CHMP2B

charged multivesicular body protein 2B
General Information
Name charged multivesicular body protein 2B
Alias
  • charged multivesicular body protein 2b
  • VPS2 homolog B
  • chromatin modifying protein 2B
  • vacuolar protein-sorting-associated protein 2-2
Synonyms DKFZP564O123 CHMP2.5 VPS2B ALS17 DMT1 FTDALS7 VPS2-2
Gene_family Charged multivesicular body proteins|ESCRT-III
organism Homo sapiens
entrez_id 25978
location 3p11.2
transcript_count 4
exon_count 7
Cross References
Location
by NCBI GRCh38.p14
    Summary
      Entrez This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration. [provided by RefSeq, Jul 2008]
      Stringdb Charged multivesicular body protein 2b; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential functio [...]
      nextProt Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4.
    Interactions
    NCBI
    A A.Source B B.DB B.Source Description PubMed
    CHMP2B BioGRID FMNL2 GeneID BioGRID Proximity Label-MS
    CHMP2B BioGRID IFTAP GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID HECTD1 GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID YAP1 GeneID BioGRID Affinity Capture-Western
    CHMP2B BioGRID VPS4B GeneID BioGRID Affinity Capture-Western
    CHMP2B BioGRID DLST GeneID BioGRID Cross-Linking-MS (XL-MS)
    CHMP2B BioGRID RPA4 GeneID BioGRID Proximity Label-MS
    CHMP2B BioGRID CFTR GeneID BioGRID PCA
    CHMP2B BioGRID Rab18 GeneID BioGRID Proximity Label-MS
    CHMP2B BioGRID N GeneID BioGRID Proximity Label-MS
    CHMP2B BioGRID Snd1 GeneID BioGRID Proximity Label-MS
    CHMP2B BioGRID KBTBD4 GeneID BioGRID Proximity Label-MS
    CHMP2B BioGRID STAU1 GeneID BioGRID Proximity Label-MS
    CHMP2B BioGRID RET GeneID BioGRID Proximity Label-MS
    CHMP2B BioGRID INSR GeneID BioGRID Proximity Label-MS
    CHMP2B BioGRID FGFR4 GeneID BioGRID Proximity Label-MS
    CHMP2B BioGRID EGFR GeneID BioGRID Proximity Label-MS
    CHMP2B BioGRID ORF1ab GeneID BioGRID Proximity Label-MS
    CHMP2B BioGRID ORF1ab GeneID BioGRID Proximity Label-MS
    CHMP2B BioGRID ORF1ab GeneID BioGRID Proximity Label-MS
    CHMP2B BioGRID ORF1ab GeneID BioGRID Proximity Label-MS
    CHMP2B BioGRID ORF1ab GeneID BioGRID Proximity Label-MS
    CHMP2B BioGRID HSPA1A GeneID BioGRID Proximity Label-MS
    CHMP2B BioGRID ZRANB1 GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID BAP1 GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID PRKN GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID CHMP4B GeneID BioGRID Affinity Capture-MS; Co-fractionation
    CHMP2B BioGRID CHMP4C GeneID BioGRID Co-fractionation
    CHMP2B BioGRID CHMP3 GeneID BioGRID Co-fractionation; Two-hybrid
    CHMP2B BioGRID CHMP5 GeneID BioGRID Co-fractionation
    CHMP2B BioGRID CHMP4A GeneID BioGRID Co-fractionation
    CHMP2B BioGRID CHMP2A GeneID BioGRID Co-fractionation
    CHMP2B BioGRID CHMP1A GeneID BioGRID Co-fractionation
    CHMP2B BioGRID HMGN2 GeneID BioGRID Co-fractionation
    CHMP2B BioGRID FOXA1 GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID CADPS GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID CLTA GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID IFITM3 GeneID BioGRID Proximity Label-MS
    CHMP2B BioGRID IFITM1 GeneID BioGRID Proximity Label-MS
    CHMP2B BioGRID NAA40 GeneID BioGRID Proximity Label-MS
    CHMP2B BioGRID SUV39H2 GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID ZBTB2 GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID VTA1 GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID BTF3 GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID TRIM36 GeneID BioGRID Proximity Label-MS
    CHMP2B BioGRID STX7 GeneID BioGRID Proximity Label-MS
    CHMP2B BioGRID SEC62 GeneID BioGRID Proximity Label-MS
    CHMP2B BioGRID LAMP1 GeneID BioGRID Proximity Label-MS
    CHMP2B BioGRID EMD GeneID BioGRID Proximity Label-MS
    CHMP2B BioGRID ACTB GeneID BioGRID Proximity Label-MS
    CHMP2B BioGRID COPS5 GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID Rnf183 GeneID BioGRID Proximity Label-MS
    CHMP2B BioGRID PLEKHG3 GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID FKBP8 GeneID BioGRID Proximity Label-MS
    CHMP2B BioGRID ATP5ME GeneID BioGRID Proximity Label-MS
    CHMP2B BioGRID ORF1ab GeneID BioGRID Two-hybrid
    CHMP2B BioGRID ORF1ab GeneID BioGRID Two-hybrid
    CHMP2B BioGRID PLEKHA4 GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID CGAS GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID ESR2 GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID TNIP2 GeneID BioGRID Affinity Capture-RNA
    CHMP2B BioGRID FBXO7 GeneID BioGRID Biochemical Activity
    CHMP2B BioGRID TMEM106B GeneID BioGRID Affinity Capture-Western; Co-localization
