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BACE1

beta-secretase 1
General Information
Name beta-secretase 1
Alias
  • beta-secretase 1
  • APP beta-secretase
  • asp 2
  • aspartyl protease 2
  • beta-site APP cleaving enzyme 1
  • beta-site APP-cleaving enzyme
  • beta-site amyloid beta A4 precursor protein-cleaving enzyme
  • memapsin-2
  • membrane-associated aspartic protease 2
  • transmembrane aspartic proteinase Asp2
Gene_family Peptidase family A1
organism Homo sapiens
entrez_id 23621
location 11q23.3
transcript_count 7
exon_count 11
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients. [provided by RefSeq, Nov 2015]
    Stringdb Beta-secretase 1; Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase; Belongs to the peptidase A1 family
    nextProt Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase (PubMed:10656250, PubMed:10677483, PubMed:20354142). Cleaves CHL1 (By similarity).
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
BACE1 BioGRID SCGB2A1 GeneID BioGRID Affinity Capture-MS
BACE1 BioGRID KLRC3 GeneID BioGRID Affinity Capture-MS
BACE1 BioGRID KLRC1 GeneID BioGRID Affinity Capture-MS
BACE1 BioGRID SCGB1D4 GeneID BioGRID Affinity Capture-MS
BACE1 BioGRID EDEM1 GeneID BioGRID Affinity Capture-Western
BACE1 BioGRID APP GeneID BioGRID Affinity Capture-Western; Biochemical Activity
BACE1 BioGRID NGFR GeneID BioGRID Affinity Capture-Western
BACE1 BioGRID ADRB2 GeneID BioGRID Two-hybrid
BACE1 BioGRID RTN4 GeneID BioGRID Affinity Capture-Western
BACE1 BioGRID RTN3 GeneID BioGRID Affinity Capture-Western
BACE1 BioGRID KCNC4 GeneID BioGRID Affinity Capture-Western
BACE1 BioGRID HYOU1 GeneID BioGRID Affinity Capture-Western; FRET
BACE1 BioGRID TMX1 GeneID BioGRID Affinity Capture-Western
BACE1 BioGRID KCNQ1 GeneID BioGRID Affinity Capture-Western
BACE1 BioGRID SORT1 GeneID BioGRID Affinity Capture-Western
BACE1 BioGRID GGA1 GeneID BioGRID Affinity Capture-Western; Co-crystal Structure; FRET; Reconstituted Complex
BACE1 BioGRID GGA3 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
BACE1 BioGRID GGA2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
BACE1 BioGRID USP8 GeneID BioGRID Biochemical Activity
BACE1 BioGRID STUB1 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
BACE1 BioGRID MMP2 GeneID BioGRID Co-localization
BACE1 BioGRID CSNK1D GeneID BioGRID Co-localization
BACE1 BioGRID NXF1 GeneID BioGRID Affinity Capture-RNA
BACE1 BioGRID MOV10 GeneID BioGRID Affinity Capture-RNA
BACE1 BioGRID COPS5 GeneID BioGRID Affinity Capture-Western
BACE1 BioGRID BRI3 GeneID BioGRID Affinity Capture-Western
BACE1 BioGRID RANBP9 GeneID BioGRID Affinity Capture-Western
BACE1 BioGRID PCSK9 GeneID BioGRID Biochemical Activity; Reconstituted Complex
BACE1 BioGRID FBXO2 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
BACE1 Protein CMPK1 GeneID HPRD
BACE1 Protein ITM2C GeneID HPRD
BACE1 Protein BRI3 GeneID HPRD
BACE1 Protein KHSRP GeneID HPRD
BACE1 Protein GGA2 GeneID HPRD
BACE1 Protein PLSCR1 GeneID HPRD
BACE1 Protein NCSTN GeneID HPRD
BACE1 Protein RANBP9 GeneID HPRD
BACE1 Protein PDIA3 GeneID HPRD
BACE1 Protein CSNK1D GeneID HPRD
BACE1 Protein SELPLG GeneID HPRD
BACE1 Protein ATP1B1 GeneID HPRD
BACE1 Protein PSAP GeneID HPRD
BACE1 Protein FURIN GeneID HPRD
BACE1 Protein MMP2 GeneID HPRD
BACE1 Protein LRP1 GeneID HPRD
BACE1 Protein APP GeneID HPRD
BACE1 Protein PSEN1 GeneID HPRD
BACE1 BioGRID NCSTN GeneID BioGRID Reconstituted Complex
BACE1 Protein ATP1B1 GeneID BIND BACE1 interacts with ATP1B1 (Na/K-ATPase, beta-subunit). This interaction was modelled on a demonstrated interaction between mouse BACE1 and human Na/K-ATPase, beta-subunit.
BACE1 Protein PSAP GeneID BIND BACE1 interacts with PSAP (prosaposin). This interaction was modelled on a demonstrated interaction between mouse BACE1 and human prosaposin.
BACE1 Protein PDIA3 GeneID BIND BACE1 interacts with PDIA3 (ERp60). This interaction was modelled on a demonstrated interaction between mouse BACE1 and human PDIA3.
BACE1 Protein CMPK1 GeneID BIND BACE1 interacts with UMP-CMPK. This interaction was modelled on a demonstrated interaction between mouse BACE1 and human UMP-CMPK.
BACE1 Protein RANBP9 GeneID BIND BACE1 interacts with RANBP9 (RANBPM). This interaction was modelled on a demonstrated interaction between mouse BACE1 and human RANBPM.
BACE1 Protein KHSRP GeneID BIND BACE1 interacts with KHSRP. This interaction was modelled on a demonstrated interaction between mouse BACE1 and human KHSRP.
BACE1 Protein NCSTN GeneID BIND Nicastrin interacts with BACE1.
BACE1 Protein ITM2C GeneID BIND BACE1 interacts with ITM2C (BRI3).
StringDB
A B experiments database textmining combined score hadb nhadb
BACE1 L1CAM 0 0 180 260 1 1
BACE1 GABRB2 0 0 0 164 1 1
BACE1 HIST1H4F 0 0 134 166 1 1
BACE1 XPNPEP1 0 0 99 170 1 1
BACE1 MYLK2 305 0 66 342 1 1
BACE1 PSMB4 0 0 0 155 1 1
BACE1 RAD23A 0 0 0 178 1 1
BACE1 GLA 0 0 66 164 1 2
BACE1 MTOR 0 0 324 350 1 2
BACE1 KCNH1 0 0 60 151 1 1
BACE1 SRSF9 0 0 0 150 1 1
BACE1 GNA13 0 0 0 177 1 1
BACE1 TCF20 0 0 218 239 1 1
BACE1 NBPF15 0 0 380 380 1 1
BACE1 CTRL 0 0 204 204 1 2
BACE1 MOG 0 0 149 188 1 1
BACE1 ETS2 0 0 134 171 1 1
BACE1 SMN1 0 0 170 169 1 1
BACE1 PIK3C3 0 0 124 164 1 2
BACE1 MPZ 0 0 117 177 1 1
BACE1 OCLN 0 0 160 159 1 1
BACE1 PLEK 0 0 95 260 1 1
BACE1 KCNMA1 0 0 112 201 1 1
BACE1 SYVN1 0 0 134 204 1 1
BACE1 SCPEP1 0 0 0 347 1 1
BACE1 STAT1 0 0 218 218 1 2
BACE1 ELAVL3 0 0 260 276 1 1
BACE1 RAB5A 0 0 451 471 1 2
BACE1 F11 0 0 309 309 1 1
BACE1 SMPD3 0 0 241 240 1 1
BACE1 RTN4RL1 0 0 120 159 1 1
BACE1 BAG3 0 0 88 156 1 2
BACE1 BBS1 0 0 62 195 1 1
BACE1 PPIAL4H 0 0 0 167 1 1
BACE1 ATXN1 0 0 294 304 1 1
BACE1 CTSL 0 0 195 384 1 2
BACE1 TTC31 0 0 0 152 1 1
BACE1 POLR2C 0 0 0 310 1 1
BACE1 SLC1A7 0 0 124 172 1 1
BACE1 NDRG1 0 0 180 180 1 1
