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IRS1

insulin receptor substrate 1
General Information
Name insulin receptor substrate 1
Alias
  • insulin receptor substrate 1
Gene_family Pleckstrin homology domain containing
organism Homo sapiens
entrez_id 3667
location 2q36.3
transcript_count 3
exon_count 4
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. [provided by RefSeq, Nov 2009]
    Stringdb Insulin receptor substrate 1; May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity)
    nextProt May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity).
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
IRS1 BioGRID IRS2 GeneID BioGRID Co-fractionation; Negative Genetic
IRS1 BioGRID ATG16L1 GeneID BioGRID Proximity Label-MS
IRS1 BioGRID CIAO1 GeneID BioGRID Proximity Label-MS
IRS1 BioGRID TRIM72 GeneID BioGRID Affinity Capture-Western; Co-localization; PCA; Reconstituted Complex
IRS1 BioGRID TOP3B GeneID BioGRID Affinity Capture-RNA
IRS1 BioGRID YWHAQ GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
IRS1 BioGRID YWHAH GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Proximity Label-MS
IRS1 BioGRID YWHAG GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
IRS1 BioGRID PIK3CA GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
IRS1 BioGRID ZRANB1 GeneID BioGRID Affinity Capture-MS
IRS1 BioGRID GLB1 GeneID BioGRID Co-fractionation
IRS1 BioGRID GDI1 GeneID BioGRID Co-fractionation
IRS1 BioGRID DLG1 GeneID BioGRID Co-fractionation
IRS1 BioGRID UNC13D GeneID BioGRID Co-fractionation
IRS1 BioGRID NIBAN2 GeneID BioGRID Co-fractionation
IRS1 BioGRID ATPAF1 GeneID BioGRID Co-fractionation
IRS1 BioGRID RPRD1A GeneID BioGRID Co-fractionation
IRS1 BioGRID FAIM GeneID BioGRID Co-fractionation
IRS1 BioGRID TRIM29 GeneID BioGRID Co-fractionation
IRS1 BioGRID KHDRBS1 GeneID BioGRID Affinity Capture-Western; Co-fractionation; FRET
IRS1 BioGRID LAMTOR3 GeneID BioGRID Co-fractionation
IRS1 BioGRID PIK3R1 GeneID BioGRID Affinity Capture-Luminescence; Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Far Western; Protein-peptide; Reconstituted Complex; Two-hybrid
IRS1 BioGRID LRPAP1 GeneID BioGRID Co-fractionation
IRS1 BioGRID PELI2 GeneID BioGRID Affinity Capture-Western; Two-hybrid
IRS1 BioGRID IGF1R GeneID BioGRID Affinity Capture-Western; Two-hybrid
IRS1 BioGRID TRAF4 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
IRS1 BioGRID YWHAB GeneID BioGRID Affinity Capture-MS; Reconstituted Complex
IRS1 BioGRID FBXW8 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
IRS1 BioGRID KLHL13 GeneID BioGRID Affinity Capture-Western; Proximity Label-MS
IRS1 BioGRID KLHL9 GeneID BioGRID Affinity Capture-Western; Proximity Label-MS
IRS1 BioGRID CUL3 GeneID BioGRID Affinity Capture-Western
IRS1 BioGRID DYRK1A GeneID BioGRID Affinity Capture-MS
IRS1 BioGRID Trp53 GeneID BioGRID Affinity Capture-Western
IRS1 BioGRID Mdm2 GeneID BioGRID Affinity Capture-Western
IRS1 BioGRID ZDHHC23 GeneID BioGRID Affinity Capture-MS
IRS1 BioGRID ZDHHC18 GeneID BioGRID Affinity Capture-MS
IRS1 BioGRID RAD51 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
IRS1 BioGRID USP9X GeneID BioGRID Affinity Capture-Western
IRS1 BioGRID GRB2 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Protein-peptide; Reconstituted Complex
IRS1 BioGRID PTPN11 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Protein-peptide; Reconstituted Complex
IRS1 BioGRID JAK2 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
IRS1 BioGRID IRS1 GeneID BioGRID Biochemical Activity
IRS1 BioGRID INSR GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex; Two-hybrid
IRS1 BioGRID CBLB GeneID BioGRID Affinity Capture-Western
IRS1 BioGRID CBL GeneID BioGRID Affinity Capture-Western
IRS1 BioGRID SH2B1 GeneID BioGRID Affinity Capture-Western; Protein-peptide
IRS1 BioGRID VIRMA GeneID BioGRID Affinity Capture-RNA
IRS1 BioGRID CD2AP GeneID BioGRID Affinity Capture-Western
IRS1 BioGRID PTPRF GeneID BioGRID Affinity Capture-Western
IRS1 BioGRID PASK GeneID BioGRID Biochemical Activity
IRS1 BioGRID CD36 GeneID BioGRID Affinity Capture-Western
IRS1 BioGRID Syp GeneID BioGRID Affinity Capture-Western
IRS1 BioGRID Grb2 GeneID BioGRID Affinity Capture-Western
IRS1 BioGRID FYN GeneID BioGRID Affinity Capture-Western
IRS1 BioGRID CUL7 GeneID BioGRID Affinity Capture-Western
IRS1 BioGRID SOCS1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
IRS1 BioGRID GSK3B GeneID BioGRID Affinity Capture-Western
IRS1 BioGRID PIK3CB GeneID BioGRID Affinity Capture-Western
IRS1 BioGRID PIK3R2 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
IRS1 BioGRID MTOR GeneID BioGRID Affinity Capture-Western; Biochemical Activity
IRS1 BioGRID CSNK2B GeneID BioGRID Affinity Capture-MS
IRS1 BioGRID CSNK2A2 GeneID BioGRID Affinity Capture-MS
IRS1 BioGRID CSNK1A1 GeneID BioGRID Affinity Capture-MS
IRS1 BioGRID RNF123 GeneID BioGRID Affinity Capture-MS
IRS1 BioGRID RPTOR GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
IRS1 BioGRID FBXW11 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
IRS1 BioGRID BTRC GeneID BioGRID Affinity Capture-Western
IRS1 BioGRID CUL1 GeneID BioGRID Affinity Capture-Western
IRS1 BioGRID YWHAZ GeneID BioGRID Affinity Capture-MS
IRS1 BioGRID YWHAE GeneID BioGRID Affinity Capture-MS; Reconstituted Complex; Two-hybrid
IRS1 BioGRID ESR2 GeneID BioGRID Affinity Capture-MS
IRS1 BioGRID RNF4 GeneID BioGRID Affinity Capture-MS
IRS1 BioGRID PTPRD GeneID BioGRID Reconstituted Complex
IRS1 BioGRID EGLN3 GeneID BioGRID Affinity Capture-MS
IRS1 BioGRID AKT1 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
IRS1 BioGRID Cav2 GeneID BioGRID Affinity Capture-Western
IRS1 BioGRID Pik3r1 GeneID BioGRID Affinity Capture-Western
IRS1 BioGRID MAPK3 GeneID BioGRID Biochemical Activity
IRS1 BioGRID RPS6KB1 GeneID BioGRID Biochemical Activity; Reconstituted Complex
IRS1 BioGRID PELI1 GeneID BioGRID Two-hybrid
IRS1 BioGRID NUMB GeneID BioGRID Two-hybrid
IRS1 BioGRID PIK3R3 GeneID BioGRID Affinity Capture-Luminescence; Affinity Capture-Western; Two-hybrid
IRS1 BioGRID BCAR3 GeneID BioGRID Affinity Capture-Luminescence; Two-hybrid
IRS1 BioGRID SIRT1 GeneID BioGRID Affinity Capture-Western
IRS1 BioGRID UBC GeneID BioGRID Reconstituted Complex
IRS1 BioGRID DVL2 GeneID BioGRID Affinity Capture-Western
IRS1 BioGRID FBXO25 GeneID BioGRID Biochemical Activity
IRS1 BioGRID Sik2 GeneID BioGRID Biochemical Activity
IRS1 BioGRID PTPRU GeneID BioGRID Biochemical Activity
IRS1 BioGRID ERBB2 GeneID BioGRID Protein-peptide
IRS1 BioGRID EGFR GeneID BioGRID Protein-peptide
IRS1 BioGRID PLCG2 GeneID BioGRID Protein-peptide
IRS1 BioGRID APP GeneID BioGRID Reconstituted Complex
IRS1 BioGRID SMAD3 GeneID BioGRID Affinity Capture-MS
IRS1 BioGRID SOCS3 GeneID BioGRID Affinity Capture-Western
IRS1 BioGRID GRB10 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
IRS1 BioGRID NEDD4 GeneID BioGRID Reconstituted Complex
IRS1 BioGRID UBTF GeneID BioGRID Affinity Capture-Western
IRS1 BioGRID ESR1 GeneID BioGRID Affinity Capture-Western
IRS1 BioGRID PRKCD GeneID BioGRID Affinity Capture-Western; Biochemical Activity
IRS1 BioGRID HDAC2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
IRS1 BioGRID ALK GeneID BioGRID Affinity Capture-Western
IRS1 Protein SIK2 GeneID HPRD
IRS1 Protein PHIP GeneID HPRD
IRS1 Protein RPTOR GeneID HPRD
IRS1 Protein PIK3R3 GeneID HPRD
IRS1 Protein YWHAG GeneID HPRD
IRS1 Protein PDPK1 GeneID HPRD
IRS1 Protein YWHAE GeneID HPRD
IRS1 Protein SOCS3 GeneID HPRD
IRS1 Protein SOCS1 GeneID HPRD
IRS1 Protein IKBKB GeneID HPRD
IRS1 Protein PIK3R2 GeneID HPRD
IRS1 Protein MAPK9 GeneID HPRD
IRS1 Protein ATP2A3 GeneID HPRD
IRS1 Protein ROCK1 GeneID HPRD
IRS1 Protein GRB14 GeneID HPRD
IRS1 Protein AP3S1 GeneID HPRD
IRS1 Protein YWHAB GeneID HPRD
IRS1 Protein YWHAZ GeneID HPRD
IRS1 Protein MTOR GeneID HPRD
IRS1 Protein TUB GeneID HPRD
IRS1 Protein MAPK8 GeneID HPRD
IRS1 Protein CAV1 GeneID HPRD
IRS1 Protein GHR GeneID HPRD
IRS1 Protein PTK2 GeneID HPRD
IRS1 Protein UBTF GeneID HPRD
IRS1 Protein CHUK GeneID HPRD
IRS1 Protein SHC1 GeneID HPRD
IRS1 Protein PRKCQ GeneID HPRD
IRS1 Protein JAK3 GeneID HPRD
IRS1 Protein BCL2L1 GeneID HPRD
IRS1 Protein CDH1 GeneID HPRD
IRS1 Protein NTRK1 GeneID HPRD
IRS1 Protein FES GeneID HPRD
IRS1 Protein RAD51 GeneID HPRD
IRS1 Protein PTPRF GeneID HPRD
IRS1 Protein PRKCZ GeneID HPRD
IRS1 Protein PRKCG GeneID HPRD
IRS1 Protein PRKCD GeneID HPRD
IRS1 Protein MAPK1 GeneID HPRD
IRS1 Protein FER GeneID HPRD
IRS1 Protein TYK2 GeneID HPRD
IRS1 Protein PTPN1 GeneID HPRD
IRS1 Protein PTPN11 GeneID HPRD
IRS1 Protein PIK3R1 GeneID HPRD
IRS1 Protein CRK GeneID HPRD
IRS1 Protein AKT1 GeneID HPRD
IRS1 Protein NPM1 GeneID HPRD
IRS1 Protein PTPRC GeneID HPRD
IRS1 Protein BCR GeneID HPRD
IRS1 Protein JAK2 GeneID HPRD
IRS1 Protein JAK1 GeneID HPRD
IRS1 Protein IL4R GeneID HPRD
IRS1 Protein INSR GeneID HPRD
IRS1 Protein IRS1 GeneID HPRD
IRS1 Protein IGF1R GeneID HPRD
IRS1 Protein FYN GeneID HPRD
IRS1 Protein CSNK2B GeneID HPRD
IRS1 Protein CSNK2A1 GeneID HPRD
IRS1 Protein ATP2A2 GeneID HPRD
IRS1 Protein ATP2A1 GeneID HPRD
IRS1 Protein GRB2 GeneID HPRD
IRS1 Protein ALK GeneID HPRD
IRS1 BioGRID PTK2 GeneID BioGRID Affinity Capture-Western; Two-hybrid
IRS1 BioGRID NCK2 GeneID BioGRID Reconstituted Complex
IRS1 BioGRID NISCH GeneID BioGRID Affinity Capture-Western
IRS1 BioGRID PTPN1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
IRS1 BioGRID MAPK8 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
IRS1 BioGRID JAK3 GeneID BioGRID Affinity Capture-Western
IRS1 BioGRID JAK1 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
IRS1 BioGRID IKBKB GeneID BioGRID Affinity Capture-Western
IRS1 BioGRID AP3S1 GeneID BioGRID Reconstituted Complex
IRS1 BioGRID CHUK GeneID BioGRID Affinity Capture-Western
IRS1 BioGRID BCL2L1 GeneID BioGRID Affinity Capture-Western
IRS1 BioGRID BCL2 GeneID BioGRID Affinity Capture-Western
IRS1 BioGRID SFN GeneID BioGRID Affinity Capture-MS
IRS1 Protein SHC1 GeneID BIND Direct interaction between IRS-1 and SHC. This interaction was modeled on a demonstrated interaction between rat IRS-1 and human SHC
IRS1 Protein IGF1R GeneID BIND IGFIR interacts with IRS-1.
IRS1 Protein INSR GeneID BIND IRS-1 interacts with IR. This interaction was modeled on a demonstrated interaction between rat IRS-1 and human IR.
IRS1 Protein IGF1R GeneID BIND IRS-1 interacts with IGF-IR. This interaction was modeled on a demonstrated interaction between rat IRS-1 and human IGF-IR.
