SMAD3

SMAD family member 3

General Information

Name	SMAD family member 3
Alias	mothers against decapentaplegic homolog 3 MAD homolog 3 MAD, mothers against decapentaplegic homolog 3 SMA- and MAD-related protein 3 SMAD, mothers against DPP homolog 3 mad homolog JV15-2 mad protein homolog mothers against DPP homolog 3
Gene_family	SMAD family
organism	Homo sapiens
entrez_id	4088
location	15q22.33
transcript_count	11
exon_count	15

Cross References

Location

by NCBI GRCh38.p14

Summary

Entrez The SMAD family of proteins are a group of intracellular signal transducer proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. The SMAD3 protein functions in the transforming growth factor-beta signaling pathway, and transmits signals from the cell surface to the nucleus, regulating gene activity and cell proliferation. This protein forms a complex with other SMAD proteins and binds DNA, functioning both as a transcription factor and tumor suppressor. Mutations in this gene are associated with aneurysms-osteoarthritis syndrome and Loeys-Dietz Syndrome 3. [provided by RefSeq, May 2022]

Stringdb Mothers against decapentaplegic homolog 3; Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD3/SMAD4 complex, activates transcription. Also can form a SMAD3/SMAD4/JUN/FOS complex at the AP-1/SMAD site to regulate TGF-beta-mediated transcription. Has an inhibitory effect on wound healing probably by modulating both growth and mi [...]

nextProt Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD3/SMAD4 complex, activates transcription. Also can form a SMAD3/SMAD4/JUN/FOS complex at the AP-1/SMAD site to regulate TGF-beta-mediated transcription. Has an inhibitory effect on wound healing probably by modulating both growth and migration of primary keratinocytes and by altering the TGF-mediated chemotaxis of monocytes. This effect on wound healing appears to be hormone-sensitive. Regulator of chondrogenesis and osteogenesis and inhibits early healing of bone fractures. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.

Interactions

NCBI

A	A.Source	B	B.DB	B.Source	Description
SMAD3	BioGRID	PRNP	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	TRIM67	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	N	GeneID	BioGRID	Affinity Capture-Western; Co-localization; Reconstituted Complex
SMAD3	BioGRID	LINC00941	GeneID	BioGRID	Protein-RNA
SMAD3	BioGRID	USP15	GeneID	BioGRID	Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
SMAD3	BioGRID	ZRANB1	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	EZH2	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western
SMAD3	BioGRID	PRKN	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	SMAD4	GeneID	BioGRID	Affinity Capture-Luminescence; Affinity Capture-MS; Affinity Capture-Western; Co-crystal Structure; FRET; PCA; Reconstituted Complex; Two-hybrid
SMAD3	BioGRID	SMAD2	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Phenotypic Enhancement; Two-hybrid
SMAD3	BioGRID	IRF7	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Co-localization; Reconstituted Complex
SMAD3	BioGRID	MECOM	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	TGFBR2	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	TGFBR1	GeneID	BioGRID	Affinity Capture-Western; Biochemical Activity
SMAD3	BioGRID	SUB1	GeneID	BioGRID	Co-fractionation
SMAD3	BioGRID	CTCF	GeneID	BioGRID	Affinity Capture-Western; Co-fractionation; Reconstituted Complex
SMAD3	BioGRID	RBM14	GeneID	BioGRID	Co-fractionation
SMAD3	BioGRID	ANAPC10	GeneID	BioGRID	Affinity Capture-Western; Co-fractionation; Reconstituted Complex
SMAD3	BioGRID	RBX1	GeneID	BioGRID	Affinity Capture-Western; Co-fractionation; Two-hybrid
SMAD3	BioGRID	ZFYVE9	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Co-crystal Structure; Co-fractionation; Reconstituted Complex; Two-hybrid
SMAD3	BioGRID	MTA2	GeneID	BioGRID	Co-fractionation
SMAD3	BioGRID	TRIM33	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Reconstituted Complex
SMAD3	BioGRID	NT5DC3	GeneID	BioGRID	Co-fractionation
SMAD3	BioGRID	SIN3A	GeneID	BioGRID	Co-fractionation; Reconstituted Complex
SMAD3	BioGRID	SNF8	GeneID	BioGRID	Co-fractionation
SMAD3	BioGRID	RIPK1	GeneID	BioGRID	Co-fractionation
SMAD3	BioGRID	RNMT	GeneID	BioGRID	Co-fractionation
SMAD3	BioGRID	CUL1	GeneID	BioGRID	Affinity Capture-Western; Co-fractionation
SMAD3	BioGRID	HMGA2	GeneID	BioGRID	Co-fractionation
SMAD3	BioGRID	XRCC5	GeneID	BioGRID	Co-fractionation
SMAD3	BioGRID	SP1	GeneID	BioGRID	Affinity Capture-Luminescence; Affinity Capture-Western; Co-fractionation; Reconstituted Complex; Two-hybrid
SMAD3	BioGRID	SMARCC2	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Co-fractionation
SMAD3	BioGRID	SMARCC1	GeneID	BioGRID	Affinity Capture-MS; Co-fractionation
SMAD3	BioGRID	SMARCA4	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Co-fractionation
SMAD3	BioGRID	SKP1	GeneID	BioGRID	Co-fractionation
SMAD3	BioGRID	JUND	GeneID	BioGRID	Co-fractionation; Reconstituted Complex
SMAD3	BioGRID	ITGB1	GeneID	BioGRID	Co-fractionation
SMAD3	BioGRID	IGF1R	GeneID	BioGRID	Co-fractionation
SMAD3	BioGRID	HDAC1	GeneID	BioGRID	Co-fractionation; Reconstituted Complex; Two-hybrid
SMAD3	BioGRID	XRCC6	GeneID	BioGRID	Co-fractionation; Two-hybrid
SMAD3	BioGRID	FOXO3	GeneID	BioGRID	Affinity Capture-Western; Co-fractionation; Co-localization
SMAD3	BioGRID	ALKBH2	GeneID	BioGRID	Co-fractionation
SMAD3	BioGRID	NAA15	GeneID	BioGRID	Co-fractionation
SMAD3	BioGRID	OVOL2	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	ARID1B	GeneID	BioGRID	Co-fractionation
SMAD3	BioGRID	RELA	GeneID	BioGRID	Co-fractionation; Two-hybrid
SMAD3	BioGRID	PRKDC	GeneID	BioGRID	Co-fractionation
SMAD3	BioGRID	PARP1	GeneID	BioGRID	Co-fractionation
SMAD3	BioGRID	CTNNB1	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Co-fractionation
SMAD3	BioGRID	CREBBP	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Protein-peptide; Reconstituted Complex; Two-hybrid
SMAD3	BioGRID	CDH1	GeneID	BioGRID	Co-fractionation
SMAD3	BioGRID	DDR1	GeneID	BioGRID	Co-fractionation
SMAD3	BioGRID	ZFHX3	GeneID	BioGRID	Co-fractionation
SMAD3	BioGRID	APP	GeneID	BioGRID	Co-fractionation; Reconstituted Complex
SMAD3	BioGRID	SMURF1	GeneID	BioGRID	Affinity Capture-Western; Two-hybrid
SMAD3	BioGRID	KAT6A	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	TRIM24	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	RARA	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	PPARG	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	USP7	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Two-hybrid
SMAD3	BioGRID	HGS	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	ID1	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	NR4A1	GeneID	BioGRID	Affinity Capture-Western; Two-hybrid
SMAD3	BioGRID	SMURF2	GeneID	BioGRID	Affinity Capture-Luminescence; Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SMAD3	BioGRID	EP300	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SMAD3	BioGRID	EVA1B	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	UGT1A10	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	LSR	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	ZFP69B	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	KCTD16	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	LEMD3	GeneID	BioGRID	Affinity Capture-MS; Reconstituted Complex
SMAD3	BioGRID	FURIN	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	SMAD9	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	TMEM192	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	HINT3	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	LACRT	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	CD6	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	LDLRAD4	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	RIGI	GeneID	BioGRID	Affinity Capture-RNA
SMAD3	BioGRID	PDLIM5	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	STUB1	GeneID	BioGRID	Affinity Capture-Western; FRET; Reconstituted Complex
SMAD3	BioGRID	UCHL1	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	Yap1	GeneID	BioGRID	Reconstituted Complex
SMAD3	BioGRID	CIC	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	DNAJB5	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	JAK1	GeneID	BioGRID	Positive Genetic
SMAD3	BioGRID	TAF2	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	TAF1	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	MED4	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	MED16	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	E6	GeneID	BioGRID	PCA; Two-hybrid
SMAD3	BioGRID	E6	GeneID	BioGRID	PCA; Two-hybrid
SMAD3	BioGRID	PLEKHA4	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	FOXH1	GeneID	BioGRID	Affinity Capture-Western; Protein-peptide; Reconstituted Complex; Two-hybrid
SMAD3	BioGRID	PSMB1	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	NEDD4	GeneID	BioGRID	Affinity Capture-Western; Biochemical Activity; Protein-peptide; Reconstituted Complex; Two-hybrid
SMAD3	BioGRID	SBK3	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	N	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	Zeb2	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	ZNF774	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	CCDC33	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	CCDC198	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	FAM90A1	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	WWP1	GeneID	BioGRID	Affinity Capture-Western; Two-hybrid
SMAD3	BioGRID	USP2	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	DCAF4	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	ATG16L1	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	SUZ12	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	HYAL2	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	TP53	GeneID	BioGRID	Affinity Capture-Western; Co-localization; Reconstituted Complex
SMAD3	BioGRID	WWOX	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	METTL14	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	METTL3	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	RBBP5	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	CPSF7	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	BLZF1	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	PHC2	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	CRX	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	WWP2	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Two-hybrid
SMAD3	BioGRID	RBPMS	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	RELB	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	TLE5	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	MEOX2	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	HIF1A	GeneID	BioGRID	Affinity Capture-Luminescence; Affinity Capture-Western; Co-localization; Phenotypic Enhancement; Reconstituted Complex; Two-hybrid
SMAD3	BioGRID	TRIP4	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	TGFB1	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	MAP2K3	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	PPIE	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	RUNX3	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	TRIM25	GeneID	BioGRID	Affinity Capture-RNA
SMAD3	BioGRID	UCHL5	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	NF2	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	SMAD7	GeneID	BioGRID	Affinity Capture-Western; PCA; Phenotypic Suppression
SMAD3	BioGRID	DNMT3L	GeneID	BioGRID	Reconstituted Complex
SMAD3	BioGRID	NEDD4L	GeneID	BioGRID	Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
SMAD3	BioGRID	SKI	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	KAT2B	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	CDKN1A	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	MAP3K7	GeneID	BioGRID	Co-localization
SMAD3	BioGRID	MAPK8	GeneID	BioGRID	Co-localization
SMAD3	BioGRID	MAX	GeneID	BioGRID	Co-localization; Reconstituted Complex
SMAD3	BioGRID	AKT1	GeneID	BioGRID	Affinity Capture-Western; Co-localization
SMAD3	BioGRID	ETS1	GeneID	BioGRID	Co-localization
SMAD3	BioGRID	EPAS1	GeneID	BioGRID	Co-localization; Two-hybrid
SMAD3	BioGRID	CDK4	GeneID	BioGRID	Biochemical Activity; Co-localization
SMAD3	BioGRID	CDK2	GeneID	BioGRID	Biochemical Activity; Co-localization
SMAD3	BioGRID	CAMK2G	GeneID	BioGRID	Co-localization
SMAD3	BioGRID	DVL1	GeneID	BioGRID	Reconstituted Complex
SMAD3	BioGRID	Pard3	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	Dvl1	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	PARD3	GeneID	BioGRID	Reconstituted Complex
SMAD3	BioGRID	ERBIN	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	Erbin	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	NFIA	GeneID	BioGRID	Reconstituted Complex
SMAD3	BioGRID	NCOA1	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	Dok1	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	RNF111	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	DDX5	GeneID	BioGRID	Reconstituted Complex
SMAD3	BioGRID	XPO6	GeneID	BioGRID	Reconstituted Complex
SMAD3	BioGRID	EIF4B	GeneID	BioGRID	Reconstituted Complex
SMAD3	BioGRID	Sox9	GeneID	BioGRID	Reconstituted Complex
SMAD3	BioGRID	LEF1	GeneID	BioGRID	Affinity Capture-Western; Protein-peptide; Reconstituted Complex
SMAD3	BioGRID	TGFB1I1	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	SKIL	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SMAD3	BioGRID	TEKT4	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	BACH1	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	MAFK	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	FOXM1	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	TRIM62	GeneID	BioGRID	Affinity Capture-Western; Co-localization; Reconstituted Complex
SMAD3	BioGRID	OTUB1	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity
SMAD3	BioGRID	BAG3	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD3	BioGRID	CSNK1D	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity
SMAD3	BioGRID	RUNX1	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	POLY	GeneID	BioGRID	Affinity Capture-Western; Two-hybrid
SMAD3	BioGRID	TSC2	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	FHL3	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	FHL2	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	FHL1	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	Melk	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	LCK	GeneID	BioGRID	Reconstituted Complex
SMAD3	BioGRID	KLF5	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	PIK3CA	GeneID	BioGRID	Reconstituted Complex
SMAD3	BioGRID	SH2D2A	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	DEDD	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SMAD3	BioGRID	SMAD3	GeneID	BioGRID	Affinity Capture-Western; Co-crystal Structure; Reconstituted Complex; Two-hybrid
SMAD3	BioGRID	PARP4	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	RPLP0	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	RPA1	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	EBI3	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	TANK	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	ZEB2	GeneID	BioGRID	Affinity Capture-Western; Two-hybrid
SMAD3	BioGRID	GIT2	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	KMT2B	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	KANSL1	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	TSC22D4	GeneID	BioGRID	Affinity Capture-Western; Two-hybrid
SMAD3	BioGRID	CPTP	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	ZC3H12A	GeneID	BioGRID	Affinity Capture-Western; Two-hybrid
SMAD3	BioGRID	SVEP1	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	ZNF329	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	SAP130	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	VSIR	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	HP	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	RANBP9	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	APOB	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	ANK3	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	MCM3AP	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	SQSTM1	GeneID	BioGRID	Affinity Capture-Western; Two-hybrid
SMAD3	BioGRID	CFLAR	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	CHRD	GeneID	BioGRID	Affinity Capture-Western; Two-hybrid
SMAD3	BioGRID	ZBTB16	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	TLR4	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	TGM2	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	TF	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	SPTBN1	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	SNRNP70	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	TDP2	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	CXXC5	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	SERTAD1	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	SETD2	GeneID	BioGRID	Affinity Capture-Western; Two-hybrid
SMAD3	BioGRID	AATF	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	HEYL	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	GGA1	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	HEY1	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	ZCCHC14	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	NCOA6	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	KDM2A	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	MTF2	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	CORO1A	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	PRDM4	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	DNAJB4	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	TMED1	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	ZMYND11	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	GMEB1	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	ST6GALNAC2	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	CFDP1	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	RCVRN	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	PSMD11	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	PROX1	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	PPP2R1A	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	PLG	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	PLAGL1	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	PLAG1	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	PIN1	GeneID	BioGRID	Affinity Capture-Western; Protein-peptide; Reconstituted Complex; Two-hybrid
SMAD3	BioGRID	PCK2	GeneID	BioGRID	Affinity Capture-Western; Two-hybrid
SMAD3	BioGRID	PCDH1	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	PAPPA	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	NOTCH4	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	MYD88	GeneID	BioGRID	Affinity Capture-Western; Two-hybrid
SMAD3	BioGRID	SMAD1	GeneID	BioGRID	Affinity Capture-MS; Two-hybrid
SMAD3	BioGRID	LBP	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	ISL1	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	HNRNPK	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	HIVEP1	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	CFH	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	FLNA	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	FBLN1	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	CYP11A1	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	CSH2	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	CDC25A	GeneID	BioGRID	Affinity Capture-Western; Two-hybrid
SMAD3	BioGRID	APMAP	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	UBQLN4	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	RIOK2	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	ZNF83	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	RNF31	GeneID	BioGRID	Affinity Capture-Western; Two-hybrid
SMAD3	BioGRID	PPP1R12C	GeneID	BioGRID	Affinity Capture-Western; Two-hybrid
SMAD3	BioGRID	ELAC2	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	CHUK	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	CDK11A	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	FAM83G	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	RPSAP15	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	SMAD5	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	ITGB4	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	IRS1	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	HSPA4	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	C1orf116	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	PJA1	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	SQOR	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	CHD8	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	EPB41L5	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	BUB3	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	PIAS2	GeneID	BioGRID	Reconstituted Complex
