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FGF21

fibroblast growth factor 21
General Information
Name fibroblast growth factor 21
Alias
  • fibroblast growth factor 21
Gene_family Fibroblast growth factor family
organism Homo sapiens
entrez_id 26291
location 19q13.33
transcript_count 1
exon_count 4
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez Theis gene encodes a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. This protein is a secreted endocrine factor that functions as a major metabolic regulator. The encoded protein stimulates the uptake of glucose in adipose tissue. [provided by RefSeq, Mar 2016]
    Stringdb Fibroblast growth factor 21; Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB; Belongs to the heparin-binding growth factors family
    nextProt Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB. Regulates systemic glucose homeostasis and insulin sensitivity.
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
FGF21 BioGRID NFE2L2 GeneID BioGRID Affinity Capture-Western
FGF21 BioGRID YPEL3 GeneID BioGRID Two-hybrid
FGF21 BioGRID SGTB GeneID BioGRID Two-hybrid
FGF21 BioGRID SGTA GeneID BioGRID Two-hybrid
FGF21 BioGRID TNS2 GeneID BioGRID Two-hybrid
FGF21 BioGRID MAPK7 GeneID BioGRID Two-hybrid
FGF21 BioGRID CDH7 GeneID BioGRID Two-hybrid
FGF21 BioGRID CDC25A GeneID BioGRID Two-hybrid
FGF21 BioGRID ELAVL1 GeneID BioGRID Affinity Capture-RNA
FGF21 BioGRID Nedd4 GeneID BioGRID Reconstituted Complex
FGF21 BioGRID NEDD4 GeneID BioGRID Reconstituted Complex
FGF21 Protein KLB GeneID HPRD
StringDB
A B experiments database textmining combined score hadb nhadb
FGF21 PTPN1 0 0 241 253 1 1
FGF21 ELN 0 0 69 279 1 1
FGF21 COX7A1 0 0 419 424 1 1
FGF21 APOA5 0 900 321 933 1 1
FGF21 OTX2 0 0 0 180 1 1
FGF21 STAT2 0 0 0 215 1 1
FGF21 GBE1 0 0 67 233 1 1
FGF21 XBP1 0 0 325 326 1 2
FGF21 ITGB3 0 0 0 155 1 1
FGF21 CRH 0 0 216 222 1 1
FGF21 MAP2K6 0 0 70 171 1 1
FGF21 KLF11 41 0 218 231 1 1
FGF21 ATG5 0 0 226 225 1 2
FGF21 WNT3A 0 0 53 341 1 2
FGF21 PREP 0 0 132 153 1 1
FGF21 EHMT1 0 0 136 156 1 1
FGF21 ZFP36L1 0 0 0 153 1 1
FGF21 COL6A6 0 0 0 266 1 1
FGF21 ESR1 0 0 204 286 1 2
FGF21 MAP3K5 0 0 151 152 1 1
FGF21 ITGAM 0 0 113 211 1 1
FGF21 T 0 0 0 286 1 1
FGF21 PDK4 0 0 505 510 1 1
FGF21 SMAD7 0 0 67 163 1 1
FGF21 ACTBL2 0 0 57 159 1 1
FGF21 TLE3 0 0 224 224 1 1
FGF21 DLK1 0 0 134 167 1 1
FGF21 SIRT1 0 0 653 653 1 2
FGF21 PLIN2 0 0 336 350 1 2
FGF21 PRL 0 0 139 191 1 1
FGF21 ACOX1 0 0 559 559 1 1
FGF21 KHK 0 0 292 292 1 1
FGF21 CTF1 0 0 81 165 1 1
FGF21 MMP13 0 0 90 215 1 2
FGF21 TBP 0 0 166 165 1 1
FGF21 VTN 0 0 0 232 1 1
FGF21 MT-CO1 0 0 170 169 1 1
FGF21 FN1 0 0 150 614 1 2
FGF21 MT-CYB 0 0 142 164 1 1
FGF21 GPX1 0 0 162 168 1 1
FGF21 ULK1 0 0 155 154 1 2
FGF21 CACNA1E 0 0 0 203 1 1
FGF21 SLC37A3 0 0 67 234 1 1
FGF21 NCAM1 0 0 0 183 1 1
FGF21 CAMK2A 0 0 181 232 1 2
FGF21 COQ4 0 0 101 192 1 1
FGF21 ADAM17 0 0 108 169 1 1
FGF21 FUT1 0 0 641 641 1 1
FGF21 SDC2 0 0 0 207 1 1
FGF21 HHAT 0 0 0 151 1 1
FGF21 TIMP2 0 0 47 193 1 1
FGF21 GLI1 0 0 0 191 1 2
FGF21 MGLL 0 0 166 165 1 1
FGF21 ADRB1 0 0 156 191 1 1
FGF21 TERT 0 0 0 155 1 2
FGF21 FLT3 0 600 0 674 1 2
FGF21 NAMPT 0 0 405 524 1 2
FGF21 PPARGC1B 0 0 289 289 1 1
FGF21 COL1A1 0 0 181 235 1 2
FGF21 CXCL2 0 0 118 210 1 1
FGF21 GFAP 0 0 45 294 1 2
FGF21 FGFR4 0 600 777 929 1 1
FGF21 CPT1C 0 0 421 425 1 1
FGF21 IL10 0 0 260 413 1 2
FGF21 SNAI1 0 0 0 250 1 1
FGF21 GDF15 0 0 561 573 1 1
FGF21 CNPY2 0 0 261 344 1 1
FGF21 NR1H4 0 0 607 616 1 1
FGF21 ACTG1 0 0 95 163 1 1
FGF21 SELE 0 0 90 190 1 1
FGF21 TGFBR2 0 0 81 177 1 1
FGF21 ATG7 0 0 295 295 1 2
FGF21 GDF5 0 0 93 172 1 1
FGF21 GABRA6 0 0 0 209 1 1
FGF21 AGRP 0 0 417 424 1 1
FGF21 ENG 0 0 54 261 1 2
FGF21 CCL3 0 0 135 194 1 1
FGF21 GOT2 0 0 228 229 1 1
FGF21 FGF12 0 0 324 366 1 1
FGF21 RET 0 0 57 276 1 1
FGF21 SOX10 0 0 0 302 1 1
FGF21 LMBR1 0 0 0 157 1 1
FGF21 SMAD5 0 0 0 169 1 1