IRS1 Protein INSR GeneID BIND Insulin Receptor Substrate-1 Binds to the Insulin Receptor. This interaction is modeled on demonstrated interaction between human IR and rat IRS-1
IRS1 Protein YWHAE GeneID BIND IRS-1 interacts with 14-3-3-epsilon isoform. This interaction was modeled on a demonstrated interaction between human IRS-1 and mouse 14-3-3-epsilon isoform.
IRS1 Protein 1IRS_B Protein BIND Interaction between IL-4R Phosphopeptide (PDB ID: 1IRS_B) and IRS-1 (PDB ID: 1IRS_A).
IRS1 Protein PIK3R2 GeneID BIND IRS-1 interacts with p85-beta. This interaction was modeled based on a demonstrated interaction between IRS-1 from an unspecified species and p85-beta from an unknown species.
StringDB
A B experiments database textmining combined score hadb nhadb
IRS1 SLC2A8 0 0 240 240 1 1
IRS1 SIRT4 0 0 283 300 1 1
IRS1 CCK 0 0 167 169 1 1
IRS1 BIRC5 0 0 76 238 1 2
IRS1 GJA1 0 0 153 179 1 1
IRS1 PINK1 0 0 140 283 1 2
IRS1 TCEB2 0 0 123 162 1 1
IRS1 GSK3A 0 0 378 533 1 1
IRS1 CDC16 0 0 145 172 1 1
IRS1 PKHD1L1 0 0 0 248 1 1
IRS1 GPT 0 0 413 412 1 1
IRS1 SEPP1 0 0 167 167 1 1
IRS1 CXCL10 0 0 150 168 1 2
IRS1 RNF7 0 0 146 246 1 1
IRS1 PIKFYVE 0 0 102 154 1 2
IRS1 EIF4EBP1 0 0 664 691 1 2
IRS1 HNRNPUL2 0 0 0 168 1 1
IRS1 AXL 0 0 181 304 1 2
IRS1 FOXO4 0 0 377 413 1 1
IRS1 IPO8 0 0 66 217 1 1
IRS1 HSP90AB1 0 0 72 293 1 2
IRS1 FGF3 0 500 0 522 1 1
IRS1 ANKRD6 0 0 0 150 1 1
IRS1 PIK3R6 0 800 103 829 1 1
IRS1 GFPT2 0 0 217 235 1 1
IRS1 SYNGAP1 0 0 170 169 1 1
IRS1 MAP3K1 0 0 234 235 1 1
IRS1 IGF2R 0 0 427 443 1 1
IRS1 VLDLR 0 0 126 165 1 1
IRS1 MGAM 0 0 335 335 1 1
IRS1 ASB14 0 0 0 150 1 1
IRS1 ACVR1B 0 0 90 183 1 1
IRS1 FBXO25 270 0 0 276 1 1
IRS1 TH 0 0 134 152 1 2
IRS1 SHBG 0 0 372 372 1 1
IRS1 YES1 0 0 166 302 1 1
IRS1 RHD 0 0 160 159 1 1
IRS1 GIGYF1 0 0 326 325 1 1
IRS1 ESAM 0 0 310 309 1 1
IRS1 NGF 0 600 310 723 1 2
IRS1 DDR1 270 0 95 336 1 1
IRS1 CD34 0 0 154 153 1 2
IRS1 GYS2 0 0 235 287 1 1
IRS1 ERBB2 251 600 469 842 1 2
IRS1 BCO1 0 0 0 218 1 1
IRS1 HMGA2 0 0 195 195 1 1
IRS1 UBE2E2 0 0 155 213 1 1
IRS1 MKI67 0 0 49 151 1 2
IRS1 CSF2 0 0 160 159 1 1
IRS1 AP2M1 800 0 0 800 1 1
IRS1 DYSF 0 0 147 218 1 1
IRS1 CDC42BPA 0 0 45 216 1 1
IRS1 PPARG 0 0 734 752 1 2
IRS1 AKT1 487 0 870 960 1 2
IRS1 CPT1A 0 0 391 410 1 1
IRS1 TGFB2 0 0 112 152 1 1
IRS1 APLN 0 0 182 181 1 1
IRS1 VCAM1 0 0 325 343 1 1
IRS1 RSPO3 0 0 166 175 1 1
IRS1 NUDT12 0 0 0 150 1 1
IRS1 ATP2A3 213 0 92 254 1 1
IRS1 CD4 0 0 284 284 1 2
IRS1 ARL15 0 0 360 371 1 1
IRS1 INPP5D 0 900 138 910 1 1
IRS1 ATF4 0 0 285 284 1 2
IRS1 PRKCG 213 0 61 229 1 1
IRS1 FOXA1 0 0 140 290 1 1
IRS1 SGK3 0 0 217 401 1 1
IRS1 PRDM16 0 0 260 272 1 1
IRS1 LYPLAL1 0 0 378 378 1 1
IRS1 ANKRD30B 0 0 0 150 1 1
IRS1 KLF4 0 0 212 225 1 2
IRS1 SLC2A5 0 0 225 277 1 1
IRS1 COL1A2 0 0 112 169 1 1
IRS1 ACE2 0 0 230 250 1 2
IRS1 BMX 0 0 309 379 1 1
IRS1 ATF6 0 0 404 415 1 2
IRS1 IKBKB 462 800 766 975 1 2
IRS1 NTRK2 0 800 444 895 1 1
IRS1 COLGALT2 0 0 0 167 1 1
IRS1 PSMD8 0 0 53 187 1 1
IRS1 FGFR1 0 600 270 695 1 1
IRS1 ACACB 0 0 286 337 1 1
IRS1 COL4A2 0 0 82 305 1 1
IRS1 RUNX2 0 0 218 218 1 2
IRS1 SHC2 0 0 93 232 1 1
IRS1 PSMD5 0 0 134 152 1 1
IRS1 XIAP 0 0 203 235 1 2
IRS1 PPP2R4 0 0 464 463 1 1
IRS1 NOX4 0 0 325 325 1 2
IRS1 DROSHA 0 0 184 185 1 1
IRS1 ANKS6 0 0 0 169 1 1
IRS1 MTNR1B 0 0 469 469 1 1
IRS1 FABP2 0 0 240 257 1 1
IRS1 SLC2A12 0 0 293 324 1 1
IRS1 NRG1 0 0 119 174 1 2
IRS1 TCHP 0 0 241 240 1 1
IRS1 TBK1 0 0 120 219 1 2
IRS1 ADIPOR2 0 0 505 505 1 1
IRS1 FOXP3 0 0 155 205 1 2
IRS1 HMOX1 0 0 390 390 1 2
IRS1 PTPN6 0 900 150 912 1 1
IRS1 MGST1 0 0 0 206 1 1
IRS1 APOC2 0 0 155 154 1 1
IRS1 KDR 0 600 262 713 1 2
IRS1 DMP1 0 0 57 160 1 1
IRS1 RARRES2 0 0 293 307 1 1
IRS1 H6PD 0 0 167 167 1 1
IRS1 RRAGA 0 0 210 294 1 1
IRS1 DGKB 0 0 303 303 1 1
IRS1 IARS 0 0 294 308 1 1
IRS1 JAK1 678 900 891 996 1 2
IRS1 EIF2S1 0 0 391 390 1 2
IRS1 SKP1 0 0 233 232 1 2
IRS1 SLC13A2 0 0 0 171 1 1
IRS1 YY1 0 0 193 207 1 1
IRS1 RAC2 0 0 270 311 1 1
IRS1 A1BG 0 0 172 171 1 1
IRS1 AGTR2 0 0 175 205 1 1
IRS1 CCDC92 0 0 183 183 1 1
IRS1 MPRIP 0 0 451 463 1 1
IRS1 ADAMTSL3 0 0 140 290 1 1
IRS1 CDKAL1 0 0 508 508 1 1
IRS1 VDAC1 0 0 163 163 1 2
IRS1 TGFB1 0 0 212 252 1 2
IRS1 STAT5B 0 0 416 440 1 1
IRS1 TRRAP 0 0 61 192 1 1
IRS1 RBX1 0 0 194 312 1 1
IRS1 PIK3C2A 0 0 408 491 1 1
IRS1 TSC2 0 0 653 749 1 2
IRS1 MC4R 0 0 392 392 1 1
IRS1 LAMA3 0 0 0 154 1 1
IRS1 PRKCD 678 900 700 989 1 2
IRS1 CDKN1B 0 0 336 344 1 2
IRS1 BOLA2-SMG1P6 0 0 0 175 1 1
IRS1 TBC1D3 0 0 261 261 1 1
IRS1 DIO2 0 0 180 179 1 1
IRS1 USP7 0 0 724 765 1 1
IRS1 RB1 0 0 195 195 1 2
IRS1 PIP4K2B 0 0 0 160 1 1
IRS1 FAM155A 0 0 43 254 1 1
IRS1 SLC2A4 0 0 871 887 1 1
IRS1 FOXO3 0 0 561 849 1 2
IRS1 SPRED1 0 0 232 283 1 1
IRS1 APOE 0 0 459 462 1 2
IRS1 YWHAB 609 0 687 942 1 1
IRS1 PCSK9 0 0 202 202 1 1
IRS1 TM6SF2 0 0 229 228 1 1
IRS1 ZFPM2 0 0 141 218 1 1
IRS1 BGLAP 0 0 265 265 1 1
IRS1 DGAT2 0 0 359 376 1 1
IRS1 STAP1 0 0 431 431 1 1
IRS1 TNFSF11 0 0 180 179 1 2
IRS1 IGHMBP2 0 0 0 189 1 1
IRS1 GRAP 0 0 0 217 1 1
IRS1 IRS4 0 900 904 932 1 1
IRS1 CDC42 0 0 294 349 1 2
IRS1 SCD 0 0 458 470 1 1
IRS1 XRCC2 0 0 323 475 1 1
IRS1 DKK1 0 0 108 167 1 1
IRS1 SRC 0 500 987 994 1 2
IRS1 MPHOSPH8 0 0 0 150 1 1
IRS1 ENSG00000268465 0 0 86 171 1 1
IRS1 FBXW11 270 0 0 270 1 1
IRS1 FLT1 0 600 195 684 1 1
IRS1 TXNDC9 0 0 155 154 1 1
IRS1 COASY 0 0 193 193 1 1
IRS1 ZFAND6 0 0 156 211 1 1
IRS1 ATG3 0 0 142 161 1 2
IRS1 SLC30A8 0 0 459 465 1 1
IRS1 MIF 0 0 182 181 1 2
IRS1 LGALS3 0 0 454 454 1 2
IRS1 CDKN3 0 0 153 200 1 1
IRS1 ASB9 0 0 70 194 1 1
IRS1 ANKRD17 0 0 0 166 1 1
IRS1 KLHL13 270 0 0 270 1 1
IRS1 TP53INP1 0 0 181 195 1 2
IRS1 EWSR1 0 0 156 155 1 1
IRS1 STAT6 0 0 341 379 1 1
IRS1 ACLY 0 0 372 395 1 1
IRS1 ZBED3 0 0 241 240 1 1
IRS1 ALYREF 0 0 60 150 1 1
IRS1 EIF2AK3 0 0 517 574 1 2
IRS1 RASA3 0 0 0 195 1 1
IRS1 HNF4A 0 0 405 405 1 1
IRS1 AKIRIN1 0 0 67 209 1 1
IRS1 PPP2CA 0 0 454 454 1 1
IRS1 AHR 0 0 150 169 1 2
IRS1 SERPINE1 0 0 458 483 1 1
IRS1 PRKDC 0 0 156 274 1 2
IRS1 ETV6 0 0 140 171 1 1
IRS1 PGR 0 0 297 297 1 1
IRS1 MUC1 0 0 155 154 1 1
IRS1 EIF4E 270 0 519 689 1 2
IRS1 CDK1 0 0 194 204 1 2
IRS1 NCOR1 0 0 166 165 1 1
IRS1 YWHAQ 270 0 111 606 1 1
IRS1 ADRB2 0 0 282 282 1 1
IRS1 REM1 0 0 0 477 1 1
IRS1 AGTR1 0 0 377 390 1 1
IRS1 FCGR1A 0 0 261 261 1 1
IRS1 ANKRD18A 0 0 0 150 1 1
IRS1 RPS6KB1 487 900 852 994 1 2
IRS1 LOX 0 0 294 323 1 2
IRS1 SAG 0 0 181 198 1 1
IRS1 EPHB1 0 0 66 161 1 1
IRS1 SGK1 0 0 463 589 1 2
IRS1 IPO9 0 0 0 181 1 1
IRS1 EFS 0 0 72 151 1 1
IRS1 PIK3C2B 0 0 143 262 1 1
IRS1 CBL 486 900 456 970 1 1
IRS1 EDNRA 0 0 144 175 1 1
IRS1 SESN1 0 0 155 169 1 1
IRS1 HMGCR 0 0 323 341 1 1
IRS1 NTRK1 213 800 860 978 1 1
IRS1 MTHFR 0 0 150 188 1 1
IRS1 ATR 0 0 69 199 1 2
IRS1 DVL2 270 0 541 659 1 2
IRS1 SORBS1 0 900 190 917 1 1
IRS1 FGF5 0 500 0 499 1 1
IRS1 FAU 0 0 0 160 1 2
IRS1 ANXA2 0 0 163 163 1 1
IRS1 SPTLC2 0 0 134 161 1 1
IRS1 NCF1 0 0 217 222 1 1
IRS1 ACTN1 0 0 52 240 1 1
IRS1 WDR6 0 0 435 443 1 1
IRS1 FOXC2 0 0 155 205 1 1
IRS1 PC 0 0 245 261 1 1
IRS1 CD36 270 0 324 485 1 2
IRS1 EPHA1 0 0 113 203 1 1
IRS1 ACTA2 0 0 91 219 1 1
IRS1 FRS3 0 0 244 244 1 1
IRS1 NOS3 0 0 728 728 1 2
IRS1 PPM1K 0 0 171 260 1 1
IRS1 ANKRD37 0 0 0 150 1 1
IRS1 FLT3LG 0 500 0 499 1 1
IRS1 FSHR 0 0 290 290 1 1
IRS1 SREBF2 0 0 369 434 1 1
IRS1 PPP1R3B 0 0 261 261 1 1
IRS1 CCND1 0 0 509 549 1 2
IRS1 INS-IGF2 0 0 79 625 1 1
IRS1 ARAP1 0 0 365 378 1 1
IRS1 PRKAA1 0 0 281 399 1 2
IRS1 ARHGEF7 0 0 439 439 1 1
IRS1 RRAS2 0 0 70 226 1 1
IRS1 ATP2A2 213 0 164 366 1 1
IRS1 CTLA4 0 0 150 164 1 2
