPO IL6R 0 600 193 663 1 1
EPO MPZ 0 0 150 174 1 1
EPO UCP2 0 0 193 193 1 2
EPO VAV2 0 900 0 900 1 1
EPO DOK2 244 0 0 243 1 1
EPO MPO 0 0 395 394 1 2
EPO IL3RA 0 600 211 670 1 1
EPO HBM 0 0 156 170 1 1
EPO MOG 0 0 184 199 1 1
EPO IL6 0 0 735 736 1 2
EPO STAT1 0 900 391 947 1 2
EPO SOCS5 0 0 256 256 1 1
EPO FOXO6 0 0 173 248 1 1
EPO P4HTM 0 0 229 228 1 1
EPO RPS6 0 0 180 179 1 2
EPO TNFRSF1A 0 0 377 377 1 1
EPO NPHS1 0 0 210 218 1 1
EPO THRA 0 0 184 214 1 1
EPO HFE2 0 0 556 576 1 1
EPO OCLN 0 0 240 239 1 1
EPO PLEK 0 0 174 173 1 1
EPO CD177 0 0 294 294 1 1
EPO FGF13 0 0 306 377 1 1
EPO CXCR4 0 0 470 497 1 2
EPO DOHH 0 0 66 166 1 1
EPO DNTTIP2 0 0 294 294 1 1
EPO MMP1 0 0 181 226 1 1
EPO NOTCH1 0 0 643 643 1 2
EPO ENTPD1 0 0 140 158 1 1
EPO CD40LG 0 0 166 165 1 1
EPO MTOR 0 0 459 461 1 2
EPO HNRNPLL 0 0 398 398 1 1
EPO GNE 0 0 125 187 1 1
EPO POTEF 0 0 150 186 1 1
EPO SAA1 0 0 170 169 1 1
EPO CD163 0 0 206 206 1 1
EPO PSMC6 0 0 195 195 1 1
EPO GSR 0 0 216 216 1 1
EPO IFNAR2 0 600 113 630 1 1
EPO RHOA 0 0 247 246 1 2
EPO PARP1 0 0 157 156 1 2
EPO AR 0 0 194 194 1 2
EPO ASXL1 0 0 325 325 1 1
EPO CSF2RA 0 0 298 298 1 1
EPO CDKN1A 0 0 230 229 1 2
EPO SFTPB 0 0 113 153 1 1
EPO SPP1 0 0 339 339 1 2
EPO BAX 0 0 180 179 1 2
EPO TIMP1 0 0 329 329 1 1
EPO IL36A 0 0 0 175 1 1
EPO FGF4 0 0 96 377 1 1
EPO CXCL12 0 0 558 558 1 2
EPO CRLF2 0 600 138 640 1 1
EPO CITED2 0 0 210 210 1 1
EPO TNNI3 0 0 194 194 1 1
EPO PTPRC 0 0 520 530 1 1
EPO BCR 0 0 134 173 1 2
EPO HBE1 0 0 470 508 1 1
EPO IGFBP2 0 0 150 174 1 1
EPO ADORA2A 0 0 261 261 1 1
EPO CEBPE 0 0 168 167 1 1
EPO ICAM1 0 0 405 425 1 2
EPO SLC46A1 0 0 209 218 1 1
EPO HBS1L 0 0 193 214 1 1
EPO SIRT7 0 0 234 234 1 2
EPO IL22 0 0 182 181 1 1
EPO CD24 0 0 152 151 1 2
EPO IL21 0 0 0 297 1 1
EPO HPGDS 0 0 210 210 1 1
EPO IL3 0 0 877 877 1 1
EPO HSP90AA1 0 0 294 294 1 2
EPO PSEN1 0 0 166 165 1 2
EPO ATF2 0 0 96 192 1 1
EPO CRP 0 0 710 710 1 2
EPO ACTN3 0 0 112 173 1 1
EPO SOX2 0 0 242 241 1 2
EPO ACSBG1 0 0 53 336 1 1
EPO EPHA7 0 0 234 234 1 1
EPO CEBPA 0 0 310 309 1 1
EPO BPIFB2 0 0 0 151 1 1
EPO CD40 0 0 195 195 1 2
EPO FGF1 0 0 293 293 1 1
EPO FUT8 0 0 113 153 1 1
EPO DNMT1 0 0 165 165 1 2
EPO SELP 0 0 344 343 1 1
EPO INS 0 0 681 684 1 2
EPO CLDN5 0 0 156 157 1 1
EPO GAS6 0 0 141 160 1 1
EPO ACTB 0 0 503 524 1 2
EPO NEFH 0 0 161 161 1 1
EPO FOXG1 0 0 89 151 1 1
EPO SERPINA12 0 0 0 159 1 1
EPO MSN 0 0 171 171 1 1
EPO C1orf186 0 0 261 261 1 1
EPO EPHA10 0 0 363 366 1 1
EPO ZNF185 0 0 305 305 1 1
EPO ENSG00000258555 0 0 156 155 1 1
EPO SIM2 0 0 97 273 1 1
EPO JUNB 0 0 67 161 1 1
EPO SLC11A2 0 0 520 531 1 1
EPO BNIP3 0 0 403 407 1 2
EPO FCGR2B 0 0 146 166 1 1
EPO KEAP1 0 0 228 233 1 2
