ATF6

activating transcription factor 6
General Information
Name activating transcription factor 6
Alias
  • cyclic AMP-dependent transcription factor ATF-6 alpha
  • cAMP-dependent transcription factor ATF-6 alpha
Synonyms ATF6A ACHM7
Gene_family Basic leucine zipper proteins
organism Homo sapiens
entrez_id 22926
location 1q23.3
transcript_count 6
exon_count 17
Cross References
Location
by NCBI GRCh38.p14
    Summary
      Entrez This gene encodes a transcription factor that activates target genes for the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Although it is a transcription factor, this protein is unusual in that it is synthesized as a transmembrane protein that is embedded in the ER. It functions as an ER stress sensor/transducer, and following ER stress-induced proteolysis, it functions as a nuclear transcription factor via a cis-acting ER stress response element (ERSE) that is present in the promoters of genes encoding ER chaperones. This protein has been identified as a survival factor for quiescent but not proliferative squamous carcinoma cells. There have been conflicting reports about the association of polymorphisms in this gene with diabetes in different populations, but another polymorphism has been associated with increased plasma cholesterol levels. This gene is also thought to be a potential therapeutic target for cystic fibrosis. [provided by RefSeq, Aug 2011]
      Stringdb Cyclic AMP-dependent transcription factor ATF-6 alpha; Transmembrane glycoprotein of the endoplasmic reticulum that functions as a transcription activator and initiates the unfolded protein response (UPR) during endoplasmic reticulum stress. Cleaved upon ER stress, the N-terminal processed cyclic AMP-dependent transcription factor ATF-6 alpha translocates to the nucleus where it activates transcription of genes involved in the UPR. Binds DNA on the 5'-CCAC[GA]-3'half of the ER stress response element (ERSE) (5'-CCAAT-N(9)-CCAC[GA]-3') and of ERSE II (5'- ATTGG-N-CCACG-3'). Binding to E [...]
      nextProt Precursor of the transcription factor form (Processed cyclic AMP-dependent transcription factor ATF-6 alpha), which is embedded in the endoplasmic reticulum membrane (PubMed:10564271, PubMed:11158310, PubMed:11779464). Endoplasmic reticulum stress promotes processing of this form, releasing the transcription factor form that translocates into the nucleus, where it activates transcription of genes involved in the unfolded protein response (UPR) (PubMed:10564271, PubMed:11158310, PubMed:11779464).
    Interactions
    NCBI
    A A.Source B B.DB B.Source Description PubMed
    ATF6 BioGRID ORF3a GeneID BioGRID Proximity Label-MS
    ATF6 BioGRID E GeneID BioGRID Proximity Label-MS
    ATF6 BioGRID C9orf72 GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID UBASH3A GeneID BioGRID Two-hybrid
    ATF6 BioGRID TGOLN2 GeneID BioGRID Proximity Label-MS
    ATF6 BioGRID ORF1ab GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID ORF1ab GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
    ATF6 BioGRID CANX GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID RAB7A GeneID BioGRID Proximity Label-MS
    ATF6 BioGRID CDC42 GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID RNF168 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
    ATF6 BioGRID TMEM106B GeneID BioGRID Proximity Label-MS
    ATF6 BioGRID EIF2AK3 GeneID BioGRID Affinity Capture-Western
    ATF6 BioGRID RIPK2 GeneID BioGRID Affinity Capture-Western
    ATF6 BioGRID ERN1 GeneID BioGRID Affinity Capture-Western
    ATF6 BioGRID SOX2 GeneID BioGRID Affinity Capture-Western
    ATF6 BioGRID POU5F1 GeneID BioGRID Affinity Capture-Western
    ATF6 BioGRID CEBPD GeneID BioGRID Affinity Capture-Western
    ATF6 BioGRID NEDD8-MDP1 GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID ZYG11A GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID GPIHBP1 GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID CCDC107 GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID KCNG4 GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID STK40 GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID PCDH20 GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID COP1 GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID EDDM3B GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID SPPL2B GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID CYP26B1 GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID BTNL2 GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID PCDHAC1 GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID PCDHGA7 GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID PCDHGC5 GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID DET1 GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID ERLEC1 GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID FBXO2 GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID CD160 GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID LMAN2 GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID OS9 GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID BTNL3 GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID TRIB1 GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID CLEC3A GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID RARRES1 GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID PIGH GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID PDE3A GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID KCNC3 GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID IL7 GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID IGHG4 GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID IGHG2 GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID HLA-DQA1 GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID GABRD GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID FHL3 GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID CHRNB1 GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID CDH5 GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID DERL1 GeneID BioGRID Proximity Label-MS