IRS1 ANKRD50 0 0 0 168 1 1
IRS1 SLC27A1 0 0 391 390 1 1
IRS1 ARHGAP5 0 0 118 151 1 1
IRS1 LDLR 0 0 335 358 1 2
IRS1 LIN28A 0 0 95 152 1 1
IRS1 GNB2L1 0 900 211 917 1 1
IRS1 KCTD15 0 0 108 169 1 1
IRS1 MDK 0 0 129 263 1 1
IRS1 ANKRD10 0 0 70 482 1 1
IRS1 MAP2K2 0 0 183 239 1 1
IRS1 BCL2 270 0 113 324 1 2
IRS1 FOXA2 0 0 261 390 1 1
IRS1 NR1D1 0 0 123 270 1 2
IRS1 PALLD 0 0 54 155 1 1
IRS1 SPRY1 0 0 218 218 1 1
IRS1 SDPR 0 0 51 208 1 1
IRS1 FGF16 0 500 0 512 1 1
IRS1 GPAM 0 0 284 301 1 1
IRS1 PHLPP2 0 0 262 292 1 1
IRS1 PTPN2 0 0 243 265 1 2
IRS1 RNASEL 0 0 128 275 1 1
IRS1 ADD1 0 0 107 172 1 1
IRS1 HPRT1 0 0 184 183 1 1
IRS1 BCAT2 0 0 246 263 1 1
IRS1 RHEB 0 0 606 722 1 2
IRS1 DDIT4 0 0 392 400 1 2
IRS1 FADS1 0 0 266 282 1 1
IRS1 POU5F1 0 0 156 155 1 2
IRS1 ENSG00000264813 0 0 401 435 1 1
IRS1 EGFL7 0 0 261 261 1 1
IRS1 LRP6 0 0 218 262 1 1
IRS1 AMY1A 0 0 0 207 1 1
IRS1 FSTL1 0 0 107 150 1 1
IRS1 MAP4K3 0 0 145 184 1 1
IRS1 STXBP3 0 0 381 395 1 1
IRS1 HGF 0 0 285 300 1 2
IRS1 BMPR2 0 0 112 202 1 1
IRS1 TXN 0 0 264 273 1 1
IRS1 CANX 0 0 167 167 1 2
IRS1 CCNE1 0 0 136 196 1 1
IRS1 MEMO1 0 0 936 936 1 1
IRS1 DMAP1 0 0 0 316 1 1
IRS1 PID1 0 0 329 329 1 1
IRS1 RASA1 0 0 241 240 1 1
IRS1 OPRM1 0 0 448 448 1 1
IRS1 DUSP6 0 0 167 213 1 1
IRS1 PDPK1 213 0 557 817 1 2
IRS1 ATP11A 0 0 67 161 1 1
IRS1 SLC27A4 0 0 218 218 1 1
IRS1 IDE 0 0 465 496 1 1
IRS1 PTK2B 0 0 670 677 1 1
IRS1 PECAM1 0 0 181 181 1 1
IRS1 CAT 0 0 455 505 1 2
IRS1 WNT10B 0 0 162 161 1 1
IRS1 GIP 0 0 340 340 1 1
IRS1 BARD1 0 0 0 150 1 1
IRS1 UBB 0 0 0 155 1 1
IRS1 HSPA2 0 0 0 158 1 1
IRS1 MYF6 0 0 143 165 1 1
IRS1 ANKRD9 0 0 0 150 1 1
IRS1 CDC42BPB 0 0 0 212 1 1
IRS1 ASB15 0 0 0 150 1 1
IRS1 NBR1 0 0 94 297 1 2
IRS1 ADAMTS9 0 0 288 288 1 1
IRS1 DNAJC6 0 0 0 242 1 1
IRS1 YBX1 0 0 95 240 1 1
IRS1 PRC1 0 0 69 180 1 1
IRS1 TNF 0 0 662 691 1 2
IRS1 NYAP1 0 0 53 258 1 1
IRS1 RNF4 270 0 0 270 1 1
IRS1 ADCY6 0 0 84 244 1 1
IRS1 MMP3 0 0 124 164 1 1
IRS1 HTR2C 0 0 82 193 1 1
IRS1 ABHD5 0 0 230 229 1 1
IRS1 UCP3 0 0 413 423 1 1
IRS1 VDR 0 0 230 229 1 2
IRS1 PIK3R2 678 800 977 999 1 1
IRS1 MEF2C 0 0 146 178 1 1
IRS1 CD44 0 0 189 189 1 2
IRS1 SLC1A5 0 0 134 168 1 1
IRS1 ANKRD1 0 0 0 150 1 1
IRS1 BDNF 0 0 390 412 1 2
IRS1 ANKRD26 0 0 306 352 1 1
IRS1 ITK 0 0 81 189 1 1
IRS1 IL7 0 600 113 630 1 1
IRS1 MC3R 0 0 146 166 1 1
IRS1 ALDH7A1 0 0 132 151 1 1
IRS1 RP1 0 0 0 254 1 1
IRS1 VCL 0 0 218 242 1 1
IRS1 ANKRD36 0 0 0 150 1 1
IRS1 LEO1 0 0 0 459 1 1
IRS1 GH1 0 900 261 923 1 1
IRS1 FIS1 0 0 150 169 1 2
IRS1 ACADM 0 0 241 240 1 1
IRS1 PAX3 0 0 122 161 1 1
IRS1 EEF2 0 0 294 317 1 2
IRS1 MLYCD 0 0 283 282 1 1
IRS1 PDGFC 0 0 211 211 1 1
IRS1 PPP1R15A 0 0 234 234 1 2
IRS1 RPLP0 0 0 117 293 1 1
IRS1 AMY2A 0 0 96 252 1 1
IRS1 ACVR2A 0 0 60 156 1 1
IRS1 OBSL1 0 0 145 236 1 1
IRS1 AP3S1 270 0 469 596 1 1
IRS1 AXIN2 0 0 142 164 1 1
IRS1 PIK3C2G 0 0 425 506 1 1
IRS1 GCG 0 0 611 611 1 1
IRS1 CMKLR1 0 0 167 167 1 1
IRS1 PTCH1 0 0 145 169 1 1
IRS1 NFKB2 0 0 113 248 1 1
IRS1 APOC3 0 0 270 270 1 1
IRS1 RND3 0 0 100 162 1 1
IRS1 SOS1 0 900 323 940 1 1
IRS1 ATG4B 0 0 103 196 1 2
IRS1 LAMC1 0 0 83 152 1 1
IRS1 TFRC 0 0 153 152 1 1
IRS1 SPRY2 0 0 234 234 1 1
IRS1 CCND2 0 0 267 273 1 1
IRS1 VWF 0 0 135 154 1 1
IRS1 CD2AP 270 0 84 302 1 1
IRS1 IGFBP6 0 0 270 295 1 1
IRS1 RPS6KA2 0 0 276 304 1 1
IRS1 MAP4K1 0 0 150 182 1 1
IRS1 AGT 0 0 218 403 1 1
IRS1 ASB11 0 0 0 150 1 1
IRS1 TXNIP 0 0 287 286 1 2
IRS1 PRLR 0 650 451 843 1 1
IRS1 PROX1 0 0 162 178 1 1
IRS1 BCL2A1 0 0 166 165 1 1
IRS1 CSNK2A1 213 0 104 264 1 1
IRS1 THNSL2 0 0 108 169 1 1
IRS1 FGF2 0 500 292 640 1 2
IRS1 ANKRD62 0 0 0 150 1 1
IRS1 ATF3 0 0 170 169 1 2
IRS1 PPP2R5C 0 0 113 199 1 1
IRS1 EXOC3L2 0 0 86 155 1 1
IRS1 TUBGCP6 0 0 0 171 1 1
IRS1 CDH5 0 0 122 156 1 1
IRS1 RETN 0 0 606 633 1 1
IRS1 GADD45A 0 0 134 180 1 1
IRS1 CNR1 0 0 218 218 1 1
IRS1 EPHB4 0 0 72 187 1 1
IRS1 PKM 0 0 231 244 1 1
IRS1 ARNTL 0 0 180 179 1 1
IRS1 SOCS1 746 900 677 991 1 1
IRS1 FABP1 0 0 213 230 1 1
IRS1 TAF5 0 0 0 158 1 1
IRS1 BTK 0 0 213 293 1 1
IRS1 NEDD4L 0 0 106 179 1 1
IRS1 MERTK 0 0 97 207 1 1
IRS1 CCND3 0 0 146 188 1 1
IRS1 CSF1R 0 600 141 641 1 1
IRS1 CYTH3 270 0 137 446 1 1
IRS1 APOB 0 0 459 471 1 2
IRS1 UVRAG 0 0 114 195 1 2
IRS1 SOCS4 0 600 559 816 1 1
IRS1 MAPK1 213 900 483 960 1 2
IRS1 PPP2R1A 0 0 66 217 1 1
IRS1 IGF1 0 900 977 997 1 2
IRS1 CCDC144A 0 0 0 150 1 1
IRS1 ESPN 0 0 0 209 1 1
IRS1 TSPAN8 0 0 253 252 1 1
IRS1 PPFIBP1 0 0 0 181 1 1
IRS1 TGFBR1 0 0 181 264 1 1
IRS1 MST1R 0 0 123 212 1 1
IRS1 SOCS6 0 0 362 362 1 1
IRS1 MGLL 0 0 183 183 1 1
IRS1 DYRK1A 270 0 136 356 1 1
IRS1 WISP3 0 0 174 173 1 1
IRS1 VAV1 0 0 181 181 1 1
IRS1 ADRB1 0 0 124 186 1 1
IRS1 HSPB1 0 0 290 290 1 2
IRS1 GLI1 0 0 194 213 1 2
IRS1 HADHB 0 0 95 162 1 1
IRS1 HSPB2 0 0 260 266 1 1
IRS1 UBC 270 0 90 390 1 2
IRS1 AGFG1 0 0 90 155 1 1
IRS1 MAMDC4 0 0 66 161 1 1
IRS1 TEAD4 0 0 113 154 1 1
IRS1 MAP1LC3B 0 0 248 253 1 2
IRS1 PTPRR 0 0 120 168 1 1
IRS1 KPTN 0 0 0 207 1 1
IRS1 NFKBIB 0 0 113 299 1 1
IRS1 COL4A6 0 0 0 230 1 1
IRS1 ADAM17 0 0 195 195 1 1
IRS1 RPS6KA1 0 0 494 511 1 1
IRS1 ELANE 0 0 266 266 1 1
IRS1 PRKCA 0 0 686 686 1 1
IRS1 CYTH2 270 0 71 358 1 1
IRS1 RIPK4 0 0 0 202 1 1
IRS1 TENM3 0 0 0 229 1 1
IRS1 ULK1 0 0 301 341 1 2
IRS1 TBP 0 0 159 160 1 1
IRS1 FN1 0 900 336 934 1 2
IRS1 FBXO40 0 0 392 501 1 1
IRS1 RALA 0 0 136 183 1 1
IRS1 IKBKG 0 800 486 892 1 1
IRS1 MAP4K4 0 0 210 210 1 1
IRS1 RARS 0 0 66 203 1 1
IRS1 MUSK 0 0 135 266 1 1
IRS1 RAD51B 0 0 123 328 1 1
IRS1 GPX1 0 0 233 253 1 1
IRS1 MMP13 0 0 124 156 1 2
IRS1 NEDD1 0 0 0 169 1 1
IRS1 AKT3 0 0 464 697 1 2
IRS1 CSNK2B 462 0 47 522 1 1
IRS1 KHK 0 0 204 210 1 1
IRS1 NOX1 0 0 167 167 1 1
IRS1 LMNB1 0 0 81 198 1 1
IRS1 ACOX1 0 0 282 303 1 1
IRS1 PRL 0 650 380 773 1 1
IRS1 UBTF 486 0 824 910 1 1
IRS1 SIRT1 486 0 738 883 1 2
IRS1 PLIN2 0 0 282 290 1 2
IRS1 NUAK1 0 0 95 165 1 1
IRS1 DLK1 0 0 193 193 1 1
IRS1 MCL1 0 0 260 260 1 2
IRS1 MAP3K5 0 0 391 391 1 1
IRS1 BACE1 0 0 294 294 1 2
IRS1 PDK4 0 0 420 453 1 1
IRS1 ITGAM 0 0 211 211 1 1
IRS1 LYN 0 0 209 290 1 1
IRS1 PIM2 0 0 95 154 1 1
IRS1 ESR1 270 0 961 971 1 2
IRS1 IFNB1 0 0 167 167 1 1
IRS1 IRF5 0 0 370 370 1 1
IRS1 NCL 0 0 807 835 1 2
IRS1 ADCY8 0 0 128 192 1 1
IRS1 HMGB1 0 0 157 156 1 2
IRS1 RAC1 0 0 150 184 1 2
IRS1 MAP2K6 0 0 150 168 1 1
IRS1 KSR1 0 0 123 212 1 1
IRS1 ATG5 0 0 259 268 1 2
IRS1 YIPF1 0 0 264 264 1 1
IRS1 MT-ND1 0 0 49 254 1 1
IRS1 C2CD4B 0 0 292 292 1 1
IRS1 WNT3A 0 0 234 261 1 2
IRS1 ANKRD22 0 0 0 150 1 1
IRS1 SYP 0 0 928 928 1 1
IRS1 PRKD1 0 900 193 917 1 1
IRS1 LRRC57 0 0 0 183 1 1
IRS1 LGR5 0 0 134 193 1 1
IRS1 ITGB3 0 900 413 946 1 1
IRS1 YAP1 0 0 827 850 1 2
IRS1 STAT2 0 0 134 298 1 1
IRS1 TANC2 0 0 0 150 1 1
IRS1 XBP1 0 0 459 471 1 2
IRS1 ASB3 0 0 0 150 1 1
IRS1 RAD51D 0 0 142 291 1 1
IRS1 PTPN1 487 900 788 988 1 1
IRS1 MIB1 0 0 0 405 1 1
IRS1 HSBP1 0 0 0 250 1 1
IRS1 APOA5 0 0 193 193 1 1
IRS1 PRKAG2 0 0 162 180 1 1
IRS1 VEGFA 0 0 504 514 1 2
IRS1 SLC2A14 0 0 427 465 1 1
IRS1 MAPK7 0 0 322 346 1 1
IRS1 PTEN 0 0 653 844 1 2
IRS1 RHBDD1 0 0 82 459 1 1
IRS1 BMPR1A 0 0 73 184 1 1
IRS1 ENOPH1 0 0 0 224 1 1
IRS1 GAPDHS 0 0 0 207 1 1
IRS1 MYOD1 0 0 329 333 1 1
IRS1 DNM1L 0 0 195 195 1 2
IRS1 PPFIBP2 0 0 0 163 1 1
IRS1 NTRK3 0 800 833 968 1 1
IRS1 RRAGB 0 0 234 315 1 1
IRS1 PI4KB 0 0 0 193 1 1
IRS1 PRKAA2 0 0 234 334 1 2
IRS1 FFAR4 0 0 300 301 1 1
IRS1 LDHA 0 0 134 153 1 2
IRS1 BMP4 0 0 157 182 1 1
IRS1 LOC110117498-PIK3R3 0 0 0 748 1 1
IRS1 PTRF 0 0 143 213 1 1
IRS1 LEP 0 600 729 898 1 1
IRS1 SYK 0 0 181 264 1 2
