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IL17A

interleukin 17A
General Information
Name interleukin 17A
Alias
  • interleukin-17A
  • cytotoxic T-lymphocyte-associated antigen 8
  • cytotoxic T-lymphocyte-associated protein 8
  • interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
  • interleukin-17
Gene_family Interleukins
organism Homo sapiens
entrez_id 3605
location 6p12.2
transcript_count 1
exon_count 3
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez This gene is a member of the IL-17 receptor family which includes five members (IL-17RA-E) and the encoded protein is a proinflammatory cytokine produced by activated T cells. IL-17A-mediated downstream pathways induce the production of inflammatory molecules, chemokines, antimicrobial peptides, and remodeling proteins. The encoded protein elicits crucial impacts on host defense, cell trafficking, immune modulation, and tissue repair, with a key role in the induction of innate immune defenses. This cytokine stimulates non-hematopoietic cells and promotes chemokine production thereby attracting myeloid cells to inflammatory sites. This cytokine also regulates the activities of NF-kappaB and mitogen-activated protein kinases and can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). IL-17A plays a pivotal role in various infectious diseases, inflammatory and autoimmune disorders, and cancer. High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. The lung damage induced by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is to a large extent, a result of the inflammatory response promoted by cytokines such as IL17A. [provided by RefSeq, Sep 2020]
    Stringdb Interleukin-17A; Ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines; Belongs to the IL-17 family
    nextProt Effector cytokine of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tissue integrity (PubMed:24120361). Signals via IL17RA-IL17RC heterodimeric receptor complex, triggering homotypic interaction of IL17RA and IL17RC chains with TRAF3IP2 adapter. This leads to downstream TRAF6-mediated activation of NF-kappa-B and MAPkinase pathways ultimately resulting in transcriptional activation of cytokines, chemokines, antimicrobial peptides and matrix metalloproteinases, with potential strong immune inflammation (PubMed:19825828, PubMed:21350122, PubMed:17911633, PubMed:18684971, PubMed:8676080, PubMed:24120361). Plays an important role in connecting T cell-mediated adaptive immunity and acute inflammatory response to destroy extracellular bacteria and fungi. As a signature effector cytokine of T-helper 17 cells (Th17), primarily induces neutrophil activation and recruitment at infection and inflammatory sites (By similarity). In airway epithelium, mediates neutrophil chemotaxis via induction of CXCL1 and CXCL5 chemokines (By similarity). In secondary lymphoid organs, contributes to germinal center formation by regulating the chemotactic response of B cells to CXCL12 and CXCL13, enhancing retention of B cells within the germinal centers, B cell somatic hypermutation rate and selection toward plasma cells (By similarity). Effector cytokine of a subset of gamma-delta T cells that functions as part of an inflammatory circuit downstream IL1B, TLR2 and IL23A-IL12B to promote neutrophil recruitment for efficient bacterial clearance (By similarity). Effector cytokine of innate immune cells including invariant natural killer cell (iNKT) and group 3 innate lymphoid cells that mediate initial neutrophilic inflammation (By similarity). Involved in the maintenance of the integrity of epithelial barriers during homeostasis and pathogen infection (PubMed:21350122). Upon acute injury, has a direct role in epithelial barrier formation by regulating OCLN localization and tight junction biogenesis (By similarity). As part of the mucosal immune response induced by commensal bacteria, enhances host's ability to resist pathogenic bacterial and fungal infections by promoting neutrophil recruitment and antimicrobial peptides release (By similarity). In synergy with IL17F, mediates the production of antimicrobial beta-defensins DEFB1, DEFB103A, and DEFB104A by mucosal epithelial cells, limiting the entry of microbes through the epithelial barriers (By similarity). Involved in antiviral host defense through various mechanisms (By similarity). Enhances immunity against West Nile virus by promoting T cell cytotoxicity (By similarity). May play a beneficial role in influenza A virus (H5N1) infection by enhancing B cell recruitment and immune response in the lung (By similarity). Contributes to influenza A virus (H1N1) clearance by driving the differentiation of B-1a B cells, providing for production of virus-specific IgM antibodies at first line of host defense (By similarity).
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
IL17A BioGRID ATP1A3 GeneID BioGRID Affinity Capture-MS
IL17A BioGRID LONP2 GeneID BioGRID Affinity Capture-MS
IL17A BioGRID TXNDC15 GeneID BioGRID Affinity Capture-MS
IL17A BioGRID DPP8 GeneID BioGRID Affinity Capture-MS
IL17A BioGRID IL17RA GeneID BioGRID Affinity Capture-MS
IL17A BioGRID IL2 GeneID BioGRID Affinity Capture-MS
IL17A BioGRID KCNIP4 GeneID BioGRID Two-hybrid
IL17A BioGRID DPH2 GeneID BioGRID Two-hybrid
IL17A BioGRID TRAF3IP2 GeneID BioGRID Affinity Capture-Western
IL17A BioGRID TRAF6 GeneID BioGRID Affinity Capture-Western
IL17A Protein IL17RA GeneID HPRD
IL17A Protein IL17A GeneID HPRD
IL17A BioGRID IL17A GeneID BioGRID Reconstituted Complex
StringDB
A B experiments database textmining combined score hadb nhadb
IL17A DUOXA2 0 0 113 155 1 1
IL17A CARD9 0 0 609 609 1 1
IL17A FGF7 0 0 370 374 1 1
IL17A HK2 0 0 162 183 1 2
IL17A TRAF1 0 0 292 292 1 1
IL17A CAMP 0 0 606 606 1 2
IL17A CSF3 0 0 840 851 1 1
IL17A P2RX4 0 0 193 224 1 1
IL17A NCOR2 0 0 208 208 1 1
IL17A IRAK1 0 0 459 459 1 1
IL17A TXK 0 0 181 181 1 1
IL17A LMNA 0 0 230 229 1 2
IL17A MUC5B 0 0 420 428 1 1
IL17A HLA-DQB2 0 0 71 384 1 1
IL17A RAF1 0 0 108 159 1 2
IL17A ORAI1 0 0 153 152 1 1
IL17A PLP1 0 0 244 243 1 1
IL17A LCP2 0 0 255 254 1 1
IL17A ADAM33 0 0 193 193 1 1
IL17A CD200R1 0 0 309 309 1 1
IL17A TNFRSF11B 0 0 562 562 1 1
IL17A PAEP 0 0 142 173 1 1
IL17A NFKBIZ 0 0 506 506 1 1
IL17A HDAC2 0 0 235 246 1 1
IL17A MAP3K7 0 0 259 258 1 2
IL17A KRT10 0 0 270 270 1 1
IL17A DDIT3 0 0 181 541 1 2
IL17A SELPLG 0 0 326 325 1 1
IL17A KIR3DL2 0 0 325 325 1 1
IL17A NR1H2 0 0 307 307 1 1
IL17A S100A1 0 0 281 282 1 1
IL17A IL20RA 0 0 294 296 1 1
IL17A CFTR 0 0 310 309 1 2
IL17A IVL 0 0 314 313 1 1
IL17A RASGRP1 0 0 167 167 1 1
IL17A SCN10A 0 0 150 173 1 1
IL17A TP53 0 0 455 466 1 2
IL17A LCN2 0 900 602 958 1 1
IL17A PSCA 0 0 113 165 1 1
IL17A SLC26A4 0 0 150 241 1 1
IL17A KLRC1 0 0 403 403 1 1
IL17A DCN 0 0 181 181 1 2
IL17A ALOX15 0 0 243 242 1 1