    ATF6 BioGRID ELOVL5 GeneID BioGRID Proximity Label-MS
    ATF6 BioGRID LRRC59 GeneID BioGRID Proximity Label-MS
    ATF6 BioGRID HSD17B11 GeneID BioGRID Proximity Label-MS
    ATF6 BioGRID FBXO6 GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID TMT1A GeneID BioGRID Proximity Label-MS
    ATF6 BioGRID RNF139 GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID SEC62 GeneID BioGRID Proximity Label-MS
    ATF6 BioGRID STX4 GeneID BioGRID Proximity Label-MS
    ATF6 BioGRID STIM1 GeneID BioGRID Proximity Label-MS
    ATF6 BioGRID SSR1 GeneID BioGRID Proximity Label-MS
    ATF6 BioGRID RPN1 GeneID BioGRID Proximity Label-MS
    ATF6 BioGRID PEX14 GeneID BioGRID Proximity Label-MS
    ATF6 BioGRID EMD GeneID BioGRID Proximity Label-MS
    ATF6 BioGRID DNAJC25 GeneID BioGRID Proximity Label-MS
    ATF6 BioGRID DNAJC1 GeneID BioGRID Proximity Label-MS
    ATF6 BioGRID DNAJC16 GeneID BioGRID Proximity Label-MS
    ATF6 BioGRID SEC63 GeneID BioGRID Proximity Label-MS
    ATF6 BioGRID MAGI1 GeneID BioGRID Affinity Capture-Western; Two-hybrid
    ATF6 BioGRID Magi1 GeneID BioGRID Two-hybrid
    ATF6 BioGRID FKBP8 GeneID BioGRID Proximity Label-MS
    ATF6 BioGRID ST7 GeneID BioGRID Proximity Label-MS
    ATF6 BioGRID ORF8a GeneID BioGRID Affinity Capture-Western; Co-localization
    ATF6 BioGRID LMBR1L GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID LDHA GeneID BioGRID Co-fractionation
    ATF6 BioGRID EPHX2 GeneID BioGRID Co-fractionation
    ATF6 BioGRID HIBADH GeneID BioGRID Co-fractionation
    ATF6 BioGRID ACAA2 GeneID BioGRID Co-fractionation
    ATF6 BioGRID SPARC GeneID BioGRID Co-fractionation
    ATF6 BioGRID CSK GeneID BioGRID Synthetic Lethality
    ATF6 BioGRID PTRH2 GeneID BioGRID Proximity Label-MS
    ATF6 BioGRID DAPK1 GeneID BioGRID Reconstituted Complex
    ATF6 BioGRID RNF4 GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID HNRNPL GeneID BioGRID Affinity Capture-RNA
    ATF6 BioGRID TRIM25 GeneID BioGRID Affinity Capture-RNA
    ATF6 BioGRID CD300E GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID PCDHB16 GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID PCDHB11 GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID CLEC2D GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID MGAT4C GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID LRRN2 GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID HLA-E GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID SH3TC1 GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID PARG GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID APOD GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID ACLY GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID UBC GeneID BioGRID Affinity Capture-MS
    ATF6 BioGRID MAPK14 GeneID BioGRID Affinity Capture-Western
    ATF6 BioGRID ATF6 GeneID BioGRID FRET; Two-hybrid
    ATF6 BioGRID XBP1 GeneID BioGRID FRET
    ATF6 BioGRID NNMT GeneID BioGRID Two-hybrid
    ATF6 BioGRID DDC GeneID BioGRID Two-hybrid
    ATF6 BioGRID BPGM GeneID BioGRID Two-hybrid
    ATF6 BioGRID TNFRSF1A GeneID BioGRID Two-hybrid
    ATF6 BioGRID APP GeneID BioGRID Reconstituted Complex
    ATF6 BioGRID SP1 GeneID BioGRID Phenotypic Enhancement
    ATF6 BioGRID SYVN1 GeneID BioGRID Affinity Capture-Western
    ATF6 BioGRID WFS1 GeneID BioGRID Affinity Capture-Western
    ATF6 BioGRID SREBF2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    ATF6 BioGRID YY1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    ATF6 BioGRID NFYC GeneID BioGRID Reconstituted Complex; Two-hybrid
    ATF6 BioGRID CREB1 GeneID BioGRID Two-hybrid
    ATF6 Protein CREB3L3 GeneID HPRD None
    ATF6 Protein ATF6 GeneID HPRD None
    ATF6 Protein NFYC GeneID HPRD None
    ATF6 Protein GTF2I GeneID HPRD None
    ATF6 Protein ATF6B GeneID HPRD None
    ATF6 Protein SRF GeneID HPRD None
    ATF6 Protein YY1 GeneID HPRD None
    ATF6 BioGRID SRF GeneID BioGRID Reconstituted Complex; Two-hybrid
    ATF6 BioGRID NFYA GeneID BioGRID Two-hybrid
    ATF6 BioGRID GTF2I GeneID BioGRID Affinity Capture-Western
    ATF6 BioGRID ATF6B GeneID BioGRID Two-hybrid
    StringDB
    A B experiments database textmining combined score hadb nhadb
    ATF6 AGPAT3 0 0 45 150 1 1
    ATF6 CANX 0 0 680 762 1 2
    ATF6 TXN 0 0 334 346 1 1
    ATF6 NPHS2 0 0 150 260 1 1
    ATF6 FAF2 0 0 430 430 1 1
    ATF6 CAST 0 0 160 159 1 1
    ATF6 HRK 0 0 206 206 1 1
    ATF6 CDIPT 0 0 90 246 1 1
    ATF6 VPS41 0 0 0 217 1 1
    ATF6 SPINK1 0 0 120 192 1 1
    ATF6 CAT 0 0 414 421 1 1
    ATF6 CIZ1 0 0 0 223 1 1
    ATF6 LDLR 0 0 193 193 1 1
    ATF6 GNB2L1 0 0 154 153 1 1
    ATF6 DCLK2 0 0 0 175 1 1
    ATF6 ATP2A2 0 0 260 355 1 1
    ATF6 SSR3 0 0 111 166 1 1
    ATF6 KLF9 0 0 95 308 1 1
    ATF6 DNAJB2 0 0 150 183 1 1
    ATF6 HPRT1 0 0 188 188 1 1
    ATF6 RNASEL 0 0 181 218 1 1
    ATF6 HINFP 0 0 47 299 1 1
    ATF6 DDIT4 0 0 283 291 1 1
    ATF6 RHEB 0 0 270 301 1 2
    ATF6 SMN2 0 0 53 266 1 1
    ATF6 ATF7 0 0 255 291 1 1
    ATF6 BAK1 0 0 182 182 1 2
    ATF6 NCF1 0 0 180 179 1 1
    ATF6 QSOX1 0 0 81 247 1 1
    ATF6 PSIP1 0 0 45 177 1 1
    ATF6 STIM1 0 0 194 195 1 2
    ATF6 ALG12 0 0 142 168 1 1
    ATF6 STX2 0 0 150 214 1 1
    ATF6 BCL2L2 0 0 165 165 1 1
    ATF6 CCND1 0 0 321 321 1 1
    ATF6 SREBF2 270 0 629 848 1 1
    ATF6 APEH 0 0 183 200 1 1
    ATF6 SRPR 0 0 71 439 1 1
    ATF6 TBC1D20 0 0 0 290 1 1
    ATF6 STAR 0 0 123 151 1 1
    ATF6 JUND 0 0 120 269 1 1
