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SIRT3

sirtuin 3
General Information
Name sirtuin 3
Alias
  • NAD-dependent protein deacetylase sirtuin-3, mitochondrial
  • NAD-dependent deacetylase sirtuin-3, mitochondrial
  • SIR2-like protein 3
  • mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase
  • regulatory protein SIR2 homolog 3
  • silent mating type information regulation 2, S.cerevisiae, homolog 3
  • sir2-like 3
  • sirtuin type 3
Gene_family Sirtuins
organism Homo sapiens
entrez_id 23410
location 11p15.5
transcript_count 38
exon_count 10
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez SIRT3 encodes a member of the sirtuin family of class III histone deacetylases, homologs to the yeast Sir2 protein. The encoded protein is found exclusively in mitochondria, where it can eliminate reactive oxygen species, inhibit apoptosis, and prevent the formation of cancer cells. SIRT3 has far-reaching effects on nuclear gene expression, cancer, cardiovascular disease, neuroprotection, aging, and metabolic control. [provided by RefSeq, May 2019]
    Stringdb NAD-dependent protein deacetylase sirtuin-3, mitochondrial; NAD-dependent protein deacetylase. Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues. Known targets include ACSS1, IDH, GDH, SOD2, PDHA1, LCAD, SDHA and the ATP synthase subunit ATP5O. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels; Sirtuins
    nextProt NAD-dependent protein deacetylase (PubMed:12186850, PubMed:12374852, PubMed:16788062, PubMed:18680753, PubMed:18794531, PubMed:23283301, PubMed:24121500, PubMed:24252090, PubMed:19535340). Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues (PubMed:12186850, PubMed:12374852, PubMed:16788062, PubMed:18680753, PubMed:18794531, PubMed:23283301, PubMed:24121500, PubMed:24252090). Known targets include ACSS1, IDH, GDH, SOD2, PDHA1, LCAD, SDHA and the ATP synthase subunit ATP5PO (PubMed:16788062, PubMed:18680753, PubMed:24121500, PubMed:24252090, PubMed:19535340). Contributes to the regulation of the cellular energy metabolism (PubMed:24252090). Important for regulating tissue-specific ATP levels (PubMed:18794531). In response to metabolic stress, deacetylates transcription factor FOXO3 and recruits FOXO3 and mitochondrial RNA polymerase POLRMT to mtDNA to promote mtDNA transcription (PubMed:23283301). Acts as a regulator of ceramide metabolism by mediating deacetylation of ceramide synthases CERS1, CERS2 and CERS6, thereby increasing their activity and promoting mitochondrial ceramide accumulation (By similarity).
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
SIRT3 BioGRID GLDC GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity
SIRT3 BioGRID ECHS1 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
SIRT3 BioGRID TRIM67 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID IDH2 GeneID BioGRID Affinity Capture-Western
SIRT3 BioGRID MCL1 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
SIRT3 BioGRID LATS1 GeneID BioGRID Affinity Capture-Western
SIRT3 BioGRID C1QTNF8 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID NDUFS7 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID LSM14B GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID TRIM43 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID MALSU1 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID AHNAK2 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID MARS2 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID REG4 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID MICAL1 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID ELP3 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID MRPS18C GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID MRPL42 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID MRPS18B GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID NIPSNAP3A GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID SSBP3 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID SNX3 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID UQCRFS1 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID SRC GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID SDHA GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID NDUFS6 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID HSPD1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Proximity Label-MS; Reconstituted Complex
SIRT3 BioGRID CNP GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID ASS1 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID ANXA13 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID PDHA1 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Proximity Label-MS
SIRT3 BioGRID ORF8b GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID HSCB GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID HSDL2 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
SIRT3 BioGRID ACAD9 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
SIRT3 BioGRID ETHE1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
SIRT3 BioGRID RUVBL1 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID H4C1 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID PYCR1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
SIRT3 BioGRID PDK2 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
SIRT3 BioGRID PDHB GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID HSD17B10 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID GLUD1 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID CS GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
SIRT3 BioGRID ATP5F1A GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
SIRT3 BioGRID ACADVL GeneID BioGRID Affinity Capture-MS; Biochemical Activity
SIRT3 BioGRID H3C1 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
SIRT3 BioGRID TP53BP1 GeneID BioGRID Co-localization
SIRT3 BioGRID PDK1 GeneID BioGRID Proximity Label-MS
SIRT3 BioGRID ESR2 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID ALDH2 GeneID BioGRID Biochemical Activity; Reconstituted Complex
SIRT3 BioGRID PDP1 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
SIRT3 BioGRID YBEY GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID MTG2 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID DMC1 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID SDHB GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID NIT1 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID NDUFA10 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID FECH GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID CA5A GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID ATP5F1D GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID OXLD1 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID METAP1D GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID TMEM25 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID MDM2 GeneID BioGRID Biochemical Activity
SIRT3 BioGRID ARHGEF26 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID SIRT5 GeneID BioGRID Affinity Capture-Western; Negative Genetic
SIRT3 BioGRID SKP2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
