H2AX

H2A.X variant histone

General Information

Name	H2A.X variant histone
Alias	histone H2AX H2A histone family member X H2AX histone histone H2A.x
Gene_family	H2A histones
organism	Homo sapiens
entrez_id	3014
location	11q23.3
transcript_count	1
exon_count	1

Cross References

Location

by NCBI GRCh38.p14

Summary

Entrez Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015]

nextProt Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.

Interactions

NCBI

A	A.Source	B	B.DB	B.Source	Description
H2AX	BioGRID	BRCA1	GeneID	BioGRID	Affinity Capture-Western; Biochemical Activity; Co-localization; Reconstituted Complex
H2AX	BioGRID	N	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	MDC1	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Co-localization; Protein-peptide; Reconstituted Complex
H2AX	BioGRID	METTL14	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ATM	GeneID	BioGRID	Affinity Capture-Western; Biochemical Activity; Co-localization
H2AX	BioGRID	VCP	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	PIAS1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	SNCA	GeneID	BioGRID	Affinity Capture-MS; Proximity Label-MS
H2AX	BioGRID	USP48	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	STAU1	GeneID	BioGRID	Proximity Label-MS
H2AX	BioGRID	PHGDH	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	TRIM67	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	Cavin3	GeneID	BioGRID	Affinity Capture-Western
H2AX	BioGRID	ZRANB1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	CAVIN3	GeneID	BioGRID	Co-localization
H2AX	BioGRID	ACE2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	PPP1CA	GeneID	BioGRID	Affinity Capture-Western; Co-localization
H2AX	BioGRID	USP49	GeneID	BioGRID	Affinity Capture-Western
H2AX	BioGRID	PABPC1	GeneID	BioGRID	Affinity Capture-MS; Co-fractionation
H2AX	BioGRID	HNRNPUL2	GeneID	BioGRID	Co-fractionation
H2AX	BioGRID	HNRNPR	GeneID	BioGRID	Affinity Capture-MS; Co-fractionation
H2AX	BioGRID	HSPA5	GeneID	BioGRID	Affinity Capture-MS; Co-fractionation
H2AX	BioGRID	DHX9	GeneID	BioGRID	Affinity Capture-Western; Co-fractionation; Reconstituted Complex
H2AX	BioGRID	CALR	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Co-fractionation
H2AX	BioGRID	PARP1	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Co-localization; Reconstituted Complex
H2AX	BioGRID	XRCC6	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Reconstituted Complex
H2AX	BioGRID	SUPT16H	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Reconstituted Complex
H2AX	BioGRID	YBX3	GeneID	BioGRID	Affinity Capture-MS; Co-fractionation
H2AX	BioGRID	H4C1	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Proximity Label-MS
H2AX	BioGRID	H2BC14	GeneID	BioGRID	Affinity Capture-MS; Co-fractionation; Proximity Label-MS
H2AX	BioGRID	TP53BP1	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Co-localization; Protein-peptide
H2AX	BioGRID	SSRP1	GeneID	BioGRID	Affinity Capture-MS; Co-fractionation; Reconstituted Complex
H2AX	BioGRID	SSB	GeneID	BioGRID	Affinity Capture-MS; Co-fractionation
H2AX	BioGRID	PTCD3	GeneID	BioGRID	Affinity Capture-MS; Co-fractionation
H2AX	BioGRID	CC2D1A	GeneID	BioGRID	Co-fractionation
H2AX	BioGRID	EIF3L	GeneID	BioGRID	Affinity Capture-MS; Co-fractionation
H2AX	BioGRID	NPM1	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Co-fractionation
H2AX	BioGRID	RNF43	GeneID	BioGRID	Affinity Capture-Western
H2AX	BioGRID	ERRFI1	GeneID	BioGRID	Affinity Capture-Western
H2AX	BioGRID	TOPORS	GeneID	BioGRID	Affinity Capture-Western; Biochemical Activity
H2AX	BioGRID	UBE2O	GeneID	BioGRID	Affinity Capture-Western
H2AX	BioGRID	ORF1ab	GeneID	BioGRID	Protein-RNA
H2AX	BioGRID	PPM1G	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western
H2AX	BioGRID	NUMA1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	GRB2	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
H2AX	BioGRID	H3C1	GeneID	BioGRID	Affinity Capture-Western; Co-fractionation; Co-localization
H2AX	BioGRID	HDGFL2	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western
H2AX	BioGRID	MAD2L2	GeneID	BioGRID	Affinity Capture-Western
H2AX	BioGRID	TPT1	GeneID	BioGRID	Affinity Capture-Western
H2AX	BioGRID	SMARCA4	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
H2AX	BioGRID	Srsf9	GeneID	BioGRID	Two-hybrid
H2AX	BioGRID	BIRC5	GeneID	BioGRID	Affinity Capture-Western
H2AX	BioGRID	CTBP1	GeneID	BioGRID	Two-hybrid
H2AX	BioGRID	MRPL35	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	SS18L2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RPL26L1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	YBX2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	MRPS7	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	MACROD1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ZBTB11	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	AGO1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RPL36	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ZNF346	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	KIFAP3	GeneID	BioGRID	Affinity Capture-Western; Co-localization
H2AX	BioGRID	KRR1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	NUP42	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	SF3B2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	UQCR11	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	B3GNT2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	CTCF	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	PAIP1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	AGPAT1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	NPM3	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	PARP2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RBM19	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ZBTB24	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	LZTS3	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	PHF14	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	CHD1L	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	MACROH2A1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	XRCC1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	XPC	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western
H2AX	BioGRID	TUB	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	SURF2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	SUPT6H	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	SNRPE	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	SNRPB2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	HLTF	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	SRSF6	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RPS28	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RPS27A	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RPS18	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RPS16	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RPS15	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RPS10	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RPS5	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RPS3A	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RPS3	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RPS2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RPLP0	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RPL37	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RPL26	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RPL8	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RPL7A	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RPL4	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RAN	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	YBX1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	NPAT	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	TONSL	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	NBN	GeneID	BioGRID	Affinity Capture-Western; Co-localization; Reconstituted Complex
H2AX	BioGRID	NAP1L1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	MCM7	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	MCM6	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	MCM5	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	MCM4	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	MCM2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	MBNL1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	MAGEB2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	LIG3	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ILF2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	HMGA1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	HMGN1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	H2BC5	GeneID	BioGRID	Affinity Capture-MS; Proximity Label-MS
