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ERN1

endoplasmic reticulum to nucleus signaling 1
General Information
Name endoplasmic reticulum to nucleus signaling 1
Alias
  • serine/threonine-protein kinase/endoribonuclease IRE1
  • ER to nucleus signalling 1
  • inositol-requiring 1
  • inositol-requiring enzyme 1
  • inositol-requiring protein 1
  • ire1-alpha
  • protein kinase/endoribonuclease
Gene_family Endoribonucleases
organism Homo sapiens
entrez_id 2081
location 17q23.3
transcript_count 1
exon_count 22
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez This gene encodes the transmembrane protein kinase inositol-requiring enzyme 1. The encoded protein contains two functional catalytic domains, a serine/threonine-protein kinase domain and an endoribonuclease domain. This protein functions as a sensor of unfolded proteins in the endoplasmic reticulum (ER) and triggers an intracellular signaling pathway termed the unfolded protein response (UPR). The UPR is an ER stress response that is conserved from yeast to mammals and activates genes involved in degrading misfolded proteins, regulating protein synthesis and activating molecular chaperones. This protein specifically mediates the splicing and activation of the stress response transcription factor X-box binding protein 1. [provided by RefSeq, Aug 2017]
    Stringdb Serine/threonine-protein kinase/endoribonuclease IRE1; Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto- activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis
    nextProt Serine/threonine-protein kinase and endoribonuclease that acts as a key sensor for the endoplasmic reticulum unfolded protein response (UPR) (PubMed:11779464, PubMed:11175748, PubMed:12637535, PubMed:9637683, PubMed:21317875, PubMed:28128204). In unstressed cells, the endoplasmic reticulum luminal domain is maintained in its inactive monomeric state by binding to the endoplasmic reticulum chaperone HSPA5/BiP (PubMed:21317875). Accumulation of misfolded proteins in the endoplasmic reticulum causes release of HSPA5/BiP, allowing the luminal domain to homodimerize, promoting autophosphorylation of the kinase domain and subsequent activation of the endoribonuclease activity (PubMed:21317875). The endoribonuclease activity is specific for XBP1 mRNA and excises 26 nucleotides from XBP1 mRNA (PubMed:11779464, PubMed:24508390, PubMed:21317875). The resulting spliced transcript of XBP1 encodes a transcriptional activator protein that up-regulates expression of UPR target genes (PubMed:11779464, PubMed:24508390, PubMed:21317875). Acts as an upstream signal for ER stress-induced GORASP2-mediated unconventional (ER/Golgi-independent) trafficking of CFTR to cell membrane by modulating the expression and localization of SEC16A (PubMed:21884936, PubMed:28067262).
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
ERN1 BioGRID CNPY3 GeneID BioGRID Proximity Label-MS
ERN1 BioGRID SEC61B GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-localization
ERN1 BioGRID HMGCS1 GeneID BioGRID Affinity Capture-MS
ERN1 BioGRID ATF6 GeneID BioGRID Affinity Capture-Western
ERN1 BioGRID RIPK2 GeneID BioGRID Affinity Capture-Western
ERN1 BioGRID ERN1 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Co-crystal Structure; Co-purification; Reconstituted Complex
ERN1 BioGRID CLEC12B GeneID BioGRID Affinity Capture-MS
ERN1 BioGRID TAFA2 GeneID BioGRID Affinity Capture-MS
ERN1 BioGRID ZNRF4 GeneID BioGRID Affinity Capture-MS
ERN1 BioGRID LSMEM2 GeneID BioGRID Affinity Capture-MS
ERN1 BioGRID SYT2 GeneID BioGRID Affinity Capture-MS
ERN1 BioGRID C3orf52 GeneID BioGRID Affinity Capture-MS
ERN1 BioGRID PCDHGB5 GeneID BioGRID Affinity Capture-MS
ERN1 BioGRID ASIC4 GeneID BioGRID Affinity Capture-MS
ERN1 BioGRID NTAQ1 GeneID BioGRID Affinity Capture-MS
ERN1 BioGRID ADIPOQ GeneID BioGRID Affinity Capture-MS
ERN1 BioGRID SLC6A1 GeneID BioGRID Affinity Capture-MS
ERN1 BioGRID HLA-DQA1 GeneID BioGRID Affinity Capture-MS
ERN1 BioGRID FCER1A GeneID BioGRID Affinity Capture-MS
ERN1 BioGRID APOC3 GeneID BioGRID Affinity Capture-MS
ERN1 BioGRID UBA5 GeneID BioGRID Phenotypic Suppression
ERN1 BioGRID P4HB GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
ERN1 BioGRID HSPA5 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
ERN1 BioGRID PDIA6 GeneID BioGRID Affinity Capture-Western
ERN1 BioGRID Marchf5 GeneID BioGRID Reconstituted Complex
ERN1 BioGRID MARCHF5 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
ERN1 BioGRID BCL2L11 GeneID BioGRID Affinity Capture-Western
ERN1 BioGRID VIRMA GeneID BioGRID Affinity Capture-RNA
ERN1 BioGRID SEC61A1 GeneID BioGRID Co-purification
ERN1 BioGRID SEC63 GeneID BioGRID Co-purification
ERN1 BioGRID NMI GeneID BioGRID Affinity Capture-Western; PCA
ERN1 BioGRID LYPD4 GeneID BioGRID Affinity Capture-MS
ERN1 BioGRID SCGB2A2 GeneID BioGRID Affinity Capture-MS
ERN1 BioGRID RIPK1 GeneID BioGRID Affinity Capture-Western
ERN1 BioGRID SYVN1 GeneID BioGRID Affinity Capture-Western
ERN1 BioGRID TRAF2 GeneID BioGRID Affinity Capture-Western; Co-localization
ERN1 BioGRID TP53 GeneID BioGRID Affinity Capture-Western
ERN1 BioGRID MAP3K5 GeneID BioGRID Affinity Capture-Western; Co-localization
ERN1 BioGRID MYC GeneID BioGRID Synthetic Lethality
