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PHLPP1

PH domain and leucine rich repeat protein phosphatase 1
General Information
Name PH domain and leucine rich repeat protein phosphatase 1
Alias
  • PH domain leucine-rich repeat-containing protein phosphatase 1
  • PH domain-containing family E member 1
  • SCN circadian oscillatory protein
  • pleckstrin homology domain containing, family E (with leucine rich repeats) member 1
  • protein phosphatase, Mg2+/Mn2+ dependent 3A
  • suprachiasmatic nucleus circadian oscillatory protein
Gene_family Pleckstrin homology domain containing|Protein phosphatases, Mg2+/Mn2+ dependent
organism Homo sapiens
entrez_id 23239
location 18q21.33
transcript_count 1
exon_count 17
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling. [provided by RefSeq, Dec 2011]
    Stringdb PH domain leucine-rich repeat-containing protein phosphatase 1; Protein phosphatase involved in regulation of Akt and PKC signaling. Mediates dephosphorylation in the C-terminal domain hydrophobic motif of members of the AGC Ser/Thr protein kinase family; specifically acts on 'Ser-473' of AKT2 and AKT3, 'Ser-660' of PRKCB and 'Ser-657' of PRKCA. Isoform 2 seems to have a major role in regulating Akt signaling in hippocampal neurons (By similarity). Akt regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors [...]
    nextProt Seems to have a major role in regulating Akt signaling in hippocampal neurons (By similarity). Akt regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of 'Ser-473' of Akt triggers apoptosis and suppression of tumor growth. Dephosphorylation of PRKCA and PRKCB leads to their destabilization and degradation (PubMed:18162466). Dephosphorylates STK4 on 'Thr-387' leading to STK4 activation and apoptosis (PubMed:20513427). Dephosphorylates RPS6KB1 and is involved in regulation of cap-dependent translation (PubMed:21986499). Inhibits cancer cell proliferation and may act as a tumor suppressor (PubMed:19079341). Dephosphorylates RAF1 inhibiting its kinase activity (PubMed:24530606). May act as a negative regulator of K-Ras signaling in membrane rafts (By similarity). Involved in the hippocampus-dependent long-term memory formation (By similarity). Involved in circadian control by regulating the consolidation of circadian periodicity after resetting (By similarity). Involved in development and function of regulatory T-cells (By similarity).
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
PHLPP1 BioGRID TRIM11 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
PHLPP1 BioGRID TRIM67 GeneID BioGRID Affinity Capture-MS
PHLPP1 BioGRID GOLGA8O GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID ASPM GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID CBARP GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID JMJD1C GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID FAM91A1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID CDCA2 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID MPP7 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID MISP GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID AHNAK2 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID WDR20 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Proximity Label-MS
PHLPP1 BioGRID TANC1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID TNKS1BP1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID MYPN GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID EPPK1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID VANGL1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID DIAPH3 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID SNX27 GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
PHLPP1 BioGRID VCPIP1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID RPAP3 GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
PHLPP1 BioGRID MAP7D3 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID EFHD2 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID CSTPP1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID AHNAK GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID KRI1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID RAPH1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID NUCKS1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID RBM26 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID STEEP1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID SH2D4A GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID EPS15L1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID SUGP1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID SHTN1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID ZDBF2 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID CIP2A GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID WDR48 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Proximity Label-MS; Reconstituted Complex
PHLPP1 BioGRID NUFIP2 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID KIDINS220 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID CORO1B GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID RTN4 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID PCNP GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID KNL1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID KIF15 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID ZC3HAV1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID MUC13 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID EIF4ENIF1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID UNC45A GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID ZC3H15 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID UBAP2 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID DEPDC1B GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID ARFGAP1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID CCDC88A GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID DENND4C GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID HEATR1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID ATG2B GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID KIF26B GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID PIH1D1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID SPDL1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID HAUS6 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID PLEKHA5 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID XRN1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID ANLN GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID RBM27 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID RAPGEF6 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID GTSE1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID LIMA1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID CACYBP GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID SND1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID COPG2 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID ELP4 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID MYOF GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID RAI14 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID GIGYF2 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID ANKRD17 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID KANK2 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID GEMIN5 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID ZNF318 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID IFIT5 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID CD2AP GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID CORO1C GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID SCRIB GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
PHLPP1 BioGRID SF3B1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID COTL1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID NCAPH GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID LARP1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID ESYT1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID SYNM GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID SIN3B GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID PRRC2C GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID EFR3A GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID SWAP70 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID SNRNP200 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID LIMCH1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID TPX2 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID SNW1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID PDAP1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID STK38 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID DDX42 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID ECD GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID ATXN2L GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID CDC37 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID DIDO1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID CPSF6 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID SF3B2 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID GCN1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID FERMT2 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID SUGT1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Proximity Label-MS
PHLPP1 BioGRID HSPH1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID NES GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID NUDC GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID CCT8 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID SPAG5 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID PRPF8 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID CCT4 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID IPO7 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID MYBBP1A GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID BASP1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID TUBB4B GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID KIF20A GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID ABCF2 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID SMC4 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID ZBTB33 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID USP15 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID SEC16A GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID UBAP2L GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID CEP170 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID CKAP5 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID DLGAP5 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID SLK GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID CLINT1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID EIF5B GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID SLC4A7 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID KIF23 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID TXNL1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID PDLIM7 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID DLG5 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID USP10 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID MAP7 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID AP3D1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID SQSTM1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID RUVBL1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID RANBP3 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID TAGLN2 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID RBM10 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID SLC7A5 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID NUP214 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID TUBA1A GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID CSDE1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID LUZP1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID SLC30A1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID SF1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID WARS1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID USP1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Proximity Label-MS; Reconstituted Complex