SIRT3 BioGRID CMYA5 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID PGAP1 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID RIF1 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID NCAPD2 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID HERC2 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID TTF2 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID UQCRH GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID UGDH GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID HSP90B1 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID SNTB1 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID SBF1 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID HSPA9 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID HSPA5 GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID HSPA4 GeneID BioGRID Affinity Capture-Western
SIRT3 BioGRID HSPA1L GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID GRN GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID ATP5F1B GeneID BioGRID Affinity Capture-MS
SIRT3 BioGRID SIRT4 GeneID BioGRID Affinity Capture-Western
SIRT3 BioGRID tat GeneID BioGRID Biochemical Activity
SIRT3 BioGRID XRCC6 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
SIRT3 BioGRID FOXO3 GeneID BioGRID Affinity Capture-Western
SIRT3 Protein DNM1L GeneID HPRD
SIRT3 Protein PEX5 GeneID HPRD
SIRT3 BioGRID PEX5 GeneID BioGRID Two-hybrid
StringDB
A B experiments database textmining combined score hadb nhadb
SIRT3 C1QBP 0 0 0 218 1 1
SIRT3 GPX6 0 0 0 198 1 1
SIRT3 CRTC1 0 0 194 357 1 2
SIRT3 COX7B2 0 0 0 210 1 1
SIRT3 SIN3B 0 0 95 159 1 1
SIRT3 MPHOSPH8 0 0 59 267 1 1
SIRT3 CRAT 0 0 310 330 1 1
SIRT3 TMEM256 0 0 0 323 1 1
SIRT3 FOXO3 270 900 986 999 1 2
SIRT3 VDAC3 0 0 233 242 1 1
SIRT3 SLC2A4 0 0 459 475 1 1
SIRT3 APOE 0 0 391 390 1 2
SIRT3 POLB 0 0 213 280 1 1
SIRT3 PAPD7 0 0 0 161 1 1
SIRT3 BGLAP 0 0 454 454 1 1
SIRT3 CRY1 0 0 339 404 1 1
SIRT3 RTN3 0 0 0 160 1 1
SIRT3 TAF4 0 0 117 181 1 1
SIRT3 COMT 0 0 140 233 1 1
SIRT3 HNF4A 0 0 244 335 1 1
SIRT3 LYPLA2 0 0 0 211 1 1
SIRT3 TXNDC9 0 0 167 167 1 1
SIRT3 DNAJB1 0 0 158 182 1 2
SIRT3 ATG3 0 0 205 216 1 2
SIRT3 PARP9 0 0 261 292 1 1
SIRT3 JDP2 0 0 0 440 1 1
SIRT3 CDKN3 0 0 193 289 1 1
SIRT3 KDR 0 0 160 159 1 2
SIRT3 PRMT5 0 0 235 262 1 1
SIRT3 HIST1H2BJ 0 0 0 170 1 1
SIRT3 AGTR2 0 0 171 171 1 1
SIRT3 YY1 0 0 282 294 1 1
SIRT3 MARCH5 0 0 150 203 1 1
SIRT3 PNP 0 900 150 920 1 1
SIRT3 ASPN 0 0 160 174 1 1
SIRT3 H2AFJ 0 0 0 151 1 1
SIRT3 FOXP3 0 0 204 307 1 2
SIRT3 MDH2 0 0 323 392 1 1
SIRT3 HIST1H4D 0 0 560 643 1 1
SIRT3 PRKCD 0 0 193 193 1 2
SIRT3 PGP 0 0 0 213 1 1
SIRT3 GSTZ1 0 0 57 152 1 1
SIRT3 DIO2 0 0 194 194 1 1
SIRT3 PITPNB 0 0 0 298 1 1
SIRT3 TEP1 0 0 0 160 1 1
SIRT3 FOXD2 0 0 61 183 1 1
SIRT3 PARP10 0 0 310 309 1 1
SIRT3 OXCT1 0 0 204 204 1 1
SIRT3 TGFB1 0 0 125 179 1 2
SIRT3 VDAC1 0 0 517 539 1 2
SIRT3 DDB1 0 0 92 151 1 1
SIRT3 RAB7B 0 0 155 154 1 1
SIRT3 SBF2 0 0 0 312 1 1
SIRT3 GLUL 0 0 173 173 1 1
SIRT3 UQCRFS1 0 0 217 385 1 1
SIRT3 VCAM1 0 0 240 239 1 1
SIRT3 HSPH1 0 0 0 164 1 1
SIRT3 ISCU 0 0 151 205 1 1
SIRT3 CA9 0 0 123 156 1 1
SIRT3 SUMO1 0 0 141 163 1 1
SIRT3 CLPP 0 0 241 283 1 1
SIRT3 PARP4 0 0 218 239 1 1
SIRT3 HIST1H4C 0 0 560 643 1 1
SIRT3 PPP1R9B 0 0 0 171 1 1
SIRT3 CPT1A 0 0 321 325 1 1
SIRT3 PSMD5 0 0 115 175 1 1
SIRT3 KMT2D 0 0 137 249 1 1
SIRT3 PARL 0 0 212 229 1 1
SIRT3 DROSHA 0 0 145 208 1 1
SIRT3 SDHD 0 0 212 408 1 1
SIRT3 NOX4 0 0 400 413 1 2
SIRT3 ING1 0 0 95 579 1 1
SIRT3 NADK 0 0 293 419 1 1
SIRT3 DUOX1 0 0 203 203 1 1
SIRT3 SSH2 0 0 0 156 1 1
SIRT3 TNKS2 0 0 263 317 1 1
SIRT3 ACACB 0 0 210 224 1 1
SIRT3 MACROD2 0 0 325 489 1 1
SIRT3 PHF20 0 0 0 166 1 1
SIRT3 EIF4EBP1 0 0 268 277 1 2
SIRT3 EP400NL 0 0 0 183 1 1
SIRT3 FOXO4 0 0 419 508 1 1
SIRT3 DLD 0 0 167 192 1 2
SIRT3 GJA1 0 0 170 169 1 1
SIRT3 NDUFB3 0 0 0 274 1 1
SIRT3 FOXH1 0 0 0 166 1 1
SIRT3 PINK1 0 0 508 550 1 2
SIRT3 BCL6 0 0 212 243 1 1
SIRT3 PDE5A 0 0 146 195 1 1
SIRT3 SSRP1 0 0 88 192 1 1
SIRT3 PHGDH 0 0 244 250 1 1
SIRT3 MTG2 483 0 0 483 1 1
SIRT3 GPT 0 0 246 245 1 1
SIRT3 TH 0 0 193 221 1 2
SIRT3 TMED5 0 0 0 171 1 1
SIRT3 DENR 0 0 261 305 1 1
SIRT3 FOXF1 0 0 0 166 1 1
SIRT3 LETM2 0 0 56 286 1 1
SIRT3 FOXJ1 0 0 0 166 1 1
SIRT3 DHODH 0 0 155 184 1 1
SIRT3 CD34 0 0 171 171 1 2
SIRT3 NGF 0 0 193 232 1 2
SIRT3 HIST1H2BN 0 0 0 170 1 1
SIRT3 PDPR 0 0 0 201 1 1
SIRT3 GOSR1 0 0 0 183 1 1
SIRT3 FOXQ1 0 0 44 168 1 1
SIRT3 KMT2A 0 0 124 237 1 1
SIRT3 GUF1 0 0 0 163 1 1
SIRT3 FOXK2 0 0 0 166 1 1
SIRT3 RELB 0 0 202 202 1 2
SIRT3 GEN1 0 0 0 168 1 1
SIRT3 FGF2 0 0 216 216 1 2
SIRT3 BYSL 0 0 43 216 1 1
SIRT3 PPTC7 0 0 67 154 1 1
SIRT3 HIST1H4H 0 0 561 644 1 1
SIRT3 CYB5R3 0 0 171 171 1 1
SIRT3 CUL4B 0 0 67 178 1 1
SIRT3 PRDX2 0 0 137 210 1 1
SIRT3 GFOD2 0 0 0 165 1 1
SIRT3 SUV39H2 0 0 159 268 1 1
SIRT3 APOB 0 0 171 324 1 2
SIRT3 IGF1 0 0 603 603 1 2
SIRT3 HIST1H3H 0 0 48 191 1 1
SIRT3 MAPK1 0 0 122 152 1 2
SIRT3 RPS19BP1 0 0 391 390 1 1
SIRT3 GADD45A 0 0 260 273 1 1
SIRT3 PKM 0 0 377 401 1 1
SIRT3 UCP3 0 0 407 459 1 1
SIRT3 CASP2 0 0 134 152 1 1
SIRT3 DUSP26 0 0 0 156 1 1
SIRT3 HIPK3 0 0 0 197 1 1
SIRT3 BDNF 0 0 400 400 1 2
SIRT3 HSPA2 0 0 45 168 1 1
SIRT3 XDH 0 0 74 169 1 1
SIRT3 HSPA13 0 0 0 164 1 1
SIRT3 NUP210 0 0 0 160 1 1
SIRT3 SIX1 0 0 72 214 1 1
SIRT3 ABHD10 0 0 0 172 1 1
SIRT3 MFSD10 0 0 0 167 1 1
SIRT3 TIPIN 0 0 0 193 1 1
SIRT3 RAVER1 0 0 0 151 1 1
SIRT3 CBSL 0 0 164 163 1 1
SIRT3 IDH3A 0 0 113 254 1 1
SIRT3 GLS2 0 0 232 236 1 1
SIRT3 NRIP1 0 0 236 236 1 1
SIRT3 ACADM 0 0 325 376 1 1
SIRT3 MUTYH 0 0 82 204 1 1
SIRT3 FOXR1 0 0 0 166 1 1
SIRT3 NDUFA7 0 0 134 208 1 1
SIRT3 NR1D1 0 0 325 341 1 2
SIRT3 CD38 0 650 518 824 1 2
SIRT3 PITPNM2 0 0 46 195 1 1
SIRT3 GNPNAT1 0 0 67 151 1 1
SIRT3 HIST2H4B 0 0 560 643 1 1
SIRT3 RHEB 0 0 242 241 1 2
SIRT3 SMYD4 0 0 0 165 1 1
SIRT3 NADSYN1 0 900 156 931 1 1
SIRT3 LDLR 0 0 140 157 1 2
SIRT3 CYC1 0 0 60 198 1 1
SIRT3 NDUFA10 274 0 149 410 1 1
SIRT3 IDE 0 0 279 319 1 1
SIRT3 ATP5J 0 0 120 250 1 1
SIRT3 MCUR1 0 0 90 237 1 1
SIRT3 MCM10 0 0 0 241 1 1
SIRT3 ARPC4 0 0 0 188 1 1
SIRT3 SSBP1 0 0 181 224 1 1
SIRT3 ENSG00000264813 0 0 294 294 1 1
SIRT3 AOX1 0 0 151 163 1 1
SIRT3 TXN 0 0 460 471 1 1
SIRT3 ABCG5 0 0 60 189 1 1
SIRT3 FOXP4 0 0 0 166 1 1
SIRT3 NDUFA13 0 0 107 356 1 1
SIRT3 FH 0 0 361 389 1 1
SIRT3 NDUFB5 0 0 91 176 1 1
SIRT3 STYXL1 0 0 60 172 1 1
SIRT3 CHCHD4 0 0 137 182 1 1
SIRT3 PRPS2 0 0 0 151 1 1
SIRT3 HMGCR 0 0 193 271 1 1
SIRT3 HIST2H2BE 0 0 455 528 1 1
SIRT3 PRKDC 0 0 165 309 1 2
SIRT3 EIF4E 0 0 193 209 1 2
SIRT3 KAT2B 0 0 608 697 1 1
SIRT3 YWHAQ 0 0 123 254 1 1
SIRT3 CD36 0 0 166 165 1 2
SIRT3 RRM2B 0 0 82 153 1 1
SIRT3 NOS3 0 0 517 528 1 2
SIRT3 ACTA2 0 0 70 161 1 1
SIRT3 CCND1 0 0 316 315 1 2
SIRT3 PRKAA1 0 0 167 195 1 2
SIRT3 ATP5F1 0 0 150 276 1 1
SIRT3 NCF1 0 0 218 218 1 1
SIRT3 GID4 0 0 48 201 1 1
SIRT3 G6PD 0 0 294 303 1 1
SIRT3 AGRP 0 0 242 241 1 1
SIRT3 NAA40 0 0 0 353 1 1
SIRT3 BAZ2B 0 0 74 219 1 1
SIRT3 POLI 0 0 293 330 1 1
SIRT3 ENSG00000267261 0 0 0 191 1 1
SIRT3 FOXN4 0 0 0 166 1 1
SIRT3 IDH2 0 900 617 963 1 1
SIRT3 CTSD 0 0 147 191 1 2
SIRT3 TOMM70A 0 0 161 254 1 1
SIRT3 ATM 0 0 409 467 1 2
SIRT3 SHC1 0 0 125 200 1 1
SIRT3 SMAD5 0 0 67 202 1 1
SIRT3 SLC17A1 0 0 289 288 1 1
SIRT3 MRE11A 0 0 0 237 1 1
SIRT3 MT-ND4 0 0 184 305 1 1
SIRT3 GFAP 0 0 113 179 1 2
SIRT3 CHD4 0 0 117 167 1 1
SIRT3 CPT1C 0 0 275 279 1 1
SIRT3 PPARGC1B 0 0 212 313 1 1
SIRT3 NAMPT 0 900 753 979 1 2
SIRT3 KDM4D 0 0 145 158 1 1
SIRT3 RBPJ 0 0 112 192 1 1
SIRT3 EGLN2 0 0 184 201 1 1
SIRT3 ATG7 0 0 465 539 1 2
SIRT3 CMPK2 0 0 0 180 1 1
SIRT3 RECQL4 0 0 118 265 1 1
SIRT3 ACTG1 0 0 170 207 1 1
SIRT3 WIPI1 0 0 134 193 1 2
SIRT3 SRCAP 0 0 48 189 1 1
SIRT3 DNM1L 116 0 601 681 1 2
SIRT3 MYOD1 0 0 290 294 1 1
SIRT3 UBN1 0 0 0 161 1 1