BACE1 METTL1 0 0 0 150 1 1
BACE1 CXCL8 0 0 195 195 1 2
BACE1 MFN2 0 0 241 313 1 2
BACE1 APP 871 900 990 999 1 2
BACE1 EGR1 0 0 181 252 1 2
BACE1 SPRN 0 0 155 161 1 1
BACE1 CTNNB1 0 0 284 284 1 2
BACE1 HRAS 0 0 108 192 1 2
BACE1 CACNA1C 0 0 134 190 1 1
BACE1 IKBKE 0 0 0 175 1 1
BACE1 ARC 0 0 257 256 1 2
BACE1 DNM3 0 0 54 172 1 1
BACE1 CASP6 0 0 397 407 1 1
BACE1 KISS1 0 0 45 191 1 1
BACE1 GSTM3 0 0 0 151 1 1
BACE1 PIGP 0 0 0 189 1 1
BACE1 LGALS3BP 0 0 219 219 1 1
BACE1 EVPL 0 0 0 171 1 1
BACE1 GAPDH 0 0 501 528 1 2
BACE1 ENO1 0 0 81 199 1 1
BACE1 ENSG00000258466 0 0 0 158 1 1
BACE1 CX3CL1 0 0 157 175 1 1
BACE1 MAP2K7 0 0 181 181 1 1
BACE1 SPDEF 0 0 0 159 1 1
BACE1 ABL1 0 0 125 163 1 1
BACE1 PTBP1 0 0 236 242 1 2
BACE1 FKBP8 0 0 74 239 1 1
BACE1 ARL5B 0 0 154 288 1 1
BACE1 GPR3 0 0 261 261 1 1
BACE1 MOGS 0 0 49 205 1 1
BACE1 KCNB1 0 0 97 176 1 2
BACE1 CREBBP 0 0 167 180 1 1
BACE1 PRSS16 0 0 0 159 1 1
BACE1 TMEM30A 0 0 125 337 1 1
BACE1 NSG1 0 0 188 205 1 1
BACE1 DGCR8 0 0 210 210 1 1
BACE1 DDO 0 0 0 151 1 1
BACE1 PPID 0 0 138 220 1 1
BACE1 CADPS2 0 0 0 236 1 1
BACE1 FRAS1 0 0 0 334 1 1
BACE1 RSPO2 0 0 0 328 1 1
BACE1 CREB1 0 0 517 527 1 2
BACE1 GZMM 0 0 954 954 1 1
BACE1 CLTCL1 0 0 0 273 1 1
BACE1 NRG2 0 0 307 330 1 1
BACE1 NPEPPS 0 0 107 181 1 1
BACE1 KCNE1 0 0 169 174 1 1
BACE1 CNTN1 0 0 107 201 1 1
BACE1 CA2 0 0 155 173 1 1
BACE1 COL25A1 0 0 540 550 1 1
BACE1 PSAP 213 0 62 437 1 1
BACE1 SIRT2 0 0 282 319 1 2
BACE1 SERPINI1 0 0 141 163 1 1
BACE1 GRIK2 0 0 97 162 1 1
BACE1 CTSE 0 0 434 211 1 1
BACE1 LRP1B 0 0 157 206 1 1
BACE1 SLC2A3 0 0 194 217 1 1
BACE1 C9orf72 0 0 234 234 1 2
BACE1 SOAT1 0 0 306 338 1 1
BACE1 LRP5 0 0 96 254 1 1
BACE1 GOLPH3 0 0 154 219 1 1
BACE1 PPP1R1B 0 0 134 153 1 1
BACE1 SCN3B 0 0 142 195 1 1
BACE1 PAPPA 0 0 66 150 1 1
BACE1 B4GALNT1 0 0 101 168 1 1
BACE1 OPA1 0 0 277 330 1 2
BACE1 RTN4RL2 0 0 158 178 1 1
BACE1 AQP1 0 0 108 169 1 1
BACE1 SYNJ1 0 0 183 183 1 1
BACE1 CYB5D1 0 0 0 191 1 1
BACE1 PARK2 0 0 334 334 1 1
BACE1 BRI3 270 0 0 270 1 1
BACE1 LGMN 0 0 144 258 1 1
BACE1 SLC1A3 0 0 166 191 1 1
BACE1 ADAM10 312 0 825 906 1 1
BACE1 LRP3 0 0 208 311 1 1
BACE1 PPARGC1A 0 0 372 372 1 2
BACE1 ADAM30 0 0 150 208 1 1
BACE1 FA2H 0 0 48 197 1 1
BACE1 NLGN2 0 0 388 414 1 1
BACE1 GNAQ 0 0 97 198 1 1
BACE1 ADORA1 0 0 164 194 1 1
BACE1 LRP11 0 0 155 179 1 1
BACE1 GLIPR2 0 0 170 221 1 2
BACE1 SCN2A 0 0 301 372 1 1
BACE1 GPX7 0 0 0 165 1 1
BACE1 P4HB 305 0 459 633 1 2
BACE1 SCGB1D4 273 0 0 278 1 1
BACE1 ENSG00000261832 0 0 103 186 1 1
BACE1 PIM1 0 0 0 169 1 1
BACE1 LRP5L 0 0 0 209 1 1
BACE1 TPMT 0 0 593 593 1 1
BACE1 SHC3 0 0 167 333 1 1
BACE1 GNAT1 0 0 0 177 1 1
BACE1 ZDHHC15 0 0 204 257 1 1
BACE1 APAF1 0 0 96 154 1 2
BACE1 HDAC6 0 0 140 311 1 2
BACE1 CDH2 0 0 235 281 1 1
BACE1 PUF60 0 0 0 206 1 1
BACE1 JAK2 0 0 162 195 1 2
BACE1 REEP2 0 0 70 193 1 1
BACE1 NLGN1 0 0 261 302 1 1
BACE1 CALM3 0 0 60 169 1 1
BACE1 CTSW 0 0 0 246 1 1
BACE1 CLU 0 0 502 520 1 2
BACE1 MCOLN1 0 0 109 175 1 2
BACE1 SPTLC1 0 0 165 186 1 1
BACE1 NQO2 0 0 322 321 1 1
BACE1 PCSK5 0 0 95 366 1 1
BACE1 GDNF 0 0 285 284 1 2
BACE1 CPVL 0 0 0 393 1 1
BACE1 HNRNPH2 0 0 139 198 1 1
BACE1 EIF2AK4 0 0 282 299 1 2
BACE1 EPS15 0 0 151 174 1 1
BACE1 MAOA 0 0 245 246 1 1
BACE1 TGM2 0 0 66 227 1 2
BACE1 TP53 0 0 358 358 1 2
BACE1 PPP1CC 0 0 108 150 1 1
BACE1 HTT 0 0 469 502 1 2
BACE1 EGFR 0 0 345 482 1 2
BACE1 CLEC4G 0 0 0 185 1 1
BACE1 LAMP1 0 0 370 427 1 2
BACE1 SLC2A1 0 0 161 185 1 2
BACE1 NEDD8 0 0 52 177 1 2
BACE1 EDN3 0 0 113 168 1 1
BACE1 ADH1A 0 0 54 189 1 1
BACE1 CT83 0 0 194 209 1 1
BACE1 NCOR2 0 0 66 177 1 1
BACE1 QPCT 0 0 452 452 1 1
BACE1 GIG25 0 0 268 268 1 1
BACE1 RAB10 0 0 125 159 1 1
BACE1 DNAJA1 0 0 0 163 1 1
BACE1 MAP1A 0 0 95 156 1 2
BACE1 CTSA 0 0 54 402 1 1
BACE1 HDAC2 0 0 212 282 1 1
BACE1 FKBP4 0 0 81 244 1 1
BACE1 NEFL 0 0 322 321 1 1
BACE1 PDE4D 0 0 167 186 1 1
BACE1 SIRT6 0 0 261 299 1 2
BACE1 KCNC4 312 0 0 330 1 1
BACE1 EPHA4 0 0 140 191 1 1
BACE1 KCNIP3 0 0 202 252 1 1
BACE1 AGER 0 0 504 504 1 2
BACE1 CNTNAP1 0 0 150 178 1 1
BACE1 CD33 0 0 323 335 1 1
BACE1 NRG4 0 0 113 183 1 1
BACE1 VPS26A 0 0 562 562 1 1
BACE1 CDH1 0 0 181 193 1 2
BACE1 COX10 0 0 108 253 1 1
BACE1 VPS35 0 0 414 440 1 2
BACE1 MACF1 0 0 0 171 1 1
BACE1 ADAP1 0 0 59 212 1 1
BACE1 REXO2 0 0 641 641 1 1
BACE1 KLHL1 0 0 61 208 1 1
BACE1 PDE4A 0 0 161 206 1 1
BACE1 DRD2 0 0 261 261 1 1
BACE1 BCHE 0 0 686 695 1 1
BACE1 GATA1 0 0 120 233 1 1
BACE1 GABRB1 0 0 120 317 1 1
BACE1 ROCK2 0 0 108 168 1 1
BACE1 MAP1B 0 0 166 262 1 2
BACE1 PRDM15 0 0 52 172 1 1
BACE1 ALB 0 0 424 475 1 2
BACE1 CD68 0 0 166 270 1 2
BACE1 CCL2 0 0 233 232 1 2
BACE1 EIF4A1 0 0 127 187 1 1
BACE1 ENPEP 0 0 155 188 1 1
BACE1 BBS10 0 0 0 211 1 1
BACE1 ELAVL1 0 0 294 294 1 2
BACE1 CSNK1D 600 0 72 618 1 1
BACE1 TYROBP 0 0 166 165 1 1
BACE1 PMP2 0 0 0 197 1 1
BACE1 MME 0 0 681 728 1 1
BACE1 SORBS3 0 0 122 200 1 1
BACE1 SPTBN4 0 0 0 185 1 1
BACE1 MS4A6E 0 0 203 203 1 1
BACE1 PVALB 0 0 251 276 1 1
BACE1 PLD3 0 0 254 270 1 1
BACE1 SCARB1 0 0 134 161 1 1
BACE1 IL4 0 0 213 213 1 1
BACE1 EP300 0 0 160 174 1 2
BACE1 ADIPOR1 0 0 122 152 1 1
BACE1 CDK5 0 0 698 698 1 2
BACE1 ZCWPW1 0 0 193 193 1 1
BACE1 TARBP2 0 0 82 332 1 1
BACE1 ROCK1 0 0 160 193 1 2
BACE1 PLS3 0 0 0 160 1 1
BACE1 ELOVL1 0 0 67 241 1 1
BACE1 CYCS 0 0 324 338 1 2
BACE1 GGA1 973 600 985 999 1 1
BACE1 SLC1A2 0 0 266 288 1 1
BACE1 PPIAL4G 0 0 0 167 1 1
BACE1 PCSK1 0 0 0 328 1 1
BACE1 FCGRT 0 0 123 156 1 1
BACE1 ATP5A1 305 0 0 360 1 1
BACE1 SORCS2 0 0 266 360 1 1
BACE1 GNAZ 0 0 0 177 1 1
BACE1 PAWR 0 0 477 477 1 1
BACE1 EGF 0 0 370 383 1 2
BACE1 MAGEH1 0 0 392 437 1 1
BACE1 CRHR1 0 0 171 171 1 1
BACE1 DICER1 0 0 341 356 1 1
BACE1 CLTC 0 0 123 335 1 1
BACE1 CTSH 0 0 0 267 1 1
BACE1 GPHN 0 0 119 157 1 1
BACE1 HSPA4 0 0 315 375 1 1
BACE1 FBXO33 0 0 66 199 1 1
BACE1 PPARA 0 0 282 293 1 2
BACE1 CETP 0 0 142 184 1 1
