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LIF

LIF interleukin 6 family cytokine
General Information
Name LIF interleukin 6 family cytokine
Alias
  • leukemia inhibitory factor
  • D factor
  • cholinergic differentiation factor
  • differentiation inhibitory activity
  • differentiation-inducing factor
  • differentiation-stimulating factor
  • hepatocyte-stimulating factor III
  • human interleukin in DA cells
  • melanoma-derived LPL inhibitor
Gene_family Receptor ligands|Interleukin 6 type cytokine family
organism Homo sapiens
entrez_id 3976
location 22q12.2
transcript_count 3
exon_count 3
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez The protein encoded by this gene is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]
    Stringdb Leukemia inhibitory factor; LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes; Endogenous ligands
    nextProt LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
LIF BioGRID KRTAP12-3 GeneID BioGRID Two-hybrid
LIF BioGRID NCALD GeneID BioGRID Two-hybrid
LIF BioGRID HPGDS GeneID BioGRID Two-hybrid
LIF BioGRID KRT31 GeneID BioGRID Two-hybrid
LIF Protein IL6ST GeneID HPRD
LIF Protein LIFR GeneID HPRD
LIF BioGRID LIFR GeneID BioGRID Reconstituted Complex
StringDB
A B experiments database textmining combined score hadb nhadb
LIF ID1 0 0 217 245 1 1
LIF LEFTY1 0 0 322 321 1 1
LIF CXCL8 0 900 517 956 1 2
LIF ACVR1C 0 0 108 163 1 1
LIF WNT7A 0 0 306 311 1 1
LIF IL6R 0 600 404 764 1 1
LIF GBX2 0 0 340 340 1 1
LIF PAX2 0 0 284 284 1 1
LIF ISL1 0 0 323 341 1 1
LIF HPS5 0 0 42 563 1 1
LIF WNT7B 0 0 182 181 1 1
LIF CYP27B1 0 0 0 152 1 1
LIF HIF1A 0 0 323 339 1 2
LIF EDN1 0 0 290 347 1 1
LIF POSTN 0 0 166 187 1 1
LIF NKX6-2 0 0 211 211 1 1
LIF BMP15 0 0 172 171 1 1
LIF IL1B 0 900 594 958 1 2
LIF CXCR2 0 0 183 183 1 1
LIF RHO 0 0 167 167 1 2
LIF PLA2G4A 0 0 99 361 1 1
LIF WNT2B 0 0 150 235 1 1
LIF HOXA11 0 0 270 300 1 1
LIF TNFRSF1B 0 0 140 159 1 1
LIF ERAP1 0 0 66 231 1 1
LIF MYF5 0 0 218 218 1 1
LIF FCGR3A 0 0 156 155 1 1
LIF HRAS 0 0 181 251 1 2
LIF CTNNB1 0 0 459 466 1 2
LIF SOCS7 0 0 284 284 1 1
LIF CDK2 0 0 211 230 1 2
LIF EPHA2 0 0 57 188 1 1
LIF EGR1 0 0 235 235 1 2
LIF KLF7 0 0 360 360 1 1
LIF MTOR 0 0 270 270 1 2
LIF MYO5A 0 0 0 459 1 1
LIF POTEF 0 0 261 291 1 1
LIF SORT1 417 0 96 460 1 1
LIF SAA1 0 900 67 905 1 1
LIF JARID2 0 0 212 212 1 1
LIF HIST1H4F 0 0 181 181 1 1
LIF CXCR4 0 0 402 412 1 2
LIF CYR61 0 0 112 196 1 1
LIF FGF13 0 0 519 585 1 1
LIF HLA-G 0 0 262 262 1 1
LIF KLF17 0 0 151 150 1 1
LIF NOTCH1 0 0 454 461 1 2
LIF MMP1 0 900 208 925 1 1
LIF CBY1 0 0 90 181 1 1
LIF PTGS1 0 0 134 166 1 1
LIF CD40LG 0 0 163 163 1 1
LIF SOCS5 0 0 240 239 1 1
LIF STAT1 0 0 503 523 1 2
LIF NDP 0 0 181 181 1 1
LIF MYOG 0 0 234 234 1 1
LIF TNFRSF1A 0 0 240 262 1 1
LIF OCLN 0 0 142 160 1 1
LIF IL3RA 0 600 54 605 1 1
LIF ACAN 0 0 210 210 1 1
LIF MOG 0 0 181 181 1 1
LIF LPAR3 0 0 194 610 1 1
LIF IL6 0 900 755 978 1 2
LIF IL2RB 0 600 90 620 1 1
LIF APC 0 0 123 155 1 1
LIF IFNG 0 0 457 479 1 2
LIF HIST2H2AC 0 0 187 187 1 1
LIF CCL5 0 900 457 943 1 2
LIF TGFB3 0 0 324 323 1 1
LIF FGF14 0 0 55 413 1 1
LIF CREB1 0 0 244 243 1 2
LIF CCL13 0 0 152 151 1 1
LIF GDF9 0 0 309 319 1 1
LIF POU3F2 0 0 233 232 1 1
LIF IGFBP5 0 0 172 171 1 1
LIF DGCR8 0 0 180 191 1 1
LIF CREBBP 0 0 123 155 1 1
LIF IL4R 0 600 113 643 1 1
LIF ZFX 0 0 233 232 1 1
LIF WNT11 0 0 261 261 1 1
LIF EPO 0 0 459 459 1 2
LIF CLCF1 0 0 468 550 1 1
LIF WNT8A 0 0 218 218 1 1
LIF ANXA5 0 0 294 311 1 2
LIF FGF21 0 0 217 492 1 2
LIF OSMR 0 600 556 828 1 1
LIF TAGLN 0 0 183 183 1 1
LIF DNMT3A 0 0 327 331 1 2
LIF UHRF1 0 0 212 212 1 1
LIF DNMT3B 0 0 386 400 1 1
LIF BCL2L1 0 0 296 316 1 2
LIF RELA 0 0 150 171 1 2
LIF CCL4L1 0 0 390 394 1 1
LIF ELF5 0 0 173 173 1 1
LIF SOX3 0 0 194 403 1 1
LIF KITLG 0 0 686 715 1 1
LIF PIWIL2 0 0 184 205 1 1
LIF LECT1 0 0 0 183 1 1
LIF ADCYAP1 0 0 173 173 1 1
LIF STAT4 0 0 138 433 1 1
LIF ZIC1 0 0 113 150 1 1
LIF KISS1 0 0 147 168 1 1
LIF NEFM 0 0 146 164 1 1