FGF21 NTF4 0 0 54 190 1 1
FGF21 IGF2 0 0 149 426 1 1
FGF21 AXIN1 0 0 53 152 1 1
FGF21 NGFR 0 600 0 640 1 1
FGF21 SREBF1 0 0 631 640 1 1
FGF21 SLC27A2 0 0 261 277 1 1
FGF21 UCP1 0 0 801 801 1 2
FGF21 TNFRSF9 0 0 267 267 1 1
FGF21 MAPK14 0 0 75 169 1 2
FGF21 NFKBIA 0 0 134 188 1 2
FGF21 KIT 0 600 67 755 1 2
FGF21 LEP 0 0 725 731 1 1
FGF21 BMP4 0 0 171 508 1 1
FGF21 TCF4 0 0 89 154 1 1
FGF21 RARB 0 0 167 239 1 1
FGF21 WT1 0 0 90 175 1 1
FGF21 PRKAA2 0 0 57 225 1 2
FGF21 FFAR4 0 0 391 390 1 1
FGF21 FMO3 0 0 124 158 1 1
FGF21 MMP11 0 0 0 369 1 1
FGF21 GAPDHS 0 0 0 210 1 1
FGF21 MYOD1 0 0 212 266 1 1
FGF21 PTEN 0 0 170 311 1 2
FGF21 VEGFA 0 0 294 486 1 2
FGF21 NFIA 0 0 0 190 1 1
FGF21 NLRP3 0 0 181 181 1 2
FGF21 ATG101 0 0 45 378 1 2
FGF21 MMP14 0 0 57 157 1 1
FGF21 IL33 0 0 164 177 1 2
FGF21 CXCL1 0 0 123 215 1 2
FGF21 PLIN3 0 0 163 163 1 1
FGF21 TRIB3 0 0 260 276 1 2
FGF21 HCRT 0 0 260 260 1 1
FGF21 PTGS2 0 0 187 309 1 2
FGF21 EEF1A1 0 0 63 162 1 1
FGF21 CCL11 0 0 155 238 1 1
FGF21 FGF19 0 0 803 208 1 1
FGF21 NQO1 0 0 262 262 1 2
FGF21 CASP3 0 0 241 359 1 2
FGF21 ERBB3 0 600 57 634 1 1
FGF21 AFP 0 0 116 289 1 2
FGF21 NFIB 0 0 0 175 1 1
FGF21 LIPC 0 0 155 154 1 1
FGF21 FIGF 0 0 52 306 1 1
FGF21 REN 0 0 213 296 1 1
FGF21 IL13 0 0 167 295 1 2
FGF21 NOTCH2 0 0 0 201 1 1
FGF21 ACE 0 0 180 247 1 1
FGF21 ANG 0 0 0 220 1 2
FGF21 FGF22 0 0 469 188 1 1
FGF21 IHH 0 0 74 379 1 1
FGF21 FGFRL1 0 0 102 303 1 1
FGF21 CXCL5 0 0 57 152 1 1
FGF21 ENSG00000268643 0 0 0 157 1 1
FGF21 GDF11 0 0 172 178 1 1
FGF21 VEGFC 0 0 52 308 1 1
FGF21 COQ5 0 0 122 272 1 1
FGF21 BHLHA15 0 0 113 266 1 1
FGF21 FGF8 0 0 325 325 1 1
FGF21 ITGAX 0 0 126 180 1 1
FGF21 TTR 0 0 90 159 1 1
FGF21 GSK3B 0 0 123 372 1 2
FGF21 GK 0 0 218 235 1 1
FGF21 SOCS2 0 0 314 339 1 1
FGF21 SST 0 0 181 220 1 1
FGF21 FABP4 0 0 529 529 1 1
FGF21 CREG1 0 0 142 164 1 1
FGF21 ANGPTL3 0 0 243 259 1 1
FGF21 KLF2 0 0 53 168 1 1
FGF21 PNPLA3 0 0 400 404 1 1
FGF21 AGPAT2 0 0 186 203 1 1
FGF21 INSRR 0 600 0 624 1 1
FGF21 NTF3 0 0 90 387 1 1
FGF21 WNT2 0 0 53 576 1 1
FGF21 CEBPB 0 0 341 341 1 2
FGF21 FGF9 0 0 396 176 1 1
FGF21 ACOT1 0 0 392 399 1 1
FGF21 GHR 0 0 297 302 1 1
FGF21 TBX15 0 0 166 173 1 1
FGF21 ABCB4 0 0 122 151 1 1
FGF21 CSF1 0 0 107 201 1 1
FGF21 WNT3 0 0 0 199 1 1
FGF21 TRPV5 0 0 134 188 1 1
FGF21 FGF11 0 0 505 537 1 1
FGF21 AHSG 0 0 559 569 1 1
FGF21 BDH1 0 0 368 381 1 1
FGF21 SOCS3 0 0 242 248 1 1
FGF21 FGL1 0 0 170 190 1 1
FGF21 GNMT 0 0 216 233 1 1
FGF21 GHSR 0 0 181 181 1 1
FGF21 THRB 0 0 193 208 1 1
FGF21 FOS 0 0 261 339 1 2
FGF21 PTPN11 0 0 88 234 1 1
FGF21 PDX1 0 0 97 153 1 1
FGF21 MSTN 0 0 469 472 1 1
FGF21 G6PC2 0 0 0 166 1 1
FGF21 MMP24 0 0 0 300 1 1
FGF21 RXRA 0 0 137 196 1 1
FGF21 STAT5A 0 0 290 308 1 1
FGF21 PON1 0 0 142 173 1 1
FGF21 ANGPTL4 0 0 503 513 1 1
FGF21 HSPA5 0 0 241 257 1 2
FGF21 FGF20 0 0 361 173 1 1
FGF21 SLC34A3 0 0 189 195 1 1
FGF21 GPBAR1 0 0 464 463 1 1
FGF21 PTH 0 0 277 420 1 1
FGF21 DRAP1 0 0 0 150 1 1
FGF21 HOXC8 0 0 195 195 1 1
FGF21 SOD2 0 0 277 277 1 2
FGF21 FOXO1 0 0 404 414 1 2
FGF21 KRAS 0 0 70 196 1 2
FGF21 EPAS1 0 0 62 158 1 2
FGF21 COX4I2 0 0 180 179 1 1
FGF21 LEPROTL1 0 0 266 279 1 1
FGF21 IL2 0 0 75 275 1 1
FGF21 THBS1 0 0 75 284 1 1
FGF21 BECN1 0 0 209 209 1 2
FGF21 MET 0 600 67 695 1 2
FGF21 ANGPT4 0 0 97 187 1 1
FGF21 SLC5A2 0 0 286 286 1 1
FGF21 ACADL 0 0 294 294 1 1
FGF21 FLT4 0 600 48 736 1 1
FGF21 FGF23 0 0 739 243 1 1
FGF21 DUSP1 0 0 123 176 1 1
FGF21 ACADVL 0 0 290 290 1 1
FGF21 MED1 0 0 150 168 1 1
FGF21 LPIN1 0 0 325 325 1 2
FGF21 PGF 0 0 64 441 1 1
FGF21 SCN8A 0 0 0 161 1 1
FGF21 SPRY4 0 0 99 238 1 1
FGF21 NOX4 0 0 142 201 1 2
FGF21 FABP2 0 0 134 292 1 1
FGF21 SLN 0 0 154 153 1 1
FGF21 PSMD5 0 0 139 161 1 1
FGF21 RUNX2 0 0 134 429 1 2
FGF21 ASNS 0 0 245 244 1 1
FGF21 NTRK2 0 600 70 651 1 1
FGF21 ABCG8 0 0 229 246 1 1
FGF21 FGFR1 0 800 988 998 1 1
FGF21 ACACB 0 0 310 329 1 1