ERN1 BioGRID FBXO11 GeneID BioGRID Affinity Capture-MS
ERN1 BioGRID OTUB1 GeneID BioGRID Affinity Capture-MS
ERN1 BioGRID FBXL21P GeneID BioGRID Affinity Capture-MS
ERN1 BioGRID STUB1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
ERN1 BioGRID UCHL1 GeneID BioGRID Affinity Capture-MS
ERN1 BioGRID RNF13 GeneID BioGRID Affinity Capture-Western
ERN1 BioGRID USP14 GeneID BioGRID Affinity Capture-Western; Two-hybrid
ERN1 BioGRID TRAF6 GeneID BioGRID Affinity Capture-Western
ERN1 BioGRID SRPK2 GeneID BioGRID Biochemical Activity
ERN1 BioGRID COPS5 GeneID BioGRID Affinity Capture-Western; Two-hybrid
ERN1 BioGRID DERL3 GeneID BioGRID Affinity Capture-Western
ERN1 BioGRID DERL1 GeneID BioGRID Affinity Capture-Western
ERN1 BioGRID SEL1L GeneID BioGRID Affinity Capture-Western
ERN1 Protein TAOK3 GeneID HPRD
ERN1 Protein COPS5 GeneID HPRD
ERN1 Protein ERN1 GeneID HPRD
ERN1 Protein MAP3K5 GeneID HPRD
ERN1 Protein TRAF2 GeneID HPRD
ERN1 Protein BAK1 GeneID HPRD
ERN1 Protein BAX GeneID HPRD
ERN1 Protein TNFRSF1A GeneID HPRD
ERN1 Protein HSP90AA1 GeneID HPRD
ERN1 Protein HSPA5 GeneID HPRD
ERN1 Protein PSEN1 GeneID HPRD
ERN1 BioGRID TAOK3 GeneID BioGRID Affinity Capture-Western
ERN1 BioGRID PSEN1 GeneID BioGRID Affinity Capture-Western
ERN1 BioGRID HSP90AA1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
StringDB
A B experiments database textmining combined score hadb nhadb
ERN1 RHOD 0 0 54 162 1 1
ERN1 ANKRD32 0 0 0 167 1 1
ERN1 S100A13 0 0 0 216 1 1
ERN1 ALG10 0 0 81 261 1 1
ERN1 SOCS3 0 0 181 233 1 1
ERN1 FASLG 0 0 194 194 1 1
ERN1 FAF1 0 0 0 155 1 1
ERN1 STAT5A 0 0 97 200 1 1
ERN1 AQP4 0 0 0 156 1 1
ERN1 MLST8 0 0 147 158 1 1
ERN1 KIAA1614 0 0 0 189 1 1
ERN1 UPF1 0 0 150 186 1 1
ERN1 DTX2 0 0 0 150 1 1
ERN1 RND2 0 0 0 150 1 1
ERN1 TSSK4 0 0 0 162 1 1
ERN1 KRAS 0 0 156 256 1 2
ERN1 FANCG 0 0 0 297 1 1
ERN1 PKN2 0 0 0 153 1 1
ERN1 ALG3 0 0 76 231 1 1
ERN1 FMO5 0 0 0 188 1 1
ERN1 ASH2L 103 0 0 166 1 1
ERN1 GYS1 0 0 0 157 1 1
ERN1 PSENEN 0 0 274 274 1 1
ERN1 PRKCSH 0 0 82 177 1 1
ERN1 FBXL19 0 0 0 175 1 1
ERN1 EEF1G 0 0 0 190 1 1
ERN1 MAPT 0 0 161 250 1 2
ERN1 BECN1 0 0 623 647 1 2
ERN1 ERLIN2 0 0 142 155 1 1
ERN1 TRMT10C 0 540 0 540 1 1
ERN1 PPM1A 0 0 0 198 1 1
ERN1 MPI 0 0 60 184 1 1
ERN1 CDKN2C 0 0 66 153 1 1
ERN1 ATXN3 0 0 136 171 1 2
ERN1 APH1A 0 0 261 261 1 1
ERN1 DNAJC10 0 0 392 487 1 1
ERN1 DUSP1 0 0 82 155 1 1
ERN1 MAPK11 0 0 48 180 1 1
ERN1 SAR1B 0 0 113 207 1 1
ERN1 SEC62 0 0 279 432 1 1
ERN1 ACADVL 0 0 329 329 1 1
ERN1 ENSG00000251246 0 0 0 168 1 1
ERN1 LPIN1 0 0 181 227 1 2
ERN1 SIGMAR1 0 0 796 796 1 1
ERN1 RHOBTB3 0 0 0 150 1 1
ERN1 REL 0 0 134 210 1 2
ERN1 ATG101 0 0 208 208 1 2
ERN1 NLRP3 0 0 455 463 1 2
ERN1 CEBPZ 0 0 322 321 1 1
ERN1 PTGS2 0 0 241 285 1 2
ERN1 PDIA6 0 0 514 537 1 1
ERN1 CASP3 0 0 682 689 1 2
ERN1 TMEM259 0 0 150 160 1 1
ERN1 COG7 0 0 0 212 1 1
ERN1 REN 0 0 125 202 1 1
ERN1 TNFRSF10B 0 0 526 547 1 2
ERN1 SRPK3 0 0 0 205 1 1
ERN1 PPM1B 0 0 0 198 1 1
ERN1 STX16 0 0 0 156 1 1
ERN1 MAPK15 0 0 0 154 1 1
ERN1 CYBB 0 0 324 373 1 2
ERN1 CDKN2A 0 0 127 208 1 2
ERN1 RPS27A 486 0 0 519 1 1
ERN1 UNC119 0 0 48 407 1 1
ERN1 PNPLA3 0 0 155 154 1 1
ERN1 NPLOC4 0 0 217 274 1 1
ERN1 ATG16L1 0 0 451 451 1 2
ERN1 CEBPB 0 0 364 375 1 2
ERN1 SMPD1 0 0 145 158 1 1
ERN1 NOD2 0 0 285 302 1 2
ERN1 PDIA4 0 0 520 676 1 1
ERN1 ACO1 0 0 51 326 1 1
ERN1 MORF4L1 0 0 0 328 1 1
ERN1 RIPK1 270 0 294 371 1 2
ERN1 ERO1LB 0 0 451 632 1 1
ERN1 CDR2 0 0 0 189 1 1
ERN1 SNAI1 0 0 142 155 1 1
ERN1 IL10 0 0 243 257 1 2
ERN1 GDF15 0 0 123 243 1 1
ERN1 DYRK1B 0 0 0 211 1 1
ERN1 DLG4 0 0 113 158 1 2
ERN1 NR1H4 0 0 155 186 1 1
ERN1 BCAP29 0 0 0 260 1 1
ERN1 TSEN34 0 360 56 370 1 1
ERN1 PDZK1IP1 0 0 0 187 1 1
ERN1 ATP7B 0 0 0 152 1 1
ERN1 CECR2 0 0 0 152 1 1
ERN1 BAG1 0 0 155 168 1 2
ERN1 TSSK6 0 0 0 157 1 1
ERN1 FKBP2 0 0 91 299 1 1
ERN1 KAT5 0 0 44 206 1 1
ERN1 MAN1A2 0 0 0 189 1 1
ERN1 NFE2L1 0 0 181 253 1 1
ERN1 CCNA1 0 0 161 215 1 1
ERN1 KIT 0 0 109 150 1 2
ERN1 RTCB 0 0 603 621 1 1
ERN1 AMBRA1 0 0 182 200 1 2
ERN1 CHD2 0 0 57 186 1 1
ERN1 SCARA3 0 0 238 237 1 1
ERN1 AGO1 0 720 0 737 1 1
ERN1 TELO2 0 0 0 199 1 1
ERN1 SIL1 0 0 261 386 1 1
ERN1 NME8 0 0 0 164 1 1
ERN1 SLC9C2 0 0 0 507 1 1
ERN1 STK40 0 0 0 162 1 1
ERN1 ACSL4 0 0 128 162 1 1
ERN1 SLC2A14 0 0 81 169 1 1
ERN1 IRF1 0 0 157 200 1 2
ERN1 MIB1 0 0 0 206 1 1
ERN1 PDIA5 0 0 325 370 1 1
ERN1 KDELR2 0 0 0 240 1 1
ERN1 UGGT2 0 0 66 326 1 1
ERN1 ILKAP 0 0 0 213 1 1
ERN1 ENSG00000279765 0 0 56 185 1 1
ERN1 CALCOCO2 0 0 205 205 1 2
ERN1 HSF4 0 0 0 214 1 1
ERN1 TXNDC5 0 0 216 252 1 1
ERN1 CHKB 0 0 0 176 1 1
ERN1 IFNB1 0 0 298 298 1 1
ERN1 ESR1 0 0 267 312 1 2
ERN1 PIM2 0 0 45 159 1 1
ERN1 UBQLN2 0 0 108 164 1 2
ERN1 OPTN 0 0 222 264 1 2
ERN1 PDK4 0 0 57 211 1 1
ERN1 PLIN2 0 0 260 260 1 2
ERN1 LMNB1 0 0 203 215 1 1
ERN1 FN1 0 0 212 212 1 2
ERN1 SURF4 0 0 137 289 1 1
ERN1 ULK1 0 0 369 234 1 2
ERN1 PKN3 0 0 0 153 1 1
ERN1 PKN1 0 0 0 153 1 1
ERN1 PRKCA 0 0 123 177 1 1
ERN1 INHBC 0 0 0 173 1 1
ERN1 EFNA2 0 0 0 168 1 1
ERN1 HMOX2 0 0 86 153 1 1
ERN1 SPHK1 0 0 304 314 1 2
ERN1 EIF2A 0 0 556 562 1 2
ERN1 PIGA 0 0 0 157 1 1
ERN1 HHAT 0 0 0 182 1 1
ERN1 MAP1LC3B 0 0 556 608 1 2
ERN1 CYB5D2 0 0 0 155 1 1
ERN1 UVRAG 0 0 194 213 1 2
ERN1 PARD6A 0 0 0 189 1 1
ERN1 ATF3 0 0 519 533 1 2
ERN1 G3BP1 0 0 122 154 1 1
ERN1 ZMPSTE24 0 0 48 171 1 1
ERN1 RAB7A 0 0 181 231 1 2
