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CRTC1

CREB regulated transcription coactivator 1
General Information
Name CREB regulated transcription coactivator 1
Alias
  • CREB-regulated transcription coactivator 1
  • Mastermind-like protein 2
  • mucoepidermoid carcinoma translocated protein 1
  • transducer of regulated cAMP response element-binding protein (CREB) 1
Gene_family
organism Homo sapiens
entrez_id 23373
location 19p13.11
transcript_count 2
exon_count 15
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez Enables cAMP response element binding protein binding activity. Involved in positive regulation of transcription by RNA polymerase II. Located in cytosol; nuclear body; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
    Stringdb CREB-regulated transcription coactivator 1; Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX act [...]
    nextProt Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses. May be required for dendritic growth of developing cortical neurons (By similarity). In concert with SIK1, regulates the light-induced entrainment of the circadian clock. In response to light stimulus, coactivates the CREB-mediated transcription of PER1 which plays an important role in the photic entrainment of the circadian clock.
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
CRTC1 BioGRID YWHAQ GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
CRTC1 BioGRID YWHAZ GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
CRTC1 BioGRID YWHAH GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
CRTC1 BioGRID YWHAG GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
CRTC1 BioGRID YWHAE GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
CRTC1 BioGRID YWHAB GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
CRTC1 BioGRID PHF21A GeneID BioGRID Proximity Label-MS
CRTC1 BioGRID KDM1A GeneID BioGRID Proximity Label-MS
CRTC1 BioGRID HDAC1 GeneID BioGRID Proximity Label-MS
CRTC1 BioGRID WAC GeneID BioGRID Co-fractionation
CRTC1 BioGRID VASP GeneID BioGRID Proximity Label-MS
CRTC1 BioGRID TBK1 GeneID BioGRID Biochemical Activity
CRTC1 BioGRID TFG GeneID BioGRID Affinity Capture-Western
CRTC1 BioGRID TRAF3 GeneID BioGRID Affinity Capture-Western
CRTC1 BioGRID ESR1 GeneID BioGRID Affinity Capture-MS
CRTC1 BioGRID CREB1 GeneID BioGRID Two-hybrid
CRTC1 BioGRID BICD2 GeneID BioGRID Proximity Label-MS
CRTC1 BioGRID CBY1 GeneID BioGRID Affinity Capture-MS
CRTC1 BioGRID KIF13B GeneID BioGRID Affinity Capture-MS
CRTC1 BioGRID KCTD3 GeneID BioGRID Affinity Capture-MS
CRTC1 BioGRID XPO1 GeneID BioGRID Affinity Capture-MS
CRTC1 BioGRID SRPK2 GeneID BioGRID Biochemical Activity
CRTC1 BioGRID EP300 GeneID BioGRID Affinity Capture-Western
CRTC1 BioGRID CREBBP GeneID BioGRID Affinity Capture-Western
CRTC1 BioGRID MEIS1 GeneID BioGRID Affinity Capture-Western
CRTC1 BioGRID MAP3K1 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
CRTC1 Protein YWHAG GeneID HPRD
CRTC1 None None None BIND TORC1 interacts with calcineurin. This interaction was modeled on a demonstrated interaction between human TORC1 and bovine calcineurin.
CRTC1 None None None BIND TORC1 interacts with CREB.