LIF ATRX 0 0 146 169 1 1
LIF UTF1 0 0 421 433 1 1
LIF TNFSF15 0 0 87 187 1 1
LIF SLC18A3 0 0 240 239 1 1
LIF HIST4H4 0 0 181 181 1 1
LIF PROK1 0 0 170 189 1 1
LIF MAP2K7 0 0 358 358 1 1
LIF CX3CL1 0 0 211 211 1 1
LIF NOS2 0 0 142 157 1 2
LIF TLR4 0 0 274 289 1 2
LIF SMAD2 0 0 325 325 1 2
LIF FGFR2 0 0 208 208 1 1
LIF IL9R 0 600 0 600 1 1
LIF OLIG1 0 0 306 306 1 1
LIF DUSP5 0 0 90 172 1 1
LIF GAPDH 0 0 556 562 1 2
LIF HOXA9 0 0 123 160 1 1
LIF SDHC 0 0 218 218 1 1
LIF IGF1R 0 0 202 202 1 2
LIF FGF10 0 0 233 433 1 1
LIF PPARGC1A 0 0 157 156 1 2
LIF H1F0 0 0 142 160 1 1
LIF FABP7 0 0 194 194 1 1
LIF IL1R1 0 0 317 354 1 1
LIF MYC 0 0 561 620 1 2
LIF SLC1A3 0 0 260 260 1 1
LIF IL15 0 0 469 478 1 1
LIF S100A7 0 0 296 296 1 1
LIF KISS1R 0 0 108 198 1 1
LIF PAX7 0 0 264 276 1 1
LIF WNT5A 0 0 323 349 1 2
LIF IL18 0 900 380 935 1 2
LIF IFNA1 0 0 292 292 1 1
LIF IL27RA 0 600 282 700 1 1
LIF CLEC11A 0 0 334 334 1 1
LIF IL2RA 0 600 150 645 1 1
LIF ACP5 0 0 155 154 1 1
LIF UBTFL1 0 0 155 154 1 1
LIF IBSP 0 0 181 181 1 1
LIF NOG 0 0 413 412 1 1
LIF MAP2 0 0 288 288 1 2
LIF ZFP57 0 0 164 163 1 1
LIF TBX5 0 0 292 297 1 1
LIF EVX1 0 0 142 157 1 1
LIF IL12A 0 900 0 902 1 1
LIF TCL1B 0 0 334 334 1 1
LIF STC1 0 0 134 165 1 1
LIF DPPA5 0 0 294 306 1 1
LIF ACTA1 0 0 147 221 1 1
LIF SYNPO 0 0 64 164 1 1
LIF SMAD4 0 0 243 242 1 2
LIF LRP5 0 0 171 218 1 1
LIF MYCN 0 0 280 280 1 1
LIF HIST1H4L 0 0 181 181 1 1
LIF TNFRSF12A 0 0 74 234 1 1
LIF ACRC 0 0 181 181 1 1
LIF DLX2 0 0 160 159 1 1
LIF ZSCAN10 0 0 119 152 1 1
LIF INHBA 0 0 144 213 1 1
LIF CD80 0 0 193 193 1 2
LIF PDGFB 0 0 218 237 1 2
LIF NPY 0 0 272 272 1 1
LIF AREG 0 0 285 365 1 1
LIF SLC12A4 0 0 0 211 1 1
LIF BTC 0 0 160 176 1 1
LIF TCF3 0 0 150 196 1 1
LIF UNK 0 0 183 194 1 1
LIF OSM 0 600 833 931 1 1
LIF FZD2 0 0 134 192 1 1
LIF FUT4 0 0 594 601 1 1
LIF MAP2K1 0 0 295 295 1 1
LIF NFE2L2 0 0 63 165 1 2
LIF PAPPA 0 0 161 252 1 1
LIF EHMT2 0 0 282 282 1 2
LIF NKX6-1 0 0 172 171 1 1
LIF TDGF1 0 0 310 309 1 1
LIF MECP2 0 0 212 212 1 1
LIF MAP2K5 0 0 181 187 1 1
LIF MARCH7 0 0 218 218 1 1
LIF MNX1 0 0 124 156 1 1
LIF HOXB4 0 0 194 214 1 1
LIF LHX1 0 0 181 182 1 1
LIF TSLP 0 0 138 169 1 1
LIF CDK4 0 0 157 156 1 2
LIF EGFR 0 600 327 735 1 2
LIF HIST1H4I 0 0 181 181 1 1
LIF MYD88 0 0 171 171 1 2
LIF DCN 0 0 138 156 1 2
LIF TP53 0 0 414 424 1 2
LIF LCN2 0 900 150 913 1 1
LIF MDM2 0 0 181 184 1 2
LIF ALOX15 0 0 63 166 1 1
LIF IL20RA 0 600 0 600 1 1
LIF HDAC2 0 0 180 179 1 1
LIF NUP210L 0 0 0 190 1 1
LIF DAZL 0 0 395 417 1 1
LIF WNT4 0 0 327 328 1 1
LIF PAEP 0 0 401 400 1 1
LIF LINGO1 0 0 212 213 1 1
LIF TNFRSF11B 0 0 233 254 1 1
LIF GIG25 0 0 156 157 1 1
LIF CSF3 0 900 658 965 1 1
LIF LMNA 0 0 143 246 1 2
LIF PITX2 0 0 146 199 1 1
LIF GNL3 0 0 150 172 1 1
LIF FGF7 0 0 322 507 1 1
LIF HAND1 0 0 108 163 1 1
LIF OCM 0 0 283 295 1 1
LIF IL20RB 0 600 0 600 1 1
LIF PPARD 0 0 97 330 1 1
LIF WNT5B 0 0 163 181 1 1
LIF EMX2 0 0 217 217 1 1
LIF SEMA3C 0 0 160 190 1 1
LIF JAK2 0 600 517 801 1 2
LIF APAF1 0 0 112 187 1 2
LIF CDH2 0 0 294 294 1 1
LIF PTX3 0 0 114 162 1 1
LIF PTN 0 0 123 160 1 1
LIF TGFA 0 0 181 204 1 1
LIF SEMA3B 0 0 134 152 1 1
LIF POU5F1B 0 0 0 216 1 1
LIF RLIM 0 0 180 180 1 1
LIF EZH2 0 0 305 305 1 2
LIF STAT3 0 900 795 978 1 2
LIF GDNF 0 0 605 623 1 2
LIF HBEGF 0 900 424 944 1 1
LIF DKK2 0 0 118 158 1 1
LIF PHLDA2 0 0 85 249 1 1
LIF IFNA2 0 0 170 169 1 1
LIF ITGA5 0 0 155 206 1 1
LIF EDN2 0 0 253 472 1 1
LIF GATA3 0 0 218 231 1 1
LIF NF2 0 0 387 386 1 1
LIF NR2F1 0 0 183 183 1 1
LIF SOX4 0 0 160 159 1 1
LIF MYH6 0 0 327 327 1 1
LIF DUSP9 0 0 165 165 1 1
LIF ITGB1 0 0 318 347 1 1
LIF PGK1 0 0 180 181 1 2
LIF ILF3 0 0 54 198 1 1
LIF STMN2 0 0 82 173 1 1
LIF ELAVL1 0 0 59 160 1 2
LIF IL16 0 0 294 294 1 1
LIF LEPR 0 600 285 703 1 1
LIF SNAI2 0 0 212 248 1 1
LIF CCL2 0 900 506 951 1 2
LIF CNTFR 0 600 610 862 1 1
LIF CD68 0 0 202 202 1 2
LIF ALB 0 0 517 567 1 2
LIF SPARC 0 0 218 218 1 2
LIF SOX15 0 0 112 172 1 1
LIF SMAD3 0 0 215 238 1 2
LIF IL17F 0 900 204 916 1 1