ERN1 BMF 0 0 137 199 1 1
ERN1 TXNIP 0 0 561 581 1 2
ERN1 RHOF 0 0 0 150 1 1
ERN1 TFRC 0 0 113 151 1 1
ERN1 GCG 0 0 297 297 1 1
ERN1 ATG4B 0 0 180 215 1 2
ERN1 RND3 0 0 0 150 1 1
ERN1 TCP1 0 0 70 166 1 1
ERN1 NFKB2 0 0 84 399 1 1
ERN1 UNC119B 0 0 0 199 1 1
ERN1 RBFOX3 0 0 160 212 1 1
ERN1 SLC7A11 0 0 164 203 1 2
ERN1 EEF2 0 0 171 199 1 2
ERN1 USP14 486 0 830 911 1 2
ERN1 STT3B 0 0 91 213 1 1
ERN1 PPP1R15A 0 0 754 780 1 2
ERN1 LAS1L 0 360 43 375 1 1
ERN1 ATP13A2 0 0 104 150 1 1
ERN1 FIS1 0 0 183 225 1 2
ERN1 FTHL17 0 0 0 264 1 1
ERN1 VAPB 0 0 211 243 1 1
ERN1 PIK3R2 0 0 310 358 1 1
ERN1 TRAP1 0 0 0 174 1 2
ERN1 DNAJC6 0 0 0 194 1 1
ERN1 NBR1 0 0 240 334 1 2
ERN1 TNF 0 0 954 957 1 2
ERN1 C22orf29 0 0 401 400 1 1
ERN1 SEL1L3 0 0 0 179 1 1
ERN1 CAT 0 0 403 430 1 2
ERN1 PDPK1 0 0 102 186 1 2
ERN1 HELZ2 0 0 0 150 1 1
ERN1 CCT6A 0 0 57 155 1 1
ERN1 CANX 0 0 681 755 1 2
ERN1 FAF2 0 0 291 375 1 1
ERN1 HRK 0 0 231 231 1 1
ERN1 NUMBL 0 0 0 159 1 1
ERN1 CDIPT 0 0 112 152 1 1
ERN1 LRP2BP 0 0 0 179 1 1
ERN1 HPRT1 0 0 167 171 1 1
ERN1 RNASEL 0 0 391 262 1 1
ERN1 DDIT4 0 0 244 260 1 2
ERN1 BAK1 213 0 307 453 1 2
ERN1 MAD2L2 0 0 0 301 1 1
ERN1 DNAJB2 0 0 47 155 1 1
ERN1 HSF2 0 0 0 238 1 1
ERN1 APEH 0 0 154 180 1 1
ERN1 SREBF2 0 0 369 390 1 1
ERN1 STAR 0 0 188 188 1 1
ERN1 ULK3 0 0 90 170 1 2
ERN1 CLIC3 0 0 0 150 1 1
ERN1 RBM24 0 0 0 204 1 1
ERN1 ALG12 0 0 114 359 1 1
ERN1 STIM1 0 0 181 181 1 2
ERN1 ATR 0 0 82 167 1 2
ERN1 BCL2L2 0 0 170 183 1 1
ERN1 LOX 0 0 150 164 1 2
ERN1 UBL4A 0 0 81 158 1 1
ERN1 CBL 0 0 54 161 1 1
ERN1 HSPA9 0 0 293 364 1 1
ERN1 IRS1 0 0 507 557 1 2
ERN1 REM1 0 0 0 161 1 1
ERN1 RPS6KB1 0 0 391 252 1 2
ERN1 TTBK1 0 0 0 169 1 1
ERN1 PGR 0 0 123 155 1 1
ERN1 YOD1 0 0 93 155 1 1
ERN1 EIF2AK3 0 0 874 452 1 2
ERN1 TUFT1 0 0 0 197 1 1
ERN1 ACLY 0 0 170 169 1 1
ERN1 STAT6 0 0 170 286 1 1
ERN1 FRMPD2 0 0 0 193 1 1
ERN1 ALAS2 0 0 0 227 1 1
ERN1 RPP40 0 720 0 720 1 1
ERN1 DNAJB11 0 0 466 508 1 1
ERN1 RABGEF1 0 0 0 171 1 1
ERN1 FLT1 0 0 85 162 1 1
ERN1 PSMB5 0 0 94 188 1 1
ERN1 SCD 0 0 365 393 1 1
ERN1 SRC 0 0 590 285 1 2
ERN1 GRAP 0 0 0 170 1 1
ERN1 FAM73A 0 0 70 311 1 1
ERN1 DGAT2 0 0 320 337 1 1
ERN1 MCU 0 0 213 213 1 2
ERN1 RPP25 0 720 0 720 1 1
ERN1 YWHAB 0 0 0 165 1 1
ERN1 ZFYVE1 0 0 137 218 1 2
ERN1 UPF3B 0 0 123 173 1 1
ERN1 BNIP3L 0 0 182 181 1 2
ERN1 TSC2 0 0 302 339 1 2
ERN1 PPM1D 0 0 0 213 1 1
ERN1 HACE1 0 0 0 170 1 1
ERN1 STX17 0 0 134 184 1 2
ERN1 TOMM20 0 0 150 170 1 2
ERN1 PTPRQ 0 0 0 181 1 1
ERN1 POP5 0 720 0 720 1 1
ERN1 EIF2S1 0 0 844 861 1 2
ERN1 HMOX1 0 0 420 429 1 2
ERN1 GLRX 0 0 150 192 1 1
ERN1 RHOH 0 0 0 150 1 1
ERN1 SEC13 0 0 151 322 1 1
ERN1 PPP2R4 0 0 256 292 1 1
ERN1 ASNS 0 0 294 310 1 1
ERN1 PDK3 0 0 48 203 1 1
ERN1 XIAP 0 0 318 371 1 2
ERN1 DIBD1 0 0 0 171 1 1
ERN1 DCTN5 0 0 0 400 1 1
ERN1 IKBKB 0 0 298 175 1 2
ERN1 ATF6 0 0 915 934 1 2
ERN1 CPE 0 0 143 155 1 1
ERN1 UBA5 0 0 145 161 1 1
ERN1 PRDM16 0 0 70 187 1 1
ERN1 UCKL1 0 0 0 195 1 1
ERN1 GNAL 0 0 0 158 1 1
ERN1 ATF4 0 0 805 813 1 2
ERN1 CD4 0 0 242 260 1 2
ERN1 PPARG 0 0 342 380 1 2
ERN1 MARCH6 0 0 208 295 1 1
ERN1 CAPN1 0 0 243 271 1 2
ERN1 TGFB2 0 0 60 166 1 1
ERN1 AKT1 0 0 562 293 1 2
ERN1 ERP29 0 0 290 364 1 1
ERN1 IRF3 0 0 232 244 1 2
ERN1 YIPF5 270 0 391 536 1 1
ERN1 TRIM2 0 0 0 153 1 1
ERN1 ERBB2 0 0 205 177 1 2
ERN1 GYS2 0 0 0 157 1 1
ERN1 ENSG00000274276 0 0 120 177 1 1
ERN1 FANCD2 0 0 0 206 1 1
ERN1 RPP30 0 720 0 726 1 1
ERN1 BBC3 0 0 325 325 1 2
ERN1 TAP1 0 0 137 173 1 1
ERN1 PYCARD 0 0 181 194 1 2
ERN1 TLR9 0 0 151 193 1 2
ERN1 ALAS1 0 0 0 227 1 1
ERN1 CXCL10 0 0 162 161 1 2
ERN1 USH2A 0 0 75 152 1 1
ERN1 RHOC 0 0 0 150 1 1
ERN1 EMD 0 0 141 200 1 1
ERN1 VCP 0 0 309 379 1 2
ERN1 CAPN2 0 0 173 186 1 2
ERN1 YWHAE 0 0 0 165 1 1
ERN1 LAMP2 0 0 228 256 1 2
ERN1 GOLGA2 0 0 150 171 1 1
ERN1 ERN2 0 540 828 566 1 1
ERN1 DNAJC3 0 0 681 710 1 1
ERN1 MIB2 0 0 0 206 1 1
ERN1 TTC3 0 0 45 192 1 1
ERN1 CD8A 0 0 267 278 1 1
ERN1 PEMT 0 0 73 295 1 1
ERN1 ERLEC1 0 0 293 434 1 1
ERN1 CALR 0 0 694 714 1 1
ERN1 BIK 0 0 324 338 1 2
ERN1 PSMB8 0 0 126 217 1 1
ERN1 FANCA 0 0 0 189 1 1
ERN1 XRN1 0 0 161 198 1 1
ERN1 SEL1L2 0 0 0 341 1 1
ERN1 CREB3 0 0 391 390 1 1
ERN1 RASD1 0 0 70 166 1 1
ERN1 TFAM 0 0 554 562 1 2
ERN1 TRIM3 0 0 665 671 1 1
ERN1 AKT1S1 0 0 164 177 1 1
ERN1 CASP1 0 0 406 419 1 2
ERN1 SLC35B4 0 0 0 258 1 1
ERN1 SNCA 0 0 367 376 1 2
ERN1 ULK2 0 0 179 153 1 2
ERN1 VRK2 0 0 0 169 1 1
ERN1 TNFSF10 0 0 217 217 1 2
ERN1 ORMDL3 0 0 282 376 1 2
ERN1 HSPA1A 270 0 832 886 1 1
ERN1 EARS2 0 0 0 391 1 1
ERN1 SERPINA1 0 0 244 262 1 2
ERN1 MAPK12 0 0 0 169 1 1
ERN1 BCL2L11 270 0 946 964 1 2
ERN1 KPNB1 0 0 122 195 1 1
ERN1 ITPR3 0 0 619 634 1 1
ERN1 RHOT1 0 0 95 188 1 1
ERN1 PLCG1 0 0 45 191 1 1
ERN1 PNPLA2 0 0 218 235 1 2
ERN1 PDIA2 0 0 232 456 1 1
ERN1 GGA2 0 0 0 202 1 1
ERN1 TFEB 0 0 209 232 1 2
ERN1 HPGDS 0 0 170 182 1 1
ERN1 ANKHD1-EIF4EBP3 0 0 0 158 1 1
ERN1 CEBPA 0 0 325 351 1 1
ERN1 HTRA2 0 0 160 197 1 1
ERN1 DYRK2 0 0 0 211 1 1
ERN1 COX4I1 0 0 211 223 1 1
ERN1 SGPL1 0 0 424 460 1 1
ERN1 ACTB 0 0 611 647 1 2
ERN1 INS 0 0 602 602 1 2
ERN1 GLP1R 0 0 154 167 1 1
ERN1 STUB1 270 0 209 472 1 2
ERN1 ALG5 0 0 66 275 1 1
ERN1 INHBE 0 0 0 173 1 1
ERN1 SIRT3 0 0 203 203 1 2
ERN1 CSNK1E 0 0 0 177 1 1
ERN1 B2M 0 0 155 154 1 1
ERN1 SCYL2 0 0 0 158 1 1
ERN1 KEAP1 0 0 342 342 1 2
ERN1 RNF5 0 0 202 202 1 1