StringDB
A B experiments database textmining combined score hadb nhadb
CRTC1 TSC1 0 0 0 158 1 2
CRTC1 SPACA5B 0 0 95 252 1 1
CRTC1 MAML1 0 0 416 422 1 1
CRTC1 ETNK2 0 0 49 170 1 1
CRTC1 SPA17 0 0 195 210 1 1
CRTC1 MGRN1 0 0 0 167 1 1
CRTC1 JUN 0 900 456 943 1 2
CRTC1 TRIM11 0 0 302 302 1 1
CRTC1 PPAN 0 0 123 259 1 1
CRTC1 CRTC3 0 800 804 841 1 1
CRTC1 GM2A 0 0 82 360 1 1
CRTC1 SIK2 0 0 595 738 1 1
CRTC1 ELOVL4 0 0 66 229 1 1
CRTC1 EIF4ENIF1 0 0 95 151 1 1
CRTC1 PER2 0 0 205 408 1 1
CRTC1 CAMK1D 0 0 90 167 1 1
CRTC1 FRMPD4 0 0 49 226 1 1
CRTC1 CALR 0 0 528 528 1 1
CRTC1 NEDD9 0 0 134 152 1 1
CRTC1 CNFN 0 0 116 324 1 1
CRTC1 SS18 0 0 203 203 1 1
CRTC1 SEPT5 0 0 294 346 1 1
CRTC1 DBNDD1 0 0 181 181 1 1
CRTC1 YWHAE 128 0 512 703 1 1
CRTC1 KPNA2 0 0 66 196 1 1
CRTC1 CENPBD1 0 0 261 261 1 1
CRTC1 COBLL1 0 0 207 224 1 1
CRTC1 RFTN1 0 0 107 241 1 1
CRTC1 SIRT7 0 0 170 169 1 2
CRTC1 INSR 0 0 90 154 1 1
CRTC1 SULT6B1 0 0 69 242 1 1
CRTC1 GNRH1 0 0 213 213 1 1
CRTC1 CRTC2 0 800 709 832 1 1
CRTC1 PHOX2A 0 0 0 156 1 1
CRTC1 GNA12 0 0 82 348 1 1
CRTC1 CELF4 0 0 91 263 1 1
CRTC1 TMLHE 0 0 90 489 1 1
CRTC1 CARTPT 0 0 537 581 1 1
CRTC1 RBM14 0 0 307 307 1 1
CRTC1 SYN1 0 0 67 163 1 1
CRTC1 SLC5A11 0 0 0 572 1 1
CRTC1 INS 0 0 306 306 1 2
CRTC1 LIMA1 0 0 67 308 1 1
CRTC1 KIFC2 0 0 0 151 1 1
CRTC1 GRASP 0 0 0 173 1 1
CRTC1 NAA15 0 0 0 252 1 1
CRTC1 SUB1 0 0 306 306 1 1
CRTC1 SIRT3 0 0 194 357 1 2
CRTC1 HDAC4 0 0 193 227 1 2
CRTC1 CRCT1 0 0 391 404 1 1
CRTC1 FRMPD3 0 0 212 520 1 1
CRTC1 CEP72 0 0 131 185 1 1
CRTC1 LASP1 0 0 384 384 1 1
CRTC1 GPR153 0 0 0 325 1 1
CRTC1 PANX2 0 0 66 156 1 1
CRTC1 IL16 0 0 0 158 1 1
CRTC1 REEP5 0 0 0 154 1 1
CRTC1 SPTBN4 0 0 150 223 1 1
CRTC1 SORBS3 0 0 167 193 1 1
CRTC1 BCL9 0 0 108 346 1 1
CRTC1 KAT2A 0 0 70 266 1 1
CRTC1 PBX4 0 0 181 181 1 1
CRTC1 CSNK1D 0 0 92 189 1 1
CRTC1 EP300 270 0 260 542 1 2
CRTC1 ADCY5 0 0 63 150 1 1
CRTC1 MARK3 0 0 0 331 1 1
CRTC1 CDK5 0 0 124 164 1 2
CRTC1 ARHGAP21 0 0 97 161 1 1
CRTC1 MLLT10 0 0 327 327 1 1
CRTC1 CRY2 0 0 82 152 1 1
CRTC1 DBN1 0 0 125 183 1 1
CRTC1 CNN2 0 0 0 189 1 1
CRTC1 CHRAC1 0 0 0 193 1 1
CRTC1 CACNG7 0 0 134 188 1 1
CRTC1 NEK10 0 0 120 255 1 1
CRTC1 YWHAG 130 0 0 234 1 1
CRTC1 MAP3K9 0 0 70 178 1 1
CRTC1 SIRT6 0 0 183 183 1 2
CRTC1 FBXL20 0 0 91 303 1 1
CRTC1 NEFL 0 0 67 155 1 1