SMAD3	BioGRID	DDX3Y	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	SLC25A12	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	YY1	GeneID	BioGRID	Affinity Capture-MS; Reconstituted Complex
SMAD3	BioGRID	VAV2	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	TCP1	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	S100A4	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	RPL4	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	RPL3	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	PTPN6	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	MAPK1	GeneID	BioGRID	Affinity Capture-MS; Biochemical Activity
SMAD3	BioGRID	OPA1	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	DYRK1A	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	DHX8	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	DDX3X	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	ZMIZ1	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	PSPC1	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	DDX4	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	YTHDF2	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	PABPC1	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	RAB11FIP5	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	SIK3	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	DOCK9	GeneID	BioGRID	Affinity Capture-MS; Affinity Capture-Western
SMAD3	BioGRID	LRCH1	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	SNW1	GeneID	BioGRID	Affinity Capture-MS; Phenotypic Enhancement; Reconstituted Complex; Two-hybrid
SMAD3	BioGRID	U2AF2	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	ATXN2L	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	DNAJA2	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	DCAF7	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	NHERF2	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	BRCA1	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	PAX6	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	Smad3	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	CBL	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	FOS	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SMAD3	BioGRID	TCF12	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	JUN	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SMAD3	BioGRID	TRIB3	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	SUV39H1	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	RGCC	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	GSK3B	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	DACH1	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	RUNX2	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	YAP1	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	CDK9	GeneID	BioGRID	Biochemical Activity
SMAD3	BioGRID	CDK8	GeneID	BioGRID	Biochemical Activity
SMAD3	BioGRID	NUP153	GeneID	BioGRID	Reconstituted Complex
SMAD3	BioGRID	USP9X	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	NUP214	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	NFIC	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	HNF4A	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	MRTFA	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	SRY	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	SREBF2	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	PRTN3	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	ACTB	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	ATF3	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	ESR1	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	Rnf111	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	KDM6B	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	ARID1A	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	NCOA3	GeneID	BioGRID	Affinity Capture-MS
SMAD3	BioGRID	VDR	GeneID	BioGRID	Reconstituted Complex; Two-hybrid
SMAD3	BioGRID	KAT2A	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	Sin3a	GeneID	BioGRID	Reconstituted Complex
SMAD3	BioGRID	TOB1	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	HDAC5	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	HDAC4	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	TGIF1	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	SOX9	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	PITX2	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	PITX1	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	MYOCD	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	MED15	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	MED6	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	MED24	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	PIAS4	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SMAD3	BioGRID	ITCH	GeneID	BioGRID	Reconstituted Complex
SMAD3	BioGRID	GRIP1	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	CITED2	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	ZBTB3	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	PRDM16	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	SS18L1	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	HOXC11	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	FLI1	GeneID	BioGRID	Two-hybrid
SMAD3	BioGRID	BPTF	GeneID	BioGRID	Reconstituted Complex
SMAD3	BioGRID	FOXL2	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	BMP7	GeneID	BioGRID	Co-localization
SMAD3	Protein	Functional smad suppressing element 18	None	HPRD
SMAD3	Protein	SAP130	GeneID	HPRD
SMAD3	Protein	EID2	GeneID	HPRD
SMAD3	Protein	ANAPC10	GeneID	HPRD
SMAD3	Protein	HEYL	GeneID	HPRD
SMAD3	Protein	CFDP1	GeneID	HPRD
SMAD3	Protein	MAGI2	GeneID	HPRD
SMAD3	Protein	PPM1A	GeneID	HPRD
SMAD3	Protein	PPP2R1A	GeneID	HPRD
SMAD3	Protein	GMEB1	GeneID	HPRD
SMAD3	Protein	DACH1	GeneID	HPRD
SMAD3	Protein	PLAGL1	GeneID	HPRD
SMAD3	Protein	GSC	GeneID	HPRD
SMAD3	Protein	ZDHHC4	GeneID	HPRD
SMAD3	Protein	RASL12	GeneID	HPRD
SMAD3	Protein	RASD2	GeneID	HPRD
SMAD3	Protein	VSIR	GeneID	HPRD
SMAD3	Protein	MTF2	GeneID	HPRD
SMAD3	Protein	CXXC5	GeneID	HPRD
SMAD3	Protein	SVEP1	GeneID	HPRD
SMAD3	Protein	MED15	GeneID	HPRD
SMAD3	Protein	GGA1	GeneID	HPRD
SMAD3	Protein	EBI3	GeneID	HPRD
SMAD3	Protein	NEDD9	GeneID	HPRD
SMAD3	Protein	ZBTB16	GeneID	HPRD
SMAD3	Protein	CLASRP	GeneID	HPRD
SMAD3	Protein	EIF4ENIF1	GeneID	HPRD
SMAD3	Protein	PRDM4	GeneID	HPRD
SMAD3	Protein	SF3B2	GeneID	HPRD
SMAD3	Protein	ST6GALNAC2	GeneID	HPRD
SMAD3	Protein	RIT1	GeneID	HPRD
SMAD3	Protein	RNF111	GeneID	HPRD
SMAD3	Protein	TOB1	GeneID	HPRD
SMAD3	Protein	PIAS3	GeneID	HPRD
SMAD3	Protein	HSPA4	GeneID	HPRD
SMAD3	Protein	GTF2IRD1	GeneID	HPRD
SMAD3	Protein	SRY	GeneID	HPRD
SMAD3	Protein	ZNF329	GeneID	HPRD
SMAD3	Protein	MYO5B	GeneID	HPRD
SMAD3	Protein	PIAS4	GeneID	HPRD
SMAD3	Protein	SF3A1	GeneID	HPRD
SMAD3	Protein	SMURF1	GeneID	HPRD
SMAD3	Protein	SMURF2	GeneID	HPRD
SMAD3	Protein	RBX1	GeneID	HPRD
SMAD3	Protein	EPAS1	GeneID	HPRD
SMAD3	Protein	KAT2B	GeneID	HPRD
SMAD3	Protein	CSH1	GeneID	HPRD
SMAD3	Protein	TGIF2	GeneID	HPRD
SMAD3	Protein	STUB1	GeneID	HPRD
SMAD3	Protein	ERBIN	GeneID	HPRD
SMAD3	Protein	KMT2B	GeneID	HPRD
SMAD3	Protein	PARD3	GeneID	HPRD
SMAD3	Protein	RAB38	GeneID	HPRD
SMAD3	Protein	STRAP	GeneID	HPRD
SMAD3	Protein	ZEB2	GeneID	HPRD
SMAD3	Protein	KDM2A	GeneID	HPRD
SMAD3	Protein	IL37	GeneID	HPRD
SMAD3	Protein	TMED1	GeneID	HPRD
SMAD3	Protein	NFYC	GeneID	HPRD
SMAD3	Protein	NCOA6	GeneID	HPRD
SMAD3	Protein	JPH3	GeneID	HPRD
SMAD3	Protein	PSMD11	GeneID	HPRD
SMAD3	Protein	HGS	GeneID	HPRD
SMAD3	Protein	CTCF	GeneID	HPRD
SMAD3	Protein	AXIN2	GeneID	HPRD
SMAD3	Protein	NUP153	GeneID	HPRD
SMAD3	Protein	RANBP9	GeneID	HPRD
SMAD3	Protein	AXIN1	GeneID	HPRD
SMAD3	Protein	ZFYVE9	GeneID	HPRD
SMAD3	Protein	PCDH1	GeneID	HPRD
SMAD3	Protein	FOXH1	GeneID	HPRD
SMAD3	Protein	BTRC	GeneID	HPRD
SMAD3	Protein	CDC16	GeneID	HPRD
SMAD3	Protein	SMAD9	GeneID	HPRD
SMAD3	Protein	MCM3AP	GeneID	HPRD
SMAD3	Protein	ATF3	GeneID	HPRD
SMAD3	Protein	CUL1	GeneID	HPRD
SMAD3	Protein	SMAD3	GeneID	HPRD
SMAD3	Protein	SNW1	GeneID	HPRD
SMAD3	Protein	PLAG1	GeneID	HPRD
SMAD3	Protein	HEY1	GeneID	HPRD
SMAD3	Protein	MAPK9	GeneID	HPRD
SMAD3	Protein	KPNB1	GeneID	HPRD
SMAD3	Protein	MDM4	GeneID	HPRD
SMAD3	Protein	EP300	GeneID	HPRD
SMAD3	Protein	FOXO3	GeneID	HPRD
SMAD3	Protein	MAP3K7	GeneID	HPRD
SMAD3	Protein	ZMYM2	GeneID	HPRD
SMAD3	Protein	CAMK2G	GeneID	HPRD
SMAD3	Protein	TP73	GeneID	HPRD
SMAD3	Protein	VDR	GeneID	HPRD
SMAD3	Protein	ESR2	GeneID	HPRD
SMAD3	Protein	SMAD1	GeneID	HPRD
SMAD3	Protein	SQSTM1	GeneID	HPRD
SMAD3	Protein	PEX6	GeneID	HPRD
SMAD3	Protein	SMAD2	GeneID	HPRD
SMAD3	Protein	DVL1	GeneID	HPRD
SMAD3	Protein	DAB2	GeneID	HPRD
SMAD3	Protein	MAPK8	GeneID	HPRD
SMAD3	Protein	SMAD4	GeneID	HPRD
SMAD3	Protein	SMAD4	GeneID	HPRD
SMAD3	Protein	E2F5	GeneID	HPRD
SMAD3	Protein	HMGA2	GeneID	HPRD
SMAD3	Protein	E2F4	GeneID	HPRD
SMAD3	Protein	SREBF2	GeneID	HPRD
SMAD3	Protein	ANK3	GeneID	HPRD
SMAD3	Protein	MAPK14	GeneID	HPRD
SMAD3	Protein	HNF4A	GeneID	HPRD
SMAD3	Protein	RUNX2	GeneID	HPRD
SMAD3	Protein	RUNX3	GeneID	HPRD
SMAD3	Protein	KRT2	GeneID	HPRD
SMAD3	Protein	BRCA2	GeneID	HPRD
SMAD3	Protein	CREBBP	GeneID	HPRD
SMAD3	Protein	RRAS2	GeneID	HPRD
SMAD3	Protein	TFE3	GeneID	HPRD
SMAD3	Protein	AR	GeneID	HPRD
SMAD3	Protein	ARHGEF6	GeneID	HPRD
SMAD3	Protein	FOXO4	GeneID	HPRD
SMAD3	Protein	FLNA	GeneID	HPRD
SMAD3	Protein	ZNF83	GeneID	HPRD
SMAD3	Protein	HIVEP1	GeneID	HPRD
SMAD3	Protein	ZNF8	GeneID	HPRD
SMAD3	Protein	WEE1	GeneID	HPRD
SMAD3	Protein	VIM	GeneID	HPRD
SMAD3	Protein	TP53	GeneID	HPRD
SMAD3	Protein	TSC2	GeneID	HPRD
SMAD3	Protein	TPM3	GeneID	HPRD
SMAD3	Protein	NOTCH1	GeneID	HPRD
SMAD3	Protein	TGM2	GeneID	HPRD
SMAD3	Protein	TGFBR2	GeneID	HPRD
SMAD3	Protein	TGFBR1	GeneID	HPRD
SMAD3	Protein	MYC	GeneID	HPRD
SMAD3	Protein	CEBPB	GeneID	HPRD
SMAD3	Protein	ZEB1	GeneID	HPRD
SMAD3	Protein	SP1	GeneID	HPRD
SMAD3	Protein	SPTBN1	GeneID	HPRD
SMAD3	Protein	SNRNP70	GeneID	HPRD
SMAD3	Protein	DDX5	GeneID	HPRD
SMAD3	Protein	RPLP0	GeneID	HPRD
SMAD3	Protein	RARG	GeneID	HPRD
SMAD3	Protein	PRTN3	GeneID	HPRD
SMAD3	Protein	MAPK1	GeneID	HPRD
SMAD3	Protein	PRKAR1B	GeneID	HPRD
SMAD3	Protein	PRKAR2A	GeneID	HPRD
SMAD3	Protein	PAPPA	GeneID	HPRD
SMAD3	Protein	PAEP	GeneID	HPRD
SMAD3	Protein	PAX8	GeneID	HPRD
SMAD3	Protein	SKIL	GeneID	HPRD
SMAD3	Protein	GLI3	GeneID	HPRD
SMAD3	Protein	MECOM	GeneID	HPRD
SMAD3	Protein	JUND	GeneID	HPRD
SMAD3	Protein	JUNB	GeneID	HPRD
SMAD3	Protein	JUN	GeneID	HPRD
SMAD3	Protein	NOTCH4	GeneID	HPRD
SMAD3	Protein	FOXG1	GeneID	HPRD
SMAD3	Protein	FOS	GeneID	HPRD
SMAD3	Protein	SKI	GeneID	HPRD
SMAD3	Protein	AKT1	GeneID	HPRD
SMAD3	Protein	ETS1	GeneID	HPRD
SMAD3	Protein	MYOD1	GeneID	HPRD
SMAD3	Protein	MBD1	GeneID	HPRD
SMAD3	Protein	MAX	GeneID	HPRD
SMAD3	Protein	YBX1	GeneID	HPRD
SMAD3	Protein	LEF1	GeneID	HPRD
SMAD3	Protein	XRCC6	GeneID	HPRD
SMAD3	Protein	LMNA	GeneID	HPRD
SMAD3	Protein	KRT10	GeneID	HPRD
SMAD3	Protein	NR3C1	GeneID	HPRD
SMAD3	Protein	FOXO1	GeneID	HPRD
SMAD3	Protein	ESR1	GeneID	HPRD
SMAD3	Protein	MEN1	GeneID	HPRD
SMAD3	Protein	EPB41	GeneID	HPRD
SMAD3	Protein	CDK4	GeneID	HPRD
SMAD3	Protein	ATF2	GeneID	HPRD
SMAD3	Protein	CYP11A1	GeneID	HPRD
SMAD3	Protein	RBL1	GeneID	HPRD
SMAD3	Protein	CDK2	GeneID	HPRD
SMAD3	Protein	CDC25A	GeneID	HPRD
SMAD3	Protein	CDC27	GeneID	HPRD
SMAD3	Protein	CTNNB1	GeneID	HPRD
SMAD3	Protein	NUP214	GeneID	HPRD
SMAD3	Protein	BRCA1	GeneID	HPRD
SMAD3	Protein	ACTB	GeneID	HPRD
SMAD3	Protein	PML	GeneID	HPRD
SMAD3	BioGRID	KDM5C	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	CSNK1G2	GeneID	BioGRID	Affinity Capture-Western; Biochemical Activity
SMAD3	BioGRID	STRAP	GeneID	BioGRID	Affinity Capture-Western; Phenotypic Suppression
SMAD3	BioGRID	NEDD9	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SMAD3	BioGRID	NR3C1	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	CEBPD	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	CEBPB	GeneID	BioGRID	Reconstituted Complex
SMAD3	BioGRID	CEBPA	GeneID	BioGRID	Reconstituted Complex
SMAD3	BioGRID	ACVR1B	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	Zfp128	GeneID	BioGRID	Reconstituted Complex
SMAD3	BioGRID	PIAS3	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	TFE3	GeneID	BioGRID	Reconstituted Complex
SMAD3	BioGRID	RBL1	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	PML	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	NFYC	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	MYC	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SMAD3	BioGRID	MEN1	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	JUNB	GeneID	BioGRID	Reconstituted Complex; Two-hybrid
SMAD3	BioGRID	DAB2	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	CDC27	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	BRCA2	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	AR	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SMAD3	BioGRID	CDC16	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	KPNB1	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	E2F4	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	ATF2	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SMAD3	BioGRID	MDM4	GeneID	BioGRID	Reconstituted Complex
SMAD3	BioGRID	TGIF2	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	ZEB1	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	HIPK2	GeneID	BioGRID	Reconstituted Complex
SMAD3	BioGRID	EID2	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	BTRC	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	NOTCH1	GeneID	BioGRID	Affinity Capture-Western; Reconstituted Complex
SMAD3	BioGRID	FOXO4	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	FOXO1	GeneID	BioGRID	Affinity Capture-Western
SMAD3	BioGRID	Rasd2	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD3	BioGRID	Arhgef6	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD3	BioGRID	Rab38	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD3	BioGRID	Rras2	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD3	BioGRID	Wwp2	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD3	BioGRID	Trim35	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD3	BioGRID	Fbxo3	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD3	BioGRID	Arhgef7	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD3	BioGRID	Clasrp	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD3	BioGRID	Ppp2r2d	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD3	BioGRID	Rgs3	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD3	BioGRID	Map2k3	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD3	BioGRID	Wee1	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD3	BioGRID	Sqstm1	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD3	BioGRID	Smad2	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD3	BioGRID	Gsc	GeneID	BioGRID	Affinity Capture-Luminescence
SMAD3	Protein	CREBBP	GeneID	BIND	CBP interacts with Smad3. This interaction was modeled on a demonstrated interaction between mouse CBP and Smad3 from an unspecified species.
SMAD3	Protein	LEF1	GeneID	BIND	Lef1 interacts with Smad3. This interaction was modeled on a demonstrated interaction between mouse Lef1 and Smad3 from an unspecified species.
SMAD3	Protein	FOXH1	GeneID	BIND	The SIM motif of FoxH1 interacts with Smad3. This interaction was modeled on a demonstrated interaction between human FoxH1 and Smad3 from an unspecified species.
SMAD3	Protein	TGFB1I1	GeneID	BIND	ARA55 interacts with Smad3. This interaction was modeled on a demonstrated interaction between human ARA55 and Smad3 from an unspecified species.
SMAD3	Protein	SMAD2	GeneID	BIND	Smad2 interacts with Smad3. This interaction was modeled on a demonstrated interaction between Smad2 from an unspecified species and Smad3 from an unspecified species.
SMAD3	Protein	SMAD4	GeneID	BIND	Smad3 interacts with Smad4. This interaction was modeled on a demonstrated interaction between Smad3 from an unspecified species and Smad4 from an unspecified species.
SMAD3	Protein	NUP214	GeneID	BIND	Smad3 interacts with CAN/Nup214. This interaction was modelled on a demonstrated interaction between Smad3 and CAN/Nup214 whose origins are unknown.
SMAD3	Protein	SF3B2	GeneID	BIND	Smad3 interacts with SF3b2. This interaction is modeled on demonstrated interaction between human Smad3 and mouse SF3b2.
SMAD3	Protein	SMAD4	GeneID	BIND	Smad4 interacts with Smad3.
SMAD3	Protein	SKIL	GeneID	BIND	Smad3 interacts with SnoN. This interaction was modeled on a demonstrated interaction between SnoN from an unspecified source and human Smad3.
SMAD3	Protein	EP300	GeneID	BIND	SMAD3 interacts with EP300 (p300).
SMAD3	Protein	POLY	GeneID	BIND	Hepatits C virus NS3 protein interacts with Smad3.
SMAD3	Protein	POLY	GeneID	BIND	Hepatits C virus core protein interacts with Smad3.
SMAD3	Protein	SMAD2	GeneID	BIND	SMAD3 interacts with SMAD2.
SMAD3	Protein	SMURF2	GeneID	BIND	SMAD3 interacts with SMURF2.
SMAD3	Protein	TGFBR1	GeneID	BIND	T-beta-RI phosphorylates hMAD-3. This interaction was modeled on a demonstrated interaction between T-beta-RI from an unspecified species and human hMAD-3.
SMAD3	Protein	SREBF2	GeneID	BIND	SMAD3 interacts with SREBPF2 (SREBP2).
SMAD3	Protein	TGFBR2	GeneID	BIND	T-beta-RII phosphorylates hMAD-3. This interaction was modeled on a demonstrated interaction between T-beta-RII from an unspecified species and human hMAD-3.
SMAD3	Protein	BRCA2	GeneID	BIND	SMAD3 interacts with BRCA2.
SMAD3	Protein	SKI	GeneID	BIND	c-Ski interacts with Smad3. This interaction was modeled on a demonstrated interaction between Smad3 from an unspecified source and human c-Ski.
SMAD3	Protein	BRCA1	GeneID	BIND	BRCA1 interacts with Smad3.
SMAD3	Protein	None	None	BIND	hMAD-3 forms a complex with TGF-beta-R1 and TGF-beta-R2.
SMAD3	Protein	PML	GeneID	BIND	cPML interacts with Smad3.
SMAD3	Protein	EP300	GeneID	BIND	Smad3 interacts with p300. This interaction was modeled on a demonstrated interaction between Smad3 and p300 from an unspecified sources.
SMAD3	Protein	E1A	GeneID	BIND	E1A interacts with Smad3. This interaction was modeled on a demonstrated interaction between E1A from an unspecified adenovirus and Smad3 from an unspecified source.
SMAD3	Protein	FOXO3	GeneID	BIND	FoxO3 interacts with Smad3.
SMAD3	Protein	FOXO4	GeneID	BIND	FoxO4 interacts with Smad3. This interaction was modelled on a demonstrated interaction between FoxO4 from human and Smad3 from an unspecified species.
SMAD3	Protein	FOXO1	GeneID	BIND	FoxO1 interacts with Smad3. This interaction was modelled on a demonstrated interaction between FoxO1 from an unspecified species and Smad3 from an unspecified species.
SMAD3	Protein	FOXH1	GeneID	BIND	FoxH1 interacts with Smad3. This interaction was modelled on a demonstrated interaction between FoxH1 from an unspecified species and Smad3 from an unspecified species.
SMAD3	Protein	SNW1	GeneID	BIND	SKIP interacts with Smad3. This interaction was modeled on a demonstrated interaction between human SKIP and Smad3 from an unspecified source.
SMAD3	Protein	VDR	GeneID	BIND	VDR interacts with Smad3. This interaction was modeled on a demonstrated interaction between VDR and Smad3 from unspecified sources.
SMAD3	Protein	NEDD9	GeneID	BIND	Smad3 interacts with HEF1.
SMAD3	Protein	PEX6	GeneID	BIND	Smad3 interacts with Pex6. This interaction is modeled on demonstrated interaction between human Smad3 and mouse Pex6.
SMAD3	Protein	EIF4ENIF1	GeneID	BIND	Smad3 interacts with 4-ET. This interaction was modeled on a demonstrated interaction between human Smad3 and mouse 4-ET.
SMAD3	Protein	ZMYM2	GeneID	BIND	Smad3 interacts with ZNF198. This interaction was modeled on a demonstrated interaction between human Smad3 and mouse ZNF198.
SMAD3	Protein	CDK4	GeneID	BIND	CDK4 phosphorylates Smad3 on Thr8, Thr179, Ser204, Ser208 and Ser213. This interaction was modelled on a demonstrated interaction between Smad3 from an unspecified species and mouse CDK4.
SMAD3	Protein	CDK2	GeneID	BIND	CDK2 phosphorylates Smad3 on Thr8, Thr179, Ser204, Ser208 and Ser213. This interaction was modelled on a demonstrated interaction between Smad3 from an unspecified species and human CDK2.
SMAD3	Protein	ANAPC10	GeneID	BIND	Smad3 interacts with APC10.