FGF21 SLC2A5 0 0 194 194 1 1
FGF21 KLF4 0 0 57 273 1 2
FGF21 ACE2 0 0 125 179 1 2
FGF21 SCN5A 0 0 0 161 1 1
FGF21 ATF6 0 0 290 292 1 2
FGF21 CYP8B1 0 0 340 367 1 1
FGF21 PTHLH 0 0 113 227 1 1
FGF21 PRDM16 0 0 653 665 1 1
FGF21 LYPLAL1 0 0 62 207 1 1
FGF21 SCN9A 0 0 0 161 1 1
FGF21 VCAM1 0 0 150 377 1 1
FGF21 ATF4 0 0 529 543 1 2
FGF21 CD4 0 0 123 258 1 2
FGF21 PPARG 0 0 683 690 1 2
FGF21 TGFB2 0 0 113 179 1 1
FGF21 BHMT 0 0 194 200 1 1
FGF21 APLN 0 0 390 390 1 1
FGF21 AKT1 0 0 509 597 1 2
FGF21 CPT1A 0 0 595 595 1 1
FGF21 UGT1A1 0 0 146 157 1 1
FGF21 CLPP 0 0 204 214 1 1
FGF21 CSF2 0 0 84 357 1 1
FGF21 NOTCH2NL 0 0 0 201 1 1
FGF21 ERBB2 0 600 67 672 1 2
FGF21 ENSG00000274276 0 0 183 195 1 1
FGF21 NGF 0 0 134 588 1 2
FGF21 CD34 0 0 91 487 1 2
FGF21 GYS2 0 0 182 200 1 1
FGF21 VEGFB 0 0 92 235 1 1
FGF21 TH 0 0 216 265 1 2
FGF21 SHBG 0 0 292 292 1 1
FGF21 YES1 0 0 0 190 1 1
FGF21 GPRC6A 0 0 183 183 1 1
FGF21 YME1L1 0 0 155 154 1 1
FGF21 MGAM 0 0 180 179 1 1
FGF21 NR5A2 0 0 126 184 1 1
FGF21 NR1I2 0 0 269 293 1 1
FGF21 VLDLR 0 0 301 314 1 1
FGF21 ASPG 0 0 180 240 1 1
FGF21 C1QTNF1 0 0 142 161 1 1
FGF21 ALAS1 0 0 193 193 1 1
FGF21 FGF3 0 0 359 173 1 1
FGF21 CXCL10 0 0 137 270 1 2
FGF21 LPA 0 0 95 219 1 1
FGF21 BSCL2 0 0 134 182 1 1
FGF21 KRT18 0 0 359 373 1 1
FGF21 EIF4EBP1 0 0 242 241 1 2
FGF21 APOA2 0 0 155 176 1 1
FGF21 CERS4 0 0 71 169 1 1
FGF21 IL11 0 0 53 155 1 1
FGF21 SEPP1 0 0 467 467 1 1
FGF21 GPT 0 0 517 517 1 1
FGF21 BMP8B 0 0 542 545 1 1
FGF21 LRRC66 0 0 134 168 1 1
FGF21 ID2 0 0 0 424 1 1
FGF21 SIRT4 0 0 340 340 1 1
FGF21 GJA1 0 0 0 200 1 1
FGF21 CCK 0 0 291 304 1 1
FGF21 GSK3A 0 0 0 157 1 1
FGF21 PINK1 0 0 150 173 1 2
FGF21 CHRD 0 0 0 258 1 1
FGF21 HNF4A 0 0 317 363 1 1
FGF21 EIF2AK3 0 0 321 321 1 2
FGF21 STAT6 0 0 77 244 1 1
FGF21 ACLY 0 0 267 267 1 1
FGF21 LGALS3 0 0 137 190 1 2
FGF21 MIF 0 0 61 164 1 2
FGF21 FLT1 0 600 62 777 1 1
FGF21 FGFBP2 0 0 0 340 1 1
FGF21 ECH1 0 0 194 194 1 1
FGF21 COASY 0 0 202 202 1 1
FGF21 COQ6 0 0 122 160 1 1
FGF21 SIM1 0 0 142 160 1 1
FGF21 IZUMO1 0 0 150 169 1 1
FGF21 HP 0 0 145 195 1 1
FGF21 PDGFRL 0 0 0 198 1 1
FGF21 ACTL6A 0 0 0 252 1 1
FGF21 SCD 0 0 556 556 1 1
FGF21 SRC 0 0 134 369 1 2
FGF21 DKK1 0 0 45 263 1 1
FGF21 F2 0 0 46 320 1 1
FGF21 CDC42 0 0 55 176 1 2
FGF21 TNFSF11 0 0 193 273 1 2
FGF21 BGLAP 0 0 261 418 1 1
FGF21 DGAT2 0 0 403 416 1 1
FGF21 IGFALS 0 0 184 202 1 1
FGF21 CREB5 0 0 0 432 1 1
FGF21 CRY1 0 0 167 167 1 1
FGF21 IL36B 0 0 0 276 1 1
FGF21 FOXO3 0 0 260 293 1 2
FGF21 SPRED1 0 0 57 156 1 1
FGF21 SLC2A4 0 0 526 536 1 1
FGF21 OXT 0 0 138 177 1 1
FGF21 PCSK9 0 0 212 229 1 1
FGF21 ETFDH 0 0 119 176 1 1
FGF21 TM6SF2 0 0 324 338 1 1
FGF21 CNPY1 0 0 153 240 1 1
FGF21 APOE 0 0 325 354 1 2
FGF21 ADCK3 0 0 181 199 1 1
FGF21 MMP10 0 0 60 313 1 1
FGF21 DIO2 0 0 595 595 1 1
FGF21 CDH4 0 0 0 189 1 1
FGF21 TGFB1 0 0 142 439 1 2
FGF21 KRT19 0 0 83 174 1 1
FGF21 TSC2 0 0 143 196 1 2
FGF21 INSL4 0 0 0 234 1 1
FGF21 MC4R 0 0 260 260 1 1
FGF21 STAT5B 0 0 320 337 1 1
FGF21 YY1 0 0 155 168 1 1
FGF21 KDR 0 600 74 803 1 2
FGF21 RARRES2 0 0 464 475 1 1
FGF21 MMP12 0 0 49 192 1 1
FGF21 EIF2S1 0 0 327 327 1 2
FGF21 APOC2 0 900 261 924 1 1
FGF21 HMOX1 0 0 322 321 1 2
FGF21 CACNA1A 0 0 0 203 1 1
FGF21 NRG1 0 0 59 169 1 2
FGF21 ADIPOR2 0 0 324 323 1 1
FGF21 PRDM2 0 0 163 164 1 1
FGF21 PECAM1 0 0 120 573 1 1
FGF21 CAT 0 0 261 274 1 2
FGF21 GIP 0 0 288 288 1 1
FGF21 WNT10B 0 0 113 201 1 1
FGF21 DUSP6 0 0 134 255 1 1
FGF21 COL6A3 0 0 0 436 1 1
FGF21 SLC27A4 0 0 134 151 1 1
FGF21 TBX1 0 0 294 294 1 1
FGF21 RUNX1 0 0 0 187 1 2
FGF21 TXN 0 0 134 176 1 1
FGF21 ABCG5 0 0 261 277 1 1
FGF21 POU5F1 0 0 0 290 1 2
FGF21 FADS2 0 0 232 231 1 1
FGF21 FADS1 0 0 181 181 1 1
FGF21 FSTL1 0 0 358 358 1 1
FGF21 HGF 0 0 142 679 1 2
FGF21 ENSG00000264813 0 0 181 229 1 1
FGF21 HPRT1 0 0 155 173 1 1
FGF21 BCAT2 0 0 144 167 1 1
FGF21 FOXA2 0 0 166 257 1 1
FGF21 NR1D1 0 0 360 360 1 2
FGF21 SPRY1 0 0 66 435 1 1
