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HES1

hes family bHLH transcription factor 1
General Information
Name hes family bHLH transcription factor 1
Alias
  • transcription factor HES-1
  • class B basic helix-loop-helix protein 39
  • hairy homolog
  • hairy-like protein
Gene_family Basic helix-loop-helix proteins
organism Homo sapiens
entrez_id 3280
location 3q29
transcript_count 1
exon_count 4
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez This protein belongs to the basic helix-loop-helix family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. The protein has a particular type of basic domain that contains a helix interrupting protein that binds to the N-box rather than the canonical E-box. [provided by RefSeq, Jul 2008]
    Stringdb Transcription factor HES-1; Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity). May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage; Basic helix-loop- [...]
    nextProt Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity). May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage.
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
HES1 BioGRID HES6 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
HES1 BioGRID HES1 GeneID BioGRID Affinity Capture-Western; Co-crystal Structure
HES1 BioGRID ALK GeneID BioGRID Biochemical Activity
HES1 BioGRID ZFP64 GeneID BioGRID Co-localization
HES1 BioGRID ZNF70 GeneID BioGRID Co-localization
HES1 BioGRID RBPJ GeneID BioGRID Affinity Capture-Western; Co-crystal Structure
HES1 BioGRID RUNX2 GeneID BioGRID Affinity Capture-Western; Co-localization; Reconstituted Complex
HES1 BioGRID RB1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
HES1 BioGRID TLE1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
HES1 BioGRID PIN1 GeneID BioGRID Affinity Capture-Western
HES1 BioGRID ASCL1 GeneID BioGRID Co-localization
HES1 BioGRID HEY1 GeneID BioGRID Affinity Capture-MS; Reconstituted Complex
HES1 BioGRID LMNA GeneID BioGRID Co-localization
HES1 BioGRID UBC GeneID BioGRID Affinity Capture-Western
HES1 BioGRID HEXIM1 GeneID BioGRID Affinity Capture-MS
HES1 BioGRID TNIP2 GeneID BioGRID Affinity Capture-RNA
HES1 BioGRID FBXL14 GeneID BioGRID Affinity Capture-Western
HES1 BioGRID CUL1 GeneID BioGRID Affinity Capture-Western
HES1 BioGRID SKP1 GeneID BioGRID Affinity Capture-Western
HES1 BioGRID LMO3 GeneID BioGRID Affinity Capture-Western; Phenotypic Suppression
HES1 BioGRID NHLH2 GeneID BioGRID Affinity Capture-Western; Phenotypic Suppression; Reconstituted Complex
HES1 BioGRID UL123 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
HES1 BioGRID FANCG GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Two-hybrid
HES1 BioGRID FANCF GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Two-hybrid
HES1 BioGRID FANCE GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
HES1 BioGRID FANCA GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Two-hybrid
HES1 BioGRID STAT3 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
HES1 BioGRID JAK2 GeneID BioGRID Affinity Capture-Western
HES1 BioGRID APH1A GeneID BioGRID Two-hybrid
HES1 BioGRID LTBR GeneID BioGRID Two-hybrid
HES1 BioGRID ASGR2 GeneID BioGRID Two-hybrid
HES1 BioGRID ELAVL1 GeneID BioGRID Affinity Capture-RNA
HES1 BioGRID PARP1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
HES1 BioGRID NUDT3 GeneID BioGRID Two-hybrid
HES1 BioGRID HDAC6 GeneID BioGRID Two-hybrid
HES1 BioGRID YWHAB GeneID BioGRID Two-hybrid
HES1 BioGRID PTK2 GeneID BioGRID Two-hybrid
HES1 BioGRID NR4A1 GeneID BioGRID Two-hybrid
HES1 BioGRID HMGCL GeneID BioGRID Two-hybrid
HES1 BioGRID GAPDH GeneID BioGRID Two-hybrid
HES1 BioGRID FHL1 GeneID BioGRID Two-hybrid
HES1 BioGRID CSNK1E GeneID BioGRID Two-hybrid
HES1 BioGRID APCS GeneID BioGRID Two-hybrid
HES1 BioGRID FANCC GeneID BioGRID Affinity Capture-Western
HES1 BioGRID FANCL GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Two-hybrid
HES1 BioGRID SPTAN1 GeneID BioGRID Affinity Capture-MS
HES1 BioGRID HSP90AA1 GeneID BioGRID Affinity Capture-MS
HES1 BioGRID HSPA4 GeneID BioGRID Affinity Capture-MS
HES1 BioGRID HDAC1 GeneID BioGRID Affinity Capture-Western
HES1 Protein HES6 GeneID HPRD
HES1 Protein ID4 GeneID HPRD
HES1 Protein ID1 GeneID HPRD
HES1 Protein SIRT1 GeneID HPRD
HES1 Protein FANCL GeneID HPRD
HES1 Protein FANCA GeneID HPRD
HES1 Protein UBQLN1 GeneID HPRD
HES1 Protein HEY2 GeneID HPRD
HES1 Protein FANCF GeneID HPRD
HES1 Protein FANCG GeneID HPRD
HES1 Protein FANCE GeneID HPRD
HES1 Protein ID2 GeneID HPRD
HES1 Protein ID3 GeneID HPRD
HES1 Protein TLE1 GeneID HPRD
HES1 Protein PRKCA GeneID HPRD
HES1 Protein FOXG1 GeneID HPRD
HES1 Protein HMGB1 GeneID HPRD
HES1 Protein JAK2 GeneID HPRD
HES1 Protein STAT3 GeneID HPRD
HES1 BioGRID TLE2 GeneID BioGRID Reconstituted Complex; Two-hybrid
HES1 BioGRID HEY2 GeneID BioGRID Reconstituted Complex
HES1 BioGRID SIRT1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
HES1 Nucleotide POLR2A GeneID BIND HES1 promoter interacts with RNAPII.
HES1 Nucleotide HES1 GeneID BIND HES1 promoter interacts with HES1.
HES1 Nucleotide SUPT16H GeneID BIND HES1 promoter interacts with FACT.
HES1 Nucleotide RBPJ GeneID BIND HES1 promoter interacts with CBF1.