EPO PAX5 0 0 138 156 1 1
EPO B2M 0 0 455 455 1 1
EPO MMP9 0 0 459 471 1 2
EPO MAPK3 0 0 468 477 1 2
EPO ANGPT1 0 0 504 513 1 1
EPO THY1 0 0 341 341 1 1
EPO PROM1 0 0 460 459 1 2
EPO SIRT3 0 0 235 235 1 2
EPO SLC16A3 0 0 195 195 1 1
EPO PLAT 0 0 310 309 1 1
EPO SNCA 0 0 210 210 1 2
EPO DNTT 0 0 381 403 1 1
EPO RTN4R 0 0 181 186 1 1
EPO CASP1 0 0 253 258 1 2
EPO TMPRSS6 0 0 594 605 1 1
EPO NOS1 0 0 292 307 1 1
EPO HSPA1A 0 0 137 180 1 1
EPO COL18A1 0 0 294 294 1 1
EPO AIF1 0 0 248 248 1 2
EPO ERBB4 0 0 150 179 1 1
EPO CAV1 0 0 156 155 1 2
EPO TNFSF10 0 0 183 183 1 2
EPO JAK3 0 600 507 814 1 1
EPO PIK3CG 0 600 150 645 1 1
EPO IL10RA 0 600 74 613 1 1
EPO CDH17 0 0 204 204 1 1
EPO DLL4 0 0 205 205 1 1
EPO NPPB 0 0 321 321 1 1
EPO BCL2L11 0 0 261 266 1 2
EPO KL 0 0 406 413 1 2
EPO SI 0 0 202 202 1 1
EPO SERPINA1 0 0 281 433 1 2
EPO ENSG00000173366 0 0 150 156 1 1
EPO SIGLEC1 0 0 154 153 1 1
EPO SLC16A4 0 0 173 173 1 1
EPO PLCG1 0 900 183 914 1 1
EPO HEPH 0 0 324 336 1 1
EPO JUN 0 900 400 937 1 2
EPO GP1BA 0 0 217 217 1 1
EPO TYK2 0 0 556 556 1 1
EPO PSMD1 0 0 0 150 1 1
EPO FYN 0 0 150 169 1 1
EPO GRB2 0 900 325 929 1 1
EPO ANK1 0 0 181 181 1 1
EPO JAG1 0 0 233 232 1 1
EPO GHRH 0 0 235 235 1 1
EPO LCK 0 0 333 339 1 1
EPO LTA 0 0 164 216 1 1
EPO SOD1 0 0 253 252 1 2
EPO IL36RN 0 0 0 177 1 1
EPO IL7R 0 600 249 686 1 1
EPO ARNT 0 900 710 970 1 2
EPO BMI1 0 0 148 163 1 1
EPO NCOA4 0 0 134 232 1 2
EPO CCR5 0 0 180 179 1 1
EPO FGF6 0 0 0 302 1 1
EPO SHH 0 0 291 303 1 2
EPO DLL1 0 0 165 165 1 1
EPO IGFBP3 0 0 260 260 1 2
EPO CALR 0 0 336 336 1 1
EPO UCHL1 0 0 126 192 1 2
EPO CD8A 0 0 455 455 1 1
EPO GAP43 0 0 181 181 1 1
EPO BMP6 0 0 408 412 1 1
EPO IRS2 0 900 292 926 1 1
EPO IL22RA2 0 600 0 600 1 1
EPO ANGPT2 0 0 464 465 1 1
EPO SLAMF1 0 0 324 325 1 1
EPO MMP2 0 0 382 382 1 2
EPO PTK2 0 0 170 169 1 2
EPO B4GALT4 0 0 87 226 1 1
EPO ADIPOQ 0 0 325 325 1 2
EPO BCL11A 0 0 369 400 1 1
EPO CBFA2T3 0 0 145 177 1 1
EPO HBG1 0 0 243 363 1 1
EPO ARG1 0 0 233 232 1 2
EPO GRB7 0 0 66 187 1 1
EPO MAPK8 0 900 218 918 1 2
EPO CALCA 0 0 293 293 1 1
EPO FGF18 0 0 45 215 1 1
EPO RAPGEF1 0 600 448 770 1 1
EPO ENO2 0 0 335 335 1 1
EPO IL1F10 0 0 0 177 1 1
EPO GPX4 0 0 97 245 1 2
EPO HIST2H3PS2 0 0 234 234 1 1
EPO HBZ 0 0 235 306 1 1
EPO SESN2 0 0 244 243 1 2
EPO CTGF 0 0 278 283 1 1
EPO PRNP 0 0 70 212 1 2
EPO FKBP1A 0 0 143 159 1 2
EPO NR3C1 0 0 317 317 1 1
EPO IL2RG 0 600 274 702 1 1
EPO PDGFA 0 0 122 164 1 1
EPO CISH 0 0 421 420 1 1
EPO NDST4 0 0 0 187 1 1
EPO GATA4 0 0 310 330 1 2
EPO LIF 0 0 459 459 1 2
EPO ACVR1 0 0 173 179 1 1
EPO HSPA4 0 0 314 313 1 1
EPO PROCR 0 0 170 169 1 1
EPO IL12RB2 0 600 0 609 1 1
EPO RDX 0 0 180 179 1 1