LIF TUBB3 0 0 324 396 1 1
LIF CNTF 0 0 914 917 1 1
LIF PDGFRB 0 600 240 683 1 2
LIF LEF1 0 0 218 218 1 1
LIF EP300 0 0 210 210 1 2
LIF IL4 0 0 504 515 1 1
LIF WNT9B 0 0 181 181 1 1
LIF IL27 0 0 208 208 1 1
LIF IL9 0 0 403 403 1 1
LIF FNDC5 0 0 340 340 1 1
LIF PLG 0 0 217 223 1 1
LIF LEFTY2 0 0 309 309 1 1
LIF ALCAM 0 0 210 225 1 1
LIF ZEB2 0 0 156 155 1 1
LIF PDGFRA 0 600 290 706 1 1
LIF NEUROG2 0 0 281 281 1 1
LIF FGF17 0 0 53 466 1 1
LIF CDH1 0 0 392 392 1 2
LIF BMP7 0 0 322 321 1 1
LIF GLI2 0 0 143 161 1 2
LIF HIST1H4E 0 0 181 181 1 1
LIF ACTC1 0 0 136 169 1 1
LIF NEUROG3 0 0 222 222 1 1
LIF WNT16 0 0 174 173 1 1
LIF NEFL 0 0 154 169 1 1
LIF IL1A 0 900 595 960 1 1
LIF CCL4 0 900 393 937 1 1
LIF CRYGC 0 0 284 284 1 1
LIF ACVR2B 0 0 163 178 1 1
LIF SUZ12 0 0 307 307 1 1
LIF WNT1 0 0 263 263 1 2
LIF PAX6 0 0 460 497 1 1
LIF NODAL 0 0 243 243 1 1
LIF GATA1 0 0 218 218 1 1
LIF EREG 0 0 233 249 1 1
LIF DPP4 0 0 134 152 1 1
LIF OMG 0 0 170 169 1 1
LIF CTGF 0 0 241 277 1 1
LIF DPPA4 0 0 270 270 1 1
LIF HES5 0 0 278 278 1 1
LIF FSTL3 0 0 54 151 1 1
LIF PDGFA 0 0 260 265 1 1
LIF CISH 0 0 457 457 1 1
LIF IL2RG 0 600 157 648 1 1
LIF NR3C1 0 0 156 155 1 1
LIF KLF5 0 0 341 380 1 2
LIF MAPRE3 0 0 213 213 1 1
LIF HIST2H3PS2 0 0 384 394 1 1
LIF FGF18 0 0 358 463 1 1
LIF CALCA 0 0 246 245 1 1
LIF TBX3 0 0 511 533 1 1
LIF PSPN 0 0 248 248 1 1
LIF ADIPOQ 0 0 167 167 1 2
LIF NANOS3 0 0 183 183 1 1
LIF FZD7 0 0 90 182 1 1
LIF VIM 0 0 180 196 1 2
LIF ARG1 0 0 177 177 1 2
LIF ZNF296 0 0 184 183 1 1
LIF BMP1 0 0 128 170 1 1
LIF EGF 0 0 681 702 1 2
LIF BMP2 0 0 407 443 1 1
LIF IL17A 0 900 451 942 1 2
LIF PLAU 0 0 122 295 1 1
LIF IGFBP1 0 0 287 286 1 1
LIF HNF1A 0 0 142 160 1 1
LIF POMC 0 900 382 935 1 1
LIF NANOG 0 0 739 768 1 2
LIF SLC1A2 0 0 174 173 1 1
LIF CXCL11 0 0 181 181 1 1
LIF IL13RA2 0 600 0 600 1 1
LIF CYCS 0 0 166 165 1 2
LIF DAB2 0 0 155 175 1 1
LIF CCR2 0 0 185 185 1 2
LIF LHX8 0 0 150 176 1 1
LIF CEBPD 0 0 183 201 1 1
LIF MYCL 0 0 163 168 1 1
LIF CHAT 0 0 392 392 1 1
LIF NES 0 0 609 648 1 2
LIF CXCL9 0 0 390 403 1 1
LIF IL12B 0 900 0 900 1 1
LIF IER3 0 0 134 262 1 1
LIF TEK 0 0 235 235 1 1
LIF PPARA 0 0 167 230 1 2
LIF PMEL 0 0 48 426 1 1
LIF GATA4 0 0 520 555 1 2
LIF LTF 0 0 150 158 1 1
LIF TYR 0 0 75 279 1 2
LIF PLAUR 0 0 202 249 1 1
LIF IL12RB2 0 600 0 600 1 1
LIF DICER1 0 0 240 239 1 1
LIF SNRPN 0 0 172 172 1 1
LIF JUN 0 0 380 380 1 2
LIF TYK2 0 600 420 763 1 1
LIF FZD1 0 0 113 173 1 1
LIF CDH17 0 0 202 202 1 1
LIF IL10RA 0 600 114 630 1 1
LIF WDR5 0 0 149 168 1 1
LIF CYP19A1 0 0 218 218 1 2
LIF NR2F2 0 0 251 278 1 1
LIF CALB1 0 0 161 161 1 1
LIF SRF 0 0 137 169 1 1
LIF AIF1 0 0 218 218 1 2
LIF TNFSF10 0 0 204 204 1 2
LIF ERBB4 0 0 146 486 1 1
LIF CAV1 0 0 112 202 1 2
LIF ZFP36 0 0 87 187 1 1
LIF ZBTB16 0 0 184 183 1 1
LIF JAK3 0 0 304 313 1 1
LIF CXCL6 0 0 166 228 1 1
LIF NNMT 0 0 81 198 1 1
LIF DNTT 0 0 211 211 1 1
LIF CCNA2 0 0 156 155 1 1
LIF ALOX15B 0 900 0 900 1 1
LIF ID4 0 0 170 169 1 1
LIF TRO 0 0 156 155 1 1
LIF ZP3 0 0 179 185 1 1
LIF ANGPT2 0 0 171 171 1 1
LIF KRT8 0 0 212 240 1 1
LIF IL22RA2 0 600 0 600 1 1
LIF MMP2 0 900 288 928 1 2
LIF DND1 0 0 150 170 1 1
LIF IGFBP3 0 0 181 244 1 2
LIF DLL1 0 0 204 204 1 1
LIF RAB27A 0 0 0 256 1 1
LIF SMAD1 0 0 212 230 1 2
LIF BMP6 0 0 181 181 1 1
LIF GAP43 0 0 240 239 1 1
LIF CD8A 0 0 321 321 1 1
LIF LTA 0 0 369 395 1 1
LIF BMI1 0 0 260 260 1 1
LIF CCR5 0 0 156 155 1 1
LIF IL7R 0 600 113 630 1 1
LIF SOX17 0 0 501 535 1 1
LIF SHH 0 0 460 483 1 2
LIF FGF6 0 0 64 473 1 1
LIF FYN 0 0 138 156 1 1
LIF ASCL2 0 0 155 154 1 1
LIF TET3 0 0 232 231 1 1
LIF IGFBP4 0 0 100 152 1 1
LIF NKX2-2 0 0 241 240 1 1
LIF GRB2 0 900 185 915 1 1
LIF FST 0 0 234 253 1 1
LIF JAG1 0 0 288 313 1 1
LIF ICAM1 0 0 321 361 1 2
LIF FOXD3 0 0 284 284 1 1
LIF OCA2 0 0 0 422 1 1
LIF BOLL 0 0 160 208 1 1
LIF IL22 0 0 330 330 1 1
LIF SOX9 0 0 289 306 1 1
LIF DPPA3 0 0 342 342 1 1
LIF ZEB1 0 0 184 183 1 2
LIF ENSG00000258724 0 0 261 262 1 1
LIF CD24 0 0 261 261 1 2
LIF NEUROG1 0 0 216 217 1 1