BACE1 ACHE 0 0 686 695 1 2
BACE1 TRPC6 0 0 329 329 1 1
BACE1 XPO5 0 0 203 220 1 1
BACE1 HSP90B1 0 0 266 293 1 1
BACE1 NGB 0 0 306 317 1 1
BACE1 CHAT 0 0 457 457 1 1
BACE1 VAMP1 0 0 170 199 1 1
BACE1 GPX4 0 0 123 182 1 2
BACE1 BLVRA 0 0 150 368 1 1
BACE1 STAB2 0 0 0 193 1 1
BACE1 MBTPS2 0 0 180 179 1 1
BACE1 PRNP 0 0 649 825 1 2
BACE1 FXR1 0 0 76 155 1 1
BACE1 XPNPEP2 0 0 124 329 1 1
BACE1 PPIL6 0 0 91 177 1 1
BACE1 BMP1 0 0 120 169 1 1
BACE1 HBG1 0 0 0 166 1 1
BACE1 WRAP53 0 0 95 175 1 1
BACE1 MAPK8 0 0 207 238 1 2
BACE1 PLD1 0 0 218 235 1 2
BACE1 MAP2K4 0 0 74 576 1 1
BACE1 GABBR2 0 0 202 213 1 1
BACE1 SEPT4 0 0 67 221 1 1
BACE1 GAP43 0 0 325 359 1 1
BACE1 UCHL1 0 0 338 363 1 2
BACE1 IRS2 0 0 154 192 1 1
BACE1 APBB1 0 0 661 679 1 1
BACE1 TAGLN3 0 0 0 155 1 1
BACE1 SCAMP1 0 0 67 165 1 1
BACE1 MFN1 0 0 181 235 1 2
BACE1 EIF2AK2 0 0 97 220 1 2
BACE1 TREM2 0 0 470 470 1 1
BACE1 PCSK4 0 0 0 328 1 1
BACE1 JAG1 0 0 234 246 1 1
BACE1 ARL10 0 0 103 150 1 1
BACE1 CTSF 0 0 74 326 1 1
BACE1 FYN 0 0 370 397 1 1
BACE1 GRIN2A 0 0 323 323 1 1
BACE1 TPP2 0 0 0 259 1 1
BACE1 SPTBN1 0 0 47 181 1 1
BACE1 BSN 0 0 157 202 1 2
BACE1 TBL1X 0 0 135 153 1 1
BACE1 SOD1 0 0 415 442 1 2
BACE1 CORO2B 0 0 0 158 1 1
BACE1 TPP1 0 0 45 204 1 1
BACE1 CYP19A1 0 0 306 306 1 2
BACE1 WDR31 0 0 0 169 1 1
BACE1 SI 0 0 150 161 1 1
BACE1 DPYSL2 0 0 217 242 1 1
BACE1 GAS2L2 0 0 0 171 1 1
BACE1 CCDC47 0 0 0 216 1 1
BACE1 FABP3 0 0 62 188 1 1
BACE1 SCN3A 0 0 161 218 1 1
BACE1 JUN 0 0 394 407 1 2
BACE1 NRG3 0 0 499 516 1 1
BACE1 NOS1 0 0 208 228 1 1
BACE1 EIF2AK1 0 0 282 297 1 1
BACE1 SEZ6L 0 0 390 513 1 1
BACE1 GAS2L1 0 0 0 171 1 1
BACE1 PIK3CG 0 0 181 212 1 1
BACE1 ECE2 0 0 322 344 1 1
BACE1 GSTA4 0 0 0 172 1 1
BACE1 ERBB4 0 0 405 442 1 1
BACE1 AIF1 0 0 518 531 1 2
BACE1 CPD 0 0 61 292 1 1
BACE1 ATG13 0 0 117 224 1 2
BACE1 SELP 0 0 96 355 1 1
BACE1 HNRNPF 0 0 0 188 1 1
BACE1 FGF1 0 0 91 158 1 1
BACE1 TTF2 0 0 0 159 1 1
BACE1 SGTB 0 0 0 179 1 1
BACE1 SELL 0 0 442 456 1 1
BACE1 THY1 0 0 319 409 1 1
BACE1 ABCG1 0 0 180 192 1 2
BACE1 MMP9 0 0 288 340 1 2
BACE1 RANBP9 462 0 103 541 1 1
BACE1 FAR1 0 0 74 191 1 1
BACE1 MAPK3 0 0 338 371 1 2
BACE1 TKTL1 0 0 0 171 1 1
BACE1 LRRN1 0 0 344 370 1 1
BACE1 SQSTM1 0 0 170 169 1 2
BACE1 SIM2 0 0 45 185 1 1
BACE1 HSP90AA1 0 0 287 313 1 2
BACE1 HDAC4 0 0 123 192 1 2
BACE1 CHRM1 0 0 181 181 1 1
BACE1 SYT1 0 0 280 303 1 1
BACE1 SOX2 0 0 170 202 1 2
BACE1 CRP 0 0 184 183 1 2
BACE1 UGCG 0 0 134 171 1 1
BACE1 PSEN1 270 0 977 985 1 2
BACE1 DNAJA4 0 0 0 163 1 1
BACE1 TP73 0 0 46 393 1 2
BACE1 ADH1B 0 0 0 177 1 1
BACE1 PTPRC 0 0 139 159 1 1
BACE1 ICAM1 0 0 164 170 1 2
BACE1 PPIAL4C 0 0 0 167 1 1
BACE1 ATG9A 0 0 107 186 1 2
BACE1 HNRNPH1 0 0 112 173 1 1
BACE1 CSF2RA 0 0 158 157 1 1
BACE1 SFTPB 0 0 0 299 1 1
BACE1 GSN 0 0 150 168 1 1
BACE1 SNX8 0 0 150 208 1 1
BACE1 STX6 0 0 143 180 1 1
BACE1 FABP5 0 0 50 194 1 1
BACE1 SYN1 0 0 409 438 1 1
BACE1 MICAL2 0 0 55 177 1 1
BACE1 STX1A 0 0 180 269 1 1
BACE1 GNA12 0 0 0 177 1 1
BACE1 F10 0 0 143 196 1 1
BACE1 CUTA 0 0 704 711 1 1
BACE1 TMED9 0 0 69 186 1 1
BACE1 TFCP2 0 0 182 199 1 1
BACE1 F2 0 0 97 159 1 1
BACE1 LRP8 0 0 454 501 1 1
BACE1 CDC42 0 0 156 190 1 2
BACE1 CCT3 0 0 0 172 1 1
BACE1 SLC2A4 0 0 170 194 1 1
BACE1 ATXN2 0 0 151 221 1 1
BACE1 FOXO3 0 0 186 186 1 2
BACE1 APOE 0 0 801 801 1 2
BACE1 SLC24A4 0 0 146 169 1 1
BACE1 COMT 0 0 162 172 1 1
BACE1 RTN3 270 800 799 974 1 1
BACE1 HARS2 0 0 384 389 1 1
BACE1 RNF112 0 0 0 175 1 1
BACE1 DAO 0 0 81 186 1 2
BACE1 SIM1 0 0 0 181 1 1
BACE1 XPNPEP3 0 0 231 286 1 1
BACE1 RAB11A 0 0 325 372 1 2
BACE1 YY1 0 0 260 279 1 1
BACE1 STXBP2 0 0 0 200 1 1
BACE1 SORCS1 0 0 417 473 1 1
BACE1 HLA-DOB 0 0 0 203 1 1
BACE1 MDH2 0 0 45 183 1 1
BACE1 ARHGAP32 0 0 181 201 1 1
BACE1 DCX 0 0 253 252 1 1
BACE1 TBK1 0 0 63 154 1 2
BACE1 GSTA3 0 0 46 161 1 1
BACE1 PRKCD 0 0 160 178 1 2
BACE1 LOC388210 0 0 0 195 1 1
BACE1 GLUL 0 0 145 170 1 1
BACE1 VDAC1 0 0 291 323 1 2
BACE1 TMEM37 0 0 282 282 1 1
BACE1 TGFB1 0 0 113 178 1 2
BACE1 RAB7B 0 0 341 401 1 1
BACE1 SUMO1 0 0 629 629 1 1
BACE1 PPIAL4B 0 0 0 167 1 1
BACE1 VCAM1 0 0 142 160 1 1
BACE1 SPPL2B 0 0 184 196 1 1
BACE1 ENSG00000269547 0 0 0 194 1 1
BACE1 MBTPS1 0 0 103 301 1 1
BACE1 INPP5D 0 0 141 200 1 1
BACE1 RASD2 0 0 82 162 1 1
BACE1 PPP1R9B 0 0 188 188 1 1
BACE1 GRIK1 0 0 119 162 1 1
BACE1 CST3 0 0 292 456 1 1
BACE1 DROSHA 0 0 261 269 1 1
BACE1 PLXDC2 0 0 205 245 1 1
BACE1 TMED10 0 0 458 457 1 1
BACE1 NTRK2 0 0 323 374 1 1
BACE1 LRP4 0 0 230 255 1 1
BACE1 SCN5A 0 0 134 227 1 1
BACE1 AXL 0 0 66 170 1 2
BACE1 SNUPN 0 0 108 216 1 1
BACE1 DLD 0 0 108 217 1 2
BACE1 RTN4 270 800 960 994 1 1
BACE1 CST6 0 0 0 182 1 1
BACE1 PDE5A 0 0 166 184 1 1
BACE1 EHD1 0 0 156 236 1 1
BACE1 ADH4 0 0 0 177 1 1
BACE1 NFATC4 0 0 170 169 1 1
BACE1 PINK1 0 0 321 364 1 2
BACE1 UBQLN1 0 0 189 265 1 1
BACE1 GRM5 0 0 265 285 1 1
BACE1 MAG 0 0 202 239 1 1
BACE1 CTSO 0 0 0 246 1 1
BACE1 ECE1 0 0 326 348 1 1
BACE1 NGF 0 0 467 478 1 2
BACE1 NEDD8-MDP1 0 0 0 167 1 1
BACE1 MEP1B 0 0 108 301 1 1
BACE1 TH 0 0 283 302 1 2
BACE1 GSTA2 0 0 0 157 1 1
BACE1 PRKRA 0 0 60 223 1 1
BACE1 TPM3 0 0 161 181 1 1
BACE1 ITM2B 270 0 478 609 1 1
BACE1 MGAM 0 0 150 161 1 1
BACE1 PDE4B 0 0 95 169 1 1
BACE1 CLHC1 0 0 0 273 1 1
BACE1 SYNGAP1 0 0 90 186 1 1
BACE1 PITX3 0 0 234 253 1 1
BACE1 ENSG00000196136 0 0 268 285 1 1
BACE1 FGF2 0 0 210 224 1 2
BACE1 MGAT3 0 0 324 338 1 1
BACE1 GMFB 0 0 0 229 1 1
BACE1 CD63 0 0 234 252 1 2
BACE1 CD2AP 0 0 390 390 1 1
BACE1 IREB2 0 0 96 185 1 1
BACE1 EDEM1 0 0 307 312 1 2
BACE1 APOB 0 0 194 324 1 2
BACE1 MAPK1 0 0 194 228 1 2
BACE1 IGF1 0 0 322 339 1 2
BACE1 SYNE1 0 0 0 171 1 1
BACE1 GSTM5 0 0 0 157 1 1
BACE1 CCT2 0 0 0 166 1 1
BACE1 EXOC3L2 0 0 61 163 1 1
BACE1 APBA1 0 0 375 416 1 1
BACE1 GSAP 0 0 460 516 1 1
BACE1 CD44 0 0 157 156 1 2
BACE1 BDNF 0 0 602 627 1 2
BACE1 SMAP2 0 0 0 197 1 1
