SMAD2

SMAD family member 2

General Information

Name	SMAD family member 2
Alias	mothers against decapentaplegic homolog 2 MAD homolog 2 SMAD, mothers against DPP homolog 2 Sma- and Mad-related protein 2 mother against DPP homolog 2
Gene_family	SMAD family
organism	Homo sapiens
entrez_id	4087
location	18q21.1
transcript_count	6
exon_count	14

Cross References

Location

by NCBI GRCh38.p14

Summary

Entrez The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signal of the transforming growth factor (TGF)-beta, and thus regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein. In response to TGF-beta signal, this protein is phosphorylated by the TGF-beta receptors. The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4. The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors. This protein can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012]

Stringdb Mothers against decapentaplegic homolog 2; Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator

nextProt Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.

Interactions

NCBI

A	A.Source	B	B.DB	B.Source	Description
SMAD2	BioGRID	TGOLN2	GeneID	BioGRID	Proximity Label-MS
SMAD2	BioGRID	ACVR1B	GeneID	BioGRID	Affinity Capture-Western; Biochemical Activity
SMAD2	BioGRID	SPPL3	GeneID	BioGRID	Positive Genetic
SMAD2	BioGRID	TRIM67	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	USP15	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	CCNF	GeneID	BioGRID	Proximity Label-MS
SMAD2	BioGRID	EZH2	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western
SMAD2	BioGRID	SMAD3	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Phenotypic Enhancement; Two-hybrid
SMAD2	BioGRID	PRKN	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	SMAD4	GeneID	BioGRID	Affinity Capture-Luminescence; Affinity Capture-MS; Affinity Capture-Western; Co-crystal Structure; Co-fractionation; Reconstituted Complex; Two-hybrid
SMAD2	BioGRID	TGFBR2	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	TGFBR1	GeneID	BioGRID	Affinity Capture-Western; Biochemical Activity; Co-fractionation; Co-localization
SMAD2	BioGRID	PARP1	GeneID	BioGRID	Co-fractionation
SMAD2	BioGRID	NAA15	GeneID	BioGRID	Co-fractionation
SMAD2	BioGRID	SNF8	GeneID	BioGRID	Co-fractionation
SMAD2	BioGRID	SUB1	GeneID	BioGRID	Co-fractionation
SMAD2	BioGRID	RBM14	GeneID	BioGRID	Co-fractionation
SMAD2	BioGRID	ZFYVE9	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Reconstituted Complex; Two-hybrid
SMAD2	BioGRID	MTA2	GeneID	BioGRID	Co-fractionation
SMAD2	BioGRID	AP1M1	GeneID	BioGRID	Co-fractionation
SMAD2	BioGRID	OVOL2	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	ARID1B	GeneID	BioGRID	Affinity Capture-MS; Co-fractionation
SMAD2	BioGRID	TRIM33	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Co-fractionation
SMAD2	BioGRID	PRKDC	GeneID	BioGRID	Co-fractionation
SMAD2	BioGRID	PML	GeneID	BioGRID	Affinity Capture-Western; Co-fractionation
SMAD2	BioGRID	HDAC1	GeneID	BioGRID	Affinity Capture-Western; Co-fractionation
SMAD2	BioGRID	XRCC6	GeneID	BioGRID	Co-fractionation
SMAD2	BioGRID	CTNNB1	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Co-fractionation
SMAD2	BioGRID	CREBBP	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Reconstituted Complex; Two-hybrid
SMAD2	BioGRID	NCOA3	GeneID	BioGRID	Affinity Capture-MS; Co-fractionation
SMAD2	BioGRID	HMGA2	GeneID	BioGRID	Co-fractionation
SMAD2	BioGRID	SMARCC2	GeneID	BioGRID	Affinity Capture-MS; Co-fractionation
SMAD2	BioGRID	SMARCC1	GeneID	BioGRID	Affinity Capture-MS; Co-fractionation
SMAD2	BioGRID	SMARCA4	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Co-fractionation
SMAD2	BioGRID	RELA	GeneID	BioGRID	Co-fractionation
SMAD2	BioGRID	SMURF2	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SMAD2	BioGRID	SNX27	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	RAB7A	GeneID	BioGRID	Proximity Label-MS
SMAD2	BioGRID	Paxip1	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	OPTN	GeneID	BioGRID	Proximity Label-MS
SMAD2	BioGRID	HGS	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	KAT2B	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD2	BioGRID	SKIL	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Two-hybrid
SMAD2	BioGRID	SKI	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SMAD2	BioGRID	SGSH	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	SMAD9	GeneID	BioGRID	Affinity Capture-MS; Two-hybrid
SMAD2	BioGRID	LDLRAD4	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	FYN	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	FLOT2	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	CGA	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	CDC27	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western
SMAD2	BioGRID	SMPDL3B	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	LEMD3	GeneID	BioGRID	Affinity Capture-MS; Two-hybrid
SMAD2	BioGRID	FLOT1	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	TMOD1	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	TMED8	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	HINT3	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	BTBD9	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	RIGI	GeneID	BioGRID	Affinity Capture-RNA
SMAD2	BioGRID	UCHL1	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	TRIM28	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western
SMAD2	BioGRID	AKT1	GeneID	BioGRID	Affinity Capture-Western; Two-hybrid
SMAD2	BioGRID	HSD17B3	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	CYLC2	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	RASA1	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	MAP2K1	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	orf1ab	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	FBP2	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	XPA	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	CORO2A	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	TRMO	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	DNAJB5	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	ZNF510	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	MED20	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	MED17	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	ASH2L	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	OGT	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	TAF6	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	TAF5	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	TAF2	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	TAF1	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	MED22	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	SMARCD2	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	HCFC1	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	GTF3C2	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	MEN1	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	MED15	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western
SMAD2	BioGRID	MED31	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	MED4	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	MED16	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	BCL7A	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	MED19	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	GTF3C6	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	TAF3	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	MED25	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	WDR82	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	KMT2C	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	MED9	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	E6	GeneID	BioGRID	PCA; Two-hybrid
SMAD2	BioGRID	E6	GeneID	BioGRID	PCA; Two-hybrid
SMAD2	BioGRID	FOXH1	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SMAD2	BioGRID	Zeb2	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	ezh2.L	GeneID	BioGRID	Co-localization
SMAD2	BioGRID	USP2	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	USP7	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	PLEKHA4	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	MTMR4	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	BECN1	GeneID	BioGRID	FRET
SMAD2	BioGRID	CUL4A	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	CUL4B	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	MYC	GeneID	BioGRID	Affinity Capture-Western; FRET; Reconstituted Complex; Two-hybrid
SMAD2	BioGRID	LATS2	GeneID	BioGRID	FRET
SMAD2	BioGRID	SMAD1	GeneID	BioGRID	Affinity Capture-MS; FRET; Two-hybrid
SMAD2	BioGRID	DYRK1A	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	HDAC2	GeneID	BioGRID	Affinity Capture-MS; Reconstituted Complex
SMAD2	BioGRID	Bach1	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	HYAL2	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD2	BioGRID	TP53	GeneID	BioGRID	Affinity Capture-Western; Co-localization; Reconstituted Complex
SMAD2	BioGRID	METTL3	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	METTL14	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	RBBP5	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	RELB	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	GSK3A	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	YAF2	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	HDAC4	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	PCBP1	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	MAPT	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	YAP1	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	NEDD4L	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SMAD2	BioGRID	SMAD7	GeneID	BioGRID	Affinity Capture-Western; Phenotypic Suppression; Reconstituted Complex
SMAD2	BioGRID	CAMK2A	GeneID	BioGRID	Co-localization
SMAD2	BioGRID	Aldh4a1	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	PARD3	GeneID	BioGRID	Reconstituted Complex
SMAD2	BioGRID	NFIA	GeneID	BioGRID	Reconstituted Complex
SMAD2	BioGRID	Dok1	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	RNF111	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	GLI1	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	EP300	GeneID	BioGRID	Affinity Capture-Western; Two-hybrid
SMAD2	BioGRID	LEF1	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD2	BioGRID	Sox9	GeneID	BioGRID	Reconstituted Complex
SMAD2	BioGRID	ANP32B	GeneID	BioGRID	Reconstituted Complex
SMAD2	BioGRID	TUBA1B	GeneID	BioGRID	Reconstituted Complex
SMAD2	BioGRID	SYT1	GeneID	BioGRID	Reconstituted Complex
SMAD2	BioGRID	SOD1	GeneID	BioGRID	Reconstituted Complex
SMAD2	BioGRID	ANP32E	GeneID	BioGRID	Reconstituted Complex
SMAD2	BioGRID	PTMS	GeneID	BioGRID	Reconstituted Complex
SMAD2	BioGRID	NEFM	GeneID	BioGRID	Reconstituted Complex
SMAD2	BioGRID	JUN	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD2	BioGRID	ATP5ME	GeneID	BioGRID	Reconstituted Complex
SMAD2	BioGRID	RHOA	GeneID	BioGRID	Reconstituted Complex
SMAD2	BioGRID	OTUB1	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
SMAD2	BioGRID	POLY	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	TSC2	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	FHL3	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD2	BioGRID	FHL2	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD2	BioGRID	FHL1	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD2	BioGRID	CSNK1D	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity
SMAD2	BioGRID	KLF5	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western
SMAD2	BioGRID	SH2D2A	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD2	BioGRID	LCK	GeneID	BioGRID	Reconstituted Complex
SMAD2	BioGRID	IRF7	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD2	BioGRID	IRF3	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	PIK3CA	GeneID	BioGRID	Reconstituted Complex
SMAD2	BioGRID	ST13	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	DENND2B	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	SRI	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	SPTBN1	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	SNRNP70	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	RXRA	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	RPS27A	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	RPS14	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	ROCK1	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	RARB	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	PEX19	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	PSMD11	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	PSMD8	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	PSG9	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	PSAP	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	PRKAR1A	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	PPP2R1A	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	PAPPA	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	NOTCH4	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	FAM161B	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	ANTXR2	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	DOCK8	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	ABTB1	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	C22orf46P	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	RNF123	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	GATAD2B	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	SMURF1	GeneID	BioGRID	Affinity Capture-Western; Two-hybrid
SMAD2	BioGRID	TGM2	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	BTBD2	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	RNPC3	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	NAGK	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	TRIM62	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	ZNHIT6	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	DCUN1D1	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	EIF3L	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	UBR5	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	ANAPC2	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	RANBP6	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	SNAPIN	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	WASHC4	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	TBC1D1	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	NCOA6	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	PAXIP1	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	BAZ1A	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	COPS5	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	OS9	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	PAPOLA	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	ZMYND11	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	KHDRBS1	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	PLIN3	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	RANBP9	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	ZEB2	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	CUL5	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	ZNF41	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	UBA52	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	DNAJC7	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	GFER	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	EEF1A1	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	DYNC1H1	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	CYP11A1	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	CSH2	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	CSH1	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	CISH	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	ANK3	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	AFDN	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	SMAD2	GeneID	BioGRID	Affinity Capture-Western; Two-hybrid
SMAD2	BioGRID	LAMA5	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	KPNB1	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	CDK4	GeneID	BioGRID	Biochemical Activity
SMAD2	BioGRID	CDK2	GeneID	BioGRID	Biochemical Activity
SMAD2	BioGRID	ELAC2	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD2	BioGRID	PIN1	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD2	BioGRID	CHUK	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	ERBIN	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
SMAD2	BioGRID	SNW1	GeneID	BioGRID	Affinity Capture-MS; Phenotypic Enhancement; Reconstituted Complex; Two-hybrid
SMAD2	BioGRID	U2AF2	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	WWP2	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western
SMAD2	BioGRID	DNAJA2	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	DCAF7	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	RIN1	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	BUB3	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	DDX3Y	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	YY1	GeneID	BioGRID	Affinity Capture-MS; Reconstituted Complex
SMAD2	BioGRID	S100A4	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	SLC25A3	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	OPA1	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	SMAD5	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	ITGB4	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	HSPA4	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	DHX8	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	DGKA	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	CCT6A	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	CAD	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	SLC25A6	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	SLC25A5	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	FAM83G	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	ATAD3B	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	CPSF7	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	C1orf116	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	SQOR	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	EPB41L5	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	WRNIP1	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	PCID2	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	PSPC1	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	SIK3	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	DOCK9	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western
SMAD2	BioGRID	ACVR2B	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	TCF12	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	ETV4	GeneID	BioGRID	Affinity Capture-Western; Two-hybrid
SMAD2	BioGRID	WWP1	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	RGCC	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	ELAVL1	GeneID	BioGRID	Affinity Capture-RNA
SMAD2	BioGRID	ITCH	GeneID	BioGRID	Affinity Capture-Western; Biochemical Activity
SMAD2	BioGRID	CDK9	GeneID	BioGRID	Biochemical Activity
SMAD2	BioGRID	CDK8	GeneID	BioGRID	Biochemical Activity
SMAD2	BioGRID	SP1	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SMAD2	BioGRID	USP9X	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	NUP214	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD2	BioGRID	STUB1	GeneID	BioGRID	Reconstituted Complex
SMAD2	BioGRID	ATF3	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	ESR1	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD2	BioGRID	Rnf111	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	KDM6B	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	ARID1A	GeneID	BioGRID	Affinity Capture-MS
SMAD2	BioGRID	KAT2A	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	SOX9	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	ING2	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	MECOM	GeneID	BioGRID	Reconstituted Complex
SMAD2	BioGRID	MED6	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	MED24	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	GTF2IRD1	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	GTF2I	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	MYOCD	GeneID	BioGRID	Reconstituted Complex
SMAD2	BioGRID	PIAS4	GeneID	BioGRID	Affinity Capture-Western; Two-hybrid
SMAD2	BioGRID	CITED2	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	PRDM16	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	POU2AF1	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	NEDD4	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	BPTF	GeneID	BioGRID	Reconstituted Complex
SMAD2	BioGRID	UCHL5	GeneID	BioGRID	Reconstituted Complex
SMAD2	Protein	Functional smad suppressing element 18	None	HPRD
SMAD2	Protein	TBC1D1	GeneID	HPRD
SMAD2	Protein	OS9	GeneID	HPRD
SMAD2	Protein	DCAF6	GeneID	HPRD
SMAD2	Protein	EID2	GeneID	HPRD
SMAD2	Protein	ANAPC10	GeneID	HPRD
SMAD2	Protein	STAMBPL1	GeneID	HPRD
SMAD2	Protein	PPM1A	GeneID	HPRD
SMAD2	Protein	PPP2R1A	GeneID	HPRD
SMAD2	Protein	GSC	GeneID	HPRD
SMAD2	Protein	RHEBL1	GeneID	HPRD
SMAD2	Protein	RASL12	GeneID	HPRD
SMAD2	Protein	RASD2	GeneID	HPRD
SMAD2	Protein	GATAD2B	GeneID	HPRD
SMAD2	Protein	BTBD2	GeneID	HPRD
SMAD2	Protein	NUAK2	GeneID	HPRD
SMAD2	Protein	MED15	GeneID	HPRD
SMAD2	Protein	DCUN1D1	GeneID	HPRD
SMAD2	Protein	BAZ1A	GeneID	HPRD
SMAD2	Protein	NEDD9	GeneID	HPRD
SMAD2	Protein	RNF123	GeneID	HPRD
SMAD2	Protein	EIF3L	GeneID	HPRD
SMAD2	Protein	ABTB1	GeneID	HPRD
SMAD2	Protein	PAPOLA	GeneID	HPRD
SMAD2	Protein	LITAF	GeneID	HPRD
SMAD2	Protein	RIT1	GeneID	HPRD
SMAD2	Protein	PSMD8	GeneID	HPRD
SMAD2	Protein	ZMYND11	GeneID	HPRD
SMAD2	Protein	LEMD3	GeneID	HPRD
SMAD2	Protein	RHOJ	GeneID	HPRD
SMAD2	Protein	TOB1	GeneID	HPRD
SMAD2	Protein	PIAS3	GeneID	HPRD
SMAD2	Protein	UBA52	GeneID	HPRD
SMAD2	Protein	PSG9	GeneID	HPRD
SMAD2	Protein	ZNHIT6	GeneID	HPRD
SMAD2	Protein	NAGK	GeneID	HPRD
SMAD2	Protein	ST13	GeneID	HPRD
SMAD2	Protein	CSH1	GeneID	HPRD
SMAD2	Protein	Hypothetical FLJ23584	None	HPRD
SMAD2	Protein	UNKL	GeneID	HPRD
SMAD2	Protein	TRIM62	GeneID	HPRD
SMAD2	Protein	ANTXR2	GeneID	HPRD
SMAD2	Protein	ANAPC2	GeneID	HPRD
SMAD2	Protein	LHX9	GeneID	HPRD
SMAD2	Protein	RARB	GeneID	HPRD
SMAD2	Protein	DNAJC7	GeneID	HPRD
SMAD2	Protein	SNIP1	GeneID	HPRD
SMAD2	Protein	TGFBRAP1	GeneID	HPRD
SMAD2	Protein	PIAS4	GeneID	HPRD
SMAD2	Protein	SMURF2	GeneID	HPRD
SMAD2	Protein	COPS5	GeneID	HPRD
SMAD2	Protein	KAT2B	GeneID	HPRD
SMAD2	Protein	RAB34	GeneID	HPRD
SMAD2	Protein	HUWE1	GeneID	HPRD
SMAD2	Protein	CAMK2A	GeneID	HPRD
SMAD2	Protein	ARFGAP3	GeneID	HPRD
SMAD2	Protein	UBR5	GeneID	HPRD
SMAD2	Protein	STUB1	GeneID	HPRD
SMAD2	Protein	SNAPIN	GeneID	HPRD
SMAD2	Protein	ERBIN	GeneID	HPRD
SMAD2	Protein	HIPK2	GeneID	HPRD
SMAD2	Protein	PARD3	GeneID	HPRD
SMAD2	Protein	RAB38	GeneID	HPRD
SMAD2	Protein	STAMBP	GeneID	HPRD
SMAD2	Protein	STRAP	GeneID	HPRD
SMAD2	Protein	ZEB2	GeneID	HPRD
SMAD2	Protein	RHOD	GeneID	HPRD
SMAD2	Protein	CDC40	GeneID	HPRD
SMAD2	Protein	NFYC	GeneID	HPRD
SMAD2	Protein	NCOA6	GeneID	HPRD
SMAD2	Protein	PSMD11	GeneID	HPRD
SMAD2	Protein	HGS	GeneID	HPRD
SMAD2	Protein	STAG1	GeneID	HPRD
SMAD2	Protein	NUP153	GeneID	HPRD
SMAD2	Protein	RANBP9	GeneID	HPRD
SMAD2	Protein	AXIN1	GeneID	HPRD
SMAD2	Protein	ZFYVE9	GeneID	HPRD
SMAD2	Protein	FOXH1	GeneID	HPRD
SMAD2	Protein	CDC16	GeneID	HPRD
SMAD2	Protein	IRAK2	GeneID	HPRD
SMAD2	Protein	SMAD9	GeneID	HPRD
SMAD2	Protein	SMAD3	GeneID	HPRD
SMAD2	Protein	SNW1	GeneID	HPRD
SMAD2	Protein	MED6	GeneID	HPRD
SMAD2	Protein	MAPK9	GeneID	HPRD
SMAD2	Protein	KPNB1	GeneID	HPRD
SMAD2	Protein	PLIN3	GeneID	HPRD
SMAD2	Protein	EP300	GeneID	HPRD
SMAD2	Protein	FOXO3	GeneID	HPRD
SMAD2	Protein	TGIF1	GeneID	HPRD
SMAD2	Protein	PAK1	GeneID	HPRD
SMAD2	Protein	KHDRBS1	GeneID	HPRD
SMAD2	Protein	CISH	GeneID	HPRD
SMAD2	Protein	TP73	GeneID	HPRD
SMAD2	Protein	MAPK3	GeneID	HPRD
SMAD2	Protein	CUL5	GeneID	HPRD
SMAD2	Protein	ROCK1	GeneID	HPRD
SMAD2	Protein	GTF2I	GeneID	HPRD
SMAD2	Protein	ESR2	GeneID	HPRD
SMAD2	Protein	SQSTM1	GeneID	HPRD
SMAD2	Protein	SMAD2	GeneID	HPRD
SMAD2	Protein	DVL1	GeneID	HPRD
SMAD2	Protein	ACVR1B	GeneID	HPRD
SMAD2	Protein	HDAC1	GeneID	HPRD
SMAD2	Protein	DAB2	GeneID	HPRD
SMAD2	Protein	RAN	GeneID	HPRD
SMAD2	Protein	MAPK8	GeneID	HPRD
SMAD2	Protein	LAMA5	GeneID	HPRD
SMAD2	Protein	SMAD4	GeneID	HPRD
SMAD2	Protein	SMAD4	GeneID	HPRD
SMAD2	Protein	ARL4D	GeneID	HPRD
SMAD2	Protein	MEF2C	GeneID	HPRD
SMAD2	Protein	MEF2A	GeneID	HPRD
SMAD2	Protein	E2F4	GeneID	HPRD
SMAD2	Protein	ANK3	GeneID	HPRD
SMAD2	Protein	HNF4A	GeneID	HPRD
SMAD2	Protein	PEX19	GeneID	HPRD
SMAD2	Protein	RUNX2	GeneID	HPRD
SMAD2	Protein	AP1B1	GeneID	HPRD
SMAD2	Protein	CREBBP	GeneID	HPRD
SMAD2	Protein	DYNC1H1	GeneID	HPRD
SMAD2	Protein	ZNF41	GeneID	HPRD
SMAD2	Protein	GRIPAP1	GeneID	HPRD
SMAD2	Protein	ARHGEF6	GeneID	HPRD
SMAD2	Protein	ZNF8	GeneID	HPRD
SMAD2	Protein	RPS27A	GeneID	HPRD
SMAD2	Protein	TP53	GeneID	HPRD
SMAD2	Protein	TSC2	GeneID	HPRD
SMAD2	Protein	TNNT1	GeneID	HPRD
SMAD2	Protein	TGM2	GeneID	HPRD
SMAD2	Protein	TGFBR1	GeneID	HPRD
SMAD2	Protein	MYC	GeneID	HPRD
SMAD2	Protein	ZEB1	GeneID	HPRD
SMAD2	Protein	SP1	GeneID	HPRD
SMAD2	Protein	PRKAR1A	GeneID	HPRD
SMAD2	Protein	SRI	GeneID	HPRD
SMAD2	Protein	SNRNP70	GeneID	HPRD
SMAD2	Protein	LMO2	GeneID	HPRD
SMAD2	Protein	RXRA	GeneID	HPRD
SMAD2	Protein	MAPK1	GeneID	HPRD
SMAD2	Protein	PSAP	GeneID	HPRD
SMAD2	Protein	PAPPA	GeneID	HPRD
SMAD2	Protein	SKIL	GeneID	HPRD
SMAD2	Protein	GLI3	GeneID	HPRD
SMAD2	Protein	JUN	GeneID	HPRD
SMAD2	Protein	NOTCH4	GeneID	HPRD
SMAD2	Protein	FOXG1	GeneID	HPRD
SMAD2	Protein	SKI	GeneID	HPRD
SMAD2	Protein	AKT1	GeneID	HPRD
SMAD2	Protein	AFDN	GeneID	HPRD
SMAD2	Protein	LEF1	GeneID	HPRD
SMAD2	Protein	INSR	GeneID	HPRD
SMAD2	Protein	HOXD13	GeneID	HPRD
SMAD2	Protein	HOXA13	GeneID	HPRD
SMAD2	Protein	HOXA9	GeneID	HPRD
SMAD2	Protein	DENND2B	GeneID	HPRD
SMAD2	Protein	ESR1	GeneID	HPRD
SMAD2	Protein	RPS14	GeneID	HPRD
SMAD2	Protein	EEF1A1	GeneID	HPRD
SMAD2	Protein	CDK4	GeneID	HPRD
SMAD2	Protein	FBN2	GeneID	HPRD
SMAD2	Protein	CYP11A1	GeneID	HPRD
SMAD2	Protein	RBL1	GeneID	HPRD
SMAD2	Protein	CDC27	GeneID	HPRD
SMAD2	Protein	CTNNB1	GeneID	HPRD
SMAD2	Protein	NUP214	GeneID	HPRD
SMAD2	Protein	BRCA1	GeneID	HPRD
SMAD2	BioGRID	SMAD6	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	STRAP	GeneID	BioGRID	Affinity Capture-Western; Phenotypic Suppression
SMAD2	BioGRID	NEDD9	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	CAV1	GeneID	BioGRID	Co-fractionation
SMAD2	BioGRID	NFYC	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	MEF2C	GeneID	BioGRID	Reconstituted Complex
SMAD2	BioGRID	MEF2A	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD2	BioGRID	INSR	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SMAD2	BioGRID	RUNX3	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	RUNX1	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	RUNX2	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	CAMK2G	GeneID	BioGRID	Biochemical Activity
SMAD2	BioGRID	CDC16	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	TGIF1	GeneID	BioGRID	Affinity Capture-Western; Two-hybrid
SMAD2	BioGRID	DAB2	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD2	BioGRID	SNIP1	GeneID	BioGRID	Two-hybrid
SMAD2	BioGRID	DVL1	GeneID	BioGRID	Reconstituted Complex
SMAD2	BioGRID	ZEB1	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	HIPK2	GeneID	BioGRID	Reconstituted Complex
SMAD2	BioGRID	EID2	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	PIAS3	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD2	BioGRID	ANAPC10	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD2	BioGRID	BRCA2	GeneID	BioGRID	Affinity Capture-Western
SMAD2	BioGRID	Irak2	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD2	BioGRID	Arl4d	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD2	BioGRID	Rhoj	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD2	BioGRID	Rps27a	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD2	BioGRID	Rasd2	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD2	BioGRID	Nuak2	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD2	BioGRID	Arhgef6	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD2	BioGRID	Rab38	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD2	BioGRID	Cdc40	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD2	BioGRID	Rhobtb1	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD2	BioGRID	Rhebl1	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD2	BioGRID	Wwp2	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD2	BioGRID	Trim35	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD2	BioGRID	Fbxo3	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD2	BioGRID	Arhgef7	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD2	BioGRID	Ppp2r2d	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD2	BioGRID	Rgs3	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD2	BioGRID	Map2k3	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD2	BioGRID	Rab34	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD2	BioGRID	Sqstm1	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD2	BioGRID	Smad3	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD2	BioGRID	Smad2	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD2	BioGRID	Lmo2	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD2	BioGRID	Lhx9	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD2	BioGRID	Arhgef1	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD2	BioGRID	Uhmk1	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD2	BioGRID	Rhod	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD2	Protein	CREBBP	GeneID	BIND	CBP interacts with Smad2. This interaction was modeled on a demonstrated interaction between mouse CBP and Smad2 from an unspecified species.
SMAD2	Protein	FOXH1	GeneID	BIND	The SIM motif of FoxH1 interacts with Smad2. This interaction was modeled on a demonstrated interaction between human FoxH1 and Smad2 from an unspecified species.
SMAD2	Protein	SMAD3	GeneID	BIND	Smad2 interacts with Smad3. This interaction was modeled on a demonstrated interaction between Smad2 from an unspecified species and Smad3 from an unspecified species.
SMAD2	Protein	SMAD4	GeneID	BIND	Smad2 interacts with Smad4. This interaction was modeled on a demonstrated interaction between Smad2 from an unspecified species and Smad4 from an unspecified species.
SMAD2	Protein	CREBBP	GeneID	BIND	CBP interacts with Smad2. This interaction was modeled on a demonstrated interaction between CBP from an unspecified species and human Smad2.
SMAD2	Protein	EP300	GeneID	BIND	p300 interacts with Smad2. This interaction was modeled on a demonstrated interaction between p300 from an unspecified species and human Smad2.
SMAD2	Protein	SMAD4	GeneID	BIND	Smad4 interacts with Smad2.
SMAD2	Protein	TGFBR1	GeneID	BIND	T-beta-RI interacts with Smad2.
SMAD2	Protein	SKIL	GeneID	BIND	Smad2 interacts with SnoN. This interaction was modeled on a demonstrated interaction between SnoN from an unspecified source and human Smad2.
SMAD2	Protein	None	None	BIND	T-beta-R1/T-beta-R2 complex interacts with Smad2. This interaction was modeled on a demonstrated interaction between T-beta-R1/T-beta-R2 complex and Smad2 both from unspecified species.
SMAD2	Protein	SNW1	GeneID	BIND	SKIP interacts with Smad2. This interaction was modeled on a demonstrated interaction between human SKIP and Smad2 from an unspecified source.
SMAD2	Protein	BRCA1	GeneID	BIND	BRCA1 interacts with Smad2. This interaction was modeled on a demonstrated interaction between BRCA1 from human and Smad2 from an unspecified species.
SMAD2	Protein	SMAD3	GeneID	BIND	SMAD3 interacts with SMAD2.
SMAD2	Protein	SMURF2	GeneID	BIND	SMAD2 interacts with SMURF2.
SMAD2	Protein	LEMD3	GeneID	BIND	LEMD3 interacts with Smad2. This interaction was modelled on a demonstrated interaction between human LEMD3 and mouse Smad2.
SMAD2	Protein	SKI	GeneID	BIND	c-Ski interacts with Smad2. This interaction was modeled on a demonstrated interaction between Smad2 from an unspecified source and human c-Ski.
SMAD2	Protein	None	None	BIND	T-beta-R1/T-beta-R2 complex phosphorylates Smad2. This interaction was modeled on a demonstrated interaction between mouse T-beta-R1/T-beta-R2 complex and Smad2 from an unspecified species.
SMAD2	Protein	PML	GeneID	BIND	cPML interacts with Smad2.
SMAD2	Protein	E1A	GeneID	BIND	E1A interacts with Smad2. This interaction was modeled on a demonstrated interaction between E1A from an unspecified adenovirus and Smad2 from an unspecified source.
SMAD2	Protein	FOXH1	GeneID	BIND	FoxH1 interacts with Smad2. This interaction was modelled on a demonstrated interaction between FoxH1 from an unspecified species and Smad3 from an unspecified species.
SMAD2	Protein	CDK2	GeneID	BIND	CDK2 phosphorylates Smad2. This interaction was modelled on a demonstrated interaction between Smad2 from an unspecified species and human CDK2.
SMAD2	Protein	CDK4	GeneID	BIND	CDK4 phosphorylates Smad2. This interaction was modelled on a demonstrated interaction between Smad2 from an unspecified species and mouse CDK4.
SMAD2	Protein	ANAPC10	GeneID	BIND	Smad2 interacts with APC10.

