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GDNF

glial cell derived neurotrophic factor
General Information
Name glial cell derived neurotrophic factor
Alias
  • glial cell line-derived neurotrophic factor
  • astrocyte-derived trophic factor
Gene_family GDNF family ligands
organism Homo sapiens
entrez_id 2668
location 5p13.2
transcript_count 6
exon_count 6
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The recombinant form of this protein, a highly conserved neurotrophic factor, was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. This protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Mutations in this gene may be associated with Hirschsprung disease and Tourette syndrome. This gene encodes multiple protein isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Aug 2016]
    Stringdb Glial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake; Belongs to the TGF-beta family. GDNF subfamily
    nextProt Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
GDNF BioGRID RANBP10 GeneID BioGRID Affinity Capture-MS
GDNF BioGRID ARMC8 GeneID BioGRID Affinity Capture-MS
GDNF BioGRID MAEA GeneID BioGRID Affinity Capture-MS
GDNF BioGRID GID4 GeneID BioGRID Affinity Capture-MS
GDNF BioGRID DDX39A GeneID BioGRID Affinity Capture-RNA
GDNF BioGRID RIGI GeneID BioGRID Affinity Capture-RNA
GDNF BioGRID KIF20A GeneID BioGRID Affinity Capture-MS
GDNF BioGRID RET GeneID BioGRID Affinity Capture-MS
GDNF BioGRID PTPRA GeneID BioGRID Affinity Capture-MS
GDNF BioGRID GDNF GeneID BioGRID Affinity Capture-MS
GDNF BioGRID SCAMP5 GeneID BioGRID Two-hybrid
GDNF BioGRID AGO2 GeneID BioGRID Affinity Capture-RNA
GDNF BioGRID SYP GeneID BioGRID Two-hybrid
GDNF BioGRID MUC1 GeneID BioGRID Two-hybrid
GDNF BioGRID ETAA1 GeneID BioGRID Synthetic Lethality
GDNF BioGRID AGTRAP GeneID BioGRID Two-hybrid
GDNF BioGRID PTPRE GeneID BioGRID Affinity Capture-MS
GDNF BioGRID RMND5A GeneID BioGRID Affinity Capture-MS
GDNF BioGRID YPEL5 GeneID BioGRID Affinity Capture-MS
GDNF BioGRID RANBP9 GeneID BioGRID Affinity Capture-MS
GDNF BioGRID S100A10 GeneID BioGRID Affinity Capture-MS
GDNF BioGRID MKLN1 GeneID BioGRID Affinity Capture-MS
GDNF BioGRID COPS5 GeneID BioGRID Affinity Capture-MS
GDNF Protein GFRA2 GeneID HPRD
GDNF Protein GFRA1 GeneID HPRD
GDNF Protein GDNF GeneID HPRD
GDNF Protein RET GeneID HPRD
GDNF Protein NCAM1 GeneID HPRD
GDNF BioGRID GFRA2 GeneID BioGRID Reconstituted Complex
GDNF BioGRID GFRA1 GeneID BioGRID Reconstituted Complex
StringDB
A B experiments database textmining combined score hadb nhadb
GDNF PGF 0 0 320 333 1 1
GDNF SCN8A 0 0 266 266 1 1
GDNF SEMA5A 0 0 341 341 1 1
GDNF FZD5 0 0 72 215 1 1
GDNF FOXC1 0 0 289 304 1 1
GDNF SIGMAR1 0 0 216 216 1 1
GDNF GABBR1 0 0 157 156 1 1
GDNF CD86 0 0 143 173 1 1
GDNF TACR1 0 0 228 227 1 1
GDNF CNP 0 0 218 231 1 1
GDNF TLR2 0 0 235 235 1 2
GDNF PIK3CB 0 600 49 603 1 1
GDNF BCAN 0 0 181 181 1 1
GDNF FLT4 0 0 181 181 1 1
GDNF FGF23 0 0 64 160 1 1
GDNF MET 0 0 220 220 1 2
GDNF ELAVL4 0 0 194 194 1 1
GDNF GRIN2B 0 0 329 329 1 1
GDNF LRRK2 0 0 401 417 1 2
GDNF AMH 0 0 361 361 1 1
GDNF CYP11A1 0 0 143 162 1 1
GDNF PTF1A 0 0 91 156 1 1
GDNF SDC1 0 0 175 175 1 1
GDNF THBS1 0 0 209 226 1 1
GDNF NTN4 0 0 143 166 1 1
GDNF MAOB 0 0 470 479 1 1
GDNF BECN1 0 0 193 193 1 2
GDNF MAPT 0 0 341 341 1 2
GDNF CCL7 0 0 248 248 1 1
GDNF SCAMP5 427 0 0 435 1 1
GDNF IRX3 0 0 181 198 1 1
GDNF ALDH1A1 0 0 136 154 1 1
GDNF SFRP2 0 0 172 171 1 1
GDNF FZD3 0 0 165 177 1 1
GDNF IL2 0 0 260 260 1 1
GDNF GFRA3 0 500 558 918 1 1
GDNF FOXO1 0 0 207 207 1 2
GDNF KRAS 0 0 112 212 1 2
GDNF FOXD1 0 0 405 425 1 1
GDNF NANOS2 0 0 505 515 1 1
GDNF CBLN1 0 0 180 179 1 1
GDNF PTH 0 0 141 180 1 1
GDNF SVIL 0 0 0 190 1 1
GDNF SOD2 0 0 170 169 1 2
GDNF HSPA5 0 0 187 187 1 2
GDNF PDYN 0 0 234 234 1 1
GDNF FGF20 0 0 323 369 1 1
GDNF CAMK4 0 0 90 174 1 1
GDNF MTPN 0 0 0 210 1 1
GDNF ASCL1 0 0 470 470 1 1
GDNF SOHLH1 0 0 456 456 1 1
GDNF INHBB 0 0 163 364 1 1
GDNF GAB1 0 900 141 910 1 1
GDNF AQP4 0 0 387 386 1 1
GDNF PTPN11 0 900 184 914 1 1
GDNF MSTN 0 0 123 217 1 1
GDNF TWIST1 0 0 442 455 1 1
GDNF SNCB 0 0 150 186 1 1
GDNF FASLG 0 0 225 224 1 1
GDNF SV2A 0 0 244 243 1 1
GDNF FOS 0 0 469 469 1 2
GDNF GDF6 0 0 95 258 1 1
GDNF SOCS3 0 0 155 154 1 1
GDNF WNT3 0 0 180 179 1 1
GDNF PHC3 0 0 166 165 1 1
GDNF PROKR2 0 0 202 202 1 1
GDNF FGF11 0 0 64 439 1 1
GDNF HPSE2 0 0 112 166 1 1
GDNF LRCH4 0 0 81 150 1 1
GDNF KCNJ10 0 0 247 246 1 1
GDNF HDAC1 0 0 233 232 1 2
GDNF CSF1 0 0 370 383 1 1
GDNF BCL6B 0 0 673 680 1 1
GDNF GHR 0 0 63 225 1 1
GDNF ADAM28 0 0 125 156 1 1
GDNF TSPO 0 0 185 185 1 1
GDNF DHFR 0 0 109 156 1 1
GDNF FGF9 0 0 391 456 1 1
GDNF PIK3CD 0 600 0 600 1 1
GDNF SOX1 0 0 413 425 1 1
GDNF GPR126 0 0 112 207 1 1
GDNF NTF3 0 0 856 877 1 1
GDNF WNT2 0 0 251 365 1 1