BACE1 ABHD6 0 0 99 153 1 1
BACE1 GNAI2 0 0 0 197 1 1
BACE1 CELF1 0 0 170 188 1 1
BACE1 SNAP25 0 0 334 366 1 1
BACE1 HR 0 0 167 186 1 1
BACE1 SNX33 0 0 242 247 1 1
BACE1 PMP22 0 0 112 164 1 1
BACE1 CBSL 0 0 203 298 1 1
BACE1 C8orf4 0 0 293 293 1 1
BACE1 SMPD2 0 0 306 306 1 1
BACE1 APH1B 0 0 602 609 1 1
BACE1 IFI30 0 0 0 242 1 1
BACE1 HRSP12 0 0 0 245 1 1
BACE1 GPC1 0 0 150 186 1 1
BACE1 COA8 0 0 137 237 1 1
BACE1 ANKK1 0 0 0 152 1 1
BACE1 AHCY 0 0 45 175 1 1
BACE1 SMN2 0 0 170 169 1 1
BACE1 RHEB 0 0 265 295 1 2
BACE1 SH3BGR 0 0 0 252 1 1
BACE1 ANXA7 0 0 167 167 1 1
BACE1 CNTN4 0 0 60 154 1 1
BACE1 LDLR 0 0 417 432 1 2
BACE1 TUBA1A 305 0 57 335 1 1
BACE1 GNB2L1 0 0 67 191 1 1
BACE1 GBA 0 0 180 209 1 1
BACE1 PTK2B 0 0 183 183 1 1
BACE1 IDE 0 0 766 817 1 1
BACE1 UBB 0 0 61 157 1 1
BACE1 ANK2 0 0 74 152 1 1
BACE1 TXN 0 0 157 217 1 1
BACE1 CNST 0 0 204 326 1 1
BACE1 LCP1 0 0 0 160 1 1
BACE1 OPRM1 0 0 279 279 1 1
BACE1 LRP6 0 0 181 303 1 1
BACE1 ENSG00000264813 0 0 373 398 1 1
BACE1 HMGCR 0 0 259 320 1 1
BACE1 TMEM27 0 0 391 484 1 1
BACE1 GSTA1 0 0 85 195 1 1
BACE1 YWHAQ 0 0 518 544 1 1
BACE1 OLIG2 0 0 140 181 1 1
BACE1 DRP2 0 0 0 169 1 1
BACE1 EIF4E 0 0 170 188 1 2
BACE1 CCND1 0 0 170 169 1 2
BACE1 SEMA3A 0 0 210 210 1 1
BACE1 NOS3 0 0 294 312 1 2
BACE1 SPTLC2 0 0 212 253 1 1
BACE1 FAM3B 0 0 0 288 1 1
BACE1 ACTN1 0 0 66 165 1 1
BACE1 MTHFR 0 0 171 171 1 1
BACE1 CNTN6 0 0 141 179 1 1
BACE1 AP1G2 0 0 307 351 1 1
BACE1 UBE2I 0 0 98 162 1 1
BACE1 NT5C1A 0 0 178 177 1 1
BACE1 GNAI1 0 0 0 216 1 1
BACE1 CA4 0 0 184 238 1 1
BACE1 NRXN1 0 0 320 324 1 1
BACE1 RAD23B 0 0 0 178 1 1
BACE1 NRGN 0 0 406 406 1 1
BACE1 DYX1C1 0 0 0 208 1 1
BACE1 KCNA3 0 0 112 195 1 1
BACE1 SHC1 0 0 215 229 1 1
BACE1 FERMT2 0 0 181 201 1 1
BACE1 NECAB1 0 0 0 207 1 1
BACE1 RPL37 0 0 0 154 1 1
BACE1 TYRO3 0 0 72 158 1 1
BACE1 CTSD 0 0 639 284 1 2
BACE1 SERF1B 0 0 459 459 1 1
BACE1 SNX17 0 0 262 262 1 1
BACE1 GFAP 0 0 504 547 1 2
BACE1 GSTA5 0 0 0 157 1 1
BACE1 CLMN 0 0 0 171 1 1
BACE1 LDLRAD3 0 0 134 159 1 1
BACE1 ACTG1 0 0 188 219 1 1
BACE1 MICALL2 0 0 0 160 1 1
BACE1 TJP1 0 0 161 181 1 1
BACE1 SELE 0 0 95 355 1 1
BACE1 ATG7 0 0 184 238 1 2
BACE1 AGPS 0 0 138 156 1 1
BACE1 PANK2 0 0 70 168 1 1
BACE1 DNM1L 0 0 246 320 1 2
BACE1 PTEN 0 0 261 280 1 2
BACE1 MBP 0 0 280 300 1 2
BACE1 NFIA 0 0 54 427 1 1
BACE1 VEGFA 0 0 265 265 1 2
BACE1 GLIPR1 0 0 155 207 1 1
BACE1 MAPK10 0 0 235 279 1 2
BACE1 CFL1 0 0 290 425 1 1
BACE1 DNAJC1 0 0 0 155 1 1
BACE1 MAPK14 0 0 212 248 1 2
BACE1 LEP 0 0 276 276 1 1
BACE1 PHF6 0 0 44 164 1 1
BACE1 NFKBIA 0 0 194 202 1 2
BACE1 MAP3K3 0 0 90 156 1 1
BACE1 COPS5 270 0 74 310 1 1
BACE1 CTSK 0 0 112 341 1 2
BACE1 ZFP36L1 0 0 0 166 1 1
BACE1 TSPAN33 0 0 101 199 1 1
BACE1 MPP2 0 0 49 171 1 1
BACE1 PSMC5 0 0 0 175 1 1
BACE1 GNA11 0 0 0 166 1 1
BACE1 ITGAM 0 0 162 180 1 1
BACE1 SEZ6L2 0 0 362 476 1 1
BACE1 SIRT1 0 0 460 509 1 2
BACE1 MAPK8IP3 0 0 123 155 1 1
BACE1 CTSB 0 0 566 668 1 2
BACE1 PTPRZ1 0 0 161 198 1 1
BACE1 FUS 0 0 295 295 1 2
BACE1 PTPN1 0 0 241 269 1 1
BACE1 ENSG00000256349 0 0 0 177 1 1
BACE1 XBP1 0 0 210 210 1 2
BACE1 SNX6 305 0 699 784 1 1
BACE1 GRIN1 0 0 193 316 1 1
BACE1 TIA1 0 0 76 158 1 1
BACE1 ATG5 0 0 218 257 1 2
BACE1 ADAM17 0 0 664 776 1 1
BACE1 SUGT1 0 0 0 152 1 1
BACE1 LRP10 0 0 275 387 1 1
BACE1 HTN3 0 0 233 233 1 1
BACE1 HOMER3 0 0 123 161 1 1
BACE1 LY6E 0 0 206 206 1 1
BACE1 GCC1 0 0 55 200 1 1
BACE1 EHBP1 0 0 0 160 1 1
BACE1 DYRK1A 0 0 323 337 1 1
BACE1 NAV3 0 0 211 226 1 1
BACE1 MGLL 0 0 210 267 1 1
BACE1 ADAM19 0 0 288 339 1 1
BACE1 HTR4 0 0 174 173 1 1
BACE1 CST4 0 0 60 198 1 1
BACE1 PMPCB 0 0 0 174 1 1
BACE1 RCOR1 0 0 241 240 1 1
BACE1 AKT3 0 0 62 153 1 2
BACE1 CASR 0 0 157 156 1 2
BACE1 TMEM30B 0 0 0 163 1 1
BACE1 GPX1 0 0 108 160 1 1
BACE1 CACHD1 0 0 134 270 1 1
BACE1 ATP8A1 0 0 0 346 1 1
BACE1 NCAM1 0 0 166 194 1 1
BACE1 EIF4A2 0 0 146 194 1 1
BACE1 FKBP10 0 0 0 155 1 1
BACE1 CAMK4 0 0 85 153 1 1
BACE1 PICALM 0 0 504 505 1 1
BACE1 ARHGEF5 0 0 307 322 1 1
BACE1 SNX2 0 0 204 204 1 1
BACE1 DNM1 0 0 241 347 1 1
BACE1 HSPA5 305 0 282 560 1 2
BACE1 FGF20 0 0 243 270 1 1
BACE1 SOD2 0 0 206 235 1 2
BACE1 APLP1 0 0 681 740 1 1
BACE1 FOS 0 0 234 245 1 2
BACE1 MAT1A 0 0 0 208 1 1
BACE1 YWHAZ 0 0 119 167 1 1
BACE1 SNCB 0 0 146 202 1 1
BACE1 HM13 0 0 559 568 1 1
BACE1 RIPPLY3 0 0 0 188 1 1
BACE1 PITRM1 0 0 60 224 1 1
BACE1 CNP 0 0 112 153 1 1
BACE1 HRH3 0 0 211 211 1 1
BACE1 SLC40A1 0 0 150 220 1 1
BACE1 GSTM2 0 0 0 162 1 1
BACE1 PDIA3 494 0 112 562 1 1
BACE1 GNAI3 0 0 0 196 1 2
BACE1 CDK5R1 0 0 434 446 1 1
BACE1 FKBP9 0 0 56 176 1 1
BACE1 ARF6 0 0 421 445 1 1
BACE1 SNAPIN 0 0 273 273 1 1
BACE1 STXBP1 0 0 81 279 1 1
BACE1 NDUFA6 0 0 0 163 1 1
BACE1 NR6A1 0 0 0 157 1 1
BACE1 MAOB 0 0 451 464 1 1
BACE1 LRRK2 0 0 391 455 1 2
BACE1 GRIN2B 0 0 408 408 1 1
BACE1 GNAO1 0 0 72 225 1 1
BACE1 CST5 0 0 0 241 1 1
BACE1 LRP2 0 0 219 231 1 1
BACE1 TLR2 0 0 142 162 1 2
BACE1 ANKRD45 0 0 0 189 1 1
BACE1 ATG12 0 0 137 227 1 2
BACE1 CYP46A1 0 0 370 383 1 1
BACE1 ALOX5 0 0 267 267 1 1
BACE1 PTPN5 0 0 137 186 1 1
BACE1 CSTB 0 0 134 242 1 1
BACE1 TRPC4 0 0 154 153 1 1
BACE1 PPIA 305 0 129 451 1 1
BACE1 HSPA1B 0 0 0 155 1 1
BACE1 MMP14 0 0 167 192 1 1
BACE1 VPS29 0 0 308 316 1 1
BACE1 AP1G1 0 0 277 365 1 1
BACE1 RPSA 0 0 117 154 1 1
BACE1 NFIB 0 0 0 420 1 1
BACE1 TNFRSF21 0 0 560 560 1 1
BACE1 LIMK1 0 0 162 195 1 1
BACE1 IDS 0 0 107 219 1 1
BACE1 TSPO 0 0 211 211 1 1
BACE1 DNAJA2 0 0 44 166 1 1
BACE1 SSPN 0 0 0 163 1 1
BACE1 HDAC1 0 0 216 285 1 2
BACE1 CRYAB 0 0 66 161 1 2
BACE1 PHB2 0 0 156 194 1 1
BACE1 CSTF2 0 0 0 184 1 1
BACE1 FOLH1 0 0 143 176 1 1
BACE1 HIP1R 0 0 0 190 1 1
BACE1 SST 0 0 134 179 1 1
BACE1 CALM2 0 0 0 152 1 1
BACE1 FABP4 0 0 46 300 1 1
BACE1 RBL2 0 0 451 451 1 1
BACE1 PTGS1 0 0 157 199 1 1
BACE1 NOTCH1 0 0 518 529 1 2
BACE1 PSEN2 0 0 753 853 1 1
BACE1 ABCB11 0 0 0 188 1 1