IRS1 KIT 0 600 248 686 1 2
IRS1 NFKBIA 0 0 467 543 1 2
IRS1 EIF4EBP3 0 0 81 156 1 1
IRS1 CFL1 0 0 165 165 1 1
IRS1 MGEA5 0 0 184 257 1 1
IRS1 TIMP3 0 0 150 189 1 1
IRS1 LMNB2 0 0 52 173 1 1
IRS1 MAPK14 0 0 325 448 1 2
IRS1 NGFR 0 600 151 645 1 1
IRS1 E2F3 0 0 170 169 1 1
IRS1 TP53BP2 0 0 383 474 1 2
IRS1 MARK2 0 0 170 169 1 1
IRS1 MAPK10 0 800 285 877 1 2
IRS1 SLC27A2 0 0 150 169 1 1
IRS1 SREBF1 0 0 681 713 1 1
IRS1 UCP1 0 0 505 516 1 2
IRS1 TYRO3 0 0 102 205 1 1
IRS1 RAB41 0 0 0 173 1 1
IRS1 IGF2 0 600 654 866 1 1
IRS1 CTSD 0 0 170 169 1 2
IRS1 AXIN1 0 0 242 241 1 1
IRS1 EIF3F 0 0 180 189 1 1
IRS1 TRIM63 0 0 413 422 1 1
IRS1 PON2 0 0 155 154 1 1
IRS1 EZR 0 0 112 173 1 1
IRS1 ANKRD18B 0 0 0 150 1 1
IRS1 SHC1 213 900 963 997 1 1
IRS1 ENSG00000278299 0 0 260 260 1 1
IRS1 ATM 0 0 618 621 1 2
IRS1 TEAD1 0 0 66 169 1 1
IRS1 PRKAG3 0 0 141 293 1 1
IRS1 UNG 0 0 0 181 1 1
IRS1 RET 0 900 218 918 1 1
IRS1 LCAT 0 0 152 151 1 1
IRS1 G6PD 0 0 268 276 1 1
IRS1 AGRP 0 0 403 403 1 1
IRS1 CSRP3 0 0 0 212 1 1
IRS1 ENG 0 0 74 326 1 2
IRS1 CCL3 0 0 159 158 1 1
IRS1 OGT 0 800 260 847 1 2
IRS1 MDM4 0 0 108 197 1 1
IRS1 TTI1 0 0 159 177 1 1
IRS1 GOT2 0 0 293 303 1 1
IRS1 RXRG 0 0 105 160 1 1
IRS1 SELE 0 0 181 204 1 1
IRS1 TJP1 0 0 180 214 1 1
IRS1 DMD 0 0 123 210 1 2
IRS1 TGFBR2 0 0 163 248 1 1
IRS1 TRAT1 0 0 156 155 1 1
IRS1 ATG7 0 0 264 283 1 2
IRS1 ANKRD20A3 0 0 0 150 1 1
IRS1 WNT10A 0 0 113 153 1 1
IRS1 DLG4 0 0 212 216 1 2
IRS1 PREX1 0 0 454 454 1 1
IRS1 ACTG1 0 0 151 184 1 1
IRS1 FAIM2 0 0 124 160 1 1
IRS1 NR1H4 0 0 255 254 1 1
IRS1 WDR7 0 0 67 161 1 1
IRS1 GFRA1 0 900 43 904 1 1
IRS1 HHEX 0 0 379 379 1 1
IRS1 GRK6 0 0 88 232 1 1
IRS1 NCK1 0 0 819 819 1 1
IRS1 CPT1C 0 0 254 266 1 1
IRS1 SNAI1 0 0 195 195 1 1
IRS1 IL10 0 0 392 404 1 2
IRS1 FGFR4 0 600 141 641 1 1
IRS1 ARVCF 0 0 0 154 1 1
IRS1 NPM1 213 0 204 355 1 1
IRS1 NAMPT 0 0 423 449 1 2
IRS1 PPARGC1B 0 0 218 298 1 1
IRS1 FLT3 0 600 112 629 1 2
IRS1 PTPRF 462 800 233 915 1 1
IRS1 PTK7 0 0 0 160 1 1
IRS1 IRAK4 0 0 81 247 1 1
IRS1 COL1A1 0 0 134 209 1 2
IRS1 YWHAH 609 0 55 766 1 1
IRS1 AHSG 0 0 304 304 1 1
IRS1 LRCH4 0 0 0 298 1 1
IRS1 CDC123 0 0 322 321 1 1
IRS1 HDAC1 0 0 445 489 1 2
IRS1 MAP3K10 0 0 107 198 1 1
IRS1 RIPK1 0 0 96 188 1 2
IRS1 CSF1 0 0 150 185 1 1
IRS1 FLOT2 0 0 81 419 1 1
IRS1 GHR 213 900 391 949 1 1
IRS1 FBP1 0 0 156 162 1 1
IRS1 HCK 0 0 123 212 1 1
IRS1 PI4KA 0 0 0 175 1 1
IRS1 SMPD1 0 0 150 168 1 1
IRS1 FGF9 0 500 57 523 1 1
IRS1 RASA2 0 0 0 195 1 1
IRS1 CEBPB 0 0 391 406 1 2
IRS1 TBC1D7 0 0 234 234 1 2
IRS1 PIK3CD 0 800 495 942 1 1
IRS1 INPP4B 0 0 195 212 1 1
IRS1 MEF2A 0 0 150 168 1 1
IRS1 NEU3 0 0 143 176 1 1
IRS1 PEPD 0 0 253 252 1 1
IRS1 NTF3 0 600 102 640 1 1
IRS1 RBL2 0 0 108 152 1 1
IRS1 INSRR 0 540 310 835 1 1
IRS1 WNT2 0 0 94 294 1 1
IRS1 RIN1 0 0 357 357 1 1
IRS1 EPHB2 0 0 57 153 1 2
IRS1 CHUK 270 800 494 929 1 1
IRS1 CUL3 270 0 124 333 1 2
IRS1 ANGPTL3 0 0 150 173 1 1
IRS1 AGPAT2 0 0 157 156 1 1
IRS1 ANKRD29 0 0 0 177 1 1
IRS1 ANKS4B 0 0 0 150 1 1
IRS1 PDE3B 0 0 423 422 1 1
IRS1 PNPLA3 0 0 322 358 1 1
IRS1 ADAMTSL1 0 0 0 235 1 1
IRS1 JAZF1 0 0 336 336 1 1
IRS1 ARRB2 0 0 193 223 1 1
IRS1 BMPR1B 0 0 57 153 1 1
IRS1 CAPN10 0 0 500 499 1 2
IRS1 CALM2 0 0 0 153 1 1
IRS1 SOCS2 0 600 402 750 1 1
IRS1 GK 0 0 150 188 1 1
IRS1 SST 0 0 282 283 1 1
IRS1 CDKN2A 0 0 361 434 1 2
IRS1 SFN 63 0 81 348 1 2
IRS1 GUSB 0 0 113 239 1 1
IRS1 FABP4 0 0 459 473 1 1
IRS1 EPHA3 0 0 57 153 1 1
IRS1 TBC1D1 0 0 395 416 1 1
IRS1 GPX8 0 0 0 243 1 1
IRS1 FGF8 0 500 0 520 1 1
IRS1 ARRB1 0 0 193 331 1 1
IRS1 XRCC5 0 0 159 182 1 1
IRS1 TTR 0 0 164 163 1 1
IRS1 GSK3B 270 0 520 759 1 2
IRS1 SIK1 0 0 181 198 1 1
IRS1 MRC1 0 0 193 193 1 1
IRS1 ITGAX 0 0 213 213 1 1
IRS1 BLK 0 0 113 226 1 1
IRS1 EIF3A 0 0 448 448 1 1
IRS1 VEGFC 0 0 180 220 1 1
IRS1 LMNTD2 0 0 0 163 1 1
IRS1 CYBB 0 0 266 266 1 2
IRS1 PRR5L 0 0 137 156 1 1
IRS1 ENSG00000268643 0 0 0 281 1 1
IRS1 PTS 0 0 395 394 1 1
IRS1 ASZ1 0 0 0 150 1 1
IRS1 ANKRD63 0 0 0 150 1 1
IRS1 PPIA 0 0 183 183 1 1
IRS1 TRPC4 0 0 226 226 1 1
IRS1 NOTCH2 0 0 173 192 1 1
IRS1 ACE 0 0 406 449 1 1
IRS1 FGF22 0 500 0 522 1 1
IRS1 ALOX5 0 0 154 206 1 1
IRS1 BCAR1 0 900 263 926 1 1
IRS1 REN 0 0 452 486 1 1
IRS1 PRKCQ 213 800 361 906 1 2
IRS1 TONSL 0 0 0 150 1 1
IRS1 ATG12 0 0 193 194 1 2
IRS1 ASAH1 0 0 146 179 1 1
IRS1 IL13 0 0 266 266 1 2
IRS1 LIPC 0 0 181 181 1 1
IRS1 HADH 0 0 181 227 1 1
IRS1 EIF4B 0 0 339 380 1 1
IRS1 ENPP1 0 0 391 390 1 1
IRS1 AFP 0 0 155 199 1 2
IRS1 TUB 213 0 56 225 1 1
IRS1 LTK 0 0 491 544 1 1
IRS1 TBC1D3D 0 0 255 254 1 1
IRS1 LIMK1 0 0 112 207 1 1
IRS1 NYAP2 0 0 268 343 1 1
IRS1 PTGS2 0 0 358 369 1 2
IRS1 FGF19 0 500 91 545 1 1
IRS1 GAPVD1 0 0 107 166 1 1
IRS1 RPSA 0 0 262 267 1 1
IRS1 ERBB3 0 600 571 830 1 1
IRS1 CASP3 0 0 505 516 1 2
IRS1 NQO1 0 0 195 195 1 2
IRS1 F3 0 0 167 185 1 1
IRS1 PLIN3 0 0 145 164 1 1
IRS1 CXCL1 0 0 161 167 1 2
IRS1 IL33 0 0 134 170 1 2
IRS1 TRIB3 0 0 296 296 1 2
IRS1 GFPT1 0 0 206 215 1 1
IRS1 HSPA1B 0 0 0 164 1 1
IRS1 BRCA2 0 0 170 256 1 1
IRS1 NLRP3 0 0 323 323 1 2
IRS1 LNX1 0 0 0 237 1 1
IRS1 REL 0 0 167 167 1 2
IRS1 KLF14 0 0 390 414 1 1
IRS1 CAV3 0 0 202 249 1 1
IRS1 PPP1R3A 0 0 180 202 1 1
IRS1 ASB8 0 0 0 150 1 1
IRS1 ADCY3 0 0 112 177 1 1
IRS1 ZDHHC18 270 0 0 270 1 1
IRS1 LPIN1 0 0 391 405 1 2
IRS1 IKBIP 0 0 0 200 1 1
IRS1 GLIS3 0 0 218 231 1 1
IRS1 ENSG00000267618 0 0 142 291 1 1
IRS1 RRAGD 0 0 218 235 1 1
IRS1 ACADVL 0 0 143 376 1 1
IRS1 CILP2 0 0 167 167 1 1
IRS1 AMY2B 0 0 0 207 1 1
IRS1 TAOK1 0 0 96 252 1 1
IRS1 PIK3CB 486 800 755 984 1 1
IRS1 TLR2 0 0 269 270 1 2
IRS1 CERS6 0 0 172 171 1 1
IRS1 CDKN2B 0 0 195 287 1 1
IRS1 MAPK11 0 0 122 256 1 1
IRS1 PEA15 0 0 107 159 1 1
IRS1 FLT4 0 600 136 668 1 1
IRS1 DUSP1 0 0 233 275 1 1
IRS1 FGF23 0 500 94 531 1 1
IRS1 IPO7 0 0 0 153 1 1
IRS1 SLC5A2 0 0 287 303 1 1
IRS1 MET 0 600 707 893 1 2
IRS1 PHB 0 0 125 268 1 1
IRS1 TRAF3 0 0 134 153 1 2
IRS1 LRRK2 128 0 74 270 1 2
IRS1 CDKN2C 0 0 65 172 1 1
IRS1 THBS1 0 0 181 201 1 1
IRS1 SLC16A11 0 0 150 161 1 1
IRS1 CYP11A1 0 0 157 158 1 1
IRS1 SHC4 0 0 0 188 1 1
IRS1 MAPT 0 0 371 371 1 2
IRS1 BECN1 0 0 958 960 1 2
IRS1 LRP1 0 0 150 192 1 1
IRS1 EIF4EBP2 0 0 260 570 1 1
IRS1 EEF2K 0 0 255 273 1 2
IRS1 GYS1 0 0 377 377 1 1
IRS1 TLR6 0 0 88 183 1 1
IRS1 PHIP 213 0 829 879 1 1
IRS1 IL2 0 900 241 920 1 1
IRS1 OLR1 0 0 134 153 1 2
IRS1 SUFU 0 0 81 244 1 1
IRS1 FOXO1 0 0 743 753 1 2
IRS1 TPTE2 0 0 48 248 1 1
IRS1 SH2B1 499 600 685 958 1 1
IRS1 KRAS 0 900 392 956 1 2
IRS1 ASB2 0 0 0 150 1 1
IRS1 ADRBK1 0 0 959 961 1 1
IRS1 THEM4 0 0 154 153 1 1
IRS1 PTH 0 0 241 240 1 1
IRS1 SOD2 0 0 297 367 1 2
IRS1 E2F1 0 0 161 180 1 2
IRS1 HSPA5 0 0 394 410 1 2
IRS1 FGF20 0 500 0 508 1 1
IRS1 CHMP5 0 0 0 248 1 1
IRS1 NRAS 0 900 171 930 1 1
IRS1 BTRC 270 0 113 330 1 1
IRS1 EIF4A2 0 0 211 211 1 1
IRS1 MLST8 0 900 525 950 1 1
IRS1 MTPN 0 0 142 621 1 1
IRS1 LNX2 0 0 0 192 1 1
IRS1 ASB5 0 0 0 150 1 1
IRS1 RXRA 0 0 171 268 1 1
IRS1 G6PC2 0 0 181 360 1 1
IRS1 PKP4 0 0 0 158 1 1
IRS1 TCEB1 0 0 113 153 1 1
IRS1 ANGPTL4 0 0 188 210 1 1
IRS1 STAT5A 0 0 403 428 1 1
IRS1 GAB1 0 500 404 683 1 1
IRS1 PON1 0 0 209 209 1 1
IRS1 DDAH1 0 0 123 155 1 1
IRS1 PTPN11 973 900 989 999 1 1
IRS1 MYO1C 0 0 124 151 1 1
IRS1 IRAK3 0 0 54 150 1 1
IRS1 SUCLG2 0 0 266 273 1 1
IRS1 MSTN 0 0 409 425 1 1
IRS1 DEPTOR 0 0 470 491 1 2
IRS1 PDX1 0 0 327 336 1 1
IRS1 CRKL 0 900 245 930 1 1
IRS1 RRAGC 0 0 261 274 1 1
IRS1 SHB 0 0 162 202 1 1
IRS1 FASLG 0 0 187 187 1 1
IRS1 FOS 0 0 392 392 1 2
IRS1 GHSR 0 0 204 242 1 1
IRS1 TWIST1 0 0 150 183 1 1
IRS1 YWHAZ 462 0 672 916 1 1