GDNF EPHB2 0 0 211 211 1 2
GDNF ZFP90 0 0 180 179 1 1
GDNF CDKN2A 0 0 193 193 1 2
GDNF KCNQ2 0 0 165 165 1 1
GDNF BMPR1B 0 0 113 173 1 1
GDNF SST 0 0 379 379 1 1
GDNF GUSB 0 0 150 168 1 1
GDNF LHX6 0 0 181 181 1 1
GDNF FGF8 0 0 607 653 1 1
GDNF SALL4 0 0 287 286 1 1
GDNF EPSTI1 0 0 0 189 1 1
GDNF PLXND1 0 0 136 207 1 1
GDNF S100B 0 0 561 561 1 1
GDNF FAT4 0 0 157 175 1 1
GDNF TTR 0 0 123 274 1 1
GDNF GSK3B 0 0 241 300 1 2
GDNF MRC1 0 0 208 208 1 1
GDNF VEGFC 0 0 240 256 1 1
GDNF CYBB 0 0 162 161 1 2
GDNF CXCL5 0 0 184 183 1 1
GDNF GRM1 0 0 193 193 1 1
GDNF PPIA 0 0 166 165 1 1
GDNF OSR2 0 0 113 166 1 1
GDNF GDF11 0 0 297 310 1 1
GDNF NOTCH2 0 0 193 193 1 1
GDNF ACE 0 0 181 181 1 1
GDNF FGF22 0 0 90 455 1 1
GDNF ANG 0 0 334 344 1 2
GDNF IHH 0 0 135 150 1 1
GDNF BCAR1 0 900 55 901 1 1
GDNF REN 0 0 219 219 1 1
GDNF SLC1A1 0 0 181 181 1 1
GDNF IL13 0 0 261 261 1 2
GDNF AFP 0 0 159 177 1 2
GDNF FIGF 0 0 181 181 1 1
GDNF EPHA5 0 0 123 318 1 1
GDNF CCL11 0 0 154 153 1 1
GDNF CYP26A1 0 0 193 193 1 1
GDNF PTGS2 0 0 336 354 1 2
GDNF FGF19 0 0 123 474 1 1
GDNF ERBB3 0 0 268 286 1 1
GDNF CASP3 0 0 518 540 1 2
GDNF CXCL1 0 0 230 229 1 2
GDNF P2RX3 0 0 505 505 1 1
GDNF CYP26B1 0 0 265 281 1 1
GDNF MMP14 0 0 309 309 1 1
GDNF TRPV3 0 0 187 187 1 1
GDNF VEGFA 0 0 681 683 1 2
GDNF FZD9 0 0 103 159 1 1
GDNF CHL1 0 0 975 975 1 1
GDNF MAPK7 0 600 231 679 1 1
GDNF SALL1 0 0 517 538 1 1
GDNF MBP 0 0 468 484 1 2
GDNF BMPR1A 0 0 181 256 1 1
GDNF PTEN 0 0 294 294 1 2
GDNF MAEA 571 0 0 571 1 1
GDNF MAGEA4 0 0 162 174 1 1
GDNF HECW2 0 0 150 186 1 1
GDNF MYOD1 0 0 257 256 1 1
GDNF KLHL30 0 0 123 161 1 1
GDNF PI4KB 0 0 388 388 1 1
GDNF NTRK3 0 0 697 703 1 1
GDNF DRD3 0 0 180 203 1 1
GDNF CD200 0 0 213 213 1 1
GDNF TCF4 0 0 171 171 1 1
GDNF BMP4 0 0 561 568 1 1
GDNF HOXC11 0 0 170 189 1 1
GDNF RARB 0 0 146 168 1 1
GDNF WT1 0 0 490 516 1 1
GDNF MKLN1 430 0 0 430 1 1
GDNF KIT 0 0 491 491 1 2
GDNF NFKBIA 0 0 181 181 1 2
GDNF LEP 0 0 246 245 1 1
GDNF PAX1 0 0 65 162 1 1
GDNF ARTN 0 500 868 640 1 1
GDNF CFL1 0 0 162 161 1 1
GDNF MAPK14 0 0 193 222 1 2
GDNF RANBP10 480 0 0 480 1 1
GDNF IAH1 0 0 469 469 1 1
GDNF POU4F3 0 0 186 186 1 1
GDNF ENSG00000258947 0 0 405 534 1 1
GDNF MAPK10 0 0 162 174 1 2
GDNF NGFR 0 0 566 582 1 1
GDNF HOXD11 0 0 321 321 1 1
GDNF IGF2 0 0 369 369 1 1
GDNF RAP1GAP 0 600 75 614 1 1
GDNF CTSD 0 0 165 165 1 2
GDNF SHC1 0 900 468 944 1 1
GDNF SFRP1 0 0 232 231 1 1
GDNF DRD5 0 0 157 156 1 1
GDNF NTF4 0 0 769 783 1 1
GDNF GAD2 0 0 310 309 1 1
GDNF RET 848 900 989 999 1 1
GDNF SOX10 0 0 572 581 1 1
GDNF LHCGR 0 0 134 173 1 1
GDNF SEMA3E 0 0 359 359 1 1
GDNF ENG 0 0 339 339 1 2
GDNF CCL3 0 0 261 261 1 1
GDNF FGF12 0 0 90 331 1 1
GDNF TAC1 0 0 556 556 1 1
GDNF TJP1 0 0 325 325 1 1
GDNF TGFBR2 0 0 125 157 1 1
GDNF DMD 0 0 139 158 1 2
GDNF FOSB 0 0 261 261 1 1
GDNF GDF5 0 0 284 284 1 1
GDNF FOSL2 0 0 202 202 1 1
GDNF GDF15 0 0 405 409 1 1
GDNF DLG4 0 0 394 394 1 2
GDNF ACTG1 0 0 241 258 1 1
GDNF NCK1 0 900 74 906 1 1
GDNF GFAP 0 0 654 666 1 2
GDNF SEMA6B 0 0 341 341 1 1
GDNF GFRA1 971 900 990 999 1 1
GDNF FGFR4 0 0 122 150 1 1
GDNF EFNB2 0 0 186 203 1 1
GDNF DBH 0 0 360 361 1 1
GDNF IL10 0 0 460 493 1 2
GDNF CCL20 0 0 181 181 1 1
GDNF FLT3 0 0 181 181 1 2
GDNF COL1A1 0 0 125 231 1 2
GDNF SDC3 0 0 915 915 1 1
GDNF TGFBR1 0 0 155 189 1 1
GDNF GALC 0 0 324 323 1 1
GDNF NKX2-1 0 0 267 267 1 1
GDNF RLBP1 0 0 155 154 1 1
GDNF HSPB1 0 0 215 215 1 2
GDNF NINJ1 0 0 217 217 1 1
GDNF GLI1 0 0 242 241 1 2
GDNF TERT 0 0 134 152 1 2
GDNF HSPB2 0 0 194 194 1 1
GDNF MCAM 0 0 171 189 1 1
GDNF STRA8 0 0 501 509 1 1
GDNF UBC 0 0 193 198 1 2
GDNF SERPINB5 0 0 134 223 1 1
GDNF SH3BGRL3 0 0 81 159 1 1
GDNF SDC2 0 0 141 171 1 1
GDNF TIMP2 0 0 172 190 1 1
GDNF EFNA2 0 0 202 202 1 1
GDNF NRTN 0 300 917 426 1 1
GDNF PCDH11X 0 0 164 163 1 1
GDNF HAND2 0 0 261 261 1 1
GDNF PRKCA 0 900 188 915 1 1
GDNF DACH1 0 0 308 307 1 1
GDNF DLX1 0 0 184 183 1 1
GDNF NCAM1 213 500 953 980 1 1
GDNF CAMK2A 0 0 151 150 1 2
GDNF VTN 0 0 233 232 1 1
GDNF FN1 0 0 520 547 1 2
GDNF GAL 0 0 340 340 1 1
GDNF MUSK 0 0 240 239 1 1
GDNF GPX1 0 0 151 150 1 1
GDNF RARA 0 0 156 155 1 2
GDNF RARS 0 0 190 190 1 1
GDNF RCOR1 0 0 124 171 1 1
GDNF ADK 0 0 150 177 1 1
GDNF CTSB 0 0 139 151 1 2
GDNF PRL 0 0 202 202 1 1
GDNF CTF1 0 0 375 375 1 1
GDNF SIRT1 0 0 240 239 1 2
GDNF OPTN 0 0 155 213 1 2
GDNF ITGAM 0 0 325 336 1 1
GDNF TRPA1 0 0 459 459 1 1
GDNF HOMER1 0 0 162 163 1 1
GDNF GATA2 0 0 241 241 1 1
GDNF BACE1 0 0 285 284 1 2
GDNF SMAD7 0 0 109 198 1 1
GDNF RCVRN 0 0 138 168 1 1
GDNF EN1 0 0 452 463 1 1
GDNF IFNB1 0 0 170 169 1 1
GDNF NCL 0 0 93 326 1 2
GDNF HMGB1 0 0 156 155 1 2
GDNF ESR1 0 0 325 325 1 2
GDNF SPIN4 0 0 90 163 1 1
GDNF PTPRA 414 0 81 438 1 1
GDNF WNT3A 0 0 323 323 1 2
GDNF SYP 115 0 494 542 1 1
GDNF INHA 0 0 135 206 1 1
GDNF GRIN1 0 0 217 230 1 1