CRTC1 SPINK7 0 0 134 369 1 1
CRTC1 KMT2B 0 0 0 207 1 1
CRTC1 NCKAP5 0 0 124 524 1 1
CRTC1 HES7 0 0 74 578 1 1
CRTC1 TMEM18 0 0 290 290 1 1
CRTC1 PDAP1 0 0 139 229 1 1
CRTC1 EREG 0 0 92 153 1 1
CRTC1 COL21A1 0 0 91 466 1 1
CRTC1 MAGI3 0 0 96 162 1 1
CRTC1 LBX1 0 0 0 325 1 1
CRTC1 MOCS1 0 0 48 207 1 1
CRTC1 VR1 0 0 155 154 1 1
CRTC1 CHD5 0 0 0 161 1 1
CRTC1 SEC14L3 0 0 154 153 1 1
CRTC1 MAP1S 0 0 96 198 1 2
CRTC1 EXD3 0 0 122 228 1 1
CRTC1 UTS2R 0 0 0 175 1 1
CRTC1 KRTDAP 0 0 113 248 1 1
CRTC1 CCDC134 0 0 181 262 1 1
CRTC1 CBFA2T3 0 0 66 153 1 1
CRTC1 REEP1 0 0 0 416 1 1
CRTC1 FOXP1 0 0 381 391 1 1
CRTC1 MYCBP 0 0 272 272 1 1
CRTC1 USP36 0 0 84 180 1 1
CRTC1 PDE1C 0 0 81 331 1 1
CRTC1 PRSS8 0 0 84 150 1 1
CRTC1 POMC 0 0 152 167 1 1
CRTC1 FNBP1 0 0 297 297 1 1
CRTC1 PPM1L 0 0 120 374 1 1
CRTC1 DOCK11 0 0 0 200 1 1
CRTC1 NRXN2 0 0 81 190 1 1
CRTC1 SMARCA5 0 0 62 271 1 1
CRTC1 RAB8B 0 0 75 172 1 2
CRTC1 GEMIN8 0 0 53 211 1 1
CRTC1 RPLP1 0 0 0 165 1 1
CRTC1 PCBP2 0 0 0 213 1 1
CRTC1 GPHN 0 0 297 297 1 1
CRTC1 CEP250 0 0 0 214 1 1
CRTC1 RPTOR 0 0 108 196 1 2
CRTC1 TUBD1 0 0 112 178 1 1
CRTC1 TRA2B 0 0 243 242 1 1
CRTC1 ATP1B1 0 0 167 273 1 1
CRTC1 MYC 0 0 141 159 1 2
CRTC1 NR0B2 0 0 370 370 1 1
CRTC1 ATP1B2 0 0 141 182 1 1
CRTC1 CLOCK 0 0 90 302 1 2
CRTC1 GRB14 0 0 164 183 1 1
CRTC1 DDX49 0 0 122 485 1 1
CRTC1 PPARGC1A 0 900 321 929 1 2
CRTC1 PCK1 0 0 218 235 1 1
CRTC1 G6PC 0 0 284 298 1 1
CRTC1 VASN 0 0 0 189 1 1
CRTC1 OBSCN 0 0 60 152 1 1
CRTC1 PPP3CB 0 0 0 152 1 1
CRTC1 TBX5 0 0 240 239 1 1
CRTC1 SBNO2 0 0 62 156 1 1
CRTC1 CETN3 0 0 67 321 1 1
CRTC1 CERS1 0 0 150 182 1 1
CRTC1 PIK3CA 0 0 160 180 1 2
CRTC1 CASC5 0 0 359 359 1 1
CRTC1 NR4A3 0 0 193 207 1 1
CRTC1 JRKL 0 0 202 321 1 1
CRTC1 ALOX12B 0 0 76 187 1 1
CRTC1 PPP3CC 0 0 49 159 1 1
CRTC1 CEP83 0 0 112 187 1 1
CRTC1 HDAC5 0 0 63 153 1 1
CRTC1 DUSP4 0 0 90 455 1 1
CRTC1 TCL1B 0 0 398 398 1 1
CRTC1 ANKRD7 0 0 174 173 1 1
CRTC1 SHANK1 0 0 66 160 1 1
CRTC1 NEGR1 0 0 81 249 1 1
CRTC1 PAPPA 0 0 50 151 1 1
CRTC1 LMTK3 0 0 124 268 1 1
CRTC1 AKT2 0 0 389 468 1 2
CRTC1 STK11 0 0 386 433 1 2
CRTC1 ANKS1B 0 0 286 368 1 1
CRTC1 AREG 0 0 324 323 1 1
CRTC1 PCNT 0 0 45 209 1 1
CRTC1 TP53 0 0 234 234 1 2
CRTC1 ZNF222 0 0 235 235 1 1
CRTC1 MIF4GD 0 0 150 203 1 1
CRTC1 MARK1 0 0 0 254 1 1