SIRT3 IARS2 0 0 0 243 1 1
SIRT3 VILL 0 0 0 207 1 1
SIRT3 PRKAA2 0 0 167 194 1 2
SIRT3 H2BFM 0 0 0 170 1 1
SIRT3 ISOC1 0 0 0 264 1 1
SIRT3 VEGFA 0 0 406 406 1 2
SIRT3 KDM5C 0 0 158 225 1 1
SIRT3 HIST1H3A 270 0 48 384 1 1
SIRT3 TXN2 0 0 364 379 1 1
SIRT3 GABARAP 0 0 142 214 1 2
SIRT3 DYRK4 0 0 0 189 1 1
SIRT3 NCOA6 0 0 45 359 1 1
SIRT3 PTEN 0 0 404 476 1 2
SIRT3 NDUFA9 270 0 956 975 1 1
SIRT3 PSORS1C2 0 0 0 165 1 1
SIRT3 MAPK14 0 0 181 214 1 2
SIRT3 HIST1H4A 0 0 560 643 1 1
SIRT3 MAPK10 0 0 93 163 1 2
SIRT3 UCP1 0 0 506 542 1 2
SIRT3 SREBF1 0 0 467 486 1 1
SIRT3 ATAD2B 0 0 0 238 1 1
SIRT3 HIST1H3C 0 0 76 215 1 1
SIRT3 CLPB 0 0 57 182 1 1
SIRT3 C12orf5 0 0 260 292 1 1
SIRT3 PARP16 0 0 281 281 1 1
SIRT3 HFE 0 0 0 185 1 1
SIRT3 PHF6 0 0 0 165 1 1
SIRT3 NFKBIA 0 0 235 282 1 2
SIRT3 LEP 0 0 452 452 1 1
SIRT3 MAP3K5 0 0 235 235 1 1
SIRT3 GNA11 0 0 44 176 1 1
SIRT3 BACE1 0 0 297 333 1 2
SIRT3 EHMT1 0 0 123 237 1 1
SIRT3 LIPT1 0 0 0 174 1 1
SIRT3 HMGB1 0 0 245 276 1 2
SIRT3 RBBP4 0 0 134 182 1 1
SIRT3 AFG3L2 0 0 74 157 1 1
SIRT3 ACOX1 0 0 244 260 1 1
SIRT3 CTSB 0 0 181 181 1 2
SIRT3 C1orf50 0 0 0 156 1 1
SIRT3 NOX1 0 0 286 286 1 1
SIRT3 TP53BP1 273 0 256 545 1 1
SIRT3 UBTF 0 0 143 178 1 1
SIRT3 CBX1 0 0 96 268 1 1
SIRT3 SMARCA4 0 0 251 293 1 1
SIRT3 SIRT1 0 0 924 346 1 2
SIRT3 MCL1 0 0 237 237 1 2
SIRT3 HIPK2 0 0 69 258 1 2
SIRT3 SMC1B 0 0 0 150 1 1
SIRT3 XBP1 0 0 233 234 1 2
SIRT3 PTPN1 0 0 290 298 1 1
SIRT3 ATG5 0 0 459 488 1 2
SIRT3 MTERF3 0 0 134 153 1 1
SIRT3 DUSP21 0 0 0 156 1 1
SIRT3 UQCRQ 0 0 60 226 1 1
SIRT3 POLE3 0 0 0 193 1 1
SIRT3 MT-ND1 0 0 203 380 1 1
SIRT3 TIA1 0 0 0 159 1 1
SIRT3 NDUFB8 0 0 202 360 1 1
SIRT3 FOXB1 0 0 0 166 1 1
SIRT3 POLE4 0 0 0 164 1 1
SIRT3 DUSP14 0 0 0 156 1 1
SIRT3 SMEK2 0 0 194 227 1 1
SIRT3 RANBP1 0 0 45 250 1 1
SIRT3 PMPCB 0 0 89 223 1 1
SIRT3 RT14 0 0 505 515 1 1
SIRT3 NDUFA8 0 0 0 183 1 1
SIRT3 HSPB1 0 0 181 225 1 2
SIRT3 DYRK1A 0 0 115 251 1 1
SIRT3 MGLL 0 0 123 187 1 1
SIRT3 HSPB2 0 0 150 196 1 1
SIRT3 TIAL1 0 0 0 159 1 1
SIRT3 KDM5B 0 0 148 215 1 1
SIRT3 GPX1 0 0 450 469 1 1
SIRT3 CARKD 0 0 0 230 1 1
SIRT3 RCOR1 0 0 369 369 1 1
SIRT3 GPX3 0 0 96 203 1 1
SIRT3 SOD3 0 0 261 284 1 1
SIRT3 HSPA5 94 0 278 405 1 2
SIRT3 FOXP2 0 0 0 196 1 1
SIRT3 E2F1 0 0 154 172 1 2
SIRT3 SMYD2 0 0 92 210 1 1
SIRT3 EIF4A2 0 0 0 156 1 1
SIRT3 HIST1H3J 0 0 48 191 1 1
SIRT3 MTUS1 0 0 413 413 1 1
SIRT3 TPTE2 0 0 0 156 1 1
SIRT3 FOXO1 0 900 632 967 1 2
SIRT3 EPAS1 0 0 147 222 1 2
SIRT3 HIST1H2BC 0 0 0 170 1 1
SIRT3 DUSP3 0 0 0 156 1 1
SIRT3 RANGRF 0 0 0 155 1 1
SIRT3 GPX2 0 0 57 217 1 1
SIRT3 SOD2 0 900 858 987 1 2
SIRT3 HEY2 0 0 120 204 1 1
SIRT3 YWHAZ 0 0 193 307 1 1
SIRT3 GHSR 0 0 96 152 1 1
SIRT3 FOS 0 0 253 311 1 2
SIRT3 TADA3 0 0 162 262 1 1
SIRT3 ADPRHL2 0 0 464 518 1 1
SIRT3 SUCLG2 0 0 55 164 1 1
SIRT3 CBR4 0 0 354 517 1 1
SIRT3 MSTN 0 0 201 201 1 1
SIRT3 PARP2 0 0 459 473 1 1
SIRT3 CNP 451 0 54 523 1 1
SIRT3 PSMD9 0 0 122 158 1 1
SIRT3 OTC 0 0 294 309 1 1
SIRT3 PTGES 0 0 54 307 1 1
SIRT3 MAOB 0 0 162 231 1 1
SIRT3 NDUFA6 0 0 53 164 1 1
SIRT3 FOXI2 0 0 0 166 1 1
SIRT3 CDKN2B 0 0 142 194 1 1
SIRT3 PIK3CB 0 0 81 226 1 1
SIRT3 CERS6 0 0 457 474 1 1
SIRT3 TLR2 0 0 151 165 1 2
SIRT3 PMAIP1 0 0 184 183 1 2
SIRT3 USMG5 0 0 55 240 1 1
SIRT3 LRP2 0 0 444 444 1 1
SIRT3 SLC5A2 0 0 164 165 1 1
SIRT3 ANKRD45 0 0 0 164 1 1
SIRT3 PHB 0 0 162 217 1 1
SIRT3 LRRK2 0 0 226 271 1 2
SIRT3 VIL1 0 0 0 207 1 1
SIRT3 HSPA4L 0 0 0 164 1 1
SIRT3 ATG12 0 0 269 304 1 2
SIRT3 TET1 0 0 265 265 1 1
SIRT3 SETD1B 0 0 81 268 1 1
SIRT3 TIPARP 0 0 175 175 1 1
SIRT3 TIMELESS 0 0 71 241 1 1
SIRT3 NR2C2 0 0 84 152 1 1
SIRT3 PPIA 0 0 157 177 1 1
SIRT3 GDF11 0 0 183 183 1 1
SIRT3 HAAO 0 0 101 157 1 1
SIRT3 TRPM2 0 0 181 181 1 2
SIRT3 ESRRG 0 0 160 192 1 1
SIRT3 DTYMK 0 0 53 190 1 1
SIRT3 ATG4D 0 0 96 165 1 2
SIRT3 GFPT1 0 0 74 161 1 1
SIRT3 HSPA1B 0 0 0 164 1 1
SIRT3 PITPNM3 0 0 0 191 1 1
SIRT3 KAT8 0 0 291 428 1 1
SIRT3 NQO1 0 0 374 377 1 2
SIRT3 FBP1 0 0 162 199 1 1
SIRT3 GHR 0 0 143 168 1 1
SIRT3 AK1 0 0 184 195 1 1
SIRT3 DHFR 0 0 127 232 1 1
SIRT3 MT-CO2 0 0 233 278 1 1
SIRT3 MEF2A 0 0 142 158 1 1
SIRT3 HIST3H3 0 0 0 185 1 1
SIRT3 PHB2 0 0 171 235 1 1
SIRT3 GPI 0 0 144 190 1 2
SIRT3 ATP5I 0 0 0 228 1 1
SIRT3 YWHAH 0 0 49 184 1 1
SIRT3 CRYAB 0 0 67 362 1 2
SIRT3 POLR1A 0 0 0 200 1 1
SIRT3 BRF2 0 0 0 202 1 1
SIRT3 HIGD1A 0 0 0 183 1 1
SIRT3 TFB2M 0 0 240 263 1 1
SIRT3 HDAC1 0 0 710 823 1 2
SIRT3 APLNR 0 0 180 179 1 1
SIRT3 UQCRHL 0 0 0 151 1 1
SIRT3 ERCC1 0 0 155 180 1 1
SIRT3 GK 0 0 127 150 1 1
SIRT3 FABP4 0 0 208 208 1 1
SIRT3 SFN 0 0 61 194 1 2
SIRT3 MPC2 0 0 137 212 1 1
SIRT3 ST14 0 0 265 265 1 1
SIRT3 PBRM1 0 0 74 219 1 1
SIRT3 XRCC5 0 0 233 328 1 1
SIRT3 HAT1 0 0 142 250 1 1
SIRT3 NDUFS8 0 0 171 353 1 1
SIRT3 DLAT 270 0 186 464 1 1
SIRT3 CUL3 0 0 140 243 1 2
SIRT3 HIST2H4A 0 0 560 643 1 1
SIRT3 HIST1H3I 0 0 48 191 1 1
SIRT3 HIST1H4F 270 0 560 728 1 1
SIRT3 ANKRD52 0 0 0 192 1 1
SIRT3 KAT6B 0 0 285 424 1 1
SIRT3 RAD51 0 0 234 302 1 2
SIRT3 NAT10 0 0 152 270 1 1
SIRT3 ATP5D 130 0 138 386 1 1
SIRT3 NDUFC2 0 0 0 307 1 1
SIRT3 SUV420H1 0 0 150 222 1 1
SIRT3 MTOR 0 0 607 638 1 2
SIRT3 AIM1 0 0 556 556 1 1
SIRT3 NDUFV3 0 0 113 169 1 1
SIRT3 JARID2 0 0 141 209 1 1
SIRT3 LSM14B 305 0 0 305 1 1
SIRT3 FLAD1 0 0 142 199 1 1
SIRT3 PIK3C3 0 0 206 370 1 2
SIRT3 CXXC1 0 0 95 156 1 1
SIRT3 UBN2 0 0 0 207 1 1
SIRT3 NPAS2 0 0 270 303 1 1
SIRT3 TCF20 0 0 71 191 1 1
SIRT3 CHD1L 0 0 107 157 1 1
SIRT3 H2BFWT 0 0 0 170 1 1
SIRT3 CPS1 0 0 425 448 1 1
SIRT3 EPHX2 0 0 52 232 1 1
SIRT3 CTRL 0 0 118 157 1 2
SIRT3 ART1 0 0 142 180 1 1
SIRT3 SFXN4 0 0 0 183 1 1
SIRT3 STAT1 0 0 204 204 1 2
SIRT3 ENDOG 0 0 181 231 1 1
SIRT3 THRA 0 0 95 155 1 1
SIRT3 UQCRC2 0 0 280 419 1 1
SIRT3 NR1H3 0 0 142 226 1 1
SIRT3 CXCL8 0 0 310 309 1 2
SIRT3 FSHB 0 0 60 266 1 1
SIRT3 HRAS 0 0 234 249 1 2
SIRT3 CTNNB1 0 0 391 406 1 2
SIRT3 EGR1 0 0 174 188 1 2
SIRT3 MFN2 0 0 519 565 1 2
SIRT3 APP 0 0 422 423 1 2
SIRT3 ORC1 0 0 0 267 1 1
SIRT3 BAZ1A 0 0 52 200 1 1
SIRT3 PNPT1 0 0 119 198 1 1
SIRT3 TMEM14C 0 0 0 272 1 1
SIRT3 COQ9 0 0 49 188 1 1
SIRT3 NDUFA12 0 0 74 298 1 1
SIRT3 DMGDH 0 0 124 162 1 1
SIRT3 PDHA1 270 0 381 586 1 1
SIRT3 ART5 0 0 241 240 1 1
SIRT3 FOXB2 0 0 0 166 1 1
SIRT3 KAT6A 0 0 391 509 1 1
SIRT3 NFKB1 0 0 112 166 1 2
SIRT3 MT-ATP8 0 0 108 164 1 1
SIRT3 STRADA 0 0 104 275 1 1
SIRT3 COX5B 0 0 96 228 1 1
SIRT3 KMT2E 0 0 66 198 1 1
SIRT3 CARM1 0 0 218 249 1 2
SIRT3 RELA 0 0 393 403 1 2
SIRT3 DUPD1 0 0 0 156 1 1
SIRT3 ENO1 0 0 166 177 1 1
SIRT3 NNT 0 900 323 934 1 1
SIRT3 TMED7 0 0 0 175 1 1
SIRT3 PML 0 0 146 163 1 2
SIRT3 DUSP5 0 0 74 230 1 1
SIRT3 TRIM43 418 0 0 430 1 1
SIRT3 GAPDH 0 0 509 593 1 2
SIRT3 CYP1A1 0 0 154 153 1 2
SIRT3 DNAI1 0 0 0 193 1 1
SIRT3 HDAC10 0 0 636 750 1 1
SIRT3 MAP2K7 0 0 229 228 1 1
SIRT3 HIST4H4 0 0 560 643 1 1
SIRT3 ACO2 0 0 322 512 1 1
SIRT3 BIVM-ERCC5 0 0 0 168 1 1
SIRT3 NFE2 0 0 170 200 1 1
SIRT3 SDHB 130 0 261 548 1 1
SIRT3 ESRRA 0 0 561 597 1 1
SIRT3 PIEZO2 0 0 181 181 1 1
SIRT3 PFKFB3 0 0 320 345 1 2
SIRT3 TIMM22 0 0 0 195 1 1
SIRT3 HCAR2 0 0 275 275 1 1
SIRT3 PPCS 0 0 0 333 1 1
SIRT3 FOXD4L1 0 0 0 166 1 1
SIRT3 CREBBP 0 0 391 486 1 1
SIRT3 PPID 0 0 324 347 1 1
SIRT3 CKAP5 0 0 0 178 1 1
SIRT3 GCKR 0 0 154 153 1 1
SIRT3 ATP5E 0 0 74 170 1 1
SIRT3 BCKDHB 0 0 0 187 1 1
SIRT3 ZNFX1 0 0 0 174 1 1
SIRT3 HIST2H2AC 0 0 464 492 1 1
SIRT3 GCSH 0 0 46 226 1 1
SIRT3 GZMM 0 0 61 205 1 1
SIRT3 CREB1 0 650 505 819 1 2
SIRT3 KDM4E 0 0 148 161 1 1
SIRT3 TEF 0 0 125 177 1 1
SIRT3 ALDH3B2 0 0 0 203 1 1