StringDB

A	B	experiments	database	textmining	combined score	hadb	nhadb
SMAD2	SPATA17	0	0	0	164	1	1
SMAD2	CTNND1	0	0	220	238	1	1
SMAD2	RHOJ	128	0	108	206	1	1
SMAD2	SLC25A6	131	0	0	165	1	1
SMAD2	TTC4	0	0	734	738	1	1
SMAD2	TRIP12	0	0	45	233	1	1
SMAD2	SIRT2	0	0	168	417	1	2
SMAD2	ZFX	0	0	123	187	1	1
SMAD2	SLC4A7	0	0	0	229	1	1
SMAD2	WNT11	0	0	348	363	1	1
SMAD2	BIVM-ERCC5	0	0	0	177	1	1
SMAD2	ESRRA	0	0	107	155	1	1
SMAD2	SDHB	0	0	217	217	1	1
SMAD2	UBE2D3	0	900	66	906	1	1
SMAD2	RECK	0	0	181	188	1	1
SMAD2	DGCR8	0	0	241	259	1	1
SMAD2	CREBBP	872	900	693	997	1	1
SMAD2	GDF9	0	0	609	664	1	1
SMAD2	DHX9	0	0	82	161	1	1
SMAD2	WWP1	486	0	414	747	1	1
SMAD2	RAPGEF3	0	0	138	160	1	1
SMAD2	NOX3	0	0	135	154	1	1
SMAD2	APC	0	0	294	405	1	1
SMAD2	CREB1	0	0	401	447	1	2
SMAD2	USP9X	270	0	284	500	1	1
SMAD2	FGF14	0	0	49	308	1	1
SMAD2	WWC1	0	0	156	273	1	1
SMAD2	FGFR2	0	0	320	378	1	1
SMAD2	PML	270	900	195	938	1	2
SMAD2	DUSP5	0	0	91	166	1	1
SMAD2	GREM1	0	0	459	471	1	1
SMAD2	GAPDH	0	0	686	723	1	2
SMAD2	HAMP	0	0	243	242	1	1
SMAD2	TCF7L2	0	0	279	515	1	1
SMAD2	CRIM1	0	0	142	181	1	1
SMAD2	MAP2K7	0	0	468	482	1	1
SMAD2	CX3CL1	0	0	181	181	1	1
SMAD2	HIST4H4	0	0	233	232	1	1
SMAD2	ABL1	0	0	324	370	1	1
SMAD2	DACT1	0	0	144	169	1	1
SMAD2	BUB1	0	0	161	161	1	1
SMAD2	GSTM3	0	0	0	242	1	1
SMAD2	GNRHR	0	0	135	168	1	1
SMAD2	IGF2BP2	0	0	107	259	1	1
SMAD2	PTPN14	0	0	134	152	1	1
SMAD2	ELF5	0	0	173	183	1	1
SMAD2	WIF1	0	0	234	250	1	1
SMAD2	ZGLP1	0	0	0	159	1	1
SMAD2	ZIC1	0	0	155	183	1	1
SMAD2	STAT4	0	0	181	320	1	1
SMAD2	ZAP70	0	0	125	213	1	1
SMAD2	MMP20	0	0	0	362	1	1
SMAD2	HOXB9	0	0	145	218	1	1
SMAD2	NFKB1	0	0	232	294	1	2
SMAD2	KLF6	0	0	260	353	1	1
SMAD2	MFAP2	0	0	171	171	1	1
SMAD2	RORA	0	0	171	171	1	1
SMAD2	CARM1	0	0	82	160	1	2
SMAD2	RELA	0	0	321	322	1	2
SMAD2	HRAS	0	0	519	575	1	2
SMAD2	MYF5	0	0	294	379	1	1
SMAD2	CTNNB1	695	0	988	997	1	2
SMAD2	MSH6	0	0	261	261	1	1
SMAD2	EGR1	0	0	376	440	1	2
SMAD2	VENTX	0	0	85	245	1	1
SMAD2	APP	0	0	202	219	1	2
SMAD2	MFN2	131	0	74	265	1	2
SMAD2	LRG1	0	0	134	185	1	1
SMAD2	DDR2	0	0	203	203	1	1
SMAD2	WNT2B	0	0	268	440	1	1
SMAD2	NEO1	0	0	134	183	1	1
SMAD2	TGFBRAP1	213	900	326	942	1	1
SMAD2	MTSS1	0	0	134	152	1	1
SMAD2	BAZ1A	130	0	0	220	1	1
SMAD2	KLC3	0	0	830	833	1	1
SMAD2	WWC2	0	0	0	174	1	1
SMAD2	NEDD4	270	0	321	600	1	2
SMAD2	POSTN	0	0	460	463	1	1
SMAD2	FZD4	0	0	162	209	1	1
SMAD2	ISL1	0	0	186	215	1	1
SMAD2	BAG3	0	0	54	186	1	2
SMAD2	BMP15	0	0	424	519	1	1
SMAD2	BTG4	0	0	0	159	1	1
SMAD2	RAB5A	0	0	216	302	1	2
SMAD2	SGCD	0	0	90	168	1	1
SMAD2	CXCL8	0	0	425	432	1	2
SMAD2	LEFTY1	0	0	505	674	1	1
SMAD2	DLX4	270	0	89	318	1	1
SMAD2	GOLT1A	0	0	0	231	1	1
SMAD2	GBX2	0	0	123	193	1	1
SMAD2	IL6R	0	0	250	251	1	1
SMAD2	FSHB	0	0	163	246	1	1
SMAD2	PAX2	0	0	193	246	1	1
SMAD2	KLK3	0	0	170	182	1	1
SMAD2	MED6	270	0	0	270	1	1
SMAD2	WNT7A	0	0	334	349	1	1
SMAD2	UBE2G1	0	0	77	201	1	1
SMAD2	SMN1	0	0	372	406	1	1
SMAD2	ACAN	0	0	466	502	1	1
SMAD2	ETS2	0	0	242	322	1	1
SMAD2	PPP4C	0	0	74	206	1	1
SMAD2	MAP3K2	0	0	212	212	1	1
SMAD2	IGFBP7	0	0	188	188	1	1
SMAD2	TBL1XR1	0	0	95	178	1	1
SMAD2	CTRL	0	0	235	286	1	2
SMAD2	SOCS5	0	0	154	175	1	1
SMAD2	STAT1	0	0	452	486	1	2
SMAD2	PLEK	0	0	150	169	1	1
SMAD2	HFE2	0	0	158	164	1	1
SMAD2	OCLN	0	0	391	414	1	1
SMAD2	NPHS1	0	0	294	360	1	1
SMAD2	GZMB	0	0	213	225	1	1
SMAD2	CYR61	0	0	284	307	1	1
SMAD2	CXCR4	0	0	401	410	1	2
SMAD2	HIST1H4F	0	0	233	232	1	1
SMAD2	RRAS	0	0	138	199	1	1
SMAD2	NRP2	0	0	155	155	1	1
SMAD2	ARAF	0	0	125	210	1	1
SMAD2	MMP1	0	0	393	444	1	1
SMAD2	KLF17	0	0	194	215	1	1
SMAD2	TRIM59	0	0	134	161	1	1
SMAD2	MTOR	0	0	470	479	1	2
SMAD2	SUV420H1	0	0	65	164	1	1
SMAD2	PSMC6	0	0	202	248	1	1
SMAD2	JARID2	0	0	231	230	1	1
SMAD2	CD163	0	0	161	167	1	1
SMAD2	E2F2	0	0	202	215	1	1
SMAD2	MED15	270	900	681	977	1	1
SMAD2	TIMP4	0	0	213	213	1	1
SMAD2	ADAMTS1	0	0	162	205	1	1
SMAD2	RAF1	0	0	260	310	1	2
SMAD2	HOXC13	0	0	95	154	1	1
SMAD2	IRAK1	0	0	247	317	1	1
SMAD2	NCOR2	0	600	155	660	1	1
SMAD2	RREB1	0	0	99	166	1	1
SMAD2	RBL1	213	600	442	813	1	1
SMAD2	WNT4	0	0	325	381	1	1
SMAD2	NUP153	213	900	433	951	1	1
SMAD2	KPNA3	0	0	0	193	1	1
SMAD2	MAP3K7	0	0	517	561	1	2
SMAD2	HDAC2	117	900	433	948	1	1
SMAD2	TNFRSF11B	0	0	260	260	1	1
SMAD2	LAMA4	0	0	107	151	1	1
SMAD2	PAEP	0	0	466	465	1	1
SMAD2	EDA	0	0	290	304	1	1
SMAD2	TGM2	65	0	260	294	1	2
SMAD2	DCN	0	0	500	517	1	2
SMAD2	HOXA13	213	0	75	290	1	1
SMAD2	HECTD2	0	0	0	192	1	1
SMAD2	MDM2	0	0	392	414	1	2
SMAD2	LCN2	0	0	155	154	1	1
SMAD2	TP53	878	0	989	998	1	2
SMAD2	FLNB	0	0	453	468	1	1
SMAD2	AMHR2	0	0	390	444	1	1
SMAD2	LHX1	0	0	242	255	1	1
SMAD2	SLC2A1	0	0	161	183	1	2
SMAD2	HOXB4	0	0	100	157	1	1
SMAD2	FGFR3	0	0	234	300	1	1
SMAD2	MAP3K13	0	0	92	183	1	1
SMAD2	EGFR	0	0	560	582	1	2
SMAD2	CFLAR	0	0	208	236	1	2
SMAD2	ITGA5	0	0	264	297	1	1
SMAD2	PCSK5	0	0	94	227	1	1
SMAD2	SOX4	0	0	341	360	1	1
SMAD2	MUC5AC	0	0	166	262	1	1
SMAD2	MYH6	0	0	294	294	1	1
SMAD2	SERPINH1	0	0	294	320	1	1
SMAD2	KRT5	0	0	235	235	1	1
SMAD2	MMP15	0	0	57	437	1	1
SMAD2	UBR5	70	0	72	243	1	1
SMAD2	SEMA3B	0	0	170	169	1	1
SMAD2	GCAT	0	0	0	179	1	1
SMAD2	HBEGF	0	0	266	266	1	1
SMAD2	ITGB8	0	0	270	285	1	1
SMAD2	WNK1	0	0	433	441	1	1
SMAD2	GDNF	0	0	194	216	1	2
SMAD2	JAK2	0	0	324	378	1	2
SMAD2	SEMA3C	0	0	167	167	1	1
SMAD2	MTCH1	131	0	0	163	1	1
SMAD2	PTX3	0	0	167	167	1	1
SMAD2	CDH2	0	0	681	691	1	1
SMAD2	HDAC6	0	0	202	257	1	2
SMAD2	APAF1	0	0	172	193	1	2
SMAD2	RNF111	675	600	517	935	1	1
SMAD2	CLU	0	0	180	179	1	2
SMAD2	SEMA3D	0	0	157	176	1	1
SMAD2	MELK	0	0	48	546	1	1
SMAD2	HUWE1	130	0	112	306	1	1
SMAD2	BRD4	0	0	194	265	1	2
SMAD2	SFTPC	0	0	232	231	1	1
SMAD2	PPARD	0	0	69	153	1	1
SMAD2	CDH3	0	0	212	309	1	1
SMAD2	KLF10	0	0	414	465	1	1
SMAD2	NR4A1	0	0	194	194	1	2
SMAD2	CHST11	0	0	218	218	1	1
SMAD2	IBSP	0	0	210	306	1	1
SMAD2	VASN	0	0	181	195	1	1
SMAD2	RICTOR	0	0	234	238	1	2
SMAD2	ADORA1	0	0	90	198	1	1
SMAD2	PIK3R3	0	0	103	159	1	1
SMAD2	DVL1	270	0	275	565	1	1
SMAD2	TBX5	0	0	261	287	1	1
SMAD2	GNAQ	0	0	150	172	1	1
SMAD2	USP15	675	600	464	926	1	1
SMAD2	WWTR1	0	800	898	982	1	1
SMAD2	CBX4	0	0	74	175	1	1
SMAD2	TOP1	63	0	134	153	1	1
SMAD2	HNF4G	0	0	0	191	1	1
SMAD2	ACP5	0	0	246	245	1	1
SMAD2	IL2RA	0	0	162	370	1	1
SMAD2	IL15	0	0	233	232	1	1
SMAD2	FOXN3	0	0	82	155	1	1
SMAD2	ITGAE	0	0	230	229	1	1
SMAD2	CLOCK	0	0	109	164	1	2
SMAD2	WNT5A	0	0	423	470	1	2
SMAD2	ILK	0	0	459	479	1	1
SMAD2	NR0B2	0	0	453	469	1	1
SMAD2	IFNA1	0	0	206	206	1	1
SMAD2	SOX11	0	0	136	162	1	1
SMAD2	APC2	0	0	0	192	1	1
SMAD2	TRIM33	874	600	989	999	1	1
SMAD2	ADAM10	0	0	194	293	1	1
SMAD2	PPARGC1A	0	0	296	296	1	2
SMAD2	OGN	0	0	143	168	1	1
SMAD2	TDGF1	0	900	602	983	1	1
SMAD2	MYL9	0	0	166	241	1	1
SMAD2	NKX6-1	0	0	137	191	1	1
SMAD2	SND1	0	0	148	155	1	1
SMAD2	FRS2	0	0	230	229	1	1
SMAD2	AREG	0	0	259	258	1	1
SMAD2	KRT4	0	0	158	157	1	1
SMAD2	STK11	0	0	290	307	1	2
SMAD2	PAX9	0	0	141	273	1	1
SMAD2	PITX1	0	0	122	154	1	1
SMAD2	BRCA1	213	0	310	433	1	2
SMAD2	PDGFB	0	0	391	412	1	2
SMAD2	FZD2	0	0	158	206	1	1
SMAD2	CDKN2D	0	0	108	154	1	1
SMAD2	OPA1	257	0	90	322	1	2
SMAD2	FUT4	0	0	204	204	1	1
SMAD2	ST13	70	0	142	167	1	2
SMAD2	AQP1	0	0	134	159	1	1
SMAD2	TCF3	0	0	238	269	1	1
SMAD2	DLX2	0	0	194	213	1	1
SMAD2	LRP5	0	0	376	392	1	1
SMAD2	TNFRSF12A	0	0	155	154	1	1
SMAD2	FLNA	0	0	694	703	1	1
SMAD2	TTN	0	0	180	200	1	1
SMAD2	LEMD3	885	0	926	993	1	1
SMAD2	TMEM45A	0	0	0	151	1	1
SMAD2	INHBA	0	900	459	951	1	1
SMAD2	CCNT1	0	900	53	904	1	1
SMAD2	ACTA1	0	0	322	465	1	1
SMAD2	VPS39	0	0	397	400	1	1
SMAD2	DUSP4	0	0	113	286	1	1
SMAD2	SAMD1	0	0	218	226	1	1
SMAD2	PTK2	0	0	570	579	1	2
SMAD2	ZNF217	0	0	127	166	1	1
SMAD2	MAPK8	213	0	468	584	1	2
SMAD2	BMP1	0	0	401	443	1	1
SMAD2	FRZB	0	0	241	275	1	1
SMAD2	CFC1B	0	0	0	174	1	1
SMAD2	BRAF	0	0	136	224	1	2
SMAD2	CTDSPL	270	900	45	931	1	1
SMAD2	FGF18	0	0	163	342	1	1
SMAD2	MUT	0	0	283	360	1	1
SMAD2	MAP2K4	0	0	295	314	1	1
SMAD2	MMP16	0	0	142	385	1	1
SMAD2	PSMD11	130	0	94	178	1	1
SMAD2	HBZ	0	0	921	923	1	1
SMAD2	EFEMP2	0	0	349	363	1	1
SMAD2	COL4A1	0	0	294	381	1	1
SMAD2	FBXO11	0	0	427	439	1	1
SMAD2	ABL2	0	0	107	168	1	1
SMAD2	CHKA	0	0	171	171	1	1
SMAD2	FSTL3	0	0	420	421	1	1
SMAD2	CCR1	0	0	127	236	1	1
SMAD2	HSPA4	257	0	442	568	1	1
SMAD2	ETV5	0	0	112	161	1	1
SMAD2	GATA4	0	0	413	551	1	2
SMAD2	PIK3R1	0	0	243	242	1	1
SMAD2	DICER1	0	0	525	574	1	1
SMAD2	EPB41L5	257	0	95	342	1	1
SMAD2	PLAUR	0	0	261	261	1	1
SMAD2	HSP90B1	0	0	89	212	1	1
SMAD2	HSPB3	0	0	269	269	1	1
SMAD2	XPO5	0	0	218	218	1	1
SMAD2	TRPC6	0	0	203	208	1	1
SMAD2	CYP2E1	0	0	170	183	1	2
SMAD2	PDCD4	0	0	603	608	1	2
SMAD2	COL4A4	0	0	66	171	1	1
SMAD2	MESP1	0	0	156	155	1	1
SMAD2	CCR2	0	0	244	265	1	2
SMAD2	PPARA	0	0	366	398	1	2
SMAD2	TEK	0	0	327	341	1	1
SMAD2	KIAA1328	0	0	0	153	1	1
SMAD2	VCAN	0	0	372	372	1	1
SMAD2	FLCN	0	0	66	159	1	1
SMAD2	TRAF6	0	0	927	930	1	2
SMAD2	GADD45B	0	0	277	304	1	1
SMAD2	CYCS	0	0	269	269	1	2
SMAD2	PPM1L	0	0	0	230	1	1
SMAD2	CXCL11	0	0	421	420	1	1
SMAD2	PDP1	0	0	72	286	1	1
SMAD2	RAC3	0	0	92	179	1	2
SMAD2	IGFBP1	0	0	104	177	1	1
SMAD2	FBLN5	0	0	207	224	1	1
SMAD2	PLAU	0	0	321	336	1	1
SMAD2	ZNF32	0	0	167	188	1	1
SMAD2	HNF1A	0	0	182	191	1	1
SMAD2	EGF	0	0	612	664	1	2
SMAD2	SP4	0	0	0	159	1	1
SMAD2	BMP2	0	0	611	794	1	1
SMAD2	CDK5	0	0	154	172	1	2
SMAD2	PRMT6	0	0	0	157	1	1
SMAD2	EP300	757	900	971	999	1	2
SMAD2	NUMB	0	0	171	190	1	1
SMAD2	PDGFRB	0	0	342	366	1	2
SMAD2	LEF1	486	0	556	832	1	1
SMAD2	ELMO1	0	0	0	168	1	1
SMAD2	PRMT3	0	0	0	158	1	1
SMAD2	WNT9B	0	0	266	354	1	1
SMAD2	IL4	0	0	425	424	1	1
SMAD2	BIRC3	0	0	125	177	1	1
SMAD2	DOK1	0	0	47	213	1	1
SMAD2	IL17F	0	0	218	218	1	1
SMAD2	SMAD3	897	900	990	990	1	2
SMAD2	SOX15	0	0	95	156	1	1
SMAD2	SPARC	0	0	323	332	1	2
SMAD2	ONECUT1	0	0	167	199	1	1
SMAD2	KLK10	0	0	143	156	1	1
SMAD2	HNF1B	0	0	202	211	1	1
SMAD2	ROCK1	70	0	349	426	1	2
SMAD2	SNAI2	0	0	681	736	1	1
SMAD2	EIF4A1	0	0	81	200	1	1
SMAD2	SFRP5	0	0	140	285	1	1
SMAD2	CD68	0	0	310	325	1	2
SMAD2	UTRN	0	0	68	177	1	1