IL17A IRF9 0 0 242 241 1 1
IL17A STEAP4 0 0 155 154 1 1
IL17A TGM2 0 0 293 293 1 2
IL17A CFLAR 0 0 240 239 1 2
IL17A EGFR 0 0 409 408 1 2
IL17A HIST1H4I 0 0 155 202 1 1
IL17A PSTPIP1 0 0 163 163 1 1
IL17A MYD88 0 0 682 696 1 2
IL17A DEFB103A 0 0 507 507 1 1
IL17A TOR1A 0 0 334 334 1 1
IL17A CD2BP2 0 0 155 154 1 1
IL17A ADORA3 0 0 298 298 1 1
IL17A TNFRSF4 0 0 566 569 1 1
IL17A FADD 0 0 218 218 1 2
IL17A ZNF341 0 0 150 164 1 1
IL17A ESX1 0 0 161 172 1 1
IL17A TSLP 0 0 690 692 1 1
IL17A LAMP1 0 0 460 472 1 2
IL17A SLC2A1 0 0 262 262 1 2
IL17A MMP15 0 0 62 317 1 1
IL17A GATA3 0 0 800 813 1 1
IL17A KRT5 0 0 182 181 1 1
IL17A CCL25 0 0 455 456 1 1
IL17A MUC5AC 0 0 556 562 1 1
IL17A SERPINH1 0 0 442 442 1 1
IL17A SOX4 0 0 193 193 1 1
IL17A MICA 0 0 391 390 1 1
IL17A PCSK5 0 0 276 276 1 1
IL17A STAT3 0 900 804 994 1 2
IL17A GDNF 0 0 234 234 1 2
IL17A EZH2 0 0 194 194 1 2
IL17A IDO2 0 0 236 236 1 1
IL17A ITGB8 0 0 139 157 1 1
IL17A IFNA2 0 0 458 457 1 1
IL17A HBEGF 0 0 405 405 1 1
IL17A DEFA5 0 0 247 264 1 1
IL17A CD55 0 0 284 284 1 1
IL17A EIF2AK4 0 0 217 217 1 2
IL17A TGFA 0 0 230 229 1 1
IL17A PTPN22 0 0 401 400 1 1
IL17A APAF1 0 0 123 163 1 2
IL17A CDH2 0 0 183 183 1 1
IL17A PTX3 0 0 369 369 1 1
IL17A REG3G 0 0 413 429 1 1
IL17A FCER2 0 0 170 169 1 1
IL17A MREG 0 0 134 165 1 1
IL17A HLA-DQB1 0 0 155 338 1 1
IL17A NLRC5 0 0 151 150 1 1
IL17A JAK2 0 0 558 558 1 2
IL17A COL2A1 0 0 145 165 1 2
IL17A GHRL 0 0 202 202 1 1
IL17A TSC22D3 0 0 284 284 1 1
IL17A NR4A1 0 0 281 281 1 2
IL17A SFTPC 0 0 213 213 1 1
IL17A IL20RB 0 0 261 277 1 1
IL17A BRD4 0 0 142 218 1 2
IL17A CLU 0 0 166 165 1 2
IL17A CCL26 0 0 500 499 1 1
IL17A CYBA 0 0 203 203 1 1
IL17A SRSF1 0 0 202 202 1 1
IL17A CD101 0 0 213 213 1 1
IL17A FLG2 0 0 149 168 1 1
IL17A APOH 0 0 123 155 1 1
IL17A FOLR4 0 0 218 218 1 1
IL17A NTAN1 0 0 244 243 1 1
IL17A GNAQ 0 0 161 161 1 1
IL17A SEMA6A 0 0 123 163 1 1
IL17A ADORA1 0 0 263 263 1 1
IL17A MEFV 0 0 401 400 1 1
IL17A RICTOR 0 0 194 194 1 2
IL17A NOG 0 0 171 171 1 1
IL17A TAB1 0 0 180 179 1 1
IL17A TRAF2 0 0 194 208 1 2
IL17A MX1 0 0 377 377 1 1
IL17A IL2RA 0 0 652 729 1 1
IL17A MMP17 0 0 0 302 1 1
IL17A ACP5 0 0 459 459 1 1
IL17A ACACA 0 0 157 156 1 1
IL17A CLEC11A 0 0 370 370 1 1
IL17A IL27RA 0 0 517 517 1 1
IL17A CEACAM5 0 0 249 248 1 1
IL17A NR2F6 0 0 187 187 1 1
IL17A DCD 0 0 170 169 1 1
IL17A NR0B2 0 0 171 171 1 1
IL17A IFNA1 0 0 719 719 1 1
IL17A WNT5A 0 0 216 222 1 2
IL17A IL18 0 0 805 826 1 2
IL17A PPIG 0 0 204 204 1 1
IL17A IL1R1 0 0 690 690 1 1
IL17A IFITM3 0 0 151 150 1 1
IL17A ITGAE 0 0 701 713 1 1
IL17A MYC 0 0 394 394 1 2
IL17A S100A7 0 0 563 563 1 1
IL17A IRGM 0 0 324 323 1 2
IL17A IL15 0 0 806 835 1 1
IL17A TREM1 0 0 422 422 1 1
IL17A PPARGC1A 0 0 181 181 1 2
IL17A TAGAP 0 0 165 165 1 1
IL17A TNFRSF6B 0 0 255 254 1 1
IL17A TPH1 0 0 217 217 1 1
IL17A PI3 0 0 293 293 1 2
IL17A ADAM10 0 0 210 210 1 1
IL17A IL36G 0 0 413 448 1 1
IL17A TAB2 0 0 287 286 1 2
IL17A IGF1R 0 0 175 176 1 2
IL17A CD84 0 0 211 211 1 1
IL17A SDHC 0 0 219 219 1 1
IL17A ITGAD 0 0 81 272 1 1
IL17A SLC30A10 0 0 161 161 1 1
IL17A RPS19 0 0 294 294 1 1
IL17A BTN3A1 0 0 253 252 1 1
IL17A TLR1 0 0 558 587 1 1
IL17A NFE2L2 0 0 242 241 1 2
IL17A BACH2 0 0 244 243 1 1
IL17A LILRB1 0 0 218 218 1 1
IL17A CLEC1B 0 0 171 171 1 1
IL17A TCF3 0 0 286 286 1 1
IL17A IKZF3 0 0 287 298 1 1
IL17A OSM 0 900 609 959 1 1
IL17A C5 0 0 206 255 1 1
IL17A MAP2K1 0 0 289 288 1 1
IL17A FUT4 0 0 363 363 1 1
IL17A MAP3K8 0 0 245 244 1 1
IL17A F2RL1 0 0 95 157 1 1
IL17A CH25H 0 0 163 163 1 1
IL17A CCL21 0 0 525 533 1 1
IL17A NLRP12 0 0 207 207 1 1
IL17A PDGFB 0 0 244 243 1 2
IL17A CD80 0 0 710 728 1 2
IL17A STK11 0 0 144 150 1 2
IL17A FURIN 0 0 202 202 1 1
IL17A AREG 0 0 466 469 1 1
IL17A OASL 0 0 181 181 1 1
IL17A TDO2 0 0 232 231 1 1
IL17A S1PR2 0 0 194 194 1 1
IL17A CLEC4A 0 0 193 193 1 1
IL17A CIDEB 0 0 155 154 1 1
IL17A ALOX12 0 0 155 154 1 1
IL17A SLC26A9 0 0 54 158 1 1
IL17A DYNLT1 0 0 151 150 1 2
IL17A HIST1H4L 0 0 155 202 1 1
IL17A TNFRSF12A 0 0 232 231 1 1
IL17A SMAD4 0 0 310 309 1 2
IL17A OAS3 0 0 167 167 1 1
IL17A SPARCL1 0 0 108 235 1 1
IL17A CHI3L1 0 0 391 390 1 1
IL17A LY75 0 0 390 390 1 1
IL17A NELFCD 0 0 700 700 1 1
IL17A LAG3 0 0 558 561 1 1
IL17A ACTA1 0 0 113 202 1 1
IL17A IL1RL2 0 0 517 517 1 1
IL17A SFTPA2 0 0 181 181 1 1
IL17A KCNN3 0 0 390 390 1 1
IL17A IL17RC 0 800 988 998 1 1
IL17A HECA 0 0 141 185 1 1
IL17A IL12A 0 0 174 533 1 1
IL17A TNFRSF13B 0 0 325 325 1 1
IL17A LGALS9 0 0 416 436 1 1
IL17A PTGES2 0 0 170 169 1 1
IL17A LCE3B 0 0 171 171 1 1
IL17A HSPD1 0 0 364 364 1 1
IL17A ANXA5 0 0 556 559 1 2
IL17A FGF21 0 0 147 301 1 2
IL17A OSMR 0 0 182 181 1 1
IL17A TNFSF13 0 0 241 240 1 1
IL17A PTGER1 0 0 195 195 1 1
IL17A TNFSF18 0 0 288 288 1 1
IL17A C17orf99 0 0 250 250 1 1
IL17A EPO 0 0 324 323 1 2
IL17A TNFSF9 0 0 294 294 1 1
IL17A C5AR1 0 0 464 463 1 1
IL17A CXCL13 0 0 617 630 1 1
IL17A CLEC4D 0 0 268 268 1 1
IL17A IL4R 0 0 517 517 1 1
IL17A TTC4 0 0 325 325 1 1
IL17A HLA-DPB1 0 0 143 167 1 1
IL17A CREBBP 0 0 151 345 1 1
IL17A HCAR2 0 0 322 334 1 1
IL17A GPR32 0 0 154 153 1 1
IL17A CCL13 0 0 427 431 1 1
IL17A TECTA 0 0 0 208 1 1
IL17A SDHB 0 0 167 167 1 1
IL17A BCL11B 0 0 284 295 1 1
IL17A HAVCR1 0 0 218 218 1 1
IL17A IGJ 0 0 167 167 1 1
IL17A TNFRSF17 0 0 203 203 1 1
IL17A PLCG2 0 0 211 211 1 1
IL17A TGFB3 0 0 458 457 1 1
IL17A CCL5 0 0 806 839 1 2
IL17A HCST 0 0 160 159 1 1
IL17A CREB1 0 0 390 390 1 2
IL17A GSDMD 0 0 181 181 1 2
IL17A PCSK7 0 0 261 261 1 1
IL17A APC 0 0 184 183 1 1
IL17A IFNG 0 0 826 902 1 2
IL17A BIRC2 0 0 181 181 1 1
IL17A IL2RB 0 0 505 538 1 1
IL17A CYP1A1 0 0 310 309 1 2
IL17A TNFRSF25 0 0 450 450 1 1
IL17A EGR3 0 0 244 256 1 1
IL17A DNASE1 0 0 229 228 1 1
IL17A GAPDH 0 0 681 690 1 2
IL17A DUSP5 0 0 180 179 1 1
IL17A TRIAP1 0 0 161 161 1 1
IL17A TLR4 0 0 766 774 1 2
IL17A SMAD2 0 0 425 424 1 2
IL17A EMR1 0 0 60 549 1 1
IL17A B3GAT1 0 0 403 403 1 1
IL17A IL9R 0 0 315 332 1 1
IL17A ENO1 0 0 244 243 1 1
IL17A CD22 0 0 292 294 1 1
IL17A HIST4H4 0 0 155 202 1 1
IL17A CX3CL1 0 0 607 609 1 1
IL17A CD1A 0 0 459 463 1 1
IL17A NOS2 0 0 504 526 1 2
IL17A CPA4 0 0 135 153 1 1
IL17A MAP2K7 0 0 322 321 1 1
IL17A CD14 0 0 116 415 1 1
IL17A CD83 0 0 519 527 1 1
IL17A OAS2 0 0 181 181 1 1
IL17A HAMP 0 0 264 264 1 1
IL17A JAG2 0 0 203 203 1 1
IL17A APOA1 0 0 264 264 1 1
IL17A TNFSF15 0 0 493 518 1 1
IL17A CLEC7A 0 0 681 681 1 1
IL17A TLR10 0 0 378 547 1 1
IL17A MMP20 0 0 0 302 1 1
IL17A TPO 0 0 235 235 1 1
IL17A ZAP70 0 0 463 463 1 1
IL17A STAT4 0 0 608 691 1 1
IL17A TAB3 0 0 244 243 1 1
IL17A ITGA4 0 0 503 503 1 1
IL17A ACKR4 0 0 469 469 1 1
IL17A KITLG 0 0 421 420 1 1
IL17A ALDH1A2 0 0 242 241 1 1
IL17A CALCR 0 0 253 252 1 1
IL17A RELA 0 0 459 460 1 2
IL17A ENSG00000026036 0 0 258 258 1 1
IL17A ANAPC5 0 0 442 442 1 1
IL17A BCL2L1 0 0 405 415 1 2
IL17A AOC3 0 0 688 688 1 1