CRTC1 RPS28 0 0 0 152 1 1
CRTC1 EGFR 0 0 321 321 1 2
CRTC1 HTT 0 0 150 203 1 2
CRTC1 NCOR2 0 0 70 180 1 1
CRTC1 RAF1 0 0 413 423 1 2
CRTC1 FAM135B 0 0 123 195 1 1
CRTC1 SLC9A3R2 0 0 0 167 1 1
CRTC1 RALGAPA1 0 0 45 157 1 1
CRTC1 ZNF608 0 0 112 305 1 1
CRTC1 RNF10 0 0 164 163 1 1
CRTC1 XXYLT1 0 0 161 304 1 1
CRTC1 CDC42BPG 0 0 150 347 1 1
CRTC1 GLI4 0 0 0 151 1 1
CRTC1 JAK2 0 0 95 166 1 2
CRTC1 AFF1 0 0 305 305 1 1
CRTC1 BRD4 0 0 143 162 1 2
CRTC1 CAMKK2 0 0 134 166 1 2
CRTC1 MYBL1 0 0 241 240 1 1
CRTC1 MAML2 0 0 920 920 1 1
CRTC1 NR4A1 0 0 241 240 1 2
CRTC1 BAZ2A 0 0 0 269 1 1
CRTC1 VGF 0 0 74 175 1 1
CRTC1 REEP2 0 0 0 269 1 1
CRTC1 KRT5 0 0 145 151 1 1
CRTC1 RAB8A 0 0 0 248 1 2
CRTC1 FBXW12 0 0 167 167 1 1
CRTC1 ETNK1 0 0 0 295 1 1
CRTC1 EZH2 0 0 108 197 1 2
CRTC1 SEC16B 0 0 261 284 1 2
CRTC1 SIRT5 0 0 185 199 1 1
CRTC1 ASTE1 0 0 156 155 1 1
CRTC1 EDEM3 0 0 92 300 1 1
CRTC1 TRIM66 0 0 150 199 1 1
CRTC1 GOLT1A 0 0 49 195 1 1
CRTC1 CYHR1 0 0 53 419 1 1
CRTC1 ZMAT5 0 0 204 425 1 1
CRTC1 APP 0 0 155 176 1 2
CRTC1 SHROOM3 0 0 0 222 1 1
CRTC1 EGR1 0 0 181 187 1 2
CRTC1 TRPV1 0 0 155 154 1 2
CRTC1 WWC2 0 0 0 188 1 1
CRTC1 HCN4 0 0 0 266 1 1
CRTC1 KLC3 0 0 0 153 1 1
CRTC1 MARK4 0 0 74 278 1 1
CRTC1 NOTCH1 0 0 432 432 1 2
CRTC1 ZNF526 0 0 259 460 1 1
CRTC1 ARHGAP33 0 0 0 151 1 1
CRTC1 HCN2 0 0 0 822 1 1
CRTC1 MTOR 0 0 150 203 1 2
CRTC1 TBR1 0 0 306 306 1 1
CRTC1 MYLK2 0 0 82 152 1 1
CRTC1 KPNA1 0 0 359 359 1 1
CRTC1 BCAM 0 0 0 330 1 1
CRTC1 SEPT6 0 0 292 292 1 1
CRTC1 NUDCD1 0 0 148 332 1 1
CRTC1 GNA13 0 0 0 205 1 1
CRTC1 NPAS2 0 0 45 165 1 1
CRTC1 TNFRSF19 0 0 57 263 1 1
CRTC1 CHD1L 0 0 0 189 1 1
CRTC1 LYPD3 0 0 204 205 1 1
CRTC1 CPNE3 0 0 107 162 1 1
CRTC1 AQP8 0 0 60 159 1 1
CRTC1 NOTCH4 0 0 308 307 1 1
CRTC1 ATP1A3 0 0 89 180 1 1
CRTC1 CREBBP 270 0 462 667 1 1
CRTC1 WDR3 0 0 135 227 1 1
CRTC1 RAPGEF3 0 0 128 189 1 1
CRTC1 ZNFX1 0 0 105 242 1 1
CRTC1 CREB1 433 800 979 998 1 2
CRTC1 CLCF1 0 0 73 242 1 1
CRTC1 RAB40B 0 0 123 204 1 1
CRTC1 FTO 0 0 193 193 1 2
CRTC1 FBXO32 0 0 297 297 1 2
CRTC1 VNN3 0 0 127 364 1 1
CRTC1 SIRT2 0 0 181 260 1 2
CRTC1 GRID2IP 0 0 0 193 1 1
CRTC1 DPAGT1 0 0 57 151 1 1
CRTC1 USP43 0 0 127 220 1 1
CRTC1 COL11A2 0 0 66 167 1 1
CRTC1 TMEM203 0 0 264 264 1 1
CRTC1 SH2D1B 0 0 44 183 1 1
CRTC1 KISS1 0 0 398 398 1 1
CRTC1 ZDHHC23 0 0 51 226 1 1