LIF PTPRC 0 0 407 410 1 1
LIF LMX1A 0 0 151 150 1 1
LIF GDF3 0 0 232 231 1 1
LIF ESR2 0 0 193 193 1 1
LIF SOHLH2 0 0 150 165 1 1
LIF MIXL1 0 0 321 321 1 1
LIF ITGAV 0 0 174 198 1 1
LIF FGF4 0 0 629 640 1 1
LIF TIMP1 0 900 335 934 1 1
LIF CXCL12 0 0 470 470 1 2
LIF POU3F1 0 0 180 179 1 1
LIF CRLF2 0 600 0 600 1 1
LIF TNNI3 0 0 167 167 1 1
LIF KDM1A 0 0 164 163 1 2
LIF GNRH1 0 0 253 252 1 1
LIF AR 0 0 181 181 1 2
LIF MBD3 0 0 143 166 1 1
LIF RHOA 0 0 214 214 1 2
LIF EPCAM 0 0 243 242 1 2
LIF IFNAR2 0 600 0 600 1 1
LIF ERAS 0 0 218 224 1 1
LIF SPP1 0 0 340 340 1 2
LIF CDKN1A 0 0 217 284 1 2
LIF SOX21 0 0 134 157 1 1
LIF VSX2 0 0 155 154 1 1
LIF HIST1H4J 0 0 181 181 1 1
LIF GLI3 0 0 170 189 1 1
LIF ACR 0 0 208 218 1 1
LIF MAPK3 0 0 423 422 1 2
LIF MMP9 0 900 338 932 1 2
LIF B2M 0 0 183 183 1 1
LIF PROM1 0 0 454 464 1 2
LIF THY1 0 0 416 416 1 1
LIF ANGPT1 0 0 260 260 1 1
LIF SELL 0 0 174 173 1 1
LIF HIST2H2AA 0 0 186 186 1 1
LIF DNMT1 0 0 370 375 1 2
LIF PRDM14 0 0 406 406 1 1
LIF CD40 0 0 228 244 1 2
LIF TES 0 0 123 158 1 1
LIF FGF1 0 0 362 362 1 1
LIF WNT6 0 0 212 212 1 1
LIF ACTB 0 0 505 525 1 2
LIF NOBOX 0 0 240 239 1 1
LIF INS 0 0 556 600 1 2
LIF NEFH 0 0 414 414 1 1
LIF FOXG1 0 0 180 179 1 1
LIF SUV39H1 0 0 167 167 1 1
LIF CRP 0 0 233 249 1 2
LIF NEUROD1 0 0 261 261 1 1
LIF SOX2 0 0 701 731 1 2
LIF CEBPA 0 0 195 195 1 1
LIF HPGDS 238 0 150 324 1 1
LIF IL21 0 0 0 303 1 1
LIF E2F7 0 0 103 226 1 1
LIF HIST2H2AA3 0 0 186 186 1 1
LIF FOSL1 0 0 113 358 1 1
LIF IL3 0 0 561 561 1 1
LIF PAX8 0 0 117 161 1 1
LIF HSP90AA1 0 0 142 151 1 2
LIF DDX4 0 0 267 282 1 1
LIF SETDB1 0 0 211 211 1 1
LIF LBP 0 900 0 900 1 1
LIF DNMT3L 0 0 310 309 1 1
LIF NRG1 0 0 217 218 1 2
LIF DCX 0 0 274 280 1 1
LIF HIST1H4D 0 0 181 181 1 1
LIF IL32 0 0 170 189 1 1
LIF HMOX1 0 0 260 287 1 2
LIF FOXP3 0 0 269 269 1 2
LIF ANPEP 0 0 171 213 1 1
LIF RNF2 0 0 216 216 1 1
LIF JAK1 0 600 604 835 1 2
LIF KDR 0 0 408 419 1 2
LIF HMMR 0 0 53 154 1 1
LIF SEMA3F 0 0 150 182 1 1
LIF YY1 0 0 160 159 1 1
LIF STAT5B 0 0 369 392 1 1
LIF TGFB1 0 900 325 936 1 2
LIF KRT19 0 0 184 215 1 1
LIF MSX2 0 0 185 311 1 1
LIF GLUL 0 0 151 174 1 1
LIF USP7 0 0 113 151 1 1
LIF CTCF 0 0 216 216 1 1
LIF TXLNA 0 0 215 215 1 1
LIF MMP10 0 0 88 158 1 1
LIF IL11RA 0 600 167 661 1 1
LIF APOE 0 0 169 169 1 2
LIF FOXO3 0 0 164 163 1 2
LIF IL26 0 0 155 156 1 1
LIF LIFR 675 800 907 993 1 1
LIF OXT 0 0 167 167 1 1
LIF KDM6A 0 0 170 169 1 1
LIF ITGA6 0 0 245 262 1 1
LIF TNFSF11 0 0 294 294 1 2
LIF IGFALS 0 0 63 231 1 1
LIF BGLAP 0 0 269 269 1 1
LIF SMARCC1 0 0 166 165 1 1
LIF EED 0 0 310 309 1 1
LIF ACRBP 0 0 0 300 1 1
LIF SRC 0 0 379 401 1 2
LIF DKK1 0 0 325 358 1 1
LIF PODXL 0 0 165 175 1 1
LIF HP 0 0 218 218 1 1
LIF IRF8 0 0 125 159 1 1
LIF TCL1A 0 0 325 341 1 1
LIF FLT1 0 0 230 229 1 1
LIF IL19 0 0 181 181 1 1
LIF TRIM28 0 0 162 161 1 2
LIF TLR3 0 0 206 206 1 2
LIF SEMA4F 0 0 154 153 1 1
LIF LGALS3 0 0 170 206 1 2
LIF MIF 0 0 370 370 1 2
LIF SRXN1 0 0 54 232 1 1
LIF STAT6 0 0 262 370 1 1
LIF HNF4A 0 0 293 293 1 1
LIF A2M 0 0 167 167 1 1
LIF MAG 0 0 217 228 1 1
LIF GSK3A 0 0 61 155 1 1
LIF FOXH1 0 0 146 163 1 1
LIF IFNGR2 0 600 404 751 1 1
LIF GJA1 0 0 294 294 1 1
LIF ZSCAN4 0 0 423 422 1 1
LIF BMP8B 0 0 181 191 1 1
LIF ID2 0 0 212 212 1 1
LIF NID1 0 0 213 232 1 1
LIF MYOF 0 0 0 154 1 1
LIF IL11 0 0 763 771 1 1
LIF RTN4 0 0 167 167 1 1
LIF EDNRB 0 0 97 295 1 1
LIF GGNBP2 0 0 166 165 1 1
LIF KRT18 0 0 216 256 1 1
LIF CXCL10 0 900 417 940 1 2
LIF FGF3 0 0 74 479 1 1
LIF FBXO15 0 0 324 323 1 1
LIF RBBP5 0 0 136 154 1 1
LIF PITX3 0 0 151 209 1 1
LIF IGF2R 0 0 750 750 1 1
LIF NR5A2 0 0 310 329 1 1
LIF IL6ST 967 800 569 997 1 1
LIF SLIT3 0 0 113 151 1 1
LIF CCL3L3 0 900 0 900 1 1
LIF TH 0 0 372 372 1 2
LIF ACVR1B 0 0 155 188 1 1
LIF ERBB2 0 0 205 327 1 2
LIF CD34 0 0 468 471 1 2
LIF NGF 0 0 601 615 1 2
LIF IL12RB1 0 600 166 652 1 1
LIF CSF2 0 900 565 957 1 1
LIF PREX2 0 0 0 190 1 1
LIF LHX2 0 0 134 152 1 1
LIF MKI67 0 0 47 183 1 2
LIF TEAD2 0 0 161 161 1 1
LIF TGFB2 0 0 324 348 1 1