    CHMP2B BioGRID CDH1 GeneID BioGRID Proximity Label-MS
    CHMP2B BioGRID Nup98 GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID Ptpn23 GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID Rcc1 GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID Chmp4b GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID Cep55 GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID Ten1 GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID Eloc GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID Vps28 GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID Tipin GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID Spast GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID Papss1 GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID Tsg101 GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID Timeless GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID Vps4b GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID Rab5c GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID Jup GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID Cd2ap GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID C1qbp GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID Bub1 GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID Bmpr1a GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID SGO1 GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID MYH14 GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID GOLT1B GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID LTN1 GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID ATP6AP2 GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID RAB7A GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID XPO1 GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID RAB5C GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID MAD2L1 GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID PAFAH1B1 GeneID BioGRID Co-fractionation
    CHMP2B BioGRID ATP6V1B1 GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID MALSU1 GeneID BioGRID Two-hybrid
    CHMP2B BioGRID PHGDH GeneID BioGRID Two-hybrid
    CHMP2B BioGRID CHMP2B GeneID BioGRID Two-hybrid
    CHMP2B BioGRID PNMA1 GeneID BioGRID Two-hybrid
    CHMP2B BioGRID USP54 GeneID BioGRID Reconstituted Complex
    CHMP2B BioGRID TERF2IP GeneID BioGRID Two-hybrid
    CHMP2B BioGRID USP8 GeneID BioGRID Reconstituted Complex
    CHMP2B BioGRID SQSTM1 GeneID BioGRID Affinity Capture-Western
    CHMP2B Protein DPY30 GeneID HPRD None
    CHMP2B Protein CHMP3 GeneID HPRD None
    CHMP2B Protein CHMP2B GeneID HPRD None
    CHMP2B Protein MALSU1 GeneID HPRD None
    CHMP2B Protein PHGDH GeneID HPRD None
    CHMP2B Protein PNMA1 GeneID HPRD None
    CHMP2B Protein TRAF2 GeneID HPRD None
    CHMP2B Protein CENPF GeneID HPRD None
    CHMP2B Protein ATP5F1C GeneID HPRD None
    CHMP2B BioGRID ATP5F1C GeneID BioGRID Two-hybrid
    CHMP2B BioGRID VHL GeneID BioGRID Affinity Capture-MS
    CHMP2B BioGRID TRAF2 GeneID BioGRID Two-hybrid
    StringDB
    A B experiments database textmining combined score hadb nhadb
    CHMP2B SLC25A46 0 0 0 199 1 1
    CHMP2B RAB39B 0 0 251 274 1 2
    CHMP2B UEVLD 0 0 0 307 1 1
    CHMP2B HNRNPC 0 0 174 173 1 1
    CHMP2B ASB2 0 0 0 150 1 1
    CHMP2B DNAJC13 0 0 157 196 1 1
    CHMP2B DNM1 0 0 0 159 1 1
    CHMP2B FOXP2 0 0 81 180 1 1
    CHMP2B HSPA5 0 0 0 155 1 2
    CHMP2B RPF1 0 0 0 157 1 1
    CHMP2B CHMP5 0 600 564 978 1 1
    CHMP2B MLST8 0 0 57 160 1 2
    CHMP2B RABAC1 0 0 454 506 1 1
    CHMP2B PICALM 0 0 218 251 1 1
    CHMP2B SNX2 0 0 112 285 1 1
    CHMP2B GTF2F2 0 0 112 201 1 1
    CHMP2B ASB5 0 0 0 150 1 1
    CHMP2B OSBPL11 0 0 88 193 1 1
    CHMP2B RRAGC 0 0 61 316 1 1
    CHMP2B DEPTOR 0 0 74 173 1 1
    CHMP2B COPS6 0 0 0 204 1 1
    CHMP2B TVP23B 0 0 0 171 1 1
    CHMP2B ANKRD32 0 0 0 150 1 1
    CHMP2B MOBP 0 0 164 163 1 1
    CHMP2B JADE3 0 0 0 241 1 1
    CHMP2B ASB8 0 0 0 150 1 1
    CHMP2B GNAI3 0 0 75 212 1 2
    CHMP2B SIGMAR1 0 0 519 573 1 1
    CHMP2B RRAGD 0 0 0 205 1 1
    CHMP2B C16orf70 0 0 90 152 1 1
    CHMP2B CHCHD10 0 0 607 611 1 1
    CHMP2B ENSG00000260914 0 0 0 444 1 1
    CHMP2B VAC14 0 0 124 184 1 1
    CHMP2B CDKN2B 0 0 0 150 1 1
    CHMP2B TRIQK 0 0 261 261 1 1
    CHMP2B ANKRD45 0 0 0 155 1 1
    CHMP2B C3orf38 0 0 234 284 1 1
    CHMP2B LRRK2 0 0 454 488 1 2
    CHMP2B TM9SF2 0 0 0 155 1 1
    CHMP2B CDKN2C 0 0 0 150 1 1
    CHMP2B ATXN3 0 0 242 267 1 1
    CHMP2B NAPA 0 0 161 206 1 1
    CHMP2B CYB5R4 0 0 0 176 1 1
    CHMP2B BECN1 0 0 270 366 1 2
    CHMP2B MAPT 0 0 756 758 1 2
    CHMP2B SNX4 0 0 0 211 1 1
    CHMP2B ZNF654 0 0 270 282 1 1
    CHMP2B SEPT7 0 0 71 154 1 1
    CHMP2B CRYM 0 0 181 181 1 1
    CHMP2B ANKRD63 0 0 0 150 1 1
    CHMP2B ASZ1 0 0 0 150 1 1