StringDB

A	B	experiments	database	textmining	combined score	hadb	nhadb
SMAD3	RXRB	0	0	150	191	1	1
SMAD3	CARD11	0	0	146	151	1	1
SMAD3	FOXC1	0	0	200	272	1	1
SMAD3	DLX5	0	0	180	199	1	1
SMAD3	CTDNEP1	0	0	66	272	1	1
SMAD3	MYH11	0	0	507	518	1	1
SMAD3	COL9A1	0	0	174	193	1	1
SMAD3	SAR1B	0	0	0	260	1	1
SMAD3	CDC25A	314	900	269	950	1	1
SMAD3	IL18R1	0	0	358	386	1	1
SMAD3	AMH	0	0	297	387	1	1
SMAD3	MLH1	0	0	181	186	1	1
SMAD3	CDKN2C	0	0	144	176	1	1
SMAD3	PPM1A	270	900	580	968	1	1
SMAD3	DUSP1	0	0	261	277	1	1
SMAD3	FGF23	0	0	165	201	1	1
SMAD3	NCCRP1	0	0	0	188	1	1
SMAD3	MAPK11	0	0	181	289	1	1
SMAD3	FLT4	0	0	166	183	1	1
SMAD3	IPO7	0	0	411	538	1	1
SMAD3	PIAS1	0	0	246	281	1	1
SMAD3	ASH2L	0	0	141	173	1	1
SMAD3	IL2	0	0	460	459	1	1
SMAD3	TLR6	0	0	108	184	1	1
SMAD3	GIT2	131	0	57	150	1	1
SMAD3	ITGA2	0	0	260	260	1	1
SMAD3	ANXA1	0	0	155	185	1	1
SMAD3	MUC4	0	0	173	173	1	1
SMAD3	BECN1	0	0	261	277	1	2
SMAD3	NUAK2	0	0	457	457	1	1
SMAD3	THBS1	0	0	504	504	1	1
SMAD3	SMARCD3	0	0	95	201	1	1
SMAD3	CYP11A1	130	0	99	196	1	1
SMAD3	HOXC8	0	0	208	309	1	1
SMAD3	NKX3-2	0	0	113	197	1	1
SMAD3	PTH	0	0	290	290	1	1
SMAD3	ANAPC10	270	0	749	811	1	1
SMAD3	FOXD1	0	0	134	192	1	1
SMAD3	KRAS	0	0	416	498	1	2
SMAD3	ASCL1	0	0	141	163	1	1
SMAD3	FOXK1	0	0	71	150	1	1
SMAD3	ADAM15	0	0	0	179	1	1
SMAD3	DEPTOR	0	0	174	173	1	2
SMAD3	FOXN1	0	0	112	172	1	1
SMAD3	MCM6	0	0	113	164	1	1
SMAD3	STAT5A	0	0	469	536	1	1
SMAD3	PTPN18	0	900	0	902	1	1
SMAD3	RXRA	0	0	261	298	1	1
SMAD3	MMP24	0	0	81	246	1	1
SMAD3	SOCS3	0	0	337	346	1	1
SMAD3	GAS7	0	0	55	192	1	1
SMAD3	PRKAR1A	0	0	139	190	1	2
SMAD3	KDM6B	270	0	814	864	1	1
SMAD3	FASLG	0	0	241	240	1	1
SMAD3	RIPK1	0	0	95	157	1	2
SMAD3	WWC3	0	0	0	174	1	1
SMAD3	SCRIB	0	0	55	195	1	1
SMAD3	FGF11	0	0	0	250	1	1
SMAD3	WNT3	0	0	322	378	1	1
SMAD3	EVX2	0	0	0	158	1	1
SMAD3	FGF9	0	0	151	235	1	1
SMAD3	CEBPB	486	900	959	997	1	2
SMAD3	NOD2	0	0	206	206	1	2
SMAD3	TBX15	0	0	45	173	1	1
SMAD3	TWIST2	0	0	294	302	1	1
SMAD3	COL4A5	0	0	112	300	1	1
SMAD3	EPHB2	0	0	159	216	1	2
SMAD3	RIN1	0	0	54	295	1	1
SMAD3	ZIC2	0	0	81	170	1	1
SMAD3	DUSP2	0	0	143	179	1	1
SMAD3	INSRR	0	0	0	173	1	1
SMAD3	GSK3B	486	0	370	854	1	2
SMAD3	MRC1	0	0	228	241	1	1
SMAD3	CDC34	0	0	60	374	1	1
SMAD3	SALL4	0	0	123	177	1	1
SMAD3	KRT7	0	0	118	169	1	1
SMAD3	FGF8	0	0	150	305	1	1
SMAD3	CCNG1	0	0	109	220	1	1
SMAD3	RPS27A	270	600	73	710	1	1
SMAD3	GUSB	0	0	150	238	1	1
SMAD3	CDKN2A	0	900	403	938	1	2
SMAD3	ENSG00000268643	0	0	0	178	1	1
SMAD3	RAD21	0	0	134	166	1	1
SMAD3	CYBB	0	0	369	382	1	2
SMAD3	COL6A2	0	0	122	168	1	1
SMAD3	VEGFC	0	0	218	237	1	1
SMAD3	TNFRSF10B	0	0	142	164	1	2
SMAD3	IL13	0	0	573	573	1	2
SMAD3	REN	0	0	402	439	1	1
SMAD3	LTBP3	0	0	308	337	1	1
SMAD3	UBA2	0	0	0	162	1	1
SMAD3	IHH	0	0	324	374	1	1
SMAD3	ACE	0	0	391	408	1	1
SMAD3	ERBB3	0	0	232	271	1	1
SMAD3	CASP3	0	0	517	539	1	2
SMAD3	ARID3A	0	0	58	217	1	1
SMAD3	CDH16	0	0	126	163	1	1
SMAD3	PTGS2	0	0	401	405	1	2
SMAD3	SMURF1	611	900	558	986	1	1
SMAD3	TGFBR3	0	0	556	579	1	1
SMAD3	TUBB2B	0	0	0	188	1	1
SMAD3	EIF4B	270	0	63	286	1	1
SMAD3	MYH7	0	0	167	173	1	1
SMAD3	ELF3	0	0	156	161	1	1
SMAD3	CARD16	0	0	0	188	1	1
SMAD3	BRCA2	270	0	893	919	1	1
SMAD3	HDAC9	0	0	282	303	1	1
SMAD3	REL	0	0	508	511	1	2
SMAD3	NLRP3	0	0	252	252	1	2
SMAD3	SAMD4A	0	0	439	456	1	1
SMAD3	EGLN1	0	0	210	227	1	1
SMAD3	FOXL1	0	0	91	173	1	1
SMAD3	BMPR1A	0	800	510	934	1	1
SMAD3	FZD9	0	0	125	169	1	1
SMAD3	MMP11	0	0	134	338	1	1
SMAD3	NFATC1	0	0	294	309	1	2
SMAD3	E2F5	213	900	539	961	1	1
SMAD3	TERF1	0	0	134	199	1	1
SMAD3	NTRK3	0	0	72	156	1	1
SMAD3	BHLHE41	0	0	413	413	1	1
SMAD3	GAPDHS	0	0	0	209	1	1
SMAD3	COMMD3-BMI1	0	0	273	288	1	1
SMAD3	KIT	0	0	289	303	1	2
SMAD3	NFE2L1	0	0	81	254	1	1
SMAD3	CCNA1	0	0	101	182	1	1
SMAD3	ADAMTS7	0	0	138	192	1	1
SMAD3	RARB	0	0	157	229	1	1
SMAD3	NLK	0	0	147	359	1	1
SMAD3	HOXC11	94	0	55	165	1	1
SMAD3	LDHA	0	0	152	151	1	2
SMAD3	HIST1H4K	0	0	203	203	1	1
SMAD3	MARK2	0	0	153	170	1	1
SMAD3	BUB3	257	0	61	312	1	1
SMAD3	E2F3	0	0	269	285	1	1
SMAD3	CDX2	0	0	698	709	1	1
SMAD3	RORC	0	0	269	269	1	1
SMAD3	PSMC3	0	0	0	155	1	1
SMAD3	TNFRSF9	0	0	150	226	1	1
SMAD3	KAT5	0	0	203	225	1	1
SMAD3	TEAD1	0	0	233	296	1	1
SMAD3	PTPN20A	0	900	0	902	1	1
SMAD3	IL18RAP	0	0	181	181	1	1
SMAD3	IGF2	0	0	292	292	1	1
SMAD3	FGF12	0	0	45	254	1	1
SMAD3	MDM4	270	0	124	356	1	1
SMAD3	ENG	0	0	459	473	1	2
SMAD3	CCL3	0	0	253	252	1	1
SMAD3	CCL22	0	0	180	179	1	1
SMAD3	SOX10	0	0	155	362	1	1
SMAD3	ATP1B4	0	650	0	652	1	1
SMAD3	NR1H4	0	0	445	462	1	1
SMAD3	AREL1	0	0	0	174	1	1
SMAD3	GDF15	0	0	285	377	1	1
SMAD3	FOSL2	0	0	483	512	1	1
SMAD3	SMARCC2	270	0	112	357	1	1
SMAD3	GDF5	0	0	391	469	1	1
SMAD3	WNT10A	0	0	284	301	1	1
SMAD3	FOSB	0	0	456	468	1	1
SMAD3	DMD	0	0	139	273	1	2
SMAD3	IRAK4	0	0	113	192	1	1
SMAD3	FLT3	0	0	140	157	1	2
SMAD3	TNPO1	0	0	97	160	1	1
SMAD3	SNAI1	0	0	988	990	1	1
SMAD3	IL10	0	0	504	504	1	2
SMAD3	PPP3R1	0	0	87	177	1	1
SMAD3	FGFR4	0	0	181	251	1	1
SMAD3	HHEX	0	0	100	153	1	1
SMAD3	AGL	270	0	0	285	1	1
SMAD3	TERT	0	0	324	337	1	2
SMAD3	TET2	0	0	454	454	1	2
SMAD3	NKX2-1	192	0	876	902	1	1
SMAD3	MST1R	0	0	96	158	1	1
SMAD3	HAND2	0	0	134	193	1	1
SMAD3	SPHK1	0	0	255	254	1	2
SMAD3	INHBC	0	0	95	211	1	1
SMAD3	COL4A6	0	0	60	165	1	1
SMAD3	TIMP2	0	0	403	407	1	1
SMAD3	MAP1LC3B	0	0	146	161	1	2
SMAD3	SPHK2	0	0	157	156	1	1
SMAD3	TEAD4	0	0	703	722	1	1
SMAD3	SERPINB5	0	0	122	231	1	1
SMAD3	UBC	0	600	82	663	1	2
SMAD3	CAMK2A	129	0	91	193	1	2
SMAD3	DLX1	0	900	75	911	1	1
SMAD3	UBE3B	0	0	0	194	1	1
SMAD3	SETD2	111	0	74	293	1	1
SMAD3	CDC25B	0	0	95	191	1	1
SMAD3	PRKCA	0	0	278	278	1	1
SMAD3	ACVRL1	0	0	468	545	1	1
SMAD3	ELANE	0	0	168	181	1	1
SMAD3	MMP13	0	0	467	508	1	2
SMAD3	ESRP1	0	0	161	161	1	1
SMAD3	RARS	0	0	628	628	1	1
SMAD3	CCR9	0	0	166	179	1	1
SMAD3	RAG2	0	0	228	341	1	1
SMAD3	FN1	0	0	710	766	1	2
SMAD3	TBP	0	0	233	232	1	1
SMAD3	TBX6	0	0	57	189	1	1
SMAD3	NKX2-3	0	0	166	272	1	2
SMAD3	EOMES	0	0	266	306	1	1
SMAD3	MYOCD	270	0	840	880	1	1
SMAD3	LMNB1	0	0	170	234	1	1
SMAD3	PRL	0	0	218	218	1	1
SMAD3	RGS2	0	0	134	366	1	1
SMAD3	ESR1	462	900	610	978	1	2
SMAD3	MSH2	0	0	194	211	1	1
SMAD3	IFNB1	0	0	241	240	1	1
SMAD3	SMAD7	682	900	868	982	1	1
SMAD3	PDCD1	0	0	193	193	1	2
SMAD3	MAZ	0	0	152	221	1	1
SMAD3	BMP8A	0	0	146	256	1	1
SMAD3	LGR5	0	0	212	225	1	1
SMAD3	PAPSS2	0	0	96	160	1	1
SMAD3	INHA	0	0	235	334	1	1
SMAD3	KLF11	0	0	809	829	1	1
SMAD3	IRF1	0	0	294	294	1	2
SMAD3	MYBL2	0	0	168	204	1	1
SMAD3	ELN	0	0	468	476	1	1
SMAD3	SLC22A5	0	0	181	194	1	1
SMAD3	YAP1	270	800	505	955	1	2
SMAD3	OTX2	0	0	142	157	1	1
SMAD3	CXCR3	0	0	186	199	1	1
SMAD3	TNF	0	0	595	610	1	2
SMAD3	MSX1	0	0	217	301	1	1
SMAD3	RNF4	0	0	124	225	1	1
SMAD3	XYLB	0	0	0	171	1	1
SMAD3	NFYC	270	0	448	589	1	1
SMAD3	ITK	0	0	108	169	1	1
SMAD3	KRT14	0	0	203	203	1	1
SMAD3	NT5E	0	0	204	235	1	1
SMAD3	MMP25	0	0	66	200	1	1
SMAD3	MEF2C	0	900	397	941	1	1
SMAD3	SIN3A	270	900	243	957	1	1
SMAD3	HOXA3	0	0	81	244	1	1
SMAD3	ANKRD1	0	0	323	334	1	1
SMAD3	NR4A2	0	0	233	232	1	1
SMAD3	TRAP1	0	0	0	212	1	2
SMAD3	KDM3A	0	0	144	215	1	1
SMAD3	VDR	486	900	843	992	1	2
SMAD3	WISP1	0	0	218	244	1	1
SMAD3	ASCC1	0	0	0	174	1	1
SMAD3	PTGFR	0	0	321	332	1	1
SMAD3	MMP3	0	0	390	437	1	1
SMAD3	PIAS2	270	0	164	404	1	1
SMAD3	RGS3	0	0	104	179	1	1
SMAD3	ERCC3	0	0	0	162	1	1
SMAD3	DDX17	0	0	307	322	1	1
SMAD3	SNAI3	0	0	193	230	1	1
SMAD3	ZNF512B	0	0	74	151	1	1
SMAD3	IKZF4	0	0	265	284	1	1
SMAD3	TFAP2C	0	0	218	218	1	1
SMAD3	NFAT5	0	0	229	306	1	1
SMAD3	PDGFC	0	0	244	266	1	1
SMAD3	PPP1R15A	0	0	155	198	1	2
SMAD3	RBBP7	0	900	60	910	1	1
SMAD3	PAX3	0	0	241	240	1	1
SMAD3	ITCH	270	0	228	524	1	1
SMAD3	EEF2	0	0	90	159	1	2
SMAD3	RPS6KA2	0	0	162	161	1	1
SMAD3	IL5	0	0	335	335	1	1
SMAD3	IL1R2	0	0	156	163	1	1
SMAD3	AGT	0	0	128	442	1	1
SMAD3	TFRC	0	0	140	158	1	1
SMAD3	LAMC1	0	0	139	187	1	1
SMAD3	TFAP2A	0	0	183	183	1	1
SMAD3	AZIN1	0	0	170	188	1	1
SMAD3	CCND2	0	0	345	374	1	1
SMAD3	NFKB2	0	0	218	303	1	1
SMAD3	TMPRSS2	0	0	146	159	1	1
SMAD3	TNFAIP3	0	0	165	165	1	2
SMAD3	GCG	0	0	185	185	1	1
SMAD3	THRSP	0	0	75	174	1	1
SMAD3	ZNF451	0	0	150	208	1	1
SMAD3	FHL3	270	0	0	276	1	1
SMAD3	MMP8	0	0	231	309	1	1
SMAD3	PROX1	131	0	117	200	1	1
SMAD3	HECW1	0	0	0	174	1	1
SMAD3	SCN4A	0	0	0	627	1	1
SMAD3	FERMT1	0	0	113	155	1	1
SMAD3	RETN	0	0	139	158	1	1
SMAD3	CDH5	0	0	310	321	1	1
SMAD3	ATF3	486	900	946	997	1	2
SMAD3	PARD6A	0	0	74	156	1	1
SMAD3	IRF7	270	900	839	987	1	1
SMAD3	TBX18	0	0	117	236	1	1
SMAD3	FOXL2	270	0	950	964	1	1
SMAD3	MMP27	0	0	0	267	1	1
SMAD3	PLOD2	0	0	170	188	1	1
SMAD3	MERTK	0	0	138	197	1	1
SMAD3	C1orf116	257	0	0	256	1	1
SMAD3	ARNTL	0	0	141	177	1	1
SMAD3	THBS2	0	0	203	269	1	1
SMAD3	RPS6KB1	0	0	380	406	1	2
SMAD3	AGTR1	0	0	358	368	1	1
SMAD3	REM1	0	0	0	324	1	1
SMAD3	MUC1	0	0	180	179	1	1
SMAD3	PGR	0	0	256	277	1	1
SMAD3	HIST1H4B	0	0	203	203	1	1
SMAD3	CDK1	0	0	298	328	1	2
SMAD3	NCOR1	0	900	861	985	1	1
SMAD3	SERPINE1	0	900	682	971	1	1
SMAD3	AHR	0	0	467	467	1	2
SMAD3	IDUA	0	0	0	158	1	1
SMAD3	SMTN	0	0	194	233	1	1
SMAD3	NTRK1	0	0	235	304	1	1
SMAD3	PRMT8	0	0	0	173	1	1
SMAD3	CBL	270	0	143	364	1	1
SMAD3	SGK1	0	0	243	272	1	2
SMAD3	IRS1	131	0	272	362	1	2
SMAD3	LOX	0	0	422	438	1	2
SMAD3	EGR2	0	0	209	229	1	1
SMAD3	SERPINE2	0	0	112	474	1	1
SMAD3	FOXC2	0	0	278	326	1	1
SMAD3	ABCG2	0	0	155	154	1	1
SMAD3	DENND1B	0	0	391	390	1	1
SMAD3	GREM2	0	0	113	211	1	1
SMAD3	WNT8B	0	0	218	248	1	1
SMAD3	DVL2	270	0	551	718	1	2
SMAD3	HERC3	0	0	0	193	1	1
SMAD3	HOXB7	0	0	167	299	1	1
SMAD3	CD274	0	0	283	282	1	2
SMAD3	SREBF2	270	0	195	400	1	1
SMAD3	HDAC7	0	0	220	267	1	1
SMAD3	RCC1	0	0	120	181	1	1
SMAD3	AHNAK	0	0	108	238	1	1
SMAD3	SAP30	0	900	73	907	1	1
SMAD3	EPHA1	0	0	95	157	1	1
SMAD3	LIN28A	0	0	202	268	1	1
SMAD3	CTLA4	0	0	455	455	1	2
SMAD3	RRAS2	128	0	0	174	1	1
SMAD3	DDIT4	0	0	150	198	1	2
SMAD3	TOB2	0	0	90	282	1	1
SMAD3	HPRT1	0	0	209	209	1	1
SMAD3	FGF16	0	0	0	250	1	1
SMAD3	SPRY1	0	0	234	250	1	1
SMAD3	PTPN2	0	900	55	904	1	2
SMAD3	MYB	0	0	261	293	1	1
SMAD3	BCL2	0	0	143	187	1	2
SMAD3	SMAD6	0	800	700	866	1	1
SMAD3	FOXA2	0	0	462	519	1	1
SMAD3	ZFYVE9	972	900	984	999	1	1
SMAD3	RASA1	0	0	123	259	1	1
SMAD3	ADAMTS3	0	0	218	231	1	1
SMAD3	MECOM	486	0	854	923	1	1
SMAD3	BMPR2	0	800	632	945	1	1
SMAD3	MAGI2	213	0	108	374	1	1
SMAD3	HGF	0	0	459	467	1	2
SMAD3	POU5F1	270	0	904	950	1	2
SMAD3	MCM7	0	0	150	194	1	1
SMAD3	WNT10B	0	0	287	304	1	1
SMAD3	MKL2	0	0	466	467	1	1
SMAD3	HPGD	0	0	143	156	1	1
SMAD3	DDX5	678	0	733	913	1	1
SMAD3	CAT	0	0	325	329	1	2
SMAD3	GFI1	0	0	150	190	1	1
SMAD3	KLC2	0	0	0	410	1	1
SMAD3	TAL1	0	0	181	181	1	1
SMAD3	PDPK1	0	0	140	163	1	2
SMAD3	DUSP6	0	0	135	220	1	1
SMAD3	EPB41	213	0	46	219	1	1
SMAD3	HMOX1	0	0	341	341	1	2
SMAD3	TCHP	0	0	282	282	1	1
SMAD3	SEC13	0	0	0	152	1	1
SMAD3	DNMT3L	270	0	81	300	1	1
SMAD3	LRRK1	0	0	67	167	1	1
SMAD3	LIN28B	0	0	118	170	1	1
SMAD3	NRG1	0	0	142	157	1	2
SMAD3	HAS2	0	0	246	245	1	1
SMAD3	PTPN7	0	900	0	902	1	1
SMAD3	NFATC2	0	0	834	836	1	1
SMAD3	CDHR3	0	0	235	247	1	1
SMAD3	PIAS4	486	900	901	994	1	1
SMAD3	ELK4	0	0	176	203	1	1
SMAD3	RASSF1	0	0	135	151	1	1
SMAD3	MMP12	0	0	244	262	1	1
SMAD3	MITF	0	0	203	203	1	2
SMAD3	JAK1	189	0	334	479	1	2
SMAD3	JPH1	270	0	0	270	1	1
SMAD3	MSX2	0	0	261	337	1	1
SMAD3	F2R	0	0	139	158	1	1
SMAD3	HACE1	0	0	0	184	1	1
SMAD3	AES	199	0	0	223	1	1
SMAD3	RBX1	270	800	125	861	1	1
SMAD3	LGALS9C	0	0	0	166	1	1
SMAD3	TSC2	270	0	217	407	1	2
SMAD3	HECTD1	0	0	0	192	1	1
SMAD3	RB1	0	0	210	267	1	2
SMAD3	CTCF	462	0	300	626	1	1
SMAD3	STK3	0	0	0	220	1	1
SMAD3	LAMA3	0	0	96	169	1	1
SMAD3	CDKN1B	0	900	420	940	1	2
SMAD3	GPC3	0	0	137	255	1	1
SMAD3	NUP214	270	900	445	956	1	1
SMAD3	CREB5	0	0	101	174	1	1
SMAD3	USP2	270	0	66	301	1	1
SMAD3	ZFPM2	0	0	184	216	1	1
SMAD3	CRIP2	0	0	95	192	1	1
SMAD3	PCSK9	0	0	182	181	1	1
SMAD3	LIFR	0	0	171	171	1	1
SMAD3	KDM6A	0	0	153	167	1	1
SMAD3	METTL3	270	0	456	586	1	2
SMAD3	ADAM12	0	0	207	272	1	1
SMAD3	SRC	0	0	502	577	1	2
SMAD3	ACTL6A	0	0	59	152	1	1
SMAD3	STAMBP	0	0	418	418	1	1
SMAD3	MEOX1	0	0	117	173	1	1
SMAD3	HP	111	0	95	174	1	1
SMAD3	C10orf54	72	0	72	163	1	1
SMAD3	SMURF2	888	900	937	999	1	1