    ATF6 TMEM38A 0 0 92 192 1 1
    ATF6 NOS3 0 0 281 281 1 1
    ATF6 HLA-E 274 0 0 274 1 1
    ATF6 HGNC:9982 0 0 108 310 1 1
    ATF6 RPS6KB1 0 0 368 420 1 2
    ATF6 RFWD2 94 0 52 157 1 1
    ATF6 CNGB3 0 0 380 411 1 1
    ATF6 SRP68 0 0 103 461 1 1
    ATF6 CEP350 0 0 46 237 1 1
    ATF6 LEPREL2 0 0 154 153 1 1
    ATF6 CDK1 0 0 142 165 1 1
    ATF6 EIF4E 0 0 243 265 1 1
    ATF6 HMGCR 0 0 203 284 1 1
    ATF6 LOX 0 0 158 157 1 1
    ATF6 HSPA9 0 0 347 385 1 1
    ATF6 SGK1 0 0 122 176 1 1
    ATF6 IRS1 0 0 404 415 1 1
    ATF6 EPHB1 0 0 0 154 1 1
    ATF6 EPHB4 0 0 0 151 1 1
    ATF6 GADD45A 0 0 233 232 1 1
    ATF6 SRPRB 0 0 112 463 1 1
    ATF6 ATF3 0 0 603 711 1 1
    ATF6 CDH5 129 0 90 191 1 1
    ATF6 UVRAG 0 0 255 272 1 2
    ATF6 PARP3 0 0 0 166 1 1
    ATF6 APOB 0 0 232 249 1 1
    ATF6 IGF1 0 0 254 255 1 1
    ATF6 MAPK1 0 0 114 184 1 2
    ATF6 THBS2 0 0 51 216 1 1
    ATF6 EZH1 0 0 0 223 1 1
    ATF6 ASB11 0 0 74 150 1 1
    ATF6 MAP3K14 0 0 297 297 1 1
    ATF6 RPS6KA2 0 0 89 151 1 1
    ATF6 SRP54 0 0 66 436 1 1
    ATF6 GCG 0 0 271 276 1 1
    ATF6 ATG4B 0 0 203 203 1 2
    ATF6 NFKB2 0 0 108 182 1 1
    ATF6 EDEM1 0 0 687 728 1 2
    ATF6 UBE2J1 0 0 384 384 1 1
    ATF6 DRAM1 0 0 193 200 1 2
    ATF6 SDF2L1 0 0 261 319 1 1
    ATF6 NFE2L3 0 0 150 224 1 1
    ATF6 BCAP31 0 0 323 331 1 1
    ATF6 RAB7A 0 0 181 181 1 2
    ATF6 PRDX4 0 0 204 204 1 1
    ATF6 FGF2 0 0 210 210 1 1
    ATF6 THRSP 0 0 64 178 1 1
    ATF6 TXNIP 0 0 375 384 1 1
    ATF6 CSNK2A1 0 0 0 157 1 1
    ATF6 ADM2 0 0 134 167 1 1
    ATF6 VCL 0 0 122 216 1 1
    ATF6 RP1 0 0 0 166 1 1
    ATF6 ATP13A2 0 0 67 486 1 2
    ATF6 APH1B 0 0 326 325 1 1
    ATF6 RCAN1 0 0 195 196 1 2
    ATF6 FIS1 0 0 195 273 1 2
    ATF6 OSBP2 0 0 48 496 1 1
    ATF6 ERCC3 0 0 0 171 1 1
    ATF6 EAPP 0 0 88 297 1 1
    ATF6 CNGA2 0 0 0 206 1 1
    ATF6 CLSTN1 0 0 0 348 1 1
    ATF6 CKAP4 0 0 123 211 1 1
    ATF6 SLC7A11 0 0 193 198 1 1
    ATF6 RBFOX3 0 0 181 181 1 1
    ATF6 CBSL 0 0 181 181 1 1
    ATF6 EEF2 0 0 142 164 1 1
    ATF6 USP14 0 0 118 210 1 1
    ATF6 RPLP0 0 0 170 169 1 1
    ATF6 STT3B 0 0 98 257 1 1
    ATF6 PPP1R15A 0 0 759 841 1 2
    ATF6 SIPA1 0 0 81 175 1 1
    ATF6 MGAT4C 223 0 0 223 1 1
    ATF6 PTRH2 378 0 0 378 1 1
    ATF6 LHX9 0 0 0 384 1 1
    ATF6 NBR1 0 0 181 198 1 2
    ATF6 RNF4 270 0 0 270 1 1
    ATF6 TNF 0 0 460 492 1 1
    ATF6 NFYC 409 0 113 463 1 1
    ATF6 HSPA2 0 0 67 184 1 1
    ATF6 C22orf29 0 0 340 340 1 1
    ATF6 BDNF 0 0 231 245 1 2
    ATF6 CD44 0 0 96 178 1 1
    ATF6 VAPB 0 800 456 896 1 1
    ATF6 PIK3R2 0 0 321 321 1 1
    ATF6 CASP2 0 0 405 441 1 1
    ATF6 UNC13A 0 0 0 169 1 1
    ATF6 CALR3 0 0 46 192 1 1
    ATF6 CREB3L4 0 0 556 276 1 1
    ATF6 WSB1 0 0 54 219 1 1
    ATF6 TDRD5 0 0 45 161 1 1
    ATF6 DUOX1 0 0 155 154 1 1
    ATF6 IKBKB 0 0 252 261 1 1
    ATF6 NOX4 0 0 310 309 1 1
    ATF6 ARF4 0 0 147 197 1 1
    ATF6 LGR6 0 0 0 208 1 1
    ATF6 RUNX2 0 0 689 689 1 1
    ATF6 ATP13A3 0 0 0 472 1 1
    ATF6 CEBPG 0 0 138 457 1 1
    ATF6 EDF1 0 0 0 254 1 1
    ATF6 PPP2R4 0 0 167 167 1 1
    ATF6 ASNS 0 0 387 458 1 1
    ATF6 XIAP 0 0 271 294 1 1
    ATF6 PPARG 0 0 341 365 1 1
    ATF6 MARCH6 0 0 181 181 1 1
    ATF6 CAPN1 0 0 218 235 1 2
    ATF6 CPT1A 0 0 180 191 1 1
    ATF6 AKT1 0 0 557 589 1 2
    ATF6 ST8SIA4 0 0 166 167 1 1
    ATF6 ERP29 0 0 379 379 1 1
    ATF6 CLPP 0 0 157 166 1 1
    ATF6 PARP4 0 0 0 166 1 1
    ATF6 CPE 0 0 150 199 1 1
    ATF6 FAS 0 0 202 202 1 2
    ATF6 SUMO1 0 0 108 158 1 1
    ATF6 PRDM16 0 0 95 202 1 1
    ATF6 MAP3K15 0 0 0 156 1 1
    ATF6 VCAM1 0 0 194 194 1 1
    ATF6 ATF4 0 0 830 904 1 2
    ATF6 HSPH1 0 0 108 172 1 1
    ATF6 DERL2 0 0 413 465 1 1
    ATF6 CD4 0 0 203 203 1 1
    ATF6 MBTPS1 0 900 710 972 1 1
    ATF6 ATP2A3 0 0 124 228 1 1
    ATF6 MAFK 0 0 82 219 1 1
    ATF6 VLDLR 0 0 138 161 1 1
    ATF6 CREM 0 0 157 254 1 1
    ATF6 IRF3 0 0 232 231 1 1
    ATF6 GIGYF1 0 0 0 167 1 1
    ATF6 YIPF5 0 0 346 354 1 1
    ATF6 ERBB2 0 0 170 188 1 2
    ATF6 ENSG00000274276 0 0 181 181 1 1
    ATF6 CSNK2A3 0 0 0 157 1 1
    ATF6 NGF 0 0 184 253 1 1
    ATF6 TH 0 0 143 166 1 1
    ATF6 BBC3 0 0 324 323 1 1
    ATF6 ERGIC1 0 0 0 189 1 1
    ATF6 GPT 0 0 290 290 1 1
    ATF6 CLGN 0 0 0 279 1 1
    ATF6 RDH16 0 0 46 154 1 1
    ATF6 UBQLN1 0 0 88 190 1 2
    ATF6 PINK1 0 0 287 310 1 2
    ATF6 ASPG 0 0 150 203 1 1
    ATF6 HSP90AB1 0 0 66 312 1 2
    ATF6 CXCL10 0 0 157 156 1 1
    ATF6 MAFG 0 0 134 264 1 1
    ATF6 RTN4 0 0 268 268 1 1
    ATF6 EIF4EBP1 0 0 339 339 1 1
    ATF6 DNAJB1 0 0 456 457 1 2
    ATF6 MAN1C1 0 0 73 150 1 1
    ATF6 ATG3 0 0 337 337 1 2
    ATF6 DNAJB11 0 0 469 492 1 1
    ATF6 HOXB6 0 0 63 205 1 1
    ATF6 TLR3 0 0 181 181 1 1
    ATF6 TCL1A 0 0 386 386 1 1
    ATF6 TASP1 0 0 0 190 1 1
    ATF6 HNF4A 0 0 155 167 1 1
    ATF6 EIF2AK3 0 0 900 924 1 2
    ATF6 RNF139 0 0 203 252 1 1
    ATF6 TP53INP1 0 0 137 187 1 2
    ATF6 RTN3 0 0 184 183 1 1
    ATF6 PLOD3 0 0 90 229 1 1
    ATF6 ACLY 130 0 149 227 1 1
    ATF6 DGAT2 0 0 244 264 1 1
    ATF6 BGLAP 0 0 171 171 1 1
    ATF6 MCU 0 0 181 181 1 1
    ATF6 WDR72 0 0 0 217 1 1
    ATF6 ACIN1 0 0 49 308 1 1
    ATF6 FOXO3 0 0 247 308 1 2
    ATF6 VDAC3 0 0 126 167 1 1
    ATF6 SLC2A4 0 0 236 236 1 1
    ATF6 APOE 0 0 284 284 1 1
    ATF6 SCD 0 0 325 330 1 1
    ATF6 VIMP 0 0 242 241 1 1
    ATF6 SRC 0 0 233 249 1 1
    ATF6 EPHB3 0 0 0 154 1 1
    ATF6 CRTC1 0 0 90 218 1 1
    ATF6 PCDHB16 185 0 0 202 1 1
    ATF6 F2R 0 0 350 355 1 1
    ATF6 BNIP3L 0 0 195 195 1 2
    ATF6 NARFL 0 0 0 281 1 1
    ATF6 TGFB1 0 0 81 164 1 1
    ATF6 VDAC1 0 0 283 282 1 2
    ATF6 TSC2 0 0 282 282 1 2
    ATF6 RAB7B 0 0 182 181 1 1
    ATF6 TRRAP 0 0 0 214 1 1
    ATF6 STAT5B 0 0 74 167 1 1
    ATF6 ZFYVE1 0 0 150 229 1 2
    ATF6 RIPK3 0 0 134 172 1 1
    ATF6 UPF3B 0 0 134 193 1 1