ERN1 HSFX2 0 0 0 214 1 1
ERN1 ZBTB8OS 0 0 171 171 1 1
ERN1 NKRF 0 0 153 238 1 1
ERN1 LLGL2 0 0 0 167 1 1
ERN1 PARP1 0 0 310 367 1 2
ERN1 RHOA 0 0 123 223 1 2
ERN1 EIF4G1 0 0 140 170 1 2
ERN1 CRTC2 0 0 220 233 1 1
ERN1 HSPA8 0 0 310 379 1 2
ERN1 GSR 0 0 217 217 1 1
ERN1 TARDBP 0 0 181 224 1 2
ERN1 TLR5 0 0 112 156 1 1
ERN1 RHOQ 0 0 0 150 1 1
ERN1 MTTP 0 0 348 347 1 1
ERN1 MLKL 0 0 193 219 1 2
ERN1 NIM1K 0 0 0 162 1 1
ERN1 RHOG 0 0 42 151 1 1
ERN1 TRPT1 0 0 213 240 1 1
ERN1 ESR2 0 0 123 155 1 1
ERN1 SIRT7 0 0 181 181 1 2
ERN1 CCT4 0 0 0 262 1 1
ERN1 GABARAPL1 0 0 282 329 1 2
ERN1 PDK2 0 0 0 197 1 1
ERN1 LGALS4 0 0 399 399 1 1
ERN1 LLGL1 0 0 66 189 1 1
ERN1 DPP4 0 0 152 159 1 1
ERN1 VPS54 0 0 0 173 1 1
ERN1 CHMP3 0 0 47 152 1 1
ERN1 TSEN54 0 540 0 568 1 1
ERN1 IAPP 0 0 234 234 1 2
ERN1 ABCA1 0 0 148 182 1 2
ERN1 MAVS 0 0 224 252 1 2
ERN1 SPCS3 0 0 0 172 1 1
ERN1 RHOB 0 0 0 150 1 1
ERN1 DDX58 0 0 286 297 1 1
ERN1 SMG5 0 0 120 227 1 1
ERN1 SEC31B 0 0 86 223 1 1
ERN1 YWHAG 0 0 0 165 1 1
ERN1 HYOU1 0 0 504 691 1 1
ERN1 RAP2B 0 0 74 169 1 1
ERN1 SNX15 0 0 0 164 1 1
ERN1 MLXIPL 0 0 275 383 1 1
ERN1 SPPL2A 0 0 0 150 1 1
ERN1 AUP1 0 0 290 309 1 1
ERN1 TNFRSF10A 0 0 241 275 1 1
ERN1 RNF183 0 0 112 150 1 1
ERN1 SEC63 270 0 371 624 1 1
ERN1 ABCB6 0 0 0 164 1 1
ERN1 CASP8 0 0 518 542 1 2
ERN1 PPM1G 0 0 92 241 1 1
ERN1 EME2 0 540 0 540 1 1
ERN1 ALG1L2 0 0 0 157 1 1
ERN1 MAGT1 0 0 0 269 1 1
ERN1 LEPR 0 0 218 230 1 1
ERN1 HERPUD1 0 0 470 470 1 1
ERN1 KAT2A 0 0 149 275 1 1
ERN1 SEC23A 0 0 49 311 1 2
ERN1 GNAS 0 0 0 158 1 1
ERN1 TRIB1 0 0 0 162 1 1
ERN1 CEBPD 0 0 175 189 1 1
ERN1 NDUFAB1 0 0 60 338 1 1
ERN1 RPTOR 0 0 260 333 1 2
ERN1 DLG5 0 0 0 159 1 1
ERN1 BPTF 0 0 0 260 1 1
ERN1 MAPK9 0 0 390 270 1 2
ERN1 TLR7 0 0 161 202 1 2
ERN1 ITPR1 0 0 506 525 1 2
ERN1 CASP9 0 0 562 572 1 2
ERN1 FASN 0 0 254 269 1 2
ERN1 CD59 0 0 100 157 1 1
ERN1 ARG1 0 0 142 160 1 2
ERN1 GCLC 0 0 181 198 1 1
ERN1 PRKAB1 0 0 90 191 1 2
ERN1 SHANK2 0 0 0 174 1 1
ERN1 ADIPOQ 0 0 247 246 1 2
ERN1 GRAPL 0 0 0 170 1 1
ERN1 BCKDK 0 0 0 197 1 1
ERN1 IFIH1 0 0 160 173 1 1
ERN1 HSPA6 0 0 96 185 1 1
ERN1 HIST2H3PS2 0 0 160 181 1 1
ERN1 OTUB1 270 0 0 270 1 1
ERN1 TNS1 0 0 66 177 1 1
ERN1 CISH 0 0 75 152 1 1
ERN1 GRINA 0 0 113 167 1 1
ERN1 ENSG00000272772 0 0 0 199 1 1
ERN1 MAP2K5 0 0 0 185 1 1
ERN1 EIF2B5 0 0 113 150 1 1
ERN1 NFE2L2 0 0 456 490 1 2
ERN1 DNHD1 0 0 0 272 1 1
ERN1 PPIF 0 0 181 195 1 1
ERN1 DOLK 0 0 67 225 1 1
ERN1 MAP2K1 0 0 203 331 1 1
ERN1 FAM8A1 0 0 142 165 1 1
ERN1 FKBP7 0 0 123 200 1 1
ERN1 KDELR1 0 0 290 437 1 1
ERN1 SUCO 0 0 67 151 1 1
ERN1 SMAD4 0 0 102 163 1 2
ERN1 PPP3CC 0 0 0 151 1 1
ERN1 EFNA5 0 0 48 174 1 1
ERN1 PARK7 0 0 162 192 1 2
ERN1 STXBP6 0 0 0 167 1 1
ERN1 SHANK1 0 0 0 174 1 1
ERN1 AGO4 0 720 0 737 1 1
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ERN1 IL18 0 0 261 261 1 2
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ERN1 IRGM 0 0 249 248 1 2
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ERN1 HIPK1 0 0 0 193 1 1
ERN1 ATP1B1 0 0 328 328 1 1
ERN1 WFS1 0 0 410 418 1 1
ERN1 PPIG 0 0 134 151 1 1
ERN1 SNRPE 0 0 0 354 1 2
ERN1 SDHC 0 0 218 221 1 1
ERN1 IGF1R 0 0 162 161 1 2
ERN1 GATA3 0 0 62 175 1 1
ERN1 TRIM23 0 0 0 169 1 1
ERN1 SCNN1G 0 0 0 201 1 1
ERN1 VDAC2 0 0 413 432 1 1
ERN1 UBE2T 0 0 0 321 1 1
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ERN1 AGO2 0 720 88 750 1 2
ERN1 RBBP6 0 0 0 335 1 1
ERN1 MKKS 0 0 66 163 1 1
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ERN1 SKIV2L 0 0 195 204 1 1
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ERN1 SH3BP5 0 0 181 234 1 1
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ERN1 LMNA 0 0 172 184 1 2
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ERN1 SPECC1 0 0 99 156 1 1
ERN1 KLHDC2 0 0 0 180 1 1
ERN1 DDIT3 0 0 870 873 1 2
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ERN1 POLE 0 0 0 257 1 1
ERN1 SERP1 0 0 370 392 1 1
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ERN1 YWHAZ 0 0 49 171 1 1
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ERN1 RPP21 0 720 0 720 1 1
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ERN1 SEC11A 0 0 60 160 1 1
ERN1 RNF13 270 0 236 428 1 1
ERN1 HSPA5 835 800 989 999 1 2
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ERN1 TUSC3 0 0 45 272 1 1
ERN1 SOD2 0 0 245 290 1 2
ERN1 TPTE2 0 0 0 155 1 1
ERN1 FOXO1 0 0 370 420 1 2
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ERN1 POMT2 0 0 0 150 1 1
ERN1 PHB 0 0 134 196 1 1
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ERN1 LRRK2 0 0 241 233 1 2
ERN1 LYPD4 179 0 0 179 1 1
ERN1 TLR2 0 0 326 373 1 2
ERN1 CERS6 0 0 135 155 1 1
ERN1 PMAIP1 0 0 465 465 1 2
ERN1 PIM3 0 0 0 162 1 1
ERN1 PRKCH 0 0 0 153 1 1
ERN1 ANKRD45 0 0 0 507 1 1
ERN1 PEX3 0 0 96 273 1 2
ERN1 GALE 0 0 181 194 1 1
ERN1 FAM215A 0 0 181 181 1 1
ERN1 PDIA3 0 0 494 658 1 1
ERN1 CLIC1 0 0 0 150 1 1
ERN1 UGP2 0 0 0 180 1 1
ERN1 DNAJB9 0 0 735 764 1 2
ERN1 GNAI3 0 0 0 177 1 2
ERN1 NOD1 0 0 244 243 1 2
ERN1 ORMDL1 0 0 74 191 1 1
ERN1 LNX1 0 0 0 200 1 1
ERN1 RPS6KC1 0 0 0 164 1 1
ERN1 OS9 270 0 358 608 1 1
ERN1 HSPA1B 270 0 0 348 1 1
ERN1 GNA15 0 0 0 158 1 1
ERN1 UFL1 0 0 233 232 1 1
ERN1 GFPT1 0 0 134 184 1 1
ERN1 TRIB3 0 0 491 555 1 2
ERN1 GAPVD1 0 0 0 159 1 1
ERN1 NQO1 0 0 218 218 1 2
ERN1 ATG12 0 0 467 490 1 2
ERN1 KDELR3 0 0 0 184 1 1