CRTC1 AFF3 0 0 295 295 1 1
CRTC1 OTOGL 0 0 142 230 1 1
CRTC1 PHKA2 0 0 74 524 1 1
CRTC1 WWC1 0 0 0 240 1 1
CRTC1 GAPDH 0 0 194 195 1 2
CRTC1 KHDRBS2 0 0 136 177 1 1
CRTC1 ZNF579 0 0 0 215 1 1
CRTC1 ABL1 0 0 108 157 1 1
CRTC1 PDZD11 0 0 0 345 1 1
CRTC1 FBXL19 0 0 102 175 1 1
CRTC1 ZNF461 0 0 231 348 1 1
CRTC1 TCEB3B 0 0 232 231 1 1
CRTC1 GRIN2B 0 0 220 242 1 1
CRTC1 MLH1 0 0 61 190 1 1
CRTC1 PDYN 0 0 306 323 1 1
CRTC1 TFE3 0 0 140 169 1 2
CRTC1 SMYD2 0 0 63 301 1 1
CRTC1 CAMK4 0 0 203 244 1 1
CRTC1 ASPSCR1 0 0 150 212 1 1
CRTC1 FOXO1 0 0 194 194 1 2
CRTC1 FOS 0 900 294 926 1 2
CRTC1 CRNN 0 0 92 158 1 1
CRTC1 YWHAZ 305 0 0 433 1 1
CRTC1 BSX 0 0 282 282 1 1
CRTC1 SPACA5 0 0 96 253 1 1
CRTC1 GAB1 0 0 70 156 1 1
CRTC1 RXRA 0 0 95 172 1 1
CRTC1 DDX31 0 0 0 208 1 1
CRTC1 YPEL3 0 0 113 163 1 1
CRTC1 SUCLG2 0 0 47 540 1 1
CRTC1 NPAS4 0 0 210 242 1 1
CRTC1 SIPA1L1 0 0 116 199 1 1
CRTC1 YWHAH 234 0 0 325 1 1
CRTC1 PROKR2 0 0 67 160 1 1
CRTC1 JAKMIP1 0 0 112 266 1 1
CRTC1 CDH23 0 0 96 256 1 1
CRTC1 HDAC1 0 0 108 172 1 2
CRTC1 SST 0 0 122 156 1 1
CRTC1 CDKN2A 0 0 184 183 1 2
CRTC1 SIK1 0 0 700 850 1 1
CRTC1 PDE1A 0 0 0 223 1 1
CRTC1 KRT7 0 0 181 201 1 1
CRTC1 MTCH2 0 0 73 325 1 1
CRTC1 TBC1D1 0 0 88 172 1 1
CRTC1 ADAMTSL1 0 0 0 260 1 1
CRTC1 MCHR2 0 0 336 336 1 1
CRTC1 BAIAP2 0 0 60 150 1 1
CRTC1 FAM131B 0 0 130 181 1 1
CRTC1 TET1 0 0 188 188 1 1
CRTC1 FSIP1 0 0 134 321 1 1
CRTC1 HELLS 0 0 0 189 1 1
CRTC1 TIMELESS 0 0 76 170 1 1
CRTC1 SMARCA1 0 0 0 254 1 1
CRTC1 BZW1 0 0 113 165 1 1
CRTC1 LMO7 0 0 95 303 1 1
CRTC1 MLLT3 0 0 306 306 1 1
CRTC1 NFIB 0 0 520 541 1 1
CRTC1 SLC6A14 0 0 81 222 1 1
CRTC1 GPRC5C 0 0 97 580 1 1
CRTC1 TPSG1 0 0 0 325 1 1
CRTC1 NTRK3 0 0 369 380 1 1
CRTC1 MLLT6 0 0 350 368 1 1
CRTC1 SCEL 0 0 181 276 1 1
CRTC1 FBXL2 0 0 0 214 1 1
CRTC1 KAT5 0 0 183 183 1 1
CRTC1 FKBP2 0 0 0 189 1 1
CRTC1 RCOR2 0 0 0 156 1 1
CRTC1 MARK2 0 0 146 350 1 1
CRTC1 SARNP 0 0 359 359 1 1
CRTC1 CAPN7 0 0 112 248 1 1
CRTC1 CLPB 0 0 66 312 1 1
CRTC1 RNF157 0 0 46 310 1 1
CRTC1 RHOT2 0 0 81 157 1 1
CRTC1 LEP 0 0 261 274 1 1
CRTC1 KIT 0 0 131 170 1 2
CRTC1 SH3GL1 0 0 268 268 1 1
CRTC1 CCNA1 0 0 75 173 1 1
CRTC1 ZNF263 0 0 95 170 1 1
CRTC1 TAF4B 0 0 0 206 1 1
CRTC1 SIK3 0 0 405 702 1 1
CRTC1 SOX10 0 0 158 184 1 1
CRTC1 OGT 0 0 540 540 1 2