IL17A CCL4L1 0 0 801 822 1 1
IL17A RORA 0 0 504 577 1 1
IL17A ACKR3 0 0 170 169 1 1
IL17A KCNIP4 298 0 0 298 1 1
IL17A CD7 0 0 453 453 1 1
IL17A C1R 0 0 205 205 1 1
IL17A NFKB1 0 0 336 370 1 2
IL17A LAMC2 0 0 165 165 1 1
IL17A DNMT3A 270 0 150 352 1 2
IL17A TCHH 0 0 286 286 1 1
IL17A APP 0 0 296 296 1 2
IL17A EGR1 0 0 241 253 1 2
IL17A S1PR3 0 0 232 231 1 1
IL17A TRPV1 0 0 292 298 1 2
IL17A FCRL3 0 0 170 169 1 1
IL17A CTNNB1 0 0 553 553 1 2
IL17A FCGR3A 0 0 654 654 1 1
IL17A HRAS 0 0 325 336 1 2
IL17A SOCS7 0 0 251 250 1 1
IL17A VIPR2 0 0 155 154 1 1
IL17A TNFRSF1B 0 0 493 493 1 1
IL17A IKBKE 0 0 246 245 1 1
IL17A ERAP1 0 0 391 390 1 1
IL17A B7RP1 0 0 556 565 1 1
IL17A KRT17 0 0 180 179 1 1
IL17A PLA2G4A 0 0 162 161 1 1
IL17A CXCR2 0 0 602 602 1 1
IL17A WNT2B 0 0 96 179 1 1
IL17A C3AR1 0 0 365 365 1 1
IL17A MYOM2 0 0 213 213 1 1
IL17A NR1H3 0 0 108 169 1 1
IL17A IL1B 0 0 938 949 1 2
IL17A FAT1 0 0 142 175 1 1
IL17A OAS1 0 0 202 202 1 1
IL17A CYP27B1 0 0 335 335 1 1
IL17A HIF1A 0 0 518 588 1 2
IL17A EDN1 0 0 391 390 1 1
IL17A POSTN 0 0 361 361 1 1
IL17A TRAF5 0 0 600 604 1 1
IL17A NCR1 0 0 603 606 1 1
IL17A SLC1A7 0 0 171 171 1 1
IL17A KLK3 0 0 184 183 1 1
IL17A NFKBID 0 0 186 222 1 1
IL17A CTSL 0 0 156 155 1 2
IL17A IL6R 0 0 600 623 1 1
IL17A MAPK13 0 0 122 172 1 1
IL17A ENSG00000268500 0 0 109 304 1 1
IL17A NCR3 0 0 325 325 1 1
IL17A CXCL8 0 0 870 891 1 2
IL17A LYVE1 0 0 183 183 1 1
IL17A LYZ 0 0 155 215 1 1
IL17A CTRL 0 0 236 236 1 2
IL17A MOG 0 0 760 783 1 1
IL17A PIRT 0 0 0 155 1 1
IL17A CXCL14 0 0 218 218 1 1
IL17A RBP3 0 0 561 571 1 1
IL17A F11R 0 0 235 235 1 1
IL17A IL6 0 900 915 994 1 2
IL17A BTLA 0 0 391 390 1 1
IL17A IL3RA 0 0 426 426 1 1
IL17A ACAN 0 0 374 374 1 1
IL17A MPO 0 0 662 667 1 2
IL17A TNFRSF1A 0 0 588 588 1 1
IL17A GZMB 0 0 684 691 1 1
IL17A RPL32 0 0 158 157 1 1
IL17A IL17D 0 0 681 289 1 1
IL17A OCLN 0 0 503 503 1 1
IL17A BRD2 0 0 144 240 1 1
IL17A STAT1 0 0 688 741 1 2
IL17A KCNA5 0 0 0 363 1 1
IL17A SOCS5 0 0 272 272 1 1
IL17A DEFB1 0 0 390 390 1 1
IL17A BATF2 0 0 123 165 1 1
IL17A LMLN 0 0 161 183 1 1
IL17A NOTCH1 0 0 458 457 1 2
IL17A PTPN13 0 0 103 193 1 1
IL17A MMP1 0 900 495 947 1 1
IL17A ENTPD1 0 0 609 611 1 1
IL17A CD40LG 0 0 751 766 1 1
IL17A PTGS1 0 0 195 195 1 1
IL17A TRAF4 0 0 345 345 1 1
IL17A CD177 0 0 224 224 1 1
IL17A FGF13 0 0 406 406 1 1
IL17A CTAG1A 0 0 247 246 1 1
IL17A HLA-G 0 0 342 342 1 1
IL17A CXCR4 0 0 561 561 1 2
IL17A HIST1H4F 0 0 155 202 1 1
IL17A CYR61 0 0 167 167 1 1
IL17A TIMP4 0 0 166 165 1 1
IL17A POTEF 0 0 341 398 1 1
IL17A XPNPEP1 0 0 212 212 1 1
IL17A CD163 0 0 517 517 1 1
IL17A SORT1 0 0 230 230 1 1
IL17A SAA1 0 900 416 939 1 1
IL17A C4A 0 0 244 243 1 1
IL17A MTOR 0 0 463 463 1 2
IL17A NLRP1 0 0 358 358 1 1
IL17A SPINK5 0 0 204 204 1 1
IL17A RPL13A 0 0 170 169 1 1
IL17A CSF2RA 0 0 241 240 1 1
IL17A SPP1 0 0 502 502 1 2
IL17A TNFRSF14 0 0 341 341 1 1
IL17A GSR 0 0 167 167 1 1
IL17A GNRH1 0 0 160 159 1 1
IL17A CD1C 0 0 560 582 1 1
IL17A EPCAM 0 0 342 342 1 2
IL17A IFNAR2 0 0 358 358 1 1
IL17A FGL2 0 0 245 244 1 1
IL17A AR 0 0 171 171 1 2
IL17A RHOA 0 0 310 309 1 2
IL17A PARP1 0 0 167 167 1 2
IL17A TLR5 0 0 601 601 1 1
IL17A CRLF2 0 0 390 390 1 1
IL17A CD3D 0 0 233 232 1 1
IL17A KLRK1 0 0 561 577 1 1
IL17A PLA2G1B 0 0 286 317 1 1
IL17A TNNI3 0 0 170 169 1 1
IL17A PYY 0 0 124 178 1 1
IL17A GPR29 0 0 827 862 1 1
IL17A ZNF740 0 0 261 273 1 1
IL17A FGF4 0 0 53 209 1 1
IL17A TIMP1 0 900 523 950 1 1
IL17A IL36A 0 0 392 430 1 1
IL17A CCL18 0 0 455 480 1 1
IL17A CXCL12 0 0 604 604 1 2
IL17A NCKAP5L 0 0 66 169 1 1
IL17A ITGAV 0 0 209 209 1 1
IL17A BCL10 0 0 342 342 1 1
IL17A SEMA4A 0 0 193 193 1 1
IL17A CYP2R1 0 0 202 202 1 1
IL17A ZBTB7B 0 0 376 386 1 1
IL17A SOST 0 0 294 294 1 1
IL17A CD160 0 0 265 265 1 1
IL17A PTPRC 0 0 759 775 1 1
IL17A ESR2 0 0 235 235 1 1
IL17A CXCR1 0 0 456 493 1 1
IL17A SOX9 0 0 188 188 1 1
IL17A MS4A1 0 0 143 327 1 1
IL17A ZNF683 0 0 193 193 1 1
IL17A IL22 0 0 917 938 1 1
IL17A ZEB1 0 0 162 161 1 2
IL17A CD24 0 0 460 459 1 2
IL17A CTAG1B 0 0 246 245 1 1
IL17A UNC93B1 0 0 186 186 1 1
IL17A CRTAM 0 0 309 309 1 1
IL17A ADORA2A 0 0 317 325 1 1
IL17A PTPRN 0 0 170 169 1 1
IL17A ICAM1 0 0 681 686 1 2
IL17A PTGER2 0 0 123 184 1 1
IL17A LY9 0 0 217 217 1 1
IL17A FOSL1 0 0 193 231 1 1
IL17A IL3 0 0 703 724 1 1
IL17A LTB 0 0 326 368 1 1
IL17A LBP 0 900 241 920 1 1
IL17A HSP90AA1 0 0 296 296 1 2
IL17A MBL2 0 0 335 335 1 1
IL17A SP7 0 0 233 259 1 1
IL17A IL21 0 0 559 800 1 1
IL17A HPGDS 0 0 216 216 1 1
IL17A SLC9A3 0 0 158 157 1 1
IL17A SOX2 0 0 175 175 1 2
IL17A CLEC2D 0 0 297 354 1 1
IL17A PTGDR2 0 0 518 518 1 1
IL17A CEBPA 0 0 261 261 1 1
IL17A SPDYA 0 0 98 154 1 1
IL17A PSEN1 0 0 234 234 1 2
IL17A SLAMF6 0 0 293 293 1 1
IL17A ATF2 0 0 109 151 1 1
IL17A CRP 0 0 702 702 1 2
IL17A INS 0 0 558 569 1 2
IL17A SELP 0 0 469 469 1 1
IL17A CCL15 0 0 324 323 1 1
IL17A CLDN5 0 0 240 239 1 1
IL17A GAS6 0 0 180 179 1 1
IL17A ACTB 0 0 654 683 1 2
IL17A ADAMTS5 0 0 261 311 1 1
IL17A ENSG00000258555 0 0 303 311 1 1
IL17A EMR2 0 0 82 237 1 1
IL17A IL17B 0 0 701 303 1 1
IL17A EPRS 0 0 214 214 1 1
IL17A CD8B 0 0 234 234 1 1
IL17A FPR2 0 0 293 293 1 1
IL17A SELL 0 0 739 758 1 1
IL17A CD40 0 0 710 729 1 2
IL17A FGF1 0 0 181 181 1 1
IL17A ITGB7 0 0 325 325 1 1
IL17A C1S 0 0 171 171 1 1
IL17A DNMT1 0 0 261 261 1 2
IL17A STUB1 0 0 194 194 1 2
IL17A B2M 0 0 459 470 1 1
IL17A MMP9 0 900 661 964 1 2
IL17A PAX5 0 0 164 163 1 1
IL17A KEAP1 0 0 177 177 1 2
IL17A MAPK3 0 0 517 517 1 2
IL17A PROM1 0 0 234 234 1 2
IL17A ANGPT1 0 0 235 235 1 1
IL17A ABCG1 0 0 213 213 1 2
IL17A THY1 0 0 557 600 1 1
IL17A KIR3DL3 0 0 167 167 1 1
IL17A JUNB 0 0 261 261 1 1
IL17A HIST1H4J 0 0 155 202 1 1
IL17A MICB 0 0 270 270 1 1
IL17A FCGR2B 0 0 612 637 1 1
IL17A DTX1 0 0 108 161 1 1
IL17A CCR3 0 0 507 529 1 1
IL17A CASP1 0 0 609 632 1 2
IL17A NOS1 0 0 169 175 1 1
IL17A PVR 0 0 209 209 1 1
IL17A CXCL6 0 0 403 536 1 1
IL17A SNCA 0 0 183 183 1 2
IL17A CD27 0 0 654 658 1 1
IL17A CD74 0 0 253 252 1 1
IL17A DNTT 0 0 261 261 1 1
IL17A DEFB104A 0 0 241 240 1 1
IL17A MAP2K3 0 0 216 216 1 1
IL17A GPR83 0 0 152 151 1 1
IL17A PIK3CG 0 0 258 258 1 1
IL17A JAK3 0 0 505 505 1 1
IL17A ZBTB16 0 0 469 477 1 1
IL17A PADI4 0 0 325 325 1 1
IL17A FFAR2 0 0 470 470 1 1
IL17A COL18A1 0 0 203 203 1 1
IL17A HSPA1A 0 0 157 180 1 1
IL17A AIF1 0 0 451 451 1 2
IL17A ORMDL3 0 0 170 169 1 2
IL17A ZFP36 0 0 284 284 1 1
IL17A HLA-DRB1 0 0 420 437 1 1
IL17A TNFSF10 0 0 394 394 1 2
IL17A CAV1 0 0 181 181 1 2
IL17A BRD3 0 0 105 194 1 1
IL17A CYP19A1 0 0 167 167 1 2
IL17A ENSG00000173366 0 0 681 700 1 1
IL17A SERPINA1 0 0 298 298 1 2
IL17A CCL24 0 0 517 517 1 1
IL17A SIGLEC1 0 0 280 280 1 1
IL17A S1PR4 0 0 229 228 1 1
IL17A LONP2 376 0 0 376 1 1
IL17A CDH17 0 0 194 194 1 1
IL17A IL10RA 0 0 559 562 1 1
IL17A GZMA 0 0 467 467 1 1
IL17A DLL4 0 0 294 294 1 1