PHLPP1 BioGRID SUMO1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID TUBA4A GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID TPR GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID TLN1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID TJP1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID TFRC GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID TCOF1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID STAT3 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID SRP68 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID SPTAN1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID SNX1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID SNRPA1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID SLC3A2 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID SLC1A5 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID S100A6 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID RRBP1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID RPS27 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID RPS26 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID RPS11 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID RPS6 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID RPL24 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID RPL3 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID ROBO1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID RARS1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID RANGAP1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID RANBP2 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID PRKDC GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID POLR2A GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID POLH GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID PLK1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID PLEC GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID PLA2G4A GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID PKM GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID PFN1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID PCM1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID PA2G4 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID OLR1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID NUP98 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID NASP GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID NAP1L4 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID NAP1L1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID NACA GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID MYH9 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID MSN GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID MRE11 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID MFAP1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID CLTC GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID CHD3 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID CENPF GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID CDK6 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID BUB1B GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID ATP1A1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID APC GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID ACLY GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID ABCF1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID MCAM GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID MAP4 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID NBR1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID LMO7 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID LDHA GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID KRT18 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID KRT8 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID KRT7 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID KIFC1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID KIF11 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID KIF5B GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID JUP GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID HSPA8 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID HSPA1A GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID HDLBP GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID HCFC1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID GTF2I GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID GOLGB1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID GOLGA2 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID FLNB GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID FLNA GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID FASN GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID EPRS1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID EPB41L2 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID EPB41 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID CTTN GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID EIF5 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID EIF4G2 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID EIF4G1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID EIF4B GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID EPHA2 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID EIF2S3 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID EIF2S1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID EGFR GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID EEF1D GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID DVL3 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID DVL2 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID DVL1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID DSP GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID DSG2 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID DYNC1H1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID DLG1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID DDX3X GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID CTPS1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID CTNND1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID CRK GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID COPB1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID CNN2 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID FBXO22 GeneID BioGRID Affinity Capture-Western