LIF LHX3 0 0 150 173 1 1
LIF AKT1 0 0 521 532 1 2
LIF SLIT2 0 0 85 165 1 1
LIF PPARG 0 0 281 294 1 2
LIF HIST1H4C 0 0 181 181 1 1
LIF CD4 0 0 391 390 1 2
LIF HOXA10 0 0 506 506 1 1
LIF VCAM1 0 0 325 325 1 1
LIF SEMA7A 0 0 147 178 1 1
LIF LAMB3 0 0 0 213 1 1
LIF PTHLH 0 0 205 234 1 1
LIF FOXA1 0 0 107 163 1 1
LIF KLF4 0 0 681 728 1 2
LIF FGFR1 0 0 234 234 1 1
LIF VIP 0 0 324 323 1 1
LIF NTRK2 0 0 249 262 1 1
LIF SHC2 0 0 0 189 1 1
LIF RUNX2 0 0 258 258 1 2
LIF IFNLR1 0 600 0 600 1 1
LIF DROSHA 0 0 142 162 1 1
LIF NUP210 0 0 0 323 1 1
LIF SEMA4D 0 0 157 156 1 1
LIF MSX1 0 0 297 552 1 1
LIF TECPR2 0 0 0 303 1 2
LIF TNF 0 900 523 952 1 2
LIF RPAP1 0 0 92 183 1 1
LIF HNRNPD 0 0 57 158 1 1
LIF WISP1 0 0 95 176 1 1
LIF NR4A2 0 0 202 216 1 1
LIF MMP3 0 900 252 925 1 1
LIF IL1RN 0 0 240 239 1 1
LIF TDG 0 0 113 249 1 1
LIF NT5E 0 0 325 391 1 1
LIF IL7 0 0 502 502 1 1
LIF DCT 0 0 69 440 1 1
LIF GPR125 0 0 170 307 1 1
LIF SIN3A 0 0 145 163 1 1
LIF BDNF 0 0 594 611 1 2
LIF CD44 0 0 427 463 1 2
LIF MEF2C 0 0 292 292 1 1
LIF MMP7 0 0 150 188 1 1
LIF PAX3 0 0 243 245 1 1
LIF IL23R 0 600 135 639 1 1
LIF RBFOX3 0 0 291 290 1 1
LIF ACVR2A 0 0 90 152 1 1
LIF TFAP2C 0 0 195 195 1 1
LIF SOS1 0 900 0 900 1 1
LIF NR0B1 0 0 325 340 1 1
LIF TNNT2 0 0 261 261 1 1
LIF GCG 0 0 170 169 1 1
LIF AXIN2 0 0 167 167 1 1
LIF IL1R2 0 0 112 381 1 1
LIF IL5 0 0 405 405 1 1
LIF VWF 0 0 219 238 1 1
LIF CCND2 0 0 142 150 1 1
LIF IFNAR1 0 600 95 622 1 1
LIF HIST1H4H 0 0 181 181 1 1
LIF TNFAIP6 0 0 260 278 1 1
LIF TFRC 0 0 134 153 1 1
LIF GPNMB 0 0 70 151 1 1
LIF PRLR 0 600 90 620 1 1
LIF CXCL3 0 0 212 319 1 1
LIF FGF2 0 900 758 981 1 2
LIF CD9 0 0 233 252 1 1
LIF IL31RA 0 0 213 644 1 1
LIF ENSG00000196136 0 0 156 157 1 1
LIF RETN 0 0 186 186 1 1
LIF CDH5 0 0 292 292 1 1
LIF ATF3 0 0 193 223 1 2
LIF ESRRB 0 0 561 605 1 1
LIF KHDC3L 0 0 195 196 1 1
LIF CNR1 0 0 113 186 1 1
LIF GADD45A 0 0 123 155 1 1
LIF CCND3 0 0 139 161 1 1
LIF GCM1 0 0 167 173 1 1
LIF SOCS1 0 0 343 363 1 1
LIF IGF1 0 900 560 955 1 2
LIF ITGA3 0 0 91 170 1 2
LIF MAPK1 0 0 181 186 1 2
LIF SOCS4 0 0 296 296 1 1
LIF TBX18 0 0 398 398 1 1
LIF CSF1R 0 0 231 230 1 1
LIF CDK1 0 0 154 153 1 2
LIF MUC1 0 0 241 286 1 1
LIF HIST1H4B 0 0 181 181 1 1
LIF PGR 0 0 361 375 1 1
LIF HIST2H2BE 0 0 240 239 1 1
LIF PRKDC 0 0 66 210 1 2
LIF AHR 0 0 134 161 1 2
LIF SERPINE1 0 0 228 335 1 1
LIF CRLF1 0 0 294 294 1 1
LIF ECEL1 0 0 207 207 1 1
LIF REM1 0 0 0 189 1 1
LIF OLIG2 0 0 457 469 1 1
LIF EGR2 0 0 171 191 1 1
LIF LOX 0 0 218 272 1 2
LIF NTRK1 0 0 284 284 1 1
LIF SCAI 0 0 141 190 1 1
LIF EPOR 0 600 206 670 1 1
LIF KLF1 0 0 138 335 1 1
LIF CD19 0 0 223 240 1 1
LIF WNT9A 0 0 167 167 1 1
LIF FGF5 0 0 520 570 1 1
LIF WNT8B 0 0 182 181 1 1
LIF ATR 0 0 49 195 1 2
LIF MYL2 0 0 137 190 1 1
LIF ABCG2 0 0 193 193 1 1
LIF FLT3LG 0 0 173 173 1 1
LIF FAM129B 0 0 0 156 1 1
LIF NR5A1 0 0 180 189 1 1
LIF NOS3 0 0 166 165 1 2
LIF ACTA2 0 0 156 208 1 1
LIF SEMA3A 0 0 213 231 1 1
LIF CCND1 0 0 325 369 1 2
LIF CSF2RB 0 600 0 609 1 1
LIF CD274 0 0 151 192 1 2
LIF MEIS1 0 0 137 155 1 1
LIF MTF2 0 0 182 181 1 1
LIF KLF9 0 0 294 294 1 1
LIF ETV2 0 0 134 175 1 1
LIF CTLA4 0 0 202 220 1 2
LIF CCL19 0 900 140 910 1 1
LIF LIN28A 0 0 464 500 1 1
LIF FGF16 0 0 0 461 1 1
LIF MLANA 0 0 0 461 1 1
LIF FOXA2 0 0 458 495 1 1
LIF CD38 0 0 156 155 1 2
LIF SMAD6 0 0 123 164 1 1
LIF MYB 0 0 166 165 1 1
LIF OPALIN 0 0 123 177 1 1
LIF HIST2H4B 0 0 181 181 1 1
LIF MDK 0 0 95 291 1 1
LIF HPRT1 0 0 324 335 1 1
LIF HGF 0 900 563 955 1 2
LIF FSTL1 0 0 260 279 1 1
LIF POU5F1 0 0 739 786 1 2
LIF BMPR2 0 0 151 163 1 1
LIF CCL1 0 0 181 181 1 1
LIF SYCP3 0 0 233 242 1 1
LIF WNT10B 0 0 166 165 1 1
LIF PECAM1 0 0 420 435 1 1
LIF NKX2-5 0 0 426 431 1 1
LIF MAPK7 0 0 217 217 1 1
LIF VEGFA 0 900 598 960 1 2
LIF NFIA 0 0 181 186 1 1
LIF CHL1 0 0 235 235 1 1
LIF MBP 0 0 323 323 1 2
LIF BMPR1A 0 0 188 188 1 1
LIF ID3 0 0 163 170 1 1
LIF SALL1 0 0 170 169 1 1
LIF PTEN 0 0 261 261 1 2
LIF NTRK3 0 0 181 198 1 1
LIF MYOD1 0 0 325 325 1 1