    CHMP2B ANG 0 0 406 406 1 1
    CHMP2B HSPA4L 0 0 0 155 1 1
    CHMP2B ABCA7 0 0 212 212 1 1
    CHMP2B STX16 0 0 125 178 1 1
    CHMP2B COG7 0 0 90 260 1 1
    CHMP2B ATG12 0 0 170 195 1 2
    CHMP2B TONSL 0 0 0 150 1 1
    CHMP2B VPS13A 0 0 217 248 1 1
    CHMP2B TUBB6 0 900 0 900 1 1
    CHMP2B VPS29 0 0 125 196 1 1
    CHMP2B TUBB2B 0 900 0 901 1 1
    CHMP2B JADE1 0 0 67 401 1 1
    CHMP2B UFL1 0 0 57 184 1 1
    CHMP2B PLIN3 0 900 0 901 1 1
    CHMP2B COPS8 0 0 90 173 1 1
    CHMP2B HSPA1B 0 0 0 155 1 1
    CHMP2B HSPB8 0 0 124 196 1 2
    CHMP2B ATG101 0 0 182 215 1 2
    CHMP2B PLA2G6 0 0 209 209 1 1
    CHMP2B ATP5I 131 0 0 150 1 1
    CHMP2B HIGD1A 0 0 0 213 1 1
    CHMP2B LRCH4 0 0 75 350 1 1
    CHMP2B CDC123 0 0 61 317 1 1
    CHMP2B TUBA8 0 900 0 907 1 1
    CHMP2B RRM2 0 0 149 191 1 1
    CHMP2B FLOT2 0 0 0 152 1 1
    CHMP2B TMEM106B 270 0 774 852 1 1
    CHMP2B ATG16L1 0 0 148 166 1 2
    CHMP2B HAT1 0 0 0 160 1 1
    CHMP2B KIFAP3 0 0 202 202 1 1
    CHMP2B PFN1 0 0 372 410 1 1
    CHMP2B WNT2 0 0 170 169 1 1
    CHMP2B IQCA1 0 0 0 219 1 1
    CHMP2B ANKRD29 0 0 0 150 1 1
    CHMP2B STAM 0 900 279 939 1 1
    CHMP2B WDR41 0 0 391 454 1 2
    CHMP2B ANKS4B 0 0 0 150 1 1
    CHMP2B STAMBPL1 0 0 0 257 1 1
    CHMP2B CDKN2A 0 0 0 150 1 2
    CHMP2B RPS27A 0 600 0 618 1 1
    CHMP2B M6PR 0 0 201 205 1 1
    CHMP2B EIF3F 0 0 0 204 1 1
    CHMP2B CTSD 0 0 322 366 1 2
    CHMP2B PON2 0 0 167 224 1 1
    CHMP2B ANKRD18B 0 0 0 150 1 1
    CHMP2B VTI1B 0 0 157 247 1 2
    CHMP2B STX12 0 0 219 266 1 1
    CHMP2B BROX 0 0 138 156 1 1
    CHMP2B ATG7 0 0 358 474 1 2
    CHMP2B ANKRD20A3 0 0 0 150 1 1
    CHMP2B LRCH3 0 0 0 172 1 1
    CHMP2B NCK1 0 0 0 151 1 1
    CHMP2B HBB 0 900 0 900 1 1
    CHMP2B MATR3 0 0 519 582 1 1
    CHMP2B GABARAP 0 900 156 917 1 2
    CHMP2B RAB5C 131 0 60 218 1 1
    CHMP2B VPS26B 0 0 0 154 1 1
    CHMP2B TMEM229B 0 0 171 177 1 1
    CHMP2B ENOPH1 0 0 53 162 1 1
    CHMP2B SRP9 0 0 0 154 1 1
    CHMP2B SLC9C2 0 0 0 155 1 1
    CHMP2B WIPI1 0 0 180 228 1 2
    CHMP2B PANK2 0 0 150 168 1 1
    CHMP2B DNM1L 0 0 45 194 1 2
    CHMP2B PCMT1 0 0 90 190 1 1
    CHMP2B SMNDC1 0 0 0 191 1 1
    CHMP2B KIAA0226 0 0 140 173 1 1
    CHMP2B SIL1 0 0 0 150 1 1
    CHMP2B ATAD2B 0 0 0 242 1 1
    CHMP2B AMBRA1 0 0 174 175 1 2
    CHMP2B HFE 0 0 143 161 1 1
    CHMP2B GLE1 0 0 296 304 1 1
    CHMP2B NFKBIA 0 0 0 168 1 1
    CHMP2B UBA52 0 600 0 609 1 1
    CHMP2B SMCR8 0 0 421 433 1 2
    CHMP2B PJA2 0 0 0 190 1 1
    CHMP2B CTSB 0 0 136 177 1 2
    CHMP2B DPM1 0 0 0 232 1 1
    CHMP2B CGGBP1 0 0 126 187 1 1
    CHMP2B PLIN2 0 900 0 900 1 1
    CHMP2B SIRT1 0 0 90 153 1 2
    CHMP2B ENSG00000100926 0 0 45 514 1 1
    CHMP2B RAB22A 0 0 0 154 1 1
    CHMP2B OPTN 0 0 683 731 1 2
    CHMP2B UBQLN2 0 0 739 766 1 2
    CHMP2B BACE1 0 0 163 182 1 1
    CHMP2B COPS5 0 0 66 272 1 1
    CHMP2B IQCA1P1 0 0 0 219 1 1
    CHMP2B MAPK6 0 0 0 158 1 1
    CHMP2B ATAD1 0 0 0 267 1 1
    CHMP2B ATG5 0 0 294 424 1 2
    CHMP2B DYNC1H1 0 0 252 288 1 1
    CHMP2B ANKRD22 0 0 0 150 1 1
    CHMP2B TIA1 0 0 217 257 1 1
    CHMP2B C2orf43 0 0 210 210 1 1
    CHMP2B TANC2 0 0 0 150 1 1
    CHMP2B GBE1 0 0 202 231 1 1
    CHMP2B ASB3 0 0 0 150 1 1
    CHMP2B GPR88 0 0 82 400 1 1
    CHMP2B FUS 0 0 801 801 1 1
    CHMP2B UFM1 0 0 0 229 1 1
    CHMP2B ACTRT2 0 0 145 192 1 1
    CHMP2B MIB1 0 0 0 335 1 1
    CHMP2B ESPN 0 0 0 150 1 1
    CHMP2B ATG10 0 0 158 187 1 2
    CHMP2B TSG101 0 900 502 964 1 2
    CHMP2B ARL13B 0 900 0 905 1 1
    CHMP2B UBC 0 600 60 626 1 1
    CHMP2B BTBD1 0 0 0 187 1 1
    CHMP2B MAP1LC3B 0 900 150 921 1 2
    CHMP2B NFKBIB 0 0 0 150 1 1
    CHMP2B OSBPL8 0 0 74 201 1 1
    CHMP2B CHMP6 0 900 608 976 1 1
    CHMP2B IFT74 0 0 325 325 1 1
    CHMP2B RIPK4 0 0 0 150 1 1
    CHMP2B STX7 0 0 125 215 1 2
    CHMP2B ULK1 0 0 211 235 1 2
    CHMP2B PSMD14 0 0 0 246 1 1
    CHMP2B DYNLL2 0 0 96 177 1 1
    CHMP2B HNRNPDL 0 0 203 203 1 1
    CHMP2B LAMTOR3 0 0 0 325 1 1
    CHMP2B NFKB2 0 0 0 150 1 1
    CHMP2B RNFT2 0 0 0 199 1 1
    CHMP2B SDCBP 0 0 91 166 1 1
    CHMP2B CD2AP 0 0 108 230 1 1
    CHMP2B ASB11 0 0 0 150 1 1
    CHMP2B PLEKHA4 270 0 0 270 1 1
    CHMP2B GMFB 0 0 0 183 1 1
    CHMP2B ACTR6 0 0 0 173 1 1
    CHMP2B USP26 0 0 0 236 1 1
    CHMP2B ANKRD62 0 0 0 150 1 1
    CHMP2B RAB7A 131 0 573 681 1 2
    CHMP2B G3BP1 0 0 108 185 1 1
    CHMP2B DP2 0 0 0 189 1 1
    CHMP2B NEDD4L 0 600 44 609 1 1
    CHMP2B WDFY3 0 0 193 193 1 2
    CHMP2B CSF1R 0 0 202 214 1 1
    CHMP2B UVRAG 0 0 206 219 1 2
    CHMP2B SNF8 0 900 323 950 1 1
    CHMP2B CCDC144A 0 0 0 150 1 1
    CHMP2B HSPA2 0 0 0 155 1 1
    CHMP2B PAFAH1B1 272 0 0 272 1 1
    CHMP2B HSPA13 0 0 0 186 1 1
    CHMP2B TUBB4B 0 900 0 901 1 1
    CHMP2B ANKRD9 0 0 0 150 1 1