IRS1 PTK6 0 0 269 344 1 2
IRS1 ANKRD32 0 0 0 150 1 1
IRS1 CAPSL 0 0 150 151 1 1
IRS1 SOCS3 462 900 913 994 1 1
IRS1 GAS7 0 0 308 319 1 1
IRS1 DHX9 0 0 46 221 1 1
IRS1 BCKDHB 0 0 0 189 1 1
IRS1 P3R3URF 0 0 0 693 1 1
IRS1 HSD11B1 0 0 258 285 1 1
IRS1 IFNG 0 0 218 266 1 2
IRS1 KHDRBS1 695 0 662 897 1 1
IRS1 IL2RB 0 900 0 900 1 1
IRS1 RAPGEF3 0 0 146 164 1 1
IRS1 CIDEC 0 0 261 277 1 1
IRS1 CREB1 0 0 505 517 1 2
IRS1 USP9X 270 0 0 283 1 1
IRS1 PLCG2 275 0 88 410 1 1
IRS1 PIN4 0 0 425 425 1 1
IRS1 CCL5 0 0 206 206 1 2
IRS1 ESRRA 0 0 151 150 1 1
IRS1 GRB10 486 900 688 985 1 1
IRS1 CYP17A1 0 0 156 157 1 1
IRS1 KCNJ11 0 0 504 504 1 1
IRS1 TENC1 0 0 270 423 1 1
IRS1 RECK 0 0 123 157 1 1
IRS1 PFKFB3 0 0 171 171 1 2
IRS1 CREBBP 0 0 194 209 1 1
IRS1 DGCR8 0 0 155 154 1 1
IRS1 IGFBP5 0 0 401 436 1 1
IRS1 GCKR 0 0 278 280 1 1
IRS1 ANKRD20A1 0 0 0 150 1 1
IRS1 HSPA1L 0 0 0 164 1 1
IRS1 TRIP12 0 0 74 156 1 1
IRS1 IL4R 420 900 167 947 1 1
IRS1 SIRT2 0 0 321 337 1 2
IRS1 SCAP 0 0 172 189 1 1
IRS1 CUL7 486 0 861 927 1 1
IRS1 EPO 0 0 209 209 1 2
IRS1 TANC1 0 0 0 150 1 1
IRS1 IST1 0 0 119 352 1 1
IRS1 PLK1 0 0 166 165 1 2
IRS1 FAM13A 0 0 339 353 1 1
IRS1 IQGAP1 0 0 494 494 1 1
IRS1 FGF21 0 0 452 452 1 2
IRS1 FTO 0 0 518 518 1 2
IRS1 CS 0 0 261 266 1 1
IRS1 ANXA5 0 0 253 267 1 2
IRS1 INPPL1 0 0 402 419 1 1
IRS1 CCNB1 0 0 184 235 1 1
IRS1 HSD11B2 0 0 112 202 1 1
IRS1 ANKRD20A2 0 0 0 150 1 1
IRS1 FOXM1 0 0 290 317 1 1
IRS1 FBXO32 0 0 468 489 1 2
IRS1 RPS3 0 0 47 187 1 1
IRS1 CTNND1 0 0 96 245 1 1
IRS1 SLC5A4 0 0 284 284 1 1
IRS1 TEC 0 0 0 164 1 1
IRS1 AFF3 0 0 0 200 1 1
IRS1 MAPK8IP1 0 0 328 342 1 1
IRS1 TRIM72 675 0 696 900 1 1
IRS1 NFKB1 0 0 150 294 1 2
IRS1 PPP1R12B 0 0 74 254 1 1
IRS1 STRADA 0 0 142 255 1 1
IRS1 RELA 0 0 186 191 1 2
IRS1 BCL2L1 270 0 519 634 1 2
IRS1 GNRHR 0 0 0 212 1 1
IRS1 IGF2BP2 0 0 465 465 1 1
IRS1 PIK3R4 0 600 172 654 1 2
IRS1 ACSS2 0 0 141 180 1 1
IRS1 KITLG 0 0 137 162 1 1
IRS1 PHLPP1 0 0 380 405 1 2
IRS1 ZDHHC23 270 0 0 270 1 1
IRS1 STAT4 0 0 87 272 1 1
IRS1 ZAP70 0 0 122 223 1 1
IRS1 RAN 0 0 0 173 1 2
IRS1 FKBP8 0 0 229 228 1 1
IRS1 APOA1 0 0 280 282 1 1
IRS1 GABARAPL2 0 0 143 194 1 2
IRS1 RPS6KA5 0 0 107 162 1 1
IRS1 TCF7L2 0 0 564 564 1 1
IRS1 SMG1 0 0 92 219 1 1
IRS1 PRR5 0 0 336 336 1 1
IRS1 NOS2 0 0 216 233 1 2
IRS1 MAP2K7 0 0 560 565 1 1
IRS1 ABL1 0 0 234 327 1 1
IRS1 NF1 0 0 181 204 1 1
IRS1 FGFR2 0 600 167 660 1 1
IRS1 SH2B3 0 0 181 181 1 1
IRS1 SMAD2 0 0 291 296 1 2
IRS1 KSR2 0 0 61 157 1 1
IRS1 EMR1 0 0 66 169 1 1
IRS1 TLR4 0 0 470 503 1 2
IRS1 AGFG2 0 0 47 210 1 1
IRS1 GAPDH 0 0 561 563 1 2
IRS1 DUSP5 0 0 143 190 1 1
IRS1 ATG14 0 0 162 161 1 2
IRS1 NDRG1 0 0 161 161 1 1
IRS1 KCNQ1 0 0 393 392 1 1
IRS1 RAB6B 0 0 0 173 1 1
IRS1 PIR 0 0 505 515 1 1
IRS1 CXCL8 0 0 391 390 1 2
IRS1 KIAA1429 270 0 0 270 1 1
IRS1 DDOST 0 0 155 154 1 1
IRS1 NFKBID 0 0 0 150 1 1
IRS1 SULF2 0 0 0 183 1 1
IRS1 GAREM 0 0 112 155 1 1
IRS1 ARF3 0 0 183 197 1 1
IRS1 IL6R 0 0 193 193 1 1
IRS1 RQCD1 0 0 0 181 1 1
IRS1 SLC1A7 0 0 234 234 1 1
IRS1 HIF1A 0 0 452 476 1 2
IRS1 EDN1 0 0 460 493 1 1
IRS1 GCK 0 0 602 604 1 1
IRS1 NEDD4 0 0 204 234 1 2
IRS1 PYGL 0 0 90 186 1 1
IRS1 SIRT5 0 0 279 312 1 1
IRS1 PRKCB 0 800 338 861 1 2
IRS1 RAB5A 0 0 459 459 1 2
IRS1 FAT1 0 0 95 190 1 1
IRS1 IL1B 0 0 561 562 1 2
IRS1 ANKRD23 0 0 0 150 1 1
IRS1 HIF3A 0 0 155 154 1 1
IRS1 NR1H3 0 0 245 295 1 1
IRS1 SP1 0 0 181 194 1 2
IRS1 ASB18 0 0 0 150 1 1
IRS1 WNT2B 0 0 81 179 1 1
IRS1 PASK 270 0 0 350 1 1
IRS1 IKBKE 0 0 73 197 1 1
IRS1 PRKAG1 0 0 125 188 1 1
IRS1 PACS2 0 0 67 170 1 1
IRS1 SH2B2 0 900 433 964 1 1
IRS1 TENM2 0 0 0 184 1 1
IRS1 CDK2 0 0 293 309 1 2
IRS1 SOCS7 0 0 421 451 1 1
IRS1 CTNNB1 0 0 962 969 1 2
IRS1 MYF5 0 0 219 219 1 1
IRS1 HRAS 0 900 460 958 1 2
IRS1 MAP1LC3A 0 0 120 182 1 2
IRS1 KLHL9 270 0 0 270 1 1
IRS1 LIPE 0 0 556 556 1 1
IRS1 GALNT10 0 0 90 186 1 1
IRS1 APP 0 0 455 484 1 2
IRS1 MFN2 0 0 204 204 1 2
IRS1 EPHA2 0 600 133 719 1 1
IRS1 EGR1 0 0 261 273 1 2
IRS1 RAD51 270 0 987 991 1 2
IRS1 MTOR 675 900 827 994 1 2
IRS1 MAPKAP1 0 0 336 451 1 1
IRS1 ANKS3 0 0 0 150 1 1
IRS1 CARS 0 0 0 298 1 1
IRS1 PSMC6 0 0 322 321 1 1
IRS1 CALM1 0 0 108 279 1 1
IRS1 BCAR3 170 0 73 214 1 1
IRS1 PTPRU 270 0 0 309 1 1
IRS1 POTEF 0 0 133 226 1 1
IRS1 ANKRD52 0 0 0 171 1 1
IRS1 HELQ 0 0 0 150 1 1
IRS1 PSEN2 0 0 147 165 1 1
IRS1 FGF13 0 0 195 195 1 1
IRS1 CYR61 0 0 134 185 1 1
IRS1 CXCR4 0 0 186 186 1 2
IRS1 STAP2 0 0 251 250 1 1
IRS1 ARAF 0 0 167 257 1 1
IRS1 EEF1B2 0 0 0 189 1 1
IRS1 PTPN13 0 0 265 299 1 1
IRS1 NOTCH1 0 0 293 293 1 2
IRS1 STAT1 0 0 340 384 1 2
IRS1 SOCS5 0 0 324 328 1 1
IRS1 RTF1 0 0 0 189 1 1
IRS1 FOXO6 0 0 218 265 1 1
IRS1 RAD51C 0 0 138 301 1 1
IRS1 PLEK 0 0 603 621 1 1
IRS1 TNFRSF1A 0 0 287 304 1 1
IRS1 RPS6 0 0 528 576 1 2
IRS1 MYOG 0 0 324 325 1 1
IRS1 ACTN4 0 0 454 454 1 1
IRS1 ENSG00000115239 0 0 0 150 1 1
IRS1 NPHS1 0 0 162 162 1 1
IRS1 MPO 0 0 193 193 1 2
IRS1 SUMO4 0 0 151 150 1 1
IRS1 PRKG1 0 0 210 245 1 1
IRS1 PIK3C3 0 600 320 756 1 2
IRS1 PLIN1 0 0 420 433 1 1
IRS1 BRWD3 0 0 0 151 1 1
IRS1 PPP1R12A 0 0 851 860 1 1
IRS1 UCP2 0 0 493 503 1 2
IRS1 DOK2 0 0 171 193 1 1
IRS1 IL6 0 0 665 680 1 2
IRS1 ABHD12 0 0 0 179 1 1
IRS1 EFHB 0 0 202 203 1 1
IRS1 IGFBP7 0 0 211 228 1 1
IRS1 SLC2A1 0 0 651 674 1 2
IRS1 MOGAT1 0 0 139 191 1 1
IRS1 ANKFY1 0 0 0 150 1 1
IRS1 FGFR3 0 600 157 656 1 1
IRS1 LACTB 0 0 293 293 1 1
IRS1 RAB4A 0 0 171 185 1 1
IRS1 FFAR1 0 0 286 287 1 1
IRS1 FADD 0 0 134 157 1 2
IRS1 FES 213 0 119 353 1 1
IRS1 HTT 0 0 171 188 1 2
IRS1 MYD88 0 0 253 252 1 2
IRS1 PPP1CC 0 0 161 161 1 1
IRS1 CDK4 0 0 286 305 1 2
IRS1 EGFR 251 600 865 961 1 2
IRS1 CFLAR 0 0 142 160 1 2
IRS1 PRKCI 0 0 65 383 1 1
IRS1 MDM2 0 0 492 563 1 2
IRS1 TP53 0 0 519 599 1 2
IRS1 LCN2 0 0 160 159 1 1
IRS1 HMGCS1 0 0 170 176 1 1
IRS1 PRKCE 0 800 241 847 1 1
IRS1 INSIG1 0 0 320 319 1 1
IRS1 CFTR 0 0 129 219 1 2
IRS1 TNS3 0 0 56 254 1 1
IRS1 SLC7A5 0 0 202 202 1 1
IRS1 GKAP1 0 0 481 486 1 1
IRS1 PNLIP 0 0 157 170 1 1
IRS1 APBB1IP 0 0 0 282 1 1
IRS1 HDAC2 270 0 838 890 1 1
IRS1 MAP3K7 0 0 170 255 1 2
IRS1 DDIT3 0 0 338 342 1 2
IRS1 RAB10 0 0 218 218 1 1
IRS1 CD200R1 0 0 432 432 1 1
IRS1 TNFRSF11B 0 0 155 183 1 1
IRS1 NFKBIZ 0 0 0 150 1 1
IRS1 ASPH 0 0 202 221 1 1
IRS1 NOA1 0 0 0 188 1 1
IRS1 CDC42BPG 0 0 0 191 1 1
IRS1 PABPC1 270 0 484 633 1 1
IRS1 GH2 0 900 90 906 1 1
IRS1 SLC2A2 0 0 652 675 1 1
IRS1 LMNA 0 0 203 305 1 2
IRS1 SNAP23 0 0 187 192 1 1
IRS1 RAF1 0 0 391 457 1 2
IRS1 IRAK1 0 0 206 347 1 1
IRS1 TXK 0 0 0 161 1 1
IRS1 CSF3 0 0 155 154 1 1
IRS1 PTPRD 128 0 143 234 1 1
IRS1 RREB1 0 0 150 164 1 1
IRS1 HK2 0 0 283 305 1 2
IRS1 FGF7 0 500 66 522 1 1
IRS1 RBL1 0 0 127 218 1 1
IRS1 CYBA 0 0 151 156 1 1
IRS1 FGR 0 0 124 213 1 1
IRS1 PAX4 0 0 210 228 1 1
IRS1 CAMKK2 0 0 317 317 1 2
IRS1 CALM3 0 0 105 210 1 1
IRS1 PPARD 0 0 218 343 1 1
IRS1 ANKRD42 0 0 0 150 1 1
IRS1 ANKRD30BL 0 0 0 150 1 1
IRS1 JAK2 866 900 982 999 1 2
IRS1 GHRL 0 0 390 390 1 1
IRS1 PAK1 0 0 250 276 1 2
IRS1 SLC5A1 0 0 205 215 1 1
IRS1 SHC3 0 0 148 297 1 1
IRS1 ASB6 0 0 61 168 1 1
IRS1 MAFA 0 0 359 359 1 1
IRS1 PSME3 0 0 135 189 1 1
IRS1 CDH2 0 0 156 174 1 1
IRS1 AGO2 0 0 195 212 1 2
IRS1 LMNTD1 0 0 0 163 1 1
IRS1 PTN 0 0 181 205 1 1
IRS1 EIF2AK4 0 0 212 225 1 2
IRS1 RFC3 0 0 0 181 1 1
IRS1 SLC13A5 0 0 0 171 1 1
IRS1 CPT2 0 0 170 169 1 1
IRS1 HBEGF 0 0 218 235 1 1
IRS1 GDNF 0 900 171 913 1 2
IRS1 PPP1R12C 0 0 430 468 1 1
IRS1 STAT3 0 0 561 586 1 2
IRS1 EZH2 0 0 158 172 1 2
IRS1 ADAM9 0 0 150 169 1 1
IRS1 OR4S1 0 0 181 181 1 1
IRS1 SPTLC1 0 0 173 173 1 1
IRS1 ASB1 0 0 0 150 1 1