PHLPP1 BioGRID PMEPA1 GeneID BioGRID Affinity Capture-Western
PHLPP1 BioGRID NEDD4 GeneID BioGRID Affinity Capture-Western
PHLPP1 BioGRID RFPL2 GeneID BioGRID Affinity Capture-MS
PHLPP1 BioGRID NHERF2 GeneID BioGRID Affinity Capture-MS
PHLPP1 BioGRID PRPS2 GeneID BioGRID Affinity Capture-MS
PHLPP1 BioGRID EFNB2 GeneID BioGRID Affinity Capture-MS
PHLPP1 BioGRID EFNB1 GeneID BioGRID Affinity Capture-MS
PHLPP1 BioGRID HAVCR2 GeneID BioGRID Affinity Capture-MS
PHLPP1 BioGRID USP46 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Proximity Label-MS; Reconstituted Complex
PHLPP1 BioGRID KRAS GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID LDLR GeneID BioGRID Positive Genetic
PHLPP1 BioGRID ITGB1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID FKBP5 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
PHLPP1 BioGRID VIRMA GeneID BioGRID Affinity Capture-RNA
PHLPP1 BioGRID TBC1D7 GeneID BioGRID Affinity Capture-Western
PHLPP1 BioGRID IRS4 GeneID BioGRID Affinity Capture-MS
PHLPP1 BioGRID USP12 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Proximity Label-MS
PHLPP1 BioGRID COA1 GeneID BioGRID Affinity Capture-MS
PHLPP1 BioGRID STUB1 GeneID BioGRID Affinity Capture-MS
PHLPP1 BioGRID AKT1 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
PHLPP1 BioGRID FANCI GeneID BioGRID Affinity Capture-Western
PHLPP1 BioGRID TRIM25 GeneID BioGRID Affinity Capture-RNA
PHLPP1 BioGRID SKP2 GeneID BioGRID Affinity Capture-MS
PHLPP1 BioGRID PPP2R2A GeneID BioGRID Affinity Capture-MS
PHLPP1 BioGRID PPP2R1A GeneID BioGRID Affinity Capture-MS
PHLPP1 BioGRID FKBP4 GeneID BioGRID Affinity Capture-MS
PHLPP1 BioGRID MCMBP GeneID BioGRID Affinity Capture-MS
PHLPP1 BioGRID RBM15 GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
PHLPP1 BioGRID NUDCD3 GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
PHLPP1 BioGRID AGTPBP1 GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID PHLPP2 GeneID BioGRID Affinity Capture-MS
PHLPP1 BioGRID GLMN GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID BAG2 GeneID BioGRID Affinity Capture-MS
PHLPP1 BioGRID NHERF1 GeneID BioGRID Affinity Capture-Western; Far Western; Reconstituted Complex
PHLPP1 BioGRID AIP GeneID BioGRID Proximity Label-MS
PHLPP1 BioGRID BRAP GeneID BioGRID Reconstituted Complex; Two-hybrid
PHLPP1 BioGRID Ppp2r3a GeneID BioGRID Affinity Capture-MS
PHLPP1 BioGRID Taf15 GeneID BioGRID Affinity Capture-MS
PHLPP1 BioGRID Max GeneID BioGRID Affinity Capture-MS
PHLPP1 BioGRID Bub1 GeneID BioGRID Affinity Capture-MS
PHLPP1 BioGRID MAPK8 GeneID BioGRID Affinity Capture-MS
PHLPP1 BioGRID HDAC1 GeneID BioGRID Affinity Capture-MS
PHLPP1 BioGRID BTRC GeneID BioGRID Affinity Capture-Western
PHLPP1 BioGRID BUD23 GeneID BioGRID Co-fractionation
PHLPP1 BioGRID SNX6 GeneID BioGRID Co-fractionation
PHLPP1 BioGRID ELAVL1 GeneID BioGRID Affinity Capture-RNA
PHLPP1 BioGRID PPP5C GeneID BioGRID Affinity Capture-MS
PHLPP1 BioGRID MARK2 GeneID BioGRID Affinity Capture-MS
PHLPP1 BioGRID DMWD GeneID BioGRID Affinity Capture-MS
PHLPP1 BioGRID GSK3B GeneID BioGRID Biochemical Activity
PHLPP1 BioGRID CSNK1A1 GeneID BioGRID Biochemical Activity
PHLPP1 Protein AKT1 GeneID BIND PHLPP interacts with Akt. This interaction was modelled on a demonstrated interaction between human PHLPP and Akt from an unspecified species.
StringDB
A B experiments database textmining combined score hadb nhadb
PHLPP1 PRKAR2B 0 0 0 555 1 1
PHLPP1 PRKAG1 0 0 0 240 1 1
PHLPP1 BAAT 0 0 113 166 1 1
PHLPP1 ARL1 0 0 0 169 1 1
PHLPP1 ERBB2IP 0 0 136 157 1 1
PHLPP1 ACTRT3 0 0 0 254 1 1
PHLPP1 EPHA2 0 0 64 195 1 1
PHLPP1 CDK2 0 0 146 254 1 2
PHLPP1 PDE7A 0 0 0 333 1 1
PHLPP1 DOCK1 0 0 0 205 1 1
PHLPP1 KIAA1429 270 0 0 270 1 1
PHLPP1 MAPK13 0 0 0 333 1 1
PHLPP1 CCT5 0 0 0 329 1 1
PHLPP1 KREMEN2 0 0 0 158 1 1
PHLPP1 PRKCB 282 0 150 372 1 2
PHLPP1 HIF1A 0 0 235 282 1 2
PHLPP1 ARHGEF4 0 0 0 277 1 1
PHLPP1 RPS6 0 0 284 284 1 2
PHLPP1 ACTR2 0 0 0 179 1 1
PHLPP1 BTBD10 0 0 122 272 1 1
PHLPP1 RAB12 0 0 0 268 1 2
PHLPP1 PRKG1 0 0 0 283 1 1
PHLPP1 DDX21 0 0 73 170 1 1
PHLPP1 POTEF 0 0 0 460 1 1
PHLPP1 MTMR3 0 0 45 150 1 2
PHLPP1 CALM1 0 0 0 230 1 1
PHLPP1 RHOU 0 0 0 169 1 1
PHLPP1 ATF7-NPFF 0 0 0 168 1 1
PHLPP1 PTPN13 0 0 60 192 1 1
PHLPP1 NOTCH1 0 0 143 150 1 2
PHLPP1 MYL5 0 0 0 278 1 1
PHLPP1 MAST1 0 0 0 267 1 1
PHLPP1 KREMEN1 0 0 0 158 1 1
PHLPP1 TNFSF18 0 0 44 189 1 1
PHLPP1 TANC1 0 0 0 153 1 1
PHLPP1 PPP2R2A 129 0 216 297 1 1
PHLPP1 ENSG00000258472 0 0 0 167 1 1
PHLPP1 PDP2 0 0 203 344 1 1
PHLPP1 ANXA5 0 0 161 161 1 2
PHLPP1 PDE11A 0 0 0 333 1 1
PHLPP1 PDE4C 0 0 0 364 1 1
PHLPP1 ARF1 0 0 0 169 1 1
PHLPP1 JHDM3C 0 0 46 180 1 1
PHLPP1 ARL3 0 0 0 208 1 1
PHLPP1 MPPE1 0 0 0 201 1 1
PHLPP1 MAPK4 0 0 0 277 1 1
PHLPP1 GRB10 0 0 142 164 1 1
PHLPP1 PRKACA 0 0 0 456 1 1
PHLPP1 NF1 0 0 134 546 1 1
PHLPP1 POTEE 0 0 0 460 1 1
PHLPP1 RAP1A 0 0 0 268 1 1
PHLPP1 RIT2 0 0 0 287 1 1
PHLPP1 BCL2L1 0 0 134 176 1 2
PHLPP1 TUBB4A 0 0 145 170 1 1
PHLPP1 TEC 0 0 0 160 1 1
PHLPP1 LONRF2 0 0 0 178 1 1
PHLPP1 ZNF500 0 0 132 253 1 1
PHLPP1 GNAT2 0 0 0 519 1 1
PHLPP1 PIK3CA 0 0 391 436 1 2
PHLPP1 FBP2 0 0 0 308 1 1
PHLPP1 PPP3CB 0 0 0 219 1 1
PHLPP1 GNAT3 0 0 0 519 1 1
PHLPP1 RIT1 0 0 0 268 1 1
PHLPP1 IGF1R 0 0 246 280 1 2
PHLPP1 SDHC 0 0 151 159 1 1
PHLPP1 STK32B 0 0 0 209 1 1
PHLPP1 ARL8B 0 0 0 169 1 1
PHLPP1 HIPK1 0 0 0 160 1 1
PHLPP1 PDK1 0 0 43 202 1 2
PHLPP1 MYC 0 0 310 370 1 2
PHLPP1 UBBP4 0 0 0 188 1 1
PHLPP1 MAGI1 0 0 0 162 1 1
PHLPP1 MAP2K1 0 0 170 323 1 1
PHLPP1 PIP4K2A 0 0 74 183 1 1
PHLPP1 RSG1 0 0 0 268 1 1
PHLPP1 PHLDA3 0 0 180 179 1 1
PHLPP1 AKT2 0 900 774 983 1 2
PHLPP1 SEC14L2 0 0 195 213 1 1
PHLPP1 NFE2L2 0 0 137 271 1 2
PHLPP1 MAP2K5 0 0 0 172 1 1
PHLPP1 TAX1BP1 0 0 53 152 1 2
PHLPP1 C1orf194 0 0 175 175 1 1
PHLPP1 SHANK1 0 0 0 151 1 1
PHLPP1 ZBTB39 0 0 156 220 1 1
PHLPP1 HDAC3 0 0 117 155 1 2
PHLPP1 PPP3CC 0 0 70 242 1 1
PHLPP1 MYCN 0 0 113 160 1 1
PHLPP1 SMAD4 0 0 228 306 1 2
PHLPP1 RPRD2 0 0 120 272 1 1
PHLPP1 RASGRP2 0 0 0 191 1 1
PHLPP1 PRKACG 0 0 0 456 1 1
PHLPP1 ARF5 0 0 0 169 1 1
PHLPP1 PRKX 0 0 0 456 1 1
PHLPP1 SLC9A3R2 674 0 74 685 1 1
PHLPP1 ZBTB26 0 0 117 151 1 1
PHLPP1 HK2 0 0 484 531 1 2
PHLPP1 ACTRT1 0 0 0 250 1 1