StringDB
A B experiments database textmining combined score hadb nhadb
HES1 EGR1 0 0 143 178 1 2
HES1 NAPRT 0 0 102 167 1 1
HES1 MYF5 0 0 81 208 1 1
HES1 HRAS 0 0 141 180 1 2
HES1 CTNNB1 0 0 349 373 1 2
HES1 MSI1 0 0 218 218 1 1
HES1 IKBKE 0 0 49 173 1 1
HES1 WNT2B 0 0 45 152 1 1
HES1 SGCD 0 0 48 194 1 1
HES1 NKX6-2 0 0 163 209 1 1
HES1 MATN4 0 0 0 182 1 1
HES1 ZMYM3 0 0 67 210 1 1
HES1 ISL1 0 0 134 189 1 1
HES1 SIRT5 0 0 46 169 1 1
HES1 EN2 0 0 0 202 1 1
HES1 HIF1A 0 0 418 427 1 2
HES1 GBX2 0 0 85 200 1 1
HES1 PAX2 0 0 48 190 1 1
HES1 ID1 213 0 241 546 1 1
HES1 NPAS2 0 0 70 151 1 1
HES1 IL6 0 0 205 205 1 2
HES1 NFYB 0 0 0 207 1 1
HES1 KCTD1 0 0 108 347 1 1
HES1 TCF15 0 0 0 285 1 1
HES1 ETS2 0 0 0 305 1 1
HES1 MYOG 0 0 81 165 1 1
HES1 ATRIP 0 900 0 900 1 1
HES1 ELAVL3 0 0 70 282 1 1
HES1 STAT1 0 900 70 906 1 2
HES1 POU4F2 0 0 0 206 1 1
HES1 ENSG00000278882 0 0 0 280 1 1
HES1 NOTCH1 270 900 752 985 1 2
HES1 OPA3 0 0 398 398 1 1
HES1 CXCR4 0 0 143 162 1 2
HES1 FGF13 0 0 95 190 1 1
HES1 SMO 0 0 74 192 1 1
HES1 MTOR 0 0 143 172 1 2
HES1 FOXM1 0 0 166 184 1 1
HES1 CCNB1 0 0 114 160 1 1
HES1 ANXA5 0 0 143 163 1 2
HES1 MYT1L 0 0 0 189 1 1
HES1 RELN 0 0 47 152 1 1
HES1 UBE2B 0 0 61 160 1 1
HES1 SIRT2 0 0 61 151 1 2
HES1 TRIP12 0 0 0 153 1 1
HES1 CREBBP 0 900 103 922 1 1
HES1 NOTCH4 0 900 414 951 1 1
HES1 ESRRA 0 0 410 428 1 1
HES1 CREB1 0 0 194 194 1 2
HES1 BTF3L4 0 0 150 228 1 1
HES1 TAL2 0 0 0 152 1 1
HES1 OLIG1 0 0 140 185 1 1
HES1 HEYL 0 650 324 691 1 1
HES1 GAPDH 59 0 324 351 1 2
HES1 FAM107A 0 0 0 422 1 1
HES1 SMAD2 0 0 122 159 1 2
HES1 TOPORS 0 0 0 165 1 1
HES1 SPDEF 0 0 242 266 1 1
HES1 EBF1 0 0 53 183 1 1
HES1 DNAI1 0 0 0 189 1 1
HES1 SNW1 0 900 74 903 1 1
HES1 GRHL1 0 0 0 258 1 1
HES1 JAG2 0 0 460 582 1 1
HES1 FANCB 0 900 0 907 1 1
HES1 USP27X 0 0 171 171 1 1
HES1 ZIC1 0 0 0 315 1 1
HES1 SOX3 0 0 54 166 1 1
HES1 PTPN14 0 0 0 156 1 1
HES1 RELA 0 0 91 152 1 2
HES1 NFKB1 0 0 0 153 1 2
HES1 C19orf40 0 900 0 922 1 1
HES1 DVL1 0 0 60 180 1 1
HES1 EVX1 0 0 0 254 1 1
HES1 NOG 0 0 100 161 1 1
HES1 TOP3A 0 900 0 901 1 1
HES1 WWTR1 0 0 90 251 1 1
HES1 LMO3 270 0 95 337 1 1
HES1 NCSTN 0 0 233 250 1 1
HES1 PAX7 0 0 69 239 1 1
HES1 WNT5A 0 0 125 174 1 2
HES1 PURA 0 0 0 181 1 1
HES1 FABP7 0 0 129 159 1 1
HES1 MATN2 0 0 0 182 1 1
HES1 MYC 270 0 297 474 1 2
HES1 SLC1A3 0 0 43 167 1 1
HES1 FGF10 0 0 100 239 1 1
HES1 MT3 0 0 90 152 1 1
HES1 ADAM10 0 0 202 251 1 1
HES1 HES6 213 900 242 931 1 1
HES1 NR2C1 0 0 0 161 1 1
HES1 SDHC 0 0 166 165 1 1
HES1 C2orf69 0 0 0 206 1 1
HES1 MNX1 0 0 138 241 1 1
HES1 NKX6-1 0 0 171 284 1 1
HES1 TCF3 0 0 108 321 1 1
HES1 PITX1 0 0 0 163 1 1
HES1 ASGR1 0 0 0 542 1 1
HES1 CHGA 0 0 218 218 1 1
HES1 SMAD4 0 0 143 165 1 2
HES1 LRP5 0 0 95 187 1 1
HES1 MYCN 0 0 150 216 1 1
HES1 EBF2 0 0 0 173 1 1
HES1 PARD3 0 0 68 191 1 1
HES1 NCOR2 0 0 162 168 1 1
HES1 LMX1B 0 0 0 154 1 1
HES1 ASPH 0 0 150 281 1 1
HES1 RMI1 0 900 0 900 1 1
HES1 GAA 0 0 602 602 1 2
HES1 TP53 0 0 283 282 1 2
HES1 MDM2 0 0 270 270 1 2
HES1 PRKCI 0 0 0 281 1 1
HES1 FAM120C 0 0 160 159 1 1
HES1 CDK4 0 0 308 307 1 2
HES1 EGFR 0 0 206 242 1 2
HES1 ZP1 0 0 260 260 1 1
HES1 HNRNPR 0 0 0 189 1 1
HES1 GATA3 0 0 149 262 1 1
HES1 ELAVL2 0 0 0 260 1 1
HES1 NR2F1 0 0 92 255 1 1
HES1 TCF21 0 0 69 170 1 1
HES1 GSX2 0 0 48 211 1 1
HES1 UBE2T 0 900 0 900 1 1
HES1 STAT3 270 900 261 947 1 2
HES1 FANCC 270 900 0 931 1 1
HES1 HBEGF 0 0 81 172 1 1
HES1 RFC3 0 900 0 901 1 1
HES1 HOXC5 0 0 0 161 1 1
HES1 ST18 0 0 0 189 1 1
HES1 CDH2 0 0 124 150 1 1
HES1 JAK2 270 900 463 958 1 2
HES1 RAD9A 0 900 0 900 1 1
HES1 MAML2 0 900 52 909 1 1
HES1 CTBP2 0 0 70 460 1 1
HES1 PAX4 0 0 205 235 1 1
HES1 NOTCH3 0 900 505 962 1 1
HES1 CSNK2A2 0 0 0 177 1 1
HES1 NUMB 0 0 335 479 1 1
HES1 LEF1 0 0 150 183 1 1
HES1 EP300 0 900 122 919 1 2
HES1 HNF1B 0 0 256 271 1 1
HES1 VSX1 0 0 0 199 1 1
HES1 ONECUT1 0 0 235 290 1 1
HES1 SMAD3 0 0 188 188 1 2
HES1 PHACTR1 0 0 0 190 1 1
HES1 CRY2 0 0 0 196 1 1
HES1 DCLK1 0 0 152 151 1 1
HES1 VRTN 0 0 134 285 1 1
HES1 ALB 0 0 167 179 1 2