GDNF LGR5 0 0 167 205 1 1
GDNF BMP8A 0 0 112 155 1 1
GDNF CRH 0 0 246 245 1 1
GDNF OTX2 0 0 394 394 1 1
GDNF GRM2 0 0 247 246 1 1
GDNF TPPP 0 0 180 179 1 1
GDNF SLC6A3 0 0 602 602 1 1
GDNF FUS 0 0 298 298 1 2
GDNF SEMA6C 0 0 339 339 1 1
GDNF GPR88 0 0 44 187 1 1
GDNF MANF 0 0 602 626 1 1
GDNF PTPRZ1 0 0 212 212 1 1
GDNF SEMA4D 0 0 325 325 1 1
GDNF SIX1 0 0 467 533 1 1
GDNF PMP22 0 0 204 221 1 1
GDNF EYA1 0 0 564 610 1 1
GDNF PRDM5 0 0 213 254 1 1
GDNF MSX1 0 0 218 235 1 1
GDNF TNF 0 0 509 539 1 2
GDNF SNAP25 0 0 253 252 1 1
GDNF MMP3 0 0 181 233 1 1
GDNF GPC2 0 0 235 235 1 1
GDNF VDR 0 0 240 239 1 2
GDNF WISP1 0 0 120 150 1 1
GDNF PIK3R2 0 600 52 604 1 1
GDNF KCND2 0 0 295 295 1 1
GDNF SIX3 0 0 181 181 1 1
GDNF NR4A2 0 0 603 627 1 1
GDNF BDNF 0 0 912 950 1 2
GDNF MEF2C 0 0 161 161 1 1
GDNF CD44 0 0 329 329 1 2
GDNF NT5E 0 0 306 311 1 1
GDNF VAPB 0 0 91 177 1 1
GDNF GPR125 0 0 408 418 1 1
GDNF IL7 0 0 161 161 1 1
GDNF GPC1 0 0 251 250 1 1
GDNF KIAA1279 0 0 406 415 1 1
GDNF CARF 0 0 330 330 1 1
GDNF ATP13A2 0 0 156 155 1 1
GDNF GPC5 0 0 212 212 1 1
GDNF MMP7 0 0 323 323 1 1
GDNF PAX3 0 0 310 309 1 1
GDNF NFAT5 0 0 74 158 1 1
GDNF ASIC2 0 0 170 169 1 1
GDNF TFAP2C 0 0 160 159 1 1
GDNF ACVR2A 0 0 71 232 1 1
GDNF NXNL1 0 0 212 212 1 1
GDNF RBFOX3 0 0 603 603 1 1
GDNF FMR1 0 0 150 171 1 1
GDNF GRM4 0 0 167 167 1 1
GDNF GCG 0 0 194 194 1 1
GDNF PTCH1 0 0 283 282 1 1
GDNF PLXNB2 0 0 300 388 1 1
GDNF SOS1 0 900 57 901 1 1
GDNF SPRY2 0 0 165 182 1 1
GDNF TNFAIP6 0 0 162 161 1 1
GDNF CCND2 0 0 156 242 1 1
GDNF TFAP2A 0 0 226 225 1 1
GDNF TFRC 0 0 263 263 1 1
GDNF VWF 0 0 181 181 1 1
GDNF RAPSN 0 0 181 198 1 1
GDNF IL5 0 0 194 194 1 1
GDNF IGFBP6 0 0 171 171 1 1
GDNF SLC17A8 0 0 162 161 1 1
GDNF SNCG 0 0 133 151 1 1
GDNF CD9 0 0 244 254 1 1
GDNF FGF2 0 0 802 836 1 2
GDNF ATF3 0 0 555 555 1 2
GDNF CDH5 0 0 188 188 1 1
GDNF AGTRAP 206 0 0 206 1 1
GDNF NRN1 0 0 249 248 1 1
GDNF CNR1 0 0 233 232 1 1
GDNF KIF26B 0 0 230 246 1 1
GDNF THBS2 0 0 193 211 1 1
GDNF MERTK 0 0 193 194 1 1
GDNF SIX5 0 0 193 216 1 1
GDNF CSF1R 0 0 241 240 1 1
GDNF ITGA3 0 0 95 194 1 2
GDNF IGF1 0 0 683 704 1 2
GDNF MAPK1 0 0 219 230 1 2
GDNF SNF8 0 0 67 167 1 1
GDNF RIC8B 0 0 255 268 1 1
GDNF IDUA 0 0 194 194 1 1
GDNF SERPINE1 0 0 210 227 1 1
GDNF UPK3A 0 0 134 156 1 1
GDNF REM1 0 0 0 179 1 1
GDNF AGTR1 0 0 156 155 1 1
GDNF GPC6 0 0 210 210 1 1
GDNF OLIG2 0 0 469 469 1 1
GDNF ADRB2 0 0 145 236 1 1
GDNF HOXC6 0 0 122 153 1 1
GDNF CRLF1 0 0 204 221 1 1
GDNF RPS6KB1 0 0 202 202 1 2
GDNF EGR2 0 0 375 388 1 1
GDNF RRAD 0 0 181 186 1 1
GDNF DRD1 0 0 215 224 1 1
GDNF LOX 0 0 210 228 1 2
GDNF SCN11A 0 0 390 390 1 1
GDNF IRS1 0 900 171 913 1 2
GDNF CBL 0 0 129 232 1 1
GDNF EPHB1 0 0 144 163 1 1
GDNF EDNRA 0 0 357 357 1 1
GDNF NTRK1 0 0 986 987 1 1
GDNF EPOR 0 0 211 212 1 1
GDNF ASIC1 0 0 174 174 1 2
GDNF MEGF10 0 0 134 214 1 1
GDNF PTPRE 397 0 0 396 1 1
GDNF WNT9A 0 0 155 236 1 1
GDNF FGF5 0 0 255 350 1 1
GDNF WNT8B 0 0 155 154 1 1
GDNF GREM2 0 0 73 248 1 1
GDNF PDLIM7 0 900 0 900 1 1
GDNF FOXC2 0 0 219 236 1 1
GDNF SERPINE2 0 0 137 171 1 1
GDNF GID4 497 0 0 497 1 1
GDNF EPHA1 0 0 218 218 1 1
GDNF SEMA3A 0 0 459 459 1 1
GDNF JUND 0 0 260 260 1 1
GDNF NOS3 0 0 244 243 1 2
GDNF ACTA2 0 0 108 170 1 1
GDNF FSHR 0 0 250 361 1 1
GDNF CCND1 0 0 262 281 1 2
GDNF AGXT 0 0 95 298 1 1
GDNF CACNA1B 0 0 212 212 1 1
GDNF HOXB7 0 0 391 390 1 1
GDNF GBA 0 0 134 157 1 1
GDNF PHOX2B 0 0 563 572 1 1
GDNF SEMA4G 0 0 334 334 1 1
GDNF LIN28A 0 0 391 390 1 1
GDNF KCND1 0 0 357 357 1 1
GDNF SMAD6 0 0 87 252 1 1
GDNF FOXA2 0 0 404 417 1 1
GDNF MDK 0 0 261 262 1 1
GDNF SEMA5B 0 0 336 336 1 1
GDNF SPRY1 0 0 420 478 1 1
GDNF FGF16 0 0 67 320 1 1
GDNF HPRT1 0 0 269 269 1 1
GDNF RHEB 0 0 144 163 1 2
GDNF DDIT4 0 0 143 161 1 2
GDNF ATF7 0 0 377 377 1 1
GDNF SMN2 0 0 233 232 1 1
GDNF POU5F1 0 0 530 555 1 2
GDNF GCH1 0 0 218 219 1 1
GDNF HGF 0 0 556 562 1 2
GDNF ENSG00000264813 0 0 181 181 1 1
GDNF BMPR2 0 0 137 169 1 1
GDNF GRIA1 0 0 266 266 1 1
GDNF NPHS2 0 0 187 187 1 2
GDNF RASA1 0 900 0 900 1 1
GDNF OPRM1 0 0 218 218 1 1
GDNF S100A10 152 0 66 174 1 1
GDNF DUSP6 0 0 141 160 1 1
GDNF PDPK1 0 0 113 155 1 2
GDNF IDE 0 0 195 195 1 1
GDNF SYCP3 0 0 335 335 1 1
GDNF PECAM1 0 0 275 275 1 1
GDNF CAT 0 0 369 369 1 2
GDNF WNT10B 0 0 181 181 1 1
GDNF DCX 0 0 506 506 1 1
GDNF NRG1 0 0 603 603 1 2
GDNF SLC6A2 0 0 230 229 1 1
GDNF SLC17A7 0 0 423 422 1 1
GDNF FOXP3 0 0 150 169 1 2
GDNF HMOX1 0 0 335 376 1 2
GDNF TLX3 0 0 127 366 1 1
GDNF DMRT1 0 0 376 389 1 1
GDNF KDR 0 0 492 492 1 2
GDNF NTN1 0 0 360 377 1 1
GDNF AGTR2 0 0 206 259 1 1
GDNF SEMA3F 0 0 382 395 1 1
GDNF TGFB1 0 0 320 345 1 2
GDNF TSC2 0 0 140 158 1 2
GDNF CDH4 0 0 102 200 1 1
GDNF F2R 0 0 113 151 1 1
GDNF MSX2 0 0 141 186 1 1
GDNF ADORA2B 0 0 217 217 1 1
GDNF GLUL 0 0 274 274 1 1