FGF21 FGF16 0 0 464 194 1 1
FGF21 GPAM 0 0 248 248 1 1
FGF21 LDLR 0 0 269 283 1 2
FGF21 DFFA 0 0 171 350 1 1
FGF21 PPP1R3G 0 0 171 171 1 1
FGF21 SLC27A1 0 0 336 353 1 1
FGF21 SREBF2 0 0 391 394 1 1
FGF21 CCND1 0 0 136 322 1 2
FGF21 ENSG00000273171 0 0 0 232 1 1
FGF21 CACNA1B 0 0 0 203 1 1
FGF21 PRKAA1 0 0 77 160 1 2
FGF21 INS-IGF2 0 0 0 605 1 1
FGF21 CD36 0 0 310 315 1 2
FGF21 PC 0 0 216 223 1 1
FGF21 NOS3 0 0 253 273 1 2
FGF21 OSGIN2 0 0 0 248 1 1
FGF21 TRH 0 0 150 188 1 1
FGF21 FOXC2 0 0 234 234 1 1
FGF21 FAM132B 0 0 261 261 1 1
FGF21 FGF5 0 0 310 173 1 1
FGF21 WNT8B 0 0 0 191 1 1
FGF21 CYP24A1 0 0 170 202 1 1
FGF21 HMGCR 0 0 324 328 1 1
FGF21 NTRK1 0 600 124 657 1 1
FGF21 EGR2 0 0 61 156 1 1
FGF21 LOX 0 0 194 259 1 2
FGF21 IRS1 0 0 452 452 1 2
FGF21 C10orf2 0 0 281 282 1 1
FGF21 HSPA9 0 0 113 170 1 1
FGF21 ADRB2 0 0 145 172 1 1
FGF21 RPS6KB1 0 0 264 274 1 2
FGF21 LECT2 0 0 424 437 1 1
FGF21 SERPINE1 0 0 284 344 1 1
FGF21 AHR 0 0 240 240 1 2
FGF21 CDK1 0 0 52 177 1 2
FGF21 NCOR1 0 0 244 243 1 1
FGF21 MMP27 0 0 0 369 1 1
FGF21 APOB 0 0 455 466 1 2
FGF21 CSF1R 0 600 51 677 1 1
FGF21 IGF1 0 0 561 794 1 2
FGF21 MAPK1 0 0 384 421 1 2
FGF21 FABP1 0 0 310 325 1 1
FGF21 ARNTL 0 0 323 323 1 1
FGF21 SCN4A 0 0 0 161 1 1
FGF21 GADD45A 0 0 167 167 1 1
FGF21 ATF3 0 0 271 292 1 2
FGF21 CDH5 0 0 74 171 1 1
FGF21 RETN 0 0 520 523 1 1
FGF21 THRSP 0 0 261 261 1 1
FGF21 FGF2 0 0 394 309 1 2
FGF21 SUPT5H 0 0 270 270 1 1
FGF21 TXNIP 0 0 234 239 1 2
FGF21 MMP8 0 0 0 370 1 1
FGF21 BCL2A1 0 0 181 181 1 1
FGF21 SPRY2 0 0 58 375 1 1
FGF21 AGT 0 0 181 281 1 1
FGF21 IL5 0 0 88 227 1 1
FGF21 VWF 0 0 74 389 1 1
FGF21 GCG 0 0 721 721 1 1
FGF21 PTCH1 0 0 0 178 1 1
FGF21 C1QTNF9 0 0 155 154 1 1
FGF21 APOC3 0 0 340 361 1 1
FGF21 SLC13A1 0 0 94 150 1 1
FGF21 CBSL 0 0 183 195 1 1
FGF21 PPP1R15A 0 0 185 185 1 2
FGF21 RPLP0 0 0 95 186 1 1
FGF21 MLYCD 0 0 167 167 1 1
FGF21 PDGFC 0 0 112 249 1 1
FGF21 ACADM 0 0 414 414 1 1
FGF21 GH1 0 0 163 169 1 1
FGF21 MMP7 0 0 0 369 1 1
FGF21 NRIP1 0 0 324 323 1 1
FGF21 BDNF 0 0 348 548 1 2
FGF21 MMP25 0 0 0 369 1 1
FGF21 CD44 0 0 91 407 1 2
FGF21 NT5E 0 0 0 323 1 1
FGF21 IL7 0 0 143 228 1 1
FGF21 MMP3 0 0 135 476 1 1
FGF21 MLX 0 0 189 189 1 1
FGF21 ZFP36L2 0 0 0 153 1 1
FGF21 IL1RN 0 0 122 176 1 1
FGF21 UCP3 0 0 466 469 1 1
FGF21 ABHD5 0 0 268 268 1 1
FGF21 VDR 0 0 217 228 1 2
FGF21 MSX1 0 0 0 161 1 1
FGF21 TNF 0 0 427 532 1 2
FGF21 C19orf80 0 0 414 426 1 1
FGF21 DICER1 0 0 150 188 1 1
FGF21 GCGR 0 0 519 542 1 1
FGF21 HSPA4 0 0 107 190 1 1
FGF21 LIF 0 0 217 492 1 2
FGF21 GATA4 0 0 48 274 1 2
FGF21 CFD 0 0 323 323 1 1
FGF21 PPY 0 0 150 220 1 1
FGF21 PPARA 0 0 809 815 1 2
FGF21 CETP 0 0 134 166 1 1
FGF21 LPL 0 0 470 481 1 1
FGF21 TEK 0 600 61 755 1 1
FGF21 HMGCL 0 0 301 309 1 1
FGF21 NES 0 0 61 441 1 2
FGF21 RPTOR 0 0 205 205 1 2
FGF21 CYP2E1 0 0 181 198 1 2
FGF21 TIE1 0 0 0 271 1 1
FGF21 LHX8 0 0 181 279 1 1
FGF21 SLC27A5 0 0 234 252 1 1
FGF21 CYCS 0 0 171 183 1 2
FGF21 NRP1 0 0 0 188 1 1
FGF21 PLGLB1 0 0 0 173 1 1
FGF21 MAPK9 0 0 155 155 1 2
FGF21 MIER1 0 0 0 290 1 1
FGF21 NANOG 0 0 0 373 1 2
FGF21 POMC 0 0 366 366 1 1
FGF21 SQLE 0 0 108 163 1 1
FGF21 FCGRT 0 0 96 173 1 1
FGF21 FASN 0 0 519 531 1 2
FGF21 PLAU 0 0 60 156 1 1
FGF21 IGFBP1 0 0 401 414 1 1
FGF21 IL17A 0 0 147 301 1 2
FGF21 HNF1A 0 0 124 292 1 1
FGF21 EGF 0 0 172 696 1 2
FGF21 COQ2 0 0 108 199 1 1
FGF21 CYP27A1 0 0 194 217 1 1
FGF21 BMP2 0 0 112 512 1 1
FGF21 MAPK8 0 0 202 219 1 2
FGF21 ADIPOQ 0 0 754 778 1 2
FGF21 BHLHE40 0 0 89 151 1 1
FGF21 SLC51A 0 0 124 180 1 1
FGF21 ENO2 0 0 0 209 1 1
FGF21 BRAF 0 0 0 252 1 2
FGF21 FGF18 0 0 395 432 1 1
FGF21 PHOSPHO1 0 0 154 153 1 1
FGF21 BCKDK 0 0 151 150 1 1
FGF21 SESN2 0 0 202 202 1 2
FGF21 NFIC 0 0 0 175 1 1
FGF21 HIST2H3PS2 0 0 139 192 1 1
FGF21 SURF1 0 0 160 159 1 1
FGF21 VR1 0 0 107 162 1 1
FGF21 IL1F10 0 0 0 298 1 1
FGF21 MMP16 0 0 0 302 1 1
FGF21 PDGFA 0 0 54 226 1 1