SMAD2	ALB	0	0	566	660	1	2
SMAD2	CCL2	0	0	463	468	1	2
SMAD2	DUSP9	0	0	108	195	1	1
SMAD2	RAP2A	0	0	91	156	1	1
SMAD2	GTF2IRD1	270	0	154	414	1	1
SMAD2	DUSP7	0	0	52	273	1	1
SMAD2	THBS4	0	0	155	154	1	1
SMAD2	XPO4	0	0	180	296	1	1
SMAD2	ELAVL1	42	0	165	185	1	2
SMAD2	CSNK1D	474	0	74	528	1	1
SMAD2	CASP7	0	0	242	259	1	1
SMAD2	CUL1	0	800	203	837	1	1
SMAD2	EREG	0	0	193	210	1	1
SMAD2	LOXL2	0	0	283	282	1	1
SMAD2	GLMN	0	0	60	157	1	1
SMAD2	H3F3B	0	0	67	165	1	1
SMAD2	MAP3K11	0	0	113	174	1	1
SMAD2	GATA1	0	0	245	339	1	1
SMAD2	NODAL	0	900	520	960	1	1
SMAD2	MAF	0	0	245	259	1	1
SMAD2	ZYX	0	0	155	162	1	1
SMAD2	ACTR1B	0	0	95	150	1	1
SMAD2	CRYGC	0	0	212	212	1	1
SMAD2	ACVR2B	270	900	738	987	1	1
SMAD2	MAGI3	0	0	0	199	1	1
SMAD2	CHSY1	0	0	205	205	1	1
SMAD2	SKOR2	213	0	833	873	1	1
SMAD2	PAX6	0	0	324	332	1	1
SMAD2	WNT1	0	0	419	548	1	2
SMAD2	ROCK2	0	0	206	327	1	1
SMAD2	ALK	0	0	520	628	1	2
SMAD2	ACTC1	0	0	142	426	1	1
SMAD2	AGER	0	0	193	193	1	2
SMAD2	DUSP8	0	0	48	252	1	1
SMAD2	WNT16	0	0	269	286	1	1
SMAD2	SIRT6	0	0	201	233	1	2
SMAD2	ALCAM	0	0	193	193	1	1
SMAD2	PDGFRA	0	0	284	298	1	1
SMAD2	FNDC5	0	0	153	152	1	1
SMAD2	PRKCZ	0	0	182	247	1	1
SMAD2	IGF2BP1	0	0	90	165	1	1
SMAD2	CDH1	0	0	740	812	1	2
SMAD2	SOX8	0	0	89	171	1	1
SMAD2	AR	0	0	372	411	1	2
SMAD2	CDCA7	0	0	46	170	1	1
SMAD2	GNRH1	0	0	212	261	1	1
SMAD2	CDKN1A	0	0	517	526	1	2
SMAD2	SPP1	0	0	466	478	1	2
SMAD2	TIMP1	0	0	595	595	1	1
SMAD2	HOXD3	0	0	88	169	1	1
SMAD2	BAX	0	0	211	211	1	2
SMAD2	GPR29	0	0	144	158	1	1
SMAD2	TNNI3	0	0	108	222	1	1
SMAD2	CITED2	270	0	441	574	1	1
SMAD2	AURKA	0	0	181	198	1	2
SMAD2	DUSP16	0	0	0	204	1	1
SMAD2	GDF3	0	0	341	517	1	1
SMAD2	MIXL1	0	0	476	529	1	1
SMAD2	PRG4	0	0	204	217	1	1
SMAD2	HOXD10	0	0	115	173	1	1
SMAD2	PTPRC	0	0	417	452	1	1
SMAD2	SOST	0	0	293	293	1	1
SMAD2	WISP2	0	0	219	219	1	1
SMAD2	SF3B2	63	0	0	200	1	1
SMAD2	KPNA5	0	0	0	202	1	1
SMAD2	CKM	0	0	74	172	1	1
SMAD2	ELAC2	270	0	822	864	1	1
SMAD2	ITGAV	0	0	294	302	1	1
SMAD2	ICAM1	0	0	370	384	1	2
SMAD2	CCNB2	0	0	123	212	1	1
SMAD2	SAR1A	0	900	74	913	1	1
SMAD2	FOXA3	0	0	126	199	1	1
SMAD2	SOX9	270	0	780	847	1	1
SMAD2	PRRX1	0	0	155	286	1	1
SMAD2	S100A11	0	0	164	163	1	1
SMAD2	E2F7	0	0	169	195	1	1
SMAD2	IL21	0	0	89	228	1	1
SMAD2	ZMYM2	0	0	0	199	1	1
SMAD2	HDAC4	107	0	352	427	1	2
SMAD2	HSP90AA1	0	0	293	516	1	2
SMAD2	POFUT1	0	0	74	181	1	1
SMAD2	CTBP1	0	900	218	920	1	1
SMAD2	SPG20	63	0	58	165	1	1
SMAD2	CRP	0	0	183	193	1	2
SMAD2	ATF2	0	0	172	318	1	1
SMAD2	TP73	213	0	112	321	1	2
SMAD2	PSEN1	0	0	164	163	1	2
SMAD2	DES	0	0	0	202	1	2
SMAD2	SOX2	0	600	518	835	1	2
SMAD2	CFC1	0	900	273	934	1	1
SMAD2	PRDM14	0	600	184	737	1	1
SMAD2	FGF1	0	0	320	319	1	1
SMAD2	HOXA5	0	0	103	160	1	1
SMAD2	SLA2	0	0	0	207	1	1
SMAD2	FUT8	0	0	247	263	1	1
SMAD2	SELL	0	0	195	209	1	1
SMAD2	MSN	0	0	165	165	1	1
SMAD2	SELP	0	0	134	209	1	1
SMAD2	SQSTM1	128	0	447	497	1	2
SMAD2	BNIP3	0	0	160	159	1	2
SMAD2	TFDP1	0	600	77	618	1	1
SMAD2	JUNB	0	900	216	921	1	1
SMAD2	NIPBL	0	0	120	282	1	1
SMAD2	ING3	0	0	451	458	1	1
SMAD2	THY1	0	0	381	388	1	1
SMAD2	CUL4A	117	0	66	156	1	1
SMAD2	KLF15	0	0	185	221	1	1
SMAD2	MAPK3	213	900	681	977	1	2
SMAD2	GTF2I	270	0	695	777	1	1
SMAD2	RANBP9	130	0	0	153	1	1
SMAD2	MMP9	0	0	651	695	1	2
SMAD2	DNTT	0	0	283	291	1	1
SMAD2	GRHL2	0	0	156	155	1	1
SMAD2	GPC4	0	0	138	305	1	1
SMAD2	FZD10	0	0	113	170	1	1
SMAD2	CCNA2	0	0	310	372	1	1
SMAD2	EIF4ENIF1	0	0	0	181	1	1
SMAD2	ERBB4	0	0	280	316	1	1
SMAD2	SIX4	0	0	57	185	1	1
SMAD2	COL18A1	0	0	143	161	1	1
SMAD2	JAK3	0	0	148	221	1	1
SMAD2	HMG20B	0	0	57	202	1	1
SMAD2	PIK3CG	0	0	203	246	1	1
SMAD2	SERPINB2	0	0	92	199	1	1
SMAD2	NPPB	0	0	202	202	1	1
SMAD2	CDH17	0	0	414	423	1	1
SMAD2	TBX20	0	0	103	225	1	1
SMAD2	ENSG00000173366	0	0	164	178	1	1
SMAD2	CYP19A1	0	0	216	233	1	2
SMAD2	PARD3B	0	0	90	156	1	1
SMAD2	JUN	684	0	738	921	1	2
SMAD2	DAPK1	0	0	170	188	1	2
SMAD2	FZD1	0	0	230	274	1	1
SMAD2	TYK2	0	0	141	221	1	1
SMAD2	MKX	0	0	186	232	1	1
SMAD2	CTDSP2	0	900	87	916	1	1
SMAD2	GRB2	0	0	377	404	1	1
SMAD2	MAX	0	900	49	904	1	2
SMAD2	FYN	0	0	203	324	1	1
SMAD2	DOCK9	257	0	54	267	1	1
SMAD2	JAG1	0	0	425	506	1	1
SMAD2	FST	0	0	636	672	1	1
SMAD2	BMI1	0	0	310	325	1	1
SMAD2	ARNT	0	0	193	214	1	2
SMAD2	SOD1	63	0	173	191	1	2
SMAD2	LTA	0	0	113	265	1	1
SMAD2	KPNA2	0	900	75	911	1	1
SMAD2	TBL1X	0	0	209	248	1	1
SMAD2	CDC25C	0	0	96	172	1	2
SMAD2	COMP	0	0	207	207	1	1
SMAD2	CITED1	0	900	276	924	1	1
SMAD2	SPTBN1	270	0	92	443	1	1
SMAD2	SULF1	0	0	138	191	1	1
SMAD2	CENPE	0	0	62	171	1	1
SMAD2	SOX17	0	0	456	491	1	1
SMAD2	FGF6	0	0	91	435	1	1
SMAD2	MFN1	0	0	71	267	1	2
SMAD2	PUM2	0	0	0	177	1	1
SMAD2	BMP6	0	0	556	664	1	1
SMAD2	RING1	0	0	137	164	1	1
SMAD2	IRS2	0	0	160	181	1	1
SMAD2	UCHL1	0	0	139	163	1	2
SMAD2	BTG1	0	0	0	159	1	1
SMAD2	SMAD1	610	800	608	923	1	2
SMAD2	NEDD9	270	0	210	458	1	1
SMAD2	COL3A1	0	0	503	613	1	1
SMAD2	KRT8	0	0	322	321	1	1
SMAD2	ID4	0	0	260	265	1	1
SMAD2	NFATC3	0	0	163	177	1	1
SMAD2	RUNX3	270	0	335	520	1	1
SMAD2	IRF6	0	0	248	248	1	1
SMAD2	NCOA3	486	0	265	614	1	1
SMAD2	ENSG00000270024	0	0	134	175	1	1
SMAD2	TH	0	0	107	167	1	2
SMAD2	ACVR1B	270	900	947	997	1	1
SMAD2	YES1	0	0	95	232	1	1
SMAD2	FOXF1	0	0	241	329	1	1
SMAD2	FOXJ1	0	0	120	179	1	1
SMAD2	GJA5	0	0	141	177	1	1
SMAD2	MED24	270	0	60	284	1	1
SMAD2	NGF	0	0	262	262	1	2
SMAD2	CD34	0	0	391	411	1	2
SMAD2	CREM	0	0	94	174	1	1
SMAD2	FBN1	0	0	556	582	1	1
SMAD2	STC2	0	0	217	354	1	1
SMAD2	SQRDL	257	0	0	256	1	1
SMAD2	TGFBI	0	0	405	424	1	1
SMAD2	NR5A2	0	0	155	154	1	1
SMAD2	FOXQ1	0	0	144	202	1	1
SMAD2	ZNF521	0	0	140	179	1	1
SMAD2	ZNF652	0	0	147	221	1	1
SMAD2	BSCL2	0	0	0	155	1	1
SMAD2	KRT18	0	0	285	284	1	1
SMAD2	PMS2	0	0	204	204	1	1
SMAD2	CYLD	0	0	206	309	1	1
SMAD2	EIF4EBP1	0	0	310	309	1	2
SMAD2	HSP90AB1	0	0	66	406	1	2
SMAD2	EYA2	0	0	70	192	1	1
SMAD2	PEX6	0	0	48	187	1	1
SMAD2	FOXO4	0	900	430	945	1	1
SMAD2	AXL	0	0	206	260	1	2
SMAD2	RBBP5	270	0	75	342	1	1
SMAD2	GJA1	0	0	369	381	1	1
SMAD2	BCL6	0	0	257	277	1	1
SMAD2	SOSTDC1	0	0	193	198	1	1
SMAD2	FOXH1	885	900	989	999	1	1
SMAD2	KIAA1804	0	0	120	180	1	1
SMAD2	PHGDH	0	0	167	180	1	1
SMAD2	GDF1	0	0	373	453	1	1
SMAD2	PDE5A	0	0	170	171	1	1
SMAD2	GPT	0	0	281	296	1	1
SMAD2	BMP8B	0	0	241	339	1	1
SMAD2	COL4A3	0	0	125	204	1	1
SMAD2	PSMD5	0	0	193	210	1	1
SMAD2	MTMR4	280	600	154	745	1	1
SMAD2	KMT2D	0	0	142	169	1	1
SMAD2	DROSHA	0	0	950	959	1	1
SMAD2	NOX4	0	0	635	635	1	2
SMAD2	E2F4	213	600	719	906	1	1
SMAD2	DUOX1	0	0	219	219	1	1
SMAD2	SKI	897	900	193	996	1	1
SMAD2	TGIF1	678	900	941	998	1	1
SMAD2	CLDN1	0	0	141	173	1	1
SMAD2	TGIF2	0	800	294	862	1	1
SMAD2	SCN5A	0	0	108	374	1	1
SMAD2	GDF7	0	0	270	364	1	1
SMAD2	CDK8	270	900	340	959	1	1
SMAD2	NTRK2	0	0	134	212	1	1
SMAD2	COL4A2	0	0	134	258	1	1
SMAD2	MZF1	0	0	113	204	1	1
SMAD2	VCAM1	0	0	325	330	1	1
SMAD2	INPP5D	0	0	150	151	1	1
SMAD2	MXD1	0	0	150	185	1	1
SMAD2	FAS	0	0	140	159	1	2
SMAD2	SUMO1	0	0	143	181	1	1
SMAD2	FBN2	70	0	270	334	1	1
SMAD2	DYM	0	0	94	187	1	1
SMAD2	CSF2	0	0	309	309	1	1
SMAD2	HIST1H4C	0	0	233	248	1	1
SMAD2	CTDP1	0	0	82	166	1	1
SMAD2	CPT1A	0	0	76	156	1	1
SMAD2	CNN1	0	0	268	274	1	1
SMAD2	PRKCD	0	0	267	267	1	2
SMAD2	USP7	270	0	182	377	1	1
SMAD2	MMP10	0	0	229	372	1	1
SMAD2	TGFB1	0	900	739	985	1	2
SMAD2	KRT19	0	0	330	338	1	1
SMAD2	STAT5B	0	0	392	442	1	1
SMAD2	LUM	0	0	287	304	1	1
SMAD2	SCGB1A1	0	0	141	159	1	1
SMAD2	ARID3B	0	0	0	165	1	1
SMAD2	KLF8	0	0	170	211	1	1
SMAD2	DDX20	0	0	45	184	1	1
SMAD2	CLDN7	0	0	162	162	1	1
SMAD2	KDR	0	0	427	447	1	2
SMAD2	SKP1	0	800	194	835	1	2
SMAD2	CLDN4	0	0	181	191	1	1
SMAD2	PRMT5	282	0	123	343	1	1
SMAD2	AGTR2	0	0	218	231	1	1
SMAD2	NKX3-1	0	0	103	160	1	1
SMAD2	YY1	474	0	261	622	1	1
SMAD2	RAB11A	0	0	164	200	1	2
SMAD2	RAC2	0	0	178	246	1	1
SMAD2	SEMA3F	0	0	161	161	1	1
SMAD2	CORO2A	154	0	0	153	1	1
SMAD2	DYNLRB1	0	900	57	902	1	1
SMAD2	ASPN	0	0	150	208	1	1
SMAD2	TBK1	0	0	99	166	1	2
SMAD2	YTHDC2	0	0	0	187	1	1
SMAD2	FOXP3	0	0	517	828	1	2
SMAD2	HIST1H4D	0	0	233	232	1	1
SMAD2	METTL14	270	0	180	444	1	1
SMAD2	TP53INP1	0	0	152	167	1	2
SMAD2	SERPINB7	0	0	0	153	1	1
SMAD2	HNF4A	213	0	908	933	1	1
SMAD2	CXXC5	0	0	441	441	1	1
SMAD2	EID2	270	0	309	474	1	1
SMAD2	NAGLU	0	0	0	206	1	1
SMAD2	LPAR1	0	0	150	164	1	1
SMAD2	JDP2	0	0	75	460	1	1
SMAD2	SEMA4F	0	0	159	158	1	1
SMAD2	TLR3	0	0	184	198	1	2
SMAD2	CDKN3	0	0	289	301	1	1
SMAD2	TRIM28	270	0	444	590	1	2
SMAD2	SIN3B	0	900	0	909	1	1
SMAD2	CDC42	0	0	414	453	1	2
SMAD2	PODXL	0	0	153	152	1	1
SMAD2	DKK1	0	0	404	425	1	1
SMAD2	FOXO3	213	900	904	993	1	2
SMAD2	GATA5	0	0	248	413	1	1
SMAD2	SLC2A4	0	0	181	203	1	1
SMAD2	FMNL1	0	0	195	195	1	1
SMAD2	APOE	0	0	289	288	1	2
SMAD2	BMPER	0	0	253	345	1	1
SMAD2	TNFSF11	0	0	391	390	1	2
SMAD2	ACTG2	0	0	107	295	1	1
SMAD2	BGLAP	0	0	425	451	1	1
SMAD2	ITGA6	0	0	224	224	1	1
SMAD2	SEMA3A	0	0	217	217	1	1
SMAD2	JUND	0	0	181	242	1	1
SMAD2	NOS3	0	0	450	462	1	2
SMAD2	ACTA2	0	0	396	744	1	1
SMAD2	FSHR	0	0	157	175	1	1
SMAD2	CCND1	0	0	556	600	1	2
SMAD2	MEIS1	0	0	113	216	1	1
SMAD2	FLI1	0	0	90	182	1	1
SMAD2	LOXL1	0	0	181	181	1	1
SMAD2	PRKAA1	0	0	107	152	1	2
SMAD2	WNT9A	0	0	275	362	1	1
SMAD2	FGF5	0	0	267	394	1	1
SMAD2	CD19	0	0	171	171	1	1
SMAD2	UBE2I	0	0	161	193	1	1
SMAD2	PSPC1	257	0	82	290	1	1
SMAD2	IRAK2	94	0	92	201	1	1
SMAD2	NCF1	0	0	210	210	1	1
SMAD2	MYL2	0	0	194	218	1	1
SMAD2	ANXA2	0	0	181	181	1	1
SMAD2	SKIV2L2	0	0	0	158	1	1
SMAD2	SPNS3	0	0	0	157	1	1
SMAD2	NOX5	0	0	181	181	1	1
SMAD2	KLF1	0	0	138	172	1	1
SMAD2	RANBP3	270	0	440	646	1	1
SMAD2	HIST2H2BE	0	0	166	165	1	1
SMAD2	ETV6	0	0	95	191	1	1
SMAD2	PPP2CA	0	0	122	190	1	1
SMAD2	EIF4E	0	0	265	297	1	2
SMAD2	SPAM1	0	0	103	164	1	1
SMAD2	PRRX2	0	0	102	230	1	1
SMAD2	GPC6	0	0	134	301	1	1
SMAD2	KAT2B	675	900	260	976	1	1
SMAD2	OLIG2	0	0	146	165	1	1
SMAD2	HEY1	0	0	293	298	1	1
SMAD2	HIVEP1	0	0	306	591	1	1
SMAD2	SAV1	0	0	209	244	1	1
SMAD2	COL6A3	0	0	171	252	1	1
SMAD2	RUNX1	270	0	123	442	1	2
SMAD2	PTK2B	0	0	159	178	1	1
SMAD2	NKX2-5	0	900	337	939	1	1