GDNF GPC3 0 0 164 163 1 1
GDNF ASIC3 0 0 294 294 1 1
GDNF CDKN1B 0 0 167 167 1 2
GDNF TRPV4 0 0 235 240 1 1
GDNF PRKCD 0 0 155 154 1 2
GDNF MLF1 0 0 204 223 1 1
GDNF IRX6 0 0 170 169 1 1
GDNF FOXO3 0 0 181 181 1 2
GDNF FEZF2 0 0 147 186 1 1
GDNF LIFR 0 0 270 282 1 1
GDNF TRPV2 0 0 195 213 1 1
GDNF APOE 0 0 310 309 1 2
GDNF KIF5B 0 0 183 183 1 1
GDNF ITGA6 0 0 288 299 1 1
GDNF CHRNA2 0 0 0 189 1 1
GDNF CDC42 0 0 229 228 1 2
GDNF PODXL 0 0 157 163 1 1
GDNF MEOX1 0 0 157 175 1 1
GDNF SORL1 417 0 678 804 1 1
GDNF DKK1 0 0 218 224 1 1
GDNF SRC 0 900 400 939 1 2
GDNF FLT1 0 0 261 261 1 1
GDNF SIM1 0 0 143 162 1 1
GDNF MIF 0 0 161 161 1 2
GDNF LGALS3 0 0 160 166 1 2
GDNF JDP2 0 0 122 186 1 1
GDNF RPE65 0 0 244 243 1 1
GDNF ROBO2 0 0 538 538 1 1
GDNF SEMA4F 0 0 369 369 1 1
GDNF NPNT 0 0 261 341 1 1
GDNF GAD1 0 0 391 390 1 1
GDNF HTR2A 0 0 244 243 1 1
GDNF COMT 0 0 322 321 1 1
GDNF HNF4A 0 0 180 179 1 1
GDNF ADAM23 0 0 166 178 1 1
GDNF POU4F1 0 0 342 342 1 1
GDNF EIF2AK3 0 0 240 239 1 2
GDNF CCK 0 0 147 166 1 1
GDNF GJA1 0 0 325 339 1 1
GDNF ATOH1 0 0 181 181 1 1
GDNF MAG 0 0 366 367 1 1
GDNF GRM5 0 0 210 210 1 1
GDNF CHRD 0 0 174 173 1 1
GDNF PINK1 0 0 337 337 1 2
GDNF NID1 0 0 193 210 1 1
GDNF IL11 0 0 235 235 1 1
GDNF BMP8B 0 0 310 343 1 1
GDNF ID2 0 0 158 157 1 1
GDNF CXCL10 0 0 236 236 1 2
GDNF EDNRB 0 0 689 689 1 1
GDNF RTN4 0 0 451 459 1 1
GDNF HSP90AB1 0 0 0 216 1 2
GDNF PRX 0 0 181 198 1 1
GDNF PABPC4 0 0 0 156 1 1
GDNF FGF3 0 0 90 457 1 1
GDNF CREM 0 0 393 398 1 1
GDNF PITX3 0 0 518 522 1 1
GDNF SLIT3 0 0 456 467 1 1
GDNF INSC 0 0 189 189 1 1
GDNF VEGFB 0 0 219 219 1 1
GDNF TH 0 0 800 820 1 2
GDNF ACVR1B 0 0 134 263 1 1
GDNF RNF213 0 0 389 388 1 1
GDNF MRGPRD 0 0 325 325 1 1
GDNF ERBB2 0 0 262 278 1 2
GDNF NGF 0 0 873 900 1 2
GDNF ECE1 0 0 394 394 1 1
GDNF CD34 0 0 369 369 1 2
GDNF MKI67 0 0 45 180 1 2
GDNF LHX2 0 0 155 154 1 1
GDNF GRIK1 0 0 134 153 1 1
GDNF CSF2 0 0 335 339 1 1
GDNF SLIT2 0 0 427 452 1 1
GDNF PPARG 0 0 261 261 1 2
GDNF TGFB2 0 0 413 430 1 1
GDNF LHX3 0 0 310 309 1 1
GDNF AKT1 0 0 602 614 1 2
GDNF SEMA7A 0 0 325 325 1 1
GDNF SCN9A 0 0 390 390 1 1
GDNF VCAM1 0 0 210 210 1 1
GDNF ATF4 0 0 172 171 1 2
GDNF PRKCG 0 0 171 171 1 1
GDNF CD4 0 0 282 287 1 2
GDNF FOXA1 0 0 150 176 1 1
GDNF ALS2 0 0 163 163 1 1
GDNF KLF4 0 0 456 456 1 2
GDNF CLDN1 0 0 451 451 1 1
GDNF ATF6 0 0 181 181 1 2
GDNF CDH6 0 0 183 183 1 1
GDNF NTRK2 0 0 686 705 1 1
GDNF VIP 0 0 374 378 1 1
GDNF FGFR1 0 0 342 377 1 1
GDNF SEMA6D 0 0 325 325 1 1
GDNF CELSR3 0 0 174 192 1 1
GDNF RUNX2 0 0 170 169 1 2
GDNF ZKSCAN7 0 0 180 179 1 1
GDNF XIAP 0 0 171 171 1 2
GDNF KIF26A 0 0 482 486 1 1
GDNF SDHD 0 0 397 396 1 1
GDNF CST3 0 0 137 154 1 1
GDNF KCNJ6 0 0 391 399 1 1
GDNF DISC1 0 0 185 185 1 1
GDNF JUN 0 0 952 952 1 2
GDNF SCN3A 0 0 264 264 1 1
GDNF PLCG1 0 600 143 642 1 1
GDNF NRG3 0 0 182 181 1 1
GDNF FZD1 0 0 166 220 1 1
GDNF BCL2L11 0 0 155 154 1 2
GDNF CDH17 0 0 334 334 1 1
GDNF CALB1 0 0 464 467 1 1
GDNF DOK4 0 900 204 918 1 1
GDNF NR2F2 0 0 166 165 1 1
GDNF CCL24 0 0 159 158 1 1
GDNF DPYSL2 0 0 270 270 1 1
GDNF CYP19A1 0 0 193 193 1 2
GDNF DOK5 0 900 388 936 1 1
GDNF GFRA4 0 500 501 790 1 1
GDNF ERBB4 0 0 259 269 1 1
GDNF CAV1 0 0 178 195 1 2
GDNF SIX4 0 0 183 183 1 1
GDNF AIF1 0 0 518 518 1 2
GDNF HSPA1A 0 0 142 175 1 1
GDNF COL18A1 0 0 203 203 1 1
GDNF ZBTB16 0 0 560 567 1 1
GDNF DNTT 0 0 382 382 1 1
GDNF SNCA 0 0 607 607 1 2
GDNF PLAT 0 0 134 175 1 1
GDNF TLX2 0 0 65 215 1 1
GDNF GPC4 0 0 212 212 1 1
GDNF CASP1 0 0 181 181 1 2
GDNF NOS1 0 0 390 390 1 1
GDNF RTN4R 0 0 292 292 1 1
GDNF CCNA2 0 0 150 165 1 1
GDNF ANGPT2 0 0 203 231 1 1
GDNF ZP3 0 0 134 155 1 1
GDNF VSNL1 0 0 386 386 1 1
GDNF ID4 0 0 391 396 1 1
GDNF CRK 0 900 52 901 1 1
GDNF ETV1 0 0 219 301 1 1
GDNF NAT8L 0 0 156 217 1 1
GDNF RUNX3 0 0 161 161 1 1
GDNF AGRN 0 0 358 362 1 1
GDNF MMP2 0 0 260 276 1 2
GDNF TREM2 0 0 166 165 1 1
GDNF PRKACB 0 900 0 901 1 1
GDNF P2RY1 0 0 170 169 1 1
GDNF IGFBP3 0 0 259 275 1 2
GDNF DLL1 0 0 181 181 1 1
GDNF BMP6 0 0 211 211 1 1
GDNF IRS2 0 500 74 517 1 1
GDNF UCHL1 0 0 508 538 1 2
GDNF CD8A 0 0 211 211 1 1
GDNF GAP43 0 0 556 576 1 1
GDNF SEMA3G 0 0 333 333 1 1
GDNF NCOA4 0 0 307 307 1 2
GDNF SOD1 0 0 566 566 1 2
GDNF LTA 0 0 162 214 1 1
GDNF CITED1 0 0 315 315 1 1
GDNF SULF1 0 0 529 540 1 1
GDNF SHH 0 0 681 686 1 2
GDNF SOX17 0 0 208 208 1 1
GDNF PNMT 0 0 170 169 1 1
GDNF FGF6 0 0 283 449 1 1
GDNF PENK 0 0 203 203 1 1
GDNF GRB2 0 900 258 922 1 1
GDNF ANK1 0 0 184 183 1 1
GDNF NKX2-2 0 0 242 241 1 1
GDNF GRIN2A 0 0 261 261 1 1
GDNF FYN 0 0 359 423 1 1
GDNF IGFBP4 0 0 200 200 1 1
GDNF TPH2 0 0 170 169 1 1
GDNF ATF7IP 0 0 451 451 1 1
GDNF JAG1 0 0 245 244 1 1
GDNF FST 0 0 218 240 1 1
GDNF ROBO1 0 0 181 181 1 1
GDNF BOLL 0 0 204 204 1 1
GDNF FOXD3 0 0 231 230 1 1
GDNF ICAM1 0 0 253 252 1 2