ERN1 PRKCQ 0 0 60 160 1 2
ERN1 ANG 0 0 151 150 1 2
ERN1 HSPA4L 0 0 0 221 1 1
ERN1 PPIA 0 0 119 154 1 1
ERN1 ISYNA1 0 0 256 643 1 1
ERN1 GDF11 0 0 0 154 1 1
ERN1 BHLHA15 0 0 437 437 1 1
ERN1 SLC11A1 0 0 0 173 1 1
ERN1 ITGAX 0 0 156 185 1 1
ERN1 CASP4 0 0 601 621 1 2
ERN1 SFN 0 0 0 165 1 2
ERN1 CUL3 0 0 151 225 1 2
ERN1 PI4KA 0 0 95 178 1 1
ERN1 DNAJA2 0 0 0 206 1 1
ERN1 PRDM1 0 0 139 206 1 1
ERN1 EGFLAM 0 0 0 155 1 1
ERN1 YWHAH 0 0 73 192 1 1
ERN1 MON2 0 0 0 187 1 1
ERN1 DERL3 270 0 529 745 1 1
ERN1 GFAP 0 0 142 155 1 2
ERN1 NCK1 0 0 428 491 1 1
ERN1 FMN1 0 0 0 176 1 1
ERN1 EFNB2 0 0 0 168 1 1
ERN1 ACTG1 0 0 139 188 1 1
ERN1 ATG7 0 0 505 578 1 2
ERN1 PPP1R15B 0 0 324 353 1 1
ERN1 GNAI1 0 0 0 177 1 1
ERN1 ENSG00000267261 0 0 0 218 1 1
ERN1 ATM 0 0 194 232 1 2
ERN1 PLEKHG4B 0 0 0 165 1 1
ERN1 PREB 0 0 70 235 1 1
ERN1 CTSD 0 0 212 281 1 2
ERN1 MAPK10 0 0 206 210 1 2
ERN1 NPY1R 0 0 0 162 1 1
ERN1 UCP1 0 0 232 231 1 2
ERN1 FAM134B 0 0 267 267 1 1
ERN1 UIMC1 0 0 0 212 1 1
ERN1 SREBF1 0 0 469 498 1 1
ERN1 DNAJC1 0 0 144 218 1 1
ERN1 MAPK14 0 0 213 272 1 2
ERN1 PARP16 0 0 394 407 1 1
ERN1 NFKBIA 0 0 325 388 1 2
ERN1 RHOT2 0 0 60 157 1 1
ERN1 LEP 0 0 341 341 1 1
ERN1 ATAD2B 0 0 0 160 1 1
ERN1 ZC3H12A 0 0 250 303 1 1
ERN1 TCF4 0 0 263 263 1 1
ERN1 ORMDL2 0 0 95 213 1 1
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ERN1 SEC24A 270 0 97 357 1 1
ERN1 PRKAA2 0 0 70 171 1 2
ERN1 WIPI1 0 0 187 214 1 2
ERN1 TRAF7 0 0 50 181 1 1
ERN1 DNM1L 0 0 264 293 1 2
ERN1 DYRK4 0 0 0 211 1 1
ERN1 PTEN 0 0 268 355 1 2
ERN1 VEGFA 0 0 387 386 1 2
ERN1 IRF4 0 0 140 171 1 1
ERN1 FSD1L 0 0 234 248 1 1
ERN1 MAPK7 0 0 90 190 1 1
ERN1 STXBP5L 0 0 0 167 1 1
ERN1 GABARAP 0 0 168 223 1 2
ERN1 PTPN1 0 0 534 562 1 1
ERN1 UFM1 0 0 202 216 1 1
ERN1 MANF 0 0 426 430 1 1
ERN1 GATA6 0 0 0 156 1 1
ERN1 HIPK2 0 0 102 216 1 2
ERN1 STAT2 0 0 95 194 1 1
ERN1 IGSF9 0 0 0 243 1 1
ERN1 RPP38 0 720 0 725 1 1
ERN1 XBP1 0 800 986 997 1 2
ERN1 ATG5 0 0 561 576 1 2
ERN1 UGGT1 0 0 263 468 1 1
ERN1 COPS5 486 0 794 891 1 1
ERN1 DUOX2 0 0 123 201 1 1
ERN1 HMGB1 0 0 210 224 1 2
ERN1 RAC1 0 0 66 202 1 2
ERN1 PPP1CA 0 0 95 178 1 1
ERN1 MAPK6 0 0 0 154 1 1
ERN1 MAP3K5 728 800 989 973 1 1
ERN1 ITGAM 0 0 187 215 1 1
ERN1 GATA2 0 0 45 160 1 1
ERN1 RGS1 0 0 90 157 1 1
ERN1 BACE1 0 0 181 253 1 2
ERN1 GNA11 0 0 0 158 1 1
ERN1 SIRT1 0 0 386 386 1 2
ERN1 MCL1 0 0 464 472 1 2
ERN1 ACOX1 0 0 151 151 1 1
ERN1 CTSB 0 0 233 259 1 2
ERN1 NOX1 0 0 187 245 1 1
ERN1 DPM1 0 0 63 290 1 1
ERN1 SEC22B 0 0 123 263 1 1
ERN1 SEC61B 270 0 329 559 1 1
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ERN1 GPX1 0 0 183 183 1 1
ERN1 IKBKG 0 0 171 186 1 1
ERN1 ATP8A1 0 0 0 168 1 1
ERN1 DNAJB8 0 0 48 154 1 1
ERN1 SEL1L 486 0 551 835 1 1
ERN1 NEK2 0 0 0 150 1 1
ERN1 NFKBIB 0 0 53 165 1 1
ERN1 SMG6 0 0 164 266 1 1
ERN1 FAM175A 0 0 0 256 1 1
ERN1 KPTN 0 0 0 208 1 1
ERN1 HSPB1 0 0 252 272 1 2
ERN1 DYRK1A 0 0 66 232 1 1
ERN1 HSPB2 0 0 243 263 1 1
ERN1 HERPUD2 0 0 151 152 1 1
ERN1 ATG10 0 0 234 234 1 2
ERN1 UBE2J2 0 0 50 156 1 1
ERN1 RT14 0 0 421 420 1 1
ERN1 APOB 0 0 294 309 1 2
ERN1 IGF1 0 0 249 248 1 2
ERN1 MAPK1 0 0 97 205 1 2
ERN1 SOCS1 0 0 94 152 1 1
ERN1 RAB39A 0 0 0 159 1 1
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ERN1 GADD45A 0 0 170 169 1 1
ERN1 PKM 0 0 96 162 1 1
ERN1 SEC61A2 0 0 63 269 1 1
ERN1 MUS81 0 540 0 546 1 1
ERN1 UBE2J1 0 0 218 273 1 1
ERN1 SDF2L1 0 0 213 248 1 1
ERN1 BCAP31 0 0 358 402 1 1
ERN1 FGF2 0 0 180 179 1 2
ERN1 PRDX4 0 0 213 230 1 1
ERN1 IFNAR1 0 0 170 182 1 1
ERN1 ASB11 0 0 74 160 1 1
ERN1 IREB2 0 0 0 318 1 1
ERN1 PGAP1 0 0 87 210 1 1
ERN1 PIGG 0 0 0 170 1 1
ERN1 SOS1 0 0 66 170 1 1
ERN1 PPTC7 0 0 0 198 1 1
ERN1 EDEM1 0 0 760 800 1 2
ERN1 TSSK1B 0 0 0 162 1 1
ERN1 CBSL 0 0 120 177 1 1
ERN1 ABI2 0 0 0 165 1 1
ERN1 APH1B 0 0 325 325 1 1
ERN1 BDNF 0 0 216 228 1 2
ERN1 KIAA0141 0 0 0 179 1 1
ERN1 LMCD1 0 0 0 160 1 1
ERN1 GNAI2 0 0 0 177 1 1
ERN1 CASP2 0 0 519 544 1 1
ERN1 ABHD5 0 0 161 174 1 1
ERN1 HIPK3 0 0 57 199 1 1
ERN1 RPP14 0 720 0 720 1 1
ERN1 TANK 0 0 329 340 1 2
ERN1 SDK2 0 0 0 171 1 1
ERN1 CDC42BPB 0 0 0 210 1 1
ERN1 PECAM1 0 0 142 155 1 1
ERN1 FANCI 0 0 0 275 1 1
ERN1 TSSK2 0 0 0 158 1 1
ERN1 LCP1 0 0 0 150 1 1
ERN1 TXN 0 0 412 439 1 1
ERN1 SMG7 0 0 68 182 1 1
ERN1 NUBP2 0 0 136 164 1 1
ERN1 INADL 0 0 0 159 1 1
ERN1 RHEB 0 0 257 333 1 2
ERN1 UBFD1 0 0 0 435 1 1
ERN1 MAP2K2 0 0 0 195 1 1
ERN1 PHLPP2 0 0 0 162 1 1
ERN1 GNB2L1 0 720 837 953 1 1
ERN1 LPCAT3 0 0 136 159 1 1
ERN1 TRPS1 0 0 0 156 1 1
ERN1 EFNA1 0 0 0 168 1 1
ERN1 ATP2A2 0 0 144 257 1 1
ERN1 UAP1 0 0 61 179 1 1
ERN1 DNAJB12 0 0 0 156 1 1
ERN1 CCND1 0 0 325 325 1 2
ERN1 SRPR 0 0 113 150 1 1
ERN1 LRGUK 0 0 0 161 1 1
ERN1 PRKAA1 0 0 90 179 1 2
ERN1 PPM1K 0 0 0 213 1 1
ERN1 NOS3 0 0 289 320 1 2
ERN1 NCF1 0 0 166 165 1 1
ERN1 LHFPL1 0 0 0 296 1 1
ERN1 FAU 0 0 0 162 1 2
ERN1 STX2 0 0 113 162 1 1
ERN1 TXNDC11 0 0 0 228 1 1
ERN1 HMGCR 0 0 240 288 1 1
ERN1 KAT2B 0 0 74 211 1 1
ERN1 YWHAQ 0 0 74 193 1 1
ERN1 BAD 0 0 155 181 1 2
ERN1 PRKDC 0 0 60 156 1 2
ERN1 PPP2CA 0 0 0 157 1 1
ERN1 EIF4E 0 0 254 324 1 2
ERN1 RNF139 0 0 150 276 1 1
ERN1 RTN3 0 0 174 187 1 1
ERN1 FMO2 0 0 56 200 1 1
ERN1 ATG3 0 0 322 358 1 2
ERN1 DNAJB1 0 0 403 470 1 2
ERN1 ANKRD17 0 0 0 158 1 1
ERN1 BIRC6 0 0 55 168 1 1
ERN1 TLR3 0 0 210 265 1 2
ERN1 CDKN3 0 0 95 167 1 1