SIRT3 POLR2A 0 0 83 235 1 1
SIRT3 IBA57 0 0 0 260 1 1
SIRT3 SLC25A6 0 0 161 276 1 1
SIRT3 SIRT2 0 0 806 175 1 2
SIRT3 UGDH 94 0 0 202 1 1
SIRT3 HSF1 0 0 163 218 1 2
SIRT3 SLC2A3 0 0 172 196 1 1
SIRT3 MKNK2 0 0 0 206 1 1
SIRT3 MDC1 0 0 67 203 1 1
SIRT3 GCDH 0 0 125 150 1 1
SIRT3 ACTA1 0 0 106 155 1 1
SIRT3 SUCNR1 0 0 218 218 1 1
SIRT3 NDUFS3 0 0 245 348 1 1
SIRT3 DUSP4 0 0 0 156 1 1
SIRT3 HIST1H2BH 0 0 0 170 1 1
SIRT3 RB1CC1 0 0 193 211 1 2
SIRT3 NAP1L2 0 0 0 192 1 1
SIRT3 STK11 0 0 556 570 1 2
SIRT3 BRCA1 0 0 367 367 1 2
SIRT3 OPA1 270 0 158 473 1 2
SIRT3 TOP2A 0 0 74 187 1 1
SIRT3 BOLA2 0 0 0 152 1 1
SIRT3 FOXN3 0 0 0 166 1 1
SIRT3 PPRC1 0 0 181 290 1 1
SIRT3 DGAT1 0 0 137 199 1 2
SIRT3 ETHE1 270 0 95 329 1 1
SIRT3 ILK 0 0 108 195 1 1
SIRT3 CLOCK 0 0 505 527 1 2
SIRT3 CBX5 0 0 95 235 1 1
SIRT3 NDUFS6 0 0 74 194 1 1
SIRT3 PARK2 0 0 391 399 1 1
SIRT3 NR0B2 0 0 148 180 1 1
SIRT3 HTR1B 0 0 49 150 1 1
SIRT3 NDUFA11 0 0 347 513 1 1
SIRT3 CDC14A 0 0 181 282 1 1
SIRT3 BLOC1S1 0 0 517 536 1 1
SIRT3 ADAM10 0 0 252 252 1 1
SIRT3 FOXR2 0 0 0 166 1 1
SIRT3 PCK1 0 0 341 347 1 1
SIRT3 PPARGC1A 0 900 906 991 1 2
SIRT3 P4HB 0 0 107 152 1 2
SIRT3 GPX7 0 0 48 232 1 1
SIRT3 RICTOR 0 0 235 272 1 2
SIRT3 G6PC 0 0 342 361 1 1
SIRT3 EGLN3 0 0 140 158 1 1
SIRT3 GNAQ 0 0 95 219 1 1
SIRT3 TOP1 0 0 193 247 1 1
SIRT3 HNF4G 0 0 0 157 1 1
SIRT3 UBXN7 0 0 0 210 1 1
SIRT3 MICU1 0 0 143 162 1 1
SIRT3 HSPA12B 0 0 0 164 1 1
SIRT3 GHRL 0 0 245 244 1 1
SIRT3 JAK2 0 0 180 191 1 2
SIRT3 HDAC6 0 0 702 795 1 2
SIRT3 APAF1 0 0 218 243 1 2
SIRT3 MKNK1 0 0 0 156 1 1
SIRT3 RAD9A 0 0 134 154 1 1
SIRT3 BRD4 0 0 280 392 1 2
SIRT3 PPARD 0 0 134 239 1 1
SIRT3 CISD2 0 0 69 255 1 2
SIRT3 NR4A1 0 0 160 159 1 2
SIRT3 NQO2 0 0 140 174 1 1
SIRT3 IMPDH2 0 0 0 150 1 1
SIRT3 CENPA 0 0 73 213 1 1
SIRT3 PMPCA 0 0 59 183 1 1
SIRT3 HIST1H2BI 0 0 0 170 1 1
SIRT3 MYH6 0 0 208 220 1 1
SIRT3 NDUFS1 0 0 261 452 1 1
SIRT3 SUPV3L1 0 0 108 151 1 1
SIRT3 EIF2AK4 0 0 247 250 1 2
SIRT3 TBRG1 0 0 0 165 1 1
SIRT3 SUCLG1 0 0 95 235 1 1
SIRT3 PHF7 0 0 0 165 1 1
SIRT3 NCOA1 0 0 123 186 1 1
SIRT3 HAGH 0 0 150 254 1 1
SIRT3 GDNF 0 0 150 188 1 2
SIRT3 PRPSAP1 0 0 0 151 1 1
SIRT3 MAOA 0 0 188 255 1 1
SIRT3 TP53 0 0 778 781 1 2
SIRT3 MDM2 270 0 378 526 1 2
SIRT3 HMGCS1 0 0 165 180 1 1
SIRT3 SLC2A1 0 0 408 425 1 2
SIRT3 OARD1 0 0 370 388 1 1
SIRT3 HTT 0 0 459 483 1 2
SIRT3 CFLAR 0 0 134 267 1 2
SIRT3 EGFR 0 0 264 271 1 2
SIRT3 OPLAH 0 0 0 346 1 1
SIRT3 UQCRH 94 0 90 380 1 1
SIRT3 ME2 0 0 67 155 1 1
SIRT3 NCOR2 0 0 288 430 1 1
SIRT3 BST1 0 650 519 824 1 1
SIRT3 CUL2 0 0 67 178 1 1
SIRT3 FAM210A 0 0 0 183 1 1
SIRT3 TNS3 0 0 0 156 1 1
SIRT3 ADAT2 0 0 66 268 1 1
SIRT3 HDAC2 0 0 681 805 1 1
SIRT3 MAP1A 0 0 170 180 1 2
SIRT3 DUT 0 0 63 170 1 1
SIRT3 HIST1H2BO 0 0 0 170 1 1
SIRT3 AGER 0 0 161 161 1 2
SIRT3 ALDH3A2 0 0 54 192 1 1
SIRT3 HSPA14 0 0 0 164 1 1
SIRT3 DUSP8 0 0 0 156 1 1
SIRT3 ASL 0 0 113 156 1 1
SIRT3 AMD1 0 0 54 200 1 1
SIRT3 SIRT6 0 0 797 457 1 2
SIRT3 CTH 0 0 155 154 1 1
SIRT3 BCL2L13 0 0 120 161 1 2
SIRT3 TMEM126A 0 0 0 228 1 1
SIRT3 GFOD1 0 0 0 165 1 1
SIRT3 BUB1B 0 0 260 279 1 1
SIRT3 FNDC5 0 0 211 211 1 1
SIRT3 DUSP10 0 0 0 156 1 1
SIRT3 EPM2A 0 0 0 156 1 2
SIRT3 IDH1 0 0 315 339 1 1
SIRT3 COX10 0 0 171 171 1 1
SIRT3 HES7 0 0 0 199 1 1
SIRT3 CALML3 0 0 50 167 1 1
SIRT3 CDH1 0 0 270 270 1 2
SIRT3 H3F3B 0 0 48 207 1 1
SIRT3 MIEF2 0 0 234 234 1 1
SIRT3 GATA1 0 0 172 171 1 1
SIRT3 AANAT 0 0 117 197 1 1
SIRT3 PDE4A 0 0 138 203 1 1
SIRT3 INVS 0 0 0 195 1 1
SIRT3 AVP 0 0 178 177 1 1
SIRT3 BDH2 0 0 0 154 1 1
SIRT3 NMNAT2 0 650 659 893 1 1
SIRT3 PPP1CB 0 0 0 153 1 1
SIRT3 IDO1 0 0 126 151 1 1
SIRT3 SGK2 0 0 0 157 1 1
SIRT3 ALB 0 0 427 439 1 2
SIRT3 CCL2 0 0 322 321 1 2
SIRT3 DUSP9 0 0 0 156 1 1
SIRT3 DUSP7 0 0 0 156 1 1
SIRT3 ELAVL1 0 0 162 161 1 2
SIRT3 PITPNM1 0 0 0 191 1 1
SIRT3 CUL1 0 0 74 184 1 1
SIRT3 CASP7 0 0 141 184 1 1
SIRT3 ADIPOR1 0 0 150 203 1 1
SIRT3 CHD1 0 0 124 180 1 1
SIRT3 CDK5 0 0 283 311 1 2
SIRT3 EP300 0 0 601 663 1 2
SIRT3 ACSS1 847 900 595 994 1 1
SIRT3 TEFM 0 0 0 183 1 1
SIRT3 TPTE 0 0 48 162 1 1
SIRT3 NMRK1 0 0 520 529 1 1
SIRT3 MRPL10 0 0 664 675 1 1
SIRT3 DBT 0 0 0 151 1 2
SIRT3 ENSG00000267318 0 0 0 157 1 1
SIRT3 IL4 0 0 170 169 1 1
SIRT3 SMAD3 0 0 294 396 1 2
SIRT3 CRY2 0 0 234 310 1 1
SIRT3 SNCAIP 0 0 113 167 1 2
SIRT3 REC8 0 0 0 154 1 1
SIRT3 ROCK1 0 0 129 152 1 2
SIRT3 PAICS 0 0 90 171 1 1
SIRT3 DUSP12 0 0 66 178 1 1
SIRT3 CYCS 0 0 560 600 1 2
SIRT3 PDP1 270 0 52 395 1 1
SIRT3 HIST2H2BF 0 0 0 170 1 1
SIRT3 SENP1 0 0 126 199 1 1
SIRT3 IGFBP1 0 0 181 181 1 1
SIRT3 ATP5A1 302 0 208 538 1 1
SIRT3 PHF20L1 0 0 46 228 1 1
SIRT3 HNF1A 0 0 147 199 1 1
SIRT3 EGF 0 0 223 223 1 2
SIRT3 GAK 0 0 0 254 1 1
SIRT3 CDC6 0 0 74 292 1 1
SIRT3 HSPA4 94 0 443 542 1 1
SIRT3 ZDHHC13 0 0 81 184 1 1
SIRT3 POLR1E 0 0 218 240 1 1
SIRT3 SMARCA2 0 0 163 214 1 1
SIRT3 GATA4 0 0 216 216 1 2
SIRT3 ACSF3 0 0 124 191 1 1
SIRT3 PITPNC1 0 0 0 191 1 1
SIRT3 PRPS1L1 0 0 45 155 1 1
SIRT3 DICER1 0 0 193 277 1 1
SIRT3 DYRK3 0 0 108 253 1 1
SIRT3 LPIN3 0 0 43 170 1 1
SIRT3 HSP90B1 94 0 112 192 1 1
SIRT3 CYP2E1 0 0 241 257 1 2
SIRT3 HSPB3 0 0 167 173 1 1
SIRT3 PEX11B 0 0 0 174 1 1
SIRT3 MT-ATP6 0 0 218 325 1 1
SIRT3 NAP1L5 0 0 0 192 1 1
SIRT3 CETP 0 0 123 265 1 1
SIRT3 PPARA 0 0 595 610 1 2
SIRT3 HMGCL 0 0 218 259 1 1
SIRT3 ACHE 0 0 204 204 1 2
SIRT3 LPL 0 0 186 186 1 1
SIRT3 TEK 0 0 150 188 1 1
SIRT3 SSH1 0 0 0 156 1 1
SIRT3 TUFM 0 0 55 175 1 2
SIRT3 GPX4 0 0 260 358 1 2
SIRT3 BLVRA 0 0 0 191 1 1
SIRT3 SESN2 0 0 172 171 1 2
SIRT3 NAP1L3 0 0 0 192 1 1
SIRT3 HSDL2 270 0 90 333 1 1
SIRT3 NDUFS7 130 0 73 374 1 1
SIRT3 KDM2A 0 0 155 286 1 1
SIRT3 DIABLO 0 0 124 161 1 2
SIRT3 MTR 0 0 188 214 1 1
SIRT3 HIBADH 0 0 0 313 1 1
SIRT3 H2AFY2 0 0 86 170 1 1
SIRT3 TDP2 0 0 74 171 1 1
SIRT3 BAZ1B 0 0 89 231 1 1
SIRT3 GPD1L 0 0 82 158 1 1
SIRT3 DNAJC19 0 0 57 159 1 1
SIRT3 SAMD1 0 0 0 227 1 1
SIRT3 NMNAT3 0 650 547 857 1 1
SIRT3 PHF8 0 0 106 229 1 1
SIRT3 PEX5 310 0 103 370 1 1
SIRT3 XRCC1 0 0 193 193 1 1
SIRT3 MAPK8 0 0 307 368 1 2
SIRT3 MIPEP 0 0 172 272 1 1
SIRT3 TNS4 0 0 0 156 1 1
SIRT3 IMPDH1 0 0 0 150 1 1
SIRT3 HIST1H2BK 0 0 0 170 1 1
SIRT3 MFN1 0 0 470 553 1 2
SIRT3 IRS2 0 0 398 412 1 1
SIRT3 SORD 0 0 108 169 1 1
SIRT3 SMAD1 0 0 48 186 1 2
SIRT3 NDUFB2 0 0 112 203 1 1
SIRT3 NCOA3 0 0 209 245 1 1
SIRT3 ENSG00000270024 0 0 0 157 1 1
SIRT3 POFUT2 0 0 0 245 1 1
SIRT3 H3F3C 0 0 0 201 1 1
SIRT3 COX6C 0 0 0 202 1 1
SIRT3 INSIG2 0 0 102 196 1 1
SIRT3 CDC14B 0 0 0 159 1 1
SIRT3 FTSJ2 0 0 66 211 1 1
SIRT3 BMI1 0 0 162 180 1 1
SIRT3 SMC3 0 0 141 255 1 1
SIRT3 SMC1A 0 0 51 159 1 1
SIRT3 ARNT 0 0 262 295 1 2
SIRT3 TBL1X 0 0 143 206 1 1
SIRT3 SOD1 0 0 416 443 1 2
SIRT3 SP6 0 0 151 166 1 1
SIRT3 PARP14 0 0 223 255 1 1
SIRT3 FGF6 0 0 194 194 1 1
SIRT3 NTHL1 0 0 69 203 1 1
SIRT3 NPPB 0 0 193 193 1 1
SIRT3 LONP2 0 0 123 201 1 1
SIRT3 SLC16A4 0 0 226 225 1 1
SIRT3 CYP19A1 0 0 155 154 1 2
SIRT3 PARD3B 0 0 0 187 1 1
SIRT3 DNAJA3 0 0 442 454 1 1
SIRT3 ASF1A 0 0 57 267 1 1
SIRT3 JUN 0 0 407 422 1 2
SIRT3 ASF1B 0 0 0 255 1 1
SIRT3 TAF1 0 0 280 316 1 1
SIRT3 DNTT 0 0 155 173 1 1
SIRT3 COX15 0 0 92 474 1 1
SIRT3 NCOA2 0 0 157 195 1 1
SIRT3 TK1 0 0 0 181 1 1
SIRT3 NOS1 0 0 190 215 1 1
SIRT3 CCNA2 0 0 229 309 1 1
SIRT3 PRAM1 0 0 113 202 1 1
SIRT3 SIX4 0 0 66 320 1 1
SIRT3 DHRS11 0 0 91 172 1 1
SIRT3 HIC1 0 0 265 278 1 1
SIRT3 KMO 0 0 108 152 1 1
SIRT3 PIK3CG 0 0 63 150 1 1
SIRT3 YEATS4 0 0 120 162 1 1
SIRT3 HIST2H2AA 0 0 464 492 1 1
SIRT3 WHSC1L1 0 0 112 227 1 1
SIRT3 ATG13 0 0 202 202 1 2