SMAD2	UBB	0	600	0	655	1	1
SMAD2	IGSF1	0	0	170	246	1	1
SMAD2	PECAM1	0	0	504	526	1	1
SMAD2	CCNK	0	900	0	900	1	1
SMAD2	FSTL1	0	0	243	250	1	1
SMAD2	BMP5	0	0	381	528	1	1
SMAD2	ENSG00000264813	0	0	425	433	1	1
SMAD2	LRP6	0	0	308	326	1	1
SMAD2	TXN	0	0	173	185	1	1
SMAD2	FOXP4	0	0	0	187	1	1
SMAD2	NPHS2	0	0	150	177	1	2
SMAD2	SAP18	0	900	0	900	1	1
SMAD2	HAPLN1	0	0	137	218	1	1
SMAD2	CCNE1	0	0	203	319	1	1
SMAD2	SCX	0	0	358	425	1	1
SMAD2	MDK	0	0	86	414	1	1
SMAD2	HIST2H4B	0	0	233	232	1	1
SMAD2	MAP2K2	0	0	119	168	1	1
SMAD2	ALPL	0	0	241	261	1	1
SMAD2	RHEB	0	0	167	191	1	2
SMAD2	CDX4	0	0	107	170	1	1
SMAD2	KLF9	0	0	146	168	1	1
SMAD2	SLC16A8	0	0	270	270	1	1
SMAD2	SH2D2A	270	0	448	580	1	1
SMAD2	LDLR	0	0	194	194	1	2
SMAD2	COL7A1	0	0	207	285	1	1
SMAD2	GNB2L1	0	0	113	211	1	1
SMAD2	TRPS1	0	0	81	194	1	1
SMAD2	E2F8	0	0	150	174	1	1
SMAD2	POU2F1	0	0	95	164	1	1
SMAD2	CCNT2	0	900	0	902	1	1
SMAD2	ACVR2A	0	900	681	979	1	1
SMAD2	TSSK1B	0	0	193	193	1	1
SMAD2	IL23R	0	0	181	181	1	1
SMAD2	BRE	0	0	401	414	1	1
SMAD2	GPC1	0	900	270	928	1	1
SMAD2	HERC6	0	0	0	174	1	1
SMAD2	TMSB4X	0	0	159	158	1	1
SMAD2	NRIP1	0	0	95	157	1	1
SMAD2	VCL	0	0	310	344	1	1
SMAD2	GPC5	0	0	108	230	1	1
SMAD2	MMP7	0	0	325	483	1	1
SMAD2	ARNT2	0	0	61	164	1	1
SMAD2	DKK3	0	0	184	190	1	1
SMAD2	GPC2	0	0	103	209	1	1
SMAD2	UCP3	0	0	67	165	1	1
SMAD2	BDNF	0	0	219	219	1	2
SMAD2	CD44	0	0	517	535	1	2
SMAD2	ADAMTS4	0	0	204	218	1	1
SMAD2	IL7	0	0	202	202	1	1
SMAD2	PAFAH1B1	0	0	0	171	1	1
SMAD2	MYF6	0	0	162	276	1	1
SMAD2	SEMA4D	0	0	160	159	1	1
SMAD2	SIX1	0	0	436	454	1	1
SMAD2	LTBP4	0	0	433	445	1	1
SMAD2	MIPOL1	0	0	0	185	1	1
SMAD2	EYA1	0	0	0	197	1	1
SMAD2	YBX1	0	0	241	257	1	1
SMAD2	SMARCD1	0	0	58	225	1	1
SMAD2	EPHB6	63	0	70	153	1	1
SMAD2	ADAMTS9	0	0	82	169	1	1
SMAD2	NOV	0	0	211	211	1	1
SMAD2	EYA3	0	0	0	167	1	1
SMAD2	BTK	0	0	92	182	1	1
SMAD2	SOCS1	0	0	325	334	1	1
SMAD2	CCND3	0	0	171	207	1	1
SMAD2	NEDD4L	671	900	974	999	1	1
SMAD2	CSF1R	0	0	210	226	1	1
SMAD2	TNMD	0	0	358	358	1	1
SMAD2	ITGA3	0	0	160	171	1	2
SMAD2	IGF1	0	0	634	648	1	2
SMAD2	MAPK1	213	900	394	957	1	2
SMAD2	PPP2R1A	130	0	75	171	1	1
SMAD2	SDC4	0	0	245	244	1	1
SMAD2	EPHB4	0	0	134	227	1	1
SMAD2	GADD45A	0	0	207	264	1	1
SMAD2	ESRRB	0	0	262	283	1	1
SMAD2	SFRP4	0	0	167	204	1	1
SMAD2	PLEKHA4	270	0	0	277	1	1
SMAD2	FAM83G	257	0	112	312	1	1
SMAD2	RELB	270	0	233	416	1	2
SMAD2	FGF2	0	0	600	640	1	2
SMAD2	TNNT2	0	0	167	167	1	1
SMAD2	PTCH1	0	0	335	369	1	1
SMAD2	POTEI	0	0	0	155	1	1
SMAD2	AXIN2	0	0	369	415	1	1
SMAD2	SOS1	0	0	194	230	1	1
SMAD2	TNFAIP6	0	0	211	222	1	1
SMAD2	SPRY2	0	0	162	168	1	1
SMAD2	HIST1H4H	0	0	233	232	1	1
SMAD2	ENSG00000272980	0	0	144	158	1	1
SMAD2	SOX5	0	0	181	212	1	1
SMAD2	TMEM9	0	0	57	157	1	1
SMAD2	U2AF2	257	0	53	294	1	1
SMAD2	CD2AP	0	0	108	165	1	1
SMAD2	VWF	0	0	291	311	1	1
SMAD2	CD63	0	0	196	196	1	2
SMAD2	PCBP1	106	0	125	184	1	1
SMAD2	RALA	0	0	108	186	1	1
SMAD2	CASR	0	0	124	151	1	2
SMAD2	KDM5B	0	0	210	227	1	1
SMAD2	VTN	0	0	294	305	1	1
SMAD2	GPX1	0	0	96	152	1	1
SMAD2	CCR7	0	0	180	179	1	1
SMAD2	IKBKG	0	0	232	265	1	1
SMAD2	RARA	0	0	206	232	1	2
SMAD2	RCOR1	0	0	124	163	1	1
SMAD2	AKT3	0	0	150	300	1	2
SMAD2	THPO	0	0	95	236	1	1
SMAD2	SKIL	871	900	988	999	1	1
SMAD2	RPS6KA1	0	0	243	242	1	1
SMAD2	STMN1	0	0	125	185	1	1
SMAD2	SOD3	0	0	123	152	1	1
SMAD2	MAP3K12	0	0	95	186	1	1
SMAD2	TBX21	0	0	324	348	1	1
SMAD2	DACH1	0	0	142	181	1	1
SMAD2	KLF16	0	0	141	163	1	1
SMAD2	NCAM1	0	0	179	221	1	1
SMAD2	LATS1	0	0	323	355	1	1
SMAD2	MCAM	0	0	166	165	1	1
SMAD2	PIAS3	270	900	154	960	1	1
SMAD2	NFKBIB	0	0	84	155	1	1
SMAD2	SERPINB8	0	0	0	153	1	1
SMAD2	TMEFF1	0	0	310	429	1	1
SMAD2	ADAM17	0	0	284	300	1	1
SMAD2	ARID1A	270	0	216	421	1	1
SMAD2	S100A4	270	0	502	620	1	1
SMAD2	TGFBR1	870	900	986	999	1	1
SMAD2	SOCS6	0	0	160	172	1	1
SMAD2	CTHRC1	0	0	217	244	1	1
SMAD2	ADAM19	0	0	148	257	1	1
SMAD2	HSPB1	0	0	241	241	1	2
SMAD2	ENSG00000255819	0	0	218	231	1	1
SMAD2	GLI1	270	0	413	573	1	2
SMAD2	CMA1	0	0	185	197	1	1
SMAD2	RBBP9	0	0	170	169	1	1
SMAD2	DYRK1A	270	0	81	325	1	1
SMAD2	WISP3	0	0	167	167	1	1
SMAD2	HSPB2	0	0	242	242	1	1
SMAD2	TP63	486	0	156	824	1	2
SMAD2	SP3	0	0	141	218	1	1
SMAD2	HIPK2	270	0	193	422	1	2
SMAD2	SOX6	0	0	180	223	1	1
SMAD2	STAT2	0	0	122	201	1	1
SMAD2	XBP1	0	0	194	194	1	2
SMAD2	PTPN1	0	0	166	183	1	1
SMAD2	MPL	0	0	61	264	1	1
SMAD2	PUM1	0	0	0	185	1	1
SMAD2	PTPRZ1	0	0	120	171	1	1
SMAD2	SAMD3	0	0	426	556	1	1
SMAD2	GATA6	0	0	513	580	1	1
SMAD2	MAP2K6	0	0	216	265	1	1
SMAD2	ATG5	0	0	248	264	1	2
SMAD2	HTATIP2	0	0	57	157	1	1
SMAD2	MT-ND1	0	0	0	188	1	1
SMAD2	WNT3A	0	0	470	517	1	2
SMAD2	CAMK2G	270	0	0	283	1	1
SMAD2	YIPF1	0	0	247	246	1	1
SMAD2	ITGB3	0	0	288	313	1	1
SMAD2	KCP	0	0	242	335	1	1
SMAD2	MAP3K5	0	0	244	243	1	1
SMAD2	ZNF510	170	0	0	191	1	1
SMAD2	GATA2	0	0	243	374	1	1
SMAD2	ITGAM	0	0	332	332	1	1
SMAD2	T	0	0	142	616	1	1
SMAD2	RNH1	0	0	181	181	1	1
SMAD2	EYA4	0	0	45	294	1	1
SMAD2	CTSK	0	0	242	241	1	2
SMAD2	LYN	0	0	126	186	1	1
SMAD2	COPS5	70	0	208	231	1	1
SMAD2	RBBP4	0	900	95	910	1	1
SMAD2	RAC1	0	0	156	188	1	2
SMAD2	DUOX2	0	0	180	179	1	1
SMAD2	HMGB1	0	0	260	278	1	2
SMAD2	CTSB	0	0	166	165	1	2
SMAD2	SPI1	0	0	327	433	1	1
SMAD2	NOX1	0	0	320	319	1	1
SMAD2	PCBP3	0	0	0	210	1	1
SMAD2	HECTD3	63	0	0	193	1	1
SMAD2	DLK1	0	0	181	198	1	1
SMAD2	SMARCA4	486	0	819	903	1	1
SMAD2	SIRT1	0	0	391	474	1	2
SMAD2	MCL1	0	0	241	240	1	2
SMAD2	RCHY1	0	0	107	176	1	1
SMAD2	CFL1	0	0	217	217	1	1
SMAD2	MAPK14	0	0	455	589	1	2
SMAD2	MEOX2	0	0	122	177	1	1
SMAD2	LMNB2	0	0	142	209	1	1
SMAD2	TIMP3	0	0	360	361	1	1
SMAD2	MAPK10	0	0	123	228	1	2
SMAD2	HIST1H4A	0	0	233	232	1	1
SMAD2	UBA52	130	600	0	637	1	1
SMAD2	PTH1R	0	0	170	213	1	1
SMAD2	SREBF1	0	0	206	223	1	1
SMAD2	UCP1	0	0	181	181	1	2
SMAD2	TCF4	0	0	218	255	1	1
SMAD2	BMP4	0	0	681	831	1	1
SMAD2	ZBTB33	0	0	95	197	1	1
SMAD2	CLIC4	0	0	655	655	1	1
SMAD2	FHL1	270	0	62	291	1	1
SMAD2	WT1	0	0	269	300	1	1
SMAD2	KERA	0	0	134	202	1	1
SMAD2	MSH3	0	0	202	216	1	1
SMAD2	PRKG2	0	0	112	203	1	1
SMAD2	NFKBIA	0	0	408	434	1	2
SMAD2	SAMD7	0	0	261	261	1	1
SMAD2	LEP	0	0	280	280	1	1
SMAD2	SYK	0	0	142	218	1	2
SMAD2	S1PR1	0	0	161	164	1	1
SMAD2	DNM1L	0	0	327	338	1	2
SMAD2	SLC7A7	0	0	0	248	1	1
SMAD2	MYOD1	0	0	466	831	1	1
SMAD2	COL10A1	0	0	299	311	1	1
SMAD2	PMEPA1	0	600	698	876	1	1
SMAD2	POU6F1	0	0	0	286	1	1
SMAD2	SNIP1	192	900	433	950	1	1
SMAD2	VEGFA	0	0	608	610	1	2
SMAD2	NFIA	270	0	107	325	1	1
SMAD2	IRF4	0	0	462	462	1	1
SMAD2	MAPK7	0	0	288	345	1	1
SMAD2	ID3	0	0	369	464	1	1
SMAD2	PTEN	0	0	739	793	1	2
SMAD2	NCOA6	73	0	759	782	1	1
SMAD2	RAB5C	0	0	51	164	1	1
SMAD2	HECW2	0	0	48	180	1	1
SMAD2	CHD4	0	0	88	163	1	1
SMAD2	GFAP	63	0	247	264	1	2
SMAD2	LRCH3	0	0	0	164	1	1
SMAD2	EFNB2	0	0	184	183	1	1
SMAD2	STRAP	270	900	166	935	1	1
SMAD2	CCL20	0	0	183	183	1	1
SMAD2	MTDH	0	0	154	158	1	2
SMAD2	PTK7	0	0	66	159	1	1
SMAD2	CXCL2	0	0	173	173	1	1
SMAD2	COL1A1	0	0	606	740	1	2
SMAD2	ITGB4	257	0	150	356	1	1
SMAD2	RBPJ	0	0	440	461	1	1
SMAD2	HTR2B	0	0	421	430	1	1
SMAD2	TRAT1	0	0	233	232	1	1
SMAD2	SELE	0	0	181	212	1	1
SMAD2	TJP1	0	0	503	522	1	1
SMAD2	DHX8	257	0	0	410	1	1
SMAD2	TGFBR2	0	900	826	987	1	1
SMAD2	ATG7	0	0	233	309	1	2
SMAD2	CDH11	0	0	275	287	1	1
SMAD2	BTG2	0	0	128	263	1	1
SMAD2	IKZF1	0	0	127	168	1	1
SMAD2	ITGB5	0	0	182	211	1	1
SMAD2	RPL38	0	0	0	206	1	1
SMAD2	ACTG1	0	0	260	351	1	1
SMAD2	HIVEP2	0	0	398	429	1	1
SMAD2	RET	0	0	151	202	1	1
SMAD2	PLEKHA7	0	0	0	174	1	1
SMAD2	SIK3	257	0	0	310	1	1
SMAD2	GNAI1	0	0	0	160	1	1
SMAD2	LHCGR	0	0	418	418	1	1
SMAD2	BAZ2B	0	0	70	177	1	1
SMAD2	ENSG00000267261	0	0	0	197	1	1
SMAD2	TYRO3	0	0	124	202	1	1
SMAD2	AXIN1	213	0	555	681	1	1
SMAD2	EIF3F	0	0	120	153	1	1
SMAD2	BAMBI	0	0	627	635	1	1
SMAD2	LRRC1	0	0	0	162	1	1
SMAD2	TRIM63	0	900	373	936	1	1
SMAD2	SHC1	0	0	366	366	1	1
SMAD2	ATM	0	0	322	356	1	2
SMAD2	SFRP1	0	0	254	299	1	1
SMAD2	EZR	0	0	408	408	1	1
SMAD2	SMAD5	257	720	876	793	1	1
SMAD2	FERMT2	0	0	171	189	1	1
SMAD2	MGP	0	0	210	210	1	1
SMAD2	STAMBPL1	213	0	664	724	1	1
SMAD2	BMPR1B	0	800	601	946	1	1
SMAD2	SST	0	0	113	153	1	1
SMAD2	SOCS2	0	0	171	183	1	1
SMAD2	FABP4	0	0	203	203	1	1
SMAD2	ITGAX	0	0	230	229	1	1
SMAD2	PBRM1	0	0	88	173	1	1
SMAD2	USF2	0	0	161	162	1	1
SMAD2	WNT2	0	0	294	613	1	1
SMAD2	HIST2H4A	0	0	233	232	1	1
SMAD2	CHUK	270	0	865	909	1	1
SMAD2	KLF2	0	0	324	399	1	1
SMAD2	ADAMTSL1	0	0	69	179	1	1
SMAD2	GHR	0	0	97	161	1	1
SMAD2	DNAJA2	257	0	0	303	1	1
SMAD2	MEF2A	270	0	177	457	1	1
SMAD2	CRYAB	0	0	67	254	1	2
SMAD2	PRDM1	0	0	193	193	1	1
SMAD2	HDAC1	835	900	574	992	1	2
SMAD2	CSF1	0	0	250	251	1	1
SMAD2	RIN2	0	0	0	207	1	1
SMAD2	IL33	0	0	218	218	1	2
SMAD2	ESRRG	0	0	67	158	1	1
SMAD2	CXCL1	0	0	251	250	1	2
SMAD2	HSPA1B	257	0	0	335	1	1
SMAD2	MMP14	0	0	392	414	1	1
SMAD2	CDC27	270	0	57	308	1	1
SMAD2	WFIKKN2	0	0	170	212	1	1
SMAD2	AFP	0	0	293	357	1	2
SMAD2	DAXX	0	0	203	236	1	1
SMAD2	LIMK1	0	0	204	279	1	1
SMAD2	SLC23A2	0	0	0	195	1	1
SMAD2	CCL11	0	0	155	154	1	1
SMAD2	EEF1A1	130	0	113	210	1	1
SMAD2	FGF19	0	0	60	381	1	1
SMAD2	USP11	0	0	182	181	1	2
SMAD2	NOTCH2	0	0	306	369	1	1
SMAD2	FGF22	0	0	0	367	1	1
SMAD2	LIMS1	0	0	138	150	1	1
SMAD2	BCAR1	0	0	451	451	1	1
SMAD2	ATG12	0	0	137	157	1	2
SMAD2	DLX3	0	0	166	179	1	1
SMAD2	PRMT2	0	0	73	241	1	1
SMAD2	TET1	0	0	160	159	1	1
SMAD2	CD28	0	0	321	321	1	1
SMAD2	CXCL5	0	0	181	181	1	1
SMAD2	NR2C2	0	0	0	155	1	1
SMAD2	GDF11	0	0	682	790	1	1
SMAD2	SDC1	0	0	218	218	1	1
SMAD2	ZMYND11	70	0	54	151	1	1
SMAD2	SNAPIN	70	0	44	234	1	1
SMAD2	ALDH1A1	0	0	255	254	1	1
SMAD2	SFRP2	0	0	214	247	1	1
SMAD2	ADCY10	0	0	95	151	1	1
SMAD2	SUFU	0	0	148	207	1	1
SMAD2	WEE1	0	0	143	170	1	1
SMAD2	FOXI2	0	0	74	152	1	1
SMAD2	TLR2	0	0	266	279	1	2
SMAD2	PIK3CB	0	0	120	170	1	1
SMAD2	CDKN2B	0	900	504	950	1	1
SMAD2	LRP2	0	0	166	165	1	1
SMAD2	ERF	0	0	430	449	1	1
SMAD2	MET	0	0	511	545	1	2
SMAD2	LRRK2	0	0	0	153	1	2
SMAD2	CD86	0	0	203	203	1	1
SMAD2	BGN	0	0	424	434	1	1
SMAD2	HRH3	0	0	292	303	1	1
SMAD2	PGF	0	0	166	165	1	1
SMAD2	CAV3	0	0	150	188	1	1