ERN1 UAP1L1 0 0 0 162 1 1
ERN1 VIMP 0 0 244 243 1 1
ERN1 DKC1 0 0 47 194 1 1
ERN1 RAG1 0 540 73 555 1 1
ERN1 CDC42 0 0 150 274 1 2
ERN1 GATA5 0 0 0 156 1 1
ERN1 FOXO3 0 0 233 335 1 2
ERN1 VDAC3 0 0 142 170 1 1
ERN1 SLC2A4 0 0 209 285 1 1
ERN1 FMNL1 0 0 0 158 1 1
ERN1 APOE 0 0 262 262 1 2
ERN1 CLP1 0 720 0 720 1 1
ERN1 MAP3K6 0 0 0 151 1 1
ERN1 PRKCD 0 0 218 221 1 2
ERN1 UBR1 0 0 62 173 1 1
ERN1 ALG2 0 0 0 179 1 1
ERN1 TGFB1 0 0 58 187 1 2
ERN1 VDAC1 0 0 414 425 1 2
ERN1 RAB7B 0 0 181 231 1 1
ERN1 STAT5B 0 0 101 212 1 1
ERN1 LRIT3 0 0 0 198 1 1
ERN1 POP7 0 720 0 724 1 1
ERN1 RAC2 0 0 70 206 1 1
ERN1 RAB11A 0 0 73 168 1 2
ERN1 YY1 0 0 96 153 1 1
ERN1 ATF6B 0 0 398 497 1 1
ERN1 MARCH5 270 0 122 331 1 1
ERN1 PARD6G 0 0 0 189 1 1
ERN1 KDR 0 0 300 359 1 2
ERN1 SKP1 0 0 96 167 1 2
ERN1 FOXP3 0 0 96 183 1 2
ERN1 POP4 0 720 0 724 1 1
ERN1 RNF216 0 0 0 174 1 1
ERN1 DROSHA 0 720 71 734 1 1
ERN1 NOX4 0 0 340 384 1 2
ERN1 ARF4 0 0 108 200 1 1
ERN1 TMED10 0 0 55 256 1 1
ERN1 ATP7A 0 0 59 168 1 1
ERN1 SDF2 0 0 150 188 1 1
ERN1 ACACB 0 0 128 179 1 1
ERN1 CREB3L4 0 0 390 390 1 1
ERN1 DUOX1 0 0 139 215 1 1
ERN1 DNAJB14 0 0 0 156 1 1
ERN1 TPT1 0 0 171 183 1 1
ERN1 XRRA1 0 0 0 400 1 1
ERN1 FAS 0 0 150 434 1 2
ERN1 MAP3K15 0 0 0 179 1 1
ERN1 SPPL2B 0 0 0 150 1 1
ERN1 RAE1 0 0 0 165 1 1
ERN1 VCAM1 0 0 180 179 1 1
ERN1 DERL2 0 0 310 510 1 1
ERN1 HSPH1 0 0 70 167 1 1
ERN1 ATP2A3 0 0 150 197 1 1
ERN1 MBTPS1 0 0 602 675 1 1
ERN1 CPT1A 0 0 155 173 1 1
ERN1 PRDM4 0 0 0 349 1 1
ERN1 ST8SIA4 0 0 241 240 1 1
ERN1 KLHDC9 0 0 0 180 1 1
ERN1 EFNB3 0 0 0 168 1 1
ERN1 CSF2 0 0 154 153 1 1
ERN1 PPM1E 0 0 0 213 1 1
ERN1 NGF 0 0 150 163 1 2
ERN1 AGO3 0 720 0 737 1 1
ERN1 TH 0 0 163 163 1 2
ERN1 PRKRA 0 720 0 738 1 1
ERN1 HSP90AB1 0 0 0 444 1 2
ERN1 RTN4 0 0 159 173 1 1
ERN1 EIF4EBP1 0 0 340 390 1 2
ERN1 SSR2 0 0 90 180 1 1
ERN1 PHGDH 0 0 108 156 1 1
ERN1 GPT 0 0 294 320 1 1
ERN1 CLGN 0 0 0 264 1 1
ERN1 PPP3CA 0 0 0 151 1 1
ERN1 PINK1 0 0 282 305 1 2
ERN1 PP2D1 0 0 0 213 1 1
ERN1 CREB3L2 0 0 390 390 1 1
ERN1 EYS 0 0 0 181 1 1
ERN1 UBXN8 0 0 90 198 1 1
ERN1 GRB2 0 0 75 200 1 1
ERN1 LRIT1 0 0 0 198 1 1
ERN1 ABI1 0 0 0 165 1 1
ERN1 ANKHD1 0 0 0 158 1 1
ERN1 SOD1 0 0 355 399 1 2
ERN1 IRS2 0 0 268 342 1 1
ERN1 CLIP4 0 0 0 163 1 1
ERN1 UCHL1 270 0 82 313 1 2
ERN1 MFN1 0 0 218 232 1 2
ERN1 EIF2AK2 0 0 517 336 1 2
ERN1 AWAT1 0 0 160 179 1 1
ERN1 ALG6 0 0 45 209 1 1
ERN1 PPM1F 0 0 0 213 1 1
ERN1 CCNA2 0 0 149 204 1 1
ERN1 UBXN4 0 0 96 192 1 1
ERN1 GORASP2 0 0 171 171 1 1
ERN1 EIF2AK1 0 0 455 271 1 1
ERN1 INA 0 0 150 163 1 1
ERN1 DNTT 0 0 392 392 1 1
ERN1 BOK 0 0 151 165 1 1
ERN1 SH2D3C 0 0 180 197 1 1
ERN1 PIK3CG 0 0 61 172 1 1
ERN1 STXBP5 0 0 0 167 1 1
ERN1 ALG8 0 0 0 245 1 1
ERN1 AIF1 0 0 156 208 1 2
ERN1 ALG10B 0 0 64 247 1 1
ERN1 AMFR 0 0 284 390 1 1
ERN1 ENSG00000173366 0 0 151 205 1 1
ERN1 TRIO 0 0 0 169 1 1
ERN1 ERGIC3 0 0 143 171 1 1
ERN1 TSEN2 0 540 0 540 1 1
ERN1 RABEPK 0 0 0 180 1 1
ERN1 CLIC5 0 0 0 156 1 1
ERN1 DAPK1 0 0 161 185 1 2
ERN1 JUN 0 0 789 794 1 2
ERN1 POP1 0 720 0 720 1 1
ERN1 ETNK2 0 0 0 170 1 1
ERN1 UFD1L 0 0 251 260 1 1
ERN1 HSP90AA1 270 0 807 873 1 2
ERN1 CREB3L1 0 0 372 372 1 1
ERN1 KLHDC1 0 0 0 181 1 1
ERN1 RHOV 0 0 0 150 1 1
ERN1 ELF2 0 0 172 226 1 1
ERN1 ATF2 0 0 150 187 1 1
ERN1 PSEN1 270 800 270 887 1 2
ERN1 DNAJA4 0 0 60 221 1 1
ERN1 GNA14 0 0 0 158 1 1
ERN1 ATG13 0 0 310 309 1 2
ERN1 EDEM2 0 0 377 468 1 1
ERN1 GRAP2 0 0 0 186 1 1
ERN1 ABCG1 0 0 90 152 1 2
ERN1 MAPK3 0 0 335 285 1 2
ERN1 RND1 0 0 0 150 1 1
ERN1 MMP9 0 0 181 181 1 2
ERN1 SQSTM1 0 0 580 612 1 2
ERN1 BNIP3 0 0 233 232 1 2
ERN1 SLC11A2 0 0 0 173 1 1
ERN1 NIPBL 0 0 0 155 1 1
ERN1 PCK2 0 0 143 150 1 1
ERN1 ENSG00000249884 0 0 47 152 1 1
ERN1 ATG9A 0 0 134 231 1 2
ERN1 ERP44 0 0 359 388 1 1
ERN1 CDKN1A 63 0 157 191 1 2
ERN1 AR 0 0 150 181 1 2
ERN1 GANC 0 0 0 314 1 1
ERN1 BID 0 0 207 207 1 2
ERN1 GNA12 0 0 0 177 1 1
ERN1 TIMP1 0 0 118 153 1 1
ERN1 KLHDC10 0 0 0 180 1 1
ERN1 BAX 270 0 501 627 1 2
ERN1 ENSG00000271810 0 0 0 150 1 1
ERN1 HUNK 0 0 0 158 1 1
ERN1 UBE2G2 0 0 102 458 1 1
ERN1 PTPRC 0 0 162 236 1 1
ERN1 SAR1A 0 0 182 269 1 1
ERN1 RNF8 0 0 0 363 1 1
ERN1 HBS1L 0 0 69 164 1 1
ERN1 ICAM1 0 0 181 204 1 2
ERN1 SEC31A 0 0 150 277 1 1
ERN1 IGDCC3 0 0 0 184 1 1
ERN1 GATA1 0 0 45 160 1 1
ERN1 SPPL2C 0 0 0 150 1 1
ERN1 TRADD 0 0 188 200 1 1
ERN1 ATP2A1 0 0 217 260 1 1
ERN1 MAGI3 0 0 0 160 1 1
ERN1 SGK494 0 0 0 237 1 1
ERN1 CDH1 0 0 182 195 1 2
ERN1 SUPT20H 0 0 0 342 1 1
ERN1 VPS35 0 0 0 241 1 2
ERN1 TPTE 0 0 0 155 1 1
ERN1 IL4 0 0 182 181 1 1
ERN1 EP300 0 0 142 218 1 2
ERN1 PDGFRB 0 0 112 187 1 2
ERN1 NUMB 0 0 0 159 1 1
ERN1 TARBP2 0 720 0 738 1 1
ERN1 SNCAIP 0 0 84 169 1 2
ERN1 ROCK1 0 0 95 162 1 2
ERN1 ERO1L 0 0 685 789 1 1
ERN1 BIRC3 0 0 112 206 1 1
ERN1 ANXA8 0 0 224 224 1 1
ERN1 SMAD3 0 0 95 157 1 2
ERN1 SEC23B 0 0 108 353 1 2
ERN1 CD68 0 0 167 219 1 2
ERN1 ALB 0 0 459 470 1 2
ERN1 CCL2 0 0 329 329 1 2
ERN1 CDC37 0 0 704 712 1 1
ERN1 CREB3L3 0 0 557 566 1 1
ERN1 EIF4A1 0 0 126 161 1 1
ERN1 CSNK1D 0 0 0 177 1 1
ERN1 ELAVL1 0 0 113 162 1 2
ERN1 CUL1 0 0 92 172 1 1
ERN1 CASP7 0 0 455 479 1 1
ERN1 SORBS3 0 0 0 200 1 1
ERN1 DICER1 0 720 170 775 1 1
ERN1 PIK3R1 0 0 203 259 1 1
ERN1 DYRK3 0 0 0 211 1 1
ERN1 GPHN 0 0 0 152 1 1
ERN1 ALPK1 0 0 54 419 1 1
ERN1 HSPA4 0 0 505 556 1 1
ERN1 PDZD2 0 0 0 159 1 1
ERN1 GATA4 0 0 67 226 1 2