    CHMP2B DPP10 0 0 0 164 1 1
    CHMP2B ASB15 0 0 0 150 1 1
    CHMP2B NBR1 0 0 160 347 1 2
    CHMP2B RBM7 0 0 0 186 1 1
    CHMP2B VPS25 0 900 467 964 1 1
    CHMP2B DNAJC6 0 0 167 200 1 1
    CHMP2B PSMD6 0 0 0 155 1 1
    CHMP2B UNC13A 0 0 337 337 1 1
    CHMP2B VPS36 0 900 391 959 1 1
    CHMP2B ANKRD1 0 0 0 150 1 1
    CHMP2B BDNF 0 0 150 173 1 2
    CHMP2B TSNAX 0 0 0 160 1 1
    CHMP2B VAPB 0 0 681 721 1 1
    CHMP2B PON3 0 0 231 238 1 1
    CHMP2B WIPI2 0 0 157 212 1 2
    CHMP2B ATXN2L 0 0 0 206 1 1
    CHMP2B PNPLA6 0 0 257 311 1 1
    CHMP2B CHMP2A 272 900 852 990 1 2
    CHMP2B PDCD6IP 0 600 113 707 1 1
    CHMP2B ATP13A2 0 0 405 430 1 2
    CHMP2B ANKRD36 0 0 0 150 1 1
    CHMP2B PPP1R2 0 0 107 189 1 1
    CHMP2B POU2F1 0 0 46 318 1 1
    CHMP2B RBM8A 0 0 261 277 1 1
    CHMP2B ZFYVE26 0 0 181 187 1 1
    CHMP2B GBA 0 0 293 304 1 1
    CHMP2B PACS1 0 0 0 218 1 1
    CHMP2B ANKRD50 0 0 0 150 1 1
    CHMP2B CLN5 0 0 153 152 1 1
    CHMP2B TUBA1A 0 900 43 902 1 1
    CHMP2B SEP15 0 0 0 185 1 1
    CHMP2B ANKRD10 0 0 0 150 1 1
    CHMP2B SMN2 0 0 286 290 1 1
    CHMP2B MICU2 0 0 0 241 1 1
    CHMP2B MOB3A 0 0 0 189 1 1
    CHMP2B CHMP1A 0 800 764 983 1 1
    CHMP2B STXBP3 0 0 0 269 1 1
    CHMP2B NDUFB5 0 0 72 160 1 1
    CHMP2B INF2 0 0 0 171 1 1
    CHMP2B DEK 0 0 57 187 1 1
    CHMP2B UBB 0 600 0 619 1 1
    CHMP2B BARD1 0 0 0 150 1 1
    CHMP2B PDHB 0 0 108 612 1 1
    CHMP2B LEPREL2 0 0 212 212 1 1
    CHMP2B PPP2CA 0 0 0 165 1 1
    CHMP2B SPG11 0 0 593 607 1 1
    CHMP2B CRBN 0 0 63 163 1 1
    CHMP2B CHMP4B 682 900 805 997 1 2
    CHMP2B YWHAQ 0 0 283 327 1 1
    CHMP2B COG2 0 0 96 285 1 1
    CHMP2B STX8 0 0 145 204 1 2
    CHMP2B NUDT11 0 0 193 193 1 1
    CHMP2B ANKRD18A 0 0 0 150 1 1
    CHMP2B ACTR10 0 0 0 170 1 1
    CHMP2B HSPA9 0 0 0 173 1 1
    CHMP2B NTRK1 0 0 91 160 1 1
    CHMP2B EPG5 0 0 171 350 1 2
    CHMP2B POU1F1 0 0 427 470 1 1
    CHMP2B HNRNPA3 0 0 217 269 1 1
    CHMP2B VPS37B 0 900 248 945 1 1
    CHMP2B ANKRD37 0 0 0 150 1 1
    CHMP2B APEH 0 0 0 157 1 1
    CHMP2B NEK1 0 0 418 503 1 1
    CHMP2B ATXN2 0 0 561 606 1 1
    CHMP2B APOE 0 0 377 377 1 1
    CHMP2B RNPC3 0 0 0 159 1 1
    CHMP2B EEA1 0 0 211 237 1 1
    CHMP2B USP2 0 0 0 266 1 1
    CHMP2B IGHMBP2 0 0 166 170 1 1
    CHMP2B COMMD10 0 0 0 197 1 1
    CHMP2B DPY30 192 0 0 200 1 1
    CHMP2B HSPA12A 0 0 0 155 1 1
    CHMP2B SLK 0 0 0 183 1 1
    CHMP2B USP8 270 0 231 659 1 1
    CHMP2B TUBA1C 0 900 0 902 1 1
    CHMP2B CHMP7 0 900 561 965 1 1
    CHMP2B SORL1 0 0 324 341 1 1
    CHMP2B STAMBP 0 0 287 448 1 1
    CHMP2B MPHOSPH8 0 0 0 150 1 1
    CHMP2B PSMD7 0 0 0 204 1 1
    CHMP2B DAO 0 0 218 358 1 1
    CHMP2B TXNDC9 0 0 0 170 1 1
    CHMP2B ATG3 0 0 145 219 1 2
    CHMP2B ANKRD17 0 0 0 153 1 1
    CHMP2B ASB9 0 0 0 150 1 1
    CHMP2B TUBB8 0 900 0 901 1 1
    CHMP2B TUBB8B 0 900 0 901 1 1
    CHMP2B EWSR1 0 0 322 326 1 1
    CHMP2B TERF2IP 295 0 0 295 1 1
    CHMP2B POU4F1 0 0 51 197 1 1
    CHMP2B TBK1 0 0 564 657 1 2
    CHMP2B SEC13 0 0 0 153 1 1
    CHMP2B CHMP4A 0 900 818 989 1 1
    CHMP2B DYNLRB1 0 0 87 188 1 1
    CHMP2B TUBB2A 0 900 0 901 1 1
    CHMP2B BIN1 0 0 210 241 1 1
    CHMP2B SLC17A7 0 0 87 179 1 1
    CHMP2B SORCS1 0 0 157 179 1 1
    CHMP2B LRCH2 0 0 0 156 1 1
    CHMP2B RAB11A 0 0 234 348 1 1
    CHMP2B STX17 0 0 134 194 1 2
    CHMP2B UBA3 0 0 60 316 1 1
    CHMP2B HRH4 0 0 0 187 1 1
    CHMP2B RAB7B 0 0 458 495 1 1
    CHMP2B ATP5C1 72 0 0 229 1 1
    CHMP2B GORASP1 0 0 66 335 1 1
    CHMP2B VPS37D 0 900 241 935 1 1
    CHMP2B GHITM 0 0 58 153 1 1
    CHMP2B VAMP7 0 0 66 382 1 1
    CHMP2B IFT88 0 900 0 900 1 1
    CHMP2B DPP8 0 0 0 157 1 1
    CHMP2B ZFYVE1 0 0 139 259 1 2
    CHMP2B TMEM68 0 0 58 189 1 1
    CHMP2B SETX 0 0 600 617 1 1
    CHMP2B ARL5A 0 0 0 153 1 1
    CHMP2B IMPA1 0 0 81 173 1 1
    CHMP2B ATF1 0 0 0 166 1 1
    CHMP2B NUDT12 0 0 0 156 1 1
    CHMP2B HSPH1 0 0 0 155 1 1
    CHMP2B RRM1 0 0 170 194 1 1
    CHMP2B ALS2 0 0 681 759 1 1
    CHMP2B SNRPB2 0 0 73 238 1 1
    CHMP2B SYNJ2 0 0 171 189 1 1
    CHMP2B ANKRD30B 0 0 0 150 1 1
    CHMP2B LRCH1 0 0 0 174 1 1
    CHMP2B NIPA1 0 0 249 293 1 1
    CHMP2B NTRK2 0 0 127 173 1 1
    CHMP2B PSMD8 0 0 0 174 1 1
    CHMP2B SPATA5 0 0 0 230 1 1
    CHMP2B SPATA31E1 0 0 285 284 1 1
    CHMP2B SPATA5L1 0 0 0 230 1 1
    CHMP2B ANKS6 0 0 0 150 1 1
    CHMP2B ARF4 0 0 0 165 1 1
    CHMP2B AP1S2 0 0 73 159 1 1
    CHMP2B NVL 0 0 0 219 1 1
    CHMP2B UBQLN1 0 0 193 515 1 2
    CHMP2B PINK1 0 0 330 345 1 2
    CHMP2B VPS37A 0 900 246 935 1 1
    CHMP2B NDUFB6 0 0 45 433 1 1
    CHMP2B PHGDH 192 0 64 285 1 1
    CHMP2B RAB21 0 0 55 266 1 1
    CHMP2B CETN1 0 900 0 903 1 1
    CHMP2B PIKFYVE 0 0 203 257 1 1
    CHMP2B DMRTC2 0 0 235 235 1 1
    CHMP2B PEX6 0 0 0 219 1 1