LIF GAPDHS 0 0 0 185 1 1
LIF CD200 0 0 155 154 1 1
LIF WT1 0 0 193 193 1 1
LIF BMP4 0 0 648 684 1 1
LIF TCF4 0 0 310 325 1 1
LIF COMMD3-BMI1 0 0 255 255 1 1
LIF NFKBIA 0 0 202 202 1 2
LIF KIT 0 0 426 440 1 2
LIF LEP 0 0 417 416 1 1
LIF MAPK14 0 0 165 200 1 2
LIF TIMP3 0 0 134 155 1 1
LIF ENSG00000258947 0 0 310 384 1 1
LIF IL21R 0 600 52 604 1 1
LIF ARTN 0 0 267 286 1 1
LIF CSF3R 0 600 195 666 1 1
LIF HIST1H4K 0 0 181 181 1 1
LIF HIST1H4A 0 0 181 181 1 1
LIF CDX2 0 0 394 435 1 1
LIF RAB27B 0 0 0 256 1 1
LIF NGFR 0 0 244 243 1 1
LIF IL23A 0 900 95 905 1 1
LIF AXIN1 0 0 164 163 1 1
LIF S1PR5 0 0 112 173 1 1
LIF IGF2 0 0 401 400 1 1
LIF ITGA2B 0 0 175 175 1 1
LIF NTF4 0 0 370 379 1 1
LIF ATM 0 0 150 241 1 2
LIF SHC1 0 900 167 918 1 1
LIF SMAD5 0 0 181 191 1 1
LIF SOX10 0 0 195 222 1 1
LIF RET 0 0 181 181 1 1
LIF FGF12 0 0 61 472 1 1
LIF MDM4 0 0 108 197 1 1
LIF LHCGR 0 0 134 161 1 1
LIF CCL22 0 900 181 914 1 1
LIF FCGR3B 0 0 154 153 1 1
LIF ENG 0 0 370 392 1 2
LIF CCL3 0 900 406 938 1 1
LIF WNT10A 0 0 162 161 1 1
LIF GLIS1 0 0 134 173 1 1
LIF TAC1 0 0 252 252 1 1
LIF TGFBR2 0 0 142 173 1 1
LIF DMD 0 0 113 168 1 2
LIF SELE 0 0 176 175 1 1
LIF RECQL4 0 0 0 206 1 1
LIF ACTG1 0 0 261 298 1 1
LIF GDF15 0 0 141 228 1 1
LIF FOSL2 0 0 577 597 1 1
LIF PREX1 0 0 0 190 1 1
LIF CCL20 0 900 268 931 1 1
LIF IL10 0 900 556 954 1 2
LIF SNAI1 0 0 269 304 1 1
LIF EFNB2 0 0 172 171 1 1
LIF GFAP 0 0 503 509 1 2
LIF GFRA1 0 0 322 321 1 1
LIF RYBP 0 0 150 168 1 1
LIF COL1A1 0 0 195 234 1 2
LIF CXCL2 0 900 283 932 1 1
LIF RBPJ 0 0 213 213 1 1
LIF FLT3 0 0 284 284 1 2
LIF SOCS6 0 0 253 252 1 1
LIF GALC 0 0 216 216 1 1
LIF TGFBR1 0 0 215 232 1 1
LIF NKX2-1 0 0 170 169 1 1
LIF S100A4 0 0 134 152 1 1
LIF IL22RA1 0 600 55 617 1 1
LIF TET2 0 0 234 240 1 2
LIF TERT 0 0 234 241 1 2
LIF GLI1 0 0 173 191 1 2
LIF TYRP1 0 0 81 241 1 1
LIF TIMP2 0 0 203 214 1 1
LIF XCL1 0 0 193 193 1 1
LIF MCAM 0 0 242 243 1 1
LIF TEAD4 0 0 163 212 1 1
LIF PIAS3 0 0 310 309 1 1
LIF STRA8 0 0 345 345 1 1
LIF NRTN 0 0 262 262 1 1
LIF HAND2 0 0 246 245 1 1
LIF SOD3 0 0 123 160 1 1
LIF THPO 0 0 451 451 1 1
LIF DPPA2 0 0 281 281 1 1
LIF COCH 0 0 123 177 1 1
LIF NCAM1 0 0 310 315 1 1
LIF HSD17B3 0 0 124 175 1 1
LIF GAL 0 0 310 309 1 1
LIF RARS 0 0 152 151 1 1
LIF RAG2 0 0 290 290 1 1
LIF FN1 0 0 517 549 1 2
LIF TBP 0 0 181 181 1 1
LIF VTN 0 0 288 288 1 1
LIF MMP13 0 0 161 161 1 2
LIF IL5RA 0 600 55 605 1 1
LIF CTF1 0 900 769 977 1 1
LIF PRL 0 0 395 394 1 1
LIF EOMES 0 0 323 341 1 1
LIF MCL1 0 0 167 167 1 2
LIF IL10RB 0 600 90 620 1 1
LIF DLK1 0 0 180 179 1 1
LIF MYOCD 0 0 193 193 1 1
LIF SIRT1 0 0 171 171 1 2
LIF SMARCA4 0 0 253 254 1 1
LIF ITGAM 0 0 323 323 1 1
LIF GATA2 0 0 241 253 1 1
LIF SMAD7 0 0 185 185 1 1
LIF T 0 0 0 516 1 1
LIF DIO3 0 0 181 192 1 1
LIF IFNB1 0 0 294 294 1 1
LIF ESR1 0 0 390 390 1 2
LIF EN1 0 0 180 179 1 1
LIF WNT3A 0 0 391 392 1 2
LIF KSR1 0 0 46 251 1 1
LIF ITGB3 0 0 218 256 1 1
LIF LGR5 0 0 193 193 1 1
LIF CRH 0 0 261 261 1 1
LIF SYP 0 0 171 171 1 1
LIF STAT2 0 0 217 346 1 1
LIF OTX2 0 0 391 404 1 1
LIF YAP1 0 0 91 158 1 2
LIF IRF1 0 0 156 155 1 2
LIF GATA6 0 0 470 510 1 1
LIF MPL 0 600 195 664 1 1
LIF PGF 0 0 278 278 1 1
LIF CSPG4 0 0 137 183 1 1
LIF SOX7 0 0 261 262 1 1
LIF CD86 0 0 213 222 1 1
LIF ERRFI1 0 0 92 241 1 1
LIF PIM3 0 0 107 151 1 1
LIF FGF23 0 0 90 278 1 1
LIF TLR2 0 0 235 235 1 2
LIF PMAIP1 0 0 89 182 1 2
LIF AMH 0 0 246 245 1 1
LIF MET 0 0 233 288 1 2
LIF TFCP2L1 0 0 339 350 1 1
LIF NR6A1 0 0 226 225 1 1
LIF CCL7 0 0 369 394 1 1
LIF PTGES 0 0 150 168 1 1
LIF THBS1 0 0 193 251 1 1
LIF ITGA2 0 0 108 151 1 1
LIF ADCY10 0 0 178 177 1 1
LIF IL2 0 0 459 459 1 1
LIF SFRP2 0 0 193 211 1 1
LIF ALDH1A1 0 0 180 179 1 1
LIF ZIC3 0 0 171 171 1 1
LIF KRAS 0 0 134 267 1 2
LIF FOXO1 0 0 182 181 1 2
LIF CCL17 0 0 165 165 1 1
LIF IFNGR1 0 600 432 763 1 1
LIF NANOS2 0 0 141 201 1 1
LIF PTH 0 0 167 167 1 1
LIF FGF20 0 0 95 432 1 1
LIF ASCL1 0 0 305 305 1 1
LIF KDM2B 0 0 180 180 1 1
LIF CCL8 0 0 193 193 1 1
LIF GAB1 0 0 307 307 1 1
