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TMEM150B

transmembrane protein 150B
General Information
Name transmembrane protein 150B
Alias
  • modulator of macroautophagy TMEM150B
  • DRAM-Related/Associated Member 3
  • hCG1651476
  • protein DRAM-3
  • tentonin 2
  • transmembrane protein 224
  • transmembrane protein LOC284417
Gene_family
organism Homo sapiens
entrez_id 284417
location 19q13.42
transcript_count 18
exon_count 12
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez This gene encodes a protein that belongs to the DRAM (damage-regulated autophagy modulator) family of membrane-spanning proteins. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
    Stringdb Modulator of macroautophagy TMEM150B; Modulator of macroautophagy that causes accumulation of autophagosomes under basal conditions and enhances autophagic flux. Represses cell death and promotes long-term clonogenic survival of cells grown in the absence of glucose in a macroautophagy-independent manner. May have some role in extracellular matrix engulfment or growth factor receptor recycling, both of which can modulate cell survival; Belongs to the DRAM/TMEM150 family
    nextProt Modulator of macroautophagy that causes accumulation of autophagosomes under basal conditions and enhances autophagic flux (PubMed:25929859). Represses cell death and promotes long-term clonogenic survival of cells grown in the absence of glucose in a macroautophagy-independent manner (PubMed:25929859). May have some role in extracellular matrix engulfment or growth factor receptor recycling, both of which can modulate cell survival (PubMed:25929859).
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
StringDB
Ontologies
ID Category Term Effect Evidence PubMed
GO:0006914 Biological Process autophagy involved_in IEA
GO:0000421 Cellular Component autophagosome membrane located_in IEA
GO:0010008 Cellular Component endosome membrane located_in IEA
GO:0005886 Cellular Component plasma membrane located_in IDA
Pathways
Name DB ID
Transcripts