PHLPP1 TXK 0 0 0 220 1 1
PHLPP1 PRIMA1 0 0 72 214 1 1
PHLPP1 PTPRD 0 0 0 156 1 1
PHLPP1 CDK4 0 0 137 214 1 2
PHLPP1 ENSG00000278522 0 0 0 250 1 1
PHLPP1 RAB4A 0 0 0 169 1 1
PHLPP1 PRKCE 0 0 90 251 1 1
PHLPP1 STAT3 0 0 171 189 1 2
PHLPP1 EZH2 0 0 195 219 1 2
PHLPP1 SNX12 0 0 66 179 1 1
PHLPP1 TYW1 0 0 108 163 1 1
PHLPP1 CDK14 0 0 0 162 1 1
PHLPP1 TRIM23 0 0 0 169 1 1
PHLPP1 NET1 0 0 0 161 1 1
PHLPP1 CAMKK2 0 0 96 221 1 2
PHLPP1 MRPL42 0 0 107 260 1 1
PHLPP1 DIRAS1 0 0 0 268 1 1
PHLPP1 PAK1 0 0 54 171 1 2
PHLPP1 ARL17A 0 0 0 169 1 1
PHLPP1 WSCD2 0 0 0 158 1 1
PHLPP1 RASSF6 0 0 67 170 1 1
PHLPP1 ENSG00000272822 0 0 0 169 1 1
PHLPP1 POTED 0 0 0 250 1 1
PHLPP1 USP28 0 0 167 238 1 1
PHLPP1 GNB5 0 0 53 249 1 1
PHLPP1 RALGPS1 0 0 0 191 1 1
PHLPP1 ITGB1 128 0 0 182 1 1
PHLPP1 ENSG00000255863 0 0 0 169 1 1
PHLPP1 RC3H1 0 0 0 157 1 1
PHLPP1 PPM1G 0 0 298 203 1 1
PHLPP1 KIF16B 0 0 53 171 1 1
PHLPP1 VRTN 0 0 117 206 1 1
PHLPP1 TEAD3 0 0 0 223 1 1
PHLPP1 RHOB 0 0 59 263 1 1
PHLPP1 PPP2R5A 0 0 225 261 1 1
PHLPP1 LLGL1 0 0 0 565 1 1
PHLPP1 STK32A 0 0 0 209 1 1
PHLPP1 BOLA2B 0 0 0 248 1 1
PHLPP1 PIK3R5 0 0 164 163 1 1
PHLPP1 FKBP5 679 0 967 989 1 1
PHLPP1 GDPD4 0 0 0 179 1 1
PHLPP1 RAP2B 0 0 0 268 1 1
PHLPP1 PTPRJ 0 0 427 475 1 1
PHLPP1 RERG 0 0 0 268 1 1
PHLPP1 ELFN2 0 0 116 192 1 1
PHLPP1 CDK6 0 0 95 176 1 2
PHLPP1 PAK2 0 0 0 159 1 1
PHLPP1 BCKDK 0 0 0 200 1 1
PHLPP1 RAPGEF1 0 0 0 191 1 1
PHLPP1 ARL4D 0 0 0 169 1 1
PHLPP1 ARL9 0 0 0 169 1 1
PHLPP1 SKP2 130 0 213 302 1 2
PHLPP1 ZNF594 0 0 152 185 1 1
PHLPP1 TMEM167B 0 0 166 165 1 1
PHLPP1 ACAP2 0 0 208 226 1 1
PHLPP1 CMBL 0 0 95 186 1 2
PHLPP1 SHANK2 0 0 0 151 1 1
PHLPP1 RASSF2 0 0 129 192 1 1
PHLPP1 SMARCB1 0 0 0 153 1 1
PHLPP1 FKBP1A 0 0 451 486 1 2
PHLPP1 NR3C1 0 0 157 175 1 1
PHLPP1 KCTD20 0 0 144 330 1 1
PHLPP1 VANGL2 0 0 199 339 1 1
PHLPP1 RPS6KB2 0 0 67 342 1 2
PHLPP1 PPP1R10 0 0 404 404 1 1
PHLPP1 HIST2H3PS2 0 0 113 164 1 1
PHLPP1 TNS1 0 0 334 334 1 1
PHLPP1 PAK3 0 0 0 159 1 1
PHLPP1 ACAP3 0 0 134 239 1 1
PHLPP1 GNAS 0 0 0 242 1 1
PHLPP1 ARHGEF9 0 0 0 179 1 1
PHLPP1 RPTOR 0 0 333 516 1 2
PHLPP1 PDE2A 0 0 0 333 1 1
PHLPP1 POTEJ 0 0 0 460 1 1
PHLPP1 SOS2 0 0 66 511 1 1
PHLPP1 ARL11 0 0 0 169 1 1
PHLPP1 MYL12A 0 0 0 171 1 1
PHLPP1 CHEK2 0 0 55 151 1 1
PHLPP1 ARL5C 0 0 0 169 1 1
PHLPP1 CASP9 0 0 143 158 1 2
PHLPP1 ARL17B 0 0 0 169 1 1
PHLPP1 AKT1S1 0 0 325 326 1 1
PHLPP1 ENSG00000233917 0 0 0 250 1 1
PHLPP1 SLC9A8 0 0 134 299 1 1
PHLPP1 PPAN 0 0 0 207 1 1
PHLPP1 CHEK1 0 0 123 186 1 2
PHLPP1 MYL7 0 0 0 181 1 1
PHLPP1 PLCG1 0 0 46 214 1 1
PHLPP1 RHOT1 0 0 0 172 1 1
PHLPP1 MAPK12 0 0 0 333 1 1
PHLPP1 SEPHS1 0 0 82 289 1 1
PHLPP1 PLCB4 0 0 107 150 1 1
PHLPP1 TSC1 0 0 182 181 1 2
PHLPP1 BCL2L11 0 0 213 213 1 2
PHLPP1 CSNK1A1 270 0 61 316 1 1
PHLPP1 FKBP3 0 0 145 152 1 1
PHLPP1 CABLES1 0 0 66 248 1 1
PHLPP1 USP4 0 0 143 193 1 1
PHLPP1 WDFY2 0 0 127 218 1 1
PHLPP1 SPOP 0 0 208 236 1 1
PHLPP1 ADARB2 0 0 46 235 1 1
PHLPP1 FAM32A 0 0 66 165 1 1
PHLPP1 CAPN2 0 0 234 280 1 2
PHLPP1 KDM4A 0 0 0 176 1 1
PHLPP1 SNX27 488 0 138 722 1 1
PHLPP1 RASD1 0 0 67 288 1 1
PHLPP1 VSNL1 0 0 0 154 1 1
PHLPP1 CFL2 0 0 0 161 1 1
PHLPP1 ISL2 0 0 0 207 1 1
PHLPP1 DEPDC5 0 0 125 169 1 1
PHLPP1 SNX3 0 0 0 160 1 1
PHLPP1 RPAP3 129 0 0 174 1 1
PHLPP1 RHOQ 0 0 65 189 1 1
PHLPP1 LLGL2 0 0 0 197 1 1
PHLPP1 ERAS 0 0 0 268 1 1
PHLPP1 HSPA8 0 0 203 257 1 2
PHLPP1 TAF1B 0 0 86 184 1 1
PHLPP1 RHOA 0 0 113 305 1 2
PHLPP1 SIRT7 0 0 122 202 1 2
PHLPP1 PDK2 0 0 203 337 1 1
PHLPP1 STK4 0 0 142 324 1 1
PHLPP1 RHOG 0 0 0 209 1 1
PHLPP1 SEMA4A 0 0 0 160 1 1
PHLPP1 LSM1 0 0 0 179 1 1
PHLPP1 HIC2 0 0 108 205 1 1
PHLPP1 DYRK2 0 0 0 160 1 1
PHLPP1 TFEB 0 0 122 184 1 2
PHLPP1 ANKRD2 0 0 60 159 1 1
PHLPP1 FBXW7 0 0 125 154 1 2
PHLPP1 ARL6 0 0 0 169 1 1
PHLPP1 HSFX2 0 0 0 192 1 1
PHLPP1 ZCCHC2 0 0 405 434 1 1
PHLPP1 INS 0 0 370 370 1 2
PHLPP1 ACTB 0 0 273 591 1 2
PHLPP1 FOCAD 0 0 101 180 1 1
PHLPP1 STUB1 270 0 202 392 1 2
PHLPP1 DNMT1 0 0 81 181 1 2
PHLPP1 GAS2L3 0 0 108 172 1 1
PHLPP1 HACE1 0 0 0 197 1 1
PHLPP1 RBX1 0 0 136 198 1 1
PHLPP1 PPM1D 0 0 258 293 1 1
PHLPP1 TSC2 0 0 391 484 1 2
PHLPP1 TRIM50 0 0 90 172 1 1
PHLPP1 BOLA2-SMG1P6 0 0 0 248 1 1
PHLPP1 STK3 0 0 57 200 1 1
PHLPP1 CDKN1B 0 0 432 432 1 2
PHLPP1 GLTP 0 0 231 236 1 1
PHLPP1 PPP1R18 0 0 107 168 1 1
PHLPP1 GPCPD1 0 0 0 281 1 1
PHLPP1 RHOH 0 0 0 169 1 1
PHLPP1 PDE9A 0 0 66 350 1 1
PHLPP1 PTPN7 0 0 0 171 1 1
PHLPP1 INPP5J 0 0 177 216 1 1
PHLPP1 A26B3 0 0 0 250 1 1
PHLPP1 USP1 757 0 617 904 1 1
PHLPP1 RASSF1 0 0 134 188 1 1
PHLPP1 ARPP19 0 0 163 247 1 1
PHLPP1 DNMBP 0 0 0 163 1 1
PHLPP1 WBSCR22 271 0 0 283 1 1
PHLPP1 CADM1 0 0 48 150 1 1
PHLPP1 IQGAP3 0 0 0 162 1 1
PHLPP1 SRSF7 0 0 0 159 1 1
PHLPP1 ZBTB24 0 0 107 203 1 1
PHLPP1 EIF2AK3 0 0 181 198 1 2
PHLPP1 TEN1-CDK3 0 0 0 162 1 1
PHLPP1 PDZD8 0 0 0 188 1 1
PHLPP1 SPTAN1 0 0 82 162 1 1
PHLPP1 KDM6A 0 0 66 338 1 1
PHLPP1 KDM4B 0 0 0 176 1 1
PHLPP1 SRC 0 0 247 290 1 2
PHLPP1 RASGEF1B 0 0 0 191 1 1
PHLPP1 ACTL6A 0 0 0 179 1 1
PHLPP1 BRAP 270 0 155 588 1 1
PHLPP1 RAB25 0 0 0 169 1 2
PHLPP1 GPN2 0 0 0 169 1 1
PHLPP1 IRS4 270 0 0 286 1 1
PHLPP1 DOCK2 0 0 0 180 1 1
PHLPP1 ENSA 0 0 155 229 1 1
PHLPP1 MAP3K1 0 0 90 267 1 1
PHLPP1 CDK15 0 0 0 162 1 1
PHLPP1 SNX7 0 0 57 171 1 1
PHLPP1 DSTN 0 0 0 161 1 1
PHLPP1 ERBB2 0 0 294 294 1 2
PHLPP1 ELAC1 0 0 107 179 1 1
PHLPP1 GSK3A 0 0 574 593 1 1
PHLPP1 USP3 0 0 108 163 1 1
PHLPP1 RHOC 0 0 0 249 1 1
PHLPP1 PIKFYVE 0 0 96 236 1 2
PHLPP1 RPF2 0 0 95 173 1 1
PHLPP1 IKBKB 0 0 145 197 1 2
PHLPP1 USP46 776 0 596 911 1 1
PHLPP1 PDK3 0 0 0 200 1 1
PHLPP1 UBR2 0 0 0 159 1 1
PHLPP1 PPP2R4 0 0 594 600 1 1
PHLPP1 ARHGEF26 0 0 0 161 1 1
PHLPP1 SPEN 0 0 195 223 1 1
PHLPP1 AKT1 675 900 980 999 1 2
PHLPP1 ARL5A 0 0 0 169 1 1
PHLPP1 CAPN1 0 0 402 422 1 2
PHLPP1 CDC42BPA 0 0 0 170 1 1
PHLPP1 UBE3A 0 0 58 152 1 1
PHLPP1 ACTL8 0 0 0 250 1 1
PHLPP1 TEAD2 0 0 0 223 1 1
PHLPP1 ZNF264 0 0 125 159 1 1
PHLPP1 SYNE2 0 0 45 293 1 1
PHLPP1 SGK3 0 0 108 373 1 1
PHLPP1 TPD52 0 0 166 190 1 1
PHLPP1 SEPHS2 0 0 63 223 1 1
PHLPP1 ARL15 0 0 0 169 1 1
PHLPP1 GNAL 0 0 0 242 1 1
PHLPP1 PEBP1 0 0 134 202 1 1
PHLPP1 PNPLA6 0 0 61 278 1 1
PHLPP1 CDK3 0 0 0 162 1 1
PHLPP1 POTEB2 0 0 0 250 1 1
PHLPP1 FNIP2 0 0 158 187 1 1
PHLPP1 ITCH 0 0 87 159 1 1
PHLPP1 STK32C 0 0 0 209 1 1
PHLPP1 ITK 0 0 91 594 1 1
PHLPP1 PLA2G12A 0 0 68 251 1 1