GDNF PTPRO 0 0 134 193 1 1
GDNF ADORA2A 0 0 293 293 1 1
GDNF NEUROG1 0 0 293 293 1 1
GDNF CD24 0 0 181 181 1 2
GDNF SEMA4B 0 0 338 338 1 1
GDNF SOX9 0 0 340 340 1 1
GDNF ESR2 0 0 233 232 1 1
GDNF LMX1A 0 0 503 516 1 1
GDNF SOHLH2 0 0 394 397 1 1
GDNF PTPRC 0 0 324 340 1 1
GDNF IGFBP2 0 0 283 282 1 1
GDNF SEMA4A 0 0 325 325 1 1
GDNF NIM1K 0 0 123 216 1 1
GDNF POU3F1 0 0 373 373 1 1
GDNF CCL18 0 0 151 150 1 1
GDNF CXCL12 0 0 504 517 1 2
GDNF PLXNA1 0 0 134 205 1 1
GDNF TIMP1 0 0 294 309 1 1
GDNF FGF4 0 0 323 471 1 1
GDNF BAX 0 0 167 167 1 2
GDNF HSD3B1 0 0 156 155 1 1
GDNF TARDBP 0 0 284 284 1 2
GDNF SYN1 0 0 458 457 1 1
GDNF PIWIL1 0 0 150 186 1 1
GDNF RHOA 0 0 267 267 1 2
GDNF SOX8 0 0 164 163 1 1
GDNF AR 0 0 236 236 1 2
GDNF GDF10 0 0 94 330 1 1
GDNF EPCAM 0 0 155 236 1 2
GDNF GNRH1 0 0 180 197 1 1
GDNF GSR 0 0 150 188 1 1
GDNF ETV4 0 0 456 477 1 1
GDNF SOX21 0 0 47 210 1 1
GDNF VSX2 0 0 294 294 1 1
GDNF SPP1 0 0 279 279 1 2
GDNF SLC32A1 0 0 217 217 1 1
GDNF PHOX2A 0 0 539 547 1 1
GDNF SLC16A1 0 0 159 158 1 1
GDNF DNAH11 0 0 308 307 1 1
GDNF GLI3 0 0 203 220 1 1
GDNF JUNB 0 0 134 152 1 1
GDNF FREM1 0 0 163 173 1 1
GDNF ANGPT1 0 0 421 420 1 1
GDNF THY1 0 0 503 518 1 1
GDNF PROM1 0 0 268 274 1 2
GDNF SIRT3 0 0 150 188 1 2
GDNF LRRN1 0 0 95 233 1 1
GDNF ACR 0 0 150 205 1 1
GDNF MAPK3 0 0 470 483 1 2
GDNF RANBP9 484 0 61 494 1 1
GDNF B2M 0 0 194 194 1 1
GDNF MMP9 0 0 371 371 1 2
GDNF PRDM14 0 0 134 153 1 1
GDNF DNMT1 0 0 234 234 1 2
GDNF WDR70 0 0 211 259 1 1
GDNF CD40 0 0 134 152 1 2
GDNF WNT6 0 0 202 219 1 1
GDNF FGF1 0 0 494 495 1 1
GDNF ENSG00000258555 0 0 241 240 1 1
GDNF NEFH 0 0 402 413 1 1
GDNF FOXG1 0 0 317 317 1 1
GDNF ACTB 0 0 520 556 1 2
GDNF INS 0 0 556 556 1 2
GDNF CCL15 0 0 234 234 1 1
GDNF CLDN5 0 0 335 335 1 1
GDNF ABCA4 0 0 135 371 1 1
GDNF CRP 0 0 147 165 1 2
GDNF PSEN1 0 0 342 342 1 2
GDNF SYT1 0 0 182 181 1 1
GDNF NEUROD1 0 0 341 341 1 1
GDNF P2RX2 0 0 260 260 1 1
GDNF SOX2 0 0 543 545 1 2
GDNF DOK6 0 900 489 946 1 1
GDNF HDAC4 0 0 141 153 1 2
GDNF HSP90AA1 0 0 445 445 1 2
GDNF DDX4 0 0 391 402 1 1
GDNF PAX8 0 0 391 429 1 1
GDNF IL3 0 0 210 210 1 1
GDNF FOSL1 0 0 202 202 1 1
GDNF HSPG2 0 0 202 202 1 1
GDNF PGK1 0 0 158 157 1 2
GDNF PVALB 0 0 451 451 1 1
GDNF ITGB1 0 0 513 513 1 1
GDNF PIWIL4 0 0 150 172 1 1
GDNF DSPP 0 0 185 185 1 1
GDNF STMN2 0 0 235 235 1 1
GDNF MME 0 0 193 193 1 1
GDNF IL16 0 0 183 183 1 1
GDNF CD68 0 0 304 304 1 2
GDNF CASP8 0 0 193 193 1 2
GDNF ALB 0 0 558 577 1 2
GDNF CCL2 0 0 423 422 1 2
GDNF CNTFR 0 0 325 333 1 1
GDNF KNG1 0 0 328 328 1 1
GDNF GABRA4 0 0 134 153 1 1
GDNF TBCK 0 0 48 302 1 1
GDNF DOK1 0 900 91 905 1 1
GDNF SMAD3 0 0 160 161 1 2
GDNF ISLR2 0 0 181 182 1 1
GDNF HNF1B 0 0 136 159 1 1
GDNF VAMP2 0 0 113 189 1 1
GDNF SERPINF1 0 0 367 380 1 1
GDNF TUBB3 0 0 425 549 1 1
GDNF CNTF 0 0 857 863 1 1
GDNF CDK5 0 0 297 297 1 2
GDNF SLC17A6 0 0 321 321 1 1
GDNF PDGFRB 0 0 284 299 1 2
GDNF LEF1 0 0 174 173 1 1
GDNF NRCAM 0 0 341 345 1 1
GDNF IL4 0 0 325 341 1 1
GDNF WNT9B 0 0 466 571 1 1
GDNF DDC 0 0 566 584 1 1
GDNF ZEB2 0 0 259 258 1 1
GDNF FZD8 0 0 60 158 1 1
GDNF ALCAM 0 0 164 163 1 1
GDNF PDGFRA 0 0 261 277 1 1
GDNF PLG 0 0 277 298 1 1
GDNF MLN 0 0 167 167 1 2
GDNF CADPS 0 0 359 359 1 1
GDNF BMP7 0 0 460 470 1 1
GDNF SYCP1 0 0 165 165 1 1
GDNF SCARA5 0 0 159 158 1 1
GDNF FGF17 0 0 184 335 1 1
GDNF CDH1 0 900 461 943 1 2
GDNF NEUROG2 0 0 504 523 1 1
GDNF EPHA4 0 0 261 288 1 1
GDNF CNTNAP1 0 0 103 152 1 1
GDNF AGER 0 0 156 155 1 2
GDNF NEFL 0 0 321 321 1 1
GDNF PRPH2 0 0 166 351 1 1
GDNF NEUROG3 0 0 391 392 1 1
GDNF HMGCS2 0 0 0 187 1 1
GDNF CRYGC 0 0 155 154 1 1
GDNF CUX1 0 0 309 309 1 1
GDNF ACVR2B 0 0 81 179 1 1
GDNF IL1A 0 0 280 280 1 1
GDNF AQP2 0 0 207 207 1 1
GDNF KIF20A 270 0 0 270 1 1
GDNF HTR1A 0 0 232 231 1 1
GDNF CCL4 0 0 171 171 1 1
GDNF PAX6 0 0 509 527 1 1
GDNF WNT1 0 0 391 390 1 2
GDNF ABCA1 0 0 89 151 1 2
GDNF BMP10 0 0 45 305 1 1
GDNF ALK 0 0 167 167 1 2
GDNF BCHE 0 0 236 236 1 1
GDNF DRD2 0 0 367 368 1 1
GDNF MYOC 0 0 95 185 1 1
GDNF NODAL 0 0 181 181 1 1
GDNF GFRA2 486 500 864 985 1 1
GDNF LGALS4 0 0 167 167 1 1
GDNF CTGF 0 0 157 194 1 1
GDNF P2RX7 0 0 217 217 1 2
GDNF HES5 0 0 215 215 1 1
GDNF OMG 0 0 298 298 1 1
GDNF PDGFA 0 0 261 261 1 1
GDNF CORIN 0 0 170 169 1 1
GDNF NR3C1 0 0 243 242 1 1
GDNF GZF1 0 0 250 301 1 1
GDNF CCDC6 0 0 214 269 1 1
GDNF CLDN11 0 0 265 265 1 1
GDNF VR1 0 0 603 620 1 1
GDNF GRM3 0 0 193 193 1 1
GDNF PXN 0 900 73 903 1 1
GDNF HIST2H3PS2 0 0 293 293 1 1
GDNF TRPM8 0 0 360 360 1 1
GDNF FGF18 0 0 152 274 1 1
GDNF FOXP1 0 0 213 213 1 1
GDNF CALCA 0 0 561 570 1 1
GDNF MUT 0 0 102 168 1 1
GDNF PSPN 0 500 804 592 1 1
GDNF ENO2 0 0 395 399 1 1
GDNF NANOS3 0 0 370 370 1 1
GDNF PTK2 0 900 240 920 1 2
GDNF GRB7 0 900 55 901 1 1
GDNF MAPK8 0 900 235 920 1 2
GDNF ARG1 0 0 260 260 1 2
GDNF VIM 0 0 211 228 1 2