    CHMP2B PTPN23 0 0 268 399 1 1
    CHMP2B DLD 0 0 134 277 1 1
    CHMP2B ANKRD6 0 0 0 150 1 1
    CHMP2B ATP6V1A 129 0 57 217 1 1
    CHMP2B YME1L1 0 0 0 195 1 1
    CHMP2B ITM2B 0 0 324 349 1 1
    CHMP2B KLHL33 0 0 161 161 1 1
    CHMP2B ASB14 0 0 0 150 1 1
    CHMP2B TMED5 0 0 0 331 1 1
    CHMP2B CTSC 0 0 157 177 1 1
    CHMP2B VTI1A 0 0 194 331 1 1
    CHMP2B TUBAL3 0 900 0 900 1 1
    CHMP2B RBFOX1 0 0 74 173 1 1
    CHMP2B TREM2 0 0 492 491 1 1
    CHMP2B VTA1 0 600 457 863 1 1
    CHMP2B MFN1 0 0 0 159 1 1
    CHMP2B TMEM106A 0 0 142 249 1 1
    CHMP2B UCHL1 0 0 134 167 1 1
    CHMP2B ESPNL 0 0 0 150 1 1
    CHMP2B USP50 0 0 0 236 1 1
    CHMP2B ANKHD1 0 0 0 177 1 1
    CHMP2B MIB2 0 0 0 374 1 1
    CHMP2B SOD1 0 0 634 739 1 1
    CHMP2B USH1G 0 0 0 150 1 1
    CHMP2B ANKRD36C 0 0 0 150 1 1
    CHMP2B ANKRD44 0 0 0 153 1 1
    CHMP2B NFKBIE 0 0 0 150 1 1
    CHMP2B ANKRD36B 0 0 0 150 1 1
    CHMP2B ELP3 0 0 335 344 1 1
    CHMP2B GRN 0 0 805 806 1 1
    CHMP2B ASB16 0 0 0 150 1 1
    CHMP2B IFNK 0 0 160 217 1 1
    CHMP2B VCP 0 0 856 931 1 2
    CHMP2B CEP55 0 0 282 356 1 1
    CHMP2B LAMP2 0 0 325 416 1 2
    CHMP2B ASB13 0 0 0 150 1 1
    CHMP2B COPE 0 0 67 175 1 1
    CHMP2B HNRNPA1 0 0 422 448 1 1
    CHMP2B DPP9 0 0 0 157 1 1
    CHMP2B VPS37C 0 900 212 932 1 1
    CHMP2B LEMD2 0 600 0 600 1 1
    CHMP2B AMFR 0 0 43 279 1 1
    CHMP2B FAM19A4 0 0 0 187 1 1
    CHMP2B ERBB4 0 0 235 263 1 1
    CHMP2B HSPA1A 0 0 0 155 1 1
    CHMP2B SNAP29 0 0 134 468 1 2
    CHMP2B NPC2 0 0 151 186 1 1
    CHMP2B SNCA 0 0 506 506 1 2
    CHMP2B GORASP2 0 0 124 269 1 1
    CHMP2B INA 0 0 166 165 1 1
    CHMP2B MALSU1 192 0 0 192 1 1
    CHMP2B SQSTM1 270 0 664 813 1 2
    CHMP2B GLI3 0 0 181 195 1 1
    CHMP2B CRYZ 0 0 45 191 1 1
    CHMP2B MPND 0 0 0 204 1 1
    CHMP2B BRCC3 0 0 0 204 1 1
    CHMP2B CNIH1 0 0 0 183 1 1
    CHMP2B SUB1 0 0 0 170 1 1
    CHMP2B LRRN1 0 0 81 356 1 1
    CHMP2B STUB1 0 0 74 234 1 2
    CHMP2B SPG7 0 0 139 189 1 1
    CHMP2B NEFH 0 0 424 475 1 1
    CHMP2B ATG13 0 0 217 249 1 2
    CHMP2B RANGAP1 0 0 113 249 1 1
    CHMP2B MMADHC 0 0 0 252 1 1
    CHMP2B VPS13C 0 0 175 208 1 1
    CHMP2B PDCD10 0 0 0 183 1 1
    CHMP2B PSEN1 0 0 518 531 1 2
    CHMP2B RAB29 0 0 141 164 1 1
    CHMP2B TOR1B 0 0 0 151 1 1
    CHMP2B ANKHD1-EIF4EBP3 0 0 0 150 1 1
    CHMP2B ANKRD2 0 0 0 150 1 1
    CHMP2B UFD1L 0 0 49 161 1 1
    CHMP2B HSP90AA1 0 0 108 161 1 2
    CHMP2B SPG20 0 0 86 174 1 1
    CHMP2B BCL3 0 0 0 150 1 1
    CHMP2B TFEB 0 0 292 300 1 2
    CHMP2B DPP6 0 0 242 344 1 1
    CHMP2B KIF5A 0 0 193 198 1 1
    CHMP2B GABARAPL1 0 900 212 923 1 2
    CHMP2B VPS16 0 0 134 176 1 1
    CHMP2B TUBA1B 0 900 0 902 1 1
    CHMP2B GIGYF2 0 0 334 362 1 1
    CHMP2B UBAP1 0 900 391 941 1 1
    CHMP2B TMEM175 0 0 251 252 1 1
    CHMP2B ZBTB7B 0 0 0 181 1 1
    CHMP2B MLKL 0 600 46 614 1 1
    CHMP2B RAB1A 0 0 151 259 1 2
    CHMP2B KCTD14 0 0 284 413 1 1
    CHMP2B UBE2N 0 0 73 290 1 1
    CHMP2B STX6 0 0 173 200 1 1
    CHMP2B TARDBP 0 0 745 790 1 1
    CHMP2B AP5Z1 0 0 144 182 1 1
    CHMP2B EIF4G1 0 0 203 215 1 2
    CHMP2B RSL24D1 0 0 0 170 1 1
    CHMP2B SUCLA2 0 0 0 170 1 1
    CHMP2B HSPA8 0 900 142 921 1 2
    CHMP2B GSR 0 0 0 169 1 1
    CHMP2B ENSG00000249884 0 900 764 950 1 1
    CHMP2B HNRNPH1 0 0 113 150 1 1
    CHMP2B ATG9A 0 0 185 264 1 2
    CHMP2B VPS28 0 900 455 964 1 1
    CHMP2B VPS35 0 0 391 453 1 1
    CHMP2B PTRHD1 0 0 150 169 1 1
    CHMP2B C21orf2 0 0 258 372 1 1
    CHMP2B DDX55 0 0 134 241 1 1
    CHMP2B VPS26A 0 0 151 382 1 1
    CHMP2B KDM8 0 0 0 208 1 1
    CHMP2B IL17RD 0 0 54 569 1 1
    CHMP2B EPHA4 0 0 143 170 1 1
    CHMP2B HYOU1 0 0 0 155 1 1
    CHMP2B HSPA14 0 0 0 192 1 1
    CHMP2B NEFL 0 0 202 216 1 1
    CHMP2B DNM2 0 0 0 164 1 1
    CHMP2B SPAST 0 600 423 814 1 1
    CHMP2B MAP1LC3C 0 900 0 906 1 2
    CHMP2B INVS 0 0 0 150 1 1
    CHMP2B CHMP3 644 900 827 981 1 1
    CHMP2B PPP1CB 0 0 94 224 1 1
    CHMP2B DCTN1 0 0 650 656 1 1
    CHMP2B DPP4 0 0 0 159 1 1
    CHMP2B VPS54 0 0 325 442 1 1
    CHMP2B TBC1D2 0 0 62 172 1 1
    CHMP2B LGALS4 0 0 148 166 1 1
    CHMP2B ENSG00000269905 0 0 0 189 1 1
    CHMP2B ASB12 0 0 0 150 1 1
    CHMP2B UCHL3 0 0 0 155 1 1
    CHMP2B FLOT1 0 0 183 276 1 1
    CHMP2B FAP 0 0 0 159 1 1
    CHMP2B PNMA1 192 0 0 192 1 1
    CHMP2B ERI1 0 0 0 186 1 1
    CHMP2B CSNK1D 0 0 228 247 1 1
    CHMP2B TYROBP 0 0 215 215 1 1
    CHMP2B ALB 0 0 112 158 1 1
    CHMP2B SORCS3 0 0 99 171 1 1
    CHMP2B MITD1 0 0 166 337 1 1
    CHMP2B SEC23B 0 0 0 176 1 2
    CHMP2B NAIF1 0 0 55 227 1 1
    CHMP2B SNCAIP 0 0 55 162 1 2
    CHMP2B LRRC47 0 0 135 158 1 1
    CHMP2B ANKRD54 0 0 0 150 1 1
    CHMP2B MADD 0 0 337 337 1 1
    CHMP2B SS18L1 0 0 261 291 1 1
    CHMP2B ANKRD55 0 0 0 150 1 1
    CHMP2B PRMT3 0 0 0 162 1 1