CRTC1 SLC35E4 0 0 0 181 1 1
CRTC1 BAZ2B 0 0 0 269 1 1
CRTC1 AGRP 0 0 134 161 1 1
CRTC1 RAP1GAP 0 0 412 433 1 1
CRTC1 EZR 0 0 0 190 1 1
CRTC1 RBPJ 0 0 134 171 1 1
CRTC1 PPARGC1B 0 0 296 296 1 1
CRTC1 RXRG 0 0 161 167 1 1
CRTC1 POF1B 0 0 123 277 1 1
CRTC1 DLG4 0 0 143 241 1 2
CRTC1 UBC 0 0 0 177 1 2
CRTC1 DUSP14 0 0 0 207 1 1
CRTC1 DMWD 0 0 134 167 1 1
CRTC1 TXNL4B 0 0 103 251 1 1
CRTC1 HTR3C 0 0 167 167 1 1
CRTC1 CTHRC1 0 0 96 234 1 1
CRTC1 BARX1 0 0 595 595 1 1
CRTC1 PMPCB 0 0 0 179 1 1
CRTC1 ZFPM1 0 0 0 155 1 1
CRTC1 TET2 0 0 94 150 1 2
CRTC1 LRFN2 0 0 0 275 1 1
CRTC1 PCBP1 0 0 0 161 1 1
CRTC1 AKT3 0 0 0 165 1 2
CRTC1 SPRED2 0 0 414 414 1 2
CRTC1 NONO 0 0 448 524 1 1
CRTC1 RABL3 0 0 172 223 1 1
CRTC1 FAAH2 0 0 167 598 1 1
CRTC1 CAMK2A 0 0 103 197 1 2
CRTC1 ULK1 0 0 81 162 1 2
CRTC1 HOMER1 0 0 151 150 1 1
CRTC1 ACTL6B 0 0 72 159 1 1
CRTC1 PCBP3 0 0 134 603 1 1
CRTC1 RGS2 0 0 181 208 1 1
CRTC1 SIRT1 0 0 265 281 1 2
CRTC1 PDZRN3 0 0 124 217 1 1
CRTC1 TPPP 0 0 90 190 1 1
CRTC1 SMEK1 0 0 135 169 1 1
CRTC1 UFM1 0 0 81 453 1 1
CRTC1 MLLT1 0 0 270 296 1 1
CRTC1 PRKD1 0 0 234 234 1 1
CRTC1 CAMK1 0 0 113 168 1 1
CRTC1 CRH 0 0 447 447 1 1
CRTC1 GRIN1 0 0 0 228 1 1
CRTC1 EPB41L4A 0 0 125 212 1 1
CRTC1 PRR18 0 0 253 291 1 1
CRTC1 SYP 0 0 123 165 1 1
CRTC1 NR4A2 0 0 359 359 1 1
CRTC1 AEN 0 0 111 247 1 1
CRTC1 FBXO18 0 0 94 164 1 1
CRTC1 DDX51 0 0 146 368 1 1
CRTC1 FBXO41 0 0 0 188 1 1
CRTC1 HOXA3 0 0 0 232 1 1
CRTC1 BDNF 0 0 488 488 1 2
CRTC1 UQCRC1 0 0 113 171 1 1
CRTC1 NFYC 0 0 66 330 1 1
CRTC1 PLAG1 0 0 518 518 1 1
CRTC1 C15orf54 0 0 183 183 1 1
CRTC1 PHKA1 0 0 0 219 1 1
CRTC1 ABCA2 0 0 0 156 1 1
CRTC1 BAHD1 0 0 129 251 1 1
CRTC1 PEBP1 0 0 309 309 1 1
CRTC1 SHROOM2 0 0 0 323 1 1
CRTC1 KMT2A 0 0 116 344 1 1
CRTC1 PTCH1 0 0 93 183 1 1
CRTC1 ACER2 0 0 103 166 1 1
CRTC1 GCG 0 0 185 197 1 1
CRTC1 ARNTL 0 0 180 325 1 1
CRTC1 WDFY3 0 0 0 189 1 2
CRTC1 NOL8 0 0 54 153 1 1
CRTC1 PROK2 0 0 95 192 1 1
CRTC1 NCOR1 0 0 160 219 1 1
CRTC1 PER1 0 900 0 913 1 1
CRTC1 ETV6 0 0 427 431 1 1
CRTC1 CCDC94 0 0 73 311 1 1
CRTC1 RFWD2 0 0 96 168 1 1
CRTC1 CRLF1 0 0 107 309 1 1
CRTC1 YWHAQ 242 0 46 356 1 1
CRTC1 KAT2B 0 0 113 273 1 1
CRTC1 HDAC7 0 0 108 208 1 1
CRTC1 PLEKHG2 0 0 170 169 1 1
CRTC1 MEIS1 270 0 0 280 1 1
CRTC1 AP1G2 0 0 52 152 1 1
CRTC1 SPTBN5 0 0 57 263 1 1