HES1 SFRP5 0 0 95 151 1 1
HES1 SNAI2 0 0 135 522 1 1
HES1 CUL1 270 0 74 295 1 1
HES1 INO80C 0 0 0 177 1 1
HES1 ARMC4 0 0 0 188 1 1
HES1 LRRC6 0 0 0 188 1 1
HES1 NPAS1 0 0 102 213 1 1
HES1 ELAVL1 42 0 0 170 1 2
HES1 ZMYM4 0 0 134 277 1 1
HES1 KAT2A 0 900 61 905 1 1
HES1 ZNF267 0 0 163 323 1 1
HES1 GATA1 0 900 75 914 1 1
HES1 DLL3 0 0 390 438 1 1
HES1 FANCM 0 900 0 906 1 1
HES1 TEAD3 0 0 400 430 1 1
HES1 WNT1 0 0 123 183 1 2
HES1 PAX6 0 0 246 412 1 1
HES1 CUX1 0 0 74 160 1 1
HES1 NEUROG3 0 900 499 949 1 1
HES1 SIRT6 0 0 60 288 1 2
HES1 GLI2 0 0 219 245 1 2
HES1 HES7 0 0 290 245 1 1
HES1 NEUROG2 0 0 276 351 1 1
HES1 CDH1 0 0 236 262 1 2
HES1 DDX55 0 0 0 188 1 1
HES1 ZEB2 0 0 134 173 1 1
HES1 TMEM126A 0 0 434 434 1 1
HES1 MEIS2 0 0 52 166 1 1
HES1 CBFA2T3 0 0 140 200 1 1
HES1 FZD7 0 0 81 160 1 1
HES1 VIM 0 0 56 166 1 2
HES1 SCRT2 0 0 0 164 1 1
HES1 BHLHE40 0 900 143 904 1 1
HES1 ZIC5 0 0 0 271 1 1
HES1 NR2E1 0 0 52 416 1 1
HES1 BHLHE23 0 0 0 200 1 1
HES1 HIST2H3PS2 0 0 159 205 1 1
HES1 SMU1 0 0 108 172 1 1
HES1 SAMD11 0 0 0 208 1 1
HES1 ISM1 0 0 0 302 1 1
HES1 NR3C1 0 0 142 168 1 1
HES1 HES5 0 800 505 840 1 1
HES1 CDKN1C 0 0 140 346 1 1
HES1 NRARP 0 0 116 293 1 1
HES1 PER3 0 0 0 159 1 1
HES1 HSPA4 270 0 0 270 1 1
HES1 GATA4 0 0 170 263 1 2
HES1 RAD17 0 900 0 900 1 1
HES1 GGT6 0 0 0 188 1 1
HES1 FANCE 675 900 0 969 1 1
HES1 NGB 0 0 60 228 1 1
HES1 NES 0 0 285 325 1 2
HES1 SRRT 0 0 247 263 1 1
HES1 NANOG 0 0 259 258 1 2
HES1 ETS1 0 0 66 323 1 1
HES1 C17orf70 0 900 0 917 1 1
HES1 INSM2 0 0 0 189 1 1
HES1 EGF 0 0 263 268 1 2
HES1 BMP2 0 0 183 224 1 1
HES1 OLFM4 0 0 162 232 1 1
HES1 NKAIN3 0 0 0 191 1 1
HES1 HNF1A 0 0 398 398 1 1
HES1 DTX1 0 0 335 340 1 1
HES1 CHEK1 0 900 0 900 1 2
HES1 GRHL2 0 0 0 277 1 1
HES1 PER2 0 0 0 161 1 1
HES1 PTPN21 0 0 0 156 1 1
HES1 RFC2 0 900 0 900 1 1
HES1 PROP1 0 0 49 157 1 1
HES1 SI 0 0 734 734 1 1
HES1 PTCRA 0 0 213 213 1 1
HES1 MAML1 0 900 324 933 1 1
HES1 NR2F2 0 0 122 315 1 1
HES1 DLL4 0 0 466 535 1 1
HES1 KIAA1958 0 0 229 285 1 1
HES1 CBFA2T2 0 0 107 189 1 1
HES1 DVL3 0 0 0 244 1 1
HES1 JUN 0 0 218 235 1 2
HES1 WDFY2 0 0 0 250 1 1
HES1 JAG1 0 0 652 749 1 1
HES1 ASCL2 0 0 182 259 1 1
HES1 HIP1 0 0 139 202 1 1
HES1 TLE4 0 600 0 826 1 1
HES1 NKX2-2 0 0 181 232 1 1
HES1 SHH 0 0 322 353 1 2
HES1 FERD3L 0 0 208 364 1 1
HES1 FGF6 0 0 0 169 1 1
HES1 BMI1 0 0 265 265 1 1
HES1 ARNT 0 0 107 187 1 2
HES1 RPA2 0 900 0 900 1 1
HES1 BMP6 0 0 150 176 1 1
HES1 WDFY1 0 0 94 533 1 1
HES1 QRICH1 0 0 166 165 1 1
HES1 DLL1 0 0 529 594 1 1
HES1 FANCA 486 900 388 965 1 1
HES1 SLC35C2 0 0 0 235 1 1
HES1 RUNX3 0 900 47 900 1 1
HES1 TCF7 0 0 128 182 1 1
HES1 ID4 213 0 217 382 1 1
HES1 TRIM3 0 0 0 370 1 1
HES1 BARHL2 0 0 0 360 1 1
HES1 YY2 0 0 90 164 1 1
HES1 CDKN1A 0 0 195 200 1 2
HES1 NR1D2 0 0 0 176 1 1
HES1 VSX2 0 0 96 292 1 1
HES1 RSL24D1 0 0 270 270 1 1
HES1 AR 0 0 134 160 1 2
HES1 PARP1 270 900 57 926 1 2
HES1 EPCAM 0 0 134 162 1 2
HES1 KDM1A 0 0 91 204 1 2
HES1 RPL24 0 0 266 266 1 1
HES1 BAX 0 0 194 194 1 2
HES1 FGFBP3 0 0 134 193 1 1
HES1 LMX1A 0 0 89 150 1 1
HES1 MIXL1 0 0 0 236 1 1
HES1 SIRT7 0 0 46 157 1 2
HES1 SOX9 0 0 364 428 1 1
HES1 ZEB1 0 0 181 198 1 2
HES1 CD24 0 0 181 181 1 2
HES1 NEUROG1 0 0 216 438 1 1
HES1 FOXD3 0 0 49 230 1 1
HES1 FEZF1 0 0 0 446 1 1
HES1 HSP90AA1 270 0 61 285 1 2
HES1 CTBP1 0 0 166 516 1 1
HES1 POFUT1 0 0 124 214 1 1
HES1 FBXW7 0 0 174 188 1 2
HES1 NEUROD1 0 0 377 430 1 1
HES1 SOX2 0 0 293 324 1 2
HES1 CEBPA 0 0 180 215 1 1
HES1 EXD1 0 0 0 213 1 1
HES1 PSEN1 0 0 170 221 1 2
HES1 RFC4 0 900 0 900 1 1
HES1 EBF4 0 0 0 155 1 1
HES1 ACTB 0 0 310 315 1 2
HES1 INS 0 0 236 236 1 2
HES1 FOXG1 213 0 0 308 1 1
HES1 TLE6 0 0 91 242 1 1
HES1 TLE1 678 900 478 992 1 1
HES1 PRDM14 0 0 0 204 1 1
HES1 HOXA5 0 0 0 221 1 1
HES1 MAPK3 0 0 134 193 1 2
HES1 MMP9 0 0 159 158 1 2
HES1 PAX5 0 0 53 194 1 1
HES1 SIRT3 0 0 76 165 1 2
HES1 PROM1 0 0 291 290 1 2
HES1 CSNK1E 68 0 0 168 1 1
HES1 GLI3 0 0 181 245 1 1
HES1 MFNG 0 0 243 261 1 1
HES1 HEXIM1 270 0 0 270 1 1
HES1 RB1 0 900 90 914 1 2