H2AX	BioGRID	H1-6	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	H1-2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	IFI6	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	FGF8	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	FGF3	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	CKMT2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	CETN2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	CETN1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	CAPZA2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	NEIL1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	CCDC86	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	KRI1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	GINS3	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ELOVL5	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	MIER1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	NHSL3	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	CRAMP1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	REXO4	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ZC3HAV1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	BEX1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	IPO9	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	THUMPD1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	LARP1B	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	DYNC2I1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ANKHD1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	GON4L	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	GINS2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	LARP7	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RRP9	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	SART1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	H2AC11	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	TIMELESS	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	PRKRA	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	H4C14	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	H4C13	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	H4C2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	H2BC17	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	H2BC10	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	H2AC20	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western
H2AX	BioGRID	GAN	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	H3-7	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	PAIP2B	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	C16orf87	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	NPSR1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	C1orf174	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	H2AC21	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	C5orf64	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	TSSK4	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	MMS22L	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	MIER3	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ZNF420	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	MAGEB10	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	PABPC4L	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ZNF653	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ZNF689	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ZFAND2A	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ZMAT1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	LLPH	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	GINS4	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	C18orf21	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ZNF668	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	LIN28A	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ADARB1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	WDR5	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	FZR1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	NEDD4L	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	PDIA4	GeneID	BioGRID	Affinity Capture-MS; Proximity Label-MS
H2AX	BioGRID	DDX23	GeneID	BioGRID	Proximity Label-MS
H2AX	BioGRID	BAZ1B	GeneID	BioGRID	Affinity Capture-Western; Biochemical Activity
H2AX	BioGRID	LAMP1	GeneID	BioGRID	Proximity Label-MS
H2AX	BioGRID	COX4I1	GeneID	BioGRID	Proximity Label-MS
H2AX	BioGRID	CENPA	GeneID	BioGRID	Affinity Capture-MS; Proximity Label-MS
H2AX	BioGRID	H2BC8	GeneID	BioGRID	Proximity Label-MS
H2AX	BioGRID	H2BC11	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	HIRIP3	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	H4C9	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ACACA	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RING1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RBBP8	GeneID	BioGRID	Co-localization
H2AX	BioGRID	PTEN	GeneID	BioGRID	Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
H2AX	BioGRID	MRE11	GeneID	BioGRID	Affinity Capture-Western; Co-localization
H2AX	BioGRID	H3-3A	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western
H2AX	BioGRID	RNF168	GeneID	BioGRID	Affinity Capture-Western; Biochemical Activity; Co-localization
H2AX	BioGRID	H3C14	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western
H2AX	BioGRID	ZNF514	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	PCGF1	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Co-localization
H2AX	BioGRID	KDM2B	GeneID	BioGRID	Affinity Capture-MS; Co-localization
H2AX	BioGRID	RIN3	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	BCOR	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	UIMC1	GeneID	BioGRID	Co-localization
H2AX	BioGRID	SND1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	SCMH1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	HMG20A	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	YAF2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RAD50	GeneID	BioGRID	Affinity Capture-Western; Co-localization
H2AX	BioGRID	MYSM1	GeneID	BioGRID	Affinity Capture-Western; Co-localization
H2AX	BioGRID	PALB2	GeneID	BioGRID	Co-localization
H2AX	BioGRID	NUPR1	GeneID	BioGRID	Co-localization
H2AX	BioGRID	CIT	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	BRD3	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	NEK4	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	MNDA	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	MKI67	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	IFI16	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ANLN	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	PYHIN1	GeneID	BioGRID	Co-localization
H2AX	BioGRID	CHMP4C	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	KIF20A	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	KIF14	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	BCAR1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	KIF23	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	PRC1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	LOC102724334	GeneID	BioGRID	Proximity Label-MS
H2AX	BioGRID	H2BC18	GeneID	BioGRID	Proximity Label-MS
H2AX	BioGRID	H2BC20P	GeneID	BioGRID	Proximity Label-MS
H2AX	BioGRID	GPATCH8	GeneID	BioGRID	Proximity Label-MS
H2AX	BioGRID	PRKCB	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	H2BC21	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Proximity Label-MS
H2AX	BioGRID	H2BC9	GeneID	BioGRID	Proximity Label-MS
H2AX	BioGRID	H3-4	GeneID	BioGRID	Proximity Label-MS
H2AX	BioGRID	ZC3H18	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	MTA2	GeneID	BioGRID	Affinity Capture-MS; Co-localization
H2AX	BioGRID	USP11	GeneID	BioGRID	Affinity Capture-Western; Biochemical Activity; Co-localization; Reconstituted Complex
H2AX	BioGRID	HDAC2	GeneID	BioGRID	Affinity Capture-MS; Co-localization
H2AX	BioGRID	ZBTB14	GeneID	BioGRID	Co-localization
H2AX	BioGRID	SMURF2	GeneID	BioGRID	Affinity Capture-Western
H2AX	BioGRID	MORC2	GeneID	BioGRID	Co-localization
H2AX	BioGRID	POLR2A	GeneID	BioGRID	Affinity Capture-Western; Co-localization
H2AX	BioGRID	HNRNPD	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	FANCD2	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western
H2AX	BioGRID	TRAIP	GeneID	BioGRID	Co-localization
H2AX	BioGRID	RAD51	GeneID	BioGRID	Affinity Capture-Western; Co-localization
H2AX	BioGRID	PML	GeneID	BioGRID	Affinity Capture-Western; Co-localization
H2AX	BioGRID	EP300	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	SCML2	GeneID	BioGRID	Co-localization
H2AX	BioGRID	USP7	GeneID	BioGRID	Affinity Capture-MS; Co-localization
H2AX	BioGRID	DYRK1A	GeneID	BioGRID	Co-localization
H2AX	BioGRID	PELI1	GeneID	BioGRID	Affinity Capture-Western
H2AX	BioGRID	RPL6	GeneID	BioGRID	Affinity Capture-Western
H2AX	BioGRID	MSH6	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western
H2AX	BioGRID	MSH2	GeneID	BioGRID	Affinity Capture-Western
H2AX	BioGRID	MLH1	GeneID	BioGRID	Affinity Capture-Western
H2AX	BioGRID	PRKDC	GeneID	BioGRID	Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
H2AX	BioGRID	TRIM29	GeneID	BioGRID	Affinity Capture-Western
H2AX	BioGRID	KAT5	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