SMAD3	EPHB3	0	0	107	168	1	1
SMAD3	SMARCC1	270	0	151	385	1	1
SMAD3	MKL1	270	0	957	967	1	1
SMAD3	CIB1	0	0	107	257	1	1
SMAD3	LGALS3	0	0	292	328	1	2
SMAD3	FBXW11	0	0	138	192	1	1
SMAD3	TNFRSF18	0	0	263	263	1	1
SMAD3	FLT1	0	0	244	259	1	1
SMAD3	EIF2AK3	0	0	268	268	1	2
SMAD3	WWP2	676	0	282	802	1	1
SMAD3	LRRC7	0	0	0	162	1	1
SMAD3	STAT6	0	0	529	542	1	1
SMAD3	TCF12	270	0	225	438	1	1
SMAD3	ID2	0	0	525	600	1	1
SMAD3	WWOX	486	0	183	572	1	1
SMAD3	CCNG2	270	0	126	362	1	1
SMAD3	IL11	0	0	324	323	1	1
SMAD3	CDC16	270	0	54	288	1	1
SMAD3	CHRD	111	0	265	570	1	1
SMAD3	GSK3A	0	0	75	207	1	1
SMAD3	ITGB6	0	0	270	286	1	1
SMAD3	BIRC5	0	0	125	162	1	2
SMAD3	SIRT4	0	0	209	241	1	1
SMAD3	FGF3	0	0	82	250	1	1
SMAD3	LGALS9B	0	0	0	166	1	1
SMAD3	IPO8	270	0	526	716	1	1
SMAD3	RHOC	0	0	180	270	1	1
SMAD3	ZC3H3	0	0	137	248	1	1
SMAD3	CXCL10	0	0	265	265	1	2
SMAD3	NR1I2	0	0	134	169	1	1
SMAD3	IGF2R	0	0	150	168	1	1
SMAD3	MAFK	270	0	125	354	1	1
SMAD3	CCNE2	0	0	150	225	1	1
SMAD3	MAP3K1	0	0	261	292	1	1
SMAD3	IL6ST	0	0	181	204	1	1
SMAD3	TRIM10	0	0	95	187	1	1
SMAD3	SLIT3	0	0	170	184	1	1
SMAD3	TLR9	0	0	193	207	1	2
SMAD3	FOXF2	0	0	60	179	1	1
SMAD3	HMGA2	213	900	760	981	1	1
SMAD3	ARG2	0	0	184	183	1	1
SMAD3	ERBB2	0	0	550	583	1	2
SMAD3	TRIM2	0	0	0	214	1	1
SMAD3	IRF3	0	0	213	213	1	2
SMAD3	S100A2	0	0	701	701	1	1
SMAD3	KCNJ1	0	0	63	162	1	1
SMAD3	FANCD2	0	0	222	222	1	1
SMAD3	AKT1	632	0	988	996	1	2
SMAD3	TGFB2	0	900	739	978	1	1
SMAD3	CAPN1	0	0	136	159	1	2
SMAD3	UBE3A	0	0	160	293	1	1
SMAD3	SLIT2	0	0	141	161	1	1
SMAD3	PPARG	270	0	722	794	1	2
SMAD3	TEAD2	0	0	193	243	1	1
SMAD3	MKI67	0	0	96	253	1	2
SMAD3	PRDM16	270	0	744	811	1	1
SMAD3	PTHLH	0	0	400	416	1	1
SMAD3	FOXA1	270	0	286	513	1	1
SMAD3	CD4	0	0	556	559	1	2
SMAD3	ATF4	0	0	180	307	1	2
SMAD3	HOXA10	0	0	136	192	1	1
SMAD3	ATF1	0	0	75	169	1	1
SMAD3	FGFR1	0	0	324	382	1	1
SMAD3	ACE2	0	0	195	216	1	2
SMAD3	ATF6	0	0	154	153	1	2
SMAD3	LRCH1	131	0	0	165	1	1
SMAD3	COL1A2	0	0	609	627	1	1
SMAD3	RXFP1	0	0	145	182	1	1
SMAD3	IKBKB	0	0	294	342	1	2
SMAD3	COL6A1	0	0	194	230	1	1
SMAD3	KLF4	0	0	603	662	1	2
SMAD3	SATB1	0	0	218	235	1	1
SMAD3	PCBP4	0	650	0	650	1	1
SMAD3	FMOD	0	0	249	278	1	1
SMAD3	XIAP	0	0	272	287	1	2
SMAD3	CEBPG	0	0	56	282	1	1
SMAD3	PPP2R4	0	0	270	270	1	1
SMAD3	RUNX2	675	900	986	999	1	2
SMAD3	MAFB	0	0	155	214	1	1
SMAD3	RGCC	270	0	899	923	1	1
SMAD3	UBE3C	0	0	0	193	1	1
SMAD3	DVL3	0	0	137	289	1	1
SMAD3	ZNF165	0	0	457	472	1	1
SMAD3	PLCG1	0	0	142	189	1	1
SMAD3	BATF	0	0	294	309	1	1
SMAD3	MAPK12	0	0	150	219	1	1
SMAD3	KL	0	0	261	277	1	2
SMAD3	MAML1	0	0	213	223	1	1
SMAD3	SERPINA1	0	0	123	226	1	2
SMAD3	SEPHS1	0	0	43	177	1	1
SMAD3	NR2F2	0	0	206	252	1	1
SMAD3	KPNB1	270	900	74	929	1	1
SMAD3	CD109	0	0	142	178	1	1
SMAD3	IL10RA	0	0	166	165	1	1
SMAD3	DLL4	0	0	260	276	1	1
SMAD3	KPNA6	0	0	66	177	1	1
SMAD3	BCL2L11	0	900	360	933	1	2
SMAD3	WDR5	0	0	158	177	1	1
SMAD3	MAP2K3	129	0	258	372	1	1
SMAD3	SLC33A1	0	0	0	177	1	1
SMAD3	POLDIP2	0	0	166	165	1	1
SMAD3	HSPA1A	0	0	116	287	1	1
SMAD3	SRF	0	0	457	485	1	1
SMAD3	ORMDL3	0	0	464	463	1	2
SMAD3	TNFSF10	0	0	156	155	1	2
SMAD3	CAV1	0	900	436	943	1	2
SMAD3	DTX1	0	0	102	150	1	1
SMAD3	CASP1	117	650	357	817	1	2
SMAD3	DEDD	270	0	112	324	1	1
SMAD3	AKT1S1	0	0	140	171	1	1
SMAD3	PLAT	0	0	202	238	1	1
SMAD3	SLC16A3	270	0	73	294	1	1
SMAD3	CHEK1	0	0	206	206	1	2
SMAD3	MMP2	0	0	556	572	1	2
SMAD3	CREB3	0	0	400	400	1	1
SMAD3	MAT2A	0	0	217	270	1	1
SMAD3	IGF2BP3	0	0	112	327	1	1
SMAD3	ZBTB17	0	900	88	907	1	1
SMAD3	RIPK2	0	0	95	161	1	2
SMAD3	CRK	0	0	108	174	1	1
SMAD3	TRIM3	0	0	0	214	1	1
SMAD3	TCF7	0	0	261	389	1	1
SMAD3	TOB1	462	0	330	704	1	1
SMAD3	ANGPT2	0	0	180	197	1	1
SMAD3	CD8A	0	0	452	452	1	1
SMAD3	ARID1B	0	0	123	150	1	1
SMAD3	DLL1	0	0	261	277	1	1
SMAD3	IGFBP3	0	0	260	282	1	2
SMAD3	LRRC32	0	0	324	335	1	1
SMAD3	PNMT	0	0	0	181	1	1
SMAD3	CSNK1A1	0	0	457	480	1	1
SMAD3	SHH	0	0	396	440	1	2
SMAD3	LAMB1	0	0	129	175	1	1
SMAD3	CD69	0	0	181	195	1	1
SMAD3	MED12	0	0	291	308	1	1
SMAD3	FZD6	0	0	150	210	1	1
SMAD3	CCR5	0	0	195	208	1	1
SMAD3	IL37	462	800	988	998	1	1
SMAD3	IL17RA	0	0	134	150	1	1
SMAD3	CCRL2	0	0	212	225	1	1
SMAD3	YWHAE	0	0	108	150	1	1
SMAD3	VCP	0	0	90	181	1	2
SMAD3	LCK	270	0	448	609	1	1
SMAD3	HIVEP3	0	0	133	155	1	1
SMAD3	NKX2-2	0	0	82	163	1	1
SMAD3	TLE4	0	0	134	172	1	1
SMAD3	TICAM1	0	0	48	168	1	2
SMAD3	IL22	0	0	217	217	1	1
SMAD3	MYH9	0	0	161	191	1	1
SMAD3	SIRT7	0	0	243	274	1	2
SMAD3	ENSG00000258724	0	0	105	151	1	1
SMAD3	ZEB1	270	0	980	986	1	2
SMAD3	CD24	0	0	261	261	1	2
SMAD3	MXI1	0	0	95	191	1	1
SMAD3	LOXL4	0	0	147	183	1	1
SMAD3	FOXD3	0	0	136	196	1	1
SMAD3	PBX1	0	0	155	318	1	1
SMAD3	LTBP2	0	0	315	354	1	1
SMAD3	STK4	0	0	95	261	1	1
SMAD3	ESR2	213	0	260	410	1	1
SMAD3	TPM1	0	0	171	171	1	1
SMAD3	VEPH1	0	0	155	154	1	1
SMAD3	PIWIL1	0	0	134	152	1	1
SMAD3	KDM1A	0	0	253	302	1	2
SMAD3	KLRK1	0	0	217	230	1	1
SMAD3	FGF4	0	0	136	294	1	1
SMAD3	CXCL12	0	0	390	390	1	2
SMAD3	TCF7L1	0	0	186	310	1	1
SMAD3	ZPBP2	0	0	271	271	1	1
SMAD3	NKRF	0	0	161	182	1	1
SMAD3	INSR	0	0	175	288	1	1
SMAD3	HSPA8	0	900	127	918	1	2
SMAD3	GSR	0	0	134	152	1	1
SMAD3	ETV4	0	0	451	480	1	1
SMAD3	EPCAM	0	0	283	291	1	2
SMAD3	GDF10	0	0	292	383	1	1
SMAD3	ELFN1	0	0	0	208	1	1
SMAD3	RHOA	0	0	507	552	1	2
SMAD3	PARP1	0	600	354	730	1	2
SMAD3	B2M	0	0	171	183	1	1
SMAD3	KEAP1	0	300	235	453	1	2
SMAD3	PAX5	0	0	209	261	1	1
SMAD3	ROS1	0	0	0	204	1	1
SMAD3	PROM1	0	0	322	321	1	2
SMAD3	CSNK1E	0	0	63	239	1	1
SMAD3	SIRT3	0	0	294	396	1	2
SMAD3	ANGPT1	0	0	218	418	1	1
SMAD3	INHBE	0	0	125	238	1	1
SMAD3	MCM5	0	0	108	174	1	1
SMAD3	PBX3	0	0	0	196	1	1
SMAD3	HIST1H4J	0	0	203	203	1	1
SMAD3	GLI3	213	0	310	459	1	1
SMAD3	PDGFD	0	0	172	171	1	1
SMAD3	KHSRP	0	0	134	158	1	1
SMAD3	F2RL2	0	0	0	154	1	1
SMAD3	FCGR2B	0	0	285	285	1	1
SMAD3	HOXB1	0	0	86	197	1	1
SMAD3	INS	0	0	503	540	1	2
SMAD3	GAS6	0	0	103	153	1	1
SMAD3	ACTB	270	0	610	737	1	2
SMAD3	FOXG1	213	900	432	957	1	1
SMAD3	ADAMTS5	0	0	290	302	1	1
SMAD3	TLE1	0	0	113	152	1	1
SMAD3	CD40	0	0	362	362	1	2
SMAD3	WNT6	0	0	253	270	1	1
SMAD3	DNMT1	0	0	535	545	1	2
SMAD3	STUB1	270	800	677	948	1	2
SMAD3	NEUROD1	0	0	181	181	1	1
SMAD3	CEBPA	270	0	524	645	1	1
SMAD3	SETD1A	0	0	117	161	1	1
SMAD3	PKNOX2	0	0	0	161	1	1
SMAD3	SUV39H1	270	0	182	387	1	1
SMAD3	TFEB	0	0	454	454	1	2
SMAD3	FOSL1	0	0	308	342	1	1
SMAD3	IL3	0	0	181	181	1	1
SMAD3	PAX8	213	0	878	902	1	1
SMAD3	SETDB1	0	0	867	868	1	1
SMAD3	ANKRD2	0	0	306	317	1	1
SMAD3	SP7	0	0	294	355	1	1
SMAD3	HPGDS	0	0	523	523	1	1
SMAD3	FBXW7	0	0	226	225	1	2
SMAD3	MFAP5	0	0	322	336	1	1
SMAD3	DSPP	0	0	235	235	1	1
SMAD3	HERC4	0	0	0	193	1	1
SMAD3	DCAF7	257	0	0	256	1	1
SMAD3	FAP	0	0	116	150	1	2
SMAD3	ITGB1	0	0	324	368	1	1
SMAD3	KAT2A	270	900	150	940	1	1
SMAD3	HSPG2	0	0	157	195	1	1
SMAD3	CDK19	0	0	81	283	1	1
SMAD3	DCLK1	0	0	128	166	1	1
SMAD3	XPO7	0	0	61	213	1	1
SMAD3	UBAP2	0	0	0	160	1	1
SMAD3	CASP8	0	0	293	293	1	2
SMAD3	CD276	0	0	180	210	1	1
SMAD3	TRIM62	270	0	234	435	1	1
SMAD3	MYLK	0	0	413	438	1	1
SMAD3	CNN2	0	0	59	165	1	1
SMAD3	PKNOX1	0	0	142	285	1	1
SMAD3	ZMIZ1	270	0	450	589	1	1
SMAD3	FBLN1	131	0	102	221	1	1
SMAD3	SVEP1	130	0	0	163	1	1
SMAD3	NOTCH3	0	0	341	401	1	1
SMAD3	IL9	0	0	315	415	1	1
SMAD3	PBX2	0	0	71	238	1	1
SMAD3	FGF17	0	0	59	231	1	1
SMAD3	ADAMTS10	0	0	167	181	1	1
SMAD3	RYR1	0	0	134	152	1	2
SMAD3	BMP7	273	0	603	770	1	1
SMAD3	PLG	131	0	415	491	1	1
SMAD3	KLF12	0	0	193	214	1	1
SMAD3	FRK	0	0	0	186	1	1
SMAD3	LEFTY2	0	0	217	350	1	1
SMAD3	ZEB2	692	0	720	916	1	1
SMAD3	FZD8	0	0	218	262	1	1
SMAD3	HDAC8	0	0	134	159	1	1
SMAD3	KMT2B	66	0	150	185	1	1
SMAD3	CDK6	0	0	358	370	1	2
SMAD3	HIST1H4E	0	0	203	203	1	1
SMAD3	GLI2	270	0	404	566	1	2
SMAD3	MAPKAPK2	0	0	150	171	1	1
SMAD3	BMP10	0	0	235	333	1	1
SMAD3	ABCA1	0	0	157	156	1	2
SMAD3	TEAD3	0	0	702	727	1	1
SMAD3	SUZ12	42	0	210	231	1	1
SMAD3	RHOB	0	0	468	512	1	1
SMAD3	CCL4	0	0	214	214	1	1
SMAD3	IL1A	0	0	344	343	1	1
SMAD3	CEACAM1	0	0	129	164	1	1
SMAD3	H2AFX	0	0	170	169	1	1
SMAD3	LGALS4	0	0	474	488	1	1
SMAD3	NFIL3	0	0	202	220	1	1
SMAD3	TSC22D1	0	0	246	321	1	1
SMAD3	DLL3	0	0	184	201	1	1
SMAD3	NR3C2	0	0	139	193	1	1
SMAD3	DPP4	0	0	217	250	1	1
SMAD3	NR3C1	486	900	323	963	1	1
SMAD3	PRF1	0	0	230	229	1	1
SMAD3	IL2RG	0	0	133	154	1	1
SMAD3	FKBP1A	0	900	294	926	1	2
SMAD3	PTGER4	0	0	206	219	1	1
SMAD3	PDGFA	0	0	267	267	1	1
SMAD3	CISH	0	0	246	257	1	1
SMAD3	CSK	0	0	122	182	1	1
SMAD3	FLG	0	0	154	174	1	1
SMAD3	CTGF	0	0	730	763	1	1
SMAD3	PXN	0	0	358	389	1	1
SMAD3	HIST2H3PS2	0	0	407	419	1	1
SMAD3	NFIC	270	0	233	416	1	1
SMAD3	AEBP1	0	0	151	169	1	1
SMAD3	TNS1	0	0	227	253	1	1
SMAD3	CDX1	0	0	125	182	1	1
SMAD3	MTHFD1L	0	0	163	163	1	1
SMAD3	OTUB1	270	0	81	386	1	1
SMAD3	KLF5	270	0	510	647	1	2
SMAD3	CLDN3	0	0	165	165	1	1
SMAD3	GSDMB	0	0	580	580	1	1
SMAD3	TBX3	0	0	218	301	1	1
SMAD3	RBPMS	218	0	457	557	1	1
SMAD3	PAK2	0	0	128	209	1	1
SMAD3	FOXP1	0	0	211	368	1	1
SMAD3	MAGIX	0	0	0	174	1	1
SMAD3	IPO11	0	0	95	151	1	1
SMAD3	VIM	213	0	323	538	1	2
SMAD3	FZD7	0	0	235	281	1	1
SMAD3	BTG3	0	0	0	159	1	1
SMAD3	MEIS2	0	0	112	215	1	1
SMAD3	SKP2	0	0	265	288	1	2
SMAD3	ARG1	0	0	243	242	1	2
SMAD3	ADIPOQ	0	0	267	267	1	2
SMAD3	LTBP1	0	0	408	437	1	1
SMAD3	FASN	0	0	156	155	1	2
SMAD3	ETS1	600	0	649	871	1	1
SMAD3	IL17A	0	0	468	468	1	2
SMAD3	TLR7	0	0	149	164	1	2
SMAD3	MAPK9	213	800	252	877	1	2
SMAD3	MYL12A	0	0	52	172	1	1
SMAD3	NRP1	0	0	212	212	1	1
SMAD3	CHEK2	0	0	161	181	1	1
SMAD3	RPS6KA3	0	0	160	159	1	1
SMAD3	GDF2	0	0	391	471	1	1
SMAD3	NANOG	0	0	451	475	1	2
SMAD3	RPS6KA4	0	0	73	192	1	1
SMAD3	CASP9	0	0	260	260	1	2
SMAD3	KLF13	0	0	181	202	1	1
SMAD3	BPTF	270	0	72	376	1	1
SMAD3	TIE1	0	0	150	185	1	1
SMAD3	DAB2	270	900	261	942	1	1
SMAD3	RPTOR	0	0	263	279	1	2
SMAD3	NES	0	0	210	240	1	2
SMAD3	CEBPD	270	0	457	595	1	1
SMAD3	ITGA1	0	0	173	193	1	1
SMAD3	POTEJ	0	0	0	151	1	1
SMAD3	CDKN1C	0	0	233	280	1	1
SMAD3	CX3CR1	0	0	218	218	1	1
SMAD3	STK16	0	0	322	321	1	1
SMAD3	LIF	0	0	215	238	1	2
SMAD3	COL5A1	0	0	342	479	1	1
SMAD3	ACVR1	0	800	508	939	1	1
SMAD3	SDHAF2	0	0	161	167	1	1
SMAD3	FGF10	0	0	213	267	1	1
SMAD3	H1F0	0	0	134	167	1	1
SMAD3	RASAL1	0	0	181	239	1	1
SMAD3	UBE2D1	0	900	62	907	1	1
SMAD3	ENSG00000279576	0	0	231	230	1	1
SMAD3	PI3	0	0	181	181	1	2
SMAD3	NR2C1	0	0	88	182	1	1
SMAD3	HOXA9	0	0	216	267	1	1
SMAD3	USF1	0	0	282	282	1	1
SMAD3	TAB2	0	0	170	202	1	2
SMAD3	IGF1R	0	0	380	465	1	2
SMAD3	ZDHHC4	213	0	0	230	1	1
SMAD3	COL11A1	0	0	283	381	1	1
SMAD3	SDHC	0	0	452	471	1	1
SMAD3	PAX7	0	0	284	284	1	1
SMAD3	IL18	0	0	310	309	1	2
SMAD3	APEX1	0	0	138	227	1	1
SMAD3	HOXC4	0	0	167	239	1	1
SMAD3	IL1R1	0	0	234	234	1	1
SMAD3	GSC	128	0	108	375	1	1
SMAD3	MYC	270	900	937	995	1	2
SMAD3	TFAP2B	0	900	81	904	1	1
SMAD3	MMP17	0	0	0	263	1	1
SMAD3	NR4A3	0	0	157	175	1	1
SMAD3	SERPINA6	0	0	46	192	1	1
SMAD3	RARG	213	0	113	420	1	1
SMAD3	CERS1	0	0	150	274	1	1
SMAD3	PIK3CA	270	0	281	489	1	2
SMAD3	CTDSP1	0	900	108	918	1	1
SMAD3	EVX1	0	0	0	198	1	1
SMAD3	NOG	0	0	370	383	1	1
SMAD3	TAB1	0	0	230	281	1	1
SMAD3	MEN1	270	600	988	996	1	1
SMAD3	MX1	0	0	150	164	1	1
SMAD3	CHI3L1	0	0	156	208	1	1
SMAD3	SYNPO	0	0	167	203	1	1
SMAD3	PARK7	0	0	95	156	1	2
SMAD3	PARD3	270	0	75	316	1	1
SMAD3	FHL2	270	0	217	506	1	1
SMAD3	S1PR2	0	0	164	163	1	1
SMAD3	HOXB3	0	0	96	192	1	1
SMAD3	HDAC5	270	0	211	782	1	1
SMAD3	HIST1H4L	0	0	203	203	1	1
SMAD3	HDAC3	0	0	122	155	1	2
SMAD3	SAMD8	0	0	0	163	1	1
SMAD3	SMAD4	998	900	989	999	1	2
SMAD3	MYCN	0	0	230	246	1	1
SMAD3	MEF2D	0	0	193	350	1	2
SMAD3	SUCO	0	0	76	256	1	1
SMAD3	MAGI1	0	0	0	180	1	1
SMAD3	UBBP4	0	0	0	156	1	1
SMAD3	IKZF3	0	0	195	215	1	1
SMAD3	OSM	0	0	255	254	1	1
SMAD3	MAP2K1	0	0	433	464	1	1
SMAD3	EID1	0	0	296	296	1	1
SMAD3	CD80	0	0	218	218	1	2
SMAD3	FURIN	0	0	323	352	1	1
SMAD3	DSP	0	0	161	208	1	1
SMAD3	AKT2	0	0	248	380	1	2
SMAD3	GPR155	0	0	0	181	1	1
SMAD3	PLEKHA5	0	0	0	174	1	1
SMAD3	ZNF423	0	0	140	172	1	1
SMAD3	MNX1	0	0	70	150	1	1
SMAD3	TLR1	0	0	140	189	1	1
SMAD3	EHMT2	0	0	196	213	1	2
SMAD3	NFE2L2	0	0	296	341	1	2
SMAD3	BACH2	0	0	230	279	1	1
SMAD3	MECP2	0	0	206	210	1	1
SMAD3	CDK4	634	900	546	982	1	2