SMAD2	FZD5	0	0	170	217	1	1
SMAD2	TFG	0	0	364	402	1	1
SMAD2	SOX7	0	0	181	223	1	1
SMAD2	GNAI3	0	0	0	160	1	2
SMAD2	TWIST1	0	0	519	553	1	1
SMAD2	S100A8	0	0	565	584	1	2
SMAD2	HEY2	0	0	213	218	1	1
SMAD2	YWHAZ	0	0	315	330	1	1
SMAD2	FOS	63	0	639	655	1	2
SMAD2	GDF6	0	0	325	412	1	1
SMAD2	RBM39	0	0	81	179	1	1
SMAD2	LMO2	128	0	135	275	1	1
SMAD2	INHBB	0	900	341	948	1	1
SMAD2	ANGPTL4	0	0	194	232	1	1
SMAD2	IRAK3	0	0	90	158	1	1
SMAD2	PTPN11	0	0	260	338	1	1
SMAD2	MSTN	0	900	701	979	1	1
SMAD2	PDX1	0	0	74	166	1	1
SMAD2	CRKL	0	0	135	216	1	1
SMAD2	E2F1	0	0	161	174	1	2
SMAD2	TFE3	0	0	183	183	1	2
SMAD2	HSPA5	0	0	288	288	1	2
SMAD2	FOXP2	0	0	100	237	1	1
SMAD2	NRAS	0	0	170	220	1	1
SMAD2	FGF20	0	0	66	323	1	1
SMAD2	EIF4A2	63	0	85	222	1	1
SMAD2	TIAF1	0	0	189	189	1	1
SMAD2	BTRC	0	0	261	289	1	1
SMAD2	FOXO1	0	900	459	948	1	2
SMAD2	TGFB1I1	0	0	269	281	1	1
SMAD2	EPAS1	0	650	127	696	1	2
SMAD2	ADRBK1	0	0	181	181	1	1
SMAD2	CDK9	270	900	202	938	1	1
SMAD2	DRAP1	63	900	432	942	1	1
SMAD2	SOD2	0	0	187	216	1	2
SMAD2	FGF21	0	0	162	390	1	2
SMAD2	CCNB1	0	0	256	331	1	1
SMAD2	NPPA	0	0	208	223	1	1
SMAD2	ANXA5	0	0	391	453	1	2
SMAD2	WNT8A	0	0	294	352	1	1
SMAD2	HES1	0	0	122	159	1	2
SMAD2	FBXO32	0	0	469	478	1	2
SMAD2	PCSK6	0	0	216	251	1	1
SMAD2	HOXA7	0	0	75	222	1	1
SMAD2	LGALS9	0	0	71	172	1	1
SMAD2	FOXM1	0	0	284	381	1	1
SMAD2	TAGLN	0	0	502	526	1	1
SMAD2	PDP2	0	0	0	262	1	1
SMAD2	PHEX	0	0	83	260	1	1
SMAD2	KLF3	0	0	173	194	1	1
SMAD2	EPO	0	0	261	261	1	2
SMAD2	SIAH1	0	0	181	237	1	1
SMAD2	PLK1	0	0	212	231	1	2
SMAD2	HAVCR1	0	0	165	165	1	1
SMAD2	NOTCH4	270	0	263	451	1	1
SMAD2	SLC2A10	0	0	203	203	1	1
SMAD2	CTDSPL2	0	0	67	177	1	1
SMAD2	IGFBP5	0	0	185	200	1	1
SMAD2	AMER1	0	0	240	239	1	1
SMAD2	NIT1	0	0	57	202	1	1
SMAD2	IFNG	0	0	301	376	1	2
SMAD2	BIRC2	0	0	156	175	1	1
SMAD2	TWSG1	0	0	265	339	1	1
SMAD2	TGFB3	0	900	739	977	1	1
SMAD2	CCL5	0	0	284	284	1	2
SMAD2	POLE	0	0	159	158	1	1
SMAD2	EMR1	0	0	0	173	1	1
SMAD2	TLR4	0	0	391	423	1	2
SMAD2	CHD7	0	0	123	170	1	1
SMAD2	SIX2	0	0	103	324	1	1
SMAD2	LCORL	0	0	152	253	1	1
SMAD2	ZFYVE16	0	900	460	950	1	1
SMAD2	OLIG1	270	0	466	594	1	1
SMAD2	RGMB	0	0	112	151	1	1
SMAD2	JAG2	0	0	242	348	1	1
SMAD2	SNW1	474	650	700	941	1	1
SMAD2	POTEE	0	0	0	155	1	1
SMAD2	NOS2	0	0	164	196	1	2
SMAD2	NF1	0	0	234	250	1	1
SMAD2	HYAL2	270	0	125	362	1	1
SMAD2	SOX3	0	0	171	230	1	1
SMAD2	ALDH1A2	0	0	148	171	1	1
SMAD2	KITLG	0	0	247	253	1	1
SMAD2	COL11A2	0	0	52	182	1	1
SMAD2	EPHA8	0	0	50	262	1	1
SMAD2	TRIM72	0	0	107	192	1	1
SMAD2	DNMT3B	0	0	261	261	1	1
SMAD2	SMOC2	0	0	113	208	1	1
SMAD2	LAMC2	0	0	142	185	1	1
SMAD2	DNMT3A	0	0	252	252	1	2
SMAD2	SOX12	0	0	57	178	1	1
SMAD2	TUBB4A	0	0	140	178	1	1
SMAD2	AOC3	0	0	166	165	1	1
SMAD2	BCL2L1	0	0	369	369	1	2
SMAD2	SOCS7	0	0	161	181	1	1
SMAD2	CDK2	270	0	423	586	1	2
SMAD2	MAP1LC3A	0	0	171	172	1	2
SMAD2	LMTK2	0	0	147	170	1	1
SMAD2	EPHA2	0	0	123	201	1	1
SMAD2	ERBB2IP	734	0	223	817	1	1
SMAD2	HOXA11	0	0	86	169	1	1
SMAD2	CXCR2	0	0	180	193	1	1
SMAD2	RHO	0	0	67	223	1	2
SMAD2	HERC5	0	0	57	188	1	1
SMAD2	XPO1	0	0	219	236	1	1
SMAD2	CALD1	0	0	161	161	1	1
SMAD2	SIRT5	0	0	157	191	1	1
SMAD2	EDN1	0	0	455	468	1	1
SMAD2	HIF1A	0	0	518	534	1	2
SMAD2	SMAD9	130	720	681	754	1	1
SMAD2	WNT7B	0	0	286	303	1	1
SMAD2	TRPM7	0	0	170	200	1	1
SMAD2	IL1B	0	0	556	556	1	2
SMAD2	TRIM66	0	0	162	194	1	1
SMAD2	NKX6-2	0	0	129	160	1	1
SMAD2	SP1	675	900	716	990	1	2
SMAD2	NCR3	0	0	161	161	1	1
SMAD2	UBE2R2	0	0	84	581	1	1
SMAD2	LATS2	222	0	245	417	1	1
SMAD2	ID1	0	0	519	560	1	1
SMAD2	RNF11	0	0	241	298	1	1
SMAD2	SULF2	0	0	134	153	1	1
SMAD2	PPP2R2D	0	0	141	178	1	1
SMAD2	ACVR1C	0	900	711	980	1	1
SMAD2	PRKG1	0	0	260	333	1	1
SMAD2	MPO	0	0	181	186	1	2
SMAD2	CER1	0	0	184	201	1	1
SMAD2	UCP2	0	0	93	188	1	2
SMAD2	TNFRSF19	0	0	58	182	1	1
SMAD2	IL6	0	0	602	620	1	2
SMAD2	ACTR2	0	0	72	168	1	1
SMAD2	H3F3A	0	0	61	159	1	1
SMAD2	KCNA5	0	0	153	212	1	1
SMAD2	BRD2	0	0	81	190	1	1
SMAD2	CBX3	0	0	148	166	1	1
SMAD2	TBX2	0	0	432	492	1	1
SMAD2	E2F6	0	0	167	180	1	1
SMAD2	ZFHX3	0	0	456	456	1	1
SMAD2	DACT2	0	0	388	388	1	1
SMAD2	MYOG	0	0	391	486	1	1
SMAD2	RPS6	0	0	180	179	1	2
SMAD2	TNFRSF1A	0	0	243	242	1	1
SMAD2	FGF13	0	0	467	535	1	1
SMAD2	ADAMTSL2	0	0	398	408	1	1
SMAD2	TRAF4	0	0	218	218	1	1
SMAD2	PRMT1	0	0	120	258	1	1
SMAD2	CD40LG	0	0	172	185	1	1
SMAD2	CBY1	0	0	53	215	1	1
SMAD2	ENTPD1	0	0	150	165	1	1
SMAD2	CCNC	0	900	137	913	1	1
SMAD2	NOTCH1	0	0	746	769	1	2
SMAD2	TBR1	0	0	165	280	1	1
SMAD2	KLF7	0	0	149	215	1	1
SMAD2	LDLRAD4	690	0	141	730	1	1
SMAD2	BMP3	0	0	344	507	1	1
SMAD2	SMO	0	0	0	227	1	1
SMAD2	POTEF	0	0	232	323	1	1
SMAD2	PITX2	0	0	340	411	1	1
SMAD2	LMNA	0	0	323	376	1	2
SMAD2	MUC5B	0	0	128	228	1	1
SMAD2	PTPRD	0	0	99	168	1	1
SMAD2	CSF3	0	0	210	210	1	1
SMAD2	SKOR1	0	0	300	354	1	1
SMAD2	FGF7	0	0	321	458	1	1
SMAD2	MED13	0	0	150	188	1	1
SMAD2	DDIT3	0	0	170	187	1	2
SMAD2	DHH	0	0	124	188	1	1
SMAD2	SGCG	0	0	69	152	1	1
SMAD2	PRKCI	0	0	54	174	1	1
SMAD2	FBLN2	0	0	150	186	1	1
SMAD2	COL5A2	0	0	158	279	1	1
SMAD2	KPNA4	0	0	141	277	1	1
SMAD2	TRIM24	0	0	226	255	1	1
SMAD2	CFTR	0	0	156	162	1	2
SMAD2	FADD	0	0	170	169	1	2
SMAD2	UCHL5	270	0	478	603	1	1
SMAD2	SARM1	0	0	408	462	1	1
SMAD2	SLAIN1	0	0	57	157	1	1
SMAD2	MYD88	0	0	270	273	1	2
SMAD2	HIST1H4I	0	0	233	232	1	1
SMAD2	CDK4	270	0	405	555	1	2
SMAD2	GAS1	0	0	123	159	1	1
SMAD2	TCF21	0	0	148	211	1	1
SMAD2	ERN1	0	0	166	223	1	2
SMAD2	RBP2	0	0	307	307	1	1
SMAD2	HOXD13	213	0	57	276	1	1
SMAD2	GATA3	0	0	391	494	1	1
SMAD2	NR2F1	0	0	122	153	1	1
SMAD2	NF2	0	0	250	250	1	1
SMAD2	POU5F1B	0	0	0	219	1	1
SMAD2	AGO2	0	0	278	283	1	2
SMAD2	TGFA	0	0	323	323	1	1
SMAD2	MKKS	0	0	134	157	1	1
SMAD2	EIF4G3	0	0	0	181	1	1
SMAD2	DKK2	0	0	210	219	1	1
SMAD2	MST1	0	0	127	175	1	2
SMAD2	ADAM9	0	0	92	167	1	1
SMAD2	EZH2	270	0	705	780	1	2
SMAD2	RLIM	0	0	95	154	1	1
SMAD2	STAT3	0	0	667	726	1	2
SMAD2	WNT5B	0	0	323	379	1	1
SMAD2	TSC22D3	0	0	96	160	1	1
SMAD2	PAK1	129	0	147	297	1	2
SMAD2	COL2A1	0	0	373	460	1	2
SMAD2	FOXE3	0	0	142	200	1	1
SMAD2	PAX4	0	0	133	163	1	1
SMAD2	CYBA	0	0	162	162	1	1
SMAD2	PIN1	486	0	81	678	1	1
SMAD2	CTBP2	0	0	150	195	1	1
SMAD2	ZNF8	213	0	0	327	1	1
SMAD2	RBFOX2	0	0	107	262	1	1
SMAD2	HGS	270	0	772	826	1	2
SMAD2	MEN1	0	600	441	775	1	1
SMAD2	TAB1	0	0	310	363	1	1
SMAD2	NOG	0	0	519	538	1	1
SMAD2	APPL1	0	0	134	242	1	1
SMAD2	EVX1	0	0	62	215	1	1
SMAD2	SEMA6A	63	0	185	203	1	1
SMAD2	CTDSP1	270	900	82	933	1	1
SMAD2	FBP2	180	0	0	179	1	1
SMAD2	PIK3CA	270	0	489	637	1	2
SMAD2	NCAN	0	0	166	165	1	1
SMAD2	CERS1	0	0	296	386	1	1
SMAD2	RARG	0	0	123	171	1	1
SMAD2	MMP17	0	0	0	429	1	1
SMAD2	TFAP2B	0	900	59	901	1	1
SMAD2	MYC	462	900	969	998	1	2
SMAD2	GSC	129	0	113	554	1	1
SMAD2	IL1R1	0	0	217	217	1	1
SMAD2	IL18	0	0	261	261	1	2
SMAD2	PAX7	0	0	289	294	1	1
SMAD2	COL11A1	0	0	195	305	1	1
SMAD2	SDHC	0	0	404	417	1	1
SMAD2	IGF1R	0	0	394	477	1	2
SMAD2	TAB2	0	0	217	230	1	2
SMAD2	USF1	0	0	260	260	1	1
SMAD2	HOXA9	213	0	144	343	1	1
SMAD2	ENSG00000279576	0	0	442	442	1	1
SMAD2	PI3	0	0	194	194	1	2
SMAD2	RASAL1	0	0	117	179	1	1
SMAD2	UBE2D1	0	900	103	910	1	1
SMAD2	FGF10	0	0	283	403	1	1
SMAD2	SDHAF2	0	0	161	176	1	1
SMAD2	MECP2	0	0	210	221	1	1
SMAD2	EHMT2	0	0	181	181	1	2
SMAD2	NFE2L2	0	0	282	328	1	2
SMAD2	ZNF423	0	0	123	168	1	1
SMAD2	UBE2K	0	0	94	158	1	1
SMAD2	PLEKHA5	0	0	0	198	1	1
SMAD2	AKT2	0	0	260	390	1	2
SMAD2	SCML2	0	0	0	152	1	1
SMAD2	DSP	0	0	212	233	1	1
SMAD2	FURIN	0	0	405	430	1	1
SMAD2	CD80	0	0	181	181	1	2
SMAD2	MSANTD3-TMEFF1	0	0	0	207	1	1
SMAD2	ZNF442	0	0	118	166	1	1
SMAD2	EID1	0	0	306	306	1	1
SMAD2	F2RL1	0	0	141	160	1	1
SMAD2	MAP2K1	165	0	467	562	1	1
SMAD2	BTC	0	0	160	159	1	1
SMAD2	UBBP4	0	0	0	172	1	1
SMAD2	OSM	0	0	218	218	1	1
SMAD2	MAGI1	0	0	0	180	1	1
SMAD2	SUCO	0	0	55	239	1	1
SMAD2	MEF2D	0	0	103	259	1	2
SMAD2	MYCN	0	0	260	276	1	1
SMAD2	SMAD4	998	900	990	999	1	2
SMAD2	SAMD8	0	0	44	421	1	1
SMAD2	HIST1H4L	0	0	233	232	1	1
SMAD2	HDAC5	0	0	134	218	1	1
SMAD2	ZSCAN10	0	600	0	610	1	1
SMAD2	FHL2	270	0	702	775	1	1
SMAD2	PARD3	270	0	46	294	1	1
SMAD2	CHI3L1	0	0	107	203	1	1
SMAD2	LTBP1	0	0	518	535	1	1
SMAD2	ADIPOQ	0	0	268	269	1	2
SMAD2	PMS1	0	0	167	167	1	1
SMAD2	AMOT	0	0	208	208	1	1
SMAD2	ARG1	0	0	244	243	1	2
SMAD2	SKP2	0	0	233	242	1	2
SMAD2	MEIS2	0	0	74	181	1	1
SMAD2	BTG3	0	0	47	165	1	1
SMAD2	VIM	0	0	417	568	1	2
SMAD2	MOB1A	0	0	184	219	1	1
SMAD2	FZD7	0	0	193	239	1	1
SMAD2	MAGIX	0	0	0	174	1	1
SMAD2	FOXP1	0	600	477	858	1	1
SMAD2	PAK2	0	0	213	286	1	1
SMAD2	TBX3	0	0	294	369	1	1
SMAD2	CLDN3	0	0	150	173	1	1
SMAD2	OTUB1	270	0	478	651	1	1
SMAD2	KLF5	415	0	341	608	1	2
SMAD2	CDX1	0	0	108	203	1	1
SMAD2	TNS1	0	0	235	261	1	1
SMAD2	NFIC	0	0	210	210	1	1
SMAD2	HIST2H3PS2	0	0	450	479	1	1
SMAD2	PXN	0	0	315	331	1	1
SMAD2	CTGF	0	0	747	791	1	1
SMAD2	HES5	0	0	164	170	1	1
SMAD2	CSK	0	0	136	195	1	1
SMAD2	CISH	70	0	212	246	1	1
SMAD2	PDGFA	0	0	309	309	1	1
SMAD2	PTGER4	0	0	193	206	1	1
SMAD2	CPT1B	0	0	47	243	1	1
SMAD2	FKBP1A	0	900	350	932	1	2
SMAD2	NR3C1	0	650	289	748	1	1
SMAD2	PRF1	0	0	219	219	1	1
SMAD2	SMARCB1	0	0	123	151	1	1
SMAD2	ACVR1	0	800	738	967	1	1
SMAD2	COL5A1	0	0	252	383	1	1
SMAD2	LIF	0	0	325	325	1	2
SMAD2	CX3CR1	0	0	211	211	1	1
SMAD2	SNRPD2	0	0	439	439	1	1
SMAD2	CDKN1C	0	0	260	306	1	1
SMAD2	POTEJ	0	0	0	155	1	1
SMAD2	RPL22L1	0	0	125	217	1	1
SMAD2	SCMH1	0	0	54	172	1	1
SMAD2	ITGA1	0	0	151	155	1	1
SMAD2	MRC2	0	0	142	157	1	1
SMAD2	CEBPD	0	0	179	196	1	1
SMAD2	RPTOR	0	0	265	281	1	2
SMAD2	NES	0	0	341	360	1	2
SMAD2	DAB2	270	900	496	964	1	1
SMAD2	TIE1	0	0	180	197	1	1
SMAD2	BPTF	270	0	125	424	1	1
SMAD2	GNAS	63	0	151	191	1	1
SMAD2	RPAP2	0	0	0	155	1	1
SMAD2	KLF13	0	0	132	154	1	1
SMAD2	CASP9	0	0	319	319	1	2
SMAD2	NANOG	0	600	722	892	1	2
SMAD2	GDF2	0	0	562	649	1	1
SMAD2	RPS6KA3	0	0	193	210	1	1
SMAD2	CHEK2	0	0	209	227	1	1
SMAD2	NRP1	0	0	282	282	1	1
SMAD2	MAPK9	213	0	211	380	1	2
SMAD2	IL17A	0	0	425	424	1	2
SMAD2	AKR1B1	0	0	457	457	1	1
SMAD2	RGMA	0	0	165	184	1	1
SMAD2	ETS1	0	0	519	567	1	1