H2AX	BioGRID	SMC3	GeneID	BioGRID	Affinity Capture-Western
H2AX	BioGRID	USP14	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	SMC1A	GeneID	BioGRID	Affinity Capture-Western
H2AX	BioGRID	NR2C2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RNASEH2A	GeneID	BioGRID	Co-localization
H2AX	BioGRID	MAP1LC3A	GeneID	BioGRID	Affinity Capture-Western
H2AX	BioGRID	RNASEH2B	GeneID	BioGRID	Co-localization
H2AX	BioGRID	ULK1	GeneID	BioGRID	Affinity Capture-Western
H2AX	BioGRID	SMARCC2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	SMARCC1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	SMARCB1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	SMARCA1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	SET	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	BRD2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	DPF2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ARID4A	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RANGAP1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RANBP2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RAD23B	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RSF1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ARID4B	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	PHF21A	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	PHF20L1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	UHRF1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	HTATSF1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	PELP1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	CKAP2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	SIN3A	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	NIPBL	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ZMYND8	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ANP32CP	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	SUZ12	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ADNP	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	MDN1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RCOR1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	POGZ	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	KDM2A	GeneID	BioGRID	Affinity Capture-MS; Co-localization
H2AX	BioGRID	CBX3	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	BAZ2A	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	EHMT2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RUVBL2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	KANSL1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	CSNK2A3	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	WIZ	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	CHD8	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ZNF687	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	MTA3	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ARID1B	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	GATAD2B	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	WDR18	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	CTNNBL1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	CHAF1A	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RBX1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ZNF592	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	CDYL	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ZMYM3	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western
H2AX	BioGRID	MTA1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	MBD2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RUVBL1	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western
H2AX	BioGRID	SMARCA5	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ARID1A	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ANP32A	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ZMYM2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	HCFC1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	H3-3B	GeneID	BioGRID	Affinity Capture-Western
H2AX	BioGRID	GTF3C1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	BPTF	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	DNMT3B	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	DNMT3A	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	DDB1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	CSNK2A1	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Co-localization
H2AX	BioGRID	CHD4	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RCC1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	SAP130	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	UBB	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	SUPT5H	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	SMARCE1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	SMARCD2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	SMARCD1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	DMAP1	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western
H2AX	BioGRID	PBRM1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	GATAD2A	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	MBD3	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ATG16L1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	FH	GeneID	BioGRID	Co-localization
H2AX	BioGRID	H2AC4	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	H2BC3	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	BLM	GeneID	BioGRID	Affinity Capture-Western; Co-localization
H2AX	BioGRID	CDK9	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	DCPS	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RECQL4	GeneID	BioGRID	Co-localization
H2AX	BioGRID	UBE4A	GeneID	BioGRID	Co-localization
H2AX	BioGRID	TIFA	GeneID	BioGRID	Affinity Capture-Western
H2AX	BioGRID	MEPCE	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	HEXIM1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	H2AZ1	GeneID	BioGRID	Co-localization
H2AX	BioGRID	ESR2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	WRAP53	GeneID	BioGRID	Affinity Capture-Western; Co-localization
H2AX	BioGRID	BMI1	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Co-localization
H2AX	BioGRID	RNF2	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity
H2AX	BioGRID	H3C15	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ATRX	GeneID	BioGRID	Co-localization
H2AX	BioGRID	RNF8	GeneID	BioGRID	Biochemical Activity; Co-localization
H2AX	BioGRID	RNF115	GeneID	BioGRID	Affinity Capture-Western
H2AX	BioGRID	LMNA	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	FOXA1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	HIF1A	GeneID	BioGRID	Affinity Capture-Western; Co-localization
H2AX	BioGRID	UBC	GeneID	BioGRID	Affinity Capture-Western
H2AX	BioGRID	TRAF6	GeneID	BioGRID	Affinity Capture-Western; Biochemical Activity
H2AX	BioGRID	EGFR	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western
H2AX	BioGRID	ZCCHC9	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ZNF574	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	MRPS35	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ZNF22	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	CXXC1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ELAVL2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	DKC1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	CYP19A1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ZSCAN25	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RPS9	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RPS6	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RPL23A	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RPL19	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	UPF1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	EYA1	GeneID	BioGRID	Affinity Capture-Western; Biochemical Activity
H2AX	BioGRID	HUWE1	GeneID	BioGRID	Biochemical Activity
H2AX	BioGRID	BAZ1A	GeneID	BioGRID	Affinity Capture-Western
H2AX	BioGRID	BANP	GeneID	BioGRID	Affinity Capture-Western
H2AX	BioGRID	Srp72	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	DIS3L	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	MLLT1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	MCPH1	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
H2AX	BioGRID	ENY2	GeneID	BioGRID	Co-fractionation
H2AX	BioGRID	STK11	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	PAK1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	BARD1	GeneID	BioGRID	Reconstituted Complex
H2AX	BioGRID	USP17L2	GeneID	BioGRID	Affinity Capture-Western; Biochemical Activity
H2AX	BioGRID	DDX21	GeneID	BioGRID	Reconstituted Complex
H2AX	BioGRID	NCL	GeneID	BioGRID	Reconstituted Complex
H2AX	BioGRID	H3C2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ESR1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ATR	GeneID	BioGRID	Biochemical Activity; Co-localization
H2AX	BioGRID	CBX5	GeneID	BioGRID	Affinity Capture-Western
H2AX	BioGRID	TRIM28	GeneID	BioGRID	Affinity Capture-Western
H2AX	BioGRID	XRCC5	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western