IRS1 XRCC6 0 0 96 158 1 1
IRS1 FREM2 0 0 0 179 1 1
IRS1 ERN1 0 0 507 557 1 2
IRS1 MYH6 0 0 202 202 1 1
IRS1 FREM3 0 0 0 179 1 1
IRS1 NF2 0 0 123 348 1 1
IRS1 IGF1R 974 900 989 999 1 2
IRS1 SDHC 0 0 206 206 1 1
IRS1 GRB14 213 0 504 650 1 1
IRS1 CSH2 0 0 486 486 1 1
IRS1 H1F0 0 0 61 218 1 1
IRS1 SRMS 0 0 0 162 1 1
IRS1 PI3 0 0 505 505 1 2
IRS1 ANKRD20A4 0 0 0 150 1 1
IRS1 PPARGC1A 0 0 653 669 1 2
IRS1 ANKRD28 0 0 0 150 1 1
IRS1 FGF10 0 500 0 516 1 1
IRS1 PCK1 0 0 468 515 1 1
IRS1 PDK1 0 0 234 262 1 2
IRS1 IL15 0 0 180 179 1 1
IRS1 PPRC1 0 0 90 287 1 1
IRS1 KLB 0 500 187 587 1 1
IRS1 MYC 0 0 504 507 1 2
IRS1 FCGR1B 0 0 390 390 1 1
IRS1 UBE2H 0 0 142 289 1 1
IRS1 DGAT1 0 0 423 427 1 2
IRS1 IL1R1 0 0 205 205 1 1
IRS1 CBLB 486 0 54 519 1 1
IRS1 WFS1 0 0 325 343 1 1
IRS1 NR0B2 0 0 234 234 1 1
IRS1 IFNA1 0 0 212 212 1 1
IRS1 ILK 0 0 254 303 1 1
IRS1 WNT5A 0 0 190 245 1 2
IRS1 IL18 0 0 286 291 1 2
IRS1 LAMA5 0 0 0 161 1 1
IRS1 PAX7 0 0 181 200 1 1
IRS1 BCDIN3D 0 0 125 179 1 1
IRS1 PIK3CA 873 900 987 999 1 2
IRS1 GAB2 0 500 483 604 1 1
IRS1 AMY1B 0 0 0 207 1 1
IRS1 ACACA 0 0 424 473 1 1
IRS1 ROR1 0 0 46 163 1 1
IRS1 CCDC8 0 0 154 160 1 1
IRS1 IL2RA 0 900 103 906 1 1
IRS1 TRAF2 0 0 150 221 1 2
IRS1 GPX7 0 0 0 215 1 1
IRS1 P4HB 0 0 165 171 1 2
IRS1 MEN1 0 0 96 173 1 1
IRS1 IBSP 0 0 46 150 1 1
IRS1 APPL1 0 0 402 402 1 1
IRS1 G6PC 0 0 681 700 1 1
IRS1 RICTOR 0 0 651 714 1 2
IRS1 HNRNPUL1 0 0 0 177 1 1
IRS1 DVL1 0 0 112 157 1 1
IRS1 GNAQ 0 0 248 248 1 1
IRS1 PIK3R3 747 800 965 999 1 1
IRS1 FANK1 0 0 0 150 1 1
IRS1 PPP1R3C 0 0 125 179 1 1
IRS1 C2CD4A 0 0 290 290 1 1
IRS1 ANKRD7 0 0 0 150 1 1
IRS1 ACTA1 0 0 96 186 1 1
IRS1 SYNPO 0 0 134 171 1 1
IRS1 SHANK1 0 0 46 167 1 1
IRS1 ACSL1 0 0 236 242 1 1
IRS1 PARK7 0 0 132 151 1 2
IRS1 EFNA5 0 0 158 176 1 1
IRS1 XRCC3 0 0 217 350 1 1
IRS1 NGDN 0 0 324 323 1 1
IRS1 DUSP4 0 0 103 229 1 1
IRS1 ANKRD16 0 0 0 150 1 1
IRS1 SLC2A3 0 0 424 463 1 1
IRS1 TTN 0 0 134 160 1 1
IRS1 ASB4 0 0 150 278 1 1
IRS1 MYCN 0 0 171 194 1 1
IRS1 LRP5 0 0 218 262 1 1
IRS1 SMAD4 0 0 245 251 1 2
IRS1 HDAC5 0 0 134 218 1 1
IRS1 FBXO24 0 0 60 266 1 1
IRS1 PBK 0 0 66 177 1 1
IRS1 HNRNPU 0 0 82 240 1 1
IRS1 PIP4K2A 0 0 63 179 1 1
IRS1 SCML2 0 0 0 181 1 1
IRS1 NPY 0 0 369 383 1 1
IRS1 AREG 0 0 193 193 1 1
IRS1 BRCA1 0 0 370 370 1 2
IRS1 CAND1 0 0 125 253 1 1
IRS1 STK11 0 0 518 547 1 2
IRS1 PFKM 0 0 171 171 1 1
IRS1 MAP2K1 0 0 469 505 1 1
IRS1 CDKN2D 0 0 0 150 1 1
IRS1 MAP3K8 0 0 155 154 1 1
IRS1 UBBP4 0 0 0 155 1 1
IRS1 BOLA2 0 0 0 175 1 1
IRS1 MAP2K5 0 0 113 158 1 1
IRS1 RB1CC1 0 0 206 215 1 2
IRS1 FBXW8 486 0 429 705 1 1
IRS1 PAPPA 0 0 181 223 1 1
IRS1 NFE2L2 0 0 293 296 1 2
IRS1 CIDEA 0 0 218 218 1 1
IRS1 LNPEP 0 0 261 261 1 1
IRS1 RNF214 0 0 51 265 1 1
IRS1 EML4 0 0 170 188 1 1
IRS1 CDK20 0 0 428 428 1 1
IRS1 AKT2 0 0 687 823 1 2
IRS1 ACAD9 0 0 0 190 1 1
IRS1 SND1 0 0 54 193 1 1
IRS1 PPP1R13B 0 0 0 154 1 1
IRS1 FRS2 0 500 391 682 1 1
IRS1 CTGF 0 0 260 304 1 1
IRS1 CSK 0 0 237 322 1 1
IRS1 RPS6KB2 0 800 387 921 1 2
IRS1 PPP2R5B 0 0 66 156 1 1
IRS1 COL4A1 0 0 108 235 1 1
IRS1 FKBP1A 0 0 403 440 1 2
IRS1 NR3C1 0 0 555 560 1 1
IRS1 IL2RG 0 900 116 907 1 1
IRS1 ABL2 0 0 66 184 1 1
IRS1 CISH 0 0 624 624 1 1
IRS1 CPT1B 0 0 261 284 1 1
IRS1 BLVRA 0 0 357 357 1 1
IRS1 GPX4 0 0 97 187 1 2
IRS1 TNS1 0 0 459 572 1 1
IRS1 SESN2 0 0 151 166 1 2
IRS1 HIST2H3PS2 0 0 218 218 1 1
IRS1 PXN 0 900 802 979 1 1
IRS1 SURF1 0 0 0 234 1 1
IRS1 ANKRD30A 0 0 0 150 1 1
IRS1 BRAF 0 0 112 213 1 2
IRS1 RAPGEF1 0 0 203 220 1 1
IRS1 GRAPL 0 0 0 217 1 1
IRS1 MUT 0 0 162 163 1 1
IRS1 AKAP13 0 0 90 157 1 1
IRS1 FGF18 0 500 0 507 1 1
IRS1 PCM1 0 0 0 523 1 1
IRS1 GAB4 0 0 0 252 1 1
IRS1 LYRM1 0 0 227 226 1 1
IRS1 MAP2K4 0 0 260 260 1 1
IRS1 PLD1 0 0 165 222 1 2
IRS1 PKDCC 0 0 0 163 1 1
IRS1 ADIPOQ 0 0 732 746 1 2
IRS1 SHANK2 0 0 0 180 1 1
IRS1 RAB6A 0 0 0 151 1 1
IRS1 PTK2 270 0 341 520 1 2
IRS1 ARG1 0 0 235 235 1 2
IRS1 NISCH 270 0 172 392 1 1
IRS1 GRB7 0 0 181 293 1 1
IRS1 MAPK8 681 800 758 986 1 2
IRS1 VIM 0 0 74 394 1 2
IRS1 FAM60A 0 0 0 231 1 1
IRS1 FRZB 0 0 95 210 1 1
IRS1 PRKAB1 0 0 216 216 1 2
IRS1 BCL11A 0 0 141 208 1 1
IRS1 SKP2 0 0 148 179 1 2
IRS1 AKR1B1 0 0 259 258 1 1
IRS1 HNF1A 0 0 243 242 1 1
IRS1 IGFBP1 0 0 517 520 1 1
IRS1 IL17A 0 0 200 200 1 2
IRS1 EGF 0 0 518 521 1 2
IRS1 SETD7 0 0 74 205 1 1
IRS1 PELI1 170 0 0 169 1 1
IRS1 GAK 0 0 0 242 1 1
IRS1 AGMO 0 0 195 195 1 1
IRS1 FASN 0 0 466 494 1 2
IRS1 PCSK1 0 0 204 222 1 1
IRS1 MLXIP 0 0 134 152 1 1
IRS1 SOS2 0 0 113 250 1 1
IRS1 CASP9 0 0 294 294 1 2
IRS1 ATG4A 0 0 0 250 1 2
IRS1 ITPR1 0 0 150 171 1 2
IRS1 TRAF6 0 0 234 264 1 2
IRS1 SESN3 0 0 170 184 1 1
IRS1 POMC 0 0 416 431 1 1
IRS1 COLGALT1 0 0 0 167 1 1
IRS1 CYCS 0 0 363 363 1 2
IRS1 DUSP12 0 0 123 171 1 1
IRS1 SLC27A5 0 0 213 213 1 1
IRS1 RPS6KA3 0 0 275 300 1 1
IRS1 PDP1 0 0 134 188 1 1
IRS1 MAPK9 213 800 395 919 1 2
IRS1 HSPB3 0 0 261 261 1 1
IRS1 XPO5 0 0 155 155 1 1
IRS1 RPTOR 675 900 652 989 1 2
IRS1 NES 0 0 142 180 1 2
IRS1 PDCD4 0 0 266 285 1 2
IRS1 CYP2E1 0 0 268 269 1 2
IRS1 CHAT 0 0 169 169 1 1
IRS1 CEBPD 0 0 244 243 1 1
IRS1 HSP90B1 0 0 151 164 1 1
IRS1 CCR2 0 0 250 250 1 2
IRS1 ANKRD66 0 0 0 150 1 1
IRS1 COL4A4 0 0 42 205 1 1
IRS1 SLC8A3 0 0 0 179 1 1
IRS1 TRIB1 0 0 145 203 1 1
IRS1 PPARA 0 0 633 649 1 2
IRS1 CETP 0 0 184 183 1 1
IRS1 ANKRD39 0 0 0 150 1 1
IRS1 ACHE 0 0 173 191 1 2
IRS1 LPL 0 0 558 577 1 1
IRS1 TEK 0 600 154 654 1 1
IRS1 ACVR1 0 0 74 168 1 1
IRS1 HSPA4 0 0 242 257 1 1
IRS1 CFD 0 0 243 242 1 1
IRS1 GHRHR 0 0 207 207 1 1
IRS1 GCGR 0 0 267 312 1 1
IRS1 PIK3R1 913 900 989 999 1 1
IRS1 DICER1 0 0 242 258 1 1
IRS1 RDX 0 0 113 174 1 1
IRS1 ASB10 0 0 0 150 1 1
IRS1 SCMH1 0 0 0 158 1 1
IRS1 ILF3 0 0 60 224 1 1
IRS1 ASB12 0 0 0 150 1 1
IRS1 ADRB3 0 0 406 406 1 1
IRS1 FLOT1 0 0 122 383 1 1
IRS1 ITLN1 0 0 242 241 1 1
IRS1 ITGB1 0 0 142 536 1 1
IRS1 DUSP9 0 0 382 416 1 1
IRS1 SNAPC3 0 0 0 200 1 1
IRS1 CASP7 0 0 174 189 1 1
IRS1 MME 0 0 140 186 1 1
IRS1 CUL1 270 0 194 386 1 1
IRS1 EIF4A1 0 0 202 207 1 1
IRS1 CREB3L3 0 0 254 254 1 1
IRS1 SNAI2 0 0 134 185 1 1
IRS1 LEPR 0 600 560 823 1 1
IRS1 ENPEP 0 0 325 325 1 1
IRS1 SFRP5 0 0 160 159 1 1
IRS1 ALB 0 0 519 570 1 2
IRS1 CD68 0 0 268 268 1 2
IRS1 CASP8 0 0 270 270 1 2
IRS1 ENHO 0 0 141 200 1 1
IRS1 SGK2 0 0 63 284 1 1
IRS1 KNG1 0 0 252 252 1 1
IRS1 PPP2R1B 0 0 69 189 1 1
IRS1 CCL2 0 0 520 520 1 2
IRS1 DOK1 0 0 306 306 1 1
IRS1 ABCB6 0 0 0 188 1 1
IRS1 SMAD3 131 0 272 362 1 2
IRS1 FAM155B 0 0 0 252 1 1
IRS1 ROCK1 213 0 294 571 1 2
IRS1 VAMP2 0 0 245 244 1 1
IRS1 SNCAIP 0 0 0 150 1 2
IRS1 DAG1 0 0 397 419 1 1
IRS1 HNF1B 0 0 195 195 1 1
IRS1 RAPH1 0 0 0 300 1 1
IRS1 BRWD1 0 0 0 151 1 1
IRS1 MYLK 0 0 134 165 1 1
IRS1 RNF123 270 0 0 300 1 1
IRS1 ANKRD54 0 0 0 150 1 1
IRS1 TNK2 0 0 181 268 1 1
IRS1 GPR98 0 0 0 205 1 1
IRS1 PKNOX1 0 0 142 204 1 1
IRS1 ADCY5 0 0 304 363 1 1
IRS1 ANKRD46 0 0 0 465 1 1
IRS1 EP300 0 0 218 218 1 2
IRS1 SIRPA 0 0 335 335 1 1
IRS1 CDK5 0 0 247 246 1 2
IRS1 ADIPOR1 0 0 518 518 1 1
IRS1 NUMB 170 0 0 169 1 1
IRS1 PDGFRB 0 600 324 732 1 2
IRS1 AP1M1 0 0 779 779 1 1
IRS1 SH3PXD2B 0 0 0 198 1 1
IRS1 CSNK2A2 270 0 91 316 1 1
IRS1 ANKRD55 0 0 289 370 1 1
IRS1 PKLR 0 0 161 213 1 1
IRS1 TPTE 0 0 0 242 1 1
IRS1 ADRA2A 0 0 145 150 1 1
IRS1 THADA 0 0 342 342 1 1
IRS1 GIPR 0 0 339 379 1 1
IRS1 IL4 0 900 391 939 1 1
IRS1 SCARB1 0 0 204 214 1 1
IRS1 PDGFRA 0 600 193 673 1 1
IRS1 FRK 0 0 125 268 1 1
IRS1 PLG 0 0 210 211 1 1
IRS1 RAB6C 0 0 0 151 1 1
IRS1 MLXIPL 0 0 466 477 1 1
IRS1 FNDC5 0 0 240 239 1 1
IRS1 SH3PXD2A 0 0 0 175 1 1
IRS1 IGF2BP1 0 0 113 304 1 1