SMAD2	PBX2	0	0	48	202	1	1
SMAD2	CSNK2A2	0	0	134	158	1	1
SMAD2	IL9	0	0	250	339	1	1
SMAD2	NOTCH3	0	0	344	410	1	1
SMAD2	FBLN1	0	0	108	190	1	1
SMAD2	CNN2	0	0	67	233	1	1
SMAD2	PKNOX1	0	0	697	747	1	1
SMAD2	MYLK	0	0	219	219	1	1
SMAD2	TRIM62	130	0	125	231	1	1
SMAD2	HESX1	0	0	130	181	1	1
SMAD2	CASP8	0	0	321	321	1	2
SMAD2	CDK19	0	0	106	303	1	1
SMAD2	HSPG2	0	0	214	232	1	1
SMAD2	KAT2A	270	0	127	395	1	1
SMAD2	BCL9	0	0	123	152	1	1
SMAD2	ITGB1	0	0	417	454	1	1
SMAD2	FAP	0	0	134	184	1	2
SMAD2	DCAF7	257	0	0	256	1	1
SMAD2	PIWIL4	0	0	159	177	1	1
SMAD2	HERC4	0	0	0	224	1	1
SMAD2	DSPP	0	0	357	357	1	1
SMAD2	MFAP5	0	0	170	175	1	1
SMAD2	BSG	0	0	145	163	1	1
SMAD2	DPP4	0	0	183	200	1	1
SMAD2	NR3C2	0	0	156	180	1	1
SMAD2	TSC22D1	0	0	150	256	1	1
SMAD2	LGALS4	0	0	234	254	1	1
SMAD2	SPNS2	0	0	66	179	1	1
SMAD2	IL1A	0	0	304	304	1	1
SMAD2	CCL4	0	0	210	210	1	1
SMAD2	RHOB	0	0	203	269	1	1
SMAD2	SUZ12	0	0	234	251	1	1
SMAD2	BMP10	0	0	370	451	1	1
SMAD2	MAPKAPK2	0	0	164	165	1	1
SMAD2	GLI2	270	0	351	541	1	2
SMAD2	HIST1H4E	0	0	233	232	1	1
SMAD2	CDK6	0	0	324	338	1	2
SMAD2	KMT2B	0	0	123	161	1	1
SMAD2	NEUROG3	0	0	228	227	1	1
SMAD2	ZEB2	359	0	621	764	1	1
SMAD2	FZD8	0	0	147	195	1	1
SMAD2	LEFTY2	0	0	469	650	1	1
SMAD2	FRK	0	0	60	286	1	1
SMAD2	KLF12	0	0	143	165	1	1
SMAD2	RERG	0	0	0	171	1	1
SMAD2	PLG	0	0	459	479	1	1
SMAD2	BMP7	0	0	662	742	1	1
SMAD2	ADAMTS10	0	0	328	339	1	1
SMAD2	PDPN	0	0	193	193	1	1
SMAD2	RAP2B	0	0	103	155	1	1
SMAD2	FGF17	0	0	75	371	1	1
SMAD2	RHOA	63	0	627	669	1	2
SMAD2	PARP1	0	600	181	665	1	2
SMAD2	GDF10	0	0	438	510	1	1
SMAD2	EPCAM	0	0	341	361	1	2
SMAD2	DAND5	0	0	293	303	1	1
SMAD2	ETV4	270	0	166	386	1	1
SMAD2	HSPA8	0	900	415	939	1	2
SMAD2	INSR	270	0	165	452	1	1
SMAD2	JUP	0	0	67	176	1	1
SMAD2	TCF7L1	0	0	171	298	1	1
SMAD2	ITGA11	0	0	171	171	1	1
SMAD2	RNF43	0	0	166	197	1	1
SMAD2	CXCL12	0	0	391	390	1	2
SMAD2	FGF4	0	0	294	416	1	1
SMAD2	KDM1A	0	0	218	269	1	2
SMAD2	KLRK1	0	0	218	231	1	1
SMAD2	PIWIL1	0	0	166	184	1	1
SMAD2	TPM1	0	0	147	165	1	1
SMAD2	ESR2	213	0	213	373	1	1
SMAD2	R3HDM1	0	0	66	184	1	1
SMAD2	SEMA4A	0	0	151	150	1	1
SMAD2	STK4	0	0	112	275	1	1
SMAD2	LTBP2	0	0	323	337	1	1
SMAD2	PBX1	0	600	159	717	1	1
SMAD2	FOXD3	0	0	181	238	1	1
SMAD2	MXI1	0	0	89	186	1	1
SMAD2	CD24	0	0	273	273	1	2
SMAD2	ENSG00000258724	0	0	171	214	1	1
SMAD2	ZEB1	270	0	732	813	1	2
SMAD2	SIRT7	0	0	230	261	1	2
SMAD2	IL22	0	0	182	181	1	1
SMAD2	FBXW7	0	0	322	321	1	2
SMAD2	HPGDS	0	0	212	212	1	1
SMAD2	SP7	0	0	404	428	1	1
SMAD2	SETDB1	0	0	150	183	1	1
SMAD2	PAX8	0	0	123	163	1	1
SMAD2	IL3	0	0	166	165	1	1
SMAD2	FOSL1	0	0	769	774	1	1
SMAD2	SUV39H1	0	0	184	196	1	1
SMAD2	PKNOX2	0	0	0	161	1	1
SMAD2	CEBPA	0	0	464	475	1	1
SMAD2	NEUROD1	0	0	207	207	1	1
SMAD2	STUB1	270	0	436	571	1	2
SMAD2	DNMT1	0	0	342	400	1	2
SMAD2	WNT6	0	0	270	287	1	1
SMAD2	CD40	0	0	233	232	1	2
SMAD2	TLE1	0	0	112	151	1	1
SMAD2	CAV2	0	0	135	189	1	1
SMAD2	ADAMTS5	0	0	320	332	1	1
SMAD2	FOXG1	213	900	180	941	1	1
SMAD2	ACTB	0	0	681	718	1	2
SMAD2	INS	0	0	519	574	1	2
SMAD2	CLDN5	0	0	189	189	1	1
SMAD2	HOXB1	0	0	81	193	1	1
SMAD2	F2RL2	0	0	0	181	1	1
SMAD2	PDGFD	0	0	173	173	1	1
SMAD2	ZNF580	0	0	150	172	1	1
SMAD2	HIST1H4J	0	0	233	232	1	1
SMAD2	GLI3	213	0	268	426	1	1
SMAD2	PBX3	0	0	88	235	1	1
SMAD2	INHBE	0	0	125	253	1	1
SMAD2	ANGPT1	0	0	253	270	1	1
SMAD2	PROM1	0	0	392	392	1	2
SMAD2	SIRT3	0	0	211	325	1	2
SMAD2	ROS1	0	0	54	215	1	1
SMAD2	KEAP1	0	300	211	436	1	2
SMAD2	B2M	0	0	210	228	1	1
SMAD2	CHEK1	0	0	210	210	1	2
SMAD2	PLAT	0	0	206	247	1	1
SMAD2	AKT1S1	0	0	145	171	1	1
SMAD2	CASP1	0	0	217	228	1	2
SMAD2	CCR3	0	0	97	173	1	1
SMAD2	CAV1	270	900	559	965	1	2
SMAD2	SRF	0	0	391	431	1	1
SMAD2	HSPA1A	0	0	134	225	1	1
SMAD2	SLC33A1	0	0	0	453	1	1
SMAD2	MAP2K3	0	0	327	359	1	1
SMAD2	CDC20	0	0	134	170	1	1
SMAD2	WDR5	0	0	173	191	1	1
SMAD2	BCL2L11	0	0	372	372	1	2
SMAD2	DLL4	0	0	260	276	1	1
SMAD2	CD109	0	0	288	288	1	1
SMAD2	TNKS	0	0	150	184	1	1
SMAD2	NR2F2	0	0	155	185	1	1
SMAD2	MAML1	0	0	166	234	1	1
SMAD2	MAPK12	0	0	181	230	1	1
SMAD2	KL	0	0	247	254	1	2
SMAD2	BATF	0	0	241	257	1	1
SMAD2	PLCG1	0	0	150	199	1	1
SMAD2	MYL7	0	0	123	171	1	1
SMAD2	DVL3	0	0	134	287	1	1
SMAD2	UBE3C	0	0	0	193	1	1
SMAD2	RGCC	270	0	692	765	1	1
SMAD2	MAFB	0	0	135	189	1	1
SMAD2	TICAM1	0	0	48	211	1	2
SMAD2	NKX2-2	0	0	134	211	1	1
SMAD2	TLE4	0	0	108	158	1	1
SMAD2	VCP	0	0	248	323	1	2
SMAD2	LCK	270	0	194	490	1	1
SMAD2	IL17RA	0	0	142	166	1	1
SMAD2	CCRL2	0	0	140	154	1	1
SMAD2	IL37	0	0	91	211	1	1
SMAD2	CCR5	0	0	145	169	1	1
SMAD2	CABLES1	0	0	113	155	1	1
SMAD2	MED12	0	0	181	201	1	1
SMAD2	USP4	0	0	287	287	1	1
SMAD2	FZD6	0	0	147	241	1	1
SMAD2	TTC3	0	0	70	160	1	1
SMAD2	CD69	0	0	170	184	1	1
SMAD2	SHH	0	0	459	499	1	2
SMAD2	CSNK1A1	0	0	194	240	1	1
SMAD2	PNMT	0	0	0	154	1	1
SMAD2	LRRC32	0	0	216	229	1	1
SMAD2	IGFBP3	0	0	299	299	1	2
SMAD2	ARID1B	270	0	447	607	1	1
SMAD2	DLL1	0	0	490	501	1	1
SMAD2	CD8A	0	0	420	420	1	1
SMAD2	ANGPT2	0	0	193	209	1	1
SMAD2	TOB1	213	0	505	680	1	1
SMAD2	TCF7	0	0	165	310	1	1
SMAD2	TRIM3	0	0	0	214	1	1
SMAD2	CRK	0	0	134	198	1	1
SMAD2	ETV1	0	0	130	158	1	1
SMAD2	ZBTB17	0	900	69	905	1	1
SMAD2	IGF2BP3	0	0	75	151	1	1
SMAD2	MMP2	0	0	603	619	1	2
SMAD2	S100A2	0	0	48	228	1	1
SMAD2	IRF3	270	0	162	362	1	2
SMAD2	TRIM2	0	0	0	214	1	1
SMAD2	ERBB2	0	0	459	486	1	2
SMAD2	HMGA2	0	900	406	948	1	1
SMAD2	ARG2	0	0	161	161	1	1
SMAD2	FOXF2	0	0	142	260	1	1
SMAD2	TLR9	0	0	170	184	1	2
SMAD2	SLIT3	0	0	135	150	1	1
SMAD2	IL6ST	0	0	169	169	1	1
SMAD2	MAP3K1	0	900	270	934	1	1
SMAD2	CCNE2	0	0	181	259	1	1
SMAD2	IGF2R	0	0	174	173	1	1
SMAD2	NR1I2	0	0	122	181	1	1
SMAD2	CXCL10	0	0	235	235	1	2
SMAD2	EDNRB	0	0	148	186	1	1
SMAD2	RHOC	0	0	245	315	1	1
SMAD2	IPO8	0	0	112	336	1	1
SMAD2	FGF3	0	0	157	387	1	1
SMAD2	CSMD3	0	0	86	152	1	1
SMAD2	SIRT4	0	0	163	197	1	1
SMAD2	BIRC5	0	0	140	182	1	2
SMAD2	ITGB6	0	0	261	277	1	1
SMAD2	GSK3A	108	0	95	279	1	1
SMAD2	CHRD	0	0	503	686	1	1
SMAD2	CDC16	270	0	0	293	1	1
SMAD2	NID1	0	0	178	192	1	1
SMAD2	IL11	0	0	391	390	1	1
SMAD2	CCNG2	270	0	193	411	1	1
SMAD2	WWOX	0	0	155	190	1	1
SMAD2	ID2	0	0	405	489	1	1
SMAD2	EMD	0	0	161	161	1	1
SMAD2	RUNX2	270	0	816	869	1	2
SMAD2	PPP2R4	0	0	268	268	1	1
SMAD2	CEBPG	0	0	48	165	1	1
SMAD2	XIAP	0	0	284	299	1	2
SMAD2	FMOD	0	0	293	321	1	1
SMAD2	PCBP4	0	650	0	650	1	1
SMAD2	ANKS6	0	0	701	706	1	1
SMAD2	SATB1	0	0	447	459	1	1
SMAD2	KLF4	0	600	707	896	1	2
SMAD2	COL6A1	0	0	193	222	1	1
SMAD2	IKBKB	0	0	324	384	1	2
SMAD2	COL1A2	270	0	596	706	1	1
SMAD2	RXFP1	0	0	295	335	1	1
SMAD2	ATF6	0	0	170	169	1	2
SMAD2	ACE2	0	0	220	273	1	2
SMAD2	SPATA5	0	0	0	158	1	1
SMAD2	FGFR1	0	0	391	443	1	1
SMAD2	HOXA10	0	0	103	161	1	1
SMAD2	SEMA7A	0	0	188	188	1	1
SMAD2	ATF4	0	0	125	190	1	2
SMAD2	PEAK1	0	0	134	159	1	1
SMAD2	CD4	0	0	504	505	1	2
SMAD2	FOXA1	0	0	282	372	1	1
SMAD2	PTHLH	0	0	390	426	1	1
SMAD2	SGK3	0	0	134	175	1	1
SMAD2	PRDM16	270	0	454	627	1	1
SMAD2	MKI67	0	0	75	326	1	2
SMAD2	LHX2	0	0	209	223	1	1
SMAD2	TEAD2	0	0	161	213	1	1
SMAD2	PPARG	0	0	690	699	1	2
SMAD2	SLIT2	0	0	134	171	1	1
SMAD2	UBE3A	0	0	195	322	1	1
SMAD2	TGFB2	0	900	762	981	1	1
SMAD2	CAPN1	0	0	113	167	1	2
SMAD2	AKT1	408	0	711	853	1	2
SMAD2	GIPC1	0	0	184	195	1	1
SMAD2	GPC3	0	0	156	271	1	1
SMAD2	NUP214	462	900	822	989	1	1
SMAD2	CDKN1B	0	0	391	402	1	2
SMAD2	STK3	0	0	0	238	1	1
SMAD2	CTCF	0	0	182	222	1	1
SMAD2	RB1	0	0	233	256	1	2
SMAD2	HECTD1	0	0	0	192	1	1
SMAD2	TSC2	270	0	416	556	1	2
SMAD2	HACE1	0	0	0	184	1	1
SMAD2	RBX1	0	800	115	815	1	1
SMAD2	F2R	0	0	170	169	1	1
SMAD2	MSX2	0	0	324	394	1	1
SMAD2	ZBTB7C	0	0	163	184	1	1
SMAD2	JAK1	0	0	300	353	1	2
SMAD2	MMP12	0	0	233	251	1	1
SMAD2	ANPEP	0	0	150	160	1	1
SMAD2	NTN1	0	0	113	173	1	1
SMAD2	RASSF1	0	0	183	234	1	1
SMAD2	PIAS4	486	0	95	555	1	1
SMAD2	NFATC2	0	0	261	275	1	1
SMAD2	ADAMTSL3	0	0	57	217	1	1
SMAD2	CNN3	0	0	0	196	1	1
SMAD2	HAS2	0	0	390	390	1	1
SMAD2	LIN28B	0	0	241	257	1	1
SMAD2	NRG1	0	0	134	166	1	2
SMAD2	TCHP	0	0	456	456	1	1
SMAD2	SEC13	0	0	0	152	1	1
SMAD2	HMOX1	0	0	294	294	1	2
SMAD2	TCF12	270	0	213	429	1	1
SMAD2	STAT6	0	0	341	390	1	1
SMAD2	ING2	270	0	442	581	1	1
SMAD2	A2M	0	0	155	154	1	1
SMAD2	LRRC7	0	0	0	162	1	1
SMAD2	WWP2	474	0	228	655	1	1
SMAD2	EIF2AK3	0	0	390	390	1	2
SMAD2	FLT1	0	0	322	336	1	1
SMAD2	TNFRSF18	0	0	208	208	1	1
SMAD2	CADM1	0	0	154	153	1	1
SMAD2	LGALS3	0	0	273	292	1	2
SMAD2	CIB1	0	0	94	170	1	1
SMAD2	SLC25A5	131	0	0	165	1	1
SMAD2	SMARCC1	669	0	103	706	1	1
SMAD2	MKL1	0	0	363	363	1	1
SMAD2	MCM3	0	0	95	162	1	1
SMAD2	EPHB3	0	0	96	158	1	1
SMAD2	IRS4	0	0	74	215	1	1
SMAD2	SMURF2	897	900	987	999	1	1
SMAD2	MEOX1	0	0	97	154	1	1
SMAD2	STAMBP	213	0	817	850	1	1
SMAD2	ACTL6A	0	0	60	286	1	1
SMAD2	EED	0	0	107	150	1	1
SMAD2	ADAM12	0	0	254	315	1	1
SMAD2	SRC	0	0	559	625	1	2
SMAD2	IL36B	0	0	64	157	1	1
SMAD2	METTL3	270	0	878	907	1	2
SMAD2	KDM6A	0	0	213	226	1	1
SMAD2	PCSK9	0	0	172	171	1	1
SMAD2	CRIP2	0	0	112	254	1	1
SMAD2	USP2	270	0	72	306	1	1
SMAD2	ZFPM2	0	0	121	163	1	1
SMAD2	CD47	0	0	167	173	1	2
SMAD2	ENSG00000279890	0	0	0	166	1	1
SMAD2	EEA1	0	0	243	254	1	2
SMAD2	CREB5	0	0	91	165	1	1
SMAD2	STAR	0	0	157	167	1	1
SMAD2	SAP30	0	900	0	902	1	1
SMAD2	EPHA1	0	0	95	157	1	1
SMAD2	HDAC7	0	0	142	167	1	1
SMAD2	RCC1	0	0	134	194	1	1
SMAD2	CD274	0	0	284	284	1	2
SMAD2	HOXB7	0	0	81	246	1	1
SMAD2	HERC3	0	0	0	193	1	1
SMAD2	DVL2	0	0	219	357	1	2
SMAD2	PAXIP1	70	0	827	838	1	1
SMAD2	WNT8B	0	0	252	281	1	1
SMAD2	GREM2	0	0	157	245	1	1
SMAD2	ABCG2	0	0	233	232	1	1
SMAD2	FOXC2	0	0	359	415	1	1
SMAD2	SERPINE2	0	0	108	540	1	1
SMAD2	EGR2	0	0	195	215	1	1
SMAD2	LOX	0	0	457	459	1	2
SMAD2	IRS1	0	0	291	296	1	2
SMAD2	SGK1	0	0	203	233	1	2
SMAD2	PRMT8	0	0	0	183	1	1
SMAD2	CBL	0	0	202	216	1	1
SMAD2	SAG	0	0	157	198	1	1
SMAD2	EDNRA	0	0	144	158	1	1
SMAD2	NTRK1	0	0	267	333	1	1
SMAD2	SMTN	0	0	269	294	1	1
SMAD2	IDUA	0	0	0	206	1	1
SMAD2	SERPINE1	0	900	706	975	1	1
SMAD2	AHR	0	0	231	230	1	2
SMAD2	NCOR1	0	900	473	945	1	1
SMAD2	CDK1	0	0	292	322	1	2
SMAD2	PGR	0	0	283	303	1	1