IL17A RC3H2 0 0 209 209 1 1
IL17A NPPB 0 0 113 168 1 1
IL17A SERPINB2 0 0 150 603 1 1
IL17A BCL2L11 0 0 320 320 1 2
IL17A ITGAL 0 0 466 465 1 1
IL17A MAFB 0 0 74 168 1 1
IL17A TMEM173 0 0 157 156 1 1
IL17A FUT2 0 0 261 261 1 1
IL17A TYK2 0 0 559 559 1 1
IL17A PLCG1 0 0 260 260 1 1
IL17A NAALADL1 0 0 470 470 1 1
IL17A ARID5A 0 0 193 193 1 1
IL17A BATF 0 0 600 658 1 1
IL17A JUN 0 0 550 553 1 2
IL17A TFF3 0 0 244 243 1 1
IL17A IL17RA 922 800 989 999 1 1
IL17A CCRL2 0 0 806 806 1 1
IL17A CLEC6A 0 0 519 519 1 1
IL17A JAG1 0 0 294 294 1 1
IL17A IFNK 0 0 125 232 1 1
IL17A LCK 0 0 468 468 1 1
IL17A MSLN 0 0 213 213 1 1
IL17A FYN 0 0 250 250 1 1
IL17A ASCL2 0 0 202 207 1 1
IL17A CYSLTR1 0 0 266 266 1 1
IL17A GRN 0 0 180 179 1 1
IL17A PVRL2 0 0 150 169 1 1
IL17A GRB2 0 0 162 161 1 1
IL17A AZGP1 0 0 129 189 1 1
IL17A TICAM1 0 0 261 261 1 2
IL17A DCSTAMP 0 0 205 205 1 1
IL17A FGF6 0 0 57 237 1 1
IL17A LAMP3 0 0 252 252 1 1
IL17A SHH 0 0 154 153 1 2
IL17A KRT1 0 0 181 181 1 1
IL17A COMP 0 0 210 210 1 1
IL17A CD69 0 0 718 729 1 1
IL17A LTA 0 0 681 810 1 1
IL17A SOD1 0 0 208 208 1 2
IL17A IL7R 0 0 702 702 1 1
IL17A ARNT 0 0 203 203 1 2
IL17A P2RY12 0 0 150 169 1 1
IL17A IL36RN 0 0 509 538 1 1
IL17A CCR5 0 0 652 661 1 1
IL17A IL37 0 0 530 558 1 1
IL17A CALR 0 0 260 260 1 1
IL17A CD8A 0 0 871 874 1 1
IL17A UCHL1 0 0 339 339 1 2
IL17A BMP6 0 0 166 165 1 1
IL17A LTC4S 0 0 138 155 1 1
IL17A HAVCR2 0 0 558 558 1 1
IL17A EIF2AK2 0 0 113 150 1 2
IL17A DLL1 0 0 288 288 1 1
IL17A OSCAR 0 0 202 202 1 1
IL17A PSMB8 0 0 218 218 1 1
IL17A IGFBP3 0 0 167 167 1 2
IL17A P2RY1 0 0 89 183 1 1
IL17A LRRC32 0 0 325 325 1 1
IL17A TREM2 0 0 255 254 1 1
IL17A SLAMF1 0 0 347 399 1 1
IL17A TNFRSF13C 0 0 404 417 1 1
IL17A MMP2 0 900 460 943 1 2
IL17A RUNX3 0 0 424 424 1 1
IL17A SOX13 0 0 369 369 1 1
IL17A RIPK2 0 0 278 278 1 2
IL17A TCF7 0 0 280 292 1 1
IL17A IL22RA2 0 0 392 392 1 1
IL17A TNFRSF8 0 0 301 301 1 1
IL17A TNFSF4 0 0 556 556 1 1
IL17A COL3A1 0 0 193 193 1 1
IL17A ANGPT2 0 0 261 274 1 1
IL17A MAGEA3 0 0 160 159 1 2
IL17A ARG1 0 0 602 602 1 2
IL17A MAPK8 0 0 326 325 1 2
IL17A CPA3 0 0 143 161 1 1
IL17A KLRD1 0 0 415 414 1 1
IL17A ADIPOQ 0 0 460 459 1 2
IL17A IGHV4-38-2 0 0 244 243 1 1
IL17A SLC26A3 0 0 108 261 1 1
IL17A C5AR2 0 0 271 271 1 1
IL17A LILRB2 0 0 193 193 1 1
IL17A CALCA 0 0 292 292 1 1
IL17A HLX 0 0 231 230 1 1
IL17A HLA-DQA1 0 0 293 293 1 1
IL17A BRAF 0 0 63 192 1 2
IL17A HIST2H3PS2 0 0 323 339 1 1
IL17A HBZ 0 0 82 179 1 1
IL17A IFIH1 0 0 391 390 1 1
IL17A MMP16 0 0 54 260 1 1
IL17A STIM2 0 0 163 177 1 1
IL17A IL1F10 0 0 423 457 1 1
IL17A CEACAM8 0 0 325 325 1 1
IL17A CLDN3 0 0 212 212 1 1
IL17A VR1 0 0 292 298 1 1
IL17A BATF3 0 0 334 365 1 1
IL17A TFF1 0 0 149 172 1 1
IL17A CCR1 0 0 459 521 1 1
IL17A NR3C1 0 0 359 359 1 1
IL17A PRF1 0 0 682 686 1 1
IL17A IL2RG 0 0 394 427 1 1
IL17A MX2 0 0 164 163 1 1
IL17A PTGER4 0 0 404 404 1 1
IL17A PDGFA 0 0 155 154 1 1
IL17A CD244 0 0 308 307 1 1
IL17A CISH 0 0 459 459 1 1
IL17A FLG 0 0 508 508 1 1
IL17A P2RX7 0 0 373 390 1 2
IL17A CTGF 0 0 391 390 1 1
IL17A PLAUR 0 0 180 179 1 1
IL17A PROCR 0 0 181 181 1 1
IL17A IL12RB2 0 0 507 507 1 1
IL17A TYR 0 0 202 202 1 2
IL17A CRHR1 0 0 107 171 1 1
IL17A CX3CR1 0 0 530 531 1 1
IL17A DICER1 0 0 246 245 1 1
IL17A CFD 0 0 144 163 1 1
IL17A CYP1B1 0 0 207 207 1 1
IL17A XCR1 0 0 265 265 1 1
IL17A LIF 0 900 451 942 1 2
IL17A LTF 0 0 258 258 1 1
IL17A MUC16 0 0 153 152 1 1
IL17A HSPA4 0 0 334 334 1 1
IL17A PMEL 0 0 298 298 1 1
IL17A IL12B 0 0 171 487 1 1
IL17A IER3 0 0 161 161 1 1
IL17A CXCL9 0 0 740 752 1 1
IL17A ACHE 0 0 183 183 1 2
IL17A TEK 0 0 289 288 1 1
IL17A LPL 0 0 161 161 1 1
IL17A PPARA 0 0 336 336 1 2
IL17A DEFB103B 0 0 507 507 1 1
IL17A CCR2 0 0 633 643 1 2
IL17A ISG20 0 0 122 256 1 1
IL17A PDE6B 0 0 242 241 1 1
IL17A HSPB3 0 0 241 240 1 1
IL17A RPTOR 0 0 195 195 1 2
IL17A NES 0 0 170 169 1 2
IL17A HSP90B1 0 0 190 190 1 1
IL17A CEBPD 0 0 324 323 1 1
IL17A ITGA1 0 0 310 309 1 1
IL17A TLR7 0 0 653 655 1 2
IL17A CXCL11 0 0 609 609 1 1
IL17A IL13RA2 0 0 212 266 1 1
IL17A MAPK9 0 0 174 173 1 2
IL17A NRP1 0 0 391 390 1 1
IL17A CYCS 0 0 268 284 1 2
IL17A DUSP12 0 0 170 169 1 1
IL17A TRAF6 270 0 735 798 1 2
IL17A POMC 0 900 283 925 1 1
IL17A NANOG 0 0 155 154 1 2
IL17A HK1 0 0 81 187 1 1
IL17A IL18BP 0 0 390 390 1 1
IL17A CASP9 0 0 261 261 1 2
IL17A FASN 0 0 127 326 1 2
IL17A ETS1 0 0 325 325 1 1
IL17A FCGRT 0 0 284 284 1 1
IL17A BDKRB1 0 0 128 182 1 1
IL17A RLTPR 0 0 66 165 1 1
IL17A INSM2 0 0 206 206 1 1
IL17A CD59 0 0 181 181 1 1
IL17A BMP2 0 0 347 347 1 1
IL17A CYP27A1 0 0 211 211 1 1
IL17A RGMA 0 0 243 242 1 1
IL17A PRTN3 0 0 504 504 1 1
IL17A EGF 0 0 566 566 1 2
IL17A TMEM176B 0 0 95 207 1 1
IL17A FAM110B 0 0 0 250 1 1
IL17A PLAU 0 0 157 156 1 1
IL17A NOTCH3 0 0 167 167 1 1
IL17A IL27 0 0 519 522 1 1
IL17A IL4 0 0 914 914 1 1
IL17A IL9 0 0 857 872 1 1
IL17A RGS13 0 0 204 221 1 1
IL17A LEF1 0 0 231 230 1 1
IL17A IL17REL 0 0 219 219 1 1
IL17A PDGFRB 0 0 180 179 1 2
IL17A EP300 0 0 294 538 1 2
IL17A SIRPA 0 0 340 340 1 1
IL17A TROVE2 0 0 211 216 1 1
IL17A ADIPOR1 0 0 194 194 1 1
IL17A CNTF 0 0 294 294 1 1
IL17A SERPINB1 0 0 134 443 1 1
IL17A MYLK 0 0 194 194 1 1
IL17A MLLT4 0 0 370 394 1 1
IL17A TNFRSF10A 0 0 391 390 1 1
IL17A ROCK1 0 0 150 152 1 2
IL17A IFI44L 0 0 155 154 1 1
IL17A AMBP 0 0 286 286 1 1
IL17A DPH2 336 0 0 336 1 1
IL17A SMAD3 0 0 468 468 1 2
IL17A SPARC 0 0 150 206 1 2
IL17A IL17F 800 800 976 972 1 1
IL17A FAM213A 0 0 181 181 1 1
IL17A PDLIM4 0 0 112 161 1 1
IL17A ANXA8 0 0 260 260 1 1
IL17A BIRC3 0 0 164 176 1 1
IL17A KNG1 0 0 263 263 1 1
IL17A CCL2 0 0 843 856 1 2
IL17A RC3H1 0 0 337 337 1 1
IL17A ALB 0 0 653 689 1 2
IL17A CD68 0 0 602 609 1 2
IL17A CASP8 0 0 346 350 1 2
IL17A IDO1 0 0 564 564 1 1
IL17A LEPR 0 0 233 232 1 1
IL17A IL16 0 0 669 669 1 1
IL17A IFNE 0 0 142 183 1 1
IL17A CD276 0 0 634 640 1 1
IL17A MME 0 0 220 220 1 1
IL17A IL17RE 0 0 747 823 1 1
IL17A ELAVL1 0 0 254 254 1 2
IL17A PDC 0 0 164 163 1 1
IL17A THBS4 0 0 57 154 1 1
IL17A TYROBP 0 0 270 270 1 1
IL17A ITLN1 0 0 234 234 1 1
IL17A ITGB1 0 0 321 321 1 1
IL17A TNFAIP8L2 0 0 158 157 1 1
IL17A KAT2A 0 0 71 153 1 1
IL17A PDE4A 0 0 423 422 1 1
IL17A MAF 0 0 519 592 1 1
IL17A NFIL3 0 0 395 394 1 1
IL17A HHLA2 0 0 134 172 1 1
IL17A GATA1 0 0 181 181 1 1
IL17A DPP4 0 0 370 370 1 1
IL17A NR3C2 0 0 145 164 1 1
IL17A BSG 0 0 203 203 1 1
IL17A EREG 0 0 172 171 1 1
IL17A ALK 0 0 181 181 1 2
IL17A ABCA1 0 0 251 250 1 2
IL17A GABRB1 0 0 0 155 1 1
IL17A ROCK2 0 0 224 240 1 1
IL17A TRADD 0 0 211 211 1 1
IL17A CCL4 0 0 806 827 1 1
IL17A GBP1 0 0 142 150 1 1
IL17A IL1A 0 0 807 807 1 1
IL17A CEACAM1 0 0 233 238 1 1
IL17A MAVS 0 0 244 243 1 2
IL17A CRYGC 0 0 466 465 1 1
IL17A AIM2 0 0 391 390 1 2
IL17A DDX58 0 0 459 459 1 1
IL17A HDAC8 0 0 74 170 1 1
IL17A C4B 0 0 246 245 1 1
IL17A AGER 0 0 391 390 1 2
IL17A CCR10 0 0 497 497 1 1