SMAD3	HIST1H4I	0	0	203	203	1	1
SMAD3	MYD88	131	0	294	368	1	2
SMAD3	SARM1	0	0	218	233	1	1
SMAD3	FADD	0	0	150	169	1	2
SMAD3	UCHL5	486	0	390	673	1	1
SMAD3	CFTR	0	0	166	187	1	2
SMAD3	KPNA4	0	0	74	325	1	1
SMAD3	COL5A2	0	0	334	437	1	1
SMAD3	PRKCI	0	0	70	188	1	1
SMAD3	SGCG	0	0	100	211	1	1
SMAD3	DHH	0	0	157	219	1	1
SMAD3	MCAT	0	0	145	213	1	1
SMAD3	KRT2	213	0	0	213	1	1
SMAD3	ADAM33	0	0	189	256	1	1
SMAD3	DDIT3	0	0	211	237	1	2
SMAD3	HOXB5	0	0	81	152	1	1
SMAD3	FGF7	0	0	260	343	1	1
SMAD3	SKOR1	0	0	701	765	1	1
SMAD3	HK2	270	0	108	325	1	2
SMAD3	PLOD1	0	0	257	273	1	1
SMAD3	CSF3	0	0	218	218	1	1
SMAD3	LMNA	213	0	241	440	1	2
SMAD3	PITX2	270	0	181	450	1	1
SMAD3	MUC5B	0	0	166	229	1	1
SMAD3	HGS	270	0	125	333	1	2
SMAD3	ZNF8	213	0	0	276	1	1
SMAD3	CTBP2	0	0	181	203	1	1
SMAD3	PIN1	653	0	126	769	1	1
SMAD3	CYBA	0	0	167	167	1	1
SMAD3	FOXE3	0	0	208	261	1	1
SMAD3	PSME3	0	0	150	220	1	1
SMAD3	PAK1	0	0	113	195	1	2
SMAD3	COL2A1	0	0	390	473	1	2
SMAD3	WNT5B	0	0	324	380	1	1
SMAD3	TSC22D3	0	0	142	237	1	1
SMAD3	PPP1R12C	111	0	70	169	1	1
SMAD3	STAT3	270	0	915	937	1	2
SMAD3	EZH2	42	0	529	530	1	2
SMAD3	ADAM9	0	0	125	217	1	1
SMAD3	DKK2	0	0	142	172	1	1
SMAD3	TGFA	0	0	261	261	1	1
SMAD3	AGO2	0	0	258	258	1	2
SMAD3	POU5F1B	0	0	0	343	1	1
SMAD3	NF2	0	0	172	171	1	1
SMAD3	NR2F1	0	0	144	168	1	1
SMAD3	GATA3	0	900	958	996	1	1
SMAD3	XRCC6	130	0	147	226	1	1
SMAD3	ERN1	0	0	95	157	1	2
SMAD3	TCF21	0	0	231	232	1	1
SMAD3	GAS1	0	0	134	153	1	1
SMAD3	ACVR1C	0	900	520	968	1	1
SMAD3	ID1	0	0	460	506	1	1
SMAD3	GABPA	0	0	95	171	1	1
SMAD3	UBE2R2	0	0	0	360	1	1
SMAD3	LATS2	0	0	150	213	1	1
SMAD3	SP1	874	900	930	999	1	2
SMAD3	TRIM66	0	0	90	181	1	1
SMAD3	IL1B	0	0	561	561	1	2
SMAD3	TRPM7	0	0	150	177	1	1
SMAD3	WNT7B	0	0	262	279	1	1
SMAD3	PRKCB	0	0	156	155	1	2
SMAD3	SMAD9	876	720	620	964	1	1
SMAD3	EDN1	0	0	425	450	1	1
SMAD3	HIF1A	765	900	977	999	1	2
SMAD3	SIRT5	0	0	205	237	1	1
SMAD3	CYP4B1	0	0	73	151	1	1
SMAD3	PRKAR2B	0	0	97	152	1	1
SMAD3	CALD1	0	0	202	202	1	1
SMAD3	XPO1	0	0	253	264	1	1
SMAD3	HERC5	0	0	61	192	1	1
SMAD3	RHO	0	0	66	288	1	2
SMAD3	CXCR2	0	0	211	224	1	1
SMAD3	HOXA11	0	0	108	182	1	1
SMAD3	ERBB2IP	734	0	929	982	1	1
SMAD3	EPHA2	0	0	139	241	1	1
SMAD3	CDK2	634	900	455	979	1	2
SMAD3	KPNA1	0	0	95	197	1	1
SMAD3	POTEF	0	0	209	299	1	1
SMAD3	SMO	0	0	0	221	1	1
SMAD3	SORT1	0	0	150	198	1	1
SMAD3	BMP3	0	0	211	315	1	1
SMAD3	LDLRAD4	447	0	162	557	1	1
SMAD3	KLF7	0	0	193	255	1	1
SMAD3	TBR1	0	0	134	209	1	1
SMAD3	NOTCH1	270	0	987	991	1	2
SMAD3	PTPN13	0	900	71	905	1	1
SMAD3	CCNC	0	900	150	914	1	1
SMAD3	ENTPD1	0	0	203	203	1	1
SMAD3	GRIP1	270	0	0	270	1	1
SMAD3	CD40LG	0	0	213	226	1	1
SMAD3	PRMT1	0	0	167	281	1	1
SMAD3	TRAF4	0	0	182	199	1	1
SMAD3	ADAMTSL2	0	0	123	161	1	1
SMAD3	FGF13	0	0	372	411	1	1
SMAD3	HLA-G	0	0	156	155	1	1
SMAD3	VPREB1	0	0	0	173	1	1
SMAD3	TNFRSF1A	0	0	230	229	1	1
SMAD3	RPS6	0	0	153	152	1	2
SMAD3	ACTN4	0	0	68	158	1	1
SMAD3	MYOG	0	0	402	492	1	1
SMAD3	E2F6	0	0	181	194	1	1
SMAD3	TBX2	0	0	143	234	1	1
SMAD3	BRD2	0	0	119	199	1	1
SMAD3	KCNA5	0	0	97	192	1	1
SMAD3	FOXO6	0	0	113	174	1	1
SMAD3	ACTR2	0	0	67	157	1	1
SMAD3	TNFRSF19	0	0	70	236	1	1
SMAD3	IL6	0	0	606	610	1	2
SMAD3	UCP2	0	0	112	170	1	2
SMAD3	VAV2	131	0	60	154	1	1
SMAD3	MPO	0	0	202	202	1	2
SMAD3	PRKG1	0	0	383	456	1	1
SMAD3	TGFB3	0	900	702	973	1	1
SMAD3	CCL5	0	0	321	321	1	2
SMAD3	TWSG1	0	0	123	211	1	1
SMAD3	IFNG	0	0	343	412	1	2
SMAD3	GAST	0	0	141	160	1	1
SMAD3	IGFBP5	0	0	263	279	1	1
SMAD3	HSPA1L	0	0	0	188	1	1
SMAD3	KCNC3	0	0	0	197	1	1
SMAD3	SLC2A10	0	0	507	507	1	1
SMAD3	NOTCH4	270	800	292	890	1	1
SMAD3	HAVCR1	0	0	224	224	1	1
SMAD3	PLK1	0	0	213	232	1	2
SMAD3	SIAH1	0	0	123	161	1	1
SMAD3	EPO	0	0	251	250	1	2
SMAD3	KLF3	0	0	175	196	1	1
SMAD3	GSDMA	0	0	193	193	1	1
SMAD3	PHEX	0	0	85	198	1	1
SMAD3	PDP2	0	0	0	262	1	1
SMAD3	RANBP2	0	0	66	166	1	1
SMAD3	FOXM1	270	0	834	885	1	1
SMAD3	LGALS9	0	0	81	201	1	1
SMAD3	TAGLN	0	0	581	590	1	1
SMAD3	PCSK6	0	0	119	158	1	1
SMAD3	HOXA7	0	0	82	229	1	1
SMAD3	HES1	0	0	188	188	1	2
SMAD3	FBXO32	0	0	404	417	1	2
SMAD3	WNT8A	0	0	216	246	1	1
SMAD3	ANXA5	0	0	340	381	1	2
SMAD3	CCNB1	0	0	261	329	1	1
SMAD3	NPPA	0	0	142	202	1	1
SMAD3	FGF21	0	0	181	316	1	2
SMAD3	BCL2L1	0	0	368	368	1	2
SMAD3	TUBB4A	0	0	134	175	1	1
SMAD3	SOX12	0	0	46	169	1	1
SMAD3	DNMT3A	0	0	282	282	1	2
SMAD3	PSRC1	0	0	234	234	1	1
SMAD3	DNMT3B	0	0	266	266	1	1
SMAD3	EPHA8	0	0	0	174	1	1
SMAD3	KITLG	0	0	211	228	1	1
SMAD3	COL11A2	0	0	112	233	1	1
SMAD3	ALDH1A2	0	0	166	165	1	1
SMAD3	CSMD1	0	0	448	458	1	1
SMAD3	NF1	0	0	212	229	1	1
SMAD3	HYAL2	270	0	113	336	1	1
SMAD3	NOS2	0	0	183	210	1	2
SMAD3	POTEE	0	0	0	151	1	1
SMAD3	SNW1	474	650	185	841	1	1
SMAD3	JAG2	0	0	288	388	1	1
SMAD3	OLIG1	0	0	701	701	1	1
SMAD3	ZFYVE16	0	800	205	855	1	1
SMAD3	SIX2	0	0	74	200	1	1
SMAD3	PTPN9	0	900	0	902	1	1
SMAD3	EGR3	0	0	202	222	1	1
SMAD3	TLR4	130	0	402	486	1	2
SMAD3	SMAD2	897	900	990	990	1	2
SMAD3	EMR1	0	0	0	189	1	1
SMAD3	GNAI3	0	0	0	224	1	2
SMAD3	SOX7	0	0	108	153	1	1
SMAD3	TFG	0	0	325	346	1	1
SMAD3	FZD5	0	0	167	214	1	1
SMAD3	STK17A	0	0	701	701	1	1
SMAD3	NAB2	0	0	123	276	1	1
SMAD3	BGN	0	0	322	348	1	1
SMAD3	CD86	0	0	218	218	1	1
SMAD3	LRRK2	0	0	81	189	1	2
SMAD3	MET	0	0	340	405	1	2
SMAD3	ERF	0	0	194	243	1	1
SMAD3	CDKN2B	0	900	517	950	1	1
SMAD3	TLR2	0	0	292	304	1	2
SMAD3	WEE1	128	0	183	274	1	1
SMAD3	SUFU	0	0	134	172	1	1
SMAD3	ALDH1A1	0	0	229	228	1	1
SMAD3	SFRP2	0	0	194	228	1	1
SMAD3	ZMYND11	111	0	0	177	1	1
SMAD3	SOD2	0	0	213	213	1	2
SMAD3	CCDC97	0	0	150	210	1	1
SMAD3	DRAP1	0	900	45	900	1	1
SMAD3	CDK9	270	900	439	956	1	1
SMAD3	DUSP3	0	0	112	163	1	1
SMAD3	ADRBK1	0	0	139	157	1	1
SMAD3	EPAS1	628	0	161	703	1	2
SMAD3	TGFB1I1	486	0	954	976	1	1
SMAD3	FOXO1	270	900	721	979	1	2
SMAD3	BTRC	462	0	465	711	1	1
SMAD3	EIF4A2	0	0	60	182	1	1
SMAD3	NRAS	0	0	135	188	1	1
SMAD3	TFE3	678	900	698	989	1	2
SMAD3	FOXP2	0	0	142	273	1	1
SMAD3	HSPA5	0	0	181	181	1	2
SMAD3	E2F1	0	0	254	266	1	2
SMAD3	MSTN	0	900	652	976	1	1
SMAD3	PDX1	0	0	74	150	1	1
SMAD3	PTPN11	0	900	234	928	1	1
SMAD3	IRAK3	0	0	125	191	1	1
SMAD3	SIGIRR	0	0	260	260	1	1
SMAD3	ANGPTL4	0	0	283	316	1	1
SMAD3	INHBB	0	900	284	943	1	1
SMAD3	RBM39	0	0	0	159	1	1
SMAD3	GDF6	0	0	232	331	1	1
SMAD3	FOS	486	900	826	990	1	2
SMAD3	YWHAZ	0	0	219	227	1	1
SMAD3	S100A8	0	0	722	722	1	2
SMAD3	HEY2	0	0	453	464	1	1
SMAD3	TWIST1	0	0	496	529	1	1
SMAD3	RIN2	0	0	74	234	1	1
SMAD3	CSF1	0	0	261	286	1	1
SMAD3	HDAC1	500	900	815	990	1	2
SMAD3	CKB	0	0	0	158	1	1
SMAD3	PRDM1	0	0	231	230	1	1
SMAD3	CRYAB	0	0	76	169	1	2
SMAD3	MEF2A	0	0	260	330	1	1
SMAD3	DNAJA2	257	0	0	274	1	1
SMAD3	CHD8	131	0	82	189	1	1
SMAD3	KLF2	0	0	302	380	1	1
SMAD3	CUL3	0	0	150	168	1	2
SMAD3	CHUK	270	0	676	779	1	1
SMAD3	HIST2H4A	0	0	203	203	1	1
SMAD3	WNT2	0	0	270	508	1	1
SMAD3	USF2	0	0	183	183	1	1
SMAD3	RBL2	0	0	147	165	1	1
SMAD3	PBRM1	0	0	72	161	1	1
SMAD3	BLK	0	0	113	174	1	1
SMAD3	ITGAX	0	0	231	230	1	1
SMAD3	SFN	0	0	161	161	1	2
SMAD3	FABP4	0	0	160	159	1	1
SMAD3	BMPR1B	0	800	469	929	1	1
SMAD3	SOCS2	0	0	171	183	1	1
SMAD3	MGP	0	0	141	180	1	1
SMAD3	PTPN12	0	900	57	903	1	1
SMAD3	GDF11	0	0	458	642	1	1
SMAD3	NR2C2	0	0	125	205	1	1
SMAD3	CXCL5	0	0	210	210	1	1
SMAD3	CD28	0	0	390	390	1	1
SMAD3	TET1	0	0	193	193	1	1
SMAD3	PRMT2	0	0	0	187	1	1
SMAD3	PRKCQ	0	0	124	178	1	2
SMAD3	ATG12	0	0	125	157	1	2
SMAD3	ALOX5	0	0	166	165	1	1
SMAD3	BCAR1	0	0	692	699	1	1
SMAD3	PTPN5	0	900	0	902	1	1
SMAD3	CYP46A1	0	0	66	178	1	1
SMAD3	FGF22	0	0	0	244	1	1
SMAD3	NOTCH2	0	0	484	548	1	1
SMAD3	NQO1	0	0	194	194	1	2
SMAD3	FGF19	0	0	75	276	1	1
SMAD3	CCL11	0	0	152	151	1	1
SMAD3	AICDA	0	0	137	174	1	1
SMAD3	IL1RL1	0	0	395	394	1	1
SMAD3	LIMK1	0	0	181	258	1	1
SMAD3	DAXX	0	0	234	266	1	1
SMAD3	NFIB	0	0	141	166	1	1
SMAD3	MYO5B	213	0	0	213	1	1
SMAD3	CDC27	270	0	90	356	1	1
SMAD3	AFP	0	0	208	227	1	2
SMAD3	MMP14	0	0	294	340	1	1
SMAD3	KLF14	0	0	150	172	1	1
SMAD3	HSPA1B	257	0	0	401	1	1
SMAD3	TRIB3	270	0	830	871	1	2
SMAD3	BLZF1	135	0	0	153	1	1
SMAD3	CXCL1	0	0	277	277	1	2
SMAD3	IL33	0	0	400	400	1	2
SMAD3	HECW2	0	0	60	191	1	1
SMAD3	PTEN	0	0	583	662	1	2
SMAD3	NCOA6	66	0	124	213	1	1
SMAD3	ID3	0	0	323	422	1	1
SMAD3	SALL1	0	0	139	164	1	1
SMAD3	MAPK7	0	0	281	339	1	1
SMAD3	NFIA	270	0	134	340	1	1
SMAD3	IRF4	0	0	495	495	1	1
SMAD3	KDM5C	270	0	460	598	1	1
SMAD3	VEGFA	0	0	595	595	1	2
SMAD3	ARID2	0	0	155	200	1	1
SMAD3	SNIP1	0	900	167	913	1	1
SMAD3	PMEPA1	0	600	322	758	1	1
SMAD3	POU6F1	0	0	0	562	1	1
SMAD3	COL10A1	0	0	244	257	1	1
SMAD3	MYOD1	213	900	935	998	1	1
SMAD3	S1PR1	0	0	243	259	1	1
SMAD3	LEP	0	0	286	287	1	1
SMAD3	SYK	0	0	139	215	1	2
SMAD3	SAMD7	0	0	186	186	1	1
SMAD3	NFKBIA	0	0	402	430	1	2
SMAD3	ONECUT2	0	0	134	152	1	1
SMAD3	WT1	0	0	293	311	1	1
SMAD3	FHL1	270	0	0	276	1	1
SMAD3	CLIC4	0	0	398	410	1	1
SMAD3	ZBTB33	0	0	124	198	1	1
SMAD3	ZC3H12A	111	0	82	166	1	1
SMAD3	TCF4	0	0	164	203	1	1
SMAD3	BMP4	0	0	639	809	1	1
SMAD3	UCP1	0	0	252	252	1	2
SMAD3	SREBF1	0	0	262	293	1	1
SMAD3	PTH1R	0	0	137	150	1	1
SMAD3	UBA52	0	600	0	600	1	1
SMAD3	MAPK10	0	800	147	830	1	2
SMAD3	HIST1H4A	0	0	203	203	1	1
SMAD3	TIMP3	0	0	325	326	1	1
SMAD3	LMNB2	0	0	108	194	1	1
SMAD3	MEOX2	117	0	123	243	1	1
SMAD3	MAPK14	213	0	412	632	1	2
SMAD3	CFL1	0	0	186	186	1	1
SMAD3	FERMT2	0	0	628	636	1	1
SMAD3	SMAD5	257	720	821	791	1	1
SMAD3	ZNF469	0	0	171	212	1	1
SMAD3	ATM	0	0	323	337	1	2
SMAD3	SFRP1	0	0	246	277	1	1
SMAD3	SHC1	0	0	310	309	1	1
SMAD3	LRRC1	0	0	0	162	1	1
SMAD3	BAMBI	0	0	420	420	1	1
SMAD3	TRIM63	0	900	324	931	1	1
SMAD3	IL23A	0	0	149	267	1	1
SMAD3	CTSD	0	0	129	156	1	2
SMAD3	AXIN1	213	900	933	995	1	1
SMAD3	TYRO3	0	0	96	165	1	1
SMAD3	CYGB	0	0	143	177	1	1
SMAD3	ENSG00000267261	0	0	0	190	1	1
SMAD3	LHCGR	0	0	125	165	1	1
SMAD3	GNAI1	0	0	0	224	1	1
SMAD3	SIK3	257	0	49	309	1	1
SMAD3	PLEKHA7	0	0	0	174	1	1
SMAD3	RET	0	0	171	220	1	1
SMAD3	HIVEP2	0	0	388	420	1	1
SMAD3	ACTG1	0	0	235	274	1	1
SMAD3	IKZF1	0	0	181	202	1	1
SMAD3	ITGB5	0	0	194	213	1	1
SMAD3	BTG2	0	0	136	264	1	1
SMAD3	CDH11	0	0	253	265	1	1
SMAD3	ATG7	0	0	172	198	1	2
SMAD3	TGFBR2	213	900	858	989	1	1
SMAD3	DHX8	257	0	0	365	1	1
SMAD3	SELE	0	0	159	174	1	1
SMAD3	RXRG	0	0	134	189	1	1
SMAD3	TJP1	0	0	469	496	1	1
SMAD3	TRAT1	0	0	134	156	1	1
SMAD3	RBPJ	0	0	423	448	1	1
SMAD3	CXCL2	0	0	205	205	1	1
SMAD3	ITGB4	257	0	164	366	1	1
SMAD3	COL1A1	0	0	593	756	1	2
SMAD3	PPARGC1B	0	0	84	150	1	1
SMAD3	PTK7	0	0	75	167	1	1
SMAD3	MTDH	0	0	172	176	1	2
SMAD3	CCL20	0	0	183	183	1	1
SMAD3	EFNB2	0	0	162	180	1	1
SMAD3	STRAP	270	900	241	940	1	1
SMAD3	GFAP	0	0	181	181	1	2
SMAD3	CHD4	0	0	92	167	1	1
SMAD3	HSPB2	0	0	172	172	1	1
SMAD3	DYRK1A	131	0	134	242	1	1
SMAD3	CMA1	0	0	210	222	1	1
SMAD3	ENSG00000255819	0	0	218	231	1	1
SMAD3	GLI1	0	0	404	431	1	2
SMAD3	HSPB1	0	0	181	181	1	2
SMAD3	ADAM19	0	0	166	235	1	1
SMAD3	TGFBR1	866	900	986	999	1	1
SMAD3	S100A4	270	0	916	936	1	1
SMAD3	ADAM17	0	0	243	260	1	1
SMAD3	ARID1A	270	0	281	469	1	1
SMAD3	SERPINB9	0	0	82	154	1	1
SMAD3	TMEFF1	0	0	125	185	1	1
SMAD3	SERPINB8	0	0	0	174	1	1
SMAD3	FOXB1	0	0	95	171	1	1
SMAD3	NFKBIB	0	0	96	166	1	1
SMAD3	CHD3	0	0	59	154	1	1
SMAD3	PIAS3	270	900	729	979	1	1
SMAD3	LATS1	0	0	184	223	1	1
SMAD3	HNRNPK	111	0	107	191	1	1
SMAD3	NCAM1	0	0	151	194	1	1
SMAD3	KLF16	0	0	181	202	1	1
SMAD3	DACH1	270	0	151	383	1	1
SMAD3	TBX21	0	0	450	470	1	1
SMAD3	MAP3K12	0	0	66	160	1	1
SMAD3	STMN1	0	0	162	292	1	1
SMAD3	POU2F2	0	0	143	176	1	1
SMAD3	RPS6KA1	0	0	194	194	1	1
SMAD3	SKIL	870	900	981	999	1	1
SMAD3	THPO	0	0	72	390	1	1
SMAD3	AKT3	0	0	194	336	1	2
SMAD3	CXCR5	0	0	142	156	1	1
SMAD3	RARA	0	0	224	296	1	2
SMAD3	IKBKG	0	0	183	254	1	1
SMAD3	CCR7	0	0	210	210	1	1
SMAD3	GPX1	0	0	134	169	1	1
SMAD3	KDM5B	0	0	156	174	1	1
SMAD3	VTN	0	0	211	240	1	1
SMAD3	RALA	0	0	115	193	1	1
SMAD3	PCBP1	0	0	912	912	1	1
SMAD3	MCL1	0	0	241	240	1	2
SMAD3	SIRT1	0	0	574	632	1	2
SMAD3	SMARCA4	270	0	724	791	1	1
SMAD3	HECTD3	0	0	0	174	1	1
SMAD3	DLK1	0	0	195	212	1	1
SMAD3	NOX1	0	0	392	404	1	1
SMAD3	SPI1	0	0	385	475	1	1
SMAD3	RBBP4	0	900	98	914	1	1
SMAD3	IRF5	0	0	160	159	1	1
SMAD3	HMGB1	0	0	233	252	1	2
SMAD3	DUOX2	0	0	180	179	1	1
SMAD3	RAC1	0	0	160	192	1	2