BACE1 SORT1 270 0 482 656 1 1
BACE1 MT-CO3 0 0 0 161 1 1
BACE1 CALM1 0 0 60 234 1 1
BACE1 POTEF 0 0 125 198 1 1
BACE1 KPNA1 0 0 0 154 1 1
BACE1 TTC33 0 0 0 179 1 1
BACE1 IL6 0 0 456 468 1 2
BACE1 CHMP2B 0 0 163 182 1 2
BACE1 UBE2A 0 0 113 155 1 1
BACE1 TNFRSF1A 0 0 234 234 1 1
BACE1 CCT5 0 0 0 168 1 1
BACE1 CMPK1 213 0 0 219 1 1
BACE1 IL1B 0 0 504 504 1 2
BACE1 DLG2 0 0 184 255 1 1
BACE1 SP1 0 0 321 338 1 2
BACE1 PSMC2 0 0 0 193 1 1
BACE1 HIF1A 0 0 322 321 1 2
BACE1 EDN1 0 0 230 229 1 1
BACE1 SIRT5 0 0 273 339 1 1
BACE1 GRIK3 0 0 123 184 1 1
BACE1 KCNQ1 270 0 130 355 1 1
BACE1 CLN3 0 0 96 179 1 2
BACE1 ADAP2 0 0 0 197 1 1
BACE1 STAB1 0 0 82 350 1 1
BACE1 SCN1A 0 0 415 440 1 1
BACE1 CDK2 0 0 189 275 1 2
BACE1 MAP1LC3A 0 0 81 184 1 2
BACE1 CLSTN3 0 0 113 153 1 1
BACE1 PACS2 0 0 0 153 1 1
BACE1 TNFRSF1B 0 0 113 184 1 1
BACE1 HBG2 0 0 0 166 1 1
BACE1 RHO 0 0 231 230 1 2
BACE1 PLA2G4A 0 0 181 200 1 1
BACE1 LONRF2 0 0 0 162 1 1
BACE1 ADCYAP1 0 0 126 164 1 1
BACE1 RAN 0 0 74 157 1 2
BACE1 ENSG00000250349 0 0 213 213 1 1
BACE1 SLC9A1 0 0 0 248 1 1
BACE1 BCL2L1 0 0 218 218 1 2
BACE1 DNMT3B 0 0 307 307 1 1
BACE1 MAPK8IP1 0 0 272 319 1 1
BACE1 DNMT3A 0 0 622 622 1 2
BACE1 CHD7 0 0 643 656 1 1
BACE1 ATG14 0 0 90 179 1 2
BACE1 TSPAN12 0 0 181 232 1 1
BACE1 PTPN9 0 0 127 175 1 1
BACE1 GP9 0 0 0 157 1 1
BACE1 TLR4 0 0 259 276 1 2
BACE1 KIF1A 0 0 91 202 1 1
BACE1 NOS2 0 0 207 227 1 2
BACE1 ATP8A2 0 0 0 217 1 1
BACE1 JAG2 0 0 203 215 1 1
BACE1 APOA1 0 0 233 249 1 1
BACE1 SLC18A3 0 0 137 190 1 1
BACE1 GTPBP2 0 0 53 170 1 1
BACE1 ARF1 0 0 96 156 1 1
BACE1 RGS8 0 0 81 194 1 1
BACE1 CADM3 0 0 108 192 1 1
BACE1 CCL5 0 0 214 214 1 2
BACE1 SERP1 0 0 54 244 1 1
BACE1 PCSK7 0 0 296 507 1 1
BACE1 IFNG 0 0 193 226 1 2
BACE1 NSF 0 0 48 167 1 2
BACE1 HSPD1 0 0 73 306 1 1
BACE1 SH3GLB2 0 0 72 175 1 1
BACE1 TAGLN 0 0 0 151 1 1
BACE1 PCSK6 0 0 76 353 1 1
BACE1 GRIA2 0 0 279 305 1 1
BACE1 GRIA4 0 0 122 158 1 1
BACE1 FLNC 0 0 0 164 1 1
BACE1 PLEC 0 0 0 172 1 1
BACE1 EPO 0 0 134 157 1 2
BACE1 PLK1 0 0 90 163 1 2
BACE1 NAV1 0 0 538 551 1 1
BACE1 RELN 0 0 288 306 1 1
BACE1 RANBP2 0 0 0 167 1 1
BACE1 RGS4 0 0 108 175 1 1
BACE1 SLC6A1 0 0 73 157 1 1
BACE1 SHANK1 0 0 97 160 1 1
BACE1 SYNPO 0 0 185 210 1 1
BACE1 EFNA5 0 0 173 179 1 1
BACE1 PARK7 0 0 325 361 1 2
BACE1 CHI3L1 0 0 189 206 1 1
BACE1 SRI 0 0 107 172 1 1
BACE1 AHCYL1 0 0 0 171 1 1
BACE1 HSD17B10 0 0 125 186 1 1
BACE1 CTSV 0 0 0 267 1 1
BACE1 ACER3 0 0 0 163 1 1
BACE1 MECP2 0 0 270 270 1 1
BACE1 NFE2L2 0 0 243 242 1 2
BACE1 EHMT2 0 0 142 197 1 2
BACE1 MAP2K1 0 0 127 175 1 1
BACE1 SLC30A3 0 0 145 227 1 1
BACE1 PPIF 0 0 193 299 1 1
BACE1 LRRTM3 0 0 537 558 1 1
BACE1 RTN2 0 0 520 583 1 1
BACE1 FURIN 213 900 468 968 1 1
BACE1 DSP 0 0 0 171 1 1
BACE1 NPY 0 0 204 204 1 1
BACE1 CYB5A 0 0 0 191 1 1
BACE1 FKBP7 0 0 97 188 1 1
BACE1 SMAP1 0 0 0 197 1 1
BACE1 SLC6A4 0 0 222 230 1 1
BACE1 IL18 0 0 176 175 1 2
BACE1 NCSTN 270 0 968 979 1 1
BACE1 MYC 0 0 320 319 1 2
BACE1 IL1R1 0 0 456 456 1 1
BACE1 PPIG 0 0 107 192 1 1
BACE1 FABP7 0 0 95 195 1 1
BACE1 ATP1B1 213 0 0 255 1 1
BACE1 H1F0 0 0 134 153 1 1
BACE1 ENSG00000279576 0 0 233 232 1 1
BACE1 RAB3B 0 0 122 215 1 1
BACE1 IGF1R 0 0 210 245 1 2
BACE1 SDHC 0 0 182 199 1 1
BACE1 HLA-DRB5 0 0 155 154 1 1
BACE1 KALRN 0 0 108 168 1 1
BACE1 NPC1 0 0 257 279 1 2
BACE1 ZBTB22 0 0 360 377 1 1
BACE1 DZIP3 0 0 108 165 1 1
BACE1 APOH 0 0 0 155 1 1
BACE1 GNAT3 0 0 0 177 1 1
BACE1 MAP2 0 0 341 380 1 2
BACE1 SPTBN2 0 0 0 160 1 1
BACE1 MX1 0 0 0 179 1 1
BACE1 FKBP1B 0 0 66 162 1 1
BACE1 APPL1 0 0 211 275 1 1
BACE1 GNAT2 0 0 0 177 1 1
BACE1 SYT11 0 0 146 228 1 1
BACE1 FCER2 0 0 0 156 1 1
BACE1 FNTA 0 0 108 271 1 1
BACE1 ADH1C 0 0 0 177 1 1
BACE1 ZFAND4 0 0 0 160 1 1
BACE1 HGS 0 0 373 396 1 2
BACE1 SRSF1 0 0 74 180 1 1
BACE1 CAMKK2 0 0 127 157 1 2
BACE1 PYCR1 0 0 432 444 1 1
BACE1 ELAVL2 0 0 286 301 1 1
BACE1 EDN2 0 0 203 203 1 1
BACE1 ERN1 0 0 181 253 1 2
BACE1 STAT3 0 0 296 300 1 2
BACE1 EZH2 0 0 151 173 1 2
BACE1 ADAM9 0 0 564 591 1 1
BACE1 SNX12 0 0 778 778 1 1
BACE1 AGO2 0 0 243 278 1 2
BACE1 MKKS 0 0 0 173 1 1
BACE1 CFTR 0 0 103 194 1 2
BACE1 ADORA3 0 0 155 154 1 1
BACE1 CCS 0 0 722 749 1 2
BACE1 CSTF2T 0 0 0 184 1 1
BACE1 FBXO6 0 0 134 212 1 1
BACE1 STAU1 0 0 259 492 1 1
BACE1 RAB4A 0 0 231 262 1 1
BACE1 CST2 0 0 0 182 1 1
BACE1 NRXN3 0 0 180 185 1 1
BACE1 SNAP23 0 0 158 157 1 1
BACE1 EXO1 0 0 269 285 1 1
BACE1 VKORC1L1 0 0 0 168 1 1
BACE1 MCAT 0 0 134 166 1 1
BACE1 PLP1 0 0 175 199 1 1
BACE1 SELPLG 213 0 310 433 1 1
BACE1 DDIT3 0 0 245 244 1 2
BACE1 EXOC3L4 0 0 0 168 1 1
BACE1 HDAC8 0 0 73 155 1 1
BACE1 CP 0 0 119 201 1 1
BACE1 FBXL20 0 0 113 197 1 1
BACE1 RAB9B 0 0 0 150 1 1
BACE1 HIST1H4E 0 0 123 155 1 1
BACE1 HYOU1 312 0 66 394 1 1
BACE1 CERS2 0 0 122 211 1 1
BACE1 RYR1 0 0 243 243 1 2
BACE1 CADPS 0 0 0 218 1 1
BACE1 RMDN1 0 0 0 160 1 1
BACE1 SNX15 0 0 243 260 1 1
BACE1 MXRA8 0 0 622 629 1 1
BACE1 PLG 0 0 210 243 1 1
BACE1 LGALS4 0 0 324 323 1 1
BACE1 SLC3A2 0 0 345 360 1 1
BACE1 DPP4 0 0 181 199 1 1
BACE1 BSG 0 0 213 262 1 1
BACE1 FKBP5 0 0 103 262 1 1
BACE1 ABCA1 0 0 401 414 1 2
BACE1 IAPP 270 0 341 502 1 2
BACE1 RPS12 0 0 0 160 1 1
BACE1 DCTN1 0 0 124 172 1 1
BACE1 DNM2 0 0 155 245 1 1
BACE1 IL1A 0 0 209 209 1 1
BACE1 PPIAL4F 0 0 0 167 1 1
BACE1 CAMK2N1 0 0 66 194 1 1
BACE1 REEP5 0 0 75 164 1 1
BACE1 CASP8 0 0 164 178 1 2
BACE1 KNG1 0 0 125 167 1 1
BACE1 SORCS3 0 0 253 324 1 1
BACE1 CD276 0 0 308 307 1 1
BACE1 PIWIL4 0 0 253 252 1 1
BACE1 STMN2 0 0 141 166 1 1
BACE1 ZCCHC3 0 0 0 207 1 1
BACE1 EVPLL 0 0 0 171 1 1
BACE1 SGTA 0 0 0 179 1 1
BACE1 PGK1 0 0 82 184 1 2
BACE1 FLOT1 168 0 513 587 1 1
BACE1 ITGB1 0 0 107 157 1 1
BACE1 NRCAM 0 0 230 461 1 1
BACE1 VAMP2 0 0 260 301 1 1
BACE1 AMBP 0 0 0 156 1 1
BACE1 ENSG00000279782 0 0 0 167 1 1
BACE1 DBN1 0 0 231 238 1 1
BACE1 NRP1 0 0 300 300 1 1
BACE1 PLK2 0 0 134 225 1 1