    CHMP2B NPM3 0 0 210 268 1 1
    CHMP2B ELMO1 0 0 46 170 1 1
    CHMP2B NOTCH3 0 0 195 195 1 1
    CHMP2B PLD3 0 0 95 157 1 1
    CHMP2B COQ2 0 0 122 157 1 1
    CHMP2B GAK 0 0 135 197 1 1
    CHMP2B ARL11 0 0 218 708 1 1
    CHMP2B ETS1 0 0 0 189 1 1
    CHMP2B SLC1A2 0 0 183 197 1 1
    CHMP2B FLCN 0 0 63 383 1 1
    CHMP2B TBC1D15 0 0 0 160 1 1
    CHMP2B SHOC2 0 0 0 157 1 1
    CHMP2B ANKRD66 0 0 0 150 1 1
    CHMP2B HIF1AN 0 0 88 654 1 1
    CHMP2B FBXO7 270 0 207 407 1 2
    CHMP2B LIN7C 0 0 0 167 1 1
    CHMP2B ANKRD39 0 0 0 150 1 1
    CHMP2B HSPA4 0 0 112 217 1 1
    CHMP2B FIGN 0 0 0 219 1 1
    CHMP2B TRIP13 0 0 0 219 1 1
    CHMP2B TMX1 0 0 0 153 1 1
    CHMP2B ATP6AP2 190 0 74 328 1 1
    CHMP2B USP29 0 0 0 236 1 1
    CHMP2B SEC23A 0 0 0 176 1 2
    CHMP2B ASB10 0 0 0 150 1 1
    CHMP2B MAP1S 0 0 82 196 1 2
    CHMP2B HNRNPA2B1 0 0 375 416 1 1
    CHMP2B MX2 0 0 0 159 1 1
    CHMP2B PRNP 0 0 391 438 1 1
    CHMP2B SCFD1 0 0 74 211 1 1
    CHMP2B CLVS1 0 0 146 339 1 1
    CHMP2B RHPN2 0 0 0 173 1 1
    CHMP2B HSPA6 0 0 0 155 1 1
    CHMP2B ANKRD30A 0 0 0 150 1 1
    CHMP2B VPS33A 0 0 95 159 1 1
    CHMP2B CAPZA2 0 0 0 185 1 1
    CHMP2B RAB38 0 0 292 292 1 1
    CHMP2B SHANK2 0 0 0 150 1 1
    CHMP2B CENPF 192 0 0 208 1 1
    CHMP2B REEP1 0 0 142 151 1 1
    CHMP2B RUFY1 0 0 0 205 1 1
    CHMP2B SHANK1 0 0 0 150 1 1
    CHMP2B ANKRD7 0 0 0 150 1 1
    CHMP2B PARK7 0 900 334 932 1 1
    CHMP2B GOLPH3 0 0 77 155 1 1
    CHMP2B VPS39 0 0 125 167 1 1
    CHMP2B C9orf72 0 0 833 858 1 2
    CHMP2B ANKRD16 0 0 0 150 1 1
    CHMP2B SMAD4 0 0 0 152 1 1
    CHMP2B ASB4 0 0 0 150 1 1
    CHMP2B MKNK2 0 0 55 161 1 1
    CHMP2B SYNJ1 0 0 218 235 1 1
    CHMP2B FKBP7 0 0 56 394 1 1
    CHMP2B PEX1 0 0 0 219 1 1
    CHMP2B OPA1 0 0 0 162 1 1
    CHMP2B PCNT 0 900 0 900 1 1
    CHMP2B CDKN2D 0 0 0 150 1 1
    CHMP2B CAB39 0 0 54 198 1 1
    CHMP2B VGLL3 0 0 517 774 1 1
    CHMP2B RB1CC1 0 0 209 389 1 2
    CHMP2B MARCH7 0 0 0 232 1 1
    CHMP2B NFE2L2 0 0 47 186 1 1
    CHMP2B SERINC1 0 0 61 217 1 1
    CHMP2B PLEKHA5 0 0 108 232 1 1
    CHMP2B UBE2K 0 0 0 159 1 1
    CHMP2B AZI2 0 0 0 151 1 1
    CHMP2B SCARB2 0 0 167 167 1 1
    CHMP2B HPSE 0 0 151 150 1 1
    CHMP2B ANKRD20A4 0 0 0 150 1 1
    CHMP2B ANKRD28 0 0 0 150 1 1
    CHMP2B ARL8B 0 0 54 323 1 1
    CHMP2B CHMP4C 0 600 503 887 1 1
    CHMP2B PARK2 0 0 393 403 1 1
    CHMP2B PURA 0 0 112 203 1 1
    CHMP2B NCSTN 0 0 75 159 1 1
    CHMP2B MAD2L1 218 0 0 235 1 1
    CHMP2B ST3GAL4 0 0 58 184 1 1
    CHMP2B VAPA 0 0 50 456 1 1
    CHMP2B SYT11 0 0 132 151 1 1
    CHMP2B TPI1 0 0 90 159 1 1
    CHMP2B MOB4 0 0 0 202 1 1
    CHMP2B HSPBAP1 0 0 0 208 1 1
    CHMP2B FBXO47 0 0 141 164 1 1
    CHMP2B CCDC3 0 0 117 358 1 1
    CHMP2B AP5M1 0 0 0 167 1 1
    CHMP2B LMBRD1 0 0 111 258 1 1
    CHMP2B MX1 0 0 0 159 1 1
    CHMP2B NPC1 0 0 142 224 1 2
    CHMP2B FANK1 0 0 0 150 1 1
    CHMP2B ERMP1 0 0 151 157 1 1
    CHMP2B ARHGEF28 0 0 268 343 1 1
    CHMP2B TUBA3E 0 900 0 902 1 1
    CHMP2B CALM3 0 0 175 207 1 1
    CHMP2B CLU 0 0 136 154 1 2
    CHMP2B SCOC 0 0 0 154 1 2
    CHMP2B PSMD10 0 0 0 196 1 1
    CHMP2B ANKRD42 0 0 0 150 1 1
    CHMP2B ANKRD30BL 0 0 0 150 1 1
    CHMP2B ZFYVE19 0 0 0 175 1 1
    CHMP2B HGS 0 900 281 935 1 2
    CHMP2B HSPA12B 0 0 0 155 1 1
    CHMP2B VAMP8 0 0 167 221 1 2
    CHMP2B ASB6 0 0 0 150 1 1
    CHMP2B LTN1 131 0 0 178 1 1
    CHMP2B HDAC6 0 900 218 922 1 2
    CHMP2B G3BP2 0 0 0 239 1 1
    CHMP2B CD300C 0 0 170 169 1 1
    CHMP2B GDNF 0 0 112 258 1 1
    CHMP2B TYW5 0 0 0 208 1 1
    CHMP2B HNRNPH2 0 0 134 170 1 1
    CHMP2B RAB9A 0 0 0 173 1 2
    CHMP2B SPTLC1 0 0 141 227 1 1
    CHMP2B ASB1 0 0 0 150 1 1
    CHMP2B TRIM23 0 0 0 254 1 1
    CHMP2B MCOLN1 0 0 162 161 1 1
    CHMP2B RAB8A 0 0 251 297 1 2
    CHMP2B MVB12A 0 900 123 914 1 1
    CHMP2B RHPN1 0 0 0 173 1 1
    CHMP2B LAMP1 0 0 367 456 1 2
    CHMP2B ANKFY1 0 0 0 150 1 1
    CHMP2B PPP1CC 0 0 59 160 1 1
    CHMP2B HTT 0 0 342 410 1 1
    CHMP2B TOR1A 0 0 0 256 1 1
    CHMP2B MYH14 190 0 0 203 1 1
    CHMP2B TUBA4A 0 900 391 938 1 1
    CHMP2B PCDH13 0 0 74 326 1 1
    CHMP2B KIF5C 0 0 112 173 1 1
    CHMP2B BNIP2 0 0 0 183 1 1
    CHMP2B ENSG00000273637 0 0 0 302 1 1
    CHMP2B USP37 0 0 0 236 1 1
    CHMP2B COMMD8 0 0 0 201 1 1
    CHMP2B CFTR 0 900 124 909 1 1
    CHMP2B VPS4B 878 600 880 996 1 1
    CHMP2B NFKBIZ 0 0 0 150 1 1
    CHMP2B MAP1A 0 0 108 170 1 1
    CHMP2B SNAP23 0 0 0 193 1 1
    CHMP2B USP54 270 0 0 317 1 1
    CHMP2B MOB3B 0 0 242 377 1 1
    CHMP2B RMDN3 0 0 143 201 1 1
    CHMP2B SGOL1 218 0 0 218 1 1
    CHMP2B KCNJ14 0 0 101 415 1 1
    CHMP2B CC2D1B 0 600 96 639 1 1
    CHMP2B MTOR 0 0 161 199 1 2
    CHMP2B ANKS3 0 0 0 150 1 1
    CHMP2B SORT1 0 0 255 290 1 1