SMAD3	LYN	0	0	89	151	1	1
SMAD3	CTSK	0	0	183	183	1	2
SMAD3	RNH1	0	0	160	159	1	1
SMAD3	EYA4	0	0	90	238	1	1
SMAD3	T	0	0	49	333	1	1
SMAD3	SMARCD2	0	0	0	169	1	1
SMAD3	ITGAM	0	0	310	309	1	1
SMAD3	EIF5A	0	0	158	157	1	2
SMAD3	GATA2	0	0	261	386	1	1
SMAD3	MAP3K5	0	0	247	246	1	1
SMAD3	ACKR2	0	0	181	194	1	1
SMAD3	PCDH1	66	0	475	509	1	1
SMAD3	KCP	0	0	203	301	1	1
SMAD3	ITGB3	0	0	247	274	1	1
SMAD3	YIPF1	0	0	193	193	1	1
SMAD3	CAMK2G	600	0	48	619	1	1
SMAD3	WNT3A	0	0	379	430	1	2
SMAD3	MT-ND1	0	0	0	189	1	1
SMAD3	HTATIP2	0	0	107	168	1	1
SMAD3	ATG5	0	0	195	212	1	2
SMAD3	MAP2K6	0	0	157	197	1	1
SMAD3	GATA6	0	0	288	376	1	1
SMAD3	SAMD3	0	0	566	603	1	1
SMAD3	MPL	0	0	44	434	1	1
SMAD3	PUM1	0	0	0	195	1	1
SMAD3	PTPN1	0	0	138	155	1	1
SMAD3	XBP1	0	0	181	181	1	2
SMAD3	SOX6	0	0	231	336	1	1
SMAD3	STAT2	0	0	175	223	1	1
SMAD3	HIPK2	270	0	290	510	1	2
SMAD3	TP63	0	0	157	399	1	2
SMAD3	SP3	0	900	234	924	1	1
SMAD3	NOV	0	0	194	194	1	1
SMAD3	EYA3	0	0	0	180	1	1
SMAD3	TANK	131	0	63	150	1	2
SMAD3	SMARCD1	0	0	66	175	1	1
SMAD3	YBX1	213	0	463	569	1	1
SMAD3	EYA1	0	0	63	215	1	1
SMAD3	DPP10	0	0	146	164	1	1
SMAD3	LTBP4	0	0	294	377	1	1
SMAD3	SIX1	0	0	286	308	1	1
SMAD3	MYF6	0	0	211	317	1	1
SMAD3	PAFAH1B1	0	0	0	171	1	1
SMAD3	IL7	0	0	233	232	1	1
SMAD3	ADAMTS4	0	0	261	274	1	1
SMAD3	CD44	0	0	458	485	1	2
SMAD3	BDNF	0	0	212	212	1	2
SMAD3	GPC2	0	0	63	173	1	1
SMAD3	DKK3	0	0	195	214	1	1
SMAD3	PDLIM5	0	0	167	197	1	1
SMAD3	MMP7	0	0	324	434	1	1
SMAD3	GPC5	0	0	69	196	1	1
SMAD3	VCL	0	0	241	292	1	1
SMAD3	NME1	0	0	157	156	1	1
SMAD3	NRIP1	0	0	180	236	1	1
SMAD3	TMSB4X	0	0	153	152	1	1
SMAD3	HERC6	0	0	0	174	1	1
SMAD3	GPC1	0	0	141	217	1	1
SMAD3	BRE	0	0	303	318	1	1
SMAD3	XPO6	270	0	81	315	1	1
SMAD3	C11orf30	0	0	212	229	1	1
SMAD3	IL23R	0	0	294	294	1	1
SMAD3	ACVR2A	0	900	520	969	1	1
SMAD3	TSSK1B	0	0	203	203	1	1
SMAD3	RPLP0	72	0	103	157	1	1
SMAD3	CCNT2	0	900	52	904	1	1
SMAD3	DDX3X	131	0	59	166	1	1
SMAD3	POU2F1	0	0	124	191	1	1
SMAD3	CD63	0	0	142	160	1	2
SMAD3	VWF	0	0	245	266	1	1
SMAD3	U2AF2	257	0	75	310	1	1
SMAD3	SOX5	0	0	230	253	1	1
SMAD3	ENSG00000272980	0	0	211	224	1	1
SMAD3	HIST1H4H	0	0	203	203	1	1
SMAD3	SOS1	0	0	135	174	1	1
SMAD3	AXIN2	213	0	415	560	1	1
SMAD3	POTEI	0	0	0	151	1	1
SMAD3	PTCH1	0	0	290	327	1	1
SMAD3	FGF2	0	0	470	497	1	2
SMAD3	RELB	270	0	245	425	1	2
SMAD3	FOXK2	0	0	113	173	1	1
SMAD3	LACRT	270	0	0	270	1	1
SMAD3	FAM83G	257	0	82	288	1	1
SMAD3	OLFML3	0	0	113	150	1	1
SMAD3	PLEKHA4	270	0	0	277	1	1
SMAD3	SFRP4	0	0	166	243	1	1
SMAD3	ESRRB	0	0	193	216	1	1
SMAD3	PKM	0	0	170	169	1	1
SMAD3	GADD45A	0	0	227	283	1	1
SMAD3	EPHB4	0	0	129	236	1	1
SMAD3	SDC4	0	0	195	195	1	1
SMAD3	PPP2R5C	0	0	67	150	1	1
SMAD3	PPP2R1A	130	0	164	251	1	1
SMAD3	MAPK1	658	900	390	981	1	2
SMAD3	ITGA3	0	0	157	177	1	2
SMAD3	IGF1	0	0	470	479	1	2
SMAD3	TNMD	0	0	344	343	1	1
SMAD3	CSF1R	0	0	204	220	1	1
SMAD3	APOB	111	0	159	220	1	2
SMAD3	NEDD4L	965	600	701	996	1	1
SMAD3	CCND3	0	0	210	245	1	1
SMAD3	SOCS1	0	0	294	304	1	1
SMAD3	BTK	0	0	74	166	1	1
SMAD3	HIVEP1	187	0	295	648	1	1
SMAD3	HEY1	130	0	340	414	1	1
SMAD3	GPC6	0	0	85	198	1	1
SMAD3	KAT2B	835	900	728	995	1	1
SMAD3	PRRX2	0	0	93	170	1	1
SMAD3	EIF4E	0	0	194	211	1	2
SMAD3	PPP2CA	0	0	115	219	1	1
SMAD3	HIST2H2BE	0	0	158	157	1	1
SMAD3	ETV6	0	0	108	202	1	1
SMAD3	RANBP3	270	0	233	497	1	1
SMAD3	HMGCR	0	0	152	151	1	1
SMAD3	KLF1	0	0	160	193	1	1
SMAD3	CYP24A1	0	0	160	174	1	1
SMAD3	SKIV2L2	0	0	0	158	1	1
SMAD3	ANXA2	0	0	170	169	1	1
SMAD3	PSPC1	257	0	60	273	1	1
SMAD3	NCF1	0	0	189	189	1	1
SMAD3	UBE2I	0	0	170	202	1	1
SMAD3	CD19	0	0	175	175	1	1
SMAD3	FGF5	0	0	155	239	1	1
SMAD3	WNT9A	0	0	267	369	1	1
SMAD3	ARHGEF7	131	0	49	164	1	1
SMAD3	LOXL1	0	0	140	161	1	1
SMAD3	FLI1	117	0	75	224	1	1
SMAD3	MEIS1	0	0	167	264	1	1
SMAD3	FRAT1	0	0	145	164	1	1
SMAD3	CCND1	0	0	556	595	1	2
SMAD3	FSHR	0	0	181	186	1	1
SMAD3	ACTA2	0	0	549	754	1	1
SMAD3	NR5A1	0	0	214	214	1	1
SMAD3	NOS3	0	0	345	359	1	2
SMAD3	JUND	270	0	675	781	1	1
SMAD3	TRPS1	0	0	218	314	1	1
SMAD3	E2F8	0	0	180	203	1	1
SMAD3	GNB2L1	0	0	173	192	1	1
SMAD3	COL7A1	0	0	202	301	1	1
SMAD3	LDLR	0	0	222	222	1	2
SMAD3	SH2D2A	270	0	85	303	1	1
SMAD3	KLF9	0	0	151	173	1	1
SMAD3	MSI2	0	0	167	179	1	1
SMAD3	RHEB	0	0	154	172	1	2
SMAD3	ALPL	0	0	190	276	1	1
SMAD3	MDK	0	0	70	231	1	1
SMAD3	HIST2H4B	0	0	203	203	1	1
SMAD3	NR1D1	0	0	116	163	1	2
SMAD3	SCX	0	0	657	840	1	1
SMAD3	CCNE1	0	0	261	357	1	1
SMAD3	NPHS2	0	0	182	181	1	2
SMAD3	FOXP4	0	0	73	214	1	1
SMAD3	SAP18	0	900	0	900	1	1
SMAD3	TXN	0	0	171	183	1	1
SMAD3	LRP6	0	0	275	294	1	1
SMAD3	ENSG00000264813	0	0	391	399	1	1
SMAD3	BMP5	0	0	306	471	1	1
SMAD3	FSTL1	0	0	185	208	1	1
SMAD3	CCNK	0	900	0	903	1	1
SMAD3	PECAM1	0	0	409	423	1	1
SMAD3	UBB	0	600	0	648	1	1
SMAD3	NKX2-5	0	0	242	334	1	1
SMAD3	PTK2B	0	0	163	182	1	1
SMAD3	RUNX1	486	900	729	985	1	2
SMAD3	CACYBP	0	0	67	150	1	1
SMAD3	COL6A3	0	0	203	291	1	1
SMAD3	SAV1	0	0	120	159	1	1
SMAD3	HIST1H4D	0	0	203	203	1	1
SMAD3	METTL14	270	0	86	377	1	1
SMAD3	FOXP3	0	0	638	978	1	2
SMAD3	PTPN6	131	900	66	917	1	1
SMAD3	MGST1	0	0	0	211	1	1
SMAD3	YTHDC2	0	0	0	187	1	1
SMAD3	ASPN	0	0	216	229	1	1
SMAD3	TBK1	0	0	90	153	1	2
SMAD3	TUBB2A	0	0	60	204	1	1
SMAD3	RAB11A	0	0	125	162	1	2
SMAD3	RAC2	0	0	143	232	1	1
SMAD3	YY1	474	0	334	649	1	1
SMAD3	AGTR2	0	0	170	183	1	1
SMAD3	NKX3-1	0	0	155	208	1	1
SMAD3	PRMT5	282	0	150	363	1	1
SMAD3	CLDN4	0	0	157	167	1	1
SMAD3	ZNF83	130	0	0	152	1	1
SMAD3	SKP1	0	800	211	839	1	2
SMAD3	KDR	0	0	339	352	1	2
SMAD3	DDX20	0	0	97	230	1	1
SMAD3	ZNF384	0	0	165	186	1	1
SMAD3	IKZF2	0	0	172	201	1	1
SMAD3	KLF8	0	0	218	238	1	1
SMAD3	ARID3B	0	0	60	181	1	1
SMAD3	LUM	0	0	202	216	1	1
SMAD3	STAT5B	0	0	618	650	1	1
SMAD3	KRT19	0	0	330	330	1	1
SMAD3	TGFB1	107	900	710	985	1	2
SMAD3	MMP10	0	0	204	295	1	1
SMAD3	DIO2	0	0	171	177	1	1
SMAD3	USP7	224	0	124	291	1	1
SMAD3	PRKCD	0	0	289	288	1	2
SMAD3	CNN1	0	0	202	208	1	1
SMAD3	ITGA6	0	0	188	211	1	1
SMAD3	BGLAP	0	0	377	392	1	1
SMAD3	TNFSF11	0	0	324	323	1	2
SMAD3	ACTG2	0	0	150	295	1	1
SMAD3	BMPER	0	0	188	288	1	1
SMAD3	APOE	0	0	273	273	1	2
SMAD3	CBFB	0	900	0	900	1	1
SMAD3	SLC2A4	0	0	165	198	1	1
SMAD3	GATA5	0	0	173	293	1	1
SMAD3	FOXO3	676	900	630	989	1	2
SMAD3	DKK1	0	0	364	385	1	1
SMAD3	IRF8	0	0	193	193	1	1
SMAD3	CDC42	0	0	321	366	1	2
SMAD3	RAG1	0	0	182	181	1	1
SMAD3	SIN3B	0	900	67	911	1	1
SMAD3	CDKN3	0	0	320	332	1	1
SMAD3	TLR3	0	0	209	223	1	2
SMAD3	CORO1A	131	0	73	159	1	1
SMAD3	JDP2	0	0	108	596	1	1
SMAD3	MIF	0	0	150	168	1	2
SMAD3	LPAR1	0	0	165	178	1	1
SMAD3	EID2	270	0	306	471	1	1
SMAD3	CXXC5	130	0	135	215	1	1
SMAD3	RASA3	0	0	0	164	1	1
SMAD3	HNF4A	270	900	867	990	1	1
SMAD3	SERPINB7	0	0	0	156	1	1
SMAD3	TMEM232	0	0	180	179	1	1
SMAD3	EWSR1	0	0	154	161	1	1
SMAD3	TP53INP1	0	0	96	183	1	2
SMAD3	BMP8B	0	0	218	319	1	1
SMAD3	GPT	0	0	269	285	1	1
SMAD3	CCDC33	273	0	46	294	1	1
SMAD3	GDF1	0	0	172	293	1	1
SMAD3	PHGDH	0	0	178	190	1	1
SMAD3	FOXH1	698	600	921	990	1	1
SMAD3	NFATC4	0	0	180	179	1	1
SMAD3	BCL6	0	0	270	289	1	1
SMAD3	GJA1	0	0	310	323	1	1
SMAD3	PTPN23	0	900	0	904	1	1
SMAD3	RBBP5	270	0	107	364	1	1
SMAD3	AXL	0	0	242	309	1	2
SMAD3	FOXO4	270	900	286	948	1	1
SMAD3	PEX6	213	0	57	329	1	1
SMAD3	HSP90AB1	0	0	96	424	1	2
SMAD3	EYA2	0	0	95	214	1	1
SMAD3	CYLD	0	0	171	301	1	1
SMAD3	EIF4EBP1	0	0	249	248	1	2
SMAD3	KRT18	0	0	217	217	1	1
SMAD3	BSCL2	0	0	0	216	1	1
SMAD3	TPM3	213	0	48	218	1	1
SMAD3	CTCFL	0	0	134	175	1	1
SMAD3	FOXQ1	0	0	93	154	1	1
SMAD3	NR5A2	0	0	145	164	1	1
SMAD3	TGFBI	0	0	404	437	1	1
SMAD3	SQRDL	257	0	0	256	1	1
SMAD3	FBN1	0	0	604	635	1	1
SMAD3	CREM	0	0	218	236	1	1
SMAD3	CD34	0	0	323	337	1	2
SMAD3	NGF	0	0	194	194	1	2
SMAD3	ECE1	0	0	108	213	1	1
SMAD3	MED24	270	0	0	273	1	1
SMAD3	FOXJ1	0	0	134	192	1	1
SMAD3	FOXF1	0	0	139	239	1	1
SMAD3	YES1	0	0	56	199	1	1
SMAD3	KLK4	0	0	139	171	1	1
SMAD3	ACVR1B	270	900	710	985	1	1
SMAD3	CPT1A	0	0	124	200	1	1
SMAD3	LHX3	0	0	86	259	1	1
SMAD3	HIST1H4C	0	0	203	203	1	1
SMAD3	CSF2	0	0	321	321	1	1
SMAD3	FBN2	0	0	370	407	1	1
SMAD3	SUMO1	0	0	445	457	1	1
SMAD3	FAS	0	0	141	165	1	2
SMAD3	MXD1	0	0	134	159	1	1
SMAD3	VCAM1	0	0	322	321	1	1
SMAD3	MZF1	0	0	122	215	1	1
SMAD3	COL4A2	0	0	160	304	1	1
SMAD3	ZNF398	0	0	388	404	1	1
SMAD3	NTRK2	0	0	91	173	1	1
SMAD3	CDK8	270	900	323	958	1	1
SMAD3	TGIF2	270	900	193	940	1	1
SMAD3	SCN5A	0	0	101	473	1	1
SMAD3	GDF7	0	0	181	286	1	1
SMAD3	TGIF1	629	800	475	963	1	1
SMAD3	SKI	900	900	212	995	1	1
SMAD3	DUOX1	0	0	205	205	1	1
SMAD3	E2F4	270	900	988	999	1	1
SMAD3	SBK3	118	0	0	154	1	1
SMAD3	CST3	0	0	164	170	1	1
SMAD3	NOX4	0	0	556	558	1	2
SMAD3	DROSHA	270	0	907	941	1	1
SMAD3	KMT2D	0	0	155	162	1	1
SMAD3	COL4A3	0	0	134	217	1	1
SMAD3	MTMR4	270	600	95	723	1	1
SMAD3	CTDSP2	0	900	82	921	1	1
SMAD3	MKX	0	0	670	692	1	1
SMAD3	TYK2	0	0	216	269	1	1
SMAD3	FZD1	0	0	195	266	1	1
SMAD3	DAPK1	0	0	162	180	1	2
SMAD3	JUN	753	900	985	999	1	2
SMAD3	CYP19A1	0	0	243	255	1	2
SMAD3	ENSG00000173366	0	0	181	195	1	1
SMAD3	TBX20	0	0	115	191	1	1
SMAD3	CDH17	0	0	341	351	1	1
SMAD3	GZMA	0	0	123	156	1	1
SMAD3	NPPB	0	0	235	236	1	1
SMAD3	SERPINB2	0	0	94	205	1	1
SMAD3	ZBTB3	97	0	74	150	1	1
SMAD3	PIK3CG	0	0	163	208	1	1
SMAD3	JAK3	0	0	204	268	1	1
SMAD3	ZBTB16	72	0	181	228	1	1
SMAD3	COL18A1	0	0	141	191	1	1
SMAD3	SIX4	0	0	66	155	1	1
SMAD3	EIF4ENIF1	213	0	0	304	1	1
SMAD3	ERBB4	0	0	249	287	1	1
SMAD3	ARID5B	0	0	108	155	1	1
SMAD3	CCNA2	0	0	324	385	1	1
SMAD3	FZD10	0	0	138	181	1	1
SMAD3	GPC4	0	0	81	195	1	1
SMAD3	RYK	0	0	125	158	1	1
SMAD3	NCOA2	0	900	150	920	1	1
SMAD3	CYP7A1	0	0	122	155	1	1
SMAD3	DNTT	0	0	205	205	1	1
SMAD3	PRKACB	0	0	373	373	1	1
SMAD3	CSNK1G2	270	0	457	594	1	1
SMAD3	NCOA3	270	0	261	449	1	1
SMAD3	RUNX3	675	900	870	995	1	1
SMAD3	NFATC3	0	0	243	259	1	1
SMAD3	ID4	0	0	164	170	1	1
SMAD3	KRT8	0	0	246	245	1	1
SMAD3	COL3A1	0	0	561	645	1	1
SMAD3	LGALS7B	0	0	635	759	1	1
SMAD3	NEDD9	835	0	860	976	1	1
SMAD3	SMAD1	457	800	447	891	1	2
SMAD3	BTG1	0	0	0	159	1	1
SMAD3	IRS2	0	0	210	216	1	1
SMAD3	BMP6	0	0	459	597	1	1
SMAD3	PUM2	0	0	0	178	1	1
SMAD3	ZBTB7A	0	0	66	181	1	1
SMAD3	FGF6	0	0	0	268	1	1
SMAD3	SOX17	0	0	215	238	1	1
SMAD3	SPTBN1	270	900	376	973	1	1
SMAD3	CITED1	0	900	52	901	1	1
SMAD3	KPNA2	0	900	63	912	1	1
SMAD3	TBL1X	0	0	211	250	1	1
SMAD3	CDC25C	0	0	134	207	1	2
SMAD3	LTA	0	0	130	193	1	1
SMAD3	SOD1	0	0	137	160	1	2
SMAD3	IL7R	0	0	202	202	1	1
SMAD3	ARNT	0	900	213	918	1	2
SMAD3	IL36RN	270	0	60	333	1	1
SMAD3	BMI1	0	0	278	293	1	1
SMAD3	FST	0	0	505	555	1	1
SMAD3	JAG1	0	0	464	553	1	1
SMAD3	ABI1	0	0	0	158	1	1
SMAD3	DOCK9	257	0	0	273	1	1
SMAD3	FYN	0	0	213	332	1	1
SMAD3	MAX	632	900	107	965	1	2
SMAD3	GRB2	131	0	323	413	1	1
SMAD3	PHC2	161	0	0	181	1	1
SMAD3	SOX9	270	0	731	813	1	1
SMAD3	FOXA3	0	0	86	163	1	1
SMAD3	SAR1A	0	0	0	539	1	1
SMAD3	CCNB2	0	0	134	210	1	1
SMAD3	ICAM1	0	0	338	352	1	2
SMAD3	ITGAV	0	0	235	259	1	1
SMAD3	ELAC2	270	0	68	303	1	1
SMAD3	CKM	0	0	57	195	1	1
SMAD3	KPNA5	0	0	74	166	1	1
SMAD3	IGFBP2	0	0	141	156	1	1
SMAD3	SF3B2	213	0	444	595	1	1
SMAD3	WISP2	0	0	210	210	1	1
SMAD3	ZBTB7B	0	0	142	185	1	1
SMAD3	SOST	0	0	247	246	1	1
SMAD3	PRG4	0	0	157	171	1	1
SMAD3	PTPRC	0	0	370	397	1	1
SMAD3	HOXD10	0	0	143	199	1	1
SMAD3	MIXL1	0	0	218	297	1	1
SMAD3	GDF3	0	0	157	302	1	1
SMAD3	AURKA	0	0	150	190	1	2
SMAD3	CITED2	270	0	203	393	1	1
SMAD3	TNNI3	0	0	142	213	1	1
SMAD3	BAX	0	0	193	193	1	2
SMAD3	GPR29	0	0	211	224	1	1
SMAD3	TIMP1	0	0	563	569	1	1
SMAD3	GNA12	0	0	81	172	1	1
SMAD3	PJA1	131	0	250	346	1	1
SMAD3	SPP1	0	0	414	422	1	2
SMAD3	CDKN1A	270	900	518	962	1	2
SMAD3	GNRH1	0	0	209	258	1	1
SMAD3	SOX8	0	0	126	205	1	1
SMAD3	AR	675	900	960	998	1	2
SMAD3	MMP9	0	0	610	654	1	2
SMAD3	RANBP9	130	0	53	179	1	1
SMAD3	TSPYL2	0	0	146	164	1	1
SMAD3	KLF15	0	0	260	279	1	1
SMAD3	MAPK3	0	900	563	962	1	2
SMAD3	THY1	0	0	294	302	1	1
SMAD3	MYL12B	0	0	45	166	1	1
SMAD3	SLC11A2	0	0	73	171	1	1
SMAD3	NIPBL	0	0	94	252	1	1
SMAD3	JUNB	462	900	325	964	1	1
SMAD3	TFDP1	0	900	61	905	1	1
SMAD3	SQSTM1	184	0	108	241	1	2
SMAD3	BNIP3	0	0	171	171	1	2
SMAD3	SELP	0	0	136	169	1	1
SMAD3	SELL	0	0	234	247	1	1
SMAD3	HOXA5	0	0	95	153	1	1