EPO PIK3R1 0 600 142 642 1 1
EPO CX3CR1 0 0 164 163 1 1
EPO DICER1 0 0 162 161 1 1
EPO CCR2 0 0 193 193 1 2
EPO TIE1 0 0 230 229 1 1
EPO HSPB3 0 0 181 181 1 1
EPO RPTOR 0 0 167 167 1 2
EPO NES 0 0 324 323 1 2
EPO TRPC6 0 0 204 204 1 1
EPO NGB 0 0 370 382 1 1
EPO LPL 0 0 142 168 1 1
EPO TEK 0 0 459 466 1 1
EPO ACHE 0 0 303 303 1 2
EPO CXCL9 0 0 160 159 1 1
EPO HIF1AN 0 0 464 463 1 1
EPO PPARA 0 0 280 280 1 2
EPO GNAS 0 0 241 240 1 1
EPO POMC 0 0 335 335 1 1
EPO GFI1B 0 0 283 282 1 1
EPO NANOG 0 0 232 231 1 2
EPO SLC1A2 0 0 193 193 1 1
EPO HK1 0 0 157 156 1 1
EPO CASP9 0 0 322 352 1 2
EPO IL13RA2 0 600 0 608 1 1
EPO FAM210B 0 0 57 402 1 1
EPO CYCS 0 0 424 424 1 2
EPO NRP1 0 0 210 210 1 1
EPO RGMA 0 0 324 323 1 1
EPO CD59 0 0 234 234 1 1
EPO BMP2 0 0 320 324 1 1
EPO FIP1L1 0 0 142 181 1 1
EPO EGF 0 0 540 540 1 2
EPO AKR1B1 0 0 234 234 1 1
EPO HNF1A 0 0 181 181 1 1
EPO IGFBP1 0 0 288 372 1 1
EPO SBDS 0 0 145 203 1 1
EPO SENP1 0 0 212 212 1 1
EPO IL17A 0 0 324 323 1 2
EPO ETS1 0 0 233 232 1 1
EPO FCGRT 0 0 393 430 1 1
EPO PDGFRB 0 600 339 724 1 2
EPO F7 0 0 320 344 1 1
EPO EP300 111 900 523 953 1 2
EPO SIRPA 0 0 181 181 1 1
EPO IL4 0 0 609 609 1 1
EPO IL9 0 0 390 390 1 1
EPO ELMO1 0 0 293 293 1 1
EPO BPGM 0 0 242 241 1 1
EPO SMAD3 0 0 251 250 1 2
EPO SPARC 0 0 151 150 1 2
EPO ANXA8 0 0 201 201 1 1
EPO DOK1 0 0 136 175 1 1
EPO HBQ1 0 0 157 156 1 1
EPO CNTF 0 800 424 882 1 1
EPO ANKRD54 0 0 308 344 1 1
EPO SERPINF1 0 0 147 165 1 1
EPO AMBP 0 0 136 236 1 1
EPO LEPR 0 600 351 729 1 1
EPO SLC25A37 0 0 263 309 1 1
EPO CREB3L3 0 0 306 308 1 1
EPO CNTFR 0 600 0 600 1 1
EPO KNG1 0 0 358 358 1 1
EPO GYPC 0 0 155 154 1 1
EPO CCL2 0 0 459 459 1 2
EPO ALB 0 0 753 782 1 2
EPO CASP8 0 0 262 266 1 2
EPO CD68 0 0 261 261 1 2
EPO ITGB1 0 0 218 235 1 1
EPO PGK1 0 0 393 392 1 2
EPO MME 0 0 243 242 1 1
EPO PIK3R5 0 600 0 600 1 1
EPO GATA1 0 0 682 711 1 1
EPO DPP4 0 0 322 321 1 1
EPO PLEKHH2 0 0 310 309 1 1
EPO BCHE 0 0 207 207 1 1
EPO CSH1 0 800 204 833 1 1
EPO CSN2 0 0 251 250 1 1
EPO CCL4 0 0 216 216 1 1
EPO AVP 0 0 310 309 1 1
EPO TFPI 0 0 149 188 1 1
EPO IL1A 0 0 395 394 1 1
EPO AQP2 0 0 167 167 1 1
EPO PRAF2 0 0 194 199 1 1
EPO ACVR2B 0 0 134 172 1 1
EPO CRYGC 0 0 181 181 1 1
EPO WNT1 0 0 210 210 1 2
EPO CYP3A4 0 0 204 204 1 1
EPO FECH 0 0 335 363 1 1
EPO AGER 0 0 233 232 1 2
EPO EPHA4 0 0 407 407 1 1
EPO SIRT6 0 0 234 234 1 2
EPO CP 0 0 335 339 1 1
EPO NEFL 0 0 157 156 1 1
EPO CDK6 0 0 141 156 1 2
EPO PLG 0 0 502 514 1 1
EPO PDGFRA 0 600 203 667 1 1
EPO FGF17 0 0 0 290 1 1
EPO CDH1 0 0 294 294 1 2
EPO SCARA5 0 0 108 152 1 1
EPO RYR1 0 0 50 182 1 2
EPO IDH1 0 0 264 264 1 1
EPO CD33 0 0 406 406 1 1