SIRT3 RAD21L1 0 0 0 154 1 1
SIRT3 BNIP3 0 0 406 434 1 2
SIRT3 SQSTM1 0 0 297 302 1 2
SIRT3 SLC16A1 0 0 163 163 1 1
SIRT3 ATP5O 0 0 721 755 1 1
SIRT3 PCK2 0 0 210 217 1 1
SIRT3 CRYZ 0 0 174 266 1 1
SIRT3 CUL4A 0 0 0 155 1 1
SIRT3 ING3 0 0 81 208 1 1
SIRT3 MAPK3 0 0 325 372 1 2
SIRT3 KLF15 0 0 204 218 1 1
SIRT3 MMP9 0 0 309 310 1 2
SIRT3 HDAC4 0 0 702 795 1 2
SIRT3 HIST2H2AA3 0 0 464 492 1 1
SIRT3 HSP90AA1 0 0 459 479 1 2
SIRT3 CTBP1 0 0 194 200 1 1
SIRT3 SBF1 94 0 0 454 1 1
SIRT3 DHPS 0 0 159 179 1 1
SIRT3 CRP 0 0 287 286 1 2
SIRT3 ASS1 130 0 95 232 1 1
SIRT3 MUL1 0 0 161 179 1 2
SIRT3 ATF2 0 0 122 190 1 1
SIRT3 RAB29 0 0 0 219 1 1
SIRT3 PSEN1 0 0 369 369 1 2
SIRT3 SOX2 0 0 218 232 1 2
SIRT3 UMPS 0 0 44 168 1 1
SIRT3 NAP1L6 0 0 0 192 1 1
SIRT3 EHHADH 0 0 212 218 1 1
SIRT3 YEATS2 0 0 180 220 1 1
SIRT3 CKM 0 0 156 155 1 1
SIRT3 DMC1 305 0 0 367 1 1
SIRT3 ICAM1 0 0 260 263 1 2
SIRT3 ZMYND15 0 0 0 165 1 1
SIRT3 SLC25A14 0 0 233 289 1 1
SIRT3 NFS1 0 0 0 205 1 1
SIRT3 FOXA3 0 0 66 203 1 1
SIRT3 AR 0 0 248 277 1 2
SIRT3 HIST1H3D 0 0 76 215 1 1
SIRT3 GSN 0 0 81 240 1 1
SIRT3 CDKN1A 0 0 325 345 1 2
SIRT3 LRRC46 0 0 83 169 1 1
SIRT3 BAX 0 0 232 241 1 2
SIRT3 AURKA 0 0 74 184 1 2
SIRT3 DUSP16 0 0 0 156 1 1
SIRT3 SLK 0 0 216 216 1 1
SIRT3 HSPA12A 0 0 0 164 1 1
SIRT3 G2E3 0 0 0 165 1 1
SIRT3 SCD 0 0 211 211 1 1
SIRT3 EED 0 0 123 225 1 1
SIRT3 SRC 0 0 292 292 1 2
SIRT3 ATP5J2 0 0 92 368 1 1
SIRT3 KDM6A 0 0 218 318 1 1
SIRT3 DUSP19 0 0 0 156 1 1
SIRT3 PCSK9 0 0 166 176 1 1
SIRT3 ETFDH 0 0 150 316 1 1
SIRT3 YWHAB 0 0 74 209 1 1
SIRT3 HSD17B8 0 0 0 224 1 1
SIRT3 DHFRL1 0 0 0 156 1 1
SIRT3 MCU 0 0 299 328 1 2
SIRT3 DENND5A 0 0 0 189 1 1
SIRT3 NAT1 0 0 95 154 1 1
SIRT3 PAPD5 0 0 0 161 1 1
SIRT3 ACLY 0 0 458 498 1 1
SIRT3 ING2 0 0 61 190 1 1
SIRT3 FOXJ2 0 0 0 204 1 1
SIRT3 EIF2AK3 0 0 248 248 1 2
SIRT3 VHL 0 0 181 186 1 2
SIRT3 COASY 0 0 243 280 1 1
SIRT3 SLC25A5 0 0 247 350 1 1
SIRT3 H6PD 0 0 181 390 1 1
SIRT3 NDUFA4L2 0 0 166 167 1 1
SIRT3 NDUFA1 0 0 210 210 1 1
SIRT3 LDHB 0 0 117 162 1 1
SIRT3 EIF2S1 0 0 202 202 1 2
SIRT3 ERAL1 0 0 95 157 1 1
SIRT3 ELK4 0 0 157 156 1 1
SIRT3 TOMM20 0 0 347 374 1 2
SIRT3 GLRX 0 0 204 221 1 1
SIRT3 ATP5H 0 0 92 568 1 1
SIRT3 DNMT3L 0 0 193 193 1 1
SIRT3 TRAPPC6B 0 0 0 171 1 1
SIRT3 TCHP 0 0 365 365 1 1
SIRT3 KDM5A 0 0 202 265 1 1
SIRT3 ING4 0 0 0 173 1 1
SIRT3 HMOX1 0 0 466 487 1 2
SIRT3 CDKN1B 0 0 171 211 1 2
SIRT3 DUSP13 0 0 0 156 1 1
SIRT3 BET1L 0 0 258 258 1 1
SIRT3 GTF2B 0 0 53 257 1 1
SIRT3 POLRMT 0 0 252 271 1 1
SIRT3 ZFYVE1 0 0 112 161 1 2
SIRT3 ATP5G2 0 0 95 195 1 1
SIRT3 RB1 0 0 164 189 1 2
SIRT3 OXSM 0 0 0 246 1 1
SIRT3 TSC2 0 0 286 301 1 2
SIRT3 TRRAP 0 0 125 194 1 1
SIRT3 ATP5C1 0 0 117 239 1 1
SIRT3 BNIP3L 0 0 341 346 1 2
SIRT3 PTPDC1 0 0 0 156 1 1
SIRT3 NUDT12 0 900 72 913 1 1
SIRT3 ATF4 0 0 213 213 1 2
SIRT3 CD4 0 0 231 230 1 2
SIRT3 HIST1H2BA 0 0 46 174 1 1
SIRT3 FOXA1 0 0 108 249 1 1
SIRT3 PRDM16 0 0 241 254 1 1
SIRT3 SGK3 0 0 43 159 1 1
SIRT3 NDUFA5 0 0 112 237 1 1
SIRT3 PHF2 0 0 0 169 1 1
SIRT3 DUSP23 0 0 0 156 1 1
SIRT3 PPARG 0 0 602 622 1 2
SIRT3 APLN 0 0 181 181 1 1
SIRT3 BHMT 0 0 120 166 1 1
SIRT3 AKT1 0 0 602 622 1 2
SIRT3 RUNX2 0 0 219 219 1 2
SIRT3 ARHGEF26 263 0 0 279 1 1
SIRT3 PPP2R4 0 0 195 195 1 1
SIRT3 XIAP 0 0 165 238 1 2
SIRT3 SLC25A3 0 0 97 216 1 1
SIRT3 RAI1 0 0 0 165 1 1
SIRT3 KLF4 0 0 183 197 1 2
SIRT3 IKBKB 0 0 188 188 1 2
SIRT3 LETM1 0 0 114 226 1 1
SIRT3 ATF6 0 0 194 194 1 2
SIRT3 ACE2 0 0 167 167 1 2
SIRT3 CARS2 0 0 0 248 1 1
SIRT3 BRDT 0 0 243 361 1 1
SIRT3 ABCG8 0 0 66 196 1 1
SIRT3 TAF3 0 0 0 194 1 1
SIRT3 MTX2 0 0 0 229 1 1
SIRT3 ING5 0 0 0 173 1 1
SIRT3 HIST3H2BB 0 0 0 170 1 1
SIRT3 SMC4 0 0 47 153 1 1
SIRT3 WDHD1 0 0 66 233 1 1
SIRT3 SIRT4 270 0 765 592 1 1
SIRT3 ATOH1 0 0 70 162 1 1
SIRT3 FOXE1 0 0 0 166 1 1
SIRT3 NDUFB6 0 0 95 329 1 1
SIRT3 FOXD4L3 0 0 0 166 1 1
SIRT3 BBC3 0 0 154 153 1 2
SIRT3 PARP6 0 0 151 150 1 1
SIRT3 HIST1H3G 0 0 48 191 1 1
SIRT3 ARG2 0 0 205 215 1 1
SIRT3 ERBB2 0 0 218 226 1 2
SIRT3 FOXF2 0 0 0 166 1 1
SIRT3 ENSG00000274276 0 0 164 163 1 1
SIRT3 PRDX3 0 0 329 420 1 1
SIRT3 CDYL2 0 0 0 189 1 1
SIRT3 TOP1MT 0 0 147 300 1 1
SIRT3 RIC8A 0 0 282 297 1 1
SIRT3 GFPT2 0 0 82 168 1 1
SIRT3 YME1L1 0 0 180 226 1 1
SIRT3 NR1I2 0 0 134 167 1 1
SIRT3 SMC5 0 0 60 163 1 1
SIRT3 PRLR 0 0 0 293 1 1
SIRT3 TXNIP 0 0 294 326 1 2
SIRT3 FKBP1C 0 0 142 152 1 1
SIRT3 DGUOK 0 0 47 160 1 1
SIRT3 DRAM1 0 0 150 162 1 2
SIRT3 ZMPSTE24 0 0 166 433 1 1
SIRT3 TOMM5 0 0 0 192 1 1
SIRT3 REST 0 0 150 165 1 2
SIRT3 RAB7A 0 0 150 168 1 2
SIRT3 GLRX2 0 0 217 234 1 1
SIRT3 GCG 0 0 391 390 1 1
SIRT3 ATG4B 0 0 134 197 1 2
SIRT3 PARP15 0 0 241 273 1 1
SIRT3 HIST1H2BF 0 0 0 170 1 1
SIRT3 GSTP1 0 0 180 179 1 1
SIRT3 CCND2 0 0 92 188 1 1
SIRT3 NUDT5 0 0 232 286 1 1
SIRT3 AGT 0 0 66 358 1 1
SIRT3 SLC38A3 0 0 150 155 1 1
SIRT3 ARNTL 0 0 518 546 1 1
SIRT3 EZH1 0 0 112 227 1 1
SIRT3 AGK 0 0 246 361 1 1
SIRT3 PARP3 0 0 343 360 1 1
SIRT3 FOXL2 0 0 0 166 1 1
SIRT3 NDUFV1 0 0 166 279 1 1
SIRT3 ATF3 0 0 123 191 1 2
SIRT3 PGAM1 0 0 234 269 1 1
SIRT3 RETN 0 0 181 181 1 1
SIRT3 MMP3 0 0 171 172 1 1
SIRT3 FBXO18 0 0 0 178 1 1
SIRT3 VDR 0 0 146 178 1 2
SIRT3 TMEM167A 0 0 0 359 1 1
SIRT3 TRAP1 0 0 155 204 1 2
SIRT3 KDM3A 0 0 247 246 1 1
SIRT3 LPIN2 0 0 74 197 1 1
SIRT3 SIN3A 0 0 246 299 1 1
SIRT3 MEF2C 0 0 141 157 1 1
SIRT3 NT5E 0 0 146 156 1 1
SIRT3 GFER 0 0 86 167 1 1
SIRT3 UQCRC1 0 0 170 353 1 1
SIRT3 NFYC 0 0 0 164 1 1
SIRT3 IDH3B 0 0 57 164 1 1
SIRT3 STK32C 0 0 0 175 1 1
SIRT3 DNAJC6 0 0 0 171 1 1
SIRT3 TNF 0 0 460 467 1 2
SIRT3 EEF2 0 0 138 167 1 2
SIRT3 RBBP7 0 0 138 186 1 1
SIRT3 ATXN7 0 0 124 242 1 1
SIRT3 MLYCD 0 0 504 519 1 1
SIRT3 MDH1 0 0 203 262 1 1
SIRT3 UNC119B 0 0 0 154 1 1
SIRT3 WIPI2 0 0 74 174 1 2
SIRT3 ALDH18A1 0 0 45 188 1 1
SIRT3 ALDH7A1 0 0 181 193 1 1
SIRT3 SDHAF1 0 0 134 168 1 1
SIRT3 FIS1 0 0 491 522 1 2
SIRT3 GH1 0 0 112 167 1 1
SIRT3 SMAD6 0 0 71 162 1 1
SIRT3 FOXA2 0 0 97 239 1 1
SIRT3 PITPNA 94 0 0 469 1 1
SIRT3 RPA1 0 0 95 186 1 1
SIRT3 BAK1 0 0 113 329 1 2
SIRT3 HPRT1 0 0 150 176 1 1
SIRT3 SSH3 0 0 0 179 1 1
SIRT3 AARS 0 0 95 163 1 1
SIRT3 DDIT4 0 0 157 156 1 2
SIRT3 BCAT2 0 0 142 368 1 1
SIRT3 COX7B 0 0 55 221 1 1
SIRT3 MTRF1L 0 0 0 153 1 1
SIRT3 SLC27A1 0 0 159 177 1 1
SIRT3 ANKRD50 0 0 0 192 1 1
SIRT3 BLM 0 0 43 203 1 2
SIRT3 MT-ND5 0 0 81 262 1 1
SIRT3 ACOT13 0 0 53 276 1 1
SIRT3 AVIL 0 0 0 207 1 1
SIRT3 DUSP6 0 0 66 178 1 1
SIRT3 HELZ2 0 0 0 269 1 1
SIRT3 ELMO2 0 0 0 179 1 1
SIRT3 CAT 0 0 651 674 1 2
SIRT3 POU5F1 0 0 206 222 1 2
SIRT3 TMEM230 0 0 0 240 1 1
SIRT3 SMYD5 0 0 0 165 1 1
SIRT3 HIST1H3F 0 0 48 191 1 1
SIRT3 BMPR2 0 0 134 165 1 1
SIRT3 ACAT1 0 0 315 340 1 1
SIRT3 LOX 0 0 150 173 1 2
SIRT3 TRMT2A 0 0 82 262 1 1
SIRT3 HSPA9 94 0 270 544 1 1
SIRT3 IRS1 0 0 334 350 1 2
SIRT3 SGK1 0 0 181 280 1 2
SIRT3 C10orf2 0 0 181 207 1 1
SIRT3 FOXD4 0 0 0 166 1 1
SIRT3 SERPINE1 0 0 243 243 1 1
SIRT3 PDHB 270 0 205 474 1 1
SIRT3 AHR 0 0 260 260 1 2
SIRT3 DOT1L 0 0 324 446 1 1
SIRT3 CDK1 0 0 270 302 1 2
SIRT3 NCOR1 0 0 456 564 1 1
SIRT3 HIST1H4B 0 0 560 643 1 1
SIRT3 PGR 0 0 442 464 1 1
SIRT3 AGTR1 0 0 294 294 1 1
SIRT3 RPS6KB1 0 0 422 492 1 2
SIRT3 C14orf2 0 0 0 154 1 1
SIRT3 PC 0 0 270 336 1 1
SIRT3 DUSP18 0 0 0 156 1 1
SIRT3 HDAC7 0 0 596 722 1 1
SIRT3 SREBF2 0 0 262 289 1 1
SIRT3 SBNO1 0 0 0 156 1 1
SIRT3 ALDH2 486 0 390 681 1 2
SIRT3 MTIF3 0 0 0 187 1 1
SIRT3 PAXIP1 0 0 66 190 1 1
SIRT3 ATR 0 0 163 229 1 2
SIRT3 SMYD1 0 0 136 248 1 1
SIRT3 FOXC2 0 0 112 227 1 1
SIRT3 DENND5B 0 0 0 189 1 1
SIRT3 ATP5L 0 0 66 235 1 1