H2AX	BioGRID	TERF2	GeneID	BioGRID	Two-hybrid
H2AX	BioGRID	SIRT7	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ARRB2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ARRB1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	PAXIP1	GeneID	BioGRID	Co-crystal Structure; Protein-peptide
H2AX	BioGRID	ATF2	GeneID	BioGRID	Affinity Capture-Western
H2AX	BioGRID	CBX2	GeneID	BioGRID	Co-localization
H2AX	BioGRID	QARS1	GeneID	BioGRID	Two-hybrid
H2AX	BioGRID	MASP1	GeneID	BioGRID	Two-hybrid
H2AX	BioGRID	NGFR	GeneID	BioGRID	Two-hybrid
H2AX	BioGRID	ACTB	GeneID	BioGRID	Two-hybrid
H2AX	BioGRID	A2M	GeneID	BioGRID	Two-hybrid
H2AX	BioGRID	OTUB1	GeneID	BioGRID	Two-hybrid
H2AX	BioGRID	TAF5L	GeneID	BioGRID	Two-hybrid
H2AX	BioGRID	TIAM2	GeneID	BioGRID	Two-hybrid
H2AX	BioGRID	COPG1	GeneID	BioGRID	Two-hybrid
H2AX	BioGRID	TAF1C	GeneID	BioGRID	Two-hybrid
H2AX	BioGRID	YWHAQ	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	PRDX6	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RAB11B	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	AIFM1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	P4HA2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	EIF2S2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	YWHAZ	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western
H2AX	BioGRID	YWHAE	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	YWHAB	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	HSP90B1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	TKT	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	STK4	GeneID	BioGRID	Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
H2AX	BioGRID	SSBP1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	SOD2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	S100A4	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RPN2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RPLP2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	PSMB4	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	PSMB3	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	PRKCSH	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	PPIA	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	PLOD1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	PKM	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	PGK1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	PCBP2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	P4HB	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	NONO	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western
H2AX	BioGRID	NACA	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	MSN	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	LGALS3BP	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	LDHB	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	HSP90AA1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	HSPA9	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	HSPA1L	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	HSPA1A	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	HNRNPH3	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	HNRNPC	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	HNRNPAB	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	HNRNPA2B1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	HNRNPA1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	HEXA	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	HSD17B10	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	GLB1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	PEF1	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western
H2AX	BioGRID	CMBL	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	NAXE	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	MSI2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	TMX1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	PTGES2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	P3H1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	FKBP10	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	VPS35	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ABHD10	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	RMDN1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	TXNDC12	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ERO1A	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	TOR1B	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	HIBCH	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	SUMF2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ENO1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ELAVL1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	EIF4A1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	EEF1B2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	TOR1A	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	CTSD	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	CPS1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	CLU	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	CFL1	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western
H2AX	BioGRID	CALM2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	BTF3	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	BRCA2	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
H2AX	BioGRID	ANXA6	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ANXA5	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ANXA4	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ANXA2P2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ANXA2	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	SLC25A6	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ALDOA	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	CFAP45	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	POFUT1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	GANAB	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	CCT5	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ERP29	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	PRDX3	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	PRDX4	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	HYOU1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	VAT1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	SYNCRIP	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	ALYREF	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	TRAP1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	PDIA6	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	PDCD6	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	HNRNPDL	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	MATR3	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	TP53I3	GeneID	BioGRID	Affinity Capture-Western; Co-localization
H2AX	BioGRID	PPM1D	GeneID	BioGRID	Affinity Capture-Western; Biochemical Activity
H2AX	BioGRID	MAPK8	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
H2AX	BioGRID	BRD1	GeneID	BioGRID	Reconstituted Complex
H2AX	BioGRID	KAT2B	GeneID	BioGRID	Affinity Capture-Western
H2AX	BioGRID	HAT1	GeneID	BioGRID	Affinity Capture-Western
H2AX	BioGRID	SMARCA2	GeneID	BioGRID	Affinity Capture-Western
H2AX	BioGRID	RPS6KA3	GeneID	BioGRID	Biochemical Activity
H2AX	BioGRID	KAT2A	GeneID	BioGRID	Affinity Capture-Western
H2AX	BioGRID	KAT8	GeneID	BioGRID	Affinity Capture-Western
H2AX	BioGRID	WRN	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
H2AX	BioGRID	RAD17	GeneID	BioGRID	Affinity Capture-Western
H2AX	BioGRID	FOXO3	GeneID	BioGRID	Affinity Capture-Western
H2AX	BioGRID	EEF1A1	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	H4C16	GeneID	BioGRID	Affinity Capture-Western
H2AX	BioGRID	TSSK6	GeneID	BioGRID	Biochemical Activity
H2AX	BioGRID	tat	GeneID	BioGRID	Protein-peptide
H2AX	BioGRID	vpr	GeneID	BioGRID	Co-localization
H2AX	BioGRID	TP53	GeneID	BioGRID	Affinity Capture-Western
H2AX	BioGRID	PTPA	GeneID	BioGRID	Biochemical Activity
H2AX	BioGRID	H2BC4	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	PAPPA	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	CALM1	GeneID	BioGRID	Affinity Capture-MS; Two-hybrid
H2AX	BioGRID	DHX30	GeneID	BioGRID	Affinity Capture-MS
H2AX	BioGRID	PBK	GeneID	BioGRID	Biochemical Activity; Reconstituted Complex
H2AX	BioGRID	EYA3	GeneID	BioGRID	Affinity Capture-Western
H2AX	Protein	MDC1	GeneID	HPRD
H2AX	Protein	PPP1CA	GeneID	HPRD
H2AX	Protein	ALG9	GeneID	HPRD
H2AX	Protein	ATM	GeneID	HPRD
H2AX	Protein	TP53BP1	GeneID	HPRD
H2AX	Protein	WRN	GeneID	HPRD
H2AX	Protein	NBN	GeneID	HPRD
H2AX	Protein	SUPT5H	GeneID	HPRD
H2AX	Protein	H2AX	GeneID	HPRD
H2AX	Protein	MRE11	GeneID	HPRD
H2AX	Protein	BRCA1	GeneID	HPRD
H2AX	Protein	None	None	BIND	The Nuclear Vigilin Complex interacts with and phosphorylates H2AX. This interaction was modeled on a demonstrated interaction between human Nuclear Vigilin Complex and H2AX from an unspecified species.
H2AX	Protein	ATM	GeneID	BIND	ATM phosphorylates the carboxy terminus of H2AX.