HES1 DYNLRB2 0 0 0 156 1 1
HES1 ASPHD2 0 0 103 198 1 1
HES1 CDKN1B 0 0 204 209 1 2
HES1 MSX2 0 0 60 262 1 1
HES1 RAX 0 0 0 220 1 1
HES1 AES 0 0 66 283 1 1
HES1 KRT19 0 0 166 233 1 1
HES1 YY1 0 0 608 640 1 1
HES1 SKP1 270 0 81 300 1 2
HES1 RBPJL 0 0 181 224 1 1
HES1 NEUROD4 0 0 165 237 1 1
HES1 PEG3 0 0 414 424 1 2
HES1 DYNLRB1 0 0 0 156 1 1
HES1 MCTS1 0 0 89 151 1 1
HES1 DCX 0 0 161 199 1 1
HES1 HNF4A 0 0 194 194 1 1
HES1 TCF12 0 0 45 384 1 1
HES1 CDKN3 0 0 124 158 1 1
HES1 CAMK2D 0 900 0 902 1 1
HES1 HOXB6 0 0 46 161 1 1
HES1 SRC 0 0 112 156 1 2
HES1 DKK1 0 0 120 166 1 1
HES1 SIN3B 270 0 0 275 1 1
HES1 EPHB3 0 0 170 197 1 1
HES1 CRY1 0 0 0 196 1 1
HES1 SPTAN1 270 0 0 270 1 1
HES1 BGLAP 0 0 183 183 1 1
HES1 GATA5 0 0 74 214 1 1
HES1 FOXO3 0 0 134 171 1 2
HES1 LIFR 0 0 44 189 1 1
HES1 FEZF2 0 0 0 446 1 1
HES1 ERBB2 0 0 123 158 1 2
HES1 CD34 0 0 156 177 1 2
HES1 CSNK2A3 0 0 0 177 1 1
HES1 NOTCH2NL 0 0 95 321 1 1
HES1 TRIM2 0 0 0 370 1 1
HES1 FANCD2 0 900 358 933 1 1
HES1 NHLH2 270 0 123 395 1 1
HES1 MGAM 0 0 732 732 1 1
HES1 SP5 0 0 0 171 1 1
HES1 CCNE2 0 0 72 250 1 1
HES1 INSC 0 0 0 549 1 1
HES1 FBN1 0 0 0 182 1 1
HES1 CIR1 0 0 181 181 1 1
HES1 CRB1 0 0 0 280 1 1
HES1 FAM183B 0 0 0 190 1 1
HES1 SPATA31D1 0 0 0 208 1 1
HES1 ID2 213 0 235 474 1 1
HES1 FOXE1 0 0 107 154 1 1
HES1 PHGDH 0 0 42 176 1 1
HES1 GSK3A 0 0 57 187 1 1
HES1 ATOH1 0 0 470 765 1 1
HES1 BCL6 0 0 61 171 1 1
HES1 UBQLN1 213 0 0 213 1 1
HES1 FBXL14 270 0 173 370 1 1
HES1 DLG1 0 0 62 155 1 1
HES1 LGR6 0 0 66 210 1 1
HES1 RUNX2 270 900 444 958 1 2
HES1 HUS1 0 900 0 900 1 1
HES1 KLF4 0 0 181 213 1 2
HES1 FOXA1 0 0 117 197 1 1
HES1 ZNF396 0 0 180 195 1 1
HES1 TMED2 0 0 0 341 1 1
HES1 AKT1 0 0 323 357 1 2
HES1 PPARG 0 0 195 219 1 2
HES1 FBN3 0 0 0 182 1 1
HES1 LHX2 0 0 72 170 1 1
HES1 FBN2 0 0 44 184 1 1
HES1 RBFOX3 0 0 150 168 1 1
HES1 DNAJC8 0 0 134 188 1 1
HES1 POU2F1 0 0 0 190 1 1
HES1 PAX3 0 0 131 289 1 1
HES1 CLEC10A 0 0 0 301 1 1
HES1 CD44 0 0 232 231 1 2
HES1 MSX1 0 0 0 315 1 1
HES1 RNF4 0 0 0 152 1 1
HES1 ASCL4 0 0 113 196 1 1
HES1 TNF 0 0 141 175 1 2
HES1 QTRTD1 0 0 0 207 1 1
HES1 LHX9 0 0 49 158 1 1
HES1 NFYC 0 0 66 157 1 1
HES1 IGF1 0 0 141 160 1 2
HES1 CCND3 0 0 113 174 1 1
HES1 ARNTL 0 0 65 159 1 1
HES1 OR1A1 0 0 165 165 1 1
HES1 GBP5 0 0 69 445 1 1
HES1 RAB1B 0 0 60 151 1 2
HES1 ATF3 0 0 134 285 1 2
HES1 FGF2 0 0 213 222 1 2
HES1 ZNF84 0 0 143 159 1 1
HES1 CSNK2A1 0 0 0 177 1 1
HES1 PROX1 0 0 92 320 1 1
HES1 CCND2 0 0 129 159 1 1
HES1 SPRY2 0 0 151 150 1 1
HES1 TLE2 270 600 342 824 1 1
HES1 ARX 0 0 194 225 1 1
HES1 NFKB2 0 0 54 165 1 1
HES1 PTCH1 0 0 201 230 1 1
HES1 GCG 0 0 167 180 1 1
HES1 AXIN2 0 0 114 179 1 1
HES1 FLI1 0 0 96 169 1 1
HES1 HOXB7 0 0 49 548 1 1
HES1 CCND1 0 0 322 371 1 2
HES1 MEIS1 0 0 0 157 1 1
HES1 UNCX 0 0 0 219 1 1
HES1 GATD3B 0 0 0 250 1 1
HES1 PSPC1 0 0 0 175 1 1
HES1 ABCG2 0 0 155 154 1 1
HES1 FGF5 0 0 54 188 1 1
HES1 ATR 0 900 0 900 1 2
HES1 DVL2 0 0 45 167 1 2
HES1 TOPBP1 0 900 0 900 1 1
HES1 GNLY 0 0 166 165 1 1
HES1 KAT2B 0 900 60 906 1 1
HES1 HEY1 675 900 768 976 1 1
HES1 SCRT1 0 0 0 164 1 1
HES1 OLIG2 0 0 143 208 1 1
HES1 PER1 0 0 126 246 1 1
HES1 HPGD 0 0 0 151 1 1
HES1 NKX2-5 0 0 123 274 1 1
HES1 TAL1 0 0 60 175 1 1
HES1 FANCI 0 900 0 903 1 1
HES1 SAP18 0 0 0 234 1 1
HES1 CCNE1 0 0 62 241 1 1
HES1 POU5F1 0 0 212 219 1 2
HES1 NUMBL 0 0 171 357 1 1
HES1 RPA1 0 900 0 900 1 1
HES1 FGF16 0 0 59 166 1 1
HES1 FOXA2 0 0 134 198 1 1
HES1 NR1D1 0 0 52 215 1 2
HES1 MYB 0 900 0 904 1 1
HES1 BCL2 0 0 134 152 1 2
HES1 MESP2 0 0 66 234 1 1
HES1 KCTD15 0 0 0 165 1 1
HES1 MDK 0 0 108 153 1 1
HES1 BLM 0 900 0 900 1 2
HES1 RAB14 0 0 0 173 1 1
HES1 CDX2 0 0 95 151 1 1
HES1 E2F3 0 0 117 174 1 1
HES1 COMMD3-BMI1 0 0 252 252 1 1
HES1 NFKBIA 0 0 112 159 1 2
HES1 ONECUT2 0 0 136 174 1 1
HES1 C21orf33 0 0 0 250 1 1
HES1 BMP4 0 0 245 286 1 1
HES1 TCF4 0 0 150 451 1 1
HES1 NKAP 0 0 90 152 1 1
HES1 MYOD1 0 0 141 268 1 1
HES1 BMPR1A 0 0 114 180 1 1
HES1 ID3 213 0 213 453 1 1
HES1 ASCL3 0 0 93 189 1 1
HES1 PTEN 0 0 450 464 1 2