    CHMP2B PSMC6 0 0 0 214 1 1
    CHMP2B ANKRD52 0 0 0 150 1 1
    CHMP2B PSEN2 0 0 556 560 1 1
    CHMP2B DR1 0 0 0 223 1 1
    CHMP2B USP21 0 0 0 266 1 1
    CHMP2B TRAPPC8 0 0 0 151 1 1
    CHMP2B NANS 0 0 96 234 1 1
    CHMP2B CCNC 0 0 0 199 1 1
    CHMP2B FIGNL1 0 0 73 245 1 1
    CHMP2B RNASE1 0 900 0 900 1 1
    CHMP2B VPS4A 417 600 814 972 1 1
    CHMP2B ENSG00000115239 0 0 0 150 1 1
    CHMP2B CCNF 0 0 231 230 1 1
    CHMP2B SMN1 0 0 261 261 1 1
    CHMP2B UBAP1L 0 540 0 540 1 1
    CHMP2B PIK3C3 0 0 218 258 1 2
    CHMP2B PPP1R12A 0 0 0 182 1 1
    CHMP2B MYSM1 0 0 0 204 1 1
    CHMP2B SNRPA 0 0 0 175 1 1
    CHMP2B MTMR6 0 0 0 185 1 1
    CHMP2B ATXN1 0 0 144 197 1 1
    CHMP2B NFKBID 0 0 0 150 1 1
    CHMP2B YPEL5 0 0 0 165 1 1
    CHMP2B BAG3 0 0 151 179 1 2
    CHMP2B RAB5A 0 0 324 472 1 2
    CHMP2B NAE1 0 0 56 199 1 1
    CHMP2B CMPK1 0 0 0 167 1 1
    CHMP2B ANKRD23 0 0 0 150 1 1
    CHMP2B PSMC2 0 0 0 252 1 1
    CHMP2B ASB18 0 0 0 150 1 1
    CHMP2B CLINT1 0 0 0 163 1 1
    CHMP2B GOLT1B 128 0 0 197 1 1
    CHMP2B FGGY 0 0 341 366 1 1
    CHMP2B RNFT1 0 0 0 199 1 1
    CHMP2B DNM3 0 0 0 159 1 1
    CHMP2B MVB12B 0 900 81 910 1 1
    CHMP2B INPP5B 0 0 193 210 1 1
    CHMP2B CLVS2 0 0 0 151 1 1
    CHMP2B MAP1LC3A 0 900 75 917 1 2
    CHMP2B MFN2 0 0 74 188 1 2
    CHMP2B APP 0 0 470 492 1 1
    CHMP2B PCDH20 0 0 74 326 1 1
    CHMP2B NFKB1 0 0 0 150 1 1
    CHMP2B LINGO2 0 0 122 684 1 1
    CHMP2B TUBB4A 0 900 46 901 1 1
    CHMP2B FYCO1 0 0 203 226 1 2
    CHMP2B PIK3R4 0 0 184 211 1 2
    CHMP2B ITPR2 0 0 193 217 1 1
    CHMP2B JADE2 0 0 0 190 1 1
    CHMP2B GABARAPL2 0 900 213 923 1 2
    CHMP2B TMEM106C 0 0 213 350 1 1
    CHMP2B CENPV 0 0 94 250 1 1
    CHMP2B KIF1A 0 0 122 182 1 1
    CHMP2B MAP6 0 0 310 315 1 1
    CHMP2B CHMP1B 0 900 561 991 1 1
    CHMP2B TMED7 0 0 0 325 1 1
    CHMP2B ATG14 0 0 211 273 1 2
    CHMP2B NDNF 0 0 97 433 1 1
    CHMP2B TUBB1 0 900 65 905 1 1
    CHMP2B NSF 0 0 0 219 1 1
    CHMP2B UBQLN4 0 0 50 299 1 2
    CHMP2B STAG2 0 0 0 159 1 1
    CHMP2B PCNP 0 0 0 317 1 1
    CHMP2B UBE2D3 0 0 0 157 1 1
    CHMP2B TAF15 0 0 341 368 1 1
    CHMP2B STAM2 0 720 103 793 1 1
    CHMP2B LRSAM1 0 0 134 389 1 2
    CHMP2B HSPA1L 0 0 0 155 1 1
    CHMP2B ATP1A3 0 0 108 156 1 1
    CHMP2B FIG4 0 0 681 752 1 1
    CHMP2B ANKRD20A1 0 0 0 150 1 1
    CHMP2B ZKSCAN3 0 0 172 186 1 2
    CHMP2B PSAP 0 0 218 288 1 1
    CHMP2B SERPINI1 0 0 195 195 1 1
    CHMP2B AEBP2 0 0 66 193 1 1
    CHMP2B TANC1 0 0 0 150 1 1
    CHMP2B USP43 0 0 0 253 1 1
    CHMP2B IST1 0 600 561 902 1 1
    CHMP2B KCNAB3 0 0 181 249 1 1
    CHMP2B ANKRD20A2 0 0 0 150 1 1
    CHMP2B FBXO32 0 0 202 251 1 2
    Ontologies
    ID Category Term Effect Evidence PubMed
    GO:0045296 Molecular Function cadherin binding enables HDA
    GO:0005515 Molecular Function protein binding enables IPI
    GO:0019904 Molecular Function protein domain specific binding enables IPI
    GO:1904903 Biological Process ESCRT III complex disassembly involved_in NAS
    GO:0097352 Biological Process autophagosome maturation involved_in IMP
    GO:0006914 Biological Process autophagy involved_in IMP
    GO:0006914 Biological Process autophagy involved_in TAS
    GO:0050890 Biological Process cognition involved_in IMP
    GO:0007032 Biological Process endosome organization involved_in IMP
    GO:0032509 Biological Process endosome transport via multivesicular body sorting pathway involved_in IBA
    GO:1902774 Biological Process late endosome to lysosome transport involved_in IMP
    GO:0045324 Biological Process late endosome to vacuole transport involved_in IBA
    GO:0016236 Biological Process macroautophagy involved_in TAS
    GO:0090148 Biological Process membrane fission involved_in NAS
    GO:0061952 Biological Process midbody abscission involved_in IMP
    GO:0007080 Biological Process mitotic metaphase chromosome alignment involved_in IMP
    GO:0050804 Biological Process modulation of chemical synaptic transmission involved_in IEA
    GO:0036258 Biological Process multivesicular body assembly involved_in NAS
    GO:0036258 Biological Process multivesicular body assembly involved_in TAS
    GO:0071985 Biological Process multivesicular body sorting pathway involved_in IDA
    GO:0061763 Biological Process multivesicular body-lysosome fusion involved_in NAS
    GO:0061763 Biological Process multivesicular body-lysosome fusion involved_in TAS
    GO:0070050 Biological Process neuron cellular homeostasis involved_in IMP
    GO:0031468 Biological Process nuclear membrane reassembly involved_in IMP
    GO:0006997 Biological Process nucleus organization involved_in IMP
    GO:0001778 Biological Process plasma membrane repair involved_in IDA
    GO:0015031 Biological Process protein transport involved_in IBA