SMAD3	FGF1	0	0	233	232	1	1
SMAD3	PRDM14	0	0	134	233	1	1
SMAD3	SOX2	0	0	578	643	1	2
SMAD3	CFC1	0	900	96	918	1	1
SMAD3	DES	0	0	0	280	1	2
SMAD3	PSEN1	0	0	161	161	1	2
SMAD3	TP73	213	0	95	308	1	2
SMAD3	ATF2	270	900	700	977	1	1
SMAD3	RANGAP1	0	0	82	198	1	1
SMAD3	CRP	0	0	211	211	1	2
SMAD3	CLEC16A	0	0	144	235	1	2
SMAD3	BCL3	0	0	0	154	1	1
SMAD3	CTBP1	0	0	310	326	1	1
SMAD3	POFUT1	0	0	0	152	1	1
SMAD3	HSP90AA1	0	0	293	516	1	2
SMAD3	DDX4	131	0	61	168	1	1
SMAD3	HDAC4	270	0	982	986	1	2
SMAD3	ZMYM2	213	0	73	325	1	1
SMAD3	IL21	0	0	0	188	1	1
SMAD3	E2F7	0	0	181	207	1	1
SMAD3	S100A11	0	0	161	161	1	1
SMAD3	PRRX1	0	0	150	222	1	1
SMAD3	CUL1	462	800	194	908	1	1
SMAD3	CASP7	0	0	157	196	1	1
SMAD3	XPO4	0	0	584	584	1	1
SMAD3	ELAVL1	0	0	150	169	1	2
SMAD3	CSNK1D	459	0	96	528	1	1
SMAD3	THBS4	0	0	150	181	1	1
SMAD3	LGALS7	0	0	617	747	1	1
SMAD3	GTF2IRD1	213	0	108	304	1	1
SMAD3	PPP2R1B	0	0	140	170	1	1
SMAD3	CCL2	0	0	500	499	1	2
SMAD3	ALB	0	0	500	522	1	2
SMAD3	UTRN	0	0	112	216	1	1
SMAD3	CD68	0	0	295	310	1	2
SMAD3	SFRP5	0	0	135	170	1	1
SMAD3	CARD17	0	0	0	188	1	1
SMAD3	CREB3L3	0	0	66	160	1	1
SMAD3	EIF4A1	0	0	63	184	1	1
SMAD3	SNAI2	0	0	612	676	1	1
SMAD3	ROCK1	0	0	303	366	1	2
SMAD3	HNF1B	0	0	166	167	1	1
SMAD3	PHACTR1	0	0	228	227	1	1
SMAD3	ONECUT1	0	0	150	187	1	1
SMAD3	SPARC	0	0	294	319	1	2
SMAD3	IL17F	0	0	218	218	1	1
SMAD3	DOK1	0	0	624	624	1	1
SMAD3	HOXA2	0	0	117	173	1	1
SMAD3	BIRC3	0	0	156	175	1	1
SMAD3	WNT9B	0	0	228	321	1	1
SMAD3	IL4	0	0	468	468	1	1
SMAD3	PRMT3	0	0	0	158	1	1
SMAD3	LEF1	486	0	883	947	1	1
SMAD3	PDGFRB	0	0	324	353	1	2
SMAD3	NUMB	0	0	212	230	1	1
SMAD3	EP300	937	900	989	999	1	2
SMAD3	PRMT6	0	0	0	157	1	1
SMAD3	CDK5	0	0	208	225	1	2
SMAD3	CDH1	0	900	685	968	1	2
SMAD3	IGF2BP1	0	0	96	315	1	1
SMAD3	PRKCZ	0	0	134	202	1	1
SMAD3	ZCCHC14	111	0	349	396	1	1
SMAD3	FNDC5	0	0	212	212	1	1
SMAD3	PDGFRA	0	0	234	266	1	1
SMAD3	SIRT6	0	0	255	285	1	2
SMAD3	CAP2	0	0	108	163	1	1
SMAD3	WNT16	0	0	233	251	1	1
SMAD3	PDE4D	0	0	241	240	1	1
SMAD3	ACTC1	0	0	165	382	1	1
SMAD3	ALK	0	0	392	495	1	2
SMAD3	ROCK2	0	0	181	300	1	1
SMAD3	PAX6	270	0	721	790	1	1
SMAD3	WNT1	0	0	380	518	1	2
SMAD3	SKOR2	213	0	143	445	1	1
SMAD3	MAGI3	0	0	0	199	1	1
SMAD3	EIF5A2	0	0	154	153	1	1
SMAD3	ACVR2B	0	900	600	974	1	1
SMAD3	CRYGC	0	0	181	181	1	1
SMAD3	MAF	0	0	326	339	1	1
SMAD3	ZYX	0	0	166	193	1	1
SMAD3	GATA1	0	0	309	395	1	1
SMAD3	NODAL	0	900	303	939	1	1
SMAD3	MAP3K11	0	0	91	153	1	1
SMAD3	LOXL2	0	0	263	263	1	1
SMAD3	CCR1	0	0	142	156	1	1
SMAD3	FSTL3	0	0	276	303	1	1
SMAD3	PPP2CB	0	0	113	217	1	1
SMAD3	TDP2	111	0	651	677	1	1
SMAD3	COL4A1	0	0	334	421	1	1
SMAD3	EFEMP2	0	0	391	426	1	1
SMAD3	SNRNP70	130	0	73	159	1	1
SMAD3	HBZ	0	0	829	835	1	1
SMAD3	PSMD11	130	0	157	235	1	1
SMAD3	CDK11A	131	0	0	150	1	1
SMAD3	MMP16	0	0	134	288	1	1
SMAD3	MAP2K4	0	0	285	301	1	1
SMAD3	MUT	0	0	233	286	1	1
SMAD3	PRKAR1B	213	0	0	245	1	1
SMAD3	CTDSPL	0	900	0	909	1	1
SMAD3	FGF18	0	0	139	270	1	1
SMAD3	BRAF	0	0	74	159	1	2
SMAD3	CFC1B	0	0	0	174	1	1
SMAD3	FRZB	0	0	260	329	1	1
SMAD3	BMP1	0	0	325	372	1	1
SMAD3	MAPK8	600	800	452	954	1	2
SMAD3	ZNF217	0	0	124	199	1	1
SMAD3	PTK2	0	0	390	403	1	2
SMAD3	BHLHE40	0	0	202	216	1	1
SMAD3	CDC6	0	0	134	154	1	1
SMAD3	BMP2	0	0	637	809	1	1
SMAD3	PROC	0	900	0	901	1	1
SMAD3	PRTN3	270	0	94	325	1	1
SMAD3	SP4	0	0	57	252	1	1
SMAD3	EGF	0	0	545	553	1	2
SMAD3	HNF1A	0	0	166	178	1	1
SMAD3	IGFBP1	0	0	139	204	1	1
SMAD3	PLAU	0	0	321	348	1	1
SMAD3	FBLN5	0	0	229	262	1	1
SMAD3	RAC3	0	0	61	159	1	2
SMAD3	PDP1	0	0	52	270	1	1
SMAD3	PPM1L	0	0	0	153	1	1
SMAD3	CXCL11	0	0	384	384	1	1
SMAD3	WDR36	0	0	218	218	1	1
SMAD3	CYCS	0	0	299	299	1	2
SMAD3	DUSP12	0	0	150	169	1	1
SMAD3	GADD45B	0	0	261	288	1	1
SMAD3	TRAF6	0	0	932	935	1	2
SMAD3	SESN3	0	0	113	152	1	1
SMAD3	PYHIN1	0	0	263	263	1	1
SMAD3	FLCN	0	0	108	163	1	1
SMAD3	IL18BP	0	0	162	178	1	1
SMAD3	VCAN	0	0	264	264	1	1
SMAD3	CXCL9	0	0	164	163	1	1
SMAD3	LPL	0	0	181	181	1	1
SMAD3	TEK	0	0	262	310	1	1
SMAD3	PPARA	0	0	506	520	1	2
SMAD3	CCR2	0	0	294	305	1	2
SMAD3	DNPEP	0	0	150	216	1	1
SMAD3	COL4A4	0	0	66	171	1	1
SMAD3	CYP2E1	0	0	168	181	1	2
SMAD3	PDCD4	0	0	572	577	1	2
SMAD3	HSPB3	0	0	211	211	1	1
SMAD3	XPO5	0	0	246	262	1	1
SMAD3	TRPC6	0	0	142	166	1	1
SMAD3	HSP90B1	0	0	66	192	1	1
SMAD3	PLAUR	0	0	217	217	1	1
SMAD3	EPB41L5	257	0	0	287	1	1
SMAD3	PIK3R1	116	0	251	309	1	1
SMAD3	DICER1	0	0	374	439	1	1
SMAD3	GATA4	0	0	532	636	1	2
SMAD3	ETV5	0	0	125	172	1	1
SMAD3	PCBP2	0	0	95	192	1	1
SMAD3	IRF2	0	0	181	181	1	1
SMAD3	HSPA4	432	0	917	950	1	1
SMAD3	PPARGC1A	0	0	391	390	1	2
SMAD3	PSG5	0	0	154	153	1	1
SMAD3	ADAM10	0	0	137	243	1	1
SMAD3	CPSF7	390	0	0	390	1	1
SMAD3	TRIM33	874	600	945	997	1	1
SMAD3	APC2	0	0	66	213	1	1
SMAD3	SOX11	0	0	181	205	1	1
SMAD3	NR0B2	0	0	447	463	1	1
SMAD3	IFNA1	0	0	233	232	1	1
SMAD3	WNT5A	0	0	401	450	1	2
SMAD3	ILK	0	0	379	402	1	1
SMAD3	RAB11FIP5	131	0	0	174	1	1
SMAD3	PTPRN2	0	0	416	441	1	1
SMAD3	FOXN3	0	0	180	250	1	1
SMAD3	ITGAE	0	0	278	278	1	1
SMAD3	IL15	0	0	292	292	1	1
SMAD3	IL2RA	0	0	289	543	1	1
SMAD3	ACP5	0	0	183	183	1	1
SMAD3	HNF4G	0	0	60	167	1	1
SMAD3	TOP1	0	0	141	163	1	1
SMAD3	CBX4	0	0	48	152	1	1
SMAD3	WWTR1	0	800	481	909	1	1
SMAD3	USP15	675	600	181	884	1	1
SMAD3	TBX5	0	0	181	210	1	1
SMAD3	GNAQ	0	0	142	180	1	1
SMAD3	DVL1	270	0	683	801	1	1
SMAD3	ZNF25	0	0	113	179	1	1
SMAD3	ADORA1	0	0	97	229	1	1
SMAD3	RICTOR	0	0	234	271	1	2
SMAD3	IBSP	0	0	227	321	1	1
SMAD3	YTHDF2	131	0	448	502	1	1
SMAD3	DUSP4	0	0	166	209	1	1
SMAD3	VPS39	0	0	387	386	1	1
SMAD3	LAG3	0	0	181	181	1	1
SMAD3	ACTA1	0	0	294	428	1	1
SMAD3	CCNT1	270	900	48	926	1	1
SMAD3	PBK	0	0	66	158	1	1
SMAD3	INHBA	0	900	390	944	1	1
SMAD3	LEMD3	786	0	404	895	1	1
SMAD3	FLNA	72	0	389	513	1	1
SMAD3	LRP5	0	0	324	364	1	1
SMAD3	DLX2	0	0	125	158	1	1
SMAD3	JPH3	207	0	0	207	1	1
SMAD3	TCF3	0	900	436	943	1	1
SMAD3	ST13	0	0	162	161	1	2
SMAD3	BACH1	270	0	0	317	1	1
SMAD3	TOP2A	0	0	96	167	1	1
SMAD3	OPA1	257	0	73	309	1	2
SMAD3	CDKN2D	0	0	96	175	1	1
SMAD3	FZD2	0	0	151	220	1	1
SMAD3	BRCA1	486	0	460	710	1	2
SMAD3	PITX1	270	0	459	588	1	1
SMAD3	PDGFB	0	0	322	333	1	2
SMAD3	STK11	0	0	261	277	1	2
SMAD3	PAX9	0	0	117	205	1	1
SMAD3	USP38	0	0	211	225	1	1
SMAD3	AREG	0	0	210	210	1	1
SMAD3	FRS2	0	0	150	191	1	1
SMAD3	DAB2IP	0	0	142	150	1	2
SMAD3	MYL9	0	0	122	160	1	1
SMAD3	PAPPA	130	0	66	152	1	1
SMAD3	TDGF1	0	900	359	949	1	1
SMAD3	MAP3K13	0	0	71	164	1	1
SMAD3	CFLAR	111	0	193	251	1	2
SMAD3	EGFR	0	0	614	647	1	2
SMAD3	TSC22D4	131	0	0	174	1	1
SMAD3	TNFRSF4	0	0	204	204	1	1
SMAD3	FGFR3	0	0	341	398	1	1
SMAD3	TSLP	0	0	294	294	1	1
SMAD3	SLC2A1	0	0	193	214	1	2
SMAD3	AMHR2	0	0	248	315	1	1
SMAD3	FLNB	0	0	715	731	1	1
SMAD3	TP53	494	0	972	985	1	2
SMAD3	LCN2	0	0	183	183	1	1
SMAD3	HECTD2	0	0	0	192	1	1
SMAD3	HOXA13	0	0	113	171	1	1
SMAD3	MDM2	0	0	391	390	1	2
SMAD3	DCN	0	0	401	430	1	2
SMAD3	SOX18	0	0	127	153	1	1
SMAD3	TGM2	74	0	231	282	1	2
SMAD3	EDA	0	0	265	281	1	1
SMAD3	TNFRSF11B	0	0	244	243	1	1
SMAD3	PAEP	270	0	317	480	1	1
SMAD3	LAMA4	0	0	128	171	1	1
SMAD3	HDAC2	0	900	484	948	1	1
SMAD3	MAP3K7	600	0	813	929	1	2
SMAD3	KPNA3	0	0	61	210	1	1
SMAD3	NUP153	270	900	74	931	1	1
SMAD3	KRT10	270	0	76	296	1	1
SMAD3	WNT4	0	0	297	355	1	1
SMAD3	RBL1	270	900	945	995	1	1
SMAD3	CARD9	0	0	166	165	1	1
SMAD3	RREB1	0	0	112	178	1	1
SMAD3	NCOR2	0	600	211	696	1	1
SMAD3	IRAK1	0	0	228	313	1	1
SMAD3	ADAMTS1	0	0	138	221	1	1
SMAD3	RAF1	0	0	213	272	1	2
SMAD3	NR4A1	111	0	276	343	1	2
SMAD3	CHST11	0	0	204	219	1	1
SMAD3	KLF10	0	0	338	396	1	1
SMAD3	CDH3	0	0	208	237	1	1
SMAD3	PPARD	0	0	150	277	1	1
SMAD3	SFTPC	0	0	202	202	1	1
SMAD3	ZSCAN1	0	0	143	165	1	1
SMAD3	BRD4	0	0	269	334	1	2
SMAD3	CLU	0	0	206	206	1	2
SMAD3	HUWE1	0	0	72	201	1	1
SMAD3	MELK	0	0	46	256	1	1
SMAD3	MIA3	0	0	310	309	1	1
SMAD3	RNF111	753	600	465	944	1	1
SMAD3	PTPN4	0	900	0	902	1	1
SMAD3	APAF1	0	0	198	221	1	2
SMAD3	HDAC6	0	0	282	372	1	2
SMAD3	CDH2	0	0	600	606	1	1
SMAD3	RBMS3	0	0	0	161	1	1
SMAD3	JAK2	0	0	363	414	1	2
SMAD3	BRD7	0	0	490	503	1	1
SMAD3	GDNF	0	0	160	161	1	2
SMAD3	ITGB8	0	0	194	211	1	1
SMAD3	HBEGF	0	0	243	242	1	1
SMAD3	NCOA1	270	900	448	956	1	1
SMAD3	UBR5	0	0	45	197	1	1
SMAD3	MMP15	0	0	90	304	1	1
SMAD3	KRT5	0	0	203	203	1	1
SMAD3	PRKAR2A	213	0	0	261	1	1
SMAD3	MUC5AC	0	900	143	917	1	1
SMAD3	MYH6	0	0	286	286	1	1
SMAD3	SERPINH1	0	0	218	266	1	1
SMAD3	SOX4	0	0	342	361	1	1
SMAD3	PCSK5	0	0	66	185	1	1
SMAD3	PHKB	0	0	0	176	1	1
SMAD3	ITGA5	0	0	212	260	1	1
SMAD3	WNT7A	0	0	321	337	1	1
SMAD3	UBE2G1	0	0	0	170	1	1
SMAD3	MED6	270	0	0	270	1	1
SMAD3	KLK3	0	0	175	187	1	1
SMAD3	PAX2	0	0	155	211	1	1
SMAD3	FSHB	0	0	218	290	1	1
SMAD3	IL6R	0	0	320	319	1	1
SMAD3	SUMO2	0	0	157	183	1	1
SMAD3	LEFTY1	270	0	209	500	1	1
SMAD3	CXCL8	0	0	452	459	1	2
SMAD3	RAB5A	0	0	107	251	1	2
SMAD3	BTG4	0	0	0	159	1	1
SMAD3	BMP15	0	0	261	370	1	1
SMAD3	BAG3	270	0	65	404	1	2
SMAD3	ISL1	145	0	118	242	1	1
SMAD3	FZD4	0	0	181	222	1	1
SMAD3	POSTN	0	0	403	420	1	1
SMAD3	TRIM27	0	0	54	175	1	1
SMAD3	NEDD4	680	0	353	822	1	2
SMAD3	WWC2	0	0	0	174	1	1
SMAD3	IKBKE	0	0	103	164	1	1
SMAD3	BAZ1A	0	0	57	155	1	1
SMAD3	WNT2B	0	0	261	402	1	1
SMAD3	DDR2	0	0	161	181	1	1
SMAD3	APP	73	0	181	225	1	2
SMAD3	VENTX	0	0	0	151	1	1
SMAD3	EGR1	0	0	457	483	1	2
SMAD3	S1PR3	0	0	206	223	1	1
SMAD3	RANBP17	0	0	0	168	1	1
SMAD3	KLHL9	0	0	451	451	1	1
SMAD3	MSH6	0	0	151	150	1	1
SMAD3	CTNNB1	816	0	988	998	1	2
SMAD3	MYF5	0	0	308	401	1	1
SMAD3	HRAS	0	0	458	506	1	2
SMAD3	TIMP4	0	0	183	183	1	1
SMAD3	MED15	270	900	136	940	1	1
SMAD3	E2F2	0	0	248	264	1	1
SMAD3	CD163	0	0	181	186	1	1
SMAD3	JARID2	0	0	155	154	1	1
SMAD3	PSMC6	0	0	152	201	1	1
SMAD3	MTOR	0	0	466	478	1	2
SMAD3	KLF17	0	0	442	457	1	1
SMAD3	MMP1	0	0	384	401	1	1
SMAD3	ARAF	0	0	75	172	1	1
SMAD3	MOSPD1	0	0	54	197	1	1
SMAD3	RRAS	0	0	95	190	1	1
SMAD3	CXCR4	0	0	375	385	1	2
SMAD3	HIST1H4F	0	0	203	203	1	1
SMAD3	CYR61	0	0	248	298	1	1
SMAD3	GZMB	0	0	251	262	1	1
SMAD3	NPHS1	0	0	298	364	1	1
SMAD3	OCLN	0	0	341	360	1	1
SMAD3	PLEK	0	0	142	160	1	1
SMAD3	STAT1	0	0	468	489	1	2
SMAD3	CTRL	0	0	180	234	1	2
SMAD3	TBL1XR1	0	0	113	232	1	1
SMAD3	MOG	0	0	171	171	1	1
SMAD3	IGFBP7	0	0	213	223	1	1
SMAD3	MAP3K2	0	0	141	159	1	1
SMAD3	PPP4C	0	0	47	186	1	1
SMAD3	ETS2	0	0	282	366	1	1
SMAD3	ACAN	0	0	392	417	1	1
SMAD3	SMN1	0	0	342	378	1	1
SMAD3	USP9X	270	0	167	398	1	1
SMAD3	FGF14	0	0	54	198	1	1
SMAD3	CREB1	0	0	505	519	1	2
SMAD3	APC	0	0	261	377	1	1
SMAD3	IL2RB	0	0	294	309	1	1
SMAD3	WWP1	730	0	321	844	1	1
SMAD3	DHX9	0	0	128	235	1	1
SMAD3	GDF9	0	0	533	593	1	1
SMAD3	CREBBP	870	900	965	999	1	1
SMAD3	DGCR8	0	0	263	279	1	1
SMAD3	RECK	0	0	173	191	1	1
SMAD3	SDHB	0	0	249	248	1	1
SMAD3	UBE2D3	0	900	0	903	1	1
SMAD3	ESRRA	0	0	150	192	1	1
SMAD3	CYP17A1	0	0	122	156	1	1
SMAD3	TMEM119	0	0	146	182	1	1
SMAD3	RUNX1T1	0	0	459	459	1	1
SMAD3	WNT11	0	0	295	311	1	1
SMAD3	ZFX	0	0	137	200	1	1
SMAD3	SIRT2	0	0	236	587	1	2
SMAD3	IL4R	0	0	218	218	1	1
SMAD3	TRIP12	0	0	0	234	1	1
SMAD3	TTC4	0	0	941	942	1	1
SMAD3	CTNND1	0	0	158	178	1	1
SMAD3	RELA	131	0	524	570	1	2
SMAD3	CARM1	0	0	112	188	1	2
SMAD3	RORA	0	0	296	296	1	1
SMAD3	MFAP2	0	0	150	176	1	1
SMAD3	KLF6	0	0	496	698	1	1
SMAD3	NFKB1	0	0	324	389	1	2
SMAD3	HOXB9	0	0	81	153	1	1
SMAD3	TLR10	0	0	81	153	1	1
SMAD3	MMP20	0	0	57	275	1	1
SMAD3	CTNNBIP1	0	0	177	207	1	1
SMAD3	ZAP70	0	0	156	231	1	1
SMAD3	STAT4	0	0	267	354	1	1
SMAD3	ZIC1	0	0	113	168	1	1
SMAD3	SF3A1	213	0	0	233	1	1
SMAD3	ZGLP1	0	0	0	159	1	1
SMAD3	WIF1	0	0	195	212	1	1
SMAD3	ELF5	0	0	432	435	1	1
SMAD3	PTPN14	0	900	97	907	1	1
SMAD3	IGF2BP2	0	0	91	166	1	1
SMAD3	GNRHR	0	0	167	232	1	1
SMAD3	GSTM3	0	0	0	224	1	1
SMAD3	DACT1	0	0	142	157	1	1
SMAD3	SPDEF	0	0	144	195	1	1
SMAD3	ABL1	0	0	310	373	1	1
SMAD3	HIST4H4	0	0	203	203	1	1
SMAD3	CX3CL1	0	0	183	183	1	1
SMAD3	EBF1	0	0	181	203	1	1
SMAD3	MAP2K7	0	0	402	418	1	1
SMAD3	HDAC10	0	0	113	174	1	1
SMAD3	TCF7L2	0	0	324	545	1	1
SMAD3	HAMP	0	0	165	165	1	1
SMAD3	HEYL	130	0	165	259	1	1
SMAD3	GREM1	0	0	392	399	1	1
SMAD3	GAPDH	0	0	630	639	1	2
SMAD3	DUSP5	0	0	142	199	1	1
SMAD3	PML	270	900	134	933	1	2
SMAD3	WWC1	0	0	123	245	1	1
SMAD3	FGFR2	0	0	263	326	1	1