FGF21 CISH 0 0 141 175 1 1
FGF21 GPD1L 0 0 0 215 1 1
FGF21 CPT1B 0 0 467 478 1 1
FGF21 NR3C1 0 0 241 304 1 1
FGF21 CTGF 0 0 217 395 1 1
FGF21 NFIL3 0 0 243 242 1 1
FGF21 LGALS4 0 0 143 196 1 1
FGF21 DPP4 0 0 393 401 1 1
FGF21 POLG 0 0 123 202 1 1
FGF21 CYP3A4 0 0 170 188 1 1
FGF21 WNT1 0 0 48 212 1 2
FGF21 PIK3AP1 0 0 0 226 1 1
FGF21 PAX6 0 0 0 272 1 1
FGF21 IAPP 0 0 321 321 1 2
FGF21 ABCA1 0 0 309 309 1 2
FGF21 ACAA1 0 0 92 152 1 1
FGF21 FETUB 0 0 325 357 1 1
FGF21 IL1A 0 0 135 340 1 1
FGF21 CCL4 0 0 107 171 1 1
FGF21 ALDH3A2 0 0 156 179 1 1
FGF21 INSL6 0 0 161 161 1 1
FGF21 CTH 0 0 210 227 1 1
FGF21 HMGCS2 0 0 526 537 1 1
FGF21 SIRT6 0 0 369 369 1 2
FGF21 CP 0 0 73 232 1 1
FGF21 CERS2 0 0 82 179 1 1
FGF21 BMP7 0 0 452 506 1 1
FGF21 FGF17 0 0 382 426 1 1
FGF21 CDH1 0 0 74 392 1 2
FGF21 NRG4 0 0 558 561 1 1
FGF21 PDGFRA 0 600 97 707 1 1
FGF21 OSGIN1 0 0 57 391 1 1
FGF21 FNDC5 0 0 795 795 1 1
FGF21 PLG 0 0 95 219 1 1
FGF21 MLXIPL 0 0 612 612 1 1
FGF21 PKLR 0 0 268 293 1 1
FGF21 IL4 0 0 183 310 1 1
FGF21 SCARB1 0 0 171 171 1 1
FGF21 GIPR 0 0 194 239 1 1
FGF21 CDK5 0 0 157 156 1 2
FGF21 ADIPOR1 0 0 340 340 1 1
FGF21 EP300 0 0 134 153 1 2
FGF21 PDGFRB 0 600 81 745 1 2
FGF21 HNF1B 0 0 0 197 1 1
FGF21 ERO1L 0 0 183 183 1 1
FGF21 CNTF 0 0 64 435 1 1
FGF21 ONECUT1 0 0 94 154 1 1
FGF21 SPARC 0 0 193 302 1 2
FGF21 SMAD3 0 0 181 316 1 2
FGF21 CRY2 0 0 181 181 1 1
FGF21 CD68 0 0 207 237 1 2
FGF21 ENHO 0 0 391 390 1 1
FGF21 GADD45GIP1 0 0 247 265 1 1
FGF21 ALB 0 0 420 645 1 2
FGF21 CCL2 0 0 358 409 1 2
FGF21 SLC6A19 0 0 186 186 1 1
FGF21 SNAI2 0 0 0 208 1 1
FGF21 CREB3L3 0 900 557 955 1 1
FGF21 LEPR 0 0 423 427 1 1
FGF21 DUSP7 0 0 0 175 1 1
FGF21 HSPG2 0 0 0 222 1 1
FGF21 ADRB3 0 0 698 716 1 1
FGF21 ITGB1 0 0 66 321 1 1
FGF21 FAP 0 0 218 224 1 2
FGF21 ITLN1 0 0 459 459 1 1
FGF21 HSP90AA1 0 0 123 195 1 2
FGF21 PNPLA2 0 0 563 572 1 2
FGF21 PAX8 0 0 0 152 1 1
FGF21 IL3 0 0 60 160 1 1
FGF21 HADHA 0 0 211 241 1 1
FGF21 TFEB 0 0 282 282 1 2
FGF21 IL21 0 0 0 396 1 1
FGF21 SP7 0 0 91 242 1 1
FGF21 COQ7 0 0 127 198 1 1
FGF21 CEBPA 0 0 390 403 1 1
FGF21 DEC1 0 0 107 189 1 1
FGF21 SOX2 0 0 0 390 1 2
FGF21 COX4I1 0 0 261 261 1 1
FGF21 CRP 0 0 456 470 1 2
FGF21 ATF2 0 0 155 161 1 1
FGF21 SERPINA12 0 0 416 428 1 1
FGF21 FOXG1 0 0 123 273 1 1
FGF21 ACTB 0 0 391 453 1 2
FGF21 INS 0 0 759 824 1 2
FGF21 GLP1R 0 0 420 432 1 1
FGF21 FGF1 0 0 556 256 1 1
FGF21 SLC5A11 0 0 91 183 1 1
FGF21 ENO3 0 0 48 167 1 1
FGF21 THY1 0 0 46 305 1 1
FGF21 ANGPT1 0 0 90 432 1 1
FGF21 ABCG1 0 0 208 208 1 2
FGF21 SIRT3 0 0 409 408 1 2
FGF21 PROM1 0 0 0 420 1 2
FGF21 MAPK3 0 0 488 540 1 2
FGF21 KLF15 0 0 181 211 1 1
FGF21 PAX5 0 0 0 151 1 1
FGF21 KEAP1 0 0 249 248 1 2
FGF21 MMP9 0 0 174 396 1 2
FGF21 B2M 0 0 181 198 1 1
FGF21 BNIP3 0 0 154 153 1 2
FGF21 SQSTM1 0 0 171 171 1 2
FGF21 GLI3 0 0 0 156 1 1
FGF21 PCK2 0 0 459 474 1 1
FGF21 SPP1 0 0 162 376 1 2
FGF21 PLIN5 0 0 324 340 1 1
FGF21 RHOA 0 0 66 220 1 2
FGF21 AR 0 0 90 189 1 2
FGF21 SOX8 0 0 48 182 1 1
FGF21 GDF10 0 0 0 254 1 1
FGF21 EPCAM 0 0 67 161 1 2
FGF21 BANK1 0 0 0 168 1 1
FGF21 GNRH1 0 0 143 196 1 1
FGF21 CRTC2 0 0 325 326 1 1
FGF21 ETV4 0 0 54 267 1 1
FGF21 INSR 0 600 244 703 1 1
FGF21 PLA2G1B 0 0 63 165 1 1
FGF21 FABP5 0 0 180 179 1 1
FGF21 CARTPT 0 0 157 177 1 1
FGF21 MTTP 0 0 293 309 1 1
FGF21 IL36A 0 0 0 298 1 1
FGF21 TIMP1 0 0 211 345 1 1
FGF21 FGF4 0 0 342 155 1 1
FGF21 PYY 0 0 414 414 1 1
FGF21 IGFBP2 0 0 211 211 1 1
FGF21 SLC10A2 0 0 166 185 1 1
FGF21 ESR2 0 0 72 152 1 1
FGF21 EHHADH 0 0 378 415 1 1
FGF21 PTPRC 0 0 93 416 1 1
FGF21 SOST 0 0 150 237 1 1
FGF21 ZEB1 0 0 0 200 1 2
FGF21 SIRT7 0 0 364 364 1 2
FGF21 ELOVL3 0 0 556 565 1 1
FGF21 GALNT3 0 0 357 357 1 1
FGF21 SOX9 0 0 106 349 1 1
FGF21 LCTL 0 0 243 284 1 1
FGF21 FOXD3 0 0 0 154 1 1
FGF21 ICAM1 0 0 181 329 1 2
FGF21 GHRH 0 0 210 219 1 1
FGF21 NDUFA3 0 0 45 192 1 1
FGF21 INSIG2 0 0 299 299 1 1
FGF21 JAG1 0 0 0 196 1 1