IL17A HIST1H4E 0 0 155 202 1 1
IL17A PLA2G10 0 0 194 211 1 1
IL17A DUT 0 0 57 159 1 1
IL17A NCF4 0 0 190 190 1 1
IL17A DEFB4B 0 0 528 537 1 1
IL17A FGF17 0 0 52 200 1 1
IL17A CDH1 0 0 451 451 1 2
IL17A IL17RD 0 0 736 744 1 1
IL17A PDPN 0 0 310 309 1 1
IL17A TMEM201 0 0 294 294 1 1
IL17A MFGE8 0 0 181 181 1 1
IL17A MB21D1 0 0 234 234 1 1
IL17A BMP7 0 0 171 171 1 1
IL17A CD33 0 0 370 382 1 1
IL17A PADI3 0 0 152 151 1 1
IL17A PLG 0 0 328 336 1 1
IL17A TRIM21 0 0 335 335 1 1
IL17A AMICA1 0 0 193 193 1 1
IL17A ALCAM 0 0 218 218 1 1
IL17A AQP3 0 0 216 216 1 1
IL17A TIMD4 0 0 240 239 1 1
IL17A CCND1 0 0 282 282 1 2
IL17A CD274 0 0 664 671 1 2
IL17A CSF2RB 0 0 166 168 1 1
IL17A HLA-E 0 0 325 325 1 1
IL17A HDAC7 0 0 233 232 1 1
IL17A ACTA2 0 0 74 216 1 1
IL17A PDCL 0 0 229 228 1 1
IL17A FLT3LG 0 0 464 463 1 1
IL17A NOS3 0 0 325 330 1 2
IL17A SEMA3A 0 0 203 203 1 1
IL17A FIBCD1 0 0 123 157 1 1
IL17A PTAFR 0 0 161 161 1 1
IL17A ANXA2 0 0 142 181 1 1
IL17A DEFA1B 0 0 139 158 1 1
IL17A IRAK2 0 0 203 203 1 1
IL17A NCF1 0 0 321 321 1 1
IL17A CD19 0 0 711 726 1 1
IL17A ICAM2 0 0 211 211 1 1
IL17A STIM1 0 0 181 181 1 2
IL17A GPR17 0 0 219 219 1 1
IL17A SIGLEC10 0 0 67 169 1 1
IL17A IFIT2 0 0 181 181 1 1
IL17A LCE3D 0 0 172 171 1 1
IL17A CD207 0 0 468 474 1 1
IL17A PROK2 0 0 283 282 1 1
IL17A KLRG1 0 0 519 525 1 1
IL17A HMSD 0 0 0 248 1 1
IL17A HMGCR 0 0 180 179 1 1
IL17A NTRK1 0 0 194 194 1 1
IL17A CYP24A1 0 0 240 239 1 1
IL17A DEF6 0 0 306 306 1 1
IL17A SAG 0 0 218 239 1 1
IL17A CBL 0 0 154 153 1 1
IL17A SGK1 0 0 369 369 1 2
IL17A IRS1 0 0 200 200 1 2
IL17A LOX 0 0 306 306 1 2
IL17A GNLY 0 0 421 420 1 1
IL17A EGR2 0 0 330 341 1 1
IL17A RPS6KB1 0 0 270 270 1 2
IL17A ADRB2 0 0 260 260 1 1
IL17A OLIG2 0 0 137 156 1 1
IL17A HBD 0 0 194 195 1 1
IL17A AGTR1 0 0 262 262 1 1
IL17A FCGR1A 0 0 464 471 1 1
IL17A KAT2B 0 0 107 186 1 1
IL17A REM1 0 0 0 173 1 1
IL17A MUC1 0 0 325 325 1 1
IL17A HIST1H4B 0 0 155 202 1 1
IL17A NLRP2 0 0 117 172 1 1
IL17A AHR 0 0 666 672 1 2
IL17A SERPINE1 0 0 393 392 1 1
IL17A LECT2 0 0 95 151 1 1
IL17A HIST2H2BE 0 0 401 404 1 1
IL17A SLPI 0 0 284 284 1 1
IL17A WNT10B 0 0 161 161 1 1
IL17A HPGD 0 0 161 161 1 1
IL17A PECAM1 0 0 469 478 1 1
IL17A CAT 0 0 408 408 1 2
IL17A GFI1 0 0 341 351 1 1
IL17A KIR3DL1 0 0 234 234 1 1
IL17A CCL1 0 0 504 504 1 1
IL17A DEFA1 0 0 163 182 1 1
IL17A ADAMTS3 0 0 241 241 1 1
IL17A ACAT1 0 0 260 260 1 1
IL17A TXN 0 0 216 216 1 1
IL17A CANX 0 0 123 158 1 2
IL17A LCP1 0 0 81 219 1 1
IL17A ENSG00000264813 0 0 325 325 1 1
IL17A SFTPD 0 0 280 280 1 1
IL17A HGF 0 900 465 944 1 2
IL17A TRAF3IP2 270 0 637 724 1 1
IL17A RETNLB 0 0 450 450 1 1
IL17A FSTL1 0 0 413 413 1 1
IL17A POU5F1 0 0 151 150 1 2
IL17A IFI44 0 0 153 152 1 1
IL17A CD46 0 0 304 304 1 2
IL17A HPRT1 0 0 517 534 1 1
IL17A FCAR 0 0 162 161 1 1
IL17A FGF16 0 0 0 204 1 1
IL17A MLANA 0 0 171 171 1 1
IL17A PTPN2 0 0 218 218 1 2
IL17A MYB 0 0 134 173 1 1
IL17A HIST2H4B 0 0 155 202 1 1
IL17A AGBL2 0 0 134 157 1 1
IL17A SMAD6 0 0 151 150 1 1
IL17A CD38 0 0 556 556 1 2
IL17A NR1D1 0 0 181 181 1 2
IL17A SCX 0 0 0 190 1 1
IL17A CHIT1 0 0 249 263 1 1
IL17A LDLR 0 0 246 245 1 2
IL17A CCL19 0 0 558 569 1 1
IL17A CTLA4 0 0 856 861 1 2
IL17A CD97 0 0 76 232 1 1
IL17A MUC13 0 0 165 165 1 1
IL17A S100A7A 0 0 256 256 1 1
IL17A C8orf4 0 0 0 248 1 1
IL17A IL23R 0 0 806 817 1 1
IL17A IKZF4 0 0 262 274 1 1
IL17A RBFOX3 0 0 253 252 1 1
IL17A NFAT5 0 0 273 377 1 1
IL17A RPLP0 0 0 185 185 1 1
IL17A MMP7 0 0 377 432 1 1
IL17A PLA2G4D 0 0 267 283 1 1
IL17A CLEC10A 0 0 180 179 1 1
IL17A ALDH7A1 0 0 161 161 1 1
IL17A CD209 0 0 470 470 1 1
IL17A IL7 0 0 805 835 1 1
IL17A TJP2 0 0 156 155 1 1
IL17A ITK 0 0 391 390 1 1
IL17A KRT14 0 0 242 241 1 1
IL17A NT5E 0 0 518 521 1 1
IL17A SERPINB13 0 0 86 187 1 1
IL17A ADAMTS4 0 0 270 270 1 1
IL17A SLC1A5 0 0 134 188 1 1
IL17A MMP25 0 0 137 324 1 1
IL17A CD44 0 0 688 719 1 2
IL17A BDNF 0 0 423 422 1 2
IL17A NR4A2 0 0 151 157 1 1
IL17A HDC 0 0 161 161 1 1
IL17A VDR 0 0 465 465 1 2
IL17A CHIA 0 0 234 253 1 1
IL17A IL1RN 0 0 561 587 1 1
IL17A TSHR 0 0 184 183 1 1
IL17A MMP3 0 900 565 955 1 1
IL17A TNF 0 0 982 989 1 2
IL17A PLA2G2A 0 0 243 260 1 1
IL17A ADAMTSL5 0 0 350 350 1 1
IL17A IFITM1 0 0 158 157 1 1
IL17A SEMA4D 0 0 168 167 1 1
IL17A TIRAP 0 0 323 323 1 1
IL17A KYNU 0 0 167 167 1 1
IL17A MAPK1 0 0 243 242 1 2
IL17A IRF7 0 0 406 406 1 1
IL17A ITIH4 0 0 323 323 1 1
IL17A IGF1 0 0 457 457 1 2
IL17A DEFB4A 0 0 629 637 1 1
IL17A CSF1R 0 0 457 457 1 1
IL17A APOB 0 0 229 228 1 2
IL17A DDX53 0 0 286 286 1 1
IL17A SOCS4 0 0 263 263 1 1
IL17A MMP27 0 0 0 302 1 1
IL17A MERTK 0 0 240 239 1 1
IL17A ARNTL 0 0 162 161 1 1
IL17A SOCS1 0 0 519 519 1 1
IL17A BTK 0 0 310 309 1 1
IL17A RTN4IP1 0 0 227 226 1 1
IL17A FFAR3 0 0 322 321 1 1
IL17A IFNL1 0 0 402 403 1 1
IL17A CNR1 0 0 243 242 1 1
IL17A CD6 0 0 269 285 1 1
IL17A RETN 0 0 466 465 1 1
IL17A CDH5 0 0 166 165 1 1
IL17A ATF3 0 0 245 281 1 2
IL17A FGF2 0 900 646 963 1 2
IL17A IL31RA 0 0 193 193 1 1
IL17A CD9 0 0 207 207 1 1
IL17A TIGIT 0 0 413 412 1 1
IL17A CXCL3 0 0 470 616 1 1
IL17A S100A9 0 0 297 298 1 1
IL17A RELB 0 0 452 452 1 2
IL17A IFI16 0 0 145 174 1 1
IL17A BCL2A1 0 0 210 210 1 1
IL17A MMP8 0 0 422 445 1 1
IL17A IFNL2 0 0 406 407 1 1
IL17A TNFSF14 0 0 310 309 1 1
IL17A CD63 0 0 219 219 1 2
IL17A VWF 0 0 306 306 1 1
IL17A IL5 0 0 878 885 1 1
IL17A IL1R2 0 0 407 407 1 1
IL17A CD70 0 0 450 450 1 1
IL17A AGT 0 0 97 331 1 1
IL17A TFRC 0 0 350 349 1 1
IL17A ENSG00000272980 0 0 827 862 1 1
IL17A IFNAR1 0 0 459 459 1 1
IL17A HIST1H4H 0 0 155 202 1 1
IL17A TNFAIP6 0 0 306 306 1 1
IL17A NFKB2 0 0 322 334 1 1
IL17A IL34 0 0 391 390 1 1
IL17A ERAP2 0 0 171 171 1 1
IL17A SPN 0 0 325 325 1 1
IL17A ATP12A 0 0 260 260 1 1
IL17A TNFAIP3 0 0 456 456 1 2
IL17A GCG 0 0 261 261 1 1
IL17A CMKLR1 0 0 254 254 1 1
IL17A CD34 0 0 469 469 1 2
IL17A NGF 0 0 464 463 1 2
IL17A ARG2 0 0 467 467 1 1
IL17A DHODH 0 0 270 270 1 1
IL17A ERBB2 0 0 325 325 1 2
IL17A CR2 0 0 417 434 1 1
IL17A KLK1 0 0 141 160 1 1
IL17A IRF3 0 0 457 457 1 2
IL17A NLRP7 0 0 130 184 1 1
IL17A DSG3 0 0 188 188 1 1
IL17A KLK4 0 0 213 213 1 1
IL17A TH 0 0 180 180 1 2
IL17A CCL3L3 0 0 155 302 1 1
IL17A VEGFB 0 0 158 157 1 1
IL17A NR1I2 0 0 207 207 1 1
IL17A CTCFL 0 0 60 169 1 1
IL17A TNFSF8 0 0 325 339 1 1
IL17A LTB4R 0 0 324 323 1 1
IL17A CD1D 0 0 715 729 1 1
IL17A CLCA1 0 0 395 400 1 1
IL17A PDE4B 0 0 95 179 1 1
IL17A CFP 0 0 183 183 1 1
IL17A KIR2DL4 0 0 181 181 1 1
IL17A PYCARD 0 0 260 260 1 2
IL17A IL6ST 0 0 369 369 1 1
IL17A TLR9 0 0 681 700 1 2
IL17A GZMK 0 0 250 250 1 1
IL17A CREM 270 0 241 422 1 1
IL17A HIST1H2BN 0 0 144 235 1 1
IL17A GPR183 0 0 230 229 1 1
IL17A FGF3 0 0 0 205 1 1
IL17A AXL 0 0 181 181 1 2
IL17A HRH2 0 0 261 261 1 1
IL17A HSP90AB1 0 0 103 178 1 2
IL17A CYLD 0 0 184 183 1 1
IL17A EIF4EBP1 0 0 181 181 1 2
IL17A MALT1 0 0 473 473 1 1
IL17A CXCL10 0 0 806 825 1 2