HES1 STXBP5L 0 0 0 206 1 1
HES1 BARHL1 0 0 52 224 1 1
HES1 VEGFA 0 0 231 255 1 2
HES1 APITD1 0 900 0 900 1 1
HES1 RBPJ 270 900 721 980 1 1
HES1 PPARGC1B 0 0 74 167 1 1
HES1 SNAI1 0 0 218 262 1 1
HES1 EFNB2 0 0 73 151 1 1
HES1 GFAP 0 0 111 151 1 2
HES1 CCNL1 0 0 134 173 1 1
HES1 DYRK1B 0 0 92 154 1 1
HES1 TJP1 0 0 91 211 1 1
HES1 SOX10 0 0 150 284 1 1
HES1 NHLH1 0 0 85 199 1 1
HES1 SFRP1 0 0 108 177 1 1
HES1 CRB2 0 0 0 280 1 1
HES1 ZNF469 0 0 81 160 1 1
HES1 BAMBI 0 0 57 166 1 1
HES1 AXIN1 0 0 134 173 1 1
HES1 DNER 0 0 0 183 1 1
HES1 FANCL 270 900 440 955 1 1
HES1 NCAM1 0 0 91 241 1 1
HES1 DACH1 0 0 0 258 1 1
HES1 STMN1 0 0 66 166 1 1
HES1 PRKCA 213 0 53 224 1 1
HES1 NCAM2 0 0 0 200 1 1
HES1 ADAM17 0 0 210 269 1 1
HES1 WDR43 0 0 97 162 1 1
HES1 WDR11 0 0 0 173 1 1
HES1 UBC 270 0 0 276 1 2
HES1 TERT 0 0 88 182 1 2
HES1 HES4 0 0 149 233 1 1
HES1 GLI1 0 0 268 294 1 2
HES1 HSPB1 0 0 0 159 1 2
HES1 NKX2-1 0 0 134 219 1 1
HES1 GATA6 0 0 108 265 1 1
HES1 ATOH7 0 0 125 380 1 1
HES1 OTX2 0 0 113 197 1 1
HES1 YAP1 0 0 124 227 1 2
HES1 LGR5 0 0 270 298 1 1
HES1 WNT3A 0 0 183 220 1 2
HES1 MAML3 0 900 122 908 1 1
HES1 HMGB1 213 0 53 237 1 2
HES1 ESR1 0 0 124 158 1 2
HES1 EN1 0 0 52 211 1 1
HES1 GATA2 0 0 96 221 1 1
HES1 SMAD7 0 0 113 168 1 1
HES1 NPAS3 0 0 66 182 1 1
HES1 DLK1 0 0 112 247 1 1
HES1 TLE3 0 600 113 839 1 1
HES1 SIRT1 270 0 917 968 1 2
HES1 PSENEN 0 0 204 222 1 1
HES1 PTF1A 0 900 626 964 1 1
HES1 RFNG 0 0 151 172 1 1
HES1 ELAVL4 0 0 0 260 1 1
HES1 PCDHGA8 0 0 170 180 1 1
HES1 MET 0 0 129 180 1 2
HES1 EMC1 0 0 0 157 1 1
HES1 APH1A 111 0 95 169 1 1
HES1 ERRFI1 0 0 108 150 1 1
HES1 HES3 0 0 248 182 1 1
HES1 LFNG 0 0 156 318 1 1
HES1 RFC5 0 900 0 900 1 1
HES1 DLX5 0 0 54 181 1 1
HES1 GAS7 0 0 0 159 1 1
HES1 HEY2 270 650 459 778 1 1
HES1 FOS 0 0 157 156 1 2
HES1 KDM6B 0 0 44 200 1 1
HES1 RAD1 0 900 0 900 1 1
HES1 PDX1 0 0 282 302 1 1
HES1 ASCL1 0 0 459 801 1 1
HES1 DACH2 0 0 0 189 1 1
HES1 BTRC 0 0 53 160 1 1
HES1 SMIM12 0 0 92 191 1 1
HES1 HOXC8 0 0 0 316 1 1
HES1 MAMLD1 0 900 0 900 1 1
HES1 SYNCRIP 0 0 0 189 1 1
HES1 KRAS 0 0 130 190 1 2
HES1 FOXO1 0 0 171 189 1 2
HES1 FANCG 486 900 389 965 1 1
HES1 GSK3B 0 0 124 265 1 2
HES1 FANCF 486 900 398 966 1 1
HES1 FGF8 0 0 0 252 1 1
HES1 MCHR2 0 0 92 288 1 1
HES1 WNT2 0 0 63 275 1 1
HES1 EVX2 0 0 0 171 1 1
HES1 ABCD4 0 0 0 161 1 1
HES1 HDAC1 270 0 181 395 1 2
HES1 PHB2 0 0 384 384 1 1
HES1 WNT3 0 0 123 157 1 1
HES1 CRYAB 0 0 0 272 1 2
HES1 ELF3 0 0 108 151 1 1
HES1 CASP3 0 0 193 193 1 2
HES1 KIAA1244 0 0 0 169 1 1
HES1 STRA13 0 800 0 806 1 1
HES1 NFIB 0 0 74 162 1 1
HES1 IHH 0 0 143 182 1 1
HES1 NOTCH2 0 900 601 968 1 1
HES1 EBF3 0 0 0 173 1 1
HES1 OSR2 0 0 0 306 1 1
HES1 NR2C2 0 0 0 161 1 1
HES1 ENSG00000268643 0 0 0 174 1 1
HES1 INSM1 0 0 108 245 1 1
HES1 MYT1 0 0 95 234 1 1
HES1 BHLHA15 0 0 161 353 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0003677 Molecular Function DNA binding enables TAS
GO:0000981 Molecular Function DNA-binding transcription factor activity, RNA polymerase II-specific enables IBA
GO:0001227 Molecular Function DNA-binding transcription repressor activity, RNA polymerase II-specific enables ISS
GO:0070888 Molecular Function E-box binding enables IBA
GO:0070888 Molecular Function E-box binding enables ISS
GO:0043398 Molecular Function HLH domain binding enables IEA
GO:0008432 Molecular Function JUN kinase binding enables IEA
GO:0071820 Molecular Function N-box binding enables IBA
GO:0071820 Molecular Function N-box binding enables ISS
GO:0061629 Molecular Function RNA polymerase II-specific DNA-binding transcription factor binding enables ISS
GO:0003682 Molecular Function chromatin binding enables IEA
GO:0042826 Molecular Function histone deacetylase binding enables IPI
GO:0005515 Molecular Function protein binding enables IPI
GO:0042803 Molecular Function protein homodimerization activity enables ISS
GO:0044877 Molecular Function protein-containing complex binding enables IEA
GO:0051087 Molecular Function protein-folding chaperone binding enables IEA