CRTC1 REEP3 0 0 0 245 1 1
CRTC1 PSPC1 0 0 310 347 1 1
CRTC1 CELF3 0 0 0 164 1 1
CRTC1 ADCY2 0 0 95 170 1 1
CRTC1 REEP4 0 0 0 336 1 1
CRTC1 DLGAP3 0 0 97 199 1 1
CRTC1 PAGE5 0 0 165 165 1 1
CRTC1 NPFFR2 0 0 93 252 1 1
CRTC1 UBB 0 0 0 204 1 1
CRTC1 POU5F1 0 0 129 180 1 2
CRTC1 FBXL4 0 0 0 180 1 1
CRTC1 NUTM1 0 0 264 264 1 1
CRTC1 GRIA1 0 0 125 199 1 1
CRTC1 SMG7 0 0 74 326 1 1
CRTC1 SLC9A3R1 0 0 56 155 1 1
CRTC1 CCT6A 0 0 87 152 1 1
CRTC1 MITF 0 0 166 188 1 2
CRTC1 MOS 0 0 173 187 1 1
CRTC1 JAK1 0 0 46 166 1 2
CRTC1 CNN3 0 0 0 189 1 1
CRTC1 ADAMTSL3 0 0 95 301 1 1
CRTC1 ATF6B 0 0 0 176 1 1
CRTC1 YY1 0 0 67 160 1 1
CRTC1 HSD17B12 0 0 74 243 1 1
CRTC1 CNN1 0 0 0 189 1 1
CRTC1 PPAN-P2RY11 0 0 0 190 1 1
CRTC1 IGSF5 0 0 0 187 1 1
CRTC1 PARP10 0 0 0 198 1 1
CRTC1 CMTM8 0 0 123 219 1 1
CRTC1 AES 0 0 107 162 1 1
CRTC1 TSC2 0 0 112 258 1 2
CRTC1 CUEDC2 0 0 123 198 1 1
CRTC1 EPHB3 0 0 48 168 1 1
CRTC1 NAA16 0 0 170 605 1 1
CRTC1 CDC37L1 0 0 123 150 1 1
CRTC1 YWHAB 130 0 61 275 1 1
CRTC1 SLC2A4 0 0 157 156 1 1
CRTC1 SPRED1 0 0 649 649 1 1
CRTC1 FOXO3 0 0 161 213 1 2
CRTC1 NEXN 0 0 57 373 1 1
CRTC1 CRY1 0 0 141 226 1 1
CRTC1 EWSR1 0 0 459 459 1 1
CRTC1 GAD1 0 0 90 155 1 1
CRTC1 THOC5 0 0 96 161 1 1
CRTC1 JMJD7-PLA2G4B 0 0 123 155 1 1
CRTC1 TAF4 0 0 232 364 1 1
CRTC1 NSMF 0 0 112 187 1 1
CRTC1 PDE1B 0 0 0 161 1 1
CRTC1 CASKIN1 0 0 0 311 1 1
CRTC1 TXNDC9 0 0 411 416 1 1
CRTC1 SLC5A3 0 0 90 182 1 1
CRTC1 TCL1A 0 0 356 356 1 1
CRTC1 PRUNE 0 0 123 274 1 1
CRTC1 GMPS 0 0 388 388 1 1
CRTC1 GPRC5B 0 0 84 510 1 1
CRTC1 ABCA12 0 0 68 210 1 1
CRTC1 DRD4 0 0 0 677 1 1
CRTC1 KCNAB1 0 0 0 167 1 1
CRTC1 FAAH 0 0 0 237 1 1
CRTC1 PPP3CA 0 0 134 251 1 1
CRTC1 SIRT4 0 0 163 163 1 1
CRTC1 HMGA2 0 0 292 292 1 1
CRTC1 ERBB2 0 0 210 210 1 2
CRTC1 LETM2 0 0 54 259 1 1
CRTC1 FOXF1 0 0 458 464 1 1
CRTC1 CREM 0 0 297 512 1 1
CRTC1 MAP3K1 270 0 95 311 1 1
CRTC1 ARHGEF12 0 0 297 297 1 1
CRTC1 ZNF574 0 0 0 246 1 1
CRTC1 ATF1 0 0 155 331 1 1
CRTC1 PRDM16 0 0 295 295 1 1
CRTC1 REEP6 0 0 0 154 1 1
CRTC1 SIK1B 0 0 0 520 1 1
CRTC1 AKT1 0 0 189 294 1 2
CRTC1 PCBP4 0 0 0 192 1 1
CRTC1 ATF6 0 0 90 218 1 2
CRTC1 GDF7 0 0 395 394 1 1
CRTC1 LETM1 0 0 77 479 1 1
CRTC1 KCNAB2 0 0 150 349 1 1
CRTC1 MZF1 0 0 108 208 1 1