GDNF IGFBP1 0 0 261 267 1 1
GDNF IL17A 0 0 234 234 1 2
GDNF PTPRS 0 0 203 203 1 1
GDNF HNF1A 0 0 150 162 1 1
GDNF EGF 0 0 667 677 1 2
GDNF RGMA 0 0 150 190 1 1
GDNF BMP2 0 0 414 426 1 1
GDNF SLIT1 0 0 234 261 1 1
GDNF CASP9 0 0 260 260 1 2
GDNF VCAN 0 0 422 435 1 1
GDNF NANOG 0 0 466 469 1 2
GDNF SLC1A2 0 0 470 471 1 1
GDNF UBE3D 0 0 74 235 1 1
GDNF ITGA8 0 0 261 261 1 1
GDNF POMC 0 0 261 261 1 1
GDNF GDF2 0 0 123 177 1 1
GDNF ALDH1L1 0 0 184 183 1 1
GDNF NRP1 0 0 217 230 1 1
GDNF CYCS 0 0 364 364 1 2
GDNF OGG1 0 0 0 209 1 1
GDNF CHAT 0 0 602 602 1 1
GDNF MYCL 0 0 194 194 1 1
GDNF NGB 0 0 161 161 1 1
GDNF HSPB3 0 0 181 181 1 1
GDNF NES 0 0 654 664 1 2
GDNF PDE6B 0 0 180 185 1 1
GDNF LHX8 0 0 150 162 1 1
GDNF CCR2 0 0 210 210 1 2
GDNF PPARA 0 0 170 169 1 2
GDNF SRGAP1 0 0 63 191 1 1
GDNF TEK 0 0 244 243 1 1
GDNF ACHE 0 0 391 390 1 2
GDNF ACVR1 0 0 108 199 1 1
GDNF HSPA4 0 0 320 319 1 1
GDNF GATA4 0 0 268 268 1 2
GDNF LIF 0 0 605 623 1 2
GDNF ETV5 0 0 558 558 1 1
GDNF CX3CR1 0 0 254 254 1 1
GDNF PIK3R1 0 900 66 902 1 1
GDNF DICER1 0 0 193 193 1 1
GDNF SDHC 0 0 292 292 1 1
GDNF IGF1R 0 0 247 246 1 2
GDNF PI3 0 0 193 193 1 2
GDNF TPH1 0 0 246 245 1 1
GDNF SLC18A2 0 0 506 518 1 1
GDNF FGF10 0 0 532 550 1 1
GDNF PPARGC1A 0 0 227 226 1 2
GDNF SLC1A3 0 0 470 479 1 1
GDNF IL15 0 0 166 165 1 1
GDNF MYC 0 0 405 405 1 2
GDNF FABP7 0 0 268 268 1 1
GDNF WNT5A 0 0 324 337 1 2
GDNF IL18 0 0 181 181 1 2
GDNF SLC6A4 0 0 283 282 1 1
GDNF TMEFF2 0 0 112 186 1 1
GDNF PARK2 0 0 392 392 1 1
GDNF NDUFS6 336 0 0 336 1 1
GDNF SOX11 0 0 193 193 1 1
GDNF LMO3 0 0 108 224 1 1
GDNF PAX7 0 0 277 277 1 1
GDNF NCAN 0 0 243 242 1 1
GDNF PIK3CA 0 900 83 904 1 2
GDNF TMEM127 0 0 389 388 1 1
GDNF RARG 0 0 113 164 1 1
GDNF GAB2 0 600 47 605 1 1
GDNF GFRAL 0 0 706 725 1 1
GDNF NOG 0 0 518 537 1 1
GDNF MAP2 0 0 558 558 1 2
GDNF OSR1 0 0 206 239 1 1
GDNF ADORA1 0 0 258 258 1 1
GDNF PIK3R3 0 600 0 600 1 1
GDNF HS6ST1 0 0 134 150 1 1
GDNF SEMA6A 0 0 325 325 1 1
GDNF GNAQ 0 0 147 179 1 1
GDNF SCN2A 0 0 155 154 1 1
GDNF NTS 417 0 263 572 1 1
GDNF SEMA4C 0 0 341 341 1 1
GDNF PARK7 0 0 395 403 1 2
GDNF EFNA5 0 0 251 250 1 1
GDNF SYNPO 0 0 161 179 1 1
GDNF LRIG3 0 0 141 201 1 1
GDNF ACRC 0 0 195 279 1 1
GDNF C9orf72 0 0 325 325 1 2
GDNF DLX2 0 0 270 285 1 1
GDNF MYCN 0 0 244 243 1 1
GDNF SMAD4 0 0 180 196 1 2
GDNF INHBA 0 0 163 267 1 1
GDNF ACPP 0 0 122 176 1 1
GDNF NPY 0 0 409 412 1 1
GDNF AREG 0 0 242 258 1 1
GDNF FURIN 0 0 184 183 1 1
GDNF PDGFB 0 0 184 183 1 2
GDNF OPA1 0 0 120 180 1 2
GDNF B4GALNT1 0 0 154 160 1 1
GDNF MAP2K1 0 0 324 323 1 1
GDNF FUT4 0 0 205 205 1 1
GDNF BTC 0 0 112 176 1 1
GDNF OSM 0 0 167 167 1 1
GDNF AQP1 0 0 233 260 1 1
GDNF MECP2 0 0 225 224 1 1
GDNF NFE2L2 0 0 203 208 1 2
GDNF NKX6-1 0 0 268 268 1 1
GDNF SPRY3 0 0 157 187 1 1
GDNF MNX1 0 0 257 331 1 1
GDNF FRS2 0 900 324 929 1 1
GDNF PPP1R1B 0 0 369 369 1 1
GDNF LHX1 0 0 578 578 1 1
GDNF AMHR2 0 0 141 194 1 1
GDNF SLC2A1 0 0 217 217 1 2
GDNF HOXB4 0 0 218 218 1 1
GDNF FGFR3 0 0 219 244 1 1
GDNF ADORA3 0 0 214 214 1 1
GDNF HTT 0 0 409 412 1 2
GDNF MYD88 0 0 161 161 1 2
GDNF EGFR 0 0 379 392 1 2
GDNF DHH 0 0 244 257 1 1
GDNF LRIG1 0 0 217 250 1 1
GDNF CTNNA1 0 900 47 900 1 1
GDNF PCDH13 0 0 0 167 1 1
GDNF MAOA 0 0 268 270 1 1
GDNF SLC12A5 0 0 193 193 1 1
GDNF TP53 0 0 392 392 1 2
GDNF SATB2 0 0 195 195 1 1
GDNF SCN10A 0 0 455 455 1 1
GDNF HMGCS1 0 0 397 397 1 1
GDNF RGS5 0 0 84 176 1 1
GDNF ZNF256 0 0 190 190 1 1
GDNF DAZL 0 0 469 478 1 1
GDNF WNT4 0 0 458 468 1 1
GDNF HOXB5 0 0 180 179 1 1
GDNF EMX1 0 0 209 215 1 1
GDNF HDAC2 0 0 445 445 1 1
GDNF CD200R1 0 0 181 181 1 1
GDNF LINGO1 0 0 262 295 1 1
GDNF PAEP 0 0 167 168 1 1
GDNF PABPC1 0 0 45 236 1 1
GDNF PRKACG 0 900 0 901 1 1
GDNF HOXC9 0 0 218 218 1 1
GDNF PLP1 0 0 232 231 1 1
GDNF RAF1 0 0 172 171 1 2
GDNF PITX2 0 0 214 232 1 1
GDNF LMX1B 0 0 363 367 1 1
GDNF CSF3 0 0 391 391 1 1
GDNF P2RX4 0 0 205 205 1 1
GDNF NTSR1 0 0 212 212 1 1
GDNF EDN3 0 0 631 634 1 1
GDNF OCM 0 0 181 188 1 1
GDNF LRIG2 0 0 195 222 1 1
GDNF TLX1 0 0 391 448 1 1
GDNF FGF7 0 0 456 523 1 1
GDNF CLU 0 0 210 210 1 2
GDNF SEMA3D 0 0 368 368 1 1
GDNF VGF 0 0 284 284 1 1
GDNF TEX14 0 0 140 161 1 1
GDNF NR4A1 0 0 206 206 1 2
GDNF GHRL 0 0 153 152 1 1
GDNF SEMA3C 0 0 364 377 1 1
GDNF JAK2 0 0 193 193 1 2
GDNF NGFRAP1 0 0 149 172 1 1
GDNF EMX2 0 0 307 322 1 1
GDNF SHC3 0 500 142 552 1 1
GDNF CDH2 0 0 490 490 1 1
GDNF PTX3 0 0 123 160 1 1
GDNF SEMA3B 0 0 360 376 1 1
GDNF AGO2 270 0 52 278 1 2
GDNF TGFA 0 0 211 211 1 1
GDNF PTN 0 0 466 480 1 1
GDNF HOXC5 0 0 135 173 1 1
GDNF ARMC8 457 0 0 457 1 1
GDNF HBEGF 0 0 323 337 1 1
GDNF PPP1R12C 0 0 180 179 1 1
GDNF STAT3 0 0 391 390 1 2
GDNF CLCN5 0 0 71 215 1 1
GDNF GAS1 0 0 337 419 1 1
GDNF PCSK5 0 0 153 152 1 1
GDNF RMND5A 496 0 0 495 1 1
GDNF FREM2 0 0 211 219 1 1