FGF21 FST 0 0 314 380 1 1
FGF21 RMND1 0 0 156 155 1 1
FGF21 GRB2 0 0 107 223 1 1
FGF21 GRN 0 0 155 157 1 1
FGF21 FYN 0 0 90 152 1 1
FGF21 CITED1 0 0 270 270 1 1
FGF21 SHH 0 0 49 538 1 2
FGF21 ANGPTL6 0 0 507 517 1 1
FGF21 FGF6 0 0 422 161 1 1
FGF21 IL37 0 0 0 298 1 1
FGF21 IL36RN 0 0 0 298 1 1
FGF21 SOD1 0 0 180 179 1 2
FGF21 TBC1D4 0 0 150 264 1 1
FGF21 ELOVL6 0 0 369 374 1 1
FGF21 IRS2 0 0 362 362 1 1
FGF21 PEMT 0 0 142 174 1 1
FGF21 SMAD1 0 0 66 190 1 2
FGF21 IGFBP3 0 0 162 192 1 2
FGF21 UGT1A8 0 0 147 174 1 1
FGF21 SLC27A6 0 0 241 257 1 1
FGF21 MMP2 0 0 116 316 1 2
FGF21 AGRN 0 0 45 169 1 1
FGF21 RBP4 0 0 517 527 1 1
FGF21 CNPY3 0 0 103 347 1 1
FGF21 ANGPT2 0 0 95 301 1 1
FGF21 FGFR1OP2 0 0 96 152 1 1
FGF21 SLC36A2 0 0 180 179 1 1
FGF21 TFAM 0 0 359 363 1 2
FGF21 COX15 0 0 134 152 1 1
FGF21 NCOA2 0 0 113 271 1 1
FGF21 DNTT 0 0 76 166 1 1
FGF21 CYP7A1 0 0 518 537 1 1
FGF21 PER2 0 0 211 211 1 1
FGF21 OTOP1 0 0 161 161 1 1
FGF21 CAV1 0 0 123 183 1 2
FGF21 ERBB4 0 600 46 630 1 1
FGF21 ZFP36 0 0 54 164 1 1
FGF21 SRF 0 0 112 180 1 1
FGF21 HSPA1A 0 0 123 161 1 1
FGF21 NRF1 0 0 213 213 1 2
FGF21 MTHFD2 0 0 210 227 1 1
FGF21 SI 0 0 170 169 1 1
FGF21 KL 0 0 844 870 1 2
FGF21 GLG1 0 0 0 210 1 1
FGF21 NPPB 0 0 235 235 1 1
FGF21 CDH17 0 0 0 163 1 1
FGF21 MPZL2 0 0 206 206 1 1
FGF21 FABP3 0 0 296 296 1 1
FGF21 BCS1L 0 0 183 188 1 1
FGF21 JUN 0 0 284 359 1 2
FGF21 SCN3A 0 0 0 161 1 1
FGF21 METRNL 0 0 423 422 1 1
FGF21 GAPDH 0 0 370 467 1 2
FGF21 ELOVL5 0 0 257 256 1 1
FGF21 CYP1A1 0 0 156 181 1 2
FGF21 FGFR2 0 600 451 890 1 1
FGF21 ENO1 0 0 47 307 1 1
FGF21 EMR1 0 0 88 152 1 1
FGF21 SMAD2 0 0 162 390 1 2
FGF21 TLR4 0 0 232 280 1 2
FGF21 PLGLB2 0 0 0 173 1 1
FGF21 MAP2K7 0 0 127 181 1 1
FGF21 CX3CL1 0 0 142 195 1 1
FGF21 APOA1 0 0 363 378 1 1
FGF21 HAMP 0 0 156 174 1 1
FGF21 SLC25A20 0 0 235 235 1 1
FGF21 KISS1 0 0 254 254 1 1
FGF21 STAT4 0 0 0 248 1 1
FGF21 ZIC1 0 0 294 313 1 1
FGF21 SH2D1B 0 0 48 193 1 1
FGF21 MMP20 0 0 0 363 1 1
FGF21 ME1 0 0 136 155 1 1
FGF21 ALDH1A2 0 0 0 189 1 1
FGF21 KITLG 0 0 635 635 1 1
FGF21 ACSS2 0 0 167 167 1 1
FGF21 RORA 0 0 161 180 1 1
FGF21 BCL2L1 0 0 90 166 1 2
FGF21 SLC5A4 0 0 267 267 1 1
FGF21 FBXO32 0 0 177 183 1 2
FGF21 SULT2A1 0 0 124 150 1 1
FGF21 CYP4X1 0 0 63 156 1 1
FGF21 FTO 0 0 261 261 1 2
FGF21 NPPA 0 0 165 186 1 1
FGF21 WNT8A 0 0 0 263 1 1
FGF21 ANXA5 0 0 66 268 1 2
FGF21 CS 0 0 217 217 1 1
FGF21 METRN 0 0 500 499 1 1
FGF21 GPD1 0 0 103 348 1 1
FGF21 EPO 0 0 122 360 1 2
FGF21 ATF5 0 0 373 386 1 1
FGF21 PHEX 0 0 211 301 1 1
FGF21 SCAP 0 0 134 158 1 1
FGF21 SIRT2 0 0 335 335 1 2
FGF21 BCKDHA 0 0 134 150 1 1
FGF21 GCKR 0 0 170 219 1 1
FGF21 CYP17A1 0 0 122 164 1 1
FGF21 HAVCR1 0 0 155 154 1 1
FGF21 LONP1 0 0 235 248 1 1
FGF21 ESRRA 0 0 242 241 1 1
FGF21 GRB10 0 0 129 157 1 1
FGF21 SDHB 0 0 167 167 1 1
FGF21 TMEM26 0 0 469 478 1 1
FGF21 TENC1 170 0 0 169 1 1
FGF21 G0S2 0 0 195 222 1 1
FGF21 CIDEC 0 900 455 944 1 1
FGF21 ELOVL2 0 0 184 189 1 1
FGF21 CREB1 0 0 329 376 1 2
FGF21 CCL5 0 0 107 309 1 2
FGF21 PCTP 0 0 150 173 1 1
FGF21 MBOAT7 0 0 155 154 1 1
FGF21 FGF14 0 0 392 200 1 1
FGF21 HSD11B1 0 0 166 185 1 1
FGF21 ACOT4 0 0 214 231 1 1
FGF21 IFNG 0 0 123 312 1 2
FGF21 APOA4 0 900 261 924 1 1
FGF21 IL6 0 0 520 596 1 2
FGF21 LYPD3 0 0 54 389 1 1
FGF21 NALCN 0 0 0 161 1 1
FGF21 PLIN1 0 0 469 469 1 1
FGF21 ACAN 0 0 52 266 1 1
FGF21 MPO 0 0 107 162 1 2
FGF21 UCP2 0 0 459 462 1 2
FGF21 MYOG 0 0 144 230 1 1
FGF21 RPS6 0 0 138 161 1 2
FGF21 CYP4A11 0 0 134 207 1 1
FGF21 CYP4A22 0 0 125 199 1 1
FGF21 STAT1 0 0 57 264 1 2
FGF21 VNN1 0 0 233 249 1 1
FGF21 ENSG00000278882 0 0 0 201 1 1
FGF21 MMP1 0 0 0 288 1 1
FGF21 NOTCH1 0 0 98 476 1 2
FGF21 CXCR4 0 0 67 320 1 2
FGF21 FGF13 0 0 423 173 1 1
FGF21 ABCB11 0 0 184 202 1 1
FGF21 OSTN 0 0 341 341 1 1
FGF21 BMP3 0 0 0 424 1 1
FGF21 ACOT2 0 0 290 298 1 1
FGF21 POTEF 0 0 106 197 1 1
FGF21 MTOR 0 0 417 466 1 2
FGF21 TRPV1 0 0 107 162 1 2