LIF STAT5A 0 0 391 401 1 1
LIF ANGPTL4 0 0 125 156 1 1
LIF MYO5C 0 0 0 208 1 1
LIF AQP4 0 0 181 181 1 1
LIF ZFP42 0 0 464 467 1 1
LIF KCNG1 0 0 156 175 1 1
LIF MSTN 0 0 334 334 1 1
LIF PTPN11 0 0 394 394 1 1
LIF CCL27 0 0 285 284 1 1
LIF TWIST1 0 0 161 161 1 1
LIF FOS 0 0 374 374 1 2
LIF FASLG 0 0 181 181 1 1
LIF SOCS3 0 0 566 595 1 1
LIF IL31 0 0 505 505 1 1
LIF WNT3 0 0 241 242 1 1
LIF FGF11 0 0 54 468 1 1
LIF CSF1 0 0 466 497 1 1
LIF PRDM1 0 0 209 209 1 1
LIF HDAC1 0 0 241 241 1 2
LIF TSPO 0 0 174 198 1 1
LIF GHR 0 600 82 629 1 1
LIF BANF1 0 0 202 202 1 1
LIF IL13RA1 0 600 95 633 1 1
LIF SOX1 0 0 517 540 1 1
LIF CEBPB 0 0 266 301 1 2
LIF FGF9 0 0 210 493 1 1
LIF WNT2 0 0 183 327 1 1
LIF NTF3 0 0 508 526 1 1
LIF HMX3 0 0 413 412 1 1
LIF HIST2H4A 0 0 181 181 1 1
LIF KLF2 0 0 407 481 1 1
LIF FABP4 0 0 124 156 1 1
LIF ADM 0 0 163 195 1 2
LIF CDKN2A 0 0 194 214 1 2
LIF SOCS2 0 0 292 292 1 1
LIF SST 0 0 143 161 1 1
LIF BMPR1B 0 0 154 153 1 1
LIF S100B 0 0 322 321 1 1
LIF KRT7 0 0 127 215 1 1
LIF SALL4 0 0 393 415 1 1
LIF ITGAX 0 0 153 152 1 1
LIF MRC1 0 0 183 183 1 1
LIF GSK3B 0 0 260 456 1 2
LIF TTR 0 0 188 188 1 1
LIF FGF8 0 0 287 489 1 1
LIF CD28 0 0 157 175 1 1
LIF TET1 0 0 325 325 1 1
LIF VEGFC 0 0 181 229 1 1
LIF GDF11 0 0 148 170 1 1
LIF CXCL5 0 0 270 324 1 1
LIF IHH 0 0 340 359 1 1
LIF ANG 0 0 142 159 1 2
LIF FGF22 0 0 72 478 1 1
LIF NOTCH2 0 0 134 159 1 1
LIF IL13 0 0 413 412 1 2
LIF FIGF 0 0 168 167 1 1
LIF MYO5B 0 0 0 286 1 1
LIF AFP 0 0 413 472 1 2
LIF TUBB6 0 0 46 239 1 1
LIF F3 0 0 122 171 1 1
LIF CASP3 0 0 325 325 1 2
LIF ERBB3 0 0 108 302 1 1
LIF FGF19 0 0 59 471 1 1
LIF CYP26A1 0 0 184 183 1 1
LIF PTGS2 0 0 371 408 1 2
LIF CCL11 0 0 390 390 1 1
LIF APCS 0 0 81 221 1 1
LIF EGLN1 0 0 433 433 1 1
LIF IL33 0 0 184 183 1 2
LIF CXCL1 0 900 404 946 1 2
LIF MMP14 0 0 107 216 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0005125 Molecular Function cytokine activity enables IBA
GO:0005125 Molecular Function cytokine activity enables IDA
GO:0008083 Molecular Function growth factor activity enables IBA
GO:0008083 Molecular Function growth factor activity enables IDA
GO:0005146 Molecular Function leukemia inhibitory factor receptor binding enables IBA
GO:0005146 Molecular Function leukemia inhibitory factor receptor binding enables IDA
GO:0005146 Molecular Function leukemia inhibitory factor receptor binding enables IPI
GO:0005515 Molecular Function protein binding enables IPI
GO:0005102 Molecular Function signaling receptor binding enables IPI
GO:0001974 Biological Process blood vessel remodeling involved_in IEA
GO:0000902 Biological Process cell morphogenesis involved_in IEA
GO:0046697 Biological Process decidualization involved_in IEA
GO:0007566 Biological Process embryo implantation involved_in IEA
GO:0048144 Biological Process fibroblast proliferation involved_in IEA
GO:0010467 Biological Process gene expression involved_in IEA
GO:0006955 Biological Process immune response involved_in IEA
GO:0048861 Biological Process leukemia inhibitory factor signaling pathway involved_in IBA
GO:0048861 Biological Process leukemia inhibitory factor signaling pathway involved_in IDA
GO:0048286 Biological Process lung alveolus development involved_in IEA
GO:0060463 Biological Process lung lobe morphogenesis involved_in IEA
GO:0060426 Biological Process lung vasculature development involved_in IEA
GO:0030225 Biological Process macrophage differentiation involved_in TAS
GO:0140013 Biological Process meiotic nuclear division involved_in IEA
GO:0048644 Biological Process muscle organ morphogenesis involved_in IEA
GO:0070373 Biological Process negative regulation of ERK1 and ERK2 cascade involved_in IEA
GO:0008285 Biological Process negative regulation of cell population proliferation involved_in IEA
GO:0046888 Biological Process negative regulation of hormone secretion acts_upstream_of_or_within IDA
GO:0045835 Biological Process negative regulation of meiotic nuclear division involved_in IEA