SIRT3 GOT2 0 0 211 278 1 1
SIRT3 OGT 0 0 143 159 1 2
SIRT3 IGF2 0 0 247 246 1 1
SIRT3 NDUFS2 0 0 103 160 1 1
SIRT3 CECR2 0 0 56 203 1 1
SIRT3 UNG 0 0 103 162 1 1
SIRT3 KDM4C 0 0 141 154 1 1
SIRT3 IL10 0 0 299 299 1 2
SIRT3 SNAI1 0 0 208 208 1 1
SIRT3 TAF1L 0 0 273 309 1 1
SIRT3 NPM1 0 0 124 183 1 1
SIRT3 FOSB 0 0 119 187 1 1
SIRT3 FOXD4L6 0 0 0 166 1 1
SIRT3 HCAR1 0 0 408 408 1 1
SIRT3 DYRK1B 0 0 0 213 1 1
SIRT3 PRPS1 0 0 49 158 1 1
SIRT3 DLG4 0 0 151 186 1 2
SIRT3 NR1H4 0 0 294 321 1 1
SIRT3 BHLHE41 0 0 81 215 1 1
SIRT3 GAPDHS 0 0 0 213 1 1
SIRT3 NUDT1 0 0 82 230 1 1
SIRT3 DUSP28 0 0 0 156 1 1
SIRT3 TERF1 0 0 162 171 1 1
SIRT3 PPIL4 0 0 0 162 1 1
SIRT3 AASDHPPT 0 0 74 168 1 1
SIRT3 RECQL5 0 0 47 206 1 1
SIRT3 NME8 0 0 0 189 1 1
SIRT3 MMP11 0 0 392 393 1 1
SIRT3 SLC2A14 0 0 193 217 1 1
SIRT3 FOXL1 0 0 0 166 1 1
SIRT3 SLC9C2 0 0 0 164 1 1
SIRT3 ACSM1 0 0 95 151 1 1
SIRT3 YARS 0 0 103 157 1 1
SIRT3 KAT5 0 0 463 567 1 1
SIRT3 E2F3 0 0 136 154 1 1
SIRT3 NGFR 0 0 450 450 1 1
SIRT3 HIST1H4K 0 0 560 643 1 1
SIRT3 YARS2 0 0 140 175 1 1
SIRT3 TMED4 0 0 0 162 1 1
SIRT3 LDHA 0 0 390 415 1 2
SIRT3 AMBRA1 0 0 178 214 1 2
SIRT3 RARB 0 0 170 202 1 1
SIRT3 HIST1H3B 0 0 48 191 1 1
SIRT3 H2BFS 0 0 0 170 1 1
SIRT3 NFE2L1 0 0 90 150 1 1
SIRT3 COMMD3-BMI1 0 0 156 174 1 1
SIRT3 PNMAL2 0 0 0 206 1 1
SIRT3 SMAD7 0 0 215 292 1 1
SIRT3 SENP3 0 0 95 164 1 1
SIRT3 H2AFY 0 0 240 437 1 1
SIRT3 PDK4 0 0 325 342 1 1
SIRT3 NSD1 0 0 108 223 1 1
SIRT3 MSH2 0 0 96 162 1 1
SIRT3 ESR1 0 0 391 414 1 2
SIRT3 LMNB1 0 0 201 229 1 1
SIRT3 ACADS 0 0 645 646 1 1
SIRT3 CHCHD3 0 0 92 177 1 1
SIRT3 SMEK1 0 0 195 228 1 1
SIRT3 SLC6A3 0 0 95 151 1 1
SIRT3 ELN 0 0 171 171 1 1
SIRT3 LRPPRC 0 0 181 181 1 2
SIRT3 FOXN2 0 0 0 166 1 1
SIRT3 CACUL1 0 0 0 155 1 1
SIRT3 NDUFA2 0 0 91 329 1 1
SIRT3 BRD8 0 0 0 191 1 1
SIRT3 PRKD1 0 0 210 210 1 1
SIRT3 HIST2H3A 0 0 0 185 1 1
SIRT3 CDK5RAP1 0 0 67 156 1 1
SIRT3 MAP1LC3B 0 0 314 371 1 2
SIRT3 TSG101 0 0 0 155 1 2
SIRT3 USP30 0 0 160 243 1 1
SIRT3 TET2 0 0 218 218 1 2
SIRT3 TERT 0 0 297 356 1 2
SIRT3 HADHB 0 0 147 229 1 1
SIRT3 FN1 0 0 219 219 1 2
SIRT3 MT-CYB 0 0 286 290 1 1
SIRT3 MT-CO1 0 0 322 373 1 1
SIRT3 TBP 0 0 181 204 1 1
SIRT3 AMDHD2 0 0 74 168 1 1
SIRT3 MPST 0 0 103 174 1 1
SIRT3 COQ3 0 0 48 254 1 1
SIRT3 MMP13 0 0 170 171 1 2
SIRT3 SETDB2 0 0 90 208 1 1
SIRT3 HIST1H2BE 0 0 0 170 1 1
SIRT3 ATP5G1 0 0 140 280 1 1
SIRT3 ULK1 0 0 325 352 1 2
SIRT3 SETD2 0 0 175 302 1 1
SIRT3 RAD52 0 0 107 220 1 1
SIRT3 PHF23 0 0 0 166 1 1
SIRT3 FOXK1 0 0 0 166 1 1
SIRT3 APOO 0 0 0 171 1 1
SIRT3 MLST8 0 0 228 249 1 1
SIRT3 HIST1H3E 0 0 76 215 1 1
SIRT3 KDM2B 0 0 161 291 1 1
SIRT3 PDHX 0 0 213 296 1 1
SIRT3 KRAS 0 0 203 230 1 2
SIRT3 MECR 0 0 0 314 1 1
SIRT3 GPBAR1 0 0 155 154 1 1
SIRT3 FOXD1 0 0 0 166 1 1
SIRT3 JMJD6 0 0 162 183 1 1
SIRT3 OR5W2 0 0 0 187 1 1
SIRT3 FASLG 0 0 152 151 1 1
SIRT3 KDM6B 0 0 286 406 1 1
SIRT3 TRDMT1 0 0 206 263 1 1
SIRT3 ANKRD32 0 0 0 255 1 1
SIRT3 WDR59 0 0 0 197 1 1
SIRT3 DUSP27 0 0 0 156 1 1
SIRT3 PON1 0 0 195 195 1 1
SIRT3 TMEM11 0 0 0 154 1 1
SIRT3 FOXN1 0 0 0 166 1 1
SIRT3 QPRT 0 0 391 455 1 1
SIRT3 DEPTOR 0 0 155 154 1 2
SIRT3 ACADVL 487 0 358 665 1 1
SIRT3 GFM2 0 0 0 212 1 1
SIRT3 CAPG 0 0 0 166 1 1
SIRT3 FAM219A 0 0 120 257 1 1
SIRT3 NUDT19 0 0 44 170 1 1
SIRT3 LPIN1 0 0 179 288 1 2
SIRT3 FOXC1 0 0 0 166 1 1
SIRT3 ACOX3 0 0 54 155 1 1
SIRT3 RBBP8 0 0 219 219 1 1
SIRT3 ZC3HAV1 0 0 240 239 1 1
SIRT3 FBXL19 0 0 0 268 1 1
SIRT3 ABCB1 0 0 95 166 1 2
SIRT3 NAP1L4 0 0 0 204 1 1
SIRT3 BECN1 0 0 459 489 1 2
SIRT3 MAPT 0 0 324 323 1 2
SIRT3 HIST1H2BB 0 0 0 170 1 1
SIRT3 ABCC1 0 0 57 158 1 1
SIRT3 COX4I2 0 0 321 321 1 1
SIRT3 OLR1 0 0 93 234 1 2
SIRT3 FMO5 0 0 57 163 1 1
SIRT3 IL2 0 0 155 154 1 1
SIRT3 NCAPD2 94 0 0 441 1 1
SIRT3 DUSP1 0 0 150 272 1 1
SIRT3 ACADL 0 0 720 720 1 1
SIRT3 MED7 0 0 0 155 1 1
SIRT3 MACROD1 0 0 409 563 1 1
SIRT3 MLH1 0 0 137 179 1 1
SIRT3 HIST1H4G 0 0 0 194 1 1
SIRT3 KIAA2013 0 0 0 181 1 1
SIRT3 ACE 0 0 301 301 1 1
SIRT3 POLR3A 0 0 0 200 1 1
SIRT3 ABCA7 0 0 74 160 1 1
SIRT3 REN 0 0 334 368 1 1
SIRT3 TNFRSF10B 0 0 155 154 1 2
SIRT3 HDAC11 0 0 801 851 1 1
SIRT3 CYBB 0 0 325 325 1 2
SIRT3 RAD21 0 0 94 222 1 1
SIRT3 OMA1 0 0 250 268 1 1
SIRT3 SMARCA1 0 0 183 229 1 1
SIRT3 HIST1H2BG 0 0 0 170 1 1
SIRT3 EGLN1 0 0 279 294 1 1
SIRT3 HCRT 0 0 215 215 1 1
SIRT3 PARS2 0 0 0 197 1 1
SIRT3 REL 0 0 142 166 1 2
SIRT3 NLRP3 0 0 362 362 1 2
SIRT3 BRCA2 0 0 155 174 1 1
SIRT3 ATXN7L1 0 0 0 166 1 1
SIRT3 PARG 0 0 421 437 1 1
SIRT3 HDAC9 0 0 636 750 1 1
SIRT3 ENPP1 0 650 67 662 1 1
SIRT3 MYH7 0 0 108 163 1 1
SIRT3 MLLT3 0 0 150 191 1 1
SIRT3 HADH 0 0 283 300 1 1
SIRT3 PTGS2 0 0 298 298 1 2
SIRT3 MT-ND2 0 0 213 273 1 1
SIRT3 CASP3 0 0 504 504 1 2
SIRT3 ATAT1 0 0 261 274 1 1
SIRT3 TXNRD1 0 0 155 223 1 1
SIRT3 CEBPB 0 0 280 297 1 2
SIRT3 NRM 0 0 0 169 1 1
SIRT3 PIK3CD 0 0 45 161 1 1
SIRT3 TXNRD2 0 0 210 246 1 1
SIRT3 BDH1 0 0 234 258 1 1
SIRT3 ERCC5 0 0 0 168 1 1
SIRT3 ACO1 0 0 113 152 1 1
SIRT3 PPP6C 0 0 101 171 1 1
SIRT3 CDKN2A 0 0 413 453 1 2
SIRT3 NUDT9 0 0 181 223 1 1
SIRT3 GPX8 0 0 90 265 1 1
SIRT3 GSK3B 0 0 294 313 1 2
SIRT3 DUSP2 0 0 0 156 1 1
SIRT3 UNC119 0 0 74 167 1 1
SIRT3 ZFP90 0 0 0 265 1 1
SIRT3 MRPS18B 0 0 0 171 1 1
SIRT3 LYPLA1 0 0 0 181 1 1
SIRT3 PSEN2 0 0 181 181 1 1
SIRT3 PRMT1 0 0 233 263 1 1
SIRT3 SCO2 0 0 283 318 1 1
SIRT3 NOTCH1 0 0 299 310 1 2
SIRT3 GLYATL1 0 0 556 556 1 1
SIRT3 SMARCAD1 0 0 0 231 1 1
SIRT3 CISD1 0 0 164 239 1 1
SIRT3 MT-CO3 0 0 95 156 1 1
SIRT3 POTEF 0 0 154 208 1 1
SIRT3 KAT7 0 0 211 364 1 1
SIRT3 UBAP1L 0 0 157 156 1 1
SIRT3 MPO 0 0 160 159 1 2
SIRT3 UCP2 0 0 601 635 1 2
SIRT3 IL6 0 0 468 468 1 2
SIRT3 NFYB 0 0 51 217 1 1
SIRT3 FOXO6 0 900 340 947 1 1
SIRT3 NAP1L1 0 0 0 204 1 1
SIRT3 CBX3 0 0 81 223 1 1
SIRT3 BRD2 0 0 210 333 1 1
SIRT3 H3F3A 0 0 48 207 1 1
SIRT3 SIRT5 270 0 857 649 1 1
SIRT3 GCK 0 0 262 348 1 1
SIRT3 SMAD9 0 0 75 209 1 1
SIRT3 HIF1A 0 0 611 616 1 2
SIRT3 EDN1 0 0 241 240 1 1
SIRT3 IL1B 0 0 457 457 1 2
SIRT3 ASB18 0 0 92 236 1 1
SIRT3 SETD5 0 0 0 182 1 1
SIRT3 SP1 0 0 195 209 1 2
SIRT3 BTD 0 0 107 176 1 1
SIRT3 GABPA 0 0 139 157 1 1
SIRT3 NUDT15 0 0 0 177 1 1
SIRT3 NDUFS4 0 0 325 487 1 1
SIRT3 CDK2 0 0 212 246 1 2
SIRT3 MAP1LC3A 0 0 193 373 1 2
SIRT3 LIPE 0 0 218 218 1 1
SIRT3 NAPRT 0 0 504 608 1 1
SIRT3 UPK2 0 0 0 166 1 1
SIRT3 SHMT2 0 0 166 209 1 1
SIRT3 PLA2G4A 0 0 111 184 1 1
SIRT3 ACSL5 0 0 660 665 1 1
SIRT3 UQCRB 0 0 70 242 1 1
SIRT3 XPO1 0 0 142 173 1 1
SIRT3 PRKAG1 0 0 90 194 1 1
SIRT3 FOXD4L4 0 0 0 166 1 1
SIRT3 ME1 0 0 134 175 1 1
SIRT3 ACSS2 0 900 595 960 1 1
SIRT3 SLC25A20 0 0 193 309 1 1
SIRT3 FOXD4L5 0 0 0 166 1 1
SIRT3 TFB1M 0 0 208 236 1 1
SIRT3 SH2D1B 0 0 244 273 1 1
SIRT3 DNMT3B 0 0 347 347 1 1
SIRT3 SLC5A4 0 0 162 163 1 1
SIRT3 DNMT3A 0 0 366 366 1 2
SIRT3 XPA 0 0 241 269 1 1
SIRT3 BCL2L1 0 0 374 404 1 2
SIRT3 RECQL 0 0 58 215 1 1
SIRT3 NMNAT1 0 650 566 867 1 1
SIRT3 TLR4 0 0 322 333 1 2
SIRT3 SMAD2 0 0 211 325 1 2
SIRT3 SLC25A11 0 0 71 251 1 1
SIRT3 NDUFV2 0 0 117 253 1 1
SIRT3 LARS2 0 0 447 459 1 1
SIRT3 ATG14 0 0 140 158 1 2
SIRT3 GABARAPL2 0 0 324 380 1 2
SIRT3 ATRX 0 0 108 158 1 1
SIRT3 NOS2 0 0 151 170 1 2
SIRT3 DUSP15 0 0 0 156 1 1
SIRT3 LONP1 0 0 320 417 1 1
SIRT3 EP400 0 0 51 192 1 1
SIRT3 PLGRKT 0 0 0 183 1 1
SIRT3 TENC1 0 0 0 156 1 1
SIRT3 RAD50 0 0 67 198 1 1
SIRT3 MINOS1 0 0 0 303 1 1
SIRT3 BCKDHA 0 0 112 178 1 1
SIRT3 HSPA1L 94 0 55 222 1 1
SIRT3 JHDM3C 0 0 141 154 1 1
SIRT3 NIT1 130 0 134 267 1 1
SIRT3 COX5A 0 0 120 190 1 1
SIRT3 PDHA2 0 0 0 151 1 1