StringDB

A	B	experiments	database	textmining	combined score	hadb	nhadb
H2AFX	P4HB	270	0	76	330	2	1
H2AFX	PPARGC1A	0	0	174	173	2	1
H2AFX	BRCA1	897	900	933	999	2	1
H2AFX	STK11	130	0	167	283	2	1
H2AFX	RAF1	0	0	140	172	2	1
H2AFX	EGFR	310	0	394	571	2	1
H2AFX	CFLAR	0	0	162	161	2	1
H2AFX	SLC2A1	0	0	136	180	2	1
H2AFX	NEDD8	270	0	212	498	2	1
H2AFX	TP53	270	0	831	871	2	1
H2AFX	MDM2	0	0	519	522	2	1
H2AFX	BRD4	0	0	248	391	2	1
H2AFX	CLU	270	0	82	301	2	1
H2AFX	APAF1	0	0	285	284	2	1
H2AFX	HDAC6	0	600	235	724	2	1
H2AFX	JAK2	0	0	201	215	2	1
H2AFX	APP	0	0	167	167	2	1
H2AFX	EGR1	0	0	145	170	2	1
H2AFX	CTNNB1	0	900	335	931	2	1
H2AFX	HRAS	0	0	360	391	2	1
H2AFX	CXCL8	0	0	248	248	2	1
H2AFX	STAT1	0	0	171	171	2	1
H2AFX	CTRL	0	0	181	181	2	1
H2AFX	MTOR	0	0	323	379	2	1
H2AFX	RAD51	873	600	747	990	2	1
H2AFX	CXCR4	0	0	167	180	2	1
H2AFX	SIRT2	0	0	304	340	2	1
H2AFX	CREB1	0	0	233	232	2	1
H2AFX	PTBP1	0	0	444	510	2	1
H2AFX	CYP1A1	0	0	251	250	2	1
H2AFX	GAPDH	0	0	519	606	2	1
H2AFX	PML	494	650	170	850	2	1
H2AFX	RELA	0	0	193	210	2	1
H2AFX	CARM1	0	0	155	254	2	1
H2AFX	NFKB1	0	0	150	165	2	1
H2AFX	FBL	0	0	155	286	2	1
H2AFX	DAPK1	0	0	149	165	2	1
H2AFX	JUN	0	600	440	771	2	1
H2AFX	CYP19A1	189	0	84	225	2	1
H2AFX	CDC25C	0	0	560	612	2	1
H2AFX	SOD1	0	0	202	202	2	1
H2AFX	AURKA	0	0	218	442	2	1
H2AFX	BAX	0	0	232	251	2	1
H2AFX	CDKN1A	0	0	561	564	2	1
H2AFX	AR	0	600	294	710	2	1
H2AFX	SOX2	0	0	260	318	2	1
H2AFX	TP73	0	0	148	179	2	1
H2AFX	HSP90AA1	270	0	361	557	2	1
H2AFX	HDAC4	0	600	210	715	2	1
H2AFX	MMP9	0	0	288	288	2	1
H2AFX	MAPK3	0	0	336	343	2	1
H2AFX	SQSTM1	0	0	282	304	2	1
H2AFX	BNIP3	0	0	165	165	2	1
H2AFX	SMAD3	0	0	170	169	2	1
H2AFX	EP300	129	600	328	784	2	1
H2AFX	CDK5	0	0	182	200	2	1
H2AFX	ELAVL1	270	0	108	335	2	1
H2AFX	ALB	0	0	459	485	2	1
H2AFX	CD68	0	0	157	188	2	1
H2AFX	ALK	0	0	144	159	2	1
H2AFX	CDH1	0	0	294	294	2	1
H2AFX	VPS35	270	0	0	296	2	1
H2AFX	SIRT6	0	600	325	747	2	1
H2AFX	MAPK8	675	600	816	974	2	1
H2AFX	DIABLO	0	0	247	246	2	1
H2AFX	SESN2	0	0	134	159	2	1
H2AFX	EGF	0	0	298	298	2	1
H2AFX	CYCS	0	0	504	519	2	1
H2AFX	TRAF6	270	0	151	353	2	1
H2AFX	CD44	0	0	240	239	2	1
H2AFX	MAPK1	0	0	150	159	2	1
H2AFX	IGF1	0	0	194	194	2	1
H2AFX	FGF2	0	0	202	202	2	1
H2AFX	FAU	0	0	0	207	2	1
H2AFX	CCND1	0	900	495	948	2	1
H2AFX	EIF4E	0	0	142	162	2	1
H2AFX	PRKDC	874	650	763	989	2	1
H2AFX	RUNX1	0	600	0	600	2	1
H2AFX	VDAC1	0	0	157	183	2	1
H2AFX	PRKCD	0	0	143	161	2	1
H2AFX	FOXP3	0	0	93	152	2	1
H2AFX	SKP1	0	0	175	189	2	1
H2AFX	TRIM28	481	900	294	969	2	1
H2AFX	MIF	0	0	0	159	2	1
H2AFX	FOXO3	270	0	270	469	2	1
H2AFX	CD34	0	0	242	243	2	1
H2AFX	EIF4EBP1	0	0	285	324	2	1
H2AFX	NOX4	0	0	218	218	2	1
H2AFX	MET	0	0	152	167	2	1
H2AFX	PMAIP1	0	0	390	406	2	1
H2AFX	FOS	0	600	231	679	2	1
H2AFX	SOD2	270	0	241	431	2	1
H2AFX	FOXO1	0	0	242	271	2	1
H2AFX	HSPA5	270	0	218	434	2	1
H2AFX	E2F1	0	0	255	429	2	1
H2AFX	CUL3	0	0	157	202	2	1
H2AFX	SFN	0	0	277	303	2	1
H2AFX	HDAC1	0	600	404	802	2	1
H2AFX	NQO1	0	0	212	212	2	1
H2AFX	TRIB3	0	0	113	166	2	1
H2AFX	USP11	494	0	451	722	2	1
H2AFX	NFKBIA	0	0	234	247	2	1
H2AFX	TP53BP2	0	0	292	292	2	1
H2AFX	MAPK14	0	900	243	921	2	1
H2AFX	PTEN	0	0	402	421	2	1
H2AFX	VEGFA	0	0	294	294	2	1
H2AFX	DNM1L	0	0	107	173	2	1
H2AFX	ATG7	0	0	194	194	2	1
H2AFX	GFAP	0	0	150	170	2	1
H2AFX	ATM	870	900	912	999	2	1
H2AFX	CTSD	270	0	91	364	2	1
H2AFX	RARA	0	600	92	627	2	1
H2AFX	HSPB1	0	0	180	200	2	1
H2AFX	ISG15	0	0	73	204	2	1
H2AFX	ATG5	0	0	201	201	2	1
H2AFX	PCNA	0	0	0	375	2	1
H2AFX	MCL1	0	0	408	420	2	1