EPO BMP7 0 0 271 272 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0005125 Molecular Function cytokine activity enables IBA
GO:0005125 Molecular Function cytokine activity enables IDA
GO:0005128 Molecular Function erythropoietin receptor binding enables IBA
GO:0005128 Molecular Function erythropoietin receptor binding enables IMP
GO:0005179 Molecular Function hormone activity enables IEA
GO:0005515 Molecular Function protein binding enables IPI
GO:0030295 Molecular Function protein kinase activator activity enables IBA
GO:0006953 Biological Process acute-phase response involved_in IEA
GO:0008015 Biological Process blood circulation involved_in NAS
GO:0071474 Biological Process cellular hyperosmotic response involved_in IDA
GO:0007566 Biological Process embryo implantation involved_in IEA
GO:0030218 Biological Process erythrocyte differentiation involved_in IDA
GO:0030218 Biological Process erythrocyte differentiation involved_in IMP
GO:0043249 Biological Process erythrocyte maturation involved_in IEA
GO:0038162 Biological Process erythropoietin-mediated signaling pathway involved_in IBA
GO:0038162 Biological Process erythropoietin-mediated signaling pathway involved_in IMP
GO:0042541 Biological Process hemoglobin biosynthetic process involved_in IEA
GO:0033028 Biological Process myeloid cell apoptotic process involved_in IEA
GO:0010523 Biological Process negative regulation of calcium ion transport into cytosol involved_in IDA
GO:2001258 Biological Process negative regulation of cation channel activity involved_in IDA
GO:1902251 Biological Process negative regulation of erythrocyte apoptotic process involved_in IDA
GO:1902219 Biological Process negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress involved_in IDA
GO:0000122 Biological Process negative regulation of transcription by RNA polymerase II involved_in IMP
GO:0045893 Biological Process positive regulation of DNA-templated transcription involved_in IDA
GO:0070374 Biological Process positive regulation of ERK1 and ERK2 cascade involved_in IEA
GO:0046579 Biological Process positive regulation of Ras protein signal transduction involved_in IBA
GO:0046579 Biological Process positive regulation of Ras protein signal transduction involved_in IDA
GO:0042104 Biological Process positive regulation of activated T cell proliferation involved_in IEA
GO:0008284 Biological Process positive regulation of cell population proliferation involved_in IBA
GO:0008284 Biological Process positive regulation of cell population proliferation involved_in IDA
GO:0045666 Biological Process positive regulation of neuron differentiation involved_in IEA