SIRT3 FGF21 0 0 409 408 1 2
SIRT3 CCNB1 0 0 188 202 1 1
SIRT3 ANXA5 0 0 314 320 1 2
SIRT3 CS 270 0 459 617 1 1
SIRT3 HSPD1 489 0 187 579 1 1
SIRT3 MBD1 0 0 127 159 1 1
SIRT3 PTGES2 0 0 0 169 1 1
SIRT3 MGMT 0 0 123 215 1 2
SIRT3 HES1 0 0 76 165 1 2
SIRT3 FBXO32 0 0 203 203 1 2
SIRT3 TMEM199 0 0 0 171 1 1
SIRT3 WHSC1 0 0 157 266 1 1
SIRT3 FOXM1 0 0 204 307 1 1
SIRT3 PDP2 0 0 101 188 1 1
SIRT3 PRDX5 0 0 150 202 1 1
SIRT3 KLF3 0 0 136 323 1 1
SIRT3 EPO 0 0 235 235 1 2
SIRT3 ATF5 0 0 202 202 1 1
SIRT3 PLK1 0 0 108 181 1 2
SIRT3 MEF2D 0 0 161 176 1 2
SIRT3 SMAD4 0 0 181 261 1 2
SIRT3 COX7A2 0 0 92 614 1 1
SIRT3 MYCN 0 0 155 186 1 1
SIRT3 HDAC3 0 0 556 729 1 2
SIRT3 HIST1H4L 0 0 560 643 1 1
SIRT3 HDAC5 0 0 450 626 1 1
SIRT3 EIF5B 0 0 171 216 1 1
SIRT3 TDO2 0 0 254 284 1 1
SIRT3 HIPK4 0 0 0 184 1 1
SIRT3 NDUFB7 0 0 0 309 1 1
SIRT3 HSD17B10 270 0 88 326 1 1
SIRT3 PARD3 0 0 0 248 1 1
SIRT3 PARK7 0 0 276 365 1 2
SIRT3 ACSL1 0 0 180 192 1 1
SIRT3 FBXL3 0 0 134 163 1 1
SIRT3 FXN 0 0 392 502 1 1
SIRT3 CEP97 0 0 0 189 1 1
SIRT3 CAB39 0 0 113 166 1 1
SIRT3 MECP2 0 0 283 322 1 1
SIRT3 PGAM5 0 0 150 169 1 1
SIRT3 NFE2L2 0 0 469 499 1 2
SIRT3 EHMT2 0 0 321 409 1 2
SIRT3 ENSG00000272772 0 0 0 197 1 1
SIRT3 CIDEA 0 0 170 169 1 1
SIRT3 ACAD9 270 0 134 365 1 1
SIRT3 AKT2 0 0 430 459 1 2
SIRT3 BRD9 0 0 143 182 1 1
SIRT3 NPY 0 0 213 213 1 1
SIRT3 PFKM 0 0 262 265 1 1
SIRT3 CYB5A 0 0 89 167 1 1
SIRT3 HIST1H2BM 0 0 0 170 1 1
SIRT3 PPIF 0 0 767 771 1 1
SIRT3 MAP2K1 0 0 135 150 1 1
SIRT3 ODC1 0 0 97 163 1 1
SIRT3 MFF 0 0 340 340 1 1
SIRT3 MYC 0 0 661 666 1 2
SIRT3 MRPS11 0 0 61 191 1 1
SIRT3 PDK1 179 0 323 440 1 2
SIRT3 HIPK1 0 0 0 197 1 1
SIRT3 STK32B 0 0 0 157 1 1
SIRT3 PPIG 0 0 161 174 1 1
SIRT3 APEX1 0 0 235 298 1 1
SIRT3 SLC6A4 0 0 66 183 1 1
SIRT3 IL18 0 0 262 262 1 2
SIRT3 TRAPPC9 0 0 0 173 1 1
SIRT3 PARP12 0 0 166 165 1 1
SIRT3 RPS26 0 0 0 188 1 1
SIRT3 SDHC 0 0 228 453 1 1
SIRT3 IGF1R 0 0 260 260 1 2
SIRT3 H1F0 0 0 323 347 1 1
SIRT3 HIST1H2BD 0 0 0 170 1 1
SIRT3 ANKRD28 0 0 0 192 1 1
SIRT3 GLS 0 0 246 249 1 2
SIRT3 ATP5G3 0 0 95 440 1 1
SIRT3 PIK3CA 0 0 113 198 1 2
SIRT3 CAMKMT 0 0 170 169 1 1
SIRT3 CDYL 0 0 112 249 1 1
SIRT3 SBNO2 0 0 0 156 1 1
SIRT3 TOP3A 0 0 73 153 1 1
SIRT3 ACACA 0 0 230 244 1 1
SIRT3 KARS 0 0 397 397 1 1
SIRT3 SETD8 0 0 161 270 1 1
SIRT3 MRPL46 0 0 67 242 1 1
SIRT3 KDM7A 0 0 95 262 1 1
SIRT3 HSCB 270 0 0 309 1 1
SIRT3 FOXE3 0 0 0 166 1 1
SIRT3 CYBA 0 0 172 171 1 1
SIRT3 GSTK1 0 0 122 202 1 1
SIRT3 CAMKK2 0 0 202 242 1 2
SIRT3 BAZ2A 0 0 138 273 1 1
SIRT3 NDUFB1 0 0 0 183 1 1
SIRT3 PDXP 0 0 0 239 1 1
SIRT3 MTAP 0 0 90 178 1 1
SIRT3 PSMD13 0 0 392 436 1 1
SIRT3 ERN1 0 0 203 203 1 2
SIRT3 XRCC6 270 0 772 853 1 1
SIRT3 ENPP3 0 650 0 653 1 1
SIRT3 PYCR1 270 0 90 323 1 1
SIRT3 GATA3 0 0 389 388 1 1
SIRT3 AGO2 0 0 92 154 1 2
SIRT3 ODF3 0 0 212 212 1 1
SIRT3 CD55 0 0 180 179 1 1
SIRT3 CPT2 0 0 245 415 1 1
SIRT3 MST1 0 0 81 194 1 2
SIRT3 VDAC2 0 0 230 271 1 1
SIRT3 EZH2 0 0 348 432 1 2
SIRT3 STAT3 0 0 551 551 1 2
SIRT3 TUBA4A 0 0 73 158 1 1
SIRT3 GART 0 0 0 255 1 1
SIRT3 PRKCE 0 0 436 436 1 1
SIRT3 FOXS1 0 0 0 166 1 1
SIRT3 SARM1 0 0 210 210 1 1
SIRT3 CDK4 0 0 213 247 1 2
SIRT3 HIST1H4I 0 0 560 643 1 1
SIRT3 LMNA 0 0 233 371 1 2
SIRT3 SLC2A2 0 0 181 205 1 1
SIRT3 EXO1 0 0 90 211 1 1
SIRT3 ACSL6 0 0 443 452 1 1
SIRT3 HK2 0 0 402 427 1 2
SIRT3 DDIT3 0 0 236 254 1 2
SIRT3 NME3 0 0 0 205 1 1
SIRT3 SLC25A4 0 0 138 279 1 1
SIRT3 MCAT 0 0 251 276 1 1
SIRT3 PPOX 0 0 49 269 1 1
SIRT3 YWHAG 0 0 50 195 1 1
SIRT3 HYOU1 0 0 60 181 1 1
SIRT3 HIST1H4E 0 0 560 643 1 1
SIRT3 KMT2B 0 0 123 237 1 1
SIRT3 CDK6 0 0 171 207 1 2
SIRT3 HDAC8 0 0 688 785 1 1
SIRT3 HMGCS2 0 0 596 603 1 1
SIRT3 NDUFA4 0 0 137 172 1 1
SIRT3 MLXIPL 0 0 293 308 1 1
SIRT3 BMP7 0 0 112 197 1 1
SIRT3 NR3C2 0 0 120 153 1 1
SIRT3 DPP4 0 0 143 275 1 1
SIRT3 BOLA2B 0 0 0 152 1 1
SIRT3 STK32A 0 0 0 157 1 1
SIRT3 NFIL3 0 0 136 162 1 1
SIRT3 LGALS4 0 0 162 161 1 1
SIRT3 FOXI3 0 0 0 166 1 1
SIRT3 H2AFX 0 0 267 305 1 1
SIRT3 IL1A 0 0 213 213 1 1
SIRT3 FECH 209 0 63 254 1 1
SIRT3 POLG 0 0 250 297 1 1
SIRT3 CUL5 0 0 0 160 1 1
SIRT3 DCTN1 0 0 46 168 1 1
SIRT3 ABCA1 0 0 213 255 1 2
SIRT3 BAG2 0 0 445 445 1 1
SIRT3 MCM4 0 0 0 219 1 1
SIRT3 LEPR 0 0 187 187 1 1
SIRT3 CASP8 0 0 249 248 1 2
SIRT3 SDHA 213 0 520 665 1 1
SIRT3 ADRB3 0 0 180 179 1 1
SIRT3 PGK1 0 0 210 238 1 2
SIRT3 KAT2A 0 0 603 700 1 1
SIRT3 DHDH 0 0 0 165 1 1
SIRT3 FAP 0 0 0 302 1 2
SIRT3 AACS 0 0 95 151 1 1
SIRT3 PIWIL4 0 0 155 154 1 1
SIRT3 PHF11 0 0 0 165 1 1
SIRT3 GPX5 0 0 0 206 1 1
SIRT3 LIG3 0 0 141 216 1 1
SIRT3 HIST2H3D 0 0 0 185 1 1
SIRT3 CHRAC1 0 0 0 164 1 1
SIRT3 TNK2 0 0 281 313 1 1
SIRT3 CASP9 0 0 323 323 1 2
SIRT3 HK1 0 0 257 294 1 1
SIRT3 NANOG 0 0 167 167 1 2
SIRT3 POMC 0 0 249 248 1 1
SIRT3 NMRK2 0 0 254 268 1 1
SIRT3 CHEK2 0 0 282 419 1 1
SIRT3 OGG1 0 0 391 443 1 1
SIRT3 CWC27 0 0 0 164 1 1
SIRT3 MAPK9 0 0 207 299 1 2
SIRT3 SMARCA5 0 0 295 334 1 1
SIRT3 AKR1B1 0 0 209 218 1 1
SIRT3 SETD7 0 0 316 404 1 1
SIRT3 COQ2 0 0 73 176 1 1
SIRT3 PRKAB2 0 0 90 213 1 1
SIRT3 GLUD2 0 900 0 913 1 1
SIRT3 NDUFB9 0 0 45 247 1 1
SIRT3 FASN 0 0 284 284 1 2
SIRT3 PER3 0 0 139 180 1 1
SIRT3 ACAD10 0 0 57 335 1 1
SIRT3 ATPAF2 0 0 95 251 1 1
SIRT3 ASB10 0 0 0 193 1 1
SIRT3 NDUFAB1 0 0 140 166 1 1
SIRT3 RPTOR 0 0 315 423 1 2
SIRT3 BPTF 0 0 94 336 1 1
SIRT3 HIF1AN 0 0 163 172 1 1
SIRT3 MRPS5 0 0 218 288 1 1
SIRT3 PIF1 0 0 60 166 1 1
SIRT3 MIEF1 0 0 170 187 1 1
SIRT3 SCIN 0 0 0 438 1 1
SIRT3 KLF5 0 0 137 152 1 2
SIRT3 TNS1 0 0 75 186 1 1
SIRT3 FOXI1 0 0 0 166 1 1
SIRT3 NDUFS5 0 0 0 321 1 1
SIRT3 SURF1 0 0 181 249 1 1
SIRT3 HSPA6 0 0 0 164 1 1
SIRT3 HIST2H3PS2 0 0 603 662 1 1
SIRT3 HNMT 0 0 310 309 1 1
SIRT3 CTGF 0 0 180 179 1 1
SIRT3 RPS6KB2 0 0 72 184 1 2
SIRT3 CPT1B 0 0 280 292 1 1
SIRT3 GLUD1 270 900 322 954 1 1
SIRT3 NR3C1 0 0 274 327 1 1
SIRT3 FKBP1A 0 0 157 189 1 2
SIRT3 MT-ND6 0 0 202 202 1 1
SIRT3 H2AFZ 0 0 182 224 1 1
SIRT3 ADIPOQ 0 0 459 459 1 2
SIRT3 RUVBL1 270 0 52 294 1 1
SIRT3 TMEM167B 0 0 0 256 1 1
SIRT3 GRB7 0 0 0 205 1 1
SIRT3 AURKB 0 0 125 229 1 1
SIRT3 ARG1 0 0 162 173 1 2
SIRT3 SKP2 486 0 270 609 1 2
SIRT3 PRKAB1 0 0 109 289 1 2
SIRT3 FOXP1 0 0 49 180 1 1
SIRT3 BCKDK 0 0 0 200 1 1
SIRT3 CUTC 0 0 74 260 1 1
SIRT3 CSTF3 0 0 0 157 1 1
SIRT3 DLL1 0 0 57 282 1 1
SIRT3 CYB5B 0 0 90 162 1 1
SIRT3 STYX 0 0 0 156 1 1
SIRT3 CD8A 0 0 180 179 1 1
SIRT3 FUNDC1 0 0 310 309 1 2
SIRT3 TFAM 0 0 618 658 1 2
SIRT3 FZR1 0 0 66 200 1 1
SIRT3 HIST2H3C 0 0 0 185 1 1
SIRT3 MMP2 0 0 217 218 1 2
SIRT3 CLPX 0 0 139 175 1 1
SIRT3 ATP5B 94 0 213 527 1 1
SIRT3 GRN 117 0 90 168 1 1
SIRT3 KDM4A 0 0 261 272 1 1
SIRT3 ELP3 0 0 175 377 1 1
SIRT3 TET3 0 0 175 175 1 1
SIRT3 NDUFA3 0 0 54 257 1 1
SIRT3 YWHAE 0 0 0 180 1 1
SIRT3 LAMP2 0 0 123 159 1 2
SIRT3 PRDX1 0 0 186 242 1 1
SIRT3 SMYD3 0 0 125 238 1 1
SIRT3 DUSP22 0 0 0 156 1 1
SIRT3 WDR5 0 0 139 163 1 1
SIRT3 TAZ 0 0 161 178 1 1
SIRT3 BCL2L11 0 0 347 347 1 2
SIRT3 TSC1 0 0 164 183 1 2
SIRT3 DLL4 0 0 107 182 1 1
SIRT3 TNKS 0 0 283 336 1 1
SIRT3 NRF1 0 0 517 517 1 2
SIRT3 BRD3 0 0 183 310 1 1
SIRT3 PHF13 0 0 0 166 1 1
SIRT3 KL 0 0 395 394 1 2
SIRT3 BCS1L 0 0 103 198 1 1
SIRT3 RHOT1 0 0 70 219 1 1
SIRT3 NNMT 0 900 457 943 1 1
SIRT3 CHEK1 0 0 208 274 1 2
SIRT3 SLC25A27 0 0 243 330 1 1
SIRT3 NADK2 0 900 113 909 1 1
SIRT3 SNCA 0 0 460 467 1 2
SIRT3 SLC16A3 0 0 206 206 1 1
SIRT3 AKT1S1 0 0 154 153 1 1
SIRT3 SCO1 0 0 94 210 1 1
SIRT3 CASP1 0 0 249 248 1 2
SIRT3 MALSU1 0 0 55 196 1 1
SIRT3 CAV1 0 0 169 169 1 2
SIRT3 SRF 0 0 181 196 1 1
SIRT3 SLC25A31 0 0 0 153 1 1