GO:0043565 Molecular Function sequence-specific DNA binding enables ISS
GO:1990837 Molecular Function sequence-specific double-stranded DNA binding enables IDA
GO:0001222 Molecular Function transcription corepressor binding enables IEA
GO:0030509 Biological Process BMP signaling pathway involved_in IEA
GO:0021870 Biological Process Cajal-Retzius cell differentiation involved_in IEA
GO:0007219 Biological Process Notch signaling pathway involved_in IBA
GO:0007219 Biological Process Notch signaling pathway involved_in IDA
GO:0007219 Biological Process Notch signaling pathway involved_in IMP
GO:0072050 Biological Process S-shaped body morphogenesis involved_in IEA
GO:0042098 Biological Process T cell proliferation involved_in IEA
GO:0021984 Biological Process adenohypophysis development involved_in IEA
GO:0035881 Biological Process amacrine cell differentiation involved_in IEA
GO:0009952 Biological Process anterior/posterior pattern specification involved_in IBA
GO:0048844 Biological Process artery morphogenesis involved_in ISS
GO:0035910 Biological Process ascending aorta morphogenesis involved_in ISS
GO:0061309 Biological Process cardiac neural crest cell development involved in outflow tract morphogenesis involved_in IEA
GO:0007155 Biological Process cell adhesion involved_in IEA
GO:0001709 Biological Process cell fate determination involved_in IEA
GO:0048469 Biological Process cell maturation involved_in IEA
GO:0016477 Biological Process cell migration involved_in IEA
GO:0048667 Biological Process cell morphogenesis involved in neuron differentiation involved_in IEA
GO:0071398 Biological Process cellular response to fatty acid involved_in IEA
GO:0071347 Biological Process cellular response to interleukin-1 involved_in IEA
GO:1990090 Biological Process cellular response to nerve growth factor stimulus involved_in IEA
GO:0071356 Biological Process cellular response to tumor necrosis factor involved_in IEA
GO:0090102 Biological Process cochlea development involved_in IEA
GO:0072049 Biological Process comma-shaped body morphogenesis involved_in IEA
GO:0061009 Biological Process common bile duct development involved_in IEA
GO:0003143 Biological Process embryonic heart tube morphogenesis involved_in ISS
GO:0090162 Biological Process establishment of epithelial cell polarity involved_in IEA
GO:0021861 Biological Process forebrain radial glial cell differentiation involved_in ISS
GO:0072012 Biological Process glomerulus vasculature development involved_in IEA
GO:0021575 Biological Process hindbrain morphogenesis involved_in IEA
GO:0042491 Biological Process inner ear auditory receptor cell differentiation involved_in IEA
GO:0060122 Biological Process inner ear receptor cell stereocilium organization involved_in IEA
GO:0060716 Biological Process labyrinthine layer blood vessel development involved_in IEA
GO:0046331 Biological Process lateral inhibition involved_in IEA
GO:0001889 Biological Process liver development involved_in IEA
GO:0030324 Biological Process lung development involved_in IEA
GO:0072282 Biological Process metanephric nephron tubule morphogenesis involved_in IEA
GO:0030901 Biological Process midbrain development involved_in IEA
GO:0021555 Biological Process midbrain-hindbrain boundary morphogenesis involved_in IEA
GO:0043433 Biological Process negative regulation of DNA-binding transcription factor activity involved_in ISS
GO:0045892 Biological Process negative regulation of DNA-templated transcription involved_in IDA
GO:1902870 Biological Process negative regulation of amacrine cell differentiation involved_in IEA
GO:0090281 Biological Process negative regulation of calcium ion import involved_in IEA
GO:1905934 Biological Process negative regulation of cell fate determination involved_in IEA
GO:2000978 Biological Process negative regulation of forebrain neuron differentiation involved_in ISS
GO:0010629 Biological Process negative regulation of gene expression involved_in IEA