SMAD2	HIST1H4B	0	0	233	251	1	1
SMAD2	MUC1	0	0	155	154	1	1
SMAD2	REM1	0	0	0	396	1	1
SMAD2	AGTR1	0	0	419	428	1	1
SMAD2	ADRB2	0	0	142	174	1	1
SMAD2	RPS6KB1	0	0	420	445	1	2
SMAD2	DUSP6	0	0	135	382	1	1
SMAD2	PDPK1	0	0	144	167	1	2
SMAD2	TAL1	0	0	158	169	1	1
SMAD2	TBX1	0	0	181	226	1	1
SMAD2	KLC2	0	0	320	734	1	1
SMAD2	ELMO2	0	0	0	212	1	1
SMAD2	DDX5	0	0	539	606	1	1
SMAD2	HPGD	0	0	162	175	1	1
SMAD2	CAT	0	0	310	309	1	2
SMAD2	GFI1	0	0	137	196	1	1
SMAD2	WNT10B	0	0	294	310	1	1
SMAD2	MKL2	0	0	145	309	1	1
SMAD2	MCM7	0	0	128	173	1	1
SMAD2	POU5F1	0	600	585	859	1	2
SMAD2	HGF	0	0	519	536	1	2
SMAD2	MAGI2	0	0	63	198	1	1
SMAD2	CCT6A	131	0	65	152	1	1
SMAD2	BMPR2	0	800	652	948	1	1
SMAD2	MECOM	270	0	430	577	1	1
SMAD2	CANX	0	0	139	157	1	2
SMAD2	ADAMTS3	0	0	184	198	1	1
SMAD2	RASA1	142	0	124	326	1	1
SMAD2	ZFYVE9	972	900	989	999	1	1
SMAD2	SMAD6	270	800	757	904	1	1
SMAD2	FOXA2	0	0	456	524	1	1
SMAD2	BCL2	0	0	136	157	1	2
SMAD2	MYB	0	0	211	245	1	1
SMAD2	SPRY1	0	0	239	245	1	1
SMAD2	FGF16	0	0	0	376	1	1
SMAD2	HPRT1	0	0	260	260	1	1
SMAD2	TOB2	0	0	165	314	1	1
SMAD2	DDIT4	0	0	136	169	1	2
SMAD2	ITSN1	0	0	142	208	1	1
SMAD2	SLC23A1	0	0	0	258	1	1
SMAD2	CTLA4	0	0	391	390	1	2
SMAD2	LIN28A	0	650	264	753	1	1
SMAD2	EEF2	0	0	90	154	1	2
SMAD2	ITCH	270	0	260	541	1	1
SMAD2	PAX3	0	0	320	319	1	1
SMAD2	PLAG1	0	0	108	154	1	1
SMAD2	PPP1R15A	0	0	203	218	1	2
SMAD2	RBBP7	0	900	63	907	1	1
SMAD2	PDGFC	0	0	229	228	1	1
SMAD2	NFAT5	0	0	144	366	1	1
SMAD2	TFAP2C	0	0	166	165	1	1
SMAD2	RBFOX3	0	0	134	161	1	1
SMAD2	ZNF512B	0	0	73	176	1	1
SMAD2	DDX17	0	0	324	407	1	1
SMAD2	SNAI3	0	0	206	265	1	1
SMAD2	ERCC3	63	0	0	194	1	1
SMAD2	RGS3	0	0	818	822	1	1
SMAD2	MMP3	0	0	427	534	1	1
SMAD2	PIAS2	0	0	113	216	1	1
SMAD2	ASCC1	0	0	0	174	1	1
SMAD2	WISP1	0	0	284	307	1	1
SMAD2	VDR	0	0	264	339	1	2
SMAD2	SIX3	0	0	181	258	1	1
SMAD2	TRAP1	0	0	0	212	1	2
SMAD2	AQP5	0	0	161	178	1	1
SMAD2	HOXA3	0	0	70	218	1	1
SMAD2	SIN3A	0	900	166	925	1	1
SMAD2	MEF2C	270	0	231	451	1	1
SMAD2	MMP25	0	0	0	427	1	1
SMAD2	NT5E	0	0	294	299	1	1
SMAD2	KRT14	0	0	294	294	1	1
SMAD2	ITK	0	0	91	176	1	1
SMAD2	NFYC	270	0	66	304	1	1
SMAD2	SMOC1	0	0	143	226	1	1
SMAD2	RNF4	0	0	103	165	1	1
SMAD2	MSX1	0	0	306	381	1	1
SMAD2	TNF	0	0	564	603	1	2
SMAD2	THBS2	0	0	242	241	1	1
SMAD2	C1orf116	257	0	0	256	1	1
SMAD2	ARNTL	0	0	136	154	1	1
SMAD2	PLOD2	0	0	113	155	1	1
SMAD2	MMP27	0	0	0	427	1	1
SMAD2	DDX53	0	0	134	162	1	1
SMAD2	FOXL2	0	0	721	740	1	1
SMAD2	TBX18	0	0	150	264	1	1
SMAD2	DNAJC7	130	0	0	193	1	1
SMAD2	IRF7	270	0	134	340	1	1
SMAD2	ATF3	270	0	293	517	1	2
SMAD2	WFIKKN1	0	0	90	154	1	1
SMAD2	CDH5	0	0	420	434	1	1
SMAD2	SCN4A	0	0	0	582	1	1
SMAD2	HECW1	0	0	64	194	1	1
SMAD2	MMP8	0	0	250	454	1	1
SMAD2	FHL3	270	0	0	276	1	1
SMAD2	ZNF451	0	0	90	160	1	1
SMAD2	RSPO1	0	0	194	194	1	1
SMAD2	CD9	0	0	203	220	1	1
SMAD2	GCG	0	0	204	204	1	1
SMAD2	NFKB2	0	0	183	255	1	1
SMAD2	CCND2	0	0	290	321	1	1
SMAD2	TFAP2A	0	0	445	445	1	1
SMAD2	TFRC	0	0	166	184	1	1
SMAD2	AGT	0	0	125	516	1	1
SMAD2	IL5	0	0	269	269	1	1
SMAD2	RPS6KA2	0	0	184	183	1	1
SMAD2	TBP	0	0	230	229	1	1
SMAD2	HABP2	0	0	70	153	1	1
SMAD2	FN1	0	0	748	816	1	2
SMAD2	RAG2	0	0	96	203	1	1
SMAD2	RARS	0	0	162	178	1	1
SMAD2	ESRP1	0	0	165	177	1	1
SMAD2	MMP13	0	0	502	622	1	2
SMAD2	SETDB2	0	0	55	154	1	1
SMAD2	ELANE	0	0	190	202	1	1
SMAD2	ACVRL1	0	0	593	660	1	1
SMAD2	PRKCA	0	0	268	268	1	1
SMAD2	CDC25B	0	0	113	225	1	1
SMAD2	RIPK4	0	0	74	166	1	1
SMAD2	SETD2	0	0	90	400	1	1
SMAD2	DLX1	0	0	112	181	1	1
SMAD2	UBE3B	0	0	0	194	1	1
SMAD2	CAMK2A	600	900	48	958	1	2
SMAD2	UBC	0	600	125	685	1	2
SMAD2	TEAD4	0	0	448	483	1	1
SMAD2	LAMA1	0	0	112	172	1	1
SMAD2	SERPINB5	0	0	150	253	1	1
SMAD2	MAP1LC3B	0	0	195	195	1	2
SMAD2	TIMP2	0	0	451	457	1	1
SMAD2	SDC2	0	0	213	213	1	1
SMAD2	INHBC	0	0	81	200	1	1
SMAD2	LOR	0	0	157	156	1	1
SMAD2	HAND2	0	0	150	178	1	1
SMAD2	SPHK1	0	0	193	193	1	2
SMAD2	MST1R	0	0	108	169	1	1
SMAD2	TSG101	0	0	150	168	1	2
SMAD2	NKX2-1	0	0	234	282	1	1
SMAD2	KCNN4	0	0	180	179	1	1
SMAD2	TERT	0	0	272	285	1	2
SMAD2	CXCR3	0	0	150	164	1	1
SMAD2	YAP1	270	800	772	978	1	2
SMAD2	OTX2	0	0	419	424	1	1
SMAD2	MYBL2	0	0	123	183	1	1
SMAD2	ELN	0	0	519	537	1	1
SMAD2	IRF1	0	0	202	211	1	2
SMAD2	KLF11	0	0	268	344	1	1
SMAD2	INHA	0	0	295	395	1	1
SMAD2	LGR5	0	0	261	274	1	1
SMAD2	BMP8A	0	0	127	239	1	1
SMAD2	EDAR	0	0	0	188	1	1
SMAD2	PRKD1	0	0	170	169	1	1
SMAD2	PDCD1	0	0	144	167	1	2
SMAD2	SMAD7	678	900	896	979	1	1
SMAD2	IFNB1	0	0	216	216	1	1
SMAD2	ESR1	486	0	811	903	1	2
SMAD2	MSH2	0	0	270	285	1	1
SMAD2	RGS2	0	0	97	639	1	1
SMAD2	PRL	0	0	167	174	1	1
SMAD2	LMNB1	0	0	244	303	1	1
SMAD2	TLE3	0	0	108	158	1	1
SMAD2	MYOCD	270	0	573	689	1	1
SMAD2	EOMES	0	0	974	978	1	1
SMAD2	NKX2-3	0	0	45	167	1	2
SMAD2	OVOL1	0	0	205	228	1	1
SMAD2	TBX6	0	0	205	374	1	1
SMAD2	PSMC3	0	0	0	155	1	1
SMAD2	TNFRSF9	0	0	120	184	1	1
SMAD2	KAT5	0	0	135	159	1	1
SMAD2	RORC	0	0	181	188	1	1
SMAD2	CDX2	0	0	325	354	1	1
SMAD2	NGFR	0	0	170	169	1	1
SMAD2	E2F3	0	0	218	231	1	1
SMAD2	MARK2	0	0	427	432	1	1
SMAD2	BUB3	257	0	81	348	1	1
SMAD2	CHURC1	0	0	125	221	1	1
SMAD2	HIST1H4K	0	0	233	232	1	1
SMAD2	HOXD11	0	0	92	151	1	1
SMAD2	NLK	0	0	113	333	1	1
SMAD2	RARB	73	0	104	160	1	1
SMAD2	AMBRA1	0	0	54	247	1	2
SMAD2	CCNA1	0	0	72	155	1	1
SMAD2	NFE2L1	0	0	53	173	1	1
SMAD2	ENSG00000273398	0	0	0	159	1	1
SMAD2	KIT	0	0	341	354	1	2
SMAD2	COMMD3-BMI1	0	0	296	311	1	1
SMAD2	GAPDHS	0	0	0	313	1	1
SMAD2	BHLHE41	0	0	175	175	1	1
SMAD2	NTRK3	0	0	93	175	1	1
SMAD2	TERF1	63	0	107	165	1	1
SMAD2	E2F5	0	600	304	716	1	1
SMAD2	AGO1	0	0	145	181	1	1
SMAD2	NFATC1	0	0	441	441	1	2
SMAD2	PAPOLA	70	0	253	292	1	1
SMAD2	MMP11	0	0	95	459	1	1
SMAD2	FZD9	0	0	144	187	1	1
SMAD2	CHL1	0	0	107	156	1	1
SMAD2	ACTR1A	0	0	112	180	1	1
SMAD2	ACSL4	0	0	57	244	1	1
SMAD2	BMPR1A	0	800	615	948	1	1
SMAD2	HHEX	0	0	181	232	1	1
SMAD2	UBE2S	0	0	157	171	1	1
SMAD2	PPP3R1	0	0	92	236	1	1
SMAD2	FGFR4	0	0	174	245	1	1
SMAD2	IL10	0	0	529	529	1	2
SMAD2	SNAI1	0	0	849	869	1	1
SMAD2	FLT3	0	0	150	167	1	2
SMAD2	IRAK4	0	0	112	195	1	1
SMAD2	DMD	0	0	147	320	1	2
SMAD2	FOSB	0	0	144	185	1	1
SMAD2	GDF5	0	0	407	487	1	1
SMAD2	WNT10A	0	0	277	294	1	1
SMAD2	SMARCC2	486	0	90	537	1	1
SMAD2	GDF15	0	0	413	488	1	1
SMAD2	FOSL2	0	0	155	286	1	1
SMAD2	AREL1	0	0	0	174	1	1
SMAD2	ATP1B4	0	650	0	652	1	1
SMAD2	SOX10	0	0	150	534	1	1
SMAD2	CCL22	0	0	181	181	1	1
SMAD2	CCL3	0	0	207	207	1	1
SMAD2	ENG	0	0	561	561	1	2
SMAD2	MDM4	0	0	112	248	1	1
SMAD2	FGF12	0	0	0	375	1	1
SMAD2	IGF2	0	0	325	325	1	1
SMAD2	TEAD1	0	0	281	325	1	1
SMAD2	CDKN2A	0	0	420	429	1	2
SMAD2	ARRB2	0	0	162	168	1	1
SMAD2	RPS27A	410	600	81	767	1	1
SMAD2	GUSB	0	0	147	293	1	1
SMAD2	CCNG1	0	0	103	272	1	1
SMAD2	FGF8	0	0	294	453	1	1
SMAD2	SALL4	0	600	180	692	1	1
SMAD2	KRT7	0	0	181	181	1	1
SMAD2	CDC34	0	0	74	576	1	1
SMAD2	S100B	0	0	144	162	1	1
SMAD2	GSK3B	0	0	391	643	1	2
SMAD2	MRC1	0	0	240	253	1	1
SMAD2	INSRR	0	0	0	173	1	1
SMAD2	RIN1	131	0	644	686	1	1
SMAD2	ZIC2	0	0	171	332	1	1
SMAD2	C9orf156	165	0	0	165	1	1
SMAD2	EPHB2	0	0	142	201	1	2
SMAD2	COL4A5	0	0	75	197	1	1
SMAD2	TWIST2	0	0	298	314	1	1
SMAD2	FLOT2	0	0	90	152	1	1
SMAD2	BANF1	0	0	193	207	1	1
SMAD2	TBX15	0	0	0	389	1	1
SMAD2	FGF9	0	0	263	426	1	1
SMAD2	CEBPB	0	900	552	954	1	2
SMAD2	SOX1	0	0	242	264	1	1
SMAD2	EVX2	0	0	0	158	1	1
SMAD2	WNT3	0	0	395	445	1	1
SMAD2	PHC3	0	0	149	190	1	1
SMAD2	FGF11	0	0	0	371	1	1
SMAD2	ERCC5	0	0	0	179	1	1
SMAD2	SCRIB	0	0	103	216	1	1
SMAD2	MAP3K10	0	0	118	215	1	1
SMAD2	WWC3	0	0	0	174	1	1
SMAD2	RLN2	0	0	193	193	1	1
SMAD2	RIPK1	0	0	96	158	1	2
SMAD2	SAMD4A	0	0	694	742	1	1
SMAD2	NLRP3	0	0	407	407	1	2
SMAD2	KLC1	0	0	453	478	1	1
SMAD2	REL	0	0	264	301	1	2
SMAD2	HDAC9	0	0	170	194	1	1
SMAD2	BRCA2	270	0	214	463	1	1
SMAD2	ELF3	0	0	141	168	1	1
SMAD2	MYH7	0	0	134	188	1	1
SMAD2	TGFBR3	0	0	600	629	1	1
SMAD2	SMURF1	671	900	633	990	1	1
SMAD2	CDH16	0	0	124	158	1	1
SMAD2	PTGS2	0	0	372	376	1	2
SMAD2	ARID3A	0	0	92	209	1	1
SMAD2	F3	0	0	172	171	1	1
SMAD2	ERBB3	0	0	261	298	1	1
SMAD2	CASP3	0	0	561	592	1	2
SMAD2	ACE	0	0	428	451	1	1
SMAD2	PPM1B	0	0	96	231	1	1
SMAD2	LTBP3	0	0	325	339	1	1
SMAD2	IHH	0	0	340	388	1	1
SMAD2	REN	0	0	419	445	1	1
SMAD2	TNFRSF10B	0	0	137	172	1	2
SMAD2	IL13	0	0	391	390	1	2
SMAD2	VEGFC	0	0	253	252	1	1
SMAD2	CYBB	0	0	324	328	1	2
SMAD2	WTAP	0	0	157	175	1	1
SMAD2	SMARCA1	0	0	430	444	1	1
SMAD2	ENSG00000268643	0	0	0	178	1	1
SMAD2	SLC7A6	0	0	0	303	1	1
SMAD2	SMARCD3	0	0	108	234	1	1
SMAD2	CYP11A1	130	0	150	241	1	1
SMAD2	PTF1A	0	0	180	179	1	1
SMAD2	THBS1	0	0	556	562	1	1
SMAD2	ABCB1	0	0	155	154	1	2
SMAD2	MAPT	270	0	95	311	1	2
SMAD2	BECN1	152	0	294	414	1	2
SMAD2	LRP1	0	0	162	163	1	1
SMAD2	FZD3	0	0	160	175	1	1
SMAD2	ITGA2	0	0	229	228	1	1
SMAD2	OLR1	0	0	127	162	1	2
SMAD2	TLR6	0	0	81	162	1	1
SMAD2	IL2	0	0	394	394	1	1
SMAD2	PIAS1	0	0	481	496	1	1
SMAD2	BCAN	0	0	142	180	1	1
SMAD2	IPO7	0	0	193	366	1	1
SMAD2	FLT4	0	0	166	183	1	1
SMAD2	MAPK11	0	0	160	272	1	1
SMAD2	NCCRP1	0	0	0	188	1	1
SMAD2	DUSP1	0	0	201	218	1	1
SMAD2	FGF23	0	0	129	276	1	1
SMAD2	PPM1A	270	900	563	969	1	1
SMAD2	PTGER3	0	0	153	167	1	1
SMAD2	MLH1	0	0	270	270	1	1
SMAD2	AMH	0	0	390	470	1	1
SMAD2	CDC25A	0	0	266	330	1	1
SMAD2	PSMD2	0	0	291	312	1	1
SMAD2	CTDNEP1	0	0	167	350	1	1
SMAD2	MYH11	0	0	361	366	1	1
SMAD2	CD81	0	0	171	228	1	1
SMAD2	DLX5	0	0	221	246	1	1
SMAD2	FOXC1	0	0	233	300	1	1
SMAD2	KDM6B	270	0	889	919	1	1
SMAD2	FASLG	0	0	246	245	1	1
SMAD2	RHOD	128	0	435	497	1	1
SMAD2	GAS7	0	0	0	180	1	1
SMAD2	SOCS3	0	0	315	325	1	1
SMAD2	ZFP42	0	0	160	181	1	1
SMAD2	MMP24	0	0	69	333	1	1
SMAD2	RXRA	73	0	134	201	1	1
SMAD2	STAT5A	0	0	402	451	1	1
SMAD2	MCM6	0	0	124	198	1	1
SMAD2	FOXN1	0	0	113	173	1	1
SMAD2	ADAM15	0	0	97	268	1	1
SMAD2	DCC	0	0	204	249	1	1
SMAD2	ASCL1	0	0	141	192	1	1
SMAD2	KRAS	0	0	507	579	1	2
SMAD2	ZIC3	0	0	387	402	1	1
SMAD2	DCP1A	0	900	52	903	1	1
SMAD2	FOXD1	0	0	107	167	1	1
SMAD2	ANAPC10	270	0	0	408	1	1
SMAD2	NKX3-2	0	0	157	236	1	1
SMAD2	PTH	0	0	257	256	1	1
SMAD2	HOXC8	0	0	217	317	1	1