SIRT3 OGDH 0 0 181 272 1 1
SIRT3 HSPA1A 0 0 210 312 1 1
SIRT3 PER2 0 0 422 450 1 1
SIRT3 ULK2 0 0 136 153 1 2
SIRT3 PRPSAP2 0 0 0 151 1 1
SIRT3 CDC20 0 0 134 212 1 1
SIRT3 DNMT1 0 0 459 475 1 2
SIRT3 DLST 0 0 150 380 1 1
SIRT3 STUB1 0 0 233 264 1 2
SIRT3 CTTN 0 0 263 263 1 1
SIRT3 SPG7 0 0 164 256 1 1
SIRT3 SETD3 0 0 69 162 1 1
SIRT3 FOXG1 0 0 48 432 1 1
SIRT3 ASH1L 0 0 112 227 1 1
SIRT3 ACTB 0 0 505 536 1 2
SIRT3 AK2 0 0 45 156 1 1
SIRT3 FOXJ3 0 0 49 210 1 1
SIRT3 INS 0 0 668 668 1 2
SIRT3 HIST1H4J 0 0 560 643 1 1
SIRT3 PROM1 0 0 156 168 1 2
SIRT3 KMT2C 0 0 113 228 1 1
SIRT3 ANGPT1 0 0 134 154 1 1
SIRT3 MCEE 0 0 46 169 1 1
SIRT3 HSPE1 0 0 242 250 1 1
SIRT3 KEAP1 0 0 450 462 1 2
SIRT3 FBXW7 0 0 96 272 1 2
SIRT3 ACAA2 0 0 108 186 1 1
SIRT3 TMTC1 0 0 630 636 1 1
SIRT3 HPGDS 0 0 243 242 1 1
SIRT3 PNPLA2 0 0 281 298 1 2
SIRT3 SETDB1 0 0 194 298 1 1
SIRT3 TFEB 0 0 273 297 1 2
SIRT3 HADHA 0 0 243 286 1 1
SIRT3 DYRK2 0 0 0 189 1 1
SIRT3 SUV39H1 0 0 450 521 1 1
SIRT3 COX4I1 0 0 504 565 1 1
SIRT3 KDM1B 0 0 240 306 1 1
SIRT3 SETBP1 0 0 0 165 1 1
SIRT3 SETD1A 0 0 241 395 1 1
SIRT3 CEBPA 0 0 243 261 1 1
SIRT3 COQ7 0 0 122 263 1 1
SIRT3 HTRA2 0 0 233 337 1 1
SIRT3 WRN 0 0 370 476 1 1
SIRT3 ATP5S 0 0 45 546 1 1
SIRT3 METAP1D 130 0 0 150 1 1
SIRT3 TRPT1 0 0 112 184 1 1
SIRT3 ESR2 0 0 233 262 1 1
SIRT3 FEN1 0 0 93 213 1 1
SIRT3 ISOC2 0 0 0 289 1 1
SIRT3 PACRG 0 0 0 188 1 1
SIRT3 GABARAPL1 0 0 325 381 1 2
SIRT3 PDK2 270 0 112 360 1 1
SIRT3 FOXD3 0 0 0 166 1 1
SIRT3 ZEB1 0 0 431 431 1 2
SIRT3 SIRT7 0 0 784 486 1 2
SIRT3 MPC1 0 0 436 450 1 1
SIRT3 PARP1 0 0 710 717 1 2
SIRT3 RHOA 0 0 170 169 1 2
SIRT3 EIF4G1 0 0 73 172 1 2
SIRT3 CRTC2 0 0 341 341 1 1
SIRT3 HSPA8 0 0 212 313 1 2
SIRT3 INSR 0 0 112 176 1 1
SIRT3 GSR 0 0 394 406 1 1
SIRT3 NKRF 0 0 294 306 1 1
SIRT3 MTTP 0 0 155 156 1 1
SIRT3 SETMAR 0 0 0 165 1 1
SIRT3 GABPB1 0 0 266 311 1 1
SIRT3 PIWIL1 0 0 159 158 1 1
SIRT3 KDM1A 0 0 452 497 1 2
SIRT3 HIST1H2BL 0 0 0 170 1 1
SIRT3 TMLHE 0 0 0 179 1 1
SIRT3 TOMM40 0 0 155 183 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0003950 Molecular Function NAD+ ADP-ribosyltransferase activity NOT enables TAS
GO:0070403 Molecular Function NAD+ binding enables IBA
GO:1990404 Molecular Function NAD+-protein ADP-ribosyltransferase activity NOT enables TAS
GO:0017136 Molecular Function NAD-dependent histone deacetylase activity enables IBA
GO:0034979 Molecular Function NAD-dependent protein deacetylase activity enables ISS
GO:0034979 Molecular Function NAD-dependent protein deacetylase activity enables TAS
GO:0019899 Molecular Function enzyme binding enables IEA
GO:0005515 Molecular Function protein binding enables IPI
GO:0043565 Molecular Function sequence-specific DNA binding enables IDA
GO:0008270 Molecular Function zinc ion binding enables IDA
GO:0009060 Biological Process aerobic respiration involved_in IMP
GO:0006338 Biological Process chromatin remodeling involved_in IEA
GO:0070373 Biological Process negative regulation of ERK1 and ERK2 cascade involved_in IEA
GO:2000378 Biological Process negative regulation of reactive oxygen species metabolic process involved_in IEA
GO:0034983 Biological Process peptidyl-lysine deacetylation involved_in IMP
GO:0034983 Biological Process peptidyl-lysine deacetylation involved_in ISS
GO:1902553 Biological Process positive regulation of catalase activity involved_in IDA
GO:2000304 Biological Process positive regulation of ceramide biosynthetic process involved_in ISS
GO:0032024 Biological Process positive regulation of insulin secretion involved_in IEA
GO:1901671 Biological Process positive regulation of superoxide dismutase activity involved_in IDA
GO:0006476 Biological Process protein deacetylation involved_in IDA
GO:0005759 Cellular Component mitochondrial matrix located_in IDA
GO:0005759 Cellular Component mitochondrial matrix located_in TAS
GO:0005739 Cellular Component mitochondrion located_in IDA
GO:0005654 Cellular Component nucleoplasm located_in TAS
GO:0005634 Cellular Component nucleus is_active_in IBA
GO:0032991 Cellular Component protein-containing complex part_of IDA
Pathways
Name DB ID
Mitochondrial biogenesis Reactome R-HSA-1592230
Organelle biogenesis and maintenance Reactome R-HSA-1852241
Generic Transcription Pathway Reactome R-HSA-212436
Transcriptional activation of mitochondrial biogenesis Reactome R-HSA-2151201
RNA Polymerase II Transcription Reactome R-HSA-73857
Gene expression (Transcription) Reactome R-HSA-74160
FOXO-mediated transcription Reactome R-HSA-9614085
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes Reactome R-HSA-9615017
Regulation of FOXO transcriptional activity by acetylation Reactome R-HSA-9617629
NAD+ metabolism (WP3644) WikiPathways WP3644_r118983
NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence (WP5046) WikiPathways WP5046_r118987
NAD metabolism, sirtuins and aging (WP3630) WikiPathways WP3630_r121716
NAD+ biosynthetic pathways (WP3645) WikiPathways WP3645_r123910
Energy metabolism (WP1541) WikiPathways WP1541_r117711
Transcripts
Accession Version MolecularType Name NCBI Comments
NR_163391 1 miscRNA transcript variant 22 NC_000011 Reference
NR_163387 1 miscRNA transcript variant 18 NC_000011 Reference
NR_163389 1 miscRNA transcript variant 20 NC_000011 Reference
NR_163388 1 miscRNA transcript variant 19 NC_000011 Reference
NR_163390 1 miscRNA transcript variant 21 NC_000011 Reference
NR_163392 1 miscRNA transcript variant 23 NC_000011 Reference
NR_163386 1 miscRNA transcript variant 17 NC_000011 Reference
NR_163393 1 miscRNA transcript variant 24 NC_000011 Reference
NR_163397 1 miscRNA transcript variant 28 NC_000011 Reference
NR_163395 1 miscRNA transcript variant 26 NC_000011 Reference
NR_163400 1 miscRNA transcript variant 31 NC_000011 Reference
NR_163394 1 miscRNA transcript variant 25 NC_000011 Reference
NR_163398 1 miscRNA transcript variant 29 NC_000011 Reference
NR_163402 1 miscRNA transcript variant 33 NC_000011 Reference
NR_163399 1 miscRNA transcript variant 30 NC_000011 Reference
NR_163396 1 miscRNA transcript variant 27 NC_000011 Reference
NR_163401 1 miscRNA transcript variant 32 NC_000011 Reference
XR_007062467 1 miscRNA transcript variant X1 NC_000011 Reference
NM_001370324 1 mRNA transcript variant 15 NC_000011 Reference
NM_001370320 1 mRNA transcript variant 11 NC_000011 Reference
NM_001370319 1 mRNA transcript variant 10 NC_000011 Reference
NM_001370317 1 mRNA transcript variant 8 NC_000011 Reference
NM_001370322 1 mRNA transcript variant 13 NC_000011 Reference
NM_001370318 1 mRNA transcript variant 9 NC_000011 Reference
NM_001370321 1 mRNA transcript variant 12 NC_000011 Reference
XM_047426677 1 mRNA transcript variant X5 NC_000011 Reference
XM_017017431 2 mRNA transcript variant X4 NC_000011 Reference
NM_001370316 1 mRNA transcript variant 7 NC_000011 Reference
NM_001370315 1 mRNA transcript variant 6 NC_000011 Reference
NM_001370325 1 mRNA transcript variant 16 NC_000011 Reference
NM_001017524 3 mRNA transcript variant 2 NC_000011 Reference
NM_001370323 1 mRNA transcript variant 14 NC_000011 Reference
NM_001370312 1 mRNA transcript variant 4 NC_000011 Reference
NM_001370314 1 mRNA transcript variant 5 NC_000011 Reference
NM_012239 6 mRNA transcript variant 1 NC_000011 Reference
NM_001370310 1 mRNA transcript variant 3 NC_000011 Reference
XM_011519957 3 mRNA transcript variant X2 NC_000011 Reference
XM_011519956 3 mRNA transcript variant X3 NC_000011 Reference