PHLPP1 TRAP1 0 0 0 170 1 2
PHLPP1 PIK3R2 0 0 251 250 1 1
PHLPP1 HMG20A 0 0 90 353 1 1
PHLPP1 PPP6R1 0 0 0 158 1 1
PHLPP1 CNR1 0 0 123 156 1 1
PHLPP1 AGTPBP1 131 0 0 150 1 1
PHLPP1 DDX53 0 0 0 152 1 1
PHLPP1 RHEBL1 0 0 0 268 1 1
PHLPP1 MINK1 0 0 137 183 1 1
PHLPP1 MAP3K14 0 0 0 227 1 1
PHLPP1 CDK13 0 0 0 161 1 1
PHLPP1 RHOF 0 0 0 169 1 1
PHLPP1 AZIN1 0 0 59 203 1 1
PHLPP1 RND3 0 0 61 192 1 1
PHLPP1 TMPRSS2 0 0 232 231 1 1
PHLPP1 CALN1 0 0 0 175 1 1
PHLPP1 PIK3C2G 0 0 125 191 1 1
PHLPP1 RAB7A 0 0 85 192 1 2
PHLPP1 USP26 0 0 182 191 1 1
PHLPP1 AKAP5 0 0 96 166 1 1
PHLPP1 HSF2 0 0 0 232 1 1
PHLPP1 RCC1 0 0 0 227 1 1
PHLPP1 ARL16 0 0 0 169 1 1
PHLPP1 RPS6KB1 270 0 469 715 1 2
PHLPP1 REM1 0 0 0 277 1 1
PHLPP1 NCOR1 0 0 120 189 1 1
PHLPP1 CDK1 0 0 143 251 1 2
PHLPP1 KCNQ4 0 0 0 171 1 1
PHLPP1 LPGAT1 0 0 142 175 1 1
PHLPP1 NTRK1 0 0 57 150 1 1
PHLPP1 RERGL 0 0 0 268 1 1
PHLPP1 RALGPS2 0 0 0 191 1 1
PHLPP1 SGK1 0 0 254 474 1 2
PHLPP1 IRS1 0 0 380 405 1 2
PHLPP1 CC2D1A 0 0 140 158 1 1
PHLPP1 SLC9A3R1 297 0 352 525 1 1
PHLPP1 MAGI2 0 0 137 501 1 1
PHLPP1 DNAJC27 0 0 0 169 1 1
PHLPP1 PDPK1 0 0 342 500 1 2
PHLPP1 RIMKLB 0 0 90 184 1 1
PHLPP1 RAB14 0 0 0 169 1 1
PHLPP1 RBM20 0 0 74 176 1 1
PHLPP1 RRAS2 0 0 0 483 1 1
PHLPP1 PPM1M 0 0 390 431 1 1
PHLPP1 RNASEL 0 0 0 163 1 1
PHLPP1 PTPN2 0 0 57 200 1 2
PHLPP1 DOCK5 0 0 0 180 1 1
PHLPP1 ACTL7A 0 0 0 250 1 1
PHLPP1 E2F3 0 0 0 155 1 1
PHLPP1 NPPC 0 0 0 188 1 1
PHLPP1 MARK2 131 0 66 153 1 1
PHLPP1 MASTL 0 0 242 297 1 1
PHLPP1 DOCK4 0 0 0 180 1 1
PHLPP1 GNB4 0 0 0 312 1 1
PHLPP1 CNTN2 0 0 66 156 1 1
PHLPP1 ACTR1A 0 0 73 275 1 1
PHLPP1 CD200 0 0 562 571 1 1
PHLPP1 CERK 0 0 134 312 1 1
PHLPP1 DLG4 0 0 161 202 1 2
PHLPP1 PREX1 0 0 46 266 1 1
PHLPP1 DYRK1B 0 0 0 160 1 1
PHLPP1 HCAR1 0 0 57 189 1 1
PHLPP1 AREL1 0 0 0 150 1 1
PHLPP1 SRSF3 0 0 0 159 1 1
PHLPP1 TBC1D8 0 0 96 180 1 1
PHLPP1 PPP3R1 0 0 64 167 1 1
PHLPP1 MRAS 0 0 0 268 1 1
PHLPP1 KDM4C 0 0 46 180 1 1
PHLPP1 TEAD1 0 0 56 235 1 1
PHLPP1 PTPN20A 0 0 47 176 1 1
PHLPP1 DIRAS2 0 0 0 283 1 1
PHLPP1 PKN1 0 0 56 223 1 1
PHLPP1 RIPK4 0 0 0 163 1 1
PHLPP1 PKN3 0 0 0 211 1 1
PHLPP1 PRKCA 0 0 247 253 1 1
PHLPP1 RASL11B 0 0 0 268 1 1
PHLPP1 GEM 0 0 0 268 1 1
PHLPP1 GDE1 0 0 0 179 1 1
PHLPP1 MST1R 0 0 0 174 1 1
PHLPP1 MAP1LC3B 0 0 123 231 1 2
PHLPP1 RPRD1A 0 0 0 188 1 1
PHLPP1 ZFP14 0 0 155 214 1 1
PHLPP1 UBC 0 0 0 188 1 2
PHLPP1 TEAD4 0 0 0 223 1 1
PHLPP1 SERPINB5 0 0 93 192 1 1
PHLPP1 ILKAP 0 0 392 260 1 1
PHLPP1 MLLT1 0 0 47 153 1 1
PHLPP1 HSF4 0 0 0 192 1 1
PHLPP1 SMTNL1 0 0 0 232 1 1
PHLPP1 YAP1 0 0 124 175 1 2
PHLPP1 TANC2 0 0 0 189 1 1
PHLPP1 INPP4A 0 0 240 304 1 1
PHLPP1 PPM1J 0 0 324 427 1 1
PHLPP1 PTCHD2 0 0 100 156 1 1
PHLPP1 PIM2 0 0 453 486 1 1
PHLPP1 ESR1 0 0 155 154 1 2
PHLPP1 PDE10A 0 0 0 333 1 1
PHLPP1 PDK4 0 0 0 200 1 1
PHLPP1 ACTBL2 0 0 0 250 1 1
PHLPP1 MAP3K4 0 0 71 238 1 1
PHLPP1 CDKN2C 0 0 64 150 1 1
PHLPP1 PPM1A 0 0 292 326 1 1
PHLPP1 MAPK11 0 0 0 333 1 1
PHLPP1 FGD1 0 0 44 169 1 1
PHLPP1 USP49 0 0 233 249 1 1
PHLPP1 BECN1 0 0 218 235 1 2
PHLPP1 CARD11 0 0 123 300 1 1
PHLPP1 RHOBTB3 0 0 0 169 1 1
PHLPP1 REM2 0 0 0 268 1 1
PHLPP1 POTEH 0 0 0 250 1 1
PHLPP1 POTEC 0 0 0 250 1 1
PHLPP1 ALPK2 0 0 154 153 1 1
PHLPP1 DEPTOR 0 0 265 291 1 2
PHLPP1 ZNF490 0 0 141 174 1 1
PHLPP1 PTPN18 0 0 0 180 1 1
PHLPP1 PRKAR1A 0 0 0 555 1 2
PHLPP1 RHOD 0 0 0 169 1 1
PHLPP1 RND2 0 0 0 189 1 1
PHLPP1 GNB3 0 0 0 312 1 1
PHLPP1 THEM4 0 0 375 375 1 1
PHLPP1 PKN2 0 0 74 238 1 1
PHLPP1 KRAS 0 0 295 620 1 2
PHLPP1 NEBL 0 0 74 169 1 1
PHLPP1 MLST8 0 0 289 333 1 1
PHLPP1 AKAP3 0 0 75 331 1 1
PHLPP1 GSK3B 270 0 161 480 1 2
PHLPP1 CDKN2A 0 0 161 238 1 2
PHLPP1 PPP6C 0 0 150 306 1 1
PHLPP1 SCRIB 837 0 250 881 1 1
PHLPP1 PTGES3 0 0 134 156 1 1
PHLPP1 PIK3CD 0 0 276 330 1 1
PHLPP1 INPP4B 0 0 504 544 1 1
PHLPP1 GPR126 0 0 0 189 1 1
PHLPP1 RASA2 0 0 0 210 1 1
PHLPP1 TBC1D7 270 0 222 460 1 2
PHLPP1 KIDINS220 0 0 92 158 1 1
PHLPP1 ERBB3 0 0 235 235 1 1
PHLPP1 RASGRP4 0 0 0 191 1 1
PHLPP1 CASP3 0 0 261 261 1 2
PHLPP1 AGPAT9 0 0 55 199 1 1
PHLPP1 RNF152 0 0 157 176 1 1
PHLPP1 MAPK15 0 0 53 269 1 1
PHLPP1 ZFP28 0 0 134 253 1 1
PHLPP1 TONSL 0 0 74 159 1 1
PHLPP1 RASGRF1 0 0 74 219 1 1
PHLPP1 PPM1B 0 0 335 200 1 1
PHLPP1 TGFBRAP1 0 0 0 152 1 1
PHLPP1 RHOBTB1 0 0 0 169 1 1
PHLPP1 ARL8A 0 0 0 169 1 1
PHLPP1 CTNNB1 0 0 284 284 1 2
PHLPP1 HRAS 0 0 264 603 1 2
PHLPP1 ENSG00000258989 0 0 0 211 1 1
PHLPP1 FAM160B1 0 0 137 257 1 1
PHLPP1 KLK3 0 0 193 193 1 1
PHLPP1 BAI3 0 0 108 185 1 1
PHLPP1 ARF3 0 0 0 169 1 1
PHLPP1 SEC11C 0 0 180 190 1 1
PHLPP1 VRK1 0 0 67 167 1 1
PHLPP1 POTEM 0 0 0 250 1 1
PHLPP1 ISL1 0 0 0 156 1 1
PHLPP1 DHX32 0 0 104 194 1 1
PHLPP1 NEDD4 0 0 123 174 1 2
PHLPP1 PLEK 0 0 652 661 1 1
PHLPP1 SCPEP1 0 0 160 204 1 1
PHLPP1 GNA13 0 0 52 396 1 1
PHLPP1 HSFX1 0 0 0 192 1 1
PHLPP1 MAP3K2 0 0 0 335 1 1
PHLPP1 PIK3C3 0 0 112 179 1 2
PHLPP1 MTOR 0 0 459 702 1 2
PHLPP1 MAPKAP1 0 0 157 235 1 1
PHLPP1 KCNH1 0 0 49 191 1 1
PHLPP1 RRAS 0 0 45 274 1 1
PHLPP1 ZNF606 0 0 150 309 1 1
PHLPP1 HSF1 0 0 0 232 1 2
PHLPP1 IQGAP1 0 0 0 162 1 1
PHLPP1 GRID2IP 0 0 0 187 1 1
PHLPP1 RHOJ 0 0 0 169 1 1
PHLPP1 INPPL1 0 0 311 341 1 1
PHLPP1 MAP1LC3B2 0 0 0 159 1 1
PHLPP1 USP9X 0 0 155 176 1 1
PHLPP1 ARL14 0 0 0 169 1 1
PHLPP1 CREB1 0 0 218 227 1 2
PHLPP1 RHOBTB2 0 0 0 169 1 1
PHLPP1 GLRA3 0 0 95 308 1 1
PHLPP1 MAP2K7 0 0 234 234 1 1
PHLPP1 SMG1 0 0 0 248 1 1
PHLPP1 ARL5B 0 0 0 169 1 1
PHLPP1 FKBP8 0 0 218 218 1 1
PHLPP1 ERG 0 0 81 218 1 1
PHLPP1 ARHGEF37 0 0 0 163 1 1
PHLPP1 GAPDH 0 0 293 293 1 2
PHLPP1 CCDC85A 0 0 108 173 1 1
PHLPP1 LRRCC1 0 0 55 159 1 1
PHLPP1 PIGP 0 0 49 261 1 1
PHLPP1 GNAQ 0 0 84 276 1 1
PHLPP1 PIK3R3 0 0 229 228 1 1
PHLPP1 RICTOR 0 0 459 507 1 2
PHLPP1 GDPD1 0 0 0 179 1 1
PHLPP1 TAPT1 0 0 108 234 1 1
PHLPP1 ILK 0 0 181 240 1 1
PHLPP1 PPP5C 131 0 82 218 1 1
PHLPP1 SHISA7 0 0 124 150 1 1
PHLPP1 BOLA2 0 0 0 248 1 1
PHLPP1 BRCA1 0 0 155 204 1 2
PHLPP1 STK11 0 0 158 208 1 2
PHLPP1 CNGB1 0 0 49 307 1 1
PHLPP1 DAB2IP 0 0 119 172 1 2
PHLPP1 MYL9 0 0 0 190 1 1
PHLPP1 VPS39 0 0 0 186 1 1
PHLPP1 ACTA1 0 0 0 460 1 1
PHLPP1 LETMD1 0 0 100 156 1 1
PHLPP1 CTSA 0 0 156 348 1 1
PHLPP1 TGIF2LX 0 0 0 211 1 1
PHLPP1 NCOR2 0 0 146 213 1 1
PHLPP1 RAF1 0 0 231 266 1 2
PHLPP1 EGFR 0 0 310 309 1 2
PHLPP1 PPP1CC 0 0 81 190 1 1
PHLPP1 MYL10 0 0 0 254 1 1