BACE1 MAPK9 0 0 145 175 1 2
BACE1 HK1 0 0 95 156 1 1
BACE1 GULP1 0 0 263 263 1 1
BACE1 ITPR1 0 0 181 202 1 2
BACE1 CASP9 0 0 241 255 1 2
BACE1 POMC 0 0 141 250 1 1
BACE1 AKR1B1 0 0 218 230 1 1
BACE1 PRKAB2 0 0 0 220 1 1
BACE1 NRXN2 0 0 178 206 1 1
BACE1 TMX1 659 0 0 677 1 1
BACE1 PPIB 305 0 66 375 1 1
BACE1 CX3CR1 0 0 160 159 1 1
BACE1 TYR 0 0 165 185 1 2
BACE1 PMEL 0 0 217 265 1 1
BACE1 GNAS 0 0 63 168 1 1
BACE1 NES 0 0 181 198 1 2
BACE1 RPTOR 0 0 128 153 1 2
BACE1 HIST2H3PS2 0 0 194 217 1 1
BACE1 OTUB1 0 0 0 157 1 1
BACE1 NR3C1 0 0 261 272 1 1
BACE1 MX2 0 0 0 179 1 1
BACE1 FKBP1A 0 0 90 183 1 2
BACE1 CPT1B 0 0 0 155 1 1
BACE1 STX1B 0 0 108 355 1 1
BACE1 ARG1 0 0 94 169 1 2
BACE1 PRKAB1 0 0 0 220 1 2
BACE1 SERF1A 0 0 459 459 1 1
BACE1 ADIPOQ 0 0 143 162 1 2
BACE1 CMBL 0 0 0 239 1 2
BACE1 PDRG1 0 0 0 190 1 1
BACE1 ENO2 0 0 251 347 1 1
BACE1 CD8A 0 0 226 236 1 1
BACE1 CALR 305 0 325 560 1 1
BACE1 CFL2 0 0 0 224 1 1
BACE1 CYB5B 0 0 57 205 1 1
BACE1 PPL 0 0 0 181 1 1
BACE1 SNX3 0 0 209 209 1 1
BACE1 CSTF3 0 0 0 192 1 1
BACE1 CASS4 0 0 219 219 1 1
BACE1 MMP2 600 0 194 674 1 2
BACE1 MAT2A 0 0 0 208 1 1
BACE1 ZBTB5 0 0 81 160 1 1
BACE1 VSNL1 0 0 325 358 1 1
BACE1 TFAM 0 0 134 182 1 2
BACE1 VCP 0 0 155 171 1 2
BACE1 LAMP2 0 0 234 360 1 2
BACE1 HIP1 0 0 0 190 1 1
BACE1 SNX27 0 0 305 317 1 1
BACE1 ANK1 0 0 137 180 1 1
BACE1 GOLGA2 0 0 206 206 1 1
BACE1 RTN1 0 0 487 601 1 1
BACE1 GRN 0 0 344 379 1 1
BACE1 MEX3B 0 0 101 166 1 1
BACE1 CSTA 0 0 0 161 1 1
BACE1 CCR5 0 0 462 462 1 1
BACE1 HDLBP 0 0 154 168 1 1
BACE1 ALLC 0 0 103 242 1 1
BACE1 FKBP3 0 0 93 254 1 1
BACE1 CALB1 0 0 171 194 1 1
BACE1 KL 0 0 260 276 1 2
BACE1 PSAPL1 0 0 0 299 1 1
BACE1 KRT80 0 0 54 217 1 1
BACE1 PHF13 0 0 324 392 1 1
BACE1 SERPINA1 0 0 433 433 1 2
BACE1 BCL2L11 0 0 138 173 1 2
BACE1 SNX1 0 0 263 263 1 1
BACE1 KPNB1 270 0 0 277 1 1
BACE1 NBPF12 0 0 261 261 1 1
BACE1 ITPR3 0 0 144 166 1 1
BACE1 HEPH 0 0 75 162 1 1
BACE1 CASP1 0 0 210 224 1 2
BACE1 RTN4R 0 0 224 289 1 1
BACE1 NPC2 0 0 219 238 1 1
BACE1 PLAT 0 0 170 169 1 1
BACE1 SNCA 0 0 649 650 1 2
BACE1 SLC33A1 0 0 0 157 1 1
BACE1 PLS1 0 0 0 160 1 1
BACE1 APPBP2 0 0 134 222 1 1
BACE1 ZFP36 0 0 0 166 1 1
BACE1 CAV1 0 0 226 225 1 2
BACE1 HSPA1A 0 0 102 209 1 1
BACE1 NEFH 0 0 166 165 1 1
BACE1 ENSG00000258555 0 0 231 230 1 1
BACE1 CLDN5 0 0 150 169 1 1
BACE1 INS 0 0 502 512 1 2
BACE1 ACTB 0 0 563 599 1 2
BACE1 DNMT1 0 0 252 271 1 2
BACE1 STUB1 270 0 234 447 1 2
BACE1 SIRT3 0 0 297 333 1 2
BACE1 ENO3 0 0 0 164 1 1
BACE1 KEAP1 0 0 122 187 1 2
BACE1 KHSRP 213 0 0 213 1 1
BACE1 TRANK1 0 0 61 263 1 1
BACE1 PTGDR 0 0 496 496 1 1
BACE1 CALHM1 0 0 341 434 1 1
BACE1 TFEB 0 0 230 282 1 2
BACE1 GGA2 678 600 559 938 1 1
BACE1 HS3ST5 0 0 64 173 1 1
BACE1 BACE2 0 800 866 816 1 1
BACE1 HPGDS 0 0 194 286 1 1
BACE1 SGPL1 0 0 150 261 1 1
BACE1 SLC9A6 0 0 68 170 1 1
BACE1 HBE1 0 0 0 272 1 1
BACE1 ESR2 0 0 184 196 1 1
BACE1 ADH7 0 0 0 177 1 1
BACE1 CCT4 0 0 0 165 1 1
BACE1 SIRT7 0 0 252 291 1 2
BACE1 ABCG4 0 0 113 152 1 1
BACE1 ADORA2A 0 0 244 243 1 1
BACE1 SCN1B 0 0 166 165 1 1
BACE1 EPCAM 0 0 120 217 1 2
BACE1 EIF4G1 0 0 107 188 1 2
BACE1 KCNH2 0 0 244 243 1 1
BACE1 PARP1 0 0 150 297 1 2
BACE1 RHOA 0 0 170 204 1 2
BACE1 INSR 0 0 122 156 1 1
BACE1 HSPA8 0 0 193 261 1 2
BACE1 GSR 0 0 211 301 1 1
BACE1 PIWIL1 0 0 261 261 1 1
BACE1 KDM1A 0 0 138 179 1 2
BACE1 TARDBP 0 0 325 334 1 2
BACE1 ZDHHC20 0 0 144 175 1 1
BACE1 TOMM40 0 0 369 383 1 1
BACE1 MTTP 0 0 0 167 1 1
BACE1 TTC12 0 0 0 152 1 1
BACE1 SORL1 0 0 922 930 1 1
BACE1 SRC 0 0 247 276 1 2
BACE1 PRSS50 0 0 405 495 1 1
BACE1 HSPA12A 0 0 57 169 1 1
BACE1 SARS2 0 0 0 194 1 2
BACE1 SMARCC1 0 0 0 156 1 1
BACE1 USP8 270 0 75 346 1 1
BACE1 EEA1 0 0 407 449 1 2
BACE1 CD47 0 0 175 175 1 2
BACE1 CRIP2 0 0 0 160 1 1
BACE1 PCSK9 270 0 280 640 1 1
BACE1 A2M 0 0 360 360 1 1
BACE1 APOD 0 0 112 213 1 1
BACE1 EIF2AK3 0 0 258 274 1 2
BACE1 TTC1 0 0 60 173 1 1
BACE1 TUBB8B 305 0 0 331 1 1
BACE1 TSPAN17 0 0 129 218 1 1
BACE1 GAD1 0 0 213 237 1 1
BACE1 SLC25A5 305 0 0 320 1 1
BACE1 DNAJB11 0 0 75 168 1 1
BACE1 PLSCR1 213 0 540 622 1 1
BACE1 ATXN7L3B 0 0 206 221 1 1
BACE1 EFCAB11 0 0 81 190 1 1
BACE1 NFATC2 0 0 205 236 1 1
BACE1 EIF2S1 0 0 297 312 1 2
BACE1 HMOX1 0 0 325 341 1 2
BACE1 SLC17A7 0 0 274 305 1 1
BACE1 NRG1 0 0 683 717 1 2
BACE1 GLRX 0 0 90 154 1 1
BACE1 ASTL 0 0 81 175 1 1
BACE1 CD82 0 0 564 564 1 1
BACE1 DNMT3L 0 0 637 637 1 1
BACE1 BIN1 0 0 469 500 1 1
BACE1 FKBP6 0 0 0 212 1 1
BACE1 TGOLN2 0 0 233 260 1 1
BACE1 SPPL3 0 0 123 195 1 1
BACE1 GSTM4 0 0 0 170 1 1
BACE1 GTF2B 0 0 53 163 1 1
BACE1 DHCR24 0 0 285 300 1 1
BACE1 APLP2 0 0 681 759 1 1
BACE1 ADORA2B 0 0 163 163 1 1
BACE1 GAS2L3 0 0 0 171 1 1
BACE1 CPE 0 0 69 177 1 1
BACE1 SYNE2 0 0 0 171 1 1
BACE1 RSPO3 0 0 0 328 1 1
BACE1 GNAL 0 0 49 155 1 1
BACE1 CD4 0 0 212 218 1 2
BACE1 SYT4 0 0 148 190 1 1
BACE1 ATF4 0 0 279 279 1 2
BACE1 UBE3A 0 0 148 231 1 1
BACE1 PPARG 0 0 504 511 1 2
BACE1 TMED2 0 0 91 180 1 1
BACE1 AKT1 0 0 497 540 1 2
BACE1 CAPN1 0 0 211 217 1 2
BACE1 ARL5A 0 0 0 167 1 1
BACE1 CFH 0 0 231 273 1 1
BACE1 DISC1 0 0 310 309 1 1
BACE1 SPTB 0 0 108 219 1 1
BACE1 CELSR3 0 0 0 151 1 1
BACE1 DLG1 0 0 167 211 1 1
BACE1 GMFG 0 0 0 229 1 1
BACE1 PPP2R4 0 0 294 310 1 1
BACE1 GDI2 305 0 0 310 1 1
BACE1 ATF6 0 0 184 185 1 2
BACE1 GSTM1 0 0 75 187 1 1
BACE1 GAS2 0 0 0 171 1 1
BACE1 CXCL10 0 0 141 164 1 2
BACE1 SPON1 0 0 609 617 1 1
BACE1 RAB21 0 0 66 157 1 1
BACE1 CCK 0 0 180 262 1 1
BACE1 SIRT4 0 0 269 307 1 1
BACE1 DHRS2 0 0 62 150 1 1
BACE1 GSK3A 0 0 123 228 1 1
BACE1 ST6GAL1 0 0 463 463 1 1
BACE1 ADAM2 0 0 261 261 1 1
BACE1 TRIM2 0 0 107 187 1 1
BACE1 FBXO2 270 0 288 599 1 1
BACE1 ENSG00000274276 0 0 203 298 1 1
BACE1 ARG2 0 0 81 157 1 1
BACE1 ERBB2 0 0 246 385 1 2
BACE1 TSPAN5 0 0 162 265 1 1
BACE1 CTSC 0 0 85 300 1 1
BACE1 MDGA2 0 0 45 179 1 1
BACE1 VLDLR 0 0 342 373 1 1
BACE1 IGF2R 0 0 319 373 1 1