FGF21 SCN1A 0 0 0 161 1 1
FGF21 MIER3 0 0 0 189 1 1
FGF21 LIPE 0 0 558 563 1 1
FGF21 EPHA2 0 600 0 602 1 1
FGF21 EGR1 0 0 335 359 1 2
FGF21 RETSAT 0 0 181 186 1 1
FGF21 APP 0 0 86 166 1 2
FGF21 MFN2 0 0 287 286 1 2
FGF21 SOCS7 0 0 53 267 1 1
FGF21 MYF5 0 0 381 384 1 1
FGF21 HRAS 0 0 67 337 1 2
FGF21 CTNNB1 0 0 193 541 1 2
FGF21 ACSL5 0 0 195 195 1 1
FGF21 CACNA1C 0 0 0 324 1 1
FGF21 COQ9 0 0 114 205 1 1
FGF21 WNT2B 0 0 48 349 1 1
FGF21 PSAT1 0 0 232 233 1 1
FGF21 IL1B 0 0 372 466 1 2
FGF21 NR1H3 0 0 235 329 1 1
FGF21 GCK 0 0 391 404 1 1
FGF21 SIRT5 0 0 369 369 1 1
FGF21 EDN1 0 0 126 362 1 1
FGF21 HIF1A 0 0 266 344 1 2
FGF21 CYP27B1 0 0 233 248 1 1
FGF21 ISL1 0 0 0 179 1 1
FGF21 WNT7B 0 0 62 160 1 1
FGF21 PAX2 0 0 0 151 1 1
FGF21 SLC1A7 0 0 170 169 1 1
FGF21 PEX11A 0 0 195 226 1 1
FGF21 CXCL8 0 0 260 424 1 2
FGF21 ID1 0 0 0 254 1 1
FGF21 DARS2 0 0 233 232 1 1
FGF21 EXT1 0 0 0 190 1 1
FGF21 MMP15 0 0 0 368 1 1
FGF21 ERN1 0 0 260 260 1 2
FGF21 CPT2 0 0 456 456 1 1
FGF21 HBEGF 0 0 73 168 1 1
FGF21 PLIN4 0 0 205 205 1 1
FGF21 GDNF 0 0 95 466 1 2
FGF21 STAT3 0 0 306 424 1 2
FGF21 POU5F1B 0 0 0 290 1 1
FGF21 EIF2AK4 0 0 505 513 1 2
FGF21 RBM3 0 0 167 167 1 1
FGF21 CACNA1D 0 0 0 235 1 1
FGF21 CDH2 0 0 45 299 1 1
FGF21 PTX3 0 0 95 166 1 1
FGF21 STYK1 0 0 0 198 1 1
FGF21 WNT5B 0 0 81 208 1 1
FGF21 GHRL 0 0 521 524 1 1
FGF21 JAK2 0 0 212 266 1 2
FGF21 CACNA1F 0 0 0 235 1 1
FGF21 PPARD 0 0 81 297 1 1
FGF21 KLF10 0 0 138 178 1 1
FGF21 CDH3 0 0 0 234 1 1
FGF21 CISD2 0 0 134 167 1 2
FGF21 NR4A1 0 0 218 218 1 2
FGF21 HK2 0 0 137 178 1 2
FGF21 FGF7 0 0 370 210 1 1
FGF21 PITX2 0 0 0 173 1 1
FGF21 SLC2A2 0 0 305 320 1 1
FGF21 NCOR2 0 0 113 152 1 1
FGF21 CSF3 0 0 85 334 1 1
FGF21 TNFRSF11B 0 0 166 258 1 1
FGF21 HOXC9 0 0 229 228 1 1
FGF21 PNLIP 0 0 140 232 1 1
FGF21 WNT4 0 0 46 178 1 1
FGF21 DDIT3 0 0 325 339 1 2
FGF21 FGFR1OP 0 0 91 157 1 1
FGF21 HMGCS1 0 0 262 270 1 1
FGF21 INSIG1 0 0 229 228 1 1
FGF21 NR1H2 0 0 105 243 1 1
FGF21 DHH 0 0 0 343 1 1
FGF21 LEPROT 0 0 286 291 1 1
FGF21 DCN 0 0 87 251 1 2
FGF21 TP53 0 0 234 312 1 2
FGF21 LCN2 0 0 251 250 1 1
FGF21 METAP2 0 0 161 161 1 1
FGF21 EGFR 0 600 135 737 1 2
FGF21 MOGAT1 0 0 200 217 1 1
FGF21 SLC2A1 0 0 458 457 1 2
FGF21 FFAR1 0 0 150 169 1 1
FGF21 FGFR3 0 600 557 906 1 1
FGF21 ZNF423 0 0 151 164 1 1
FGF21 CIDEA 0 0 657 669 1 1
FGF21 SLC25A19 0 0 391 390 1 1
FGF21 FRS2 0 0 445 501 1 1
FGF21 AKT2 0 0 210 265 1 2
FGF21 NFE2L2 0 0 324 323 1 2
FGF21 NKX6-1 0 0 81 152 1 1
FGF21 MAP3K8 0 0 69 168 1 1
FGF21 MAP2K1 0 0 97 195 1 1
FGF21 OSM 0 0 141 326 1 1
FGF21 NPY 0 0 358 367 1 1
FGF21 STK11 0 0 289 288 1 2
FGF21 PDGFB 0 0 51 266 1 2
FGF21 CACNA1S 0 0 72 345 1 1
FGF21 SMAD4 0 0 60 230 1 2
FGF21 LRP5 0 0 60 157 1 1
FGF21 TNFRSF12A 0 0 0 468 1 1
FGF21 HDAC3 0 0 193 194 1 2
FGF21 ACSL1 0 0 283 282 1 1
FGF21 EBF2 0 0 282 283 1 1
FGF21 DUSP4 0 0 90 154 1 1
FGF21 NUPR1 0 0 235 235 1 2
FGF21 SCN2A 0 0 0 161 1 1
FGF21 GPR50 0 0 82 253 1 1
FGF21 CYP7B1 0 0 261 289 1 1
FGF21 NOG 0 0 0 250 1 1
FGF21 MAP2 0 0 0 189 1 2
FGF21 G6PC 0 0 606 627 1 1
FGF21 ACACA 0 0 455 459 1 1
FGF21 MMP17 0 0 0 369 1 1
FGF21 NR1I3 0 0 203 220 1 1
FGF21 GFRAL 0 0 242 241 1 1
FGF21 WNT5A 0 0 57 212 1 2
FGF21 IL18 0 0 151 222 1 2
FGF21 CLOCK 0 0 212 212 1 2
FGF21 NR0B2 0 0 377 402 1 1
FGF21 RXFP2 0 0 0 242 1 1
FGF21 PAX7 0 0 175 225 1 1
FGF21 IL15 0 0 322 334 1 1
FGF21 PDSS2 0 0 134 222 1 1
FGF21 KLB 417 0 989 994 1 1
FGF21 MYC 0 0 123 390 1 2
FGF21 KISS1R 0 0 82 177 1 1
FGF21 DGAT1 0 0 341 345 1 2
FGF21 PPIG 0 0 143 196 1 1
FGF21 FGFBP1 0 0 96 171 1 1
FGF21 FGF10 0 0 391 173 1 1
FGF21 PCK1 0 0 507 536 1 1
FGF21 PPARGC1A 0 0 739 740 1 2
FGF21 SDHC 0 0 150 210 1 1
FGF21 PLTP 0 0 151 150 1 1
FGF21 IGF1R 0 600 117 701 1 2
FGF21 IL36G 0 0 0 298 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0005104 Molecular Function fibroblast growth factor receptor binding enables IBA