    GO:0010824 Biological Process regulation of centrosome duplication involved_in IMP
    GO:1901673 Biological Process regulation of mitotic spindle assembly involved_in IMP
    GO:0099159 Biological Process regulation of modification of postsynaptic structure involved_in IEA
    GO:0099175 Biological Process regulation of postsynapse organization involved_in IEA
    GO:0043162 Biological Process ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway involved_in IDA
    GO:0051469 Biological Process vesicle fusion with vacuole involved_in NAS
    GO:0046761 Biological Process viral budding from plasma membrane involved_in IDA
    GO:0039702 Biological Process viral budding via host ESCRT complex involved_in IDA
    GO:0039702 Biological Process viral budding via host ESCRT complex involved_in IGI
    GO:0039702 Biological Process viral budding via host ESCRT complex involved_in IMP
    GO:0039702 Biological Process viral budding via host ESCRT complex involved_in TAS
    GO:0019076 Biological Process viral release from host cell involved_in IGI
    GO:0019076 Biological Process viral release from host cell involved_in IMP
    GO:0000815 Cellular Component ESCRT III complex part_of IBA
    GO:0000815 Cellular Component ESCRT III complex part_of IDA
    GO:0000815 Cellular Component ESCRT III complex part_of NAS
    GO:0000815 Cellular Component ESCRT III complex part_of TAS
    GO:1904930 Cellular Component amphisome membrane located_in IDA
    GO:0000421 Cellular Component autophagosome membrane located_in IDA
    GO:0005737 Cellular Component cytoplasm located_in IDA
    GO:0005829 Cellular Component cytosol located_in IDA
    GO:0005829 Cellular Component cytosol located_in TAS
    GO:0005768 Cellular Component endosome colocalizes_with IDA
    GO:0070062 Cellular Component extracellular exosome located_in HDA
    GO:0098978 Cellular Component glutamatergic synapse located_in IEA
    GO:0000776 Cellular Component kinetochore located_in IDA
    GO:0005828 Cellular Component kinetochore microtubule located_in IDA
    GO:0005770 Cellular Component late endosome colocalizes_with IDA
    GO:0005765 Cellular Component lysosomal membrane located_in IDA
    GO:0005764 Cellular Component lysosome colocalizes_with IDA
    GO:0030496 Cellular Component midbody located_in IDA
    GO:0005771 Cellular Component multivesicular body is_active_in IBA
    GO:0032585 Cellular Component multivesicular body membrane located_in IDA
    GO:0005643 Cellular Component nuclear pore part_of IDA
    GO:0005886 Cellular Component plasma membrane colocalizes_with IDA
    GO:0005886 Cellular Component plasma membrane located_in IDA
    GO:0014069 Cellular Component postsynaptic density located_in IEA
    Pathways
    Name DB ID
    HIV Life Cycle Reactome R-HSA-162587
    Budding and maturation of HIV virion Reactome R-HSA-162588
    Late Phase of HIV Life Cycle Reactome R-HSA-162599
    HIV Infection Reactome R-HSA-162906
    Macroautophagy Reactome R-HSA-1632852
    Cell Cycle Reactome R-HSA-1640170
    Disease Reactome R-HSA-1643685
    Membrane Trafficking Reactome R-HSA-199991
    Mitotic Metaphase and Anaphase Reactome R-HSA-2555396
    Nuclear Envelope (NE) Reassembly Reactome R-HSA-2995410
    Regulated Necrosis Reactome R-HSA-5218859
    Programmed Cell Death Reactome R-HSA-5357801
    Pyroptosis Reactome R-HSA-5620971
    Vesicle-mediated transport Reactome R-HSA-5653656
    Infectious disease Reactome R-HSA-5663205
    Mitotic Anaphase Reactome R-HSA-68882
    M Phase Reactome R-HSA-68886
    Cell Cycle, Mitotic Reactome R-HSA-69278
    Endosomal Sorting Complex Required For Transport (ESCRT) Reactome R-HSA-917729
    HCMV Infection Reactome R-HSA-9609646
    HCMV Late Events Reactome R-HSA-9610379
    Autophagy Reactome R-HSA-9612973
    Late endosomal microautophagy Reactome R-HSA-9615710
    Sealing of the nuclear envelope (NE) by ESCRT-III Reactome R-HSA-9668328
    SARS-CoV-1 Infection Reactome R-HSA-9678108
    Translation of Replicase and Assembly of the Replication Transcription Complex Reactome R-HSA-9679504
    SARS-CoV Infections Reactome R-HSA-9679506
    SARS-CoV-2 Infection Reactome R-HSA-9694516
    Translation of Replicase and Assembly of the Replication Transcription Complex Reactome R-HSA-9694676
    Early SARS-CoV-2 Infection Events Reactome R-HSA-9772572
    Viral Infection Pathways Reactome R-HSA-9824446
    Transcripts
    Accession Version MolecularType Name NCBI Comments
    NM_001410777 1 mRNA transcript variant 3 NC_000003 Reference
    NM_014043 4 mRNA transcript variant 1 NC_000003 Reference
    NM_001244644 2 mRNA transcript variant 2 NC_000003 Reference
    XM_011533576 3 mRNA transcript variant X1 NC_000003 Reference