    ATF6 PRKCD 0 0 166 203 1 2
    ATF6 UBR1 0 0 414 428 1 1
    ATF6 DIO2 0 0 90 187 1 1
    ATF6 MLF1 0 0 71 231 1 1
    ATF6 MGST1 0 0 0 207 1 1
    ATF6 HMOX1 0 0 416 416 1 2
    ATF6 DCX 0 0 0 166 1 1
    ATF6 CCDC88B 0 0 188 188 1 1
    ATF6 TBK1 0 0 120 150 1 2
    ATF6 SEC13 0 0 145 271 1 1
    ATF6 TOMM20 0 0 181 181 1 1
    ATF6 YY1 486 0 698 855 1 1
    ATF6 ATF6B 192 800 743 860 1 1
    ATF6 IARS 0 0 127 151 1 1
    ATF6 EIF2S1 0 0 857 905 1 2
    ATF6 EPHA5 0 0 0 154 1 1
    ATF6 PSMB9 0 0 113 176 1 1
    ATF6 PTGS2 0 0 245 254 1 1
    ATF6 KCNIP1 0 0 279 279 1 1
    ATF6 NQO1 0 0 261 261 1 1
    ATF6 CASP3 0 0 681 713 1 2
    ATF6 PDIA6 0 0 536 544 1 1
    ATF6 TMEM259 0 0 90 185 1 1
    ATF6 REL 0 0 170 188 1 1
    ATF6 HSPB8 0 0 155 154 1 2
    ATF6 ATG101 0 0 182 181 1 2
    ATF6 OS9 131 0 398 454 1 1
    ATF6 NLRP3 0 0 334 334 1 2
    ATF6 HSPA1B 0 0 82 190 1 1
    ATF6 PSMB6 0 0 124 152 1 1
    ATF6 PCDHAC1 185 0 0 202 1 1
    ATF6 CEBPZ 0 0 323 323 1 1
    ATF6 APCS 0 0 293 293 1 1
    ATF6 HNRNPL 270 0 0 270 1 1
    ATF6 CXCL1 0 0 141 174 1 1
    ATF6 TMEM38B 0 0 167 319 1 1
    ATF6 ATG4D 0 0 144 175 1 2
    ATF6 GFPT1 0 0 134 184 1 1
    ATF6 TRIB3 0 0 469 487 1 1
    ATF6 NR2C2 0 0 0 207 1 1
    ATF6 GDF11 0 0 0 165 1 1
    ATF6 CYBB 0 0 324 323 1 1
    ATF6 RAD21 0 0 0 763 1 1
    ATF6 BHLHA15 0 0 438 462 1 1
    ATF6 ATG12 0 0 459 492 1 2
    ATF6 KDELR3 0 0 134 268 1 1
    ATF6 TNFRSF10B 0 0 505 533 1 1
    ATF6 IHH 0 0 161 161 1 1
    ATF6 HSPA4L 0 0 161 210 1 1
    ATF6 DCDC2 0 0 0 166 1 1
    ATF6 PDE6C 0 0 374 440 1 1
    ATF6 CUL3 0 0 134 193 1 1
    ATF6 CHUK 0 0 138 171 1 1
    ATF6 EPHB2 0 0 0 154 1 2
    ATF6 UNC119 0 0 134 221 1 1
    ATF6 INSRR 0 0 0 150 1 1
    ATF6 NTF3 0 0 51 195 1 1
    ATF6 NPLOC4 0 0 207 207 1 1
    ATF6 GPX8 0 0 70 167 1 1
    ATF6 GSK3B 0 0 193 270 1 2
    ATF6 TTR 0 0 125 157 1 2
    ATF6 CASP4 0 0 594 631 1 2
    ATF6 CDKN2A 0 0 140 158 1 2
    ATF6 EPHA3 0 0 0 154 1 1
    ATF6 UNC13B 0 0 92 213 1 1
    ATF6 PRDM1 0 0 108 169 1 1
    ATF6 HDAC1 0 0 418 418 1 2
    ATF6 RIPK1 0 0 249 267 1 1
    ATF6 ERO1LB 0 0 459 507 1 1
    ATF6 CRYAB 0 0 107 182 1 1
    ATF6 ATG16L1 0 0 358 358 1 2
    ATF6 TXNRD1 0 0 181 204 1 1
    ATF6 CEBPB 0 0 423 781 1 1
    ATF6 SMPD1 0 0 170 169 1 1
    ATF6 MEF2A 0 0 90 248 1 1
    ATF6 TG 0 0 150 174 1 1
    ATF6 PKP3 0 0 0 241 1 1
    ATF6 NOD2 0 0 413 413 1 1
    ATF6 PDIA4 0 0 600 644 1 1
    ATF6 GPR26 0 0 0 175 1 1
    ATF6 HM13 0 0 101 265 1 1
    ATF6 RRAGC 0 0 49 259 1 1
    ATF6 MSTN 0 0 45 169 1 1
    ATF6 PKP4 0 0 0 460 1 1
    ATF6 SRP14 0 0 0 219 1 1
    ATF6 RXRA 0 0 53 319 1 1
    ATF6 STAT5A 0 0 93 184 1 1
    ATF6 PITRM1 0 0 0 809 1 1
    ATF6 TTLL5 0 0 97 258 1 1
    ATF6 SOCS3 0 0 157 156 1 1
    ATF6 FOS 0 0 284 310 1 1
    ATF6 FASLG 0 0 216 216 1 1
    ATF6 MAN2B1 0 0 0 256 1 1
    ATF6 GPX2 0 0 160 166 1 1
    ATF6 SOD2 0 0 256 256 1 1
    ATF6 KRAS 0 0 123 201 1 1
    ATF6 FOXO1 0 0 295 305 1 2
    ATF6 EPAS1 0 0 95 162 1 2
    ATF6 CNGA3 0 0 370 371 1 1
    ATF6 TSPAN2 0 0 0 189 1 1
    ATF6 EIF4A2 0 0 127 260 1 1
    ATF6 HSPA5 270 800 990 999 1 2
    ATF6 PKP1 0 0 0 241 1 1
    ATF6 UPF1 0 0 142 254 1 1
    ATF6 ARMC2 0 0 0 241 1 1
    ATF6 WARS 0 0 164 163 1 1
    ATF6 MET 0 0 91 171 1 1
    ATF6 ATXN3 0 0 175 193 1 1
    ATF6 LRRK2 0 0 180 200 1 2
    ATF6 APH1A 0 0 266 266 1 1
    ATF6 DNAJC10 0 0 411 424 1 1
    ATF6 CERS6 0 0 298 298 1 1
    ATF6 TLR2 0 0 247 250 1 1
    ATF6 PMAIP1 0 0 456 456 1 1
    ATF6 MAPK11 0 900 61 919 1 1
    ATF6 NRL 0 0 81 183 1 1
    ATF6 STT3A 0 0 163 215 1 1
    ATF6 PRKCSH 0 0 143 276 1 1
    ATF6 PSENEN 0 0 290 290 1 1
    ATF6 DERL1 0 0 374 428 1 1
    ATF6 SDC1 0 0 150 190 1 1
    ATF6 THBS1 0 0 82 265 1 1
    ATF6 TMBIM1 0 0 75 279 1 1
    ATF6 FAM91A1 0 0 0 183 1 1
    ATF6 MAPT 0 0 167 167 1 2
    ATF6 BECN1 0 0 565 628 1 2
    ATF6 PDIA3 0 0 518 648 1 1
    ATF6 MAN2A2 0 0 0 275 1 1
    ATF6 DNAJB9 0 0 681 702 1 2
    ATF6 THBS3 0 0 57 266 1 1
    ATF6 RXRB 0 0 0 381 1 1
    ATF6 NOD1 0 0 150 168 1 1
    ATF6 GNAI3 0 0 48 161 1 2
    ATF6 SIGMAR1 0 0 403 413 1 1
    ATF6 PSMD2 0 0 124 155 1 1
    ATF6 ORMDL1 0 0 184 219 1 1
    ATF6 CDC25A 0 0 72 292 1 1
    ATF6 SEC62 0 0 242 448 1 1
    ATF6 RRAGD 0 0 57 429 1 1
    ATF6 SELO 0 0 63 158 1 1
    ATF6 PARP2 0 0 0 231 1 1
    ATF6 TRIP6 0 0 0 206 1 1
    ATF6 LGR5 0 0 81 319 1 1
    ATF6 TOR1AIP1 0 0 97 293 1 1
    ATF6 ATG5 0 0 556 633 1 2
    ATF6 TTC13 0 0 0 195 1 1
    ATF6 UGGT1 0 0 260 373 1 1
    ATF6 FUS 0 0 182 181 1 1
    ATF6 PTPN1 0 0 294 302 1 1
    ATF6 MANF 0 0 519 562 1 1
    ATF6 IRF1 0 0 166 165 1 1
    ATF6 HIPK2 0 0 66 232 1 1
    ATF6 PDIA5 0 0 243 359 1 1
    ATF6 UGGT2 0 0 81 186 1 1
    ATF6 XBP1 458 900 939 998 1 2
    ATF6 ZCCHC4 0 0 81 266 1 1
    ATF6 PLIN2 0 0 150 203 1 1
    ATF6 PDZRN3 0 0 0 206 1 1
    ATF6 SIRT1 0 0 343 343 1 2
    ATF6 ST8SIA2 0 0 211 224 1 1
    ATF6 MCL1 0 0 457 468 1 2
    ATF6 OSBP 0 0 72 316 1 1
    ATF6 ACOX1 0 0 139 195 1 1
    ATF6 CTSB 0 0 216 216 1 2
    ATF6 LMNB1 0 0 156 157 1 1
    ATF6 NOX1 0 0 155 154 1 1
    ATF6 HMGB1 0 0 181 190 1 2
    ATF6 TXNDC5 0 0 245 259 1 1
    ATF6 ACBD3 0 0 170 169 1 1
    ATF6 IFNB1 0 0 264 264 1 1
    ATF6 PPP1CA 0 0 124 164 1 1
    ATF6 TOR3A 0 0 65 234 1 1
    ATF6 ESR1 0 0 282 302 1 1
    ATF6 UBQLN2 0 0 181 223 1 2
    ATF6 OPTN 0 0 175 187 1 2
    ATF6 MAP3K5 0 0 637 680 1 1
    ATF6 RGS1 0 0 121 181 1 1
    ATF6 BACE1 0 0 184 185 1 1
    ATF6 ULK1 0 0 325 325 1 2
    ATF6 TENM3 0 0 0 156 1 1
    ATF6 CDC25B 0 0 57 280 1 1
    ATF6 KLF16 0 0 0 199 1 1
    ATF6 DNAJC15 0 0 57 219 1 1
    ATF6 RPS6KA1 0 0 123 183 1 1
    ATF6 RPS18 0 0 58 648 1 1
    ATF6 SEL1L 0 0 456 589 1 1
    ATF6 NUCB1 0 0 143 201 1 1
    ATF6 CTNNA2 0 0 0 651 1 1