GO:0010976 Biological Process positive regulation of neuron projection development involved_in IEA
GO:0042531 Biological Process positive regulation of tyrosine phosphorylation of STAT protein involved_in IDA
GO:0048678 Biological Process response to axon injury involved_in IEA
GO:0071548 Biological Process response to dexamethasone involved_in IEA
GO:0051602 Biological Process response to electrical stimulus involved_in IEA
GO:0043627 Biological Process response to estrogen involved_in IEA
GO:0055093 Biological Process response to hyperoxia involved_in IEA
GO:0001666 Biological Process response to hypoxia involved_in IEA
GO:0070555 Biological Process response to interleukin-1 involved_in IEA
GO:0032496 Biological Process response to lipopolysaccharide involved_in IEA
GO:0009651 Biological Process response to salt stress involved_in IEA
GO:0033574 Biological Process response to testosterone involved_in IEA
GO:0033189 Biological Process response to vitamin A involved_in IEA
GO:0007165 Biological Process signal transduction involved_in NAS
GO:0044297 Cellular Component cell body located_in IEA
GO:0009986 Cellular Component cell surface located_in IDA
GO:0005576 Cellular Component extracellular region located_in TAS
GO:0005615 Cellular Component extracellular space is_active_in IBA
GO:0005615 Cellular Component extracellular space located_in IDA
Pathways
Name DB ID
Regulation of gene expression by Hypoxia-inducible Factor Reactome R-HSA-1234158
Cellular response to hypoxia Reactome R-HSA-1234174
Signal Transduction Reactome R-HSA-162582
Cellular responses to stress Reactome R-HSA-2262752
Cellular responses to stimuli Reactome R-HSA-8953897
Signaling by Erythropoietin Reactome R-HSA-9006335
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) Reactome R-HSA-9027276
Erythropoietin activates Phospholipase C gamma (PLCG) Reactome R-HSA-9027277
Erythropoietin activates STAT5 Reactome R-HSA-9027283
Erythropoietin activates RAS Reactome R-HSA-9027284
Hematopoietic stem cell differentiation (WP2849) WikiPathways WP2849_r117150
Photodynamic therapy-induced HIF-1 survival signaling (WP3614) WikiPathways WP3614_r106542
Overview of proinflammatory and profibrotic mediators (WP5095) WikiPathways WP5095_r120801
Focal adhesion: PI3K-Akt-mTOR-signaling pathway (WP3932) WikiPathways WP3932_r124527
Pluripotent stem cell differentiation pathway (WP2848) WikiPathways WP2848_r120814
Markers of kidney cell lineage (WP5236) WikiPathways WP5236_r124473
EPO receptor signaling (WP581) WikiPathways WP581_r117099
PI3K-Akt signaling pathway (WP4172) WikiPathways WP4172_r122580
Transcripts
Accession Version MolecularType Name NCBI Comments
NM_000799 4 mRNA None NC_000007 Reference