IL17A USP25 0 0 233 232 1 1
IL17A ZBTB46 0 0 193 206 1 1
IL17A ID2 0 0 450 450 1 1
IL17A GPT 0 0 466 465 1 1
IL17A IL11 0 0 610 610 1 1
IL17A IFNGR2 0 0 289 288 1 1
IL17A BCL6 0 0 595 606 1 1
IL17A IL24 0 0 469 482 1 2
IL17A CD58 0 0 310 319 1 1
IL17A GJA1 0 0 183 183 1 1
IL17A BIRC5 0 0 90 152 1 2
IL17A CFH 0 0 240 239 1 1
IL17A CLEC4C 0 0 358 358 1 1
IL17A IFNLR1 0 0 225 224 1 1
IL17A FABP2 0 0 234 250 1 1
IL17A NOX4 0 0 224 224 1 2
IL17A DROSHA 0 0 174 173 1 1
IL17A KIR2DL3 0 0 242 241 1 1
IL17A XIAP 0 0 234 234 1 2
IL17A SERPINB6 0 0 57 314 1 1
IL17A PPP2R4 0 0 171 171 1 1
IL17A RUNX2 0 0 320 319 1 2
IL17A PSMD5 0 0 166 165 1 1
IL17A VIP 0 0 336 336 1 1
IL17A CD247 0 0 393 392 1 1
IL17A BRDT 0 0 95 175 1 1
IL17A ATP7A 0 0 184 183 1 1
IL17A DEFB104B 0 0 241 240 1 1
IL17A COL1A2 0 0 203 203 1 1
IL17A CLDN1 0 0 148 201 1 1
IL17A SECISBP2L 0 0 183 183 1 1
IL17A NLRC4 0 0 450 450 1 2
IL17A IKBKB 0 0 457 457 1 2
IL17A KLF4 0 0 232 244 1 2
IL17A SATB1 0 0 203 203 1 1
IL17A DUOX1 0 0 241 240 1 1
IL17A TXNDC15 273 0 0 273 1 1
IL17A PANX1 0 0 161 161 1 1
IL17A CARD14 0 0 403 403 1 1
IL17A PTHLH 0 0 164 163 1 1
IL17A FAS 0 0 469 550 1 2
IL17A CD4 0 0 915 946 1 2
IL17A INPP5D 0 0 183 183 1 1
IL17A CCL14 0 0 286 318 1 1
IL17A SEMA7A 0 0 180 179 1 1
IL17A IFIT3 0 0 243 242 1 1
IL17A VCAM1 0 0 603 603 1 1
IL17A SPIB 0 0 166 165 1 1
IL17A AKT1 0 0 601 601 1 2
IL17A TGFB2 0 0 455 455 1 1
IL17A IL17RB 0 0 877 881 1 1
IL17A HIST1H4C 0 0 155 202 1 1
IL17A PPARG 0 0 505 505 1 2
IL17A CSF2 0 0 870 878 1 1
IL17A IL12RB1 0 0 666 666 1 1
IL17A LY96 0 0 390 390 1 1
IL17A IL17C 0 0 710 264 1 1
IL17A ACKR1 0 0 244 243 1 1
IL17A MKI67 0 0 103 453 1 2
IL17A CD48 0 0 152 289 1 1
IL17A IFIT1 0 0 245 244 1 1
IL17A MMP10 0 0 218 341 1 1
IL17A CCR4 0 0 282 287 1 1
IL17A RIPK3 0 0 170 169 1 2
IL17A REG3A 0 0 413 429 1 1
IL17A TXLNA 0 0 341 341 1 1
IL17A CTCF 0 0 108 245 1 1
IL17A TRPV4 0 0 582 582 1 1
IL17A PRKCD 0 0 206 220 1 2
IL17A CD2 0 0 427 426 1 1
IL17A CDKN1B 0 0 150 173 1 2
IL17A IKZF2 0 0 296 307 1 1
IL17A DPP8 313 0 49 318 1 1
IL17A ADORA2B 0 0 269 269 1 1
IL17A SCGB1A1 0 0 247 246 1 1
IL17A GHITM 0 0 232 231 1 1
IL17A PF4 0 0 325 336 1 1
IL17A STAT5B 0 0 653 708 1 1
IL17A HRH4 0 0 325 325 1 1
IL17A KRT19 0 0 142 165 1 1
IL17A TGFB1 0 900 518 960 1 2
IL17A NFATC2 0 0 400 400 1 1
IL17A P2RX1 0 0 155 174 1 1
IL17A RAC2 0 0 181 181 1 1
IL17A KLRB1 0 0 702 702 1 1
IL17A CLDN4 0 0 230 229 1 1
IL17A ICOS 0 0 505 535 1 1
IL17A MMP12 0 0 409 425 1 1
IL17A ANPEP 0 0 211 211 1 1
IL17A IL4I1 0 0 166 188 1 1
IL17A KDR 0 0 294 294 1 2
IL17A RARRES2 0 0 293 293 1 1
IL17A JAK1 0 0 557 557 1 2
IL17A AP1S3 0 0 126 157 1 1
IL17A HIST1H4D 0 0 155 202 1 1
IL17A HMOX1 0 0 451 451 1 2
IL17A FOXP3 0 0 904 905 1 2
IL17A IL32 0 0 518 518 1 1
IL17A NCR2 0 0 518 518 1 1
IL17A TBK1 0 0 294 294 1 2
IL17A PPBP 0 0 465 501 1 1
IL17A ADIPOR2 0 0 165 176 1 1
IL17A NDFIP1 0 0 150 234 1 1
IL17A EIF2AK3 0 0 263 263 1 2
IL17A CCR8 0 0 415 440 1 1
IL17A HNF4A 0 0 181 181 1 1
IL17A SERPINB7 0 0 52 558 1 1
IL17A FAM110A 0 0 0 544 1 1
IL17A A2M 0 0 194 194 1 1
IL17A SLC6A20 0 0 180 180 1 1
IL17A STAT6 0 0 667 726 1 1
IL17A RNASE7 0 0 269 269 1 1
IL17A SERPINB3 0 0 143 670 1 1
IL17A TNFSF12 0 0 288 288 1 1
IL17A TLR3 0 0 776 777 1 2
IL17A RSAD2 0 0 181 181 1 1
IL17A IL19 0 0 602 611 1 1
IL17A HRH1 0 0 295 295 1 1
IL17A MIF 0 0 502 512 1 2
IL17A LGALS3 0 0 400 437 1 2
IL17A RGS18 0 0 164 163 1 1
IL17A CADM1 0 0 241 240 1 1
IL17A CD52 0 0 322 321 1 1
IL17A TNFRSF18 0 0 610 613 1 1
IL17A FLT1 0 0 299 299 1 1
IL17A CD93 0 0 142 174 1 1
IL17A DKK1 0 0 283 282 1 1
IL17A SRC 0 0 419 418 1 2
IL17A ADA 0 0 267 267 1 1
IL17A IRF8 0 0 421 420 1 1
IL17A CD3G 0 0 230 229 1 1
IL17A HP 0 0 390 390 1 1
IL17A CDC42 0 0 216 216 1 2
IL17A RAG1 0 0 594 594 1 1
IL17A MCM3 0 0 67 155 1 1
IL17A F2 0 0 240 268 1 1
IL17A SLK 0 0 217 217 1 1
IL17A BPI 0 0 193 193 1 1
IL17A MB 0 0 142 160 1 2
IL17A IL25 0 0 758 758 1 1
IL17A CD47 0 0 310 309 1 2
IL17A BGLAP 0 0 322 321 1 1
IL17A TNFSF11 0 0 710 716 1 2
IL17A DHFRL1 0 0 0 206 1 1
IL17A APOE 0 0 424 424 1 2
IL17A PCSK9 0 0 120 183 1 1
IL17A IL26 0 0 682 719 1 1
IL17A SLC2A4 0 0 157 156 1 1
IL17A IL36B 0 0 370 414 1 1
IL17A FOXO3 0 0 285 284 1 2
IL17A GSK3B 0 0 157 209 1 2
IL17A MRC1 0 0 556 556 1 1
IL17A TTR 0 0 156 155 1 1
IL17A BLK 0 0 162 161 1 1
IL17A S100B 0 0 266 266 1 1
IL17A SLC11A1 0 0 230 229 1 1
IL17A ITGAX 0 0 769 817 1 1
IL17A FGF8 0 0 0 189 1 1
IL17A GUSB 0 0 244 243 1 1
IL17A FABP4 0 0 173 173 1 1
IL17A SOCS2 0 0 320 319 1 1
IL17A ALX3 0 0 0 209 1 1
IL17A CXCL16 0 0 370 370 1 1
IL17A CDKN2A 0 0 261 261 1 2
IL17A CASP4 0 0 163 183 1 2
IL17A S100A12 0 0 390 391 1 1
IL17A SH2D1A 0 0 218 253 1 1
IL17A CD5L 0 0 219 219 1 1
IL17A PIGR 0 0 455 455 1 1
IL17A KLF2 0 0 272 284 1 1
IL17A CHUK 0 0 418 418 1 1
IL17A HIST2H4A 0 0 155 202 1 1
IL17A IL1RAP 0 0 391 390 1 1
IL17A KLK11 0 0 202 202 1 1
IL17A DLAT 0 0 161 161 1 1
IL17A WNT2 0 0 95 242 1 1
IL17A GPR126 0 0 252 252 1 1
IL17A PIK3CD 0 0 241 240 1 1
IL17A IL13RA1 0 0 242 289 1 1
IL17A FGF9 0 0 119 273 1 1
IL17A CEBPB 0 0 451 451 1 2
IL17A ATG16L1 0 0 391 390 1 2
IL17A DHFR 0 0 127 277 1 1
IL17A CIITA 0 0 285 284 1 1
IL17A TSPO 0 0 153 152 1 1
IL17A NOD2 0 0 615 615 1 2
IL17A TG 0 0 277 277 1 1
IL17A RIPK1 0 0 242 241 1 2
IL17A CSF1 0 0 632 640 1 1
IL17A HDAC1 270 0 226 426 1 2
IL17A PRDM1 0 0 468 479 1 1
IL17A C2CD4D 0 0 0 181 1 1
IL17A LTBR 0 0 418 425 1 1
IL17A FGF11 0 0 0 203 1 1
IL17A GPI 0 0 220 220 1 2
IL17A ELF3 0 0 134 188 1 1
IL17A MMP14 0 0 183 213 1 1
IL17A KIR2DL1 0 0 202 202 1 1
IL17A HDAC9 0 0 163 163 1 1
IL17A REL 0 0 470 470 1 2
IL17A NLRP3 0 0 705 705 1 2
IL17A GFPT1 0 0 235 235 1 1
IL17A CXCL1 0 0 802 856 1 2
IL17A APCS 0 0 212 212 1 1
IL17A IL33 0 0 759 759 1 2
IL17A CASP3 0 0 504 504 1 2
IL17A NQO1 0 0 154 153 1 2
IL17A F3 0 0 342 342 1 1
IL17A PSMB9 0 0 202 202 1 1
IL17A FGF19 0 0 74 240 1 1
IL17A CCL11 0 0 804 842 1 1
IL17A PTGS2 0 0 595 597 1 2
IL17A NKG7 0 0 167 167 1 1
IL17A AICDA 0 0 390 403 1 1
IL17A MSR1 0 0 246 245 1 1
IL17A FIGF 0 0 325 325 1 1
IL17A IL1RL1 0 0 509 516 1 1
IL17A PGLYRP1 0 0 184 183 1 1
IL17A FCN2 0 0 151 150 1 1
IL17A AFP 0 0 203 241 1 2
IL17A TNFRSF10B 0 0 234 234 1 2
IL17A IL13 0 0 901 904 1 2
IL17A CD1B 0 0 501 523 1 1
IL17A RNASE2 0 0 261 261 1 1
IL17A PRKCQ 0 0 212 261 1 2
IL17A REN 0 0 325 336 1 1
IL17A ALOX5 0 0 325 325 1 1
IL17A TNFSF13B 0 0 987 987 1 1
IL17A VIL1 0 0 181 181 1 1
IL17A FGF22 0 0 0 205 1 1
IL17A ANG 0 0 204 204 1 2
IL17A KLK5 0 0 155 154 1 1
IL17A NOTCH2 0 0 253 252 1 1
IL17A ACE 0 0 336 336 1 1
IL17A PPIA 0 0 225 224 1 1
IL17A CXCL5 0 0 666 740 1 1
IL17A BTN1A1 0 0 125 155 1 1
IL17A CYBB 0 0 424 424 1 2
IL17A CD28 0 0 821 847 1 1
IL17A CD5 0 0 517 540 1 1
IL17A VEGFC 0 0 336 336 1 1
IL17A GPR65 0 0 156 155 1 1
IL17A IL2 457 0 878 936 1 1