IRS1 PRKCZ 213 800 664 949 1 1
IRS1 TMEM18 0 0 182 181 1 1
IRS1 BMP7 0 0 147 166 1 1
IRS1 FGF17 0 500 0 511 1 1
IRS1 RAP2B 0 0 184 208 1 1
IRS1 CDH1 213 0 468 563 1 2
IRS1 HSD17B11 0 0 123 219 1 1
IRS1 ACTC1 0 0 46 169 1 1
IRS1 MAP3K9 0 0 46 168 1 1
IRS1 AGER 0 0 261 261 1 2
IRS1 HYOU1 0 0 219 246 1 1
IRS1 YWHAG 431 0 57 691 1 1
IRS1 CERS2 0 0 154 153 1 1
IRS1 GLI2 0 0 134 182 1 2
IRS1 CDK6 0 0 218 239 1 2
IRS1 SIRT6 0 0 296 322 1 2
IRS1 HMGCS2 0 0 162 202 1 1
IRS1 NEUROG3 0 0 140 159 1 1
IRS1 ACVR2B 0 0 163 248 1 1
IRS1 ATP2A1 213 0 447 546 1 1
IRS1 RHOB 0 0 116 152 1 1
IRS1 INVS 0 0 0 150 1 1
IRS1 IL1A 0 0 241 240 1 1
IRS1 CEACAM1 0 0 183 183 1 1
IRS1 PAX6 0 0 108 214 1 1
IRS1 BDKRB2 0 0 123 155 1 1
IRS1 WNT1 0 0 181 237 1 2
IRS1 POLG 0 0 0 188 1 1
IRS1 SYTL4 0 0 108 201 1 1
IRS1 ABCA1 0 0 323 348 1 2
IRS1 ALK 462 0 671 837 1 2
IRS1 ROCK2 0 0 164 654 1 1
IRS1 CUL5 0 0 155 161 1 1
IRS1 IAPP 0 0 363 392 1 2
IRS1 ABCC8 0 0 341 367 1 1
IRS1 DPP4 0 0 391 429 1 1
IRS1 NR3C2 0 0 231 247 1 1
IRS1 EREG 0 0 157 156 1 1
IRS1 BCHE 0 0 123 157 1 1
IRS1 AANAT 0 0 351 351 1 1
IRS1 PIK3R5 0 800 422 879 1 1
IRS1 FKBP5 0 0 144 162 1 1
IRS1 MAP3K11 0 0 141 228 1 1
IRS1 MAF 0 0 158 157 1 1
IRS1 BOLA2B 0 0 0 175 1 1
IRS1 PPP2R5A 0 0 97 240 1 1
IRS1 CSH1 0 650 202 708 1 1
IRS1 PDK2 0 0 283 325 1 1
IRS1 GABARAPL1 0 0 181 213 1 2
IRS1 RFTN1 0 0 60 273 1 1
IRS1 ICAM1 0 0 298 341 1 2
IRS1 ZEB1 0 0 210 210 1 2
IRS1 SOX9 0 0 165 205 1 1
IRS1 FOXA3 0 0 103 185 1 1
IRS1 SIRT7 0 0 284 310 1 2
IRS1 BCR 213 0 70 236 1 2
IRS1 ESR2 0 0 336 336 1 1
IRS1 WISP2 0 0 138 174 1 1
IRS1 PTPRC 213 0 167 328 1 1
IRS1 R3HDM1 0 0 81 173 1 1
IRS1 COBLL1 0 0 341 434 1 1
IRS1 USP6 0 0 166 165 1 1
IRS1 IGFBP2 0 0 413 434 1 1
IRS1 ITGAV 0 900 428 941 1 1
IRS1 RHOQ 0 0 204 231 1 1
IRS1 MTTP 0 0 391 401 1 1
IRS1 BEST4 0 0 0 167 1 1
IRS1 CXCL12 0 0 162 180 1 2
IRS1 BAX 0 0 195 195 1 2
IRS1 PYY 0 0 207 207 1 1
IRS1 TIMP1 0 0 181 181 1 1
IRS1 FGF4 0 500 0 522 1 1
IRS1 SLC38A2 0 0 151 150 1 1
IRS1 CARTPT 0 0 166 165 1 1
IRS1 FABP5 0 0 162 196 1 1
IRS1 STX4 0 0 235 253 1 1
IRS1 PLA2G1B 0 0 180 238 1 1
IRS1 SYN1 0 0 142 161 1 1
IRS1 EIF4G1 0 0 334 342 1 2
IRS1 RHOA 0 0 342 372 1 2
IRS1 PARP1 0 0 156 156 1 2
IRS1 AR 0 0 767 773 1 2
IRS1 GSR 0 0 203 203 1 1
IRS1 INSR 879 900 982 999 1 1
IRS1 HSPA8 0 0 175 312 1 2
IRS1 GNRH1 0 0 150 184 1 1
IRS1 CRTC2 0 0 392 405 1 1
IRS1 NR1D2 0 0 0 202 1 1
IRS1 CDKN1A 0 0 285 286 1 2
IRS1 SPP1 0 0 241 240 1 2
IRS1 SQSTM1 0 0 703 770 1 2
IRS1 BNIP3 0 0 210 211 1 2
IRS1 PCK2 0 0 556 585 1 1
IRS1 GLI3 0 0 133 178 1 1
IRS1 ABCG1 0 0 193 208 1 2
IRS1 SIRT3 0 0 334 350 1 2
IRS1 KEAP1 0 0 244 260 1 2
IRS1 B2M 0 0 155 154 1 1
IRS1 MMP9 0 0 323 339 1 2
IRS1 KLF15 0 0 218 255 1 1
IRS1 MAPK3 270 900 659 975 1 2
IRS1 ROS1 0 0 112 214 1 1
IRS1 AMY1C 0 0 0 207 1 1
IRS1 FGF1 0 500 150 556 1 1
IRS1 UHRF1BP1 0 0 203 203 1 1
IRS1 DNMT1 0 0 184 183 1 2
IRS1 GLP1R 0 0 375 418 1 1
IRS1 CAV2 0 0 309 327 1 1
IRS1 GRAP2 0 0 872 895 1 1
IRS1 TUBGCP3 0 0 0 171 1 1
IRS1 FOXG1 0 0 45 554 1 1
IRS1 CIT 0 0 0 191 1 1
IRS1 MSN 0 0 100 161 1 1
IRS1 SERPINA12 0 0 256 256 1 1
IRS1 INS 0 900 977 997 1 2
IRS1 ATG13 0 0 241 268 1 2
IRS1 GAS6 0 0 134 195 1 1
IRS1 ACTB 0 0 607 649 1 2
IRS1 COX4I1 0 0 235 235 1 1
IRS1 CRP 0 0 504 548 1 2
IRS1 UGCG 0 0 195 195 1 1
IRS1 PSEN1 0 0 334 335 1 2
IRS1 ATF2 0 0 150 223 1 1
IRS1 WRN 0 0 74 326 1 1
IRS1 CEBPA 0 0 470 495 1 1
IRS1 DES 0 0 0 258 1 2
IRS1 SOX2 0 0 211 211 1 2
IRS1 NEUROD1 0 0 248 248 1 1
IRS1 ABHD12B 0 0 0 179 1 1
IRS1 FBXW7 0 0 192 217 1 2
IRS1 ANKRD2 0 0 61 186 1 1
IRS1 ANKHD1-EIF4EBP3 0 0 0 166 1 1
IRS1 HDAC4 0 0 156 170 1 2
IRS1 ALDOB 0 0 67 210 1 1
IRS1 HPGDS 0 0 459 459 1 1
IRS1 LBP 0 0 113 174 1 1
IRS1 SBF1 0 0 0 187 1 1
IRS1 HSP90AA1 0 0 479 544 1 2
IRS1 PNPLA2 0 0 469 497 1 2
IRS1 IL3 0 0 235 235 1 1
IRS1 TFEB 0 0 233 237 1 2
IRS1 BCL3 0 0 42 151 1 1
IRS1 ASB13 0 0 0 150 1 1
IRS1 JUN 0 0 681 700 1 2
IRS1 ITPR3 0 0 150 179 1 1
IRS1 PLCG1 0 0 214 347 1 1
IRS1 TYK2 213 0 321 499 1 1
IRS1 FABP3 0 0 215 224 1 1
IRS1 BCL2L11 0 0 325 325 1 2
IRS1 FSCN1 0 0 150 211 1 1
IRS1 CDH17 0 0 456 456 1 1
IRS1 TSC1 0 0 468 696 1 2
IRS1 SLC8A2 0 0 0 179 1 1
IRS1 POLDIP3 0 0 241 352 1 1
IRS1 DOK4 0 0 450 240 1 1
IRS1 NRF1 0 0 212 212 1 2
IRS1 KL 0 800 260 874 1 2
IRS1 SI 0 0 341 341 1 1
IRS1 SERPINA1 0 0 134 151 1 2
IRS1 DOK5 0 0 519 519 1 1
IRS1 CYP19A1 0 0 324 338 1 2
IRS1 CAV1 213 900 821 985 1 2
IRS1 ERBB4 0 600 234 697 1 1
IRS1 KIF1B 0 0 0 190 1 1
IRS1 PROP1 0 0 181 182 1 1
IRS1 HSPA1A 0 0 184 289 1 1
IRS1 SRF 0 0 163 163 1 1
IRS1 SIK2 213 0 378 503 1 1
IRS1 ULK2 0 0 150 199 1 2
IRS1 FFAR2 0 0 167 167 1 1
IRS1 SLC8A1 0 0 72 205 1 1
IRS1 MAP2K3 0 0 175 175 1 1
IRS1 GPR83 0 800 0 800 1 1
IRS1 ENSG00000268434 0 0 0 165 1 1
IRS1 YBX2 0 0 0 152 1 1
IRS1 JAK3 270 900 467 962 1 1
IRS1 PIK3CG 0 800 562 949 1 1
IRS1 CYP7A1 0 0 211 212 1 1
IRS1 DNTT 0 0 151 150 1 1
IRS1 SNCA 0 0 235 235 1 2
IRS1 CRTC3 0 0 0 156 1 1
IRS1 CASP1 0 0 284 296 1 2
IRS1 NOS1 0 0 232 231 1 1
IRS1 SCO1 0 0 270 270 1 1
IRS1 AKT1S1 0 0 603 613 1 1
IRS1 EXOSC4 0 0 193 193 1 1
IRS1 CCNA2 0 0 218 218 1 1
IRS1 COL3A1 0 0 74 153 1 1
IRS1 NOS1AP 0 0 134 167 1 1
IRS1 CRK 213 900 761 982 1 1
IRS1 RIPK2 0 0 81 175 1 2
IRS1 LIMK2 0 0 0 159 1 1
IRS1 TFAM 0 0 324 347 1 2
IRS1 NFATC3 0 0 143 185 1 1
IRS1 SLC27A6 0 0 386 386 1 1
IRS1 MMP2 0 0 282 297 1 2
IRS1 IGF2BP3 0 0 124 218 1 1
IRS1 RBP4 0 0 496 522 1 1
IRS1 AWAT1 0 0 142 161 1 1
IRS1 ENSG00000270024 0 0 209 395 1 1
IRS1 NCOA3 0 0 212 212 1 1
IRS1 FER 213 0 81 323 1 1
IRS1 MFN1 0 0 159 158 1 2
IRS1 IGFBP3 0 0 519 542 1 2
IRS1 CAMK1D 0 0 270 283 1 1
IRS1 EIF2AK2 0 800 169 942 1 2
IRS1 CD8A 0 0 249 248 1 1
IRS1 RING1 0 0 134 157 1 1
IRS1 IRS2 270 900 950 944 1 1
IRS1 CALR 0 0 305 305 1 1
IRS1 ESPNL 0 0 0 150 1 1
IRS1 DNAJC3 0 0 155 154 1 1
IRS1 IL7R 0 600 61 608 1 1
IRS1 ANKHD1 0 0 0 166 1 1
IRS1 SP6 0 0 379 407 1 1
IRS1 MIB2 0 0 0 405 1 1
IRS1 ELOVL6 0 0 228 227 1 1
IRS1 SOD1 0 0 182 264 1 2
IRS1 LTA 0 0 67 211 1 1
IRS1 GTPBP4 0 0 184 183 1 1
IRS1 RPN2 0 0 0 181 1 1
IRS1 TBC1D4 0 0 736 746 1 1
IRS1 TBL1X 0 0 146 164 1 1
IRS1 ERN2 0 0 97 189 1 1
IRS1 NCK2 270 900 503 960 1 1
IRS1 USH1G 0 0 0 150 1 1
IRS1 ANKRD36C 0 0 0 150 1 1
IRS1 SULF1 0 0 0 207 1 1
IRS1 ANKRD44 0 0 0 150 1 1
IRS1 FGF6 0 500 0 522 1 1
IRS1 SHH 0 0 220 238 1 2
IRS1 CSNK1A1 270 0 87 305 1 1
IRS1 GRB2 870 900 989 999 1 1
IRS1 ANK1 0 0 689 709 1 1
IRS1 AZGP1 0 0 201 201 1 1
IRS1 NFKBIE 0 0 46 155 1 1
IRS1 IGFBP4 0 0 342 366 1 1
IRS1 ANKRD36B 0 0 0 150 1 1
IRS1 ABI1 0 0 389 389 1 1
IRS1 FYN 462 0 820 915 1 1
IRS1 YWHAE 745 0 539 947 1 1
IRS1 PIP5K1A 0 0 0 205 1 1
IRS1 GHRH 0 0 245 265 1 1
IRS1 INSIG2 0 0 317 317 1 1
IRS1 ASB16 0 0 0 150 1 1
IRS1 LCK 0 900 421 945 1 1
IRS1 WDFY2 0 0 151 169 1 1
IRS1 ACAP1 0 0 66 321 1 1
IRS1 FST 0 0 195 235 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0042169 Molecular Function SH2 domain binding enables ISS
GO:0005158 Molecular Function insulin receptor binding enables IBA
GO:0005158 Molecular Function insulin receptor binding enables IPI
GO:0005159 Molecular Function insulin-like growth factor receptor binding enables IPI
GO:0043548 Molecular Function phosphatidylinositol 3-kinase binding enables IBA
GO:0043548 Molecular Function phosphatidylinositol 3-kinase binding enables IPI
GO:0043548 Molecular Function phosphatidylinositol 3-kinase binding enables ISS
GO:0001784 Molecular Function phosphotyrosine residue binding enables IPI
GO:0005515 Molecular Function protein binding enables IPI