CRTC1 NTRK2 0 0 145 190 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0008140 Molecular Function cAMP response element binding protein binding enables IBA
GO:0008140 Molecular Function cAMP response element binding protein binding enables IDA
GO:0005515 Molecular Function protein binding enables IPI
GO:0097009 Biological Process energy homeostasis involved_in IEA
GO:0043153 Biological Process entrainment of circadian clock by photoperiod involved_in ISS
GO:0007613 Biological Process memory involved_in IEA
GO:1902631 Biological Process negative regulation of membrane hyperpolarization involved_in IEA
GO:0032793 Biological Process positive regulation of CREB transcription factor activity involved_in IBA
GO:0032793 Biological Process positive regulation of CREB transcription factor activity involved_in ISS
GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II involved_in IBA
GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II involved_in IDA
GO:0051289 Biological Process protein homotetramerization involved_in IEA
GO:0048511 Biological Process rhythmic process involved_in IEA
GO:0005737 Cellular Component cytoplasm is_active_in IBA
GO:0005829 Cellular Component cytosol located_in IDA
GO:0016604 Cellular Component nuclear body located_in IDA
GO:0005654 Cellular Component nucleoplasm located_in IDA
GO:0005634 Cellular Component nucleus is_active_in IBA
GO:0005634 Cellular Component nucleus located_in IDA
GO:0005886 Cellular Component plasma membrane located_in IDA
Pathways
Name DB ID
Mitochondrial biogenesis Reactome R-HSA-1592230
Organelle biogenesis and maintenance Reactome R-HSA-1852241
Transcriptional activation of mitochondrial biogenesis Reactome R-HSA-2151201
Cellular responses to stress Reactome R-HSA-2262752
Circadian Clock Reactome R-HSA-400253
Cellular responses to stimuli Reactome R-HSA-8953897
Heme signaling Reactome R-HSA-9707616
Endoderm differentiation (WP2853) WikiPathways WP2853_r116557
Mesodermal commitment pathway (WP2857) WikiPathways WP2857_r118395
Brain-derived neurotrophic factor (BDNF) signaling pathway (WP2380) WikiPathways WP2380_r120727
Circadian rhythm genes (WP3594) WikiPathways WP3594_r117682
Transcripts
Accession Version MolecularType Name NCBI Comments
NM_001098482 2 mRNA transcript variant 3 NC_000019 Reference
NM_015321 3 mRNA transcript variant 1 NC_000019 Reference