ERN1 PPARA 0 0 375 411 1 2
ERN1 NFYA 0 0 45 207 1 1
ERN1 LPL 0 0 168 167 1 1
ERN1 TEK 0 0 72 150 1 1
ERN1 HSP90B1 0 0 777 813 1 1
ERN1 CYP2E1 0 0 283 294 1 2
ERN1 HSPB3 0 0 254 274 1 1
ERN1 GGA1 0 0 0 152 1 1
ERN1 GADD45B 0 0 384 384 1 1
ERN1 CYCS 0 0 566 569 1 2
ERN1 PPM1L 0 0 113 272 1 1
ERN1 RAC3 0 0 0 181 1 2
ERN1 PDP1 0 0 0 198 1 1
ERN1 TRAF6 270 0 427 624 1 2
ERN1 KIAA0391 0 720 0 720 1 1
ERN1 GAK 0 0 0 245 1 1
ERN1 BFAR 0 0 232 277 1 1
ERN1 MLXIP 0 0 54 241 1 1
ERN1 GNAZ 0 0 0 177 1 1
ERN1 HNF1A 0 0 182 199 1 1
ERN1 EGF 0 0 235 246 1 2
ERN1 HGSNAT 0 0 233 232 1 1
ERN1 BMP2 0 0 136 234 1 1
ERN1 MAPK8 0 0 594 351 1 2
ERN1 EIF2S2 0 0 184 183 1 1
ERN1 CLIC2 0 0 0 150 1 1
ERN1 PLD1 0 0 306 321 1 2
ERN1 MAP2K4 0 0 236 157 1 1
ERN1 SESN2 0 0 195 209 1 2
ERN1 DDRGK1 0 0 296 296 1 1
ERN1 CDK5RAP3 0 0 155 154 1 1
ERN1 DIABLO 0 0 232 245 1 2
ERN1 CHKA 0 0 104 231 1 1
ERN1 MBTPS2 0 0 605 667 1 1
ERN1 PPP2CB 0 0 0 157 1 1
ERN1 SRPK1 0 0 0 205 1 1
ERN1 PRNP 0 0 155 154 1 2
ERN1 FBXO11 270 0 0 298 1 1
ERN1 FKBP11 0 0 195 266 1 1
ERN1 DAB2IP 0 360 250 581 1 2
ERN1 NAP1L2 0 0 54 155 1 1
ERN1 RB1CC1 0 0 466 466 1 2
ERN1 ALG11 0 0 0 157 1 1
ERN1 YRDC 0 0 0 240 1 1
ERN1 SSR1 0 0 134 229 1 1
ERN1 CHAC1 0 0 244 246 1 1
ERN1 SEC24C 270 0 127 346 1 1
ERN1 STK11 0 0 194 213 1 2
ERN1 LEMD3 0 0 0 230 1 1
ERN1 GPR78 0 0 504 512 1 1
ERN1 MDC1 0 0 0 256 1 1
ERN1 SLC2A3 0 0 74 163 1 1
ERN1 FLNA 0 0 689 708 1 1
ERN1 XRCC3 0 0 0 243 1 1
ERN1 GOLPH3 0 0 323 335 1 1
ERN1 CASP10 0 0 145 183 1 1
ERN1 WDR64 0 0 0 158 1 1
ERN1 GNAQ 0 0 0 158 1 1
ERN1 TMBIM6 0 0 982 982 1 1
ERN1 P4HB 0 0 681 784 1 2
ERN1 RICTOR 0 0 181 257 1 2
ERN1 PIM1 0 0 0 162 1 1
ERN1 G6PC 0 0 258 278 1 1
ERN1 IGFBPL1 0 0 0 158 1 1
ERN1 IFNA1 0 0 170 169 1 1
ERN1 NR0B2 0 0 151 200 1 1
ERN1 PARK2 0 0 235 262 1 1
ERN1 ASNA1 0 0 100 164 1 1
ERN1 LGMN 0 0 43 164 1 1
ERN1 DGAT1 0 0 201 220 1 2
ERN1 BLOC1S1 0 0 407 407 1 1
ERN1 PCK1 0 0 140 175 1 1
ERN1 PPARGC1A 0 0 369 384 1 2
ERN1 ABI3 0 0 0 165 1 1
ERN1 RAB8A 0 0 81 150 1 2
ERN1 GCLM 0 0 178 177 1 1
ERN1 SERPINH1 0 0 346 346 1 1
ERN1 AATF 0 0 139 158 1 1
ERN1 RPN1 0 0 143 340 1 1
ERN1 FANCC 0 0 0 221 1 1
ERN1 CD300C 0 0 195 195 1 1
ERN1 RHBDL3 0 0 0 153 1 1
ERN1 CPVL 0 0 0 171 1 1
ERN1 ETNK1 0 0 0 179 1 1
ERN1 EIF2AK4 0 0 523 340 1 2
ERN1 GNAT1 0 0 0 177 1 1
ERN1 APAF1 0 0 324 377 1 2
ERN1 HDAC6 0 0 218 264 1 2
ERN1 C19orf24 0 0 0 168 1 1
ERN1 TP53RK 0 0 75 224 1 1
ERN1 SFTPC 0 0 180 179 1 1
ERN1 PSMD10 0 0 54 155 1 1
ERN1 MIA3 0 0 167 185 1 1
ERN1 MELK 0 0 0 158 1 1
ERN1 CLU 0 0 261 261 1 2
ERN1 VRK3 0 0 0 169 1 1
ERN1 B3GNTL1 0 0 0 222 1 1
ERN1 MED8 0 0 0 193 1 1
ERN1 NFKBIZ 0 0 0 156 1 1
ERN1 DNAJA1 0 0 64 225 1 1
ERN1 MAP1A 0 0 323 366 1 2
ERN1 CTSA 0 0 0 171 1 1
ERN1 NPY4R 0 0 0 162 1 1
ERN1 TNS3 0 0 0 155 1 1
ERN1 INSIG1 0 0 281 298 1 1
ERN1 RAB2A 0 0 155 242 1 1
ERN1 TP53 270 0 459 594 1 2
ERN1 MDM2 0 0 166 179 1 2
ERN1 PPP1CC 0 0 218 290 1 1
ERN1 HTT 0 0 293 313 1 2
ERN1 HS3ST2 0 0 0 272 1 1
ERN1 EGFR 0 0 261 201 1 2
ERN1 CFLAR 0 0 251 290 1 2
ERN1 ANKFY1 0 0 0 159 1 1
ERN1 SLC2A1 0 0 160 241 1 2
ERN1 ASB7 0 0 83 158 1 1
ERN1 LAMP1 0 0 200 242 1 2
ERN1 GNA13 0 0 0 177 1 1
ERN1 IGFBP7 0 0 56 150 1 1
ERN1 CTRL 0 0 287 298 1 2
ERN1 PLIN1 0 0 181 181 1 1
ERN1 PIK3C3 0 0 284 393 1 2
ERN1 CLK3 0 0 0 174 1 1
ERN1 HSFX1 0 0 0 214 1 1
ERN1 SYVN1 835 0 735 976 1 1
ERN1 PADI1 0 0 296 296 1 1
ERN1 RAD51C 0 0 0 284 1 1
ERN1 BCL2L2-PABPN1 0 0 149 170 1 1
ERN1 STAT1 0 0 212 298 1 2
ERN1 ENDOG 0 0 294 315 1 1
ERN1 HHATL 0 0 0 169 1 1
ERN1 CRELD2 0 0 310 309 1 1
ERN1 TRIB2 0 0 0 162 1 1
ERN1 RAD51 0 0 46 229 1 2
ERN1 MAN1B1 0 0 181 198 1 1
ERN1 TAOK3 270 0 465 430 1 1
ERN1 MTOR 0 0 503 555 1 2
ERN1 MFN2 0 0 436 446 1 2
ERN1 APP 0 0 254 296 1 2
ERN1 ENSG00000258989 0 0 0 172 1 1
ERN1 HRAS 0 0 212 293 1 2
ERN1 CTNNB1 0 0 244 328 1 2
ERN1 IGSF9B 0 0 0 237 1 1
ERN1 ALG1 0 0 0 157 1 1
ERN1 PASK 0 0 0 162 1 1
ERN1 RHOBTB1 0 0 0 150 1 1
ERN1 TGFBRAP1 0 0 0 152 1 1
ERN1 VRK1 0 0 0 169 1 1
ERN1 ALG9 0 0 0 171 1 1
ERN1 RAB5A 0 0 136 185 1 2
ERN1 SEC11C 0 0 69 193 1 1
ERN1 EDEM3 0 0 261 297 1 1
ERN1 POMT1 0 0 0 150 1 1
ERN1 BAG3 0 0 152 203 1 2
ERN1 RPL30 0 0 0 208 1 1
ERN1 ARF3 0 0 66 162 1 1
ERN1 SEC24B 270 0 166 406 1 1
ERN1 CXCL8 0 0 324 340 1 2
ERN1 ALG1L 0 0 0 157 1 1
ERN1 GAPDH 0 0 566 582 1 2
ERN1 TMBIM4 0 0 453 508 1 1
ERN1 TM7SF2 0 0 82 232 1 1
ERN1 MAP2K7 0 0 260 313 1 1
ERN1 TSSK3 0 0 0 158 1 1
ERN1 ABL1 0 0 122 166 1 1
ERN1 RD3 0 0 180 179 1 1
ERN1 ARL5B 0 0 73 168 1 1
ERN1 MOGS 0 0 123 293 1 1
ERN1 SMG1 0 0 90 183 1 1
ERN1 FANCB 0 0 0 303 1 1
ERN1 ZGLP1 0 0 0 156 1 1
ERN1 RELA 0 0 194 222 1 2
ERN1 NFKB1 0 0 95 305 1 2
ERN1 RHOJ 0 0 0 150 1 1
ERN1 ATP13A1 0 0 66 161 1 1
ERN1 MAP1LC3B2 0 0 0 155 1 1
ERN1 DPAGT1 0 0 184 314 1 1
ERN1 HSF1 0 0 235 392 1 2
ERN1 GRID2IP 0 0 0 261 1 1
ERN1 SIRT2 0 0 194 194 1 2
ERN1 DGCR8 0 720 49 727 1 1
ERN1 CREBBP 0 0 84 165 1 1
ERN1 RHOBTB2 0 0 0 150 1 1
ERN1 ACO2 0 0 52 234 1 1
ERN1 SDHB 0 0 123 259 1 1
ERN1 ESRRA 0 0 67 196 1 1
ERN1 CDNF 0 0 166 165 1 1
ERN1 CREB1 0 0 393 392 1 2
ERN1 EFNB1 0 0 0 168 1 1
ERN1 DHX9 0 720 0 731 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0043531 Molecular Function ADP binding enables IDA
GO:0005524 Molecular Function ATP binding enables IDA
GO:0030544 Molecular Function Hsp70 protein binding enables IPI