GO:0005080 Molecular Function protein kinase C binding enables ISS
GO:0030159 Molecular Function signaling receptor complex adaptor activity enables IDA
GO:0005068 Molecular Function transmembrane receptor protein tyrosine kinase adaptor activity enables ISS
GO:0071398 Biological Process cellular response to fatty acid involved_in ISS
GO:0032869 Biological Process cellular response to insulin stimulus involved_in IMP
GO:0019221 Biological Process cytokine-mediated signaling pathway involved_in IGI
GO:0042593 Biological Process glucose homeostasis involved_in TAS
GO:0008286 Biological Process insulin receptor signaling pathway involved_in IBA
GO:0008286 Biological Process insulin receptor signaling pathway involved_in IDA
GO:0008286 Biological Process insulin receptor signaling pathway involved_in IMP
GO:0008286 Biological Process insulin receptor signaling pathway involved_in IPI
GO:0048009 Biological Process insulin-like growth factor receptor signaling pathway involved_in IPI
GO:0046627 Biological Process negative regulation of insulin receptor signaling pathway involved_in ISS
GO:0046676 Biological Process negative regulation of insulin secretion involved_in IDA
GO:0043491 Biological Process phosphatidylinositol 3-kinase/protein kinase B signal transduction involved_in IDA
GO:0008284 Biological Process positive regulation of cell population proliferation involved_in NAS
GO:0032000 Biological Process positive regulation of fatty acid beta-oxidation involved_in IMP
GO:0046326 Biological Process positive regulation of glucose import involved_in IDA
GO:0046326 Biological Process positive regulation of glucose import involved_in IMP
GO:0010907 Biological Process positive regulation of glucose metabolic process involved_in IMP
GO:0045725 Biological Process positive regulation of glycogen biosynthetic process involved_in IMP
GO:0045725 Biological Process positive regulation of glycogen biosynthetic process involved_in NAS
GO:0046628 Biological Process positive regulation of insulin receptor signaling pathway involved_in IDA
GO:0046628 Biological Process positive regulation of insulin receptor signaling pathway involved_in ISS
GO:0051897 Biological Process positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction involved_in ISS
GO:0032868 Biological Process response to insulin involved_in IDA
GO:0007165 Biological Process signal transduction involved_in TAS
GO:0005901 Cellular Component caveola located_in IDA
GO:0005737 Cellular Component cytoplasm located_in ISS
GO:0005829 Cellular Component cytosol is_active_in IBA
GO:0005829 Cellular Component cytosol located_in IDA
GO:0005829 Cellular Component cytosol located_in TAS
GO:0005899 Cellular Component insulin receptor complex part_of ISS
GO:0043231 Cellular Component intracellular membrane-bounded organelle located_in ISS
GO:0005654 Cellular Component nucleoplasm located_in IDA
GO:0005634 Cellular Component nucleus located_in ISS
GO:0005886 Cellular Component plasma membrane is_active_in IBA
GO:0005886 Cellular Component plasma membrane located_in IDA
GO:0005886 Cellular Component plasma membrane located_in TAS
Pathways
Name DB ID
PI3K Cascade Reactome R-HSA-109704
IRS-mediated signalling Reactome R-HSA-112399
SOS-mediated signalling Reactome R-HSA-112412
PIP3 activates AKT signaling Reactome R-HSA-1257604
Interleukin-7 signaling Reactome R-HSA-1266695
Cytokine Signaling in Immune system Reactome R-HSA-1280215
Signal Transduction Reactome R-HSA-162582
Disease Reactome R-HSA-1643685
Signaling by NTRKs Reactome R-HSA-166520
Immune System Reactome R-HSA-168256
Signaling by NTRK1 (TRKA) Reactome R-HSA-187037
PI3K/AKT activation Reactome R-HSA-198203
Negative regulation of the PI3K/AKT network Reactome R-HSA-199418
Signaling by ALK Reactome R-HSA-201556
PI3K/AKT Signaling in Cancer Reactome R-HSA-2219528
Constitutive Signaling by Aberrant PI3K in Cancer Reactome R-HSA-2219530
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) Reactome R-HSA-2404192
IGF1R signaling cascade Reactome R-HSA-2428924
IRS-related events triggered by IGF1R Reactome R-HSA-2428928
Signaling by Leptin Reactome R-HSA-2586552
Signaling by Interleukins Reactome R-HSA-449147
Diseases of signal transduction by growth factor receptors and second messengers Reactome R-HSA-5663202
RAF/MAP kinase cascade Reactome R-HSA-5673001
MAPK family signaling cascades Reactome R-HSA-5683057
MAPK1/MAPK3 signaling Reactome R-HSA-5684996
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling Reactome R-HSA-6811558
IRS activation Reactome R-HSA-74713
Signal attenuation Reactome R-HSA-74749
Insulin receptor signalling cascade Reactome R-HSA-74751
Signaling by Insulin receptor Reactome R-HSA-74752
Intracellular signaling by second messengers Reactome R-HSA-9006925
Signaling by Receptor Tyrosine Kinases Reactome R-HSA-9006934
Signaling by NTRK3 (TRKC) Reactome R-HSA-9034015
Activated NTRK3 signals through PI3K Reactome R-HSA-9603381
Signaling by ALK in cancer Reactome R-HSA-9700206
Signaling by ALK fusions and activated point mutants Reactome R-HSA-9725370
Growth hormone receptor signaling Reactome R-HSA-982772
Neuroinflammation and glutamatergic signaling (WP5083) WikiPathways WP5083_r120385
Alzheimer's disease (WP5124) WikiPathways WP5124_r123917
Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling (WP3850) WikiPathways WP3850_r121711
Oncostatin M signaling pathway (WP2374) WikiPathways WP2374_r120781
Congenital generalized lipodystrophy (WP5101) WikiPathways WP5101_r123625
Glioblastoma signaling pathways (WP2261) WikiPathways WP2261_r123065
Alzheimer's disease and miRNA effects (WP2059) WikiPathways WP2059_r119468
Alpha 6 beta 4 signaling pathway (WP244) WikiPathways WP244_r120686
Leptin-insulin signaling overlap (WP3935) WikiPathways WP3935_r118425
Adipogenesis (WP236) WikiPathways WP236_r105873
IL-4 signaling pathway (WP395) WikiPathways WP395_r120704
Transcription factor regulation in adipogenesis (WP3599) WikiPathways WP3599_r105845
Focal adhesion: PI3K-Akt-mTOR-signaling pathway (WP3932) WikiPathways WP3932_r124527
Roles of ceramides in the development of insulin resistance (WP5181) WikiPathways WP5181_r124468
Brain-derived neurotrophic factor (BDNF) signaling pathway (WP2380) WikiPathways WP2380_r120727
Type II diabetes mellitus (WP1584) WikiPathways WP1584_r122869
DNA damage response (only ATM dependent) (WP710) WikiPathways WP710_r116542
Insulin signaling (WP481) WikiPathways WP481_r120562
Leptin signaling pathway (WP2034) WikiPathways WP2034_r120670
FOXA2 pathway (WP5066) WikiPathways WP5066_r116631
Prolactin signaling pathway (WP2037) WikiPathways WP2037_r122570
Gastrin signaling pathway (WP4659) WikiPathways WP4659_r116555
EPO receptor signaling (WP581) WikiPathways WP581_r117099
Nonalcoholic fatty liver disease (WP4396) WikiPathways WP4396_r123350
Insulin signaling in adipocytes (diabetic condition) (WP3635) WikiPathways WP3635_r116600
AGE/RAGE pathway (WP2324) WikiPathways WP2324_r120674
Interferon type I signaling pathways (WP585) WikiPathways WP585_r107188
PI3K-Akt signaling pathway (WP4172) WikiPathways WP4172_r122580
Angiopoietin-like protein 8 regulatory pathway (WP3915) WikiPathways WP3915_r123920
Insulin signaling in adipocytes (normal condition) (WP3634) WikiPathways WP3634_r116602
Transcripts
Accession Version MolecularType Name NCBI Comments
NM_005544 3 mRNA None NC_000002 Reference
XM_047444224 1 mRNA transcript variant X2 NC_000002 Reference
XM_047444223 1 mRNA transcript variant X1 NC_000002 Reference