    ATF6 SEC61B 0 0 193 273 1 1
    ATF6 FN1 0 0 201 201 1 1
    ATF6 TBP 0 0 202 213 1 1
    ATF6 GPX1 0 0 194 210 1 1
    ATF6 SURF4 0 0 112 157 1 1
    ATF6 RARA 0 0 95 243 1 1
    ATF6 IKBKG 0 0 162 253 1 1
    ATF6 HSPB1 0 0 328 328 1 1
    ATF6 CLSTN2 0 0 0 348 1 1
    ATF6 HSPB2 0 0 325 325 1 1
    ATF6 ATG10 0 0 281 286 1 2
    ATF6 RT14 0 0 206 224 1 1
    ATF6 ALPK3 0 0 165 165 1 1
    ATF6 SMG6 0 0 146 196 1 1
    ATF6 CNGA4 0 0 0 205 1 1
    ATF6 EIF2A 0 0 556 674 1 1
    ATF6 MATN3 0 0 178 207 1 1
    ATF6 MAP1LC3B 0 0 517 547 1 2
    ATF6 FOSL2 0 0 117 178 1 1
    ATF6 GDF15 0 0 181 200 1 1
    ATF6 DLG4 0 0 134 161 1 1
    ATF6 NR1H4 0 0 194 217 1 1
    ATF6 FAIM2 0 0 0 231 1 1
    ATF6 ACTG1 0 0 150 203 1 1
    ATF6 RXRG 0 0 66 251 1 1
    ATF6 ATG7 0 0 469 522 1 2
    ATF6 PPP1R15B 0 0 342 370 1 1
    ATF6 PPARGC1B 0 0 74 321 1 1
    ATF6 COL1A1 0 0 141 171 1 1
    ATF6 DERL3 0 0 501 545 1 1
    ATF6 RBPJ 0 0 75 293 1 1
    ATF6 GFAP 0 0 170 169 1 2
    ATF6 HHEX 0 0 64 161 1 1
    ATF6 PSMB7 0 0 117 172 1 1
    ATF6 ARVCF 0 0 0 466 1 1
    ATF6 IL10 0 0 257 277 1 1
    ATF6 ATM 0 0 213 231 1 1
    ATF6 COL4A3BP 0 0 138 188 1 1
    ATF6 CEPT1 0 0 108 151 1 1
    ATF6 PREB 0 0 112 152 1 1
    ATF6 PON2 0 0 126 166 1 1
    ATF6 CTSD 0 0 230 229 1 2
    ATF6 TXNDC12 0 0 442 442 1 1
    ATF6 OGT 0 0 306 469 1 1
    ATF6 PARP16 0 0 182 181 1 1
    ATF6 MAN1A2 0 0 65 241 1 1
    ATF6 NFE2L1 0 0 249 328 1 1
    ATF6 NFKBIA 0 0 284 301 1 1
    ATF6 RTCB 0 0 283 349 1 1
    ATF6 LEP 0 0 320 329 1 1
    ATF6 TCF4 0 0 292 324 1 1
    ATF6 ORMDL2 0 0 155 188 1 1
    ATF6 LDHA 128 0 74 351 1 1
    ATF6 AMBRA1 0 0 170 189 1 2
    ATF6 RARB 0 0 0 382 1 1
    ATF6 MAPK10 0 0 170 194 1 2
    ATF6 BAG1 0 0 156 155 1 2
    ATF6 FAM134B 0 0 212 212 1 1
    ATF6 UCP1 0 0 167 167 1 1
    ATF6 FKBP2 0 0 176 175 1 1
    ATF6 SREBF1 0 0 506 652 1 2
    ATF6 WSB2 0 0 0 209 1 1
    ATF6 DNAJC1 0 0 212 241 1 1
    ATF6 RABGGTA 0 0 0 261 1 1
    ATF6 MAPK14 270 900 203 954 1 1
    ATF6 PTEN 0 0 262 301 1 2
    ATF6 SRP9 0 0 64 315 1 1
    ATF6 VEGFA 0 0 369 369 1 1
    ATF6 FSD1L 0 0 227 411 1 1
    ATF6 MAPK7 0 0 124 194 1 1
    ATF6 TENM1 0 0 0 156 1 1
    ATF6 SEC24A 0 0 281 314 1 1
    ATF6 SIL1 0 0 294 299 1 1
    ATF6 WIPI1 0 0 210 289 1 2
    ATF6 TMEM86A 0 0 0 189 1 1
    ATF6 DNM1L 0 0 218 218 1 2
    ATF6 GAPDHS 0 0 42 206 1 1
    ATF6 DDAH2 0 0 0 252 1 1
    ATF6 EZH2 0 0 74 160 1 1
    ATF6 STAT3 0 0 342 343 1 2
    ATF6 PRRT4 0 0 0 154 1 1
    ATF6 GDNF 0 0 181 181 1 1
    ATF6 EIF2AK4 0 0 547 616 1 1
    ATF6 GCLM 0 0 217 234 1 1
    ATF6 SERPINH1 0 0 295 307 1 1
    ATF6 CHRFAM7A 0 0 0 369 1 1
    ATF6 ERN1 0 0 915 934 1 2
    ATF6 SFTPC 0 0 160 159 1 1
    ATF6 CISD2 0 0 139 161 1 2
    ATF6 AGR2 0 0 241 257 1 1
    ATF6 CYBA 0 0 138 156 1 1
    ATF6 CAMKK2 0 0 150 200 1 2
    ATF6 MAFA 0 0 122 219 1 1
    ATF6 HDAC6 0 0 210 210 1 2
    ATF6 APAF1 0 0 343 366 1 1
    ATF6 SKIV2L 0 0 95 175 1 1
    ATF6 DNAJA1 0 0 122 158 1 1
    ATF6 MAP1A 0 0 233 232 1 1
    ATF6 ORAI1 0 0 138 156 1 1
    ATF6 DDIT3 0 900 870 989 1 2
    ATF6 LPP 0 0 0 206 1 1
    ATF6 TTLL10 0 0 95 256 1 1
    ATF6 PDZD4 0 0 0 173 1 1
    ATF6 RMDN3 0 0 161 161 1 1
    ATF6 LMNA 0 0 204 204 1 1
    ATF6 SLC2A2 0 0 150 181 1 1
    ATF6 PPP1CC 0 0 208 293 1 1
    ATF6 MYD88 0 0 186 229 1 1
    ATF6 HTT 0 0 309 330 1 1
    ATF6 EGFR 0 0 270 287 1 1
    ATF6 CFLAR 0 0 219 224 1 1
    ATF6 CDK4 0 0 181 181 1 1
    ATF6 ATP2C1 0 0 101 177 1 1
    ATF6 ANKFY1 0 0 0 268 1 1
    ATF6 SLC2A1 0 0 160 159 1 1
    ATF6 PRRT3 0 0 0 183 1 1
    ATF6 LAMP1 0 0 166 199 1 2
    ATF6 ASB7 0 0 82 274 1 1
    ATF6 FADD 0 0 263 269 1 2
    ATF6 HMGCS1 0 0 194 446 1 1
    ATF6 ENSG00000273637 0 0 0 252 1 1
    ATF6 CFTR 0 0 293 293 1 1
    ATF6 INSIG1 0 0 254 264 1 1
    ATF6 CREBZF 0 0 212 212 1 1
    ATF6 CTNNA1 0 0 0 651 1 1
    ATF6 TP53 0 0 464 474 1 2
    ATF6 MDM2 0 0 187 204 1 1
    ATF6 PPIF 0 0 167 167 1 1
    ATF6 MAP2K1 0 0 166 165 1 1
    ATF6 CNGB1 0 0 0 205 1 1
    ATF6 FURIN 0 0 164 293 1 1
    ATF6 CHAC1 0 0 341 357 1 1
    ATF6 HNRNPU 0 0 0 188 1 1
    ATF6 SEC24C 0 0 107 180 1 1
    ATF6 STK11 0 0 180 179 1 2
    ATF6 FKBP11 0 0 143 183 1 1
    ATF6 CTNND2 0 0 0 460 1 1
    ATF6 LMBR1L 270 0 0 270 1 1
    ATF6 AKT2 0 0 123 186 1 1
    ATF6 TDGF1 0 0 142 179 1 1
    ATF6 RB1CC1 0 0 293 305 1 2
    ATF6 NHLRC2 0 0 0 187 1 1
    ATF6 NFE2L2 0 0 452 461 1 1
    ATF6 ATP13A5 0 0 0 241 1 1
    ATF6 DRG2 0 0 57 244 1 1
    ATF6 EFNA5 0 0 96 223 1 1
    ATF6 PARK7 0 0 193 193 1 1
    ATF6 SEC16A 0 0 161 201 1 2
    ATF6 TCL1B 0 0 414 414 1 1
    ATF6 GOLPH3 0 0 865 865 1 1
    ATF6 NUPR1 0 0 171 171 1 1
    ATF6 GPR78 0 0 517 526 1 1
    ATF6 PRSS57 0 0 143 174 1 1
    ATF6 KDELR1 0 0 258 279 1 1
    ATF6 C9orf72 0 0 182 181 1 2
    ATF6 MYCN 0 0 82 157 1 1
    ATF6 RP1L1 0 0 45 170 1 1
    ATF6 PDZRN4 0 0 0 206 1 1
    ATF6 SOAT1 0 0 74 239 1 1
    ATF6 ACACA 0 0 282 309 1 1
    ATF6 SERPINA5 0 0 85 177 1 1
    ATF6 CERS1 0 0 141 161 1 1
    ATF6 GNAT2 0 0 379 469 1 1
    ATF6 RARG 0 0 0 198 1 1
    ATF6 GFRAL 0 0 75 158 1 1
    ATF6 VAPA 0 0 86 309 1 1
    ATF6 TMBIM6 0 0 425 467 1 1
    ATF6 P4HB 0 0 732 776 1 2
    ATF6 GPX7 0 0 90 185 1 1
    ATF6 GLS 0 0 57 202 1 1
    ATF6 TRAF2 0 0 458 567 1 1
    ATF6 RICTOR 0 0 178 197 1 2
    ATF6 G6PC 0 0 242 241 1 1
    ATF6 BLOC1S1 0 0 195 213 1 1
    ATF6 PCK1 0 0 182 233 1 1
    ATF6 PPARGC1A 0 0 548 637 1 1
    ATF6 SDHC 0 0 319 319 1 1
    ATF6 IGF1R 0 0 150 196 1 1
    ATF6 NR2C1 0 0 0 157 1 1
    ATF6 STEAP3 0 0 61 222 1 1
    ATF6 PDE6H 0 0 395 421 1 1
    ATF6 IL18 0 0 206 206 1 1
    ATF6 CBX5 0 0 51 150 1 1
    ATF6 IFNA1 0 0 181 181 1 1
    ATF6 PARK2 0 0 262 262 1 1
    ATF6 NR0B2 0 0 158 182 1 1
    ATF6 ASNA1 0 0 57 216 1 1
    ATF6 NCSTN 0 0 264 264 1 1