GO:0051879 Molecular Function Hsp90 protein binding enables IDA
GO:0004521 Molecular Function RNA endonuclease activity enables IBA
GO:0004521 Molecular Function RNA endonuclease activity enables IDA
GO:0019899 Molecular Function enzyme binding enables IPI
GO:0042802 Molecular Function identical protein binding enables IPI
GO:0000287 Molecular Function magnesium ion binding enables IDA
GO:0005161 Molecular Function platelet-derived growth factor receptor binding enables IPI
GO:0005515 Molecular Function protein binding enables IPI
GO:0042803 Molecular Function protein homodimerization activity enables IDA
GO:0042803 Molecular Function protein homodimerization activity enables IPI
GO:0042803 Molecular Function protein homodimerization activity enables ISS
GO:0106310 Molecular Function protein serine kinase activity enables IEA
GO:0004674 Molecular Function protein serine/threonine kinase activity enables IBA
GO:0004674 Molecular Function protein serine/threonine kinase activity enables IDA
GO:0051082 Molecular Function unfolded protein binding enables IBA
GO:0036498 Biological Process IRE1-mediated unfolded protein response involved_in IBA
GO:0036498 Biological Process IRE1-mediated unfolded protein response involved_in IDA
GO:0036498 Biological Process IRE1-mediated unfolded protein response involved_in IMP
GO:0071333 Biological Process cellular response to glucose stimulus involved_in IDA
GO:0070301 Biological Process cellular response to hydrogen peroxide involved_in IEA
GO:0034620 Biological Process cellular response to unfolded protein involved_in IDA
GO:0034620 Biological Process cellular response to unfolded protein involved_in IMP
GO:0035924 Biological Process cellular response to vascular endothelial growth factor stimulus involved_in IDA
GO:0001935 Biological Process endothelial cell proliferation involved_in IDA
GO:1901142 Biological Process insulin metabolic process involved_in IDA
GO:0070059 Biological Process intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress involved_in IBA
GO:0070059 Biological Process intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress involved_in ISS
GO:0006402 Biological Process mRNA catabolic process involved_in TAS
GO:0070054 Biological Process mRNA splicing, via endonucleolytic cleavage and ligation involved_in IDA
GO:0070054 Biological Process mRNA splicing, via endonucleolytic cleavage and ligation involved_in IMP
GO:0070054 Biological Process mRNA splicing, via endonucleolytic cleavage and ligation involved_in TAS
GO:0036289 Biological Process peptidyl-serine autophosphorylation involved_in IDA
GO:1990579 Biological Process peptidyl-serine trans-autophosphorylation involved_in IMP
GO:0043507 Biological Process positive regulation of JUN kinase activity involved_in IDA
GO:0033120 Biological Process positive regulation of RNA splicing involved_in IDA
GO:1900103 Biological Process positive regulation of endoplasmic reticulum unfolded protein response involved_in IMP
GO:1904707 Biological Process positive regulation of vascular associated smooth muscle cell proliferation involved_in IMP
GO:0046777 Biological Process protein autophosphorylation involved_in IDA
GO:0006468 Biological Process protein phosphorylation involved_in IDA
GO:0016241 Biological Process regulation of macroautophagy involved_in TAS
GO:0034976 Biological Process response to endoplasmic reticulum stress involved_in IDA
GO:1990597 Cellular Component AIP1-IRE1 complex part_of IEA
GO:1990630 Cellular Component IRE1-RACK1-PP2A complex part_of IDA
GO:1990604 Cellular Component IRE1-TRAF2-ASK1 complex part_of IBA
GO:1990604 Cellular Component IRE1-TRAF2-ASK1 complex part_of IDA
GO:1990332 Cellular Component Ire1 complex part_of NAS
GO:0005737 Cellular Component cytoplasm located_in IDA
GO:0005783 Cellular Component endoplasmic reticulum located_in IDA
GO:0005789 Cellular Component endoplasmic reticulum membrane located_in IDA
GO:0005789 Cellular Component endoplasmic reticulum membrane located_in TAS
GO:0005739 Cellular Component mitochondrion located_in IEA
GO:0005637 Cellular Component nuclear inner membrane located_in IEA
Pathways
Name DB ID
Cellular responses to stress Reactome R-HSA-2262752
IRE1alpha activates chaperones Reactome R-HSA-381070
Unfolded Protein Response (UPR) Reactome R-HSA-381119
Cellular responses to stimuli Reactome R-HSA-8953897
Alzheimer's disease (WP5124) WikiPathways WP5124_r123917
Apoptosis-related network due to altered Notch3 in ovarian cancer (WP2864) WikiPathways WP2864_r108133
Endoplasmic reticulum stress response in coronavirus infection (WP4861) WikiPathways WP4861_r124658
Alzheimer's disease and miRNA effects (WP2059) WikiPathways WP2059_r119468
Corticotropin-releasing hormone signaling pathway (WP2355) WikiPathways WP2355_r120664
Roles of ceramides in the development of insulin resistance (WP5181) WikiPathways WP5181_r124468
Unfolded protein response (WP4925) WikiPathways WP4925_r123438
Nonalcoholic fatty liver disease (WP4396) WikiPathways WP4396_r123350
Photodynamic therapy-induced unfolded protein response (WP3613) WikiPathways WP3613_r106539
VEGFA-VEGFR2 signaling pathway (WP3888) WikiPathways WP3888_r116782
Transcripts
Accession Version MolecularType Name NCBI Comments
NM_001433 5 mRNA None NC_000017 Reference