GDNF GSX2 0 0 241 240 1 1
GDNF DYNLL1 0 0 57 158 1 1
GDNF GATA3 0 0 262 276 1 1
GDNF CXCL8 0 0 369 369 1 2
GDNF DOK7 0 0 92 190 1 1
GDNF GBX2 0 0 185 185 1 1
GDNF SULF2 0 0 371 376 1 1
GDNF PAX2 0 0 716 721 1 1
GDNF SLC1A7 0 0 164 163 1 1
GDNF WNT7A 0 0 238 237 1 1
GDNF EDN1 0 0 283 282 1 1
GDNF HIF1A 0 0 323 323 1 2
GDNF FZD4 0 0 113 249 1 1
GDNF YPEL5 447 0 0 447 1 1
GDNF EN2 0 0 137 169 1 1
GDNF WNT7B 0 0 294 294 1 1
GDNF ISL1 0 0 497 501 1 1
GDNF IL1B 0 0 560 560 1 2
GDNF BMP15 0 0 112 264 1 1
GDNF NKX6-2 0 0 243 242 1 1
GDNF SP1 0 0 150 211 1 2
GDNF WNT2B 0 0 201 258 1 1
GDNF HOXA11 0 0 218 235 1 1
GDNF RHO 0 0 310 309 1 2
GDNF ARC 0 0 161 161 1 2
GDNF ASPA 0 0 122 156 1 1
GDNF HRAS 0 900 211 923 1 2
GDNF CTNNB1 0 900 427 940 1 2
GDNF TRPV1 0 0 603 620 1 2
GDNF SCN1A 0 0 234 234 1 1
GDNF EGR1 0 0 324 323 1 2
GDNF APP 0 0 459 470 1 2
GDNF TBR1 0 0 286 286 1 1
GDNF MTOR 0 0 302 302 1 2
GDNF BMP3 0 0 124 217 1 1
GDNF SMO 0 0 0 206 1 1
GDNF SORT1 0 0 266 266 1 1
GDNF FAM162B 0 0 203 203 1 1
GDNF POTEF 0 0 241 298 1 1
GDNF DCTN2 0 0 292 292 1 1
GDNF PTPRU 0 0 157 172 1 1
GDNF CXCR4 0 0 392 400 1 2
GDNF FGF13 0 0 654 659 1 1
GDNF PSEN2 0 0 180 179 1 1
GDNF NRP2 0 0 288 293 1 1
GDNF L1CAM 0 0 283 295 1 1
GDNF MMP1 0 0 127 181 1 1
GDNF NOTCH1 0 0 413 417 1 2
GDNF UNC5C 0 0 134 247 1 1
GDNF ELAVL3 0 0 266 266 1 1
GDNF HGFAC 0 0 161 161 1 1
GDNF STAT1 0 0 205 205 1 2
GDNF OCLN 0 0 325 325 1 1
GDNF MYOG 0 0 181 181 1 1
GDNF NPHS1 0 0 229 228 1 1
GDNF TNFRSF1A 0 0 288 288 1 1
GDNF RPS6 0 0 139 178 1 2
GDNF SMN1 0 0 213 213 1 1
GDNF CHMP2B 0 0 112 258 1 2
GDNF MPO 0 0 175 175 1 2
GDNF DOK2 0 600 60 607 1 1
GDNF MPZ 0 0 379 379 1 1
GDNF IL6 0 0 558 569 1 2
GDNF MOG 0 0 202 202 1 1
GDNF CTRL 0 0 154 153 1 2
GDNF GAST 0 0 151 150 1 1
GDNF RAPGEF3 0 0 154 153 1 1
GDNF IFNG 0 0 293 293 1 2
GDNF CREB1 0 900 737 972 1 2
GDNF TGFB3 0 0 506 517 1 1
GDNF CCL5 0 0 292 292 1 2
GDNF SDF4 0 0 218 218 1 1
GDNF FGF14 0 0 49 262 1 1
GDNF EFNB1 0 0 184 201 1 1
GDNF TMEM119 0 0 93 180 1 1
GDNF PRKACA 0 900 0 901 1 1
GDNF CALB2 0 0 341 341 1 1
GDNF FRAS1 0 0 256 287 1 1
GDNF BCL11B 0 0 241 240 1 1
GDNF CDNF 0 0 681 687 1 1
GDNF SDHB 0 0 358 358 1 1
GDNF GRB10 0 900 61 904 1 1
GDNF CCL13 0 0 156 155 1 1
GDNF PIEZO2 0 0 219 219 1 1
GDNF CREBBP 0 0 195 195 1 1
GDNF POU3F2 0 0 358 358 1 1
GDNF GDF9 0 0 189 207 1 1
GDNF POU3F3 0 0 191 208 1 1
GDNF SIRT2 0 0 195 195 1 2
GDNF RGS4 0 0 137 264 1 1
GDNF NCS1 0 0 328 328 1 1
GDNF METRN 0 0 155 193 1 1
GDNF CXCL13 0 0 143 161 1 1
GDNF EPO 0 0 469 496 1 2
GDNF ATF5 0 0 233 232 1 1
GDNF RELN 0 0 299 299 1 1
GDNF NAV1 0 0 181 181 1 1
GDNF WNT11 0 0 691 706 1 1
GDNF IL1RAPL1 0 0 306 306 1 1
GDNF MYT1L 0 0 279 295 1 1
GDNF FGF21 0 0 95 466 1 2
GDNF GRIA2 0 0 233 232 1 1
GDNF DMRT3 0 0 108 162 1 1
GDNF WNT8A 0 0 155 154 1 1
GDNF ANXA5 0 0 209 209 1 2
GDNF CTNND1 0 900 72 903 1 1
GDNF AKAP12 0 0 161 161 1 1
GDNF NRG2 0 0 168 167 1 1
GDNF PCDH20 0 0 0 167 1 1
GDNF DNMT3B 0 0 175 175 1 1
GDNF SLC16A12 0 0 163 163 1 1
GDNF DNMT3A 0 0 160 159 1 2
GDNF RORA 0 0 171 193 1 1
GDNF BCL2L1 0 0 325 325 1 2
GDNF GJB6 0 0 161 161 1 1
GDNF ETAA1 209 0 0 209 1 1
GDNF CHRNA4 0 0 108 177 1 1
GDNF SOX3 0 0 263 336 1 1
GDNF ALDH1A2 0 0 234 234 1 1
GDNF KITLG 0 0 469 490 1 1
GDNF CASP6 0 0 148 166 1 1
GDNF ADCYAP1 0 0 265 265 1 1
GDNF RAP1A 0 900 0 900 1 1
GDNF SLC18A3 0 0 335 335 1 1
GDNF NEFM 0 0 283 282 1 1
GDNF UTF1 0 0 263 263 1 1
GDNF MAP2K7 0 0 392 392 1 1
GDNF NOS2 0 0 181 181 1 2
GDNF CX3CL1 0 0 375 375 1 1
GDNF NF1 0 0 295 295 1 1
GDNF PROK1 0 0 294 312 1 1
GDNF FGFR2 0 0 335 356 1 1
GDNF KCNC1 0 0 296 296 1 1
GDNF HTR3A 0 0 181 181 1 1
GDNF SMAD2 0 0 194 216 1 2
GDNF PABPC3 0 0 0 232 1 1
GDNF TLR4 0 0 297 297 1 2
GDNF GREM1 0 0 342 371 1 1
GDNF CCDC152 0 0 91 153 1 1
GDNF GAPDH 0 0 528 528 1 2
GDNF SIX2 0 0 619 650 1 1
GDNF EGR3 0 0 206 206 1 1
GDNF NDNF 0 0 63 223 1 1
GDNF OLIG1 0 0 323 323 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:1902379 Molecular Function chemoattractant activity involved in axon guidance enables TAS
GO:0030116 Molecular Function glial cell-derived neurotrophic factor receptor binding enables IEA
GO:0008083 Molecular Function growth factor activity enables IBA
GO:0005515 Molecular Function protein binding enables IPI
GO:0042803 Molecular Function protein homodimerization activity enables IDA
GO:0030971 Molecular Function receptor tyrosine kinase binding enables IEA
GO:0005102 Molecular Function signaling receptor binding enables TAS
GO:0008344 Biological Process adult locomotory behavior involved_in TAS
GO:0001658 Biological Process branching involved in ureteric bud morphogenesis involved_in ISS
GO:0061642 Biological Process chemoattraction of axon involved_in IEA
GO:0071679 Biological Process commissural neuron axon guidance involved_in ISS