H2AFX	SIRT1	0	600	455	803	2	1
H2AFX	HMGB1	0	0	181	337	2	1
H2AFX	PIK3CA	0	0	155	225	2	1
H2AFX	PI3	0	0	294	294	2	1
H2AFX	IGF1R	0	0	218	231	2	1
H2AFX	MYC	0	600	567	827	2	1
H2AFX	AKT2	0	0	144	165	2	1
H2AFX	EHMT2	270	900	218	947	2	1
H2AFX	NFE2L2	0	0	235	235	2	1
H2AFX	HDAC3	0	600	122	707	2	1
H2AFX	DDIT3	0	0	231	230	2	1
H2AFX	LMNA	510	600	317	866	2	1
H2AFX	CDK4	0	600	392	783	2	1
H2AFX	FADD	0	0	174	223	2	1
H2AFX	STAT3	0	0	368	368	2	1
H2AFX	EZH2	0	600	309	792	2	1
H2AFX	AGO2	0	600	125	639	2	1
H2AFX	PAK1	129	0	46	153	2	1
H2AFX	MAP1LC3A	270	0	183	392	2	1
H2AFX	CDK2	0	650	507	855	2	1
H2AFX	SP1	0	0	137	162	2	1
H2AFX	IL1B	0	0	247	246	2	1
H2AFX	HIF1A	270	0	399	543	2	1
H2AFX	RPS6	130	0	174	289	2	1
H2AFX	IL6	0	0	336	337	2	1
H2AFX	MPO	0	0	150	170	2	1
H2AFX	NOTCH1	0	0	262	288	2	1
H2AFX	PLK1	0	600	459	822	2	1
H2AFX	MGMT	0	0	402	403	2	1
H2AFX	ANXA5	270	0	602	698	2	1
H2AFX	TLR4	0	0	136	151	2	1
H2AFX	BCL2L1	0	0	450	461	2	1
H2AFX	PELP1	270	0	0	312	2	1
H2AFX	DNMT3A	270	600	250	804	2	1
H2AFX	RAN	0	650	0	678	2	1
H2AFX	TNFSF10	0	0	155	154	2	1
H2AFX	CHEK1	0	0	805	865	2	1
H2AFX	BCL2L11	0	0	341	341	2	1
H2AFX	VCP	0	0	171	206	2	1
H2AFX	MMP2	0	0	191	191	2	1
H2AFX	TFAM	0	0	394	497	2	1
H2AFX	COIL	0	0	193	193	2	1
H2AFX	KDM1A	0	600	208	807	2	1
H2AFX	HSPA8	0	0	124	193	2	1
H2AFX	PARP1	871	0	710	969	2	1
H2AFX	SIRT7	270	0	254	464	2	1
H2AFX	ZEB1	0	0	170	169	2	1
H2AFX	FBXW7	0	0	181	181	2	1
H2AFX	KEAP1	0	0	243	273	2	1
H2AFX	PROM1	0	0	224	224	2	1
H2AFX	SIRT3	0	0	267	305	2	1
H2AFX	INS	0	0	269	279	2	1
H2AFX	ACTB	64	0	601	680	2	1
H2AFX	DNMT1	160	600	396	823	2	1
H2AFX	STUB1	0	0	123	155	2	1
H2AFX	PGK1	270	0	95	355	2	1
H2AFX	CASP8	0	0	455	455	2	1
H2AFX	MPG	0	0	215	254	2	1
H2AFX	CDK6	0	0	324	380	2	1
H2AFX	VIM	0	0	143	199	2	1
H2AFX	SKP2	0	0	180	198	2	1
H2AFX	CMBL	270	0	391	536	2	1
H2AFX	MAPK9	0	0	155	154	2	1
H2AFX	NANOG	0	0	213	222	2	1
H2AFX	CASP9	0	0	505	505	2	1
H2AFX	USP14	270	0	89	349	2	1
H2AFX	EEF2	0	0	74	199	2	1
H2AFX	TNF	0	0	325	325	2	1
H2AFX	TRAP1	270	0	0	327	2	1
H2AFX	ATF3	0	0	156	155	2	1
H2AFX	ATR	495	600	653	944	2	1
H2AFX	RPS6KB1	0	0	285	284	2	1
H2AFX	CDK1	0	900	556	967	2	1
H2AFX	SON	0	0	327	341	2	1
H2AFX	AHR	0	0	206	206	2	1
H2AFX	POU5F1	0	0	259	258	2	1
H2AFX	CAT	0	0	373	374	2	1
H2AFX	BLM	486	900	397	977	2	1
H2AFX	ACD	0	600	146	656	2	1
H2AFX	TSC2	0	0	167	167	2	1
H2AFX	RB1	0	900	256	924	2	1
H2AFX	CDKN1B	0	0	293	293	2	1
H2AFX	HMOX1	0	0	321	321	2	1
H2AFX	TOMM20	0	0	453	478	2	1
H2AFX	EIF2AK3	0	0	244	243	2	1
H2AFX	SRC	0	0	234	264	2	1
H2AFX	ERBB2	0	0	339	350	2	1
H2AFX	BBC3	0	0	282	302	2	1
H2AFX	BIRC5	270	0	210	590	2	1
H2AFX	KLF4	0	0	164	189	2	1
H2AFX	XIAP	0	0	360	433	2	1
H2AFX	RUNX2	0	0	160	159	2	1
H2AFX	AKT1	0	0	518	543	2	1
H2AFX	PPARG	0	0	155	168	2	1
H2AFX	MKI67	270	0	107	479	2	1
H2AFX	CD4	0	0	234	234	2	1
H2AFX	BECN1	0	0	292	292	2	1
H2AFX	MAPT	270	0	76	321	2	1
H2AFX	ABCB1	0	0	194	206	2	1
H2AFX	PRKAR1A	0	0	0	247	2	1
H2AFX	KRAS	0	0	293	293	2	1
H2AFX	GSK3B	0	0	134	206	2	1
H2AFX	CDKN2A	0	0	506	525	2	1
H2AFX	RIPK1	0	0	162	176	2	1
H2AFX	CASP3	0	0	683	685	2	1
H2AFX	PTGS2	0	0	236	236	2	1
H2AFX	CYBB	0	0	279	279	2	1
H2AFX	TNFRSF10B	0	0	235	235	2	1
H2AFX	KIT	0	0	211	217	2	1
H2AFX	FLT3	0	0	166	165	2	1
H2AFX	OGT	0	0	82	291	2	1
H2AFX	ULK1	270	0	453	594	2	1
H2AFX	FN1	0	0	210	210	2	1
H2AFX	TERT	0	0	335	384	2	1
H2AFX	MAP1LC3B	0	0	321	336	2	1
H2AFX	UBC	270	900	81	939	2	1
H2AFX	YAP1	0	0	155	187	2	1
H2AFX	ESR1	44	600	340	729	2	1
H2AFX	NCL	270	0	204	426	2	1
H2AFX	UBQLN2	0	0	0	167	2	1