    ATF6 MYC 0 0 328 328 1 2
    ATF6 FOXN3 0 0 0 422 1 1
    ATF6 IRGM 0 0 253 252 1 2
    ATF6 HIPK1 0 0 0 160 1 1
    ATF6 WFS1 270 800 416 924 1 1
    ATF6 DGAT1 0 0 170 185 1 1
    ATF6 MAP2K7 0 0 240 239 1 1
    ATF6 NOS2 0 0 123 155 1 1
    ATF6 GABARAPL2 0 0 282 282 1 2
    ATF6 RD3 0 0 181 181 1 1
    ATF6 SMG1 0 0 126 199 1 1
    ATF6 TENM4 0 0 72 166 1 1
    ATF6 GAPDH 0 0 595 597 1 2
    ATF6 EGR3 0 0 46 205 1 1
    ATF6 ATG14 0 0 257 270 1 2
    ATF6 TMBIM4 0 0 125 350 1 1
    ATF6 TLR4 0 0 325 337 1 1
    ATF6 SMAD2 0 0 170 169 1 1
    ATF6 GPBP1 0 0 66 266 1 1
    ATF6 BCL2L1 0 0 469 482 1 2
    ATF6 RELA 0 0 219 219 1 1
    ATF6 MAPK8IP1 0 0 0 190 1 1
    ATF6 PCDH20 131 0 0 150 1 1
    ATF6 NFKB1 0 0 150 199 1 1
    ATF6 UHRF1 0 0 67 165 1 1
    ATF6 CASP6 0 0 181 186 1 1
    ATF6 DCDC2C 0 0 0 166 1 1
    ATF6 ITPR2 0 0 166 186 1 1
    ATF6 FAM150B 0 0 0 189 1 1
    ATF6 PIK3R4 0 0 181 181 1 2
    ATF6 ATF5 0 0 520 605 1 1
    ATF6 DPAGT1 0 0 181 199 1 1
    ATF6 HSF1 0 0 213 294 1 1
    ATF6 SCAP 0 0 630 630 1 1
    ATF6 SIRT2 0 0 181 181 1 2
    ATF6 HSPD1 0 0 146 196 1 1
    ATF6 CTNND1 0 0 0 477 1 1
    ATF6 PCSK6 0 0 398 398 1 1
    ATF6 FOXM1 0 0 202 232 1 1
    ATF6 RYR3 0 0 328 328 1 1
    ATF6 UNC13C 0 0 0 169 1 1
    ATF6 FGF21 0 0 290 292 1 1
    ATF6 LMAN1 0 0 263 347 1 1
    ATF6 CCNB1 0 0 180 181 1 1
    ATF6 ANXA5 0 0 507 558 1 1
    ATF6 CREB1 130 0 468 552 1 1
    ATF6 CIDEC 0 0 139 157 1 1
    ATF6 SERP1 0 0 280 286 1 1
    ATF6 IL2RB 0 0 0 266 1 1
    ATF6 LMAN2 0 0 107 152 1 1
    ATF6 IFNG 0 0 147 233 1 2
    ATF6 NIT1 0 0 134 168 1 1
    ATF6 BIRC2 0 0 147 164 1 1
    ATF6 ST7 226 0 0 225 1 1
    ATF6 HSPA1L 0 0 70 179 1 1
    ATF6 NFE2 0 0 166 226 1 1
    ATF6 PDXK 0 0 0 190 1 1
    ATF6 SDHB 0 0 183 183 1 1
    ATF6 LONP1 0 0 194 244 1 1
    ATF6 CDNF 0 0 218 684 1 1
    ATF6 ESRRA 0 0 69 223 1 1
    ATF6 ZNF563 0 0 141 154 1 1
    ATF6 PLGRKT 268 0 0 268 1 1
    ATF6 OCLN 0 0 150 173 1 1
    ATF6 SYVN1 270 0 458 723 1 1
    ATF6 NPHS1 0 0 181 181 1 1
    ATF6 PADI1 0 0 120 160 1 1
    ATF6 TNFRSF1A 111 0 215 272 1 1
    ATF6 P4HTM 0 0 112 167 1 1
    ATF6 LGR4 0 0 0 173 1 1
    ATF6 STAT1 0 0 234 234 1 1
    ATF6 ENDOG 0 0 213 227 1 1
    ATF6 IL6 0 0 466 478 1 1
    ATF6 GNA13 0 0 0 194 1 1
    ATF6 GPR37 0 0 150 184 1 1
    ATF6 EPHX2 128 0 75 165 1 1
    ATF6 CTRL 0 0 283 282 1 1
    ATF6 SMN1 0 0 60 271 1 1
    ATF6 PLIN1 0 0 181 181 1 1
    ATF6 PIK3C3 0 0 335 371 1 2
    ATF6 MPO 0 0 139 169 1 1
    ATF6 UCP2 0 0 164 163 1 1
    ATF6 MPZ 0 0 154 153 1 1
    ATF6 POTEF 0 0 139 227 1 1
    ATF6 SEC24D 0 0 287 346 1 1
    ATF6 MAN1B1 0 0 245 244 1 1
    ATF6 MTOR 0 0 466 511 1 2
    ATF6 SEC61A1 0 0 455 464 1 1
    ATF6 NOTCH1 0 0 217 217 1 1
    ATF6 PSEN2 0 0 179 250 1 1
    ATF6 CRELD2 0 0 458 474 1 1
    ATF6 PACS2 0 0 283 282 1 1
    ATF6 DCLK3 0 0 0 163 1 1
    ATF6 PSAT1 0 0 112 173 1 1
    ATF6 RHO 0 0 398 398 1 1
    ATF6 ASRGL1 0 0 0 547 1 1
    ATF6 GANAB 0 0 124 215 1 1
    ATF6 EGR1 0 0 155 173 1 1
    ATF6 MFN2 0 0 325 338 1 2
    ATF6 APP 0 0 320 324 1 1
    ATF6 CDK2 0 0 184 183 1 1
    ATF6 MAP1LC3A 0 0 283 407 1 2
    ATF6 CLSTN3 0 0 0 238 1 1
    ATF6 HRAS 0 0 170 194 1 1
    ATF6 CTNNB1 0 0 242 241 1 1
    ATF6 SEC24B 0 0 183 219 1 1
    ATF6 RQCD1 0 0 0 210 1 1
    ATF6 CXCL8 0 0 321 321 1 1
    ATF6 IL1B 0 0 459 462 1 1
    ATF6 CCT5 0 0 47 156 1 1
    ATF6 NR1H3 0 0 113 187 1 1
    ATF6 EDEM3 0 0 310 383 1 1
    ATF6 SP1 209 0 246 426 1 1
    ATF6 SIRT5 0 0 166 165 1 1
    ATF6 SEC16B 0 0 52 224 1 2
    ATF6 GCK 0 0 181 181 1 1
    ATF6 HIF1A 0 0 360 374 1 2
    ATF6 EDN1 0 0 137 160 1 1
    ATF6 TRPM7 0 0 350 351 1 1
    ATF6 BAG3 0 0 201 218 1 2
    ATF6 MLF2 0 0 54 154 1 1
    ATF6 CEBPA 0 0 496 607 1 1
    ATF6 HTRA2 0 0 210 210 1 1
    ATF6 EPHA7 0 0 0 154 1 1
    ATF6 CRP 0 0 181 191 1 1
    ATF6 ASS1 0 0 48 156 1 1
    ATF6 COX4I1 0 0 202 202 1 1
    ATF6 ELF2 0 0 203 203 1 1
    ATF6 ATF2 0 0 234 278 1 1
    ATF6 PSEN1 0 0 283 325 1 2
    ATF6 UFD1L 0 0 240 245 1 1
    ATF6 TBL2 0 0 156 188 1 1
    ATF6 PNPLA2 0 0 184 226 1 1
    ATF6 HSP90AA1 0 0 485 517 1 2
    ATF6 PDIA2 0 0 283 470 1 1
    ATF6 CREB3L1 0 0 520 593 1 1
    ATF6 TFEB 0 0 206 217 1 2
    ATF6 SIRT3 0 0 194 194 1 2
    ATF6 ROS1 0 0 0 301 1 1
    ATF6 GTF2I 270 0 709 778 1 1
    ATF6 MAPK3 0 0 298 354 1 2
    ATF6 MMP9 0 0 218 218 1 1
    ATF6 B2M 0 0 307 307 1 1
    ATF6 HSPE1 0 0 170 169 1 1
    ATF6 GAL3ST1 0 0 0 235 1 1
    ATF6 KEAP1 0 0 370 413 1 2
    ATF6 BNIP3 0 0 267 267 1 2
    ATF6 SQSTM1 0 0 423 427 1 2
    ATF6 DCDC2B 0 0 0 166 1 1
    ATF6 RNF5 0 0 230 243 1 1
    ATF6 TRAM1 0 0 145 239 1 1
    ATF6 JUNB 0 0 102 254 1 1
    ATF6 VWA5A 0 0 45 214 1 1
    ATF6 ACTB 0 0 609 649 1 1
    ATF6 FAM150A 0 0 45 163 1 1
    ATF6 ATG13 0 0 290 306 1 2
    ATF6 RAD21L1 0 0 0 570 1 1
    ATF6 INS 0 0 604 616 1 1
    ATF6 GLP1R 0 0 165 184 1 1
    ATF6 DNMT1 0 0 100 161 1 1
    ATF6 STUB1 0 0 234 234 1 2
    ATF6 EDEM2 0 0 325 454 1 1
    ATF6 EPRS 0 0 66 217 1 1
    ATF6 MED25 0 0 447 447 1 1
    ATF6 TARDBP 0 0 176 194 1 1
    ATF6 EIF5 0 0 122 191 1 1
    ATF6 STX1A 0 0 184 220 1 1
    ATF6 RCAN2 0 0 398 398 1 1
    ATF6 GNA12 0 0 0 206 1 1
    ATF6 MTTP 0 0 124 178 1 1
    ATF6 BAX 0 0 379 379 1 2
    ATF6 ATG9A 0 0 142 336 1 2
    ATF6 ERP44 0 0 370 395 1 1
    ATF6 SPP1 0 0 134 157 1 1
    ATF6 NKRF 0 0 201 213 1 1
    ATF6 CDKN1A 0 0 194 194 1 2
    ATF6 AR 0 0 159 234 1 1
    ATF6 KCNH2 0 0 113 265 1 1
    ATF6 PARP1 0 0 265 467 1 2
    ATF6 EIF4G1 0 0 155 217 1 2
    ATF6 CRTC2 270 0 274 785 1 1
    ATF6 HSPA8 0 0 368 432 1 2
    ATF6 BID 0 0 201 205 1 1
    ATF6 GSR 0 0 202 202 1 1
    ATF6 SAR1A 270 0 125 369 1 1
    ATF6 ENSG00000269590 0 0 0 256 1 1
    ATF6 GIGYF2 0 0 0 167 1 1
    ATF6 GABARAPL1 0 0 288 288 1 2