GO:0060253 Biological Process negative regulation of glial cell proliferation involved_in ISS
GO:0045608 Biological Process negative regulation of inner ear auditory receptor cell differentiation involved_in IEA
GO:0045665 Biological Process negative regulation of neuron differentiation involved_in IBA
GO:0010977 Biological Process negative regulation of neuron projection development involved_in IEA
GO:0048715 Biological Process negative regulation of oligodendrocyte differentiation involved_in ISS
GO:2000227 Biological Process negative regulation of pancreatic A cell differentiation involved_in IEA
GO:2000974 Biological Process negative regulation of pro-B cell differentiation involved_in IMP
GO:2000737 Biological Process negative regulation of stem cell differentiation involved_in IMP
GO:0061106 Biological Process negative regulation of stomach neuroendocrine cell differentiation involved_in IEA
GO:0000122 Biological Process negative regulation of transcription by RNA polymerase II involved_in IDA
GO:0007399 Biological Process nervous system development involved_in TAS
GO:0097150 Biological Process neuronal stem cell population maintenance involved_in IEP
GO:0021557 Biological Process oculomotor nerve development involved_in IEA
GO:0003151 Biological Process outflow tract morphogenesis involved_in ISS
GO:0003310 Biological Process pancreatic A cell differentiation involved_in IEA
GO:0061626 Biological Process pharyngeal arch artery morphogenesis involved_in ISS
GO:0030513 Biological Process positive regulation of BMP signaling pathway involved_in IEA
GO:0043388 Biological Process positive regulation of DNA binding involved_in ISS
GO:0045747 Biological Process positive regulation of Notch signaling pathway involved_in IEA
GO:0042102 Biological Process positive regulation of T cell proliferation involved_in IEA
GO:0048711 Biological Process positive regulation of astrocyte differentiation involved_in ISS
GO:0008284 Biological Process positive regulation of cell population proliferation involved_in ISS
GO:0010628 Biological Process positive regulation of gene expression involved_in IEA
GO:0045977 Biological Process positive regulation of mitotic cell cycle, embryonic involved_in ISS
GO:0046427 Biological Process positive regulation of receptor signaling pathway via JAK-STAT involved_in ISS
GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II involved_in ISS
GO:0042531 Biological Process positive regulation of tyrosine phosphorylation of STAT protein involved_in ISS
GO:0065003 Biological Process protein-containing complex assembly involved_in ISS
GO:0050678 Biological Process regulation of epithelial cell proliferation involved_in IEA
GO:0045598 Biological Process regulation of fat cell differentiation involved_in IEA
GO:0050767 Biological Process regulation of neurogenesis involved_in IBA
GO:0043254 Biological Process regulation of protein-containing complex assembly involved_in IEA
GO:0046425 Biological Process regulation of receptor signaling pathway via JAK-STAT involved_in ISS
GO:0003266 Biological Process regulation of secondary heart field cardioblast proliferation involved_in IEA
GO:0060164 Biological Process regulation of timing of neuron differentiation involved_in IEA
GO:0006357 Biological Process regulation of transcription by RNA polymerase II involved_in IBA
GO:0072141 Biological Process renal interstitial fibroblast development involved_in IEA
GO:0043279 Biological Process response to alkaloid involved_in IEA
GO:0014070 Biological Process response to organic cyclic compound involved_in IEA
GO:0097066 Biological Process response to thyroid hormone involved_in IEA
GO:0007224 Biological Process smoothened signaling pathway involved_in IEA
GO:0035019 Biological Process somatic stem cell population maintenance involved_in IEA
GO:0061102 Biological Process stomach neuroendocrine cell differentiation involved_in IEA
GO:0021537 Biological Process telencephalon development involved_in IEA