Ontologies

ID	Category	Term	Effect	Evidence
GO:0003677	Molecular Function	DNA binding	enables	IBA
GO:0003677	Molecular Function	DNA binding	enables	NAS
GO:0003684	Molecular Function	damaged DNA binding	enables	IEA
GO:0019899	Molecular Function	enzyme binding	enables	IPI
GO:0042393	Molecular Function	histone binding	enables	IPI
GO:0005515	Molecular Function	protein binding	enables	IPI
GO:0046982	Molecular Function	protein heterodimerization activity	enables	IEA
GO:0030527	Molecular Function	structural constituent of chromatin	enables	IEA
GO:0000077	Biological Process	DNA damage checkpoint signaling	involved_in	IDA
GO:0006974	Biological Process	DNA damage response	involved_in	IBA
GO:0006974	Biological Process	DNA damage response	involved_in	IDA
GO:0006974	Biological Process	DNA damage response	involved_in	IMP
GO:0071480	Biological Process	cellular response to gamma radiation	involved_in	IEA
GO:0090398	Biological Process	cellular senescence	involved_in	IEA
GO:0021987	Biological Process	cerebral cortex development	involved_in	IEA
GO:0006302	Biological Process	double-strand break repair	involved_in	NAS
GO:0000724	Biological Process	double-strand break repair via homologous recombination	involved_in	IEA
GO:0051321	Biological Process	meiotic cell cycle	involved_in	IEA
GO:0006334	Biological Process	nucleosome assembly	involved_in	NAS
GO:0045739	Biological Process	positive regulation of DNA repair	involved_in	NAS
GO:0010212	Biological Process	response to ionizing radiation	involved_in	NAS
GO:0007283	Biological Process	spermatogenesis	involved_in	IEA
GO:0001741	Cellular Component	XY body	located_in	IEA
GO:0005813	Cellular Component	centrosome	located_in	IDA
GO:0000781	Cellular Component	chromosome, telomeric region	colocalizes_with	IDA
GO:0000794	Cellular Component	condensed nuclear chromosome	located_in	IEA
GO:0070062	Cellular Component	extracellular exosome	located_in	HDA
GO:0001673	Cellular Component	male germ cell nucleus	located_in	IEA
GO:0016607	Cellular Component	nuclear speck	located_in	IDA
GO:0005654	Cellular Component	nucleoplasm	located_in	IDA
GO:0005654	Cellular Component	nucleoplasm	located_in	TAS
GO:0000786	Cellular Component	nucleosome	part_of	IEA
GO:0005634	Cellular Component	nucleus	located_in	HDA
GO:0005634	Cellular Component	nucleus	located_in	IDA
GO:0005634	Cellular Component	nucleus	located_in	IMP
GO:0005657	Cellular Component	replication fork	located_in	IEA
GO:0090734	Cellular Component	site of DNA damage	located_in	IMP
GO:0035861	Cellular Component	site of double-strand break	located_in	IDA