    ATF6 ICAM1 0 0 206 207 1 1
    ATF6 SEC31A 0 0 143 214 1 1
    ATF6 IGFBP2 0 0 270 270 1 1
    ATF6 MLKL 0 0 164 184 1 1
    ATF6 SMDT1 0 0 0 189 1 1
    ATF6 TOR1AIP2 0 0 0 209 1 1
    ATF6 COMP 0 0 150 284 1 1
    ATF6 ERN2 0 0 634 717 1 1
    ATF6 ARNT 0 0 146 211 1 2
    ATF6 DNAJC3 0 0 681 742 1 1
    ATF6 CDC25C 0 0 72 197 1 1
    ATF6 LTA 0 0 43 222 1 1
    ATF6 SOD1 0 0 370 385 1 1
    ATF6 VCP 0 0 388 403 1 2
    ATF6 CAPN2 0 0 207 222 1 2
    ATF6 CREB3L2 0 0 529 330 1 1
    ATF6 NARF 0 0 0 223 1 1
    ATF6 LAMP2 0 0 244 273 1 2
    ATF6 ZBED4 0 0 0 154 1 1
    ATF6 FDPS 0 0 52 199 1 1
    ATF6 GOLGA2 0 0 230 229 1 1
    ATF6 SEL1L2 0 0 0 205 1 1
    ATF6 CREB3 0 0 519 567 1 1
    ATF6 CNPY3 0 0 52 154 1 1
    ATF6 CHST12 0 0 0 477 1 1
    ATF6 NOS1AP 0 0 164 286 1 1
    ATF6 YY2 0 0 60 157 1 1
    ATF6 TFAM 0 0 559 559 1 1
    ATF6 RIPK2 0 0 113 157 1 1
    ATF6 TRIM3 0 0 325 340 1 1
    ATF6 IRS2 0 0 235 236 1 1
    ATF6 CD8A 0 0 209 209 1 1
    ATF6 APBB1 0 0 72 216 1 1
    ATF6 ERLEC1 393 0 246 522 1 1
    ATF6 CALR 0 900 876 990 1 1
    ATF6 BIK 0 0 342 342 1 1
    ATF6 MFN1 0 0 208 208 1 1
    ATF6 EIF4E3 0 0 0 224 1 1
    ATF6 EIF2AK2 0 0 504 765 1 2
    ATF6 ULK2 0 0 184 183 1 2
    ATF6 SELK 0 0 120 180 1 1
    ATF6 MAP2K3 0 0 161 161 1 1
    ATF6 TNFSF10 0 0 150 203 1 2
    ATF6 CAV1 0 0 140 230 1 1
    ATF6 CHRNA7 0 0 0 369 1 1
    ATF6 SRF 270 0 786 848 1 1
    ATF6 SIK2 0 0 397 396 1 1
    ATF6 ORMDL3 0 0 290 331 1 1
    ATF6 CERS5 0 0 162 161 1 1
    ATF6 HSPA1A 0 0 324 403 1 1
    ATF6 DEDD 0 0 49 196 1 1
    ATF6 CASP1 0 0 335 396 1 2
    ATF6 UBXN4 0 0 161 201 1 1
    ATF6 EIF2AK1 0 0 344 413 1 1
    ATF6 INA 0 0 166 165 1 1
    ATF6 DNTT 0 0 391 404 1 1
    ATF6 CRTC3 0 0 325 420 1 1
    ATF6 SNCA 0 0 341 412 1 2
    ATF6 DAPK1 0 0 282 303 1 2
    ATF6 TNIP3 0 0 45 304 1 1
    ATF6 GOLGB1 0 0 142 196 1 1
    ATF6 MAFB 0 0 92 193 1 1
    ATF6 ITPR3 0 0 460 473 1 1
    ATF6 JUN 0 0 691 791 1 1
    ATF6 BATF 0 0 156 342 1 1
    ATF6 TAPBP 0 0 108 198 1 1
    ATF6 MAN2A1 0 0 75 337 1 1
    ATF6 CNGA1 0 0 0 190 1 1
    ATF6 NRF1 0 0 134 170 1 1
    ATF6 AMFR 0 0 435 470 1 1
    ATF6 MTHFD2 0 0 149 202 1 1
    ATF6 SERPINA1 0 0 275 351 1 2
    ATF6 WDR5 0 0 50 213 1 1
    ATF6 BCL2L11 0 0 563 593 1 1
    ATF6 FBXO4 0 0 74 266 1 1
    ATF6 RPAP2 0 0 112 155 1 1
    ATF6 PPARA 0 0 337 433 1 1
    ATF6 NFYA 192 0 389 485 1 1
    ATF6 RDH5 0 0 89 151 1 1
    ATF6 LPL 0 0 134 166 1 1
    ATF6 MIEF1 0 0 61 382 1 1
    ATF6 HSP90B1 0 900 786 985 1 1
    ATF6 CYP2E1 0 0 260 272 1 1
    ATF6 RPTOR 0 0 247 306 1 2
    ATF6 HSPB3 0 0 323 323 1 1
    ATF6 DDX1 0 0 74 226 1 1
    ATF6 DICER1 0 0 113 174 1 1
    ATF6 PPIB 0 0 204 204 1 1
    ATF6 PIK3R1 0 0 143 175 1 1
    ATF6 SEC23A 0 0 95 187 1 2
    ATF6 HSPA4 0 0 560 585 1 1
    ATF6 SMARCA2 0 0 0 207 1 1
    ATF6 ETS1 0 0 124 182 1 1
    ATF6 PCSK1 0 0 135 222 1 1
    ATF6 FASN 0 0 293 318 1 1
    ATF6 HNF1A 0 0 193 193 1 1
    ATF6 AKR1B1 0 0 123 152 1 1
    ATF6 SP4 0 0 261 272 1 1
    ATF6 EGF 0 0 244 261 1 1
    ATF6 BMP2 0 0 184 203 1 1
    ATF6 WBP1 0 0 216 224 1 1
    ATF6 RPS6KA3 0 0 107 168 1 1
    ATF6 DUSP12 0 0 126 519 1 1
    ATF6 MAN2B2 0 0 0 342 1 1
    ATF6 CYCS 0 0 566 575 1 1
    ATF6 MAPK9 0 0 303 326 1 2
    ATF6 ITPR1 0 0 466 479 1 2
    ATF6 CASP9 0 0 562 604 1 1
    ATF6 GULP1 0 0 54 200 1 1
    ATF6 TRAF6 0 0 172 219 1 2
    ATF6 PLD1 0 0 306 306 1 1
    ATF6 MAP2K4 0 0 177 177 1 1
    ATF6 SREK1IP1 0 0 0 240 1 1
    ATF6 SPCS2 0 0 141 481 1 1
    ATF6 MAPK8 0 0 519 533 1 2
    ATF6 ARG1 0 0 89 151 1 1
    ATF6 GCLC 0 0 244 260 1 1
    ATF6 SRP19 0 0 46 426 1 1
    ATF6 EIF2S2 0 0 207 217 1 1
    ATF6 ADIPOQ 0 0 260 260 1 1
    ATF6 PDRG1 0 0 47 292 1 1
    ATF6 CENPF 0 0 433 433 1 1
    ATF6 PKP2 0 0 0 241 1 1
    ATF6 MBTPS2 0 900 705 976 1 1
    ATF6 VPS52 0 0 66 659 1 1
    ATF6 PRNP 0 0 159 190 1 1
    ATF6 CTGF 0 0 150 188 1 1
    ATF6 GRINA 0 0 150 319 1 1
    ATF6 TRAPPC11 0 0 67 420 1 1
    ATF6 SESN2 0 0 267 267 1 2
    ATF6 NFIC 0 0 46 217 1 1
    ATF6 HSPA6 0 0 123 212 1 1
    ATF6 DIABLO 0 0 232 231 1 1
    ATF6 HIST2H3PS2 0 0 216 216 1 1
    ATF6 GPX4 0 0 120 158 1 1
    ATF6 TRADD 0 0 161 166 1 1
    ATF6 PAX6 0 0 54 170 1 1
    ATF6 IAPP 0 0 182 196 1 1
    ATF6 ALK 0 0 45 181 1 1
    ATF6 ATP2A1 0 0 164 264 1 1
    ATF6 CRYGC 0 0 155 154 1 1
    ATF6 MAVS 0 0 142 161 1 1
    ATF6 AQP2 0 0 92 182 1 1
    ATF6 NFIL3 0 0 81 223 1 1
    ATF6 LGALS4 0 0 215 233 1 1
    ATF6 MAF 0 0 210 298 1 1
    ATF6 FSD1 0 0 0 198 1 1
    ATF6 SPCS1 0 0 82 445 1 1
    ATF6 CDH1 0 0 150 189 1 1
    ATF6 MLXIPL 0 0 229 228 1 1
    ATF6 SGK494 0 0 0 175 1 1
    ATF6 DDX58 0 0 210 210 1 1
    ATF6 HMGCS2 0 0 56 205 1 1
    ATF6 HLF 0 0 45 192 1 1
    ATF6 MAPKAPK2 0 0 123 158 1 1
    ATF6 EPHA4 0 0 0 154 1 1
    ATF6 CERS2 0 0 206 206 1 1
    ATF6 ATP13A4 0 0 0 241 1 1
    ATF6 HYOU1 0 0 520 584 1 1
    ATF6 DRAM2 0 0 74 284 1 2
    ATF6 REC8 0 0 0 414 1 1
    ATF6 ERO1L 0 0 636 668 1 1
    ATF6 TNFRSF10A 0 0 228 272 1 1
    ATF6 ANXA8 0 0 230 229 1 1
    ATF6 SEC63 0 0 324 508 1 1
    ATF6 SPARC 128 0 90 172 1 1
    ATF6 SMAD3 0 0 154 153 1 1
    ATF6 SEC23B 0 0 136 224 1 2
    ATF6 OLFML2B 0 0 143 298 1 1
    ATF6 AUP1 0 0 430 430 1 1
    ATF6 CSNK2A2 0 0 0 157 1 1
    ATF6 HCFC1 0 0 95 172 1 1
    ATF6 CALU 0 0 107 162 1 1
    ATF6 IL4 0 0 150 173 1 1
    ATF6 CDK5 0 0 151 150 1 2
    ATF6 EP300 0 0 167 167 1 1
    ATF6 TCF19 0 0 0 317 1 1
    ATF6 SRP72 0 0 75 458 1 1
    ATF6 SELM 0 0 122 176 1 1
    ATF6 SNAPC3 0 0 0 525 1 1
    ATF6 THBS4 0 0 707 906 1 1
    ATF6 HERPUD1 0 0 560 626 1 1
    ATF6 CASP7 0 0 455 476 1 1
    ATF6 AOAH 0 0 0 455 1 1
    ATF6 RCAN3 0 0 397 396 1 1
    ATF6 DCLK1 0 0 0 241 1 1
    ATF6 CASP8 0 0 502 521 1 2
    ATF6 CD68 0 0 181 181 1 1