Ontologies

ID	Category	Term	Effect	Evidence
GO:0003677	Molecular Function	DNA binding	contributes_to	IDA
GO:0001228	Molecular Function	DNA-binding transcription activator activity, RNA polymerase II-specific	enables	IDA
GO:0001228	Molecular Function	DNA-binding transcription activator activity, RNA polymerase II-specific	enables	ISS
GO:0003700	Molecular Function	DNA-binding transcription factor activity	contributes_to	IDA
GO:0003700	Molecular Function	DNA-binding transcription factor activity	enables	IDA
GO:0000981	Molecular Function	DNA-binding transcription factor activity, RNA polymerase II-specific	enables	IBA
GO:0000981	Molecular Function	DNA-binding transcription factor activity, RNA polymerase II-specific	enables	ISA
GO:0140297	Molecular Function	DNA-binding transcription factor binding	enables	IPI
GO:0070411	Molecular Function	I-SMAD binding	enables	IBA
GO:0070411	Molecular Function	I-SMAD binding	enables	IPI
GO:0070412	Molecular Function	R-SMAD binding	enables	IPI
GO:0000978	Molecular Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	enables	IBA
GO:0000978	Molecular Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	enables	IDA
GO:0061629	Molecular Function	RNA polymerase II-specific DNA-binding transcription factor binding	enables	IEA
GO:0046332	Molecular Function	SMAD binding	enables	IPI
GO:0003682	Molecular Function	chromatin binding	enables	IEA
GO:0000987	Molecular Function	cis-regulatory region sequence-specific DNA binding	enables	IC
GO:0070410	Molecular Function	co-SMAD binding	enables	IPI
GO:0097718	Molecular Function	disordered domain specific binding	enables	IPI
GO:0003690	Molecular Function	double-stranded DNA binding	enables	ISS
GO:0042802	Molecular Function	identical protein binding	enables	IPI
GO:0046872	Molecular Function	metal ion binding	enables	IEA
GO:0019902	Molecular Function	phosphatase binding	enables	IPI
GO:0005515	Molecular Function	protein binding	enables	IPI
GO:0048156	Molecular Function	tau protein binding	enables	ISS
GO:0005160	Molecular Function	transforming growth factor beta receptor binding	enables	IPI
GO:0034713	Molecular Function	type I transforming growth factor beta receptor binding	enables	IPI
GO:0031625	Molecular Function	ubiquitin protein ligase binding	enables	IPI
GO:0006351	Biological Process	DNA-templated transcription	involved_in	NAS
GO:0060395	Biological Process	SMAD protein signal transduction	involved_in	IBA
GO:0060395	Biological Process	SMAD protein signal transduction	acts_upstream_of_or_within	IDA
GO:0060395	Biological Process	SMAD protein signal transduction	involved_in	IDA
GO:0060395	Biological Process	SMAD protein signal transduction	involved_in	IMP
GO:0032924	Biological Process	activin receptor signaling pathway	involved_in	IBA
GO:0032924	Biological Process	activin receptor signaling pathway	involved_in	IMP
GO:0032924	Biological Process	activin receptor signaling pathway	involved_in	NAS
GO:0030325	Biological Process	adrenal gland development	involved_in	IEA
GO:0009653	Biological Process	anatomical structure morphogenesis	involved_in	IBA
GO:0009952	Biological Process	anterior/posterior pattern specification	involved_in	ISS
GO:0003180	Biological Process	aortic valve morphogenesis	involved_in	ISS
GO:0030154	Biological Process	cell differentiation	involved_in	IBA
GO:0045165	Biological Process	cell fate commitment	involved_in	ISS
GO:0003140	Biological Process	determination of left/right asymmetry in lateral mesoderm	involved_in	IMP
GO:0048701	Biological Process	embryonic cranial skeleton morphogenesis	involved_in	IEA
GO:0048617	Biological Process	embryonic foregut morphogenesis	involved_in	IEA
GO:0003203	Biological Process	endocardial cushion morphogenesis	involved_in	ISS
GO:0001706	Biological Process	endoderm formation	involved_in	IEA
GO:0007369	Biological Process	gastrulation	involved_in	TAS
GO:0001701	Biological Process	in utero embryonic development	involved_in	IEA
GO:0030073	Biological Process	insulin secretion	involved_in	IEA
GO:0035556	Biological Process	intracellular signal transduction	involved_in	ISS
GO:0030324	Biological Process	lung development	involved_in	IEA
GO:0001707	Biological Process	mesoderm formation	involved_in	ISS
GO:0045892	Biological Process	negative regulation of DNA-templated transcription	involved_in	IMP
GO:0008285	Biological Process	negative regulation of cell population proliferation	involved_in	IEA
GO:0038092	Biological Process	nodal signaling pathway	involved_in	IMP
GO:0071895	Biological Process	odontoblast differentiation	involved_in	ISS
GO:0035265	Biological Process	organ growth	involved_in	IEA
GO:0031016	Biological Process	pancreas development	involved_in	IEA
GO:0048340	Biological Process	paraxial mesoderm morphogenesis	involved_in	ISS
GO:0060039	Biological Process	pericardium development	involved_in	IEA
GO:0030513	Biological Process	positive regulation of BMP signaling pathway	involved_in	IMP
GO:0045893	Biological Process	positive regulation of DNA-templated transcription	involved_in	IDA
GO:0045893	Biological Process	positive regulation of DNA-templated transcription	involved_in	IMP
GO:0045893	Biological Process	positive regulation of DNA-templated transcription	involved_in	ISS
GO:0010718	Biological Process	positive regulation of epithelial to mesenchymal transition	involved_in	ISS
GO:0010628	Biological Process	positive regulation of gene expression	involved_in	IEA
GO:0045944	Biological Process	positive regulation of transcription by RNA polymerase II	involved_in	IBA
GO:0045944	Biological Process	positive regulation of transcription by RNA polymerase II	involved_in	IDA
GO:0045944	Biological Process	positive regulation of transcription by RNA polymerase II	involved_in	ISS
GO:0009791	Biological Process	post-embryonic development	involved_in	IEA
GO:0031053	Biological Process	primary miRNA processing	involved_in	TAS
GO:0003184	Biological Process	pulmonary valve morphogenesis	involved_in	ISS
GO:0051098	Biological Process	regulation of binding	involved_in	ISS
GO:0017015	Biological Process	regulation of transforming growth factor beta receptor signaling pathway	involved_in	IMP
GO:0070723	Biological Process	response to cholesterol	involved_in	IDA
GO:0009749	Biological Process	response to glucose	involved_in	IEA
GO:0062009	Biological Process	secondary palate development	involved_in	ISS
GO:0023019	Biological Process	signal transduction involved in regulation of gene expression	involved_in	IEA
GO:0007179	Biological Process	transforming growth factor beta receptor signaling pathway	involved_in	IBA
GO:0007179	Biological Process	transforming growth factor beta receptor signaling pathway	involved_in	IDA
GO:0007179	Biological Process	transforming growth factor beta receptor signaling pathway	involved_in	IMP
GO:0001657	Biological Process	ureteric bud development	involved_in	IEA
GO:0007352	Biological Process	zygotic specification of dorsal/ventral axis	involved_in	IMP
GO:0071141	Cellular Component	SMAD protein complex	part_of	IDA
GO:0032444	Cellular Component	activin responsive factor complex	part_of	IDA
GO:0000785	Cellular Component	chromatin	part_of	IDA
GO:0000785	Cellular Component	chromatin	part_of	ISA
GO:0005737	Cellular Component	cytoplasm	located_in	IDA
GO:0005829	Cellular Component	cytosol	located_in	TAS
GO:0071144	Cellular Component	heteromeric SMAD protein complex	part_of	IBA
GO:0071144	Cellular Component	heteromeric SMAD protein complex	part_of	IDA
GO:0071144	Cellular Component	heteromeric SMAD protein complex	part_of	IPI
GO:0005654	Cellular Component	nucleoplasm	located_in	TAS
GO:0005634	Cellular Component	nucleus	located_in	IDA
GO:0032991	Cellular Component	protein-containing complex	part_of	IMP
GO:0005667	Cellular Component	transcription regulator complex	part_of	IDA

Pathways

Name	DB	ID
Signaling by NODAL	Reactome	R-HSA-1181150
Developmental Biology	Reactome	R-HSA-1266738
Signaling by Activin	Reactome	R-HSA-1502540
Signal Transduction	Reactome	R-HSA-162582
Disease	Reactome	R-HSA-1643685
Signaling by TGF-beta Receptor Complex	Reactome	R-HSA-170834
Generic Transcription Pathway	Reactome	R-HSA-212436
Downregulation of TGF-beta receptor signaling	Reactome	R-HSA-2173788
TGF-beta receptor signaling activates SMADs	Reactome	R-HSA-2173789
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer	Reactome	R-HSA-2173793
Downregulation of SMAD2/3:SMAD4 transcriptional activity	Reactome	R-HSA-2173795
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	Reactome	R-HSA-2173796
Loss of Function of SMAD4 in Cancer	Reactome	R-HSA-3304347
Loss of Function of SMAD2/3 in Cancer	Reactome	R-HSA-3304349
Signaling by TGF-beta Receptor Complex in Cancer	Reactome	R-HSA-3304351
SMAD2/3 Phosphorylation Motif Mutants in Cancer	Reactome	R-HSA-3304356
SMAD4 MH2 Domain Mutants in Cancer	Reactome	R-HSA-3311021
SMAD2/3 MH2 Domain Mutants in Cancer	Reactome	R-HSA-3315487
TGFBR1 KD Mutants in Cancer	Reactome	R-HSA-3656532
Loss of Function of TGFBR1 in Cancer	Reactome	R-HSA-3656534
Metabolism of proteins	Reactome	R-HSA-392499
Transcriptional regulation of pluripotent stem cells	Reactome	R-HSA-452723
Diseases of signal transduction by growth factor receptors and second messengers	Reactome	R-HSA-5663202
Deubiquitination	Reactome	R-HSA-5688426
Ub-specific processing proteases	Reactome	R-HSA-5689880
Post-translational protein modification	Reactome	R-HSA-597592
RNA Polymerase II Transcription	Reactome	R-HSA-73857
Gene expression (Transcription)	Reactome	R-HSA-74160
Signaling by TGFB family members	Reactome	R-HSA-9006936
FOXO-mediated transcription	Reactome	R-HSA-9614085
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes	Reactome	R-HSA-9615017
FOXO-mediated transcription of cell cycle genes	Reactome	R-HSA-9617828
Germ layer formation at gastrulation	Reactome	R-HSA-9754189
Gastrulation	Reactome	R-HSA-9758941
Formation of axial mesoderm	Reactome	R-HSA-9796292
Formation of definitive endoderm	Reactome	R-HSA-9823730
Neuroinflammation and glutamatergic signaling (WP5083)	WikiPathways	WP5083_r120385
Integrated cancer pathway (WP1971)	WikiPathways	WP1971_r117762
Hypothesized pathways in pathogenesis of cardiovascular disease (WP3668)	WikiPathways	WP3668_r123393
Canonical and non-canonical TGF-B signaling (WP3874)	WikiPathways	WP3874_r116461
TGF-beta signaling pathway (WP366)	WikiPathways	WP366_r120697
TGF-beta receptor signaling in skeletal dysplasias (WP4816)	WikiPathways	WP4816_r116440
Chromosomal and microsatellite instability in colorectal cancer (WP4216)	WikiPathways	WP4216_r123363
Tgif disruption of Shh signaling (WP3674)	WikiPathways	WP3674_r117841
Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling (WP3850)	WikiPathways	WP3850_r121711
Hepatitis B infection (WP4666)	WikiPathways	WP4666_r123495
Endoderm differentiation (WP2853)	WikiPathways	WP2853_r116557
Inflammatory bowel disease signaling (WP5198)	WikiPathways	WP5198_r123858
Hippo signaling regulation pathways (WP4540)	WikiPathways	WP4540_r120395
Extracellular vesicle-mediated signaling in recipient cells (WP2870)	WikiPathways	WP2870_r106411
Cell cycle (WP179)	WikiPathways	WP179_r122978
Mesodermal commitment pathway (WP2857)	WikiPathways	WP2857_r118395
Epithelial to mesenchymal transition in colorectal cancer (WP4239)	WikiPathways	WP4239_r118997
TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition (WP3859)	WikiPathways	WP3859_r117840
LDLRAD4 and what we know about it (WP4904)	WikiPathways	WP4904_r124593
Progeria-associated lipodystrophy (WP5103)	WikiPathways	WP5103_r119170
TGF-beta receptor signaling (WP560)	WikiPathways	WP560_r117838
Overlap between signal transduction pathways contributing to LMNA laminopathies (WP4879)	WikiPathways	WP4879_r123415
Th17 cell differentiation pathway (WP5130)	WikiPathways	WP5130_r123523
Envelope proteins and their potential roles in EDMD physiopathology (WP4535)	WikiPathways	WP4535_r109210
NRP1-triggered signaling pathways in pancreatic cancer (WP5144)	WikiPathways	WP5144_r120537
Pancreatic adenocarcinoma pathway (WP4263)	WikiPathways	WP4263_r123405
Regucalcin in proximal tubule epithelial kidney cells (WP4838)	WikiPathways	WP4838_r110282
AGE/RAGE pathway (WP2324)	WikiPathways	WP2324_r120674
Neovascularisation processes (WP4331)	WikiPathways	WP4331_r107654

Transcripts

Accession	Version	MolecularType	Name	NCBI	Comments
NM_001135937	3	mRNA	transcript variant 3	NC_000018	Reference
NM_001003652	4	mRNA	transcript variant 2	NC_000018	Reference
NM_005901	6	mRNA	transcript variant 1	NC_000018	Reference
XM_047437508	1	mRNA	transcript variant X3	NC_000018	Reference
XM_017025749	2	mRNA	transcript variant X1	NC_000018	Reference
XM_047437507	1	mRNA	transcript variant X2	NC_000018	Reference