BACE1 DSTN 0 0 0 224 1 1
BACE1 ZMPSTE24 0 0 202 206 1 1
BACE1 CD9 0 0 183 208 1 1
BACE1 RSPO1 0 0 0 328 1 1
BACE1 RAB7A 0 0 369 426 1 2
BACE1 REST 0 0 233 252 1 2
BACE1 FKBP1C 0 0 81 175 1 1
BACE1 TFRC 0 0 770 779 1 1
BACE1 CACNG2 0 0 81 178 1 1
BACE1 IL1R2 0 0 167 219 1 1
BACE1 AGT 0 0 53 482 1 1
BACE1 TMPRSS2 0 0 0 248 1 1
BACE1 ATP12A 0 0 140 181 1 1
BACE1 GCG 0 0 210 210 1 1
BACE1 GSTP1 0 0 66 173 1 1
BACE1 TCP1 0 0 0 173 1 1
BACE1 ITIH4 0 0 161 179 1 1
BACE1 CST1 0 0 0 182 1 1
BACE1 MERTK 0 0 51 157 1 1
BACE1 SCN4A 0 0 85 161 1 1
BACE1 CNR1 0 0 184 183 1 1
BACE1 MEF2C 0 0 156 168 1 1
BACE1 ZFP36L2 0 0 0 166 1 1
BACE1 PLBD2 0 0 0 156 1 1
BACE1 MMP3 0 0 113 157 1 1
BACE1 SYT10 0 0 124 178 1 1
BACE1 TNF 0 0 458 480 1 2
BACE1 PTMA 0 0 61 274 1 1
BACE1 UQCRC1 0 0 45 180 1 1
BACE1 VPS11 270 0 0 291 1 1
BACE1 ABCA2 0 0 183 225 1 1
BACE1 FMR1 0 0 334 334 1 1
BACE1 STIP1 0 0 150 248 1 1
BACE1 RBFOX3 0 0 390 440 1 1
BACE1 EEF2 0 0 113 183 1 2
BACE1 ATXN7 0 0 214 214 1 1
BACE1 PPP1R15A 0 0 180 179 1 2
BACE1 RBM8A 0 0 181 189 1 1
BACE1 ATP13A2 0 0 208 230 1 1
BACE1 CES1 0 0 196 201 1 1
BACE1 ITM2C 213 0 539 621 1 1
BACE1 NAT8 0 900 282 925 1 1
BACE1 MS4A6A 0 0 292 292 1 1
BACE1 RCAN1 0 0 263 284 1 2
BACE1 FIS1 0 0 192 200 1 2
BACE1 EAPP 0 0 123 152 1 1
BACE1 SYN2 0 0 172 210 1 1
BACE1 PDCD6IP 0 0 141 180 1 1
BACE1 ALDH18A1 0 0 107 379 1 1
BACE1 CLSTN1 0 0 229 321 1 1
BACE1 RNASEL 0 0 0 192 1 1
BACE1 NFASC 0 0 169 382 1 1
BACE1 ZDHHC7 0 0 180 197 1 1
BACE1 ADH6 0 0 44 180 1 1
BACE1 PACS1 0 0 109 226 1 1
BACE1 PCSK2 0 0 45 256 1 1
BACE1 CAT 0 0 329 427 1 2
BACE1 PDPK1 0 0 108 159 1 2
BACE1 ENO4 0 0 0 164 1 1
BACE1 CANX 305 0 422 597 1 2
BACE1 GRIA1 0 0 370 392 1 1
BACE1 CCT6A 0 0 0 168 1 1
BACE1 CAST 0 0 202 202 1 2
BACE1 HRK 0 0 75 267 1 1
BACE1 STXBP3 0 0 0 200 1 1
BACE1 NTRK1 0 0 320 348 1 1
BACE1 LOX 0 0 130 151 1 2
BACE1 DRD1 0 0 134 154 1 1
BACE1 EGR2 0 0 124 165 1 1
BACE1 ENPP5 0 0 286 302 1 1
BACE1 KCNA1 0 0 134 193 1 1
BACE1 SAG 0 0 368 368 1 1
BACE1 HSPA9 0 0 61 214 1 1
BACE1 IRS1 0 0 294 294 1 2
BACE1 ADRB2 44 0 270 272 1 1
BACE1 AHCYL2 0 0 0 171 1 1
BACE1 EHD3 0 0 95 179 1 1
BACE1 PGC 0 0 138 154 1 1
BACE1 RPS6KB1 0 0 248 248 1 2
BACE1 IDUA 0 0 151 200 1 1
BACE1 NCOR1 0 0 95 170 1 1
BACE1 SREBF2 0 0 216 216 1 1
BACE1 EPHA1 0 0 283 311 1 1
BACE1 MICAL3 0 0 0 155 1 1
BACE1 ABCB5 0 0 0 188 1 1
BACE1 ABCG2 0 0 145 158 1 1
BACE1 CFI 0 0 357 357 1 1
BACE1 ADH5 0 0 0 177 1 1
BACE1 SPTBN5 0 0 0 160 1 1
BACE1 BCL2L2 0 0 107 192 1 1
BACE1 TTC28 0 0 0 152 1 1
BACE1 OGT 0 0 45 155 1 2
BACE1 TSPAN6 0 0 181 264 1 1
BACE1 SCN2B 0 0 412 424 1 1
BACE1 KCNA2 0 0 153 249 1 1
BACE1 APMAP 0 0 52 170 1 1
BACE1 GAD2 0 0 122 197 1 1
BACE1 IGF2 0 0 212 229 1 1
BACE1 AMPH 0 0 202 276 1 1
BACE1 M6PR 0 0 184 360 1 1
BACE1 RSPO4 0 0 0 328 1 1
BACE1 MAGED1 0 0 76 172 1 1
BACE1 IL10 0 0 270 270 1 2
BACE1 DLG4 0 0 601 627 1 2
BACE1 OPRD1 0 0 386 386 1 1
BACE1 DMD 0 0 72 170 1 2
BACE1 SMARCC2 0 0 0 156 1 1
BACE1 PPIL4 0 0 73 159 1 1
BACE1 C7orf34 0 0 203 212 1 1
BACE1 AGO1 0 0 122 188 1 1
BACE1 NME8 0 0 160 227 1 1
BACE1 CD200 0 0 306 306 1 1
BACE1 NFATC1 0 0 142 202 1 2
BACE1 AASDHPPT 0 0 635 638 1 1
BACE1 QDPR 0 0 47 263 1 1
BACE1 NTRK3 0 0 134 189 1 1
BACE1 FBXL2 0 0 125 208 1 1
BACE1 SLC9C2 0 0 0 189 1 1
BACE1 MMEL1 0 0 118 247 1 1
BACE1 CHL1 0 0 465 499 1 1
BACE1 SLC2A14 0 0 193 216 1 1
BACE1 CD79A 0 0 796 796 1 1
BACE1 NGFR 0 0 348 414 1 1
BACE1 KAT5 0 0 341 355 1 1
BACE1 CNTN2 0 0 524 543 1 1
BACE1 ACER1 0 0 0 161 1 1
BACE1 TACSTD2 0 0 48 153 1 1
BACE1 PDE10A 0 0 117 187 1 1
BACE1 ESR1 0 0 242 253 1 2
BACE1 UBQLN2 0 0 90 176 1 2
BACE1 SEZ6 0 0 391 495 1 1
BACE1 H2AFY 0 0 44 165 1 1
BACE1 TRAPPC5 305 0 0 317 1 1
BACE1 CDR1 0 0 181 211 1 1
BACE1 HOMER1 0 0 189 189 1 1
BACE1 EPPK1 0 0 0 171 1 1
BACE1 MBNL1 0 0 107 162 1 1
BACE1 NRD1 0 0 246 268 1 1
BACE1 KHK 0 0 450 450 1 1
BACE1 F9 0 0 46 162 1 1
BACE1 SMTNL1 0 0 0 210 1 1
BACE1 ZFAND2B 0 0 306 313 1 1
BACE1 SLC6A3 0 0 193 201 1 1
BACE1 TNFAIP2 0 0 63 165 1 1
BACE1 ATP4A 0 0 139 180 1 1
BACE1 AP4E1 0 0 97 215 1 1
BACE1 DPYSL3 0 0 57 156 1 1
BACE1 SYP 0 0 650 675 1 1
BACE1 PPT1 0 0 74 150 1 1
BACE1 PREP 0 0 166 167 1 1
BACE1 APBA3 0 0 241 263 1 1
BACE1 SARS 0 0 0 194 1 1
BACE1 SPHK1 0 0 276 290 1 2
BACE1 AGFG1 0 0 138 181 1 1
BACE1 UBC 0 0 67 162 1 2
BACE1 MAP1LC3B 0 0 173 213 1 2
BACE1 SPHK2 0 0 295 326 1 1
BACE1 ADRB1 0 0 181 181 1 1
BACE1 APBB3 0 0 245 244 1 1
BACE1 RAB3A 0 0 164 195 1 1
BACE1 NECAB3 0 0 0 207 1 1
BACE1 ADI1 0 0 233 244 1 1
BACE1 PPIL2 0 0 195 263 1 1
BACE1 TSG101 0 0 218 229 1 2
BACE1 SNX5 0 0 126 301 1 1
BACE1 C3 0 0 149 167 1 2
BACE1 FN1 0 0 211 239 1 2
BACE1 TBP 0 0 134 173 1 1
BACE1 GALNT13 0 0 48 167 1 1
BACE1 CRISP1 0 0 142 194 1 1
BACE1 ULK1 0 0 123 179 1 2
BACE1 MAP4 0 0 0 150 1 1
BACE1 CAMK2A 0 0 215 260 1 2
BACE1 PRKCA 0 0 91 165 1 1
BACE1 DST 0 0 0 228 1 2
BACE1 CA12 0 0 43 161 1 1
BACE1 PTH 0 0 90 186 1 1
BACE1 TKT 0 0 70 196 1 1
BACE1 KRAS 0 0 74 154 1 2
BACE1 PHF1 0 0 493 535 1 1
BACE1 SV2A 0 0 210 234 1 1
BACE1 CCT7 0 0 0 170 1 1
BACE1 MMP24 0 0 253 276 1 1
BACE1 AQP4 0 0 188 248 1 1
BACE1 GABBR1 0 0 155 184 1 1
BACE1 SIGMAR1 0 0 188 188 1 1
BACE1 SCN8A 0 0 234 308 1 1
BACE1 APBA2 0 0 370 401 1 1
BACE1 CCT6B 0 0 0 168 1 1
BACE1 CD81 0 0 244 245 1 1
BACE1 LRP1 213 0 669 747 1 1
BACE1 SNX4 0 0 205 205 1 2
BACE1 IL2 0 0 141 159 1 1
BACE1 PSENEN 0 0 838 859 1 1
BACE1 ABCB1 0 0 142 273 1 2
BACE1 ADHFE1 0 0 0 167 1 1
BACE1 CYB5R4 0 0 0 222 1 1
BACE1 BECN1 0 0 325 361 1 2
BACE1 MAPT 0 0 736 747 1 2
BACE1 EEF1G 0 0 0 161 1 1
BACE1 AP1S1 0 0 444 444 1 1
BACE1 ELAVL4 0 0 324 340 1 1
BACE1 HIST1H4G 0 0 240 268 1 1
BACE1 MFI2 0 0 113 196 1 1
BACE1 ATXN3 0 0 203 224 1 2
BACE1 DNAJC10 0 0 359 427 1 1
BACE1 APH1A 0 0 869 870 1 1
BACE1 TMPRSS15 0 0 195 214 1 1
BACE1 REN 0 0 325 173 1 1
BACE1 ASAH1 0 0 112 185 1 1