    ATF6 ALB 0 0 459 517 1 1
    ATF6 CCL2 0 0 321 321 1 2
    ATF6 GYPC 0 0 117 212 1 1
    ATF6 RPL19 0 0 150 197 1 1
    ATF6 BAG2 0 0 125 179 1 1
    ATF6 CREB3L3 270 0 928 568 1 1
    ATF6 EIF4A1 0 0 123 183 1 1
    ATF6 LEPR 0 0 166 173 1 1
    Ontologies
    ID Category Term Effect Evidence PubMed
    GO:0001228 Molecular Function DNA-binding transcription activator activity, RNA polymerase II-specific enables IDA
    GO:0003700 Molecular Function DNA-binding transcription factor activity enables IDA
    GO:0000981 Molecular Function DNA-binding transcription factor activity, RNA polymerase II-specific enables IBA
    GO:0000981 Molecular Function DNA-binding transcription factor activity, RNA polymerase II-specific enables ISA
    GO:0000978 Molecular Function RNA polymerase II cis-regulatory region sequence-specific DNA binding enables IBA
    GO:0000978 Molecular Function RNA polymerase II cis-regulatory region sequence-specific DNA binding enables IDA
    GO:0000977 Molecular Function RNA polymerase II transcription regulatory region sequence-specific DNA binding enables IDA
    GO:0019899 Molecular Function enzyme binding enables IPI
    GO:0042802 Molecular Function identical protein binding enables IPI
    GO:0005515 Molecular Function protein binding enables IPI
    GO:0046982 Molecular Function protein heterodimerization activity enables IPI
    GO:0043565 Molecular Function sequence-specific DNA binding enables IDA
    GO:1990837 Molecular Function sequence-specific double-stranded DNA binding enables IDA
    GO:0000976 Molecular Function transcription cis-regulatory region binding enables IDA
    GO:0036500 Biological Process ATF6-mediated unfolded protein response involved_in NAS
    GO:0036500 Biological Process ATF6-mediated unfolded protein response involved_in TAS
    GO:0036503 Biological Process ERAD pathway involved_in NAS
    GO:0030968 Biological Process endoplasmic reticulum unfolded protein response involved_in IBA
    GO:0030968 Biological Process endoplasmic reticulum unfolded protein response involved_in TAS
    GO:0001654 Biological Process eye development involved_in IMP
    GO:1903893 Biological Process positive regulation of ATF6-mediated unfolded protein response involved_in IDA
    GO:0043065 Biological Process positive regulation of apoptotic process involved_in IDA
    GO:0010508 Biological Process positive regulation of autophagy acts_upstream_of_or_within IMP
    GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II involved_in IDA
    GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II involved_in TAS
    GO:0006457 Biological Process protein folding involved_in TAS
    GO:0006357 Biological Process regulation of transcription by RNA polymerase II involved_in IBA
    GO:0006357 Biological Process regulation of transcription by RNA polymerase II involved_in NAS
    GO:0034976 Biological Process response to endoplasmic reticulum stress involved_in IDA
    GO:0034976 Biological Process response to endoplasmic reticulum stress involved_in TAS
    GO:0007165 Biological Process signal transduction involved_in TAS
    GO:0007601 Biological Process visual perception involved_in IMP
    GO:0005794 Cellular Component Golgi apparatus located_in IDA
    GO:0000139 Cellular Component Golgi membrane located_in TAS
    GO:0090575 Cellular Component RNA polymerase II transcription regulator complex part_of IPI
    GO:0000785 Cellular Component chromatin located_in ISA
    GO:0005829 Cellular Component cytosol located_in TAS
    GO:0005783 Cellular Component endoplasmic reticulum located_in IDA
    GO:0005789 Cellular Component endoplasmic reticulum membrane located_in IDA
    GO:0005789 Cellular Component endoplasmic reticulum membrane located_in NAS
    GO:0005789 Cellular Component endoplasmic reticulum membrane located_in TAS
    GO:0016020 Cellular Component membrane located_in IDA
    GO:0005635 Cellular Component nuclear envelope located_in TAS
    GO:0005654 Cellular Component nucleoplasm located_in TAS
    GO:0005634 Cellular Component nucleus is_active_in IBA
    GO:0005634 Cellular Component nucleus located_in IDA
    GO:0005634 Cellular Component nucleus located_in NAS
    GO:0005634 Cellular Component nucleus located_in TAS
    Pathways
    Name DB ID
    Cellular responses to stress Reactome R-HSA-2262752
    ATF4 activates genes in response to endoplasmic reticulum stress Reactome R-HSA-380994
    ATF6 (ATF6-alpha) activates chaperones Reactome R-HSA-381033
    PERK regulates gene expression Reactome R-HSA-381042
    Unfolded Protein Response (UPR) Reactome R-HSA-381119
    ATF6 (ATF6-alpha) activates chaperone genes Reactome R-HSA-381183
    Cellular responses to stimuli Reactome R-HSA-8953897
    Alzheimer's disease (WP5124) WikiPathways WP5124_r123917
    Endoplasmic reticulum stress response in coronavirus infection (WP4861) WikiPathways WP4861_r124658
    Sterol regulatory element-binding proteins (SREBP) signaling (WP1982) WikiPathways WP1982_r116442
    Alzheimer's disease and miRNA effects (WP2059) WikiPathways WP2059_r119468
    Unfolded protein response (WP4925) WikiPathways WP4925_r123438
    Photodynamic therapy-induced unfolded protein response (WP3613) WikiPathways WP3613_r106539
    VEGFA-VEGFR2 signaling pathway (WP3888) WikiPathways WP3888_r116782
    Transcripts
    Accession Version MolecularType Name NCBI Comments
    XM_011509308 1 mRNA transcript variant X1 NC_000001 Reference
    XM_011509309 1 mRNA transcript variant X2 NC_000001 Reference
    NM_007348 4 mRNA transcript variant 1 NC_000001 Reference
    NM_001410890 1 mRNA transcript variant 2 NC_000001 Reference
    XM_047449542 1 mRNA transcript variant X4 NC_000001 Reference
    XM_011509310 3 mRNA transcript variant X3 NC_000001 Reference