Pathways

Name	DB	ID
Recognition and association of DNA glycosylase with site containing an affected pyrimidine	Reactome	R-HSA-110328
Cleavage of the damaged pyrimidine	Reactome	R-HSA-110329
Recognition and association of DNA glycosylase with site containing an affected purine	Reactome	R-HSA-110330
Cleavage of the damaged purine	Reactome	R-HSA-110331
Meiotic synapsis	Reactome	R-HSA-1221632
Developmental Biology	Reactome	R-HSA-1266738
Reproduction	Reactome	R-HSA-1474165
Meiosis	Reactome	R-HSA-1500620
Signaling by NOTCH	Reactome	R-HSA-157118
Telomere Maintenance	Reactome	R-HSA-157579
Signal Transduction	Reactome	R-HSA-162582
Cell Cycle	Reactome	R-HSA-1640170
Disease	Reactome	R-HSA-1643685
Packaging Of Telomere Ends	Reactome	R-HSA-171306
Pre-NOTCH Transcription and Translation	Reactome	R-HSA-1912408
Pre-NOTCH Expression and Processing	Reactome	R-HSA-1912422
Signaling by Rho GTPases	Reactome	R-HSA-194315
RHO GTPase Effectors	Reactome	R-HSA-195258
Signaling by WNT	Reactome	R-HSA-195721
TCF dependent signaling in response to WNT	Reactome	R-HSA-201681
Formation of the beta-catenin:TCF transactivating complex	Reactome	R-HSA-201722
Gene Silencing by RNA	Reactome	R-HSA-211000
Epigenetic regulation of gene expression	Reactome	R-HSA-212165
PRC2 methylates histones and DNA	Reactome	R-HSA-212300
Generic Transcription Pathway	Reactome	R-HSA-212436
Cellular responses to stress	Reactome	R-HSA-2262752
Condensation of Prophase Chromosomes	Reactome	R-HSA-2299718
Oxidative Stress Induced Senescence	Reactome	R-HSA-2559580
Senescence-Associated Secretory Phenotype (SASP)	Reactome	R-HSA-2559582
Cellular Senescence	Reactome	R-HSA-2559583
DNA Damage/Telomere Stress Induced Senescence	Reactome	R-HSA-2559586
RMTs methylate histone arginines	Reactome	R-HSA-3214858
Chromatin modifying enzymes	Reactome	R-HSA-3247509
Metabolism of proteins	Reactome	R-HSA-392499
SIRT1 negatively regulates rRNA expression	Reactome	R-HSA-427359
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression	Reactome	R-HSA-427389
NoRC negatively regulates rRNA expression	Reactome	R-HSA-427413
Chromatin organization	Reactome	R-HSA-4839726
Positive epigenetic regulation of rRNA expression	Reactome	R-HSA-5250913
B-WICH complex positively regulates rRNA expression	Reactome	R-HSA-5250924
Negative epigenetic regulation of rRNA expression	Reactome	R-HSA-5250941
DNA methylation	Reactome	R-HSA-5334118
Transcriptional regulation by small RNAs	Reactome	R-HSA-5578749
Activation of anterior HOX genes in hindbrain development during early embryogenesis	Reactome	R-HSA-5617472
Activation of HOX genes during differentiation	Reactome	R-HSA-5619507
RHO GTPases activate PKNs	Reactome	R-HSA-5625740
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3	Reactome	R-HSA-5625886
DNA Double-Strand Break Repair	Reactome	R-HSA-5693532
Homology Directed Repair	Reactome	R-HSA-5693538
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks	Reactome	R-HSA-5693565
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)	Reactome	R-HSA-5693567
Nonhomologous End-Joining (NHEJ)	Reactome	R-HSA-5693571
DNA Double Strand Break Response	Reactome	R-HSA-5693606
Processing of DNA double-strand break ends	Reactome	R-HSA-5693607
Deposition of new CENPA-containing nucleosomes at the centromere	Reactome	R-HSA-606279
Assembly of the ORC complex at the origin of replication	Reactome	R-HSA-68616
Assembly of the pre-replicative complex	Reactome	R-HSA-68867
Mitotic Prophase	Reactome	R-HSA-68875
M Phase	Reactome	R-HSA-68886
DNA Replication Pre-Initiation	Reactome	R-HSA-69002
Cell Cycle, Mitotic	Reactome	R-HSA-69278
DNA Replication	Reactome	R-HSA-69306
G2/M DNA damage checkpoint	Reactome	R-HSA-69473
G2/M Checkpoints	Reactome	R-HSA-69481
Cell Cycle Checkpoints	Reactome	R-HSA-69620
RNA Polymerase I Promoter Opening	Reactome	R-HSA-73728
RNA Polymerase I Promoter Escape	Reactome	R-HSA-73772
RNA Polymerase I Promoter Clearance	Reactome	R-HSA-73854
RNA Polymerase II Transcription	Reactome	R-HSA-73857
RNA Polymerase I Transcription	Reactome	R-HSA-73864
Base Excision Repair	Reactome	R-HSA-73884
Chromosome Maintenance	Reactome	R-HSA-73886
DNA Repair	Reactome	R-HSA-73894
Depurination	Reactome	R-HSA-73927
Depyrimidination	Reactome	R-HSA-73928
Base-Excision Repair, AP Site Formation	Reactome	R-HSA-73929
Gene expression (Transcription)	Reactome	R-HSA-74160
Nucleosome assembly	Reactome	R-HSA-774815
Transcriptional regulation by RUNX1	Reactome	R-HSA-8878171
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	Reactome	R-HSA-8936459
ESR-mediated signaling	Reactome	R-HSA-8939211
RUNX1 regulates transcription of genes involved in differentiation of HSCs	Reactome	R-HSA-8939236
Cellular responses to stimuli	Reactome	R-HSA-8953897
Signaling by Nuclear Receptors	Reactome	R-HSA-9006931
Estrogen-dependent gene expression	Reactome	R-HSA-9018519
Meiotic recombination	Reactome	R-HSA-912446
Transcriptional regulation of granulopoiesis	Reactome	R-HSA-9616222
Diseases of programmed cell death	Reactome	R-HSA-9645723
Inhibition of DNA recombination at telomere	Reactome	R-HSA-9670095
Defective pyroptosis	Reactome	R-HSA-9710421
Signaling by Rho GTPases, Miro GTPases and RHOBTB3	Reactome	R-HSA-9716542
Amyloid fiber formation	Reactome	R-HSA-977225
DNA IR-double strand breaks and cellular response via ATM (WP3959)	WikiPathways	WP3959_r118468
7q11.23 copy number variation syndrome (WP4932)	WikiPathways	WP4932_r118797
ATM signaling pathway (WP2516)	WikiPathways	WP2516_r116808
Proteasome degradation (WP183)	WikiPathways	WP183_r117060
NIPBL role in DNA damage - Cornelia de Lange syndrome (WP5119)	WikiPathways	WP5119_r119393
DNA IR-damage and cellular response via ATR (WP4016)	WikiPathways	WP4016_r120667
DNA repair pathways, full network (WP4946)	WikiPathways	WP4946_r117703
ATM signaling in development and disease (WP3878)	WikiPathways	WP3878_r123399
FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma (WP4553)	WikiPathways	WP4553_r103606
DNA damage response (WP707)	WikiPathways	WP707_r124174
miRNAs involved in DNA damage response (WP1545)	WikiPathways	WP1545_r118363
miRNA regulation of DNA damage response (WP1530)	WikiPathways	WP1530_r124175

Transcripts

Accession	Version	MolecularType	Name	NCBI	Comments
NM_002105	3	mRNA	None	NC_000011	Reference