Ontologies

ID	Category	Term	Effect	Evidence
GO:0017151	Molecular Function	DEAD/H-box RNA helicase binding	enables	IPI
GO:0003677	Molecular Function	DNA binding	enables	IDA
GO:0001228	Molecular Function	DNA-binding transcription activator activity, RNA polymerase II-specific	enables	IDA
GO:0001228	Molecular Function	DNA-binding transcription activator activity, RNA polymerase II-specific	enables	IMP
GO:0001228	Molecular Function	DNA-binding transcription activator activity, RNA polymerase II-specific	enables	ISS
GO:0003700	Molecular Function	DNA-binding transcription factor activity	contributes_to	IDA
GO:0003700	Molecular Function	DNA-binding transcription factor activity	enables	IDA
GO:0003700	Molecular Function	DNA-binding transcription factor activity	enables	IMP
GO:0000981	Molecular Function	DNA-binding transcription factor activity, RNA polymerase II-specific	enables	IBA
GO:0000981	Molecular Function	DNA-binding transcription factor activity, RNA polymerase II-specific	enables	IDA
GO:0000981	Molecular Function	DNA-binding transcription factor activity, RNA polymerase II-specific	enables	ISA
GO:0140297	Molecular Function	DNA-binding transcription factor binding	enables	IPI
GO:0001217	Molecular Function	DNA-binding transcription repressor activity	enables	IDA
GO:0070411	Molecular Function	I-SMAD binding	enables	IBA
GO:0070412	Molecular Function	R-SMAD binding	enables	IPI
GO:0000978	Molecular Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	enables	IBA
GO:0000978	Molecular Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	enables	IDA
GO:0061629	Molecular Function	RNA polymerase II-specific DNA-binding transcription factor binding	enables	IPI
GO:0043425	Molecular Function	bHLH transcription factor binding	enables	IPI
GO:0008013	Molecular Function	beta-catenin binding	enables	IEA
GO:0031490	Molecular Function	chromatin DNA binding	enables	IEA
GO:0000987	Molecular Function	cis-regulatory region sequence-specific DNA binding	enables	IC
GO:0000987	Molecular Function	cis-regulatory region sequence-specific DNA binding	enables	IDA
GO:0000987	Molecular Function	cis-regulatory region sequence-specific DNA binding	enables	IMP
GO:0070410	Molecular Function	co-SMAD binding	enables	IPI
GO:0005518	Molecular Function	collagen binding	enables	IEA
GO:0042802	Molecular Function	identical protein binding	enables	IPI
GO:0035259	Molecular Function	nuclear glucocorticoid receptor binding	enables	IPI
GO:0031962	Molecular Function	nuclear mineralocorticoid receptor binding	enables	IPI
GO:0016922	Molecular Function	nuclear receptor binding	enables	IPI
GO:0019902	Molecular Function	phosphatase binding	enables	IPI
GO:1990841	Molecular Function	promoter-specific chromatin binding	enables	IEA
GO:0005515	Molecular Function	protein binding	enables	IPI
GO:0042803	Molecular Function	protein homodimerization activity	enables	IPI
GO:0019901	Molecular Function	protein kinase binding	enables	IPI
GO:0043565	Molecular Function	sequence-specific DNA binding	enables	IDA
GO:0032810	Molecular Function	sterol response element binding	enables	IGI
GO:0000976	Molecular Function	transcription cis-regulatory region binding	enables	IDA
GO:0001223	Molecular Function	transcription coactivator binding	enables	IPI
GO:0001222	Molecular Function	transcription corepressor binding	enables	IPI
GO:0005160	Molecular Function	transforming growth factor beta receptor binding	enables	IPI
GO:0043130	Molecular Function	ubiquitin binding	enables	IDA
GO:0031625	Molecular Function	ubiquitin protein ligase binding	enables	IPI
GO:0008270	Molecular Function	zinc ion binding	enables	IDA
GO:0007254	Biological Process	JNK cascade	involved_in	IEA
GO:0060395	Biological Process	SMAD protein signal transduction	involved_in	IBA
GO:0060395	Biological Process	SMAD protein signal transduction	involved_in	IDA
GO:0060395	Biological Process	SMAD protein signal transduction	acts_upstream_of	IMP
GO:0060395	Biological Process	SMAD protein signal transduction	involved_in	NAS
GO:0042110	Biological Process	T cell activation	involved_in	IEA
GO:0006919	Biological Process	activation of cysteine-type endopeptidase activity involved in apoptotic process	involved_in	IMP
GO:0032924	Biological Process	activin receptor signaling pathway	involved_in	IBA
GO:0032924	Biological Process	activin receptor signaling pathway	involved_in	IMP
GO:0030325	Biological Process	adrenal gland development	involved_in	IEA
GO:0009653	Biological Process	anatomical structure morphogenesis	involved_in	IBA
GO:0030154	Biological Process	cell differentiation	involved_in	IBA
GO:0045216	Biological Process	cell-cell junction organization	involved_in	IMP
GO:0071560	Biological Process	cellular response to transforming growth factor beta stimulus	involved_in	IDA
GO:0098586	Biological Process	cellular response to virus	involved_in	IEA
GO:0048589	Biological Process	developmental growth	involved_in	IEA
GO:0048701	Biological Process	embryonic cranial skeleton morphogenesis	involved_in	IEA
GO:0048617	Biological Process	embryonic foregut morphogenesis	involved_in	IEA
GO:0009880	Biological Process	embryonic pattern specification	involved_in	IEA
GO:0007492	Biological Process	endoderm development	involved_in	IEA
GO:0097191	Biological Process	extrinsic apoptotic signaling pathway	involved_in	IMP
GO:0001947	Biological Process	heart looping	involved_in	IEA
GO:0006955	Biological Process	immune response	involved_in	IMP
GO:0002520	Biological Process	immune system development	involved_in	IEA
GO:0001701	Biological Process	in utero embryonic development	involved_in	IEA
GO:0070306	Biological Process	lens fiber cell differentiation	involved_in	IEA
GO:0001889	Biological Process	liver development	involved_in	IEA
GO:0001707	Biological Process	mesoderm formation	involved_in	IEA
GO:0043066	Biological Process	negative regulation of apoptotic process	involved_in	IEA
GO:1903243	Biological Process	negative regulation of cardiac muscle hypertrophy in response to stress	involved_in	IEA
GO:0030308	Biological Process	negative regulation of cell growth	involved_in	IDA
GO:0008285	Biological Process	negative regulation of cell population proliferation	involved_in	IMP
GO:0051481	Biological Process	negative regulation of cytosolic calcium ion concentration	involved_in	IDA
GO:0045599	Biological Process	negative regulation of fat cell differentiation	involved_in	IDA
GO:0010629	Biological Process	negative regulation of gene expression	acts_upstream_of	IMP
GO:0050728	Biological Process	negative regulation of inflammatory response	involved_in	IEA
GO:0061767	Biological Process	negative regulation of lung blood pressure	involved_in	IEA
GO:1902894	Biological Process	negative regulation of miRNA transcription	involved_in	IMP
GO:0045668	Biological Process	negative regulation of osteoblast differentiation	involved_in	IEA
GO:0033689	Biological Process	negative regulation of osteoblast proliferation	involved_in	IEA
GO:0042177	Biological Process	negative regulation of protein catabolic process	involved_in	IEA
GO:0000122	Biological Process	negative regulation of transcription by RNA polymerase II	involved_in	IDA
GO:0000122	Biological Process	negative regulation of transcription by RNA polymerase II	involved_in	IMP
GO:0061045	Biological Process	negative regulation of wound healing	involved_in	IEA
GO:0038092	Biological Process	nodal signaling pathway	involved_in	IMP
GO:0002076	Biological Process	osteoblast development	involved_in	IEA
GO:0048340	Biological Process	paraxial mesoderm morphogenesis	involved_in	IEA
GO:0060039	Biological Process	pericardium development	involved_in	IEA
GO:0051091	Biological Process	positive regulation of DNA-binding transcription factor activity	involved_in	NAS
GO:0045893	Biological Process	positive regulation of DNA-templated transcription	involved_in	IDA
GO:0030501	Biological Process	positive regulation of bone mineralization	involved_in	IEA
GO:0090263	Biological Process	positive regulation of canonical Wnt signaling pathway	involved_in	IEA
GO:0030335	Biological Process	positive regulation of cell migration	involved_in	IEA
GO:0032332	Biological Process	positive regulation of chondrocyte differentiation	involved_in	IEA
GO:0010718	Biological Process	positive regulation of epithelial to mesenchymal transition	involved_in	IDA
GO:0010718	Biological Process	positive regulation of epithelial to mesenchymal transition	involved_in	IMP
GO:1901203	Biological Process	positive regulation of extracellular matrix assembly	involved_in	IDA
GO:1901203	Biological Process	positive regulation of extracellular matrix assembly	acts_upstream_of	IMP
GO:0051894	Biological Process	positive regulation of focal adhesion assembly	involved_in	IEA
GO:0010628	Biological Process	positive regulation of gene expression	involved_in	IDA
GO:0032731	Biological Process	positive regulation of interleukin-1 beta production	involved_in	IEA
GO:1902895	Biological Process	positive regulation of miRNA transcription	involved_in	IDA
GO:1902895	Biological Process	positive regulation of miRNA transcription	acts_upstream_of	IMP
GO:1902895	Biological Process	positive regulation of miRNA transcription	involved_in	IMP
GO:0045429	Biological Process	positive regulation of nitric oxide biosynthetic process	involved_in	IDA
GO:0050927	Biological Process	positive regulation of positive chemotaxis	involved_in	IEA
GO:0042307	Biological Process	positive regulation of protein import into nucleus	involved_in	NAS
GO:0051496	Biological Process	positive regulation of stress fiber assembly	involved_in	IEA
GO:0045944	Biological Process	positive regulation of transcription by RNA polymerase II	involved_in	IBA
GO:0045944	Biological Process	positive regulation of transcription by RNA polymerase II	involved_in	IDA
GO:0045944	Biological Process	positive regulation of transcription by RNA polymerase II	involved_in	IMP
GO:0032916	Biological Process	positive regulation of transforming growth factor beta3 production	involved_in	IEA
GO:0031053	Biological Process	primary miRNA processing	involved_in	TAS
GO:0050821	Biological Process	protein stabilization	involved_in	IEA
GO:0006355	Biological Process	regulation of DNA-templated transcription	involved_in	IDA
GO:0050678	Biological Process	regulation of epithelial cell proliferation	involved_in	IEA
GO:0050776	Biological Process	regulation of immune response	involved_in	IEA
GO:1902893	Biological Process	regulation of miRNA transcription	involved_in	IC
GO:0016202	Biological Process	regulation of striated muscle tissue development	involved_in	IEA
GO:0006357	Biological Process	regulation of transcription by RNA polymerase II	involved_in	IDA
GO:0017015	Biological Process	regulation of transforming growth factor beta receptor signaling pathway	involved_in	IMP
GO:0032909	Biological Process	regulation of transforming growth factor beta2 production	involved_in	IMP
GO:1990776	Biological Process	response to angiotensin	acts_upstream_of	IMP
GO:0001666	Biological Process	response to hypoxia	involved_in	IMP
GO:0023019	Biological Process	signal transduction involved in regulation of gene expression	involved_in	IEA
GO:0001756	Biological Process	somitogenesis	involved_in	IEA
GO:0030878	Biological Process	thyroid gland development	involved_in	IEA
GO:0060290	Biological Process	transdifferentiation	involved_in	IEA
GO:0007179	Biological Process	transforming growth factor beta receptor signaling pathway	involved_in	IBA
GO:0007179	Biological Process	transforming growth factor beta receptor signaling pathway	involved_in	IDA
GO:0001657	Biological Process	ureteric bud development	involved_in	IEA
GO:0042060	Biological Process	wound healing	involved_in	TAS
GO:0071141	Cellular Component	SMAD protein complex	part_of	IDA
GO:0000785	Cellular Component	chromatin	part_of	IDA
GO:0000785	Cellular Component	chromatin	part_of	ISA
GO:0005737	Cellular Component	cytoplasm	located_in	IDA
GO:0005829	Cellular Component	cytosol	located_in	IDA
GO:0005829	Cellular Component	cytosol	located_in	IGI
GO:0005829	Cellular Component	cytosol	located_in	TAS
GO:0071144	Cellular Component	heteromeric SMAD protein complex	part_of	IBA
GO:0071144	Cellular Component	heteromeric SMAD protein complex	part_of	IDA
GO:0005637	Cellular Component	nuclear inner membrane	located_in	IDA
GO:0005654	Cellular Component	nucleoplasm	located_in	IDA
GO:0005654	Cellular Component	nucleoplasm	located_in	TAS
GO:0005634	Cellular Component	nucleus	located_in	IDA
GO:0005634	Cellular Component	nucleus	located_in	IGI
GO:0005886	Cellular Component	plasma membrane	located_in	IEA
GO:0043235	Cellular Component	receptor complex	part_of	IMP
GO:0005667	Cellular Component	transcription regulator complex	part_of	IDA
GO:0005667	Cellular Component	transcription regulator complex	part_of	IPI

Pathways

Name	DB	ID
Signaling by NODAL	Reactome	R-HSA-1181150
Developmental Biology	Reactome	R-HSA-1266738
Cytokine Signaling in Immune system	Reactome	R-HSA-1280215
Signaling by Activin	Reactome	R-HSA-1502540
Signaling by NOTCH	Reactome	R-HSA-157118
Signal Transduction	Reactome	R-HSA-162582
Disease	Reactome	R-HSA-1643685
Immune System	Reactome	R-HSA-168256
Signaling by TGF-beta Receptor Complex	Reactome	R-HSA-170834
Generic Transcription Pathway	Reactome	R-HSA-212436
Downregulation of TGF-beta receptor signaling	Reactome	R-HSA-2173788
TGF-beta receptor signaling activates SMADs	Reactome	R-HSA-2173789
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer	Reactome	R-HSA-2173793
Downregulation of SMAD2/3:SMAD4 transcriptional activity	Reactome	R-HSA-2173795
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	Reactome	R-HSA-2173796
Loss of Function of SMAD4 in Cancer	Reactome	R-HSA-3304347
Loss of Function of SMAD2/3 in Cancer	Reactome	R-HSA-3304349
Signaling by TGF-beta Receptor Complex in Cancer	Reactome	R-HSA-3304351
SMAD2/3 Phosphorylation Motif Mutants in Cancer	Reactome	R-HSA-3304356
SMAD4 MH2 Domain Mutants in Cancer	Reactome	R-HSA-3311021
SMAD2/3 MH2 Domain Mutants in Cancer	Reactome	R-HSA-3315487
TGFBR1 KD Mutants in Cancer	Reactome	R-HSA-3656532
Loss of Function of TGFBR1 in Cancer	Reactome	R-HSA-3656534
Metabolism of proteins	Reactome	R-HSA-392499
Interleukin-1 family signaling	Reactome	R-HSA-446652
Signaling by Interleukins	Reactome	R-HSA-449147
Diseases of signal transduction by growth factor receptors and second messengers	Reactome	R-HSA-5663202
Infectious disease	Reactome	R-HSA-5663205
Deubiquitination	Reactome	R-HSA-5688426
Ub-specific processing proteases	Reactome	R-HSA-5689880
Post-translational protein modification	Reactome	R-HSA-597592
RNA Polymerase II Transcription	Reactome	R-HSA-73857
Gene expression (Transcription)	Reactome	R-HSA-74160
Transcriptional regulation by RUNX3	Reactome	R-HSA-8878159
RUNX3 regulates CDKN1A transcription	Reactome	R-HSA-8941855
RUNX3 regulates BCL2L11 (BIM) transcription	Reactome	R-HSA-8952158
Signaling by TGFB family members	Reactome	R-HSA-9006936
Interleukin-37 signaling	Reactome	R-HSA-9008059
Signaling by NOTCH4	Reactome	R-HSA-9013694
NOTCH4 Intracellular Domain Regulates Transcription	Reactome	R-HSA-9013695
FOXO-mediated transcription	Reactome	R-HSA-9614085
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes	Reactome	R-HSA-9615017
FOXO-mediated transcription of cell cycle genes	Reactome	R-HSA-9617828
SARS-CoV-1 Infection	Reactome	R-HSA-9678108
SARS-CoV Infections	Reactome	R-HSA-9679506
SARS-CoV-1-host interactions	Reactome	R-HSA-9692914
SARS-CoV-1 targets host intracellular signalling and regulatory pathways	Reactome	R-HSA-9735871
Germ layer formation at gastrulation	Reactome	R-HSA-9754189
Gastrulation	Reactome	R-HSA-9758941
Formation of axial mesoderm	Reactome	R-HSA-9796292
Formation of definitive endoderm	Reactome	R-HSA-9823730
Viral Infection Pathways	Reactome	R-HSA-9824446
Neuroinflammation and glutamatergic signaling (WP5083)	WikiPathways	WP5083_r120385
Integrated cancer pathway (WP1971)	WikiPathways	WP1971_r117762
Hypothesized pathways in pathogenesis of cardiovascular disease (WP3668)	WikiPathways	WP3668_r123393
Canonical and non-canonical TGF-B signaling (WP3874)	WikiPathways	WP3874_r116461
TGF-beta signaling pathway (WP366)	WikiPathways	WP366_r120697
TGF-beta receptor signaling in skeletal dysplasias (WP4816)	WikiPathways	WP4816_r116440
Chromosomal and microsatellite instability in colorectal cancer (WP4216)	WikiPathways	WP4216_r123363
Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling (WP3850)	WikiPathways	WP3850_r121711
Hepatitis B infection (WP4666)	WikiPathways	WP4666_r123495
Endoderm differentiation (WP2853)	WikiPathways	WP2853_r116557
Hippo signaling regulation pathways (WP4540)	WikiPathways	WP4540_r120395
Extracellular vesicle-mediated signaling in recipient cells (WP2870)	WikiPathways	WP2870_r106411
Cell cycle (WP179)	WikiPathways	WP179_r122978
Mesodermal commitment pathway (WP2857)	WikiPathways	WP2857_r118395
Angiotensin II receptor type 1 pathway (WP5036)	WikiPathways	WP5036_r119016
Epithelial to mesenchymal transition in colorectal cancer (WP4239)	WikiPathways	WP4239_r118997
TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition (WP3859)	WikiPathways	WP3859_r117840
Adipogenesis (WP236)	WikiPathways	WP236_r105873
SARS-CoV-2 innate immunity evasion and cell-specific immune response (WP5039)	WikiPathways	WP5039_r124653
Burn wound healing (WP5055)	WikiPathways	WP5055_r122621
Ovarian infertility (WP34)	WikiPathways	WP34_r124177
Androgen receptor signaling pathway (WP138)	WikiPathways	WP138_r122133
DNA damage response (only ATM dependent) (WP710)	WikiPathways	WP710_r116542
Progeria-associated lipodystrophy (WP5103)	WikiPathways	WP5103_r119170
TGF-beta receptor signaling (WP560)	WikiPathways	WP560_r117838
Overlap between signal transduction pathways contributing to LMNA laminopathies (WP4879)	WikiPathways	WP4879_r123415
Envelope proteins and their potential roles in EDMD physiopathology (WP4535)	WikiPathways	WP4535_r109210
NRP1-triggered signaling pathways in pancreatic cancer (WP5144)	WikiPathways	WP5144_r120537
Hepatitis C and hepatocellular carcinoma (WP3646)	WikiPathways	WP3646_r116732
Pancreatic adenocarcinoma pathway (WP4263)	WikiPathways	WP4263_r123405
Vitamin D in inflammatory diseases (WP4482)	WikiPathways	WP4482_r121703
AGE/RAGE pathway (WP2324)	WikiPathways	WP2324_r120674
Neovascularisation processes (WP4331)	WikiPathways	WP4331_r107654

Transcripts

Accession	Version	MolecularType	Name	NCBI	Comments
NM_001407011	1	mRNA	transcript variant 5	NC_000015	Reference
NM_005902	4	mRNA	transcript variant 1	NC_000015	Reference
NM_001407013	1	mRNA	transcript variant 7	NC_000015	Reference
NM_001407012	1	mRNA	transcript variant 6	NC_000015	Reference
NM_001407014	1	mRNA	transcript variant 8	NC_000015	Reference
NM_001145102	2	mRNA	transcript variant 2	NC_000015	Reference
NM_001407015	1	mRNA	transcript variant 9	NC_000015	Reference
NM_001407016	1	mRNA	transcript variant 10	NC_000015	Reference
NM_001145103	2	mRNA	transcript variant 3	NC_000015	Reference
NM_001145104	2	mRNA	transcript variant 4	NC_000015	Reference
NM_001407017	1	mRNA	transcript variant 11	NC_000015	Reference