GO:0048538 Biological Process thymus development involved_in ISS
GO:0021558 Biological Process trochlear nerve development involved_in IEA
GO:0060675 Biological Process ureteric bud morphogenesis involved_in IEA
GO:0097084 Biological Process vascular associated smooth muscle cell development involved_in ISS
GO:0003281 Biological Process ventricular septum development involved_in ISS
GO:0060412 Biological Process ventricular septum morphogenesis involved_in ISS
GO:0000785 Cellular Component chromatin part_of IEA
GO:0005737 Cellular Component cytoplasm located_in IEA
GO:0016363 Cellular Component nuclear matrix located_in IEA
GO:0005654 Cellular Component nucleoplasm located_in IDA
GO:0005654 Cellular Component nucleoplasm located_in TAS
GO:0005634 Cellular Component nucleus is_active_in IBA
GO:0005634 Cellular Component nucleus located_in ISS
Pathways
Name DB ID
Developmental Biology Reactome R-HSA-1266738
Signaling by NOTCH Reactome R-HSA-157118
Signal Transduction Reactome R-HSA-162582
Disease Reactome R-HSA-1643685
Regulation of beta-cell development Reactome R-HSA-186712
Signaling by NOTCH1 Reactome R-HSA-1980143
Signaling by NOTCH2 Reactome R-HSA-1980145
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells Reactome R-HSA-210744
NOTCH1 Intracellular Domain Regulates Transcription Reactome R-HSA-2122947
Generic Transcription Pathway Reactome R-HSA-212436
NOTCH2 intracellular domain regulates transcription Reactome R-HSA-2197563
Signaling by NOTCH1 PEST Domain Mutants in Cancer Reactome R-HSA-2644602
Signaling by NOTCH1 in Cancer Reactome R-HSA-2644603
Constitutive Signaling by NOTCH1 PEST Domain Mutants Reactome R-HSA-2644606
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer Reactome R-HSA-2894858
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Reactome R-HSA-2894862
Diseases of signal transduction by growth factor receptors and second messengers Reactome R-HSA-5663202
RNA Polymerase II Transcription Reactome R-HSA-73857
Gene expression (Transcription) Reactome R-HSA-74160
Transcriptional regulation by RUNX3 Reactome R-HSA-8878159
Transcriptional regulation by RUNX2 Reactome R-HSA-8878166
RUNX2 regulates osteoblast differentiation Reactome R-HSA-8940973
RUNX2 regulates bone development Reactome R-HSA-8941326
RUNX3 regulates NOTCH signaling Reactome R-HSA-8941856
Signaling by NOTCH3 Reactome R-HSA-9012852
NOTCH3 Intracellular Domain Regulates Transcription Reactome R-HSA-9013508
Signaling by NOTCH4 Reactome R-HSA-9013694
NOTCH4 Intracellular Domain Regulates Transcription Reactome R-HSA-9013695
Neural crest differentiation (WP2064) WikiPathways WP2064_r117162
2q37 copy number variation syndrome (WP5224) WikiPathways WP5224_r122740
Breast cancer pathway (WP4262) WikiPathways WP4262_r123349
Notch signaling pathway (WP61) WikiPathways WP61_r120637
Influence of laminopathies on Wnt signaling (WP4844) WikiPathways WP4844_r123491
Sudden infant death syndrome (SIDS) susceptibility pathways (WP706) WikiPathways WP706_r117178
Notch signaling (WP268) WikiPathways WP268_r117167
Gene regulatory network modelling somitogenesis (WP2854) WikiPathways WP2854_r106431
Nuclear receptors meta-pathway (WP2882) WikiPathways WP2882_r120815
DYRK1A (WP5180) WikiPathways WP5180_r122423
MicroRNA for targeting cancer growth and vascularization in glioblastoma (WP3593) WikiPathways WP3593_r117786
PTF1A related regulatory pathway (WP4147) WikiPathways WP4147_r94394
22q11.2 copy number variation syndrome (WP4657) WikiPathways WP4657_r120007
Neurogenesis regulation in the olfactory epithelium (WP5265) WikiPathways WP5265_r123524
Overlap between signal transduction pathways contributing to LMNA laminopathies (WP4879) WikiPathways WP4879_r123415
Aryl hydrocarbon receptor pathway (WP2873) WikiPathways WP2873_r123110
Canonical and non-canonical Notch signaling (WP3845) WikiPathways WP3845_r123396
Transcripts
Accession Version MolecularType Name NCBI Comments
NM_005524 4 mRNA None NC_000003 Reference