GO:0048666 Biological Process neuron development involved_in IEA
GO:0043410 Biological Process positive regulation of MAPK cascade acts_upstream_of_or_within IDA
GO:0048711 Biological Process positive regulation of astrocyte differentiation involved_in IEA
GO:0033630 Biological Process positive regulation of cell adhesion mediated by integrin involved_in IMP
GO:0008284 Biological Process positive regulation of cell population proliferation involved_in IBA
GO:0008284 Biological Process positive regulation of cell population proliferation acts_upstream_of_or_within IDA
GO:0008284 Biological Process positive regulation of cell population proliferation involved_in IDA
GO:0048146 Biological Process positive regulation of fibroblast proliferation involved_in IEA
GO:0010628 Biological Process positive regulation of gene expression involved_in IEA
GO:0045651 Biological Process positive regulation of macrophage differentiation acts_upstream_of_or_within IDA
GO:0072108 Biological Process positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis involved_in IDA
GO:0033138 Biological Process positive regulation of peptidyl-serine phosphorylation acts_upstream_of_or_within IDA
GO:0033141 Biological Process positive regulation of peptidyl-serine phosphorylation of STAT protein involved_in IDA
GO:0050731 Biological Process positive regulation of peptidyl-tyrosine phosphorylation acts_upstream_of_or_within IDA
GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II acts_upstream_of_or_within IDA
GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II involved_in IDA
GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II involved_in IMP
GO:0042531 Biological Process positive regulation of tyrosine phosphorylation of STAT protein involved_in IDA
GO:0097696 Biological Process receptor signaling pathway via STAT involved_in IDA
GO:0045595 Biological Process regulation of cell differentiation involved_in IBA
GO:0072307 Biological Process regulation of metanephric nephron tubule epithelial cell differentiation involved_in IDA
GO:0001666 Biological Process response to hypoxia involved_in IEA
GO:0035019 Biological Process somatic stem cell population maintenance involved_in IEA
GO:0048863 Biological Process stem cell differentiation involved_in IEA
GO:0060707 Biological Process trophoblast giant cell differentiation involved_in IEA
GO:0005829 Cellular Component cytosol located_in IDA
GO:0005576 Cellular Component extracellular region located_in TAS
GO:0005615 Cellular Component extracellular space is_active_in IBA
GO:0005615 Cellular Component extracellular space located_in IC
Pathways
Name DB ID
Cytokine Signaling in Immune system Reactome R-HSA-1280215
Immune System Reactome R-HSA-168256
Signaling by Interleukins Reactome R-HSA-449147
Interleukin-6 family signaling Reactome R-HSA-6783589
Interleukin-10 signaling Reactome R-HSA-6783783
Interleukin-4 and Interleukin-13 signaling Reactome R-HSA-6785807
IL-6-type cytokine receptor ligand interactions Reactome R-HSA-6788467
Neuroinflammation and glutamatergic signaling (WP5083) WikiPathways WP5083_r120385
p53 transcriptional gene network (WP4963) WikiPathways WP4963_r122690
TGF-beta receptor signaling in skeletal dysplasias (WP4816) WikiPathways WP4816_r116440
Oligodendrocyte specification and differentiation, leading to myelin components for CNS (WP4304) WikiPathways WP4304_r123411
Overview of proinflammatory and profibrotic mediators (WP5095) WikiPathways WP5095_r120801
MicroRNAs in cardiomyocyte hypertrophy (WP1544) WikiPathways WP1544_r121713
Adipogenesis (WP236) WikiPathways WP236_r105873
TGF-beta receptor signaling (WP560) WikiPathways WP560_r117838
Embryonic stem cell pluripotency pathways (WP3931) WikiPathways WP3931_r117717
Transcripts
Accession Version MolecularType Name NCBI Comments
NM_001257135 2 mRNA transcript variant 2 NC_000022 Reference
NM_002309 5 mRNA transcript variant 1 NC_000022 Reference
XM_047441361 1 mRNA transcript variant X1 NC_000022 Reference