GO:0021516 Biological Process dorsal spinal cord development involved_in ISS
GO:0048568 Biological Process embryonic organ development involved_in ISS
GO:0048484 Biological Process enteric nervous system development involved_in ISS
GO:0048255 Biological Process mRNA stabilization involved_in IDA
GO:0003337 Biological Process mesenchymal to epithelial transition involved in metanephros morphogenesis involved_in IEA
GO:0001656 Biological Process metanephros development involved_in ISS
GO:0043066 Biological Process negative regulation of apoptotic process involved_in TAS
GO:2001240 Biological Process negative regulation of extrinsic apoptotic signaling pathway in absence of ligand involved_in IDA
GO:0043524 Biological Process negative regulation of neuron apoptotic process involved_in IBA
GO:0043524 Biological Process negative regulation of neuron apoptotic process involved_in IDA
GO:0007399 Biological Process nervous system development involved_in TAS
GO:0001755 Biological Process neural crest cell migration acts_upstream_of_or_within IDA
GO:0031175 Biological Process neuron projection development acts_upstream_of_or_within IDA
GO:0031175 Biological Process neuron projection development involved_in TAS
GO:0001759 Biological Process organ induction involved_in IEA
GO:0007422 Biological Process peripheral nervous system development involved_in IBA
GO:0030432 Biological Process peristalsis involved_in ISS
GO:0090190 Biological Process positive regulation of branching involved in ureteric bud morphogenesis involved_in IBA
GO:0090190 Biological Process positive regulation of branching involved in ureteric bud morphogenesis involved_in IDA
GO:0045597 Biological Process positive regulation of cell differentiation acts_upstream_of_or_within IGI
GO:0008284 Biological Process positive regulation of cell population proliferation acts_upstream_of_or_within IDA
GO:0033603 Biological Process positive regulation of dopamine secretion involved_in TAS
GO:0072108 Biological Process positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis involved_in IEA
GO:0032770 Biological Process positive regulation of monooxygenase activity involved_in IDA
GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II involved_in IDA
GO:0072107 Biological Process positive regulation of ureteric bud formation involved_in IDA
GO:0021784 Biological Process postganglionic parasympathetic fiber development involved_in ISS
GO:0001941 Biological Process postsynaptic membrane organization involved_in IEA
GO:0051584 Biological Process regulation of dopamine uptake involved in synaptic transmission involved_in IDA
GO:0010468 Biological Process regulation of gene expression acts_upstream_of_or_within IGI
GO:0060688 Biological Process regulation of morphogenesis of a branching structure involved_in ISS
GO:2001260 Biological Process regulation of semaphorin-plexin signaling pathway involved_in ISS
GO:2000736 Biological Process regulation of stem cell differentiation involved_in TAS
GO:0007165 Biological Process signal transduction involved_in TAS
GO:0048485 Biological Process sympathetic nervous system development involved_in ISS
GO:0060676 Biological Process ureteric bud formation involved_in IEA
GO:0005794 Cellular Component Golgi apparatus located_in IDA
GO:0005576 Cellular Component extracellular region located_in IDA
GO:0005576 Cellular Component extracellular region located_in TAS
GO:0005615 Cellular Component extracellular space is_active_in IBA
Pathways
Name DB ID
Developmental Biology Reactome R-HSA-1266738
Signal Transduction Reactome R-HSA-162582
NCAM signaling for neurite out-growth Reactome R-HSA-375165
NCAM1 interactions Reactome R-HSA-419037
Axon guidance Reactome R-HSA-422475
RAF/MAP kinase cascade Reactome R-HSA-5673001
MAPK family signaling cascades Reactome R-HSA-5683057
MAPK1/MAPK3 signaling Reactome R-HSA-5684996
RET signaling Reactome R-HSA-8853659
Nervous system development Reactome R-HSA-9675108
Development of ureteric collection system (WP5053) WikiPathways WP5053_r118778
Genes controlling nephrogenesis (WP4823) WikiPathways WP4823_r119116
Allograft rejection (WP2328) WikiPathways WP2328_r120805
Markers of kidney cell lineage (WP5236) WikiPathways WP5236_r124473
Spinal cord injury (WP2431) WikiPathways WP2431_r120812
GDNF/RET signaling axis (WP4830) WikiPathways WP4830_r118773
Transcripts
Accession Version MolecularType Name NCBI Comments
XM_017009337 3 mRNA transcript variant X1 NC_000005 Reference
NM_000514 4 mRNA transcript variant 1 NC_000005 Reference
NM_001190469 1 mRNA transcript variant 4 NC_000005 Reference
NM_001190468 1 mRNA transcript variant 3 NC_000005 Reference
NM_199231 2 mRNA transcript variant 2 NC_000005 Reference
NM_001278098 1 mRNA transcript variant 6 NC_000005 Reference