BACE1 VPS13A 0 0 66 152 1 1
BACE1 ACE 0 0 391 418 1 1
BACE1 CTSS 0 0 48 272 1 1
BACE1 ABCA7 0 0 469 476 1 1
BACE1 ENSG00000268643 0 0 0 155 1 1
BACE1 CNTN5 0 0 134 166 1 1
BACE1 GGA3 486 600 690 933 1 1
BACE1 PPME1 0 0 90 212 1 1
BACE1 CYBB 0 0 146 156 1 2
BACE1 HDAC9 0 0 71 178 1 1
BACE1 REL 0 0 142 168 1 2
BACE1 KLC1 0 0 145 261 1 1
BACE1 NLRP3 0 0 181 187 1 2
BACE1 CTSZ 0 0 94 307 1 1
BACE1 HCRT 0 0 166 165 1 1
BACE1 SLITRK1 0 0 126 207 1 1
BACE1 PSMG1 0 0 0 248 1 1
BACE1 PTGS2 0 0 391 434 1 2
BACE1 CASP3 0 0 518 539 1 2
BACE1 ERBB3 0 0 235 282 1 1
BACE1 SMPD1 0 0 234 250 1 1
BACE1 TXNRD1 0 0 51 239 1 1
BACE1 GPR126 0 0 108 199 1 1
BACE1 PPIAL4D 0 0 0 167 1 1
BACE1 SCN4B 0 0 203 265 1 1
BACE1 FLOT2 270 0 248 444 1 1
BACE1 PDIA4 0 0 74 170 1 1
BACE1 ABCB4 0 0 0 188 1 1
BACE1 ACO1 0 0 136 221 1 1
BACE1 TXNRD2 0 0 67 190 1 1
BACE1 TKTL2 0 0 0 171 1 1
BACE1 LRCH4 0 0 103 195 1 1
BACE1 GPX8 0 0 0 165 1 1
BACE1 ARRB1 0 0 138 157 1 1
BACE1 GRIN3A 0 0 69 223 1 1
BACE1 GSK3B 0 0 537 625 1 2
BACE1 TTR 0 0 299 321 1 1
BACE1 S100B 0 0 342 355 1 1
BACE1 ZFAND2A 0 0 306 313 1 1
BACE1 ARRB2 0 0 160 159 1 1
BACE1 CDKN2A 0 0 180 188 1 2
BACE1 GUSB 0 0 142 187 1 1
BACE1 RPS27A 0 0 0 165 1 1
BACE1 EPHB2 0 0 212 243 1 2
BACE1 NTF3 0 0 213 213 1 1
BACE1 APBB2 0 0 329 334 1 1
BACE1 AKAP3 0 0 0 157 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0001540 Molecular Function amyloid-beta binding enables IPI
GO:0004190 Molecular Function aspartic-type endopeptidase activity enables IDA
GO:0008798 Molecular Function beta-aspartyl-peptidase activity enables TAS
GO:0004175 Molecular Function endopeptidase activity enables IDA
GO:0019899 Molecular Function enzyme binding enables IPI
GO:0008233 Molecular Function peptidase activity enables IDA
GO:0005515 Molecular Function protein binding enables IPI
GO:1990000 Biological Process amyloid fibril formation involved_in TAS
GO:0042987 Biological Process amyloid precursor protein catabolic process involved_in ISS
GO:0034205 Biological Process amyloid-beta formation involved_in IDA
GO:0050435 Biological Process amyloid-beta metabolic process involved_in IBA
GO:0050435 Biological Process amyloid-beta metabolic process involved_in IDA
GO:1904646 Biological Process cellular response to amyloid-beta involved_in IEA
GO:0071280 Biological Process cellular response to copper ion involved_in IEA
GO:0071287 Biological Process cellular response to manganese ion involved_in IEA
GO:0050966 Biological Process detection of mechanical stimulus involved in sensory perception of pain involved_in IEA
GO:0006509 Biological Process membrane protein ectodomain proteolysis involved_in IBA
GO:0006509 Biological Process membrane protein ectodomain proteolysis involved_in IDA
GO:0006509 Biological Process membrane protein ectodomain proteolysis involved_in TAS
GO:0043525 Biological Process positive regulation of neuron apoptotic process involved_in IGI
GO:0060134 Biological Process prepulse inhibition involved_in IEA
GO:0099171 Biological Process presynaptic modulation of chemical synaptic transmission involved_in IEA
GO:0016485 Biological Process protein processing involved_in IDA
GO:0006508 Biological Process proteolysis involved_in IDA
GO:0010288 Biological Process response to lead ion involved_in IEA
GO:0140448 Biological Process signaling receptor ligand precursor processing involved_in IEA
GO:0005794 Cellular Component Golgi apparatus located_in IDA
GO:0070931 Cellular Component Golgi-associated vesicle lumen located_in TAS
GO:0030424 Cellular Component axon located_in IEA
GO:0009986 Cellular Component cell surface located_in IDA
GO:0009986 Cellular Component cell surface located_in ISS
GO:0030425 Cellular Component dendrite located_in IEA
GO:0005769 Cellular Component early endosome located_in IDA
GO:0005788 Cellular Component endoplasmic reticulum lumen located_in TAS
GO:0005768 Cellular Component endosome is_active_in IBA
GO:0005768 Cellular Component endosome located_in IDA
GO:0010008 Cellular Component endosome membrane located_in TAS
GO:0098686 Cellular Component hippocampal mossy fiber to CA3 synapse located_in IEA
GO:0005770 Cellular Component late endosome located_in IDA
GO:0005764 Cellular Component lysosome located_in IDA
GO:0016020 Cellular Component membrane located_in NAS
GO:0045121 Cellular Component membrane raft located_in IEA
GO:0005771 Cellular Component multivesicular body located_in IDA
GO:0043025 Cellular Component neuronal cell body located_in IEA
GO:0005886 Cellular Component plasma membrane is_active_in IBA
GO:0005886 Cellular Component plasma membrane located_in IDA
GO:0005886 Cellular Component plasma membrane located_in TAS
GO:0055037 Cellular Component recycling endosome located_in IDA
GO:0008021 Cellular Component synaptic vesicle located_in IEA
GO:0005802 Cellular Component trans-Golgi network is_active_in IBA
GO:0005802 Cellular Component trans-Golgi network located_in IDA
Pathways
Name DB ID
Metabolism of proteins Reactome R-HSA-392499
Amyloid fiber formation Reactome R-HSA-977225
Alzheimer's disease (WP5124) WikiPathways WP5124_r123917
Copper homeostasis (WP3286) WikiPathways WP3286_r106367
Inclusion body myositis (WP5120) WikiPathways WP5120_r120422
Alzheimer's disease and miRNA effects (WP2059) WikiPathways WP2059_r119468
DYRK1A (WP5180) WikiPathways WP5180_r122423
Transcripts
Accession Version MolecularType Name NCBI Comments
NM_138973 4 mRNA transcript variant d NC_000011 Reference
NM_138971 4 mRNA transcript variant c NC_000011 Reference
NM_138972 4 mRNA transcript variant b NC_000011 Reference
NM_012104 6 mRNA transcript variant a NC_000011 Reference
NM_001411039 1 mRNA transcript variant g NC_000011 Reference
NM_001207049 3 mRNA transcript variant f NC_000011 Reference
NM_001207048 3 mRNA transcript variant e NC_000011 Reference