GO:0008083 Molecular Function growth factor activity enables IBA
GO:0005515 Molecular Function protein binding enables IPI
GO:0009887 Biological Process animal organ morphogenesis involved_in IBA
GO:0030154 Biological Process cell differentiation involved_in IBA
GO:0007267 Biological Process cell-cell signaling involved_in TAS
GO:0071377 Biological Process cellular response to glucagon stimulus involved_in IEA
GO:0071333 Biological Process cellular response to glucose stimulus involved_in IEA
GO:0071404 Biological Process cellular response to low-density lipoprotein particle stimulus involved_in IEA
GO:0071466 Biological Process cellular response to xenobiotic stimulus involved_in IEA
GO:0030968 Biological Process endoplasmic reticulum unfolded protein response involved_in IEA
GO:0072577 Biological Process endothelial cell apoptotic process involved_in IEA
GO:0008543 Biological Process fibroblast growth factor receptor signaling pathway involved_in IBA
GO:2000352 Biological Process negative regulation of endothelial cell apoptotic process involved_in IEA
GO:0070374 Biological Process positive regulation of ERK1 and ERK2 cascade involved_in IDA
GO:0090080 Biological Process positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway involved_in IEA
GO:0008284 Biological Process positive regulation of cell population proliferation involved_in IBA
GO:0120162 Biological Process positive regulation of cold-induced thermogenesis involved_in ISS
GO:0010628 Biological Process positive regulation of gene expression involved_in IBA
GO:0046326 Biological Process positive regulation of glucose import involved_in IDA
GO:1905599 Biological Process positive regulation of low-density lipoprotein receptor activity acts_upstream_of NAS
GO:0001934 Biological Process positive regulation of protein phosphorylation involved_in IBA
GO:0010898 Biological Process positive regulation of triglyceride catabolic process involved_in IEA
GO:0030334 Biological Process regulation of cell migration involved_in IBA
GO:0010988 Biological Process regulation of low-density lipoprotein particle clearance acts_upstream_of NAS
GO:0014823 Biological Process response to activity involved_in IEA
GO:1904640 Biological Process response to methionine involved_in IEA
GO:0031667 Biological Process response to nutrient levels involved_in IEA
GO:0007165 Biological Process signal transduction involved_in TAS
GO:0005737 Cellular Component cytoplasm is_active_in IBA
GO:0005576 Cellular Component extracellular region located_in TAS
GO:0005615 Cellular Component extracellular space is_active_in IBA
Pathways
Name DB ID
Plasma lipoprotein assembly, remodeling, and clearance Reactome R-HSA-174824
Cellular hexose transport Reactome R-HSA-189200
Transport of small molecules Reactome R-HSA-382551
SLC-mediated transmembrane transport Reactome R-HSA-425407
Assembly of active LPL and LIPC lipase complexes Reactome R-HSA-8963889
Plasma lipoprotein remodeling Reactome R-HSA-8963899
Thermogenesis (WP4321) WikiPathways WP4321_r123362
Breast cancer pathway (WP4262) WikiPathways WP4262_r123349
Thyroid hormones production and peripheral downstream signaling effects (WP4746) WikiPathways WP4746_r123317
Sterol regulatory element-binding proteins (SREBP) signaling (WP1982) WikiPathways WP1982_r116442
Aryl hydrocarbon receptor pathway (WP2586) WikiPathways WP2586_r121728
Regulation of actin cytoskeleton (WP51) WikiPathways WP51_r116716
Focal adhesion: PI3K-Akt-mTOR-signaling pathway (WP3932) WikiPathways WP3932_r124527
MAPK signaling pathway (WP382) WikiPathways WP382_r119087
Malignant pleural mesothelioma (WP5087) WikiPathways WP5087_r122659
PI3K-Akt signaling pathway (WP4172) WikiPathways WP4172_r122580
Embryonic stem cell pluripotency pathways (WP3931) WikiPathways WP3931_r117717
Transcripts
Accession Version MolecularType Name NCBI Comments
NM_019113 4 mRNA None NC_000019 Reference