PHLPP1 SLC2A1 0 0 108 179 1 2
PHLPP1 INSIG1 0 0 0 208 1 1
PHLPP1 RAB2A 0 0 0 169 1 1
PHLPP1 ZCCHC8 0 0 74 157 1 1
PHLPP1 RASGRP1 0 0 0 191 1 1
PHLPP1 CNNM2 0 0 60 158 1 1
PHLPP1 DOCK3 0 0 0 197 1 1
PHLPP1 MDM2 0 0 438 438 1 2
PHLPP1 PRDM10 0 0 74 165 1 1
PHLPP1 TP53 0 0 341 341 1 2
PHLPP1 POTEG 0 0 0 250 1 1
PHLPP1 RASGRP3 0 0 49 198 1 1
PHLPP1 CPVL 0 0 0 243 1 1
PHLPP1 RHBDL3 0 0 0 183 1 1
PHLPP1 ITGB8 0 0 67 195 1 1
PHLPP1 PTPN22 0 0 73 203 1 1
PHLPP1 ZNF532 0 0 134 187 1 1
PHLPP1 SERPINH1 0 0 450 450 1 1
PHLPP1 PRKAR2A 0 0 0 555 1 1
PHLPP1 CDH3 0 0 0 246 1 1
PHLPP1 ACTR8 0 0 0 179 1 1
PHLPP1 CLU 0 0 76 158 1 2
PHLPP1 HUWE1 0 0 44 214 1 1
PHLPP1 CALM3 0 0 0 230 1 1
PHLPP1 ACTL7B 0 0 0 250 1 1
PHLPP1 PTPN4 0 0 0 155 1 1
PHLPP1 GNAT1 0 0 0 519 1 1
PHLPP1 PLEKHA8 0 0 150 156 1 1
PHLPP1 NAA10 0 0 391 391 1 1
PHLPP1 ENSG00000267318 0 0 0 209 1 1
PHLPP1 RAP1B 0 0 47 273 1 1
PHLPP1 EP300 0 0 134 175 1 2
PHLPP1 KCTD17 0 0 142 247 1 1
PHLPP1 CUL1 0 0 226 288 1 1
PHLPP1 TRIM41 0 0 210 228 1 1
PHLPP1 BBS10 0 0 0 206 1 1
PHLPP1 RAP2A 0 0 0 268 1 1
PHLPP1 GNB2 0 0 66 330 1 1
PHLPP1 ALB 0 0 141 175 1 2
PHLPP1 SGK2 0 0 0 324 1 1
PHLPP1 CHSY1 0 0 90 165 1 1
PHLPP1 MAGI3 0 0 67 239 1 1
PHLPP1 ACTR1B 0 0 0 250 1 1
PHLPP1 PDE4A 0 0 0 364 1 1
PHLPP1 DAAM1 0 0 0 171 1 1
PHLPP1 TTC5 0 0 108 172 1 1
PHLPP1 CDH1 161 0 181 528 1 2
PHLPP1 PRKCZ 0 0 141 180 1 1
PHLPP1 CDK16 0 0 63 181 1 1
PHLPP1 ZNF862 0 0 150 183 1 1
PHLPP1 CAP2 0 0 0 818 1 1
PHLPP1 SGK494 0 0 0 402 1 1
PHLPP1 FKBP4 128 0 636 669 1 1
PHLPP1 PDE4D 0 0 0 364 1 1
PHLPP1 ACTC1 0 0 0 460 1 1
PHLPP1 MAP2K4 0 0 120 180 1 1
PHLPP1 API5 0 0 151 174 1 1
PHLPP1 PRKAR1B 0 0 0 555 1 1
PHLPP1 KCTD9 0 0 0 156 1 1
PHLPP1 FGF18 0 0 205 223 1 1
PHLPP1 WDR47 0 0 133 152 1 1
PHLPP1 MAPK8 168 0 160 271 1 2
PHLPP1 MARCH4 0 0 94 192 1 1
PHLPP1 RPRD1B 0 0 95 206 1 1
PHLPP1 MYLPF 0 0 0 181 1 1
PHLPP1 SRPK1 0 0 478 491 1 1
PHLPP1 GDPD5 0 0 0 179 1 1
PHLPP1 PPP2R5B 0 0 324 350 1 1
PHLPP1 GDPD3 0 0 0 179 1 1
PHLPP1 ARHGEF3 0 0 0 161 1 1
PHLPP1 STAB2 0 0 45 170 1 1
PHLPP1 PDE6B 0 0 0 333 1 1
PHLPP1 HSP90B1 0 0 0 170 1 1
PHLPP1 DYRK3 0 0 0 160 1 1
PHLPP1 PTPRK 0 0 0 153 1 1
PHLPP1 PIK3R1 0 0 278 278 1 1
PHLPP1 IGSF3 0 0 81 178 1 1
PHLPP1 CCNJL 0 0 170 206 1 1
PHLPP1 TIAM2 0 0 0 163 1 1
PHLPP1 EGF 0 0 250 250 1 2
PHLPP1 PTPN3 0 0 0 187 1 1
PHLPP1 GNAZ 0 0 74 410 1 1
PHLPP1 PDP1 0 0 721 735 1 1
PHLPP1 RAC3 0 0 0 345 1 2
PHLPP1 PPM1L 0 0 93 216 1 1
PHLPP1 DGKZ 0 0 113 162 1 1
PHLPP1 CAMKK1 0 0 0 174 1 1
PHLPP1 SPTLC3 0 0 207 213 1 1
PHLPP1 PIK3CG 0 0 325 375 1 1
PHLPP1 BOK 0 0 0 207 1 1
PHLPP1 VWA8 0 0 0 232 1 1
PHLPP1 EIF2AK1 0 0 61 179 1 1
PHLPP1 CCNA2 0 0 95 152 1 1
PHLPP1 TEX2 0 0 104 165 1 1
PHLPP1 ARL4A 0 0 0 187 1 1
PHLPP1 TRIM11 270 0 71 322 1 1
PHLPP1 JUN 0 0 264 280 1 2
PHLPP1 WDR31 0 0 0 310 1 1
PHLPP1 ACTR3 0 0 0 179 1 1
PHLPP1 RABL2A 0 0 0 169 1 1
PHLPP1 ARHGEF16 0 0 0 230 1 1
PHLPP1 ACTR3C 0 0 0 179 1 1
PHLPP1 TPP2 0 0 117 201 1 1
PHLPP1 TBC1D4 0 0 215 253 1 1
PHLPP1 TBL1X 0 0 169 199 1 1
PHLPP1 INSIG2 0 0 0 208 1 1
PHLPP1 PP2D1 0 0 270 172 1 1
PHLPP1 MCM3AP 0 0 0 167 1 1
PHLPP1 ARL10 0 0 0 169 1 1
PHLPP1 ENSG00000270024 0 0 107 373 1 1
PHLPP1 PRKACB 0 0 92 485 1 1
PHLPP1 PPM1F 0 0 306 195 1 1
PHLPP1 NOS1AP 0 0 108 203 1 1
PHLPP1 KIAA0020 0 0 91 182 1 1
PHLPP1 UCHL1 0 0 180 179 1 2
PHLPP1 GAP43 0 0 55 172 1 1
PHLPP1 IRS2 0 0 233 250 1 1
PHLPP1 PUM2 0 0 0 188 1 1
PHLPP1 RAP2C 0 0 0 268 1 1
PHLPP1 KIAA1109 0 0 0 372 1 1
PHLPP1 GNA12 0 0 0 389 1 1
PHLPP1 KIAA1468 0 0 341 451 1 1
PHLPP1 CDKN1A 0 0 170 169 1 2
PHLPP1 WSCD1 0 0 0 180 1 1
PHLPP1 NDUFAF6 0 0 162 277 1 1
PHLPP1 AR 0 0 457 457 1 2
PHLPP1 RALB 0 0 0 268 1 2
PHLPP1 GNB1 0 0 0 312 1 1
PHLPP1 WDR48 787 0 611 915 1 1
PHLPP1 ATRNL1 0 0 117 354 1 1
PHLPP1 ENSG00000271810 0 0 0 286 1 1
PHLPP1 RASL12 0 0 0 268 1 1
PHLPP1 PLEKHF2 0 0 139 155 1 1
PHLPP1 UMPS 0 0 0 181 1 1
PHLPP1 C2CD4C 0 0 132 222 1 1
PHLPP1 RHOV 0 0 0 169 1 1
PHLPP1 ATF2 0 0 0 168 1 1
PHLPP1 HSP90AA1 0 0 294 590 1 2
PHLPP1 DDX4 0 0 0 183 1 1
PHLPP1 STK38 0 0 143 282 1 1
PHLPP1 RND1 0 0 0 169 1 1
PHLPP1 MAPK3 0 0 324 530 1 2
PHLPP1 MYL12B 0 0 0 171 1 1
PHLPP1 SQSTM1 0 0 161 161 1 2
PHLPP1 GNA14 0 0 0 242 1 1
PHLPP1 TIAM1 0 0 45 166 1 1
PHLPP1 AKNAD1 0 0 157 156 1 1
PHLPP1 CNBD2 0 0 0 497 1 1
PHLPP1 RASGRF2 0 0 0 191 1 1
PHLPP1 PIK3C2A 0 0 103 170 1 1
PHLPP1 MRPL16 0 0 0 176 1 1
PHLPP1 PPAN-P2RY11 0 0 0 207 1 1
PHLPP1 USP7 0 0 202 234 1 1
PHLPP1 UBR1 0 0 0 159 1 1
PHLPP1 PRKCD 0 0 0 211 1 2
PHLPP1 FOXP3 0 0 149 191 1 2
PHLPP1 ZNF488 0 0 0 163 1 1
PHLPP1 RAB11A 0 0 55 181 1 2
PHLPP1 RAC2 0 0 103 387 1 1
PHLPP1 NKX3-1 0 0 233 232 1 1
PHLPP1 SKP1 0 0 204 236 1 2
PHLPP1 GSG1 0 0 57 271 1 1
PHLPP1 DNAJB1 0 0 108 226 1 2
PHLPP1 MAP3K19 0 0 0 227 1 1
PHLPP1 USP12 750 0 491 875 1 2
PHLPP1 TP53INP1 0 0 163 177 1 2
PHLPP1 ACTG2 0 0 0 460 1 1
PHLPP1 FMNL1 0 0 0 171 1 1
PHLPP1 SLC2A4 0 0 155 173 1 1
PHLPP1 FOXO3 0 0 392 435 1 2
PHLPP1 CDC42 0 0 141 413 1 2
PHLPP1 TEX35 0 0 194 227 1 1
PHLPP1 PDE4B 0 0 0 364 1 1
PHLPP1 IMPAD1 0 0 86 193 1 1
PHLPP1 ACTL10 0 0 0 250 1 1
PHLPP1 PPM1E 0 0 181 163 1 1
PHLPP1 GLTPD2 0 0 84 163 1 1
PHLPP1 DENR 0 0 57 152 1 1
PHLPP1 SPATA13 0 0 0 262 1 1
PHLPP1 PDE5A 0 0 0 333 1 1
PHLPP1 PPP3CA 0 0 66 239 1 1
PHLPP1 PTPN23 0 0 0 199 1 1
PHLPP1 DDX56 0 0 73 166 1 1
PHLPP1 FOXO4 0 0 122 160 1 1
PHLPP1 HSP90AB1 0 0 48 447 1 2
PHLPP1 CYLD 0 0 194 257 1 1
PHLPP1 EIF4EBP1 0 0 366 366 1 2
PHLPP1 COA1 270 0 0 270 1 1
PHLPP1 BMX 0 0 75 266 1 1
PHLPP1 GDF7 0 0 53 211 1 1
PHLPP1 ARF4 0 0 0 169 1 1
PHLPP1 MTMR4 0 0 59 162 1 1
PHLPP1 CTDP1 0 0 75 163 1 1
PHLPP1 WDR20 675 0 339 784 1 1
PHLPP1 RASD2 0 0 0 268 1 1
PHLPP1 PREX2 0 0 53 289 1 1
PHLPP1 CDK18 0 0 0 162 1 1
PHLPP1 INPP5D 0 0 184 207 1 1
PHLPP1 CAP1 0 0 0 818 1 1
PHLPP1 PPM1H 0 0 371 514 1 1
PHLPP1 RABL2B 0 0 0 169 1 1
PHLPP1 DDX3X 0 0 0 248 1 1
PHLPP1 LCMT2 0 0 170 184 1 1
PHLPP1 CDK12 0 0 0 161 1 1
PHLPP1 CDC42BPB 0 0 0 273 1 1
PHLPP1 KCNH5 0 0 0 184 1 1
PHLPP1 TJP2 0 0 410 411 1 1
PHLPP1 BDNF 0 0 154 153 1 2
PHLPP1 HIPK3 0 0 46 165 1 1
PHLPP1 CABP1 0 0 0 164 1 1
PHLPP1 GNAI2 0 0 0 519 1 1
PHLPP1 DAAM2 0 0 0 171 1 1
PHLPP1 ATP11C 0 0 0 160 1 1
PHLPP1 PPP2R5C 0 0 134 175 1 1
PHLPP1 MAPK1 0 0 141 403 1 2
PHLPP1 PPP2R1A 129 0 151 273 1 1
PHLPP1 IGF1 0 0 253 252 1 2
PHLPP1 CYTH3 0 0 108 165 1 1
PHLPP1 RAB39A 0 0 0 169 1 1