IL17A TLR6 0 0 497 593 1 1
IL17A OLR1 0 0 225 224 1 2
IL17A ANXA1 0 0 249 248 1 1
IL17A ITGA2 0 0 403 447 1 1
IL17A ALDH1A1 0 0 170 169 1 1
IL17A LRP1 0 0 212 212 1 1
IL17A MUC4 0 0 245 244 1 1
IL17A CCL7 0 0 637 667 1 1
IL17A BECN1 0 0 254 254 1 2
IL17A ABCB1 0 0 155 162 1 2
IL17A THBS1 0 0 323 323 1 1
IL17A FBXL19 0 0 170 169 1 1
IL17A PTGES 0 0 310 309 1 1
IL17A SDC1 0 0 467 477 1 1
IL17A MFI2 0 0 0 158 1 1
IL17A PTGER3 0 0 216 216 1 1
IL17A TOLLIP 0 0 202 202 1 1
IL17A HSH2D 0 0 181 181 1 1
IL17A MET 0 0 204 204 1 2
IL17A SSB 0 0 246 245 1 1
IL17A TRAF3 0 0 406 406 1 2
IL17A DUSP1 0 0 299 299 1 1
IL17A FGF23 0 0 154 173 1 1
IL17A MAPK11 0 0 152 224 1 1
IL17A FLT4 0 0 213 213 1 1
IL17A TLR2 0 0 839 845 1 2
IL17A ENSG00000277117 0 0 556 565 1 1
IL17A BGN 0 0 170 169 1 1
IL17A TACR1 0 0 193 193 1 1
IL17A IL18R1 0 0 401 432 1 1
IL17A CD86 0 0 720 743 1 1
IL17A NOD1 0 0 504 504 1 2
IL17A IFNA17 0 0 341 341 1 1
IL17A TFG 0 0 436 436 1 1
IL17A CARD11 0 0 284 284 1 1
IL17A HLA-DRA 0 0 185 185 1 1
IL17A CFB 0 0 204 225 1 1
IL17A CD81 0 0 206 206 1 1
IL17A SERPINB4 0 0 193 228 1 1
IL17A CD72 0 0 123 178 1 1
IL17A MADCAM1 0 0 404 404 1 1
IL17A PGF 0 0 341 341 1 1
IL17A SOCS3 0 0 601 601 1 1
IL17A IL15RA 0 0 210 210 1 1
IL17A CLEC9A 0 0 260 260 1 1
IL17A IL31 0 0 651 651 1 1
IL17A FOS 0 0 427 454 1 2
IL17A KDM6B 0 0 203 203 1 1
IL17A FASLG 0 0 560 560 1 1
IL17A S100A8 0 0 372 372 1 2
IL17A CCL27 0 0 682 682 1 1
IL17A TWIST1 0 0 161 161 1 1
IL17A IFNL3 0 0 267 268 1 1
IL17A FCER1A 0 0 248 248 1 1
IL17A PTPN11 0 0 321 321 1 1
IL17A IRAK3 0 0 286 286 1 1
IL17A TNIP1 0 0 325 325 1 1
IL17A SIGIRR 0 0 366 366 1 1
IL17A AQP4 0 0 370 370 1 1
IL17A CLDN2 0 0 325 325 1 1
IL17A STAT5A 0 0 702 751 1 1
IL17A VTCN1 0 0 296 296 1 1
IL17A MMP24 0 0 115 307 1 1
IL17A G6PC2 0 0 160 159 1 1
IL17A IRG1 0 0 140 179 1 1
IL17A EMR3 0 0 0 203 1 1
IL17A CCL8 0 0 423 537 1 1
IL17A CAMK4 0 0 233 232 1 1
IL17A SERPINB12 0 0 0 189 1 1
IL17A VIPR1 0 0 181 181 1 1
IL17A CD96 0 0 146 174 1 1
IL17A FOXP2 0 0 262 262 1 1
IL17A HSPA5 0 0 203 203 1 2
IL17A SOD2 0 0 194 194 1 2
IL17A CD3E 0 0 556 611 1 1
IL17A HLA-B 0 0 270 270 1 1
IL17A CCL17 0 0 650 657 1 1
IL17A IFNGR1 0 0 456 493 1 1
IL17A PTH 0 0 482 482 1 1
IL17A GPX2 0 0 107 168 1 1
IL17A PADI2 0 0 207 207 1 1
IL17A RNASE3 0 0 400 400 1 1
IL17A RANGRF 0 0 123 212 1 1
IL17A EPAS1 0 0 73 265 1 2
IL17A LILRB4 0 0 247 246 1 1
IL17A ITGB2 0 0 344 343 1 1
IL17A KRAS 0 0 310 353 1 2
IL17A FOXO1 0 0 381 381 1 2
IL17A C3 0 0 457 457 1 2
IL17A IL5RA 0 0 260 260 1 1
IL17A MMP13 0 0 468 468 1 2
IL17A TFF2 0 0 193 193 1 1
IL17A CXCR5 0 0 681 686 1 1
IL17A RARA 0 0 143 169 1 2
IL17A RARS 0 0 155 154 1 1
IL17A CCR9 0 0 558 567 1 1
IL17A RAG2 0 0 517 517 1 1
IL17A IKBKG 0 0 404 404 1 1
IL17A CCR7 0 0 683 689 1 1
IL17A GPX1 0 0 140 179 1 1
IL17A FN1 0 0 596 596 1 2
IL17A TBP 0 0 188 188 1 1
IL17A KLRC2 0 0 241 240 1 1
IL17A VTN 0 0 173 173 1 1
IL17A NCAM1 0 0 595 595 1 1
IL17A TBX21 0 0 857 860 1 1
IL17A PRKCA 0 0 165 165 1 1
IL17A DST 0 0 161 161 1 2
IL17A THPO 0 0 276 276 1 1
IL17A ELANE 0 0 519 522 1 1
IL17A ADAM17 0 0 325 325 1 1
IL17A LOR 0 0 370 370 1 1
IL17A HAND2 0 0 0 556 1 1
IL17A SPHK1 0 0 243 242 1 2
IL17A SERPINB9 0 0 119 358 1 1
IL17A SERPINB8 0 0 0 553 1 1
IL17A NFKBIB 0 0 147 241 1 1
IL17A TIMP2 0 0 310 309 1 1
IL17A MAP1LC3B 0 0 143 160 1 2
IL17A SPHK2 0 0 181 181 1 1
IL17A TMEM79 0 0 154 153 1 1
IL17A PIAS3 0 0 207 207 1 1
IL17A SERPINB5 0 0 67 565 1 1
IL17A XCL1 0 0 391 392 1 1
IL17A MCAM 0 0 408 408 1 1
IL17A ISG15 0 0 285 284 1 2
IL17A CD1E 0 0 464 490 1 1
IL17A HSPB2 0 0 167 167 1 1
IL17A TERT 0 0 137 156 1 2
IL17A OBBP2 0 0 109 304 1 1
IL17A EPX 0 0 317 329 1 1
IL17A TET2 0 0 418 418 1 2
IL17A VAV1 0 0 278 278 1 1
IL17A ADRB1 0 0 134 152 1 1
IL17A TYRP1 0 0 171 171 1 1
IL17A CMA1 0 0 324 323 1 1
IL17A KCNN4 0 0 181 181 1 1
IL17A ENSG00000255819 0 0 561 577 1 1
IL17A NCF2 0 0 182 181 1 1
IL17A HSPB1 0 0 181 181 1 2
IL17A SOCS6 0 0 245 244 1 1
IL17A TGFBR1 0 0 266 266 1 1
IL17A DLEU7 0 0 0 155 1 1
IL17A USP18 0 0 167 240 1 1
IL17A IL22RA1 0 0 601 601 1 1
IL17A S100A4 0 0 217 250 1 1
IL17A HLA-C 0 0 323 323 1 1
IL17A ATP4A 0 0 259 258 1 1
IL17A IRF1 0 0 460 459 1 2
IL17A ELN 0 0 336 336 1 1
IL17A EBI3 0 0 260 310 1 1
IL17A XBP1 0 0 282 282 1 2
IL17A GYPA 0 0 182 181 1 1
IL17A STAT2 0 0 339 497 1 1
IL17A CXCR3 0 0 709 709 1 1
IL17A CRH 0 0 202 202 1 1
IL17A ITGB3 0 0 175 175 1 1
IL17A LGR5 0 0 242 241 1 1
IL17A TLR8 0 0 518 518 1 1
IL17A SPX 0 0 0 154 1 1
IL17A WNT3A 0 0 170 176 1 2
IL17A MT-ND1 0 0 0 248 1 1
IL17A ATG5 0 0 282 282 1 2
IL17A RNF114 0 0 183 183 1 1
IL17A ESR1 0 0 365 365 1 2
IL17A IRF5 0 0 395 394 1 1
IL17A HMGB1 0 0 560 560 1 2
IL17A DUOX2 0 0 241 240 1 1
IL17A IFNB1 0 0 681 687 1 1
IL17A LYN 0 0 234 234 1 1
IL17A CTSK 0 0 418 418 1 2
IL17A BTNL2 0 0 150 165 1 1
IL17A TUBB 0 0 156 155 1 1
IL17A SMAD7 0 0 372 372 1 1
IL17A RGS1 0 0 155 173 1 1
IL17A T 0 0 286 286 1 1
IL17A P2RY2 0 0 211 211 1 1
IL17A TRPA1 0 0 208 208 1 1
IL17A ITGAM 0 0 769 817 1 1
IL17A PDCD1 0 0 561 583 1 2
IL17A GATA2 0 0 181 198 1 1
IL17A DSG1 0 0 196 196 1 1
IL17A MAP3K5 0 0 170 169 1 1
IL17A ACKR2 0 0 612 612 1 1
IL17A EOMES 0 0 558 558 1 1
IL17A MCL1 0 0 280 280 1 2
IL17A AIRE 0 0 519 519 1 1
IL17A SIRT1 0 0 323 323 1 2
IL17A IL10RB 0 0 504 515 1 1
IL17A CR1 0 0 171 196 1 1
IL17A CTF1 0 0 182 181 1 1
IL17A NOX1 0 0 253 252 1 1
IL17A SPI1 0 0 451 451 1 1
IL17A PRL 0 0 261 276 1 1
IL17A CTSB 0 0 282 282 1 2
IL17A FCGR2A 0 0 607 620 1 1
IL17A SREBF1 0 0 203 203 1 1
IL17A HIST1H4K 0 0 155 202 1 1
IL17A CD79A 0 0 188 188 1 1
IL17A NGFR 0 0 181 181 1 1
IL17A HIST1H4A 0 0 155 202 1 1
IL17A CDX2 0 0 118 211 1 1
IL17A TIMP3 0 0 207 207 1 1
IL17A CD226 0 0 317 317 1 1
IL17A RORB 0 0 193 310 1 1
IL17A MAPK14 0 0 320 434 1 2
IL17A RORC 0 0 804 889 1 1
IL17A CSF3R 0 0 233 232 1 1
IL17A CLEC4E 0 0 466 465 1 1
IL17A MGEA5 0 0 171 171 1 1
IL17A DOCK8 0 0 325 333 1 1
IL17A TNFRSF9 0 0 469 469 1 1
IL17A IL21R 0 0 556 559 1 1
IL17A CNTN2 0 0 309 309 1 1
IL17A S1PR1 0 0 417 424 1 1
IL17A LEP 0 0 560 562 1 1
IL17A SYK 0 0 518 519 1 2
IL17A KIT 0 0 506 514 1 2
IL17A NFKBIA 0 0 560 560 1 2
IL17A LDHA 0 0 181 181 1 2
IL17A ZC3H12A 0 0 362 362 1 1
IL17A TCF4 0 0 162 161 1 1
IL17A BMP4 0 0 170 169 1 1
IL17A MMP11 0 0 123 315 1 1
IL17A PDCD1LG2 0 0 517 520 1 1
IL17A CD200 0 0 325 325 1 1
IL17A NFATC1 0 0 467 487 1 2
IL17A FFAR4 0 0 181 181 1 1
IL17A FCER1G 0 0 176 249 1 1
IL17A EDIL3 0 0 441 441 1 1
IL17A GAPDHS 0 0 0 313 1 1
IL17A CASP5 0 0 142 162 1 1
IL17A YARS 0 0 150 178 1 1
IL17A IL20 0 0 0 206 1 1
IL17A PTEN 0 0 340 340 1 2
IL17A SIGLEC8 0 0 138 155 1 1
IL17A MBP 0 0 563 574 1 2
IL17A ID3 0 0 234 234 1 1
IL17A BST2 0 0 247 246 1 1
IL17A TNFRSF11A 0 0 324 323 1 1
IL17A MAPK7 0 0 167 167 1 1
IL17A NLRP6 0 0 359 359 1 1
IL17A IFNA21 0 0 335 335 1 1
IL17A FPR1 0 0 234 234 1 1
IL17A IRF4 0 0 660 716 1 1
IL17A GC 0 0 249 248 1 1
IL17A KRT16 0 0 341 341 1 1
IL17A VEGFA 0 900 739 972 1 2
IL17A LTA4H 0 0 160 159 1 1
IL17A RBPJ 0 0 260 260 1 1
IL17A IRAK4 0 0 392 392 1 1
IL17A CXCL2 0 0 700 782 1 1
IL17A COL1A1 0 0 286 286 1 2
IL17A NAMPT 0 0 268 268 1 2
IL17A FLT3 0 0 400 400 1 2
IL17A CDR2 0 0 134 152 1 1
IL17A IL10 0 900 915 994 1 2
IL17A SNAI1 0 0 215 215 1 1
IL17A HBB 0 0 167 168 1 1
IL17A CCL20 0 0 770 776 1 1
IL17A GFAP 0 0 325 337 1 2
IL17A CXCR6 0 0 504 504 1 1
IL17A ACTG1 0 0 330 355 1 1
IL17A CCL23 0 0 295 295 1 1
IL17A NR1H4 0 0 218 218 1 1
IL17A IKZF1 0 0 324 335 1 1
IL17A GDF15 0 0 173 173 1 1
IL17A FOSL2 0 0 210 247 1 1
IL17A CDH11 0 0 158 168 1 1
IL17A ATG7 0 0 195 195 1 2
IL17A FOSB 0 0 170 209 1 1
IL17A TGFBR2 0 0 369 369 1 1
IL17A GPR15 0 0 170 206 1 1
IL17A SELE 0 0 517 517 1 1
IL17A TJP1 0 0 424 424 1 1
IL17A TAC1 0 0 341 341 1 1
IL17A BAZ2B 0 0 49 152 1 1
IL17A FGF12 0 0 0 191 1 1
IL17A GOT2 0 0 234 234 1 1
IL17A ENG 0 0 350 349 1 2
IL17A CTSG 0 0 391 390 1 1
IL17A CCL3 0 0 807 840 1 1
IL17A FCGR3B 0 0 653 653 1 1
IL17A CCL22 0 0 650 650 1 1
IL17A KLK6 0 0 151 150 1 1
IL17A ICAM3 0 0 248 248 1 1
IL17A HLA-A 0 0 309 309 1 1
IL17A COL17A1 0 0 247 246 1 1
IL17A LITAF 0 0 233 696 1 1
IL17A GAD2 0 0 292 292 1 1
IL17A ITGA2B 0 0 181 181 1 1
IL17A KCNA3 0 0 243 319 1 1
IL17A ATM 0 0 180 179 1 2
IL17A IL18RAP 0 0 304 304 1 1
IL17A THBD 0 0 334 334 1 1
IL17A IL23A 0 900 804 980 1 1
IL17A CTSD 0 0 158 157 1 2
IL17A MARCO 0 0 194 194 1 1
IL17A TYRO3 0 0 163 163 1 1
IL17A SERPINC1 0 0 155 154 1 1
IL17A S1PR5 0 0 241 240 1 1
IL17A IGF2 0 0 163 163 1 1
IL17A SULT2B1 0 0 358 358 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0005125 Molecular Function cytokine activity enables IDA
GO:0005515 Molecular Function protein binding enables IPI
GO:0046982 Molecular Function protein heterodimerization activity enables IEA
GO:0042803 Molecular Function protein homodimerization activity enables IEA
GO:0007219 Biological Process Notch signaling pathway involved_in IEA
GO:0002250 Biological Process adaptive immune response involved_in IEA
GO:0006915 Biological Process apoptotic process involved_in TAS
GO:0008219 Biological Process cell death involved_in TAS
GO:0007267 Biological Process cell-cell signaling involved_in TAS
GO:0071347 Biological Process cellular response to interleukin-1 involved_in IEA
GO:0050829 Biological Process defense response to Gram-negative bacterium involved_in IEA
GO:0050830 Biological Process defense response to Gram-positive bacterium involved_in IEA
GO:0050832 Biological Process defense response to fungus involved_in IEA
GO:0072537 Biological Process fibroblast activation involved_in IDA
GO:0010467 Biological Process gene expression involved_in IEA
GO:0097530 Biological Process granulocyte migration involved_in IEA
GO:0006955 Biological Process immune response involved_in TAS
GO:0006954 Biological Process inflammatory response involved_in IEA
GO:0045087 Biological Process innate immune response involved_in IEA
GO:0097400 Biological Process interleukin-17-mediated signaling pathway involved_in IDA
GO:0038173 Biological Process interleukin-17A-mediated signaling pathway involved_in IDA
GO:0060729 Biological Process intestinal epithelial structure maintenance involved_in IEA
GO:0030216 Biological Process keratinocyte differentiation involved_in IEA
GO:0043616 Biological Process keratinocyte proliferation involved_in IEA
GO:0106015 Biological Process negative regulation of inflammatory response to wounding involved_in IEA
GO:0002225 Biological Process positive regulation of antimicrobial peptide production involved_in IEA
GO:1903348 Biological Process positive regulation of bicellular tight junction assembly involved_in IEA
GO:2000340 Biological Process positive regulation of chemokine (C-X-C motif) ligand 1 production involved_in IDA
GO:1900017 Biological Process positive regulation of cytokine production involved in inflammatory response acts_upstream_of_or_within IDA
GO:0032731 Biological Process positive regulation of interleukin-1 beta production acts_upstream_of_or_within IDA
GO:0032735 Biological Process positive regulation of interleukin-12 production acts_upstream_of_or_within IDA
GO:0032739 Biological Process positive regulation of interleukin-16 production acts_upstream_of_or_within IDA
GO:0032747 Biological Process positive regulation of interleukin-23 production involved_in IDA
GO:0032755 Biological Process positive regulation of interleukin-6 production involved_in IDA
GO:0045672 Biological Process positive regulation of osteoclast differentiation involved_in IDA
GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II acts_upstream_of_or_within IDA
GO:0032760 Biological Process positive regulation of tumor necrosis factor production acts_upstream_of_or_within IDA
GO:0009611 Biological Process response to wounding involved_in IDA
GO:0009897 Cellular Component external side of plasma membrane located_in IEA
GO:0005576 Cellular Component extracellular region located_in TAS
GO:0005615 Cellular Component extracellular space is_active_in IDA
Pathways
Name DB ID
Cytokine Signaling in Immune system Reactome R-HSA-1280215
Disease Reactome R-HSA-1643685
Immune System Reactome R-HSA-168256
Interleukin-17 signaling Reactome R-HSA-448424
Signaling by Interleukins Reactome R-HSA-449147
Infectious disease Reactome R-HSA-5663205
Interleukin-4 and Interleukin-13 signaling Reactome R-HSA-6785807
SARS-CoV Infections Reactome R-HSA-9679506
SARS-CoV-2 Infection Reactome R-HSA-9694516
SARS-CoV-2 activates/modulates innate and adaptive immune responses Reactome R-HSA-9705671
SARS-CoV-2-host interactions Reactome R-HSA-9705683
Viral Infection Pathways Reactome R-HSA-9824446
Network map of SARS-CoV-2 signaling pathway (WP5115) WikiPathways WP5115_r124648
Development and heterogeneity of the ILC family (WP3893) WikiPathways WP3893_r118859
Overview of proinflammatory and profibrotic mediators (WP5095) WikiPathways WP5095_r120801
T-cell receptor signaling pathway (WP69) WikiPathways WP69_r120966
Prostaglandin signaling (WP5088) WikiPathways WP5088_r119639
Neurogenesis regulation in the olfactory epithelium (WP5265) WikiPathways WP5265_r123524
Immune infiltration in pancreatic cancer (WP5285) WikiPathways WP5285_r124598
Allograft rejection (WP2328) WikiPathways WP2328_r120805
Th17 cell differentiation pathway (WP5130) WikiPathways WP5130_r123523
COVID-19 and endothelial cell senescence (WP5256) WikiPathways WP5256_r124640
Oxysterols derived from cholesterol (WP4545) WikiPathways WP4545_r123863
IL-17 signaling pathway (WP2112) WikiPathways WP2112_r117960
T-cell activation SARS-CoV-2 (WP5098) WikiPathways WP5098_r119538
Transcripts
Accession Version MolecularType Name NCBI Comments
NM_002190 3 mRNA None NC_000006 Reference