PHLPP1 BTK 0 0 134 337 1 1
PHLPP1 CUL4B 0 0 116 170 1 1
PHLPP1 PPTC7 0 0 381 442 1 1
PHLPP1 SOS1 0 0 88 523 1 1
PHLPP1 POTEI 0 0 0 460 1 1
PHLPP1 ICMT 0 0 0 200 1 1
PHLPP1 CDK17 0 0 0 162 1 1
PHLPP1 IQGAP2 0 0 0 162 1 1
PHLPP1 VANGL1 0 0 160 199 1 1
PHLPP1 MYL2 0 0 0 254 1 1
PHLPP1 BLNK 0 0 59 204 1 1
PHLPP1 PRKAA1 0 0 0 324 1 2
PHLPP1 ARHGEF7 0 0 441 441 1 1
PHLPP1 CCND1 0 0 263 263 1 2
PHLPP1 ACTA2 0 0 0 460 1 1
PHLPP1 PPM1K 0 0 261 217 1 1
PHLPP1 CNGB3 0 0 60 315 1 1
PHLPP1 MCMBP 131 0 0 150 1 1
PHLPP1 HGNC:9979 285 0 0 301 1 1
PHLPP1 EIF4E 0 0 181 227 1 2
PHLPP1 PPP2CA 0 0 278 317 1 1
PHLPP1 PRKDC 0 0 108 301 1 2
PHLPP1 PIK3C2B 0 0 81 150 1 1
PHLPP1 ACTR10 0 0 0 250 1 1
PHLPP1 RRAD 0 0 0 268 1 1
PHLPP1 USP13 0 0 134 190 1 1
PHLPP1 PLA2G12B 0 0 81 317 1 1
PHLPP1 UBB 0 0 69 211 1 1
PHLPP1 FANCI 270 0 451 591 1 1
PHLPP1 GNB2L1 0 0 109 475 1 1
PHLPP1 PIP5KL1 0 0 147 232 1 1
PHLPP1 ATF7 0 0 0 168 1 1
PHLPP1 RHEB 0 0 293 460 1 2
PHLPP1 MDN1 0 0 0 232 1 1
PHLPP1 PHLPP2 674 800 884 937 1 1
PHLPP1 HPCA 0 0 0 152 1 1
PHLPP1 PPP2R5E 0 0 101 216 1 1
PHLPP1 MAP2K2 0 0 49 225 1 1
PHLPP1 PALLD 0 0 134 222 1 1
PHLPP1 RHOT2 0 0 0 169 1 1
PHLPP1 SYK 0 0 396 424 1 2
PHLPP1 NFKBIA 0 0 122 203 1 2
PHLPP1 PRKG2 0 0 0 262 1 1
PHLPP1 PTPRG 0 0 0 260 1 1
PHLPP1 MAP3K3 0 0 82 363 1 1
PHLPP1 SREBF1 0 0 112 185 1 1
PHLPP1 MAPK14 0 0 90 367 1 2
PHLPP1 CFL1 0 0 46 165 1 1
PHLPP1 PTEN 297 0 817 879 1 2
PHLPP1 DYRK4 0 0 0 160 1 1
PHLPP1 TNFAIP1 0 0 123 151 1 1
PHLPP1 MAPK7 0 0 0 333 1 1
PHLPP1 VEGFA 0 0 170 229 1 2
PHLPP1 PRKAA2 0 0 0 324 1 2
PHLPP1 ACTG1 0 0 0 460 1 1
PHLPP1 WDR7 0 0 193 215 1 1
PHLPP1 ATG7 0 0 210 228 1 2
PHLPP1 VWA1 0 0 163 163 1 1
PHLPP1 EFNB2 273 0 0 278 1 1
PHLPP1 FMN1 0 0 0 172 1 1
PHLPP1 GFAP 0 0 123 254 1 2
PHLPP1 PRKAG3 0 0 0 240 1 1
PHLPP1 ATM 0 0 162 183 1 2
PHLPP1 AIF1L 0 0 0 164 1 1
PHLPP1 GNAI1 0 0 0 519 1 1
PHLPP1 RASL10A 0 0 0 268 1 1
PHLPP1 NEK2 0 0 0 340 1 1
PHLPP1 RPS6KA1 0 0 147 195 1 1
PHLPP1 AKT3 0 900 870 989 1 2
PHLPP1 ZBTB21 0 0 102 191 1 1
PHLPP1 RARA 0 0 172 253 1 2
PHLPP1 RALA 0 0 0 268 1 1
PHLPP1 ARL13B 0 0 0 208 1 1
PHLPP1 DYRK1A 0 0 0 160 1 1
PHLPP1 LRFN2 0 0 81 152 1 1
PHLPP1 DMWD 131 0 107 221 1 1
PHLPP1 ICK 0 0 180 233 1 1
PHLPP1 SUGT1 787 0 162 924 1 1
PHLPP1 TTLL12 0 0 103 165 1 1
PHLPP1 ACTR3B 0 0 0 179 1 1
PHLPP1 PTPRR 0 0 66 213 1 1
PHLPP1 CYTH1 0 0 60 181 1 1
PHLPP1 KSR1 270 0 71 332 1 1
PHLPP1 ATG5 0 0 155 154 1 2
PHLPP1 ACTRT2 0 0 0 250 1 1
PHLPP1 WDR90 0 0 0 160 1 1
PHLPP1 PRKAG2 0 0 0 240 1 1
PHLPP1 PTPRZ1 0 0 0 296 1 1
PHLPP1 PTPN1 0 0 103 258 1 1
PHLPP1 PUM1 0 0 0 188 1 1
PHLPP1 SNX6 271 0 0 271 1 1
PHLPP1 HIPK2 0 0 53 171 1 2
PHLPP1 MCL1 0 0 183 220 1 2
PHLPP1 SIRT1 0 0 150 198 1 2
PHLPP1 HECTD3 0 0 0 150 1 1
PHLPP1 POTEB3 0 0 0 250 1 1
PHLPP1 ZNF432 0 0 139 172 1 1
PHLPP1 MAPK6 0 0 0 260 1 1
PHLPP1 PPP1CA 0 0 134 231 1 1
PHLPP1 RAC1 0 0 95 381 1 2
PHLPP1 ACTL6B 0 0 0 198 1 1
PHLPP1 GNA11 0 0 0 242 1 1
PHLPP1 GNAO1 0 0 0 529 1 1
PHLPP1 PLXNA4 0 0 0 156 1 1
PHLPP1 MET 0 0 113 236 1 2
PHLPP1 RBM15 222 0 173 329 1 1
PHLPP1 PRKCH 0 0 0 211 1 1
PHLPP1 PIK3CB 0 0 323 374 1 1
PHLPP1 CERS6 0 0 134 198 1 1
PHLPP1 ARL4C 0 0 0 169 1 1
PHLPP1 ARF6 0 0 0 169 1 1
PHLPP1 RASL11A 0 0 0 268 1 1
PHLPP1 STK38L 0 0 46 201 1 1
PHLPP1 GNAI3 0 0 67 532 1 2
PHLPP1 RASL10B 0 0 0 268 1 1
PHLPP1 DDX43 0 0 74 206 1 1
PHLPP1 RAB11B 0 0 0 169 1 1
PHLPP1 PTPN11 0 0 99 174 1 1
PHLPP1 DDX24 0 0 0 173 1 1
PHLPP1 PNPLA7 0 0 0 262 1 1
PHLPP1 FOS 0 0 108 195 1 2
PHLPP1 PPM1N 0 0 157 181 1 1
PHLPP1 RAB39B 0 0 0 169 1 1
PHLPP1 FOXO1 0 0 390 403 1 2
PHLPP1 TLN2 0 0 122 151 1 1
PHLPP1 BTRC 486 0 837 918 1 1
PHLPP1 FKBP10 0 0 75 155 1 1
PHLPP1 LANCL1 0 0 119 192 1 1
PHLPP1 GDPD2 0 0 0 179 1 1
PHLPP1 NRAS 0 0 123 527 1 1
PHLPP1 PDE7B 0 0 0 333 1 1
PHLPP1 PDE6A 0 0 0 333 1 1
PHLPP1 CUL3 0 0 123 184 1 2
PHLPP1 CHUK 0 0 142 181 1 1
PHLPP1 PDE6C 0 0 0 333 1 1
PHLPP1 TBC1D1 0 0 157 274 1 1
PHLPP1 CALM2 0 0 0 230 1 1
PHLPP1 PTPN12 0 0 0 171 1 1
PHLPP1 ACTL9 0 0 0 250 1 1
PHLPP1 HDAC1 128 0 90 208 1 2
PHLPP1 RAB42 0 0 0 169 1 1
PHLPP1 CDO1 0 0 54 161 1 1
PHLPP1 PI4KA 0 0 0 182 1 1
PHLPP1 RAB2B 0 0 0 169 1 1
PHLPP1 FBP1 0 0 0 308 1 1
PHLPP1 RAB4B 0 0 0 169 1 1
PHLPP1 GNA15 0 0 0 242 1 1
PHLPP1 CPPED1 0 0 97 180 1 1
PHLPP1 ARHGEF38 0 0 0 163 1 1
PHLPP1 DIRAS3 0 0 0 268 1 2
PHLPP1 SLITRK3 0 0 87 156 1 1
PHLPP1 PRKCQ 0 0 0 211 1 2
PHLPP1 PTPN5 0 0 124 261 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0046872 Molecular Function metal ion binding enables IEA
GO:0017018 Molecular Function myosin phosphatase activity enables IEA
GO:0005515 Molecular Function protein binding enables IPI
GO:0004722 Molecular Function protein serine/threonine phosphatase activity enables IBA
GO:0006915 Biological Process apoptotic process involved_in IEA
GO:0009649 Biological Process entrainment of circadian clock involved_in IEA
GO:0051898 Biological Process negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction involved_in IMP
GO:0046328 Biological Process regulation of JNK cascade involved_in IDA
GO:0043408 Biological Process regulation of MAPK cascade involved_in IMP
GO:0002667 Biological Process regulation of T cell anergy involved_in IEA
GO:0042981 Biological Process regulation of apoptotic process involved_in IDA
GO:1900744 Biological Process regulation of p38MAPK cascade involved_in IDA
GO:0007165 Biological Process signal transduction involved_in IBA
GO:0005737 Cellular Component cytoplasm is_active_in IBA
GO:0005829 Cellular Component cytosol located_in TAS
GO:0043231 Cellular Component intracellular membrane-bounded organelle is_active_in IBA
GO:0005634 Cellular Component nucleus located_in IEA
GO:0005886 Cellular Component plasma membrane located_in IEA
Pathways
Name DB ID
PIP3 activates AKT signaling Reactome R-HSA-1257604
Signal Transduction Reactome R-HSA-162582
Negative regulation of the PI3K/AKT network Reactome R-HSA-199418
Intracellular signaling by second messengers Reactome R-HSA-9006925
Focal adhesion: PI3K-Akt-mTOR-signaling pathway (WP3932) WikiPathways WP3932_r124527
Circadian rhythm genes (WP3594) WikiPathways WP3594_r117682
PI3K-Akt signaling pathway (WP4172) WikiPathways WP4172_r122580
Transcripts
Accession Version MolecularType Name NCBI Comments
NM_194449 4 mRNA None NC_000018 Reference